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Sample records for californium 242

  1. Historical Review of Californium-252 Discovery and Development

    Science.gov (United States)

    Stoddard, D. H.

    1985-01-01

    This paper discusses the discovery and history of californium 252. This isotope may be synthesized by irradiating plutonium 239, plutonium 242, americium 243, or curium 244 with neutrons in a nuclear reactor. Various experiments and inventions involving Cf conducted at the Savannah River Plant are discussed. The evolution of radiotherapy using californium 252 is reviewed. (PLG)

  2. Californium Electrodepositions at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Boll, Rose Ann [ORNL

    2015-01-01

    Electrodepositions of californium isotopes were successfully performed at Oak Ridge National Laboratory (ORNL) during the past year involving two different types of deposition solutions, ammonium acetate (NH4C2H3O2) and isobutanol ((CH3)2CHCH2OH). A californium product that was decay enriched in 251Cf was recovered for use in super-heavy element (SHE) research. This neutron-rich isotope, 251Cf, provides target material for SHE research for the potential discovery of heavier isotopes of Z=118. The californium material was recovered from aged 252Cf neutron sources in storage at ORNL. These sources have decayed for over 30 years, thus providing material with a very high 251Cf-to-252Cf ratio. After the source capsules were opened, the californium was purified and then electrodeposited using the isobutanol method onto thin titanium foils for use in an accelerator at the Joint Institute for Nuclear Research in Dubna, Russia. Another deposition method, ammonium acetate, was used to produce a deposition containing 1.7 0.1 Ci of 252Cf onto a stainless steel substrate. This was the largest single electrodeposition of 252Cf ever prepared. The 252Cf material was initially purified using traditional ion exchange media, such as AG50-AHIB and AG50-HCl, and further purified using a TEVA-NH4SCN system to remove any lanthanides, resulting in the recovery of 3.6 0.1 mg of purified 252Cf. The ammonium acetate deposition was run with a current of 1.0 amp, resulting in a 91.5% deposition yield. Purification and handling of the highly radioactive californium material created additional challenges in the production of these sources.

  3. Production, Distribution, and Applications of Californium-252 Neutron Sources

    Energy Technology Data Exchange (ETDEWEB)

    Balo, P.A.; Knauer, J.B.; Martin, R.C.

    1999-10-03

    The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6-year half-life. A source the size of a person's little finger can emit up to 10{sup 11} neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory (ORNL). DOE sells The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6- year half-life. A source the size of a person's little finger can emit up to 10 neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory(ORNL). DOE sells {sup 252}Cf to commercial

  4. Teratogenic effect of Californium-252 irradiation in rats

    Energy Technology Data Exchange (ETDEWEB)

    Satow, Yukio; Lee, Juing-Yi; Hori, Hiroshi; Okuda, Hiroe; Tsuchimoto, Shigeo; Sawada, Shozo; Yokoro, Kenjiro (Hiroshima Univ. (Japan). Research Inst. for Nuclear Medicine and Biology)

    1989-06-01

    The teratogenicity of Californium-252 (Cf-252) irradiation which generates approximately 70% 2.3 MeV fast neutron and 30% gamma rays was evaluated. A single whole body exposure of Cf-252 at various doses was given to pregnant rats on day 8 or 9 of pregnancy, followed by microscopic autopsy of the fetuses at the terminal stage of pregnancy to search for external and internal malformations. For comparison, pregnant rats were irradiated with various doses of Cobalt-60 (Co-60) standard gamma rays at the same dose rate (1 rad/min.). The doses were 20-120 rad of Cf-252 and 80-220 rad of Co-60. Using frequency of radiation induced malformations observed on day 8 of pregnancy as an index, relative biological effectiveness (RBE) of 2.3-2.7 was obtained from the straight line obtained by modifying by the least squares method the frequency curves of malformed fetuses in total implants and in surviving fetuses. The types of malformations induced by Cf-252 and Co-60 irradiation were alike. Using fetal LD/sub 50/ as an index, 2.4 was obtained as RBE when irradiated on day 8 of pregnancy and 3.1 as that when irradiated on day 9. The results showed that Cf-252 had stronger a teratogenic effect than Co-60 gamma rays. (author).

  5. 48 CFR 242.7302 - Requirements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requirements. 242.7302 Section 242.7302 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT.../Pension Review 242.7302 Requirements. Follow the procedures at PGI 242.7302 to determine if a CIPR...

  6. 48 CFR 242.7303 - Responsibilities.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Responsibilities. 242.7303 Section 242.7303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT.../Pension Review 242.7303 Responsibilities. Follow the procedures at PGI 242.7303 when conducting a CIPR....

  7. 32 CFR 242.7 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 242.7 Section 242.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... SCIENCES § 242.7 Responsibilities. (a) The President of the University shall: (1) Develop and...

  8. 25 CFR 242.7 - Suspension.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Suspension. 242.7 Section 242.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE COMMERCIAL FISHING ON RED LAKE INDIAN RESERVATION § 242.7 Suspension. All commercial fishing operations may be suspended by order of the Secretary at...

  9. 12 CFR 19.242 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Definitions. 19.242 Section 19.242 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Removal, Suspension, and Debarment of Accountants From Performing Audit Services § 19.242 Definitions. As used in...

  10. 32 CFR 242a.3 - Open meetings.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Open meetings. 242a.3 Section 242a.3 National... PUBLIC MEETING PROCEDURES OF THE BOARD OF REGENTS, UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES § 242a.3 Open meetings. (a) Members shall not jointly conduct or dispose of business of the Board...

  11. 32 CFR 242a.8 - Effective date.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Effective date. 242a.8 Section 242a.8 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... § 242a.8 Effective date. This part shall become effective on March 12, 1977....

  12. Apparatus for the measurement of total body nitrogen using prompt neutron activation analysis with californium-252.

    Science.gov (United States)

    Mackie, A; Hannan, W J; Smith, M A; Tothill, P

    1988-01-01

    Details of clinical apparatus designed for the measurement of total body nitrogen (as an indicator of body protein), suitable for the critically ill, intensive-care patient are presented. Californium-252 radio-isotopic neutron sources are used, enabling a nitrogen measurement by prompt neutron activation analysis to be made in 40 min with a precision of +/- 3.2% for a whole body dose equivalent of 0.145 mSv. The advantages of Californium-252 over alternative neutron sources are discussed. A comparison between two irradiation/detection geometries is made, leading to an explanation of the geometry adopted for the apparatus. The choice of construction and shielding materials to reduce the count rate at the detectors and consequently to reduce the pile-up contribution to the nitrogen background is discussed. Salient features of the gamma ray spectroscopy system to reduce spectral distortion from pulse pile-up are presented.

  13. Dicty_cDB: AFG242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ycdb.biol.tsukuba.ac.jp/CSM/AF/AFG2-B/AFG242Q.Seq.d/ Representative seq. ID AFG24...2F (Link to Original site) Representative DNA sequence >AFG242 (AFG242Q) /CSM/AF/AFG2-B/AFG242Q.Seq.d/ AATTT

  14. 42 CFR 24.2 - Allocation.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Allocation. 24.2 Section 24.2 Public Health PUBLIC....2 Allocation. (a) The Secretary, within the number authorized in the PHS Act, shall determine the... may advise the Secretary to make adjustments to the allocation at any time. (c) The majority of...

  15. 24 CFR 242.61 - Management.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Management. 242.61 Section 242.61... Management. The mortgagor shall provide for management of the hospital in a manner satisfactory to HUD. (a) Contract Management of Hospital. The mortgagor shall not execute a management agreement or any...

  16. 48 CFR 242.7301 - General.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false General. 242.7301 Section 242.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contractor Insurance/Pension...

  17. 24 CFR 242.82 - Energy conservation.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Energy conservation. 242.82 Section... INSURANCE FOR HOSPITALS Miscellaneous Requirements § 242.82 Energy conservation. Construction, mechanical equipment, and energy and metering selections shall provide cost-effective energy conservation in...

  18. Spontaneous Partitioning of Californium from Curium: Curious Cases from the Crystallization of Curium Coordination Complexes

    Energy Technology Data Exchange (ETDEWEB)

    Cary, Samantha K.; Silver, Mark A.; Liu, Guokui; Wang, Jamie C.; Bogart, Justin A.; Stritzinger, Jared T.; Arico, Alexandra A.; Hanson, Kenneth; Schelter, Eric J.; Albrecht-Schmitt, Thomas E.

    2015-12-07

    The reaction of 248CmCl3 with excess 2,6-pyridinedicarboxylic acid (DPA) under mild solvothermal conditions results in crystallization of the tris-chelate complex Cm(HDPA)3·H2O. Approximately half of the curium remains in solution at the end of this process, and evaporation of the mother liquor results in crystallization of the bis-chelate complex [Cm(HDPA)- (H2DPA)(H2O)2Cl]Cl·2H2O. 248Cm is the daughter of the α decay of 252Cf and is extracted in high purity from this parent. However, trace amounts of 249,250,251Cf are still present in all samples of 248Cm. During the crystallization of Cm(HDPA)3·H2O and [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl·2H2O, californium(III) spontaneously separates itself from the curium complexes and is found doped within crystals of DPA in the form of Cf(HDPA)3. These results add to the growing body of evidence that the chemistry of californium is fundamentally different from that of earlier actinides.

  19. Dicty_cDB: SLC242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Dictyostelium discoideum cDNA clone:ddc24n06, 5' ... 706 0.0 1 ( AU060920 ) Dictyostelium discoideum slug cDNA, clone SLC2...SL (Link to library) SLC242 (Link to dictyBase) - - - Contig-U12013-1 SLC242E (Link to Original site) SLC2...42F 595 SLC242Z 606 SLC242P 1201 SLC242E 751 Show SLC242 Library SL (Link to library) Clone ID SLC2...inal site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLC2-B/SLC242Q.Seq.d/ Representative seq. ID SLC2...42E (Link to Original site) Representative DNA sequence >SLC242 (SLC242Q) /CSM/SL/SLC2-B/SLC2

  20. 17 CFR 242.406 - Undermargined accounts.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Customer Margin Requirements for Security Futures § 242.406 Undermargined accounts. (a) Failure to satisfy margin call. If...

  1. 32 CFR 242b.3 - Notice.

    Science.gov (United States)

    2010-07-01

    ... SCIENCES § 242b.3 Notice. (a) Notice of all meetings of the Board shall be sent by the Secretary to each...-four hours before the meeting, shall be sufficient notice of any meeting. The recital by the Secretary...) Public announcement of meetings shall conform to the Public Meeting Procedures of the Board of...

  2. 17 CFR 242.201 - Price test.

    Science.gov (United States)

    2010-04-01

    ... M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Sho... convenience of the user, the revised text is set forth as follows: § 242.201 Circuit breaker. (a) Definitions... security is by a market maker to offset customer odd-lot orders or to liquidate an odd-lot position...

  3. 32 CFR 242b.2 - Meetings of the Board.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Meetings of the Board. 242b.2 Section 242b.2... THE HEALTH SCIENCES § 242b.2 Meetings of the Board. (a) Regular meetings. (1) The Board shall hold at... determined by the Board, meetings shall be held at the offices of the University, 4301 Jones Bridge...

  4. 42 CFR 438.242 - Health information systems.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Health information systems. 438.242 Section 438.242... Measurement and Improvement Standards § 438.242 Health information systems. (a) General rule. The State must ensure, through its contracts, that each MCO and PIHP maintains a health information system that...

  5. 24 CFR 242.63 - Additional indebtedness and leasing.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Additional indebtedness and leasing. 242.63 Section 242.63 Housing and Urban Development Regulations Relating to Housing and Urban... Requirements § 242.63 Additional indebtedness and leasing. The mortgagor shall not enter into any...

  6. 25 CFR 242.12 - Authority to lease.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Authority to lease. 242.12 Section 242.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE COMMERCIAL FISHING ON RED LAKE INDIAN RESERVATION § 242.12 Authority to lease. The Band, with the approval of the Secretary, may execute a lease...

  7. 7 CFR 1220.242 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1220.242 Section 1220.242... CONSUMER INFORMATION Soybean Promotion and Research Order Reports, Books, and Records § 1220.242 Books and... subpart shall maintain and make available for inspection by the Board or Secretary such books and...

  8. 25 CFR 242.5 - Disposition of unmarketable fish.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Disposition of unmarketable fish. 242.5 Section 242.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE COMMERCIAL FISHING ON RED LAKE INDIAN RESERVATION § 242.5 Disposition of unmarketable fish. All unmarketable live fish...

  9. 36 CFR 242.12 - Local advisory committees.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Local advisory committees. 242.12 Section 242.12 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE..., the particular Regional Council in carrying out its function as set forth in § 242.11. (b)...

  10. 17 CFR 242.301 - Requirements for alternative trading systems.

    Science.gov (United States)

    2010-04-01

    ... trading systems. 242.301 Section 242.301 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... FUTURES Regulation Ats-Alternative Trading Systems § 242.301 Requirements for alternative trading systems. (a) Scope of section. An alternative trading system shall comply with the requirements in...

  11. Dicty_cDB: CFH242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFH242 (Link to dictyBase) - - - Contig-U16349-1 CFH242Z (Link... to Original site) - - CFH242Z 650 - - - - Show CFH242 Library CF (Link to library) Clone ID CFH242 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16349-1 Original site URL http://dict...d Amino Acid sequence ---ASGSVVEQCSSVDSISNLPTTMQLFAGIKSICTEMAMDGCEKCSGNSPTTTCDVLPV YSSLCMAMPDMSQCANWTKMCSSSG...*fn*fiflk wflskill*ryn*rmftcyrtnm*lcfnaccndi*cctl Frame C: ---ASGSVVEQCSSVDSISNLPTTMQLFAGIKSICT

  12. Clinical Report on Californium-252 Neutron Intraluminal Brachytherapy Combined with External Irradiation for Cervical Carcinoma Treatment

    Institute of Scientific and Technical Information of China (English)

    Huanyu Zhao; Keming Wang; Jian Sun; Xin Geng; Weiming Zhang

    2006-01-01

    OBJECTIVE To observe the curative effects and complications of californium-252 (252Cf) neutron intraluminal brachytherapy (IBT) combined with external irradiation (El) for treatment of cervical carcinoma.METHODS From December 2000 to December 2004, 128 cases of cervical carcinoma staged into ⅡA~ⅢB according to the International Federation of Gynecology and Obstetrics (FIGO) standards were treated with 252Cf neutron IBT using 8~10 Gy per fraction, once a week. The total dose at reference A point was 36~40 Gy in 4~5 fractions. From the second day after 252Cf neutron IBT treatment, the whole pelvic cavity was treated with 60Co γ-ray El, applying 2 Gy per fraction, 4 times per week. After 20~25 Gy of El, the center of the whole pelvic field was blocked with 4 cm of lead in width. The total dose of El was 45~50 Gy.RESULTS The short-term therapeutic effects were CR 95.3% and PR 4.7%. The 3 and 5-year local control rates were 93.5% and 87.9%. The overall 3-year survival rate was 87.5% and for Stages Ⅱ and Ⅲ , 90.9%and 81.5% respectively; the overall 5-year survival rate was 70% and for Stages Ⅱ and Ⅲ, 76.2% and 61% respectively. The rate of radiation complications was 4.7% for radiation cystitis, 7.8% for radiation proctitis, 6.3%for vagina contracture and adhesion and 5.5% for protracted radiation proctitis.CONCLUSION An combination of 252Cf neutron IBT with El for treatment of cervical carcinoma can be well-tolerated by cervical carcinoma patients. The rate of local tumor control is high and radiation complications are few.

  13. Application of TSH bioindicator for studying the biological efficiency of neutrons from californium-252 source

    Energy Technology Data Exchange (ETDEWEB)

    Cebulska-Wasilewska, A.; Rekas, K. [Institute of Nuclear Physics, Cracow (Poland); Kim, J.K. [Korea Atomic Energy Research Inst., Taejon (Korea, Republic of)

    1997-12-31

    The effectiveness of neutrons from a Californium-252 source in the induction of various abnormalities in the Tradescantia clone 4430 stamen hair cells (TSH-assay) was studied. The special attention was paid to check whether any enhancement in effects caused by process of boron neutron capture is visible in the cells enriched with boron ions. Two chemicals (borax and BSH) were applied to introduce boron-10 ions into cells. Inflorescence, normal or pretreated with chemicals containing boron, were irradiated in the air with neutrons from a Cf-252 source at KAERI, Taejon, Korea. To estimate the relative biological effectiveness (RBE) in the induction of gene mutations of the neutron beam under the study, Tradescantia inflorescences, without any chemical pretreatment, were irradiated with various doses of X-rays. The ranges of radiation doses used were 0-0.1 Gy in neutrons and 0-0.5 Gy in X-rays. After the time needed to complete the postirradiation repair Tradescantia cuttings were transferred to Cracow, where screening of gene and lethal; mutations, cell cycle alterations in somatic cells have been done, and dose response relationships were figured. The maximal RBE values were estimated in the range of 4.6-6.8. Alterations of RBE value were observed; from 6.8 to 7.8 in the case of plants pretreated with 240 ppm of B-10 from borax, and 4.6 to 6.1 in the case of 400 ppm of B-10 from BSH. Results showed a slight, although statistically insignificant increase in biological efficacy of radiation from the Cf-252 source in samples pretreated with boron containing chemicals. (author)

  14. Calibration of 242 Pu Tracer by Mass Spectrometry%质谱法标定242 Pu指示剂

    Institute of Scientific and Technical Information of China (English)

    李冬梅; 徐江; 杜丽丽

    2014-01-01

    将高纯242 Pu浓度标准溶液与239 Pu混合,质谱法测量R239/242(A)先标定四水硫酸钚中239 Pu的浓度;再将四水硫酸钚与待标定的242 Pu指示剂混合,测量R239/242(A),标定242 Pu 指示剂的浓度。质谱测量还可标定得到242 Pu指示剂中的钚同位素丰度。采用两次同位素稀释质谱法标定242 Pu 指示剂快捷简便,可在2日内完成。测量精度高,242 Pu浓度的相对合成标准不确定度为0.75%,该指示剂可满足高精度分析工作的需求。%242 Pu is commonly employed as tracer for determination of 239 Pu in environmental samples.The 239 Pu concentration in Pu(SO4 )2 ·4H2 O solution was determined by isotope dilution-mass spectrometry (ID-MS)using a high pure 242 Pu spike.Then the 242 Pu tracer in our laboratary was calibrated by ID-MS using the calibrated 239 Pu solution as spike.By meas-uring the atom ratio of 239 Pu to 242 Pu twice by ID-MS,the concentration and abundance of the 242 Pu tracer in laboratary were finally calibrated.This method was proved to be efficient with high precision.The process could be finished within two days with an uncertainty of 0.75%. The calibrated 242 Pu tracer in laboratory could meet the demand of high-precision analysis.

  15. Study of the shielding for spontaneous fission sources of Californium-252; Estudio de blindaje para fuentes de fision espontanea de Californio-252

    Energy Technology Data Exchange (ETDEWEB)

    Davila R, I

    1991-06-15

    A shielding study is made to attenuate, until maximum permissible levels, the neutrons radiation and photons emitted by spontaneous fission coming from a source of Californium-252. The compound package by a database (Library DLC-23) and the ANISNW code is used, in it version for personal computer. (Author)

  16. 242-A evaporator safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    CAMPBELL, T.A.

    1999-05-17

    This report provides a revised safety analysis for the upgraded 242-A Evaporator (the Evaporator). This safety analysis report (SAR) supports the operation of the Evaporator following life extension upgrades and other facility and operations upgrades (e.g., Project B-534) that were undertaken to enhance the capabilities of the Evaporator. The Evaporator has been classified as a moderate-hazard facility (Johnson 1990). The information contained in this SAR is based on information provided by 242-A Evaporator Operations, Westinghouse Hanford Company, site maintenance and operations contractor from June 1987 to October 1996, and the existing operating contractor, Waste Management Hanford (WMH) policies. Where appropriate, a discussion address the US Department of Energy (DOE) Orders applicable to a topic is provided. Operation of the facility will be compared to the operating contractor procedures using appropriate audits and appraisals. The following subsections provide introductory and background information, including a general description of the Evaporator facility and process, a description of the scope of this SAR revision,a nd a description of the basic changes made to the original SAR.

  17. 24 CFR 242.72 - Leasing of hospital.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Leasing of hospital. 242.72 Section... INSURANCE FOR HOSPITALS Miscellaneous Requirements § 242.72 Leasing of hospital. Leasing of a hospital in its entirety is prohibited. Notwithstanding this prohibition, any proposal in which leasing of...

  18. 40 CFR 61.242-7 - Standards: Valves.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standards: Valves. 61.242-7 Section 61... (Fugitive Emission Sources) § 61.242-7 Standards: Valves. (a) Each valve shall be monitored monthly to...) If an instrument reading of 10,000 ppm or greater is measured, a leak is detected. (c)(1) Any...

  19. 10 CFR 431.242 - Test Procedures [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Test Procedures 431.242 Section 431.242 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL... upstream of the draft control device of an individual, automatically operated, fossil fuel-fired...

  20. 40 CFR 61.242-10 - Standards: Delay of repair.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standards: Delay of repair. 61.242-10... Leaks (Fugitive Emission Sources) § 61.242-10 Standards: Delay of repair. (a) Delay of repair of equipment for which leaks have been detected will be allowed if repair within 15 days is...

  1. 40 CFR 61.242-2 - Standards: Pumps.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standards: Pumps. 61.242-2 Section 61... (Fugitive Emission Sources) § 61.242-2 Standards: Pumps. (a)(1) Each pump shall be monitored monthly to... (d), (e), (f) and (g) of this section. (2) Each pump shall be checked by visual inspection...

  2. 17 CFR 242.204 - Close-out requirement.

    Science.gov (United States)

    2010-04-01

    ... 600(b)(64) of Regulation NMS (17 CFR 242.600(b)(64)). Regulation ATS—Alternative Trading Systems...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation...

  3. 17 CFR 242.302 - Recordkeeping requirements for alternative trading systems.

    Science.gov (United States)

    2010-04-01

    ... alternative trading systems. 242.302 Section 242.302 Commodity and Securities Exchanges SECURITIES AND... SECURITY FUTURES Regulation Ats-Alternative Trading Systems § 242.302 Recordkeeping requirements for alternative trading systems. To comply with the condition set forth in paragraph (b)(8) of § 242.301,...

  4. Long-term effects of an intracavitary treatment with californium-252 on normal tissue. [Swine, /sup 226/Ra

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, M.F.; Beamer, J.L.; Mahony, T.D.; Cross, F.T.; Lund, J.E.; Endres, G.W.R.

    1976-01-01

    About one hundred fifty swine were exposed to either radium-226 or californium-252 sources in the uterine cervix to determine an RBE for both acute and long-term effects. That value for early changes in the tissues at risk in the treatment of cervical cancer was between 6.2 and 6.8. The incidence of complications increased with time after exposure, especially among animals treated with /sup 252/Cf. Analysis of rectal injury showed that ulceration occurred frequently within a year postexposure at doses between 1600 and 2400 rad calculated at 2 cm lateral to the source midline. Fat necrosis and smooth muscle atrophy, resulting in a local rectal stricture, were delayed changes observed in some animals. The lower ureter was the site for a greater frequency of complications than the GI tract. Ureteral stricture often occurred at doses of 1200 rad from /sup 252/Cf and 7000 rad from /sup 226/Ra. Observation of delayed effects in the uterine-cervix in animals held up to 4 years postexposure indicate that the RBE for /sup 252/Cf may be increased to a value as high as 18, while repair may have even decreased it to about 5.6 in the rectum. Fifty swine are still being observed for long-term effects after doses above 800 rad from /sup 252/Cf and 5000 rad from /sup 226/Ra.

  5. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev, S.; Dickerson, C.; Levand, A.; Ostroumov, P. N.; Pardo, R. C.; Savard, G.; Vondrasek, R. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Alessi, J.; Beebe, E.; Pikin, A. [Collider-Accelerator Department, Brookhaven National Laboratory, Upton, New York 11973 (United States); Kuznetsov, G. I.; Batazova, M. A. [Budker Institute of Nuclear Physics, Novosibirsk 630090 (Russian Federation)

    2012-02-15

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  6. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev S.; Alessi J.; Dickerson, C.; Levand, A.; Ostroumov, P.N.; Pardo, R.C.; Savard, G.; Vondrasek, R.; Beebe, E.; Pikin, A.; Kuznetsov, G.I.; Batazova, M.A.

    2012-02-03

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  7. 17 CFR 242.405 - Withdrawal of margin.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Customer Margin Requirements for Security Futures § 242.405 Withdrawal of margin. (a) By the customer. Except as otherwise... account after such withdrawal is sufficient to satisfy the required margin for the security futures...

  8. 24 CFR 242.58 - Books, accounts, and financial statements.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Books, accounts, and financial... Requirements § 242.58 Books, accounts, and financial statements. (a) Books and accounts. The mortgagor's books... Agreement. (f) Books of management agents. The books and records of management agents, lessees,...

  9. 24 CFR 242.78 - Zoning, deed, and building restrictions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Zoning, deed, and building... AUTHORITIES MORTGAGE INSURANCE FOR HOSPITALS Miscellaneous Requirements § 242.78 Zoning, deed, and building restrictions. The project when completed shall not violate any material zoning or deed restrictions...

  10. 24 CFR 242.45 - Early commencement of work.

    Science.gov (United States)

    2010-04-01

    ... would suffer from waiting. (2) A plan detailing how the hospital will finance the limited construction... MORTGAGE INSURANCE FOR HOSPITALS Construction § 242.45 Early commencement of work. (a) Site preparation... to the issuance of a commitment or denial by HUD, the hospital and lender may request for good...

  11. 17 CFR 242.504 - Notification to associated persons.

    Science.gov (United States)

    2010-04-01

    ... Regulation Ac-Analyst Certification § 242.504 Notification to associated persons. A broker or dealer shall notify any person with whom that broker or dealer is associated who publishes, circulates, or provides research reports: (a) Whether the broker or dealer maintains and enforces written policies and...

  12. 17 CFR 242.607 - Customer account statements.

    Science.gov (United States)

    2010-04-01

    ... or dealer's policies regarding receipt of payment for order flow from any broker or dealer, national... Regulation Nms-Regulation of the National Market System § 242.607 Customer account statements. (a) No broker... in section 17B of the Act (15 U.S.C. 78q-2), unless such broker or dealer informs such customer,...

  13. 17 CFR 242.600 - NMS security designation and definitions.

    Science.gov (United States)

    2010-04-01

    ... transaction reporting plan approved by the Commission pursuant to § 242.601. (23) Electronic communications... orders to be executed against in whole or in part; except that the term electronic communications network..., dealers, or investors on a real-time or other current and continuing basis, whether through an...

  14. 48 CFR 2452.242-71 - Contract management system.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract management system... 2452.242-71 Contract management system. As prescribed in 2442.1107, insert the following clause: Contract Management System (FEB 2006) (a) The contractor shall use contract management baseline...

  15. 17 CFR 242.606 - Disclosure of order routing information.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the National Market System § 242.606 Disclosure of order routing information. (a... calendar quarter a report on its routing of non-directed orders in NMS securities during that quarter....

  16. 17 CFR 242.605 - Disclosure of order execution information.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the National Market System § 242.605 Disclosure of order execution information... covered orders in NMS stocks that it received for execution from any person. Such report shall be...

  17. 40 CFR 98.242 - GHGs to report.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.242 GHGs to report. You must report the information in paragraphs (a) through (c) of this section: (a) CO2 CH4, and N2O process emissions from each...

  18. 48 CFR 1252.242-70 - Dissemination of information-educational institutions.

    Science.gov (United States)

    2010-10-01

    ... information-educational institutions. 1252.242-70 Section 1252.242-70 Federal Acquisition Regulations System... Provisions and Clauses 1252.242-70 Dissemination of information—educational institutions. As prescribed in (TAR) 48 CFR 1242.7000(a), insert the following clause: Dissemination of...

  19. 40 CFR 81.242 - Pecos-Permian Basin Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Air Quality Control Regions § 81.242 Pecos-Permian Basin Intrastate Air Quality Control Region. The Pecos-Permian Basin Intrastate Air Quality Control Region (New Mexico) consists of the territorial area... Quality Control Region. 81.242 Section 81.242 Protection of Environment ENVIRONMENTAL PROTECTION...

  20. 19 CFR 24.2 - Persons authorized to receive Customs collections.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Persons authorized to receive Customs collections. 24.2 Section 24.2 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.2 Persons authorized to...

  1. 48 CFR 242.771 - Independent research and development and bid and proposal costs.

    Science.gov (United States)

    2010-10-01

    ... SERVICES Indirect Cost Rates 242.771 Independent research and development and bid and proposal costs. ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Independent research and development and bid and proposal costs. 242.771 Section 242.771 Federal Acquisition Regulations System...

  2. 17 CFR 242.602 - Dissemination of quotations in NMS securities.

    Science.gov (United States)

    2010-04-01

    ... NMS securities. 242.602 Section 242.602 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the National Market System § 242.602 Dissemination of quotations...

  3. 46 CFR 308.306 - Second Seamen's War Risk Policy, Form MA-242.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Second Seamen's War Risk Policy, Form MA-242. 308.306... RISK INSURANCE Second Seamen's War Risk Insurance § 308.306 Second Seamen's War Risk Policy, Form MA-242. (a) The standard form of Second Seamen's War Risk Policy Form MA-242, may be obtained from...

  4. 17 CFR 242.102 - Activities by issuers and selling security holders during a distribution.

    Science.gov (United States)

    2010-04-01

    ... selling security holders during a distribution. 242.102 Section 242.102 Commodity and Securities Exchanges... REQUIREMENTS FOR SECURITY FUTURES Regulation M § 242.102 Activities by issuers and selling security holders... or on behalf of an issuer or selling security holder, it shall be unlawful for such person, or...

  5. 48 CFR 252.242-7004 - Material management and accounting system.

    Science.gov (United States)

    2010-10-01

    ..., inventory, accounting, or other systems. (2) Valid time-phased requirements means material that is— (i... accounting system. 252.242-7004 Section 252.242-7004 Federal Acquisition Regulations System DEFENSE... CLAUSES Text of Provisions And Clauses 252.242-7004 Material management and accounting system....

  6. 17 CFR 242.303 - Record preservation requirements for alternative trading systems.

    Science.gov (United States)

    2010-04-01

    ... requirements for alternative trading systems. 242.303 Section 242.303 Commodity and Securities Exchanges... REQUIREMENTS FOR SECURITY FUTURES Regulation Ats-Alternative Trading Systems § 242.303 Record preservation requirements for alternative trading systems. (a) To comply with the condition set forth in paragraph (b)(9)...

  7. CO observations of high-z radio galaxies MRC 2104-242 and MRC 0943-242 : spectral-line performance of the Compact Array Broadband Backend

    NARCIS (Netherlands)

    Emonts, B. H. C.; Norris, R. P.; Feain, I.; Miley, G.; Sadler, E. M.; Villar-Martin, M.; Mao, M. Y.; Oosterloo, T. A.; Ekers, R. D.; Stevens, J. B.; Wieringa, M. H.; Coppin, K. E. K.; Tadhunter, C. N.

    2011-01-01

    We present the first 7-mm observations of two high-redshift, Ly alpha-bright radio galaxies (MRC 2104-242 and MRC 0943-242) performed with the 2 x 2 GHz instantaneous bandwidth of the Compact Array Broadband Backend (CABB) at the Australia Telescope Compact Array (ATCA). The aim was to search for (C

  8. 242-A Control System device logic software documentation. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Berger, J.F.

    1995-05-19

    A Distributive Process Control system was purchased by Project B-534. This computer-based control system, called the Monitor and Control System (MCS), was installed in the 242-A Evaporator located in the 200 East Area. The purpose of the MCS is to monitor and control the Evaporator and Monitor a number of alarms and other signals from various Tank Farm facilities. Applications software for the MCS was developed by the Waste Treatment System Engineering Group of Westinghouse. This document describes the Device Logic for this system.

  9. 242A Distributed Control System Year 2000 Acceptance Test Report

    Energy Technology Data Exchange (ETDEWEB)

    TEATS, M.C.

    1999-08-31

    This report documents acceptance test results for the 242-A Evaporator distributive control system upgrade to D/3 version 9.0-2 for year 2000 compliance. This report documents the test results obtained by acceptance testing as directed by procedure HNF-2695. This verification procedure will document the initial testing and evaluation of the potential 242-A Distributed Control System (DCS) operating difficulties across the year 2000 boundary and the calendar adjustments needed for the leap year. Baseline system performance data will be recorded using current, as-is operating system software. Data will also be collected for operating system software that has been modified to correct year 2000 problems. This verification procedure is intended to be generic such that it may be performed on any D/3{trademark} (GSE Process Solutions, Inc.) distributed control system that runs with the VMSTM (Digital Equipment Corporation) operating system. This test may be run on simulation or production systems depending upon facility status. On production systems, DCS outages will occur nine times throughout performance of the test. These outages are expected to last about 10 minutes each.

  10. Consistent Data Assimilation of Isotopes: 242Pu and 105Pd

    Energy Technology Data Exchange (ETDEWEB)

    G. Palmiotti; H. Hiruta; M. Salvatores

    2012-09-01

    In this annual report we illustrate the methodology of the consistent data assimilation that allows to use the information coming from integral experiments for improving the basic nuclear parameters used in cross section evaluation. A series of integral experiments are analyzed using the EMPIRE evaluated files for 242Pu and 105Pd. In particular irradiation experiments (PROFIL-1 and -2, TRAPU-1, -2 and -3) provide information about capture cross sections, and a critical configuration, COSMO, where fission spectral indexes were measured, provides information about fission cross section. The observed discrepancies between calculated and experimental results are used in conjunction with the computed sensitivity coefficients and covariance matrix for nuclear parameters in a consistent data assimilation. The results obtained by the consistent data assimilation indicate that not so large modifications on some key identified nuclear parameters allow to obtain reasonable C/E. However, for some parameters such variations are outside the range of 1 s of their initial standard deviation. This can indicate a possible conflict between differential measurements (used to calculate the initial standard deviations) and the integral measurements used in the statistical data adjustment. Moreover, an inconsistency between the C/E of two sets of irradiation experiments (PROFIL and TRAPU) is observed for 242Pu. This is the end of this project funded by the Nuclear Physics Program of the DOE Office of Science. We can indicate that a proof of principle has been demonstrated for a few isotopes for this innovative methodology. However, we are still far from having explored all the possibilities and made this methodology to be considered proved and robust. In particular many issues are worth further investigation: • Non-linear effects • Flexibility of nuclear parameters in describing cross sections • Multi-isotope consistent assimilation • Consistency between differential and integral

  11. Organic emission calculations for the 242-A evaporator vessel vent system

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, M.R.

    1996-06-20

    This document contains historical calculations originally published in the 242-A Evaporator Dangerous Waste Permit Application, DOE/RL-90-42, Rev 0. They are being released as a supporting document, along with brief explanatory information, to be used as a reference in Rev 1 of the permit application and in other supporting documents, such as the 242-A Evaporator Data Quality Objectives.

  12. 242-A MCS Logic Acceptance Test Report for Year 2000 Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    TEATS, M.C.

    1999-08-31

    242-A Evaporator distributive control system upgrade to D/3 version 9.0-2 for year 2000 compliance. Testing was performed per test procedure HNF-3568. There were no unresolved exceptions. The system responded correctly to all testing and meets the requirements to operate the 242-A This report documents the acceptance test results for the Evaporator facility.

  13. 24 CFR 242.81 - Lead-based paint poisoning prevention.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Lead-based paint poisoning prevention. 242.81 Section 242.81 Housing and Urban Development Regulations Relating to Housing and Urban... prevention. Requirements set forth in 24 CFR part 35 apply to this program....

  14. 38 CFR 17.242 - Coordination of programs with Department of Health and Human Services.

    Science.gov (United States)

    2010-07-01

    ... specialized medical resources or medical information services shall be coordinated to a maximum extent... jurisdiction of the Department of Health and Human Services. Grants for Exchange of Information ... with Department of Health and Human Services. 17.242 Section 17.242 Pensions, Bonuses, and...

  15. 48 CFR 53.242-1 - Novation and change-of-name agreements (SF 30).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Novation and change-of-name agreements (SF 30). 53.242-1 Section 53.242-1 Federal Acquisition Regulations System FEDERAL...-of-name agreements (SF 30). SF 30, Amendment of Solicitation/Modification of Contract. SF...

  16. 36 CFR 242.6 - Licenses, permits, harvest tickets, tags, and reports.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Licenses, permits, harvest tickets, tags, and reports. 242.6 Section 242.6 Parks, Forests, and Public Property FOREST SERVICE... permits (Federal Subsistence Registration Permit or Federal Designated Harvester Permit) required...

  17. In vitro evaluation of the antimicrobial activity of HM-242, a novel antiseptic compound.

    Science.gov (United States)

    Okunishi, Junji; Nishihara, Yutaka; Maeda, Shirou; Ikeda, Masahiro

    2009-09-01

    The antimicrobial activities of N(4)-octyl-6,6-dimethyl-N(2)-(4-methylbenzyl)-1,6-dihydro-1,3,5-triazine-2,4-diamine (HM-242), a novel synthetic compound, were compared with those of chlorhexidine gluconate (CHG). HM-242 was a more potent microbicide than CHG in vitro; however, its minimal inhibitory concentrations were similar. In particular, HM-242 killed various Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, both efficiently and rapidly. HM-242 also showed potent virucidal activity against enveloped viruses such as influenza virus and herpes simplex virus. These characteristics suggest that HM-242 may well be useful as an antiseptic.

  18. 27 CFR 24.242 - Authority to use greater quantities of decolorizing material in juice or wine.

    Science.gov (United States)

    2010-04-01

    ... quantities of decolorizing material in juice or wine. 24.242 Section 24.242 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Storage, Treatment and Finishing of Wine § 24.242 Authority to use greater quantities of decolorizing material...

  19. Waste volume reduction factors for potential 242-A evaporator feed

    Energy Technology Data Exchange (ETDEWEB)

    Sederburg, J.P.

    1995-05-04

    Double-shell tank (DST) storage space requirements have been shown to be highly dependent on the end point of 242-A operations. Consequences to the DST of various waste volumes, and concentrations, are evaluated. Only waste streams that are currently planned to be stored in the DST system before the year 2004 are discussed. As of January 1, 1995, approximately 27-million L (7.2-million gal) of dilute wastes are stored in the DSTs available for evaporator processing. Waste streams planned to be transferred to the DSTs before December 31, 2004, are identified. The DST volume for storing slurry from these wastes is presented in this document. At a final slurry specific gravity of -1.35, 22.5-million L (5.93-million gal) of DST space would be needed on December 31, 2004, to store the product from evaporator processing of these feedstocks. The expected volume needed if the resultant slurry were concentrated to the traditional double-shell slurry feed (DSSF) phase boundary (a specific gravity of {approximately}1.5) would be 17.7-million L (4.67-million gal). An additional 4.8-million L (1.26-million gal) is therefore needed if these wastes are concentrated to a specific gravity of 1.35 instead of the DSSF limit.

  20. 29 CFR 779.242 - Goods that “have been moved in” commerce.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Goods that âhave been moved inâ commerce. 779.242 Section... Commerce by Any Person § 779.242 Goods that “have been moved in” commerce. For the purpose of section 3(s), goods will be considered to “have been moved * * * in commerce” when they have moved across State...

  1. CO observations of high-z radio galaxies MRC 2104-242 and MRC 0943-242: spectral-line performance of the Compact Array Broadband Backend

    CERN Document Server

    Emonts, B H C; Feain, I; Miley, G; Sadler, E M; Villar-Martin, M; Mao, M Y; Oosterloo, T A; Ekers, R D; Stevens, J B; Wieringa, M H; Coppin, K E K; Tadhunter, C N

    2011-01-01

    We present the first 7-millimetre observations of two high-redshift, Lya-bright radio galaxies (MRC 2104-242 and MRC 0943-242) performed with the 2 x 2 GHz instantaneous bandwidth of the Compact Array Broadband Backend (CABB) at the Australia Telescope Compact Array (ATCA). The aim was to search for 12CO(1-0) emission in these systems and test the millimetre capabilities of CABB for performing spectral line observations at high redshifts. We show that the stable band and enhanced velocity coverage of CABB, combined with hybrid array configurations, provide the ATCA with excellent 7-mm capabilities that allow reliable searches for the ground transition of CO at high redshifts. In this paper we explicitly discuss the calibration procedures used to reach our results. We set a firm upper limit to the mass of molecular gas in MRC 2104-242 (z = 2.5) of M(H2) < 2 x 10^10 (alpha_x/0.8) M_sun. For MRC 0943-242 (z=2.9) we derive an upper limit of M(H2) < 6 x 10^10 (alpha_x/0.8) M_sun. We also find a tentative 3-s...

  2. Serum level of TSGF,CA242 and CA19-9 in pancreatic cancer

    Institute of Scientific and Technical Information of China (English)

    Jing-Ting Jiang; Chang-Ping Wu; Hai-Feng Deng; Ming-Yang Lu; Jun Wu; Hong-Yu Zhang; Wen-Hui Sun; Mei Ji

    2004-01-01

    AIM: To establish a method to detect the expression of the tumor specific growth factor TSGF, CA242 and CA19-9 in serum and evaluate their value in diagnosis of pancreatic cancer.METHODS: ELISA and Biochemical colorimetric assay were used to detect the serum content of TSGF, CA242 and CA19-9 in 200 normal cases, 52 pancreatitis patients and 96 pancreatic cancer patients.RESULTS: The positive likelihood ratios of TSGF, CA242and CA19-9 were 5.4, 12.6 and 6.3, respectively, and their negative likelihood ratios were 0.10, 0.19 and 0.17,respectively. With single tumor marker diagnosed pancreatic cancer, the highest sensitivity and specificity of TSGF were 91.6% and 93.5%. In combined test with 3 markers, when all of them were positive, the sensitivity changed to 77.0%and the specificity and the positive predictive value were 100%. The levels of TSGF and CA242 were significantly higher in the patients with pancreatic cancer of head than those in the patients with pancreatic cancer of body, tail and whole pancreas, but the expression of CA19-9 had no correlation with the positions of the pancreatic cancer. The sensitivity of TSGF, CA242 and CA19-9 was increased with the progress in stages of pancreatic cancer. In stage I, the sensitivity of TSGF was markedly higher than CA242 and CA19-9.CONCLUSION: The combined use of TSGF, CA242 and CA19-9 expressions can elevate the specificity for pancreatic cancer diagnosis. And it shows that it plays an important role to differentiate positions and tissue typing. It is a forepart diagnosis for the pancreatic cancer by combination checking.There is very important correlation between the three markers and the pancreatic cancer.

  3. Statistical properties of 243Pu, and 242Pu(n ,γ ) cross section calculation

    Science.gov (United States)

    Laplace, T. A.; Zeiser, F.; Guttormsen, M.; Larsen, A. C.; Bleuel, D. L.; Bernstein, L. A.; Goldblum, B. L.; Siem, S.; Garotte, F. L. Bello; Brown, J. A.; Campo, L. Crespo; Eriksen, T. K.; Giacoppo, F.; Görgen, A.; Hadyńska-KlÈ©k, K.; Henderson, R. A.; Klintefjord, M.; Lebois, M.; Renstrøm, T.; Rose, S. J.; Sahin, E.; Tornyi, T. G.; Tveten, G. M.; Voinov, A.; Wiedeking, M.; Wilson, J. N.; Younes, W.

    2016-01-01

    The level density and γ -ray strength function (γ SF ) of 243Pu have been measured in the quasicontinuum using the Oslo method. Excited states in 243Pu were populated using the 242Pu(d ,p ) reaction. The level density closely follows the constant-temperature level density formula for excitation energies above the pairing gap. The γ SF displays a double-humped resonance at low energy as also seen in previous investigations of actinide isotopes. The structure is interpreted as the scissors resonance and has a centroid of ωSR=2.42 (5 ) MeV and a total strength of BSR=10.1 (15 ) μN2 , which is in excellent agreement with sum-rule estimates. The measured level density and γ SF were used to calculate the 242Pu(n ,γ ) cross section in a neutron energy range for which there were previously no measured data.

  4. Neutron Induced Fission Measurements of ^242mAm at DANCE

    Science.gov (United States)

    Chyzh, A.; Wu, C. Y.; Macri, R. A.; Agvaanlusan, U.; Parker, W. E.; Wilk, P. A.; Becker, J. A.; Jandel, M.; Bredeweg, T. A.; Fowler, M. M.; Bond, E. M.; Chadwick, M. B.; Clement, R. R.; Couture, A.; O'Donnell, J. M.; Haight, R. C.; Keksis, A. L.; Reifarth, R.; Rundberg, R. S.; Ullmann, J. L.; Vieira, D.; Wilhelmy, J. B.; Wouters, J. M.

    2010-11-01

    Neutron capture and fission reactions on actinieds often present challenges in measuring each of the reaction. Fission tagging detector used along with the Detector for Advanced Neutron Capture Experiments (DANCE) provides a way to measure (n,f) and (n,γ) reactions simultaneously. DANCE was used to measure ^242mAm(n,f) reaction along with a custom made fission-tagging parallel plate avalanche counter (PPAC). The results on fission related γ-ray multiplicity distribution, the ^242mAm(n,f) cross section, and the average γ-ray energy distribution are presented.

  5. 17 CFR 242.601 - Dissemination of transaction reports and last sale data with respect to transactions in NMS stocks.

    Science.gov (United States)

    2010-04-01

    ... reports and last sale data with respect to transactions in NMS stocks. 242.601 Section 242.601 Commodity..., AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the... transactions in NMS stocks. (a) Filing and effectiveness of transaction reporting plans. (1) Every...

  6. 48 CFR 1852.242-73 - NASA contractor financial management reporting.

    Science.gov (United States)

    2010-10-01

    ... Provisions and Clauses 1852.242-73 NASA contractor financial management reporting. As prescribed in 1842.7202, insert the following clause: NASA Contractor Financial Management Reporting (NOV 2004) (a) The Contractor shall submit NASA Contractor Financial Management Reports on NASA Forms 533 in accordance with...

  7. 48 CFR 1852.242-78 - Emergency Medical Services and Evacuation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Emergency Medical Services... Provisions and Clauses 1852.242-78 Emergency Medical Services and Evacuation. As prescribed in 1842.7003, insert the following clause: Emergency Medical Services and Evacuation—April 2001 The Contractor...

  8. 24 CFR 242.48 - Insured advances for certain equipment and long lead items.

    Science.gov (United States)

    2010-04-01

    ... necessary to meet the requirements of the overall construction schedule cited in the construction contract. ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE FOR HOSPITALS Construction § 242.48 Insured advances... equipment or other construction materials for which a manufacturer, fabricator, or other source requires...

  9. Reliable determination of 237Np in environmental solid samples using 242Pu as a potential tracer

    DEFF Research Database (Denmark)

    Qiao, Jixin; Hou, Xiaolin; Roos, Per;

    2011-01-01

    onto various AG 1-type anion exchangers; suitability of 242Pu as a tracer for 237Np determination in environmental solid samples; and long-term chemical stability of tetravalent Np. Experimental results revealed that the degree of resin cross-linking has a significant influence on the separation...

  10. 17 CFR 242.608 - Filing and amendment of national market system plans.

    Science.gov (United States)

    2010-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the National Market System § 242.608 Filing and amendment of... Regulation NMS and part 240, subpart A of this chapter shall, in addition to compliance with this...

  11. 42 CFR 456.242 - UR plan requirements for medical care evaluation studies.

    Science.gov (United States)

    2010-10-01

    ...: Mental Hospitals Ur Plan: Medical Care Evaluation Studies § 456.242 UR plan requirements for medical care... medical care evaluation studies under paragraph (b)(1) of this section. (b) The UR plan must provide that... 42 Public Health 4 2010-10-01 2010-10-01 false UR plan requirements for medical care...

  12. 42 CFR 431.242 - Procedural rights of the applicant or recipient.

    Science.gov (United States)

    2010-10-01

    ... AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Fair Hearings for Applicants and Recipients Procedures § 431.242 Procedural rights of the... State or local agency or the skilled nursing facility or nursing facility at the hearing; (b)...

  13. 17 CFR 242.404 - Type, form and use of margin.

    Science.gov (United States)

    2010-04-01

    ... satisfied; and (ii) An account that is transferred from one customer to another as part of a transaction... (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Customer Margin Requirements for Security Futures § 242.404 Type, form and use of margin. (a) When...

  14. Prompt fission γ -ray spectrum characteristics from 240Pu(sf ) and 242Pu(sf )

    Science.gov (United States)

    Oberstedt, S.; Oberstedt, A.; Gatera, A.; Göök, A.; Hambsch, F.-J.; Moens, A.; Sibbens, G.; Vanleeuw, D.; Vidali, M.

    2016-05-01

    In this paper we present first results for prompt fission γ -ray spectra (PFGS) characteristics from the spontaneous fission (sf) of 240Pu and 242Pu. For 242Pu(sf ) we obtained, after proper unfolding of the detector response, an average energy per photon ɛ¯γ=(0.843 ±0.012 ) MeV, an average multiplicity M¯γ=(6.72 ±0.07 ) , and an average total γ -ray energy release per fission E¯γ ,tot = (5.66 ± 0.06) MeV. The 240Pu(sf ) emission spectrum was obtained by applying a so-called detector-response transformation function determined from the 242Pu spectrum measured in exactly the same geometry. The results are an average energy per photon ɛ¯γ=(0.80 ±0.07 ) MeV, the average multiplicity M¯γ = (8.2 ± 0.4), and an average total γ -ray energy release per fission E¯γ ,tot = (6.6 ± 0.5) MeV. The PFGS characteristics for 242Pu(sf ) are in very good agreement with those from thermal-neutron-induced fission on 241Pu and scales well with the corresponding prompt neutron multiplicity. Our results in the case of 240Pu(sf ), although drawn from a limited number of events, show a significantly enhanced average multiplicity and average total energy, but may be understood from a different fragment yield distribution in 240Pu(sf ) compared to that of 242Pu(sf ).

  15. Association of the CYBA gene C242T polymorphism with schizophrenia in Southern Chinese population%中国南方汉族人群CYBA基因C242T多态性与精神分裂症的关联

    Institute of Scientific and Technical Information of China (English)

    罗旭东; 林举达; 梁爱萍; 邹晓波; 陈武标

    2016-01-01

    Objective To investigate the potential association between the C242T polymorphism of CYBA gene and risk ,severity of schizophrenia.Methods Multiplex SNaPshot was used to determine the genotype and allele frequencies of CYBA gene C242T in 906 schizophrenic patients and 982 controls. Psychotic symptoms were evaluated in accordance with structured interview for the Positive and Negative Symptom Scale (PANSS).Results (1) There were no significant differences in genotype and allele fre-quencies for C242T polymorphism between the cases and controls (P > 0.05).(2)The C242T polymor-phism C/T and T/T carriers had higher negative symptom scores and total scores than C/C carriers (P 0.05);(2)C242T多态性位点CT+TT基因型患者PANSS量表的阴性量表分及总分高于CC基因型患者(P<0.05).结论 CYBA基因C242T多态性与中国南方汉族精神分裂症的易感性无明显关联,C242T多态性位点T突变可能会加重精神分裂症患者的阴性症状.

  16. Californium Recovery from Palladium Wire

    Energy Technology Data Exchange (ETDEWEB)

    Burns, Jon D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-08-01

    The recovery of 252Cf from palladium-252Cf cermet wires was investigated to determine the feasibility of implementing it into the cermet wire production operation at Oak Ridge National Laboratory’s Radiochemical Engineering Development Center. The dissolution of Pd wire in 8 M HNO3 and trace amounts of HCl was studied at both ambient and elevated temperatures. These studies showed that it took days to dissolve the wire at ambient temperature and only 2 hours at 60°C. Adjusting the ratio of the volume of solvent to the mass of the wire segment showed little change in the kinetics of dissolution, which ranged from 0.176 mL/mg down to 0.019 mL/mg. A successful chromatographic separation of 153Gd, a surrogate for 252Cf, from Pd was demonstrated using AG 50x8 cation exchange resin with a bed volume of 0.5 mL and an internal diameter of 0.8 cm.

  17. Analytical services: 222-S characterization of 242-A Evaporator Slurry, Campaign 94-1. Addendum 1A

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-13

    During the 242-A Evaporator`s 94-1 campaign, five process samples were collected from the slurry stream for waste characterization. The five samples were collected over a 36 day time span, respectively on May 4, May 9, May 16, May 23, and June 9, 1994. Sample collections were performed per the protocol described in 242-A Evaporator Waste Analysis Plan, WHC-SD-WM-EV-060, Rev. 3 and in 242-A Evaporator Quality Assurance Project Plan, WHC-SD-WM-QAPP-009, Rev. 0. Slurry waste was characterized chemically and radiochemically by the Westinghouse Hanford Company, 222-S Laboratory as directed.

  18. New Superheavy Element Isotopes: 242Pu(48Ca,5n)285114

    Energy Technology Data Exchange (ETDEWEB)

    Ellison, Paul A; Gregorich, Kenneth E.; Berryman, Jill S.; Bleuel, Darren L.; Clark, Roderick M.; Dragojevic, Irena; Dvorak, Jan; Fallon, Paul; Fineman-Sotomayor, Carolina; Gates, Jacklyn M.; Gothe, Oliver R.; Lee, I-Yang; Loveland, Walter D.; McLaughlin, Joseph P.; Paschalis, Stefanos; Petri, Marina-Kalliopi; Qian, Jing; Stavsetra, Liv; Wiedeking, Mathis; Nitsche, Heino

    2010-10-22

    The new, neutron-deficient, superheavy element isotope {sup 285}114 was produced in {sup 48}Ca irradiations of {sup 242}Pu targets at a center-of-target beam energy of 256 MeV (E* = 50 MeV). The {alpha} decay of {sup 285}114 was followed by the sequential {alpha} decay of four daughter nuclides, {sup 281}Cn, {sup 277}Ds, {sup 273}Hs, and {sup 269}Sg. {sup 265}Rf was observed to decay by spontaneous fission. The measured {alpha}-decay Q values were compared with those from a macroscopic-microscopic nuclear mass model to give insight into superheavy element shell effects. The {sup 242}Pu({sup 48}Ca,5n){sup 285}114 cross section was 0.6{sub -0.5}{sup +0.9} pb.

  19. Measurement of the 242Pu(n,f cross section at n_TOF

    Directory of Open Access Journals (Sweden)

    Tsinganis A.

    2014-03-01

    Full Text Available Knowledge of neutron cross sections of various plutonium isotopes and other minor actinides is crucial for the design of advanced nuclear systems. The 242Pu(n,f cross sections were measured at the CERN n_TOF facility, taking advantage of the wide energy range (from thermal to GeV and the high instantaneous flux of the neutron beam. In this work, preliminary results are presented along with a theoretical cross section calculation performed with the EMPIRE code.

  20. Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets β-catenin

    Science.gov (United States)

    Nath, Niharika; Liu, Xiaoping; Jacobs, Lloydine; Kashfi, Khosrow

    2013-01-01

    Background The Wnt/β-catenin/T cell factor (TCF) signaling pathway is important in the development of nonmelanoma skin cancers (NMSCs). Nitric-oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs) are chemopreventive agents consisting of a traditional NSAID attached to an NO-releasing moiety through a chemical spacer. Previously we showed that an aromatic spacer enhanced the potency of a particular NO-NSAID compared to an aliphatic spacer. Methods We synthesized an NO-releasing NSAID with an aromatic spacer (flurbiprofen benzyl nitrate, NBS-242), and using the human skin cancer cell line A-431, we evaluated its effects on cell kinetics, Wnt/β-catenin, cyclin D1, and caspase-3. Results NBS-242 inhibited the growth of A-431 cancer cells, being ~15-fold more potent than flurbiprofen and up to 5-fold more potent than NO-flurbiprofen with an aliphatic spacer, the half maximal inhibitory concentrations (IC50) for growth inhibition being 60 ± 4 μM, 320 ± 20 μM, and 880 ± 65 μM for NBS-242, NO-flurbiprofen, and flurbiprofen, respectively. This effect was associated with inhibition of proliferation, accumulation of cells in the G0/G1 phase of the cell cycle, and an increase in apoptotic cell population. NBS-242 cleaved β-catenin both in the cytoplasm and the nucleus of A-431 cells. NBS-242 activated caspase-3 whose activation was reflected in the cleavage of procaspase-3. To test the functional consequence of β-catenin cleavage, we determined the expression of cyclin D1, a Wnt-response gene. NBS-242 reduced cyclin D1 levels in a concentration dependent manner. Conclusion These findings establish a strong inhibitory effect of NBS-242 in A-431 human epidermoid carcinoma cells. NBS-242 modulates parameters that are important in determining cellular mass. PMID:23690679

  1. Project C-018H, 242-A Evaporator/PUREX Plant Process Condensate Treatment Facility, functional design criteria. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, N.

    1995-05-02

    This document provides the Functional Design Criteria (FDC) for Project C-018H, the 242-A Evaporator and Plutonium-Uranium Extraction (PUREX) Plant Condensate Treatment Facility (Also referred to as the 200 Area Effluent Treatment Facility [ETF]). The project will provide the facilities to treat and dispose of the 242-A Evaporator process condensate (PC), the Plutonium-Uranium Extraction (PUREX) Plant process condensate (PDD), and the PUREX Plant ammonia scrubber distillate (ASD).

  2. 242-A Evaporator/Liquid Effluent Retention Facility data quality objectives

    Energy Technology Data Exchange (ETDEWEB)

    Von Bargen, B.H.

    1994-09-29

    The purpose of data quality objectives (DQO) is to determine the most cost effective methods of gathering the essential data necessary to make decisions to support successful operation of the facility. The essential data is defined by such information as sample amount, sample location, required analyses, and how sampling and analyses are performed. Successful operation is defined as meeting the campaign objectives while operating within established requirements. This DQO document addresses that portion of the system from 242-A Evaporator candidate feed tanks through discharge of process condensate to the Liquid Effluent Retention of Facility (LERF). Later revisions will incorporate and integrate the entire system, including the Effluent Treatment Facility (ETF).

  3. [Induced labor for gravidae with low Bishop's scores (with report of 242 cases)].

    Science.gov (United States)

    Shan, J

    1990-07-01

    In planned/selective delivery, gravidae with Bishop's score 5 or below 5 are deal with lower position water sac, the aim of which is to induce regular uterine contraction and complete physiological latent period of cervical dilation. From Oct 1986 to Dec 1988, 242 cases of primiparae by this method and the latent period in physiological limit. This is a great breakthrough in induced labour for gravidae with low Bishop's scores. We found that this method is simple, effective, safe, and economic. It not only alleviates pain of the gravidae, but also helps to prevent the rise of caesarean section rate.

  4. Design of a homogeneous subcritical nuclear reactor based on thorium with a source of californium 252; Diseno de un reactor nuclear subcritico homogeneo a base de Torio con una fuente de Californio 252

    Energy Technology Data Exchange (ETDEWEB)

    Delgado H, C. E.; Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Sajo B, L., E-mail: ce_delgado89@hotmail.com [Universidad Simon Bolivar, Laboratorio de Fisica Nuclear, Apdo. 89000, 1080A Caracas (Venezuela, Bolivarian Republic of)

    2015-10-15

    Full text: One of the energy alternatives to fossil fuels which do not produce greenhouse gases is the nuclear energy. One of the drawbacks of this alternative is the generation of radioactive wastes of long half-life and its relation to the generation of nuclear materials to produce weapons of mass destruction. An option to these drawbacks of nuclear energy is to use Thorium as part of the nuclear fuel which it becomes in U{sup 233} when capturing neutrons, that is a fissile material. In this paper Monte Carlo methods were used to design a homogeneous subcritical reactor based on thorium. As neutron reflector graphite was used. The reactor core is homogeneous and is formed of 70% light water as moderator, 12% of enriched uranium UO{sub 2}(NO{sub 3}){sub 4} and 18% of thorium Th(NO{sub 3}){sub 4} as fuel. To start the nuclear fission chain reaction an isotopic source of californium 252 was used with an intensity of 4.6 x 10{sup 7} s{sup -1}. In the design the value of the effective multiplication factor, whose value turned out k{sub eff} <1 was calculated. Also, the neutron spectra at different distances from the source and the total fluence were calculated, as well as the values of the ambient dose equivalent in the periphery of the reactor. (Author)

  5. Manganese determination om minerals by activation analysis, using the californium-252 as a neutron source; Determinacao de manganes em minerios, por analise por ativacao, usando californio-252 como fonte de neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Antonio

    1976-07-01

    Neutron Activation Analysis, using a Californium-252 neutron source, has been applied for the determination of manganese in ores such as pyrolusite, rodonite (manganese silicate)' and blending used in dry-batteries The favorable nuclear properties of manganese, such as high thermal neutron cross-section for the reaction {sup 55}Mn (n.gamma){sup 56} Mn, high concentration of manganese in the matrix and short half - life of {sup 56}Mn, are an ideal combination for non-destructive analysis of manganese in ores. Samples and standards of manganese dioxide were irradiated for about 20 minutes, followed by a 4 to 15 minutes decay and counted in a single channel pulse-height discrimination using a NaI(Tl) scintillation detector. Counting time was equal to 10 minutes. The interference of nuclear reactions {sup 56}Fe(n,p){sup 56}Mn and {sup 59} Co (n, {alpha}){sup 56} were studied, as well as problems in connection with neutron shadowing during irradiation, gamma-rays attenuation during counting and influence of granulometry of samples. One sample,was also analysed by wet-chemical method (sodium bismuthate) in order to compare results. As a whole, i t was shown that the analytical method of neutron activation for manganese in ores and blending, is a method simple, rapid and with good precision and accuracy. (author)

  6. Directed mutagenesis of the strongly conserved aspartate 242 in the beta-subunit of Escherichia coli proton-ATPase.

    Science.gov (United States)

    Al-Shawi, M K; Parsonage, D; Senior, A E

    1988-12-25

    Oligonucleotide-directed mutagenesis was used to substitute Asn or Val for residue Asp-242 in the beta-subunit of Escherichia coli F1-ATPase. Asp-242 is strongly conserved in beta-subunits of F1-ATPase enzymes, in a region of sequence which shows homology with numerous nucleotide-binding proteins. By analogy with adenylate kinase (Fry, D.C., Kuby, S.A., and Mildvan, A.S. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 907-911), beta-Asp-242 of F1-ATPase might participate in catalysis through electrostatic effects on the substrate Mg2+ or through hydrogen bonding to the substrate(s); an acid-base catalytic role is also plausible. The substitutions Asn and Val were chosen to affect the charge, hydrogen-bonding ability, and hydrophobicity of residue beta-Asp-242. Both mutations significantly impaired oxidative phosphorylation rates in vivo and membrane ATPase and ATP-driven proton-pumping activities in vitro. Asn-242 was more detrimental than Val-242. Purified soluble mutant F1-ATPases had normal molecular size and subunit composition, and displayed 7% (beta-Asn-242) and 17% (beta-Val-242) of normal specific Mg-ATPase activity. The relative MgATPase activities of both mutant enzymes showed similar pH dependence to normal. Relative MgATPase and CaATPase activities of normal and mutant enzymes were compared at widely varied pMg and pCa. The mutations had little effect on KM MgATP, but KM CaATP was reduced. The data showed that the carboxyl side-chain of beta-Asp-242 is not involved in catalysis either as a general acid-base catalyst or through direct involvement in any protonation/deprotonation-linked mechanism, nor is it likely to be directly involved in liganding to substrate Mg2+ during the reaction. Specificity constants (kcat/KM) for MgATP and CaATP were reduced in both mutant enzymes, showing that the mutations destabilized interactions between the catalytic nucleotide-binding domain and the transition state.

  7. The diagnostic value of joint detection of serum CA19-9, CA125 and CA242 for cholangiocarcinoma

    Institute of Scientific and Technical Information of China (English)

    Cui Da-Peng; Han Lei; Liu Zhen-Xian; Yang He; Zhang Ying-Chun

    2016-01-01

    Objective:To study the diagnostic value of joint detection of serum CA19-9, CA125 and CA242 for cholangiocarcinoma.Methods:A total of 35 patients with cholangiocarcinoma who received surgical resection in our hospital were selected as malignant group, 30 patients with cholelithiasis who received surgical resection in our hospital during the same period were selected as benign group, serum samples were collected before surgery to determine CA19-9, CA125 and CA242 content, and cholangiocarcinoma tissue and normal bile duct tissue were collected after surgery to determine the content of proliferation and invasion molecules. Results:Serum CA19-9, CA125 and CA242 levels of malignant group were significantly higher than those of control group; PROX-1, Ki-67, Bcl-2, Bad, Gab1, LOXL2, TRPM7 and CXCL12 levels in cholangiocarcinoma tissue were higher than those in benign bile duct tissue, and E-cadherin level was lower than that in benign bile duct tissue; serum CA19-9, CA125 and CA242 levels were positively correlated with PROX-1, Ki-67, Bcl-2, Bad, Gab1, LOXL2, TRPM7 and CXCL12 levels, and negatively correlated with E-cadherin level.Conclusion:Joint detection of serum CA19-9, CA125 and CA242 can not only provide reference for the diagnosis of cholangiocarcinoma, but can also provide basis for the evaluation of proliferation, invasion and other malignant biological behaviors.

  8. Statistical properties of $^{243}$Pu, and $^{242}$Pu(n,$\\gamma$) cross section calculation

    CERN Document Server

    Laplace, T A; Guttormsen, M; Larsen, A C; Bleuel, D L; Bernstein, L A; Goldblum, B L; Siem, S; Garotte, F L Bello; Brown, J A; Campo, L Crespo; Eriksen, T K; Giacoppo, F; Görgen, A; Hadyńska-Klȩk, K; Henderson, R A; Klintefjord, M; Lebois, M; Renstrøm, T; Rose, S J; Sahin, E; Tornyi, T G; Tveten, G M; Voinov, A; Wiedeking, M; Wilson, J N; Younes, W

    2015-01-01

    The level density and gamma-ray strength function (gammaSF) of 243Pu have been measured in the quasi-continuum using the Oslo method. Excited states in 243Pu were populated using the 242Pu(d,p) reaction. The level density closely follows the constant-temperature level density formula for excitation energies above the pairing gap. The gammaSF displays a double-humped resonance at low energy as also seen in previous investigations of actinide isotopes. The structure is interpreted as the scissors resonance and has a centroid of omega_{SR}=2.42(5)MeV and a total strength of B_{SR}=10.1(15)mu_N^2, which is in excellent agreement with sum-rule estimates. The measured level density and gammaSF were used to calculate the 242Pu(n,gamma) cross section in a neutron energy range for which there were previously no measured data.

  9. 232Th、233U、238Pu、240Pu、242Pu、241Am、242Cm、243Cm和244Cm的裂变释放热能研究%Thermal Energy Released in Fission of 232 Th,233 U,238 Pu, 240 Pu,242 Pu,241 Am,242 Cm,243 Cm and 244 Cm

    Institute of Scientific and Technical Information of China (English)

    赵艳飞; 马续波; 陈义学

    2013-01-01

    In the nuclear reactor design ,the precise calculation of thermal fission energy is of great significance .In the pressurized water reactor ,high energy neutron-induced fission rarely occurs ,the isotopes including 233 U ,241 Am and 243 Cm are mostly induced by thermal neutrons ,while the other isotopes such as 232Th ,238Pu ,240Pu ,242Pu ,242Cm and 244 Cm are by fast neutron . In order to carry out this work , the nuclear data extracted from the latest evaluated nuclear data file (ENDF/B-Ⅶ ) were adopted ,and the energy-conservation law for the calculation of total fission energy were used , meanw hile ,with the consideration of capture energy and the correction of βand γ ,the thermal fission energy of nine isotopes was obtained .Compared with the data excerpted from IAEA issued WIMS-D database ,the results are reasonable .The thermal fission energy and its uncertainties of the nine isotopes are :(193.939 ± 0.176) MeV for 232 Th , (200.063 ± 0.084) MeV for 233 U ,(208.786 ± 1.133 ) MeV for 238 Pu ,(211.266 ± 0.220 ) MeV for 240 Pu ,(213.862 ± 0.299 ) MeV for 242 Pu ,(215.077 ± 0.210 ) MeV for 241 Am ,(218.821 ± 0.159) MeV for 242Cm ,(218.525 ± 0.388) MeV for 243Cm ,and (220.067 ± 0.131) MeV for 244 Cm ,respectively .%在核反应堆设计中,对每次裂变释放热能进行精确计算具有重要意义。在压水堆内,高能中子诱发核裂变份额很小,233 U、241 Am、243 Cm主要由热中子诱发裂变,232 T h、238 Pu、240 Pu、242 Pu、242 Cm、244 Cm主要由快中子诱发裂变。本文采用最新的核评价数据库 ENDF/B-Ⅶ,利用质量守恒法计算裂变释放总能,同时研究了中微子带走的能量,中子俘获能及β、γ修正项,最终给出了9种核素裂变释放热能。与IAEA颁布的WIMS-D格式数据库中的裂变释放热能数据的对比表明,本文所用方法计算结果合理。9种核素每次裂变释放热能分别为:232 Th ,(193.939±0.176) MeV ;233 U ,(200.063

  10. Process control plan for 242-A Evaporator Campaign 95-1

    Energy Technology Data Exchange (ETDEWEB)

    Le, E.Q.; Guthrie, M.D.

    1995-05-18

    The wastes from tanks 106-AP, 107-AP, and 106-AW have been selected to be candidate feed wastes for Evaporator Campaign 95-1. The wastes in tank 106-AP and 107-AP are primarily from B-Plant strontium processing and PUREX neutralized cladding removal, respectively. The waste in tank 106-AW originated primarily from the partially concentrated product from 242-A Evaporator Campaign 94-2. Approximately 8.67 million liters of waste from these tanks will be transferred to tank 102-AW during the campaign. Tank 102-AW is the dedicated waste feed tank for the evaporator and currently contains 647,000 liters of processable waste. The purpose of the 242-A Evaporator Campaign 95-1 Process Control Plan (hereafter referred to as PCP) is to certify that the wastes in tanks 106-AP, 107-AP, 102-AW, and 106-AW are acceptable for processing through evaporator and provide a general description of process strategies and activities which will take place during Campaign 95-1. The PCP also summarizes and presents a comprehensive characterization of the wastes in these tanks.

  11. Direct Detection of Pu-242 with a Metallic Magnetic Calorimeter Gamma-Ray Detector

    Science.gov (United States)

    Bates, C.; Pies, C.; Kempf, S.; Hengstler, D.; Fleischmann, A.; Gastaldo, L.; Enss, C.; Friedrich, S.

    2016-07-01

    Cryogenic high-resolution γ -ray detectors can improve the accuracy of non-destructive assay (NDA) of nuclear materials in cases where conventional high-purity germanium detectors are limited by line overlap or by the Compton background. We have improved the performance of gamma detectors based on metallic magnetic calorimeters (MMCs) by separating the 0.5 × 2 × 0.25 mm3 Au absorber from the Au:Er sensor with sixteen 30-\\upmu m-diameter Au posts. This ensures that the entire γ -ray energy thermalizes in the absorber before heating the Au:Er sensor, and improves the energy resolution at 35 mK to as low as 90 eV FWHM at 60 keV. This energy resolution enables the direct detection of γ -rays from Pu-242, an isotope that cannot be measured by traditional NDA and whose concentration is therefore inferred through correlations with other Pu isotopes. The Pu-242 concentration of 11.11 ± 0.42 % measured by NDA with MMCs agrees with mass spectrometry results and exceeds the accuracy of correlation measurements.

  12. RV SONNE Fahrtbericht / Cruise Report SO242-2 [SO242/2]: JPI OCEANS Ecological Aspects of Deep-Sea Mining, DISCOL Revisited, Guayaquil - Guayaquil (Equador), 28.08.-01.10.2015

    OpenAIRE

    2015-01-01

    The scientific work during SO242/2 (28. August - 01. October 2015) was part of the JPIO Pilot Action ‘Ecological Aspects of Deep-Sea Mining‘. The main goal was to study the potential long-term ecological impact of anthropogenic disturbances on the deep-sea floor from mining polymetallic Mn-nodules. The expedition SO242 built on studies of the former German TUSCH projects (1989-1996) with four RV SONNE cruises to the DISCOL Experimental Area in the Peru Basin, South Pacific (7°S...

  13. Flurbiprofen benzyl nitrate (NBS-242 inhibits the growth of A-431 human epidermoid carcinoma cells and targets ß-catenin

    Directory of Open Access Journals (Sweden)

    Nath N

    2013-05-01

    Full Text Available Niharika Nath,1,2 Xiaoping Liu,3 Lloydine Jacobs,1 Khosrow Kashfi1,3 1Department of Physiology, Pharmacology, and Neuroscience, Sophie Davis School of Biomedical Education, City University of New York Medical School, New York, NY, USA; 2Department of Life Sciences, New York Institute of Technology, New York, NY, USA; 3Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY, USA Background: The Wnt/ß-catenin/T cell factor (TCF signaling pathway is important in the development of nonmelanoma skin cancers (NMSCs. Nitric-oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs are chemopreventive agents consisting of a traditional NSAID attached to an NO-releasing moiety through a chemical spacer. Previously we showed that an aromatic spacer enhanced the potency of a particular NO-NSAID compared to an aliphatic spacer. Methods: We synthesized an NO-releasing NSAID with an aromatic spacer (flurbiprofen benzyl nitrate, NBS-242, and using the human skin cancer cell line A-431, we evaluated its effects on cell kinetics, Wnt/ß-catenin, cyclin D1, and caspase-3. Results: NBS-242 inhibited the growth of A-431 cancer cells, being ~15-fold more potent than flurbiprofen and up to 5-fold more potent than NO-flurbiprofen with an aliphatic spacer, the half maximal inhibitory concentrations (IC50 for growth inhibition being 60 ± 4 µM, 320 ± 20 µM, and 880 ± 65 µM for NBS-242, NO-flurbiprofen, and flurbiprofen, respectively. This effect was associated with inhibition of proliferation, accumulation of cells in the G0/G1 phase of the cell cycle, and an increase in apoptotic cell population. NBS-242 cleaved ß-catenin both in the cytoplasm and the nucleus of A-431 cells. NBS-242 activated caspase-3 whose activation was reflected in the cleavage of procaspase-3. To test the functional consequence of ß-catenin cleavage, we determined the expression of cyclin D1, a Wnt-response gene. NBS-242 reduced cyclin D1 levels

  14. Measurement of the $^{240,242}$Pu(n,f) cross section at the CERN n_TOF facility

    CERN Document Server

    Tsinganis, A; Guerrero, C; Colonna, N; Calviani, M; Vlastou, R; Andriamonje, S; Vlachoudis, V; Gunsing, F; Massimi, C; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Becvár, F; Belloni, F; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chin, M; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gurusamy, P; Hernández-Prieto, A; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kivel, N; Koehler, P; Kokkoris, M; Krtiˇcka, M; Kroll, J; Lampoudis, C; Langer, C; Leal-Cidoncha, E; Lederer, C; Leeb, H; Leong, L S; Losito, R; Mallick, A; Manousos, A; Marganiec, J; Martínez, T; Mastinu, P F; Mastromarco, M; Meaze, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondalaers, W; Paradela, C; Pavlik, A; Perkowski, J; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Robles, M S; Roman, F; Rubbia, C; Sabaté-Gilarte, M; Sarmento, R; Saxena, A; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T; Zugec, P

    2014-01-01

    Knowledge of neutron cross sections of various plutonium isotopes and other minor actinides is crucial for the design of advanced nuclear systems. The $^{240 , 242}$Pu(n,f) cross sections were measured at the CERN n_TOF facility, taking advantage of the wide energy range (from thermal to GeV) and the high instantaneous f ux of the neutron beam. In this work, preliminary results for $^{242}$Pu are presented along with a theoretical cross section calculation performed with the EMPIRE code.

  15. MR imaging of musculoskeletal tumors and tumor mimickers with intravenous gadolinium: experience with 242 patients

    Energy Technology Data Exchange (ETDEWEB)

    May, D.A. [Department of Radiology, Wilford Hall USAF Medical Center, San Antonio, TX (United States)]|[WHMC/PSRD, Lackland AFB, TX (United States); Good, R.B. [Department of Radiology, Wilford Hall USAF Medical Center, San Antonio, TX (United States); Smith, D.K. [Department of Radiology, Wilford Hall USAF Medical Center, San Antonio, TX (United States); Parsons, T.W. [Department of Orthopaedic Surgery, Wilford Hall USAF Medical Center, San Antonio, TX (United States)

    1997-01-01

    Purpose. This pictorial essay reviews our experience with MR scans with gadolinium in patients with musculoskeletal tumors and tumor mimickers. Design. Review of 242 MR scans obtained in the initial evaluation of a possible primary musculoskeletal neoplasm. All scans included a T1-weighted, fat-suppressed sequence following intravenous administration of gadolinium. Results. MR scans with gadolinium did not contribute to differential diagnosis or patient management in 89% of the patients in this series. However, intravenous gadolinium did assist in guiding the biopsy of bulky lesions and evaluating treated tumor beds for possible recurrence. MR scans with gadolinium were sometimes helpful when the differential diagnosis included synovitis, Morton`s neuroma or intramuscular myxoma, and when it was important to differentiate cystic from solid lesions. Conclusions. Routine use of gadolinium in every initial MR examination of a possible musculoskeletal mass is not warranted. However, there are appropriate selected indications for gadolinium administration as outlined above. (orig.). With 19 figs., 1 tab.

  16. Fission cross section measurement of Am-242m using lead slowing-down spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Kai, Tetsuya; Kobayashi, Katsuhei; Yamamoto, Shuji; Fujita, Yoshiaki [Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.; Kimura, Itsuro; Ohkawachi, Yasushi; Wakabayashi, Toshio

    1998-03-01

    By making use of double fission chamber and lead slowing-down spectrometer coupled to an electron linear accelerator, fission cross section for the {sup 242m}Am(n,f) reaction has been measured relative to that for the {sup 235}U(n,f) reaction in the energy range from 0.1 eV to 10 keV. The measured result was compared with the evaluated nuclear data appeared in ENDF/B-VI and JENDL-3.2, of which evaluated data were broadened by the energy resolution function of the spectrometer. Although the JENDL-3.2 data seem to be a little smaller than the present measurement, good agreement can be seen in the general shape and the absolute values. The ENDF/B-VI data are larger more than 50 % than the present values above 3 eV. (author)

  17. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID)

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 3) presents the standards and requirements for the following sections: Safeguards and Security, Engineering Design, and Maintenance.

  18. 40 CFR 415.242 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Science.gov (United States)

    2010-07-01

    ... SOURCE CATEGORY Ammonium Chloride Production Subcategory § 415.242 Effluent limitations guidelines...): Subpart X—Ammonium Chloride Solvay Process Pollutant or pollutant property BPT limitations Maximum for any... point source subject to this subpart and reacting anhydrous ammonia with hydrogen chloride gas...

  19. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 4) presents the standards and requirements for the following sections: Radiation Protection and Operations.

  20. High level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 6) outlines the standards and requirements for the sections on: Environmental Restoration and Waste Management, Research and Development and Experimental Activities, and Nuclear Safety.

  1. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction.

  2. 17 CFR 242.603 - Distribution, consolidation, and display of information with respect to quotations for and...

    Science.gov (United States)

    2010-04-01

    ..., and display of information with respect to quotations for and transactions in NMS stocks. 242.603...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms... with respect to quotations for and transactions in NMS stocks. (a) Distribution of information. (1)...

  3. Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma

    Directory of Open Access Journals (Sweden)

    Cheng L

    2015-11-01

    Full Text Available Lei Cheng,1,* Zuguang Xia,2,3,* Xinyu Bian,1 Guangchao Li,4 Jing Hu,1 Ya Cao,5 Qing Wang,1 Xiaoping Qian1 1Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, 2Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, 3Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 4School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, Guangdong, 5Department of Biological Science and Technology and State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: Mammalian target of rapamycin (mTOR has been shown to be overactive in human colorectal cancer, but the first-generation mTOR inhibitor, rapamycin, has failed to show clinical efficacy against colorectal cancer. On the other hand, although the second-generation mTOR inhibitor, PP242, has exerted substantial efficacy, it was revealed that independent inhibition by PP242 was transient, which could lead to positive-feedback loop to EGFR. Using wild-type KRAS colorectal cancer cells as models, we investigate the treatment efficacy of a widely used anti-EGFR monoclonal antibody, cetuximab, and PP242, alone or in combination in vitro and in vivo. Results of cell viability assays confirmed the synergistic inhibitory effect of PP242 and cetuximab on the survival of Caco-2 and HT-29 cells. Moreover, the ability of cancer-cell invasion and proliferation was also significantly inhibited by the combination therapy when compared with cetuximab or PP242 alone. Interestingly, the percentage of CD44-positive cancer cells was substantially decreased by the combination therapy in comparison with PP242 alone through fluorescence-activated cell sorting. The growth of cancer stem-like cell spheres in vitro was

  4. Neutron diffraction study of δ-alloy Pu{sup 242}–Ga aging

    Energy Technology Data Exchange (ETDEWEB)

    Somenkov, V.A. [National Research Center “Kurchatov Institute”, Moscow (Russian Federation); Blanter, M.S., E-mail: mike.blanter@gmail.com [Moscow State University of Instrumental Engineering and Information Science, Moscow (Russian Federation); Glazkov, V.P. [National Research Center “Kurchatov Institute”, Moscow (Russian Federation); Laushkin, A.V.; Orlov, V.K. [JSC VNIINM n.a. A.A. Bochvar, Moscow (Russian Federation)

    2014-09-15

    In this paper, we report on a continuing neutron diffraction study of the mean-square atom displacements occurring during the long-term self-irradiation of a Pu–Ga alloy. The measurements were performed at room temperature using the sample based on the isotope Pu{sup 242} with low neutron absorption cross-section to which the short-lived isotope Pu{sup 238} (1.4 wt.%) was added to accelerate self-irradiation. We obtain the maximum self-irradiation equivalent time of 35.5 years, 12 years longer than in our previous papers. In the entire range of self-irradiation time a single fcc phase is preserved. It was found that after the two stages of change in the mean-square displacements we observed earlier (rapid growth up to ∼5–6 equivalent years and a slow decline in the range of ∼6–25 years), comes a stage of stabilization (after ∼25 years). The stabilization can be explained by the emergence of a balance between the formation of point defects and their absorption by helium bubbles and dislocation loops which accumulated over time.

  5. The Mysterious Morphology of MRC0943-242 as Revealed by ALMA and MUSE

    CERN Document Server

    Gullberg, Bitten; Lehnert, Matthew D; Vernet, Joel; Bacon, Roland; Drouart, Guillaume; Emonts, Bjorn; Galametz, Audrey; Ivison, Rob; Nesvadba, Nicole P H; Richard, Johan; Seymour, Nick; Stern, Daniel; Wylezalek, Dominika

    2015-01-01

    We present a pilot study of the z=2.923 radio galaxy MRC0943-242, where we for the first time combine information from ALMA and MUSE data cubes. Even with modest integration times, we disentangle an AGN and a starburst dominated set of components. These data reveal a highly complex morphology, as the AGN, starburst, and molecular gas components show up as widely separated sources in dust continuum, optical continuum and CO line emission observations. CO(1-0) and CO(8-7) line emission suggest that there is a molecular gas reservoir offset from both the dust and the optical continuum that is located ~90kpc from the AGN. The UV line emission has a complex structure in emission and absorption. The line emission is mostly due to i) a large scale ionisation cone energised by the AGN, ii) a Ly-alpha emitting bridge of gas between the radio galaxy and a heavily star-forming set of components. Strangely, the ionisation cone has no Ly-alpha emission. We find this is due to an optically thick layer of neutral gas with u...

  6. Fast, low-ionization emission regions of the planetary nebula M2-42

    CERN Document Server

    Danehkar, A; Steffen, W

    2016-01-01

    Spatially resolved observations of the planetary nebula M2-42 (PN G008.2-04.8) obtained with the Wide Field Spectrograph on the Australian National University 2.3 m telescope have revealed the remarkable features of bipolar collimated jets emerging from its main structure. Velocity-resolved channel maps derived from the [N II] $\\lambda$6584 emission line disentangle different morphological components of the nebula. This information is used to develop a three-dimensional morpho-kinematic model, which consists of an equatorial dense torus and a pair of asymmetric bipolar outflows. The expansion velocity of about 20 km s$^{-1}$ is measured from the spectrum integrated over the main shell. However, the deprojected velocities of the jets are found to be in the range of 80-160 km s$^{-1}$ with respect to the nebular center. It is found that the mean density of the collimated outflows, 595 $\\pm$ 125 cm$^{-3}$, is five times lower than that of the main shell, 3150 cm$^{-3}$, whereas their singly ionized nitrogen and ...

  7. New measurement of the 242Pu(n,γ) cross section at n_TOF

    Science.gov (United States)

    Lerendegui-Marco, J.; Guerrero, C.; Cortés-Giraldo, M. A.; Quesada, J. M.; Mendoza, E.; Cano-Ott, D.; Eberhardt, K.; Junghans, A.

    2016-03-01

    The use of MOX fuel (mixed-oxide fuel made of UO2 and PuO2) in nuclear reactors allows substituting a large fraction of the enriched Uranium by Plutonium reprocessed from spent fuel. With the use of such new fuel composition rich in Pu, a better knowledge of the capture and fission cross sections of the Pu isotopes becomes very important. In particular, a new series of cross section evaluations have been recently carried out jointly by the European (JEFF) and United States (ENDF) nuclear data agencies. For the case of 242Pu, the two only neutron capture time-of-flight measurements available, from 1973 and 1976, are not consistent with each other, which calls for a new time-of flight capture cross section measurement. In order to contribute to a new evaluation, we have perfomed a neutron capture cross section measurement at the n_TOF-EAR1 facility at CERN using four C6D6 detectors, using a high purity target of 95 mg. The preliminary results assessing the quality and limitations (background, statistics and γ-flash effects) of this new experimental data are presented and discussed, taking into account that the aimed accuracy of the measurement ranges between 7% and 12% depending on the neutron energy region.

  8. New measurement of the 242Pu(n,γ cross section at n_TOF

    Directory of Open Access Journals (Sweden)

    Lerendegui-Marco J.

    2016-01-01

    Full Text Available The use of MOX fuel (mixed-oxide fuel made of UO2 and PuO2 in nuclear reactors allows substituting a large fraction of the enriched Uranium by Plutonium reprocessed from spent fuel. With the use of such new fuel composition rich in Pu, a better knowledge of the capture and fission cross sections of the Pu isotopes becomes very important. In particular, a new series of cross section evaluations have been recently carried out jointly by the European (JEFF and United States (ENDF nuclear data agencies. For the case of 242Pu, the two only neutron capture time-of-flight measurements available, from 1973 and 1976, are not consistent with each other, which calls for a new time-of flight capture cross section measurement. In order to contribute to a new evaluation, we have perfomed a neutron capture cross section measurement at the n_TOF-EAR1 facility at CERN using four C6D6 detectors, using a high purity target of 95 mg. The preliminary results assessing the quality and limitations (background, statistics and γ-flash effects of this new experimental data are presented and discussed, taking into account that the aimed accuracy of the measurement ranges between 7% and 12% depending on the neutron energy region.

  9. Light charged particle accompanied ternary fission of {sup 242}Cm using the Coulomb and proximity potential

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P.; Krishnan, Sreejith; Priyanka, B. [Kannur University, School of Pure and Applied Physics, Kerala (India)

    2014-04-15

    The cold ternary fission of {sup 242}Cm with {sup 4}He, {sup 10}Be and {sup 14}C as light charged particle has been studied by taking the interacting barrier as the sum of Coulomb and proximity potential with the fragments in equatorial configuration. The favorable fragment combinations are obtained from the cold valley plot (plot of driving potential vs. mass number of fragments) and by calculating the yield for charge minimized fragments. The maximum yield in the {sup 4}He accompanied ternary fission is obtained for the fragmentation channel {sup 104}Mo + {sup 134}Te + {sup 4}He and for the {sup 10}Be accompanied ternary fission, the maximum yield is found for the fragmentation channel {sup 98}Zr + {sup 134}Te + {sup 10}Be. It is to be noted that, in the case of {sup 14}C accompanied ternary fission, the maximum yield is obtained for the fragmentation channel {sup 94}Sr + {sup 134}Te + {sup 14}C and the next higher yield is found for the fragmentation channel {sup 96}Zr + {sup 132}Sn + {sup 14}C. Thus, the fragment combinations with maximum yields reveal the role of doubly magic and near doubly magic nuclei in cold ternary fission. (orig.)

  10. FAST, LOW-IONIZATION EMISSION REGIONS OF THE PLANETARY NEBULA M2-42

    Energy Technology Data Exchange (ETDEWEB)

    Danehkar, A.; Parker, Q. A. [Department of Physics and Astronomy, Macquarie University, Sydney, NSW 2109 (Australia); Steffen, W., E-mail: ashkbiz.danehkar@cfa.harvard.edu [Instituto de Astronomía, Universidad Nacional Autónoma de México, C.P.22860, Ensenada (Mexico)

    2016-02-15

    Spatially resolved observations of the planetary nebula M2-42 (PN G008.2−04.8) obtained with the Wide Field Spectrograph on the Australian National University 2.3 m telescope have revealed the remarkable features of bipolar collimated jets emerging from its main structure. Velocity-resolved channel maps derived from the [N ii] λ6584 emission line disentangle different morphological components of the nebula. This information is used to develop a three-dimensional morpho-kinematic model, which consists of an equatorial dense torus and a pair of asymmetric bipolar outflows. The expansion velocity of about 20 km s{sup −1} is measured from the spectrum integrated over the main shell. However, the deprojected velocities of the jets are found to be in the range of 80–160 km s{sup −1} with respect to the nebular center. It is found that the mean density of the collimated outflows, 595 ± 125 cm{sup −3}, is five times lower than that of the main shell, 3150 cm{sup −3}, whereas their singly ionized nitrogen and sulfur abundances are about three times higher than those determined from the dense shell. The results indicate that the features of the collimated jets are typical of fast, low-ionization emission regions.

  11. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

    DEFF Research Database (Denmark)

    Shi, Yongyong; Li, Zhiqiang; Xu, Qi;

    2011-01-01

    Schizophrenia is a severe mental disorder affecting ~1% of the world population, with heritability of up to 80%. To identify new common genetic risk factors, we performed a genome-wide association study (GWAS) in the Han Chinese population. The discovery sample set consisted of 3,750 individuals...... with schizophrenia and 6,468 healthy controls (1,578 cases and 1,592 controls from northern Han Chinese, 1,238 cases and 2,856 controls from central Han Chinese, and 934 cases and 2,020 controls from the southern Han Chinese). We further analyzed the strongest association signals in an additional independent cohort...... of 4,383 cases and 4,539 controls from the Han Chinese population. Meta-analysis identified common SNPs that associated with schizophrenia with genome-wide significance on 8p12 (rs16887244, P = 1.27 × 10(-10)) and 1q24.2 (rs10489202, P = 9.50 × 10(-9)). Our findings provide new insights...

  12. Estimated (n,f) cross sections for 236,236m237,238-Np, 237,237m-Pu, and 240,241,242,242m,243,244,244m-Am isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Younes, W; Becker, J; Britt, H

    2004-01-16

    Neutron-induced fission cross sections on targets of {sup 236,236m,237,238}Np, {sup 237,237m}Pu, and {sup 240,241,242,242m,243,244,244m}Am have been estimated for incident neutron energies of up to 6 MeV, using the ''surrogate'' technique and the ({sup 3}He,df) and ({sup 3}He,tf) reactions on stable targets to measure fission probabilities. In isotopes where low-lying isomeric states are known to exist, the (n,f) cross section on the corresponding isomeric targets has been estimated, using the surrogate technique. For targets of {sup 237}Np, {sup 241}Am, {sup 242m}Am, {sup 243}Am, measurements of the (n,f) cross section exist, and comparison with the surrogate-method results suggests that the (n,f) cross sections estimated by the surrogate technique are reliable to within 10% for incident neutron energies E{sub n}{approx}>2 MeV. Tabulated values of the estimated (n,f) cross sections are given in an appendix.

  13. Measurement of the $^{242}$Pu(n,f) reaction cross-section at the CERN n_TOF facility

    CERN Document Server

    AUTHOR|(CDS)2080481; Kokkoris, Michael; Vlachoudis, Vasilis

    The accurate knowledge of relevant nuclear data, such as the neutron-induced fission cross sections of various plutonium isotopes and other minor actinides, is crucial for the design of advanced nuclear systems as well as the development of comprehensive theoretical models of the fission process. The $^{242}$Pu(n,f) cross section was measured at the CERN n_TOF facility taking advantage of the wide energy range and the high instantaneous flux of the neutron beam. In this work, results for the $^{242}$Pu(n,f) measurement are presented along with a detailed description of the experimental setup, Monte-Carlo simulations and the analysis procedure, and a theoretical cross section calculation performed with the EMPIRE code.

  14. Use of inductor agents GSE24.2 for producing pharmaceutical compositions for treating illnesses relating to cellular senescence

    OpenAIRE

    2010-01-01

    This invention relates to the use of an inductor or activator compound GSE24.2 for producing a medicament or a pharmaceutical composition for treating a preferably human illness or pathological situation caused by a senescence process. Said pharmaceutical composition can be useful for a treatment for regenerating tissues, for example of epithelial tissues or haematopoietic cells, and also for the immortalisation of eucaryotic cells in order to use of same in biotechnological investigation or ...

  15. Measurement of the 242Pu(n,f) Cross Section at the CERN n_TOF Facility

    CERN Document Server

    Tsinganis, A; Guerrero, C; Colonna, N; Calviani, M; Vlastou, R; Andriamonje, S; Vlachoudis, V; Gunsing, F; Massimi, C; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Bečvář, F; Belloni, F; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chin, M; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gurusamy, P; Hernández-Prieto, A; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kivel, N; Koehler, P; Kokkoris, M; Krtička, M; Kroll, J; Lampoudis, C; Langer, C; Leal-Cidoncha, E; Lederer, C; Leeb, H; Leong, L S; Losito, R; Mallick, A; Manousos, A; Marganiec, J; Martínez, T; Massimi, C; Mastinu, P F; Mastromarco, M; Meaze, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondalaers, W; Paradela, C; Pavlik, A; Perkowski, J; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Robles, M S; Roman, F; Rubbia, C; Sabaté-Gilarte, M; Sarmento, R; Saxena, A; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T; Žugec, P

    2014-01-01

    The accurate knowledge of relevant nuclear data is crucial for the design of advanced nuclear systems. These data include neutron cross sections of various plutonium isotopes and other minor actinides. The Pu-242(n,f) cross section was measured at the CERN n\\_TOF facility, taking advantage of the wide energy range (from thermal to GeV) and the high instantaneous flux of the neutron beam. Preliminary results for the measurement are presented.

  16. Sikap Mendua Amerika Serikat Terhadap Resolusi Dewan Keamanan PBB No. 242 Tahun 1967 Dalam Penyelesaian Konflik Palestina-Israel

    OpenAIRE

    2008-01-01

    Skripsi ini berjudul “Sikap Mendua Amerika Serikat terhadap Resolusi Dewan Keamanan PBB No. 242/1967 dalam Penyelesaian Konflik Palestina-Israel”. Dalam skripsi ini, Penulis membahas tentang beberapa permasalahan yang terjadi. Adapun masalah-masalah yang diangkat dalam skripsi ini adalah : (1) Peran dari resolusi-resolusi yang telah dibuat dan dikeluarkan sebagai jalan tengah dari penyelesaian konflik; (2) Sikap mendua yang ditunjukkan oleh Negeri Paman Sam dalam penyelesaian Konflik Timur Te...

  17. Identification of a genetic locus for ichthyosis vulgaris on chromosome 10q22.3-q24.2.

    Science.gov (United States)

    Liu, Ping; Yang, Qingyu; Wang, Xu; Feng, Aiping; Yang, Tao; Yang, Rong; Wang, Pengyun; Yuang, Mingxiong; Liu, Mugen; Liu, Jing Yu; Wang, Qing K

    2008-06-01

    Ichthyosis vulgaris (IV) is one of the most commonly inherited disorders and has an estimated prevalence rate of 2.29% in China. To date, only one gene responsible for IV, the filaggrin gene (FLG), was identified, but genetic heterogeneity exists. In this study, two Chinese families with autosomal-dominant IV were genetically characterized. The FLG gene was first excluded as the disease-causing gene in the two families. The larger family was then characterized by genome-wide linkage analysis to identify a new genetic locus for IV. Significant linkage was identified with markers on chromosome 10q22.3-q24.2 with a maximum LOD score of 3.19. No other markers showed a LOD score of >1.5. Fine mapping defined the new genetic locus within a 20.7 cM region between markers D10S569 and D10S1709. The second family also showed positive linkage to the same 10q22.3-q24.2 region. The combined maximum LOD score in the two families was 3.95. Identification of linkage in two independent families provides strong genetic evidence that a previously unreported gene for IV is located on chromosome 10q22.3-q24.2. Future studies of the candidate genes at the 10q IV locus will identify a specific gene, which will provide insights into the pathogenesis of IV.

  18. The Solubility of 242PuO2 in the Presence of Aqueous Fe(II): The Impact of Precipitate Preparation

    Energy Technology Data Exchange (ETDEWEB)

    Felmy, Andrew R.; Moore, Dean A.; Buck, Edgar C.; Conradson, Steven D.; Kukkadapu, Ravi K.; Sweet, Lucas E.; Abrecht, David G.; Ilton, Eugene S.

    2014-01-28

    The solubility of different forms of precipitated 242PuO2(am) were examined in solutions containing aqueous Fe(II) over a range of pH values. The first series of 242PuO2(am) suspensions were prepared from a 242Pu(IV) stock that had been treated with thenoyltrifluoroacetone (TTA) to remove the 241Am originating from the decay of 241Pu. These 242PuO2(am) suspensions showed much higher solubilities at the same pH value and Fe(II) concentration than previous studies using 239PuO2(am). X ray absorption fine structure (XAFS) spectroscopy of the precipitates showed a substantially reduced Pu-Pu backscatter over that previously observed in 242PuO2(am) precipitates, indicating that the 242PuO2(am) precipitates purified using TTA lacked the long range order previously found in 239PuO2(am) precipitates. The Pu(IV) stock solution was subsequently repurified using an ion exchange resin and an additional series of 242PuO2(am) precipitates prepared. These suspensions showed higher redox potentials and total aqueous Pu concentrations than the TTA purified stock solution. The higher redox potential and aqueous Pu concentrations were in general agreement with previous studies on 242PuO2(am) precipitates, presumably due to the removal of possible organic compounds originally present in the TTA purified stock. 242PuO2(am) suspensions prepared with both stock solutions showed almost identical solubilities in Fe(II) containing solutions even though the initial aqueous Pu concentrations before the addition of Fe(II) were orders of magnitude different. By examining the solubility of 242PuO2(am) prepared from both stocks in this way we have essentially approached equilibrium from both the undersaturated and oversaturated

  19. 恩平24-2油田水平井钻井液技术研究%Study of Drilling Fluid for Horizontal Well in Oil Field EP24-2

    Institute of Scientific and Technical Information of China (English)

    胡友林; 岳前升; 刘书杰; 朱磊

    2014-01-01

    为满足恩平24-2油田水平井钻井工程和储层保护需要,通过实验研制出一种无固相快速弱凝胶钻井液体系.室内评价试验表明:该钻井液具有较高的动塑比和较高低剪切速率黏度(LSRV),能有效克服水平井段携岩难、易形成岩屑床的问题.具有优异的抑制性和润滑性,且滤失量较小,具有较强的抗温、抗污染能力、井眼净化能力和储层保护能力.针对恩平24-2油田水平井采用裸眼完井工艺,研究了破胶剂JPC对钻井液及其滤饼的破胶性能,破胶剂JPC能有效解除聚合物对储层造成的污染.研究结果表明,该钻井液具有独特的流变性,维护简单,优异的储层保护性能和较好的可降解性,适用于恩平24-2油田水平井水平段的钻进.

  20. The solubility of {sup 242}PuO{sub 2} in the presence of aqueous Fe(II). The impact of precipitate preparation

    Energy Technology Data Exchange (ETDEWEB)

    Felmy, Andrew R.; Moore, Dean A.; Buck, Edgar; Kukkadapu, Ravi; Sweet, Lucas; Abrecht, David; Ilton, Eugene S. [Pacific Northwest National Laboratory, Richland, WA (United States); Conrados, Steven D. [Los Alamos National Laboratory, Los Alamos, NM (United States)

    2014-07-01

    The solubility of different forms of precipitated {sup 242}PuO{sub 2}(am) were examined in solutions containing aqueous Fe(II) over a range of pH values. The first series of {sup 242}PuO{sub 2}(am) suspensions were prepared from a {sup 242}Pu(IV) stock that had been treated with thenoyltrifluoroacetone (TTA) to remove the {sup 241}Am originating from the decay of {sup 241}Pu. These {sup 242}PuO{sub 2}(am) suspensions showed much higher solubilities at the same pH value and Fe(II) concentration than previous studies using {sup 239}PuO{sub 2}(am). X-ray absorption fine structure (XAFS) spectroscopy of the precipitates showed a substantially reduced Pu-Pu backscatter over that previously observed in {sup 239}PuO{sub 2}(am) precipitates, indicating that the {sup 242}PuO{sub 2}(am) precipitates purified using TTA lacked the long range order previously found in{sup 239}PuO{sub 2}(am) precipitates. The Pu(IV) stock solution was subsequently re-purified using an ion exchange resin and an additional series of {sup 242}PuO{sub 2}(am) precipitates prepared. These suspensions showed higher redox potentials and total aqueous Pu concentrations than the TTA purified stock solution. The higher redox potential and aqueous Pu concentrations were in general agreement with previous studies on {sup 242}PuO{sub 2}(am) precipitates, presumably due to the removal of possible organic compounds originally present in the TTA purified stock. {sup 242}PuO{sub 2}(am) suspensions prepared with both stock solutions showed almost identical solubilities in Fe(II) containing solutions even though the initial aqueous Pu concentrations before the addition of Fe(II) were orders of magnitude different. By examining the solubility of {sup 242}PuO{sub 2}(am) prepared from both stocks in this way we have essentially approached equilibrium from both the undersaturated and oversaturated conditions. The final aqueous Pu concentrations are predictable using a chemical equilibrium model which includes the

  1. 242例未行准分子激光原位角膜磨镶术患者角膜因素分析%Analysis of 242 cases which unable to carry out LASIK

    Institute of Scientific and Technical Information of China (English)

    王林; 张庆生; 王忠海

    2014-01-01

    Objective Analyze the cornea factors which result in unable to carry out the LASIK operation .Method Do retrospective analysis research and summarize 242 patients’ medical records who did not undergo LASIK because of factors in the cornea.Results In total 242 cases, 112 patient’s corneal thickness less than normal that account for the to-tal 46.3%, 87 cases of suspected keratoconus that make up 36.0%of the total, 5 cases (2.1%) of keratoconus , 25 ca-ses (10.3%) are wearing orthokeratology lens , 8 cases (3.3%) are fell ill with keratitis, 5 cases (2.0%) are due to some other corneal problems .Conclusion Corneal factors are the main reasons for unable to carry out the LASIK opera-tions , carry out strict check work on patients ’ cornea to know the relevant indications and contraindications before the oper -ation is very critical to improve the safety of the LASIK operations .%探讨因角膜因素未行准分子激光原位角膜磨镶术( LASIK)的原因。方法回顾分析242例因角膜因素未行LASIK的原因。结果在242例因角膜因素未行LASIK中,角膜厚度不足112例(46.3%),可疑圆锥角膜87例(36.0%),圆锥角膜5例(2.1%),佩戴角膜塑形镜25例(10.3%),角膜炎8例(3.3%),其它角膜因素5例(2.0%)。结论角膜因素是未行LASIK的主要原因,严格的手术前角膜筛查,掌握手术的适应证与禁忌证,可以提高LASIK手术的安全性。

  2. Synthesis of novel 2-(4-(2-morpholinoethoxy)phenyl)-N-phenylacetamide analogues and their antimicrobial study

    Indian Academy of Sciences (India)

    H P Jayadevappa; G Nagendrappa; S Umesh; S Chandrashekar

    2012-09-01

    A new class of potential biologically active 2-(4-(2-morpholinoethoxy)phenyl)-N-phenylacetamides has been synthesized from hydroxyphenylacetic acid. The products were characterized through IR, 1H NMR, mass spectral studies and elemental analysis. The compounds were screened for antimicrobial activity by disc agar diffusion technique. The potency of compounds is tested against variety of fungal and bacterial strains in comparison to clotrimazole and streptomycin, respectively. Some of the synthesized compounds exhibit superior in vitro activity compared to the standard drugs.

  3. Cigarette smoking and colorectal cancer mortality among 602,242 Norwegian males and females

    Directory of Open Access Journals (Sweden)

    Parajuli R

    2014-04-01

    Full Text Available Ranjan Parajuli,1 Eivind Bjerkaas,1 Aage Tverdal,2 Loïc Le Marchand,3 Elisabete Weiderpass1,4–6 Inger T Gram1,7 1Department of Community Medicine, Faculty of Health Sciences UiT, The Arctic University of Norway, Tromsø, Norway; 2Division of Epidemiology, Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway; 3Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA; 4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 5Department of Genetic Epidemiology, Samfundet Folkhälsan, Helsinki, Finland; 6Department of Research, Cancer Registry of Norway, Oslo, Norway; 7Norwegian Centre for Integrated Care and Telemedicine, University Hospital of North Norway, Tromsø, Norway Background: Colorectal cancer (CRC is one of the main cancer types, with high incidence and mortality in Norway. We examined the association between different measures of smoking exposure and CRC mortality overall and by subsite in a large Norwegian cohort. Methods: We followed 602,242 participants from four Norwegian health surveys, aged 19–67 years at enrollment between 1972 and 2003 by linkage to the national registries through December 2007. We used Cox proportional hazard models to estimate hazard ratios (HRs and 95% confidence intervals (CIs by smoking categories for different CRC endpoints. Results: During a mean follow-up of 14 years, 2,333 Norwegian males and females died of CRC (60% men. Male and female ever smokers had a 20% (HR 1.23, CI 1.08–1.40 and HR 1.22, 95% CI 1.06–1.40, respectively increased risk of death from CRC compared with sex-specific never smokers. For proximal colon cancer mortality, female ever smokers had a 50% (HR 1.49, 95% CI 1.20–1.87 increased risk compared with female never smokers. The increased risk of rectal cancer mortality was about 40% higher for male ever smokers (HR 1.43, 95% CI 1.14–1.81 compared with male never smokers. A test for

  4. High-level waste storage tank farms/242-A evaporator standards/requirements identification document (S/RID), Vol. 4

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    Radiation protection of personnel and the public is accomplished by establishing a well defined Radiation Protection Organization to ensure that appropriate controls on radioactive materials and radiation sources are implemented and documented. This Requirements Identification Document (RID) applies to the activities, personnel, structures, systems, components, and programs involved in executing the mission of the Tank Farms. The physical boundaries within which the requirements of this RID apply are the Single Shell Tank Farms, Double Shell Tank Farms, 242-A Evaporator-Crystallizer, 242-S, T Evaporators, Liquid Effluent Retention Facility (LERF), Purgewater Storage Facility (PWSF), and all interconnecting piping, valves, instrumentation, and controls. Also included is all piping, valves, instrumentation, and controls up to and including the most remote valve under Tank Farms control at any other Hanford Facility having an interconnection with Tank Farms. The boundary of the structures, systems, components, and programs to which this RID applies, is defined by those that are dedicated to and/or under the control of the Tank Farms Operations Department and are specifically implemented at the Tank Farms.

  5. Comparison of size modulation and conventional standard automated perimetry with the 24-2 test protocol in glaucoma patients

    Science.gov (United States)

    Hirasawa, Kazunori; Shoji, Nobuyuki; Kasahara, Masayuki; Matsumura, Kazuhiro; Shimizu, Kimiya

    2016-05-01

    This prospective randomized study compared test results of size modulation standard automated perimetry (SM-SAP) performed with the Octopus 600 and conventional SAP (C-SAP) performed with the Humphrey Field Analyzer (HFA) in glaucoma patients. Eighty-eight eyes of 88 glaucoma patients underwent SM-SAP and C-SAP tests with the Octopus 600 24-2 Dynamic and HFA 24-2 SITA-Standard, respectively. Fovea threshold, mean defect, and square loss variance of SM-SAP were significantly correlated with the corresponding C-SAP indices (P < 0.001). The false-positive rate was slightly lower, and false-negative rate slightly higher, with SM-SAP than C-SAP (P = 0.002). Point-wise threshold values obtained with SM-SAP were moderately to strongly correlated with those obtained with C-SAP (P < 0.001). The correlation coefficients of the central zone were significantly lower than those of the middle to peripheral zone (P = 0.031). The size and depth of the visual field (VF) defect were smaller (P = 0.039) and greater (P = 0.043), respectively, on SM-SAP than on C-SAP. Although small differences were observed in VF sensitivity in the central zone, the defect size and depth and the reliability indices between SM-SAP and C-SAP, global indices of the two testing modalities were well correlated.

  6. 242Pu as tracer for simultaneous determination of 237Np and 239,240Pu in environmental samples

    DEFF Research Database (Denmark)

    Chen, Q.J.; Dahlgaard, H.; Nielsen, S.P.;

    2002-01-01

    A procedure has been developed using Pu-242 as tracer for simultaneous determination of Np-237 and Pu-239,Pu-240 in environmental samples. The validity of the method has been demonstrated by ICPMS and alpha-spectroscopy for up to 10 gram soil and sediment, seawater up to 200 litres. The paper...... describes a suitable chemical procedure for Np and Pu including a quantitative pre-concentration of neptunium and plutonium, preparation of Np4+ and Pu4+, NP(NO3)(6)(2-) and Pu(NO3)(6)(2-), The ratio of Np-237/Pu-242 (or Np-237/Pu-239) before and after the procedure has been determined using 10 g soil (free...... from Np and Pu) R-before/R-after = 1.004 +/- 3.3% (S.D n = 20) and 1 litre seawater R-before/R-after = 1.019+/-1.9% (S.D., n = 12). Results from the intercomparison samples LAEA-135, LAEA-381 and from environmental samples are presented....

  7. Research on the controlling of rare earth permanent magnet brushless DC motor based on TMS320C242%基于TMS320C242的稀土永磁无刷直流电机控制系统研究

    Institute of Scientific and Technical Information of China (English)

    董艺

    2012-01-01

    对用TMS320C242控制稀土永磁无刷直流电机(REPMBLDCM)进行了深入的探讨。作为驱动设备,稀土永磁无刷直流电机在很多方面性能优于普通直流电机;作为控制核心,TMS320C242无论是集成度还是控制速度都远超普通的单片机。所以用TMS320C242控制REPMBLDCM可获得极为优秀的控制效果和驱动性能。%A deep discussion has been made on how to control rare earth permanent magnet brushless DC motor with TMS320C242. As a driving device, rare earth permanent magnet brushless DC motor is superior to the common DC motor in many ways. As a core of the control system, TMS320C242 is far more superior to the common single chip microcontroller unit whether on its integration or its controlling speed. Therefore, excellent control effects and driving properties can be obtained by adopting TMS320C242 to control REPMBLDCM.

  8. Relationship between peripheral and mesenteric serum levels of CEA and CA 242 with staging and histopathological variables in colorectal adenocarcinoma Níveis séricos periféricos e mesentéricos de CEA e CA 242, estadiamento e variáveis histopatológicas no adenocarcinoma colorretal

    Directory of Open Access Journals (Sweden)

    Mauro Lamelas Cardoso

    2009-10-01

    Full Text Available PURPOSE: To compare histopathological variables and staging in colorectal adenocarcinoma cases with CEA and CA 242 in peripheral and mesenteric blood. METHODS: In 169 individuals underwent surgery for colorectal cancer, CEA and CA 242 were analyzed and compared to mesenteric and peripheral blood and correlated with macroscopic tumor's morphology and size, degree of cell differentiation, venous, neural and lymphatic involvement and TNM classification. RESULTS: There was a difference between the mesenteric (M and peripheral (P serum levels of CEA (p=0.020. Higher levels of markers were correlated with venous invasion CEA (P p=0.013, CEA (M p=0.05, CA 242 (M p=0.005 and CA 242 (P p=0.038; with advanced staging CEA (P OBJETIVO: Comparar variáveis histopatológicas e graus de estadiamento do adenocarcinoma colorretal com níveis sanguíneos periféricos e mesentéricos de CEA e CA-242. MÉTODOS: Em 169 doentes submetidos ao tratamento cirúrgico por adenocarcinoma colorretal, CEA e CA-242 foram analisados e comparados quanto aos níveis sanguíneos periféricos e mesentéricos e correlacionados com o tamanho e a morfologia macroscópica do tumor, grau de diferenciação celular, invasões venosa, linfática, neural e a classificação TNM. RESULTADOS: Verificou-se diferença significante entre o nível sérico mesentérico e periférico de CEA (p= 0,02. Níveis séricos mais elevados dos marcadores foram observados e correlacionados com invasão venosa, CEA (P p=0,013, CEA(M, p=0,05, CA-242 (M p=0,005 e CA-242 (P p=0,038. Grau de estadiamento TNM avançado foi associado com CEA(P < CEA(M p<0,05, CA-242(P < CA-242(M p<0,05. Nas maiores dimensões tumorais constatou-se CEA(P < CEA(M p=0,001 e CA 242 (P < CA 242 (M (p < 0.001. O CA 242 periférico e mesentérico aumentados associaram-se com a invasão neural, p=0.014 e p=0.003, respectivamente. CONCLUSÕES: O nível sérico mesentérico de CEA é superior ao nível sérico periférico. Os níveis s

  9. Measurement of the fission cross-section of $^{240}$Pu and $^{242}$Pu at CERN's n_TOF Facility

    CERN Multimedia

    Pavlik, A F; Gonzalez romero, E M

    The n_TOF Collaboration proposes to continue the fission program, already started in 2002-2004, taking advantage of the newly constructed Work Sector Type A, with the measurement of the two isotopes : $^{240}$ Pu and $^{242}$ Pu. They are both of major importance for reactor physics applications and are included in the Nuclear Energy Agency (NEA) High Priority List [1], in the NEA WPEC Subgroup 26 Report on the accuracy of nuclear data for advanced reactor designe [2] and in the EU 6$^{th}$ Framework Programme IP-EUROTRANS/NUDATRA reports [3]. Based on those requests, the measurement of the fission cross-section of the two Pu isotopes is one of the objectives of the project ANDES of the FP7 EURATOM program [4].

  10. Clinical analysis of 242 cases of renal transplantations from China donation after citizen death%公民逝世后器官捐献肾移植242例临床分析

    Institute of Scientific and Technical Information of China (English)

    昌盛; 徐晶; 蒋继贫; 陈知水

    2015-01-01

    目的 分析单中心公民逝世后器官捐献(DCD)供肾移植的短期临床效果.方法 对2010年11月至2014年12月31日实施的242例DCD供肾移植的临床资料进行回顾性研究,统计术后1年受者和移植肾存活率,计算术后各类并发症发生率,并观察婴幼儿或儿童以及老年(年龄>60岁)供者供肾移植的临床特点.结果 共计183例DCD捐献者,供者年龄为2d至68岁,其中中国一类(国际标准化脑死亡器官捐献)供者102例,中国二类(国际标准化心死亡器官捐献)供者22例,中国三类(中国过渡时期脑-心双死亡标准器官捐献)供者59例.最终捐献247个肾脏用于移植,实施肾移植242例,其中单肾移植237例,双肾移植5例.受者年龄为(43.3±21.8)岁(12~64岁).术后1年受者总体存活率为93.8%(227/242),低于既往传统尸体肾移植95.4%的存活率,但差异无统计学意义(P>0.05).术后1年移植肾总体存活率为90.5%(219/242),低于既往传统尸体肾移植94.3%的存活率(P<0.05).术后DGF的发生率为33.1%(80/242),高于既往传统尸体肾移植23.6%的发生率(P<0.05).而术后1年急性排斥反应发生率、间质性肺炎发生率以及尿瘘、输尿管梗阻、心脑血管意外等并发症发生率与既往传统尸体肾移植相比较,差异无统计学意义(P>0.05).婴幼儿及儿童供肾移植总体结果良好,移植肾体积在术后3个月之内生长至接近成人肾脏大小.老年供肾弃用率高于总弃用率(P<0.05),但总体移植效果良好.结论 对于DCD供肾移植,严格筛选供者、加强供者濒死期器官维护、综合评估器官质量是提高受者长期存活、降低术后并发症发生率的关键.未成年供者供肾移植是解决供肾短缺的一条可行途径,无论是双肾移植还是单肾移植,均可获得优良的远期效果.而年龄>60岁供者供肾尽管弃用率较高,但只要肾脏质量评估得当,并不影响短期疗效.%Objective To

  11. Method for Determination of Neptunium in Large-Sized Urine Samples Using Manganese Dioxide Coprecipitation and 242Pu as Yield Tracer

    DEFF Research Database (Denmark)

    Qiao, Jixin; Hou, Xiaolin; Roos, Per

    2013-01-01

    A novel method for bioassay of large volumes of human urine samples using manganese dioxide coprecipitation for preconcentration was developed for rapid determination of 237Np. 242Pu was utilized as a nonisotopic tracer to monitor the chemical yield of 237Np. A sequential injection extraction chr...

  12. C242T Polymorphism in CYBA Gene (p22phox and Risk of Coronary Artery Disease in a Population of Caucasian Italians

    Directory of Open Access Journals (Sweden)

    Sabina Nasti

    2006-01-01

    Full Text Available Background: specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system.

  13. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 7. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Burt, D.L.

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 7) presents the standards and requirements for the following sections: Occupational Safety and Health, and Environmental Protection.

  14. TAK-242 Protects Against Apoptosis in Coronary Microembolization-Induced Myocardial Injury in Rats by Suppressing TLR4/NF-κB Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Xian-tao Wang

    2017-03-01

    Full Text Available Background/Aims: Myocardial apoptosis is heavily implicated in the myocardial injury caused by coronary microembolization (CME, and toll-like receptor 4 (TLR4 is considered to be involved in this apoptotic cascade. Therefore, the present study was designed to investigate the role of TLR4/NF-κB signaling pathway regulated by TAK-242, a selective TLR4 signal transduction inhibitor, in the myocardial apoptosis after CME in rats. Methods: Forty-five rats were randomized (random number into three groups: sham, CME and CME + TAK-242 (n = 15 per group.CME was induced by injecting polyethylene microspheres (42µm into the left ventricular except the sham group. CME + TAK-242 group was treated with TAK-242 (2mg/kg via the tail vein 30 minutes before CME modeling. Cardiac function was evaluated 6 hours after operation. Tissue biopsy was stained with HBFP to measure the size of micro-infarction area. TUNEL staining was used to detect myocardial apoptosis. Western blot and qPCR were used to evaluate the expression of TLR4, MyD88, NF-κB p65, p-IκBα and Cleaved caspase-3. Results: Cardiac function in the CME group and CME + TAK-242 group were significantly decreased compared with the sham group (P < 0.05 and the micro-infarction area, the apoptotic index, the expression of TLR4, NF-κB p65, p-IκBα and Cleaved caspase-3 were increased significantly (P < 0.05. Cardiac function in the CME + TAK-242 group was significantly improved compared with the CME group (P < 0.05 and the micro-infarction area, the apoptotic index, the expression of TLR4, MyD88, NF-κB p65, p-IκBα and Cleaved caspase-3 were decreased significantly (P < 0.05. Conclusions: TAK-242 can effectively improve CME-induced cardiac dysfunction by regulating TLR4/NF-κB signaling pathway and then reducing the myocardial apoptosis.

  15. Formation and evolution of a 0.242 Msun helium white dwarf in presence of element diffusion

    CERN Document Server

    Althaus, L G; Benvenuto, O G; Althaus, Leandro; Serenelli, Aldo; Benvenuto, Omar

    2000-01-01

    A 0.242 Msun object that finally becomes a helium white dwarf is evolved from Roche lobe detachment down to very low luminosities. In doing so, we employ our stellar code to which we have added a set of routines that compute the effects due to gravitational settling, and chemical and thermal diffusion. Initial model is constructed by abstracting mass to a 1 Msun red giant branch model up to the moment at which the model begins to evolve bluewards. We find that element diffusion introduces noticeable changes in the internal structure of the star. In particular, models undergo three thermonuclear flashes instead of one flash as we found with the standard treatment. This fact has a large impact on the total mass fraction of hydrogen left in the star at entering the final cooling track. As a result, at late stages of evolution models with diffusion are characterized by a much smaller nuclear energy release, and they evolve significantly faster compared to those found with the standard treatment. We find that mode...

  16. Deep VLT spectroscopy of high redshift radio galaxy MRC 2104-242 Evidence for a metallicity gradient

    CERN Document Server

    Overzier, R; Kurk, J D; De Breuck, C

    2001-01-01

    In this contribution we will present deep VLT spectroscopy observations of the giant emission line halo around the z=2.49 radio galaxy MRC 2104-242. The morphology of the halo is dominated by two spatially resolved regions. Lya is extended by >12" along the radio axis, C IV and He II are extended by ~8". The overall spectrum is typical for that of high redshift radio galaxies. Interestingly, N V is present in the spectrum of the region associated with the center of the galaxy hosting the radio source, the northern region, while absent in the southern region. Using a simple photoionization model, the difference in N V can be explained due to a metallicity gradient within the halo. This is consistent with a scenario in which the halo is formed by a massive cooling flow or originates from the debris of the merging of two or more galaxies. However, also other mechanisms such as jet-cloud interactions or starburst-winds could be important.

  17. Deep vlt spectroscopy of high redshift radio galaxy MRC 2104{242: evidence for a metallicity gradient

    Directory of Open Access Journals (Sweden)

    R. Overzier

    2002-01-01

    Full Text Available En esta contribuci on vamos a presentar observaciones espectrosc opicas profundas del VLT (siglas en ingl es: Very Large Telescope del halo gigante de l neas de emisi on alrededor de la radiogalaxia MRC 2104{242 a z = 2:49. La morfolog a del halo viene determinado por dos regiones espaciales resueltas. Ly se extiende por > 1200 a lo largo del radioeje, C IV 1549 y He II 1640 se extienden por 800. El espectro total es t pico para radiogalaxias de alto corrimiento al rojo. Es interesante notar que N V 1240 est a presente en el espectro de la regi on asociada con el centro de la galaxia que contiene la radiofuente, la regi on del norte, mientras que est a ausente en la regi on del sur. Usando un modelo de fotoionizaci on simple, la diferencia en la emisi on N V 1240 se puede explicar por un gradiente de metalicidad en el halo. Esto es consistente con un escenario en el cual el halo se form o por un "cooling ow" masivo o tiene su origen en los residuos de la fusi on de dos o m as galaxias. Sin embargo, tambi en podr an ser importantes otros mecanismos como son las interacciones entre jets y nubes y los vientos debido a un \\starburst".

  18. Evaluation of n + /sup 242/Pu reactions from 10 keV to 20 MeV. [Total cross sections, neutron emission energy dependence

    Energy Technology Data Exchange (ETDEWEB)

    Madland, D.G.; Young, P.G.

    1978-10-01

    An evaluation of the n + /sup 242/Pu cross sections is presented for the neutron energy range of 10 keV to 20 MeV. The total fission and radiative capture cross sections are based upon experimental measurements on /sup 242/Pu. The remaining cross sections, together with the elastic and inelastic angular distributions to low-lying states, were calculated using various reaction models. An expression is presented for the energy dependence of the average number of neutrons produced per fission. The results were placed in ENDF/B-V format and combined with a recent evaluation of data below 10 keV by the Hanford Engineering Development Laboratory, so that a complete data set covering the energy range of 10/sup -5/ eV to 20 MeV is available. 41 references. (JFP)

  19. Empiema paraneumónico: caracterización y factores asociados a morbi-mortalidad en 242 casos tratados quirúrgicamente Parapneuminic empyema: characterization and factors associated with morbility and mortality in 242 surgical cases

    Directory of Open Access Journals (Sweden)

    Roberto González L

    2012-03-01

    Full Text Available Objetivos: Describir las características y evaluar los factores asociados a morbi-mortalidad en el empiema paraneumónico (EPN tratado quirúrgicamente. Método: Revisión retrospectiva entre Enero 2000 y Agosto 2006. Se describen características y factores asociados a morbi-mortalidad, se realizó análisis univariado y multivariado utilizando programa SPSS 15.0. Resultados: 242 pacientes tenían EPN (70,6% de los empiemas tratados, 165 (68,2% fueron hombres, edad promedio 52,1 años, 229 (94,6% fueron neumonías adquiridas en la comunidad (NAC y 13 (5,4% intrahospitalarias. Se aisló gérmenes en líquido pleural en 57 (23,6%. Se realizaron 183 (75,6% decorticaciones, 49 (20,2% pleurotomías, 7 (2,9%, cirugías video-asistidas y 3 (1,2% decorticaciones con resección pulmonar. Presentaron complicaciones 65 (26,9%. Fallecieron 16 pacientes (6,6%. Se identificaron variables asociadas a morbi-mortalidad. Conclusiones: El EPN es la causa más frecuente de empiema, la mayoría está asociado a NAC y en pocos se identifican gérmenes. La decorticación es el procedimiento más frecuente. Se identificaron las variables asociadas a morbi-mortalidad en esta serie clínica.Objectives: To describe and evaluate factors associated with morbidity and mortality in surgically treated parapneumonic empyemas (PNE. Method: Retrospective review between January 2000 and August 2006. We described clinical features and we performed univariate and multivariate analysis to find the factors associated with morbidity and mortality. SPSS 15.0 program was used in the statistical analysis. Results: 242 of343 surgically treated empyemas (70.6% were paraneumonic. Of these 165 (68.2% were men, average age 52.1 years, 229 (94.6% were community-acquired pneumonia (CAP and 13 (5.4% nosocomial. Germs were isolated in pleural fluid in 57 (23.6%. Surgical procedures were: 183 (75.6% decortications, 49 (20.2% pleurotomies, 7 (2.9% video-assisted surgery and 3 (1.2% decortications

  20. 242例不同来源高热惊厥患儿电解质水平比较分析%Electrolyte Levels Comparative Analysis of 242 Cases of Febrile Convulsion Children

    Institute of Scientific and Technical Information of China (English)

    张秋生; 徐昀; 陈玉勤

    2012-01-01

    Objective To observe the correlatlonshlp of seruifi electrolyte levels and convulsion from children of dif ferent sources Methods Selected 242 cases hyperpyrexia children aged 13 years,the an seruifi electrolyte levels are compared in simple Febrile Convulsions children group and Febrile non convulsion children group;The mean serum ion ized calcium levels are compared in urban source children group and migrant workers Source group;The convulsions in cidence were compared of urban source children group and migrant workers Source group Results The mean setuifi I onized calcium levels of simple Febrile Convulsions children group (n=130)lower than Febrile non convulsion children group(112 cases)(P<0.05);The mean setuifi ionized calcium levels in migrant workers Source group(143 cases)lower than urban source children group(P<0.05);The incidence of Febrile Convulsions was no significant difference (P>0.05)between urban source children group and migrant workers Source group.Conclusion Hypocalcaemia is a risk factor for the occurrence of simple Febrile Convulsions It should be actively promoted the development of commu nity medical and scientific upbringing and supervision to ensure the reduction of convulsions incidence both of urban source and migrant workers Source children.%目的 观察不同来源的高热患儿血清钙、钠、钾、氯离子的水平与发生惊厥的关系.方法 选择242例1-3岁高热患儿,采集动脉血,应用干化学式血气电解质分析系统进行血气分析.按照单纯性高热惊厥患儿以及高热无惊厥患儿进行分组,比较平均血清离子水平;按照患儿来源于城市或外来务工人员进行分组,比较患儿平均血清离子钙水平,并比较惊厥发生率.结果 高热惊厥患儿血清钙离子水平显著低于高热无惊厥患儿血清离子钙水平(P0.05).结论 低钙是发生高热惊厥的危险因素,对于来源于城市及外来务工人员的儿童,均应积极倡导合理补钙并发

  1. C242T Polymorphism in CYBA Gene (p22phox) and Risk of Coronary Artery Disease in a Population of Caucasian Italians

    Science.gov (United States)

    Nasti, Sabina; Spallarossa, Paolo; Altieri, Paola; Garibaldi, Silvano; Fabbi, Patrizia; Polito, Luisa; Bacino, Luca; Brunelli, Michele; Brunelli, Claudio; Barsotti, Antonio; Ghigliotti, Giorgio

    2006-01-01

    Background: specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system. Design: we investigated whether the C242T nucleotide transition is associated with the presence of coronary artery disease (CAD) in a population of 494 Caucasian Italians undergoing coronary angiography to diagnose the cause of chest pain. Results: the frequency of the T mutant allele that we found in 276 patients with angiographically documented CAD was significantly higher compared to what we observed in 218 subjects with normal coronary arteries (Controls) (respectively: 0.400 and 0.332, p < 0.01). The prevalence of the T allele was even stronger when we compared: 1) early onset (age ≤55) vs late onset (age ≥65) single-vessel CAD patients (respectively: 0.75 and 0.48, p < 0.05), and 2) the subgroup of CAD patients with at least one ≥98% stenosis in a coronary vessel vs those with no ≥98% stenosis in a coronary vessel (respectively: 0.425 and 0.365, p < 0.05). Conclusions: these results support the increased risk of developing early CAD and of having rapid progression of coronary stenosis in subjects carrying the C242T nucleotide transition among the Italian population. PMID:16788250

  2. De Novo 17q24.2-q24.3 microdeletion presenting with generalized hypertrichosis terminalis, gingival fibromatous hyperplasia, and distinctive facial features.

    Science.gov (United States)

    Afifi, Hanan H; Fukai, Ryoko; Miyake, Noriko; Gamal El Din, Amina A; Eid, Maha M; Eid, Ola M; Thomas, Manal M; El-Badry, Tarek H; Tosson, Angie M S; Abdel-Salam, Ghada M H; Matsumoto, Naomichi

    2015-10-01

    Generalized hypertrichosis is a feature of several genetic disorders, and the nosology of these entities is still provisional. Recent studies have implicated chromosome 17q24.2-q24.3 microdeletion and the reciprocal microduplication in a very rare form of congenital generalized hypertrichosis terminalis (CGHT) with or without gingival hyperplasia. Here, we report on a 5-year-old Egyptian girl born to consanguineous parents. The girl presented with CGHT and gingival hyperplasia for whom we performed detailed clinical, pathological, and molecular studies. The girl had coarse facies characterized by bilateral epicanthic folds, thick and abundant eyelashes, a broad nose, full cheeks, and lips that constituted the distinctive facial features for this syndrome. Biopsy of the gingiva showed epithelial marked acanthosis and hyperkeratosis with hyperplastic thick collagen bundles and dense fibrosis in the underlying tissues. Array analysis indicated a 17q24.2-q24.3 chromosomal microdeletion. We validated this microdeletion by real-time quantitative PCR and confirmed a perfect co-segregation of the disease phenotype within the family. In summary, this study indicates that 17q24.2-q24.3 microdeletion caused CGHT with gingival hyperplasia and distinctive facies, which should be differentiated from the autosomal recessive type that lacks the distinctive facies.

  3. Application value discussion of CEA, CA19-9, CA242, CA72-4 in early diagnosis of rectal cancer%CEA、CA19-9、CA242、CA72-4在直肠癌早期诊断的应用价值探讨

    Institute of Scientific and Technical Information of China (English)

    周永玲

    2015-01-01

    目的:探讨联合检测癌胚抗原(CEA)、糖类抗原19-9(Carbohydrate antigen 19-9,CA19-9)、糖类抗原242(carbohydrate antigen 242,CA242)、糖类抗原72-4(Carbohydrate antigen 72-4,CA72-4)对直肠癌早期诊断价值。方法采用化学发光法联合检测直肠癌组、直肠良性病变组和健康对照组血清中 CEA、CA19-9、CA242、CA72-4浓度,并进行统计学分析。结果直肠癌组患者血清中 CEA、CA19-9、CA242、CA72-4的含量均明显高于直肠良性病变组及健康对照组,差异有统计学意义(P<0.05),直肠良性病变组和健康对照组比较差异无统计学意义,直肠癌组患者血清四项标志物联合检测的阳性率:72.587%(45/62)高于 CEA 单项检测的阳性率61.29%(38/62)。结论联合检测血清中 CEA、CA19-9、CA242、CA72-4含量可有显著的互补性效提高直肠癌的诊断诊断率,是早期筛查直肠癌一中简单,有效的方法。%Objective To investigate early diagnosis value of CEA, CA19-9, CA242, CA72-4 for rectal cancer. Methods applying chemiluminescence combined with testing serum concentrations of CEA,CA19-9,CA242,CA72-4 of rectal cancer, rectal benign lesion, health control group, and carry on statistical analyis. Result CEA, CA19-9, CA242 and CA72-4 contents in serum of rectal cancer groups were significantly higher than rectal benign lesion and healthy control group, and difference shows statistical significance(P<0.05). Comparison between rectal benign lesion and healthy control group shows no statistical significance. And positive rate of combination test for four markers in serum of rectal cancer group was 72.587% (45/62), which was higher than 61.29% (38/62) of CEA test only. Conclusion combination test for CEA, CA19-9, CA242 and CA72-4 contents can significantly improve diagnostic rate of rectal cancer, which is a simple and effective method for early screening of rectal cancer.

  4. The A930G polymorphism ofP22phox (CYBA gene but not C242T variation is associated with hypertension: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Yu-Wang Qin

    Full Text Available BACKGROUND: Recently, it has been reported that the A930G and C242T polymorphisms within p22phox (CYBA gene are involved in the pathogenesis of hypertension. However, the results remain controversial. Furthermore, no previous meta-analysis has been conducted to evaluate the relationship between the A930G and C242T polymorphisms and hypertension. Therefore, we performed this meta-analysis to clarify these controversies. OBJECTIVE AND METHODS: All of the included articles were retrieved from the PubMed and Embase databases, as well as the CNKI, CBM, Chongqing VIP and Wan Fang databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA guidelines. Odds ratios (OR with corresponding 95% confidence intervals (CI were used to assess the strength of the association. Accounting for heterogeneity, a fixed or random effects model was respectively adopted. Heterogeneity was checked using the Q test and the I(2 statistic. A cumulative meta-analysis was conducted to estimate the tendency of pooled OR. Funnel plots and Egger's tests were performed to test for possible publication bias. RESULTS: Five articles on A930G with 2003 cases/2434 controls and eight articles on C242T with 2644 cases/1967 controls were identified. A significant association of A930G polymorphisms with the risk of hypertension was found in the dominant model (OR=0.59, 95% CI: 0.38-0.92, p=0.021 and allelic model (OR=0.66, 95% CI: 0.46-0.95, p=0.024. In the stratified analysis, a significant association could be found among the hospital-based and population-based studies. However, no evidence of a significant association of the C242T polymorphism with hypertension was found in the overall analysis and subgroup analysis. CONCLUSIONS: This meta-analysis indicates that the A930G polymorphism, but not the C242T variation, might be a protective factor for hypertension.

  5. The C242T polymorphism of the p22-phox gene (CYBA is associated with higher left ventricular mass in Brazilian hypertensive patients

    Directory of Open Access Journals (Sweden)

    Krieger José E

    2011-08-01

    Full Text Available Abstract Background Reactive oxygen species have been implicated in the physiopathogenesis of hypertensive end-organ damage. This study investigated the impact of the C242T polymorphism of the p22-phox gene (CYBA on left ventricular structure in Brazilian hypertensive subjects. Methods We cross-sectionally evaluated 561 patients from 2 independent centers [Campinas (n = 441 and Vitória (n = 120] by clinical history, physical examination, anthropometry, analysis of metabolic and echocardiography parameters as well as p22-phox C242T polymorphism genotyping. In addition, NADPH-oxidase activity was quantified in peripheral mononuclear cells from a subgroup of Campinas sample. Results Genotype frequencies in both samples were consistent with the Hardy- Weinberg equilibrium. Subjects with the T allele presented higher left ventricular mass/height2.7 than those carrying the CC genotype in Campinas (76.8 ± 1.6 vs 70.9 ± 1.4 g/m2.7; p = 0.009, and in Vitória (45.6 ± 1.9 vs 39.9 ± 1.4 g/m2.7; p = 0.023 samples. These results were confirmed by stepwise regression analyses adjusted for age, gender, blood pressure, metabolic variables and use of anti-hypertensive medications. In addition, increased NADPH-oxidase activity was detected in peripheral mononuclear cells from T allele carriers compared with CC genotype carriers (p = 0.03. Conclusions The T allele of the p22-phox C242T polymorphism is associated with higher left ventricular mass/height2.7 and increased NADPH-oxidase activity in Brazilian hypertensive patients. These data suggest that genetic variation within NADPH-oxidase components may modulate left ventricular remodeling in subjects with systemic hypertension.

  6. Octabutylbis{(E-2-[4-(2-hydroxybenzylideneaminophenyl]acetato}di-μ2-methoxo-di-μ3-oxido-tetratin(IV

    Directory of Open Access Journals (Sweden)

    Wenkuan Li

    2009-11-01

    Full Text Available The title compound, [Sn4(C4H98(C15H12NO32(CH3O2O2], is a centrosymmetric dimer and displays a ladder type structural motif. There are four SnIV centres which can be divided into two sorts, viz. two endocyclic and two exocyclic. The endo- and exocyclic SnIV centres are linked by bidentate deprotonated methanol and μ3-O atoms. Each exocyclic SnIV centre is also coordinated by a monodentate 2-[4-(2-hydroxybenzylideneaminophenyl]acetate ligand. Parts of the butyl groups were found to be disordered over two sets of sites.

  7. Alpha-decay branching ratios to high-lying excited-states of the 242Cm→238pu→ 234U →230Th→226Rn decay chain

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-Juan; XU Chang; REN Zhong-Zhou

    2009-01-01

    We present a systematic calculation on the 0c-decay branching ratios to excited-states of an even-even α-decay chain 242Cm→238pu→234U →230Th→226Rn by the improved barrier penetration approach. The changes of the parities between the parent nuclei and the daughter nuclei are properly taken into account. The theoretical values are compared with the available experimental data and the deviation between them is within a factor of 5 in most cases.

  8. Thermal neutron capture cross-section measurements of {sup 243}Am and {sup 242}Pu using the new mini-INCA {alpha}- and {gamma}-spectroscopy station

    Energy Technology Data Exchange (ETDEWEB)

    Marie, F. [DSM/DAPNIA, CEA-Saclay, 91191 Gif sur Yvette (France); Letourneau, A. [DSM/DAPNIA, CEA-Saclay, 91191 Gif sur Yvette (France)]. E-mail: aletourneau@cea.fr; Fioni, G. [DSM/DAPNIA, CEA-Saclay, 91191 Gif sur Yvette (France); Deruelle, O. [DSM/DAPNIA, CEA-Saclay, 91191 Gif sur Yvette (France); Veyssiere, Ch. [DSM/DAPNIA, CEA-Saclay, 91191 Gif sur Yvette (France); Faust, H. [Institut Laue-Langevin, 38000 Grenoble (France); Mutti, P. [Institut Laue-Langevin, 38000 Grenoble (France); AlMahamid, I. [Lawrence Berkeley National Lab., ESH Division, Berkeley, CA 94720 (United States); Muhammad, B. [Lawrence Berkeley National Lab., ESH Division, Berkeley, CA 94720 (United States)

    2006-01-15

    In the framework of the Mini-INCA project, dedicated to the study of Minor Actinide transmutation process in high neutron fluxes, an {alpha}- and {gamma}-spectroscopy station has been developed and installed at the High Flux Reactor of the Laue-Langevin Institut. This set-up allows short irradiations as well as long irradiations in a high quasi-thermal neutron flux and post-irradiation spectroscopy analysis. It is well suited to measure precisely, in reference to {sup 59}Co cross-section, neutron capture cross-sections, for all the actinides, in the thermal energy region. The first measurements using this set-up were done on {sup 243}Am and {sup 242}Pu isotopes. Cross-section values, at E{sub n}=0.025eV, were found to be (81.8+/-3.6)b for {sup 243}Am and (22.5+/-1.1)b for {sup 242}Pu. These values differ from evaluated data libraries by a factor of 9% and 17%, respectively, but are compatible with the most recent measurements, validating by the way the experimental apparatus.

  9. Impact on Autophagy and Ultraviolet B Induced Responses of Treatment with the MTOR Inhibitors Rapamycin, Everolimus, Torin 1, and pp242 in Human Keratinocytes

    Science.gov (United States)

    Xu, Song; Li, Li; Li, Min; Zhang, Mengli

    2017-01-01

    The mechanistic target of Rapamycin (MTOR) protein is a crucial signaling regulator in mammalian cells that is extensively involved in cellular biology. The function of MTOR signaling in keratinocytes remains unclear. In this study, we detected the MTOR signaling and autophagy response in the human keratinocyte cell line HaCaT and human epidermal keratinocytes treated with MTOR inhibitors. Moreover, we detected the impact of MTOR inhibitors on keratinocytes exposed to the common carcinogenic stressors ultraviolet B (UVB) and UVA radiation. As a result, keratinocytes were sensitive to the MTOR inhibitors Rapamycin, everolimus, Torin 1, and pp242, but the regulation of MTOR downstream signaling was distinct. Next, autophagy induction only was observed in HaCaT cells treated with Rapamycin. Furthermore, we found that MTOR signaling was insensitive to UVB but sensitive to UVA radiation. UVB treatment also had no impact on the inhibition of MTOR signaling by MTOR inhibitors. Finally, MTOR inhibition by Rapamycin, everolimus, or pp242 did not affect the series of biological events in keratinocytes exposed to UVB, including the downregulation of BiP and PERK, activation of Histone H2A and JNK, and cleavage of caspase-3 and PARP. Our study demonstrated that MTOR inhibition in keratinocytes cannot always induce autophagy, and the MTOR pathway does not play a central role in the UVB triggered cellular response.

  10. C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension.

    Science.gov (United States)

    Rafiq, Adnan; Aslam, Khursheed; Malik, Rouf; Afroze, Dil

    2014-05-01

    Vascular oxidative stress is an important factor in hypertension-associated vascular damage and is mediated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation. The C242T polymorphism at the p22PHOX gene affects binding of p22PHOX to heme, leading to variants of NADPH oxidase that produce different levels of reactive oxygen species (ROS). Specific variations in ROS are associated with an altered risk of developing cardiovascular disease. In the present study, 140 permanent Kashmiri-resident individuals were recruited (75 with essential systemic hypertension and 65 normotensive controls). Endothelial function was assessed non-invasively using high-resolution ultrasonography of the brachial artery. Endothelium-dependent vasoreactivity was expressed in terms of flow-mediated dilation. The TT genotype was identified in 2% of hypertensive and 7% of normotensive individuals. Frequency of the T-allele was not observed as significantly different between hypertensive and normotensive individuals (P=0.24; OR=0.4; 95% CI, 0.07-2.2). Blood pressure or the prevalence of hypertension did not vary between C242T p22PHOX genotypes or in the presence or absence of the T-allele.

  11. Diagnostic value of joint detection of serum CA1 9-9,CA125 and CA242 for cholangiocarci-noma%血清 CA 19-9、CA 125、CA242联合检测对胆管癌诊断价值的评价

    Institute of Scientific and Technical Information of China (English)

    崔大鹏; 韩磊; 刘振显; 杨贺; 张迎春

    2016-01-01

    Objective:To study the diagnostic value of joint detection of serum CA1 9-9,CA125 and CA242 for cholan-giocarcinoma.Methods:A total of 35 patients with cholangiocarcinoma who received surgical resection in our hospital were se-lected as malignant group;30 patients with cholelithiasis who received surgical resection in our hospital during the same period were selected as benign group.Serum samples were collected before surgery to determine CA1 9-9,CA125 and CA242 content;and cholangiocarcinoma tissue and normal bile duct tissue were collected after surgery to determine the content of proliferation and invasion molecules.Results:Serum CA1 9-9,CA125 and CA242 levels of malignant group were significantly higher than those of control group (P <0.05);PROX-1,Ki-67,Bcl-2,Bad,Gab1,LOXL2,TRPM7 and CXCL12 levels in cholangiocar-cinoma tissue were significantly higher than those in benign bile duct tissue (P <0.05);and E-cadherin level was significantly lower than that in benign bile duct tissue (P <0.05);serum CA1 9-9,CA125 and CA242 levels were positively correlated with PROX-1,Ki-67,Bcl-2,Bad,Gab1,LOXL2,TRPM7 and CXCL12 levels,and negatively correlated with E-cadherin level. Conclusions:Joint detection of serum CA1 9-9,CA125 and CA242 can not only provide reference for the diagnosis of cholangio-carcinoma,but also can provide basis for the evaluation of proliferation,invasion and other malignant biological behaviors.%目的::研究血清 CA19-9、CA125、CA242联合检测对胆管癌的诊断价值.方法:选择在我院接受手术切除的35例胆管癌患者作为恶性组,同期在我院接受手术切除的30例胆石症患者作为良性组,术前采集血清标本并测定 CA19-9、CA125、CA242含量,术后采集胆管癌组织和正常胆管组织并测定增殖、侵袭分子的含量.结果:恶性组血清中 CA19-9、CA125、CA242的含量显著高于对照组(P <0.05);胆管癌组织中 PROX-1、Ki-67、Bcl-2、Bad、Gab1、LOXL2、TRPM7、CXCL12

  12. Neutron-induced fission cross sections of 242Pu from 0.3 MeV to 3 MeV

    Science.gov (United States)

    Salvador-Castiñeira, P.; Bryś, T.; Eykens, R.; Hambsch, F.-J.; Göök, A.; Moens, A.; Oberstedt, S.; Sibbens, G.; Vanleeuw, D.; Vidali, M.; Pretel, C.

    2015-10-01

    The majority of the next generation of nuclear power plants (GEN-IV) will work in the fast-neutron-energy region, as opposed to present day thermal reactors. This leads to new and more accurate nuclear-data needs for some minor actinides and structural materials. Following those upcoming demands, the Organisation for Economic Cooperation and Development Nuclear Energy Agency performed a sensitivity study. Based on the latter, an improvement in accuracy from the present 20% to 5% is required for the 242Pu(n ,f ) cross section. Within the same project both the 240Pu(n ,f ) cross section and the 242Pu(n ,f ) cross section were measured at the Van de Graaff accelerator of the Joint Research Centre at the Institute for Reference Materials and Measurements, where quasimonoenergetic neutrons were produced in an energy range from 0.3 MeV up to 3 MeV. A twin Frisch-grid ionization chamber has been used in a back-to-back configuration as fission-fragment detector. The 242Pu(n ,f ) cross section has been normalized to three different isotopes: 237Np(n ,f ) , 235U(n ,f ) , and 238U(n ,f ) . A comprehensive study of the corrections applied to the data and the uncertainties associated is given. The results obtained are in agreement with previous experimental data at the threshold region up to 0.8 MeV. The resonance-like structure at 0.8 to 1.1 MeV, visible in the evaluations and in most previous experimental values, was not reproduced with the same intensity in this experiment. For neutron energies higher than 1.1 MeV, the results of this experiment are slightly lower than the Evaluated Nuclear Data File/B-VII.1 evaluation but in agreement with the experiment of Tovesson et al. (2009) as well as Staples and Morley (1998). Finally, for energies above 1.5 MeV, the results show consistency with the present evaluations.

  13. Investigation of the chemical explosion of an ion exchange resin column and resulting americium contamination of personnel in the 242-Z building, August 30, 1976

    Energy Technology Data Exchange (ETDEWEB)

    1976-10-19

    As a result of an explosion in the Waste Treatment Facility, 242-Z Building, 200 West Area of the Hanford Reservation on August 30, 1976, the Manager of the Richland Operations Office (RL), Energy Research and Development Administration (ERDA), appointed an ERDA Committee to conduct a formal investigation and to prepare a report on their findings of this occurrence. The Committee was instructed to conduct the investigation in accordance with ERDAMC 0502, insofar as circumstances would permit, to cover and explain technical elements of the casual sequence(s) of the occurrence, and to describe management systems which should have or could have prevented the occurrence. This report is the result of the investigation and presents the conclusions of the review.

  14. Angular distributions of low-spin states in {sup 240}Pu by means of the {sup 242}Pu(p,t){sup 240}Pu reaction

    Energy Technology Data Exchange (ETDEWEB)

    Spieker, Mark; Endres, Janis; Pascu, Sorin; Zilges, Andreas [Koeln Univ. (Germany). Inst. fuer Kernphysik; Bucurescu, Dorel; Zamfir, Nicolae-Victor [Horia Hulubei National Institute of Physics and Nuclear Engineering, Bucharest (Romania); Faestermann, Thomas [Physik Department, Technische Universitaet Muenchen (Germany); Hertenberger, Ralf; Wirth, Hans-Friedrich [Fakultaet fuer Physik, Ludwig-Maximilians-Universitaet Muenchen (Germany)

    2013-07-01

    Since recent experimental and theoretical studies revealed the importance of octupole correlations in the actinide region and especially in {sup 240}Pu, a {sup 242}Pu(p,t){sup 240}Pu experiment has been conducted at the Q3D magnetic spectrograph of the Maier-Leibnitz laboratory in Munich. Excited states in {sup 240}Pu were investigated up to an excitation energy of 3 MeV. Angular distributions have been measured at 9 laboratory angles between 5 {sup circle} and 40 {sup circle}. The comparison of the experimental angular distributions with DWBA calculations allowed the assignment of several low-spin states. Most of them were seen for the first time. The experimental data, especially the data on the 21 J{sup π}= 0{sup +} states, are presented and discussed in the framework of the spdf-version of the Interacting Boson Model.

  15. Antihyperglycemic and antihyperlipidemic activities of 2-(4-[(2-hydroxybenzyl) amino]-phenyl amino-methyl)-phenol in STZ induced diabetic rats.

    Science.gov (United States)

    Sirasanagandla, Swapna; Kasetti, Ramesh Babu; Shaik, Abdul Nabi; Natava, Rajesh; Surtineni, Venkata Prasad; Cirradur, Suresh Reddy; Chippada, Apparao

    2013-08-01

    Oral administration of 2-(4-[(2-hydroxybenzyl) amino]-phenyl amino-methyl)-phenol (HBPMP) (30 mg/kg) to Streptozotocin (STZ) rats produced significant antidiabetic activity after 6 h of HBPMP administration. Treatment of the STZ rats with HBPMP (30 mg/kg/day) for 30 days resulted in a significant decrease in their Fasting Blood Glucose (FBG), Serum Total Cholesterol (TC), Low Density Lipoprotein-Cholesterol (LDL-C), Very Low Density Lipoprotein-Cholesterol (VLDL-C) and triglycerides (TG) along with an increase in serum High Density Lipoprotein-Cholesterol (HDL-C) levels. Activities of Serum Aspartate transaminase (AST), Alanine transaminase (ALT) and Alkaline phosphatase (ALP) and levels of blood urea and creatinine were improved to near normal levels in the treated STZ rats indicating the protective role of the HBPMP against liver and kidney damage and its non-toxic property. In conclusion, HBPMP possesses antihyperglycemic and antihyperlipidemic activities.

  16. Mapeamento Genético do locus 1q 24.2 1q31.3 em famílias segregando periodontite agressiva

    OpenAIRE

    2009-01-01

    Um estudo sugere que o fenótipo da periodontite agressiva localizada está ligado a região 1q25. O objetivo do presente estudo foi aperfeiçoar o mapeamento genético da periodontite agressiva na região cromossômica supracitada em famílias clinicamente bem caracterizadas segregando a doença. A hipótese deste estudo é que variações genéticas localizadas no cromossomo 1 entre as regiões 1q 24.2 e 1q 31.3 contribuem para o fenótipo da periodontite agressiva. Como objetivos específicos, determinamos...

  17. Paired observation of californium-252 neutron intraluminal brachytherapy combined with external-beam radiotherapy with and without lead shielding for cervical cancer%252 Cf中子腔内照射结合挡铅与不挡铅外照射治疗宫颈癌的配对观察

    Institute of Scientific and Technical Information of China (English)

    戴卓捷; 雷新; 陈永红; 刘佳

    2015-01-01

    目的:比较252 Cf中子腔内照射结合挡铅盆腔对穿野和不挡铅箱式四野外照射治疗宫颈癌的治疗结果。方法2004—2007年本院收治的Ⅱa—Ⅲb 期的宫颈鳞癌患者,按照临床分期、年龄、肿瘤大小、贫血程度为配对条件,共筛选出26对(52例)研究对象,分为挡铅盆腔对穿野组(挡铅组)和不挡铅箱式四野组(不挡铅组)。两组患者外照射期间穿插252 Cf中子后装治疗。 Kaplan?Meier法计算5年LC、OS、DFS 并 Logrank 检验差异,晚期并发症发生率差异行 McNemar 法检验。结果挡铅、不挡铅组5年LC 率分别为85%、81%(P=0??014),OS 率分别为89%、73%(P=0??013),DFS 率分别为89%、73%(P=0??013),晚期并发症发生率分别为12%、23%(P=0??008)。结论腔内照射结合外照射治疗宫颈癌时无论采取对穿野还是箱式四野,后程前后野中央均应挡铅。%Objective To compare the efficacy between californium?252 ( 252 Cf ) neutron intraluminal brachytherapy combined with external?beam radiotherapy with lead?shielding pelvic parallel opposing field technique and non?lead?shielding four?field box technique for cervical cancer. Methods A total of 52 patients with stage Ⅱa?Ⅲb cervical squamous cell carcinoma who were admitted to our hospital from 2004 to 2007 were enrolled as subjects and paired by clinical stage, age, tumor size, and degree of anemia. The 26 pairs of patients were divided into lead?shielding pelvic parallel opposing field group (lead?shielding group) and non?lead?shielding four?field box group (non?lead?shielding group). For all patients in both groups, 252 Cf neutron brachytherapy was added in external?beam radiotherapy. The local control (LC), overall survival (OS), and disease?free survival (DFS) rates were calculated using the Kaplan?Meier method and analyzed using the log?rank test. The difference in the incidence of late complications was

  18. Deep VLT spectroscopy of the z=2.49 Radio Galaxy MRC 2104-242 Evidence for a metallicity gradient in its extended emission line region

    CERN Document Server

    Overzier, R; Kurk, J D; De Breuck, C

    2001-01-01

    We present spectroscopic observations of the rest-frame UV line emission around radio galaxy MRC 2104-242 at z=2.49, obtained with FORS1 on VLT Antu. The morphology of the halo is dominated by two spatially resolved regions. Lya is extended by >12 arcsec along the radio axis, CIV and HeII are extended by ~8 arcsec. The overall spectrum is typical for that of high redshift radio galaxies. The most striking spatial variation is that NV is present in the spectrum of the region associated with the center of the galaxy hosting the radio source, the northern region, while absent in the southern region. Assuming that the gas is photoionized by a hidden quasar, the difference in NV emission can be explained by a metallicity gradient within the halo. This is consistent with a scenario in which the gas is associated with a massive cooling flow or originates from the debris of the merging of two or more galaxies.

  19. Computational Thermodynamic Modeling of Hot Corrosion of Alloys Haynes 242 and HastelloyTM N for Molten Salt Service in Advanced High Temperature Reactors

    Energy Technology Data Exchange (ETDEWEB)

    V. Glazoff, Michael; Charit, Indrajt; Sabharwall, Piyush

    2014-09-17

    An evaluation of thermodynamic aspects of hot corrosion of the superalloys Haynes 242 and HastelloyTM N in the eutectic mixtures of KF and ZrF4 is carried out for development of Advanced High Temperature Reactor (AHTR). This work models the behavior of several superalloys, potential candidates for the AHTR, using computational thermodynamics tool (ThermoCalc), leading to the development of thermodynamic description of the molten salt eutectic mixtures, and on that basis, mechanistic prediction of hot corrosion. The results from these studies indicated that the principal mechanism of hot corrosion was associated with chromium leaching for all of the superalloys described above. However, HastelloyTM N displayed the best hot corrosion performance. This was not surprising given it was developed originally to withstand the harsh conditions of molten salt environment. However, the results obtained in this study provided confidence in the employed methods of computational thermodynamics and could be further used for future alloy design efforts. Finally, several potential solutions to mitigate hot corrosion were proposed for further exploration, including coating development and controlled scaling of intermediate compounds in the KF-ZrF4 system.

  20. The production of {sup 238-242}Pu(n,γ){sup 239-243}Pu fissionable fluids in a fusion-fission hybrid reactor

    Energy Technology Data Exchange (ETDEWEB)

    Guenay, Mehtap [Inoenue Univ., Malatya (Turkey). Physics Dept.

    2014-03-15

    In this study, the effect of spent fuel grade plutonium content on {sup 239-243}Pu was investigated in a designed hybrid reactor system. In this system, the fluids were composed of a molten salt, heavy metal mixture with increased mole fractions 99-95 % Li{sub 20}Sn{sub 80}-1-5 % SFG-Pu, 99-95 % Li{sub 20}Sn{sub 80}-1-5 % SFG-PuF{sub 4}, 99-95 % Li{sub 20}Sn{sub 80}-1-5 % SFG-PuO{sub 2}. Beryllium (Be) is a neutron multiplier by (n,2n) reactions. Thence, a Be zone of 3 cm thickness was used in order to contribute to fissile fuel breeding between the liquid first wall and a 9Cr2WVTa ferritic steel blanket which is used as structural material. The production of {sup 238-242}Pu(n,γ){sup 239-243}Pu was calculated in liquid first wall, blanket and shielding zones. Three-dimensional nucleonic calculations were performed by using the most recent version MCNPX-2.7.0 Monte Carlo code and nuclear data library ENDF/B-VII.0. (orig.)

  1. 血清CEA、CA-125、CA-153、CA-199、CA242联合检测对消化道肿瘤诊断的临床意义

    Institute of Scientific and Technical Information of China (English)

    杨德辉; 周力; 张永宏; 张澜林; 谭玉洁; 王焰; 秦雯

    2006-01-01

    目的:探讨血清CEA、CA-125、CA-153、CA-199、CA242联合检测对消化道肿瘤诊断的临床意义。方法:采用酶联免疫吸附法(ELISA法)检测130例恶性消化道肿瘤患者(食管癌32例、胃癌34例、胰腺癌30例、大肠癌34例)血清CEA、CA-125、CA-153、CA-199、CA242水平。结果:表明上述四种消化道肿瘤的血清CEA、CA-125、CA-153、CA-199、CA242与对照组比较结果统计学上均有显著性差异(P〈0.01)。除胰腺癌之外,其余3种消化道肿瘤五项肿瘤标记物联合检测的阳性率均显著高于单一标志物检测(P〈0.05),分别为食管癌62.5%、胃癌85.2%、大肠癌82.3%。结论:血清CEA、CA-125、CA-153、CA-199、CA242联合检测可以显著提高消化道恶性肿瘤诊断的敏感性。

  2. CHLOROPHYLL A, growth rate and graze rate (or grazing rate) site samples data collected in the Gulf of Alaska on the ALPHA HELIX cruises HX242, HX244 and others as part of the NEP project from 2001-04-18 to 2003-08-10 (NODC Accession 0114241)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0114241 includes site samples and biological data collected aboard the ALPHA HELIX during cruises HX242, HX244, HX247, HX271 and HX275 in the Gulf of...

  3. SALINITY, WATER TEMPERATURE, FLUORESCENCE, PHOTOSYNTHETIC ACTIVE RADIATION (PAR) and other profile data collected in the Gulf of Alaska on the ALPHA HELIX cruises HX242, HX244 and others as part of the NEP project from 2001-04-18 to 2003-08-11 (NODC Accession 0115255)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0115255 includes profile, biological and physical data collected aboard the ALPHA HELIX during cruises HX242, HX244, HX247, HX271 and HX275 in the...

  4. SILICATE, WATER TEMPERATURE, FLUORESCENCE, PHOTOSYNTHETIC ACTIVE RADIATION (PAR) and other profile and discrete sample data collected in the Gulf of Alaska on the ALPHA HELIX cruises HX242, HX244 and others as part of the NEP project from 2001-04-18 to 2003-08-11 (NODC Accession 0113348)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113348 includes profile, discrete sample, biological, chemical and physical data collected aboard the ALPHA HELIX during cruises HX242, HX244, HX247,...

  5. Oxidative DNA damage induced by HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid) buffer in the presence of Au(III).

    Science.gov (United States)

    Habib, Ahsan; Tabata, Masaaki

    2004-11-01

    Oxidative DNA damage was investigated by free radicals generated from HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid) buffer, which is widely used in biochemical or biological studies, in the presence of Au(III). The effect of free radicals on the DNA damage was ascertained by gel electrophoresis, electron spin resonance (ESR) spectroscopy and circular dichroism (CD) spectroscopy. ESR results indicated the generation of nitrogen-centered cationic free radicals from the HEPES in the presence of Au(III) which cause the DNA damage. No ESR spectra were observed for phosphate, tris(hydroxymethyl)aminomethane (Tris-HCl) and acetate buffers in the presence of Au(III) or for HEPES buffer in the presence of other metal ions such as Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Pd(II) or [Au(III)(TMPyP)](5+) and [Pd(II)(TMPyP)](4+), where [H(2)(TMPyP)](4+) denotes tetrakis(1-methylpyridium-4-yl)porphyrin. Consequently, no DNA damage was observed for these buffer agents (e.g., phosphate, Tris-HCl or acetate) in the presence of Au(III) or for HEPES in the presence of other metal ions or the metalloporphyrins mentioned above. No detectable inhibitory effect on the DNA damage was observed by using the typical scavengers of reactive oxygen species (ROS) ()OH, O(2)(-) and H(2)O(2). This non-inhibitory effect indicated that no reactive oxygen species were generated during the incubation of DNA with HEPES and Au(III). The drastic change in CD spectra from positive ellipticity to negative ellipticity approximately at 270 nm with increasing concentration of Au(III) also indicated the significant damage of DNA. Only HEPES or Au(III) itself did not damage DNA. A mechanism for the damaging of DNA is proposed.

  6. Measurements of the neutron-induced fission cross sections of /sup 240/Pu and /sup 242/Pu relative to /sup 235/U. [0. 02 to 30 MeV, tables

    Energy Technology Data Exchange (ETDEWEB)

    Behrens, J. W.; Browne, J. C.; Carlson, G. W.

    1976-03-01

    A continuation is given of the fission-cross-section ratio measurements in progress at the Lawrence Livermore Laboratory. Preliminary results are provided for the /sup 240/Pu//sup 235/U and /sup 242/Pu//sup 235/U ratios from 0.02 to 30 MeV and 0.1 to 30 MeV, respectively. Using the threshold-cross-section method, the ratios were normalized to the values 1.368 +- 0.030 and 1.116 +- 0.025, respectively, from 1.75 to 4.00 MeV.

  7. Measurement of the Neutron Capture Cross Sections of $^{233}$U, $^{237}$Np, $^{240,242}$Pu, $^{241,243}$Am and $^{245}$Cm with a Total Absorption Calorimeter at n_TOF

    CERN Multimedia

    Beer, H; Wiescher, M; Cox, J; Rapp, W; Embid, M; Dababneh, S

    2002-01-01

    Accurate and reliable neutron capture cross section data for actinides are necessary for the poper design, safety regulation and precise performance assessment of transmutation devices such as Fast Critical Reactors or Accelerator Driven Systems (ADS). The goal of this proposal is the measurement of the neutron capture cross sections of $^{233}$U, $^{237}$Np, $^{240,242}$Pu, $^{241,243}$Am and $^{245}$Cm at n_TOF with an accuracy of 5~\\%. $^{233}$U plays an essential role in the Th fuel cycle, which has been proposed as a safer and cleaner alternative to the U fuel cycle. The capture cross sections of $^{237}$Np,$^{240,242}$Pu, $^{241,243}$Am and $^{245}$Cm play a key role in the design and optimization of a strategy for the Nuclear Waste Transmutation. A high accuracy can be achieved at n_TOF in such measurements due to a combination of features unique in the world: high instantaneous neutron fluence and excellent energy resolution of the facility, innovative Data Acquisition System based on flash ADCs and t...

  8. Association study of C936T polymorphism of the VEGF gene and the C242T polymorphism of the p22phox gene with diabetes mellitus type 2 and distal diabetic polyneuropathy.

    Science.gov (United States)

    Ghisleni, Melissa Mottin; Biolchi, Vanderlei; Jordon, Bruna Cristina; Rempel, Claudete; Genro, Júlia Pasqualini; Pozzobon, Adriane

    2015-09-01

    Even with long‑term glycemic control, diabetes mellitus type 2 (DM2) remains the predominant cause of diabetic neuropathy. Single nucleotide polymorphism (SNP) C936T of the vascular endothelial growth factor (VEGF) gene and the SNP C242T of the p22phox (CYBA) gene have been investigated in relation to DM2 and its complications. The aim of the present study was to investigate the association between these two SNPs and DM2, and also between the SNPs and the signs and symptoms of diabetic distal polyneuropathy. The DM2 group consisted of 98 individuals and the control group consisted of 104 individuals. The results demonstrated that there was no association between the different genotypes or alleles and increased risk of the disease (P>0.05). With SNP C242T, a significant association with body mass index between the CTxTT genotypes (P=0.043) was identified; and the greatest body mass indexes were among individuals with the TT genotype. An association between the degree of neuropathic symptoms and genotypic/allelic distribution of these polymorphisms was not observed. In conclusion, the investigated polymorphisms are not correlated with the risk of developing DM2.

  9. 242例子宫内膜异位症患者腹腔镜检病灶特点与盆腔疼痛相关性分析%Retrospective analysis of the relation between the pelvic pain and the lesion features in 242 patients with en-dometriosis

    Institute of Scientific and Technical Information of China (English)

    陈素芬; 彭丽娟; 刘久英

    2015-01-01

    目的:探讨子宫内膜异位症患者腹腔镜检病灶特点与盆腔疼痛的相关性。方法:分析2009年2月至2014 年2月于我院诊治的242例子宫内膜异位症的临床资料,记录患者手术前盆腔疼痛的性质和程度及患者术中所见的病变部位、类型、浸润深度及粘连程度,分析盆腔疼痛与腹腔镜检病灶特点的相关性。结果:(1)34例为单纯子宫内膜异位囊肿的患者无盆腔疼痛,208例为子宫内膜异位囊肿合并盆腔粘连、深部浸润及腹膜病灶的患者,均有不同程度的盆腔疼痛。(2)手术所见病变位于子宫直肠凹者81例,位于子宫骶韧带者73例,位于阔韧带者74例,位于输卵管与子宫表面者45例,位于输卵管与反折腹膜者18例。其中,病变位于子宫直肠凹及子宫骶韧带者盆腔疼痛发生率显著高于病变位于其它部位的患者(P <0.05)。(3)轻度盆腔粘连66例,中重度粘连142例,中重度粘连患者的盆腔疼痛发生率明显高于轻度粘连者(P <0.05)。(4)64例为浅表型浸润(深度<5mm),144例为深部型浸润(深度≥5mm),深部型浸润患者盆腔疼痛发生率明显高于浅表型浸润患者(P <0.05)。结论:子宫内膜异位症患者盆腔疼痛与腹腔镜检所见病灶的特点关系密切,盆腔粘连、深部浸润、骶韧带及子宫直肠凹部位病变等为盆腔疼痛的重要相关因素。%Objectives:To investigate the relation between the pelvic pain and the lesion features in pa-tients with endometriosis.Methods:242 patients with endometriosis from February 2009 to May 2014 in our hospi-tal were analyzed retrospectively.The characters of pelvic pain and the lesion features such as location,type,depth and adhesion degree were all recorded.The relation between the pelvic pain and the lesion features was analyzed. Results:① In 242 cases of endometriosis,the pelvic pain was not found in 34

  10. Octa­butyl­bis{(E)-2-[4-(2-hydroxy­benzyl­ideneamino)phen­yl]acetato}di-μ2-methoxo-di-μ3-oxido-tetra­tin(IV)

    OpenAIRE

    Li, Wenkuan; Yin, Handong; Wen, Liyuan; Wang, Daqi; Fan, Weidong

    2009-01-01

    The title compound, [Sn4(C4H9)8(C15H12NO3)2(CH3O)2O2], is a centrosymmetric dimer and displays a ladder type structural motif. There are four SnIV centres which can be divided into two sorts, viz. two endocyclic and two exocyclic. The endo- and exocyclic SnIV centres are linked by bidentate deprotonated methanol and μ3-O atoms. Each exocyclic SnIV centre is also coordinated by a monodentate 2-[4-(2-hydroxy­benzyl­idene­amino)phen­yl]acetate ligand. Parts of the butyl groups were found to be d...

  11. Microwave-Assisted Solution Phase Synthesis of Novel 2-{4-[2-(N-Methyl-2-pyridylaminoethoxy]phenyl}-5-Substituted 1,3,4-Oxadiazole  Library

    Directory of Open Access Journals (Sweden)

    Santosh L. Gaonkar

    2011-01-01

    Full Text Available A new series of 2-{4-[2-(N-methyl-2-pyridylaminoethoxy]phenyl}-5-substituted 1,3,4-oxadiazoles were synthesized by the oxidative cyclization of hydrazones derived from 4-[2-(methylpyridin-2-ylaminoethoxy]benzaldehyde and aryl hydrazines using chloramine-T as an efficient catalyst. All steps were assisted by microwave irradiation. Microwave enables all these reactions to be simple, rapid, high yielding, and avoid chromatograph purification and led environmentally benign total synthesis of focused oxadiazole library. All the synthesized compounds were isolated in good yield and characterized by 1H NMR, 13C NMR, and elemental analyses. The title compounds represent a novel class of biologically active heterocycles.

  12. Effect of (3,5,6-trimethylpyrazin-2-yl)methyl 2-[4-(2-methylpropyl)phenyl]propanoate (ITE), a newly developed anti-inflammatory drug, on type II collagen-induced arthritis in mice.

    Science.gov (United States)

    Ma, Tao; Cao, Ying-Lin; Xu, Bei-Bei; Zhou, Xiao-Mian

    2004-06-01

    The effect of (3,5,6-trimethylpyrazin-2-yl)methyl 2-[4-(2-methylpropyl)phenyl]propanoate (ITE) on type II collagen (CII)-induced arthritis in mice was studied. Mice were immunized twice with CII, ITE being given orally once a day for 40 d after the 1st immunization. Clinical assessment showed that ITE had no effect on the day of onset of arthritis but did lowered the incidence rate of arthritis and the arthritis score. And ITE had a marked suppressive effect on the mouse hind paw edema induced by CII. ITE suppressed the delayed-type mouse ear skin reaction to CII but had no effect on the level of serum anti-CII antibodies. These results suggest that ITE inhibits the development of CII-induced arthritis in mice by suppressing delayed-type hypersensitivity to CII.

  13. Prevalência e padrão de distribuição das doenças cerebrovasculares em 242 idosos, procedentes de um hospital geral, necropsiados em Belo Horizonte, Minas Gerais, no período de 1976 a 1997 Prevalence and types of cerebrovascular diseases in 242 hospitalized elderly patients, autopsied in Belo Horizonte, Minas Gerais, Brazil, from 1976 to 1997

    Directory of Open Access Journals (Sweden)

    José Eymard H. Pittella

    2002-03-01

    Full Text Available OBJETIVO: Descrever a prevalência e os tipos das doenças cerebrovasculares (DCVs em indivíduos idosos necropsiados. MÉTODO: Foram consultados os laudos neuropatológicos de 242 pacientes com idade igual ou superior a 61 anos, procedentes em sua maioria do Hospital das Clínicas da Universidade Federal de Minas Gerais, em Belo Horizonte, Minas Gerais, e necropsiados consecutivamente no período 1976 a 1997. RESULTADO: Os principais grupos de doenças do sistema nervoso central (SNC foram representados por DCVs (71,9%, infecções (12,4%, neoplasias (7,1%, traumatismos crânio-encefálicos (3,7%, doenças nutricionais (2,5% e doenças degenerativas (1,7%. As DCVs mais frequentes foram: aterosclerose (61,2%, doença cerebrovascular hipertensiva (25,6% e infarto cerebral (14,9%. Observou-se aumento da frequência e da gravidade da aterosclerose e da frequência da doença cerebrovascular hipertensiva com o avançar da idade. Houve associação significativa entre doença cerebrovascular hipertensiva e aterosclerose. As DCVs foram clinicamente sintomáticas e as responsáveis diretas pelo óbito em 42,7% e 17,3% dos pacientes, respectivamente. CONCLUSÃO: As DCVs constituíram o principal grupo de doenças do SNC no idoso. A aterosclerose e a doença cerebrovascular hipertensiva foram as principais doenças deste grupo, notando-se aumento de sua frequência com o avançar da idade e associação significativa entre ambas.OBJECTIVE: To describe the prevalence and the types of cerebrovascular diseases (CVDs in autopsied elderly individuals. METHOD: Consecutive clinical charts and neuropathological reports of 242 patients aged 61 years or older were reviewed. The patients died in Hospital das Clínicas, Federal University of Minas Gerais, in Belo Horizonte, Minas Gerais, Brazil, from 1976 to 1997. RESULTS: The prevalent diseases of the central nervous system (CNS found in decreasing order were: CVDs (71.9%, infections (12.4%, neoplasms (7.1%, head

  14. 32 CFR 242.5 - Admission procedures.

    Science.gov (United States)

    2010-07-01

    ..., Attn: Assistant Dean for Academic Support. The School of Medicine shall not process a military person's...) MISCELLANEOUS ADMISSION POLICIES AND PROCEDURES FOR THE SCHOOL OF MEDICINE, UNIFORMED SERVICES UNIVERSITY OF THE... to the School of Medicine shall make direct application following instructions published in...

  15. 48 CFR 242.7203 - Review procedures.

    Science.gov (United States)

    2010-10-01

    ... full advantage of the day-to-day work done by both organizations. (3) Prepare the MMAS report. (d... to be reviewed. In addition, they must— (1) Conduct reviews as a team effort. (i) the ACO— (A) Appoints a team leader; and (B) Ensures that the team includes appropriate functional specialists...

  16. Reference: 242 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available iro et al. 2005 Dec. Planta 222(6):1001-9. For plant salt tolerance, it is important to regulate the uptake ...and accumulation of Na+ ions. The yeast pmp3 mutant which lacks PMP3 gene accumulates excess Na+ ions in the cell and shows incre...ully understood, it is proposed that PMP3 contributes to the restriction of Na+ uptake and consequently salt...) Heynh.) plants; and to thereby indicate the physiological role of RCI2A in higher plants. Two T-DNA insert...ional mutants of RCI2A were identified. Although the growth of rci2a mutants was comparable with that of wil

  17. 36 CFR 242.4 - Definitions.

    Science.gov (United States)

    2010-07-01

    ..., not otherwise prohibited by Federal law or regulation, to support personal and family needs; and does not include trade which constitutes a significant commercial enterprise. Customary and traditional use... 5 U.S.C. Appendix II, 1-15). Family means all persons related by blood, marriage, or adoption or...

  18. 24 CFR 242.54 - Nondiscrimination.

    Science.gov (United States)

    2010-04-01

    ... and sex discrimination do not affect the eligibility of hospitals for women and children. ... financed with mortgages insured under this part must be made available without discrimination as to...

  19. 17 CFR 242.500 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... maintains and enforces written policies and procedures reasonably designed to prevent the broker or dealer...) the term: Covered person of a broker or dealer means an associated person of that broker or dealer but... performing similar functions) or employees in common with the broker or dealer who can influence...

  20. 32 CFR 242.3 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... ADMISSION POLICIES AND PROCEDURES FOR THE SCHOOL OF MEDICINE, UNIFORMED SERVICES UNIVERSITY OF THE HEALTH... advanced (junior-senior level) nonscholarship ROTC. (4) Individuals in attendance at any of the three.... Means the Medical School program of the Uniformed Services University of the Health Sciences. (e)...

  1. 24 CFR 242.16 - Applications.

    Science.gov (United States)

    2010-04-01

    ..., Critical Access Hospital, or rural referral center; (D) Community-wide use rates (discharges and days/1000... area; (O) Planned construction at other facilities in the region; (P) Historical market share by major... with guidance that shall be provided in written directives by HUD. In any event, HUD shall not issue...

  2. 17 CFR 242.300 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Ats... or more of the capital of the alternative trading system. (g) NMS stock shall have the meaning... NMS stock for purposes of this Regulation ATS. (h) Effective transaction reporting plan shall have...

  3. 24 CFR 242.1 - Definitions.

    Science.gov (United States)

    2010-04-01

    ..., supplies, tools, books, records (whether in written or electronic form), computer equipment (hardware and..., specifications, and contracts for architectural, engineering, and construction services relating to the land...

  4. 27 CFR 25.242 - Markings.

    Science.gov (United States)

    2010-04-01

    ... type, in the same color of ink, and on the same background. (b) Barrels and kegs. A brewer may remove cereal beverage in barrels and kegs if the sides are durably painted at each end with a white stripe not less than 4 inches in width and the heads are painted in a solid color, with conspicuous lettering in...

  5. 19 CFR 10.242 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... fabric(s), means that all of the production processes, starting with polymers, fibers, filaments, textile..., starting with the extrusion of filament, strip, film, or sheet and including drawing to fully orient...

  6. 2-[4-(2-Formylphenoxybutoxy]benzaldehyde

    Directory of Open Access Journals (Sweden)

    Aliakbar Dehno Khalaji

    2011-09-01

    Full Text Available In the crystal structure of the title compound, C18H18O4, the full molecule is generated by the application of an inversion centre. The molecule is essentially planar, with an r.m.s. deviation of 0.017 (1 Å for all non-H atoms. The molecules are linked through intermolecular C—H...O interactions to form a molecular sheet parallel to the (overline{1}02 plane.

  7. Time Series Analysis For The Californium Source In Sudbury Neutrino Observatory

    CERN Document Server

    Labranche, H

    2004-01-01

    The Sudbury Neutrino Observatory uses a 252Cf source to measure the neutron detection efficiency of its detector. We propose a method, the Time Series Analysis, that uses pairs of time intervals between the detected events to find the neutron detection efficiency, the probability to detect from a fission the prompt γ-rays, the neutron mean life inside the detector, the source fission rate and the residual activity rate from non-fission events. We explain our theoretical model of the source and the procedure to fit the data. With a 2.5 MeV threshold cut on the data, the neutron mean life is 5.281 ± 0.004(stat) msec and the source fission rate at June 12, 2001 is 4.360 ± 0.004(stat) sec −1. At this moment, the Time Series can only be applied to data when the source is near the centre. The technique is also applied with an AmBe source. We also show the latest progress to improve the technique. Finally, we briefly show another method, the Multiplicity Analysis, which was ...

  8. Design and Potentials of the Californium-252 Radiation Facility at WES

    Science.gov (United States)

    1975-09-01

    standards, using an Image Quality Indicator (IQI) and also a Beam Purity Indicator (BPI),** shows a relatively good thermal and epithermal neutron ...colli-nated beam of the desired neutron radiation. Consideration of the basic nuclear properties was therefore a necessity in achieving the desired...The upper 6 ft has been designed for use in radiography and neutron counting. The steel tank was prefabricated in two sections. The lower 6-ft

  9. Design of a californium-based epithermal neutron beam for neutron capture therapy.

    Science.gov (United States)

    Yanch, J C; Kim, J K; Wilson, M J

    1993-08-01

    The potential of the spontaneously fissioning isotope, 252Cf, to provide epithermal neutrons for use in boron neutron capture therapy (BNCT) has been investigated using Monte Carlo simulation. The Monte Carlo code MCNP was used to design an assembly composed of a 26 cm long, 11 cm radius cylindrical D2O moderator followed by a 64 cm long Al filter. Lithium filters are placed between the moderator and the filter and between the Al and the patient. A reflector surrounding the moderator/filter assembly is required in order to maintain adequate therapy flux at the patient position. An ellipsoidal phantom composed of skull- and brain-equivalent material was used to determine the dosimetric effect of this beam. It was found that both advantage depths and advantage ratios compare very favourably with reactor and accelerator epithermal neutron sources. The dose rate obtainable, on the other hand, is 4.1 RBE cGy min-1, based on a very large (1.0 g) source of 252Cf. This dose rate is two to five times lower than those provided by existing reactor beams and can be viewed as a drawback of using 252Cf as a neutron source. Radioisotope sources, however, do offer the advantage of in-hospital installation.

  10. The clinical analysis about the dilatation for the stoma narrow after operation of carcinoma of esophago cardia%扩张治疗242例食管贲门癌术后吻合口狭窄疗效分析

    Institute of Scientific and Technical Information of China (English)

    林焕雄; 蔡文

    2010-01-01

    目的 总结扩张治疗食管贲门癌术后吻合口狭窄的临床疗效.方法 采用沙氏扩张器治疗242例吻合口狭窄患者.结果 共行扩张治疗647例次,平均2.67次/人.有效率99.1%,痊愈率达87.6%.结论 采用沙氏扩张器是治疗食管贲门癌术后吻合口狭窄一种安全、简便、有效手段之一.%Objective The author summarizes the clinical curative effect about the dilatation for the stoma narrow after operation of carcinoma of esophago cardia. Methods 242 patients included were expanded with Savary-Gilliard dilator. Results 647 expanding therapies were made, average 2.67 times per patient. The effective rate is 99.1%,the recovery rate is 87.6%. Conclusion The dilatation using Savary-Gilliard dilator is one of the safe, convenient, effective methods in the treatment of stoma narrow after operation of carcinoma of esophago cardia.

  11. Two different zinc(II)-aqua complexes held up by a metal-oxide based support: Synthesis, crystal structure and catalytic activity of [HMTAH]2[{Zn(H2O)5}{Zn(H2O)4}{Mo7O24}].2H2O (HMTAH = protonated hexamethylenetetramine)

    Indian Academy of Sciences (India)

    T Arumuganathan; A Srinivasarao; T Vijay Kumar; Samar K Das

    2008-01-01

    An inorganic−organic hybrid material, [HMTAH]2[{Zn(H2O)5}{Zn(H2O)4}{Mo7O24}].2H2O (1) (where HMTAH = protonated hxamethylenetetramine) has been synthesized and structurally characterized. The compound 1 crystallizes in a monoclinic space group 2/. The crystal data of 1: = 43.12(3), = 12.399(10), = 16.285(13), = 111.131(11), = 8. Its crystal structure shows that two different Zn(II)-aqua complexes, [Zn(H2O)5]2+ and [Zn(H2O)4]2+ are covalently coordinated to a heptamolybdateanion [Mo7O24]6- resulting in an anionic species of polyoxometalate supported zinc-aqua complexes, [{Zn(H2O)}{Zn(H2O)4}{Mo7O24}]2-, that is stabilized with two protonated hexamethylenetetramine cations in the title compound 1. In the crystal structure, both lattice water molecules are found to interact with the heptamolybdate cluster anion and the protonated hexamethylenetetramine cation resulting in an intricate three-dimensional hydrogen bonding network. Interestingly, compound 1 exhibits catalytic activity towards oxidation of some primary alcohols.

  12. Simultaneous measurement of {sup 239}Pu, {sup 240}Pu, {sup 241}Pu, and {sup 242}Pu by high resolution inductively coupled plasma mass spectrometer (HR ICP-MS) in marine sediments; Mesure des isotopes du plutonium des sediments marins par spectrometrie de masse a plasma couple inductivement haute resolution (HR ICP-MS)

    Energy Technology Data Exchange (ETDEWEB)

    Bruneau, F

    1999-07-01

    Transuranics elements are of particular interest in radioecological studies because of their radiotoxicity and their potential use to decipher source fingerprints and transport processes. The simultaneous measurement of {sup 239}Pu, {sup 240}Pu, {sup 241}Pu, and {sup 242}Pu in environmental samples requires a specific chemical procedure. This work deals with an analytical procedure which yields a very high grade of purification of Pu suitable for ultra low level detection by HR ICP-MS, from marine sediments. After the elimination of major elements (Fe, Al, Mg...) by a first chromatographic separation, a new device of purification by solvent extraction and concentration by a second chromatographic separation is used to obtain a concentrated and high purified solution of plutonium. The chemical procedure have been validated on IAEA certified sediment samples and on sediment samples collected in the roads of Cherbourg which had been previously analysed by other techniques (a spectrometry and thermo-ionisation mass spectrometer). (author)

  13. Determination of the optimum-size californium-252 neutron source for borehole capture gamma-ray analysis

    Science.gov (United States)

    Senftle, F.E.; Macy, R.J.; Mikesell, J.L.

    1979-01-01

    The fast- and thermal-neutron fluence rates from a 3.7 ??g 252Cf neutron source in a simulated borehole have been measured as a function of the source-to-detector distance using air, water, coal, iron ore-concrete mix, and dry sand as borehole media. Gamma-ray intensity measurements were made for specific spectral lines at low and high energies for the same range of source-to-detector distances in the iron ore-concrete mix and in coal. Integral gamma-ray counts across the entire spectrum were also made at each source-to-detector distance. From these data, the specific neutron-damage rate, and the critical count-rate criteria, we show that in an iron ore-concrete mix (low hydrogen concentration), 252Cf neutron sources of 2-40 ??g are suitable. The source size required for optimum gamma-ray sensitivity depends on the energy of the gamma ray being measured. In a hydrogeneous medium such as coal, similar measurements were made. The results show that sources from 2 to 20 ??g are suitable to obtain the highest gamma-ray sensitivity, again depending on the energy of the gamma ray being measured. In a hydrogeneous medium, significant improvement in sensitivity can be achieved by using faster electronics; in iron ore, it cannot. ?? 1979 North-Holland Publishing Co.

  14. Optical transitions in highly charged californium ions with high sensitivity to variation of the fine-structure constant.

    Science.gov (United States)

    Berengut, J C; Dzuba, V A; Flambaum, V V; Ong, A

    2012-08-17

    We study electronic transitions in highly charged Cf ions that are within the frequency range of optical lasers and have very high sensitivity to potential variations in the fine-structure constant, α. The transitions are in the optical range despite the large ionization energies because they lie on the level crossing of the 5f and 6p valence orbitals in the thallium isoelectronic sequence. Cf(16+) is a particularly rich ion, having several narrow lines with properties that minimize certain systematic effects. Cf(16+) has very large nuclear charge and large ionization energy, resulting in the largest α sensitivity seen in atomic systems. The lines include positive and negative shifters.

  15. 32 CFR 242b.7 - Officers of the University.

    Science.gov (United States)

    2010-07-01

    ... Medicine. (v) Associate Dean for Academic Affairs of the School of Medicine. (vi) Associate Dean for... Affairs will report directly to the Dean, School of Medicine. (5) Associate Dean for Academic Affairs of the School of Medicine. (i) The Associate Dean for Academic Affairs will be responsible for...

  16. 48 CFR 3452.242-72 - Withholding of contract payments.

    Science.gov (United States)

    2010-10-01

    ... clause in all solicitations and contacts other than purchase orders: Withholding of Contract Payments... shall promptly notify the contractor of its intention to withhold payment of any invoice or...

  17. 48 CFR 242.302 - Contract administration functions.

    Science.gov (United States)

    2010-10-01

    ... solicitation or award. (S-70) Serve as the single point of contact for all Single Process Initiative (SPI... agreements for SPI processes, when authorized by the affected components. (S-71) DCMA has responsibility...

  18. 36 CFR 242.26 - Subsistence taking of wildlife.

    Science.gov (United States)

    2010-07-01

    ... not possess or transport the hide of a bear that does not have the penis sheath or vaginal orifice... side, or antlers with 2 brow tines on both sides, by State registration permit only Sept.-Oct. 15. Unit... spike-fork or 50-inch antlers or 3 or more brow tines on one side, or antlers with 2 brow tines on...

  19. 48 CFR 1852.242-70 - Technical direction.

    Science.gov (United States)

    2010-10-01

    ... Direction (SEP 1993) (a) Performance of the work under this contract is subject to the written technical..., the fixed fee (if any), or the time required for contract performance; (4) Changes any of the expressed terms, conditions, or specifications of the contract; or (5) Interferes with the...

  20. 40 CFR 52.242 - Disapproved rules and regulations.

    Science.gov (United States)

    2010-07-01

    ... regulations. Link to an amendment published at 75 FR 37730, June 30, 2010. (a) The following Air Pollution... Cellular (Foam) Products,” submitted on March 7, 2008 and adopted on September 7, 2007. (2) Antelope Valley Air Pollution Control District. (i) Rule 118, Emergencies, submitted on March 10, 1998. (3)...

  1. 17 CFR 242.604 - Display of customer limit orders.

    Science.gov (United States)

    2010-04-01

    ... association-sponsored system, or an electronic communications network that complies with the requirements of... responsible broker or dealer, electronic communications network, national securities exchange, or national... interest, the protection of investors and the removal of impediments to and perfection of the mechanism...

  2. 9 CFR 354.242 - Cleaning of equipment and utensils.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION VOLUNTARY INSPECTION OF RABBITS AND EDIBLE PRODUCTS THEREOF Maintenance of... all times. Cleaned equipment and utensils shall be drained on racks and shall not be nested. (i)...

  3. Dicty_cDB: AFH242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CA sequence update 2001. 6. 2 Translated Amino Acid sequence claywvyntvysytsl*rii...r*snsynirslnykwss*nwc*sleelktslpisnklqs Frame C: claywvyntvysytsl*riikknkkkek*vmfmill*ldqvfqv*cvvin*krmdikf*

  4. Preface: phys. stat. sol. (b) 242/9

    Science.gov (United States)

    Sánchez, Maria

    2005-07-01

    The XVII Latin American Symposium on Solid State Physics took place in the conference rooms of the Convent San Francisco de Asis, in the heart of the Old Havana. The sixteen previous editions were organized in eight different countries; the last two were in Colombia (Cartagena, 1999) and Venezuela (Merida, 2002). After eighteen years the meeting came back to Havana in 2004.The program topics included: Surfaces and interfaces analysis; Spintronics; Magnetism; Materials and energy; Ab-initio methods, simulations and modeling in solids; Nanophysics, nanomaterials and nanotechnology; New materials, properties and applications; Preparation of materials, thin films and characterization; High temperature superconductivity; Techniques of structural analysis in solids. The program included 6 plenary talks, 13 invited talks, 58 oral presentations (in eight sessions) and 200 poster contributions (in four poster sessions).The meeting attracted more than 200 participants from 14 countries. The physica status solidi Young Researcher Award sponsored by Wiley-VCH was conferred at the meeting. This prize was divided between two participants: Clara Calderón (Study of electrical transport properties of ZnO thin films used as front contact of solar cells) from Colombia and Aim?? Pelaiz Barranco (AC behavior in lanthanum modified PZT ferroelectric ceramics) from Cuba. Special Mentions went to Val??rie Halté (Femtosec-ond dynamics of transmission of gold arrays of sub-wavelength holes) from France, Erick Larramendi Cancio (Cd desorption induced by Zn exposure during atomic layer epitaxy of CdxZn1-xTe) and Julio Cesar Rimada Herrera (Quantum and conversion efficiency calculation of AlGaAs/GaAs multiple quantum well solar cells) from Cuba.Nanostructures and in general low dimensional physics related to different systems was a very hot topic during the meeting. Some talks and presentations were devoted to optoelectronic materials and devices. Characterization of solids by different structural and optical techniques together with modeling and simulations were also important subjects of the symposium.The XVIII Symposium will be held in Mexico in 2006.The editors wish to thank all the participants who contributed to the success of the meeting and hope that it helped to develop close links between researchers and institutions of Latin America.

  5. Dicty_cDB: SLF242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 64 6e-09 BC127887_1( BC127887 |pid:none) Homo sapiens thyroglobulin, mRNA (... 64 8e-09 AK299197_1( AK299197..._1( AF080484 |pid:none) Homo sapiens thyroglobulin gene, e... 64 8e-09 protein up

  6. 17 CFR 242.100 - Preliminary note; definitions.

    Science.gov (United States)

    2010-04-01

    ... the distribution. (3) In the case of a distribution involving a merger, acquisition, or exchange offer... distribution participant, issuer, or selling security holder in connection with the acquisition or...

  7. Facility effluent monitoring plan for 242-A evaporator facility

    Energy Technology Data Exchange (ETDEWEB)

    Crummel, G.M.; Gustavson, R.D.

    1995-02-01

    A facility effluent monitoring plan is required by the U.S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation showed the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-1. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated, as a minimum, every three years.

  8. 36 CFR 242.27 - Subsistence taking of fish.

    Science.gov (United States)

    2010-07-01

    ... the fish, their parts, or their eggs uses them for personal or family consumption. If you are not a... published open seasons or harvest limits if the harvested fish will be used for food in traditional or.... A qualifying program must have instructors, enrolled students, minimum attendance requirements,...

  9. 36 CFR 242.24 - Customary and traditional use determinations.

    Science.gov (United States)

    2010-07-01

    ... Bay area. Cook Inlet Area Fish other than salmon, Dolly Varden, trout, char, grayling, and burbot... rivers of the Yakutat Area from the Doame River to Point Manby. Dolly Varden, steelhead trout, and smelt... drainage, and south of and including Knight Island. Remainder of the Yakutat Area. Dolly Varden,...

  10. Refractory Metal Liner Processing for M242 Medium Caliber Barrels

    Science.gov (United States)

    2013-01-01

    tapping a hole in the top end of the load rod. 6 3. Liner and Barrel Dimensions Several GLEEM experiments had previously been conducted with a...the load rod had been inserted with tapped end next to the elastomer, which extruded into the hole. During the next pass with the 20-in load rod, the...Load release occurred at a rate of 15 kip/min. The gun tube was then inverted and a fifth pass attempted. For this pass, straps were applied to the

  11. 17 CFR 242.610 - Access to quotations.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms... national securities exchange or national securities association to the quotations in an NMS stock displayed... displays quotations in an NMS stock through an SRO display-only facility shall provide a level and cost...

  12. 17 CFR 242.612 - Minimum pricing increment.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms... display, rank, or accept from any person a bid or offer, an order, or an indication of interest in any NMS... accept from any person a bid or offer, an order, or an indication of interest in any NMS stock priced...

  13. 17 CFR 242.505 - Exclusion for news media.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Ac... registered with the Commission as a broker or dealer or investment adviser. Regulation NMS—Regulation of...

  14. 17 CFR 242.611 - Order protection rule.

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms... NMS stocks that do not fall within an exception set forth in paragraph (b) of this section and, if... bid was priced higher than a protected offer in the NMS stock. (5) The transaction that...

  15. 48 CFR 952.242-70 - Technical direction.

    Science.gov (United States)

    2010-10-01

    ... that assists in interpreting drawings, specifications, or technical portions of the work description. (3) Reviewing and, where required by the contract, approving, technical reports, drawings... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Technical direction....

  16. 7 CFR 2.42 - Administrator, Farm Service Agency.

    Science.gov (United States)

    2010-01-01

    .... 2201 et seq.). (7) Conduct fiscal, accounting and claims functions relating to CCC programs for which...)), with respect to the acquisition of real property and interests in real property required to conduct a... Agricultural Services: (1) Designating counties and areas for emergency programs under Pub. L. No. 85-58,...

  17. Dicty_cDB: VSF242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available .15 1 BF824319 |BF824319.1 NcEST3a21h12.y1 Nc 1314 Tachyzoite cDNA Neospora caninum cDNA 5' similar to TR:Q9...ZNS3 Q9ZNS3 RIBOSOMAL PROTEIN S27. ;, mRNA sequence. 36 0.32 2 BG235080 |BG235080.1 NcEST3a40b01.y1 Nc 1314 Tachyzoite cDNA Neospora...OTEIN S27. ;, mRNA sequence. 36 0.34 2 BF249095 |BF249095.1 NcEST3a07a05.y1 Nc 1314 Tachyzoite cDNA Neospora

  18. 48 CFR 652.242-72 - Shipping Instructions.

    Science.gov (United States)

    2010-10-01

    ... dimensions of lumber for struts, frame members, and single diagonal braces Up to 45 kg 19.05 × 57.15mm 46 to... braced inside the shipping container to prevent the articles from shifting. (c) Packing cases...

  19. Radiative capture on $^{242}$Pu for MOX fuel reactors

    CERN Multimedia

    The use of MOX fuel (mixed-oxide fuel made of UO$_{2}$ and PuO$_{2}$) in nuclear reactors allows substituting a large fraction of the enriched Uranium by Plutonium reprocessed from spent fuel. Indeed around 66% of the plutonium from spent fuel is made of $^{239}$Pu and $^{241}$Pu, which are fissile in thermal reactors. A typical reactor of this type uses a fuel with 7% reprocessed Pu and 93% depleted U, thus profiting from both the spent fuel and the remaining $^{238}$U following the $^{235}$U enrichment. With the use of such new fuel compositions rich in Pu the better knowledge of the capture and fission cross sections of the Pu isotopes becomes very important. This is clearly stated in the recent OECD NEA’s “High Priority Request List” and in the WPEC-26 “Uncertainty and target accuracy assessment for innovative systems using recent covariance data evaluations” report. In particular, a new series of cross section evaluations have been recently carried out jointly by the European (JEFF) and United ...

  20. 10 CFR 72.242 - Recordkeeping and reports.

    Science.gov (United States)

    2010-01-01

    ... NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Approval of... fabrication deficiency affects the ability of structures, systems, and components important to safety...

  1. 1935 15' Quad #242 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  2. Dicty_cDB: VHO242 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available wimonas jakobiformis translati... 189 5e-47 EU812174_1( ... 2008.12. 9 Homology vs Protein Score E Sequences producing significant alignments: (bits) Value DQ295228_1( DQ295228 |pid:none) Mala

  3. 49 CFR 24.2 - Definitions and acronyms.

    Science.gov (United States)

    2010-10-01

    ... system adequate for lighting and other devices; (iii) Contain a heating system capable of sustaining a...; a mobile home; or any other residential unit. (11) Dwelling site. The term dwelling site means a... received or earned by dependent children and full time students under 18 years of age. (See appendix...

  4. 40 CFR 180.242 - Thiabendazole; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ..., dry, seed 0.1 None Beet, sugar, dried pulp 3.5 12/25/10 Beet, sugar, roots 0.25 12/25/10 Beet, sugar... Fruit, citrus, group 10, postharvest 10.0 None Fruit, pome, group 11, postharvest 5.0 None Mango 10.0... Strawberry1 5.0 None Sweet potato (postharvest to sweet potato intended only for use as seed) 0.05 None...

  5. Keno-Nr a Monte Carlo Code Simulating the Californium -252-SOURCE-DRIVEN Noise Analysis Experimental Method for Determining Subcriticality

    Science.gov (United States)

    Ficaro, Edward Patrick

    The ^{252}Cf -source-driven noise analysis (CSDNA) requires the measurement of the cross power spectral density (CPSD) G_ {23}(omega), between a pair of neutron detectors (subscripts 2 and 3) located in or near the fissile assembly, and the CPSDs, G_{12}( omega) and G_{13}( omega), between the neutron detectors and an ionization chamber 1 containing ^{252}Cf also located in or near the fissile assembly. The key advantage of this method is that the subcriticality of the assembly can be obtained from the ratio of spectral densities,{G _sp{12}{*}(omega)G_ {13}(omega)over G_{11 }(omega)G_{23}(omega) },using a point kinetic model formulation which is independent of the detector's properties and a reference measurement. The multigroup, Monte Carlo code, KENO-NR, was developed to eliminate the dependence of the measurement on the point kinetic formulation. This code utilizes time dependent, analog neutron tracking to simulate the experimental method, in addition to the underlying nuclear physics, as closely as possible. From a direct comparison of simulated and measured data, the calculational model and cross sections are validated for the calculation, and KENO-NR can then be rerun to provide a distributed source k_ {eff} calculation. Depending on the fissile assembly, a few hours to a couple of days of computation time are needed for a typical simulation executed on a desktop workstation. In this work, KENO-NR demonstrated the ability to accurately estimate the measured ratio of spectral densities from experiments using capture detectors performed on uranium metal cylinders, a cylindrical tank filled with aqueous uranyl nitrate, and arrays of safe storage bottles filled with uranyl nitrate. Good agreement was also seen between simulated and measured values of the prompt neutron decay constant from the fitted CPSDs. Poor agreement was seen between simulated and measured results using composite ^6Li-glass-plastic scintillators at large subcriticalities for the tank of uranyl nitrate. It is believed that the response of these detectors is not well known and is incorrectly modeled in KENO-NR. In addition to these tests, several benchmark calculations were also performed to provide insight into the properties of the point kinetic formulation.

  6. Accurate determination of Curium and Californium isotopic ratios by inductively coupled plasma quadrupole mass spectrometry (ICP-QMS) in 248Cm samples for transmutation studies

    Energy Technology Data Exchange (ETDEWEB)

    Gourgiotis, A.; Isnard, H.; Aubert, M.; Dupont, E.; AlMahamid, I.; Cassette, P.; Panebianco, S.; Letourneau, A.; Chartier, F.; Tian, G.; Rao, L.; Lukens, W.

    2011-02-01

    The French Atomic Energy Commission has carried out several experiments including the mini-INCA (INcineration of Actinides) project for the study of minor-actinide transmutation processes in high intensity thermal neutron fluxes, in view of proposing solutions to reduce the radiotoxicity of long-lived nuclear wastes. In this context, a Cm sample enriched in {sup 248}Cm ({approx}97 %) was irradiated in thermal neutron flux at the High Flux Reactor (HFR) of the Laue-Langevin Institute (ILL). This work describes a quadrupole ICP-MS (ICP-QMS) analytical procedure for precise and accurate isotopic composition determination of Cm before sample irradiation and of Cm and Cf after sample irradiation. The factors that affect the accuracy and reproducibility of isotopic ratio measurements by ICP-QMS, such as peak centre correction, detector dead time, mass bias, abundance sensitivity and hydrides formation, instrumental background, and memory blank were carefully evaluated and corrected. Uncertainties of the isotopic ratios, taking into account internal precision of isotope ratio measurements, peak tailing, and hydrides formations ranged from 0.3% to 1.3%. This uncertainties range is quite acceptable for the nuclear data to be used in transmutation studies.

  7. Radiological Characterization Technical Report on Californium-252 Sealed Source Transuranic Debris Waste for the Off-Site Source Recovery Project at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, Alexander [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-04-24

    This document describes the development and approach for the radiological characterization of Cf-252 sealed sources for shipment to the Waste Isolation Pilot Plant. The report combines information on the nuclear material content of each individual source (mass or activity and date of manufacture) with information and data on the radionuclide distributions within the originating nuclear material. This approach allows for complete and accurate characterization of the waste container without the need to take additional measurements. The radionuclide uncertainties, developed from acceptable knowledge (AK) information regarding the source material, are applied to the summed activities in the drum. The AK information used in the characterization of Cf-252 sealed sources has been qualified by the peer review process, which has been reviewed and accepted by the Environmental Protection Agency.

  8. 小儿脑性瘫痪242例临床分析%Clinical analysis of 242 cases of children cerebral palsy

    Institute of Scientific and Technical Information of China (English)

    赵蒙

    2003-01-01

    BACKGROUND:Children cerebral palsy not only affects the quality of the affected children's lives but also burdens the family and the society heavily.Therefore, analysis of the disease and its causes from the viewpoint of clinic might helpful in treatment and prevention of the disease.

  9. 有机磷杀虫药中毒242例临床分析%Clinical study on 242 cases of organophosphorous pesticide poisoning

    Institute of Scientific and Technical Information of China (English)

    汪元平; 李栋

    2001-01-01

    @@ 有机磷杀虫药(organophosphorous insecticides)中毒是基层医院的常见危重症之一,大多采取对症治疗,即根据患者出现的临床症状作出相应的治疗,但由于有机磷杀虫药中毒的患者经常出现一种或多种并发症,这使得治疗的重点不仅要放在对症治疗上,在可能的情况下还要借助各种生化指标早期识别和判断并发症,特别是对于严重并发症的识别尤为重要.

  10. 242-16H 2H EVAPORATOR POT SAMPLING FINAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Krementz, D; William Cheng, W

    2008-06-11

    Due to the materials that are processed through 2H Evaporator, scale is constantly being deposited on the surfaces of the evaporator pot. In order to meet the requirements of the Nuclear Criticality Safety Analysis/Evaluation (NCSA/NCSE) for 2H Evaporator, inspections of the pot are performed to determine the extent of scaling. Once the volume of scale reaches a certain threshold, the pot must be chemically cleaned to remove the scale. Prior to cleaning the pot, samples of the scale are obtained to determine the concentration of uranium and plutonium and also to provide information to assist with pot cleaning. Savannah River National Laboratory (SRNL) was requested by Liquid Waste Organization (LWO) Engineering to obtain these samples from two locations within the evaporator. Past experience has proven the difficulty of successfully obtaining solids samples from the 2H Evaporator pot. To mitigate this risk, a total of four samplers were designed and fabricated to ensure that two samples could be obtained. Samples had previously been obtained from the cone surface directly below the vertical access riser using a custom scraping tool. This tool was fabricated and deployed successfully. A second scraper was designed to obtain sample from the nearby vertical thermowell and a third scraper was designed to obtain sample from the vertical pot wall. The newly developed scrapers both employed a pneumatically actuated elbow. The scrapers were designed to be easily attached/removed from the elbow assembly. These tools were fabricated and deployed successfully. A fourth tool was designed to obtain sample from the opposite side of the pot under the tube bundle. This tool was fabricated and tested, but the additional modifications required to make the tool field-ready could not be complete in time to meet the aggressive deployment schedule. Two samples were obtained near the pot entry location, one from the pot wall and the other from the evaporator feed pipe. Since a third sampler was available and all of the radiological controls were in place, the decision was made to obtain a third sample. The third sampler dropped directly below the riser to obtain a scrape sample from the evaporator cone. Samples were obtained from all of these locations in sufficient quantities to perform the required analysis.

  11. High level waste storage tanks 242-A evaporator standards/requirement identification document

    Energy Technology Data Exchange (ETDEWEB)

    Biebesheimer, E.

    1996-01-01

    This document, the Standards/Requirements Identification Document (S/RIDS) for the subject facility, represents the necessary and sufficient requirements to provide an adequate level of protection of the worker, public health and safety, and the environment. It lists those source documents from which requirements were extracted, and those requirements documents considered, but from which no requirements where taken. Documents considered as source documents included State and Federal Regulations, DOE Orders, and DOE Standards

  12. Comparative Analysis of the Orphan CRISPR2 Locus in 242 Enterococcus faecalis Strains.

    Directory of Open Access Journals (Sweden)

    Karthik Hullahalli

    Full Text Available Clustered, Regularly Interspaced Short Palindromic Repeats and their associated Cas proteins (CRISPR-Cas provide prokaryotes with a mechanism for defense against mobile genetic elements (MGEs. A CRISPR locus is a molecular memory of MGE encounters. It contains an array of short sequences, called spacers, that generally have sequence identity to MGEs. Three different CRISPR loci have been identified among strains of the opportunistic pathogen Enterococcus faecalis. CRISPR1 and CRISPR3 are associated with the cas genes necessary for blocking MGEs, but these loci are present in only a subset of E. faecalis strains. The orphan CRISPR2 lacks cas genes and is ubiquitous in E. faecalis, although its spacer content varies from strain to strain. Because CRISPR2 is a variable locus occurring in all E. faecalis, comparative analysis of CRISPR2 sequences may provide information about the clonality of E. faecalis strains. We examined CRISPR2 sequences from 228 E. faecalis genomes in relationship to subspecies phylogenetic lineages (sequence types; STs determined by multilocus sequence typing (MLST, and to a genome phylogeny generated for a representative 71 genomes. We found that specific CRISPR2 sequences are associated with specific STs and with specific branches on the genome tree. To explore possible applications of CRISPR2 analysis, we evaluated 14 E. faecalis bloodstream isolates using CRISPR2 analysis and MLST. CRISPR2 analysis identified two groups of clonal strains among the 14 isolates, an assessment that was confirmed by MLST. CRISPR2 analysis was also used to accurately predict the ST of a subset of isolates. We conclude that CRISPR2 analysis, while not a replacement for MLST, is an inexpensive method to assess clonality among E. faecalis isolates, and can be used in conjunction with MLST to identify recombination events occurring between STs.

  13. 17 CFR 242.200 - Definition of “short sale” and marking requirements.

    Science.gov (United States)

    2010-04-01

    ... COMMISSION (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY...) introductory text and adding paragraph (g)(2), effective May 10, 2010. For the convenience of the user,...

  14. MeteoIO 2.4.2: a preprocessing library for meteorological data

    Directory of Open Access Journals (Sweden)

    M. Bavay

    2014-12-01

    Full Text Available Using numerical models which require large meteorological data sets is sometimes difficult and problems can often be traced back to the Input/Output functionality. Complex models are usually developed by the environmental sciences community with a focus on the core modelling issues. As a consequence, the I/O routines that are costly to properly implement are often error-prone, lacking flexibility and robustness. With the increasing use of such models in operational applications, this situation ceases to be simply uncomfortable and becomes a major issue. The MeteoIO library has been designed for the specific needs of numerical models that require meteorological data. The whole task of data preprocessing has been delegated to this library, namely retrieving, filtering and resampling the data if necessary as well as providing spatial interpolations and parameterizations. The focus has been to design an Application Programming Interface (API that (i provides a uniform interface to meteorological data in the models, (ii hides the complexity of the processing taking place, and (iii guarantees a robust behaviour in the case of format errors, erroneous or missing data. Moreover, in an operational context, this error handling should avoid unnecessary interruptions in the simulation process. A strong emphasis has been put on simplicity and modularity in order to make it extremely easy to support new data formats or protocols and to allow contributors with diverse backgrounds to participate. This library is also regularly evaluated for computing performance and further optimized where necessary. Finally, it is released under an Open Source license and is available at http://models.slf.ch/p/meteoio. This paper gives an overview of the MeteoIO library from the point of view of conceptual design, architecture, features and computational performance. A scientific evaluation of the produced results is not given here since the scientific algorithms that are used have already been published elsewhere.

  15. MeteoIO 2.4.2: a preprocessing library for meteorological data

    Directory of Open Access Journals (Sweden)

    M. Bavay

    2014-06-01

    (i provides a uniform interface to meteorological data in the models; (ii hides the complexity of the processing taking place; and (iii guarantees a robust behaviour in case of format errors, erroneous or missing data. Moreover, in an operational context, this error handling should avoid unnecessary interruptions in the simulation process. A strong emphasis has been put on simplicity and modularity in order to make it extremely easy to support new data formats or protocols and to allow contributors with diverse backgrounds to participate. This library can also be used in the context of High Performance Computing in a parallel environment. Finally, it is released under an Open Source license and is available at http://models.slf.ch/p/meteoio. This paper gives an overview of the MeteoIO library from the point of view of conceptual design, architecture, features and computational performance. A scientific evaluation of the produced results is not given here since the scientific algorithms that are used have already been published elsewhere.

  16. Tris{2-[4-(2-pyridylpyrimidin-2-ylsulfanyl]ethyl}amine

    Directory of Open Access Journals (Sweden)

    Jian-Quan Wang

    2009-08-01

    Full Text Available The tripodal character of the title compound, C33H30N10S3, arises from the three thioether arms surrounding a central amine N atom. The three arms have approximately the same conformation but distinct geometries in a trans–trans–cis conformation, resulting in a short pyridine–sulfanyl N...S distance of 4.320 (7 Å. The distances of the central N atom to the N atoms of three pyridine rings in the arms are 8.305 (7, 8.032 (7 and 5.076 (9Å. In the crystal, molecules are joined into a three-dimensional supramolecular network via effective π–π stacking between adjacent heterocycles [centroid–centroid distances of 3.700 (3–4.118 (4 Å between adjacent interlayer pyrimidine rings and 3.676 (4 Å between the pyridine rings].

  17. 36 CFR 242.25 - Subsistence taking of fish, wildlife, and shellfish: general regulations.

    Science.gov (United States)

    2010-07-01

    ... not include permanent hotels or roadhouses on the State road system or at State or Federally... processed for human consumption in a manner which saves or prevents the edible meat from waste, and... may not use wildlife as food for a dog or furbearer, or as bait, except as allowed for in §...

  18. Disaster Preparedness Utilization Field/Disaster Preparedness Career Ladder, AFSCs 05XX/242X0

    Science.gov (United States)

    1988-11-01

    STG219, N=12) PERCENT MEMBERS TASKS PERFORMING E285 TYPE CORRESPONDENCE, SUCH AS REPORTS OR RECORDS 100 E252 MAINTAIN DISASTER PREPAREDNESS (DP...TECHNICAL ORDER FILES 67 E252 MAINTAIN DISASTER PREPAREDNESS (DP) OFFICE ADMINISTRATIVE FILES 56 A9 TABLE AlO REPRESENTATIVE TASKS PLRFORMED BY CONTROL

  19. 17 CFR 242.609 - Registration of securities information processors: form of application and amendments.

    Science.gov (United States)

    2010-04-01

    ... Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Regulation Nms-Regulation of the National Market System §...

  20. High level waste storage tanks 242-A evaporator S/RID phase II assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Biebesheimer, E.

    1996-09-27

    This document, the Standards/Requirements Identification Document (S/RID) Phase 2 Assessment Report for the subject facility, represents the results of a Performance Assessment to determine whether procedures containing S/RID requirements are fully implemented by field personnel in the field. It contains a summary report and three attachments; an assessment schedule, performance objectives, and assessments for selected functional areas.

  1. New measurement of the 242Pu(n,γ) cross section at n_TOF

    OpenAIRE

    Lerendegui-Marco J.; Guerrero C.; Cortés-Giraldo M. A.; Quesada J.M.; Mendoza E.; Cano-Ott D.; Eberhardt K.; Junghans A.

    2016-01-01

    WONDER-2015 – 4th International Workshop On Nuclear Data Evaluation for Reactor applications The use of MOX fuel (mixed-oxide fuel made of UO2 and PuO2) in nuclear reactors allows substituting a large fraction of the enriched Uranium by Plutonium reprocessed from spent fuel. With the use of such new fuel composition rich in Pu, a better knowledge of the capture and fission cross sections of the Pu isotopes becomes very important. In particular, a new series of cross section evaluations hav...

  2. 2-[4-(2-Chloroacetylphenyl]-2-methyl-1-(pyrrolidin-1-ylpropan-1-one

    Directory of Open Access Journals (Sweden)

    Dong-mei Ren

    2013-08-01

    Full Text Available The asymmetric unit of the title compound, C16H20ClNO2, contains two molecules in which the dihedral angles between the benzene ring and the plane of the amide unit are 77.4 (1 and 81.1 (1°. In both molecules, the five-membered ring adopts an envelope conformation with one of the β-C atoms as the flap. In the crystal, molecules are connected via C—H...O hydrogen bonds, forming chains along the b-axis direction. These chains are further linked by C—H...π interactions, forming a three-dimensional network.

  3. 36 CFR 242.16 - Customary and traditional use determination process.

    Science.gov (United States)

    2010-07-01

    ... determinations based on application of the following factors: (1) A long-term consistent pattern of use... characterized by efficiency and economy of effort and cost, conditioned by local characteristics; (4) The... which includes the handing down of knowledge of fishing and hunting skills, values, and lore...

  4. NATO/CCMS PILOT STUDY - CLEAN PRODUCTS AND PROCESSES (PHASE I) 2000 ANNUAL REPORT, NUMBER 242

    Science.gov (United States)

    This annual report presents the proceedings of the Third Annual NATO/CCMS pilot study meeting in Copenhagen, Denmark. Guest speakers focused on efforts in the area of research of clean products and processes, life cycle analysis, computer tools and pollution prevention.

  5. 18 CFR 367.2420 - Account 242, Miscellaneous current and accrued liabilities.

    Science.gov (United States)

    2010-04-01

    ..., FEDERAL POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Current and Accrued Liabilities... Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC...

  6. High-level waste storage tank farms/242-A evaporator standards/requirements identification document (S/RID), Vol. 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The purpose of this Requirements Identification Document (RID) section is to identify, in one location, all of the facility specific requirements and good industry practices which are necessary or important to establish an effective Issues Management Program for the Tank Farm Facility. The Management Systems Functional Area includes the site management commitment to environmental safety and health (ES&H) policies and controls, to compliance management, to development and management of policy and procedures, to occurrence reporting and corrective actions, resource and issue management, and to the self-assessment process.

  7. Bradley Fighting Vehicle Gunnery: An Analysis of Engagement Strategies for the M242 25-mm Automatic Gun

    Science.gov (United States)

    1993-03-01

    weapons elevation by means of a servo driven mirror that is electrically linked to the selected weapon’s rotor movement. ... In gun mode, the mirror...follows the gun rotor elevation/depression. 25-mm boresight adjustments in elevation movea the mirror to align with the 25-mm. Azimuth adjustment moves the...to model in that it requires a %ange-in proceso Lco effectively 5ngige most targets. While this is not unique, given a similar requirement for most

  8. Pico BTS 242:西门子室内和热点地区的解决方案

    Institute of Scientific and Technical Information of China (English)

    邓学军

    2002-01-01

    @@ 1引言 移动网络运营商的网络质量是赢得并保留客户,从而使收益获得稳定增长的基础.在衡量移动网络质量的众多指标中,网络的覆盖及覆盖范围内的信号质量是两个非常重要的方面.目前,国内GSM运营商的网络在历经多年的充分发展后,已基本解决了覆盖问题,从城市、郊区到农村,基本上有话务量需求的地区都已得到了覆盖.

  9. High-level waste storage tank farms/242-A evaporator standards/requirements identification document (S/RID), Vol. 3

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Safeguards and Security (S&S) Functional Area address the programmatic and technical requirements, controls, and standards which assure compliance with applicable S&S laws and regulations. Numerous S&S responsibilities are performed on behalf of the Tank Farm Facility by site level organizations. Certain other responsibilities are shared, and the remainder are the sole responsibility of the Tank Farm Facility. This Requirements Identification Document describes a complete functional Safeguards and Security Program that is presumed to be the responsibility of the Tank Farm Facility. The following list identifies the programmatic elements in the S&S Functional Area: Program Management, Protection Program Scope and Evaluation, Personnel Security, Physical Security Systems, Protection Program Operations, Material Control and Accountability, Information Security, and Key Program Interfaces.

  10. High-level waste storage tank farms/242-A evaporator standards/requirements identification document (S/RID), Vol. 7

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    This Requirements Identification Document (RID) describes an Occupational Health and Safety Program as defined through the Relevant DOE Orders, regulations, industry codes/standards, industry guidance documents and, as appropriate, good industry practice. The definition of an Occupational Health and Safety Program as specified by this document is intended to address Defense Nuclear Facilities Safety Board Recommendations 90-2 and 91-1, which call for the strengthening of DOE complex activities through the identification and application of relevant standards which supplement or exceed requirements mandated by DOE Orders. This RID applies to the activities, personnel, structures, systems, components, and programs involved in maintaining the facility and executing the mission of the High-Level Waste Storage Tank Farms.

  11. 32 CFR 242.8 - Academic, intellectual, and personal requirements for admission to the first-year class.

    Science.gov (United States)

    2010-07-01

    ... academic requirements that are requisite for admission. These are as follows: (i) College preparation. All... matriculation. (ii) Prerequisite course work. Area of specialization in college is not a limiting factor in... a requirement for all entering students. The minimum undergraduate science prerequisites...

  12. 0.94 - 2.42 micron ground-based transmission spectra of the hot-Jupiter HD-189733b

    CERN Document Server

    Danielski, C; Waldmann, I P; Hollis, M D J; Tinetti, G; Swain, M R

    2012-01-01

    We present here new transmission spectra of the hot Jupiter HD-189733b using the SpeX instrument on the NASA Infrared Telescope Facility. We obtained two nights of observations where we recorded the primary transit of the planet in the J-, H- and K-bands simultaneously, covering a total spectral range from 0.94 to 2.4 micron. We used Fourier analysis and other de-trending techniques validated previously on other datasets to clean the data. We tested the statistical significance of our results by calculating the auto-correlation function, and we found that, after the detrending, white noise dominates at most frequencies. Additionally, we repeated our analysis on the out-of-transit data only, showing that the residual telluric contamination is well within the error bars. While these techniques are very efficient when multiple nights of observations are combined together, our results prove that even one good night of observations is enough to provide statistically meaningful data, which might appear counterintui...

  13. Giraut de Borneil, “Ben cove, pus ja bayssa·l ram” (BdT 242.25

    Directory of Open Access Journals (Sweden)

    Pietro G. Beltrami

    2009-01-01

    Full Text Available This paper will offer a revision, with a translation and commentary, of the text of “Ben cove, pus ja baissa·l ram” by Giraut de Borneil, with a new examination of the manuscript tradition after the monographic editions by Adolf Kolsen and Ruth Verity Sharman. In particular the paper will offer a new reading of l. 20, transmitted only by Chansonnier a, while the other manuscripts have a lacuna that seems to have been crudely corrected by Sg. The interpretation of “e leis s’embla, que a miralh” as ‘and she, who holds a mirror, is elusive’ restores an image of the lady filled with pride on seeing her own beauty reflected in a mirror that is also in Raimbaut d’Aurenga and Pons de Capduoill. In the Introduction the text is interpreted as an example of two different aspects of Giraut’s poetry, expressed through two different voices in the text, the author’s ‘self’ and the lover’s ‘self’. The former, who speaks in the first stanza, gives importance to his aiming for excellence; the latter, who speaks in the following stanzas, presents contents and forms belonging to a discourse on love. Finally, the point is made that where the two parts meet, at l. 9 “E per ma guerreira cui am” ‘and for my enemy whom I love’, the text is of great poetic intensity.

  14. SU-E-T-242: Design of a Novel Afterloader Clearance QA Device for Biliary HDR Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Mullins, JP; Deufel, CL [Mayo Clinic, Rochester, MN (United States)

    2015-06-15

    Purpose: Bile duct cancer affects 2–3 thousand people annually in the United States. Radiation therapy has been shown to double median survival, with combined external beam and intraluminal high dose-rate (HDR) brachytherapy being most effective. Endoscopic retrograde cholangiopancreatography (ERCP) biliary HDR, a less-invasive alternative to trans-hepatic brachytherapy, is delivered through a catheter that travels a tortuous path from nose to bile duct, requiring wire drive force and dexterity beyond typical afterloader performance specifications. Thus, specific afterloader quality assurance(QA) is recommended for this procedure. Our aim was to create a device and process for Varisource afterloader clearance QA with objectives that it be quantitative and can monitor afterloader performance over time, compare performance between two distinct afterloaders and potentially Result in a predictive nomogram for patient-specific clearance. Methods: Based on retrospective reconstruction of 20 ERCP patient anatomies, we designed a phantom to test afterloader ability to drive the source wire along an intended treatment path. The ability of the afterloader to fully extend the intended treatment path is a function of number and diameters of turns. We have determined experimentally that relative position of the turns does not impact performance. Results: Both patient and QA paths involve three common turns/loops: a large turn representing the stomach(10.8cm±2.0cm), an elliptical loop representing the duodenum(7.3cm±1.5cmx4.8cm±0.7cm), and a final turn at the end of the bile duct that may be tight for some patient-specific anatomies and absent in others(3.7cm±0.7cm, where present). Our phantom design uses anatomical average turn diameters for the stomach and duodenum then terminates in a turn of quantitatively selectable diameter. The smallest final turn diameter that an afterloader can pass is recorded as the QA parameter. Conclusion: With this device and QA process, we have the ability to quantitatively evaluate and track our afterloader performance for a technically challenging ERCP brachytherapy procedure.

  15. Bensaâd Ali (dir., L’eau et ses enjeux au Sahara, Iremam, Karthala, 2011, 242 p.

    Directory of Open Access Journals (Sweden)

    Jean-Louis Marçot

    2011-11-01

    Full Text Available Je dirai en premier ma déception. Comme le suggère Ali Bensaâd à l’entrée du livre qu’il a dirigé, l’enjeu de l’eau au Sahara n’est ni plus ni moins que la conservation de la vie dans ce milieu qui lui est particulièrement hostile - la vie sous tous ses aspects. Or cet enjeu « vital » a été négligé au profit d’une approche micro-géographique. C’est pourtant par cette entrée que le travail collectif aurait pu légitimement intéresser un vaste public. Comment l’eau existe-t-elle à l’état naturel...

  16. High level waste storage tank farms/242-A evaporator standards/requirements identification document phase 1 assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Biebesheimer, E., Westinghouse Hanford Co.

    1996-09-30

    This document, the Standards/Requirements Identification Document (S/RID) Phase I Assessment Report for the subject facility, represents the results of an Administrative Assessment to determine whether S/RID requirements are fully addressed by existing policies, plans or procedures. It contains; compliance status, remedial actions, and an implementing manuals report linking S/RID elements to requirement source to implementing manual and section.

  17. 32 CFR 242a.4 - Grounds on which meetings may be closed, or information may be withheld.

    Science.gov (United States)

    2010-07-01

    ... information would: (1) Interfere with enforcement proceedings; (2) Deprive a person of a right to a fair trial...) Disclose the identity of a confidential source and, in the case of a record compiled by a criminal law enforcement authority in the course of a criminal investigation, or by an agency conducting a lawful...

  18. 47 CFR 15.242 - Operation in the bands 174-216 MHz and 470-668 MHz.

    Science.gov (United States)

    2010-10-01

    ... bands 174-216 MHz and 470-668 MHz. (a) The marketing and operation of intentional radiators under the... implementation of the digital television services. The operating frequencies of the part 15 devices may need...

  19. 78 FR 21567 - Installation of Radiation Alarms for Rooms Housing Neutron Sources

    Science.gov (United States)

    2013-04-11

    ... californium-252 (Cf-252). A licensee's decision to use a specific type of source may depend upon cost, availability, and the dependence upon historical data with which to compare current measurement results. The...

  20. Takotsubo cardiomyopathy associated with sepsis due to Pseudomonas aeruginosa pneumoniadoi: 10.12662/2317-3076jhbs.v3i4.169.p242-244.2015

    Directory of Open Access Journals (Sweden)

    Márcio da Silva Pereira

    2015-12-01

    Full Text Available The authors describe a case report of a 71 year-old female patient admitted at the emergency service due to severe precordial chest pain associated with dyspnea and sweating. The electrocardiogram performed on admission showed ST elevation on V2 and V3 leads and the ventriculography revealed left ventricular apical ballooning, denoting the diagnosis of Takotsubo Cardiomyopathy. At the eighth day of hospitalization, although the heart function was recovered, the patient died due the clinical complications of a septic shock.

  1. Final characterization and safety screen report of double shell tank 241-AP-104 for 242-A evaporator, campaign 96-1

    Energy Technology Data Exchange (ETDEWEB)

    Miller, G.L.

    1996-04-19

    This data package satisfies the requirement for a format IV, final report. It is a follow-up to the 45-day safety screen report for tank AP-104. Evaporator candidate feed from tank 241-AP-104 (hereafter referred to as AP-104) was characterized for physical, inorganic, organic and radiochemical parameters by the Westinghouse Hanford Company, 222-S Laboratory, and by the Battelle Pacific Northwest National Laboratory (PNNL), Analytical Chemistry Laboratory (ACL) as directed by the Tank Sample and Analysis Plan (TSAP), References 1 through 4. Preliminary data in the form of summary analytical tables were provided to the project in advance of this final report to enable early estimation of evaporator operational parameters, using the Predict modeling program. Laboratory analyses at ACL Laboratory was performed according to the TSAP. Analyses were performed at the 222-S Laboratory as defined and specified in the TSAP and the Laboratory`s Quality Assurance Plan, References 5 and 6. Any deviations from the instructions documented in the TSAP are discussed in this narrative and are supported with additional documentation. SAMPLING The TSAP, section 2, provided sampling information for waste samples collected from tank AP-104. The bottle-on-a-string method was used to collect liquid grab samples from the tank. Each glass sample bottle was amber, precleaned, and contained approximately 100 milliliters. Each bottle was closed with a teflon seal cap (or teflon septum for volatile organic analysis samples). Field blank samples were prepared by placing deionized water into sampling bottles, lowering the unclosed bottles into the riser for a period of time, retrieving them from the riser, and then closing the bottles with the same types of caps used for the tank samples. None of the samples were preserved by acidification. Upon receipt, the sample bottles destined for organic analyses were placed in a refrigerator. No attempt was made during sampling to assure the complete filling of the bottles so as to exclude all headspace. These actions were consistent with safety procedures, which attempt to limit personnel exposure to hazardous ionizing radiation.

  2. Earth system modelling on system-level heterogeneous architectures: EMAC (version 2.42) on the Dynamical Exascale Entry Platform (DEEP)

    Science.gov (United States)

    Christou, Michalis; Christoudias, Theodoros; Morillo, Julián; Alvarez, Damian; Merx, Hendrik

    2016-09-01

    We examine an alternative approach to heterogeneous cluster-computing in the many-core era for Earth system models, using the European Centre for Medium-Range Weather Forecasts Hamburg (ECHAM)/Modular Earth Submodel System (MESSy) Atmospheric Chemistry (EMAC) model as a pilot application on the Dynamical Exascale Entry Platform (DEEP). A set of autonomous coprocessors interconnected together, called Booster, complements a conventional HPC Cluster and increases its computing performance, offering extra flexibility to expose multiple levels of parallelism and achieve better scalability. The EMAC model atmospheric chemistry code (Module Efficiently Calculating the Chemistry of the Atmosphere (MECCA)) was taskified with an offload mechanism implemented using OmpSs directives. The model was ported to the MareNostrum 3 supercomputer to allow testing with Intel Xeon Phi accelerators on a production-size machine. The changes proposed in this paper are expected to contribute to the eventual adoption of Cluster-Booster division and Many Integrated Core (MIC) accelerated architectures in presently available implementations of Earth system models, towards exploiting the potential of a fully Exascale-capable platform.

  3. Giraut de Borneil, “Quan lo fregz e·l glatz e la neus” (BdT 242.60

    Directory of Open Access Journals (Sweden)

    Pietro G. Beltrami

    2011-12-01

    Full Text Available This paper provides a critical edition, with a new hypothesis concerning two difficult loci, of “Quan lo fregz e·l glatz e la neus”, one of the most significant love songs by Giraut de Borneil. For l. 48 (according to the order of the stanzas in Kolsen’s edition which is confirmed here, I will argue that “gers”, present in nearly all the manuscripts and editions, but never explained satisfactorily and unique from the lexical viewpoint, is a ghost word. Thus I will suggest accepting the lesson of ms. B as a suitable, ancient conjecture: ‘of those who are inside (the beseiged castle and forced to surrender’ que an grans guerriers, ‘who have great enemies’. For l. 58 none of the solutions put forward so far are convincing, thus I will tentatively propose a new conjecture: the lover fears that his life will become plus breus... “que del quint dels quars”, ‘shorter that the fifth of the quarter (of the day’, that is, it will be cut off. This restores a rhetorical figure of repetition that marks the end of each stanza after the second and which has been lost in nearly all the manuscripts and editions. My reading of the text will underline its distinctive aspects: a large number of quite difficult similes, emphasis on the figure of the lover, a lack of the author intervention and of the sententiae and forms of argument that characterise this poet, a fast pace created by the syntactic and rhetorical structure. I will also examine all that may serve to place the text within a particular historical context, although despite the many hypotheses, the only sure element is that it was written for a courtly occasion in the presence of Richard the Lionheart.

  4. SU-E-T-242: Monte Carlo Simulations Used to Test the Perturbation of a Reference Ion Chamber Prototype Used for Small Fields

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez Quino, L; Calvo, O; Huerta, C; DeWeese, M [Midsouth Radation Physics, Little Rock, AR (United States)

    2014-06-01

    Purpose: To study the perturbation due to the use of a novel Reference Ion Chamber designed to measure small field dosimetry (KermaX Plus C by IBA). Methods: Using the Phase-space files for TrueBeam photon beams available by Varian in IAEA-compliant format for 6 and 15 MV. Monte Carlo simulations were performed using BEAMnrc and DOSXYZnrc to investigate the perturbation introduced by a reference chamber into the PDDs and profiles measured in water tank. Field sizes ranging from 1×1, 2×2,3×3, 5×5 cm2 were simulated for both energies with and without a 0.5 mm foil of Aluminum which is equivalent to the attenuation equivalent of the reference chamber specifications in a water phantom of 30×30×30 cm3 and a pixel resolution of 2 mm. The PDDs, profiles, and gamma analysis of the simulations were performed as well as a energy spectrum analysis of the phase-space files generated during the simulation. Results: Examination of the energy spectrum analysis performed shown a very small increment of the energy spectrum at the build-up region but no difference is appreciated after dmax. The PDD, profiles and gamma analysis had shown a very good agreement among the simulations with and without the Al foil, with a gamma analysis with a criterion of 2% and 2mm resulting in 99.9% of the points passing this criterion. Conclusion: This work indicates the potential benefits of using the KermaX Plus C as reference chamber in the measurement of PDD and Profiles for small fields since the perturbation due to in the presence of the chamber the perturbation is minimal and the chamber can be considered transparent to the photon beam.

  5. (001–002) Proposals to amend Art. 32.2, 23.5, and 24.2 to clarify the treatment of transcribed Greek terminations of epithets

    Science.gov (United States)

    The International Code of Nomenclature for algae, fungi and plants is revised every six years to incorporate decisions of the Nomenclature Section of successive International Botanical Congresses (IBC) on proposals to amend the Code. The proposals in this paper will be considered at the IBC in Shenz...

  6. Guillermo Banzato (Dir. 2013. Tierras Rurales. Políticas, transacciones y mercados en Argentina, 1780-1914. Rosario. Prohistoria Ediciones. 242 p.

    Directory of Open Access Journals (Sweden)

    Diego Muñiz

    2014-04-01

    Full Text Available La reseña del presente libro brinda un panorama de lo acontecido con los mercados de tierras en diferentes provincias -Buenos Aires, Entre Ríos, Córdoba, Santa Fe, Jujuy, Santiago del Estero y Mendoza- entre los años 1780 y 1914. La investigación realizada por los autores permite observar variables que condicionaron el desarrollo diferenciado de los mercados en las provincias estudiadas. Entre ellas, las posibilidades y estrategias de expansión y consolidación territorial llevadas adelante por los gobiernos provinciales, el proceso de enajenación de tierras públicas (que perseguía diferentes objetivos, entre los cuales se destaca la urgencia de recursos económicos, y el modo en que este accionar del Estado afectó las transacciones entre privados.

  7. Wide Band Gap Semiconductors Symposium Held in Boston, Massachusetts on 2-6 December 1991. Materials Research Society Symposium Proceedings. Volume 242

    Science.gov (United States)

    1992-01-01

    Diego. CA, April 23. 1991. 11. Yukio Saito, Kouji Sato. Hideaki Tanaka, Kazunori Fujita. Shinpei Matuda, J. Mater. Sci. 23. 842 (1988). 12. Yukio Saito...DEAC04-76DP00789. REFERENCES I. Jeffrey T. Cheung and Haluk Sankur, CRC Crit. Rev. in Solid State and Mat. Sci. 15, 6 (1988). 2. 0. Mishima in...Yokoyama, Takeshi lmura and Yukio Osaka, Jap. J. App. Phys. 2.6, L1435 (1987). 5. S. Y. Shapoval, V.T. Petrashov, 0. A. Popov, A. 0. Westner, M. D

  8. Thermodynamic Assessment of Hot Corrosion Mechanisms of Superalloys Hastelloy N and Haynes 242 in Eutectic Mixture of Molten Salts KF and ZrF4

    Energy Technology Data Exchange (ETDEWEB)

    Michael V. Glazoff

    2012-02-01

    The KF - ZrF4 system was considered for the application as a heat exchange agent in molten salt nuclear reactors (MSRs) beginning with the work carried out at ORNL in early fifties. Based on a combination of excellent properties such as thermal conductivity, viscosity in the molten state, and other thermo-physical and rheological properties, it was selected as one of possible candidates for the nuclear reactor secondary heat exchanger loop.

  9. catena-Poly[[[tetraaquacobalt(II]-μ-4,4′-bipyridine-κ2N:N′] 2-[4-(2-carboxylatoethylphenoxy]acetate

    Directory of Open Access Journals (Sweden)

    Xi-Fang Wang

    2009-07-01

    Full Text Available In the title complex, {[Co(C10H8N2(H2O4](C11H10O5}n, the unique CoII ion lies on an inversion center and is coordinated by two N atoms from two 4,4′-bipyridine ligands and four O atoms from four water molecules in a slightly distorted octahedral coordination geometry. The 4,4′-bipyridine ligands bridge CoII ions into a one-dimensional chain structure. In the crystal structure, intermolecular O—H...O hydrogen bonds link cations and anions into a three-dimensional network. The dianions are completely disordered about an inversion center.

  10. On extrapolation blowups in the 242X-2006-74960-i1.gif"/> scale

    OpenAIRE

    2006-01-01

    Yano's extrapolation theorem dated back to 1951 establishes boundedness properties of a subadditive operator acting continuously in for close to and/or taking into as and/or with norms blowing up at speed and/or , . Here we give answers in terms of Zygmund, Lorentz-Zygmund and small Lebesgue spaces to what happens if as . The study has been motivated by current investigations of convolution maximal functions in stochastic analysis, where the problem occurs for . We also touch the ...

  11. SYNTHESIS, COMPUTATIONAL STUDY AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF 2-[4-(2-CHLOROBENZYL/BENZOYL SUBSTITUTED PIPERAZIN-1-YL]-N-PHENYLACETAMIDE: POTENTIAL ANTIPSYCHOTICS

    Directory of Open Access Journals (Sweden)

    Tomar Amita

    2011-06-01

    Full Text Available Benzyl and benzoyl substituted acetamides have been synthesized and evaluated as potential antipsychotic agents. The target compounds (4a-b were prepared by reaction of substituted anilines with chloroacetylchloride which further treated with 2-chlorobenzyl or 2-chlorobenzoyl piperazine in presence of potassium carbonate and potassium iodide as catalyst in acetonitrile. The structures of the target compounds (4a-b were characterized on the basis of their M.P., TLC, IR and 1H-NMR data. Computational studies of target compounds (4a-b were carried out by using software programs. The target compounds showed good similarity with respect to standard drugs. The target compounds (4a-b showed inhibition of 5-HTP induced head twitches behavior and low induction of catalepsy in mice.

  12. mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma

    Science.gov (United States)

    Benavides-Serrato, Angelica; Anderson, Lauren; Holmes, Brent; Cloninger, Cheri; Artinian, Nicholas; Bashir, Tariq; Gera, Joseph

    2014-01-01

    Dual-specificity phosphatases (DUSPs) dephosphorylate MAP kinases (MAPKs) resulting in their inactivation. Activation of MAPK signaling leads to enhanced DUSP expression, thus establishing feedback regulation of the MAPK pathway. The DUSPs are subject to regulation at the post-translational level via phosphorylation resulting in alterations of protein stability. Here we report that mTORC2 function leads to stabilization of the p38 MAPK phosphatase, DUSP10, thereby inhibiting p38 activity. We demonstrate that mTORC2 binds DUSP10 and phosphorylates DUSP10 on serine residues 224 and 230. These phosphorylation events block DUSP10 turnover resulting in inactivation of p38 signaling. We further show that insulin-stimulated PI3K/mTORC2 signaling regulates DUSP10 stability and p38 activity. Importantly, knockdown of DUSP10 or ectopic overexpression of nonphosphorylatable or phosphomimetic DUSP10 mutants was sufficient to confer differential mTOR kinase inhibitor responses to GBM cells in vitro and in murine xenografts. Finally, DUSP10 was shown to be overexpressed in a significant number of GBM patients. These data demonstrate the ability of the mTORC2 pathway to exert regulatory effects on the DUSP10/p38 feedback loop to control the cellular effects of mTOR kinase inhibitors in GBM and support the use of DUSP10 expression as a surrogate biomarker to predict responsiveness. PMID:25568665

  13. Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

    Directory of Open Access Journals (Sweden)

    Dan E Arking

    2011-06-01

    Full Text Available Sudden cardiac death (SCD continues to be one of the leading causes of mortality worldwide, with an annual incidence estimated at 250,000-300,000 in the United States and with the vast majority occurring in the setting of coronary disease. We performed a genome-wide association meta-analysis in 1,283 SCD cases and >20,000 control individuals of European ancestry from 5 studies, with follow-up genotyping in up to 3,119 SCD cases and 11,146 controls from 11 European ancestry studies, and identify the BAZ2B locus as associated with SCD (P = 1.8×10(-10. The risk allele, while ancestral, has a frequency of ~1.4%, suggesting strong negative selection and increases risk for SCD by 1.92-fold per allele (95% CI 1.57-2.34. We also tested the role of 49 SNPs previously implicated in modulating electrocardiographic traits (QRS, QT, and RR intervals. Consistent with epidemiological studies showing increased risk of SCD with prolonged QRS/QT intervals, the interval-prolonging alleles are in aggregate associated with increased risk for SCD (P = 0.006.

  14. A new shipping container for an intense neutron emitter

    Energy Technology Data Exchange (ETDEWEB)

    Bigelow, J.E.; Alexander, C.W.; Pace, J.V. III; Simmons, C.M.

    1994-06-01

    Californium-252 is an intense neutron emitter (2.34 {times} 10{sup 12} n/s{center_dot}g) used in medicine, research, and industry. The western world`s sole source of this rare radioisotope is the Californium Facility at Oak Ridge National Laboratory`s Radiochemical Engineering Development Center (REDC). A project has been initiated at the REDC to design a new Type B Californium Shipping Container. This effort is essential for future transportation of californium to meet the needs of users all over the world. The shipping container must meet all requirements for transport by motor freight, air, vessel, and rail, both domestic and foreign. There are unique problems in the design, fabrication, and licensing of a new Type B shipping container that will accommodate up to 60 milligrams of californium-252. One of the first challenges in the design phase of the project is the selection of a material to shield the high neutron flux. The more stringent safety precautions of today`s world impel us to consider more exotic materials for such a purpose. The candidate materials must be examined not just for their neutron shielding properties, but also in conjunction with other properties such as thermal and structural requirements to withstand the hypothetical accident conditions. The design and building of such a container is a formidable task requiring much planning. The licensing process, with the complex, interactive federal codes, is a special challenge and may be the biggest on the project in terms of time and money.

  15. A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

    DEFF Research Database (Denmark)

    Leslie, Elizabeth J; Carlson, Jenna C; Shaffer, John R

    2016-01-01

    Orofacial clefts (OFCs), which include non-syndromic cleft lip with or without cleft palate (CL/P), are among the most common birth defects in humans, affecting approximately 1 in 700 newborns. CL/P is phenotypically heterogeneous and has a complex etiology caused by genetic and environmental...

  16. Composição química do capim-Mombaça (Panicum maximum Jacq. cv. Mombaça adubado com diferentes fontes de fósforo sob pastejo - DOI: 10.4025/actascianimsci.v29i1.242 Chemical composition of Mombaça grass (Panicum maximum Jacq. cv. Mombaça fertilized with different phosphorus on grazing - DOI: 10.4025/actascianimsci.v29i1.242

    Directory of Open Access Journals (Sweden)

    Ulysses Cecato

    2007-11-01

    Full Text Available O objetivo foi avaliar a composição química do Panicum maximum Jacq. cv. Mombaça, adubado com 140 kg ha-1 de P2O5 com diferentes fontes de fósforo, sob pastejo, no período de dezembro de 2002 a abril de 2003, com intervalo de coleta a cada 28 dias. Tratamentos: 1- termofosfato magnesiano Yoorin®; 2-fosfato natural Gafsa®; 3-superfosfato simples + superfosfato triplo (SS + ST; e 4-testemunha. Os teores de proteína bruta na lâmina foliar (PBf e colmo (PBc, nitrogênio insolúvel em detergente ácido (NIDA, fibra em detergente neutro (FDN, fibra em detergente ácido (FDA, celulose (CEL, hemicelulose (HCEL, lignina (LIG, extrato etéreo (EE, cálcio (Ca, fósforo (P, cinzas e carboidratos não-estruturais (CNE, não foram influenciados pela adubação fosfatada. As variáveis PBc, FDNf, FDNc, LIGf, LIGc, CELf, CELc, NIDAf, EEf, EEc, Caf, Cac, Pf, Pc, CINZAc, CNEc, apresentaram efeito do período de coleta. Não ocorreu diferença na composição química da forragem do capim-Mombaça em função das fontes de fósforo utilizadas na adubação da pastagem. As variações qualitativas foram de baixa magnitude.This study aimed to evaluate the chemical composition of Panicum maximum Jacq. cv. Mombaça. Grassland was fertilized with 140 kg ha-1 of P2O5 from different phosphorus sources on grazing, in December, 2002, until April, 2003, with a collection interval of every 28 days. Treatments: 1-Yoorin® magnesium thermophosphate; 2-Gafsa® natural phosphate; 3-simple superphosphate + triple superphosphate (SS + TS and 4-control. Leaf (lCP and stem (sCP crude protein, acid detergent fiber nitrogen (ADFN, neutral detergent fiber (NDF, acid detergent fiber (ADF, cellulose (CEL, hemicellulose (HEM, lignin (LIG, ether extract (EE, calcium (Ca, phosphorus (P, ash (A and non-structural carbohydrates (NSC were not influenced by phosphated fertilization. The variables sCP, lNDF, sNDF, sLIG, lLIG, sCEL, lCEL, lADFN, sEE, lEE, lCa, sCa, lP, sP, sA and sNSC, showed some effects from the collection period. There was no difference in the chemical composition of forage of the grass-Mombaça in function of phosphorus sources used in the pasture. The qualitative variations were of low magnitude.

  17. Discovery of Isotopes of the Transuranium Elements with 93 <= Z <= 98

    CERN Document Server

    Fry, C

    2012-01-01

    One hundred and five isotopes of the transuranium elements neptunium, plutonium, americium, curium, berkelium and californium have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  18. 78 FR 8329 - Federal Housing Administration (FHA): Hospital Mortgage Insurance Program-Refinancing Hospital Loans

    Science.gov (United States)

    2013-02-05

    ... understanding how the Section 242 program works. C. Costs and Benefits This rule will not address all financing... balance remaining unused in the fund at final endorsement will be treated in accordance with 24 CFR 242.43.... Comment: Market Need study requirements should be revised. Section 242.16(b)(5) of the proposed...

  19. GETDB: 103550 [GETDB

    Lifescience Database Archive (English)

    Full Text Available onal Institute of Genetics. FM7c Link to clone table - 1 242 Link to cluster table 242 1 Request - cns, mg, good driver...er table 242 Num of clusters 1 Stock Request Request - Embryonic Expression cns, mg, good driver Larval GFP

  20. Measurement of the energy spectra of fission fragments using nuclear track detectors and digital image processing

    Energy Technology Data Exchange (ETDEWEB)

    Espinosa, Guillermo; Golzarri, Jose I. [Instituto de Fisica, Universidad Nacional Autonoma de Mexico, A.P. 20-364, Mexico D.F. 01000 (Mexico); Castano, Victor M., E-mail: castano@fata.unam.m [Centro de Fisica Aplicada y Tecnologia Avanzada, Universidad Nacional Autonoma de Mexico, Boulevard Juriquilla 3001, Santiago de Queretaro, Queretaro 76230 (Mexico)

    2010-08-15

    Energy spectra of fission fragments were determined using a Nuclear Track Methodology (NTM) supported by digital image analysis and numerical data processing using a standard personal computer. The analysis of a californium ({sup 252}Cf) spectrum with this approach shows improvement compared with the values reported previously using the standard procedure, in terms of resolution and accuracy. This new method adds full automation to the technical advantages and cost effectiveness of an NTM.

  1. The Majority of Library Clients Still Use Person-to-Person Interaction When Asking Reference Questions. A review of: De Groote, Sandra L. “Questions Asked at the Virtual and Physical Health Sciences Reference Desk: How Do They Compare and What Do They Tell Us?” Medical Reference Services Quarterly 24.2 (Summer 2005: 11-23.

    Directory of Open Access Journals (Sweden)

    Suzanne Pamela Lewis

    2006-03-01

    Full Text Available Objective - To identify similarities and difference in the questions asked at the virtual and physical refernece desks of a helath scienmces library, in order to better undertand user needs and highlight areas for service improvement. Also to retrospectively analyze reference statistics collected over the previous six years. Design - Use study; retrospective study of reference statistics for the period July 1997 to June 2003; literature review. Setting - Large academic helath sciences library in the United States. Subjects - All questions asked at the reference and information desks, plus questions submitted to the University-wide virtual reference service and answered by a health sciences librarian, over a period of one month. The questions were asked by faculty, staff, students and members of the public. Methods - A literature review was carried out to examine the types of information/reference questions typically asked in health sciences libraries both before and after the mass introduction of remote end-user searching of online resources and the establishment of virtual reference services. Next, the reference statistics collected at the University of Illinois at Chicage (UIC Library of the Health Sciences between July 1997 and June 2003 were examined. For most of this period a digital reference service was offered using a listserv address to which patrons would submit email queries. Beginning in March 2003, a formal virtual reference service (chat and email was provided using commercial software. Finally, data was gathered on questions answered by a health sciences librarians, and clients who asked the question, at either the physical or cirtual reference desk, during the month of November 2003 at the UIC Library of the Health Sciences. Library staff completed an online survey form for each question, and if a client asked more than one question, each question was coded individually. Data included: status of client using the service (faculty/staff. undergarduate student, graduate student, non0UIC, unknown; mode of submission (email, chat, phone, in person; and type of question asked (directional, ready reference, in-depth/mediated, instructional, technical, accounts/status and other. In subsequent analysis, the original seven types of questions were further broken down into 19 categories. Main results - It was not possible to undertake a meta-analysis or systematic review of the studies identified in the literature review because of differences in time frames, settings and the categories used to code reference questions. However the following trends emerged: directional questions accounted for between 30 and 35% of questions asked at both the physical and virtual reference desks; the remainder of questions were generally about known item searched, library policies and services, research, dadabase use and quick reference. The statistics collected at UIC Library of the Health Sciences over the period July 1997 to June 2003 were analyzed. Coded reference questions fell into one of four categories; ready reference, in-depth reference, mediated searched and digital reference. There was a noticeable drop in the number of reference questions received in 1999/2000 which reflects trends reported in some of the studies identified in the literature review. The number of mediated searches decreased from 154 in 1997-98 to 4 in 2002/2003, but the number of digital reference questions increased from 0 to 508 in the same period. Statistics were collected over the month of November 2003 for 939 questions asked at the reference and information desks which included: 38 email; 48 chat; 156 phone; and 697 in person. The major findings were as follows: - appoximately 55% of questions were reference questions (33.5% ready reference, 9.7% in-depth/mediated, 9.7% instructional; 30% were directional; and 10% were technical; it is not stated what the remaining 5% of questions were; - library clients who asked the questions comprised graduate students (26%, faculty (24%, undergraduate students (24% and non-UIC patrons (22%; - all groups were most likely to ask their reference questions in person; - graduate students were the largest group of email reference (34%, undergraduates were the largest group to use chat (35% and faculty/staff were the largest group to use the telephone (39%; - 28% of the questions were answered from the library's staff's general knowledge of the library; 22% using the online catalogue or electronic journals list; 22% by referrning the patron to, or using an online database or resource; 13% by referring the patron to another department in the library (such as circulation; 7% by consulting another individual; and 5% by using print resources. Conclusion - The results of the three parts of this study - literature review, study of 1997-2003 statistics, and in-depth collection of statistics for November 2003 - are difficult to compare with each other. However, the general trend emerging from the results is that some kinds of questions asked by health sciences library clients have remained very much the same regardless of the rise of remote end-user searching and the mode of transmission of the questions. These include questions about library policies and services, journal and book holdings, database searching and instructional support. Questions about citation verification and consumer health appear to be decreasing while technical questions and questions about accessing remote databases and online journals are increasing. The majority of reference questions are still asked in person.

  2. Plate Tectonics: A Paradigm under Threat.

    Science.gov (United States)

    Pratt, David

    2000-01-01

    Discusses the challenges confronting plate tectonics. Presents evidence that contradicts continental drift, seafloor spreading, and subduction. Reviews problems posed by vertical tectonic movements. (Contains 242 references.) (DDR)

  3. Radiochemical determination of the neutron capture cross sections of {sup 241}Am irradiated in the JMTR reactor

    Energy Technology Data Exchange (ETDEWEB)

    Shinohara, N.; Hatsukawa, Y.; Hata, K.; Kohno, N. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    The thermal neutron capture cross section {sigma}{sub 0} and Resonance integral I{sub 0} of {sup 241}Am leading to the production of {sup 242m}Am and {sup 242g}Am were measured by radiochemical method. The cross sections obtained in this study are {sigma}{sub 0}=60.9 {+-} 2.6 barn, I{sub 0}=213 {+-} 13 barn for {sup 241}Am(n,{gamma}){sup 242m}Am and {sigma}{sub 0}=736 {+-} 31 barn, I{sub 0}=1684 {+-} 92 barn for {sup 241}Am(n,{gamma}){sup 242g}Am. (author)

  4. TOWARD AN IMPROVED UNDERSTANDING OF STRUCTURE AND MAGNETISM IN NEPTUNIUM AND PLUTONIUM PHOSPHONATES AND SULFONATES

    Energy Technology Data Exchange (ETDEWEB)

    Albrecht-Schmitt, Thomas

    2012-03-01

    This grant supported the exploratory synthesis of new actinide materials with all of the actinides from thorium to californium with the exceptions of protactinium and berkelium. We developed detailed structure-property relationships that allowed for the identification of novel materials with selective ion-exchange, selective oxidation, and long-range magnetic ordering. We found novel bonding motifs and identified periodic trends across the actinide series. We identified structural building units that would lead to desired structural features and novel topologies. We also characterized many different spectroscopic trends across the actinide series. The grant support the preparation of approximately 1200 new compounds all of which were structurally characterized.

  5. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  6. NONDESTRUCTIVE IDENTIFICATION OF CHEMICAL WARFARE AGENTS AND EXPLOSIVES BY NEUTRON GENERATOR-DRIVEN PGNAA

    Energy Technology Data Exchange (ETDEWEB)

    T. R. Twomey; A. J. Caffrey; D. L. Chichester

    2007-02-01

    Prompt gamma-ray neutron activation analysis (PGNAA) is now a proven method for the identification of chemical warfare agents and explosives in military projectiles and storage containers. Idaho National Laboratory is developing a next-generation PGNAA instrument based on the new Ortec Detective mechanically-cooled HPGe detector and a neutron generator. In this paper we review PGNAA analysis of suspect chemical warfare munitions, and we discuss the advantages and disadvantages of replacing the californium-252 radioisotopic neutron source with a compact accelerator neutron generator.

  7. An ECR Charge Breeder for the 252 Cf Fission Source Project (CARIBU) at ATLAS%ATLAS用于CARIBU项目的ECR离子剥离器

    Institute of Scientific and Technical Information of China (English)

    R.C.Pardo; R.Vondrasek; T.Kulevoy; V.Aseev; R.Scott; P.Suominen

    2007-01-01

    A new radioactive beam facility for ATLAS,the Californium Rare Ion Breeder Upgrade(CARIBU),is under construction.The facility will use fission fragments from a 1 Ci 252 Cf source;thermalized and collected into a low-energy beam by a helium gas catcher.In order to reaccelerate these beams.the existing ATLAS ECR-I ion source is being redesigned to function as a charge breeder source.The design and features of this charge breeder configuration is discussed and the project status described.

  8. Advanced development of the spectrum sciences Model 5005-TF, single-event test fixture

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, M.R.; Browning, J.S. (Sandia National Labs., Albuquerque, NM (USA)); Hughlock, B.W. (Boeing Aerospace and Electronics Co., Seattle, WA (USA)); Lum, G.K. (Lockheed Missiles and Space Co., Sunnyvale, CA (USA)); Tsacoyeanes, W.C. (Draper (Charles Stark) Lab., Inc., Cambridge, MA (USA)); Weeks, M.D. (Spectrum Sciences, Inc., Santa Clara, CA (USA))

    1990-09-01

    This report summarizes the advanced development of the Spectrum Sciences Model 5005-TF, Single-Event Test Fixture. The Model 5005-TF uses a Californium-252 (Cf-252) fission-fragment source to test integrated circuits and other devices for the effects of single-event phenomena. Particle identification methods commonly used in high-energy physics research and nuclear engineering have been incorporated into the Model 5005-TF for estimating the particle charge, mass, and energy parameters. All single-event phenomena observed in a device under test (DUT) are correlated with an identified fission fragment, and its linear energy transfer (LET) and range in the semiconductor material of the DUT.

  9. Method for measuring multiple scattering corrections between liquid scintillators

    Science.gov (United States)

    Verbeke, J. M.; Glenn, A. M.; Keefer, G. J.; Wurtz, R. E.

    2016-07-01

    A time-of-flight method is proposed to experimentally quantify the fractions of neutrons scattering between scintillators. An array of scintillators is characterized in terms of crosstalk with this method by measuring a californium source, for different neutron energy thresholds. The spectral information recorded by the scintillators can be used to estimate the fractions of neutrons multiple scattering. With the help of a correction to Feynman's point model theory to account for multiple scattering, these fractions can in turn improve the mass reconstruction of fissile materials under investigation.

  10. PROCEEDINGS OF THE SYMPOSIUM COMMEMORATING THE 25th ANNIVERSARY OF ELEMENTS 97 and 98 HELD ON JAN. 20, 1975

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, Glenn T.; Street Jr., Kenneth; Thompson, Stanley G.; Ghiorso, Albert

    1976-07-01

    This volume includes the talks given on January 20, 1975, at a symposium in Berkeley on the occasion of the celebration of the 25th anniversary of the discovery of berkelium and californium. Talks were given at this symposium by the four people involved in the discovery of these elements and by a number of people who have made significant contributions in the intervening years to the investigation of their nuclear and chemical properties. The papers are being published here, without editing, in the form in which they were submitted by the authors in the months following the anniversary symposium, and they reflect rather faithfully the remarks made on that occasion.

  11. 49 CFR 24.101 - Applicability of acquisition requirements.

    Science.gov (United States)

    2010-10-01

    ... such properties are not displaced persons, (see §§ 24.2(a)(9)(ii)(E) or (H)), and as such, are not... paragraphs (b)(1) through (5) of this section. Such tenants are considered displaced persons. (See § 24.2(a... projects undertaken by an Agency or person that receives Federal financial assistance but does not...

  12. 10 CFR Appendix L to Part 110 - Illustrative List of Byproduct Materials Under NRC Export/Import Licensing Authority a

    Science.gov (United States)

    2010-01-01

    ... 137) Chlorine 36 (Cl 36) Chlorine 38 (Cl 38) Chromium 51 (Cr 51) Cobalt 58m (Co 58m) Cobalt 58 (Co 58) Cobalt 60 (Co 60) Copper 64 (Cu 64) Curium 240 (Cm 240) Curium 241 (Cm 241) Curium 242 (Cm 242)...

  13. 75 FR 4963 - Federal Housing Administration (FHA): Hospital Mortgage Insurance Program-Refinancing Hospital Loans

    Science.gov (United States)

    2010-01-29

    ... Housing and Urban Development 24 CFR Part 242 Federal Housing Administration (FHA): Hospital Mortgage Insurance Program--Refinancing Hospital Loans; Proposed Rule #0;#0;Federal Register / Vol. 75 , No. 19... 242 RIN 2502-AI74 Federal Housing Administration (FHA): Hospital Mortgage Insurance...

  14. 17 CFR 270.17a-7 - Exemption of certain purchase or sale transactions between an investment company and certain...

    Science.gov (United States)

    2010-04-01

    ... such exchange that day; or (3) If the security is not a reported security and is quoted in the NASDAQ...: (1) If the security is an “NMS stock” as that term is defined in 17 CFR 242.600, the last sale price... such security (reported pursuant to 17 CFR 242.602) if there are no reported transactions in...

  15. Military Policy toward Homosexuals: Scientific, Historic, and Legal Perspectives

    Science.gov (United States)

    1990-04-01

    drugs include chlorimipramine, diazepam , diethylstilbesterol (DES), pargyline, and reserpine. 31. Id. at 242. 32. Id. at 242. 33. Id. at 243. 34. Id...35. Id. at 244-47. The four types are 5 alphareductase deficiency, androgen insensitivity syndrome, faulty testosterone synthesis, and congenital

  16. 75 FR 32555 - Consolidated Audit Trail

    Science.gov (United States)

    2010-06-08

    ... Exchange Commission 17 CFR Part 242 Consolidated Audit Trail; Proposed Rule #0;#0;Federal Register / Vol... CFR Part 242 RIN 3235-AK51 Consolidated Audit Trail AGENCY: Securities and Exchange Commission. ACTION... maintain a consolidated order tracking system, or consolidated audit trail, with respect to the trading...

  17. Drug: D04002 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04002 Drug Enofelast (USAN/INN) C16H15FO 242.1107 242.2881 D04002.gif Anti-asthmat...ic CAS: 127035-60-3 PubChem: 17397997 LigandBox: D04002 NIKKAJI: J328.571E ATOM 18 1 C8y C 27.3895 -19.4789

  18. Dicty_cDB: Contig-U11690-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available = 190/190 (100%) Strand = Plus / Plus Query: 182 gatgnagatatcnttcaaagatttaatccnattagnntggtcntttcnatnaaaccna...aa 241 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 182 gatgnagatatcnttcaaagatttaatccna...ttagnntggtcntttcnatnaaaccnaaa 241 Query: 242 tnggattnntcnattaggccatatnttttnaaan... = 9e-41 Identities = 189/189 (100%) Strand = Plus / Minus Query: 183 atgnagatatcnttcaaagatttaatccna...ttagnntggtcntttcnatnaaaccnaaat 242 ||||||||||||||||||||||||||||||||||||||||||||||||||||||

  19. Improved charge breeding efficiency of light ions with an electron cyclotron resonance ion source

    Energy Technology Data Exchange (ETDEWEB)

    Vondrasek, R.; Kutsaev, Sergey [Argonne National Laboratory, Argonne, Illinois 60439 (United States); Delahaye, P.; Maunoury, L. [Grand Accelerateur National d' Ions Lourds (GANIL), CEA/DSM-CNRS/IN2P3, Blvd Henri Becquerel, 14076 Caen (France)

    2012-11-15

    The Californium Rare Isotope Breeder Upgrade is a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS). The facility utilizes a {sup 252}Cf fission source coupled with an electron cyclotron resonance ion source to provide radioactive beam species for the ATLAS experimental program. The californium fission fragment distribution provides nuclei in the mid-mass range which are difficult to extract from production targets using the isotope separation on line technique and are not well populated by low-energy fission of uranium. To date the charge breeding program has focused on optimizing these mid-mass beams, achieving high charge breeding efficiencies of both gaseous and solid species including 14.7% for the radioactive species {sup 143}Ba{sup 27+}. In an effort to better understand the charge breeding mechanism, we have recently focused on the low-mass species sodium and potassium which up to present have been difficult to charge breed efficiently. Unprecedented charge breeding efficiencies of 10.1% for {sup 23}Na{sup 7+} and 17.9% for {sup 39}K{sup 10+} were obtained injecting stable Na{sup +} and K{sup +} beams from a surface ionization source.

  20. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin

    Directory of Open Access Journals (Sweden)

    Seok-Hyung Kim

    2011-03-01

    Tuberous sclerosis complex (TSC is an autosomal dominant disease caused by mutations in either the TSC1 (encodes hamartin or TSC2 (encodes tuberin genes. Patients with TSC have hamartomas in various organs throughout the whole body, most notably in the brain, skin, eye, heart, kidney and lung. To study the development of hamartomas, we generated a zebrafish model of TSC featuring a nonsense mutation (vu242 in the tsc2 gene. This tsc2vu242 allele encodes a truncated Tuberin protein lacking the GAP domain, which is required for inhibition of Rheb and of the TOR kinase within TORC1. We show that tsc2vu242 is a recessive larval-lethal mutation that causes increased cell size in the brain and liver. Greatly elevated TORC1 signaling is observed in tsc2vu242/vu242 homozygous zebrafish, and is moderately increased in tsc2vu242/+ heterozygotes. Forebrain neurons are poorly organized in tsc2vu242/vu242 homozygous mutants, which have extensive gray and white matter disorganization and ectopically positioned cells. Genetic mosaic analyses demonstrate that tsc2 limits TORC1 signaling in a cell-autonomous manner. However, in chimeric animals, tsc2vu242/vu242 mutant cells also mislocalize wild-type host cells in the forebrain in a non-cell-autonomous manner. These results demonstrate a highly conserved role of tsc2 in zebrafish and establish a new animal model for studies of TSC. The finding of a non-cell-autonomous function of mutant cells might help explain the formation of brain hamartomas and cortical malformations in human TSC.

  1. Toward Reanalysis of the Tight-Pitch HCLWR-PROTEUS Phase II Experiments

    Directory of Open Access Journals (Sweden)

    Perret Grégory

    2016-01-01

    Spectral index predictions using the three nuclear data libraries agreed within two standard deviations with the measured values. The only exception is the Pu-242-capture-to-Pu-239-fission ratio, which was overestimated with all libraries by more than four standard deviations, i.e. 13%, in the non-moderated configuration. In this configuration, Pu-242 captures are few since the flux spectrum in the Pu-242 capture resonance region (between 1eV and 1keV is small making this spectral index hard to measure. Sensitivity coefficient predictions with both MCNP6 and SERPENT2 were in good agreement.

  2. Socialization Values and Parenting Practices as Predictors of Parental Involvement in Their Children's Educational Process

    NARCIS (Netherlands)

    Kikas, Eve; Tulviste, Tiia; Peets, Kätlin

    2014-01-01

    Research Findings: The purpose of this study was to examine associations between parental socialization values (including inconsistency in values), parenting practices, and parental involvement in their children's education. Altogether 242 Estonian mothers and fathers of first-grade children partici

  3. Disease: H01309 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H, Tanizaki H, Heike T, Miyachi Y, Nakahata T Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis. Arthritis Rheum 60:242-50 (2009) ...

  4. Fritz-Peter Hager/Daniel Tröhler (Hrsg.): Neue Pestalozzi-Studien. Bd. 1: Anna Pestalozzis Tagebuch - Käte Silber: Anna Pestalozzi und der Frauenkreis um Pestalozzi. Bern/Stuttgart: Haupt 1993 [Rezension

    OpenAIRE

    Liedtke, Max

    1994-01-01

    Rezension von: Fritz-Peter Hager/Daniel Tröhler (Hrsg.): Neue Pestalozzi-Studien. Bd. 1: Anna Pestalozzis Tagebuch - Käte Silber: Anna Pestalozzi und der Frauenkreis um Pestalozzi. Bern/Stuttgart: Haupt 1993, 242 S.

  5. 29 CFR 780.137 - Practices must be performed in connection with farmer's own farming.

    Science.gov (United States)

    2010-07-01

    ... Co., 242 F. 2d 714; Mitchell v. Huntsville Nurseries, 267 F. 2d 286; Bowie v. Gonzalez, 117 F. 2d 11... (Mitchell v. Huntsville Nurseries, supra; Farmers Reservoir Co. v. McComb, supra; Bowie v. Gonzalez, supra)....

  6. Geraldien von Frijtag Drabbe Künzel, Hitlers broedervolk. De Nederlandse bijdrage aan de kolonisatiepolitiek van de nazi’s in Oost-Europa

    Directory of Open Access Journals (Sweden)

    Jan Julia Zurné

    2016-11-01

    Full Text Available Geraldien von Frijtag Drabbe Künzel, Hitlers broedervolk. De Nederlandse bijdrage aan de kolonisatiepolitiek van de nazi’s in Oost-Europa (Amsterdam: Prometheus, 2016, 242 pp., isbn 978 90 351 4396 8.

  7. Band pass filters. Citations from the NTIS data base

    Science.gov (United States)

    Reed, W. E.

    1980-04-01

    A bibliography containing 242 abstracts addressing the design, fabrication, characterization, and application of band pass filters is presented. Radiofrequency, digital, acoustic surface wave, and X-ray filters are included.

  8. GETDB: 112973 [GETDB

    Lifescience Database Archive (English)

    Full Text Available rsal, ventral) tr, fb tarsal ring, al, eye, tarsas - - comment1:A, comment2:42F2-...l tarsal ring, al, Adult GFP eye, tarsas Lethality - Also known as - Original Comments comment1:A, comment2:

  9. 75 FR 25895 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of a Proposed Rule...

    Science.gov (United States)

    2010-05-10

    ... Horton Inc. 223 WMB Williams Cos Inc./The..... 280 ADBE Adobe Systems Inc. 225 MEE Massey Energy Co 281... Radio Inc. 241 SII Smith International Inc... 291 MMR McMoRan Exploration Co. 242 RTN Raytheon Co...

  10. 75 FR 25890 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-05-10

    .... Corp. 220 DTV DIRECTV......... 279 DHI DR Horton Inc. 223 WMB Williams Cos Inc/ 280 ADBE Adobe Systems... Sirius XM Radio The. Inc. 241 SII Smith 291 MMR McMoRan International Exploration Co. Inc. 242...

  11. 75 FR 26312 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing and Immediate Effectiveness of...

    Science.gov (United States)

    2010-05-11

    .... 220 DTV DIRECTV. 279 DHI DR Horton Inc. 223 WMB Williams Cos Inc/The. 280 ADBE Adobe Systems Inc. 225... XM Radio Inc. 241 SII Smith International 291 MMR McMoRan Exploration Inc. Co. 242 RTN Raytheon...

  12. 26 CFR 1.401(a)(9)-8 - Special rules.

    Science.gov (United States)

    2010-04-01

    ... before January 1, 1984, in accordance with section 242(b)(2) of the Tax Equity and Fiscal Responsibility... by the transferee plan. (c) A merger, spinoff, or consolidation, as defined in § 1.414(l)-1(b),...

  13. 76 FR 69801 - Conductor Certification

    Science.gov (United States)

    2011-11-09

    ... definition of ``conductor'' is a fundamental element of the conductor certification regulation and FRA does... and 219. G. Vision and Hearing Acuity BLET/UTU commented that proposed Sec. 242.117(k) should...

  14. CPAP Tips

    Medline Plus

    Full Text Available ... navigation Sign in Search Loading... Close Yeah, keep it Undo Close This video is unavailable. Watch Queue ... Why CPAP Sucks and What to Do About It - Duration: 8:46. apapuser 242,319 views 8: ...

  15. Gravity Data for the State of New Mexico

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The gravity station data (21,242 records) were compiled by the University of Texas at El Paso. This data base was received in October 1984. Principal gravity...

  16. Self-reported early trauma as a predictor of adult personality : A study in a military sample

    NARCIS (Netherlands)

    Rademaker, Arthur R.; Vermetten, Eric; Geuze, Elbert; Muilwilk, Anne; Kleber, Rolf J.

    2008-01-01

    Exposure to early trauma has frequently been linked to adult psychopathology, including personality disorders. This cross-sectional study explored the relationship between personality and retrospectively rated levels of early trauma in 242 soldiers. Multiple regression analyses showed a significant

  17. State-dependent blocker interactions with the CFTR chloride channel: implications for gating the pore.

    Science.gov (United States)

    Linsdell, Paul

    2014-12-01

    Chloride permeation through the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel is subject to voltage-dependent open-channel block by a diverse range of cytoplasmic anions. However, in most cases the ability of these blocking substances to influence the pore opening and closing process has not been reported. In the present work, patch clamp recording was used to investigate the state-dependent block of CFTR by cytoplasmic Pt(NO2)4(2-) ions. Two major effects of Pt(NO2)4(2-) were identified. First, this anion caused fast, voltage-dependent block of open channels, leading to an apparent decrease in single-channel current amplitude. Secondly, Pt(NO2)4(2-) also decreased channel open probability due to an increase in interburst closed times. Interestingly, mutations in the pore that weakened (K95Q) or strengthened (I344K, V345K) interactions with Pt(NO2)4(2-) altered blocker effects both on Cl(-) permeation and on channel gating, suggesting that both these effects are a consequence of Pt(NO2)4(2-) interaction with a single site within the pore. Experiments at reduced extracellular Cl(-) concentration hinted that Pt(NO2)4(2-) may have a third effect, possibly increasing channel activity by interfering with channel closure. These results suggest that Pt(NO2)4(2-) can enter from the cytoplasm into the pore inner vestibule of both open and closed CFTR channels, and that Pt(NO2)4(2-) bound in the inner vestibule blocks Cl(-) permeation as well as interfering with channel opening and, perhaps, channel closure. Implications for the location of the channel gate in the pore, and the operation of this gate, are discussed.

  18. Tumor markers for diagnosis, monitoring of recurrence and prognosis in patients with upper gastrointestinal tract cancer.

    Science.gov (United States)

    Jing, Jie-Xian; Wang, Yan; Xu, Xiao-Qin; Sun, Ting; Tian, Bao-Guo; Du, Li-Li; Zhao, Xian-Wen; Han, Cun-Zhi

    2014-01-01

    To evaluate the value of combined detection of serum CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS for the clinical diagnosis of upper gastrointestinal tract (GIT) cancer and to analyze the efficacy of these tumor markers (TMs) in evaluating curative effects and prognosis. A total of 573 patients with upper GIT cancer between January 2004 and December 2007 were enrolled in this study. Serum levels of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were examined preoperatively and every 3 months postoperatively by ELISA. The sensitivity of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were 26.8%, 36.2%, 42.9%, 2.84%, 25.4%, 34.6%, 34.2% and 30.9%, respectively. The combined detection of CEA+CA199+CA242+CA724 had higher sensitivity and specificity in gastric cancer (GC) and cardiac cancer, while CEA+CA199+CA242+SCC was the best combination of diagnosis for esophageal cancer (EC). Elevation of preoperative CEA, CA19-9 and CA24-2, SCC and CA72-4 was significantly associated with pathological types (pdiagnosis of EC; CEA+CA199+CA242+CA724 proved to be a better evaluation indicator for cardiac cancer and GC. CEA and CA19-9, CA24-2, CA72-4 and SCC, examined postoperatively during follow-up, were useful to find early tumor recurrence and metastasis, and evaluate prognosis. AFP, TPA and TPS have no significant value in diagnosis of patients with upper GIT cancer.

  19. Population Consequences of Acoustic Disturbance of Blainville’s Beaked Whales at AUTEC

    Science.gov (United States)

    2014-09-30

    Charlotte Ann Dunn Bahamas Marine Mammal Research Organisation P.O. Box AB-20714 Marsh Harbour Abaco, Bahamas phone: (242) 366-4155 fax: (242...N000141210213 http://www.bahamaswhales.org LONG-TERM GOALS Atypical strandings and behavioral responses of beaked whales have been associated...2011). Yet MFA sonar operations occur repeatedly on Navy ranges that are known beaked whale habitat. The Bahamas Marine Mammal Research Organisation

  20. Beaked Whale Group Deep Dive Behavior from Passive Acoustic Monitoring

    Science.gov (United States)

    2015-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Beaked Whale Group Deep Dive Behavior from Passive...Research Organisation P.O. Box AB-20714 Marsh Harbour Abaco, Bahamas phone: (242) 366-4155 fax: (242) 366-4155 email: dclaridge...N000141512649 LONG-TERM GOALS While a significant body of knowledge regarding individual beaked whale behavior at depth has been established in the

  1. Sticky-Finger Manipulation with a Multi-Touch Interface

    Science.gov (United States)

    2011-07-01

    16 2.4.2 Simple Shape Gesture Recognition . . . . . . . . . . . . . . . . . . . . . 17 vii 2.4.3 Collision...system. Depending on the multi-touch hardware used, the area and shape of each finger that 16 Figure 2.10: Simple Rectangle Gesture Recognition : The...to the capacitive touch-screen of the Ipad, which allows us to achieve consistent and robust results. 2.4.2 Simple Shape Gesture Recognition In

  2. EST Table: FS916464 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS916464 E_FL_fufe_38G11_F_0 10/09/28 54 %/242 aa ref|XP_972061.1| PREDICTED: similar to thymus... 10/09/10 58 %/212 aa gnl|Amel|GB19831-PA 10/09/10 54 %/242 aa gi|91078858|ref|XP_972061.1| PREDICTED: similar to thymus-specific serine protease [Tribolium castaneum] FS916293 fufe ...

  3. Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity1

    Science.gov (United States)

    Hayman, Thomas J; Kramp, Tamalee; Kahn, Jenna; Jamal, Muhammad; Camphausen, Kevin; Tofilon, Philip J

    2013-01-01

    The mechanistic target of rapamycin (mTOR) is a critical kinase in the regulation of gene translation and has been suggested as a potential target for radiosensitization. The goal of this study was to compare the radiosensitizing activities of the allosteric mTOR inhibitor rapamycin with that of the competitive mTOR inhibitor PP242. On the basis of immunoblot analyses, whereas rapamycin only partially inhibited mTOR complex 1 (mTORC1) activity and had no effect on mTOR complex 2 (mTORC2), PP242 inhibited the activity of both mTOR-containing complexes. Irradiation alone had no effect on mTORC1 or mTORC2 activity. Clonogenic survival was used to define the effects of the mTOR inhibitors on in vitro radiosensitivity. In the two tumor cell lines evaluated, PP242 treatment 1 hour before irradiation increased radiosensitivity, whereas rapamycin had no effect. Addition of PP242 after irradiation also enhanced the radiosensitivity of both tumor lines. To investigate the mechanism of radiosensitization, the induction and repair of DNA double-strand breaks were evaluated according γH2AX foci. PP242 exposure did not influence the initial level of γH2AX foci after irradiation but did significantly delay the dispersal of radiation-induced γH2AX foci. In contrast to the tumor cell lines, the radiosensitivity of a normal human fibroblast cell line was not influenced by PP242. Finally, PP242 administration to mice bearing U251 xenografts enhanced radiation-induced tumor growth delay. These results indicate that in a preclinical tumor model PP242 enhances tumor cell radiosensitivity both in vitro and in vivo and suggest that this effect involves an inhibition of DNA repair. PMID:23730416

  4. Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity.

    Science.gov (United States)

    Hayman, Thomas J; Kramp, Tamalee; Kahn, Jenna; Jamal, Muhammad; Camphausen, Kevin; Tofilon, Philip J

    2013-06-01

    The mechanistic target of rapamycin (mTOR) is a critical kinase in the regulation of gene translation and has been suggested as a potential target for radiosensitization. The goal of this study was to compare the radiosensitizing activities of the allosteric mTOR inhibitor rapamycin with that of the competitive mTOR inhibitor PP242. On the basis of immunoblot analyses, whereas rapamycin only partially inhibited mTOR complex 1 (mTORC1) activity and had no effect on mTOR complex 2 (mTORC2), PP242 inhibited the activity of both mTOR-containing complexes. Irradiation alone had no effect on mTORC1 or mTORC2 activity. Clonogenic survival was used to define the effects of the mTOR inhibitors on in vitro radiosensitivity. In the two tumor cell lines evaluated, PP242 treatment 1 hour before irradiation increased radiosensitivity, whereas rapamycin had no effect. Addition of PP242 after irradiation also enhanced the radiosensitivity of both tumor lines. To investigate the mechanism of radiosensitization, the induction and repair of DNA double-strand breaks were evaluated according γH2AX foci. PP242 exposure did not influence the initial level of γH2AX foci after irradiation but did significantly delay the dispersal of radiation-induced γH2AX foci. In contrast to the tumor cell lines, the radiosensitivity of a normal human fibroblast cell line was not influenced by PP242. Finally, PP242 administration to mice bearing U251 xenografts enhanced radiation-induced tumor growth delay. These results indicate that in a preclinical tumor model PP242 enhances tumor cell radiosensitivity both in vitro and in vivo and suggest that this effect involves an inhibition of DNA repair.

  5. Triton and alpha-particle contribution from LiF converter for neutron dosimeter

    CERN Document Server

    Camacho, M E; Balcazar, M

    1999-01-01

    A personnel neutron dosimeter prototype based on chemical and electrochemical etched CR-39 detector, combined with LiF converter, has been calibrated using an ICRP-like phantom, under a heavy-water moderated Californium source neutron spectra; A conversion factor of 1.052+-126 spots cm sup - sup 2 mSv sup - sup 1 was obtained. The sealing properties of the detector holder showed a ten-fold reduction in radon background when it was tested in a high radon atmosphere. A convenient mechanical shock resistance was achieved in LiF converters by sintering to 11 tons pressure LiF powder at 650 deg. C, during one hour.

  6. Reliability of semiconductor and gas-filled diodes for over-voltage protection exposed to ionizing radiation

    Directory of Open Access Journals (Sweden)

    Stanković Koviljka

    2009-01-01

    Full Text Available The wide-spread use of semiconductor and gas-filled diodes for non-linear over-voltage protection results in a variety of possible working conditions. It is therefore essential to have a thorough insight into their reliability in exploitation environments which imply exposure to ionizing radiation. The aim of this paper is to investigate the influence of irradiation on over-voltage diode characteristics by exposing the diodes to californium-252 combined neutron/gamma radiation field. The irradiation of semiconductor over-voltage diodes causes severe degradation of their protection characteristics. On the other hand, gas-filled over-voltage diodes exhibit a temporal improvement of performance. The results are presented with the accompanying theoretical interpretations of the observed changes in over-voltage diode behaviour, based on the interaction of radiation with materials constituting the diodes.

  7. First results from the CARIBU facility: mass measurements on the r-process path.

    Science.gov (United States)

    Van Schelt, J; Lascar, D; Savard, G; Clark, J A; Bertone, P F; Caldwell, S; Chaudhuri, A; Levand, A F; Li, G; Morgan, G E; Orford, R; Segel, R E; Sharma, K S; Sternberg, M G

    2013-08-09

    The Canadian Penning Trap mass spectrometer has made mass measurements of 33 neutron-rich nuclides provided by the new Californium Rare Isotope Breeder Upgrade facility at Argonne National Laboratory. The studied region includes the 132Sn double shell closure and ranges in Z from In to Cs, with Sn isotopes measured out to A=135, and the typical measurement precision is at the 100 ppb level or better. The region encompasses a possible major waiting point of the astrophysical r process, and the impact of the masses on the r process is shown through a series of simulations. These first-ever simulations with direct mass information on this waiting point show significant increases in waiting time at Sn and Sb in comparison with commonly used mass models, demonstrating the inadequacy of existing models for accurate r-process calculations.

  8. Nuclear fission and the transuranium elements

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, G.T.

    1989-02-01

    Many of the transuranium elements are produced and isolated in large quantities through the use of neutrons furnished by nuclear fission reactions: plutonium (atomic number 94) in ton quantities; neptunium (93), americium (95), and curium (96) in kilogram quantities; berkelium (97) in 100 milligram quantities; californium (98) in gram quantities; and einsteinium (99) in milligram quantities. Transuranium isotopes have found many practical applications---as nuclear fuel for the large-scale generation of electricity, as compact, long-lived power sources for use in space exploration, as means for diagnosis and treatment in the medical area, and as tools in numerous industrial processes. Of particular interest is the unusual chemistry and impact of these heaviest elements on the periodic table. This account will feature these aspects. 9 refs., 5 figs.

  9. Production of highly pure einsteinium and fermium preparations

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, O.I.; Tarasov, V.A.; Zotov, E.A.; Baranov, A.Yu. [Federal State Unitary Enterprise ' ' State Scientific Center of Russian Federation Research Institute of Atomic Reactors' ' (Russian Federation)

    2004-07-01

    Highly pure einsteinium and fermium preparations are in increased demand due to the progress of the following fields of modern sciences: Fundamental and applied nuclear physics. Heavy actinides are necessary for detailed study of structure and decay of a nucleus, as well as initial material both for nuclear synthesis of new superheavy elements and for manufacturing radioactive radiation sources. Fundamental and applied radiochemistry. Einsteinium and fermium preparations are required to investigate chemical properties of these hard-to-obtain elements and to improve technology of their recovery and purification. Nuclear medicine. Biologically active compounds labeled with alpha- emitting einsteinium and fermium may be applied in prospect for a radioimmunotherapy of oncological diseases. The principal method of einsteinium and fermium production is irradiation of curium or californium isotopes in a high-flux nuclear reactor. Large-scale production of transplutonium elements at RIAR enables also to produce regularly significant quantities of einsteinium and fermium. (orig.)

  10. Beta-delayed neutron spectroscopy using ion traps

    Science.gov (United States)

    Wang, Barbara; Czeszumska, A.; Siegl, K.; Caldwell, S.; Aprahamian, A.; Burkey, M.; Clark, J.; Levand, A.; Marley, S.; Morgan, G.; Norman, E.; Nystrom, A.; Orford, R.; Padgett, S.; Perez Galvan, A.; Savard, G.; Scielzo, N.; Sharma, K.; Strauss, S.

    2017-01-01

    Trapped radioactive ions suspended in vacuum allow for a new way to perform beta-delayed neutron spectroscopy. Decay branching ratios and energy spectra of the emitted neutrons are inferred from a measurement of the nuclear recoil, thereby circumventing the many limitations associated with direct neutron detection. Beta-delayed neutron measurements were carried out for 137-138,140I, 134-136Sb, and 144-145Cs at the Californium Rare Isotope Breeder Upgrade (CARIBU) facility at Argonne National Laboratory. The data collected are needed in many fields of basic and applied science such as nuclear energy, nuclear astrophysics, and stockpile stewardship. Results for the isotopes 135-136Sb and 140I will be presented. Supported by NSF under PHY-1419765, and U.S. DOE under NEUP 13-5485, DE-AC02-06CH11357 (ANL), DE-AC52-07NA27344 (LLNL), and DE-NA0000979 (NNSA).

  11. Environmental assessment of the thermal neutron activation explosive detection system for concourse use at US airports

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.G.

    1990-08-01

    This document is an environmental assessment of a system designed to detect the presence of explosives in checked airline baggage or cargo. The system is meant to be installed at the concourse or lobby ticketing areas of US commercial airports and uses a sealed radioactive source of californium-252 to irradiate baggage items. The major impact of the use of this system arises from direct exposure of the public to scattered or leakage radiation from the source and to induced radioactivity in baggage items. Under normal operation and the most likely accident scenarios, the environmental impacts that would be created by the proposed licensing action would not be significant. 44 refs., 19 figs., 18 tabs.

  12. TRIGA-TRAP: A penning trap mass spectrometer at the research reactor TRIGA Mainz

    Energy Technology Data Exchange (ETDEWEB)

    Smorra, Christian [Physikalisches Institut, Universitaet Heidelberg (Germany); Institut fuer Kernchemie, Universitaet Mainz (Germany); Blaum, Klaus [Physikalisches Institut, Universitaet Heidelberg (Germany); Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Block, Michael; Herfurth, Frank [GSI, Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Eberhardt, Klaus [Institut fuer Kernchemie, Universitaet Mainz (Germany); Eibach, Martin; Ketelaer, Jens; Ketter, Jochen; Knuth, Konstantin; Repp, Julia [Institut fuer Physik, Universitaet Mainz (Germany); Nagy, Szilard [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)

    2009-07-01

    Nuclear masses represent the binding energies and, therefore, the sum of all interactions in the nucleus. They provide an important input parameter to nuclear structure models. Presently, a tremendous interest in masses of very exotic neutron-rich nuclides exists to support theoretical models for the nucleosynthesis via the rapid neutron capture process. The research reactor TRIGA Mainz provides access to a large variety of neutron-rich nuclides produced by thermal-neutron induced fission of an actinide target. The double-Penning trap mass spectrometer TRIGA-TRAP will perform high-precision mass measurements in this region of the nuclear chart as well as on actinides from uranium to californium. It also serves as a test facility for the development of new techniques that will be implemented in future facilities like MATS at FAIR (GSI, Darmstadt). The layout of TRIGA-TRAP as well as recent mass measurements are presented.

  13. Populations of selected microbial and fungal species growing on the surface of rape seeds following treatment with desiccants or plant growth regulators.

    Science.gov (United States)

    Frac, Magdalena; Jezierska-Tys, Stefania; Tys, Jerzy

    2010-01-01

    The aim of this study was to determine the effects of desiccants and plant growth regulators on selected microbial species affecting rape seeds, with special emphasis on the growth of fungi and identification of the genus and species composition. The experimental material in the study was seeds of winter rape cv. Californium that were collected from the field during combine harvest. The chemical agents applied, both desiccants and growth regulators, generally decreased the populations of bacteria occurring on the surface of rape seeds. The responses of fungi depended upon the type of agent applied and were manifested as either stimulation or inhibition of the growth of the fungal species. The fungi isolated from the surface of rape seeds were characteristic of those found in the field environment (Cladosporium and Penicillium) and typical for those present on the surface of rape seeds (Alternaria).

  14. Measurements of the neutron capture cross sections and incineration potentials of minor-actinides in high thermal neutron fluxes: Impact on the transmutation of nuclear wastes; Mesures des sections efficaces de capture et potentiels d'incineration des actinides mineurs dans les hauts flux de neutrons: Impact sur la transmutation des dechets

    Energy Technology Data Exchange (ETDEWEB)

    Bringer, O

    2007-10-15

    This thesis comes within the framework of minor-actinide nuclear transmutation studies. First of all, we have evaluated the impact of minor actinide nuclear data uncertainties within the cases of {sup 241}Am and {sup 237}Np incineration in three different reactor spectra: EFR (fast), GT-MHR (epithermal) and HI-HWR (thermal). The nuclear parameters which give the highest uncertainties were thus highlighted. As a result of fact, we have tried to reduce data uncertainties, in the thermal energy region, for one part of them through experimental campaigns in the moderated high intensity neutron fluxes of ILL reactor (Grenoble). These measurements were focused onto the incineration and transmutation of the americium-241, the curium-244 and the californium-249 isotopes. Finally, the values of 12 different cross sections and the {sup 241}Am isomeric branching ratio were precisely measured at thermal energy point. (author)

  15. 241Am (n,gamma) isomer ratio measurement

    Energy Technology Data Exchange (ETDEWEB)

    Bond, Evelyn M [Los Alamos National Laboratory; Vieira, David J [Los Alamos National Laboratory; Moody, Walter A [Los Alamos National Laboratory; Slemmons, Alice K [Los Alamos National Laboratory

    2011-01-05

    The objective of this project is to improve the accuracy of the {sup 242}Cm/{sup 241}Am radiochemistry ratio. We have performed an activation experiment to measure the {sup 241}Am(n,{gamma}) cross section leading to either the ground state of {sup 242g}Am (t{sub 1/2} = 16 hr) which decays to {sup 242}Cm (t{sub 1/2} = 163 d) or the long-lived isomer {sup 242m}Am (t{sub 1/2} = 141 yr). This experiment will develop a new set of americium cross section evaluations that can be used with a measured {sup 242}Cm/{sup 241}Am radiochemical measurement for nuclear forensic purposes. This measurement is necessary to interpret the {sup 242}Cm/{sup 241}Am ratio because a good measurement of this neutron capture isomer ratio for {sup 241}Am does not exist. The targets were prepared in 2007 from {sup 241}Am purified from LANL stocks. Gold was added to the purified {sup 241}Am as an internal neutron fluence monitor. These targets were placed into a holder, packaged, and shipped to Forschungszentrum Karlsruhe, where they were irradiated at their Van de Graff facility in February 2008. One target was irradiated with {approx}25 keV quasimonoenergetic neutrons produced by the {sup 7}Li(p,n) reaction for 3 days and a second target was also irradiated for 3 days with {approx}500 keV neutrons. Because it will be necessary to separate the {sup 242}Cm from the {sup 241}Am in order to measure the amount of {sup 242}Cm by alpha spectrometry, research into methods for americium/curium separations were conducted concurrently. We found that anion exchange chromatography in methanol/nitric acid solutions produced good separations that could be completed in one day resulting in a sample with no residue. The samples were returned from Germany in July 2009 and were counted by gamma spectrometry. Chemical separations have commenced on the blank sample. Each sample will be spiked with {sup 244}Cm, dissolved and digested in nitric acid solutions. One third of each sample will be processed at a time

  16. 血清肿瘤标志物联合检测在胰腺癌诊断中的应用价值%Application of combined test for serum tumor markers in diagnosis of pancreatic adenocarcinoma

    Institute of Scientific and Technical Information of China (English)

    杨锐; 太京华; 金珍婧; 潘留兰; 牟文玲

    2012-01-01

    Objective To investigate the application of combined test for serum tumor markers, I. E. Carbohydrate antigens (CA) 242 and 724, in diagnosis of pancreatic adenocarcinoma. Methods The CA242 and CA724 levels in sera of 34 patients with pancreatic adenocarcinoma, 26 patients with chronic pancreatitis and 60 healthy persons were determined by radioimmunoassay (RIA). Results The CA242 and CA724 levels in sera of patients with pancreatic adenocarcinoma at progressive stage were significantly higher than those at early stage and those of patients with chronic pancreatitis and healthy persons (each P 0. 05). The sensitivities of determination of CA242, CA724 and CA242 + CA724 in patients with pancreatic adenocarcinoma were 61. 7%, 57. 3% and 84. 9%, while the specificities were 91. 0%, 87. 6% and 90. 3%, respectively. Conclusion Quantitative determination of CA242 and CA724 were sensitive and specific for diagnosis of pancreatic adenocarcinoma, of which the sensitivity for early diagnosis was relatively low. The determination result was significantly related to the stage and prognosis of pancreatic adenocarcinoma. The sensitivity of combined test for CA242 and CA724 increased significantly, while the specificity showed no significant change.%目的 探讨血清肿瘤标志物糖类抗原(Carbohydrate antigen,CA )242(CA242)、CA724联合检测在胰腺癌诊断中的应用价值.方法 采用放射免疫法分别检测34例胰腺癌、26例慢性胰腺炎患者及60名健康体检者的血清CA242和CA724水平.结果 进展期胰腺癌组血清中CA242和CA724的水平均明显高于早期胰腺癌组、慢性胰腺炎组和正常对照组(P均<0.01),早期胰腺癌组、慢性胰腺炎组和正常对照组之间CA242和CA724的水平差异无统计学意义(P>0.05);胰腺癌患者血清中CA242、CA724单独和联合检测的敏感性分别为61.7%、57.3%和84.9%,特异性分别为91.0%、87.6%和90.3%.结论 血清肿瘤标志物CA242、CA724的定

  17. Surveillance of Diarrheagenic Escherichia coli strains isolated from diarrhea cases from children, adults and elderly at northwest of Mexico

    Directory of Open Access Journals (Sweden)

    Adrian Canizalez-Roman

    2016-11-01

    Full Text Available Diarrheagenic Escherichia coli (DEC strains are a main cause of gastrointestinal disease in developing countries. In this study we report the epidemiologic surveillance in a four-year period (January 2011 to December 2014 of DEC strains causing acute diarrhea throughout the Sinaloa State, Mexico. DEC strains were isolated from outpatients of all ages with acute diarrhea (N=1,037. Specific DEC pathotypes were identified by PCR-amplification of genes encoding virulence factors. The adhesion phenotype and antibiotic resistance were also investigated. DEC strains were detected in 23.3% (242/1037 of cases. The most frequently DEC strain isolated was EAEC (12.2%, 126/242 followed by EPEC (5.1%, 53/242, ETEC (4.3%, 43/242 DAEC (1.4%, 15/242, STEC (0.3%, 3/242 and EIEC (0.2%, 2/242. EHEC strains were not detected. Overall DEC strains were more prevalent in children ≤ 2 years of age with EPEC strains the most common of DEC pathotypes. While 65% of EAEC strains were classified as typical variant based on the aggregative adherence to in vitro cultures of HEp-2 cells, a high proportion of EPEC strains was classified as atypical strains. EAEC, EPEC, ETEC and DAEC strains were distributed in the north, central and south regions of Sinaloa state. Among all DEC strains, >90% were resistant to at least one commonly prescribed antibiotic. Strains were commonly resistant to first-line antibiotics such as tetracycline, ampicillin and sulfamethoxazole-trimethoprim. Furthermore, more than 80% of DEC isolates were multi-drug resistant and EPEC and DAEC were the categories with major proportion of this feature. In conclusion, in nearly one out of four cases of acute diarrhea in Northwestern Mexico a multi-drug resistant DEC strain was isolated, in these cases EAEC was the most prevalent (52% pathotype.

  18. Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl-2-butenal in Tg2576 Alzheimer’s disease mice model

    Directory of Open Access Journals (Sweden)

    Jin Peng

    2013-01-01

    Full Text Available Abstract Background Alzheimer’s disease (AD is pathologically characterized by excessive accumulation of amyloid-beta (Aβ fibrils within the brain and activation of astrocytes and microglial cells. In this study, we examined anti-inflammatory and anti-amyloidogenic effects of 2,4-bis(p-hydroxyphenyl-2-butenal (HPB242, an anti-inflammatory compound produced by the tyrosine-fructose Maillard reaction. Methods 12-month-old Tg2576 mice were treated with HPB242 (5 mg/kg for 1 month and then cognitive function was assessed by the Morris water maze test and passive avoidance test. In addition, western blot analysis, Gel electromobility shift assay, immunostaining, immunofluorescence staining, ELISA and enzyme activity assays were used to examine the degree of Aβ deposition in the brains of Tg2576 mice. The Morris water maze task was analyzed using two-way ANOVA with repeated measures. Otherwise were analyzed by one-way ANOVA followed by Dunnett’s post hoc test. Results Treatment of HPB242 (5 mg/kg for 1 month significantly attenuated cognitive impairments in Tg2576 transgenic mice. HPB242 also prevented amyloidogenesis in Tg2576 transgenic mice brains. This can be evidenced by Aβ accumulation, BACE1, APP and C99 expression and β-secretase activity. In addition, HPB242 suppresses the expression of inducible nitric oxide synthase (iNOS and cyclooxygenase-2 (COX-2 as well as activation of astrocytes and microglial cells. Furthermore, activation of nuclear factor-kappaB (NF-κB and signal transducer and activator of transcription 1/3 (STAT1/3 in the brain was potently inhibited by HPB242. Conclusions Thus, these results suggest that HPB242 might be useful to intervene in development or progression of neurodegeneration in AD through its anti-inflammatory and anti-amyloidogenic effects.

  19. Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors.

    Science.gov (United States)

    Ducker, G S; Atreya, C E; Simko, J P; Hom, Y K; Matli, M R; Benes, C H; Hann, B; Nakakura, E K; Bergsland, E K; Donner, D B; Settleman, J; Shokat, K M; Warren, R S

    2014-03-20

    The mammalian target of rapamycin (mTOR) regulates cell growth by integrating nutrient and growth factor signaling and is strongly implicated in cancer. But mTOR is not an oncogene, and which tumors will be resistant or sensitive to new adenosine triphosphate (ATP) competitive mTOR inhibitors now in clinical trials remains unknown. We screened a panel of over 600 human cancer cell lines to identify markers of resistance and sensitivity to the mTOR inhibitor PP242. RAS and phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) mutations were the most significant genetic markers for resistance and sensitivity to PP242, respectively; colon origin was the most significant marker for resistance based on tissue type. Among colon cancer cell lines, those with KRAS mutations were most resistant to PP242, whereas those without KRAS mutations most sensitive. Surprisingly, cell lines with co-mutation of PIK3CA and KRAS had intermediate sensitivity. Immunoblot analysis of the signaling targets downstream of mTOR revealed that the degree of cellular growth inhibition induced by PP242 was correlated with inhibition of phosphorylation of the translational repressor eIF4E-binding protein 1 (4E-BP1), but not ribosomal protein S6 (rpS6). In a tumor growth inhibition trial of PP242 in patient-derived colon cancer xenografts, resistance to PP242-induced inhibition of 4E-BP1 phosphorylation and xenograft growth was again observed in KRAS mutant tumors without PIK3CA co-mutation, compared with KRAS wild-type controls. We show that, in the absence of PIK3CA co-mutation, KRAS mutations are associated with resistance to PP242 and that this is specifically linked to changes in the level of phosphorylation of 4E-BP1.

  20. CLINICAL USE OF COMBINED DETECTION WITH TUMOR MARKERS FOR PANCREATIC CANCER

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective To explore the value of clinical use of combined detection with tumor markers for pancreatic cancer. Methods Tumor markers CA242,CA19-9 and CA50 in serum of 32 patinets with pancreatic cancer;26 patients with non-pancreatic digestive tract cancers and 24 patietns with benign pancreatic or biliary tract diseases were measured by immunoradiometric assay (IRMA). Results The levels of three markers in serum and positive rates of patients with pancreatic cancer were higher than those of other patients. The effect of measurement combining CA242 with CA19-9 was the best. The sensitivity ,specificity and accuracy of diagnosis for pancreatic cancer were 92.6%, 73.8% and 81.2% respectively. The levels of CA242 and CA19-9 were positively relative to burden of pancreatic cancer, and serum levels of these two markers of patients with resectable pancreatic cancer were lower than those with unresectable, but on difference was observed for CA50. Conclusion Combined detection of serum CA242 and CA19-9 could prove the effectual indicator for finding the patients with pancreatic cancer in high risk population or for resectable pancreatic cancer. Pre-operative measurement of serum levels of CA242 and CA19-9 is helpful to evaluate the burden of the tumors and possiblity of resect for pancreatic cancers.

  1. A dual mTORC1 and mTORC2 inhibitor shows antitumor activity in esophageal squamous cell carcinoma cells and sensitizes them to cisplatin.

    Science.gov (United States)

    Huang, Yu; Xi, Qingsong; Chen, Yu; Wang, Jing; Peng, Ping; Xia, Shu; Yu, Shiying

    2013-10-01

    The mammalian target of rapamycin (mTOR) signaling pathway is critical for the growth and proliferation of various malignant tumors, including esophageal squamous cell carcinoma (ESCC). Therefore, targeting of mTOR protein is a promising strategy for therapy in this disease. In the present study, we examined the antitumor effects of a specific mTOR kinase inhibitor, PP242, which blocks both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2) pathways, in two ESCC cell lines: Eca-109 and TE-1. We showed that PP242, but not rapamycin, attenuated the activities of both mTORC1 and mTORC2 signaling in ESCC. PP242 inhibited 4E-binding protein-1 phosphorylation and abrogated mTORC1-dependent PI3K/Akt feedback activation. Significantly, PP242 effectively suppressed ESCC cell proliferation, induced apoptosis, and arrested the cell cycle. Furthermore, PP242 promoted cisplatin-induced apoptosis and enhanced the antitumor efficacy of cisplatin in ESCC cells, which was likely to be associated with inhibition of Akt activity. Our results show that simultaneous targeting of both mTORC1 and mTORC2 pathways leads to effective antitumor actions in ESCC, and strongly suggest that dual mTORC1/2 inhibitors should be developed as potential agents for the treatment of ESCC.

  2. Genome-Wide Enzyme Annotation with Precision Control: Catalytic Families (CatFam) Databases

    Science.gov (United States)

    2008-01-01

    2.4.1.21 ( starch synthase using ADP-glucose) predicted for proteins SSG1_HORVU and SSG1_MANES are sub- sumed by EC 2.4.1.242 ( starch synthase using...glucan glucanohydrolase [Cyclodextrin glucanotransferase] SSG1_HORVUf 2.4.1.21 2.4.1.242 Starch synthase that uses either UDP- or ADP- glucose [ Starch ...exonuclease [DNA-directed DNA polymerase] MGTA_THENE 3.2.1.1 2.4.1.25 14 4-a-glucanotransferase [a- amylase ] GUX6_HUMIN 3.2.1.4 3.2.1.91 12 Exoglucanase

  3. Critical behavior of the Schwinger model with Wilson fermions

    CERN Document Server

    Azcoiti, V; Galante, A; Grillo, A F; Laliena, V

    1996-01-01

    We present a detailed analysis, in the framework of the MFA approach of the critical behaviour of the lattice Schwinger model with Wilson fermions on lattices up to 24^2, through the study of the Lee-Yang zeros and the specific heat. We find compelling evidence for a critical line ending at \\kappa = 0.25 at large \\beta. Finite size scaling analysis on lattices 8^2,12^2,16^2, 20^2 and 24^2 indicates a continuous transition. The hyperscaling relation is verified in the explored \\beta region.

  4. 氯霉素类三甲基硅衍生物的质谱特征及其残留监测

    Institute of Scientific and Technical Information of China (English)

    贺利民; 曾振灵; 刘雅红; 陈建新; 黄显会

    2004-01-01

    Mass characteristics of TMS derivative of chloramphenicol, florfenicol,and thiamphenicol were interpreted manually, respectively. Then SIM mode was performed at m/z 225, m/z 242, m/z 244, m/z 361 for CAP, m/z 178, m/z 257, m/z 259, m/z 394 for FF,and m/z 242, m/z 244, m/z 257, m/z 330 for TAP. A sensitive, reproducible gas chromatographic-mass spectrometric method was developed for simultaneous monitoring residues of fenicols in pork and tissues.

  5. GETDB: 112279 [GETDB

    Lifescience Database Archive (English)

    Full Text Available Received from the National Institute of Genetics. P/CyO;PrDr/TM3 - 2 - - 0 - cns, a small # of cells - sg - semi lethal - comment...1:A, D, comment2:42C2-C3, P on 2nd Ch (viable), lethal on 3rd Ch - - - - Show 112279 D...cns, a small # of cells Larval GFP - Larval X-gal sg Adult GFP - Lethality semi lethal Also known as - Original Comments comment...1:A, D, comment2:42C2-C3, P on 2nd Ch (viable), lethal on 3rd Ch Disc (Image) - Disc (nu

  6. Dicty_cDB: Contig-U13161-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available umber of successful extensions: 0 Number of sequences better than 10.0: 0 length of query: 115 length of dat...abase: 5,674,871 effective HSP length: 14 effective length of query: 101 effective length of database: 5,578...76 Number of successful extensions: 2 Number of sequences better than 10.0: 0 Length of query: 115 Length of... database: 95,242,211,685 Length adjustment: 22 Effective length of query: 93 Eff...s: 242 Number of sequences better than 10.0: 0 Number of HSP's gapped: 236 Number of HSP's successfully gapped: 0 Length of query

  7. Domain Modeling: NP_808907.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_808907.1 chr2 CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C A...T 2 A RESOLUTION c1a6qa_ chr2/NP_808907.1/NP_808907.1_holo_2-373.pdb blast 33R,37E,38D,60D,61G,62H,191R,242C,243D,244G,286D,287N 33R,62H,242C,286D _MN,PO4 0 ...

  8. 喉罩全麻患者在麻醉恢复室的护理

    Institute of Scientific and Technical Information of China (English)

    李蒸

    2011-01-01

    目的:PACU护士对带喉罩入室病人进行护理观察,降低并发症率,提高患者安返病房率.方法:242例病人在入室后进行机械通气,持续进行血氧饱和度,无创血压,心电,呼末二氧化碳,HR监测,用Aldrete麻醉后恢复评分法对患者进行评定.结果:242例病人均达到PACU恢复标准,安返病房.

  9. Fission cross section calculations of actinides with EMPIRE code

    Energy Technology Data Exchange (ETDEWEB)

    Sin, M.; Oblozinsky, P.; Herman,M.; Capote,R.

    2010-04-30

    The cross sections of the neutron induced reactions on {sup 233,234,236}U, {sup 237}Np, {sup 238,242}Pu, {sup 241,243}Am, {sup 242,246}Cm carried out in the energy range 1 keV-20 MeV with EMPIRE code are presented, emphasizing the fission channel. Beside a consistent, accurate set of evaluations, the paper contains arguments supporting the choice of the reaction models and input parameters. A special attention is paid to the fission parameters and their uncertainties.

  10. CCR5稳定表达的CHO细胞的构建%Construction of CHO Cells Stably Expressing CCR5

    Institute of Scientific and Technical Information of China (English)

    王芳宇; 潘忠诚

    2006-01-01

    在人体内,CCR5与许多免疫疾病有关,CCR5有望成为众多药物的作用靶点.将ccr5基因与真核表达载体pBBS242构建成重组质粒pBBS242-ccr5,转染CHO细胞,并经潮霉素B筛选.流式细胞仪检测结果表明CCR5在CHO细胞得到了稳定表达.

  11. Clinical significance of combined detection of serum levels of multiterm tumor markers in patients with upper gastrointestinal cancer%上消化道恶性肿瘤患者血清多项肿瘤标志物联合检测的临床意义

    Institute of Scientific and Technical Information of China (English)

    刘兴君; 韩存芝; 马晋峰; 张羽捷

    2009-01-01

    Objective To evaluate clinical significance of the CEA, CA19-9, CA242, AFP, CA724,SCC, TPA, TPS combined detection for the clinical diagnosis of gastrointestial cancer. Methods 373 cases of upper digestive tract malignant tumor patient and 50 cases of healthy serum sample were detected for eight markers, evaluating the relationship between the level of markers and illness. Results 8 marker diagnostic positive rates were: CEA 26.80 %, CA19-9 27.34 %, CA242 34.14 %, AFP 2.84 %, SCC 19.72 %, CA724 12.13 %, TPA 34.15 %, TPS 30.89 %. The total positive rate of joint detection of 8 markers was 89.05 %.Preoperative CEA, CA242, SCC-positive patients had a shorter survival time. CA242 and CA19-9 levels with upper gastrointestinal malignancies were positively correlated. Conclusion The combined detection of a number of markers in different pathological type and clinical staging is statistically significant, and the positive rate is much higher than any single marker test results. CA19-9 and CA242 may be the best combination of monitoring the disease. CA724, CA242 and SCC can be as adverse prognostic indicators for cardia, stomach,esophageal malignant tumors, respectively.%目的 评价痛胚抗原(CEA)、唾液酸化岩藻戊糖(CA19-9)、胃肠道癌抗原(CA242)、甲胎蛋白(AFP)、胃癌及卵巢癌抗原(CA724)、鳞状上皮细胞癌抗原(SCC)、组织多肽抗原(TPA)、细胞角蛋白(TPS)8项标志物联合检测,对上消化道恶性肿瘤的临床诊断、评价疗效及预后等方面的临床意义.方法 对373例上消化道恶性肿瘤患者及50名健康体检者血清标本进行8项标志物检测,评价标志物水平与病情的关系.结果 8项标志物诊断阳性率分别为:CEA 26.80%,CA19-9 27.34%,CA24234.14%,AFP 2.84%,SCC 19.72%,CA724 12.13%,TPA 34.15%,TPS;30.89%.8项标志物联合检查的总阳性率为89.05%.术前CEA、CA242、SCC阳性患者的生存时间较短.上消化道恶性肿瘤患者血清CA242和CA19-9水平

  12. 77 FR 6482 - Conductor Certification

    Science.gov (United States)

    2012-02-08

    ... TRANSPORTATION Federal Railroad Administration 49 CFR Part 242 Conductor Certification AGENCY: Federal Railroad..., published on November 9, 2011, which prescribed regulations for certification of conductors as required by... Certification, U.S. Department of Transportation, Federal Railroad Administration, Mail Stop-25, Room...

  13. Development of a Conditional Transgenic Mouse Model to Test the Fallopian Tube Origin of Serous Ovarian Cancer

    Science.gov (United States)

    2009-03-01

    transgene plasmid to follow up on this next strategy. KEY RESEARCH ACCOMPLISHMENTS: • molecular cloning of Ovgp1-lacZ reporter gene plasmid...high-expressing 242 line • molecular cloning of Ovgp1-Cre transgene plasmid REPORTABLE OUTCOMES: • generation of two Ovgp1-lacZ transgenic

  14. The People’s Liberation Army and China in Transition

    Science.gov (United States)

    2003-08-01

    important that China and America were allies in the war against fas- cist racism , allies in World War II. If a political opening were to occur in China...higher levels of technology on both sides. When China was selling us swizzle sticks and Barbie dolls a decade ago, technology 242 NEALER Figure 14–3

  15. Workshop: health workforce governance and integration.

    NARCIS (Netherlands)

    Batenburg, R.

    2014-01-01

    Background: Health workforce governance is increasingly recognized as a burning policy issue and focused on workforce shortages. Yet the most pressing problem is to solve maldistributions through governance and integration. Poor management of health 242 European Journal of Public Health, Vol. 24, S

  16. Occupancy Grid Map Merging Using Feature Maps

    Science.gov (United States)

    2010-11-01

    Gonzalez, “Toward a unified bayesian approach to hybrid metric-topological SLAM,” IEEE Transactions on Robotics , 24(2), April 2008, 259-270. [14] G...Risetti, C. Stachniss, and W. Burgard, “Improved Techniques for grid mapping with Rao-Blackwellized Particle Filter,” IEEE Transactions on Robotics , 23

  17. The Effectiveness of a School-Based Nutrition Intervention on Children's Fruit, Vegetables, and Dairy Product Intake

    Science.gov (United States)

    Drapeau, Vicky; Savard, Mathieu; Gallant, Annette; Nadeau, Luc; Gagnon, Jocelyn

    2016-01-01

    Background: Most Canadian children do not meet daily recommendations for consumption of vegetables and fruits (V/F) and dairy products (DP). The aim of this study was to evaluate the impact of Team Nutriathlon on V/F and DP consumption of children. Methods: Participants were 404 children from grades 5 and 6 (intervention group [IG] N = 242,…

  18. Effects of cadmium exposure on growth and metabolic profile of bermudagrass [Cynodon dactylon (L. Pers].

    Directory of Open Access Journals (Sweden)

    Yan Xie

    Full Text Available Metabolic responses to cadmium (Cd may be associated with variations in Cd tolerance in plants. The objectives of this study were to examine changes in metabolic profiles in bermudagrass in response to Cd stress and to identify predominant metabolites associated with differential Cd tolerance using gas chromatography-mass spectrometry. Two genotypes of bermudagrass with contrasting Cd tolerance were exposed to 0 and 1.5 mM CdSO4 for 14 days in hydroponics. Physiological responses to Cd were evaluated by determining turf quality, growth rate, chlorophyll content and normalized relative transpiration. All these parameters exhibited higher tolerance in WB242 than in WB144. Cd treated WB144 transported more Cd to the shoot than in WB242. The metabolite analysis of leaf polar extracts revealed 39 Cd responsive metabolites in both genotypes, mainly consisting of amino acids, organic acids, sugars, fatty acids and others. A difference in the metabolic profiles was observed between the two bermudagrass genotypes exposed to Cd stress. Seven amino acids (norvaline, glycine, proline, serine, threonine, glutamic acid and gulonic acid, four organic acids (glyceric acid, oxoglutaric acid, citric acid and malic acid, and three sugars (xylulose, galactose and talose accumulated more in WB242 than WB144. However, compared to the control, WB144 accumulated higher quantities of sugars than WB242 in the Cd regime. The differential accumulation of these metabolites could be associated with the differential Cd tolerance in bermudagrass.

  19. A mascon approach to assess ice sheet and glacier mass balances and their uncertainties from GRACE data

    NARCIS (Netherlands)

    Schrama, E.J.O.; Wouters, B.; Rietbroek, R.

    2014-01-01

    The purpose of this paper is to assess the mass changes of the Greenland Ice Sheet (GrIS), Ice Sheets over Antarctica, and Land glaciers and Ice Caps with a global mascon method that yields monthly mass variations at 10,242 mascons. Input for this method are level 2 data from the Gravity Recovery an

  20. Über einige von Edw. Jacobson auf Java gesammelte Trichopteren

    NARCIS (Netherlands)

    Ulmer, Georg

    1913-01-01

    Seit ich das letzte Verzeichniss der javanischen Triphopteren gab (Notes Leyden Mus. 32. 1910, pp. 64—66) beschrieb Cornelius Betten („Notes on the Trichoptera in the collection of the Indian Museum.” Records of the Indian Museum. Calcutta, Oct. 1909, pp. 231—242 t. 14—18) unter andern indischen Art

  1. Doing Race in Different Places: Black Racial Cohesion on Black and White College Campuses

    Science.gov (United States)

    Bentley-Edwards, Keisha L.; Chapman-Hilliard, Collette

    2015-01-01

    Understanding the range of factors that contribute to Black students' success requires scholars to examine resiliency from multifaceted perspectives that include aspects of social competency, social responsibility, and agency. Using a national sample of 242 Black college students, the current study examines the indicators that inform racial…

  2. Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples

    DEFF Research Database (Denmark)

    Jiang, Rong; Brummett, Beverly H; Hauser, Elizabeth R

    2013-01-01

    independent Caucasian samples (242 U.S. women and men; 466 Danish men) testing the hypothesis that chronic family stress also moderates the association between rs157580 and triglyceride levels. The interaction of rs157580 and family stress in predicting triglyceride levels was statistically significant...

  3. QTL Information Table: 1040 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qOE3-1 Physiological trait Eating quality overall evaluation SSR B)Fine F3 SL207 Ko...., and Imbe, T. (2007). QTL Detection for Eating Quality Including Glossiness, Stickiness, Taste and Hardness of Cooked Rice. Breeding Science 57, 231-242. ...

  4. QTL Information Table: 1042 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qTA3 Physiological trait Eating quality taste SSR B)Fine F3 SL207 Koshihikari RM133... (2007). QTL Detection for Eating Quality Including Glossiness, Stickiness, Taste and Hardness of Cooked Rice. Breeding Science 57, 231-242. ...

  5. CHARACTERIZATION AND CHROMOSOMAL ASSIGNMENT OF YEAST ARTIFICIAL CHROMOSOMES CONTAINING HUMAN 3P13-P21-SPECIFIC SEQUENCE-TAGGED SITES

    NARCIS (Netherlands)

    MICHAELIS, SC; BARDENHEUER, W; LUX, A; SCHRAMM, A; GOCKEL, A; SIEBERT, R; WILLERS, C; SCHMIDTKE, K; TODT, B; VANDERHOUT, AH; BUYS, CHCM; HEPPELLPARTON, AC; RABBITTS, PH; UNGAR, S; SMITH, D; LEPASLIER, D; COHEN, D; OPALKA, B; SCHUTTE, J

    1995-01-01

    Human chromosomal region 3p12-p23 is proposed to harbor at least three tumor suppressor genes involved in the development of lung cancer, renal cell carcinoma, and other neoplasias. In order to identify one of these genes we defined sequence tagged sites (STSs) specific for 3p13-p24.2 by analyzing a

  6. Villa HR = Villa HR

    Index Scriptorium Estoniae

    2008-01-01

    Villa (242 m2) Tallinnas teletorni lähedal. Nappi välisilmet ilmestab targasti valitud akende rütm. Arhitekt Andri Kirsima. Projektbüroo: AB Kirsima ja Niineväli. Sisearhitekt Pille Tael. Valmis: 2007. 2 plaani, 4 värv. välisvaadet, sisevaade

  7. 24 CFR 576.59 - Relocation and acquisition.

    Science.gov (United States)

    2010-04-01

    ... person is ineligible under 49 CFR 24.2(g)(2); or (D) HUD determines that the person was not displaced as...) Relocation assistance for displaced persons. A displaced person (defined in paragraph (f)(1) of this section...) Definition—(1) Displaced person. (i) The term “displaced person” means a person......

  8. 24 CFR 582.335 - Displacement, relocation, and real property acquisition.

    Science.gov (United States)

    2010-04-01

    ... CFR 24.2(g)(2); or (iv) HUD determines that the person was not displaced as a direct result of... for displaced persons. A displaced person (defined in paragraph (f) of this section) must be provided... “displaced person,” or the amount of relocation assistance for which the person is eligible, may file...

  9. 24 CFR 1003.602 - Relocation and real property acquisition.

    Science.gov (United States)

    2010-04-01

    ... person is ineligible under 49 CFR 24.2(g)(2). (iii) The grantee determines the person is not displaced as... assistance for displaced persons. A displaced person (defined in paragraph (g) of this section) must be... assistance to persons displaced by a project that is not subject to paragraph (c) of this section....

  10. 24 CFR 574.630 - Displacement, relocation and real property acquisition.

    Science.gov (United States)

    2010-04-01

    ... ineligible under 49 CFR 24.2(g)(2); or (iv) HUD determines that the person was not displaced as a direct... under this part. (b) Relocation assistance for displaced persons. A displaced person (defined in... the requirements described in 49 CFR part 24, subpart B. (d) Appeals. A person who disagrees with...

  11. 24 CFR 886.138 - Displacement, relocation, and acquisition.

    Science.gov (United States)

    2010-04-01

    ... regulations at 49 CFR part 24. A “displaced person” shall be advised of his or her rights under the Fair... person is ineligible under 49 CFR 24.2(g)(2); or (iv) HUD determines that the person was not displaced as... persons. A “displaced person” (as defined in paragraph (g) of this section) must be provided...

  12. 24 CFR 882.810 - Displacement, relocation, and acquisition.

    Science.gov (United States)

    2010-04-01

    ... CFR 24.2(g)(2); or (iv) HUD determines that the person was not displaced as a direct result of... section. (c) Relocation assistance for displaced persons. A “displaced person” (defined in paragraph (g... displaced person must be advised of his or her rights under the Fair Housing Act (42 U.S.C. 3601-19) and,...

  13. 24 CFR 891.510 - Displacement, relocation, and real property acquisition.

    Science.gov (United States)

    2010-04-01

    ....C. 4201-4655), as implemented by 49 CFR part 24. A displaced person shall be advised of his or her... under 49 CFR 24.2(g)(2); or (iv) HUD determines that the person was not displaced as a direct result of... assistance for displaced persons. A displaced person (defined in paragraph (f) of this section) must...

  14. 24 CFR 570.606 - Displacement, relocation, acquisition, and replacement of housing.

    Science.gov (United States)

    2010-04-01

    ... occupancy. (C) A person who is not displaced as described in 49 CFR 24.2(g)(2). (D) A person who the grantee... assistance for displaced persons at URA levels. (1) A displaced person shall be provided with relocation... Acquisition Policies Act of 1970 (URA) (42 U.S.C. 4601-4655). (2) Displaced person. (i) For purposes...

  15. Rethinking the Design of the Internet: The End-to-End Arguments vs. the Brave New World

    Science.gov (United States)

    2001-08-01

    the millennium.” iMP Magazine, Sept. ,http://www.cisp.org/ imp/september_99/09_99blumenthal.htm.. (67) The popular fictional character Harry Potter received...keeps its brain.” Rowling, J.K., 1998. Harry Potter and the Chamber of Secrets, Bloomsbury, p. 242. (68) Pomfret, J., 2000. “China puts clamps on

  16. 76 FR 64082 - Mandatory Reliability Standards for the Bulk-Power System; Notice of Staff Meeting

    Science.gov (United States)

    2011-10-17

    ... Energy Regulatory Commission Mandatory Reliability Standards for the Bulk-Power System; Notice of Staff...\\ Mandatory Reliability Standards for the Bulk-Power System, Order No. 693, FERC Stats. & Regs. ] 31,242... Discussion on the reliability issues relating to ``Single Point of Failure on Protection Systems,'' on...

  17. JPRS Report Science & Technology Japan STA 1988 White Paper Part 2.

    Science.gov (United States)

    1989-12-13

    crops, including potatoes and tangerines , in March 1988 at the national research institutes and JAERI. The irradiation of food has come to be...advanced technology seeds cul- tivation research consignment costs 1,253 1,242 100 Seed cultivation by advanced bio- 100 technology...Laboratory, Tsukuba Medicinal Plant Cultivation Laboratory Agricultural Research Center Agricultural Biological Resources Research Institute

  18. Students' Perceptions of the Effectiveness of the English Program Taught at the College of Technological Studies in Kuwait

    Science.gov (United States)

    Aldaihani, Hussein A.; Shuqair, Khaled M.; Alotaibi, Abdullah M.; Alrabah, Sulaiman

    2015-01-01

    This research aims at examining the Students' perceptions of the effectiveness of the English program implemented in the College of Technological Studies in Kuwait. A sample of 242 students was randomly selected from the population. The students were asked to respond to a 21-statement questionnaire designed to obtain information about how they…

  19. Proceedings of the Annual Military Librarians’ Workshop (21st): Resource Sharing, 27-29 September 1977

    Science.gov (United States)

    1977-09-29

    Library Fort Devens, MA 01433 Betty H. Fogler AV: 266-2031 Reference Librarian (Govt Docs Chief) US Air Force Academy Library SEleanor A. Driscoll USAF...Carlisle Barracks, PA 17013 Scott AFE, IL 62225 AV- 242-4442 AV: 638-3228SA 6George Vrooman Dodie C. Thomas Lihrarian Branc Offie, LndonBo 3 DevLopmerint

  20. Dicty_cDB: Contig-U14762-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 1Q.Seq.d Length = 559 Score = 712 bits (359), Expect = 0.0 Identities = 368/368 (100%) Strand = Plus / Plus Query: 183 attcan...||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 183 attcantagaaagaaatagtgcaacaatagcanaagaacaa...s = 368/368 (100%) Strand = Plus / Plus Query: 183 attcantagaaagaaatagtgcaacaatagcanaagaacaattacaaaatcaattat...taa 242 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 183 attcantagaaagaaatagtgcaacaat

  1. 45 CFR 2541.40 - Applicability.

    Science.gov (United States)

    2010-10-01

    ... 412(e) of the Immigration and Nationality Act (8 U.S.C. 1522(e)) and subsection 501(a) of the Refugee... 241-1(a), and 242 through 244 (portions of the Impact Aid program), except for 20 U.S.C....

  2. Experiment list: SRX367452 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e Diagnosis=Glioma 15549382,80.1,4.2,242 GSM1250288: LN229-control; Homo sapiens; ChIP-Seq source_name=LN229 human glioblastoma... cell line with GFP overexpression || cell line=LN229 glioblastoma cell line || genotype/

  3. Analysis Method of 241Pu Radioactivity by Isotope Dilution-Extraction Liquid Scintillation Spectrometer

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>241Pu is the only pure β emitter with the maximum energy of 20.81 keV in plutonium isotopes of 238Pu, 239Pu, 240Pu and 242Pu, in which 241Pu is mostly specific radioactivity because its half-life is 14.29 a.

  4. The Impact of Various Personal and Social Characteristics on Volunteering.

    Science.gov (United States)

    Hughes, Philip; Black, Alan

    2002-01-01

    Analysis of Australian Community Survey data (n=6,242) identified three categories of volunteer involvement: assisting those who need help, serving the wider community, and being involved in volunteer groups. Volunteers in each category had different characteristics. Key influences were having resources to contribute, existence of recruitment…

  5. Dicty_cDB: Contig-U10778-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 255 e-128 DQ980509_1( DQ980509 |pid:none) Thaumatomonas sp. TMT002 alpha tub... 242 e-128 AY818731_1( AY8187... e-122 DQ980537_1( DQ980537 |pid:none) Leucocryptos marina clone lmtua10 ... 245 e-122 EF455794_1( EF455794 |pid:none) Thaumatomo

  6. Carrier subunit of plasma membrane transporter is required for oxidative folding of its helper subunit.

    Science.gov (United States)

    Rius, Mònica; Chillarón, Josep

    2012-05-25

    We study the amino acid transport system b(0,+) as a model for folding, assembly, and early traffic of membrane protein complexes. System b(0,+) is made of two disulfide-linked membrane subunits: the carrier, b(0,+) amino acid transporter (b(0,+)AT), a polytopic protein, and the helper, related to b(0,+) amino acid transporter (rBAT), a type II glycoprotein. rBAT ectodomain mutants display folding/trafficking defects that lead to type I cystinuria. Here we show that, in the presence of b(0,+)AT, three disulfides were formed in the rBAT ectodomain. Disulfides Cys-242-Cys-273 and Cys-571-Cys-666 were essential for biogenesis. Cys-673-Cys-685 was dispensable, but the single mutants C673S, and C685S showed compromised stability and trafficking. Cys-242-Cys-273 likely was the first disulfide to form, and unpaired Cys-242 or Cys-273 disrupted oxidative folding. Strikingly, unassembled rBAT was found as an ensemble of different redox species, mainly monomeric. The ensemble did not change upon inhibition of rBAT degradation. Overall, these results indicated a b(0,+)AT-dependent oxidative folding of the rBAT ectodomain, with the initial and probably cotranslational formation of Cys-242-Cys-273, followed by the oxidation of Cys-571-Cys-666 and Cys-673-Cys-685, that was completed posttranslationally.

  7. A review of opioid prescription in a teaching hospital in Colombia [Corrigendum

    Directory of Open Access Journals (Sweden)

    Moyano J

    2015-05-01

    Full Text Available Moyano J, Figueras A. J Pain Res. 2012;5:237–242.Jairo Moyano is also affiliated with Deparment de Farmacologia, Terapeutica i Toxicologia, Universitat Autonoma de Barcelona, Barcelona, Spain, which was not included in the original publication.Read the original article

  8. Increased serum levels of fibrinogen degradation products due to treatment with recombinant tissue-type plasminogen activator for acute myocardial infarction are related to bleeding complications, but not to coronary patency

    NARCIS (Netherlands)

    R.W. Brower (Ronald); D. Collen; G.A. van Es (Gerrit Anne); J. Lubsen (Jacob); P.W.J.C. Serruys (Patrick); M.L. Simoons (Maarten); M. Verstraete (Marc); A.E.R. Arnold (Alfred)

    1989-01-01

    textabstractThe association of increasing serum levels of fibrinogen degradation products after recombinant tissue-type plasminogen activator (rt-PA) therapy with bleeding and early coronary patency was assessed in 242 patients with acute myocardial infarction. After administration of 5,000 IU hepar

  9. Civil-Military Relations: A Selected Bibliography

    Science.gov (United States)

    2011-05-01

    Relations." In Armed Forces and Society: New Challenges and Environments, edited by Centro de Estudios e Investigaciones Militares, 241-256. Santiago, Chile...CESIM [Centro de Estudios e Investigaciones Militares], June 2009. http://cronopio.flacso.cl/fondo/pub/ openaccess/2009/libro/030889.pdf#page=242

  10. Evaluation of Purine Salvage as a Chemotherapeutic Target in the Plasmodium Yoelli Rodent Model

    Science.gov (United States)

    2006-03-01

    Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA c Instituto de Medicina Molecular, Universidade de Lisboa, Av. Prof. Egas...P. berghei were not accessible at the time of ur trials. A.M. Jongco et al. / Molecular & Biochemical Parasitology 146 (2006) 242–250 249 Fig. 4

  11. Utilizing Mutual Aid in Reducing Adolescent Substance Use and Developing Group Engagement

    Science.gov (United States)

    Mogro-Wilson, Cristina; Letendre, Joan; Toi, Hiroki; Bryan, Janelle

    2015-01-01

    Objective: This study assessed the effectiveness of mutual aid groups for high school students. Methods: A quasi-experimental design was applied to 242 adolescents, where every other adolescent was assigned to the intervention or the control condition. The study evaluated the influence of implementing mutual aid groups in decreasing perceived risk…

  12. Primary School Sun Protection Policies and Practices 4 Years after Baseline--A Follow-Up Study

    Science.gov (United States)

    Reeder, Anthony I.; Jopson, Janet A.; Gray, Andrew

    2012-01-01

    Before the 2005 launch of the New Zealand SunSmart Schools Accreditation Programme (SSAP), 242 randomly sampled primary schools completed a mail survey about sun protection policies, practices, curriculum and environment. A 2009 follow-up included 189 (78%) and their mean Total Accreditation Score (TAS = total SSAP requirements met, range 0-12),…

  13. [Rapid growing liposarcoma in retroperitoneum

    DEFF Research Database (Denmark)

    Engel, L.E.; Mynster, T.

    2008-01-01

    A 36-year-old male was admitted with a giant abdominal tumour and dyspnoea from thoracic displacement. Symptoms were one year of haemorrhoids, but complaints of growing abdomen presented only for 10 weeks. Ultrasound could not differentiate tumour from the liver, but MR scan could. A 24.2 kg...

  14. Domain Modeling: NP_003809.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE p2wita_ chr20/NP_003809.1/NP_003809.1_holo_65-441.pdb swppa 130W,131Y,132F,133L,135C,152L,153V,234C,235N,236D,242F BET 0 ...

  15. Critical access hospitals enter a new era of capital finance.

    Science.gov (United States)

    Ponton, Kevin T

    2004-08-01

    One day this month, with the grand opening of Rio Grande Hospital in Del Norte, Colo., the healthcare industry will have cause to celebrate the completion of the first critical access hospital (CAH) financed with bonds enhanced by HUD FHA-242 mortgage insurance (average interest rate: 5.45%; rating: AA/Aa/AA).

  16. 48 CFR 1842.7003 - Emergency medical services and evacuation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Emergency medical services... NASA Contract Clauses 1842.7003 Emergency medical services and evacuation. The contracting officer must insert the clause at 1852.242-78, Emergency Medical Services and Evacuation, in all solicitations...

  17. [Anja Wilhelmi, Menschenbilder aus Reval und St. Peterburg. Reiseeindrücke einer Engländerin um 1840] / Paul Kaegbein

    Index Scriptorium Estoniae

    Kaegbein, Paul

    2006-01-01

    Arvustus: Anja Wilhelmi, Menschenbilder aus Reval und St. Peterburg. Reiseeindrücke einer Engländerin um 1840. In: Kollektivität und Individualität. Hamburg: Kovaè, 2001. S. 224-242. Elizabeth Rigby 1840. aastal Londonis anonüümselt ilmunud raamatust "Letters from the shores of the Baltic"

  18. Dicty_cDB: Contig-U05702-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ) Pig DNA sequence from clone CH242-256J18 on chrom... 46 2.5 1 ( EU850439 ) Adineta vaga dihydrogenpyrimid...ine dehydrogenase g... 46 2.5 1 ( EU652316 ) Adineta vaga dihydrogenpyrimidine de

  19. Dicty_cDB: Contig-U11298-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ondrial gene for sma... 48 1.5 1 ( CU466524 ) Pig DNA sequence from clone CH242-95O23 on chromo... 48 1.5 1 ( EU494534 ) Scaptodrosop...hila lebanonensis voucher 105639 16S ... 48 1.5 1 ( AC11

  20. 49 CFR Appendix A to Part 24 - Additional Information

    Science.gov (United States)

    2010-10-01

    ... workshop space. A dining area may substitute for a separate dining room. Under some circumstances, attic... person's actual out-of-pocket cost for the replacement housing.) Section 24.2(a)(8)(ii) Decent, Safe and... decent, safe, and sanitary and the tenant must be reimbursed for all reasonable out-of-pocket...

  1. Models in Insurance: Paradigms, Puzzles, Communications and Revolutions.

    Science.gov (United States)

    1980-06-01

    Models in Light of Futurism," 229-242. [80.22] A. Martinez, "Interpretaci6n del Fen6mino Actuarial mediante un Proceso Estocastico Evolutivo de Variables... Teoria della Credibilit&," Giornale dell’ Istituto degli Attuari, 27, 219-231 (1964). (D51 N. De Pril, "The Efficiency of a Bonus-Malus System," AB, 10

  2. Age 60 Study. Part 1. Bibliographic Database

    Science.gov (United States)

    1994-10-01

    States Country of Publication: Germany, Federal Republic of. 142. Dr. Ken Dychtwald, noted expert on madketing to an aging America, to address luncheon of...reserved). 242. Wilbers , Joachim (Rh#nische Friednch-Wilhelms-U Bonn Psychologisches Inst, Abteilung Etwicklungspsychologie, West Germany). Altere

  3. Quantitative geomorphology with geographical information systems (GIS) for evolving societies and science

    Science.gov (United States)

    Gomez, C.; Oguchi, T.; Evans, I. S.

    2016-05-01

    Based on the two sessions on spatial analysis, GIS and geostatistics convened by T. Oguchi, I. Evans and C. Gomez at the 2013 International Association of Geomorphology in Paris, the conveners have edited two special issues on the topic: volume 242 and the present one.

  4. Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.

    Science.gov (United States)

    Borowicz, Kinga K; Jaszczyk, Bozena; Luszczki, Jarogniew J; Czuczwar, Stanislaw J

    2007-07-12

    The aim of this study was the isobolographic evaluation of interactions between two enantiomers of losigamone, AO-242 [(+)-5(R)-alpha(S)-5-(2-chlorophenylhydroxymethyl)-4-methoxy-2(5H)-furanone] and AO-294 [(-)-5(S)-alpha(R)-5-(2-chlorophenylhydroxymethyl)-4-methoxy-2(5H)-furanone], and valproate, carbamazepine, phenytoin, or phenobarbital in the maximal electroshock test in mice. Both enantiomers interacted additively with conventional antiepileptic drugs at all studied fixed dose ratios (1:3, 1:1, 3:1). Furthermore, AO-242, AO-294 and antiepileptics applied alone, as well as combinations of enantiomers and antiepileptics did not affect motor performance in the chimney test. Significant impairment of long-term memory (passive-avoidance task) was noted only in the case of valproate alone, given at the dose equal to its median effective dose (ED(50)) against maximal electroshock. All other antiepileptics and their combinations with AO-242 or AO-294 did not impair memory of mice. Enantiomers did not affect the brain concentrations of antiepileptic drugs, indicating a pharmacodynamic nature of the observed interactions. In conclusion, the present results suggest both AO-242 and AO-294 as promising candidate drugs in the add-on therapy of refractory epilepsy.

  5. QTL Information Table: 1041 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available yashi, H., Hirayama, M., Ohta, H., Nemoto, H., Kato, H., Ando, I., Ohtsubo, K., rsquo, ichi, Yano, M., and Imbe, T. (2007). QTL Detec...tion for Eating Quality Including Glossiness, Stickiness, Taste and Hardness of Cooked Rice. Breeding Science 57, 231-242. ...

  6. QTL Information Table: 1039 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available yashi, H., Hirayama, M., Ohta, H., Nemoto, H., Kato, H., Ando, I., Ohtsubo, K., rsquo, ichi, Yano, M., and Imbe, T. (2007). QTL Detec...tion for Eating Quality Including Glossiness, Stickiness, Taste and Hardness of Cooked Rice. Breeding Science 57, 231-242. ...

  7. Dicty_cDB: Contig-U15649-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 2e-82 AB257706_1( AB257706 |pid:none) Elaphocordyceps paradoxa aldh gene... 224 3e-82 (Q56YU0) RecName: Full...ium sp. NGR234, complete g... 242 4e-80 AB257705_1( AB257705 |pid:none) Elaphocordyceps ophioglossoides al..

  8. 40 CFR 63.769 - Equipment leak standards.

    Science.gov (United States)

    2010-07-01

    ...), and paragraphs (c)(1) through (3) of this section. (7) Reciprocating compressors in wet gas service are exempt from the compressor control requirements of 40 CFR 61.242-3. (8) Flares used to comply with... defined in § 63.761; and (2) Compressors. (b) This section does not apply to ancillary equipment...

  9. Cultural Diversity in the Workplace.

    Science.gov (United States)

    Fine, Marlene G.; And Others

    1990-01-01

    Federal employees (N=242) completed 102-item questionnaire on work environment, job satisfaction, and career development. Results suggest that men, women, and people of color do not share a common organizational culture. Instead, each group defines and organizes its experience in different ways. Viewing gender and race as cultures provides a basis…

  10. InterPro search result: AK112111 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK112111 002-115-E01 IPR009059 Bipartite response regulator, C-terminal effector su...perfamily SSF46894 C-terminal effector domain of the bipartite response regulators T142-242 0.016 ...

  11. In Silico Design of Smart Binders to Anthrax PA

    Science.gov (United States)

    2012-09-01

    34GRAMM-X public web server for protein-protein docking," Nucleic Acids Research , vol. 34, pp. 310-314, 2006. [3] A. Saladin, et al., "PTools: an...Online]. [13] H. M. Berman, et al., "The Protein Data Bank," Nucleic Acids Research , vol. 28, pp. 235-242, 1999. [14] J. A. D. MacKerell, et al

  12. Enhancing our hospital with science and technology and taking people as basis

    Institute of Scientific and Technical Information of China (English)

    何忠正

    2004-01-01

    @@ The Drum Tower Hospital in Nanjing of Jiangsu Province is an ancient comprehensive hospital with a history of 112 years. It was founded in 1892 by the American-Canadian missionary W.E Macline. By the end of 1949, the hospital had owned 160 beds and had a staff of 242. It received 3667 inpatients and 78?@905 outpatients annually.

  13. 75 FR 6299 - Registration, Five-Year Terms

    Science.gov (United States)

    2010-02-09

    ... notice of proposed rulemaking in the Federal Register on December 15, 2008 (73 FR 242), seeking comment..., Packers and Stockyards Administration 9 CFR Part 201 RIN 0580-AB03 Registration, Five-Year Terms AGENCY... rule that does not establish a 5-year term for registrations. The commenter also concluded that...

  14. Harold Goldstein (R) and Dan Leiser (L) discuss bone implant development in the the Shuttle Tile

    Science.gov (United States)

    1993-01-01

    Harold Goldstein (R) and Dan Leiser (L) discuss bone implant development in the the Shuttle Tile Laboratory N-242. A spin-off of Ames research on both bone density in microgravity and on thermal protection foams is the bone-growth implant shown in 1993.

  15. VIMOS-VLT and Spitzer observations of a radio galaxy at z=2.5

    NARCIS (Netherlands)

    Villar-Martin, M; Sanchez, SF; De Breuck, C; Peletier, R; Vernet, J; Rettura, A; Seymour, N; Humphrey, A; Stern, D; Alighieri, SD; Fosbury, R

    2006-01-01

    We present: (i) a kinematic and morphological study of the giant Ly alpha nebula associated with the radio galaxy MRC 2104-242 (z = 2.49) based on integral field spectroscopic Visible Multiobject Spectrograph (VIMOS) data from the Very Large Telescope (VLT), and (ii) a photometric study of the host

  16. Small Business Innovation Research (SBIR) Program. FY 1991 Program Solicitation 91.2

    Science.gov (United States)

    1991-07-01

    lidar profilers. These one-dimensional measurements and aircraft measurements are extended to a second space dimension using the temporal evolution...production aircraft with proprotors installed in tilting engine nacelles . With its proprotors in the horizontal position, the V-22 can takeoff, hover, and...188, 218 Light Detecting and Ranging ( LIDAR ) technology. .. .. .. .. .. .. ... ... .. ... .. ... ... 240, 242 light sources

  17. 76 FR 12176 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2011-03-04

    ... establishing a definition for ``short sale price sliding,'' which is a new form of price sliding \\10\\ the... comply with Rule 201(b)(1)(i).\\12\\ Any EDGA Only Order subject to such re-pricing by the System will be... minimum pricing increments. 17 CFR 242.612. \\13\\ See Division of Trading & Markets: Responses...

  18. 76 FR 12173 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2011-03-04

    ... establishing a definition for ``short sale price sliding,'' which is a new form of price sliding \\10\\ the... comply with Rule 201(b)(1)(i).\\12\\ Any EDGX Only Order subject to such re-pricing by the System will be... minimum pricing increments. 17 CFR 242.612. \\13\\ See Division of Trading & Markets: Responses...

  19. Review of Part 67 Of the Federal Air Regulations and the Medical Certification of Civilian Airmen. Volume 2

    Science.gov (United States)

    1983-01-01

    Myocardial Disease .................................. 242 Pericardial Disease .................................. 25( Valvular Heart Disease ............................... 263...ischemic heart disease, hypertension, valvular heart disease , congenital heart disease, myocardial-pericardial disease, peripheral va3cular disease and...cardiovascular evaluation for pilots with valvular heart disease should include at a minimum echocardiogra•hy, continuous ECG monitoring and treadmill stress

  20. Genomic Basis of Prostate Cancer Health Disparity Among African-American Men

    Science.gov (United States)

    2013-07-01

    the top predictor genes, the solute carrier family SLC7A5 gene, deleted on chromosome 16q24.2, encodes a neutral aminoacid transporter protein LAT1... aminoacid concentration, L-glutamine efflux and L-leucine influx. Reduced activity of LAT1 results in increased concentrations of L-glutamine

  1. 76 FR 12645 - Ownership Limitations and Governance Requirements for Security-Based Swap Clearing Agencies...

    Science.gov (United States)

    2011-03-08

    ... COMMISSION 17 CFR Part 242 RIN 3235-AK74 Ownership Limitations and Governance Requirements for Security... FURTHER INFORMATION CONTACT: Proposals relating to security-based swap clearing agencies: Catherine Moore... in and the governance of security-based swap clearing agencies, SB SEFs and SBS...

  2. 8 CFR 241.4 - Continued detention of inadmissible, criminal, and other aliens beyond the removal period.

    Science.gov (United States)

    2010-01-01

    ... by former section 242 of the Act prior to amendment by the Illegal Immigration Reform and Immigrant... OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED... subject to the provisions of section 501(b) of the Immigration Act of 1990, Public Law 101-649, 104...

  3. Perceived Strategies and Activities for Successful Later Aging

    Science.gov (United States)

    Holahan, Carole K.; Velasquez, Katherine S.

    2011-01-01

    This study investigated perceived strategies and activities for successful later aging. Participants were 242 members of the Terman Study of the Gifted who responded to an open-ended question concerning how they make the most of their aging years. Data were collected in 1996 and 1999, when the participants were average ages of 84 and 86.…

  4. Use of quantitative real time PCR for a genome-wide study of AYWB phytoplasma gene expression in plant and insect hosts

    DEFF Research Database (Denmark)

    Makarova, Olga; MacLean, Allyson M.; Hogenhout, Saskia A.;

    2011-01-01

    this technique for reliable gene expression quantification of phytoplasmas on a large scale. In our experimental setup, 242 genes of aster yellows phytoplasma strain witches' broom (AY-WB) were tested for differences in expression in plant and insect host environments, and were shown to be predominantly...

  5. 75 FR 17027 - Nectarines and Peaches Grown in California; Changes in Handling Requirements for Fresh Nectarines...

    Science.gov (United States)

    2010-04-05

    ..., May Pearl\\TM\\, Polar Ice, Polar Light, Red Jewel or Zee Fire variety nectarines unless: * * * * * (4..., or Zee Grand variety nectarines unless: * * * * * (6) Any package or container of 15G225, 225LP242... Valley Sweet, Zee Glo or Zephyr variety nectarines unless: * * * * * PART 917--FRESH PEARS AND...

  6. Medical Entomology Studies - XIII. The Myzomyia Series of Anopheles (Cellia) in Thailand, with Emphasis on Intra-Interspecific Variations (Diptera: Culicidae) (Contributions of the American Entomological Institute. Volume 17, Number 4, 1980)

    Science.gov (United States)

    1980-01-01

    Appendix 7. The Malayan region, p. 701-12, in Russell, P. F., L. S. West, R. D. Manwell and G. Macdonald. 1963. Practical malariology. Oxford Univ. Press...Dis., Delhi. 242 p. 1963. Appendix 5. Southern and northern Asia, p. 680-96, in Russell, P. F., L. S. West, R. D. Manwell and G. MacDonald. 1963

  7. Social Identification, Perception of Aging, and Successful Aging in the Workplace

    Science.gov (United States)

    Cheung, Francis; Wu, Anise M. S.

    2014-01-01

    This study adopted self-identity theory (Tajfel & Turner, 1979) to examine the role of affective and cognitive identification and the perception of aging with regard to Chinese employees' successful aging in the workplace. A total of 242 Chinese workers in Hong Kong aged 45 and above were recruited. Results showed that cognitive identification…

  8. How Christian Spiritual and Religious Beliefs Help and Hinder Counselors' Empathy toward Clients

    Science.gov (United States)

    Morrison, Marie; Borgen, William A.

    2010-01-01

    The critical incident technique was used to examine how counselors' religion and spirituality help and hinder counselor empathy toward clients. Twelve counselors holding Christian beliefs identified 242 helping and 25 hindering incidents that formed 14 helping and 3 hindering categories. Categories reflected counselors relying on a natural…

  9. Comparison of the Effects of Various Irrigating Solutions on Dentine Permeability.

    Science.gov (United States)

    1980-09-01

    Irrigant. Oral Surg 41(20):175-177, 1980. 17. Seltzer , Samuel, and Bender , I.B. The Dental Pulp, ed. 2. Philadelphia, Lippincott, 1975, p 242. 18...microscopic study. Acta Odont Scand 30:291-311, 1972. 3. Baker, N.A.; Eleazer, P.D.; Averbach, R.E.; and Seltzer , S. Scanning electron microscopic study of

  10. Healthy lifestyle and risk of breast cancer among postmenopausal women in the European Prospective Investigation into Cancer and Nutrition cohort study

    NARCIS (Netherlands)

    McKenzie, Fiona; Ferrari, Pietro; Freisling, Heinz; Chajes, Veronique; Rinaldi, Sabina; de Batlle, Jordi; Dahm, Christina C.; Overvad, Kim; Baglietto, Laura; Dartois, Laureen; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Rosso, Stefano; Bueno-de-Mesquita, H. B(As); May, Anne; Peeters, Petra H.; Weiderpass, Elisabete; Buckland, Genevieve; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Andersson, Anne; Sund, Malin; Ericson, Ulrika; Wirfalt, Elisabet; Key, Tim J.; Travis, Ruth C.; Gunter, Marc; Riboli, Elio; Vergnaud, Anne-Claire; Romieu, Isabelle

    2015-01-01

    Breast cancer is the most common cancer among women and prevention strategies are needed to reduce incidence worldwide. A healthy lifestyle index score (HLIS) was generated to investigate the joint effect of modifiable lifestyle factors on postmenopausal breast cancer risk. The study included 242,91

  11. Predictors of Obesity Bias among Exercise Science Students

    Science.gov (United States)

    Langdon, Jody; Rukavina, Paul; Greenleaf, Christy

    2016-01-01

    The purpose of the present study was to investigate particular psychosocial predictors of obesity bias in prehealth professionals, which include the internalization of athletic and general body ideals, perceived media pressure and information, and achievement goal orientations. Exercise science undergraduate students (n = 242) filled out a survey…

  12. Production and Business Operation of Enterprises Are Improving

    Institute of Scientific and Technical Information of China (English)

    Department of Research, State Electricity Regulato; Ye Qing

    2007-01-01

    @@ Power grid operation and management In 2006,the national total revenue of power supply business amounted to 1299.242 billion Yuan,21.66%higher than that of last year:the total profits amounted to 52.035 billion Yuan;workers employed in power enterprises amounted to 1232.4 thousand.

  13. GETDB: 105361 [GETDB

    Lifescience Database Archive (English)

    Full Text Available - weak muscle cns. tr, lymph gland. distal domain in leg and antenna, internal - - comment1:A, comment...lity - Also known as - Original Comments comment1:A, comment2:42A8-A16 Disc (Image) d1 d2 d3 d4 d5 Disc (num

  14. Desiccation increases the efficacy of Beauveria bassiana for stored grain pest insects

    Science.gov (United States)

    The effect of desiccation stress on the efficacy of Beauveria bassiana for stored-product insects was investigated in laboratory bioassays. The mortality of B. bassiana-treated Plodia interpunctella larvae was greater at a vapor pressure deficit (VPD) of 2.42 kPa or 1.87 kPa than at 1.06 kPa. Moist...

  15. Walla Walla District History. Part 3. 1975-80

    Science.gov (United States)

    1980-01-01

    building dams was unques- Dams stopped floods, stored water, produced e 1 ectr i city, and created jobs. Californians built and praised multipurpose... Architecture Category in the Chief of Engineers’ Design and Environ- mental Awards Program in 1979. WEST LEWISTON LEVEE 242 Operation Fish Run

  16. Consequences for Protaphorura armata (Collembola: Onychiuridae) following exposure to genetically modified Bacillus thuringiensis (Bt) maize and non-Bt maize

    DEFF Research Database (Denmark)

    Heckmann, L.-H.; Griffiths, B. S.; Caul, S.

    2006-01-01

    armata. For comparison three non-Bt maize varieties, Rivaldo (isogenic to Cascade), Monumental (isogenic to MEB307) and DK242, and two control diets based on baker's yeast (uncontaminated and contaminated with Bt toxin Cry1Ab) were also tested. Due to a lower C:N ratio, individuals reared on yeast...

  17. 76 FR 12161 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing and Immediate...

    Science.gov (United States)

    2011-03-04

    ... short selling, including potentially manipulative or abusive short selling, from driving down further... Release, 75 FR 11232, 11247. \\28\\ See 17 CFR 242.612. With respect to NYBX pegging orders during the Short... COMMISSION Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing and...

  18. EST Table: FS744974 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS744974 E_FL_bmmt_29P20_R_0 10/09/28 73 %/242 aa ref|NP_059480.1| cytochrome c oxi...ome c oxidase subunit III [Bombyx mori] gb|ADE18474.1| cytochrome c oxidase subunit III [Bombyx mori] gb|ADE

  19. Exposure of the Distal Humerus Using a Triceps Hemi-peel Approach

    Science.gov (United States)

    2014-05-14

    approach to the elbow. Ann R Coll Surg Engl. 2010; 92:240- 242. 18. Regan WD, Korinek SL, Morrey BF, An KN. Biomechanical study of ligaments around...the elbow joint. Clin Orthop Relat Res. 1991; (271):170-179. 19. Blair JA, Stinner DJ, Kirby JM, et al. Quan- tification of femoral neck exposure

  20. An Investigation of the Relationship between Metacognition and Mathematics Achievement

    Science.gov (United States)

    Ozsoy, Gokhan

    2011-01-01

    The aim of this study is to determine fifth-grade students' metacognitive knowledge and skills and its relationship with mathematics achievements. A total of 242 primary school students from six different schools were participated in the study. Turkish version of Metacognitive Knowledge and Skills Assessment (MSA-TR) was used to measure…

  1. Operation of Algebraic Fractions

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The first step in factorizing algebraic expressions is to take out the common factors of all the terms of the expression.For example,2x~2+14x+24=2(x~2+7x+12)=2(x+3)(x+4) The three identities are also useful in factorizing some quadratic expressions:

  2. AcEST: BP915533 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 62 tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like protein OS=Zizip... 242 1e-62 ...TFMANHFDRHYCGKCGLTYVYQKA 153 >tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like protein OS=Ziziphus jujuba GN=

  3. Caries-preventive Effect of Supervised Toothbrushing and Sealants

    NARCIS (Netherlands)

    Hilgert, L.A.; Leal, S.C.; Mulder, J.; Creugers, N.H.J.; Frencken, J.E.F.M.

    2015-01-01

    To investigate the effectiveness of 3 caries-preventive measures on high- and low-caries risk occlusal surfaces of first permanent molars over 3 y. This cluster-randomized controlled clinical trial covered 242 schoolchildren, 6 to 7 y old, from low socioeconomic areas. At baseline, caries risk was a

  4. 75 FR 38980 - Certain Cased Pencils From the People's Republic of China: Final Results of the Antidumping Duty...

    Science.gov (United States)

    2010-07-07

    ...), pastels, charcoals, chalks, and pencils produced under U.S. patent number 6,217,242, from paper infused with scents by the means covered in the above-referenced patent, thereby having odors distinct from... May 28, 2010. \\1\\ ``Pencil Industry in India--A Robust Future,'' Divya Jha, in ``Paper &...

  5. The Contribution of Risk Factors to the Higher Incidence of Invasive and In Situ Breast Cancers in Women With Higher Levels of Education in the European Prospective Investigation Into Cancer and Nutrition

    NARCIS (Netherlands)

    Menvielle, Gwenn; Kunst, Anton E.; van Gils, Carla H.; Peeters, Petra H.; Boshuizen, Hendriek; Overvad, Kim; Olsen, Anja; Tjonneland, Anne; Hermann, Silke; Kaaks, Rudolf; Bergmann, Manuela M.; Illner, Anne-Kathrin; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Palli, Domenico; Berrino, Franco; Mattiello, Amelia; Tumino, Rosario; Sacerdote, Carlotta; May, Anne; Monninkhof, Evelyn; Braaten, Tonje; Lund, Eiliv; Ramon Quiros, Jose; Duell, Eric J.; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Borgquist, Signe; Manjer, Jonas; Khaw, Kay Tee; Allen, Naomi E.; Reeves, Gillian K.; Chajes, Veronique; Rinaldi, Sabina; Slimani, Nadia; Gallo, Valentina; Vineis, Paolo; Riboli, Elio; Bueno-de-Mesquita, H. Bas

    2011-01-01

    The authors investigated the role of known risk factors in educational differences in breast cancer incidence. Analyses were based on the European Prospective Investigation Into Cancer and Nutrition and included 242,095 women, 433 cases of in situ breast cancer, and 4,469 cases of invasive breast ca

  6. The contribution of risk factors to the higher incidence of invasive and in situ breast cancers in women with higher levels of education in the European prospective investigation into cancer and nutrition

    NARCIS (Netherlands)

    G. Menvielle (Gwenn); A.E. Kunst (Anton); C.H. van Gils (Carla); P.H.M. Peeters (Petra); H.C. Boshuizen (Hendriek); K. Overvad (Kim); A. Olsen (Anja); A. Tjonneland (Anne); S. Hermann (Silke); R. Kaaks (Rudolf); M.M. Bergmann (Manuela); A.-K. Illner (Anne-Kathrin); P. Lagiou (Pagona); D. Trichopoulos (Dimitrios); A. Trichopoulou (Antonia); D. Palli (Domenico); F. Berrino (Franco); A. Mattiello (Amelia); R. Tumino (Rosario); C. Sacerdote (Carlotta); A.M. May (Anne); E. Monninkhof (Evelyn); T. Braaten (Tonje); E. Lund (Eiliv); J.R. Quirós; E.J. Duell (Eric); M.J. Sánchez; C. Navarro (Carmen); S. Borgquist (Signe); J. Manjer (Jonas); K-T. Khaw (Kay-Tee); G.K. Reeves (Gillian); V. Chajes (Véronique); S. Rinaldi (Sabina); N. Slimani (Nadia); V. Gallo (Valentina); P. Vineis (Paolo); E. Riboli (Elio); H.B. Bueno-De-Mesquita (Bas); N.E. Allen (Naomi); E. Ardanaz (Eva)

    2011-01-01

    textabstractThe authors investigated the role of known risk factors in educational differences in breast cancer incidence. Analyses were based on the European Prospective Investigation Into Cancer and Nutrition and included 242,095 women, 433 cases of in situ breast cancer, and 4,469 cases of invasi

  7. Preliminary Assessment/Site Investigation: Tooele Army Depot, Utah. Volume 1. North Area and Facilities at Hill Air Force Base. Appendixes

    Science.gov (United States)

    1988-12-01

    2,4 ,6-TRINITROBENZALDENYDE ATNT kLPHA-TRINITROTOLUENE (OBSOLETE; USE 246TNT) ATZ ATRAZ1NE AYLETH ALLYL ETHER AZACN AZACYLONONANE B BORON BA BARIUM ... STYPHNATE PCB016 PCB 1016 PCB221 PCB 1221 PCB232 PCB 1232 PCB242 PCB 1242 PCB248 PCB 1248 PCB254 PCB 1254 PCB260 PCB 1260 PCB262 PCB 1262 PCP

  8. English as a Foreign Language--Teachers' Perspectives on Implementing Online Instruction in the Iranian EFL Context

    Science.gov (United States)

    Dashtestani, Reza

    2014-01-01

    This study set out to explore Iranian English as a foreign language (EFL) teachers' perceptions on the implementation of online EFL instruction. A mixed-methods design, including semi-structured interviews and questionnaires, was employed for the specific purposes of this study. A total of 242 EFL teachers participated in the questionnaire phase…

  9. Antioxidant Activity of Ecdysteroids from Serratula strangulata

    Institute of Scientific and Technical Information of China (English)

    DAI,Jing-Qiu(戴静秋); CAI,Yu-Jun(蔡育军); SHI,Yan-Ping(师彦平); ZHANG,Yong-Hong(张永红); LIU,Zhong-Li(刘中立); YANG,Li(杨立); LI,Yu(李瑜)

    2002-01-01

    One new ecdysteroid, (24R)-24-(2-hydroxyethyl)-20-hydroxyecdysone (3), as well as three known ecdysteroids, has been isolated from Chinese herb Serratula strangulata and these compounds 1-4 showed effective antioxidant activity on AAPH-induced hemolysis of human RBC and Fe2+ + cysteine-induced lipid peroxidation of liver microsome.

  10. Auxetic Metamaterials under Direct Impact Loads in a Structural Health Monitoring Framework

    Science.gov (United States)

    2013-01-01

    liquids, brittle solids (e.g., ceramics and glass), fabrics (e.g., Kevlar and nylon), composites, soils, and explosives. In addition, EPIC’s material...Applied Research 2005, 242 (3), 665–680. 10. Spadoni A. Application of Chiral Cellular Materials for the Design of Innovative Components. Ph.D

  11. 77 FR 18684 - Net Worth Standard for Accredited Investors

    Science.gov (United States)

    2012-03-28

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION 17 CFR Parts 200, 230, 240, and 242 RIN 3235-AK90 Net Worth Standard for Accredited Investors AGENCY: Securities and Exchange Commission. ACTION: Final rule; technical amendment. SUMMARY: We...

  12. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    NARCIS (Netherlands)

    Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P.; Manning, Alisa K.; Grarup, Niels; Sim, Xueling; Barnes, Daniel R.; Witkowska, Kate; Staley, James R.; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F.; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena; Mihailov, Evelin; Liu, Chunyu; Kraja, Aldi T.; Nielsen, Sune Fallgaard; Rasheed, Asif; Samue, Maria; Zhao, Wei; Bonnycastle, Lori L.; Jackson, Anne U.; Narisu, Narisu; Swift, Amy J.; Southam, Lorraine; Marten, Jonathan; Huyghe, Jeroen R.; Stancakova, Alena; Fava, Cristiano; Ohlsson, Therese; Matchan, Angela; Stirrups, Kathleen E.; Bork-Jensen, Jette; Gjesing, Anette P.; Kontto, Jukka; Perola, Markus; Shaw-Hawkins, Susan; Havulinna, Aki S.; Zhang, He; Donnelly, Louise A.; Groves, Christopher J.; Rayner, N. William; Neville, Matt J.; Robertson, Neil R.; Yiorkas, Andrianos M.; Herzig, Karl-Heinz; Kajantie, Eero; Zhang, Weihua; Willems, Sara M.; Lannfelt, Lars; Malerba, Giovanni; Soranzo, Nicole; Trabetti, Elisabetta; Verweij, Niek; Evangelou, Evangelos; Moayyeri, Alireza; Vergnaud, Anne-Claire; Nelson, Christopher P.; Poveda, Alaitz; Varga, Tibor V.; Caslake, Muriel; de Craen, Anton J. M.; Trompet, Stella; Luan, Jian'an; Scott, Robert A.; Harris, Sarah E.; Liewald, David C. M.; Marioni, Riccardo; Menni, Cristina; Farmaki, Aliki-Eleni; Hallmans, Goran; Renstrom, Frida; Huffman, Jennifer E.; Hassinen, Maija; Burgess, Stephen; Vasan, Ramachandran S.; Felix, Janine F.; Uria-Nickelsen, Maria; Malarstign, Anders; Reilly, Dermot F.; Hoek, Maarten; Vogt, Thomas F.; Lin, Honghuang; Lieb, Wolfgang; Traylor, Matthew; Markus, Hugh S.; Highland, Heather M.; Justice, Anne E.; Marouli, Eirini; Lindstrom, Jaana; Uusitupa, Matti; Komulainen, Pirjo; Lakka, Timo A.; Rauramaa, Rainer; Polasek, Ozren; Rudan, Igor; Rolandsson, Olov; Franks, Paul W.; Dedoussis, George; Spector, Timothy D.; Jousilahti, Pekka; Mannisto, Satu; Deary, Ian J.; Starr, John M.; Langenberg, Claudia; Wareham, Nick J.; Brown, Morris J.; Dominiczak, Anna F.; Connell, John M.; Jukema, J. Wouter; Sattar, Naveed; Ford, Ian; Packard, Chris J.; Esko, Tonu; Magi, Reedik; Metspalu, Andres; de Boer, Rudolf A.; van der Meer, Peter; van der Harst, Pim; Gambaro, Giovanni; Ingelsson, Erik; Lind, Lars; de Bakker, Paul I. W.; Numans, Mattijs E.; Brandslund, Ivan; Christensen, Cramer; Petersen, Eva R. B.; Korpi-Hyovalti, Eeva; Oksa, Heikki; Chambers, John C.; Kooner, Jaspal S.; Blakemore, Alexandra I. F.; Franks, Steve; Jarvelin, Marjo-Riitta; Husemoen, Lise L.; Linneberg, Allan; Skaaby, Tea; Thuesen, Betina; Karpe, Fredrik; Tuomilehto, Jaakko; Doney, Alex S. F.; Morris, Andrew D.; Palmer, Colin N. A.; Holmen, Oddgeir Lingaas; Hveem, Kristian; Willer, Cristen J.; Tuomi, Tiinamaija; Groop, Leif; Karajamaki, AnneMari; Palotie, Aarno; Ripatti, Samuli; Salomaa, Veikko; Alam, Dewan S.; Majmnder, Abdulla Al Shafi; Di Angelantonio, Emanuele; Chowdhury, Rajiv; McCarthy, Mark I.; Poulter, Neil; Stanton, Alice V.; Sever, Peter; Amouyel, Philippe; Arveiler, Dominique; Blankenberg, Stefan; Ferrieres, Jean; Kee, Frank; Kuulasmaa, Kari; Muller-Nurasyid, Martina; Veronesi, Giovanni; Virtamo, Jarmo; Deloukas, Panos; Elliott, Paul; Zeggini, Eleftheria; Kathiresan, Sekar; Melander, Olle; Kuusisto, Johanna; Laakso, Markku; Padmanabhan, Sandosh; Porteous, David J.; Hayward, Caroline; Scotland, Generation; Collins, Francis S.; Mohlke, Karen L.; Hansen, Torben; Pedersen, Oluf; Boehnke, Michael; Stringham, Heather M.; Frossard, Philippe; Newton-Cheh, Christopher; Tobin, Martin D.; Nordestgaard, Borge Gronne; Caulfield, Mark J.; Mahajan, Anubha; Morris, Andrew P.; Tomaszewski, Maciej; Samani, Nilesh J.; Saleheen, Danish; Asselbergs, Folkert W.; Lindgren, Cecilia M.; Danesh, John; Wain, Louise V.; Butterworth, Adam S.; Howson, Joanna M. M.; Munroe, Patricia B.

    2016-01-01

    High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low frequency and common genetic variants in up to 192

  13. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    NARCIS (Netherlands)

    Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P; Manning, Alisa K; Grarup, Niels; Sim, Xueling; Barnes, Daniel R; Witkowska, Kate; Staley, James R; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena; Mihailov, Evelin; Liu, Chunyu; Kraja, Aldi T; Nielsen, Sune Fallgaard; Rasheed, Asif; Samuel, Maria; Zhao, Wei; Bonnycastle, Lori L; Jackson, Anne U; Narisu, Narisu; Swift, Amy J; Southam, Lorraine; Marten, Jonathan; Huyghe, Jeroen R; Stančáková, Alena; Fava, Cristiano; Ohlsson, Therese; Matchan, Angela; Stirrups, Kathleen E; Bork-Jensen, Jette; Gjesing, Anette P; Kontto, Jukka; Perola, Markus; Shaw-Hawkins, Susan; Havulinna, Aki S; Zhang, He; Donnelly, Louise A; Groves, Christopher J; Rayner, N William; Neville, Matt J; Robertson, Neil R; Yiorkas, Andrianos M; Herzig, Karl-Heinz; Kajantie, Eero; Zhang, Weihua; Willems, Sara M; Lannfelt, Lars; Malerba, Giovanni; Soranzo, Nicole; Trabetti, Elisabetta; Verweij, Niek; Evangelou, Evangelos; Moayyeri, Alireza; Vergnaud, Anne-Claire; Nelson, Christopher P; Poveda, Alaitz; Varga, Tibor V; Caslake, Muriel; de Craen, Anton J M; Trompet, Stella; Luan, Jian'an; Scott, Robert A; Harris, Sarah E; Liewald, David C M; Marioni, Riccardo; Menni, Cristina; Farmaki, Aliki-Eleni; Hallmans, Göran; Renström, Frida; Huffman, Jennifer E; Hassinen, Maija; Burgess, Stephen; Vasan, Ramachandran S; Felix, Janine F; Uria-Nickelsen, Maria; Malarstig, Anders; Reilly, Dermot F; Hoek, Maarten; Vogt, Thomas F; Lin, Honghuang; Lieb, Wolfgang; Traylor, Matthew; Markus, Hugh S; Highland, Heather M; Justice, Anne E; Marouli, Eirini; Lindström, Jaana; Uusitupa, Matti; Komulainen, Pirjo; Lakka, Timo A; Rauramaa, Rainer; Polasek, Ozren; Rudan, Igor; Rolandsson, Olov; Franks, Paul W; Dedoussis, George; Spector, Timothy D; Jousilahti, Pekka; Männistö, Satu; Deary, Ian J; Starr, John M; Langenberg, Claudia; Wareham, Nick J; Brown, Morris J; Dominiczak, Anna F; Connell, John M; Jukema, J Wouter; Sattar, Naveed; Ford, Ian; Packard, Chris J; Esko, Tõnu; Mägi, Reedik; Metspalu, Andres; de Boer, Rudolf A; van der Meer, Peter; van der Harst, Pim; Gambaro, Giovanni; Ingelsson, Erik; Lind, Lars; de Bakker, Paul I W; Numans, Mattijs E; Brandslund, Ivan; Christensen, Cramer; Petersen, Eva R B; Korpi-Hyövälti, Eeva; Oksa, Heikki; Chambers, John C; Kooner, Jaspal S; Blakemore, Alexandra I F; Franks, Steve; Jarvelin, Marjo-Riitta; Husemoen, Lise L; Linneberg, Allan; Skaaby, Tea; Thuesen, Betina; Karpe, Fredrik; Tuomilehto, Jaakko; Doney, Alex S F; Morris, Andrew D; Palmer, Colin N A; Holmen, Oddgeir Lingaas; Hveem, Kristian; Willer, Cristen J; Tuomi, Tiinamaija; Groop, Leif; Käräjämäki, AnneMari; Palotie, Aarno; Ripatti, Samuli; Salomaa, Veikko; Alam, Dewan S; Majumder, Abdulla Al Shafi; Di Angelantonio, Emanuele; Chowdhury, Rajiv; McCarthy, Mark I; Poulter, Neil; Stanton, Alice V; Sever, Peter; Amouyel, Philippe; Arveiler, Dominique; Blankenberg, Stefan; Ferrières, Jean; Kee, Frank; Kuulasmaa, Kari; Müller-Nurasyid, Martina; Veronesi, Giovanni; Virtamo, Jarmo; Deloukas, Panos; Elliott, Paul; Zeggini, Eleftheria; Kathiresan, Sekar; Melander, Olle; Kuusisto, Johanna; Laakso, Markku; Padmanabhan, Sandosh; Porteous, David J; Hayward, Caroline; Scotland, Generation; Collins, Francis S; Mohlke, Karen L; Hansen, Torben; Pedersen, Oluf; Boehnke, Michael; Stringham, Heather M; Frossard, Philippe; Newton-Cheh, Christopher; Tobin, Martin D; Nordestgaard, Børge Grønne; Caulfield, Mark J; Mahajan, Anubha; Morris, Andrew P; Tomaszewski, Maciej; Samani, Nilesh J; Saleheen, Danish; Asselbergs, Folkert W; Lindgren, Cecilia M; Danesh, John; Wain, Louise V; Butterworth, Adam S; Howson, Joanna M M; Munroe, Patricia B

    2016-01-01

    High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to 192

  14. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    NARCIS (Netherlands)

    Surendran, P. (Praveen); F. Drenos (Fotios); R. Young (Robin); H. Warren (Helen); Cook, J.P. (James P.); A.K. Manning (Alisa); N. Grarup (Niels); X. Sim (Xueling); D. Barnes (Daniel); H.E. Witkowska (Ewa); J.R. Staley (James R.); V. Tragante (Vinicius); T. Tukiainen (Taru); H. Yaghootkar (Hanieh); Masca, N. (Nicholas); C.M. Freitag (Christine); T. Ferreira (Teresa); O. Giannakopoulou (Olga); Tinker, A. (Andrew); M. Harakalova (Magdalena); E. Mihailov (Evelin); Liu, C. (Chunyu); A. Kraja (Aldi); S.F. Nielsen (Sune); A. Rasheed (Asif); M. Samuel (Maria); W. Zhao (Wei); L.L. Bonnycastle (Lori); A.U. Jackson (Anne); N. Narisu (Narisu); A.J. Swift (Amy); L. Southam (Lorraine); J. Marten (Jonathan); J.R. Huyghe (Jeroen R.); A. Stancáková (Alena); C. Fava (Cristiano); Ohlsson, T. (Therese); A. Matchan (Angela); K. Stirrups (Kathy); J. Bork-Jensen (Jette); A.P. Gjesing (Anette); Kontto, J. (Jukka); M. Perola (Markus); S. Shaw-Hawkins (Sue); A.S. Havulinna (Aki); Zhang, H. (He); L.A. Donnelly (Louise); C.J. Groves (Christopher); N.W. Rayner (Nigel William); M.J. Neville (Matthew); N.R. Robertson (Neil); Yiorkas, A.M. (Andrianos M.); K.H. Herzig; E. Kajantie (Eero); W. Zhang (Weihua); S.M. Willems (Sara); L. Lannfelt (Lars); G. Malerba (Giovanni); N. Soranzo (Nicole); E. Trabetti (Elisabetta); N. Verweij (Niek); E. Evangelou (Evangelos); A. Moayyeri (Alireza); Vergnaud, A.-C. (Anne-Claire); C.P. Nelson (Christopher P.); Poveda, A. (Alaitz); T.V. Varga (Tibor V.); M. Caslake (Muriel); A.J.M. De Craen (Anton J. M.); S. Trompet (Stella); J. Luan (Jian'An); R.A. Scott (Robert); S.E. Harris (Sarah); D.C. Liewald (David C.); R.E. Marioni (Riccardo); C. Menni (Cristina); A.-E. Farmaki (Aliki-Eleni); G. Hallmans (Göran); F. Renström (Frida); J.E. Huffman (Jennifer); Hassinen, M. (Maija); S. Burgess (Stephen); Vasan, R.S. (Ramachandran S.); J.F. Felix (Janine); Uria-Nickelsen, M. (Maria); A. Mälarstig (Anders); Reilly, D.F. (Dermot F.); Hoek, M. (Maarten); Vogt, T.F. (Thomas F.); H. Lin (Honghuang); W. Lieb (Wolfgang); M. Traylor (Matthew); H.S. Markus (Hugh); H. Highland (Heather); A.E. Justice (Anne); E. Marouli (Eirini); J. Lindström (Jaana); M. Uusitupa (Matti); P. Komulainen (Pirjo); T.A. Lakka (Timo); R. Rauramaa (Rainer); O. Polasek (Ozren); I. Rudan (Igor); Rolandsson, O. (Olov); P.W. Franks (Paul); G.V. Dedoussis (George); T.D. Spector (Timothy); P. Jousilahti (Pekka); S. Männistö (Satu); I.J. Deary (Ian J.); J.M. Starr (John); C. Langenberg (Claudia); N.J. Wareham (Nick); M.J. Brown (Morris); A. Dominiczak (Anna); Connell, J.M. (John M.); J.W. Jukema (Jan Wouter); N. Sattar (Naveed); I. Ford (Ian); Packard, C.J. (Chris J.); T. Esko (Tõnu); R. Mägi (Reedik); A. Metspalu (Andres); R.A. de Boer (Rudolf); Van Der Meer, P. (Peter); P. van der Harst (Pim); G. Gambaro (Giovanni); Ingelsson, E. (Erik); W.H.L. Kao (Wen); P.I.W. de Bakker (Paul); M.E. Numans (Mattijs); I. Brandslund (Ivan); Christensen, C. (Cramer); Petersen, E.R.B. (Eva R. B.); E. Korpi-Hyövälti (Eeva); H. Oksa (Heikki); J.C. Chambers (John); J.S. Kooner (Jaspal S.); A.I.F. Blakemore (Alexandra); S. Franks (Steve); M.-R. Jarvelin (Marjo-Riitta); L.L.N. Husemoen (Lise Lotte); Linneberg, A. (Allan); T. Skaaby (Tea); Thuesen, B. (Betina); F. Karpe (Fredrik); J. Tuomilehto (Jaakko); A.S.F. Doney (Alex); A.D. Morris (Andrew); C.N.A. Palmer (Colin); O.L. Holmen (Oddgeir); K. Hveem (Kristian); C.J. Willer (Cristen); T. Tuomi (Tiinamaija); L. Groop (Leif); Käräjämäki, A. (Annemari); A. Palotie (Aarno); S. Ripatti (Samuli); V. Salomaa (Veikko); D.S. Alam (Dewan S.); Majumder, A.A.S. (Abdulla Al Shafi); E. di Angelantonio (Emanuele); R. Chowdhury (Rajiv); M.I. McCarthy (Mark); N.R. Poulter (Neil); A. Stanton (Alice); P. Sever (Peter); P. Amouyel (Philippe); D. Arveiler (Dominique); Blankenberg, S. (Stefan); J. Ferrieres (Jean); F. Kee (Frank); K. Kuulasmaa (Kari); M. Müller-Nurasyid (Martina); G. Veronesi (Giovanni); J. Virtamo (Jarmo); P. Deloukas (Panagiotis); P. Elliott (Paul); E. Zeggini (Eleftheria); S. Kathiresan (Sekar); O. Melander (Olle); J. Kuusisto (Johanna); M. Laakso (Markku); S. Padmanabhan (Sandosh); D. Porteous (David); C. Hayward (Caroline); G. Scotland (Generation); F.S. Collins (Francis); K.L. Mohlke (Karen); T. Hansen (T.); O. Pedersen (Oluf); M. Boehnke (Michael); H.M. Stringham (Heather); R. Frossard; C. Newton-Cheh (Christopher); M.D. Tobin (Martin); B.G. Nordestgaard (Børge); M. Caulfield (Mark); A. Mahajan (Anubha); A.P. Morris (Andrew); Tomaszewski, M. (Maciej); N.J. Samani (Nilesh); Saleheen, D. (Danish); F.W. Asselbergs (Folkert); C.M. Lindgren (Cecilia M.); J. Danesh (John); Wain, L.V. (Louise V.); A.S. Butterworth (Adam); Howson, J.M.M. (Joanna M. M.); P. Munroe (Patricia)

    2016-01-01

    textabstractHigh blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants

  15. SwissProt search result: AK240648 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK240648 J023030M24_2 (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.1.37) (RIP...-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) RIPK3_MOUSE 4e-17 ...

  16. Domain Modeling: NP_954987.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_954987.2 chr11 STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED c2phma_ chr11/NP_954987....2/NP_954987.2_holo_106-499.pdb blast 357H,358E,362H,397Y,402E,417A 196K,198S,242H,304R,307K,3

  17. Harmonic focus in thyroidectomy for substernal goiter

    DEFF Research Database (Denmark)

    Hahn, Christoffer Holst; Trolle, Waldemar; Sørensen, Christian Hjort

    2015-01-01

    , hospital stay and complications. MATERIALS AND METHODS: Prospective non-randomised study of 242 consecutive patients with substernal goiter out of 2258 patients (11%) who underwent thyroidectomy. A total of 121 patients had thyroidectomy performed with bipolar electrocoagulation and knot-tying techniques...

  18. EST Table: FS904867 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available milar to Ventricular zone-expressed PH domain-containing protein homolog 1 (Protein melted) [Acyrthosiphon p...isum] 10/09/12 48 %/242 aa FBpp0291254|melt-PC 10/08/29 32 %/245 aa K10B4.3#CE35995#WBGene00019615#status:Pa

  19. Parental Support, Depressed Affect, and Sexual Experience among Adolescents.

    Science.gov (United States)

    Whitbeck, Les B.; And Others

    1992-01-01

    Examines the effect of unsupportive family relations and low self-esteem on teenage sexual activity and alcohol use. Data from a telephone survey of 301 male and 242 female adolescents in Iowa suggested significant gender differences, with young women in unsupportive contexts seeking compensatory intimacy outside the family. (JB)

  20. 78 FR 54321 - Joint Industry Plan; Notice of Filing and Immediate Effectiveness of the Fourth Amendment to the...

    Science.gov (United States)

    2013-09-03

    ...), 75 FR 34183 (June 16, 2010) (SR-FINRA-2010-025); 62883 (September 10, 2010), 75 FR 56608 (September... be amended, is attached as Exhibit A hereto. Pursuant to Rule 608(b)(3)(iii) under Regulation NMS,\\4... (``Transmittal Letter''). \\4\\ 17 CFR 242.608(b)(3)(iii). I. Rule 608(a) of Regulation NMS A. Purpose of the...

  1. Draft Genome Sequence of Citrobacter freundii Strain A47, Resistant to the Mycotoxin Deoxynivalenol

    Science.gov (United States)

    Zhou, Ting; Lepp, Dion; Pauls, K. P.

    2017-01-01

    ABSTRACT Here, we present the draft genome sequence of Citrobacter freundii strain A47 with a length of 4,878,242 bp, which contains 4,357 putative protein coding genes, including 270 unique genes. This work is expected to assist in obtaining novel gene(s) that code for deoxynivalenol (DON) de-epoxidation enzyme(s). PMID:28302773

  2. Global Jihad: The Role of Europe’s Radical Muslims

    Science.gov (United States)

    2007-12-01

    Instituto Nacional de Estadistica , Population and Housing Census 2001, (Madrid, Spain: Instituto Nacional de Estadistica , 2001), http://www.ine.es...accessed October 2007). Instituto Nacional de Estadistica . Population and Housing Census 2001. http://www.ine.es/inebase/cgi/um?M=%2Ft20%2Fe242&O= inebase

  3. Dicty_cDB: Contig-U01814-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available one CH251-337M11 from chrom... 48 0.64 1 ( CT841554 ) Pig DNA sequence from clone CH242-267N7 on chromo... 48 0.64 1 ( AJ831604 ) Jor...danita hector mitochondrial tRNA-Leu (CUN) gen... 48 0.64 1 ( AC110798 ) Homo sapie

  4. File list: InP.Spl.10.Input_control.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Spl.10.Input_control.AllCell mm9 Input control Input control Spleen ERX662629,E...242,ERX662616,SRX701169,SRX701170,SRX701168,ERX662615,ERX662625 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Spl.10.Input_control.AllCell.bed ...

  5. Lebanon: A Convergence of Political Islam and Criminality

    Science.gov (United States)

    2012-09-01

    initiated to push the Palestinian guerrillas north of the Litani River , led to a two decade long Israeli occupation of southern Lebanon, displaced...455–475. 242 Luis Alberto Villamarin Pulido, El Cartel de las FARC, ( Bogota : Ediciones el Faraon, 1996), cited in Gregory E. Phillips, " Liberty

  6. Gclust Server: 198873 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 198873 Sto_ST1872 Cluster Sequences - 242 hypothetical protein 1 1.00e-99 0.0 0.0 0.0 0.0 3.23 0.0 Show 1988...73 Cluster ID 198873 Sequence ID Sto_ST1872 Link to cluster sequences Cluster Seque

  7. 77 FR 42625 - Modification of VOR Federal Airways V-10, V-12, and V-508 in the Vicinity of Olathe, KS

    Science.gov (United States)

    2012-07-20

    ... correction to the Napoleon, MO, radial in the V-10 and V-12 airway descriptions. This action also removes the... to the Napoleon, MO, navigation aid radial used to describe the fix's location from what was proposed in the NPRM. The corrected Napoleon, MO, radial information is changed from ``Napoleon, MO, 242...

  8. Unmanned Aerial Vehicle Mishap Taxonomy for Range Safety Reviews

    Science.gov (United States)

    2016-02-01

    either the helicopter pilot misjudged the distance as he overflew the UAV or did not see the UAV at all.  A base security officer drove onto the... Vibration ............................................................................................................ 2-15 2.4.2 Launcher-related...A-23 A.5.3 Pilot -Induced Oscillation ......................................................................................... A

  9. Half-Life Learning Curves in the Defense Acquisition Life Cycle

    Science.gov (United States)

    2012-07-01

    learning include Smith (1989); Belkaoui (1976, 1986); Nanda (1979); Pegels (1976); Richardson (1978); Towill, and Kaloo (1978); Womer (1979, 1981, 1984...analysis adjusted for learning. Management Science, 24(2), 149–160. Nanda , R. (1979). Using learning curves in integration of production resources

  10. ASASSN-15lu is a Type Ia Supernova

    OpenAIRE

    2015-01-01

    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2 UT.

  11. ASASSN-15lu is a Type Ia Supernova

    NARCIS (Netherlands)

    Leonard, D.C.; Sheehan, P.; McCarthy, D.; Follette, K.; Moustakas, J.; Cantillo, D.; Cazares-Kelly, A.; Cazares-Kelly, S.; Cendes, Y.; Damm, N.; Donati, A.; Douglas, E.; Ferrell, L.; Fosbinder-Elkins, H.; Fox, C.; Greenberg, M.; Hart, K.; Hensley, H.; Holt, A.; Hooper, E.; Juran, C.; Keane, J.; Key, K.; Korus, L.; Lee, T.; Leidig, K.; Merchak, E.; Nessmann, K.; Pendyala, S.; Pirkl, S.; Reeder, J.; Roos, A.; Rounseville, S.; Ruddy, E.; Schlingman, A.; Schlingman, W.; Schwartzman, E.; Shanmugam, V.; Silver, E.; Stein, A.; Stock, N.; Svoboda, B.; Thomas, B.; Thomas, N.; Thompson-Taylor, K.; Walton, H.

    2015-01-01

    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2

  12. The Relation of Locus of Control, Anger, and Impulsivity to Boys' Aggressive Behavior

    Science.gov (United States)

    Deming, Annie M.; Lochman, John E.

    2008-01-01

    This study attempted to discover how anger, locus of control, and impulsivity are related to aggression. Two pathways to aggression were examined: a cognitive/schema pathway and an emotion/impulsivity pathway. The sample included 242 fourth- and fifth-grade boys. Using data from several questionnaires, teachers reported on levels of reactive and…

  13. Dicty_cDB: Contig-U09823-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available aattggatttcattattgaaaatccacaaattaaatt 772 Query: 773 ccatantgcatcatatgataatttactattaaaaatcattaaacttttagaaaat...gattt 832 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 773 ccatantgcatcatatgataatttac...ttattttgttgtgatactagaaatattaaattatttttcnaacaattgg 241 Query: 742 atttcattattgaaaatccacaaattaaattccatantgcatc...atatga 790 ||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 242 atttcatta...ttgaaaatccacaaattaaattccatantgcatcatatga 290 Score = 248 bits (125), Expect(2) = 0.0 Identities = 125/125 (1

  14. Process length variation in cysts of a dinoflagellate, Lingulodinium machaerophorum, in surface sediments: investigating its potential as salinity proxy

    DEFF Research Database (Denmark)

    Mertens, Kenneth; Ribeiro, Sofia; Ilham, Bouimetarhan;

    2009-01-01

    A biometrical analysis of the dinoflagellate cyst Lingulodinium machaerophorum [Deflandre, G., Cookson, I.C., 1955. Fossil microplankton from Australia late Mesozoic and Tertiary sediments. Australian journal of Marine and Freshwater Research 6: 242–313.] Wall, 1967 in 144 globally distributed su...

  15. In Situ Optimal Reshading of Arrays with Failed Elements

    Science.gov (United States)

    2016-06-13

    1982). 2. I. Barrodale and C. Philips, 11 Solution of Overdetermined Systems of linear Equations in the Chebyshev Norm, .. Algorithm 495, ACM Trans...Equations in the l~ Norm With Constraints on the Unknowns, .. Algorithm 635, ACM Trans. on Math. Software, Vol. 11, No. 3, 242-249, (1985). 5. J. T. Lewis

  16. Law and population in Senegal : a survey of legislation

    NARCIS (Netherlands)

    Snyder, F.G.; Savané, M.-A.

    1977-01-01

    Leiden : African Studies Centre (ASC Research report, no. 5), p. 242, 1977.This preliminary survey provides, in a reference format, a compendium of legislation potentially affecting the growth, distribution and composition of thepopulation in Senegal. It starts with an introduction to the characteri

  17. 75 FR 69165 - Conductor Certification

    Science.gov (United States)

    2010-11-10

    ... From the Federal Register Online via the Government Publishing Office ] Part II Department of Transportation Federal Railroad Administration 49 CFR Part 242 Conductor Certification; Proposed Rule #0;#0;Federal Register / Vol. 75, No. 217 / Wednesday, November 10, 2010 / Proposed Rules#0;#0; ] DEPARTMENT...

  18. Effects of High Rate Shear on the Microstructure and Deformation and Fracture Behavior of Two High Strength Steels

    Science.gov (United States)

    1989-04-01

    Nickel (Ni) content between the steels. As shown in Table 1, the Q&T steel had 5% Ni while the DQ steel had only 1% Ni. Nickel in alpha iron has been...Yield and Fracture Behavior of Alpha Iron ," Trans. Met. Soc. of AIME, Vol. 242, pp. 306 - 314, February, 1968 Kalthoff, J.F. and Winkler, S., "Fracture

  19. Data of evolutionary structure change: 1DCLA-3FCTC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available C 3FCTC ALQSGNSQESVT ...1DCLA-3FCTC 1DCL 3FCT A C PSALTQ-PPSASGSLGQSVTISCTGTSSNVGGYNYVSWY...TT ure> --EEE ure> ATOM 1149 CA SER A ...e>THR CA 278 THR CA 242 3FCT...ure> EEE ure> ATOM 4447 CA ALA C 153 2.915 -50.1

  20. 77 FR 61657 - Petition for Waiver of Compliance

    Science.gov (United States)

    2012-10-10

    ... conductor certification regulations for purposes of participating in the C3RS pilot project. Amtrak, the... selected sections of 49 CFR Part 242, to encourage conductor reporting of close calls and protect conductors and Amtrak from discipline or sanctions arising from the incidents reported pursuant to...