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Sample records for california poison control

  1. Poison Control Centers

    Science.gov (United States)

    ... 1222 immediately. Name State American Association of Poison Control Centers Address AAPCC Central Office NOT A POISON ... not for emergency use. Arkansas ASPCA Animal Poison Control Center Address 1717 S. Philo Road, Suite 36 Urbana, ...

  2. Poison control center - emergency number

    Science.gov (United States)

    For a POISON EMERGENCY call: 1-800-222-1222 ANYWHERE IN THE UNITED STATES This national hotline number will let you ... is a free and confidential service. All local poison control centers in the United States use this ...

  3. 76 FR 9585 - Poison Control Program

    Science.gov (United States)

    2011-02-18

    ... HUMAN SERVICES Health Resources and Services Administration Poison Control Program AGENCY: Health... SUNY d.b.a. the Upstate New York Poison Control Center. HRSA will also transfer funds and duties from Winthrop University to the New York City Health & Hospitals Corporation d.b.a. the New York City...

  4. Poison control center - Emergency number (image)

    Science.gov (United States)

    For a poison emergency call 1-800-222-1222 anywhere in the United States. This national hotline number will let you ... is a free and confidential service. All local poison control centers in the U.S. use this national ...

  5. The Poison Control Center--Its Role

    Science.gov (United States)

    Manoguerra, Anthony S.

    1976-01-01

    Poison Control Centers are being utilized by more schools of pharmacy each year as training sites for students. This paper discusses what such a center is, its services, changes anticipated in the poison center system in the next several years and how they may influence pharmacy education, specifically as it relates to clinical toxicology.…

  6. American Association of Poison Control Centers

    Science.gov (United States)

    ... National Poison Data System Our Work Alerts Keep Up-to-Date on the Latest Poison News The AAPCC works ... the latest poison safety and prevention news! Sign Up! Save the Date! Medication Safety 101 Twitter Chat Medication Safety 101: ...

  7. Pick your poison: what's new in poison control for the preschooler.

    Science.gov (United States)

    Glenn, Lauren

    2015-01-01

    Accidental childhood poisonings are a major public health concern despite many efforts to alleviate this problem. While the rate of pediatric fatalities due to poisonings have decreased over the last two decades, poison control centers around the US have collectively fielded over one million calls with regard to toxic exposures in the preschool age group. According to the American Association of Poison Control Centers nearly half of all human exposures reported last year involved children under six. By focusing poison prevention efforts on the preschooler, we can attempt to decrease morbidity and mortality in the most vulnerable age group affected. Although the subject is still prevalent, current discussion on this topic is limited. Newer literature discusses past initiatives such as child resistant packaging and sticker deterrent programs and addresses their efficacy. This article revisits older mechanisms of prevention as well as the science behind the human motivation to change one's own practice and behavior.

  8. Retrospective study of cattle poisonings in California: recognition, diagnosis, and treatment

    Directory of Open Access Journals (Sweden)

    Puschner B

    2012-11-01

    Full Text Available Anita Varga,1 Birgit Puschner21William R Pritchard Veterinary Medical Teaching Hospital, Large Animal Clinic, School of Veterinary Medicine, University of California, Davis, CA, USA; 2Department of Molecular Biosciences and the California Animal Health and Food Safety Laboratory System, School of Veterinary Medicine, University of California, Davis, CA, USAAbstract: In this retrospective study all suspect bovine intoxications submitted to the California Animal Health and Food Safety Laboratory between January 1, 2000 and December 31, 2011 were reviewed. A total of 1199 cases were submitted, but a diagnosis of intoxication was only established in 13.5% of cases. In these cases, overexposures to minerals, metals, and poisonous plants were determined as the most commonly diagnosed poisonings in cattle in California. Nitrate/nitrite poisoning was the most commonly diagnosed plant-associated intoxication, followed by gossypol and oleander. This study details the diagnostic challenges and treatment options for the most commonly diagnosed intoxications. To ensure proper treatment and prevention of new cases, accurate diagnosis is necessary, and therefore this review provides an essential tool for the food animal practitioner. Available toxicological analyses are offered at select laboratories, which can be time consuming and expensive, yet the potential for residues in consumed animal products and implications for human health necessitate testing and consultation. Any potential exposure to a toxicant in cattle should be reviewed to determine whether a residue hazard exists. Therapy focuses on immediate removal of the toxicant from the environment and from the gastrointestinal tract. With few antidotes available, most are cost prohibitive to treat numerous affected cattle. In addition, most antidotes will require extra-label drug use and establishment of meat and milk withdrawal times.Keywords: toxins, toxicology, poisonous plants, bovine

  9. Poisoning

    Science.gov (United States)

    ... team will provide additional treatment. They can use methods to get rid of the poison before it causes more harm. Some types of poison have antidotes. These work by reversing the poison’s effects and curing it. Treatment also includes measures to relieve symptoms. ...

  10. Unintentional carbon monoxide poisoning hospitalization and emergency department counts and rates by county, year, and fire-relatedness among California residents,2000-2007

    Data.gov (United States)

    California Environmental Health Tracking Program — This dataset contains case counts, rates, and confidence intervals of unintentional carbon monoxide poisoning (CO) inpatient hospitalizations and emergency...

  11. Childhood lead poisoning data for California by county, age, and blood lead level for the years 2007-2009; and age of housing data for 2000.

    Data.gov (United States)

    California Environmental Health Tracking Program — This dataset contains counts and percentages of blood lead levels among children tested for lead poisoning during 2007-2009 within California . The data are...

  12. Update: mercury poisoning associated with beauty cream--Arizona, California, New Mexico, and Texas, 1996.

    Science.gov (United States)

    1996-07-26

    During September 1995-May 1996, the Texas Department of Health (TDH), the New Mexico Department of Health (NMDH), and the San Diego County (California) Health Department investigated three cases of mercury poisoning associated with the use of a mercury-containing beauty cream produced in Mexico. The ongoing investigation has found this product in shops and flea markets in the United States located near the U.S.-Mexico border, and a U.S. distributor has been identified in Los Angeles. The cream, marketed as "Crema de Belleza--Manning" for skin cleansing and prevention of acne, listed "calomel" (mercurous chloride [Hg2Cl2]) as an ingredient and contained 6% to 10% mercury by weight. This report presents findings of a continuing investigation by these health departments, the Arizona Dept of Health Services (ADHS), California State Department of Health Services (CSDHS), the Food and Drug Administration (FDA), and CDC.

  13. Deodorant poisoning

    Science.gov (United States)

    ... if known) Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  14. Jimsonweed poisoning

    Science.gov (United States)

    ... if known Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  15. Detergent poisoning

    Science.gov (United States)

    ... if known) Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  16. Foxglove poisoning

    Science.gov (United States)

    ... if known Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  17. Nicotine poisoning

    Science.gov (United States)

    ... help if this information is not immediately available. Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  18. Mistletoe poisoning

    Science.gov (United States)

    ... if known Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  19. Bee poison

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/002847.htm Bee poison To use the sharing features on this page, ... of insect, if possible Time of the sting Poison Control Your local poison center can be reached ...

  20. Gasoline poisoning

    Science.gov (United States)

    ... condition Time the gasoline was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  1. Philodendron poisoning

    Science.gov (United States)

    ... if known Time it was swallowed Amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  2. Surveillance of poisoning and drug overdose through hospital discharge coding, poison control center reporting, and the Drug Abuse Warning Network.

    Science.gov (United States)

    Blanc, P D; Jones, M R; Olson, K R

    1993-01-01

    There is no gold standard for determining poisoning incidence. We wished to compare four measures of poisoning incidence: International Classification of Diseases 9th Revision (ICD-9) principal (N-code) and supplemental external cause of injury (E-code) designations, poison control center (PCC) reporting, and detection by the Drug Abuse Warning Network (DAWN). We studied a case series at two urban hospitals. We assigned ICD-9 N-code and E-code classifications, determining whether these matched with medical records. We ascertained PCC and DAWN system reporting. A total of 724 subjects met entry criteria; 533 were studied (74%). We matched poisoning N-codes for 278 patients (52%), E-code by cause in 306 patients (57%), and E-code by intent in 171 patients (32%). A total of 383 patients (72%) received any poisoning N-code or any E-code. We found that PCC and DAWN reporting occurred for 123 of all patients (23%) and 399 of 487 eligible patients (82%), respectively. In multiple logistic regression, factors of age, hospital admission, suicidal intent, principal poisoning or overdose type, and mixed drug overdose were statistically significant predictors of case match or report varying by surveillance measure. Our findings indicate that common surveillance measures of poisoning and drug overdose may systematically undercount morbidity.

  3. Evaluation of completeness of selected poison control center data fields.

    Science.gov (United States)

    Jaramillo, Jeanie E; Marchbanks, Brenda; Willis, Branch; Forrester, Mathias B

    2010-08-01

    Poison control center data are used in research and surveillance. Due to the large volume of information, these efforts are dependent on data being recorded in machine readable format. However, poison center records include non-machine readable text fields and machine readable coded fields, some of which are duplicative. Duplicating this data increases the chance of inaccurate/incomplete coding. For surveillance efforts to be effective, coding should be complete and accurate. Investigators identified a convenience sample of 964 records and reviewed the substance code determining if it matched its text field. They also reviewed the coded clinical effects and treatments determining if they matched the notes text field. The substance code matched its text field for 91.4% of the substances. The clinical effects and treatments codes matched their text field for 72.6% and 82.4% of occurrences respectively. This under-reporting of clinical effects and treatments has surveillance and public health implications.

  4. NWHL final report 1984 [ to ] 1985 lead poisoning monitoring program Modoc National Wildlife Refuge California

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Twelve carcasses were submitted for necropsy from Modoc National Wildlife Refuge (NWR) during the 1984-85 Lead Poisoning Monitoring Program; one Canada goose was...

  5. Poison ivy - oak - sumac

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/002886.htm Poison ivy - oak - sumac To use the sharing features ... the plant, if known Amount swallowed (if swallowed) Poison Control Your local poison center can be reached ...

  6. Poisoning - fish and shellfish

    Science.gov (United States)

    ... help if this information is not immediately available. Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  7. Nail polish poisoning

    Science.gov (United States)

    ... The time it was swallowed The amount swallowed Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  8. Bug spray poisoning

    Science.gov (United States)

    ... was swallowed or inhaled Amount swallowed or inhaled Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere ...

  9. Effects of a major earthquake on calls to regional poison control centers.

    Science.gov (United States)

    Nathan, A R; Olson, K R; Everson, G W; Kearney, T E; Blanc, P D

    1992-03-01

    We retrospectively evaluated the effect of the Loma Prieta earthquake on calls to 2 designated regional poison control centers (San Francisco and Santa Clara) in the area. In the immediate 12 hours after the earthquake, there was an initial drop (31%) in call volume, related to telephone system overload and other technical problems. Calls from Bay Area counties outside of San Francisco and Santa Clara decreased more dramatically than those from within the host counties where the poison control centers are located. In the next 2 days, each poison control center then handled a 27% increase in call volume. Requests for information regarding safety of water supplies and other environmental concerns were significantly increased. The number of cases of actual poisoning exposure decreased, particularly poison and drug ingestions in children. Most calls directly related to the earthquake included spills and leaks of hazardous materials and questions about water and food safety. Regional poison control centers play an essential role in the emergency medical response to major disasters and are critically dependent on an operational telephone system.

  10. A CASE CONTROL STUDY OF INTRAVENOUS MAGNESIUM SULPHATE IN TREATMENT OF ACUTE ORGANOPHOSPHATE POISONING

    Directory of Open Access Journals (Sweden)

    James

    2016-05-01

    Full Text Available BACKGROUND To study the efficacy of intravenous magnesium sulphate in the treatment of OPC poisoning and its outcome. To assess merits and demerits of use of MgSO4 with conventional therapy. METHOD This is a case control study of patients admitted with severe OPC poisoning in intensive care medical unit of tertiary care hospital. RESULTS Total of 69 cases and 64 control patients were compared. Among both cases and controls incidence of poisoning was more common among male sex and common among patients belonging to third decade of age. When compared to control arm, there is statistically significant reduction in mortality when intravenous MgSO4 was given to patients in addition to standard treatment protocol for severe OPC poisoning. CONCLUSION In our study, addition of MgSO4 has shown significant clinical improvement of severe OPC poisoning with no adverse outcome. Long term and large studies are needed to determine the efficacy of MgSO4 in treatment of OPC poisoning

  11. Effects of a major earthquake on calls to regional poison control centers.

    OpenAIRE

    Nathan, A. R.; Olson, K.R.; Everson, G. W.; Kearney, T E; Blanc, P. D.

    1992-01-01

    We retrospectively evaluated the effect of the Loma Prieta earthquake on calls to 2 designated regional poison control centers (San Francisco and Santa Clara) in the area. In the immediate 12 hours after the earthquake, there was an initial drop (31%) in call volume, related to telephone system overload and other technical problems. Calls from Bay Area counties outside of San Francisco and Santa Clara decreased more dramatically than those from within the host counties where the poison contro...

  12. Malathion poisoning

    Science.gov (United States)

    ... local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) ... to kill and control insects on crops and in gardens. The government also uses it to kill mosquitoes in large ...

  13. Damage and Control of Poisonous Weeds in Western Grassland of China

    Institute of Scientific and Technical Information of China (English)

    ZHAO Bao-yu; SHI Zhi-cheng; LIU Zhong-yan; LU Hao; WANG Zhan-xin; SUN Li-sha; WAN Xue-pan; GUO Xi; ZHAO Yan-tao; WANG Jian-jun

    2010-01-01

    Western grassland is the main source of living and means of production of western inhabitants. For many years,desertification and poisonous-weeds growth in grassland were resulted from over-grazing, over-reclaiming, over-spading and population growth. Western natural ecological environment is destroyed severly. Meanwhile, it has restricted the sustainable development of animal husbandry. The fast spreading poisonous-weeds, which caused grassland ecology unbalance, is one of the considerable bioecology problems and an important index of grassland degeneration. Based on analysis and induction of previous data, this article introduced the situation of poisonous-weeds disaster of western grassland in recent decades, category and distribution of poisonous-weeds, integrated control and reasonable utilization.

  14. Mercury poisoning associated with beauty cream--Texas, New Mexico, and California, 1995-1996.

    Science.gov (United States)

    1996-05-17

    The Texas Department of Health (TDH), New Mexico Department of Health (NMDH), and San Diego County Health Department (SDCHD) recently investigated three cases of mercury poisoning among persons who had used a beauty cream produced in Mexico. The investigations implicated the beauty cream as the source of the mercury. The cream, marketed as "Crema de Belleza--Manning," lists "calomel" (mercurous chloride) as an ingredient and was found to contain 6%-8% mercury by weight. This report summarizes the ongoing investigation of these and other possible cases.

  15. 75 FR 11878 - California State Motor Vehicle Pollution Control Standards; Amendments to the California Zero...

    Science.gov (United States)

    2010-03-12

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Amendments to the California Zero... certification, inspection or any other approval relating to the control of emissions from any new motor vehicle... standards) for the control of emissions from new motor vehicles or new motor vehicle engines prior to...

  16. 76 FR 70128 - California State Motor Vehicle Pollution Control Standards; Amendments to the California Heavy...

    Science.gov (United States)

    2011-11-10

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Amendments to the California Heavy... thereof shall adopt or attempt to enforce any standard relating to the control of emissions from new motor..., inspection or any other approval relating to the control of emissions from any new motor vehicle or new...

  17. The Current State of Poison Control Centers in Pakistan and the Need for Capacity Building

    Directory of Open Access Journals (Sweden)

    Nadeem Khan

    2014-03-01

    Full Text Available Background: Chemical exposure is a major health problem globally. Poison control centers (PCCs play a leading role both in developed and developing countries in the prevention and control of poisonous chemical exposures. In this study, we aimed to assess the current state of PCCs in Pakistan and highlight capacity building needs in these centers. Methods: A cross-sectional survey of the two registered PCCs was done during August – December 2011. Necessary services of the PCCs were evaluated and the data were recorded on a predesigned checklist. Results: Both PCCs are affiliated to a tertiary care hospital. Clinical services to poisoned patients were available 24 hours a day / 7 days a week. Information on common local products was available to poison center staff. Both centers were involved in undergraduate and post graduate teaching. Telephone poison information service was not available in either of centers. There was a limited capacity for qualitative and analytical toxicology. Common antidotes were available. There were limited surveillance activities to capture toxic risks existing in the community and also a deficiency was observed in chemical disaster planning. Conclusion: PCCs in Pakistan need capacity building for specialized training in toxicology, toxicovigilance, chemical disaster planning, analytical laboratory tests and telephone service for consultation in poisoning cases.   How to cite this article: Khan NU, Mir MU, Khan UR, Khan AR, Ara J, Raja K, et al. The Current State of Poison Control Centers in Pakistan and the Need for Capacity Building. Asia Pac J Med Toxicol 2014;3:31-5.

  18. Prevention of Food Poisoning.

    Science.gov (United States)

    Army Quartermaster School, Ft. Lee, VA.

    The programed text provides a single lesson, four-hour, correspondence subcourse on the prevention of food poisoning. It covers the following areas: a definition of food poisoning; chemical food poisoning; biological food poisoning; causes and prevention of trichinosis; six factors controlling bacteria growth; bacterial infection; prevention of…

  19. Histamine poisoning and control measures in fish and fishery products

    Directory of Open Access Journals (Sweden)

    Pierina eVisciano

    2014-09-01

    Full Text Available Histamine poisoning is one of the most common form of intoxication caused by the ingestion of fish and fishery products. Cooking, canning or freezing cannot reduce the levels of histamine because this compound is heat stable. All humans are susceptible to histamine and its effects can be described as intolerance or intoxication depending on the severity of the symptoms. The amount of histamine in food, the individual sensitivity and the detoxification activity in human organism represent the main factors affecting the toxicological response in consumers. Histamine is the only biogenic amine with regulatory limits set by European Legislation, up to a maximum of 200 mg/kg in fresh fish and 400 mg/kg in fishery products treated by enzyme maturation in brine.

  20. Gastric Lavage in Acute Organophosphorus Pesticide poisoning (GLAOP – a randomised controlled trial of multiple vs. single gastric lavage in unselected acute organophosphorus pesticide poisoning

    Directory of Open Access Journals (Sweden)

    Cao YuPing

    2006-10-01

    Full Text Available Abstract Background Organophosphorus (OP pesticide poisoning is the most common form of pesticide poisoning in many Asian countries. Guidelines in western countries for management of poisoning indicate that gastric lavage should be performed only if two criteria are met: within one hour of poison ingestion and substantial ingested amount. But the evidence on which these guidelines are based is from medicine overdoses in developed countries and may be irrelevant to OP poisoning in Asia. Chinese clinical experience suggests that OP remains in the stomach for several hours or even days after ingestion. Thus, there may be reasons for doing single or multiple gastric lavages for OP poisoning. There have been no randomised controlled trials (RCTs to assess this practice of multiple lavages. Since it is currently standard therapy in China, we cannot perform a RCT of no lavage vs. a single lavage vs. multiple lavages. We will compare a single gastric lavage with three gastric lavages as the first stage to assess the role of gastric lavage in OP poisoning. Methods/Design We have designed an RCT assessing the effectiveness of multiple gastric lavages in adult OP self-poisoning patients admitted to three Chinese hospitals within 12 hrs of ingestion. Patients will be randomised to standard treatment plus either a single gastric lavage on admission or three gastric lavages at four hour intervals. The primary outcome is in-hospital mortality. Analysis will be on an intention-to-treat basis. On the basis of the historical incidence of OP at the study sites, we expect to enroll 908 patients over three years. This projected sample size provides sufficient power to evaluate the death rate; and a variety of other exposure and outcome variables, including particular OPs and ingestion time. Changes of OP level will be analyzed in order to provide some toxic kinetic data. Discussion the GLAOP study is a novel, prospective cohort study that will explore to the toxic

  1. Food Poisoning

    Science.gov (United States)

    ... de los dientes Video: Getting an X-ray Food Poisoning KidsHealth > For Kids > Food Poisoning Print A ... find out how to avoid it. What Is Food Poisoning? Food poisoning comes from eating foods that ...

  2. Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Michael Eddleston

    2009-06-01

    Full Text Available BACKGROUND: Poisoning with organophosphorus (OP insecticides is a major global public health problem, causing an estimated 200,000 deaths each year. Although the World Health Organization recommends use of pralidoxime, this antidote's effectiveness remains unclear. We aimed to determine whether the addition of pralidoxime chloride to atropine and supportive care offers benefit. METHODS AND FINDINGS: We performed a double-blind randomised placebo-controlled trial of pralidoxime chloride (2 g loading dose over 20 min, followed by a constant infusion of 0.5 g/h for up to 7 d versus saline in patients with organophosphorus insecticide self-poisoning. Mortality was the primary outcome; secondary outcomes included intubation, duration of intubation, and time to death. We measured baseline markers of exposure and pharmacodynamic markers of response to aid interpretation of clinical outcomes. Two hundred thirty-five patients were randomised to receive pralidoxime (121 or saline placebo (114. Pralidoxime produced substantial and moderate red cell acetylcholinesterase reactivation in patients poisoned by diethyl and dimethyl compounds, respectively. Mortality was nonsignificantly higher in patients receiving pralidoxime: 30/121 (24.8% receiving pralidoxime died, compared with 18/114 (15.8% receiving placebo (adjusted hazard ratio [HR] 1.69, 95% confidence interval [CI] 0.88-3.26, p = 0.12. Incorporating the baseline amount of acetylcholinesterase already aged and plasma OP concentration into the analysis increased the HR for patients receiving pralidoxime compared to placebo, further decreasing the likelihood that pralidoxime is beneficial. The need for intubation was similar in both groups (pralidoxime 26/121 [21.5%], placebo 24/114 [21.1%], adjusted HR 1.27 [95% CI 0.71-2.29]. To reduce confounding due to ingestion of different insecticides, we further analysed patients with confirmed chlorpyrifos or dimethoate poisoning alone, finding no evidence of

  3. Treatment of Severe Poison Ivy: A Randomized, Controlled Trial of Long Versus Short Course Oral Prednisone

    OpenAIRE

    2014-01-01

    Background Toxidendron (poison ivy, oak, and sumac) contact dermatitis is a common complaint in the outpatient primary care setting with little evidence-based guidance on best treatment duration. Methods This randomized, controlled trial examined the efficacy and side effects of a 5-day regimen of 40 mg oral prednisone daily (short course) compared to the same 5-day regimen followed by a prednisone taper of 30 mg daily for 2 days, 20 mg daily for 2 days, 10 mg daily for 2 days, and 5 mg daily...

  4. 75 FR 70237 - California State Motor Vehicle Pollution Control Standards; California Heavy-Duty On-Highway Otto...

    Science.gov (United States)

    2010-11-17

    ... AGENCY California State Motor Vehicle Pollution Control Standards; California Heavy-Duty On-Highway Otto... thereof shall adopt or attempt to enforce any standard relating to the control of emissions from new motor..., inspection or any other approval relating to the control of emissions from any new motor vehicle or new...

  5. Poison Ivy

    Science.gov (United States)

    ... Emergency Room? What Happens in the Operating Room? Poison Ivy KidsHealth > For Kids > Poison Ivy Print A ... the leaves of the plants. Look Out for Poison Plants These plants can be anywhere — from the ...

  6. 77 FR 64997 - Advisory Committee on Childhood Lead Poisoning Prevention

    Science.gov (United States)

    2012-10-24

    ... HUMAN SERVICES Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning... poisoning prevention efforts. The committee also reviews and reports regularly on childhood lead poisoning prevention practices and recommends improvements in national childhood lead poisoning prevention...

  7. 75 FR 45082 - Revisions to the California State Implementation Plan, Santa Barbara County Air Pollution Control...

    Science.gov (United States)

    2010-08-02

    ... Air Pollution Control District (SBCAPCD) portion of the California State Implementation Plan (SIP... Environmental protection, Air pollution control, Intergovernmental relations, Nitrogen dioxide, Ozone, Reporting... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Santa Barbara County...

  8. 10 "Poison Pills" for Pets

    Science.gov (United States)

    ... Care Animal Welfare Veterinary Careers Public Health 10 "Poison Pills" for Pets Anyone who takes medication prescribed ... of all phone calls to the ASPCA Animal Poison Control Center (APCC) are about human medications. Your ...

  9. A Retrospective Review of the Presentation and Treatment of Stingray Stings Reported to a Poison Control System.

    Science.gov (United States)

    Clark, Alexander T; Clark, Richard F; Cantrell, F Lee

    We studied stingray stings reported to our poison system to identify associated complications and treatments. We undertook a 14-year retrospective observational analysis of stingray stings reported to our poison system. Extracted data included caller age and gender, outcome, management site, symptoms, treatments, and geographical location of the sting. We examined suspected infection rate, hot water treatment efficacy, and possible presence of foreign bodies in the wound. Suspected infection rate was defined as "possible infection" or "likely infection." Hot water treatment efficacy was defined as cases that encoded hot water as a treatment and noted pain relief within 1 hour of treatment in the free-text record, before documentation of other analgesic administration. A total of 576 envenomations were reported. The majority were men (76%), with an average age of 24 years (range, 6-78 years). Symptoms were reported in 485 cases. A total of 9% recorded a foreign body or debris at the wound site. Symptoms included pain (79%), puncture wound (65%), and edema (25%). Infections were reported in 9% of cases. Hot/warm water immersion appeared effective for pain relief in 69% of cases where outcome was documented. The most common geographical location of stingray envenomations was Southern California. Stingray stings are common in California. Hot/warm water seemed to be effective in pain management in our series, whereas foreign bodies or retained spines and infections were other identified complications.

  10. [Electronic poison information management system].

    Science.gov (United States)

    Kabata, Piotr; Waldman, Wojciech; Kaletha, Krystian; Sein Anand, Jacek

    2013-01-01

    We describe deployment of electronic toxicological information database in poison control center of Pomeranian Center of Toxicology. System was based on Google Apps technology, by Google Inc., using electronic, web-based forms and data tables. During first 6 months from system deployment, we used it to archive 1471 poisoning cases, prepare monthly poisoning reports and facilitate statistical analysis of data. Electronic database usage made Poison Center work much easier.

  11. Dual control of low concentration CO poisoning by anode air bleeding of low temperature polymer electrolyte membrane fuel cells

    Science.gov (United States)

    Klages, Merle; Tjønnås, Johannes; Zenith, Federico; Halvorsen, Ivar J.; Scholta, Joachim

    2016-12-01

    Fuel impurities, fed to a polymer electrolyte membrane fuel cell, can affect stack performance by poisoning of catalyst layers. This paper describes the dynamic behaviour of a stack, including state-of-the-art membrane electrode assemblies (MEA) of three different manufacturers, at different operating conditions. The voltage transients of the step responses to CO poisoning as well as air bleed recovery are compared, revealing differences in performance loss: slow poisoning versus fast recovery, incomplete recovery and voltage oscillation. The recorded behaviour is used to develop a model, based on Tafel equation and first order dynamic response, which can be calibrated to each MEA type. Using this model to predict voltage response, a controller is built with the aim of reducing the total amount of air bleed and monitoring upstream stack processes without the need of sensors measuring the poisoning level. Two controllers are implemented in order to show the concept from a heuristic, easy to implement, and a more technical side allowing more detailed analysis of the synthesis. The heuristic algorithm, based on periodic perturbations of the manipulated variable (air-bleed), is validated on a real stack, revealing a stabilized performance without the need of detailed stack properties knowledge.

  12. Outsmarting Poison Ivy and Other Poisonous Plants

    Science.gov (United States)

    ... For Consumers Home For Consumers Consumer Updates Outsmarting Poison Ivy and Other Poisonous Plants Share Tweet Linkedin ... tips to avoid it. back to top Recognizing Poison Ivy, Poison Oak, and Poison Sumac Open PDF ...

  13. Starch poisoning

    Science.gov (United States)

    Cooking starch poisoning; Laundry starch poisoning ... Cooking and laundry starch are both made from vegetable products, most commonly: Corn Potatoes Rice Wheat Both are usually considered nonpoisonous (nontoxic), but ...

  14. Insecticide poisoning

    Science.gov (United States)

    ... Poisoning and Drug Overdose . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 76. Borron SW. Pyrethins, repellants, ... Poisoning and Drug Overdose . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 77. Cannon RD, Ruha A- ...

  15. Copper poisoning

    Science.gov (United States)

    ... Poisoning and Drug Overdose . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 75. Holland MG. Pulmonary toxicology. ... Poisoning and Drug Overdose . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 9. Jones AL, Dargan PI. ...

  16. Methylmercury poisoning

    Science.gov (United States)

    ... grain that was treated with this from of mercury. Poisoning from eating fish from water that is contaminated ... into the body. Many of the symptoms of mercury poisoning are similar to symptoms of cerebral palsy . In ...

  17. Merbromin poisoning

    Science.gov (United States)

    ... a vein (by IV) Laxatives Medicine called an antidote to reverse the effect of the poison Tube ... chance for recovery. If the person takes an antidote to reverse the poison within 1 week, recovery ...

  18. Control of the California Extremely Large Telescope primary mirror

    Science.gov (United States)

    MacMartin, Douglas G.; Chanan, Gary A.

    2003-01-01

    The current design concept for the California Extremely Large Telescope (CELT) includes 1080 segments in the primary mirror, with the out-of-plane degrees of freedom actively controlled. We construct the control matrix for this active control system, and describe its singular modes and sensor noise propagation. Data from the Keck telescopes are used to generate realistic estimates of the control system contributions to the CELT wavefront error and wavefront gradient error. Based on these estimates, control system noise will not significantly degrade either seeing-limited or diffraction-limited observations. The use of supplemental wavefront information for real-time control is therefore not necessary. We also comment briefly on control system bandwidth requirements and limitations.

  19. Alcohol Poisoning

    Science.gov (United States)

    ... t be awakened is at risk of dying. Alcohol poisoning is an emergency If you suspect that someone has alcohol poisoning — even if you don't see the ... immediately. Never assume the person will sleep off alcohol poisoning. Be prepared to provide information. If you ...

  20. Poison Prevention

    Science.gov (United States)

    ... Prevention Listen Español Text Size Email Print Share Poison Prevention Page Content Article Body Post the Poison Help number 1-800-222-1222 on the ... or empty container of a toxic substance, call Poison Help immediately. More than a million American children ...

  1. Photographic fixative poisoning

    Science.gov (United States)

    Photographic developer poisoning; Hydroquinone poisoning; Quinone poisoning; Sulfite poisoning ... Quinones Sodium thiosulfate Sodium sulfite/bisulfite Boric acid Photographic fixative can also break down (decompose) to form ...

  2. 78 FR 58460 - Revision of Air Quality Implementation Plan; California; Placer County Air Pollution Control...

    Science.gov (United States)

    2013-09-24

    ... Pollution Control District and Feather River Air Quality Management District; Stationary Source Permits... California as a revision to the Placer County Air Pollution Control District (PCAPCD) and Feather River Air... for the California SIP, Placer County Air Pollution Control District, Rule 502 (New Source...

  3. 75 FR 66771 - Advisory Committee on Childhood Lead Poisoning Prevention (ACCLPP)

    Science.gov (United States)

    2010-10-29

    ... HUMAN SERVICES Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning... lead poisoning prevention efforts. The committee also reviews and reports regularly on childhood lead poisoning prevention practices and recommends improvements in national childhood lead poisoning...

  4. Relationship between Personality Profiles and Suicide Attempt via Medicine Poisoning among Hospitalized Patients: A Case-Control Study.

    Science.gov (United States)

    Shafiee-Kandjani, Ali Reza; Amiri, Shahrokh; Arfaie, Asghar; Ahmadi, Azadeh; Farvareshi, Mahmoud

    2014-01-01

    Objectives. Inflexible personality traits play an important role in the development of maladaptive behaviors among patients who attempt suicide. This study was conducted to investigate the relationship between personality profiles and suicide attempt via medicine poisoning among the patients hospitalized in a public hospital. Materials and Methods. Fifty-nine patients who attempted suicide for the first time and hospitalized in the poisoning ward were selected as the experimental group. Sixty-three patients hospitalized in the other wards for a variety of reasons were selected as the adjusted control group. Millon Clinical Multiaxial Personality Inventory, 3rd version (MCMI-III) was used to assess the personality profiles. Results. The majority of the suicide attempters were low-level graduates (67.8% versus 47.1%, OR = 2.36). 79.7% of the suicide attempters were suffering from at least one maladaptive personality profile. The most common maladaptive personality profiles among the suicide attempters were depressive personality disorder (40.7%) and histrionic personality disorder (32.2%). Among the syndromes the most common ones were anxiety clinical syndrome (23.7%) and major depression (23.7%). Conclusion. Major depression clinical syndrome, histrionic personality disorder, anxiety clinical syndrome, and depressive personality disorder are among the predicators of first suicide attempts for the patients hospitalized in the public hospital due to the medicine poisoning.

  5. Poison Ivy Rash

    Science.gov (United States)

    Diseases and Conditions Poison ivy rash By Mayo Clinic Staff Poison ivy rash is caused by an allergic reaction to an oily resin ... is in the leaves, stems and roots of poison ivy, poison oak and poison sumac. Wash your ...

  6. Environmental Assessment:Security and Safety Upgrades to Entry Control Facilities Vandenberg Air Force Base, California

    Science.gov (United States)

    2016-06-07

    Security and Safety Upgrades to Entry Control Facilities 1-1 Vandenberg Air Force Base, California Chapter 1. Introduction : Purpose of and Need for the...woodland/Burton Mesa chaparral community. Dominant scrub species include California sagebrush and black sage (Salvia mellifera). The non-native...Grant, Campbell 1978a Chumash: Introduction . In California , edited by Robert F. Heizer, pp. 505–508. Handbook of North American Indians, vol. 8

  7. Compliance with infection control procedures among California orthodontists.

    Science.gov (United States)

    Woo, J; Anderson, R; Maguire, B; Gerbert, B

    1992-07-01

    We conducted a survey of a random sample of California orthodontists and of general dentists to compare their infection control procedures. Questionnaires were returned by 124 orthodontists (56% response rate) and 126 general dentists (61% response rate). Eighteen questions were asked covering practice profile, perception of risk from hepatitis B virus (HBV) and human immunodeficiency virus (HIV), exposure to blood, barrier protection used, and sterilization and disinfection procedures. Gloves always were worn by 80% of the orthodontists sampled, 63% always wore glasses, and 59% changed gloves between patients. Orthodontists sterilized their instruments 66% of the time and pliers 49% of the time. Compared with general dentists, orthodontists' perception of risk, use of barrier protection, and sterilization and disinfection procedures were lower in all areas. Our data suggest that poorer performance may be because orthodontists: (1) perceive their younger population of patients at less risk for HBV and HIV; (2) treat 2.5 times as many patients, which increases the costs of infection control; (3) do not use invasive procedures; and (4) perceive that glove use decreases dexterity. Orthodontists should follow the American Dental Association/Council on Dental Therapeutics infection control guidelines for universal precautions. To meet these guidelines, orthodontists still need improvement in all aspects of their infection control procedures.

  8. Effect of a brief outreach educational intervention on the translation of acute poisoning treatment guidelines to practice in rural Sri Lankan hospitals: a cluster randomized controlled trial.

    Directory of Open Access Journals (Sweden)

    Lalith Senarathna

    Full Text Available BACKGROUND: In developing countries, including Sri Lanka, a high proportion of acute poisoning and other medical emergencies are initially treated in rural peripheral hospitals. Patients are then usually transferred to referral hospitals for further treatment. Guidelines are often used to promote better patient care in these emergencies. We conducted a cluster randomized controlled trial (ISRCTN73983810 which aimed to assess the effect of a brief educational outreach ('academic detailing' intervention to promote the utilization of treatment guidelines for acute poisoning. METHODS AND FINDINGS: This cluster RCT was conducted in the North Central Province of Sri Lanka. All peripheral hospitals in the province were randomized to either intervention or control. All hospitals received a copy of the guidelines. The intervention hospitals received a brief out-reach academic detailing workshop which explained poisoning treatment guidelines and guideline promotional items designed to be used in daily care. Data were collected on all patients admitted due to poisoning for 12 months post-intervention in all study hospitals. Information collected included type of poison exposure, initial investigations, treatments and hospital outcome. Patients transferred from peripheral hospitals to referral hospitals had their clinical outcomes recorded. There were 23 intervention and 23 control hospitals. There were no significant differences in the patient characteristics, such as age, gender and the poisons ingested. The intervention hospitals showed a significant improvement in administration of activated charcoal [OR 2.95 (95% CI 1.28-6.80]. There was no difference between hospitals in use of other decontamination methods. CONCLUSION: This study shows that an educational intervention consisting of brief out-reach academic detailing was effective in changing treatment behavior in rural Sri Lankan hospitals. The intervention was only effective for treatments with

  9. 76 FR 71922 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-11-21

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air Pollution Control District and Sacramento Metropolitan Air Quality Management District AGENCY: Environmental... County Air Pollution Control District (PCAPCD) and Sacramento Metropolitan Air Quality...

  10. 77 FR 73322 - Revisions to the California State Implementation Plan, Monterey Bay Unified Air Pollution Control...

    Science.gov (United States)

    2012-12-10

    ... Part 52 Environmental protection, Air pollution control, Incorporation by reference, Intergovernmental... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Monterey Bay Unified Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule....

  11. 75 FR 8008 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2010-02-23

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY... Pollution Control District (ICAPCD) portion of the California State Implementation Plan (SIP). These... construction sites, unpaved roads, and disturbed soils in open and agricultural areas. We are proposing...

  12. Zinc poisoning

    Science.gov (United States)

    ... Hill; 2006. Hall AH, Shannon MW. Other heavy metals. In: Shannon MW, Borron SW, Burns MJ,eds. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose . 4th ed. Philadelphia, PA. Elsevier ...

  13. Shellac poisoning

    Science.gov (United States)

    ... in shellac that can be harmful are: Ethanol Isopropanol Methanol Methyl isobutyl ketone ... Isopropanol and methanol are extremely poisonous. As little as 2 tablespoons (14.8 mL) of methanol can ...

  14. Arsenic poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Low, D.G.

    1974-01-01

    The use of arsenic in ant poisons, herbicides, and insecticides affords the necessary contact with the poison by pets. The gastrointestinal tract appears to suffer the greatest though there may also be injury to the liver and kidneys. The treatments discussed were in relation to very early poisoning in which the owner had observed ingestion of the arsenic, and when the signs of the poisoning were evident. Early observation treatment included emptying the stomach before the arsenic passed in quantity into the intestine. If the signs of toxicity were already advanced, then the treatment consisted of the intramuscular administration of dimercaprol (BAL) at a dosage of 3 mg/lb of body weight three times a day until recovery. l reference.

  15. Arsenic poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Low, D.G.

    1971-01-01

    The use of arsenic in ant poisons, herbicides, and insecticides affords the necessary contact with the poison by pets. Treatment was discussed in relation to two circumstances: very early poisoning in which the owner has observed ingestion of the arsenic, and when the signs of the poisoning are evident. Treatment for early ingestion involves emptying the stomach before the arsenic can pass in quantity into the intestine. This is followed with a 1% solution of sodium bicarbonate, with the administering of 3 to 6 mg of apomorphine. When signs of arsenic toxicity are already advanced, there is little advantage to be gained by either gastric lavage or administration of an emetic. The treatment then consists of the intramuscular administration of dimercaprol (BAL) at a dosage of 3 mg/lb of body weight three times a day until recovery. This is the specific antidote for arsenic. 1 reference.

  16. Paraffin poisoning

    Science.gov (United States)

    Wax poisoning - paraffin ... Paraffin ... Eating a lot of paraffin can lead to intestinal obstruction, which can cause abdominal pain, nausea, vomiting, and possible constipation. If the paraffin contains a ...

  17. Food poisoning

    Science.gov (United States)

    ... and toxins may cause food poisoning, including: Campylobacter enteritis Cholera E. coli enteritis Toxins in spoiled or tainted fish or shellfish ... Read More Botulism Campylobacter infection Cholera E. coli enteritis Fish tapeworm infection Pericarditis Salmonella enterocolitis Shigellosis Patient ...

  18. Menthol poisoning

    Science.gov (United States)

    Menthol is used to add peppermint flavor to candy and other products. It is also used in certain skin lotions and ointments. This article discusses menthol poisoning from swallowing pure menthol. This article is ...

  19. Naphthalene poisoning

    Science.gov (United States)

    ... K. General approach to the poisoned patient. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ... 147. Levine MD, Zane R. Chemical injuries. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ...

  20. Ammonia poisoning

    Science.gov (United States)

    ... K. General approach to the poisoned patient. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ... 147. Levine MD, Zane R. Chemical injuries. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ...

  1. 77 FR 53199 - California State Motor Vehicle Pollution Control Standards; Advanced Clean Car Program; Request...

    Science.gov (United States)

    2012-08-31

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Advanced Clean Car Program; Request... California Air Resources Board (CARB) has notified EPA that it has developed an Advanced Clean Car program... into a single coordinated package of requirements for passenger cars, light-duty trucks and...

  2. Spatial and temporal controls on Southern California's large fires

    Science.gov (United States)

    Jin, Y.; Hall, A. D.; Randerson, J. T.; Goulden, M.

    2010-12-01

    The largest and most destructive fires in Southern California occur during intense Santa Ana wind events. Predicting how these fires and subsequent impacts on ecosystem recovery, air quality, and human health are likely to change in the future requires an understanding of how fire weather, vegetation, and land use control contemporary fires and how they interact. We combined a multi-decade reconstruction of climate at 6 km resolution simulated with MM5 and a long term record of vegetation conditions at 1 km resolution derived from AVHRR and MODIS satellites to examine the spatial and temporal patterns of large fires from 1990 to 2008 as reported in California’s Fire and Resource Assessment Program (FRAP) historical fire perimeter data. Various statistical tests were performed to examine the controls for fire frequency and fire size, from both spatial and interannual perspectives. We constructed empirical models of fire occurrence and burned area for each ecological unit as a function of vegetation composition, fire weather, antecedent climate, and human activities. This study has policy implications for large fire management and mitigation strategies.

  3. The power of poison: pesticide poisoning of Africa's wildlife.

    Science.gov (United States)

    Ogada, Darcy L

    2014-08-01

    Poisons have long been used to kill wildlife throughout the world. An evolution has occurred from the use of plant- and animal-based toxins to synthetic pesticides to kill wildlife, a method that is silent, cheap, easy, and effective. The use of pesticides to poison wildlife began in southern Africa, and predator populations were widely targeted and eliminated. A steep increase has recently been observed in the intensity of wildlife poisonings, with corresponding population declines. However, the majority of poisonings go unreported. Under national laws, it is illegal to hunt wildlife using poisons in 83% of African countries. Pesticide regulations are inadequate, and enforcement of existing legislation is poor. Few countries have forensic field protocols, and most lack storage and testing facilities. Methods used to poison wildlife include baiting carcasses, soaking grains in pesticide solution, mixing pesticides to form salt licks, and tainting waterholes. Carbofuran is the most widely abused pesticide in Africa. Common reasons for poisoning are control of damage-causing animals, harvesting fish and bushmeat, harvesting animals for traditional medicine, poaching for wildlife products, and killing wildlife sentinels (e.g., vultures because their aerial circling alerts authorities to poachers' activities). Populations of scavengers, particularly vultures, have been decimated by poisoning. Recommendations include banning pesticides, improving pesticide regulations and controlling distribution, better enforcement and stiffer penalties for offenders, increasing international support and awareness, and developing regional pesticide centers.

  4. Arsenic poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Schoolmeester, W.L.; White, D.R.

    1980-02-01

    Arsenic poisoning continues to require awareness of its diverse clinical manifestations. Industry is the major source of arsenic exposure. Although epidemiologic studies strongly contend that arsenic is carcinogenic, there are little supportive research data. Arsenic poisoning, both acute and chronic, is often overlooked initially in the evaluation of the patient with multisystem disease, but once it is suspected, many accurate methods are available to quantitate the amount and duration of exposure. Treatment with dimercaprol remains the mainstay of therapy, and early treatment is necessary to prevent irreversible complications.

  5. 75 FR 3996 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

    Science.gov (United States)

    2010-01-26

    ... Planning, San Joaquin Valley Air Pollution Control District; letter dated and received August 17, 2009... Sadredin, Executive Director/Air Pollution Control Officer of San Joaquin Valley Air Pollution Control... emission control requirements of Rule 4684 are consistent with the California Air Resources Board's...

  6. 76 FR 30080 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-05-24

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air Pollution Control District and Ventura County Air Pollution Control District AGENCY: Environmental Protection Agency... Pollution Control District (PCAPCD) and Ventura County Air Pollution Control District (VCAPCD) portion...

  7. Effect of the California tobacco control program on personal health care expenditures.

    Directory of Open Access Journals (Sweden)

    James M Lightwood

    2008-08-01

    Full Text Available BACKGROUND: Large state tobacco control programs have been shown to reduce smoking and would be expected to affect health care costs. We investigate the effect of California's large-scale tobacco control program on aggregate personal health care expenditures in the state. METHODS AND FINDINGS: Cointegrating regressions were used to predict (1 the difference in per capita cigarette consumption between California and 38 control states as a function of the difference in cumulative expenditures of the California and control state tobacco control programs, and (2 the relationship between the difference in cigarette consumption and the difference in per capita personal health expenditures between the control states and California between 1980 and 2004. Between 1989 (when it started and 2004, the California program was associated with $86 billion (2004 US dollars (95% confidence interval [CI] $28 billion to $151 billion lower health care expenditures than would have been expected without the program. This reduction grew over time, reaching 7.3% (95% CI 2.7%-12.1% of total health care expenditures in 2004. CONCLUSIONS: A strong tobacco control program is not only associated with reduced smoking, but also with reductions in health care expenditures.

  8. 76 FR 61095 - California State Motor Vehicle Pollution Control Standards; Within the Scope Determination and...

    Science.gov (United States)

    2011-10-03

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Within the Scope Determination and... certification, inspection or any other approval relating to the control of emissions from any new motor vehicle...) for the control of emissions from new motor vehicles or new motor engines prior to March 30,...

  9. 77 FR 9916 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo...

    Science.gov (United States)

    2012-02-21

    ... AGENCY California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo... to the control of emissions from new motor vehicles or new motor vehicle engines ] EPA is, pursuant... standards relating to the control of emissions for new motor vehicles and new motor vehicle...

  10. 78 FR 51724 - California State Motor Vehicle Pollution Control Standards; Tractor-Trailer Greenhouse Gas...

    Science.gov (United States)

    2013-08-21

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Tractor-Trailer Greenhouse Gas... shall adopt or attempt to enforce any standard relating to the control of emissions from new motor..., inspection or any other approval relating to the control of emissions from any new motor vehicle or new...

  11. 76 FR 34693 - California State Motor Vehicle Pollution Control Standards; Within-the-Scope Determination for...

    Science.gov (United States)

    2011-06-14

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Within-the-Scope Determination for... or attempt to enforce any standard relating to the control of emissions from new motor vehicles or... any other approval relating to the control of emissions from any new motor vehicle or new...

  12. 76 FR 5368 - California State Motor Vehicle Pollution Control Standards; Greenhouse Gas Regulations; Within...

    Science.gov (United States)

    2011-01-31

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Greenhouse Gas Regulations; Within-the... thereof shall adopt or attempt to enforce any standard relating to the control of emissions from new motor..., inspection or any other approval relating to the control of emissions from any new motor vehicle or new...

  13. Recognizing the Toxicodendrons (poison ivy, poison oak, and poison sumac).

    Science.gov (United States)

    Guin, J D; Gillis, W T; Beaman, J H

    1981-01-01

    Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of poison ivy, Toxicodendron rydbergii, a nonclimbing subshrub, and Toxicodendron radicans, which may be either a shrub or a climbing vine. There are nine subspecies of T. radicans, six of which are found in the United States. One species of poison sumac, Toxicodendron vernix, occurs in the United States. Distinguishing features of these plants and characteristics that separate Toxicodendron from Rhus are outlined in the text and illustrated in color plates.

  14. Mercuric oxide poisoning

    Science.gov (United States)

    ... of mercury salt. There are different types of mercury poisonings . This article discusses poisoning from swallowing mercuric oxide. ... Disinfectants Fungicides There have been reports of inorganic mercury poisoning from the use of skin-lightening creams. Note: ...

  15. 78 FR 721 - California State Nonroad Engine Pollution Control Standards; Transport Refrigeration Units...

    Science.gov (United States)

    2013-01-04

    ... AGENCY California State Nonroad Engine Pollution Control Standards; Transport Refrigeration Units... Transport Refrigeration Units (TRU) and TRU Generator Sets and Facilities Where TRUs Operate.'' CARB has...''), regarding its ``Airborne Toxic Control Measure for In-Use Diesel-Fueled Transport Refrigeration Units...

  16. 78 FR 896 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2013-01-07

    ... is finalizing approval of revisions to the Imperial County Air Pollution Control District (ICAPCD...)(2)). List of Subjects in 40 CFR Part 52 Environmental protection, Air pollution control... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Imperial County...

  17. 77 FR 73392 - Revisions to the California State Implementation Plan, Monterey Bay Unified Air Pollution Control...

    Science.gov (United States)

    2012-12-10

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Monterey Bay Unified Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Monterey Bay Unified Air Pollution Control...

  18. 76 FR 17347 - Revision to the California State Implementation Plan, Great Basin Unified Air Pollution Control...

    Science.gov (United States)

    2011-03-29

    ...) * * * (D) Great Basin Unified Air Pollution Control District (1) Rule 201, ``Exemptions,'' adopted on... AGENCY 40 CFR Part 52 Revision to the California State Implementation Plan, Great Basin Unified Air Pollution Control District CFR Correction In Title 40 of the Code of Federal Regulations, Part 52 (Sec....

  19. 75 FR 2079 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

    Science.gov (United States)

    2010-01-14

    ... facilities. Also, please see our response to CPF comment 3. B. San Joaquin Valley Air Pollution Control...) San Joaquin Valley Unified Air Pollution Control District. (1) Rule 4570, ``Confined Animal Facilities... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, San Joaquin Valley...

  20. 76 FR 60405 - Revisions to the California State Implementation Plan, Santa Barbara Air Pollution Control...

    Science.gov (United States)

    2011-09-29

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Santa Barbara Air Pollution Control District, Sacramento Municipal Air Quality Management District and South Coast Air Quality... proposing to approve revisions to the Santa Barbara Air Pollution Control District (SBAPCD),...

  1. 75 FR 56942 - Revisions to the California State Implementation Plan, San Diego County Air Pollution Control...

    Science.gov (United States)

    2010-09-17

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, San Diego County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the San Diego Air Pollution Control District...

  2. 78 FR 37176 - Revisions to the California State Implementation Plan, San Diego Air Pollution Control District

    Science.gov (United States)

    2013-06-20

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, San Diego Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve a revision to the San Diego Air Pollution Control District (SDAPCD) portion of...

  3. 78 FR 53249 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2013-08-29

    ... finalizing approval of revisions to the Placer County Air Pollution Control District (PCAPCD) portion of the... 40 CFR Part 52 Environmental protection, Air pollution control, Incorporation by reference... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air...

  4. 78 FR 6784 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2013-01-31

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Placer County Air Pollution Control District (PCAPCD) portion of...

  5. 77 FR 2643 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2012-01-19

    ... finalizing a limited approval and limited disapproval of revisions to the Placer County Air Pollution Control...) * * * (i) * * * (D) Placer County Air Pollution Control District (1) Rule 233, ``Biomass Boilers,'' amended... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air...

  6. Rare earths as burnable poison for extended cycles control in electricity generation reactors; Etude des terres rares en tant que poison consommable pour le controle des cycles allonges pour les reacteurs electrogenes

    Energy Technology Data Exchange (ETDEWEB)

    Asou, M.

    1995-05-12

    The search of an optimization of the French electronuclear network operations leads to a necessary optimization of the core performances. All the economic studies performed by the utilities had shown that there is a real gain to minimize shut down periods for refueling. So, increasing the cycle length from 12 to 18 months will present a gain of shut down for a three years operation period. The theoretical burnable absorber will be a fuel admixed material bringing the required initial negative reactivity with a burn-up kinetic well suited to the fuel and allowing the lowest residual penalty as possible. The residual penalty us defined in this case by the non complete burn up of the poison, by the low of fissile material and by the accumulate of residual isotopes or nuclides. Because of the well known use of gadolinium as burnable absorber for BWR`s and PWR`s operations, the search for the best compromise to optimize all the above stress is pointed towards the rare earths. In the nuclides family, considering criteria such as cross sections, natural abundance and availability only five nuclides can play the role as burnable absorbers, namely: gadolinium, samarium, dysprosium, europium and erbium. The study presented here will show that only gadolinium and erbium will be considered to control the reactivity of the PWR`s. (author). 58 refs., 65 figs., 47 tabs.

  7. 76 FR 62071 - Advisory Committee on Childhood Lead Poisoning Prevention(ACCLPP)

    Science.gov (United States)

    2011-10-06

    ... HUMAN SERVICES Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning... developments and their practical implications for childhood lead poisoning prevention efforts. The committee also reviews and reports regularly on childhood lead poisoning prevention practices and...

  8. Effect of melatonin on duration of delirium in organophosphorus compound poisoning patients: A double-blind randomised placebo controlled trial

    Directory of Open Access Journals (Sweden)

    H N Vijayakumar

    2016-01-01

    Full Text Available Background and Aims: Organophosphate compound poisoning (OPCP is associated with high incidence of delirium. Melatonin has been tried in the treatment of delirium and has shown a beneficial effect in OPCP. This study was conducted to know the effect of melatonin on duration of delirium and recovery profile in OPCP patients. Methods: Double-blind randomised placebo control trial in which 56 patients of OPCP confirmed by history and syndrome of OPCP with low plasma pseudocholinesterase, aged >18 years and weighing between 50 and 100 kg, and Acute Physiology and Chronic Health Evaluation II score of <20 were studied. Group M (n = 26 received tablet melatonin 3 mg and Group C (n = 30 received placebo tablet at 9 PM, every night throughout the Intensive Care Unit (ICU stay. Delirium was assessed using the Confusion Assessment Method for ICU, thrice a day. Sedation was provided with injection midazolam, fentanyl and lorazepam. Duration of mechanical ventilation, vital parameters, ICU stay, sedative and atropine requirement, were recorded. Results: The time taken to be delirium free was significantly lower in Group M (6 ± 2.92 days compared to Group C (9.05 ± 2.75 days (P = 0.001 and prevalence of delirium was significantly decreased in Group M compared to Group C from day 3 onwards. The requirement of midazolam (Group M - 2.98 ± 4.99 mg/day, Group C - 9.68 ± 9.17 mg/day, P < 0.001 and fentanyl (Group M - 94.09 ± 170.05 μg/day, Group C - 189.33 ± 156.38 μg/day, P = 0.03 decreased significantly in Group M. There was no significant difference in the average atropine consumption (P = 0.27, duration of mechanical ventilation (P = 0.26, ICU stay (P = 0.21 and the number of patients requiring mechanical ventilation (P = 0.50. Conclusion: Orally given melatonin in organophosphate compound poisoning patients reduces the duration of delirium and the requirement of sedation and analgesia.

  9. Marijuana poisoning.

    Science.gov (United States)

    Fitzgerald, Kevin T; Bronstein, Alvin C; Newquist, Kristin L

    2013-02-01

    , tremors, hypothermia, and bradycardia. Higher dosages may additionally cause nystagmus, agitation, tachypnea, tachycardia, ataxia, hyperexcitability, and seizures. Treatment of marijuana ingestion in animals is largely supportive. Vital signs including temperature and heart rate and rhythm must be continually monitored. Stomach content and urine can be tested for cannabinoids. Gas chromatography and mass spectrometry can be utilized for THC detection but usually may take several days and are not practical for initiation of therapy. Human urine drug-screening tests can be unreliable for confirmation of marijuana toxicosis in dogs owing to the interference of a large number of the metabolites in canine urine. False negatives may also arise if testing occurs too recently following THC ingestion. Thus, the use of human urine drug-screening tests in dogs remains controversial. No specific antidote presently exists for THC poisoning. Sedation with benzodiazepines may be necessary if dogs are severely agitated. Intravenous fluids may be employed to counter prolonged vomiting and to help control body temperature. Recently, the use of intralipid therapy to bind the highly lipophilic THC has been utilized to help reduce clinical signs. The majority of dogs experiencing intoxication after marijuana ingestion recover completely without sequellae. Differential diagnoses of canine THC toxicosis include human pharmaceuticals with central nervous system stimulatory effects, drugs with central nervous system depressant effects, macrolide parasiticides, xylitol, and hallucinogenic mushrooms.

  10. House of Poison: Poisons in the Home.

    Science.gov (United States)

    Keller, Rosanne

    One of a series of instructional materials produced by the Literacy Council of Alaska, this booklet provides information about common household poisons. Using a simplified vocabulary and shorter sentences, it provides statistics concerning accidental poisonings; a list of the places poisons are usually found in the home; steps to make the home…

  11. Evaluation of variability and quality control procedures for a receptor-binding assay for paralytic shellfish poisoning toxins.

    Science.gov (United States)

    Ruberu, S R; Langlois, G W; Masuda, M; Perera, S Kusum

    2012-01-01

    The receptor-binding assay (RBA) method for determining saxatoxin (STX) and its numerous analogues, which cause paralytic shellfish poisoning (PSP) in humans, was evaluated in a single laboratory study. Each step of the assay preparation procedure including the performance of the multi-detector TopCount® instrument was evaluated for its contribution to method variability. The overall inherent RBA variability was determined to be 17%. Variability within the 12 detectors was observed; however, there was no reproducible pattern in detector performance. This observed variability among detectors could be attributed to other factors, such as pipetting errors. In an attempt to reduce the number of plates rejected due to excessive variability in the method's quality control parameters, a statistical approach was evaluated using either Grubbs' test or the Student's t-test for rejecting outliers in the measurement of triplicate wells. This approach improved the ratio of accepted versus rejected plates, saving cost and time for rerunning the assay. However, the potential reduction in accuracy and the lack of improvement in precision suggests caution when using this approach. The current study has recommended an alternate quality control procedure for accepting or rejecting plates in place of the criteria currently used in the published assay, or the alternative of outlier testing. The recommended procedure involves the development of control charts to monitor the critical parameters identified in the published method (QC sample, EC₅₀, slope of calibration curve), with the addition of a fourth critical parameter which is the top value (100% binding) of the calibration curve.

  12. 77 FR 73459 - California State Motor Vehicle Pollution Control Standards; Notice of Waiver of Clean Air Act...

    Science.gov (United States)

    2012-12-10

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Notice of Waiver of Clean Air Act..., challenging the need for CARB's own motor vehicle pollution control program based on lack of compelling and... Administrator shall waive preemption for California to enforce new motor vehicle emissions standards...

  13. [Effect analysis on the two total load control methods for poisonous heavy metals].

    Science.gov (United States)

    Fu, Guo-Wei

    2012-12-01

    Firstly it should be made clear that implementation of source total load control for the first type of pollutants is necessary for environmental pollution control legislation and economic structure regulation. This kind of surveillance method has been more practical to be implemented since the Manual of the Industry Discharge Coefficient of First National Pollution Sources Investigation was published. The source total load control and water environment total load control are independent of each other and none of them is redundant, on the other side they can be complementary to each other. In the present, some local planning managers are blurring and confusing the contents and styles of the two surveillance methods. They just use the water total load control to manage all the pollutants, and source total load control is discarded, which results in the loss of control for the first type of pollutants especially for the drinking water source surveillance. There is a big difference between the water quality standards and the water environmental background concentration values for the first type of pollutants in the Environmental quality standard for surface water (GB 3838-88), which means that there are problems such as "relaxing the pollutant discharge permit" and "risk induced by valence state change". Taking an enterprise with 10t electrolytic lead production capacity as an example, there is a big difference between the allowable lead discharged loads by the two total load surveillance methods. In summary, it will bring a lot of harmful effects if the water total load control is implemented for the two types of pollutants, so the source total load control and water environmental total load control should be implemented strictly at the same time.

  14. [Mercury poisoning].

    Science.gov (United States)

    Bensefa-Colas, L; Andujar, P; Descatha, A

    2011-07-01

    Mercury is a widespread heavy metal with potential severe impacts on human health. Exposure conditions to mercury and profile of toxicity among humans depend on the chemical forms of the mercury: elemental or metallic mercury, inorganic or organic mercury compounds. This article aims to reviewing and synthesizing the main knowledge of the mercury toxicity and its organic compounds that clinicians should know. Acute inhalation of metallic or inorganic mercury vapours mainly induces pulmonary diseases, whereas chronic inhalation rather induces neurological or renal disorders (encephalopathy and interstitial or glomerular nephritis). Methylmercury poisonings from intoxicated food occurred among some populations resulting in neurological disorders and developmental troubles for children exposed in utero. Treatment using chelating agents is recommended in case of symptomatic acute mercury intoxication; sometimes it improves the clinical effects of chronic mercury poisoning. Although it is currently rare to encounter situations of severe intoxication, efforts remain necessary to decrease the mercury concentration in the environment and to reduce risk on human health due to low level exposure (dental amalgam, fish contamination by organic mercury compounds…). In case of occupational exposure to mercury and its compounds, some disorders could be compensated in France. Clinicians should work with toxicologists for the diagnosis and treatment of mercury intoxication.

  15. Mania following organophosphate poisoning

    Directory of Open Access Journals (Sweden)

    Satyakam Mohapatra

    2014-01-01

    Full Text Available Organophosphate poisoning is the most common poisoning in developing countries. Although the acute muscarinic and nicotinic side-effects of organophosphate poisoning are well known and easily recognized, but neuropsychiatric changes are rarely reported. We are reporting a case of a 33-year-old female who developed manic episode following acute organophosphate poisoning.

  16. Mania following organophosphate poisoning

    OpenAIRE

    Satyakam Mohapatra; Neelmadhav Rath

    2014-01-01

    Organophosphate poisoning is the most common poisoning in developing countries. Although the acute muscarinic and nicotinic side-effects of organophosphate poisoning are well known and easily recognized, but neuropsychiatric changes are rarely reported. We are reporting a case of a 33-year-old female who developed manic episode following acute organophosphate poisoning.

  17. Mania following organophosphate poisoning.

    Science.gov (United States)

    Mohapatra, Satyakam; Rath, Neelmadhav

    2014-11-01

    Organophosphate poisoning is the most common poisoning in developing countries. Although the acute muscarinic and nicotinic side-effects of organophosphate poisoning are well known and easily recognized, but neuropsychiatric changes are rarely reported. We are reporting a case of a 33-year-old female who developed manic episode following acute organophosphate poisoning.

  18. 77 FR 67322 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2012-11-09

    ... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, Placer County Air Pollution... proposing to approve revisions to the Placer County Air Pollution Control District (PCAPCD) portion of the... authority to address disproportionate human health or environmental effects with practical, appropriate,...

  19. Biological Control of Olive Fruit Fly in California with a Parasitoid Imported from Guatemala

    Science.gov (United States)

    The parasitoid, Psyttalia cf. concolor (Szépligeti), was imported into California from the USDA-APHIS-PPQ, Moscamed, San Miguel Petapa, Guatemala for biological control of olive fruit fly, Bactrocera oleae (Gmelin), in olives, Olea europaea L. The parasitoid did not develop in the seedhead fly, Cha...

  20. 78 FR 719 - California State Motor Vehicle Pollution Control Standards; Urban Buses; Request for Waiver of...

    Science.gov (United States)

    2013-01-04

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Urban Buses; Request for Waiver of... amendments to its emission standards for urban bus engines in a series of rulemakings. The rulemakings at... public transit agencies that operate urban buses and other transit vehicles; additionally,...

  1. 78 FR 44112 - California State Motor Vehicle Pollution Control Standards; Urban Buses; Request for Waiver of...

    Science.gov (United States)

    2013-07-23

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Urban Buses; Request for Waiver of... for emission standards and related test procedures contained in its urban bus regulations as they affect the 2002 and later model years. Urban buses are conventionally powered by a heavy-duty...

  2. Postharvest fumigation of California table grapes with ozone to control Western black widow spider (Araneae: Theridiidae)

    Science.gov (United States)

    Ozone fumigations were evaluated for postharvest control of Western black widow spider (BWS), Latrodectus hesperus (Chamberlin and Ivie), in fresh table grapes destined for export from California USA. Mature adult female black widow spiders were contained in separate gas-permeable cages within a flo...

  3. Ciguatera poisoning.

    Science.gov (United States)

    Achaibar, Kira C; Moore, Simon; Bain, Peter G

    2007-10-01

    Ciguatera is a form of poisoning that occurs after eating tropical and subtropical ciguatoxic fish. The ciguatoxins are a family of heat stable, lipid soluble cyclic polyether compounds that bind to and open voltage-sensitive Na(+) channels at resting membrane potential, resulting in neural hyperexcitability, as well as swelling of the nodes of Ranvier. The authors describe a 45-year-old man who developed acute gastrointestinal symptoms in Antigua soon after eating red snapper and grouper, potentially "ciguatoxic fish". This was followed by neurological symptoms 24-48 hours later, including temperature reversal (paradoxical dysaesthesia), intense pruritus and increased nociception as a result of a small fibre peripheral neuropathy. The patient's symptoms and small fibre neuropathy improved over a period of 10 months.

  4. Climate controls on valley fever incidence in Kern County, California

    Science.gov (United States)

    Zender, Charles S.; Talamantes, Jorge

    2006-01-01

    Coccidiodomycosis (valley fever) is a systemic infection caused by inhalation of airborne spores from Coccidioides immitis, a soil-dwelling fungus found in the southwestern United States, parts of Mexico, and Central and South America. Dust storms help disperse C. immitis so risk factors for valley fever include conditions favorable for fungal growth (moist, warm soil) and for aeolian soil erosion (dry soil and strong winds). Here, we analyze and inter-compare the seasonal and inter-annual behavior of valley fever incidence and climate risk factors for the period 1980-2002 in Kern County, California, the US county with highest reported incidence. We find weak but statistically significant links between disease incidence and antecedent climate conditions. Precipitation anomalies 8 and 20 months antecedent explain only up to 4% of monthly variability in subsequent valley fever incidence during the 23 year period tested. This is consistent with previous studies suggesting that C. immitis tolerates hot, dry periods better than competing soil organisms and, as a result, thrives during wet periods following droughts. Furthermore, the relatively small correlation with climate suggests that the causes of valley fever in Kern County could be largely anthropogenic. Seasonal climate predictors of valley fever in Kern County are similar to, but much weaker than, those in Arizona, where previous studies find precipitation explains up to 75% of incidence. Causes for this discrepancy are not yet understood. Higher resolution temporal and spatial monitoring of soil conditions could improve our understanding of climatic antecedents of severe epidemics.

  5. RAPID MULTICOMPONENT ANALYSIS OF HEMOGLOBIN DERIVATIVES FOR CONTROLLED ANTIDOTAL USE OF METHEMOGLOBIN-FORMING AGENTS IN CYANIDE POISONING

    NARCIS (Netherlands)

    ZIJLSTRA, WG

    1993-01-01

    When cyanide poisoning is treated with a methemoglobin-forming agent, oxidative metabolism is protected at the expense of the oxygen capacity of the blood.The affinity of methemoglobin for CN- is high enough to compete with cytochrome oxidase, which protects the latter from becoming blocked, but all

  6. Effect of Systematic Follow-Up by General Practitioners after Deliberate Self-Poisoning: A Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Tine K Grimholt

    Full Text Available To assess whether systematic follow-up by general practitioners (GPs of cases of deliberate self-poisoning (DSP by their patients decreases psychiatric symptoms and suicidal behaviour compared with current practice.Randomised clinical trial with two parallel groups.General practices in Oslo and the eastern part of Akershus County.Patients aged 18-75 years admitted to hospital for DSP. We excluded patients diagnosed with psychoses, without a known GP, those not able to complete a questionnaire, and patients admitted to psychiatric in-patient care or other institutions where their GP could not follow them immediately after discharge.The GPs received a written guideline, contacted the patients and scheduled a consultation within one week after discharge, and then provided regular consultations for six months. We randomised the patients to either intervention (n = 78 or treatment as usual (n = 98.Primary outcome measure was the Beck Scale for Suicide Ideation (SSI. Secondary outcomes were Beck Depression Inventory (BDI and Beck Hopelessness Scale (BHS, self-reported further self-harm and treatment for DSP in a general hospital or an emergency medical agency (EMA. We assessed patients on entry to the trial and at three and six months. We collected data from interviews, self-report questionnaires, and hospital and EMA medical records.There were no significant differences between the groups in SSI, BDI, or BHS mean scores or change from baseline to three or six months. During follow-up, self-reported DSP was 39.5% in the intervention group vs. 15.8% in controls (P = 0.009. Readmissions to general hospitals were similar (13% in both groups (P = 0.963, while DSP episodes treated at EMAs were 17% in the intervention group and 7% in the control group (P = 0.103.Structured follow-up by GPs after an episode of DSP had no significant effect on suicide ideation, depression or hopelessness. There was no significant difference in repeated episodes of DSP in

  7. Pest control plan Modoc National Wildlife Refuge Alturas California

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this plan is to receive approval to control both wildlife and domestic animals in order to meet refuge goals and objectives. Refuge objectives were...

  8. Poison Ivy Dermatitis

    Science.gov (United States)

    ... Favorite Name: Category: Share: Yes No, Keep Private Poison Ivy Dermatitis Share | "Leaves of three - let it ... has a longer stem than the other two. Poison ivy clings to tree trunks and other vertical ...

  9. Plant fertilizer poisoning

    Science.gov (United States)

    Plant fertilizers and household plant foods are used to improve plant growth. Poisoning can occur if someone swallows these products. Plant fertilizers are mildly poisonous if small amounts are swallowed. ...

  10. Lead Poisoning in Children.

    Science.gov (United States)

    Drummond, A. H., Jr.

    1981-01-01

    Early symptoms of lead poisoning in children are often overlooked. Lead poisoning has its greatest effects on the brain and nervous system. The obvious long-term solution to the lead poisoning problem is removal of harmful forms of the metal from the environment. (JN)

  11. Meteorological Controls on Biomass Burning During Santa Ana Events in Southern California

    Science.gov (United States)

    Veraverbeke, Sander; Capps, Scott; Hook, Simon J.; Randerson, James T.; Jin, Yufang; Hall, Alex

    2013-01-01

    Fires occurring during Santa Ana (SA) events in southern California are driven by extreme fire weather characterized by high temperatures, low humidities, and high wind speeds. We studied the controls on burned area and carbon emissions during two intensive SA burning periods in 2003 and 2007. We therefore used remote sensing data in parallel with fire weather simulations of the Weather and Regional Forecast model. Total carbon emissions were approximately 1800 gigagrams in 2003 and 900 gigagrams in 2007, based on a daily burned area and a fire emission model that accounted for spatial variability in fuel loads and combustion completeness. On a regional scale, relatively strong positive correlations were found between the daily Fosberg fire weather index and burned area/emissions (probability is less than 0.01). Our analysis provides a quantitative assessment of relationships between fire activity and weather during severe SA fires in southern California.

  12. Lead poisoning in six captive avian species

    Science.gov (United States)

    Beyer, W.N.; Spann, J.W.; Sileo, L.; Franson, J.C.

    1988-01-01

    Red-winged blackbirds (Agelaius phoeniceus), brown-headed cowbirds (Molothrus ater), common grackles (Quiscalus quiscula), mallards (Anas platyrhynchos), northern bobwhites (Colinus virginianus), and eastern screech-owls (Otus asio) were poisoned with a concentration of lead (Pb) acetate in the diet which was increased by 60% each week until half of the birds in each treatment group died; surviving birds and all control birds except screech-owls were then killed by euthanasia. An additional group of mallards was poisoned with Pb shot. The gizzards of mallards poisoned either way usually were stained with bile; some of these birds also had proventricular impaction. Most poisoned birds of the other species were emaciated but lacked other gross lesions caused by Pb poisoning. In birds other than mallards, Pb poisoning could not be diagnosed without histological or hematological examinations or analysis of tissues. Poisoned birds of all six species could be reliably separated from control birds by an increase in the protoporphyrin concentrations in the blood and by a decrease in the activity of delta-aminoievulinic acid dehydratase (ALAD) in red blood cells. Hepatic iron (Fe) concentrations varied so much among individual birds that even though median hepatic Fe concentrations increased in poisoned birds, hepatic Fe concentrations were not useful in identifying poisoned birds. Renal intranuclear inclusion bodies occurred in 83% of all birds dying from Pb poisoning. Nephrosis, myocardial necrosis, and arterial fibrinoid necrosis were occasionally present. Median hepatic Pb concentrations varied from 20 ppm (wet wt) in male red-winged blackbirds to III ppm in female northern bobwhites. Median renal Pb concentrations varied from 22 ppm in red-winged blackbirds to 190 ppm in female northern bobwhites. Hepatic and renal Pb concentrations varied substantially among birds within each species. Median hepatic and renal Pb concentrations of birds that died were not statistically

  13. Glyphosate poisoning.

    Science.gov (United States)

    Bradberry, Sally M; Proudfoot, Alex T; Vale, J Allister

    2004-01-01

    Glyphosate is used extensively as a non-selective herbicide by both professional applicators and consumers and its use is likely to increase further as it is one of the first herbicides against which crops have been genetically modified to increase their tolerance. Commercial glyphosate-based formulations most commonly range from concentrates containing 41% or more glyphosate to 1% glyphosate formulations marketed for domestic use. They generally consist of an aqueous mixture of the isopropylamine (IPA) salt of glyphosate, a surfactant, and various minor components including anti-foaming and colour agents, biocides and inorganic ions to produce pH adjustment. The mechanisms of toxicity of glyphosate formulations are complicated. Not only is glyphosate used as five different salts but commercial formulations of it contain surfactants, which vary in nature and concentration. As a result, human poisoning with this herbicide is not with the active ingredient alone but with complex and variable mixtures. Therefore, It is difficult to separate the toxicity of glyphosate from that of the formulation as a whole or to determine the contribution of surfactants to overall toxicity. Experimental studies suggest that the toxicity of the surfactant, polyoxyethyleneamine (POEA), is greater than the toxicity of glyphosate alone and commercial formulations alone. There is insufficient evidence to conclude that glyphosate preparations containing POEA are more toxic than those containing alternative surfactants. Although surfactants probably contribute to the acute toxicity of glyphosate formulations, the weight of evidence is against surfactants potentiating the toxicity of glyphosate. Accidental ingestion of glyphosate formulations is generally associated with only mild, transient, gastrointestinal features. Most reported cases have followed the deliberate ingestion of the concentrated formulation of Roundup (The use of trade names is for product identification purposes only and

  14. Evaluating controls on the aspect dependence of earthflows in the central California Coast Ranges

    Science.gov (United States)

    Nereson, A. L.; Finnegan, N. J.; Booth, A. M.

    2013-12-01

    Earthflows are an important mass-wasting process in many mountainous landscapes. In addition to radically changing the fabric of the landscape and damaging man-made infrastructure, earthflows deliver, for their area, a disproportionately large sediment load to rivers. In California, earthflows are typically restricted to clay-rich and mechanically-weak lithologies, such as the Franciscan mélange. In addition, several studies have observed that earthflows in California favor south-facing slopes, even in settings with spatially-uniform lithology. This fundamental observation remains largely unexplained under the current understanding of earthflow behavior. Here, we evaluate the controls on the aspect dependence of earthflows in the Alameda Creek watershed near Fremont, California, where many large, but relatively inactive earthflows are observed in the Franciscan mélange. We first apply spectral analysis to LiDAR-derived digital elevation models to objectively map the topographic signature of landslides and determine the degree of aspect dependence. We then explore several hypotheses that can explain our observation that earthflows tend to form on south-facing slopes, including: (1) lack of dense vegetation and trees with slope-stabilizing root systems on south-facing slopes; (2) higher pore fluid pressures due to relatively lower rates of evapotranspiration on sparsely vegetated south-facing slopes; (3) increased dessication and/or deformation cracking on south-facing earthflow surfaces, creating fast-flow pathways into the interior of landslides.

  15. Surveillance, insecticide resistance and control of an invasive Aedes aegypti (Diptera: Culicidae) population in California.

    Science.gov (United States)

    Cornel, Anthony J; Holeman, Jodi; Nieman, Catelyn C; Lee, Yoosook; Smith, Charles; Amorino, Mark; Brisco, Katherine K; Barrera, Roberto; Lanzaro, Gregory C; Mulligan Iii, F Stephen

    2016-01-01

    The invasion and subsequent establishment in California of Aedes aegypti in 2013 has created new challenges for local mosquito abatement and vector control districts. Studies were undertaken to identify effective and economical strategies to monitor the abundance and spread of this mosquito species as well as for its control. Overall, BG Sentinel (BGS) traps were found to be the most sensitive trap type to measure abundance and spread into new locations. Autocidal-Gravid-Ovitraps (AGO-B), when placed at a site for a week, performed equally to BGS in detecting the presence of female Ae. aegypti. Considering operational cost and our findings, we recommend use of BGS traps for surveillance in response to service requests especially in locations outside the known infestation area. We recommend AGO-Bs be placed at fixed sites, cleared and processed once a week to monitor mosquito abundance within a known infestation area. Long-term high density placements of AGO-Bs were found to show promise as an environmentally friendly trap-kill control strategy. California Ae. aegypti were found to be homozygous for the V1016I mutation in the voltage gated sodium channel gene, which is implicated to be involved in insecticide resistance. This strain originating from Clovis, California was resistant to some pyrethroids but not to deltamethrin in bottle bio-assays. Sentinel cage ultra-low-volume (ULV) trials using a new formulation of deltamethrin (DeltaGard®) demonstrated that it provided some control (average of 56% death in sentinel cages in a 91.4 m spray swath) after a single truck mounted aerial ULV application in residential areas.

  16. Surveillance, insecticide resistance and control of an invasive Aedes aegypti (Diptera: Culicidae) population in California

    Science.gov (United States)

    Cornel, Anthony J.; Holeman, Jodi; Nieman, Catelyn C.; Lee, Yoosook; Smith, Charles; Amorino, Mark; Brisco, Katherine K.; Barrera, Roberto; Lanzaro, Gregory C.; Mulligan III, F. Stephen

    2016-01-01

    The invasion and subsequent establishment in California of Aedes aegypti in 2013 has created new challenges for local mosquito abatement and vector control districts. Studies were undertaken to identify effective and economical strategies to monitor the abundance and spread of this mosquito species as well as for its control. Overall, BG Sentinel (BGS) traps were found to be the most sensitive trap type to measure abundance and spread into new locations. Autocidal-Gravid-Ovitraps (AGO-B), when placed at a site for a week, performed equally to BGS in detecting the presence of female Ae. aegypti. Considering operational cost and our findings, we recommend use of BGS traps for surveillance in response to service requests especially in locations outside the known infestation area. We recommend AGO-Bs be placed at fixed sites, cleared and processed once a week to monitor mosquito abundance within a known infestation area. Long-term high density placements of AGO-Bs were found to show promise as an environmentally friendly trap-kill control strategy. California Ae. aegypti were found to be homozygous for the V1016I mutation in the voltage gated sodium channel gene, which is implicated to be involved in insecticide resistance. This strain originating from Clovis, California was resistant to some pyrethroids but not to deltamethrin in bottle bio-assays. Sentinel cage ultra-low-volume (ULV) trials using a new formulation of deltamethrin (DeltaGard®) demonstrated that it provided some control (average of 56% death in sentinel cages in a 91.4 m spray swath) after a single truck mounted aerial ULV application in residential areas. PMID:27158450

  17. 2000-2009年全国职业中毒状况规律分析和对策探讨%Analysis and control proposal of occupational poisoning from 2000 to 2009 in China

    Institute of Scientific and Technical Information of China (English)

    徐桂芹

    2011-01-01

    occupational poisoning accidents was downtrend contrary to that of the chronic occupational poisoning accidents. The former two chemicals caused accurate occupational poisoning accidents were carbon dioxide and hydrogen sulfide.Lead and lead compounds were the former two chemicals caused chronic occupational poisoning accidents. As for occupational poisoning control, it is very important to strengthen the supervision on occupational poisoning, as well as improve training effect.

  18. Oral hyposensitization to poison ivy and poison oak.

    Science.gov (United States)

    Marks, J G; Trautlein, J J; Epstein, W L; Laws, D M; Sicard, G R

    1987-04-01

    We evaluated the safety and efficacy of a 1:1 mixture of pentadecylcatechol (PDC) and heptadecylcatechol (HDC) diacetate in reducing hypersensitivity to poison ivy and poison oak. The study was double-blind, parallel, randomized, and placebo controlled. The 44 subjects receiving the active drug ingested a cumulative dose of 306.5 mg over a five-week period. Subsequently, 14 patients were continued on a maintenance phase, ingesting an additional 960 mg of drug. The PDC-HDC diacetate was well tolerated, with no significant side effects. Evaluation of efficacy compared poststudy and prestudy reactions to patch tests using urushiol in doses of 0.025, 0.05, 0.125, 0.25, and 0.5 micrograms applied to the forearm. The results indicated that the induction phase as well as the maintenance phase did not induce a statistically significant hyposensitivity to urushiol, and we were thus unable to decrease sensitivity to poison ivy and poison oak in humans using orally ingested PDC-HDC diacetate.

  19. Intractable Seizures and Rehabilitation in Ciguatera Poisoning.

    Science.gov (United States)

    Derian, Armen; Khurana, Seema; Rothenberg, Joshua; Plumlee, Charles

    2016-08-31

    Ciguatera fish poisoning is the most frequently reported seafood toxin illness associated with the ingestion of contaminated tropical fish. Diagnosis relies on a history of recent tropical fish ingestion and subsequent development of gastrointestinal, cardiovascular, and neurological symptoms. Ciguatera poisoning usually has a self-limited time course, and its management involves symptomatic control and supportive care. This case report presents an uncommon case of ciguatera poisoning with prolonged intractable seizures refractory to standard antiseizure medications. The patient also had significant functional decline that responded to rigorous inpatient rehabilitation not previously described in literature.

  20. Information Management System for the California State Water Resources Control Board (SWRCB)

    Science.gov (United States)

    Heald, T. C.; Redmann, G. H.

    1973-01-01

    A study was made to establish the requirements for an integrated state-wide information management system for water quality control and water quality rights for the State of California. The data sources and end requirements were analyzed for the data collected and used by the numerous agencies, both State and Federal, as well as the nine Regional Boards under the jurisdiction of the State Board. The report details the data interfaces and outlines the system design. A program plan and statement of work for implementation of the project is included.

  1. Monitoring poison control center data to detect health hazards during hurricane season--Florida, 2003-2005.

    Science.gov (United States)

    2006-04-21

    Eight hurricanes made landfall in Florida from August 13, 2004, through October 24, 2005. Each hurricane caused flooding and widespread power outages. In the fall of 2004, the Florida Department of Health (FDOH) began retrospectively reviewing data collected by the Florida Poison Information Center Network (FPICN) during the 2004 hurricane season. During the 2005 hurricane season, FDOH, in consultation with FPICN, initiated daily monitoring of FPICN records of exposures that might reflect storm-related health hazards. Analysis of these data determined that 28 carbon monoxide (CO) exposures were reported to FPICN in the 2 days after Hurricane Katrina made its August 25, 2005, landfall in Florida, en route to a second landfall on the Gulf Coast. Data on CO and other exposures were used to develop and distribute public health prevention messages to Florida communities affected by hurricanes.

  2. Hair dye poisoning

    Science.gov (United States)

    Hair tint poisoning ... Different types of hair dye contain different harmful ingredients. The harmful ingredients in permanent dyes are: Naphthylamine Other aromatic amino compounds Phenylenediamines Toluene ...

  3. Design issues for the active control system of the California Extremely Large Telescope (CELT)

    Science.gov (United States)

    Chanan, Gary A.; Nelson, Jerry E.; Ohara, Catherine M.; Sirko, Edwin

    2000-08-01

    We explore the issues in the control and alignment of the primary mirror of the proposed 30 meter California Extremely Large Telescope and other very large telescopes with segmented primaries (consisting of 1000 or more segments). We show that as the number of segments increases, the noise in the telescope active control system (ACS) increases, roughly as (root)n. This likely means that, for a thousand segment telescope like CELT, Keck-style capacitive sensors will not be able to adequately monitor the lowest spatial frequency degrees of freedom of the primary mirror, and will therefore have to be supplemented by a Shack-Hartmann-type wavefront sensor. However, in the case of segment phasing, which is governed by a `control matrix' similar to that of the ACS, the corresponding noise is virtually independent of n. It follows that reasonably straightforward extensions of current techniques should be adequate to phase the extremely large telescopes of the future.

  4. Cartap poisoning: A rare case report

    Directory of Open Access Journals (Sweden)

    A S Praveen Kumar

    2011-01-01

    Full Text Available Cartap is a pesticide commonly used to control weevil and caterpillars. It is an analogue of nereistoxin, a neurotoxic substance isolated from the marine annelid Lumbriconereis heteropoda. It causes neuromuscular blockade. Poisoning with cartap is very rare and not yet reported from India. We report a 35-year-old lady with cartap poisoning who presented with nausea, vomiting, and dyspnea. She improved with N-acetyl cysteine and symptomatic management.

  5. Cartap poisoning: A rare case report

    OpenAIRE

    A S Praveen Kumar; Deepak Amalnath; T K Dutta

    2011-01-01

    Cartap is a pesticide commonly used to control weevil and caterpillars. It is an analogue of nereistoxin, a neurotoxic substance isolated from the marine annelid Lumbriconereis heteropoda. It causes neuromuscular blockade. Poisoning with cartap is very rare and not yet reported from India. We report a 35-year-old lady with cartap poisoning who presented with nausea, vomiting, and dyspnea. She improved with N-acetyl cysteine and symptomatic management.

  6. Cartap poisoning: A rare case report.

    Science.gov (United States)

    Kumar, A S Praveen; Amalnath, Deepak; Dutta, T K

    2011-10-01

    Cartap is a pesticide commonly used to control weevil and caterpillars. It is an analogue of nereistoxin, a neurotoxic substance isolated from the marine annelid Lumbriconereis heteropoda. It causes neuromuscular blockade. Poisoning with cartap is very rare and not yet reported from India. We report a 35-year-old lady with cartap poisoning who presented with nausea, vomiting, and dyspnea. She improved with N-acetyl cysteine and symptomatic management.

  7. Suspected poisoning of domestic animals by pesticides.

    Science.gov (United States)

    Caloni, Francesca; Cortinovis, Cristina; Rivolta, Marina; Davanzo, Franca

    2016-01-01

    A retrospective study was carried out by reviewing all suspected cases of domestic animal poisoning attributed to pesticides, reported to the Milan Poison Control Centre (MPCC) between January 2011 and December 2013. During this period, pesticides were found to be responsible for 37.3% of all suspected poisoning enquiries received (815). The most commonly species involved was the dog (71.1% of calls) followed by the cat (15.8%), while a limited number of cases involved horses, goats and sheep. Most cases of exposure (47.1%) resulted in mild to moderate clinical signs. The outcome was reported in 59.9% of these cases, with death occurring in 10.4% of them. Insecticides (40.8%) proved to be the most common group of pesticides involved and exposure to pyrethrins-pyrethroids accounted for the majority of calls. According to the MPCC data, there has been a decrease in the number of suspected poisonings cases attributed to pesticides that have been banned by the EU, including aldicarb, carbofuran, endosulfan and paraquat. In contrast, there has been an increase of suspected poisoning cases attributed to the neonicotinoids, imidacloprid and acetamiprid, probably due to their widespread use in recent years. Cases of suspected poisoning that involved exposure to rodenticides accounted for 27.6% of calls received by the MPCC and anticoagulant rodenticides were the primary cause of calls, with many cases involving brodifacoum and bromadiolone. Herbicides were involved in 14.2% of calls related to pesticides and glyphosate was the main culprit in cases involving dogs, cats, horses, goats and sheep. As far as exposure to molluscicides (11.5%) and fungicides (5.9%), most of the cases involved dogs and the suspected poisoning agents were metaldehyde and copper compounds respectively. The data collected are useful in determining trends in poisoning episodes and identifying newly emerging toxicants, thus demonstrating the prevalence of pesticides as causative agents in animal

  8. Nutrient and temperature controls on modern carbonate production: An example from the Gulf of California, Mexico

    Science.gov (United States)

    Halfar, Jochen; Godinez-Orta, Lucio; Mutti, Maria; Valdez-Holguín, José E.; Borges, Jose M.

    2004-03-01

    In addition to salinity and temperature, nutrient concentrations in surface waters are known to have a significant impact on distribution of carbonate-producing biota, but have never been quantitatively evaluated against different temperatures along a latitudinal transect. The western coast of the Gulf of California, Mexico, presents a natural laboratory for investigating the influence of oceanographic parameters such as salinity, temperature, and chlorophyll a, a proxy for nutrients, on the composition of a range of modern heterozoan and photozoan carbonate environments along a north-south latitudinal gradient spanning the entire warm-temperate realm (29°N 23°N). Chlorophyll a, measured in situ at half-hour resolution, is highly variable throughout the year due to short-term upwelling, and increases significantly from the southern to northern Gulf of California. Salinity, in contrast, fluctuates little and remains at an average of 35‰. From south to north, carbonate production ranges from oligotrophic-mesotrophic, coral reef dominated shallow-water areas (minimum temperature 18.6 °C) through mesotrophic-eutrophic, red algal dominated, inner-shelf carbonate production in the central gulf (minimum temperature 16 °C), and to molluscan-bryozoan, eutrophic inner- to outer-shelf environments (minimum temperature 13.7 °C). The Gulf of California data, supplemented with oceanographic and compositional information from a database compiled from a spectrum of modern carbonate systems worldwide, demonstrates the significance of nutrient control in the formation of heterozoan, photozoan, and transitional heterozoan-photozoan carbonate systems and serves as a basis for more accurately interpreting fossil carbonates.

  9. Challenges with controlling varicella in prison settings: Experience of California, 2010–2011

    Science.gov (United States)

    Leung, Jessica; Lopez, Adriana S.; Tootell, Elena; Baumrind, Nikki; Mohle-Boetani, Janet; Leistikow, Bruce; Harriman, Kathleen H.; Preas, Christopher P.; Cosentino, Giorgio; Bialek, Stephanie R.; Marin, Mona

    2015-01-01

    We describe the epidemiology of varicella in one state prison in California during 2010–2011, control measures implemented, and associated costs. Eleven varicella cases were reported, 9 associated with 2 outbreaks. One outbreak consisted of 3 cases and the second consisted of 6 cases with 2 generations of spread. Among exposed inmates serologically tested, 98% (643/656) were VZV sero-positive. The outbreaks resulted in >1,000 inmates exposed, 444 staff exposures, and >$160,000 in costs. We documented the challenges and costs associated with controlling and managing varicella in a prison setting. A screening policy for evidence of varicella immunity for incoming inmates and staff and vaccination of susceptible persons has the potential to mitigate the impact of future outbreaks and reduce resources necessary for managing cases and outbreaks. PMID:25201912

  10. Challenges with controlling varicella in prison settings: experience of California, 2010 to 2011.

    Science.gov (United States)

    Leung, Jessica; Lopez, Adriana S; Tootell, Elena; Baumrind, Nikki; Mohle-Boetani, Janet; Leistikow, Bruce; Harriman, Kathleen H; Preas, Christopher P; Cosentino, Giorgio; Bialek, Stephanie R; Marin, Mona

    2014-10-01

    This article describes the epidemiology of varicella in one state prison in California during 2010 and 2011, control measures implemented, and associated costs. Eleven varicella cases were reported, of which nine were associated with two outbreaks. One outbreak consisted of three cases and the second consisted of six cases with two generations of spread. Among exposed inmates serologically tested, 98% (643/656) were varicella-zoster virus seropositive. The outbreaks resulted in > 1,000 inmates exposed, 444 staff exposures, and > $160,000 in costs. The authors documented the challenges and costs associated with controlling and managing varicella in a prison setting. A screening policy for evidence of varicella immunity for incoming inmates and staff and vaccination of susceptible persons has the potential to mitigate the impact of future outbreaks and reduce resources necessary to manage cases and outbreaks.

  11. Amnesic Shellfish Poisoning (ASP)

    DEFF Research Database (Denmark)

    Ravn, H.

    HAB Publ. Ser. vol 1 is a supplement to Chapter 7 Mehtods for Domoic Acid, the Amnesic Shellfish Poisons in the IOC Manual of Harmful Marine Microalgae......HAB Publ. Ser. vol 1 is a supplement to Chapter 7 Mehtods for Domoic Acid, the Amnesic Shellfish Poisons in the IOC Manual of Harmful Marine Microalgae...

  12. Cartap Hydrochloride Poisoning.

    Science.gov (United States)

    Kalyaniwala, Kimmin; Abhilash, Kpp; Victor, Peter John

    2016-08-01

    Cartap hydrochloride is a moderately hazardous nereistoxin insecticide that is increasingly used for deliberate self-harm in India. It can cause neuromuscular weakness resulting in respiratory failure. We report a patient with 4% Cartap hydrochloride poisoning who required mechanical ventilation for 36-hours. He recovered without any neurological deficits. We also review literature on Cartap hydrochloride poisoning.

  13. Cyanide poisoning after bitter almond ingestion

    Directory of Open Access Journals (Sweden)

    Y Mouaffak

    2013-01-01

    Full Text Available Plants are responsible for 5% poisoning recorded by Poison Control Centers. Among all known toxic plants, some present a real danger if ingested. We report the case of a five years old child, who presented, after ten bitter almonds ingestion, consciousness disorders progressing to coma with generalized tonic-clonic seizures, miosis and metabolic acidosis. Bitter almonds and nuclei of stone fruits or other rosaceae (apricot, peach, plum contain cyanogenic glycosides, amygdalin, that yields hydrogen cyanide when metabolized in the body. Swallowing six to ten bitter almonds may cause serious poisoning, while the ingestion of fifty could kill a man. The binding of cyanide ions on cytochrome oxidase lead to a non hypoxemic hypoxia by blocking the cellular respiratory chain. Therapeutic measures include, oxygen support, correction of acidosis and cyanide antidote by hydroxocobalamin in case of serious poisoning.

  14. Ecology and control of an introduced population of Southern Watersnakes (Nerodia fasciata) in southern California

    Science.gov (United States)

    Reed, Robert; Todd, Brian D; Miano, Oliver J.; Canfield, Mark; Fisher, Robert N.; McMartin, Louanne

    2016-01-01

    Native to the southeastern United States, Southern Watersnakes (Nerodia fasciata) are known from two sites in California, but their ecological impacts are poorly understood. We investigated the ecology of Southern Watersnakes in Machado Lake, Harbor City, Los Angeles County, California, including an assessment of control opportunities. We captured 306 watersnakes as a result of aquatic trapping and hand captures. We captured snakes of all sizes (162–1063 mm snout–vent length [SVL], 3.5–873.3 g), demonstrating the existence of a well-established population. The smallest reproductive female was 490 mm SVL and females contained 12–46 postovulatory embryos (mean  =  21). Small watersnakes largely consumed introduced Western Mosquitofish (Gambusia affinis), while larger snakes specialized on larval and metamorph American Bullfrogs (Lithobates catesbeianus) and Green Sunfish (Lepomis cyanellus). Overall capture per unit effort (CPUE) in traps declined with time during an intensive 76-d trapping bout, but CPUE trends varied considerably among traplines and it is unlikely that the overall decline in CPUE represented a major decrease in the snake population size. Although we found no direct evidence that Southern Watersnakes are affecting native species in Machado Lake, this population may serve as a source for intentional or unintentional transportation of watersnakes to bodies of water containing imperiled native prey species or potential competitors.

  15. 控制高毒农药在预防农村急性农药中毒中的意义%Effects of controlling specific dangerous pesticides on prevention of acute pesticide poisoning in rural area

    Institute of Scientific and Technical Information of China (English)

    张平; 赵江霞; 常秀丽; 周志俊

    2010-01-01

    Objective To investigate the effects of controlling the specific dangerous pesticides on prevention of acute pesticide poisoning in rural area. Methods The data of reported cases of pesticide poisoning were analyzed to find out the specific dangerous pesticide in acute pesticide poisoning. Then the occurrence of occupational pesticide poisoning and fatality of non-occupational pesticide poisoning were estimated under the hypothesis of removing the specific dangerous pesticides. Results The data indicated that parathion (including methyl parathion) was the specific dangerous pesticide inducing occupational pesticide poisoning.After removing the use of parathion, the hazard of pesticides which caused occupational pesticide poisoning would be significantly decreased(P<0.01 ). Parathion was also the most dangerous pesticide which caused nonoccupational pesticide poisoning, with its fatality up to 15.8%. If parathion was well controlled, the fatality of non-occupational pesticide poisoning would be declined from 9.4% to 7.4%. The analyses of related literatures also revealed the similar results. Conclusion The occurrence of occupational pesticide poisoning and fatality of non-occupational pesticide poisoning may decrease if the most dangerous pesticides are well supervised.%目的 探讨控制危害最大的农药在预防农村急性农药中毒中所起的作用.方法 通过对某省某县医院既往中毒病例的分析,发现在农村中最易发生中毒的特危农药,假设在控制这些农药后,估测生产性农药中毒的发生和非生产性农药中毒病死率的变化趋势.结果 对硫磷(含甲基对硫磷)是某省某县引起生产性农药中毒危害最大的农药,在控制了对硫磷农药的使用之后,生产性农药中毒危害的大小[生产性农药中毒的例数(A)与非生产性农药中毒的例数(B)的比值]由控制前的0.63下降为0.32,差异有统计学意义(P<0.01).对硫磷同样是引起非生产性农药中毒危害

  16. Look Out! It's Poison Ivy!

    Science.gov (United States)

    Darlington, Elizabeth, Day

    1986-01-01

    Provides background information on poison ivy and offers suggestions for instructional activities. Includes illustrations of the varieties of poison ivy leaf forms and poison ivy look-alikes. Highlights interesting facts and cases associated with poison ivy and its relatives. (ML)

  17. Biological and Cultural Control of Olive Fruit Fly in California---Utilization of Parasitoids from USDA-APHIS-PPQ, Guatemala

    Science.gov (United States)

    The parasitoid Psytallia cf. concolor (Szépligeti) was reared on sterile Mediterranean fruit fly larvae at the USDA-APHIS-PPQ, Petapa Quarantine Laboratory in Guatemala and shipped to the USDA-ARS, Parlier, for wide-spread release and biological control of olive fruit fly in California. As many as 3...

  18. Strong top-down control in southern California kelp forest ecosystems.

    Science.gov (United States)

    Halpern, Benjamin S; Cottenie, Karl; Broitman, Bernardo R

    2006-05-26

    Global-scale changes in anthropogenic nutrient input into marine ecosystems via terrestrial runoff, coupled with widespread predator removal via fishing, have created greater urgency for understanding the relative role of top-down versus bottom-up control of food web dynamics. Yet recent large-scale studies of community regulation in marine ecosystems have shown dramatically different results that leave this issue largely unresolved. We combined a multiyear, large-scale data set of species abundances for 46 species in kelp forests from the California Channel Islands with satellite-derived primary production and found that top-down control explains 7- to 10-fold more of the variance in abundance of bottom and mid-trophic levels than does bottom-up control. This top-down control was propagated via a variety of species-level direct and indirect responses to predator abundance. Management of top-down influences such as fishing may be more important in coastal marine ecosystems, particularly in kelp forest systems, than is commonly thought.

  19. Investigation of a staphylococcal food poisoning outbreak combining case-control, traditional typing and whole genome sequencing methods, Luxembourg, June 2014.

    Science.gov (United States)

    Mossong, Joël; Decruyenaere, Frédéric; Moris, Gilbert; Ragimbeau, Catherine; Olinger, Christophe M; Johler, Sophia; Perrin, Monique; Hau, Patrick; Weicherding, Pierre

    2015-01-01

    In June 2014, a staphylococcal food poisoning outbreak occurred at an international equine sports event in Luxembourg requiring the hospitalisation of 31 persons. We conducted a microbiological investigation of patients and buffet items, a case-control study and a carriage study of catering staff. Isolates of Staphylococcus aureus from patients, food and catering staff were characterised and compared using traditional typing methods and whole genome sequencing. Genotypically identical strains (sequence type ST8, spa-type t024, MLVA-type 4698, enterotoxin A FRI100) were isolated in 10 patients, shiitake mushrooms, cured ham, and in three members of staff. The case-control study strongly suggested pasta salad with pesto as the vehicle of infection (p<0.001), but this food item could not be tested, because there were no leftovers. Additional enterotoxigenic strains genetically unrelated to the outbreak strain were found in four members of staff. Non-enterotoxigenic strains with livestock-associated sequence type ST398 were isolated from three food items and two members of staff. The main cause of the outbreak is likely to have been not maintaining the cold chain after food preparation. Whole genome sequencing resulted in phylogenetic clustering which concurred with traditional typing while simultaneously characterising virulence and resistance traits.

  20. The effect of the California tobacco control program on smoking prevalence, cigarette consumption, and healthcare costs: 1989-2008.

    Directory of Open Access Journals (Sweden)

    James Lightwood

    Full Text Available BACKGROUND: Previous research has shown that tobacco control funding in California has reduced per capita cigarette consumption and per capita healthcare expenditures. This paper refines our earlier model by estimating the effect of California tobacco control funding on current smoking prevalence and cigarette consumption per smoker and the effect of prevalence and consumption on per capita healthcare expenditures. The results are used to calculate new estimates of the effect of the California Tobacco Program. METHODOLOGY/PRINCIPAL FINDINGS: Using state-specific aggregate data, current smoking prevalence and cigarette consumption per smoker are modeled as functions of cumulative California and control states' per capita tobacco control funding, cigarette price, and per capita income. Per capita healthcare expenditures are modeled as a function of prevalence of current smoking, cigarette consumption per smoker, and per capita income. One additional dollar of cumulative per capita tobacco control funding is associated with reduction in current smoking prevalence of 0.0497 (SE.00347 percentage points and current smoker cigarette consumption of 1.39 (SE.132 packs per smoker per year. Reductions of one percentage point in current smoking prevalence and one pack smoked per smoker are associated with $35.4 (SE $9.85 and $3.14 (SE.786 reductions in per capita healthcare expenditure, respectively (2010 dollars, using the National Income and Product Accounts (NIPA measure of healthcare spending. CONCLUSIONS/SIGNIFICANCE: Between FY 1989 and 2008 the California Tobacco Program cost $2.4 billion and led to cumulative NIPA healthcare expenditure savings of $134 (SE $30.5 billion.

  1. Potassium carbonate poisoning

    Science.gov (United States)

    Potassium carbonate is a white powder used to make soap, glass, and other items. This article discusses poisoning from swallowing or breathing in potassium carbonate. This article is for information only. Do ...

  2. Sodium hydroxide poisoning

    Science.gov (United States)

    Sodium hydroxide is a very strong chemical. It is also known as lye and caustic soda. This ... poisoning from touching, breathing in (inhaling), or swallowing sodium hydroxide. This article is for information only. Do ...

  3. Sodium carbonate poisoning

    Science.gov (United States)

    Sodium carbonate (known as washing soda or soda ash) is a chemical found in many household and ... products. This article focuses on poisoning due to sodium carbonate. This article is for information only. Do ...

  4. [Suicidal poisoning with benzodiazepines].

    Science.gov (United States)

    Chodorowski, Z; Sein Anand, J

    1997-01-01

    In the period from 1987 to 1996, 103 patients with suicidal benzodiazepines poisoning were treated, including 62 women and 41 men from 16 to 79 (mean 34) years old. 23 persons were poisoned only by benzodiazepines, in 80 remaining cases intoxications were mixed eg. including benzodiazepines and alcohol, tricyclic antidepressants, barbiturates, opioids, phenothiazines. The main causes of suicides were mainly depression, drug addiction and alcoholism. Nobody died in the benzodiazepines group, while mortality rate in the group of mixed poisoning was 4%. Prescribing benzodiazepines by physicians was quite often not justified and facilitated, among others, accumulation of the dose sufficient for suicide attempt. Flumazenil was efficient for leading out from coma in 86% of cases with poisoning only by benzodiazepines and 13% of cases with mixed intoxications mainly containing benzodiazepines and alcohol or carbamazepine.

  5. Hand lotion poisoning

    Science.gov (United States)

    ... lotion or cream can be harmful if swallowed: Dimethicone Mineral oil Paraffins (waxes) Petrolatum Various alcohols Where ... Hand cream poisoning References Caraccio TR, McFee RB. Cosmetics and toilet articles. In: Shannon MW, Borron SW, ...

  6. Swimming pool cleaner poisoning

    Science.gov (United States)

    Swimming pool cleaner poisoning occurs when someone swallows this type of cleaner, touches it, or breathes in ... The harmful substances in swimming pool cleaner are: Bromine ... copper Chlorine Soda ash Sodium bicarbonate Various mild acids

  7. Cedar leaf oil poisoning

    Science.gov (United States)

    Cedar leaf oil is made from some types of cedar trees. Cedar leaf oil poisoning occurs when someone swallows this substance. ... The substance in cedar leaf oil that can be harmful is thujone (a hydrocarbon).

  8. Ethylene glycol poisoning

    Science.gov (United States)

    ... kidneys. The poisoning causes disturbances in the body's chemistry, including metabolic acidosis . The disturbances may be severe enough to cause profound shock , organ failure, and death. As little as 120 milliliters (approximately 4 fluid ...

  9. Carbon monoxide poisoning

    Science.gov (United States)

    ... and smokers. Carbon monoxide can harm a fetus (unborn baby still in the womb). Symptoms of carbon ... symptoms Outlook (Prognosis) Carbon monoxide poisoning can cause death. For those who survive, recovery is slow. How ...

  10. Ciguatera Fish Poisoning

    Science.gov (United States)

    ... debilitating (Miller, 1991). To date there is no antidote or effectivc treatment, so supportive care and medications ... Diagnosis, Management and Treatment, Chemical Structure, and Molecular Mechanism of Action. Additional Resources Ciguatera Fish Poisoning: Treatment, ...

  11. Poison plants (image)

    Science.gov (United States)

    ... by poor circulation, even stress. An example of contact dermatitis is the reaction of a sensitive person's skin to poison ivy, oak or sumac. Contact with these plants, which contain a chemical called ...

  12. Oximes in organophosphorus poisoning

    Directory of Open Access Journals (Sweden)

    Cherian M

    2005-01-01

    Full Text Available Acute organic insecticide poisoning is a major health problem all over the world, particularly in the developing countries, where organophosphates (OPs are the most common suicidal poisons with high morbidity and mortality and account for a large proportion of patients admitted to intensive care units. Other insecticides less commonly used are organocarbamates, organochlorides, and pyrethroids, which are less toxic and are associated with less morbidity and mortality. Patients with poisoning present with a wide spectrum of gastrointestinal, neurological, and cardiac manifestations. A strong clinical suspicion is necessary to make an early diagnosis and to start appropriate therapy. Treatment is primarily supportive and includes decontamination, anticholinergics, protection of the airway, and cardiac and respiratory support. The use of oximes has been controversial and may be associated with higher mortality owing to a higher incidence of type-II paralysis. They may have other toxic side effects. This paper reviews the literature on OP poisoning.

  13. Asphalt cement poisoning

    Science.gov (United States)

    ... petroleum material that hardens when it cools. Asphalt cement poisoning occurs when someone swallows asphalt. If hot ... found in: Road paving materials Roofing materials Tile cements Asphalt may also be used for other purposes.

  14. Bracken fern poisoning

    Science.gov (United States)

    Bracken fern (Pteridium aquilinum) has worldwide distribution and in some areas dominated plant communities replacing desirable forages. Poisoning is identified as enzootic hematuria, bright blindness, and bracken staggers. This chapter reviews updates new information on the plant, the various poi...

  15. Lead Poisoning (For Parents)

    Science.gov (United States)

    ... organs and tissues that need it, thus causing anemia. Most lead ends up in the bone, where it causes ... vomiting or nausea constipation pallor (pale skin) from ... look for lead poisoning or other health problems. Treatment Treatment for ...

  16. Pine oil poisoning

    Science.gov (United States)

    ... K. General approach to the poisoned patient. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ... Mosby; 2013:chap 147. Lee DC. Hydrocarbons. In: Marx J, ed. Rosen's Emergency Medicine: Concepts and Clinical ...

  17. Collaboration with behavioral health care facilities to implement systemwide tobacco control policies--California, 2012.

    Science.gov (United States)

    Gordon, Lauren; Modayil, Mary V; Pavlik, Jim; Morris, Chad D

    2015-02-05

    The California Tobacco Control Program (CTCP) administered 4 regional trainings in 2012 to staffers at CTCP-funded projects, tobacco control coalitions, several county departments of mental health and alcohol and drug, and administrators and providers from behavioral health care facilities. These trainings focused on the special tobacco use cessation needs and opportunities for cessation among persons with mental illness or substance abuse disorders, and they provided information about cessation and smoke-free policies. CTCP surveyed county and private behavioral health care programs to assess their readiness for adopting tobacco control strategies at treatment facilities. Between baseline and follow-up we found a decrease in the proportion of organizations at the precontemplation or contemplation stages of change and twice as many organizations at the action and maintenance stages of change. Significant obstacles remain to implementing policy: many agencies have concerns about going tobacco-free. But significant progress has been made, as evidenced by new policies and a growing number of tobacco-free coalitions consisting of public health agencies, behavioral health care agencies, and local hospitals.

  18. Collaboration With Behavioral Health Care Facilities to Implement Systemwide Tobacco Control Policies — California, 2012

    Science.gov (United States)

    Gordon, Lauren; Modayil, Mary V.; Pavlik, Jim

    2015-01-01

    The California Tobacco Control Program (CTCP) administered 4 regional trainings in 2012 to staffers at CTCP-funded projects, tobacco control coalitions, several county departments of mental health and alcohol and drug, and administrators and providers from behavioral health care facilities. These trainings focused on the special tobacco use cessation needs and opportunities for cessation among persons with mental illness or substance abuse disorders, and they provided information about cessation and smoke-free policies. CTCP surveyed county and private behavioral health care programs to assess their readiness for adopting tobacco control strategies at treatment facilities. Between baseline and follow-up we found a decrease in the proportion of organizations at the precontemplation or contemplation stages of change and twice as many organizations at the action and maintenance stages of change. Significant obstacles remain to implementing policy: many agencies have concerns about going tobacco-free. But significant progress has been made, as evidenced by new policies and a growing number of tobacco-free coalitions consisting of public health agencies, behavioral health care agencies, and local hospitals. PMID:25654218

  19. Occupational lead poisoning

    OpenAIRE

    Ramírez, Augusto V; Médico del Trabajo. American College of Occupational and Environmental Medicine.

    2013-01-01

    Lead, a ubiquitous heavy metal, has been found in places as unlikely as Greenland’s fossil ice. Egyptians and Hebrews used it. In Spain, Phoenicians c. 2000 BC worked ores of lead. At the end of the XX century, occupational lead’s poisoning became a public health problem in developed countries. In non-developed countries occupational lead poisoning is still frequent. Diagnosis is directed to recognize lead existence at the labor environment and good clinical and occupational documentation. Di...

  20. The Disaster, Ecological Distribution and Control of Poisonous Weeds in Natural Grasslands of Xinjiang Uygur Autonomous Region%新疆天然草地毒草灾害分布与防控对策

    Institute of Scientific and Technical Information of China (English)

    严杜建; 周启武; 路浩; 吴晨晨; 赵宝玉; 曹丹丹; 马烽; 刘晓学

    2015-01-01

    some regions, the grassland poisoned has led to the poisonous grass disaster take place frequently, even broke out, which have increased from the basic ecological problem to a social problem, seriously affected the local social stability and grassland ecological security. At present, more than 85% available natural grasslands are degenerating to a greater or lesser extent and 37.50% of them are severely degraded, with an poisonous weeds disaster area of nearly 700 million hm2, which has accounted for 20.42% of the total hazard area of natural grassland of the country, and the annual death number of animals with poisoning is more than 3000 in average . Xinjiang natural grassland contains common poisonous plants of 81 species, 24 families and 54 genera. Among them, theAconitum carmichaeli, Aconitum soongaricum, Achnatherum inebrians, Oxytropis glabra, Astragalus variabilis, Anabasis aphylla, Pedicularis, Ligularia sibirica andCucuta virosa are more serious harmful poisonous weeds to grassland animal husbandry, which accounted for approximately more than 80% of the total poisonous weeds hazard area. Therefore, a comprehensive understanding of poisonous weeds disaster situation in natural grassland of Xinjiang, weed species and geographic distribution, the effective prevention and control, the solution of the poisonous weeds disaster, is of great significance to improve the grassland productivity and forage quality, promote the sustainable development of animal husbandry in pastoral areas and farmers’ income, flourishing frontier minority economy and stabilize the ecological environment balance. According to the analysis and summary of data reported and results of the project group actually investigated in Xinjiang natural grasslands, the disaster situation, species of poisonous weeds and geographical distribution, prevention and control measures and reasonable utilization are reviewed. The disaster condition of regional grassland ecological and animal husbandry

  1. Poison Center Data for Public Health Surveillance: Poison Center and Public Health Perspectives

    Science.gov (United States)

    Law, Royal K.; Schier, Josh; Schauben, Jay; Wheeler, Katherine; Mulay, Prakash

    2013-01-01

    Objective To describe the use of poison center data for public health surveillance from the poison center, local, state, and federal public health perspectives and to generate meaningful discussion on how to address the challenges to collaboration. Introduction Since 2008, poisoning has become the leading cause of injury-related death in the United States (US); since 1980, the poisoning-related fatality rate in the US has almost tripled.1 Many poison-related injuries and deaths are reported to regional poison centers (PCs) which receive about 2.4 million reports of human chemical and poison exposures annually.2 Federal, state, and local public health (PH) agencies often collaborate with poison centers and use PC data for public health surveillance of poisoning-related health issues. Many state and local PH agencies have partnerships with regional PCs for direct access to local PC data which help them perform this function. At the national level, CDC conducts public health surveillance for exposures and illnesses of public health significance using the National Poison Data System (NPDS), the national PC reporting database. Though most PC and PH officials agree that PC data play an important role in PH practice and surveillance, collaboration between PH agencies and PCs has been hindered by numerous challenges. To address these challenges and bolster collaboration, the Poison Center and Public Health Collaborations Community of Practice (CoP) was created in 2010 by CDC as a means to share experiences, identify best practices, and facilitate relationships among federal, state and local public health agencies and PCs. To date, the Poison Center and Public Health Collaborations CoP includes over 200 members from state and local public health, regional PCs, CDC, the American Association of Poison Control Centers (AAPCC), and the Environmental Protection Agency (EPA). A leadership team was created with representatives of the many stakeholders of the community to drive its

  2. Risk factors for acute pesticide poisoning in Sri Lanka

    DEFF Research Database (Denmark)

    van der Hoek, Wim; Konradsen, Flemming

    2005-01-01

    -poisoning. Case fatality was 18% with extremely high case fatality for poisoning with the insecticide endosulfan and the herbicide paraquat. Cases were generally younger than controls, of lower educational status and were more often unemployed. No agricultural risk factors were found but a family history...

  3. 77 FR 20388 - California State Nonroad Engine Pollution Control Standards; Large Spark-Ignition (LSI) Engines...

    Science.gov (United States)

    2012-04-04

    ... America (``A4A''). A4A comments that California's LSI regulations as applicable to airport ground support.... Other Issues Airlines for America (``A4A'') has provided comments opposing EPA's grant of authorization for California's LSI regulations. The reasons A4A provides in its comments are outside the scope...

  4. Acute Poisoning in Elderly; a Five-Year Study (2008-2013 in Hamadan, Iran

    Directory of Open Access Journals (Sweden)

    Saeed Afzali

    2015-12-01

    Conclusion: Deliberate self-harm and poisoning with opioids especially methadone showed a high prevalence in elderly poisoned patients in Hamadan, Iran.  It seems that drug trafficking control, addiction rehabilitation therapies and suicide prevention programs for elderly can be helpful in poisoning reduction in this age group in this part of the country.

  5. Evaluation of animal control measures on pet demographics in Santa Clara County, California, 1993–2006

    Directory of Open Access Journals (Sweden)

    Philip H. Kass

    2013-02-01

    Full Text Available The measurable benefits of animal control programs are unknown and the aim of this study was to determine the impact of these programs on pet population changes. A prospective cross-sectional study of 1000 households was implemented in 2005 to evaluate characteristics of the owned and unowned population of dogs and cats in Santa Clara County, California. The same population was previously studied 12 years earlier. During this time period, the county instituted in 1994 and then subsequently disestablished a municipal spay/neuter voucher program for cats. Dog intakes declined from 1992–2005, as they similarly did for an adjacent county (San Mateo. However, cat intakes declined significantly more in Santa Clara County than San Mateo, with an average annual decline of approximately 700 cats for the 12 year period. Time series analysis showed a greater than expected decline in the number of cats surrendered to shelters in Santa Clara County during the years the voucher program was in effect (1994–2005. The net savings to the county by reducing the number of cat shelter intakes was estimated at approximately $1.5 million. The measurable benefits of animal control programs are unknown and the aim of this study was to determine the impact of these programs on pet population changes.

  6. Evaluation of animal control measures on pet demographics in Santa Clara County, California, 1993-2006.

    Science.gov (United States)

    Kass, Philip H; Johnson, Karen L; Weng, Hsin-Yi

    2013-01-01

    The measurable benefits of animal control programs are unknown and the aim of this study was to determine the impact of these programs on pet population changes. A prospective cross-sectional study of 1000 households was implemented in 2005 to evaluate characteristics of the owned and unowned population of dogs and cats in Santa Clara County, California. The same population was previously studied 12 years earlier. During this time period, the county instituted in 1994 and then subsequently disestablished a municipal spay/neuter voucher program for cats. Dog intakes declined from 1992-2005, as they similarly did for an adjacent county (San Mateo). However, cat intakes declined significantly more in Santa Clara County than San Mateo, with an average annual decline of approximately 700 cats for the 12 year period. Time series analysis showed a greater than expected decline in the number of cats surrendered to shelters in Santa Clara County during the years the voucher program was in effect (1994-2005). The net savings to the county by reducing the number of cat shelter intakes was estimated at approximately $1.5 million. The measurable benefits of animal control programs are unknown and the aim of this study was to determine the impact of these programs on pet population changes.

  7. Accidental dapsone poisoning in children.

    Science.gov (United States)

    Nair, P M; Philip, E

    1984-12-01

    Accidental poisoning in children shows a trend towards poisoning with various newer drugs and chemicals used in the household. Sixty-one cases of accidental poisoning in children were seen in Sree Avittam Thirunal Hospital, (S.A.T.H.), Trivandrum, South India during the year 1982, constituting 0.61% of the total pediatric admissions. Dapsone poisoning constituted 9.8% of the total accidental poisonings, emphasising the need for safe storage of drugs out of the reach of young children. Dapsone poisoning with resultant methaemoglobinaemia responded well to intravenous ascorbic acid and other supportive measures.

  8. A Tale of two Systems: Poisoning Management in Iran and the United States

    Directory of Open Access Journals (Sweden)

    Omid Mehrpour

    2013-05-01

    Full Text Available Poisoning morbidity and mortality is high in the developing world. Systems for care of poisoned patients differ markedly between countries. In this paper a comparison of two very different systems for the care of poisoned patients, is presented. Specifically, the role of poison centers and poison treatment centers in the US and Iran are contrasted. A systematic literature search was undertaken utilizing the PubMed, Scopus, and Google Scholar and the keywords “poison centers”, “treatment” “Iran” “United States of America” and 100 publications were identified. From these, relevant data were found in 23 publications. The information was double-checked and data were summarized herein.We find that the system of the care of poisoned patients relies heavily on certified poison centers in the US and that only a few hospitals have well developed medical toxicology services. In contrast, in Iran, the poison center system is somehow less developed and the care of poisoned patients is provided in centralized high volume hospital poison units.Although both the US and Iran have highly developed systems for the care of poisoned patients they are distinctly different. Comparative studies based on these systems could provide important data for developing countries with more rudimentary poison control and treatment facilities.

  9. Treatment of severe chloroquine poisoning.

    Science.gov (United States)

    Riou, B; Barriot, P; Rimailho, A; Baud, F J

    1988-01-07

    No therapy has been proved to be effective for patients with severe chloroquine poisoning, which is usually fatal. In a retrospective study of 51 cases, we found that ingestion of more than 5 g of chloroquine was an accurate predictor of a fatal outcome, and therefore chose this dose as the criterion for severe chloroquine poisoning. We selected as a control group 11 consecutive patients who had ingested more than 5 g of chloroquine between July 1983 and December 1985. We then undertook a prospective study to determine whether a better outcome could be obtained with immediate mechanical ventilation and the administration of diazepam and epinephrine. Eleven consecutive patients who ingested more than 5 g of chloroquine in 1986 received this combination therapy. Ten of these patients survived, whereas only one control had survived (P = 0.0003). There was no significant difference between the combination-therapy and control groups in age (29 +/- 3 vs. 27 +/- 2 years), amount of chloroquine ingested (7.5 +/- 0.5 vs. 8.5 +/- 0.8 g), systolic arterial pressure (74 +/- 2 vs. 74 +/- 3 mm Hg), or QRS duration (0.14 +/- 0.01 vs. 0.14 +/- 0.01 second). In our combination-therapy group, blood chloroquine levels ranged from 40 to 80 mumol per liter, whereas a literature search showed that no patient in whom blood levels were more than 25 mumol per liter had survived. These preliminary data suggest that combining early mechanical ventilation with the administration of diazepam and epinephrine may be effective in the treatment of severe chloroquine poisoning.

  10. A review of 29 incidents involving 4-aminopyridine in non-target species reported to the ASPCA Animal Poison Control Center.

    Science.gov (United States)

    McLean, Mary Kay; Khan, Safdar

    2013-12-01

    4-Aminopyridine (4-AP) is an avicide used in products that are approved by the Environmental Protection Agency (EPA) to control populations of various birds. Pharmaceutical 4-AP is also used in humans to treat neural and muscular dysfunctions associated with multiple sclerosis. Although strict restrictions for its use are in place, exposures to 4-AP bait by non-target species still occur. Twenty-nine exposures of 4-AP bait involving non-target species were identified and retrieved from the ASPCA Animal Poison Control Center medical record database. Canines were the most commonly exposed (86 %) species followed by felines (10 %). The highest frequency of exposures was reported from Colorado (22 %). Most commonly reported clinical signs in canines were tremors, hypersalivation, seizures, tachycardia, and ataxia. The onset time of signs ranged from 5 to 300 min with an average of 89 min. Clinical signs lasted from 15 to 84 h with an average of 37 h. Patient outcome was known in six cases; one dog died 4 h after the exposure and five made full recovery with supportive care. Treatment of five surviving patients included administration of activated charcoal, use of anticonvulsants and muscle relaxants like diazepam and methocarbamol, and intravenous fluids. Diagnosis of 4-AP toxicosis can be supported by testing the gastric contents of the exposed patient. Due to the rapid absorption, samples need to be collected and frozen/chilled promptly. For successful patient outcome, treatment must be implemented quickly after an exposure.

  11. Oil-based paint poisoning

    Science.gov (United States)

    Paint - oil based - poisoning ... Hydrocarbons are the primary poisonous ingredient in oil paints. Some oil paints have heavy metals such as lead, mercury, cobalt, and barium added as pigment. These heavy metals can cause additional ...

  12. Poison ivy - oak - sumac rash

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000027.htm Poison ivy - oak - sumac rash To use the sharing features on this page, please enable JavaScript. Poison ivy, oak, and sumac are plants that commonly ...

  13. Case-control study of arsenic in drinking water and lung cancer in California and Nevada.

    Science.gov (United States)

    Dauphiné, David C; Smith, Allan H; Yuan, Yan; Balmes, John R; Bates, Michael N; Steinmaus, Craig

    2013-08-02

    Millions of people are exposed to arsenic in drinking water, which at high concentrations is known to cause lung cancer in humans. At lower concentrations, the risks are unknown. We enrolled 196 lung cancer cases and 359 controls matched on age and gender from western Nevada and Kings County, California in 2002-2005. After adjusting for age, sex, education, smoking and occupational exposures, odds ratios for arsenic concentrations ≥85 µg/L (median = 110 µg/L, mean = 173 µg/L, maximum = 1,460 µg/L) more than 40 years before enrollment were 1.39 (95% CI = 0.55-3.53) in all subjects and 1.61 (95% CI = 0.59-4.38) in smokers. Although odds ratios were greater than 1.0, these increases may have been due to chance given the small number of subjects exposed more than 40 years before enrollment. This study, designed before research in Chile suggested arsenic-related cancer latencies of 40 years or more, illustrates the enormous sample sizes needed to identify arsenic-related health effects in low-exposure countries with mobile populations like the U.S. Nonetheless, our findings suggest that concentrations near 100 µg/L are not associated with markedly high relative risks.

  14. 76 FR 77521 - California State Nonroad Engine Pollution Control Standards; Commercial Harbor Craft Regulations...

    Science.gov (United States)

    2011-12-13

    ... increased risk of burn or fire) associated with compliance with the California standard. \\13\\ See 59 FR... technologically feasible'' because they mirror requirements that EPA has already adopted and determined...

  15. The Management of Food Poisoning in China

    Institute of Scientific and Technical Information of China (English)

    LiTai-ran

    2001-01-01

    This article introduced the characteristics of food poisoning management in China.Food borne diseases are managed in two separate parts by the Ministry of Health in China,Based on different but related laws.Sporadic occurrence of food-borne diseases such as diarrhea,typhoid and dysentery are managed by the "Infectious Diseases Prevention and Control Law" ,while food poisoning outbreaks are managed by the "Food Hygiene Law".Some advantages and disadvantages of this management system will be discussed in the presentation.

  16. The EXTRIP (EXtracorporeal TReatments In Poisoning) workgroup

    DEFF Research Database (Denmark)

    Lavergne, Valéry; Nolin, Thomas D; Hoffman, Robert S

    2012-01-01

    Extracorporeal treatments (ECTRs), such as hemodialysis and hemoperfusion, are used in poisoning despite a lack of controlled human trials demonstrating efficacy. To provide uniform recommendations, the EXTRIP group was formed as an international collaboration among recognized experts from nephro...... of recommendation. This approach will permit the production of the first important practice guidelines on this topic....... nephrology, clinical toxicology, critical care, or pharmacology and supported by over 30 professional societies. For every poison, the clinical benefit of ECTR is weighed against associated complications, alternative therapies, and costs. Rigorous methodology, using the AGREE instrument, was developed...... to retrieve all original publications regardless of language. Data were extracted on a standardized instrument. Quality of the evidence was assessed by GRADE as: High = A, Moderate = B, Low = C, Very Low = D. For every poison, dialyzability was assessed and clinical effect of ECTR summarized. All pertinent...

  17. Poison Ivy/Oak/Sumac

    Science.gov (United States)

    ... Your 1- to 2-Year-Old First Aid: Poison Ivy/Oak/Sumac KidsHealth > For Parents > First Aid: Poison Ivy/Oak/Sumac Print A A A The oil in poison ivy /oak/sumac plants (called urushiol ) can cause ...

  18. Black-spot poison ivy.

    Science.gov (United States)

    Schram, Sarah E; Willey, Andrea; Lee, Peter K; Bohjanen, Kimberly A; Warshaw, Erin M

    2008-01-01

    In black-spot poison ivy dermatitis, a black lacquerlike substance forms on the skin when poison ivy resin is exposed to air. Although the Toxicodendron group of plants is estimated to be the most common cause of allergic contact dermatitis in the United States, black-spot poison ivy dermatitis is relatively rare.

  19. Cow dung powder poisoning

    Directory of Open Access Journals (Sweden)

    Khaja Mohideen Sherfudeen

    2015-01-01

    Full Text Available Cow dung, which has germicidal property, was used in ancient days to clean living premises in South India. Nowadays, people are using commercially available synthetic cow dung powder. It is locally known as "saani powder" in Tamil Nadu. It is freely available in homes and is sometimes accidentally consumed by children. It is available in two colors - yellow and green. Cow dung powder poisoning is common in districts of Tamil Nadu such as Coimbatore, Tirupur, and Erode. We report two cases of yellow cow dung powder poisoning from our hospital.

  20. Protect the Ones You Love From Poisoning

    Centers for Disease Control (CDC) Podcasts

    2008-12-10

    This podcast, developed as part of the Protect the Ones You Love initiative, discusses steps parents can take to help protect their children from poisoning, one of the leading causes of child injury.  Created: 12/10/2008 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 12/10/2008.

  1. Lead Poisoning in Wild Birds

    Science.gov (United States)

    Lahner, Lesanna L.; Franson, J. Christian

    2009-01-01

    Lead in its various forms has been used for thousands of years, originally in cooking utensils and glazes and more recently in many industrial and commercial applications. However, lead is a potent, potentially deadly toxin that damages many organs in the body and can affect all animals, including humans. By the mid 1990s, lead had been removed from many products in the United States, such as paint and fuel, but it is still commonly used in ammunition for hunting upland game birds, small mammals, and large game animals, as well as in fishing tackle. Wild birds, such as mourning doves, bald eagles, California condors, and loons, can die from the ingestion of one lead shot, bullet fragment, or sinker. According to a recent study on loon mortality, nearly half of adult loons found sick or dead during the breeding season in New England were diagnosed with confirmed or suspected lead poisoning from ingestion of lead fishing weights. Recent regulations in some states have restricted the use of lead ammunition on certain upland game hunting areas, as well as lead fishing tackle in areas frequented by common loons and trumpeter swans. A variety of alternatives to lead are available for use in hunting, shooting sports, and fishing activities.

  2. Complexity in Climatic Controls on Plant Species Distribution: Satellite Data Reveal Unique Climate for Giant Sequoia in the California Sierra Nevada

    OpenAIRE

    Waller, Eric Kindseth

    2014-01-01

    ABSTRACTComplexity in Climatic Controls on Plant Species Distribution: Satellite Data Reveal Unique Climate for Giant Sequoia in the California Sierra NevadabyEric Kindseth WallerDoctor of Philosophy in Environmental Science, Policy, and ManagementUniversity of California, BerkeleyProfessor Dennis D. Baldocchi, ChairA better understanding of the environmental controls on current plant species distribution is essential if the impacts of such diverse challenges as invasive species, changing fir...

  3. Chelation Therapy for Mercury Poisoning

    Directory of Open Access Journals (Sweden)

    Rong Guan

    2009-01-01

    Full Text Available Chelation therapy has been the major treatment for heavy metal poisoning. Various chelating agents have been developed and tested for treatment of heavy metal intoxications, including mercury poisoning. It has been clearly shown that chelating agents could rescue the toxicity caused by heavy metal intoxication, but the potential preventive role of chelating agents against heavy metal poisoning has not been explored much. Recent paper by Siddiqi and colleagues has suggested a protective role of chelating agents against mercury poisoning, which provides a promising research direction for broader application of chelation therapy in prevention and treatment of mercury poisoning.

  4. Congenital abnormalities in methylmercury poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Gilani, S.H.

    1975-04-01

    This study was undertaken to determine the teratogenic potential of methylmercury on chick embryogenesis. Methylmercuric chloride was dissolved in sodium bicarbonate (0.2%) and administered to the chick embryos at doses ranging from 0.0009 to 0.010 mg per egg. The injections were made at days 2 and 3 on incubation (Groups A and B). All the embryos including controls were examined on the 7th day of incubation. Methylmercury poisoning was observed to be both embryolethal and teratogenic. Within the two groups, embryolethality was higher in Group A. The following congenital abnormalities were observed: exencephaly, shortened and twisted limbs, microphthalmia, shortened and twisted neck, beak abnormalities, everted viscera, reduced body size and hemorrhage all over the body. Exencephaly and limb abnormalities were very common. No differences in the incidence and types of gross abnormalities within both the groups (A and B) were noted. The incidence of malformations among the controls was low. The results of present investigation show that methylmercury poisoning is both embryolethal and teratogenic to early chick embryogenesis. (auth)

  5. Outdoor Hazards & Preventive Measures: West Nile Virus: A Clinical Commentary for the Camp Health Care Community; Poison Ivy: A Primer for Prevention; Lyme Disease Prevention and Control.

    Science.gov (United States)

    Reynolds, Ellen; Bauer, Holly; Ratner-Connolly, Heidi

    2003-01-01

    Transmitted by mosquitos, West Nile virus may cause serious illness, but the actual likelihood of infection is low. Prevention, implications, and recommendations for camps are discussed. Poison ivy identification, treatment, and complications are presented; a prevention quiz is included. Signs and symptoms of Lyme disease are described, as are…

  6. 广西2007~2011年有毒动植物食物中毒现状分析%Food poisoning due to toxic plant and control measures

    Institute of Scientific and Technical Information of China (English)

    蒋玉艳; 唐振柱; 刘展华; 黄立嵘; 姚雪婷

    2012-01-01

    Objective To analyze the epidemiological characteristics of toxic plant food poisoning events in Guangxi from 2007 to 2011 so as to provide evidences for the prevention and control of food poisoning. Methods The data of toxic plant food poisoning events in Guangxi reported on network system of China sudden public health events were collected and analyzed. Results There were 64 toxic plant food poisoning events in Guangxi from 2007 to 2011, resulting in 805 persons involved and 43 persons died with the average of 12.58 people per case. The peak season occurred mainly in Autumn. Place distribution of food poisoning events were at family (46.88%) and cafeterias (31.25%). There were largest number of food poisoning at the cafeterias (60.37%); however, the highest mortality was at families (88.37%) with the fatality of 31.40%. The main fatal foods were poisonous mushrooms, fake wine, wild honey and improper processing of kidney bean were Conclusion Health education on the knowledge related to the prevention of toxic plant food poisoning be strengthened.%目的 分析广西有毒动植物食物中毒事件流行病学特征,为预防和控制有毒动植物食物中毒的发生提供科学依据.方法 收集广西2007~ 2011年中国突发公共卫生事件报告管理信息系统上报的有毒动植物食物中毒档案资料,建立数据库,归类统计分析.结果 2007~ 2011年广西共发生有毒动植物食物中毒事件64起,中毒人数805人,死亡43人,平均中毒规模为12.58人/起;中毒高发季节为第3季度;中毒场所主要发生在家庭占46.88%,其次是集体食堂占31.25%;中毒人数以集体食堂为最高,占60.37%,而死亡人数以家庭最高,占88.37%,病死率达31.40%.致死人数较多的因素主要为误食毒蘑菇、自制药酒、野生蜂蜜及菜豆加工不当等.结论 加强预防食物中毒宣教工作将有效控制误食有毒动植物中毒死亡事件的发生.

  7. [Acute arsenic poisoning].

    Science.gov (United States)

    Montelescaut, Etienne; Vermeersch, Véronique; Commandeur, Diane; Huynh, Sophie; Danguy des Deserts, Marc; Sapin, Jeanne; Ould-Ahmed, Mehdi; Drouillard, Isabelle

    2014-01-01

    Acute arsenic poisoning is a rare cause of suicide attempt. It causes a multiple organs failure caused by cardiogenic shock. We report the case of a patient admitted twelve hours after an ingestion of trioxide arsenic having survived thanks to a premature treatment.

  8. Psyttalia cf. concolor (Hymenoptera: Braconidae) for biological control of olive fruit fly (Diptera: Tephritidae) in California.

    Science.gov (United States)

    Yokoyama, Victoria Y; Rendón, Pedro A; Sivinski, John

    2008-06-01

    The larval parasitoid, Psyttalia cf. concolor (Szépligeti), reared on Mediterranean fruit fly, Ceratitis capitata (Weidemann), by the USDA-APHIS-PPQ, Guatemala City, Guatemala, was imported into California for biological control of olive fruit fly, Bactrocera oleae (Gmelin), in olives, Olea europaea L. Mean percentage parasitism of olive fruit fly third instars infesting fruit in field cages ranged from 7.0 in Grapevine to 59.7 in Santa Barbara and in free releases ranged from 0 in Grapevine to 10.6 in Santa Barbara after 4- to 6-d exposures. In the laboratory, more parasitoids developed to adults in olive fruit fly larvae that were 11-13 d old than in larvae 8-10 d old. Adult parasitoids lived significantly longer when provided with water than adults without water in environmental chambers at 5 degrees C, 85% RH; 15 degrees C, 65% RH; 25 degrees C, 25% RH; and 35 degrees C, 25% RH. Adult parasitoids lived for 48 d with honey for food and water and 32 d with food and sugar solution at 15 degrees C and 65% RH. Survival of adult parasitoids without food and water in greenhouse tests was approximately 4 d in a simulated coastal climate and 1 d in a simulated inland valley climate and was significantly increased by providing food and water. The parasitoid did not develop in the beneficial seedhead fly, Chaetorellia succinea (Costa), in yellow star thistle. The rate of parasitism of walnut husk fly, Rhagoletis completa Cresson, larvae in green walnut husks was 28.4% in laboratory no-choice tests. In choice tests, the rate of parasitism of walnut husk fly versus olive fruit fly larvae in olives was 11.5 and 24.2%, respectively.

  9. Use of Sediment Budgets for Watershed Erosion Control Planning: A Case Study From Northern California

    Science.gov (United States)

    O'Connor, M.; McDavitt, W.

    2002-05-01

    Erosion, sedimentation and peak flow increases caused by forest management for commercial timber production may negatively affect aquatic habitat of endangered anadromous fish such as coho salmon ({\\ it O. kisutch}). This paper summarizes a portion of a Watershed Analysis study performed for Pacific Lumber Company, Scotia, CA, focusing on erosion and sedimentation processes and rates and downstream sediment routing and water quality in the Freshwater Creek watershed in northwest California. Hillslope, road and bank erosion, channel sedimentation and sediment rates were quantified using field surveys, aerial photo interpretation, and empirical modeling approaches for different elements of the study. Sediment transport rates for bedload were modeled, and sediment transport rates for suspended sediment were estimated based on size distribution of sediment inputs in relation to sizes transported in suspension. The resulting sediment budget was validated through comparison using recent short-term, high-quality estimates of suspended sediment yield collected by a community watershed group at a downstream monitoring site with technical assistance from the US Forest Service. Another check on the sediment budget was provided by bedload yield data from an adjacent watershed, Jacoby Creek. The sediment budget techniques and bedload routing models used for this study provide sediment yield estimates that are in good agreement with available data. These results suggest that sediment budget techniques that require moderate levels of fieldwork can be used to provide relatively accurate technical assessments for use in the TMDL process. The sediment budget also identifies the most significant sediment sources and suggests a framework within which effective erosion control strategies can be developed.

  10. Using Poison Center Data for Postdisaster Surveillance

    Science.gov (United States)

    Wolkin, Amy; Schnall, Amy H.; Law, Royal; Schier, Joshua

    2015-01-01

    The role of public health surveillance in disaster response continues to expand as timely, accurate information is needed to mitigate the impact of disasters. Health surveillance after a disaster involves the rapid assessment of the distribution and determinants of disaster-related deaths, illnesses, and injuries in the affected population. Public health disaster surveillance is one mechanism that can provide information to identify health problems faced by the affected population, establish priorities for decision makers, and target interventions to meet specific needs. Public health surveillance traditionally relies on a wide variety of data sources and methods. Poison center (PC) data can serve as data sources of chemical exposures and poisonings during a disaster. In the US, a system of 57 regional PCs serves the entire population. Poison centers respond to poison-related questions from the public, health care professionals, and public health agencies. The Centers for Disease Control and Prevention (CDC) uses PC data during disasters for surveillance of disaster-related toxic exposures and associated illnesses to enhance situational awareness during disaster response and recovery. Poison center data can also be leveraged during a disaster by local and state public health to supplement existing surveillance systems. Augmenting traditional surveillance data (ie, emergency room visits and death records) with other data sources, such as PCs, allows for better characterization of disaster-related morbidity and mortality. Poison center data can be used during a disaster to detect outbreaks, monitor trends, track particular exposures, and characterize the epidemiology of the event. This timely and accurate information can be used to inform public health decision making during a disaster and mitigate future disaster-related morbidity and mortality. PMID:25205009

  11. Benzodiazepine poisoning in elderly

    Directory of Open Access Journals (Sweden)

    Perković-Vukčević Nataša

    2016-01-01

    Full Text Available Background/Aim. Benzodiazepines are among the most frequently ingested drugs in self-poisonings. Elderly may be at greater risk compared with younger individuals due to impaired metabolism and increased sensitivity to benzodiazepines. The aim of this study was to assess toxicity of benzodiazepines in elderly attempted suicide. Methods. A retrospective study of consecutive presentations to hospital after self-poisoning with benzodiazepines was done. Collected data consisted of patient's characteristics (age, gender, benzodiazepine ingested with its blood concentrations at admission, clinical findings including vital signs and Glasgow coma score, routine blood chemistry, complications of poisoning, details of management, length of hospital stay and outcome. According the age, patients are classified as young (15-40-year old, middle aged (41-65-year old and elderly (older than 65. Results. During a 2-year observational period 387 patients were admitted because of pure benzodiazepine poisoning. The most frequently ingested drug was bromazepam, the second was diazepam. The incidence of coma was significantly higher, and the length of hospital stay significantly longer in elderly. Respiratory failure and aspiration pneumonia occurred more frequently in old age. Also, flumazenil was more frequently required in the group of elderly patients. Conclusion. Massive benzodiazepines overdose in elderly may be associated with a significant morbidity, including deep coma with aspiration pneumonia, respiratory failure, and even death. Flumazenil is indicated more often to reduce CNS depression and prevent complications of prolonged unconsciousness, but supportive treatment and proper airway management of comatose patients is the mainstay of the treatment of acute benzodiazepine poisoning.

  12. Poisonous or non-poisonous plants? DNA-based tools and applications for accurate identification.

    Science.gov (United States)

    Mezzasalma, Valerio; Ganopoulos, Ioannis; Galimberti, Andrea; Cornara, Laura; Ferri, Emanuele; Labra, Massimo

    2017-01-01

    Plant exposures are among the most frequently reported cases to poison control centres worldwide. This is a growing condition due to recent societal trends oriented towards the consumption of wild plants as food, cosmetics, or medicine. At least three general causes of plant poisoning can be identified: plant misidentification, introduction of new plant-based supplements and medicines with no controls about their safety, and the lack of regulation for the trading of herbal and phytochemical products. Moreover, an efficient screening for the occurrence of plants poisonous to humans is also desirable at the different stages of the food supply chain: from the raw material to the final transformed product. A rapid diagnosis of intoxication cases is necessary in order to provide the most reliable treatment. However, a precise taxonomic characterization of the ingested species is often challenging. In this review, we provide an overview of the emerging DNA-based tools and technologies to address the issue of poisonous plant identification. Specifically, classic DNA barcoding and its applications using High Resolution Melting (Bar-HRM) ensure high universality and rapid response respectively, whereas High Throughput Sequencing techniques (HTS) provide a complete characterization of plant residues in complex matrices. The pros and cons of each approach have been evaluated with the final aim of proposing a general user's guide to molecular identification directed to different stakeholder categories interested in the diagnostics of poisonous plants.

  13. 75 FR 43975 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Truck Idling...

    Science.gov (United States)

    2010-07-27

    ... to fuel-fired heaters, batteries, fuel cells, and power inverter/chargers for on-shore power are not... requirements pertaining to fuel- fired heaters, batteries, fuel cells, power inverter/chargers for on- shore... applicable California off-road or Federal nonroad emission standards and test procedures for its fuel...

  14. 77 FR 9239 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Truck Idling...

    Science.gov (United States)

    2012-02-16

    ... to fuel-fired heaters, batteries, fuel cells, and power inverter/chargers for on-shore power are not... requirements pertaining to fuel- fired heaters, batteries, fuel cells, power inverter/chargers for on- shore... applicable California off-road or federal nonroad emission standards and test procedures for its fuel...

  15. 78 FR 58089 - California State Nonroad Engine Pollution Control Standards; Off-Road Compression Ignition...

    Science.gov (United States)

    2013-09-20

    ... Conditions? a. California Air Quality Today and Moving Forward b. PM Health Effects c. Additional PM Comments... poverty or lack of employment is much stronger than the correlation between poor health and air pollution... applicable Federal requirements in the sense that it may result in some further reduction in air pollution...

  16. Controlled Confrontation: The Ward Grievance Procedure of the California Youth Authority. An Exemplary Project.

    Science.gov (United States)

    National Inst. of Law Enforcement and Criminal Justice (Dept. of Justice/LEAA), Washington, DC.

    The Ward Grievance Procedure of the California Youth Authority is one of 17 programs that earned the National Institute's "Exemplary" label. This brochure provides the requisite practical information for those who wish to test or consider testing the ward grievance procedure. The program was developed as a way of dealing with the questions raised…

  17. Surveillance, insecticide resistance and control of an invasive Aedes aegypti (Diptera: Culicidae population in California [version 3; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Anthony J. Cornel

    2016-08-01

    Full Text Available The invasion and subsequent establishment in California of Aedes aegypti in 2013 has created new challenges for local mosquito abatement and vector control districts. Studies were undertaken to identify effective and economical strategies to monitor the abundance and spread of this mosquito species as well as for its control. Overall, BG Sentinel (BGS traps were found to be the most sensitive trap type to measure abundance and spread into new locations. Autocidal-Gravid-Ovitraps (AGO-B, when placed at a site for a week, performed equally to BGS in detecting the presence of female Ae. aegypti. Considering operational cost and our findings, we recommend use of BGS traps for surveillance in response to service requests especially in locations outside the known infestation area. We recommend AGO-Bs be placed at fixed sites, cleared and processed once a week to monitor mosquito abundance within a known infestation area. Long-term high density placements of AGO-Bs were found to show promise as an environmentally friendly trap-kill control strategy. California Ae. aegypti were found to be homozygous for the V1016I mutation in the voltage gated sodium channel gene, which is implicated to be involved in insecticide resistance. This strain originating from Clovis, California was resistant to some pyrethroids but not to deltamethrin in bottle bio-assays. Sentinel cage ultra-low-volume (ULV trials using a new formulation of deltamethrin (DeltaGard® demonstrated that it provided some control (average of 56% death in sentinel cages in a 91.4 m spray swath after a single truck mounted aerial ULV application in residential areas.

  18. Surveillance, insecticide resistance and control of an invasive Aedes aegypti (Diptera: Culicidae population in California [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Anthony J. Cornel

    2016-03-01

    Full Text Available The invasion and subsequent establishment in California of Aedes aegypti in 2013 has created new challenges for local mosquito abatement and vector control districts. Studies were undertaken to identify effective and economical strategies to monitor the abundance and spread of this mosquito species as well as for its control. Overall, BG Sentinel (BGS traps were found to be the most sensitive trap type to measure abundance and spread into new locations. Autocidal-Gravid-Ovitraps (AGO-B, when placed at a site for a week, performed equally to BGS in detecting the presence of female Ae. aegypti. Considering operational cost and our findings, we recommend use of BGS traps for surveillance in response to service requests especially in locations outside the known infestation area. We recommend AGO-Bs be placed at fixed sites, cleared and processed once a week to monitor mosquito abundance within a known infestation area. Long-term high density placements of AGO-Bs were found to show promise as an environmentally friendly trap-kill control strategy. California Ae. aegypti were found to be homozygous for the V1016I mutation in the voltage gated sodium channel gene, which is implicated to be involved in insecticide resistance. This strain originating from Clovis, California was resistant to some pyrethroids but not to deltamethrin in bottle bio-assays. Sentinel cage ultra-low-volume (ULV trials using a new formulation of deltamethrin (DeltaGard® demonstrated that it provided some control (average of 56% death in sentinel cages in a 91.4 m spray swath after a single truck mounted aerial ULV application in residential areas.

  19. California Bioregions

    Data.gov (United States)

    California Department of Resources — California regions developed by the Inter-agency Natural Areas Coordinating Committee (INACC) were digitized from a 1:1,200,000 California Department of Fish and...

  20. Arsenic poisoning in cattle

    Energy Technology Data Exchange (ETDEWEB)

    McLennan, M.W.; Dodson, M.E.

    1972-06-01

    A case of acute arsenic poisoning in cattle was reported. The losses occurred on a property in the south east of South Australia. The weather had been hot for two or three days before the death occurred. The tank supplying the water trough had almost run dry. The cattle then attempted to meet their water requirements by drinking from the sheep dipping vat. A sample of rumen contents and a sample of water from the dipping vat were checked for arsenic. The rumen sample contained 45 ppM As/sub 2/O/sub 3/ and the sample of dipping fluid contained 200 ppM As. The lesions observed were similar to earlier reported arsenic poisoning. 5 references.

  1. Arsenic poisoning in livestock.

    Science.gov (United States)

    el Bahri, L; Ben Romdane, S

    1991-06-01

    Arsenic is an important heavy metal intoxicant to livestock. Arsenical pesticides present significant hazards to animal health. The toxicity of arsenic varies with several factors--its chemical form, oxidation states, solubility. The phenylarsonic compounds are the least toxic and are used as feed additives in swine and poultry rations. However, roxarsone has a higher absolute toxicity than arsanilic acid. The mechanism of action is related to its reaction with sulfhydryl groups values to enzyme function and to its ability to uncouple oxydative phosphorylation. Most animals excrete arsenic quite readily. Toxicoses caused by inorganic and aliphatic organic arsenicals result in a different clinical syndrome than that from the phenylarsonic compounds. Arsenic poisoning may be confused with other types of intoxication. The specific antidote for inorganic arsenical poisoning is dimercaprol (BAL).

  2. Ciguatera poisoning in Vanuatu.

    Science.gov (United States)

    Goodman, Anna; Williams, Thomas N; Maitland, Kathryn

    2003-02-01

    Ciguatera poisoning is endemic in many tropical and subtropical countries. We conducted a retrospective study of admissions to two hospitals on the islands of Vanuatu in the southwestern Pacific region. We estimated the annual hospital admission rate for fish poisoning to be 65 (95% confidence interval [CI] = 55-75)/100,000 population on the island of Santo and 29 (95% CI = 19-43)/100,000 population on the island of Ambae. Hospital admission was more common in males 20-29 years old. Death was a rare complication. In the face of increases in both tourism and in the global trade in tropical and exotic fish, physicians in both endemic and non-endemic areas should be familiar with the epidemiology and clinical features of this important condition.

  3. [Control of toxicity of Sarcocystis fayeri in horsemeat by freezing treatment and prevention of food poisoning caused by raw consumption of horsemeat].

    Science.gov (United States)

    Harada, Seiya; Furukawa, Masato; Tokuoka, Eisuke; Matsumoto, Kazutoshi; Yahiro, Shunsuke; Miyasaka, Jiro; Saito, Morihiro; Kamata, Yoichi; Watanabe, Maiko; Irikura, Daisuke; Matsumoto, Hiroshi; Sugita-Konishi, Yoshiko

    2013-01-01

    More than 27 outbreaks per year of food poisoning caused by consuming horse meat were reported in Kumamoto Prefecture (including Kumamoto City) from January 2009 to September 2011. It was found that the causative agent of the outbreaks was a protein with a molecular weight of 15 kDa that had originated from bradyzoites of Sarcocystis fayeri parasitizing the horse meat. Rabit ileal loop tests showed that pepsin treatment of homogenates of frozen horse meat containing the cysts of S. fayeri induced loss of toxicity, presumably by digestion of the proteinous causative agent(s). Slices of horse meat containing the cysts were frozen at below -20°C for various periods. The cysts were collected after thawing the slices, then treated in an artificial stomach juice containing pepsin. The bradyzoites of the cysts kept at -20°C for 48 hr or more completely disappeared. Simultaneously, the 15 kDa protein also disappeared in the frozen cysts. After notifying the public and recommending freezing treatment of horse meat, no subsequent cases of food poisoning were reported. This indicates that freezing of horse meat is effective to prevent the occurrence of food poisoning caused by consuming raw horse meat containing S. fayeri.

  4. Lead Poison Detection

    Science.gov (United States)

    1976-01-01

    With NASA contracts, Whittaker Corporations Space Science division has developed an electro-optical instrument to mass screen for lead poisoning. Device is portable and detects protoporphyrin in whole blood. Free corpuscular porphyrins occur as an early effect of lead ingestion. Also detects lead in urine used to confirm blood tests. Test is inexpensive and can be applied by relatively unskilled personnel. Similar Whittaker fluorometry device called "drug screen" can measure morphine and quinine in urine much faster and cheaper than other methods.

  5. nsect poisons in museums

    Institute of Scientific and Technical Information of China (English)

    Eirik Granqvist

    2015-01-01

    Since natural history museums existed, there have been problems concerning how to protect the collections from damages caused by insects. In 1740s', French Chemist Becoeur started to use arsenic-soap to protect his taxidermy specimens against insects. But in the years of 1770s', it was discovered the terrible strong arsenic poison which was dangerous to human beings. Finally taxidermy specimens leave the use of ar- senic and borax to history and use Eulan in their place.

  6. Methaemoglobinemia in nitrobenzene poisoning.

    Directory of Open Access Journals (Sweden)

    Chongtham D

    1997-07-01

    Full Text Available A young girl with nitrobenzene induced methaemoglobinaemia was saved by the timely use of mechanical ventilator, administration of oral methylene blue and parenteral ascorbic acid. Though parenteral methylene blue is the antidote of choice, due to its non-availability, the laboratory preparation of methylene blue have been utilized orally. The rare occurrence of such cases, and the efficacy of oral methylene blue and other supportive measures in evading death due to Nitrobenzene poisoning have been highlighted.

  7. Homicidal arsenic poisoning.

    Science.gov (United States)

    Duncan, Andrew; Taylor, Andrew; Leese, Elizabeth; Allen, Sam; Morton, Jackie; McAdam, Julie

    2015-07-01

    The case of a 50-year-old man who died mysteriously after being admitted to hospital is reported. He had raised the possibility of being poisoned prior to his death. A Coroner's post-mortem did not reveal the cause of death but this was subsequently established by post-mortem trace element analysis of liver, urine, blood and hair all of which revealed very high arsenic concentrations.

  8. Alternativas de control en la pudrición radical de cebolla para el Valle de la Trinidad, Baja California Control Alternatives for Onion root rot in the Trinity Valley, Baja California

    Directory of Open Access Journals (Sweden)

    Armando Pulido-Herrera

    2012-02-01

    Full Text Available La pudrición radical en cebolla es la enfermedad más importante en el Valle de la Trinidad, Baja California, México. Con el propósito de evaluar estrategias de control para la enfermedad se realizaron tres experimentos durante 2007, 2008 y 2009. En el experimento I (2007 los tratamientos fueron: 1 Tiofanato metílico; 2 Smicobac (Trichoderma + Bacillus sp. + Azospirillum sp. + Pseudomonas sp.; 3 estiércol de bovino (EB; 4 residuos de cebolla (RC; 5 solarización plástico transparente (SPT, 6 solarización plástico negro (SPN; 7 SPT + EB; 8 SPT + RC; 9 SPN + EB; 10 SPN + RC; 11 Trichodef (Trichoderma harzianum;y 12testigo. En el experimento II (2008, los tratamientos fueron los mismos excepto el tratamiento 2, sustituido porprotector (extractos vegetales; y en el experimento III (2009 los tratamientos fueron: 1 SPT + estiércol de ovino (EO; 2 SPN + EO; 3 SPT; 4 SPN; 5 control biológico (Trichoderma spp.; y 6 control químico (2- (tiocianometiltio benzotiazol 30%. Los resultados indicaron que los tratamientos solarización plástico transparente con o sin enmiendas orgánicas, presentaron incrementos significativos (p≤ 0.05 de 22 a 34% en el rendimiento y diámetro del bulbo con respecto al control biológico y químico; sin embargo, en estos dos últimos tratamientos la incidencia y severidad se redujo significativamente (p≤ 0.05, por lo que la solarización con plástico transparente y el control biológico, son alternativas viables para el control de la pudrición radical en cultivos de cebolla en Baja California, México.Onion's root rot is the most important disease in the Trinidad Valle, Baja California, Mexico. In orderto evaluate strategies to control this disease, three experiments were conducted during 2007, 2008 and 2009. In experiment I (2007 the treatments were: 1 Thiophanate methyl; 2 Smicobac (Trichoderma+Bacillus sp. + Azospirillum sp. + Pseudomonas sp.; 3 cattle manure (EB; 4 waste of onion (RC; 5 clear plastic

  9. Fragmentation Considered Poisonous

    CERN Document Server

    Herzberg, Amir

    2012-01-01

    We present practical poisoning and name-server block- ing attacks on standard DNS resolvers, by off-path, spoofing adversaries. Our attacks exploit large DNS responses that cause IP fragmentation; such long re- sponses are increasingly common, mainly due to the use of DNSSEC. In common scenarios, where DNSSEC is partially or incorrectly deployed, our poisoning attacks allow 'com- plete' domain hijacking. When DNSSEC is fully de- ployed, attacker can force use of fake name server; we show exploits of this allowing off-path traffic analy- sis and covert channel. When using NSEC3 opt-out, attacker can also create fake subdomains, circumvent- ing same origin restrictions. Our attacks circumvent resolver-side defenses, e.g., port randomisation, IP ran- domisation and query randomisation. The (new) name server (NS) blocking attacks force re- solver to use specific name server. This attack allows Degradation of Service, traffic-analysis and covert chan- nel, and also facilitates DNS poisoning. We validated the attac...

  10. Organophosphate poisoning : A review

    Directory of Open Access Journals (Sweden)

    Parmod K. Sinha

    2003-06-01

    Full Text Available Organophosphate pesticides are used extensively worldwide, and poisoning by these agents, particularly in developing nations is a public health problem. Organophosphorous nerve agents are still considered as potential threat in both military or terrorism situations. The mechanism of toxicity is the inhibition of acetylcholinesterase, resulting in accumulation of the neurotransmitter acetylcholine and continued stimulation of acetylcholine receptors both in central and peripheral nervous systems. Beside acute cholinergic crisis, organophosphates are capable of producing several subacute or chronic neurological syndromes. The well described intermediate syndrome (IMS emerges 1-4 days after an apparently well treated cholinergic crisis. The standard treatment consists of reactivation of inhibited acetylcholinesterase with an oxime antidote (pralidoxime, obidoxime, HI-6 and Hlo7 and reversal of the biochemical effects of acetylcholine with atropine. The newer oximes HI-6 and Hlo& are much more suitable and efficacious acetylcholinesterase reactivator for severe acute nerve agent induced poisoning than currently used pralidoxime or obidoxime. Patients who receive treatment promptly usually recover from acute toxicity but may suffer from neurologic sequelae. (Med J Indones 2003; 12: 120-6 Keywords: poisoning, insecticide, organophosphate (OP, carbamates, acetylcholinesterase, oxime, pralidoxime, obidoxime, HI-6, HLo7

  11. Chronic arsenic poisoning.

    Science.gov (United States)

    Hall, Alan H

    2002-03-10

    Symptomatic arsenic poisoning is not often seen in occupational exposure settings. Attempted homicide and deliberate long-term poisoning have resulted in chronic toxicity. Skin pigmentation changes, palmar and plantar hyperkeratoses, gastrointestinal symptoms, anemia, and liver disease are common. Noncirrhotic portal hypertension with bleeding esophageal varices, splenomegaly, and hypersplenism may occur. A metallic taste, gastrointestinal disturbances, and Mee's lines may be seen. Bone marrow depression is common. 'Blackfoot disease' has been associated with arsenic-contaminated drinking water in Taiwan; Raynaud's phenomenon and acrocyanosis also may occur. Large numbers of persons in areas of India, Pakistan, and several other countries have been chronically poisoned from naturally occurring arsenic in ground water. Toxic delirium and encephalopathy can be present. CCA-treated wood (chromated copper arsenate) is not a health risk unless burned in fireplaces or woodstoves. Peripheral neuropathy may also occur. Workplace exposure or chronic ingestion of arsenic-contaminated water or arsenical medications is associated with development of skin, lung, and other cancers. Treatment may incklude the use of chelating agents such as dimercaprol (BAL), dimercaptosuccinic acid (DMSA), and dimercaptopanesulfonic acid (DMPS).

  12. Study on 6 011 cases of acute poisoning in Guangxi from 2005 to 2009:case analysis and prevention-control scheme%2005~2009年广西急性中毒6011例分析及防控宣教对策探讨

    Institute of Scientific and Technical Information of China (English)

    蒋东方; 张振明; 陈雪冬; 龙永美; 何德智

    2015-01-01

    Objective To investigate the characteristics and prevention-control scheme of acute-poisoning in Guangxi.Methods The retrospective analysis on the data of 6 011 patients with acute poisoning from the hospitals of 11 cities in Guangxi from 2005 to 2009was conducted.Results The people with employment(68.84%) and secondary school education or above(53.42%) were the mainpopulation of acute poisoning.The onset of acute poisoning mainly occurred at home(79.53%),and peroral poisoning was most common(69.45%).The proportion of poisoning without consciousness(61.59%) was significantly higher than that of poisoning with consciousness(37.31%).The main toxicants included pesticides,chemical and medicine toxicants,which accounted for 75.00%.Conclusion Forimproving self-protective consciousness and skills of people from different places,the specific measures of acute-poisoning education shouldbe formulated according to the characteristics of poisoning population,poisoning process,poisoning causes and toxicants,and differencesbetween cities and countries.%目的 探讨广西急性中毒的特点及防控对策. 方法 回顾性分析2005 ~2009 年广西11 个市及其县级医院、乡镇卫生院6 011例急性中毒患者的病历资料. 结果 中毒人群以就业人群(68.84%)与中学及以上学历者(53.42%)为主. 中毒过程以发生在家中(占79.53%)与经口中毒(占69.45%)最常见;无意识性中毒者比例(占61.59%)明显高于有意识性中毒(占37.31%). 中毒毒物主要为农药、化学、医药3 类,占75.00%. 结论 应根据中毒人群、中毒过程及原因、毒物特点及城乡差别,制订针对性的宣教措施,以提高各地人群的自我防毒意识与技能.

  13. Parathion poisoning of Mississippi kites in Oklahoma

    Science.gov (United States)

    Franson, J. Christian

    1994-01-01

    Parathion(phosphorothioic acid O, O-diethyl O-[4-nitrophenyl] ester) is a broad spectrum organophosphorus insecticide, used on a variety of crops and occasionally for mosquito control, and is highly toxic to birds (Smith 1987). Intentional poisoning with parathion is reported to have killed more than 8000 red-winged blackbirds (Agelaius phoeniceus), common grackles (Quiscalus quiscula), brown-headed cowbirds (Molothrus ater) and European starlings (Sturnus vulgaris) in two separate instances (Stone et al. 1984). Use of parathion on wheat fields has resulted in the mortality of about 1600 Canada geese (Branta canadensis) and other waterfowl in one instance (White et al. 1982) and about 200 Canada geese in another (Flickinger et al. 1991). More than 200 laughing gulls (Larus atricilla) died near cotton fields treated with parathion (White et al. 1979). Secondary poisoning of raptors resulting from the consumption of prey exposed to parathion, has been reported experimentally and in the field. Stone et al. (1984) found two dead red-tailed hawks (Buteo jamaicensis), a Cooper's hawk (Accipiter cooperii) and an American kestrel (Falco sparverius) that had fed on blackbirds killed by parathion. One of four American kestrels died after being fed cricket frogs (Acris crepitans) that had been exposed to 10ppm parathion for 96 hr (Fleming et al. 1982). The Mississippi kite (Ictinia mississippensis) is highly insectivorous (Brown and Amadon 1968) and is thus subject to secondary poisoning resulting from consumption of insects exposed to pesticides. I report here an instance of secondary parathion poisoning in wild Mississippi kites.

  14. Chelation Therapy for Mercury Poisoning

    OpenAIRE

    Rong Guan; Han Dai

    2009-01-01

    Chelation therapy has been the major treatment for heavy metal poisoning. Various chelating agents have been developed and tested for treatment of heavy metal intoxications, including mercury poisoning. It has been clearly shown that chelating agents could rescue the toxicity caused by heavy metal intoxication, but the potential preventive role of chelating agents against heavy metal poisoning has not been explored much. Recent paper by Siddiqi and colleagues has suggested a protective role o...

  15. Emergency care outcomes of acute chemical poisoning cases in Rawalpindi

    Institute of Scientific and Technical Information of China (English)

    Ibrar Rafique; Umbreen Akhtar; Umar Farooq; Mussadiq Khan; Junaid Ahmad Bhatti

    2016-01-01

    Objective: To assess the emergency care outcomes of acute chemical poisoning cases in tertiary care settings in Rawalpindi, Pakistan. Methods: The data were extracted from an injury surveillance study conducted in the emergency departments (ED) of three tertiary care hospitals of Rawalpindi city from July 2007 to June 2008. The World Health Organization standard reporting questionnaire (one page) was used for recording information. Associations of patients' characteristics with ED care outcomes, i.e., admitted vs. discharged were assessed using logistic regression models. Results: Of 62 530 injury cases reported, chemical poisoning was identified in 434 (0.7%) cases. The most frequent patient characteristics were poisoning at home (61.9%), male gender (58.6%), involving self-harm (46.0%), and youth aged 20–29 years (43.3%). Over two-thirds of acute poisoning cases (69.0%) were admitted. Acute poisoning cases were more likely to be admitted if they were youth aged 10–19 years [odds ratio (OR)=4.41], when the poisoning occurred at home (OR=21.84), and was related to self-harm (OR=18.73) or assault (OR=7.56). Conclusions: Findings suggest that controlling access of poisonous substances in youth and at homes might reduce related ED care burden. Safety promotion agencies and emergency physicians can use these findings to develop safety messages.

  16. Processes controlling water and hydrocarbon composition in seeps from the Salton Sea geothermal system, California, USA

    Science.gov (United States)

    Svensen, Henrik; Karlsen, Dag A.; Sturz, Anne; Backer-Owe, Kristian; Banks, David A.; Planke, Sverre

    2007-01-01

    Water-, mud-, gas-, and petroleum-bearing seeps are part of the Salton Sea geothermal system (SSGS) in Southern California. Seeps in the Davis-Schrimpf seep field (˜14,000 m2) show considerable variations in water temperature, pH, density, and solute content. Water-rich springs have low densities (98 vol%). Halogen geochemistry of the waters indicates that mixing of deep and shallow waters occurs and that near-surface dissolution of halite may overprint the original fluid compositions. Carbon isotopic analyses suggest that hydrocarbon seep gases have a thermogenic origin. This hypothesis is supported by the presence of petroleum in a water-dominated spring, composed of 53% saturated compounds, 35% aromatics, and 12% polar compounds. The abundance of polyaromatic hydrocarbons and immature biomarkers suggests a hydrothermal formation of the petroleum, making the SSGS a relevant analogue to less accessible hydrothermal seep systems, e.g., the Guaymas Basin in the Gulf of California.

  17. Occupant comfort, control, and satisfaction in three California mixed-mode office buildings

    OpenAIRE

    Ring, Erik W; Brager, Gail S.

    2000-01-01

    This report outlines the results from an occupant survey of satisfaction with thermal comfort and air quality in three California mixed-mode office buildings. Mixed-mode refers to the relatively new design strategy of explicitly integrating natural ventilation with mechanical cooling and ventilation services. Each of the research sites includes operable windows along with a complete HVAC system. Survey results indicate that access to operable windows has a significant positive impact on repor...

  18. Pesticide poisoning: a major health problem in Sri Lanka

    DEFF Research Database (Denmark)

    Hoek, Wim van der; Konradsen, F; Athukorala, K;

    1998-01-01

    pesticides is the most important reason for this high number of poisoning cases. The frequent application of highly hazardous pesticides in high concentrations was often irrational and posed serious health and financial risks to the farmers. Sales promotion activities and credit facilities promoted...... in an immediate health benefit. Improved agricultural extension services to promote alternative non-chemical methods of pest control is the most important strategy, in the long term, to prevent acute pesticide poisoning....

  19. Treatment of toxicodendron dermatitis (poison ivy and poison oak).

    Science.gov (United States)

    Guin, J D

    2001-04-01

    Toxicodendron dermatitis results from a reaction to an oil soluble oleoresin that is present in many parts of the poison ivy and poison oak plants. Prophylactic measures include avoidance, protective clothing, barrier creams and hyposensitization. Treatments include washing the area immediately with a solvent suitable for lipids and the use of anti-inflammatory agents, especially corticosteroids.

  20. Recommended Changes to Specifications for Demand Controlled Ventilation in California's Title 24 Building Energy Efficiency Standards

    Energy Technology Data Exchange (ETDEWEB)

    Fisk, William J.; Sullivan, Douglas P.; Faulkner, David

    2010-04-08

    In demand-controlled ventilation (DCV), rates of outdoor air ventilation are automatically modulated as occupant density varies. The objective is to keep ventilation rates at or above design specifications and code requirements and also to save energy by avoiding excessive ventilation rates. DCV is most often used in spaces with highly variable and sometime dense occupancy. In almost all cases, carbon dioxide (CO{sub 2}) sensors installed in buildings provide the signal to the ventilation rate control system. People produce and exhale CO{sub 2} as a consequence of their normal metabolic processes; thus, the concentrations of CO{sub 2} inside occupied buildings are higher than the concentrations of CO{sub 2} in the outdoor air. The magnitude of the indoor-outdoor CO{sub 2} concentration difference decreases as the building's ventilation rate per person increases. The difference between the indoor and outdoor CO{sub 2} concentration is also a proxy for the indoor concentrations of other occupant-generated bioeffluents, such as body odors. Reviews of the research literature on DCV indicate a significant potential for energy savings, particularly in buildings or spaces with a high and variable occupancy. Based on modeling, cooling energy savings from applications of DCV are as high as 20%. With support from the California Energy Commission and the U.S. Department of Energy, the Lawrence Berkeley National Laboratory has performed research on the performance of CO{sub 2} sensing technologies and optical people counters for DCV. In addition, modeling was performed to evaluate the potential energy savings and cost effectiveness of using DCV in general office spaces within the range of California climates. The above-described research has implications for the specifications pertaining to DCV in section 121 of the California Title 24 Standard. Consequently, this document suggests possible changes in these specifications based on the research findings. The suggested

  1. Ciguatera fish poisoning: treatment, prevention and management.

    Science.gov (United States)

    Friedman, Melissa A; Fleming, Lora E; Fernandez, Mercedes; Bienfang, Paul; Schrank, Kathleen; Dickey, Robert; Bottein, Marie-Yasmine; Backer, Lorraine; Ayyar, Ram; Weisman, Richard; Watkins, Sharon; Granade, Ray; Reich, Andrew

    2008-01-01

    Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world, and it causes substantial physical and functional impact. It produces a myriad of gastrointestinal, neurologic and/or cardiovascular symptoms which last days to weeks, or even months. Although there are reports of symptom amelioration with some interventions (e.g. IV mannitol), the appropriate treatment for CFP remains unclear to many physicians. We review the literature on the treatments for CFP, including randomized controlled studies and anecdotal reports. The article is intended to clarify treatment options, and provide information about management and prevention of CFP, for emergency room physicians, poison control information providers, other health care providers, and patients.

  2. Ciguatera Fish Poisoning: Treatment, Prevention and Management

    Directory of Open Access Journals (Sweden)

    Andrew Reich

    2008-08-01

    Full Text Available Ciguatera Fish Poisoning (CFP is the most frequently reported seafood-toxin illness in the world, and it causes substantial physical and functional impact. It produces a myriad of gastrointestinal, neurologic and/or cardiovascular symptoms which last days to weeks, or even months. Although there are reports of symptom amelioration with some interventions (e.g. IV mannitol, the appropriate treatment for CFP remains unclear to many physicians. We review the literature on the treatments for CFP, including randomized controlled studies and anecdotal reports. The article is intended to clarify treatment options, and provide information about management and prevention of CFP, for emergency room physicians, poison control information providers, other health care providers, and patients.

  3. Amnesic shellfish poisoning: A review

    NARCIS (Netherlands)

    Apeldoorn ME van; Egmond HP van; Speijers GJA; CSR; ARO; CSR

    1999-01-01

    This review reports information on the amnesic shellfish poisoning (ASP) syndrome and the ASP toxins causing this poisoning, of which domoic acid is the major component. Data includes chemical structures and detection methods of ASP toxins, sources of ASP toxins, marine organisms associated with ASP

  4. Neurology of acute organophosphate poisoning

    Directory of Open Access Journals (Sweden)

    Singh Gagandeep

    2009-01-01

    Full Text Available Acute organophosphate (OP poisoning is one of the most common poisonings in emergency medicine and toxicological practice in some of the less-developed nations in South Asia. Traditionally, OP poisoning comes under the domain of emergency physicians, internists, intensivists, and toxicologists. However, some of the complications following OP poisoning are neurological and involve neurologists. The pathophysiological basis for the clinical manifestations of OP poisoning is inactivation of the enzyme, acetylcholinesterase at the peripheral nicotinic and muscarinic and central nervous system (CNS nerve terminals and junctions. Nicotinic manifestations occur in severe cases and late in the course; these comprise of fasciculations and neuromuscular paralysis. There is a good correlation between the electrophysiological abnormalities and the severity of the clinical manifestations. Neurophysiological abnormalities characteristic of nicotinic junctions (mainly neuromuscular junction dysfunction include: (1 single, supramaximal electrical-stimulus-induced repetitive response/s, (2 decrement-increment response to high frequency (30 Hz repetitive nerve stimulation (RNS, and (3 decremental response to high frequency (30 Hz RNS. Atropine ameliorates muscarinic manifestations. Therapeutic agents that can ameliorate nicotinic manifestations, mainly neuromuscular, are oximes. However, the evidence for this effect is inconclusive. This may be due to the fact that there are several factors that determine the therapeutic effect of oximes. These factors include: The OP compound responsible for poisoning, duration of poisoning, severity of poisoning, and route of exposure. There is also a need to study the effect of oximes on the neurophysiological abnormalities.

  5. Extracorporeal Treatment for Lithium Poisoning

    DEFF Research Database (Denmark)

    Decker, Brian S; Goldfarb, David S; Dargan, Paul I

    2015-01-01

    The Extracorporeal Treatments in Poisoning Workgroup was created to provide evidence-based recommendations on the use of extracorporeal treatments in poisoning. Here, the EXTRIP workgroup presents its recommendations for lithium poisoning. After a systematic literature search, clinical and toxico......The Extracorporeal Treatments in Poisoning Workgroup was created to provide evidence-based recommendations on the use of extracorporeal treatments in poisoning. Here, the EXTRIP workgroup presents its recommendations for lithium poisoning. After a systematic literature search, clinical...... extraction of patient-level data. The workgroup concluded that lithium is dialyzable (Level of evidence=A) and made the following recommendations: Extracorporeal treatment is recommended in severe lithium poisoning (1D). Extracorporeal treatment is recommended if kidney function is impaired and the [Li...... treatment (1D), but continuous RRT is an acceptable alternative (1D). The workgroup supported the use of extracorporeal treatment in severe lithium poisoning. Clinical decisions on when to use extracorporeal treatment should take into account the [Li(+)], kidney function, pattern of lithium toxicity...

  6. [Accidental oral mercurochrome poisoning].

    Science.gov (United States)

    Ayala Curiel J; Nieto Conde C; Santana Rodríguez C; Urbón Artero A; Gracia Remiro R

    2000-11-01

    Neonatal mercury poisoning, especially that due to merbromin ingestion, is uncommon. We describe the case of a 10 day old newborn infant who was given mercurochrome orally for 7 days due to misunderstanding of medical instructions. Initial symptoms included loss of appetite and low weight increase. Elevated blood mercury concentrations were found. Chelating therapy with dimercaprol was initiated and the patient's evolution was good. We discuss the potential toxicity of mercury and emphasise the importance of the transmission of information by physicians, especially to the immigrant population.

  7. Juniper tar poisoning.

    Science.gov (United States)

    Koruk, Suda Tekin; Ozyilkan, Esin; Kaya, Pinar; Colak, Dilsen; Donderici, Omer; Cesaretli, Yildirim

    2005-01-01

    Juniper tar (cade oil) is distilled from the branches and wood of Juniperus oxycedrus. It contains etheric oils, triterpene and phenols, and is used for many purposes in folk medicine. A case is reported of a previously healthy man who ingested a spoonful of home-made extract of Juniperus oxycedrus. The poisoning caused fever, severe hypotension, renal failure, hepatotoxicity, and severe cutaneous burns on the face. After supportive and symptomatic treatment, the patient improved and was discharged in a good condition on the eleventh day.

  8. Cow dung powder poisoning

    OpenAIRE

    Khaja Mohideen Sherfudeen; Senthil Kumar Kaliannan; Pavan Kumar Dammalapati

    2015-01-01

    Cow dung, which has germicidal property, was used in ancient days to clean living premises in South India. Nowadays, people are using commercially available synthetic cow dung powder. It is locally known as “saani powder” in Tamil Nadu. It is freely available in homes and is sometimes accidentally consumed by children. It is available in two colors - yellow and green. Cow dung powder poisoning is common in districts of Tamil Nadu such as Coimbatore, Tirupur, and Erode. We report two cases of ...

  9. Suicide through doxylamine poisoning.

    Science.gov (United States)

    Bockholdt, B; Klug, E; Schneider, V

    2001-06-01

    Doxylamine is an antihistamine of the ethanolamine class. It is used primarily as a sleep-inducing agent. Only a few reports can be found in the literature about lethal intoxications with doxylamine, but many with combined intoxications. Doxylamine is, aside from diphenhydramine, the only chemically defined active ingredient in some sleeping medications which is available without a prescription in the Federal Republic of Germany. Two cases of doxylamine poisoning are presented, in which high doxylamine concentrations were found in the blood and organs.

  10. Cartap hydrochloride poisoning: a case report

    OpenAIRE

    Sumesh Raj; Sheetal S.

    2014-01-01

    Cartap hydrochloride is a thiocarbamate insecticide used for control of chewing and sucking insects of all stages of development, on many crops. It is an analogue of nereistoxin. Poisoning with cartap is very rarely reported from India. We report a 46 year old man who consumed cartap with alcohol, presented with nausea & vomiting and improved with supportive measures. [Int J Res Med Sci 2014; 2(1.000): 360-361

  11. Staphylococcal food poisoning on a cruise ship.

    OpenAIRE

    Waterman, S H; Demarcus, T. A.; Wells, J G; Blake, P A

    1987-01-01

    Two waves of vomiting and/or diarrhoea affected approximately 215 of the 715 passengers on a Caribbean cruise ship. The outbreak was independently associated with eating cream-filled pastries at two separate meals. Staphylococcus aureus phage type 85/+ was isolated from cases and pastry cooks, but not from controls. This is the first well-documented outbreak of staphylococcal food poisoning on a cruise ship.

  12. Toxic Bradycardias in the Critically Ill Poisoned Patient

    Directory of Open Access Journals (Sweden)

    Melissa L. Givens

    2012-01-01

    Full Text Available Cardiovascular drugs are a common cause of poisoning, and toxic bradycardias can be refractory to standard ACLS protocols. It is important to consider appropriate antidotes and adjunctive therapies in the care of the poisoned patient in order to maximize outcomes. While rigorous studies are lacking in regards to treatment of toxic bradycardias, there are small studies and case reports to help guide clinicians’ choices in caring for the poisoned patient. Antidotes, pressor support, and extracorporeal therapy are some of the treatment options for the care of these patients. It is important to make informed therapeutic decisions with an understanding of the available evidence, and consultation with a toxicologist and/or regional Poison Control Center should be considered early in the course of treatment.

  13. Serum Metabolomics in Rats after Acute Paraquat Poisoning.

    Science.gov (United States)

    Wang, Zhiyi; Ma, Jianshe; Zhang, Meiling; Wen, Congcong; Huang, Xueli; Sun, Fa; Wang, Shuanghu; Hu, Lufeng; Lin, Guanyang; Wang, Xianqin

    2015-01-01

    Paraquat is one of the most widely used herbicides in the world and is highly toxic to humans and animals. In this study, we developed a serum metabolomic method based on GC/MS to evaluate the effects of acute paraquat poisoning on rats. Pattern recognition analysis, including both principal component analysis and partial least squares-discriminate analysis revealed that acute paraquat poisoning induced metabolic perturbations. Compared with the control group, the level of octadecanoic acid, L-serine, L-threonine, L-valine, and glycerol in the acute paraquat poisoning group (36 mg/kg) increased, while the levels of hexadecanoic acid, D-galactose, and decanoic acid decreased. These findings provide an overview of systematic responses to paraquat exposure and metabolomic insight into the toxicological mechanism of paraquat. Our results indicate that metabolomic methods based on GC/MS may be useful to elucidate the mechanism of acute paraquat poisoning through the exploration of biomarkers.

  14. 76 FR 5319 - Revisions to the California State Implementation Plan, Santa Barbara Air Pollution Control...

    Science.gov (United States)

    2011-01-31

    ... Control District, Placer County Air Pollution Control District, Antelope Valley Air Quality Management District, and Ventura County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA... Control District (SBAPCD), Placer County Air Pollution Control District (PCAPCD), Antelope Valley...

  15. CLINICAL STUDY OF ACUTE POISONING

    Directory of Open Access Journals (Sweden)

    Panduranga

    2014-09-01

    Full Text Available BACKGROUND AND OBJECTIVE: Acute poisoning is an important medical emergency. Studies of this nature will be useful tool in planning, early diagnosis and management of acute poisoning cases. The objective of the study are to study the clinical features, diagnosis and management, morbidity and mortality of various acute poisoning. METHODOLOGY: This study comprises of 350 patients of acute poisoning admitted to Chigateri General Hospital and Bapuji Hospital attached to J. J. M. Medical College, Davangere, between 1st March 2011 to 31st October 2011. REUSLTS: Out of 350 cases of acute poisoning studied, there were 268 males and 82 females. Males comprised 76.57%and females 23.42% of the total, in this series, Organophosphorous compounds were the commonest (30%, majority of the patients hailed from rural area 70%. Mortality is 10.57%.

  16. Analysis of current situation of poisoning caused by poisonous animals, poisinous plants, and poisonous mushrooms in China%我国有毒动物、有毒植物、毒蕈中毒现况分析

    Institute of Scientific and Technical Information of China (English)

    何仟; 谢立璟; 马沛滨; 孙承业

    2013-01-01

    Objective To understand the current situation of poisoning caused by poisonous animals,poisonous plants,and poisonous mushrooms in our country in order to understand the direction of work for controlling poisoning caused by poisonous organisms and to provide scientific basis for the research on key technique for controlling poisoning.Methods China Hospital Knowledge Database and Wanfang Database were searched,and published literature regarding poisoning cases or events caused by poisonous animals,poisonous plants,and poisonous mushrooms in 1994-2011 was collected.The data was analyzed using retrospective descriptive epidemiological methods.Results Three thousand four hundred and sixtythree articles consistent with the criteria were collected and a total of 94 700 poisonous patients were reported,of which 46 110 were produced by poisonous animals,37 172 produced by poisonous plants,and 11 418 produced by poisonous mushrooms.Poisoning mainly occurred in the south area which was abundant in various species and the case distribution was nearly consistent with that of the species.The spectrum of poison were relatively concentrated in several families,and in the number of poisoning cases caused by the top 5 poison categories,poisonous animals and poisonous plants accounted for 78.77% (36 321/46 110)and 84.03% (31 234/37 172) of total number of poisoning cases caused by the 2 kinds of poisonous organisms,respectively.The main categories of poisonous animals causing poisoning were toxic snakes,fish gall bladder,and puffer fish and main plants; the main categories of poisonous plants causing poisoning were Leguminosae and Ranunculaceae.Most poisonous mushrooms poisoning was due to unknown species which accounted for 77.09% (8802/11 418),and Amanitaceae and Boletaceae were the most common mushrooms in known poisonous mushroom poisoning.The main causes of poisoning were accidents (50.24%,41 291/82 185) and mistaken ingestion (42.19%,34 670/82 185) and the main route

  17. [Arsenic - Poison or medicine?].

    Science.gov (United States)

    Kulik-Kupka, Karolina; Koszowska, Aneta; Brończyk-Puzoń, Anna; Nowak, Justyna; Gwizdek, Katarzyna; Zubelewicz-Szkodzińska, Barbara

    2016-01-01

    Arsenic (As) is commonly known as a poison. Only a few people know that As has also been widely used in medicine. In the past years As and its compounds were used as a medicine for the treatment of such diseases as diabetes, psoriasis, syphilis, skin ulcers and joint diseases. Nowadays As is also used especially in the treatment of patients with acute promyelocytic leukemia. The International Agency for Research on Cancer (IARC) has recognized arsenic as an element with carcinogenic effect evidenced by epidemiological studies, but as previously mentioned it is also used in the treatment of neoplastic diseases. This underlines the specificity of the arsenic effects. Arsenic occurs widely in the natural environment, for example, it is present in soil and water, which contributes to its migration to food products. Long exposure to this element may lead to liver damages and also to changes in myocardium. Bearing in mind that such serious health problems can occur, monitoring of the As presence in the environmental media plays a very important role. In addition, the occupational risk of As exposure in the workplace should be identified and checked. Also the standards for As presence in food should be established. This paper presents a review of the 2015 publications based on the Medical database like PubMed and Polish Medical Bibliography. It includes the most important information about arsenic in both forms, poison and medicine.

  18. Cleistanthus collinus poisoning

    Directory of Open Access Journals (Sweden)

    Anugrah Chrispal

    2012-01-01

    Full Text Available Cleistanthus collinus, a toxic shrub, is used for deliberate self-harm in rural South India. MEDLINE (PUBMED and Google were searched for published papers using the search/ MeSH terms "Cleistanthus collinus," "Euphorbiaceae," "Diphyllin," "Cleistanthin A," Cleistanthin B" and "Oduvanthalai." Non-indexed journals and abstracts were searched by tracing citations in published papers. The toxic principles in the leaf include arylnaphthalene lignan lactones - Diphyllin and its glycoside derivatives Cleistanthin A and B. Toxin effect in animal models demonstrate neuromuscular blockade with muscle weakness, distal renal tubular acidosis (dRTA and type 2 respiratory failure with conflicting evidence of cardiac involvement. Studies suggest a likely inhibition of thiol/thiol enzymes by the lignan-lactones, depletion of glutathione and ATPases in tissues. V-type H+ ATPase inhibition in the renal tubule has been demonstrated. Mortality occurs in up to 40% of C. collinus poisonings. Human toxicity results in renal tubular dysfunction, commonly dRTA, with resultant hypokalemia and normal anion gap metabolic acidosis. Aggressive management of these metabolic derangements is crucial. Acute respiratory distress syndrome (ARDS is seen in severe cases. Cardiac rhythm abnormalities have been demonstrated in a number of clinical studies, though the role of temporary cardiac pacemakers in reducing mortality is uncertain. Consumption of decoctions of C. collinus leaves, hypokalemia, renal failure, severe metabolic acidosis, ARDS and cardiac arrhythmias occur in severe poisonings and predict mortality. Further study is essential to delineate mechanisms of organ injury and interventions, including antidotes, which will reduce mortality.

  19. Organochlorine poisoning of herons

    Science.gov (United States)

    Ohlendorf, H.M.; Swineford, D.M.; Locke, L.N.

    1979-01-01

    Over a period of years interested individuals have submitted many dead or moribund herons of various species to our laboratory to learn whether the birds had been affected by diseases or organochlorine poisoning. Residue concentrations in carcasses of birds and mammals are considered the best measure of sublethal exposure, whereas residues in brains are best to use for diagnosing death by most organochlorine chemicals.... The purpose of the present paper is to document the occurrence and concentration of organochlorine residues in the brains of herons from various areas in the United States. By comparing these residue concentrations with laboratory-determined diagnostic lethal levels, we conclude that some herons were killed by organochlorine poisoning; others were at least seriously endangered by the residues they carried. Complete results of carcass analyses for these and other herons, as well as further details? on residues in brains, will be reported elsewhere. Overall, we analyzed carcasses or brains of more than 70 herons found dead or moribund and 36 others taken in planned collections. Residue levels in carcasses of many herons were not high enough to warrant analysis of brains. In the present paper we compare carcass and brain residues of dieldrin in 23 herons of which both carcass and brain were analyzed.

  20. California Conference on High Blood Pressure Control in the Spanish-Speaking Community (Los Angeles, California, April 1-2, 1978). Summary Report.

    Science.gov (United States)

    National Institutes of Health (DHEW), Bethesda, MD. High Blood Pressure Information Center.

    As part of the National High Blood Pressure Education Program effort, the conference explored the implications and impact of the prevalence of hypertension in Spanish-speaking populations in California. Approximately 150 experts in health fields, representing all levels of government, public and private health care providers, consumers, and health…

  1. Allium species poisoning in dogs and cats

    Directory of Open Access Journals (Sweden)

    BS Salgado

    2011-01-01

    Full Text Available Dogs and cats are the animals that owners most frequently seek assistance for potential poisonings, and these species are frequently involved with toxicoses due to ingestion of poisonous food. Feeding human foodstuff to pets may prove itself dangerous for their health, similarly to what is observed in Allium species toxicosis. Allium species toxicosis is reported worldwide in several animal species, and the toxic principles present in them causes the transformation of hemoglobin into methemoglobin, consequently resulting in hemolytic anemia with Heinz body formation. The aim of this review is to analyze the clinicopathologic aspects and therapeutic approach of this serious toxicosis of dogs and cats in order to give knowledge to veterinarians about Allium species toxicosis, and subsequently allow them to correctly diagnose this disease when facing it; and to educate pet owners to not feed their animals with Allium-containg food in order to better control this particular life-threatening toxicosis.

  2. Occupational poison ivy and oak dermatitis.

    Science.gov (United States)

    Epstein, W L

    1994-07-01

    Among the growing and diverse groups of outdoor and environmental workers, poison ivy and poison oak continue to be the major cause of occupational contact dermatitis. This article reviews the practical and theoretic means to prevent poison ivy and poison oak dermatitis in workers occupationally exposed to these weeds.

  3. Paleoceanographic and tectonic controls on deposition of the Monterey formation and related siliceous rocks in California

    Science.gov (United States)

    Barron, J.A.

    1986-01-01

    The timing of paleoceanographic and tectonic events that shaped the deposition of the Monterey Formation of California and related siliceous rocks has been determined by application of a refined biochronology. The base of the Monterey at 17.5 Ma coincides with rising global sea level and a switch in biogenous silica deposition from the Caribbean and low-latitude North Atlantic to the North Pacific. Major polar cooling, which began at 15 Ma, postdates the base of the Monterey by more than 2 Ma and cannot be invoked to cause the deposition of diatomaceous sediments occurring in the lowermost Monterey. Later polar cooling in the early late Miocene, however, apparently caused increased upwelling and deposition of purer diatomites in the upper Monterey. The top of the Monterey at about 6 Ma coincides with a major sea level drop and is commonly marked by an unconformity. Equivalent unconformities are widespread around the rim of the North Pacific and typically separate more pelagic sediments from overlying sediments with a greater terrigenous component. Above the Monterey, diatoms persist in California sediments to 4.5-4.0 m.y., where their decline coincides with increased deposition of diatoms in the Antarctic. Carbon isotope records in the Pacific and Indian Oceans record storage of 12C in the Monterey Formation and equivalent organic-rich sediments around the rim of the North Pacific. A +1.0??? excursion in ?? 13C beginning at 17.5 Ma coincides with rising sea level and probably reflects storage of organic material in Monterey-like marginal reservoirs. A reverse -1.0??? shift at 6.2 Ma closely approximates the top of the Monterey and may represent erosion of these marginal reservoirs and reintroduction of stored organic carbon into the ocean-atmosphere system. Initiation of transform faulting and extension in the California margin in the latest Oligocene and early Miocene caused the subsidence of basins which later received Monterey sediments. A major tectonic event

  4. Trends in Suicide by Poisoning in China 2000-2006: Age, Gender,Method, and Geography

    Institute of Scientific and Technical Information of China (English)

    XING ZHANG; HAI-SHAN LI; QIU-HONG ZHU; JING ZHOU; SHUANG ZHAN; LIN ZHANG; CHENG-YE SUN

    2008-01-01

    Objective This study analyzed patterns of suicide and suicide attempts by poisoning as reported through a national poison control system for the purpose of improving intervention and prevention. Methods During the period of 2000 to 2006, 6440 cases of poisoning suicide were reported to the telephone consultation service system of The National Center for Poisoning Control (Chinese Center for Disease Control and Prevention). Among these records, 4728 cases had completed data for this analysis in terms of age, sex, trend of time and location, and type of poisons. Results There were 60.6% female cases with the age from 10 to 90 years old. The age of cases from 20 to 39 years accounted for 54.5% of all age groups. Both the numbers and percentage in record related to poisoning consultation of oral poisoning suicide showed an increasing tendency during the 7 years. In particular, there was a drastic increase from 2004 to 2006. In addition, the high frequency of cases occurred from May to October. Hebei, Shandong, Henan, and Anhui Provinces had the highest number of cases. Pesticide poisonings were the most cormmon method in these cases of consultation for suicide and suicide attempts. Conclusion This study describes epidemiological characteristics in the oral poisoning suicide cases and provides scientific basis for suicide prevention interventions.

  5. Birth control pills overdose

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/002599.htm Birth control pill overdose To use the sharing features on ... the medicine was prescribed for the person Poison Control Your local poison center can be reached directly ...

  6. [Cases of poisoning in Germany. Disease entity, documentation, and aspects of the event].

    Science.gov (United States)

    Hahn, A; Begemann, K; Stürer, A

    2014-06-01

    , followed by suicidal action (20 %), with abuse and industrial poisoning (4 %) in third position; 1 % of the cases of poisoning were attributed to adverse drug reactions (ADR) and mistaking a medicinal product for another one. Infants aged 1-2 years have the highest risk of poisoning. A panel of the BfR Committee for the Assessment of Poisonings has already developed proposals for a national monitoring scheme of poisoning incidents. The aim is to prepare annual reports similar to the report of the National Poison Data System (NPDS) maintained by the American Association of Poison Control Centers (AAPCC) in the USA.

  7. Dominant Factors Controlling the Hydrometeorology of Northern California: Landfalling Atmospheric Rivers and Sierra Barrier Jets

    Science.gov (United States)

    Neiman, P. J.; Ralph, F. M.; Hughes, M.; Sukovich, E.; Kingsmill, D. E.; Zamora, R. J.; Moore, B. J.

    2014-12-01

    Northern California's Sierra Nevada and Shasta-Trinity mountains are key to the state's water supply and can contribute to major floods in the Central Valley (CV). NOAA's Hydrometeorology Testbed (HMT) program and the CalWater experiment have discovered much about how landfalling atmospheric rivers (AR) and Sierra Barrier Jets (SBJ) modulate orographic precipitation in that region. This presentation provides a review of recent findings, both from case-study and compositing perspectives. Wind-profiler and global-positioning-system (GPS) observations are used with soil moisture probes, stream gauges, and a regional reanalysis dataset. Key results include: Inland-directed ARs override a ~1-km-deep, Sierra-parallel SBJ located above the CV and the western slope of the Sierra. Above the developing SBJ, strengthening southwesterly flow marks the AR. The moistening SBJ reaches maximum intensity during the strongest AR flow aloft, at which time the core of the AR-parallel vapor transport slopes over the SBJ and intersects the Sierra. The SBJ then weakens with the initial cold-frontal passage aloft. A statistical analysis of orographic forcing reveals that both the AR and SBJ are crucial in determining the distribution of precipitation in the northern Sierra and Shasta-Trinity regions due to orographic precipitation enhancement. An open question remains regarding the transport of water vapor near the northern end of the CV. Namely, a portion of the AR-modulated SBJ flow may be transported through a prominent gap in the terrain between Mt. Lassen and Mt. Shasta, near the town of Burney. Recent analyses indicate that this gap allows AR water vapor to penetrate into the western interior (e.g., to Idaho) and thus contribute to heavy precipitation events far inland. The CalWater-2 program of field campaigns has identified diagnosis of the transport through this gap and its impact on northern California precipitation as a priority for future data collection and analysis.

  8. Recent Advances in the Treatment of Organophosphorous Poisonings

    Directory of Open Access Journals (Sweden)

    Mahdi Balali-Mood

    2012-06-01

    Full Text Available Organophosphorous compounds have been employed as pesticides and chemical warfare nerve agents. Toxicity of organophosphorous compounds is a result of excessive cholinergic stimulation through inhibition of acetyl cholinesterase. Clinical manifestations include cholinergic syndromes, central nervous system and cardiovascular disorders. Organophosphorous pesticide poisonings are common in developing worlds including Iran and Sri Lanka. Nerve agents were used during the Iraq-Iran war in 1983-1988 and in a terrorist attack in Japan in 1994-1995. Following decontamination, depending on the severity of intoxication the administration of atropine to counteract muscarinic over-stimulation, and an oxime to reactivate acetyl cholinesterase are indicated. Supportive and intensive care therapy including diazepam to control convulsions and mechanical respiration may be required. Recent investigations have revealed that intravenous infusion of sodium bicarbonate to produce mild to moderate alkalinization is effective. Gacyclidine; an antiglutamatergic compound, was also proved to be beneficial in conjunction with atropine, pralidoxime, and diazepam in nerve agent poisoning. Intravenous magnesium sulfate decreased hospitalization duration and improved outcomes in patients with organophosphorous poisoning. Bio-scavengers including fresh frozen plasma or albumin have recently been suggested as a useful therapy through clearing of free organophosphates. Hemofiltration and antioxidants are also suggested for organophosphorous poisoning. Recombinant bacterial phosphotriesterases and hydrolases that are able to transfer organophosphorous-degrading enzymes are very promising in delayed treatment of organophosphorous poisoning. Recently, encapsulation of drugs or enzymes in nanocarriers has also been proposed. Given the signs and symptoms of organophosphorous poisoning, health professionals should remain updated about the recent advances in treatment of

  9. Alcohol Withdrawal Mimicking Organophosphate Poisoning

    Directory of Open Access Journals (Sweden)

    Nezihat Rana Disel

    2014-02-01

    Full Text Available Organophosphates, which can cause occupational poisoning due to inappropriate personal protective measures, are widely used insecticides in agricultural regions of southern Turkey. Therefore, the classical clinical findings of this cholinergic poisoning are myosis, excessive secretions, bradicardia and fasciculations are easy to be recognized by local medical stuff. Diseases and conditions related to alcoholism such as mental and social impairments, coma, toxicity, withdrawal, and delirium are frequent causes of emergency visits of chronic alcoholic patients. Here we present a case diagnosed and treated as organophosphate poisoning although it was an alcohol withdrawal in the beginning and became delirium tremens, due to similar symptoms.

  10. 76 FR 39357 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2011-07-06

    ... Pollution Control District, Kern County Air Pollution Control District, and Ventura County Air Pollution... proposing to approve revisions to the Imperial County Air Pollution Control District (ICAPCD), Kern County Air Pollution Control District (KCAPCD), and Ventura County Air Pollution Control District...

  11. Fatal aluminium phosphide poisoning

    Directory of Open Access Journals (Sweden)

    Meena Mahesh Chand

    2015-06-01

    Full Text Available Aluminium phosphide (AlP is a cheap solid fumigant and a highly toxic pesticide which is commonly used for grain preservation. AlP has currently aroused interest with a rising number of cases in the past four decades due to increased use for agricultural and non-agricultural purposes. Its easy availability in the markets has increased also its misuse for committing suicide. Phosphine inhibits cellular oxygen utilization and can induce lipid peroxidation. Poisoning with AlP has often occurred in attempts to commit suicide, and that more often in adults than in teenagers. This is a case of suicidal consumption of aluminium phosphide by a 32-year-old young medical anesthetist. Toxicological analyses detected aluminium phosphide. We believe that free access of celphos tablets in grain markets should be prohibited by law.

  12. [Ciguatera fish poisoning].

    Science.gov (United States)

    Oehler, Erwan; Bouchut, Jérémie

    2014-09-01

    Ciguatera, an ichtyosarcotoxism linked to the consumption of usually healthy coral fish is a common poisoning in the Pacific, Caribbean and Indian Ocean where it is endemic. However, increased tourism and commercial transportation of tropical fish for consumption make it an unexceptional intoxication in countries away from its endemic area. Environmental stresses such as climate changes also contribute to the expansion of its geographical area. The non-specific clinical symptomatology is characterized by the occurrence of gastrointestinal, cardiovascular, nervous and general signs few hours after eating a ciguatoxic fish. The diagnosis is clinical and relatively easy in endemic areas but much less for physicians who are rarely confronted with, which is a source of prolonged diagnostic delays and a significant increase in spending. Treatment of ciguatera is symptomatic but new treatments, still experimental, give a real hope for the future.

  13. 76 FR 28944 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-05-19

    ... Control District and Feather River Air Quality Management District AGENCY: Environmental Protection Agency... permitting rules submitted for the Placer County Air Pollution Control District (PCAPCD) and Feather River..., Air pollution control, Incorporation by reference, Intergovernmental relations, Ozone,...

  14. 76 FR 44809 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-07-27

    ... Air Pollution Control District and Feather River Air Quality Management District ACTION: Final rule... the Placer County Air Pollution Control District (PCAPCD) and Feather River Air Quality Management... CFR Part 52 Environmental protection, Air pollution control, Incorporation by...

  15. 75 FR 24544 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2010-05-05

    ... Control District, Sacramento Metropolitan Air Quality Management District, San Joaquin Valley Unified Air Pollution Control District, and South Coast Air Quality Management District AGENCY: Environmental Protection... Air Pollution Control District (PCAPCD), Sacramento Metropolitan Air Quality Management...

  16. 75 FR 24406 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2010-05-05

    ... Control District, Sacramento Metropolitan Air Quality Management District, San Joaquin Valley Unified Air Pollution Control District, and South Coast Air Quality Management District AGENCY: Environmental Protection... to the Placer County Air Pollution Control District (PCAPCD), Sacramento Metropolitan Air...

  17. 78 FR 12267 - Revision of Air Quality Implementation Plan; California; Placer County Air Pollution Control...

    Science.gov (United States)

    2013-02-22

    ... Pollution Control District and Feather River Air Quality Management District; Stationary Source Permits... County Air Pollution Control District (PCAPCD) and Feather River Air Quality Management District (FRAQMD... of Subjects in 40 CFR Part 52 Environmental protection, Air pollution control, Incorporation...

  18. Organophosphate Poisoning and Subsequent Acute Kidney Injury Risk: A Nationwide Population-Based Cohort Study.

    Science.gov (United States)

    Lee, Feng-You; Chen, Wei-Kung; Lin, Cheng-Li; Lai, Ching-Yuan; Wu, Yung-Shun; Lin, I-Ching; Kao, Chia-Hung

    2015-11-01

    Small numbers of the papers have studied the association between organophosphate (OP) poisoning and the subsequent acute kidney injury (AKI). Therefore, we used the National Health Insurance Research Database (NHIRD) to study whether patients with OP poisoning are associated with a higher risk to have subsequent AKI.The retrospective cohort study comprised patients aged ≥20 years with OP poisoning and hospitalized diagnosis during 2000-2011 (N = 8924). Each OP poisoning patient was frequency-matched to 4 control patients based on age, sex, index year, and comorbidities of diabetes, hypertension, hyperlipidemia, chronic obstructive pulmonary disease, coronary artery disease, and stroke (N = 35,696). We conducted Cox proportional hazard regression analysis to estimate the effects of OP poisoning on AKI risk.The overall incidence of AKI was higher in the patients with OP poisoning than in the controls (4.85 vs 3.47/1000 person-years). After adjustment for age, sex, comorbidity, and interaction terms, patients with OP poisoning were associated with a 6.17-fold higher risk of AKI compared with the comparison cohort. Patients with highly severe OP poisoning were associated with a substantially increased risk of AKI.The study found OP poisoning is associated with increased risk of subsequent AKI. Future studies are encouraged to evaluate whether long-term effects exist and the best guideline to prevent the continuously impaired renal function.

  19. Geologic and Anthropogenic Controls on Selenium and Nitrate Loading to Southern California Streams

    Science.gov (United States)

    Hibbs, B. J.; Ellis, A. S.

    2009-12-01

    concentrations of nitrate in leachate, possibly from accumulation from atmospheric fallout. Leachate from non-weathered Miocene rock generally had low nitrate concentrations and low selenium. Miocene shales are exposed in vast areas of Southern California. We are undertaking regional studies to determine if other Southern California Watersheds are affected by elevated nitrate and selenium concentrations, and where selenium may threaten habitat.

  20. 76 FR 39303 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2011-07-06

    ... Pollution Control District, Kern County Air Pollution Control District, and Ventura County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve revisions to the Imperial County Air Pollution Control...

  1. Neurotoxic shellfish poisoning: A review

    NARCIS (Netherlands)

    Apeldoorn ME van; Egmond HP van; Speijers GJA; CSR; ARO

    2001-01-01

    This review contains information on the neurotoxic shellfish poisoning (NSP) syndrome and the provoking toxins called brevetoxins, produced by the dinoflagellate Gymnodinium breve. Data on chemical structures and detection methods for brevetoxins, sources for brevetoxins, marine organisms associated

  2. Antidotes for acute cyanide poisoning.

    Science.gov (United States)

    Borron, Stephen W; Baud, Frederic J

    2012-08-01

    Cyanide poisoning can present in multiple ways, given its widespread industrial use, presence in combustion products, multiple physical forms, and chemical structures. The primary target of toxicity is mitochondrial cytochrome oxidase. The onset and severity of poisoning depend on the route, dose, physicochemical structure and other variables. Common poisoning features include dyspnea, altered respiratory patterns, abnormal vital signs, altered mental status, seizures, and lactic acidosis. Our present knowledge supports cyanide poisoning treatment based on excellent supportive care with adjunctive antidotal therapy. Multiple antidotes exist and vary in regional availability. All currently marketed antidotes appear to be effective. Antidotal mechanisms include chelation, formation of stable, less toxic complexes, methemoglobin induction, and sulfane sulfur supplementation for detoxification by endogenous rhodanese. Each antidote has advantages and disadvantages. For example, hydroxocobalamin is safer than the methemoglobin inducers in patients with smoke inhalation. Research for new, safer and more effective cyanide antidotes continues.

  3. Organophosphate Poisoning and Intermediate Syndrome

    Directory of Open Access Journals (Sweden)

    Mustafa Yilmaz

    2016-03-01

    Full Text Available Toxic effects that occur after acute organophosphate poisoning (OP can manifest three phases, namely, acute cholinergic crisis, intermediate syndrome and delayed-type polyneuropathy. Clinical signs and symptoms of organophosphate poisoning depend on the accumulation of acetylcholine at the nerve junction. Organophosphate poisoning causes three main clinical findings; acute cholinergic crisis consisting of muscarinic, nicotinic and central nervous system symptoms, intermediate syndrome with recurrence of cholinergic symptoms or muscle weakness without fasciculation 24-96 hours after poisoning and delayed-type polyneuropathy that can usually occur several days or weeks after acute exposure to organic phosphorus compounds. In this article, intermediate syndrome, which is a late complication, has been reviewed. [Archives Medical Review Journal 2016; 25(1.000: 70-83

  4. Grass and weed killer poisoning

    Science.gov (United States)

    ... medlineplus.gov/ency/article/002838.htm Grass and weed killer poisoning To use the sharing features on this page, please enable JavaScript. Many weed killers contain dangerous chemicals that are harmful if ...

  5. Alcohol Poisoning Deaths PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2015-01-06

    This 60 second Public Service Announcement is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.  Created: 1/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/6/2015.

  6. Joint environmental assessment 1997--2001 of the California Department of Food and Agriculture Curly Top Virus Control Program for Bureau of Land Management and Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The DOE, Naval Petroleum reserves in California (NPRC), proposes to sign an Amendment to the Cooperative Agreement and Supplement with the California Department of Food and Agriculture (CDFA) to extend the term of the Curly Top Virus Control Program (CTVCP) in California. This program involves Malathion spraying on NPRC lands to control the beet leafhopper, over a five year period from 1997 through 2001. It is expected that approximately 330 acres on Naval Petroleum Reserve Number 1 (NPR-1) and approximately 9,603 acres on Naval Petroleum Reserve Number 2 (NPR-2) will be treated with Malathion annually by CDFA during the course of this program. The actual acreage subject to treatment can vary from year to year. Pursuant to the requirements of the National Environmental Policy Act of 1969 (NEPA), as amended, the potential impacts of the proposed action were analyzed in a Joint Environmental Assessment (DOE/EA-1011) with the US Department of Interior, Bureau of Land Management (BLM) acting as lead agency, in consultation with the CDFA, and the DOE acting as a cooperating agency. Based on the analysis in the EA, DOE has determined that the conduct of the Curly Top Virus Control Program in California is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the NEPA. Therefore, the preparation of an Environmental Impact Statement is not required and DOE is consequently issuing a FONSI.

  7. Effects of site disturbance and vegetation control on aboveground biomass in young mixed-conifer plantations in California

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J.; Powers, R.; Fiddler, G. [United States Dept. of Agriculture Forest Service, CA (United States). California Long-Term Soil Productivity Experiment Steering Committee, Pacific Southwest Research Station; Young, D. [United States Dept. of Agriculture Forest Service, CA (United States). California Long-Term Soil Productivity Experiment Steering Committee, Shasta-Trinity National Forest; Roath, B.; Landram, M. [United States Dept. of Agriculture Forest Service, CA (United States). California Long-Term Soil Productivity Experiment Steering Committee, Pacific Southwest Region

    2010-07-01

    This study evaluated the effect of vegetation control and site disturbance on aboveground biomass in young conifer plantations in California. Ten-year vegetation data from 12 long-term soil productivity sites in the Sierra Nevada and southern Cascades were used to determine above ground biomass. In addition, 15-year vegetation data from 3 earlier Sierra Nevada sites was also examined. The aim of the study was to determine how biomass management impacts site productivity in the next generation of forest. The sites included 9 factorial combinations of 3 organic matter removals. Plots were planted with a mixture of conifers and divided into 2 subplots where understory vegetation was either controlled, or allowed to develop naturally. The study showed that neither the 10-year nor the 15-year total aboveground biomass was significantly impacted by organic matter removal. Results indicated that no negative effect of either organic matter removal or soil compaction on total aboveground biomass occurred in the early stages of stand development of mixed conifer plantations. However, understory control significantly decreased total site production as a result of delayed site occupancy.

  8. 76 FR 71886 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-11-21

    ... Control District and Sacramento Metropolitan Air Quality Management District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve revisions to the Placer County Air Pollution Control District (PCAPCD) and Sacramento Metropolitan...

  9. Interim animal control plan Modoc National Wildlife refuge Alturas California May 1970

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Management plan to reduce predation impact on refuge bird species. Document includes bird predator control, burrowing mammal control, purpose, species to be...

  10. 76 FR 67396 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2011-11-01

    ...). These revisions concern oxides of nitrogen (NO X ) emissions from industrial, institutional and... Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Placer County Air Pollution Control District (PCAPCD) and...

  11. California's 2002 Clean Water Act Section 303(d) - Impaired Waterbodies

    Data.gov (United States)

    California Department of Resources — This dataset contains California's 2002 Clean Water Act Section 303(d) list which is submitted by the California State Water Resources Control Board. The layer has...

  12. 78 FR 37130 - Revisions to the California State Implementation Plan, San Diego Air Pollution Control District

    Science.gov (United States)

    2013-06-20

    ... Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve a revision to the San Diego Air Pollution Control District (SDAPCD... environment. Section 110(a) of the CAA requires States to submit regulations that control VOC...

  13. 76 FR 30025 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-05-24

    ... Control District and Ventura County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve revisions to the Placer County Air Pollution Control District (PCAPCD) and Ventura County Air Pollution...

  14. 76 FR 75795 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2011-12-05

    ... Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve revisions to the Placer County Air Pollution Control District... the environment. Section 110(a) of the CAA requires States to submit regulations that control...

  15. 76 FR 60376 - Revisions to the California State Implementation Plan, Santa Barbara Air Pollution Control...

    Science.gov (United States)

    2011-09-29

    ... taking direct final action to approve revisions to the Santa Barbara Air Pollution Control District... Control District, Sacramento Municipal Air Quality Management District and South Coast Air Quality... the environment. Section 110(a) of the CAA requires States to submit regulations that control...

  16. 76 FR 5277 - Revisions to the California State Implementation Plan, Santa Barbara Air Pollution Control...

    Science.gov (United States)

    2011-01-31

    ... Control District, Antelope Valley Air Quality Management District, Ventura County Air Pollution Control District and Placer County Air Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action to approve revisions to the...

  17. 76 FR 40660 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

    Science.gov (United States)

    2011-07-11

    .... SUMMARY: EPA is proposing to approve revisions to the San Joaquin Valley Air Pollution Control District....0 for the following terms: Air Pollution Control Officer, Board, Environmental Protection Agency.... New Section 6.3 requires the SJVUAPCD Air Pollution Control Officer (APCO) to prepare and present...

  18. 75 FR 10690 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

    Science.gov (United States)

    2010-03-09

    ... is finalizing approval of revisions to the San Joaquin Valley Air Pollution Control District (SJVAPCD...)(2)). List of Subjects in 40 CFR Part 52 Environmental protection, Air pollution control... Joaquin Valley Unified Air Pollution Control District. (1) Rule 4104, ``Reduction of Animal Matter,''...

  19. 78 FR 6736 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2013-01-31

    ... taking direct final action to approve revisions to the Placer County Air Pollution Control District... regulations that control VOCs, NO X , and PM emissions. Rules 301-306 limit emissions of air pollutants... Toxic Control Measure to Reduce Emissions of Toxic Air Contaminants from Outdoor Residential...

  20. Large-Scale Aquifer Replenishment and Seawater Intrusion Control Using Recycled Water in Southern California

    Energy Technology Data Exchange (ETDEWEB)

    Herndon, R.; Markus, M.

    2014-10-01

    In 2008, eighteen years after determining that its Talbert Seawater Barrier required expansion, the Orange County Water District started up the worldss largest indirect potable reuse facility, the Groundwater Replenishment System (GWR System). The GWR System provides a reliable potable-quality water supply to the Talbert Barrier, which consists of 109 multi-depth injection wells. The Talbert Barrier began operation in 1976 with the completion of Water Factory 21, the first project in California permitted to inject recycled water into a potable-supply aquifer. By 1990, as groundwater pumping increased, it was evident that the barriers original injection wells were incapable of maintaining protective groundwater elevations to prevent seawater intrusion. Ten years of technical planning and public outreach culminated in the decision to demolish the undersized Water Factory 21 and build a state-of-the-art advanced recycled water treatment system and expanded barrier. Barrier expansion entailed construction of over 20 new injection wells in key areas where seawater intrusion was observed. Flow modeling indicated that average barrier injection needed to be doubled to 80 m{sup 3}/min (30 mgal/day). Based on seasonal groundwater pumping patterns, model simulations indicated that the barrier should inject up to 107 m{sup 3}/min (40 mgal/day) in the summer/fall months and one-half that rate in winter/spring months to maintain a protective hydraulic barrier. With a capacity of 187 m{sup 3}/min (70 mgd), the GWR System provides all of the high-quality water that the barrier requires, with the remainder conveyed to OCWDss infiltration basins in the city of Anaheim. Five years after start-up, the expanded seawater barrier has met all expectations in terms of capacity and groundwater elevation maintenance using a reliable locally-produced water supply. (Author)

  1. Researching nature's venoms and poisons.

    Science.gov (United States)

    Warrell, David A

    2009-09-01

    Our environment hosts a vast diversity of venomous and poisonous animals and plants. Clinical toxinology is devoted to understanding, preventing and treating their effects in humans and domestic animals. In Sri Lanka, yellow oleander (Thevetia peruviana, Sinhala 'kaneru'), a widespread and accessible ornamental shrub, is a popular means of self-harm. Its toxic glycosides resemble those of foxglove, against which therapeutic antibodies have been raised. A randomised placebo-controlled trial proved that this treatment effectively reversed kaneru cardiotoxicity. There are strong scientific grounds for the use of activated charcoal, but encouraging results with multiple-dose activated charcoal were not confirmed by a recent more powerful study. Venom of Russell's viper (Daboia siamensis) in Burma (Myanmar) produces lethal effects in human victims. The case of a 17-year-old rice farmer is described with pathophysiological interpretations. During the first 9 days of hospital admission he suffered episodes of shock, coagulopathy, bleeding, acute renal failure, local tissue necrosis, generally increased capillary permeability and acute symptomatic hypoglycaemia with evidence of acute pituitary/adrenal insufficiency. Antivenom rapidly restored haemostatic function but failed to correct other effects of venom toxins incurred during the 3h before he could be treated.

  2. Identification and treatment of poison ivy dermatitis.

    Science.gov (United States)

    Briant, D; Brouder, G

    1983-01-01

    Poison ivy dermatitis is an acute self-limiting problem of two or three weeks' duration that can cause significant discomfort. Poison ivy, poison oak and poison sumac cause more cases of allergic contact dermatitis than all the other contact allergens combined. Treatment of poison ivy dermatitis depends on the severity of the reaction. The nurse practitioner can manage the majority of poison ivy cases. However, if there is systemic involvement, a physician consultation is necessary. The patient can best be assisted by assessing the severity of the dermatitis, prescribing an appropriate supportive therapy and teaching preventive measures.

  3. Experimental lead poisoning in Turkey Vultures, Cathartes aura

    Science.gov (United States)

    Carpenter, J.W.; Pattee, O.H.; Fritts, S.H.; Rattner, B.A.; Wiemeyer, Stanley N.; Royle, J. Andrew; Smith, M.R.

    2003-01-01

    Lead-induced mortality appears to have been a major factor in the decline of the California condor, Gymnogyps californianus. We orally dosed turkey vultures (Cathartes aura) with BB-sized lead shot from January 1988 through July 1988 to determine physiological response (delta-aminolevulinic acid dehydratase inhibition, erythrocyte protoporphyrin levels, anemia), diagnostic tissue lead concentrations (blood, liver, and kidney), and comparative sensitivity of this species. Two turkey vultures died and two became so intoxicated they were euthanized. Overall, responses of measured parameters were comparable to other species exposed to lead although there was considerable individual variation. Survival time (143-211 days), even with the large number of shot and constant redosing, was much longer than reported for other species of birds, suggesting considerable tolerance by turkey vultures to the deleterious effects of lead ingestion. Based on these observations, turkey vultures appear to be poor models for assessing the risk of lead poisoning to California condors or predicting their physiological response.

  4. Neurotoxic Shellfish Poisoning

    Directory of Open Access Journals (Sweden)

    Roberta Hammond

    2008-07-01

    Full Text Available Neurotoxic shellfish poisoning (NSP is caused by consumption of molluscan shellfish contaminated with brevetoxins primarily produced by the dinoflagellate, Karenia brevis. Blooms of K. brevis, called Florida red tide, occur frequently along the Gulf of Mexico. Many shellfish beds in the US (and other nations are routinely monitored for presence of K. brevis and other brevetoxin-producing organisms. As a result, few NSP cases are reported annually from the US. However, infrequent larger outbreaks do occur. Cases are usually associated with recreationally-harvested shellfish collected during or post red tide blooms. Brevetoxins are neurotoxins which activate voltage-sensitive sodium channels causing sodium influx and nerve membrane depolarization. No fatalities have been reported, but hospitalizations occur. NSP involves a cluster of gastrointestinal and neurological symptoms: nausea and vomiting, paresthesias of the mouth, lips and tongue as well as distal paresthesias, ataxia, slurred speech and dizziness. Neurological symptoms can progress to partial paralysis; respiratory distress has been recorded. Recent research has implicated new species of harmful algal bloom organisms which produce brevetoxins, identified additional marine species which accumulate brevetoxins, and has provided additional information on the toxicity and analysis of brevetoxins. A review of the known epidemiology and recommendations for improved NSP prevention are presented.

  5. Optimal Environmental Conditions and Anomalous Ecosystem Responses: Constraining Bottom-up Controls of Phytoplankton Biomass in the California Current System

    Science.gov (United States)

    Jacox, Michael G.; Hazen, Elliott L.; Bograd, Steven J.

    2016-06-01

    In Eastern Boundary Current systems, wind-driven upwelling drives nutrient-rich water to the ocean surface, making these regions among the most productive on Earth. Regulation of productivity by changing wind and/or nutrient conditions can dramatically impact ecosystem functioning, though the mechanisms are not well understood beyond broad-scale relationships. Here, we explore bottom-up controls during the California Current System (CCS) upwelling season by quantifying the dependence of phytoplankton biomass (as indicated by satellite chlorophyll estimates) on two key environmental parameters: subsurface nitrate concentration and surface wind stress. In general, moderate winds and high nitrate concentrations yield maximal biomass near shore, while offshore biomass is positively correlated with subsurface nitrate concentration. However, due to nonlinear interactions between the influences of wind and nitrate, bottom-up control of phytoplankton cannot be described by either one alone, nor by a combined metric such as nitrate flux. We quantify optimal environmental conditions for phytoplankton, defined as the wind/nitrate space that maximizes chlorophyll concentration, and present a framework for evaluating ecosystem change relative to environmental drivers. The utility of this framework is demonstrated by (i) elucidating anomalous CCS responses in 1998-1999, 2002, and 2005, and (ii) providing a basis for assessing potential biological impacts of projected climate change.

  6. Chemical control of California arrowhead (Sagittaria montevidensis resistant to acetolactate synthase and photosystem II inhibiting herbicides in irrigated rice

    Directory of Open Access Journals (Sweden)

    Diogo da Silva Moura

    Full Text Available ABSTRACT: California arrowhead is one of the primary weeds infesting paddy rice fields in the Brazilian states of Santa Catarina and Rio Grande do Sul, where the system of pre-germinated seeding is used. The objective of this study was to evaluate the selectivity and effectiveness of saflufenacil application in irrigated rice, either singly or in combination with other herbicides in the same application or sequentially, for the control of Sagittaria montevidensis biotype that is resistant to ALSand PSII-inhibiting herbicides. In the first experiment carried out in a greenhouse, saflufenacil was applied, either singly or in combination with penoxsulam, bispyribac-sodium, pyrazosulfuron-ethyl, bentazon, or propanil to the S. montevidensis (SAGMO 32 biotype and the irrigated rice variety Epagri 108. In the second experiment, single or combined (including sequential applications of saflufenacil, bentazon, and cyhalofop-butyl were applied to Epagri 108 in open field conditions. Saflufenacil combined with propanil showed a high degree of phytotoxicity and a reduction in the accumulation of dry mass in Epagri 108. Application of saflufenacil, bentazon, and cyhalofop-butyl in combination or sequentially resulted in an increase in phytotoxicity in Epagri 108 compared to when applied singly. A pplication of saflufenacil singly or in combination with penoxsulam, bispyribac-sodium, bentazon, or pyrazosulfuron-ethyl did not adequately control SAGMO 32.

  7. Postharvest treatment of fresh fruit from California with methyl bromide for control of light brown apple moth (Lepidoptera: Tortricidae).

    Science.gov (United States)

    Walse, Spencer S; Myers, Scott W; Liu, Yong-Biao; Bellamy, David E; Obenland, David; Simmons, Greg S; Tebbets, Steve

    2013-06-01

    Methyl bromide (MB) chamber fumigations were evaluated for postharvest control of light brown apple moth, Epiphyas postvittana (Walker) (Lepidoptera: Tortricidae), in fresh fruit destined for export from California. To simulate external feeding, larvae were contained in gas-permeable cages and distributed throughout loads of peaches, plums, nectarines (all Prunus spp.), apples (Malus spp.), raspberries (Rubus spp.), or grapes (Vitis spp.). Varying the applied MB dose and the differential sorption of MB by the loads resulted in a range of exposures, expressed as concentration x time cross products (CTs) that were verified by gas-chromatographic quantification of MB in chamber headspace over the course of each fumigation. CTs > or = 60 and > or = 72 mg liter(-1) h at 10.0 +/- 0.5 and 15.6 +/- 0.5 degrees C (x +/- s, average +/- SD), respectively, yielded complete mortality of approximately 6,200 larvae at each temperature. These confirmatory fumigations corroborate E. postvittana mortality data for the first time in relation to measured MB exposures and collectively comprise the largest number of larval specimens tested to date. In addition, akinetic model of MB sorption was developed for the quarantine fumigation of fresh fruit based on the measurement of exposures and how they varied across the fumigation trials. The model describes how to manipulate the applied MB dose, the load factor, and the load geometry for different types of packaged fresh fruit so that the resultant exposure is adequate for insect control.

  8. Optimal Environmental Conditions and Anomalous Ecosystem Responses: Constraining Bottom-up Controls of Phytoplankton Biomass in the California Current System.

    Science.gov (United States)

    Jacox, Michael G; Hazen, Elliott L; Bograd, Steven J

    2016-06-09

    In Eastern Boundary Current systems, wind-driven upwelling drives nutrient-rich water to the ocean surface, making these regions among the most productive on Earth. Regulation of productivity by changing wind and/or nutrient conditions can dramatically impact ecosystem functioning, though the mechanisms are not well understood beyond broad-scale relationships. Here, we explore bottom-up controls during the California Current System (CCS) upwelling season by quantifying the dependence of phytoplankton biomass (as indicated by satellite chlorophyll estimates) on two key environmental parameters: subsurface nitrate concentration and surface wind stress. In general, moderate winds and high nitrate concentrations yield maximal biomass near shore, while offshore biomass is positively correlated with subsurface nitrate concentration. However, due to nonlinear interactions between the influences of wind and nitrate, bottom-up control of phytoplankton cannot be described by either one alone, nor by a combined metric such as nitrate flux. We quantify optimal environmental conditions for phytoplankton, defined as the wind/nitrate space that maximizes chlorophyll concentration, and present a framework for evaluating ecosystem change relative to environmental drivers. The utility of this framework is demonstrated by (i) elucidating anomalous CCS responses in 1998-1999, 2002, and 2005, and (ii) providing a basis for assessing potential biological impacts of projected climate change.

  9. 75 FR 27975 - Revisions to the California State Implementation Plan; Imperial County Air Pollution Control...

    Science.gov (United States)

    2010-05-19

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Imperial County Air Pollution Control District (ICAPCD... Clean Air Act as amended in 1990 (CAA or the Act). We are taking comments on this proposal and plan...

  10. 76 FR 7142 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2011-02-09

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Imperial County Air Pollution Control District (ICAPCD... pollution sources. We are taking comments on this proposal and plan to follow with a final action....

  11. 77 FR 25109 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2012-04-27

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Imperial County Air Pollution Control District (ICAPCD...). We are taking comments on this proposal and plan to follow with a final action. DATES: Any...

  12. 76 FR 67366 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control...

    Science.gov (United States)

    2011-11-01

    .... ``Alternative Control Techniques Document--NO X Emissions from Industrial/Commercial/Institutional (ICI) Boilers... concern oxides of nitrogen (NO X ) emissions from industrial, institutional and commercial boilers... requires States to submit regulations that control NO X emissions. Rule 231 limits emission of NO X...

  13. 78 FR 23677 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2013-04-22

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is finalizing approval of revisions to the Imperial County Air Pollution Control District (ICAPCD...) emissions from sources of fugitive dust such as unpaved roads and disturbed soils in open and...

  14. 78 FR 922 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2013-01-07

    ... Pollution Control District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Imperial County Air Pollution Control District (ICAPCD... disturbed soils in open and agricultural areas in Imperial County. We are proposing to approve local...

  15. 75 FR 2796 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

    Science.gov (United States)

    2010-01-19

    ... limit use VOC capture and control systems.\\11\\ Given the commenter has provided no information to... Board's 2005 Suggested Control Measures for Automotive Coatings (CARB 2005 SCM), which includes ``precoat'' coatings in the ``primer'' category.\\15\\ The 2005 CARB SCM recommends a VOC limit of 250 g/L...

  16. 75 FR 39365 - Revisions to the California State Implementation Plan, Imperial County Air Pollution Control...

    Science.gov (United States)

    2010-07-08

    ... County, and notes that BLM previously estimated PM 10 impacts from OHV activities at the Aldodones Dunes... temporally for purposes of modeling air pollution impacts and developing cost effective control programs....

  17. The Pittsburgh Poison Center profile of an American poison information center.

    Science.gov (United States)

    Krenzelok, Edward P

    2005-01-01

    The Pittsburgh Poison Center (PPC), a department of Children's Hospital of Pittsburgh, was established in 1971 to provide emergency poison information to the residents of western Pennsylvania, especially the children. The PPC provides comprehensive poison information center services to the lay public and to medical professionals, poison prevention education, professional education and specialized services to the business and industry sector and governmental agencies.

  18. Organophosphorus pesticide poisoning : cases and developments

    NARCIS (Netherlands)

    Aardema, H.; Ligtenberg, J. J. M.; Peters-Polman, O. M.; Tulleken, J. E.; Zijlstra, J. G.; Meertens, John H. J. M.

    2008-01-01

    Self-poisoning with organophosphate pesticides is a major health problem world-wide. Through the inhibition of acetylcholinesterase, organophosphorus poisoning is characterised by the clinical picture of acute cholinergic crisis. Other manifestations are the intermediate neurotoxic syndrome and dela

  19. Poison ivy on the leg (image)

    Science.gov (United States)

    This is a typical early appearance of a poison ivy rash, located on the leg. These early lesions ... line where the skin has brushed against the poison ivy plant. The rash is caused by skin contact ...

  20. 49 CFR 172.430 - POISON label.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON label. 172.430 Section 172.430... SECURITY PLANS Labeling § 172.430 POISON label. (a) Except for size and color, the POISON label must be as follows: EC02MR91.029 (b) In addition to complying with § 172.407, the background on the POISON label...

  1. Extracorporeal Treatment for Metformin Poisoning

    DEFF Research Database (Denmark)

    Calello, Diane P; Liu, Kathleen D; Wiegand, Timothy J;

    2015-01-01

    diverse professions, presents its systematic review and clinical recommendations for extracorporeal treatment in metformin poisoning. METHODS: A systematic literature search was performed, data extracted, findings summarized, and structured voting statements developed. A two-round modified Delphi method......BACKGROUND: Metformin toxicity, a challenging clinical entity, is associated with a mortality of 30%. The role of extracorporeal treatments such as hemodialysis is poorly defined at present. Here, the Extracorporeal Treatments In Poisoning workgroup, comprising international experts representing......) and made the following recommendations: extracorporeal treatment is recommended in severe metformin poisoning (1D). Indications for extracorporeal treatment include lactate concentration greater than 20 mmol/L (1D), pH less than or equal to 7.0 (1D), shock (1D), failure of standard supportive measures (1D...

  2. Extracorporeal treatment for barbiturate poisoning

    DEFF Research Database (Denmark)

    Mactier, Robert; Laliberté, Martin; Mardini, Joelle;

    2014-01-01

    The EXTRIP (Extracorporeal Treatments in Poisoning) Workgroup conducted a systematic review of barbiturate poisoning using a standardized evidence-based process to provide recommendations on the use of extracorporeal treatment (ECTR) in patients with barbiturate poisoning. The authors reviewed all...... articles, extracted data, summarized key findings, and proposed structured voting statements following a predetermined format. A 2-round modified Delphi method was used to reach a consensus on voting statements, and the RAND/UCLA Appropriateness Method was used to quantify disagreement. 617 articles met...... depression necessitating mechanical ventilation, shock, persistent toxicity, or increasing or persistently elevated serum barbiturate concentrations despite treatment with multiple-dose activated charcoal. (3) Intermittent hemodialysis is the preferred mode of ECTR, and multiple-dose activated charcoal...

  3. Poisonous birds: A timely review.

    Science.gov (United States)

    Ligabue-Braun, Rodrigo; Carlini, Célia Regina

    2015-06-01

    Until very recently, toxicity was not considered a trait observed in birds, but works published in the last two decades started to shed light on this subject. Poisonous birds are rare (or little studied), and comprise Pitohui and Ifrita birds from Papua New Guinea, the European quail, the Spoor-winged goose, the Hoopees, the North American Ruffed grouse, the Bronzewings, and the Red warbler. A hundred more species are considered unpalatable or malodorous to humans and other animals. The present review intends to present the current understanding of bird toxicity, possibly pointing to an ignored research field. Whenever possible, biochemical characteristics of these poisons and their effects on humans and other animals are discussed, along with historical aspects of poison discovery and evolutionary hypothesis regarding their function.

  4. Biophysical controls on interannual variability in ecosystem-scale CO2 and CH4 exchange in a California rice paddy

    Science.gov (United States)

    Knox, Sara Helen; Matthes, Jaclyn Hatala; Sturtevant, Cove; Oikawa, Patricia Y.; Verfaillie, Joseph; Baldocchi, Dennis

    2016-03-01

    We present 6.5 years of eddy covariance measurements of fluxes of methane (FCH4) and carbon dioxide (FCO2) from a flooded rice paddy in Northern California, USA. A pronounced warming trend throughout the study associated with drought and record high temperatures strongly influenced carbon (C) budgets and provided insights into biophysical controls of FCO2 and FCH4. Wavelet analysis indicated that photosynthesis (gross ecosystem production, GEP) induced the diel pattern in FCH4, but soil temperature (Ts) modulated its amplitude. Forward stepwise linear models and neural networking modeling were used to assess the variables regulating seasonal FCH4. As expected due to their competence in modeling nonlinear relationships, neural network models explained considerably more of the variance in daily average FCH4 than linear models. During the growing season, GEP and water levels typically explained most of the variance in daily average FCH4. However, Ts explained much of the interannual variability in annual and growing season CH4 sums. Higher Ts also increased the annual and growing season ratio of FCH4 to GEP. The observation that the FCH4 to GEP ratio scales predictably with Ts may help improve global estimates of FCH4 from rice agriculture. Additionally, Ts strongly influenced ecosystem respiration, resulting in large interannual variability in the net C budget at the paddy, emphasizing the need for long-term measurements particularly under changing climatic conditions.

  5. [Venomous and poisonous animals. V. Envenomations by venomous marine invertebrates].

    Science.gov (United States)

    Bédry, R; de Haro, L

    2007-06-01

    Epidemiological information about marine envenomation is generally less extensive in Europe than in tropical countries where this type of injury is more severe and the need for medical attention is more frequent. For this reason use of the regional poison control centers in the areas where envenomation occurs must be encouraged. The purpose of this review is to describe envenomation by poisonous marine invertebrates (cephalopods, sea urchins, cone shells, jellyfish, anemones, star-fish, corals, and worms). Understanding of these envenomation syndromes is important not only in tropical areas but also in Europe where importation of dangerous species has increased in recent years.

  6. [Venomous and poisonous animals. IV. Envenomations by venomous aquatic vertebrates].

    Science.gov (United States)

    Bédry, R; De Haro, L

    2007-04-01

    Epidemiological information on marine envenomation is generally less extensive in Europe than in tropical regions where these injuries are more severe and the need for medical advice is more frequent. For these reasons use of regional Poison Control Centers in the area where the injury occurs must be encouraged. The purpose of this review is to describe envenomation by bony fish (lion fish, stone fish, and catfish), cartilaginous fish (stingrays and poisonous sharks), or other venomous aquatic vertebrates (moray-eels and marine snakes). Understanding of these envenomation syndromes is important not only in tropical areas but also in Europe where importation of dangerous species has increased in recent years.

  7. The role of serum cholinesterase activity and S100B protein in the evaluation of organophosphate poisoning.

    Science.gov (United States)

    Yardan, T; Baydin, A; Acar, E; Ulger, F; Aygun, D; Duzgun, A; Nar, R

    2013-10-01

    The aim of this study was to investigate the role of serum cholinesterase (SChE) activity and S100B protein in the evaluation of patients with acute organophosphate (OP) poisoning. Patients with acute OP poisoning admitted to the emergency department were included in this cross-sectional study. Twenty healthy volunteers served as controls. The SChE activity and serum S100B were determined on admission. Patients were divided into two groups (low severity and high severity). Thirty-six patients diagnosed with acute OP poisoning were enrolled. Serum S100B concentrations were higher in patients than in the control group (p poisoning.

  8. Poisonings and clinical toxicology: a template for Ireland.

    LENUS (Irish Health Repository)

    Tormey, W P

    2013-03-01

    Poisons information is accessed around the clock in the British Isles from six centres of which two are in Ireland at Dublin and Belfast accompanied by consultant toxicologist advisory service. The numbers of calls in Ireland are down to about 40 per day due to easy access to online data bases. Access to Toxbase, the clinical toxicology database of the National Poisons Information Service is available to National Health Service (NHS) health professionals and to Emergency Departments and Intensive Care units in the Republic of Ireland. There are 59 Toxbase users in the Republic of Ireland and 99 % of activity originates in Emergency Departments. All United States Poison Control Centres primarily use Poisindex which is a commercial database from Thomson Reuters.

  9. National Poison Prevention Week Promotional Materials.

    Science.gov (United States)

    Poison Prevention Week Council, Washington, DC.

    This collection of materials for parents, early childhood workers, the elderly, and anyone in situations requiring safeguards against poisoning, spans the years 1993 and 1994 and is intended to promote National Poison Prevention Week. The materials included are: (1) the 31-page, illustrated report on National Poison Prevention Week for 1993,…

  10. 49 CFR 172.554 - POISON placard.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON placard. 172.554 Section 172.554... SECURITY PLANS Placarding § 172.554 POISON placard. (a) Except for size and color, the POISON placard must be as follows: EC02MR91.057 (b) In addition to complying with § 172.519, the background on the...

  11. Is Your Child Safe from Lead Poisoning?

    Centers for Disease Control (CDC) Podcasts

    2008-10-02

    In this podcast, Dr. Mary Jean Brown, chief of CDC's Lead Poisoning and Prevention Program, discusses the importance of testing children for lead poisoning, who should be tested, and what parents can do to prevent lead poisoning.  Created: 10/2/2008 by National Center for Environmental Health (NCEH).   Date Released: 10/2/2008.

  12. 75 FR 56889 - Revisions to the California State Implementation Plan, San Diego County Air Pollution Control...

    Science.gov (United States)

    2010-09-17

    ...: EPA is taking direct final action to approve revisions to the San Diego County Air Pollution Control... high and adverse human health or environmental effects of their programs, policies, and activities on..., disproportionate human health or environmental effects, using practicable and legally permissible methods,...

  13. 76 FR 31242 - Revisions to the California State Implementation Plan, Santa Barbara County Air Pollution Control...

    Science.gov (United States)

    2011-05-31

    ... from boilers, steam generators and process heaters with a rated heat input rate greater than 2 million... Boilers, Steam 01/17/08 07/18/08 Generators and Process Heaters. SBCAPCD 333 Control of Emissions 06/19/08... District. (1) Rule 361, ``Small Boilers, Steam Generators and Process Heaters,'' adopted on January...

  14. Status of biological control projects on terrestrial invasive alien weeds in California

    Science.gov (United States)

    In cooperation with foreign scientists, we are currently developing new classical biological control agents for five species of invasive alien terrestrial weeds. Cape-Ivy. A gall-forming fly, Parafreutreta regalis, and a stem-boring moth, Digitivalva delaireae, have been favorably reviewed by TAG...

  15. 76 FR 5586 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo...

    Science.gov (United States)

    2011-02-01

    ... Equipment). CARB's Mobile Cargo Handling Equipment requirements are designed to use best available control... Alexander at (202) 343-9540, to learn if a hearing will be held or may check the following webpage for an... restricted by statute. EPA's Office of Transportation and Air Quality also maintains a webpage that...

  16. Recent progress in a classical biological control program for olive fruit fly in California

    Science.gov (United States)

    The olive fruit fly, Bactrocera oleae (Diptera: Tephritidae), causes severe damage to olive production worldwide. Control of olive fruit fly typically relies on pesticides, and under such conditions the impact of natural enemies is relatively low. About 15 years ago, the USDA-ARS European Biologic...

  17. California Air Basins

    Data.gov (United States)

    California Department of Resources — Air ResourcesCalifornia Air Resources BoardThe following datasets are from the California Air Resources Board: * arb_california_airbasins - California Air BasinsThe...

  18. Mercury poisoning: a diagnostic challenge.

    Science.gov (United States)

    Tezer, Hasan; Kaya, Aysenur; Kalkan, Gokhan; Erkocoglu, Mustafa; Ozturk, Kubra; Buyuktasli, Muge

    2012-11-01

    Clinical features of mercury poisoning are nonspecific, and a detailed history is very valuable. The silvery, shiny appearance of mercury makes it very exciting and attractive for children. The overall half-life of elemental mercury in the body averages approximately 2 months. Chelation therapy with dimercaptosuccinic acid is the treatment of choice if the urine or blood level of mercury is high or the symptoms are profound. Here, we describe a 14-year-old boy with fever, respiratory distress, and body rash. Investigation leading to a diagnosis of mercury poisoning was made only after his mother presented with the similar symptoms a few days later.

  19. Extracorporeal Treatment in Phenytoin Poisoning

    DEFF Research Database (Denmark)

    Anseeuw, Kurt; Mowry, James B; Burdmann, Emmanuel A;

    2016-01-01

    The Extracorporeal Treatments in Poisoning (EXTRIP) Workgroup conducted a systematic literature review using a standardized process to develop evidence-based recommendations on the use of extracorporeal treatment (ECTR) in patients with phenytoin poisoning. The authors reviewed all articles......, extracted data, summarized findings, and proposed structured voting statements following a predetermined format. A 2-round modified Delphi method was used to reach a consensus on voting statements, and the RAND/UCLA Appropriateness Method was used to quantify disagreement. 51 articles met the inclusion...

  20. Extracorporeal treatment for digoxin poisoning

    DEFF Research Database (Denmark)

    Mowry, James B; Burdmann, Emmanuel A; Anseeuw, Kurt;

    2016-01-01

    BACKGROUND: The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatments (ECTR) in poisoning. Here, we present our results for digoxin. METHODS: After a systematic literature search, clinical and toxicokinetic data were...... extracted and summarized following a predetermined format. The entire workgroup voted through a two-round modified Delphi method to reach a consensus on voting statements. A RAND/UCLA Appropriateness Method was used to quantify disagreement, and anonymous votes were compiled and discussed in person...

  1. Extracorporeal treatment for theophylline poisoning

    DEFF Research Database (Denmark)

    Ghannoum, Marc; Wiegand, Timothy J; Liu, Kathleen D;

    2015-01-01

    BACKGROUND: The Extracorporeal Treatments in Poisoning workgroup was created to provide evidence-based recommendations on the use of extracorporeal treatments (ECTRs) in poisoning. Here, the workgroup presents its systematic review and recommendations for theophylline. METHODS: After a systematic...... review of the literature, a subgroup reviewed articles, extracted data, summarized findings, and proposed structured voting statements following a pre-determined format. A two-round modified Delphi method was chosen to reach a consensus on voting statements and the RAND/UCLA Appropriateness Method...

  2. Controlling for race/ethnicity: a comparison of California commercial health plans CAHPS scores to NCBD benchmarks

    Directory of Open Access Journals (Sweden)

    Lopez Rebeca A

    2010-01-01

    Full Text Available Abstract Background Because California has higher managed care penetration and the race/ethnicity of Californians differs from the rest of the United States, we tested the hypothesis that California's lower health plan Consumer Assessment of Healthcare Providers and Systems (CAHPS® survey results are attributable to the state's racial/ethnic composition. Methods California CAHPS survey responses for commercial health plans were compared to national responses for five selected measures: three global ratings of doctor, health plan and health care, and two composite scores regarding doctor communication and staff courtesy, respect, and helpfulness. We used the 2005 National CAHPS 3.0 Benchmarking Database to assess patient experiences of care. Multiple stepwise logistic regression was used to see if patient experience ratings based on CAHPS responses in California commercial health plans differed from all other states combined. Results CAHPS patient experience responses in California were not significantly different than the rest of the nation after adjusting for age, general health rating, individual health plan, education, time in health plan, race/ethnicity, and gender. Both California and national patient experience scores varied by race/ethnicity. In both California and the rest of the nation Blacks tended to be more satisfied, while Asians were less satisfied. Conclusions California commercial health plan enrollees rate their experiences of care similarly to enrollees in the rest of the nation when seven different variables including race/ethnicity are considered. These findings support accounting for more than just age, gender and general health rating before comparing health plans from one state to another. Reporting on race/ethnicity disparities in member experiences of care could raise awareness and increase accountability for reducing these racial and ethnic disparities.

  3. Species biology and potential for controlling four exotic plants (Ammophila arenaria, Carpobrotus edulis, Cortaderia jubata and Gasoul crystallinum) on Vandenberg Air Force Base, California

    Science.gov (United States)

    Schmalzer, Paul A.; Hinkle, C. Ross

    1987-01-01

    Invasive exotic plants can displace native flora and modify community and ecosystem structure and function. Ammophila arenaria, Corpobrotus edulis, Cortaderia jubata, and Gasoul crystallinum are invasive plants present on Vandenberg Air Force Base, California, designated for study by the Environmental Task Force because of the perceived threat they represent to the native flora. Each plant's native habitat, how they came to be at Vandenberg, their propagation, and how they can be controlled is discussed.

  4. [Ergotamine poisoning: a case study].

    Science.gov (United States)

    Zapalska-Pozarowska, Karolina; Szponar, Jarosław; Górska, Agnieszka; Niewiedzioł, Marek

    2012-01-01

    Ergotamine is a well known pharmacological remedy applied in neurology (treatment of vascular headache) and in obstetrics (abortive remedy, uterus atony). But today it is rarely used, because of new safer anti-migraine medicine (triptanes) which cause fewer side effects. According to obstetrical indications ergotamine is applied only in hospital treatment. For that reason, cases of intoxication by this class of drugs are rarely observed. Ergotamine causes constriction of the blood vessels through the blockade of alpha-receptors and stimulation of the serotonin-receptors on the walls of blood vessels both in the central nervous system and in peripheral circulation. Intoxication/overdose symptoms may appear on application of therapeutic dose by sensitive patients, mostly by patients with migraine headache using ergotamine preparation for relief of migraine attacks. In the Regional Centre of Clinical Toxicology, a 21-year-old patient was hospitalized. She took about 20 tablets of Cafergot (complex preparation containing 1mg ergotamine tartare and 100mg caffeine). During her stay on the ward, typical symptoms of severe poisoning were observed: nausea, severe vomiting, dizziness, decreased blood pressure without perceptible pulse, narrowing of the blood vessels in the extremities of the body (peripheral vasoconstriction) - paresthesia, digital cyanosis, refrigeration of legs, angina. Due to taking once of a great dose of the drug by the patient, violent process of intoxication, possibility of dangerous complication and also the unavailability of specific antidotes and lack of efficient methods of extracorporeal elimination of the drug, the patient was intensively controlled and symptomatic treatments according to the law of intensive therapy was applied.

  5. Relationship Between Acute Benzodiazepine Poisoning and Acute Pancreatitis Risk: A Population-Based Cohort Study.

    Science.gov (United States)

    Liaw, Geng-Wang; Hung, Dong-Zong; Chen, Wei-Kung; Lin, Cheng-Li; Lin, I-Ching; Kao, Chia-Hung

    2015-12-01

    We designed a population-based retrospective cohort study to investigate the association between the event of benzodiazepine (BZD) poisoning and the risk of acute pancreatitis.In the present study, 12,893 patients with BZD poisoning during 2000 to 2011 were enrolled and matched with 4 comparison patients according to mean age and sex. We determined the cumulative incidences and adjusted hazard ratios of acute pancreatitis.A significant association was observed between BZD poisoning and acute pancreatitis. After adjustment for potential risk factors, the patients with BZD poisoning had a 5.33-fold increased risk of acute pancreatitis compared with the controls without BZD poisoning (HR = 5.33, 95% CI = 2.26-12.60). The results revealed that acute pancreatitis in patients with BZD poisoning occurred in a follow-up time of ≤1 month (HR = 50.0, P risk of acute pancreatitis was no different between the patients with and without BZD poisoning when the follow-up time was >1 month (HR = 1.07, P > .05).This population-based study revealed the positive correlation between the event of BZD poisoning and an increased risk of acute pancreatitis. The findings warrant further large-scale and in-depth investigation.

  6. Poisonings Associated with Intubation: US National Poison Data System Exposures 2000-2013.

    Science.gov (United States)

    Beauchamp, G A; Giffin, S L; Horowitz, B Z; Laurie, A L; Fu, R; Hendrickson, R G

    2016-06-01

    Patients may be intubated after exposure to a variety of substances because of respiratory failure, CNS sedation, pulmonary pathology, or cardiovascular instability. However, there is little data describing the types of substances that are associated with endotracheal intubation or the rates of intubation after these exposures. Evaluation of this association may inform future research on intubation after exposures to specific substances and guide poison prevention education. Our objective was to determine which exposures were commonly associated with intubation using the data from National Poison Data System (NPDS). The NPDS tracks data from potential exposures to substances reported to all American Association of Poison Control Centers. We performed a retrospective analysis of NPDS data from January 1st, 2000 to December 31st, 2013 to identify human exposures to substances that were associated with endotracheal intubation. Descriptive statistics were used to analyze the data. There were 93,474 single substance exposures and 228,507 multiple substance exposures that were associated with intubation. The most common exposures to substances that were associated with intubation were atypical antipsychotics (7.4 %) for single exposures and benzodiazepines (27.4 %) for multiple exposures. Within each age group, the most common known exposures to substances were for patients under 6 years, clonidine for single and multiple exposures; for patients aged 6-12 years, clonidine for single exposures and atypical antipsychotics for multiple exposures; for patients aged 13-19 years, atypical antipsychotics for single and multiple exposures; and for patients over 19 years, atypical antipsychotics for single exposures and benzodiazepines for multiple exposures. From 2000-2013, the exposures to substances most commonly associated with intubation varied by single versus multiple exposures and by age. This study helps clarify the exposures to substances that are associated with

  7. Pulmonary edema in acute carbon monoxide poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kun Sang; Chang, Kee Hyun; Lee, Myung Uk [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1974-10-15

    Acute carbon monoxide poisoning has frequently occurred in Korean, because of the coal briquette being widely used as fuel in Korean residences. Carbon monoxide poisoning has been extensively studied, but it has been sparsely reported that pulmonary edema may develop in acute CO poisoning. We have noticed nine cases of pulmonary edema in acute CO poisoning last year. Other possible causes of pulmonary edema could be exclude in all cases but one. The purpose of this paper is to describe nine cases of pulmonary edema complicated in acute CO poisoning and discuss the pathogenesis and the prognosis.

  8. Maximizing the Impact of Digital Media Campaigns to Promote Smoking Cessation: A Case Study of the California Tobacco Control Program and the California Smokers' Helpline.

    Science.gov (United States)

    Lee, Youn Ok; Momin, Behnoosh; Hansen, Heather; Duke, Jennifer; Harms, Kristin; McCartney, Amanda; Neri, Antonio; Kahende, Jennifer; Zhang, Lei; Stewart, Sherri L

    2014-01-01

    Digital media are often used to encourage smoking cessation by increasing quitline call volume through direct promotion to smokers or indirect promotion to smoker proxies. The documentation of a program's experiences utilizing digital media is necessary to develop both the knowledge base and a set of best practices. This case study highlights the use of digital media in a proxy-targeted campaign to promote the California Smokers' Helpline to health care professionals from October 2009 to September 2012. We describe the iterative development of the campaign's digital media activities and report campaign summaries of web metrics (website visits, webinar registrations, downloads of online materials, online orders for promotional materials) and media buy (gross impressions) tracking data. The campaign generated more than 2.7 million gross impressions from digital media sources over 3 years. Online orders for promotional materials increased almost 40% over the course of the campaign. A clearly defined campaign strategy ensured that there was a systematic approach in developing and implementing campaign activities and ensuring that lessons learned from previous years were incorporated. Discussion includes lessons learned and recommendations for future improvements reported by campaign staff to inform similar efforts using digital media.

  9. Model Predictive Control of HVAC Systems: Implementation and Testing at the University of California, Merced

    Energy Technology Data Exchange (ETDEWEB)

    Haves, Phillip; Hencey, Brandon; Borrell, Francesco; Elliot, John; Ma, Yudong; Coffey, Brian; Bengea, Sorin; Wetter, Michael

    2010-06-29

    A Model Predictive Control algorithm was developed for the UC Merced campus chilled water plant. Model predictive control (MPC) is an advanced control technology that has proven successful in the chemical process industry and other industries. The main goal of the research was to demonstrate the practical and commercial viability of MPC for optimization of building energy systems. The control algorithms were developed and implemented in MATLAB, allowing for rapid development, performance, and robustness assessment. The UC Merced chilled water plant includes three water-cooled chillers and a two million gallon chilled water storage tank. The tank is charged during the night to minimize on-peak electricity consumption and take advantage of the lower ambient wet bulb temperature. The control algorithms determined the optimal chilled water plant operation including chilled water supply (CHWS) temperature set-point, condenser water supply (CWS) temperature set-point and the charging start and stop times to minimize a cost function that includes energy consumption and peak electrical demand over a 3-day prediction horizon. A detailed model of the chilled water plant and simplified models of the buildings served by the plant were developed using the equation-based modeling language Modelica. Steady state models of the chillers, cooling towers and pumps were developed, based on manufacturers performance data, and calibrated using measured data collected and archived by the control system. A detailed dynamic model of the chilled water storage tank was also developed and calibrated. Simple, semi-empirical models were developed to predict the temperature and flow rate of the chilled water returning to the plant from the buildings. These models were then combined and simplified for use in a model predictive control algorithm that determines the optimal chiller start and stop times and set-points for the condenser water temperature and the chilled water supply temperature. The

  10. Control strategies for the reduction of airborne particulate nitrate in California's San Joaquin Valley

    Science.gov (United States)

    Kleeman, Michael J.; Ying, Qi; Kaduwela, Ajith

    The effect of NO x, volatile organic compound (VOC), and NH 3 emissions control programs on the formation of particulate ammonium nitrate in the San Joaquin Valley (SJV) was examined under the typical winter conditions that existed on 4-6 January, 1996. The UCD/CIT photochemical transport model was used for this study so that the source origin of primary particulate matter and secondary particulate matter could be identified. When averaged across the entire SJV, the model results predict that 13-18% of the reactive nitrogen (NO y=NO x+reaction products of NO x) emitted from local sources within the SJV was converted to nitrate at the ground level. Each gram of NO x emitted locally within the SJV (expressed as NO 2) produced 0.23-0.31 g of particulate ammonium nitrate (NH 4NO 3), which is much smaller than the maximum theoretical yield of 1.7 g of NH 4NO 3 per gram of NO 2. The fraction of reactive nitrogen converted to nitrate varied strongly as a function of location. Urban regions with large amounts of fresh NO emissions converted little reactive nitrogen to nitrate, while remote areas had up to 70% conversion (equivalent to approximately 1.2 g of NH 4NO 3 per gram of NO 2). The use of a single spatially averaged ratio of NH 4NO 3/NO x as a predictor of how changes to NO x emissions would affect particulate nitrate concentrations would not be accurate at all locations in the SJV under the conditions studied. The largest local sources of particulate nitrate in the SJV were predicted to be diesel engines and catalyst equipped gasoline engines under the conditions experienced on 6 January, 1996. Together, these sources accounted for less than half of the ground-level nitrate aerosol in the SJV. The remaining fraction of the aerosol nitrate originated from reactive nitrogen originally released upwind of the SJV. The majority of this upwind reactive nitrogen was already transformed to nitrate by the time it entered the SJV. The effect of local emissions controls on

  11. Immunologic studies of poisonous Anacardiaceae: I. Production of tolerance and desensitization to poison Ivy and oak urushiols using esterified urushiol derivatives in guinea pigs.

    Science.gov (United States)

    Watson, E S; Murphy, J C; Wirth, P W; Waller, C W; Elsohly, M A

    1981-03-01

    The development of contact sensitivity to poison ivy urushiol in Hartley guinea pigs was inhibited by i.v. injection of the diacetate esters of poison ivy and oak urushiols into guinea pigs 2 weeks prior to attempted sensitization with homologous antigen. Immune tolerance to urushiols of poison ivy and oak developed in 80% or more of the treated animals and persisted for the duration of the study, 8 weeks. The tolerance was immunologically specific for urushiols since the tolerant animals were sensitizable to the unrelated sensitizer 2, 4-dinitrochlorobenzene. Guinea pigs already sensitive to urushiol were also desensitized or hyposensitizied by i.v. injection of urushiol acetates in successively increasing doses. After receiving the equivalent of 16 mg of poison ivy and oak urushiols in the acetate form over a period of 12 weeks, 54% of a group of guinea pigs were desensitized to poison ivy. all of the remaining 46% of the guinea pigs still sensitive to poison ivy were substantially hyposensitized (no longer responded to 1.5 or 0.80 microgram test doses of PDC). A control group of guinea pigs was not hyposensitized by injection of vehicle, and remained highly sensitive throughout the 15 week study. The majority of treated animals (less than 80%) were also hyposensitized to poison sumac and cashew nut shell liquid allergens.

  12. [Preventive measures of food poisoning at care facilities for the elderly--current status and problems in food poisoning by noroviruses].

    Science.gov (United States)

    Ezoe, Kumiko; Nagatomi, Hideki; Imaizumi, Iwao

    2012-08-01

    Food poisoning at care facilities for the elderly has been breaking out approximately ten cases per year nationwide from 2001 to 2010. Especially, it reflected the characteristics of food poisoning caused by noroviruses at a high rate. Usually we have been preventing from food poisoning by noroviruses working on existing measures such as temperature control of food materials, sanitary handlings of cooking tools and table wares, and so on. Additionally, the most effective measures to avoid secondary pollution at care facilities for the elderly is that all members at these facilities have to have a sense of crisis about food poisoning by noroviruses and managers at these facilities must take care of health control for all staff.

  13. Extracorporeal treatment for acetaminophen poisoning

    DEFF Research Database (Denmark)

    Gosselin, S; Juurlink, D N; Kielstein, J T

    2014-01-01

    and an APAP concentration over 900 mg/L (5960 mmol/L) if NAC is administered (1D). Intermittent hemodialysis (HD) is the preferred ECTR modality in APAP poisoning (1D). CONCLUSION: APAP is amenable to extracorporeal removal. Due to the efficacy of NAC, ECTR is reserved for rare situations when the efficacy...... of NAC has not been definitively demonstrated....

  14. Extracorporeal Treatment for Salicylate Poisoning

    DEFF Research Database (Denmark)

    Juurlink, David N; Gosselin, Sophie; Kielstein, Jan T

    2015-01-01

    that salicylates are dialyzable by hemodialysis and hemoperfusion (level of evidence=B) and recommended extracorporeal treatment in patients with severe salicylate poisoning (1D), including any patient with altered mental status (1D), with acute respiratory distress syndrome requiring supplemental oxygen (1D...

  15. Acute arsenic poisoning diagnosed late.

    Science.gov (United States)

    Shumy, Farzana; Anam, Ahmad Mursel; Kamruzzaman, A K M; Amin, Md Robed; Chowdhury, M A Jalil

    2016-04-01

    Acute arsenicosis, although having a 'historical' background, is not common in our times. This report describes a case of acute arsenic poisoning, missed initially due to its gastroenteritis-like presentation, but suspected and confirmed much later, when the patient sought medical help for delayed complications after about 2 months.

  16. Amnesic shellfish poisoning: A review

    NARCIS (Netherlands)

    Apeldoorn ME van; Egmond HP van; Speijers GJA; CSR; ARO; CSR

    1999-01-01

    Deze literatuurstudie bevat informatie betreffende het 'amnesic shellfish poisoning' (ASP) syndroom en de veroorzakende ASP toxines, van welke "domoic acid" de belangrijkste component is. Chemische structuren en detectie-methodes van ASP toxines, de bronnen voor ASP toxines,

  17. Lead poisoning by contaminated flour.

    Science.gov (United States)

    Hershko, C; Eisenberg, A; Avni, A; Grauer, F; Acker, C; Hamdallah, M; Shahin, S; Moreb, J; Richter, E; Weissenberg, E

    1989-01-01

    Between October 1982 and June 1983, 43 patients were identified with symptomatic lead poisoning in three Arab villages of the Nablus district. Because of the clustering of clinical poisoning by household units, investigation was focussed on potential sources common to all members of the households. After excluding water, olive oil and a variety of foodstuff, lead in high concentrations was discovered in locally ground flour in all affected households. The source of poisoning was lead poured into the fissures between the metal housing and the driveshaft of the millstone. Significant lead contamination of freshly ground flour was demonstrated in 23% of the 146 community flour mills operating in West Bank villages. Since the completion of these studies, similar outbreaks of lead poisoning caused by contaminated flourmills have been identified in the Upper Galilee and in Spain. As the methods of milling in the Mediterranean area are similar, a coordinated international effort is needed in order to eliminate this health hazard from countries where similar community stone mills are still in use.

  18. Paralytic shellfish poisoning; A review

    NARCIS (Netherlands)

    Mons MP; Egmond HP van; Speijers GJA; CSR

    1998-01-01

    Paralytic shellfish poisoning (PSP) wordt veroorzaakt door consumptie van schelpdieren die PSP toxinen bevatten. Er zijn 18 verschillende PSP toxinen, waarvan saxitoxine de meest bekende en de meest toxische is. PSP toxinen kunnen worden aangetoond met de muis bioassay, waarbij de dood van het d

  19. Paralytic shellfish poisoning; A review

    NARCIS (Netherlands)

    Mons MP; Egmond HP van; Speijers GJA; CSR

    1998-01-01

    Paralytic shellfish poisoning (PSP) is caused by ingestion of shellfish containing PSP toxins. The PSP toxins are a group of 18 closely related tetrahydropurines. The first PSP toxin chemically characterised was saxitoxin. The various PSP toxins significantly differ in toxicity, with saxitoxin being

  20. Ciguatera fish poisoning: a review

    NARCIS (Netherlands)

    Fouw JC de; Egmond HP van; Speijers GJA; CSR

    2001-01-01

    This review on ciguatera fish poisoning contains information on the ciguatera intoxication syndrome and the provoking ciguatoxins (CTXs) and gambiertoxin-4b (GTX-4B), of which CTX-1 is a major component at the end of food chain (the carnivore fish). Data on chemical structures and detection methods

  1. [Poisonous animals registration in Poland].

    Science.gov (United States)

    Mitrus, Małgorzata; Szkolnicka, Beata; Satora, Leszek; Morawska, Jowanka

    2005-01-01

    The Act on Nature Conservation of 16.04.2004 (Official Journal, 2004, No 92, item 880) imposes on private individuals the duty to register some animals. The data collected by Kraków municipal authorities and delivered to the Poison Information Centre (Colleglum Medicum, Jagiellonian University) indicate that there are following species in private hands in the city and its surroundings: 11 individuals of Naja naja, 2--Hydrodynates gigas and 55-- Dendrobates spp. According to these information the employees of the PIC elaborated the advice on the treatment of specific animals' poisoning. In the period May 2003 - May 2004 (before the above Act came into force) there were 143 individuals from Brachypelma genus and 3 scorpions (Pandinus imperator) registered in Krakow. These species produce venoms which take local effect. According to art. 64 (1) of the above Act it is compulsory to register amphibians, reptiles, birds and mammals. However, it would be desirable to introduce the duty to register also dangerous species of invertebrates and fishes. It would provide the complete list of poisonous animals kept in private hands. Thus, it would be possible to estimate any possible threats and to elaborate adequate treatment in case of specific animals' poisoning.

  2. Amitraz: a mimicker of organophosphate poisoning.

    Science.gov (United States)

    Dhooria, Sahajal; Behera, Digambar; Agarwal, Ritesh

    2015-10-01

    Amitraz is used as an ectoparasiticide for dogs and cattle. Human poisoning due to amitraz may be misdiagnosed as organophosphate/carbamate (OPC) toxicity, since amitraz poisoning shares several clinical features (miosis, bradycardia and hypotension) encountered with OPC poisoning. A 19-year-old man with an alleged history of suicidal ingestion of a pesticide presented with drowsiness and was found to have constricted pupils, hypotension and bradycardia. He was diagnosed as a case of OPC poisoning and was treated with atropine and pralidoxime prior to presentation to our centre. Absence of a hypersecretory state, and the presence of hyperglycaemia and hypothermia along with a normal serum cholinesterase level suggested an alternate possibility. Retrieval of the poison container confirmed the diagnosis of amitraz poisoning. The patient made a rapid recovery with supportive management. Clinician awareness is key to successful management of this poisoning, which carries a good prognosis.

  3. Central respiratory failure during acute organophosphate poisoning.

    Science.gov (United States)

    Carey, Jennifer L; Dunn, Courtney; Gaspari, Romolo J

    2013-11-01

    Organophosphate (OP) pesticide poisoning is a global health problem with over 250,000 deaths per year. OPs affect neuronal signaling through acetylcholine (Ach) neurotransmission via inhibition of acetylcholinesterase (AChE), leading to accumulation of Ach at the synaptic cleft and excessive stimulation at post-synaptic receptors. Mortality due to OP agents is attributed to respiratory dysfunction, including central apnea. Cholinergic circuits are integral to many aspects of the central control of respiration, however it is unclear which mechanisms predominate during acute OP intoxication. A more complete understanding of the cholinergic aspects of both respiratory control as well as neural modification of pulmonary function is needed to better understand OP-induced respiratory dysfunction. In this article, we review the physiologic mechanisms of acute OP exposure in the context of the known cholinergic contributions to the central control of respiration. We also discuss the potential central cholinergic contributions to the known peripheral physiologic effects of OP intoxication.

  4. New recognition on control concept of mercury hazards and diagnostic criteria of mercury poisoning%对汞危害防治理念与汞中毒诊断标准的新认知

    Institute of Scientific and Technical Information of China (English)

    郝克文; 郭友东; 黄蓉; 余素娥; 金环荣

    2012-01-01

    Mercury is a heavy metal toxic substance of occupation hazard factor, which has irritation, immune pathogenicity, renal toxicity, neurotoxicity and oral toxicity, it may cause serious harm to health and safety of workers, and the serious should induce poisoning. The control and prevention of mercury hazards has always been the major task of occupational health and occupational medicine in China, and mercury hazards is one of occupational diseases that government make a law to ensure the health and safety of workers. Based on the national conditions, there are only prevention regulations and diagnostic criteria according to occupational mercury hazards in the foretime, and is lack of prevention and diagnosis of non-occupational mercury hazards. Therefore, the authors review the new recognition of non-occupational hazards of mercury and diagnosis of non-occupational mercury poisoning by literature review and working practice.%汞作为职业病危害因素的一种重金属高毒物质,因其具有刺激性、免疫致病性、肾脏毒性、神经毒性、口腔毒性等,对劳动者的健康与安全危害较强,严重者可致中毒.对于汞危害的防治,历来是国家职业卫生与职业医学的主要任务,也是党和政府为保护广大劳动者健康与安全,立法开展的职业病防治工作之一.立于国情,先前只从职业性汞危害的角度制定了防治法规和诊断标准,对非职业性汞危害防治、诊断的问题有所疏漏.为此,作者从非职业性汞危害与非职业性汞中毒诊断的层面,通过文献复习及工作实践获得的一些新认知做一综述.

  5. Metal Poisoning: Threat and Management

    Directory of Open Access Journals (Sweden)

    SJS Flora

    2009-12-01

    Full Text Available Exposure to toxic metals remains a wide spread occupational and environmental problems in world. Due to their widespread use in human activities such as industry, agriculture and even as medicine numerous health risks may be associated with exposure to these substances. Lead, arsenic and cadmium generally interferes with a number of body functions such as the haematopoietic system, central nervous system (CNS, liver and kidneys. Over the past few decades there have been growing awareness and concern that the toxic biochemical and functional effects are occurring at lower level of metal exposure than those that produce overt clinical and pathological signs and symptoms. Despite many years of research we are still far from an effective treatment of chronic heavy metal poisoning. The main therapeutic option for chronic metal poisoning relies in chelation therapy. Chelating agents are capable of linking together metal ions to form complex structures which can be easily excreted from the body. They have been used clinically as antidotes for acute and chronic poisoning. 2, 3-dimercaprol (BAL has long been the mainstay of chelation therapy of lead or arsenic poisoning. Meso 2, 3, -dimercaptosuccinic acid (DMSA has been tried successfully in animals as well as in few cases of human lead or arsenic poisoning. However, one of the major disadvantages of chelation with DMSA has been its inability to remove heavy metal from the intracellular sites because of its lipophobic nature. Further, it does not provide protection in terms of clinical/ biochemical recovery. A new trend in chelation therapy has emerged to use combined treatment. This includes use of structurally different chelating agents or a combination of an antioxidant and a chelator to provide better clinical/biochemical recovery in addition to mobilization of heavy metal form intracellular sites. The present review article attempts to provide update information about the current strategies being

  6. Discussing epigenetics in Southern California: a report from the International Symposium on Epigenetic Control and Cellular Plasticity, UCI, December 15-16, 2011.

    Science.gov (United States)

    Rattner, Barbara P

    2012-04-01

    With the goal of discussing how epigenetic control and chromatin remodeling contribute to the various processes that lead to cellular plasticity and disease, this symposium marks the collaboration between the Institut National de la Santé et de la Recherche Médicale (INSERM) in France and the University of California, Irvine (UCI). Organized by Paolo Sassone-Corsi (UCI) and held at the Beckman Center of the National Academy of Sciences at the UCI campus December 15-16, 2011, this was the first of a series of international conferences on epigenetics dedicated to the scientific community in Southern California. The meeting also served as the official kick off for the newly formed Center for Epigenetics and Metabolism at the School of Medicine, UCI (http://cem.igb.uci.edu).

  7. Studies on potential biological control agents of immature mosquitoes in sewage wastewater in southern California.

    Science.gov (United States)

    Mian, L S; Mulla, M S; Wilson, B A

    1986-09-01

    Three biological control agents, a copepod, Mesocyclops leuckarti pilosa, and two fish, Cyprinodon macularius and Poecilia reticulata, were evaluated for their survival in secondary sewage effluent (SSE) and predation potential on mosquito larvae. Results showed that the survival of M. l. pilosa was not significantly affected in SSE or SSE diluted (50%) with water. In predation tests, the copepod consumed from 50 to 90% of the 1st-instar larvae of Culex quinquefasciatus in 24 to 72 hr and P. reticulata fed on almost all stages (egg to pupa) of the test mosquitoes. Survivorship of P. reticulata and C. macularius in SSE was not significantly affected by SSE under both greenhouse and sewage aquaculture conditions. Poecilia reticulata was distributed towards the influent end and C. macularius towards the effluent end of the aquaculture ponds, indicating the former species can tolerate higher levels of pollution which exists at the influent end of the pond. However, low water temperature and dissolved oxygen may be detrimental to these fish species in sewage aquacultural systems.

  8. ORIGINAL ARTICLE: Acute Poisoning with Organophosphorus Pesticide: Patients Admitted to A Hospital in Bijapur, Karnataka.

    Directory of Open Access Journals (Sweden)

    Indira A. Hundekari

    2012-01-01

    Full Text Available Background: Organophosphorus compounds are the pesticides most often involved in human poisoning. Toxicity of these compounds is due to the inhibition of acetyl cholinesterase at cholinergic junctions of the nervous system. Aims & Objectives: Toxicities of OP pesticidescause adverse effects on many organs and systems hence the present study was planned to study the plasma Cholinesterase, serumcholesterol and thyroid function tests in acute organophosphorus pesticide poisoning. Materials and Methods: Plasma ChE, serumcholesterol and serum triiodothyronine, thyroxine, and thyroid stimulating hormone levels were estimated using standard methods.Result: In our study we found the maximum (95% cases were suicidal poisoning. We found that the incidence of poisoning was more common among age group between 15-35 years and males (57% were more likely to attempt suicide as compared to females (38%. Among the organophosphorus compounds the most commonly used were dimethoate,monocrotophos, chlorpyriphos. 79% organophosphorus poisoned patients recovered, while 21% died. Plasma Cholinesterase levels were significantly (p<0.001 decreased in all grades of organophosphate poisoning as compared to controls. Inhibition of Plasma Cholinesterase occurs at the time of admission due to toxic effect of organophosphorus compounds; but the levels significantly (p<0.001 normalized after treatment i.e. on the last day of hospitalization. Serum total cholesterol levels significantly decreased (p<0.001 in all grades of organophosphate poisoning cases as compared to controls without any change after treatment as compared with the patients before treatment. There was a slight and nonsignificant decrease in serum triiodothyronine and serum thyroxine levels in organophosphorus poisoning cases without anysignificant change in serum thyroid stimulating hormone levels as compared to control. The organophosphorus poisoned patients after treatment do not show more changes in their

  9. Inconsistent food safety pressures complicate environmental conservation for California produce growers

    Directory of Open Access Journals (Sweden)

    Patrick Baur

    2016-08-01

    Full Text Available Controlling human pathogens on fresh vegetables, fruits and nuts is imperative for California growers. A range of rules and guidelines have been developed since 2006, when a widespread outbreak of E. coli O157:H7 was linked to bagged spinach grown in California. Growers face pressure from industry and government sources to adopt specific control measures on their farms, resulting in a complex, shifting set of demands, some of which conflict with environmental stewardship. We surveyed 588 California produce growers about on-farm practices related to food safety and conservation. Nearly all respondents considered both food safety and environmental protection to be important responsibilities for their farms. Responses indicate that clearing vegetation to create buffers around cropped fields, removing vegetation from ditches and ponds, and using poison bait and wildlife fences are commonly used practices intended to reduce wildlife movements onto farm fields. The survey also revealed that on-farm practices vary substantially even among farms with similar characteristics. This variability suggests inconsistencies in food safety requirements, auditors' interpretations or growers' perception of the demands of their buyers. Although site-specific considerations are important and practices should be tailored to local conditions, our findings suggest growers, natural resources and food safety would benefit from clearer, more consistent requirements.

  10. Mineral Controls on Microbial Niche Space in Subsurface Serpentinites of the Coast Range Ophiolite, Northern California

    Science.gov (United States)

    Cardace, D.; Carnevale, D.; Schrenk, M. O.; Twing, K. I.; McCollom, T. M.; Hoehler, T. M.

    2012-12-01

    Serpentinites on Earth are excellent candidate environments for the origin of life and continue to serve as an outstanding model system for study of modern selection pressures (such as gradients in temperature, pressure, aqueous geochemistry, oxidation-reduction potential) on microbial communities. Recent coring (August 2011) in the Coast Range Ophiolite near Lower Lake, CA resulted in the establishment of two sets of reference continental serpentinite cores (to 30 and 42 m depth, respectively) and the installation of eight monitoring wells drawing from different depths. Six of these wells plumb serpentinizing waters, with characteristic high pH (up to 12.5), high calcium loads (10-200 ppm), and methane concentrations that are at or near one-atmosphere saturation, while hydrogen levels are orders of magnitude lower than is typically observed in other similar systems. Low hydrogen levels are cryptic; they may reflect consumption by microbial communities or possibly a pressure- or temperature-related solubility response. Two reference wells provide access to quasi-parallel, shallower groundwater flow regimes with near neutral pH values and surface-related major element and organic acid inventories. Many environmental parameters pertinent to microbiological communities active in serpentinites (such as dissolved hydrogen, methane, and other gas concentrations, redox status, ambient pH, and ionic strength) are largely controlled by host rock mineralogy and, thus, the temperature and progress of serpentinization. Since iron partitioning between co-existing minerals in serpentinites is strongly linked to the evolution of hydrogen (McCollom and Bach, 2009), we report here on mineralogy, bulk geochemistry, and selected mineral chemistry data for the serpentinite cores in order to constrain the production of hydrogen, the dominant bioenergetic driving force in this land-based deep biosphere setting. Parallel microbiological analyses of the same drill cores have shown the

  11. Recovery Act: Federspiel Controls (now Vigilent) and State of California Department of General Services Data Center Energy Efficient Cooling Control Demonstration. Final technical project report

    Energy Technology Data Exchange (ETDEWEB)

    Federspiel, Clifford; Evers, Myah

    2011-09-30

    Eight State of California data centers were equipped with an intelligent energy management system to evaluate the effectiveness, energy savings, dollar savings and benefits that arise when powerful artificial intelligence-based technology measures, monitors and actively controls cooling operations. Control software, wireless sensors and mesh networks were used at all sites. Most sites used variable frequency drives as well. The system dynamically adjusts temperature and airflow on the fly by analyzing real-time demands, thermal behavior and historical data collected on site. Taking into account the chaotic interrelationships of hundreds to thousands of variables in a data center, the system optimizes the temperature distribution across a facility while also intelligently balancing loads, outputs, and airflow. The overall project will provide a reduction in energy consumption of more than 2.3 million kWh each year, which translates to $240,000 saved and a reduction of 1.58 million pounds of carbon emissions. Across all sites, the cooling energy consumption was reduced by 41%. The average reduction in energy savings across all the sites that use VFDs is higher at 58%. Before this case study, all eight data centers ran the cooling fans at 100% capacity all of the time. Because of the new technology, cooling fans run at the optimum fan speed maintaining stable air equilibrium while also expending the least amount of electricity. With lower fan speeds, the life of the capital investment made on cooling equipment improves, and the cooling capacity of the data center increases. This case study depicts a rare technological feat: The same process and technology worked cost effectively in eight very different environments. The results show that savings were achieved in centers with diverse specifications for the sizes, ages and types of cooling equipment. The percentage of cooling energy reduction ranged from 19% to 78% while keeping temperatures substantially within the

  12. 76 FR 38155 - California State Nonroad Engine Pollution Control Standards; Ocean-Going Vessels At-Berth in...

    Science.gov (United States)

    2011-06-29

    ... Regulation is designed to reduce emissions of oxides of nitrogen and particulate matter from auxiliary diesel... restricted by statute. EPA's Office of Transportation and Air Quality also maintains a webpage that contains... California ports (``At-Berth Regulation'').\\1\\ The At-Berth Regulation is designed to significantly...

  13. Extracorporeal treatment for carbamazepine poisoning

    DEFF Research Database (Denmark)

    Ghannoum, Marc; Yates, Christopher; Galvao, Tais F

    2014-01-01

    CONTEXT: The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup was created to provide evidence and consensus-based recommendations on the use of extracorporeal treatments (ECTRs) in poisoning. OBJECTIVES: To perform a systematic review and provide clinical recommendations for ECTR...... Method to quantify disagreement. Anonymous votes were compiled, returned, and discussed in person. A second vote determined the final recommendations. RESULTS: Seventy-four articles met inclusion criteria. Articles included case reports, case series, descriptive cohorts, pharmacokinetic studies, and in......-vitro studies; two poor-quality observational studies were identified, yielding a very low quality of evidence for all recommendations. Data on 173 patients, including 6 fatalities, were reviewed. The workgroup concluded that carbamazepine is moderately dialyzable and made the following recommendations: ECTR...

  14. The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis.

    Directory of Open Access Journals (Sweden)

    Felix A Achana

    Full Text Available There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compared any intervention against a "usual care or no intervention" which potentially limits the usefulness of the analysis to decision makers. We aim to use network meta-analysis to simultaneously evaluate the effectiveness of different interventions to increase prevalence of safe storage of i Medicines only, ii Other household products only, iii Poisons (both medicines and non-medicines, iv Poisonous plants; and v Possession of poison control centre (PCC telephone number in households with children.Data on the effectiveness of poison prevention interventions was extracted from primary studies identified in 2 newly-undertaken systematic reviews. Effect estimates were pooled across studies using a random effects network meta-analysis model.28 of the 47 primary studies identified were included in the analysis. Compared to usual care intervention, the intervention with education and low cost/free equipment elements was most effective in promoting safe storage of medicines (odds ratio 2.51, 95% credible interval 1.01 to 6.00 while interventions with education, low cost/free equipment, home safety inspection and fitting components were most effective in promoting safe storage of other household products (2.52, 1.12 to 7.13, safe storage of poisons (11.10, 1.60 to 141.50 and possession of PCC number (38.82, 2.19 to 687.10. No one intervention package was more effective than the others in promoting safe storage of poisonous plants.The most effective interventions varied by poison prevention practice, but education alone was not the most effective intervention for any poison prevention practice. Commissioners and providers of poison prevention interventions should tailor the interventions they commission or provide to the

  15. Alsike clover poisoning: A review

    OpenAIRE

    Nation, P. Nicholas

    1989-01-01

    Trifolium hybridum (alsike clover) has been implicated as the cause of two diseases of the horse. One of these is photosensitivity, of which alsike clover is only one of a number of presumed causal agents. The other is a fatal syndrome which is known as “alsike clover poisoning” and which is manifest by progressive loss of condition, signs of hepatic failure, and varying degrees of neurological impairment. The underlying lesion of alsike clover poisoning is fibrosis and proliferation of the b...

  16. Dermoscopy of black-spot poison ivy.

    Science.gov (United States)

    Rader, Ryan K; Mu, Ruipu; Shi, Honglan; Stoecker, William V; Hinton, Kristen A

    2012-10-15

    Black-spot poison ivy is an uncommon presentation of poison ivy (Toxicodendron) allergic contact dermatitis. A 78-year-old sought evaluation of a black spot present on her right hand amid pruritic vesicles. The presentation of a black spot on the skin in a clinical context suggesting poison ivy is indicative of black-spot poison ivy. Dermoscopy revealed a jagged, centrally homogeneous, dark brown lesion with a red rim. A skin sample was obtained and compared against a poison ivy standard using ultra-fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS). This finding confirmed the presence of multiple urushiol congeners in the skin sample. Black-spot poison ivy may be added to the list of diagnoses that show a specific dermoscopic pattern.

  17. The characteristics of emergency department presentations related to acute herbicide or insecticide poisoning in South Korea between 2011 and 2014.

    Science.gov (United States)

    Moon, Jeong Mi; Chun, Byeong Jo; Cho, Yong Soo

    2016-01-01

    The aim of this study was to examine epidemiologic data regarding acute herbicide or insecticide poisoning in adults from 2011 to 2014 at the national level in South Korea. Further, the association between governmental regulations involving pesticides and changes in pesticide poisoning occurrences over time was determined. Data were obtained from the emergency department (ED)-based Injury In-depth Surveillance system conducted by the Korea Center for Disease Control and Prevention (KCDC). Governmental regulations on pesticides were downloaded from the homepage of the Korea Rural Development Administration. Pesticides were classified according to guidelines provided by the World Health Organization (WHO) and by the respective Resistance Action Committee (RAC). Trends in the number of ED presentations and case fatality rate (CFR) due to pesticide poisoning were investigated. The overall CFR due to poisoning from herbicides or insecticides in adults in South Korea was 16.8% during 2011-2014. However, CFR significantly decreased over the 4-year period. The ED presentations of paraquat (PQ) poisoning fell significantly, whereas poisoning due to glyphosate, glufosinate, or combined herbicides increased markedly over the 4 years. Between 2011 and 2013, PQ was the most common pesticide poisoning, whereas glyphosate became the most frequent in 2014. PQ produced the highest rate of fatality followed by endosulfan. Although the frequency of PQ poisoning decreased, which may be attributed to governmental regulations, the CFR and incidence of pesticide poisoning in adults remain a public health concern that needs to be addressed.

  18. Extracorporeal treatment for tricyclic antidepressant poisoning

    DEFF Research Database (Denmark)

    Yates, Christopher; Galvao, Tais; Sowinski, Kevin M;

    2014-01-01

    The Extracorporeal Treatments In Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatments (ECTR) in poisoning. Here, the workgroup presents its results for tricyclic antidepressants (TCAs). After an extensive literature search, using a predefined...... methodology, the subgroup responsible for this poison reviewed the articles, extracted the data, summarized findings, and proposed structured voting statements following a predetermined format. A two-round modified Delphi method was chosen to reach a consensus on voting statements and RAND...

  19. Hypotension in Severe Dimethoate Self-Poisoning

    OpenAIRE

    Davies, James; Roberts, Darren; Eyer, Peter; Buckley, Nick; Eddleston, Michael

    2008-01-01

    Introduction Acute self-poisoning with the organophosphorus (OP) pesticide dimethoate has a human case fatality three-fold higher than poisoning with chlorpyrifos despite similar animal toxicity. The typical clinical presentation of severe dimethoate poisoning is quite distinct from that of chlorpyrifos and other OP pesticides: many patients present with hypotension that progresses to shock and death within 12–48 h post-ingestion. The pathophysiology of this syndrome is not clear. Case report...

  20. Unilateral Antidotes to DNS Cache Poisoning

    OpenAIRE

    Herzberg, Amir; Shulman, Haya

    2012-01-01

    We investigate defenses against DNS cache poisoning focusing on mechanisms that can be readily deployed unilaterally by the resolving organisation, preferably in a single gateway or a proxy. DNS poisoning is (still) a major threat to Internet security; determined spoofing attackers are often able to circumvent currently deployed antidotes such as port randomisation. The adoption of DNSSEC, which would foil DNS poisoning, remains a long-term challenge. We discuss limitations of the prominent r...

  1. Assessment of Digoxin-Specific Fab Fragment Dosages in Digoxin Poisoning.

    Science.gov (United States)

    Nordt, Sean Patrick; Clark, Richard F; Machado, Carol; Cantrell, F Lee

    2016-01-01

    Digoxin poisoning still remains a common cause of morbidity and mortality. Fortunately, digoxin-specific Fab fragments are commercially available as an antidote. However, these Fab fragments are several thousand dollars per vial. There is a standardized formula to calculate appropriate Fab fragment dosage based on the serum digoxin concentration. This can greatly reduce the amount of Fab fragment administered. There is also an empiric dosing guideline recommending 6-10 vials be given; however, this may result in higher amounts of Fab fragments being administered than required. We performed this study to assess the amounts of digoxin-specific Fab fragments administered in the treatment of digoxin poisonings recorded in a poison control system database from January 1, 2000, to December 31, 2009, in which digoxin serum concentrations were available. This was a retrospective study of 278 patients, 107 with acute poisonings (group A) and 171 following chronic poisoning (group B). In group A, the calculated Fab dose was higher than the calculated dose based on available concentrations in 39 (36%) of group A and 15 (9%) of group B patients. The average wholesale price cost of the excessive dosages ranged from $4818 to as high as $50,589 per patient. Our data suggests that clinician education on digoxin poisoning and the use of the standardized formula to calculate the Fab dose may decrease over utilization and decrease costs associated with the administration of digoxin-specific Fab fragments in the treatment of digoxin poisonings.

  2. Metabolic changes in rat urine after acute paraquat poisoning and discriminated by support vector machine.

    Science.gov (United States)

    Wen, Congcong; Wang, Zhiyi; Zhang, Meiling; Wang, Shuanghu; Geng, Peiwu; Sun, Fa; Chen, Mengchun; Lin, Guanyang; Hu, Lufeng; Ma, Jianshe; Wang, Xianqin

    2016-01-01

    Paraquat is quick-acting and non-selective, killing green plant tissue on contact; it is also toxic to human beings and animals. In this study, we developed a urine metabonomic method by gas chromatography-mass spectrometry to evaluate the effect of acute paraquat poisoning on rats. Pattern recognition analysis, including both partial least squares discriminate analysis and principal component analysis revealed that acute paraquat poisoning induced metabolic perturbations. Compared with the control group, the levels of benzeneacetic acid and hexadecanoic acid of the acute paraquat poisoning group (intragastric administration 36 mg/kg) increased, while the levels of butanedioic acid, pentanedioic acid, altronic acid decreased. Based on these urinary metabolomics data, support vector machine was applied to discriminate the metabolomic change of paraquat groups from the control group, which achieved 100% classification accuracy. In conclusion, metabonomic method combined with support vector machine can be used as a useful diagnostic tool in paraquat-poisoned rats.

  3. POISONOUS PLANTS IN GARDENS AND GRAZING LANDS

    OpenAIRE

    A. AGANGA; M. NSINAMWA; K. OTENG; B. MAULE

    2013-01-01

    This paper is a review of poisonous plants, their toxic agents and the symptoms of poisoning. Poisonous plants are plants, which as a whole or part thereof under all or certain conditions and in amount likely to be taken or into contact with an organism will exert harmful effects or causes death either immediately or by reason of cumulative action of toxic property due to presence of known or unknown chemical action. There are different types of diseases caused by some poisonous plants. Poiso...

  4. Poison ivy dermatitis. Nuances in treatment.

    Science.gov (United States)

    Williford, P M; Sheretz, E F

    1994-02-01

    Acute allergic contact dermatitis due to poison ivy or poison oak is a common presenting complaint in the practices of many primary care physicians. While the clinical features are well described, reported treatment regimens vary in both topical and systemic therapies. We review herein the variability of presenting morphologic features of the disease and common treatment regimens, with attention given to complications of therapy. We also comment on the correct botanical designation, incidence, and immune mechanisms of the disease state and review measures to avoid allergic contact dermatitis due to poison ivy and poison oak.

  5. Organophosphate and carbamate poisoning.

    Science.gov (United States)

    King, Andrew M; Aaron, Cynthia K

    2015-02-01

    Organophosphates (OPs) and carbamates have a wide variety of applications, most commonly as pesticides used to eradicate agricultural pests or control populations of disease-carrying vectors. Some OP and carbamates have therapeutic indications such as physostigmine. Certain organophosphorus compounds, known as nerve agents, have been employed in chemical warfare and terrorism incidents. Both classes inhibit acetylcholinesterase (AChE) enzymes, leading to excess acetylcholine accumulation at nerve terminals. In the setting of toxicity from either agent class, clinical syndromes result from excessive nicotinic and muscarinic neurostimulation. The toxic effects from OPs and carbamates differ with respect to reversibility, subacute, and chronic effects. Decontamination, meticulous supportive care, aggressive antimuscarinic therapy, seizure control, and administration of oximes are cornerstones of management.

  6. Selenium poisoning of fish and wildlife in nature: lessons from twelve real-world examples

    Energy Technology Data Exchange (ETDEWEB)

    Skorupa, J.P. [United States Fish and Wildlife Service, Sacramento, CA (United States)

    1998-09-01

    The chapter presents an inventory of real-world case studies of clearly confirmed or highly probable selenium poisoning in nature. These are of: Belews Lake, North Carolina, Hyco Reservoir in North Carolina, and Martin Reservoir, Texas, all constructed to provide cooling water for large coal-fired power plants; constructed wetland at the Chevron Richmond oil refinery California; Salton Sea, Kesterson Reservoir and Tulane Basin in California, constructed for agricultural drainage; seepage wetlands constructed for the Kenrick Reclamation Project near Casper, Wyoming and at the Ouray National Wildlife Refuse in Utah; an agroforestry demonstration site at Red Rock Ranch, California; Swietzer Lake, Colorado, constructed for recreational purposes and Lake Oltertjarn in Sweden, treated with selenite to mitigate mercury levels in fish. Lessons learned from these studies and the applicability of the US GPA`s freshwater chronic criterion for selenium of 5 {mu}g/L are discussed. 116 refs., 5 figs., 1 tab.

  7. Hospital Performance Indicators and Their Associated Factors in Acute Child Poisoning at a Single Poison Center, Central Saudi Arabia.

    Science.gov (United States)

    Alanazi, Menyfah Q; Al-Jeriasy, Majed I; Al-Assiri, Mohammed H; Afesh, Lara Y; Alhammad, Fahad; Salam, Mahmoud

    2015-12-01

    Admission rate and length of stay (LOS) are two hospital performance indicators that affect the quality of care, patients' satisfaction, bed turnover, and health cost expenditures. The aim of the study was to identify factors associated with higher admission rates and extended average LOS among acutely poisoned children at a single poison center, central Saudi Arabia.This is a cross-sectional, poison and medical chart review between 2009 and 2011. Exposures were child characteristics, that is, gender, age, body mass index (BMI), health history, and Canadian 5-level triage scale. Poison incident characteristics were, that is, type, exposure route, amount, form, home remedy, and arrival time to center. Admission status and LOS were obtained from records. Chronic poisoning, plant allergies, and venomous bites were excluded. Bivariate and regression analyses were applied. Significance at P Poison substances were pharmaceutical drugs (63%) versus chemical products (37%). Main exposure route was oral (98%). Home remedy was observed in (21.9%), which were fluids, solutes, and/or gag-induced vomiting. Almost (52%) arrived to center >1 h. Triage levels: non-urgent cases (58%), less urgent (11%), urgent (18%), emergency (12%), resuscitative (1%). Admission rate was (20.6%) whereas av. LOS was 13 ± 22 h. After adjusting and controlling for confounders, older children (adj.OR = 1.19) and more critical triage levels (adj.OR = 1.35) were significantly associated with higher admission rates compared to younger children and less critical triage levels (adj.P = 0.006) and (adj.P = 0.042) respectively. Home remedy prior arrival was significantly associated with higher av. LOS (Beta = 9.48, t = 2.99), compared to those who directly visited the center, adj.P = 0.003.Hospital administrators are cautioned that acutely poisoned children who received home remedies prior arrival are more likely to endure an extended LOS. This non-conventional practice

  8. Ciguatera Fish Poisoning and Climate Change: Analysis of National Poison Center Data in the United States, 2001–2011

    Science.gov (United States)

    Strickland, Matthew J.; Hess, Jeremy J.

    2014-01-01

    Background: Warm sea surface temperatures (SSTs) are positively related to incidence of ciguatera fish poisoning (CFP). Increased severe storm frequency may create more habitat for ciguatoxic organisms. Although climate change could expand the endemic range of CFP, the relationship between CFP incidence and specific environmental conditions is unknown. Objectives: We estimated associations between monthly CFP incidence in the contiguous United States and SST and storm frequency in the Caribbean basin. Methods: We obtained information on 1,102 CFP-related calls to U.S. poison control centers during 2001–2011 from the National Poison Data System. We performed a time-series analysis using Poisson regression to relate monthly CFP call incidence to SST and tropical storms. We investigated associations across a range of plausible lag structures. Results: Results showed associations between monthly CFP calls and both warmer SSTs and increased tropical storm frequency. The SST variable with the strongest association linked current monthly CFP calls to the peak August SST of the previous year. The lag period with the strongest association for storms was 18 months. If climate change increases SST in the Caribbean 2.5–3.5°C over the coming century as projected, this model implies that CFP incidence in the United States is likely to increase 200–400%. Conclusions: Using CFP calls as a marker of CFP incidence, these results clarify associations between climate variability and CFP incidence and suggest that, all other things equal, climate change could increase the burden of CFP. These findings have implications for disease prediction, surveillance, and public health preparedness for climate change. Citation: Gingold DB, Strickland MJ, Hess JJ. 2014. Ciguatera fish poisoning and climate change: analysis of National Poison Center data in the United States, 2001–2011. Environ Health Perspect 122:580–586; http://dx.doi.org/10.1289/ehp.1307196 PMID:24618280

  9. Validation of a Poison Prevention Program.

    Science.gov (United States)

    Gill, Noel C.; Braden, Barbara T.

    Two way analyses of variance and cross-group descriptive comparisons assessed the effectiveness of the Siop Poison Prevention Program, which included an educational program and the use of warning labels, on improving verbal and visual discrimination of poisonous and nonpoisonous products for preschool children. The study sample consisted of 156…

  10. Poison Awareness: A Discussion Leader's Guide.

    Science.gov (United States)

    National Evaluation Systems, Inc., Amherst, MA.

    Because over 40,000 children are annually poisoned by household products, this guide for group leaders emphasizes hazards and preventive actions. Major objectives are defined: (1) to raise the audience's knowledge/awareness level concerning major hazards associated with potentially poisonous household products, (2) to point out primary hazard…

  11. Upper gastrointestinal hemorrhage caused by superwarfarin poisoning

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Superwarfarins are a class of rodenticides. Gastrointestinal hemorrhage is a fatal complication of superwarfarin poisoning, requiring immediate treatment. Here, we report a 55-year-old woman with tardive upper gastrointestinal hemorrhage caused by superwarfarin poisoning after endoscopic cold mucosal biopsy.

  12. Fatal poisoning among patients with drug addiction

    DEFF Research Database (Denmark)

    Simonsen, K. W.; Christoffersen, D. J.; Banner, J.;

    2015-01-01

    Introduction: Fatal poisonings among drug addicts in Denmark in 2012 were examined. Cause of death, abuse pattern and geographic differences are discussed and data are compared with previous studies. Methods: All fatal poisonings examined at the three institutes of forensic medicine in Denmark in...

  13. Neuropsychiatric manifestations following acute organophosphate poisoning

    Directory of Open Access Journals (Sweden)

    Satyakam Mohapatra

    2016-01-01

    Full Text Available Acute muscarinic and nicotinic side effects of organophosphate (OP poisoning are well known and easily recognized, but neuropsychiatric changes are rarely reported. We are reporting a case of a 22-year-old male who developed psychotic features and motor neuropathy following acute OP poisoning.

  14. Diagnosis & Treatment of Poisoning by Pesticides.

    Science.gov (United States)

    Environmental Protection Agency, Washington, DC. Office of Pesticide Programs.

    This report succinctly discusses the steps necessary to diagnose and treat poisoning from pesticides, especially organophosphates, carbamates and chlorinated hydrocarbons. Immediate and continuing steps in the care of poisoning victims are outlined with supportive information on where to locate emergency assistance. (CS)

  15. Neuromuscular Effects of Acute Organophosphate Poisoning

    Directory of Open Access Journals (Sweden)

    Taylan Pekoz

    2014-08-01

    Conclusion: There is no evoked potential studies performed in organophosphate poisoning althoung electroneurography repetitive and P300 studies exist in literature. More further studies are needed to evaluate the cardiac and neuromuscular effects of organophosphate poisoning. [Cukurova Med J 2014; 39(4.000: 795-800

  16. [Fatal poisoning due to Indigofera].

    Science.gov (United States)

    Labib, S; Berdai, M-A; Bendadi, A; Achour, S; Harandou, M

    2012-01-01

    Indigo, also known in Morocco as Nila, is a dye widely used in the coloring of Moroccan handicrafts. It is obtained from fermentation reactions on the leaves and branches of true indigo, Indigofera tinctoria, which is a widespread plant in tropical Africa and Asia. We report a case of fatal poisoning in a 3-year-old child after administration of indigo for therapeutic purposes. Death resulted from multiple organ failure. The toxicity of this compound is little known in the literature and deserves to be explored through toxicokinetic and toxicodynamic studies, in order to better determine the toxic constituents of the dye.

  17. [Hydrofluoric acid poisoning: case report].

    Science.gov (United States)

    Cortina, Tatiana Judith; Ferrero, Hilario Andrés

    2013-01-01

    Hydrofluoric acid is a highly dangerous substance with industrial and domestically appliances. Clinical manifestations of poisoning depend on exposure mechanism, acid concentration and exposed tissue penetrability. Gastrointestinal tract symptoms do not correlate with injury severity. Patients with history of hydrofluoric acid ingestion should undergo an endoscopy of the upper gastrointestinal tract. Intoxication requires immediate intervention because systemic toxicity can take place. We present a 5 year old girl who accidentally swallowed 5 ml of 20% hydrofluoric acid. We performed gastrointestinal tract endoscopy post ingestion, which revealed erythematous esophagus and stomach with erosive lesions. Two months later, same study was performed and revealed esophagus and stomach normal mucous membrane.

  18. Accidental haloperidol poisoning in children

    Directory of Open Access Journals (Sweden)

    Mona P Gajre

    2012-01-01

    Full Text Available Haloperidol, a butyrophenone neuroleptic drug, is an antipsychotic used in the treatment of adult schizophrenia and mania. It is used in children with neurological disorders like chorea and developmental disorders such as hyperactivity. With the advent of newer selective neuroleptics use of haloperidol is now on decline. However, in adults it is still the preferred drug especially in resource challenged settings. Extrapyramidal reactions occur frequently with haloperidol predominantly as parkinsonian symptoms. There are few case reports of accidental haloperidol poisoning in children and this one of them.

  19. Wetland Plant Physiology Exhibits Controls on Carbon Sequestration Processes in a Restored Temperate Peatland of California, USA

    Science.gov (United States)

    Windham-Myers, L.; Byrd, K. B.; Khanna, S.; Miller, R.; Anderson, F.

    2011-12-01

    Wetland soils, especially peatlands, serve as the leading long-term sink of carbon (C) in the terrestrial biosphere, representing ~5% of global terrestrial ecosystem acreage but ~25% of total stored terrestrial organic C. While inhibition of microbial respiration rates is a necessary component of peat formation, plant processes regulate gross and net organic matter production (GPP and NPP) and microbial respiration in the rhizosphere. Recent work in a 14-year-old, 6-ha experimental wetland complex in the California's Sacramento-San Joaquin Delta has documented that continuous flooding at 25 cm depth can generate peat growth averaging 1 kg C m-2 y-1, and elevation gains approaching 4 cm y-1, 40-fold greater than historic rates tied to mean sea level rise (1mm y-1). To determine macrophyte controls on organic matter production and respiration in emergent marsh habitats, plant physiological processes were examined for 3 dominant species: hardstem bulrush (Schoenoplectus acutus), narrowleaf and broadleaf cattail (Typha angustifolia and T. latifolia). Leaf-level photosynthetic rates (GPP) were collected monthly with a LiCor 6400XT in May-September of 2010 and 2011 across a gradient of water residence time. GPP, stomatal conductance, photosynthetically active radiation (PAR), relative humidity and leaf temperatures were assessed from pre-dawn to solar-noon to assess light-use (LUE) and water-use efficiency (WUE) for carbon assimilation (A). CO2 levels (Ci) were regulated to generate A-Ci curves, indicating leaf capacity to assimilate recycled CO2. Porewater acetate concentrations and live root concentrations of ethanol and acetaldehyde were assayed seasonally in 2011 as relative indices of fermentative respiration. Plant species distribution, NPP and leaf-area indices (LAI) were calculated using allometric relationships, and used to scale-up leaf-level GPP estimates, as well as to ground-truth high-resolution CIR imagery, to compare NDVIs with recent hyperspectral data

  20. Risk factors associated with purchasing pesticide from shops for self-poisoning

    DEFF Research Database (Denmark)

    Weerasinghe, Manjula; Konradsen, Flemming; Eddleston, Michael

    2015-01-01

    -harm. METHODS AND ANALYSIS: This study will investigate risk factors associated with purchasing pesticides for acts of self-poisoning from pesticide shops, including cases identified over a 9-month period using a population-based case-control group approach. Four interviewer-administered data collection tools...... will be used for this study: a semistructured questionnaire, Beck Suicidal Intent Scale (SIS), Clinical Interview Schedule-Sinhalese version (CIS-Sn) and Alcohol Use Disorders Identification Test (AUDIT). Each case (expected n=33) will be compared with two groups of individuals: (1) those who have self......-poisoned using pesticides from the home, home garden or farmland and (2) those who bought pesticides from the same shops as the above cases, but not did not self-poison. Logistic regression models will be used to identify risk factors of purchasing pesticides for self-poisoning from shops. ETHICS...

  1. Treatment of a mild chronic case of ciguatera fish poisoning with intravenous mannitol, a case study.

    Science.gov (United States)

    Mitchell, Gary

    2005-03-01

    This article describes a recent case of ciguatera poisoning treated with intravenous mannitol. Mannitol has been used with good effect in non-controlled studies in acutely severely poisoned patients, but is not described in the treatment of chronic or milder poisoning. Our patient was a 35-year-old Niuean man who had eaten a ciguatoxic fish two weeks previously. His symptoms were not severe but were very unpleasant and restricted his ability to work. He was given a single dose of mannitol (0.66g/kg) as an intravenous infusion over two hours. His symptoms dramatically improved within 24 hours, and within a few days he felt virtually back to his former self. He experienced no side effects to the mannitol. It is suggested that intravenous mannitol may prove to be a useful treatment for mild to moderate ciguatera poisoning, and for patients who present late for treatment.

  2. California's 2002 Clean Water Act Section 303(d) - Impaired Streams and Rivers

    Data.gov (United States)

    California Department of Resources — This dataset contains California's 2002 Clean Water Act Section 303(d) list which is submitted by the California State Water Resources Control Board. The layer has...

  3. SUPERVASMOL POISONING: AN EMERGING ENT EMERGENCY

    Directory of Open Access Journals (Sweden)

    Mitta

    2016-05-01

    Full Text Available Poisoning is one of the commonest modes of suicide in India. Supervasmol poisoning is one of the commonest modes of suicidal attempt in our region. The common cause for consumption of hair dye is by suicidal intent or accidental oral ingestion. There is no specific antidote for Supervasmol poisoning. Management is only symptomatic and supportive with emergency tracheostomy in majority of cases. Hence, we conducted this study to emphasize the role of ENT surgeon in Supervasmol poisoning. STUDY DESIGN Prospective study. MATERIALS AND METHODS We present a total of 79 cases of Supervasmol poisoning who attended the Emergency Department of Narayana Medical College and General Hospital, Nellore. RESULTS All patients were between age group 15-35 yrs. Females are more than males. More patients were in second decade; 55 cases presented in acute phase, 51 patients underwent tracheostomy and four patients were brought dead. CONCLUSION Emergency tracheostomy is a life saving measure in severe stridor

  4. Levothyroxine Poisoning - Symptoms and Clinical Outcome

    DEFF Research Database (Denmark)

    Nygaard, Birgitte; Saedder, Eva A.; Dalhoff, Kim

    2015-01-01

    Levothyroxine (LT), T4, poisoning is rarely associated with a severe outcome. However, cases with significant complications have been reported. The aim of this study was to identify factors associated with symptoms of poisoning including late-onset symptoms. All enquiries to the Danish Poison...... Information Centre (DPIC) concerning LT poisoning between March 2007 and September 2012 were reviewed and the following parameters were recorded: age, dose, time from ingestion, multiple drug intake and symptoms. To evaluate the frequency of late-onset symptoms, a subgroup of patients without initial symptoms...... patients, neither in children nor in adults (age 16-92 years) (p symptoms of poisoning at the time of enquiry; however, in 9 of 21 (43%) patients, we were able to contact, late-onset symptoms existed. In none of the cases...

  5. Environmental controls on spatial patterns in the long-term persistence of giant kelp in central California

    Science.gov (United States)

    Young, Mary Alida; Cavanaugh, Kyle C.; Bell, Tom W.; Raimondi, Peter T.; Edwards, Christopher A.; Drake, Patrick T.; Erikson, Li H.; Storlazzi, Curt

    2016-01-01

    As marine management is moving towards the practice of protecting static areas, it is 44 important to make sure protected areas capture and protect persistent populations. Rocky reefs in 45 many temperate areas worldwide serve as habitat for canopy forming macroalgae and these 46 structure forming species of kelps (order Laminariales) often serve as important habitat for a great 47 diversity of species. Macrocystis pyrifera is the most common canopy forming kelp species found 48 along the coast of California but the distribution and abundance of M. pyrifera varies in space and 49 time. The purpose of this study is to determine what environmental parameters are correlated with 50 the spatial and temporal persistence of M. pyrifera along the central coast of California and how 51 well those environmental parameters can be used to predict areas where M. pyrifera is more likely 52 to persist. Nine environmental variables considered in this study included depth of the seafloor, 53 structure of the rocky reef, proportion of rocky reef, size of kelp patch, biomass of kelp within a 54 patch, distance from the edge of a kelp patch, sea surface temperature, wave orbital velocities, and 55 population connectivity of individual kelp patches. Using a generalized linear mixed effects model 56 (GLMM), the persistence of M. pyrifera was significantly associated with seven of the nine 57 variables considered: depth, complexity of the rocky reef, proportion of rock, patch biomass, 58 distance from the edge of a patch, population connectivity, and wave-orbital velocities. These 59 seven environmental variables were then used to predict the persistence of kelp across the central 60 coast and these predictions were compared to a reserved dataset of M. pyrifera persistence, which 61 was not used in the creation of the GLMM. The environmental variables were shown to accurately 62 predict the persistence of M. pyrifera within the central coast of California (r = 0.71, Pmanagement of these

  6. The epidemiology of childhood poisonings in Cyprus.

    Science.gov (United States)

    Koliou, Maria; Ioannou, Chrystalla; Andreou, Kyriaki; Petridou, Alexandra; Soteriades, Elpidoforos Soterakis

    2010-07-01

    Information on childhood poisonings in Cyprus is limited. Our objective was to examine the epidemiology of poisonings among children in Cyprus. All children up to 15 years of age admitted for poisoning to the Archbishop Makarios Hospital in Nicosia, Cyprus between 2005 and 2008 were included in our study. All hospital poisoning records were reviewed. A total of 257 children were admitted for poisoning. The mean age of children was 3.1 years, of which 83.7% were below the age of 5 years old, while 53% were boys. The poisoning hospitalizations accounted for about 3% of all admissions to the pediatric department during the study period (4 years). The annual cumulative incidence of childhood poisoning hospitalizations was 116 per 100,000 children. Medications accounted for 46.1% of all poisonings, the most frequent cause being paracetamol (9.8%), cardiovascular medications (5.3%), antitussive medications (4.5%), and other painkillers (4.1%). Another 37.6% of hospitalizations involved household products such as household cleaning products (11.8%), petroleum products (11.0%), and rodenticides (5.7%). Among children who ingested petroleum distillates, 55.6% developed clinical symptomatology. The vast majority of cases were accidental (93.8%). Suicidal cases involved children 8-14 years old, mainly girls, and the most frequent poisoning ingested was paracetamol (46.7%). Poisoning hospitalizations represent an important cause of morbidity among children in Cyprus. Preventive strategies should include the education of caregivers on the handling of medications and household products as well as legislation requiring child-resistant packaging for all medications and household products including petroleum distillates.

  7. Arsenic – Poison or medicine?

    Directory of Open Access Journals (Sweden)

    Karolina Kulik-Kupka

    2016-04-01

    Full Text Available Arsenic (As is commonly known as a poison. Only a few people know that As has also been widely used in medicine. In the past years As and its compounds were used as a medicine for the treatment of such diseases as diabetes, psoriasis, syphilis, skin ulcers and joint diseases. Nowadays As is also used especially in the treatment of patients with acute promyelocytic leukemia. The International Agency for Research on Cancer (IARC has recognized arsenic as an element with carcinogenic effect evidenced by epidemiological studies, but as previously mentioned it is also used in the treatment of neoplastic diseases. This underlines the specificity of the arsenic effects. Arsenic occurs widely in the natural environment, for example, it is present in soil and water, which contributes to its migration to food products. Long exposure to this element may lead to liver damages and also to changes in myocardium. Bearing in mind that such serious health problems can occur, monitoring of the As presence in the environmental media plays a very important role. In addition, the occupational risk of As exposure in the workplace should be identified and checked. Also the standards for As presence in food should be established. This paper presents a review of the 2015 publications based on the Medical database like PubMed and Polish Medical Bibliography. It includes the most important information about arsenic in both forms, poison and medicine. Med Pr 2016;67(1:89–96

  8. Chronic lead poisoning in horses

    Energy Technology Data Exchange (ETDEWEB)

    Knight, H.D.; Burau, R.G.

    1973-05-01

    Chronic lead poisoning in horses was manifested as anorexia, loss of body weight, muscular weakness, anemia, laryngeal hemiplegia, and, terminally, inhalation pneumonia. Some deaths were sudden and unexplained. The lead content in liver specimens from 10 horses was greater than that considered indicative of lead intoxication; however, the lead content of blood was equivocal. The most conclusive laboratory finding was increased urine lead concentration after chelation therapy. The concentration of lead in a sample of vegetation considered to be representative of what a horse would eat if he was grazing in the area sampled was 325 ppM (oven-dry basis). It was determined that a 450-kg horse grazing grass of this lead content would consume 2.9 Gm of lead daily (6.4 mg/kg of body weight), an amount considered toxic for horses. Leaching lowered the calcium content of the forage but failed to reduce the lead concentration of the plants significantly, thus opening the possibility that winter rains might have influenced the onset of poisoning. Airborne fallout from a nearby lead smelter was proposed as the primary mode of pasture contamination.

  9. The treatment of acetaminophen poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Prescott, L.F.; Critchley, J.A.

    1983-01-01

    Acetaminophen has become a very popular over-the-counter analgesic in some countries and as a result it is used increasingly as an agent for self-poisoning. Without treatment only a minority of patients develop severe liver damage and 1 to 2% die in hepatic failure. Until Mitchell and his colleagues discovered the biochemical mechanisms of toxicity in 1973 there was no effective treatment. They showed that the metabolic activation of acetaminophen resulted in the formation of a reactive arylating intermediate, and that hepatic reduced glutathione played an essential protective role by preferential conjugation and inactivation of the metabolite. Early treatment with sulphydryl compounds and glutathione precursors has been dramatically effective in preventing liver damage, renal failure, and death following acetaminophen overdosage. It seems likely that these agents act primarily by stimulating glutathione synthesis. Inhibition of the metabolic activation of acetaminophen is another potential therapeutic approach that has not yet been put to the test clinically. The clinical management of acetaminophen poisoning has been transformed and it is particularly gratifying to have effective treatment based on a well established biochemical mechanism of toxicity. It is likely that effective treatment will be developed for toxicity caused through similar mechanisms by other agents.

  10. Basophil degranulation induced by oral poison ivy antigen.

    Science.gov (United States)

    Shelley, W B; Resnik, S S

    1965-08-01

    Seven subjects shown by patch test to be sensitive to poison ivy oleoresin were challenged with graded oral doses of ivy extract. In each instance the circulating basophil leukocytes showed significant degranulation within one hour of challenge. This finding was interpreted as evidence of the presence of immediate-type circulating antibody to ivy antigen in these subjects. No drop in the absolute basophil count was noted, but with higher oral doses the degranulation persisted for several days. Thirteen control subjects showed no change in the basophil morphology or count, indicating that the resin at these levels was not toxic to this cell. All but one of the sensitive subjects showed objective patch test evidence of hyposensitization following the intensive three-week course of oral poison ivy antigen.

  11. Bone changes caused by experimental Solanum malacoxylon poisoning in rabbits

    Directory of Open Access Journals (Sweden)

    José Ignacio Aguirre

    2005-03-01

    Full Text Available The aim of this study was to describe the bone changes observed after a daily oral administration of the calcinogenic plant Solanum malacoxylon (syn. S. glaucophyllum (Sm during 9 days. The Sm-poisoned rabbits had an increase of bone resorption in the endosteal surface of the cortical zone and also in the surface covered by osteoblasts of the primary and secondary spongiosa of the trabecular bone compartment. Moreover, the epiphyseal growth plates in long bones appeared narrower than in the control rabbits, with reduction of the proliferative and hyperthrophic chondrocyte zones. The electron microscopic study revealed a significant decrease of proteoglycans in the hyperthrophic chondrocyte zone evidenced by a significant reduction of rutenium red positive granules in the poisoned rabbit. Altogether, these data suggest that cell differentiation may play a pivotal role in the pathogenesis of Sm-induced bone lesions.

  12. 49 CFR 172.416 - POISON GAS label.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON GAS label. 172.416 Section 172.416... SECURITY PLANS Labeling § 172.416 POISON GAS label. (a) Except for size and color, the POISON GAS label... POISON GAS label and the symbol must be white. The background of the upper diamond must be black and...

  13. 49 CFR 172.540 - POISON GAS placard.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON GAS placard. 172.540 Section 172.540... SECURITY PLANS Placarding § 172.540 POISON GAS placard. (a) Except for size and color, the POISON GAS... the POISON GAS placard and the symbol must be white. The background of the upper diamond must be...

  14. 75 FR 13215 - National Poison Prevention Week, 2010

    Science.gov (United States)

    2010-03-19

    ...#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8484 of March 15, 2010 National Poison... National Poison Prevention Week we alert American families about the dangers of accidental poisonings and... million poison exposures reported each year, we must take every precaution to guard against...

  15. 16 CFR 1700.15 - Poison prevention packaging standards.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Poison prevention packaging standards. 1700.15 Section 1700.15 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS POISON PREVENTION PACKAGING § 1700.15 Poison prevention...

  16. Chronic arsenic poisoning in the north of Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Cebrian, M.E.; Albores, A.; Aguilar, M.; Blakely, E.

    1983-01-01

    We compared the prevalence of signs and symptoms of chronic arsenic poisoning in two rural populations. The arsenic concentration in the drinking water of the exposed population was 0.41 mg/l, and 0.007 mg/l in the control population. The arsenic was present mainly (70%) in its pentavalent form. The objective was to quantitate health effects and risks derived from chronic ingestion of arsenic in contaminated water. In the exposed population, 21.6% of the sample, showed at least one of the cutaneous signs of chronic arsenic poisoning against 2.2% in the control town. Non-specific symptoms were more prevalent in the exposed population and they occurred more frequently in those individuals with skin signs. The relative risk of suffering a particular manifestation of poisoning, ranged from 1.9 to 36 times higher in the exposed population. We estimated the risks above mentioned, which were derived from exposure to minute quantities of arsenic in a known proportion of its oxidation states during a life time period.

  17. Recommended Diagnostic Criteria for Occupational Chronic Lead Poisoning

    Institute of Scientific and Technical Information of China (English)

    SUNJIN-BAI; WANGJIN-PING

    1995-01-01

    The present study aims to recommend the normal upper limit,the acceptable upper limit,the subclinical lead absorption and intoxication diagnostic criteria in an effort to re-evaluate the current national diagnostic criteria for the occupational chronic lead poisoning.The study was conducted on 330 lead exposed workers and 100 non-exposed controls based on the determination of blood and urinary lead,porphyrin metabolism indices,as well as other indices under a nationwide quality control program.The data were subsequently treated by the curve fitting,multi-step transformation to Gauss distribution,and discriminant analysis with the aid of a SAS software package.The relationships between the air lead and blood lead level with certain biological parameters indicative of excessive lead exposure and poisoning were well established.The sensitivity,specificity,accuracy,false positive and false negative results of these critical values were also fully evaluated.This study would be useful for the amendment of the new edition of the national diagnostic criteria for the occupational chronic lead poisoning in China and would provide new approaches for similar investigations.

  18. Confirmed organophosphorus and carbamate pesticide poisonings in South African wildlife (2009–2014

    Directory of Open Access Journals (Sweden)

    Christo J. Botha

    2015-03-01

    Full Text Available During a six-year period (from January 2009 to December 2014, specimens collected from 344 cases of suspected organophosphorus and carbamate pesticide poisonings in wildlife, including birds, were submitted to the Toxicology Laboratory (ARC-OVI for analysis. A positive diagnosis was made in 135 (39% of these cases. The majority of cases were from birds, which included Cape vultures (Gyps coprotheres and African white-backed vultures (Gyps africanus and bateleur eagles (Terathopius ecaudatus. In one incident 49 vultures were killed when a farmer intentionally laced carcasses with carbofuran in an attempt to control jackal predation. There were 22 incidents of poisoning in helmeted guineafowl (Numida meleagris. On nine different occasions blue cranes (Anthropoides paradiseus were poisoned, in one incident 14 birds were reported to have been killed. Over the period of investigation, there were 20 cases of poisoning involving mammalian species, the majority being vervet monkeys (Chlorocebus pygerythrus. The carbamate pesticides were responsible for 57 incidents of poisoning. Aldicarb, carbofuran and methomyl were detected in 26, 18 and 12 cases respectively. The majority of organophosphorus pesticide poisonings were caused by diazinon (n = 19, monocrotophos (n = 13 and methamidophos (n = 10.

  19. Carbon monoxide: an old poison with a new way of poisoning.

    Science.gov (United States)

    Chou, Cheng-Hsiu; Lai, Ching-Huang; Liou, Saou-Hsing; Loh, Ching-Hui

    2012-08-01

    We present two events of carbon monoxide (CO) poisoning, which spread out through ventilation pipes to kill or injure neighbors. This is a previously undocumented poisoning process. In the first event, three people died and eight others suffered CO poisoning from a gas-powered water heater in an apartment building. Similar to the first event, three people expired and three others were injured by CO poisoning in the second event. We subsequently determined the cause of these tragedies were due to obstructions at the openings of ventilation pipes. CO is one of the most common causes of poisoning worldwide and these cases often result in tragedy. Early recognition of CO poisoning resulting from obstructed ventilation pipes will facilitate proper management and prevent possible lethal disasters. Additionally, all clinicians and other paramedical personnel ought to raise the suspicion of chemical-related casualties when encountering clusters of patients from a single locale.

  20. Tropical fish poisoning in temperate climates: food poisoning from ciguatera toxin presenting in Avonmouth.

    Science.gov (United States)

    Kipping, Ruth; Eastcott, Howard; Sarangi, Joyshri

    2006-12-01

    Ciguatera toxin causes a range of gastrointestinal, cardiovascular and neurological symptoms that occur within 1-6 h of ingesting fish with the toxin and can last for days, months or years. It is a well-recognized problem in the tropics. Avon Health Protection Team investigated food poisoning on a ship at Avonmouth, which was thought by the crew to be related to a white snapper fish from the Caribbean. The symptoms were initially thought to be scombroid fish poisoning but were consistent with ciguatera fish poisoning. Cases of fish poisoning from fish imported from the Caribbean and Pacific or travellers returning from tropical countries may be ciguatera fish poisoning, but mistakenly diagnosed as scombroid fish poisoning.

  1. Lead Poisoning in the World and Iran

    Directory of Open Access Journals (Sweden)

    F Azizi

    2010-03-01

    Full Text Available Lead is a relatively ubiquitous heavy metal with particular features such as resistance to corrosion, high malleability and wide variety of industrial applications. In medicine, however, it is considered as a slow-acting toxic substance affecting multiple body systems, specifically functioning as a potent neurotoxin in the central nervous system. Lead poisoning may be acute or chronic and can be due to occupational or environmental exposures. The history of lead poisoning dates back to ancient times. The present paper briefly describes the worldwide historical accounts of lead poisoning with a special focus on Iran.

  2. Chronic mercury poisoning: Report of two siblings.

    Science.gov (United States)

    Yilmaz, Cahide; Okur, Mesut; Geylani, Hadi; Caksen, Hüseyin; Tuncer, Oğuz; Ataş, Bülent

    2010-01-01

    Mercury exists as organic inorganic and elementary forms in nature and is one of the most toxic metals that are poisonous for human beings. Mercury is commonly used in many different sectors of industry such as in insects formulas, agriculture products, lamps, batteries, paper, dyes, electrical/electronic devices, jewelry, and in dentistry. In this study, two siblings (one a 7-year-old boy and the other a 13 years old girl) are reported who developed chronic mercury poisoning as a result of long-term contact with batteries. Our aim is to emphasize the importance of mercury poisoning that is extremely rarely seen in childhood.

  3. Chronic mercury poisoning: Report of two siblings

    Directory of Open Access Journals (Sweden)

    Yilmaz Cahide

    2010-01-01

    Full Text Available Mercury exists as organic inorganic and elementary forms in nature and is one of the most toxic metals that are poisonous for human beings. Mercury is commonly used in many different sectors of industry such as in insects formulas, agriculture products, lamps, batteries, paper, dyes, electrical/electronic devices, jewelry, and in dentistry. In this study, two siblings (one a 7-year-old boy and the other a 13 years old girl are reported who developed chronic mercury poisoning as a result of long-term contact with batteries. Our aim is to emphasize the importance of mercury poisoning that is extremely rarely seen in childhood.

  4. Toxicodendron dermatitis: poison ivy, oak, and sumac.

    Science.gov (United States)

    Gladman, Aaron C

    2006-01-01

    Allergic contact dermatitis caused by the Toxicodendron (formerly Rhus) species-poison ivy, poison oak, and poison sumac-affects millions of North Americans every year. In certain outdoor occupations, for example, agriculture and forestry, as well as among many outdoor enthusiasts, Toxicodendron dermatitis presents a significant hazard. This review considers the epidemiology, identification, immunochemistry, pathophysiology, clinical features, treatment, and prevention of this common dermatologic problem. Recent research in prevention is emphasized, and resources to help in the identification of plants are provided in the bibliography. The literature was searched using a MEDLINE query for "Toxicodendron dermatitis", and the identified article bibliographies were searched as well.

  5. Proposed Closure of Los Angeles Air Force Base, California and Relocation of Space Systems Division

    Science.gov (United States)

    1990-07-01

    californica), black sage ( Salvia mellifera), purple sage ( Salvia leucophylla), deerweed (Lotus scoparius), and poison oak (Toxicodendron diversilobum...Masticophis lateralis var. lateralis), western terrestrial garter snake (Thamnophis elegans var. terrestris) and possibly the western skink (Eumeces...tern Sterna elegans (2)Swainson’s Hawk Buted swainsoni (2) California Yellow-Billed Cuckoo Coccyzus americanus occidentalis (2) U Reptiles Western

  6. Study of the structural control of fluid flow within the Cerro Prieto Geothermal Field, Baja California, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Noble, J.E.; Manon, M.A.; Lippmann, M.J.; Witherspoon, P.A.

    1977-10-01

    The Lawrence Berkeley Laboratory and the Comision Federal de Electricidad of Mexico are conducting a joint investigation of the Cerro Prieto Geothermal Field, located approximately 35 km south of Mexicali, Baja California, Mexico, in the Sea of Cortez-Salton Trough. Recent analyses of various geophysical/electrical logs, temperature logs, production and geochemical data and the subsequently developed preliminary model of the structure of the geothermal system and the distribution of geothermal fluids are presented. Techniques routinely applied to petroleum exploration were successfully used in the development of a preliminary model of this water-dominated system. The study indicates the upwelling of geothermal fluids along an east bounding fault from a deep, as yet unexplored source. The fluids dissipate into various sand horizons at various depths. The resulting stratigraphic and fluid flow model is of importance in planning additional developments of the Cerro Prieto Geothermal Field.

  7. California Political Districts

    Data.gov (United States)

    California Department of Resources — This is a series of district layers pertaining to California'spolitical districts, that are derived from the California State Senateand State Assembly information....

  8. A Gas Chromatography-Mass Spectrometry Based Study on Urine Metabolomics in Rats Chronically Poisoned with Hydrogen Sulfide

    OpenAIRE

    Mingjie Deng; Meiling Zhang; Fa Sun; Jianshe Ma; Lufeng Hu; Xuezhi Yang; Guanyang Lin; Xianqin Wang

    2015-01-01

    Gas chromatography-mass spectrometry (GS-MS) in combination with multivariate statistical analysis was applied to explore the metabolic variability in urine of chronically hydrogen sulfide- (H2S-) poisoned rats relative to control ones. The changes in endogenous metabolites were studied by partial least squares-discriminate analysis (PLS-DA) and independent-samples t-test. The metabolic patterns of H2S-poisoned group are separated from the control, suggesting that the metabolic profiles of H2...

  9. Risk and prognostic factors of inpatient mortality associated with unintentional insecticide and herbicide poisonings: a retrospective cohort study.

    Directory of Open Access Journals (Sweden)

    Wu-Chien Chien

    Full Text Available INTRODUCTION: Pesticide poisoning is an important public health problem worldwide. The study aimed to determine the risk of all-cause and cause-specific inpatient mortality and to identify prognostic factors for inpatient mortality associated with unintentional insecticide and herbicide pesticide poisonings. METHODS: We performed a retrospective cohort study of 3,986 inpatients recruited at hospitalization between 1999 and 2008 in Taiwan. We used the International Classification of Disease, 9th ed., Clinical Modification external causes of injury codes to classify poisoning agents into accidental poisoning by insecticides and herbicides. Comparisons in mortality rates were made between insecticide poisoning patients and herbicide poisoning patients by using the Cox proportional hazards models to estimate multivariable-adjusted hazard ratios (HRs and their 95% confidence intervals (CIs. RESULTS: There were 168 deaths during 21,583 person-days of follow-up evaluation (7.8 per 1,000 person-days. The major causes of mortality for insecticide poisonings were the toxic effect of organophosphate and coma, and the major causes of mortality for herbicide poisonings were the toxic effect of other pesticides and the toxic effect of organophosphate. The mortality for herbicide exposure was fourfold higher than that for insecticide exposure. The factors associated with inpatient mortality were herbicide poisonings (HR = 4.58, 95% CI 3.29 to 6.37 and receiving mechanical ventilation treatment (HR = 3.85, 95% CI 2.73 to 5.42. CONCLUSIONS: We demonstrated that herbicides stand out as the dominant agent for poisoning-related fatalities. The control of and limiting access to herbicide agents and developing appropriate therapeutic regimens, including emergency care, should be priorities.

  10. Pesticide Poisoning of Honeybees: A Review of Symptoms, Incident Classification, and Causes of Poisoning

    Directory of Open Access Journals (Sweden)

    Kiljanek Tomasz

    2016-12-01

    Full Text Available During the 2000s, the problem of pesticide poisoning of honeybees seemed to be almost solved. The number of cases has decreased in comparison to the 1970s. The problem of acute honeybee poisoning, however, has not disappeared, but instead has transformed into a problem of poisoning from ‘traditional’ pesticides like organophosphorus pesticides or pyrethroids, to poisoning from additional sources of ‘modern’ systemic neonicotinoids and fipronil. In this article, the biological activity of pesticides was reviewed. The poisoning symptoms, incident definitions, and monitoring systems, as well as the interpretation of the analytical results, were also reviewed. The range of pesticides, and the detected concentrations of pesticides in poisoned honeybee samples, were reviewed. And, for the first time, cases of poisoning related to neonicotinoids were reviewed. The latter especially is of practical importance and could be helpful to analysts and investigators of honeybee poisoning incidents. It is assumed that secondary poisoning induced by plant collected materials contaminated with systemic pesticides occurs. Food stored in a hive and contaminated with systemic pesticides consumed continuously by the same generation of winter bees, may result in sub-lethal intoxication. This leads to abnormal behaviour identified during acute intoxication. The final result is that the bees discontinue their social role in the honeybee colony super organism, and colony collapse disorder (CCD takes place. The process described above refers primarily to robust and strong colonies that were able to collect plenty of food due to effective plant protection.

  11. GLC analysis of poison ivy and poison oak urushiol components in vegetable oil preparations.

    Science.gov (United States)

    Elsohly, M A; Turner, C E

    1980-05-01

    A procedure is described for the analysis of urushiol content of pharmaceutical preparations containing extracts of poison ivy (Toxicodendron radicans) and poison oak (T. diversilobum) in vegetable oils. The procedure involves extraction of the urushiols from the oily solutions using 90% methanol in water followed by GLC analysis of the extracts. Recoveries of both poison ivy and poison oak urushiols from solutions in corn oil, olive oil, sesame seed oil, and cottonseed oil were calculated. Correlation coefficients (r2) ranged from 0.97 to 1.00, and the coefficients of variations ranged from 3.08 to 7.90%.

  12. Tectonic and eustatic controls of late quaternary shelf sedimentation along the Central California (Santa Cruz) continental margin: high-resolution seismic stratigraphic evidence

    Science.gov (United States)

    Mullins, Henry T.; Nagel, David K.; Dominguez, Laura L.

    1985-07-01

    A high-resolution "uniboom", seismic stratigraphic investigation of a portion of the central California continental shelf has demonstrated that depositional patterns and sequences are controlled largely by an interplay of glacioeustatic sea-level fluctuations superimposed on local tectonics. Wrench tectonics, associated with active right-lateral shear along the San Gregorio fault zone, and the Pigeon Point Basement High control the location, distribution and overall geometry of depositional sequences via en echelon folding and differential subsidence. Areas of relatively thick and thin late Quaternary sediments conform in large part with structures produced during wrenching. Glacioeustatic sea-level oscillations have also shaped depositional patterns and sequences. Correlation of our seismic stratigraphic data with a southern California continental margin sea-level curve, suggests that during the last glacial maximum, approximately 18,000 yrs ago, a relative lowstand resulted in the erosion of a distinct unconformity upon which late Quaternary sediments have accumulated. A rapid rise of sea level to a relative stillstand, approximately 12,000 yrs ago, produced a concave-up, marine terrace profile across the mid-shelf, that has since been infilled with as much as 22 m of Holocene clastic sediments. A relative drop of sea level, approximately 11,000 yrs ago, allowed sediments to build seaward as a series of prograding clinoforms that form the basal sequences of the late Quaternary sediment fill. The succeeding Holocene transgression partially eroded the top of this earlier regressive sequence, and has now established a typical, wave-graded shelf along which sediments fine in a seaward direction to water depths of 90-100 m. At greater shelf water depths, surface sediments coarsen and appear to be relicts of previous relative sea-level lowstands. The presence of now submerged and buried marine terraces along both the central and southern California continental margins

  13. Optimization of Treatment Policy for Acute Carbon Monoxide Poisoning

    Directory of Open Access Journals (Sweden)

    R. N. Akalayev

    2012-01-01

    Full Text Available Objective: to evaluate the efficiency of combination use of hyperbaric oxygenation, succinate-containing solutions, and anti-edematous agents in patients with acute carbon monoxide poisoning. Subjects and methods. The results of treatment were analyzed in 32 patients admitted in 2009—2011 for severe acute carbon monoxide poisoning and a Glasgow coma score of 6—8. The patients were divided into 2 groups: 1 patients whose combination therapy involved hyperbaric oxygenation, Succinasol infusions, and L-lysine-aescinate injections; 2 those who received traditional therapy. All the patients underwent complex clinical, laboratory, and neurophysiologic examinations. Results. Just 24 hours after the combination use of Succinasol and L-lysine-aescinate, Group I patients were observed to have substantially reduced lactate, the content of the latter approached the normal value following 48 hours, which was much below the values in the control group. The similar pattern was observed when endogenous intoxication parameters were examined. During the performed therapy, the level of consciousness and that of intellect according to the MMSE and FAB scales were restored more rapidly in the study group patients than in Group 2. Conclusion. The combination use of hyperbaric oxygenation, the succinate-containing solution Succinasol, and the anti-edematous agent L-lysine-aescinate considerably enhances the efficiency of intensive therapy for acute carbon monoxide poisoning. Key words: carbon monoxide, toxic hypoxic encephalopathy, combination therapy, hyperbaric oxygenation, succinic acid, L-lysine-aescinate.

  14. Red Tide and Paralytic Shellfish Poisoning

    Science.gov (United States)

    Dale, Barrie; Yentsch, Clarice M.

    1978-01-01

    Discusses the nature and cause of paralytic shellfish poisoning (PSP). Includes toxic dinoflagellate ecology, taxonomy and life history, and chemistry of the toxins. Recent work with trace metals and directions of future research are also given. (MA)

  15. Inorganic arsenic poisoning in pastured feeder lambs

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, H.A.; Crane, M.R.; Tomson, K.

    1971-01-01

    Clinical signs and necropsy findings in a group of feeder lambs were suggestive of inorganic arsenic poisoning. Source of exposure was established and toxic concentrations of arsenic were detected in the tissues. 13 references, 1 table.

  16. Amitraz, an underrecognized poison: A systematic review

    Directory of Open Access Journals (Sweden)

    Sahajal Dhooria

    2016-01-01

    Results: The original search yielded 239 articles, of which 52 articles described human cases. After following the inclusion and exclusion criteria, 32 studies describing 310 cases (151 females, 175 children of human poisoning with amitraz were included in this systematic review. The most commonly reported clinical features of amitraz poisoning were altered sensorium, miosis, hyperglycaemia, bradycardia, vomiting, respiratory failure, hypotension and hypothermia. Amitraz poisoning carried a good prognosis with only six reported deaths (case fatality rate, 1.9%. Nearly 20 and 11.9 per cent of the patients required mechanical ventilation and inotropic support, respectively. The role of decontamination methods, namely, gastric lavage and activated charcoal was unclear. Interpretation & conclusions: Our review shows that amitraz is an important agent for accidental or suicidal poisoning in both adults and children. It has a good prognosis with supportive management.

  17. Fatal brodifacoum poisoning in a pony

    OpenAIRE

    Ayala, Ignacio; Rodríguez, Mª Jesús; Martos, Nieves; Zilberschtein, José; Ruíz, Isidro; Motas, Miguel

    2007-01-01

    Fatal brodifacoum poisoning in a pony is described; this condition has not previously been reported in ponies. Discussion of what factors in the pony’s history and treatment may have predisposed to the severity and ultimate death is provided.

  18. Lead poisoning in captive wild animals

    Energy Technology Data Exchange (ETDEWEB)

    Zook, B.C.; Sauer, R.M.; Garner, F.M.

    1972-07-01

    Lead poisoning was diagnosed post-mortem in 34 simian primates, 11 parrots, and 3 Australian fruit bats at the National Zoological Park. Diagnoses were made by the finding of acid-fast intranuclear inclusion bodies in renal epithelia or hepatocytes and, in most cases, by finding excess lead in samples of liver. The estimated prevalence of lead intoxication among autopsied primates and parrots was 44% and 50% respectively. Leaded paint was found in many animal enclosures at this zoo and it was available to all the lead-poisoned animals in this study. The finding of renal intranuclear inclusion bodies in animals at several zoos, scattered reports of lead intoxication of animals dwelling in various zoos, the occurrence of leaded paint in many zoos and the high incidence of lead poisoning at this zoo, indicated that lead poisoning of zoo animals is much more common than was previously thought.

  19. Mercury Poisoning Linked to Skin Products

    Science.gov (United States)

    ... Products For Consumers Home For Consumers Consumer Updates Mercury Poisoning Linked to Skin Products Share Tweet Linkedin ... situations, criminal prosecution. back to top Dangers of Mercury Exposure to mercury can have serious health consequences. ...

  20. Colchicine Poisoning in Children: 7 Case Reports

    Directory of Open Access Journals (Sweden)

    Mehmet Karacan

    2009-09-01

    Full Text Available Colchicine is a drug that has been used primarily in several diseases. Colchicine poisoning is an infrequent but potentially life-threatening problem characterized by multiorgan involvement. We present seven children with colchicine poisoning. Their ages ranged between 1 and 9 years. In six children, the amount of colchicine consumed was between 0.16 and 0.39 mg/kg; the most frequent findings were diarrhea and vomiting. In one patient, the ingested amount was unknown. One of the patients died and all others recovered without sequelae. The severity of colchicine poisoning tends to be related to the dosage of ingested drug and the time of admission to hospital. Symptomatic treatment should be started as soon as possible in colchicine poisoning. (Journal of Current Pediatrics 2009; 7: 96-100

  1. Identification of poisonous plants by DNA barcoding approach.

    Science.gov (United States)

    Bruni, Ilaria; De Mattia, Fabrizio; Galimberti, Andrea; Galasso, Gabriele; Banfi, Enrico; Casiraghi, Maurizio; Labra, Massimo

    2010-11-01

    The plant exposures are one of the most frequent poisonings reported to poison control centres. The diagnosis of intoxicated patients is usually based on the morphological analysis of ingested plant portions; this procedure requires experience in systematic botany, because the plant identification is based on few evident traits. The objective of this research is to test DNA barcoding approach as a new universal tool to identify toxic plants univocally and rapidly. Five DNA barcode regions were evaluated: three cpDNA sequences (trnH-psbA, rpoB and matK) and two nuclear regions (At103 and sqd1). The performance of these markers was evaluated in three plant groups: (1) a large collection of angiosperms containing different toxic substances, (2) congeneric species showing different degrees of toxicity and (3) congeneric edible and poisonous plants. Based on assessments of PCR, sequence quality and resolution power in species discrimination, we recommend the combination of plastidial and nuclear markers to identify toxic plants. Concerning plastidial markers, matK and trnH-psbA showed consistent genetic variability. However, in agreement with CBOL Plant Working Group, we selected matK as the best marker, because trnH-psbA showed some problems in sequences sizes and alignments. As a final and relevant observation, we also propose the combination of matK with a nuclear marker such as At103 to distinguish toxic hybrids form parental species. In conclusion, our data support the claim that DNA barcoding is a powerful tool for poisonous plant identifications.

  2. Causes of rhabdomyolysis in acute poisonings

    Directory of Open Access Journals (Sweden)

    Janković Snežana R.

    2013-01-01

    Full Text Available Background/Aim. Rhabdomyolysis (RM is potentially lethal syndrome, but there are no enough published data on its frequency and characteristics in acute poisonings. The aim of this study was to determine the causes and severity of RM in acute poisonings. Methods. Patients hospital charts were retrospectively screened during a one-year period in order to identify patients with RM among 656 patients treated due to acute poisonings with different agents. All the patients with RM were selected. Entrance criterion was the value of creatine kinase (CK over 250 U/L. The severity of RM was assessed according to the Poison Severity Score. The patients were divided into three groups: the first one with mild RM (CK from 250 to 1,500 U/L, the second with moderate RM (CK from 1,500 to 10,000 U/L and the third with severe RM (CK greater than 10,000 U/L. Results. RM occurred in 125 (19% of the patients with acute poisonings. It was mainly mild (61%, or moderate (36%, and only in 3% of the patients was severe RM. The incidence of RM was the highest in poisonings with opiates (41%, pesticides (38%, neuroleptics (26%, anticonvulsants (26%, ethyl alcohol (20%, and gases (19%. Psychotropic agents were the most common causes of poisoning, and consequently of RM. Fatal outcomes were registered in 32 (25.60% of all RM patients. The incidence of fatal outcomes in poisonings with mild, moderate and severe RM was 19.73%, 31.11% and 75%, respectively. Conclusion. RM syndrome occurs at a relatively high rate in acute poisonings. Although agent’s toxicity is crucial for the outcome, severe RM and its complications may significantly influence the clinical course and prognosis of poisoning. Routine analysis of CK, as a relevant marker for RM may indicate the development of RM in acute poisoning and initiate prompt therapeutic measures in preventing acute renal failure as the most frequent consequence of extensive rhabdomyolysis.

  3. A CLINICAL PROFILE OF ACUTE POISONING

    Directory of Open Access Journals (Sweden)

    Vaddadi

    2015-04-01

    Full Text Available 100 patients were studied to know the common poisons, age, sex, clinical manifestations, response to treatment, motive behind the consumption and prognostic factors. Out of 100 cases, most of them committed this with suicidal intention, 21 - 30 age group, males, insecticide poison consumed were affected. 70% of them had domestic problems as the main reason to commit this extreme step. Those who reached early to the hospital had recovered well with a mortality rate of 7%.

  4. Vital Signs-Alcohol Poisoning Deaths

    Centers for Disease Control (CDC) Podcasts

    2015-01-06

    This podcast is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.  Created: 1/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/6/2015.

  5. Clinical Review: Emergency management of acute poisoning

    Directory of Open Access Journals (Sweden)

    D.J. van Hoving

    2011-06-01

    The aim of this commissioned review was to establish concise guidelines for the initial management of the acutely poisoned patient in the Emergency Centre. The American Academy of Clinical Toxicology and the European Association of Poisons Centres and Clinical Toxicologists are the international leaders in the field of toxicology and the guidelines in their position papers were generally followed. Most of the dosage regimes are according to the South African Medicines Formulary.

  6. Hair dye poisoning and the developing world

    Directory of Open Access Journals (Sweden)

    Sampathkumar Krishnaswamy

    2009-01-01

    Full Text Available Hair dye poisoning has been emerging as one of the important causes of intentional self harm in the developing world. Hair dyes contain paraphenylene-diamine and a host of other chemicals that can cause rhabdomyolysis, laryngeal edema, severe metabolic acidosis and acute renal failure. Intervention at the right time has been shown to improve the outcome. In this article, we review the various manifestations, clinical features and treatment modalities for hair dye poisoning.

  7. Ciguatera poisoning in the Cook Islands.

    Science.gov (United States)

    Bailey, Stephanie; Withers, Tristan

    2014-06-25

    This case report presents two British medical students who contracted ciguatera poisoning while on elective in the Cook Islands. Thirty-six hours after consuming two reef fish they developed paraesthesia of the mouth, hands and feet, myalgia, pruritis and cold allodynia. Neurological examination was normal. Diagnosis of ciguatera poisoning was made on history of reef fish consumption and classical clinical presentation. Management was symptomatic (antihistamines) and both students made a full recovery within 10 weeks.

  8. Ciguatera poisoning in the Cook Islands

    OpenAIRE

    Bailey, Stephanie; Withers, Tristan

    2014-01-01

    This case report presents two British medical students who contracted ciguatera poisoning while on elective in the Cook Islands. Thirty-six hours after consuming two reef fish they developed paraesthesia of the mouth, hands and feet, myalgia, pruritis and cold allodynia. Neurological examination was normal. Diagnosis of ciguatera poisoning was made on history of reef fish consumption and classical clinical presentation. Management was symptomatic (antihistamines) and both students made a full...

  9. Aluminum phosphide poisoning: an unsolved riddle.

    Science.gov (United States)

    Anand, R; Binukumar, B K; Gill, Kiran Dip

    2011-08-01

    Aluminum phosphide (ALP), a widely used insecticide and rodenticide, is also infamous for the mortality and morbidity it causes in ALP-poisoned individuals. The toxicity of metal phosphides is due to phosphine liberated when ingested phosphides come into contact with gut fluids. ALP poisoning is lethal, having a mortality rate in excess of 70%. Circulatory failure and severe hypotension are common features of ALP poisoning and frequent cause of death. Severe poisoning also has the potential to induce multi-organ failure. The exact site or mechanism of its action has not been proved in humans. Rather than targeting a single organ to cause gross damage, ALP seems to work at the cellular level, resulting in widespread damage leading to multiorgan dysfunction (MOD) and death. There has been proof in vitro that phosphine inhibits cytochrome c oxidase. However, it is unlikely that this interaction is the primary cause of its toxicity. Mitochondria could be the possible site of maximum damage in ALP poisoning, resulting in low ATP production followed by metabolic shutdown and MOD; also, owing to impairment in electron flow, there could be free radical generation and damage, again producing MOD. Evidence of reactive oxygen species-induced toxicity owing to ALP has been observed in insects and rats. A similar mechanism could also play a role in humans and contribute to the missing link in the pathogenesis of ALP toxicity. There is no specific antidote for ALP poisoning and supportive measures are all that are currently available.

  10. Toad poisoning in three dogs: case reports

    Directory of Open Access Journals (Sweden)

    CM Barbosa

    2009-01-01

    Full Text Available Toad poisoning is frequent in dogs, but has been infrequently addressed in published case reports and review articles. Dogs can be poisoned when they bite a toad or otherwise ingest the venom. The venom effects manifest soon after the accident, since the toxin is rapidly absorbed by the mucous membrane of the digestive system. Hospital records of three dogs, diagnosed with toad poisoning, were retrospectively reviewed from January 2005 to July 2007. Poisoned dogs may present only local irritation or systemic signs in the gastrointestinal, cardiac and neurological systems. All three cases presented herein had clinical signs of gastrointestinal alterations including vomiting, sialorrhea and diarrhea. Two dogs developed abnormal cardiac rhythm and two exhibited neurological signs. A poisoned animal requires emergency care and symptomatic therapy with intense monitoring of its clinical parameters. Although there have been reports on the low mortality of dogs poisoned by toads, one animal died even after appropriate therapy. The severity of clinical signs and the risk of death must be considered by the veterinarian.

  11. Development of Improved Burnable Poisons for Commercial Nuclear Power Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Renier, J.A.

    2002-04-17

    Burnable poisons are used in all modern nuclear reactors to permit higher loading of fuel without the necessity of an overly large control rod system. This not only permits a longer core life but can also be used to level the power distribution. Commercial nuclear reactors commonly use B{sub 4}C in separate non-fueled rods and more recently, zirconium boride coatings on the fuel pellets or gadolinium oxide mixed with the fuel. Although the advantages are great, there are problems with using these materials. Boron, which is an effective neutron absorber, transmutes to lithium and helium upon absorption of a neutron. Helium is insoluble and is eventually released to the interior of the fuel rod, where it produces an internal pressure. When sufficiently high, this pressure stress could cause separation of the cladding from the fuel, causing overly high centerline temperatures. Gadolinium has several very strongly absorbing isotopes, but not all have large cross sections and result in residual burnable poison reactivity worth at the end of the fuel life. Even if the amount of this residual absorber is small and the penalty in operation small, the cost of this penalty, even if only several days, can be very high. The objective of this investigation was to study the performance of single isotopes in order to reduce the residual negative reactivity left over at the end of the fuel cycle. Since the behavior of burnable poisons can be strongly influenced by their configuration, four forms for the absorbers were studied: homogeneously mixed with the fuel, mixed with only the outer one-third of the fuel pellet, coated on the perimeter of the fuel pellets, and alloyed with the cladding. In addition, the numbers of fuel rods containing burnable poison were chosen as 8, 16, 64, and 104. Other configurations were chosen for a few special cases. An enrichment of 4.5 wt% {sup 235}U was chosen for most cases for study in order to achieve a 4-year fuel cycle. A standard pressurized

  12. Late Neogene stratigraphy and tectonic control on facies evolution in the Laguna Salada Basin, northern Baja California, Mexico

    Science.gov (United States)

    Martín-Barajas, A.; Vázquez-Hernández, S.; Carreño, A. L.; Helenes, J.; Suárez-Vidal, F.; Alvarez-Rosales, J.

    2001-10-01

    The Laguna Salada Basin (LSB) in northeastern Baja California records late-Neogene marine incursions in the Salton Trough and progradation of the Colorado River delta. Early subsidence and subsequent tectonic erosion are related to evolution of the Sierra El Mayor detachment fault during late Miocene time (geothermal exploratory well on the eastern margin of LSB. Interfingering fluvial-sandstone deposits and prograding alluvial fanglomerates with coarse debris-flow and rock-avalanche deposits crudely mark the onset of vertical slip along the Laguna Salada fault and rapid uplift of Sierra Cucapa and Sierra El Mayor. Up to 2 km of Quaternary alluvial-fan and lacustrine deposits accumulated along the eastern margin of LSB, whereas lower subsidence rates produced a thinner sedimentary wedge over a ramp-like crystalline basement along the western margin. In early Pleistocene time (˜2-1 Ma), the Laguna Salada became progressively isolated from the Colorado River delta complex, and the Salton Trough by activity on the Elsinore and Laguna Salada fault zones.

  13. Early Pulomonary Irradiation in Paraquat (Gramoxone) Poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chang Geol; Kim, Gwi Eon; Suh, Chang Ok [Yonsei University College of Medicine, Seoul (Korea, Republic of)

    1995-12-15

    Purpose : To evaluate whether the early pulmonary irradiation can prevent or decrease the pulmonary damage and contribute to improve ultimate survival in paraquat lung. Materials and Methods : From Jun. 1987 to Aug. 1993, thirty patients with paraquat poisoning were evaluated. Fourteen of these patients were received pulmonary irradiation(RT). All of the patients ere managed with aggressive supportive treatment such as gastric lavage, forced diuresis, antioxidant agents and antifibrosis agents. Ingested amounts of paraquat were estimated into three groups(A: minimal < about 5cc, B: mouthful 5-50 cc, C: Large > 50cc). Pulmonary irradiation was started within 24 hours after admission(from day 1 to day 11 after ingestion of paraquat). Both whole lungs were irradiated with AP/PA parallel opposing fields using C0-60 teletherapy machine. A total of 10Gy(2Gy/fr. X 5 days)was delivered without correction of lung density. Results : In group A, all patients were alive regardless of pulmonary irradiation and in group C, all of the patients were died due o multi-organ failure, especially pulmonary fibrosis regardless of pulmonary irradiation. However, in group B, six of 7 patients(86%) with no RT were died due to respiratory failure, but 4 of 8 patients with RT were alive and 4 of 5 patients who received pulmonary irradiation within 4 days after ingestion of paraquat were all alive though radiological pulmonary fibrosis. All 3 patients who were received pulmonary irradiation after 4 days after ingestion were died due to pulmonary fibrosis in spite of recovery from renal and hepatic toxicity. Conclusion : It is difficult to find out the effect of pulmonary irradiation on the course of the paraquat lung because the precise plasma and urine paraquat concentration were not available between control and irradiation groups. But early pulmonary irradiation within 4 days after paraquat poisoning with aggressive supportive treatment appears to decrease pulmonary toxicity and contribute

  14. Prevalent Poisonings in Adolescents and Adults in Dubai: A Compendium from Rashid Hospital

    Directory of Open Access Journals (Sweden)

    Fahad Akhtar Hameed

    2014-09-01

    Full Text Available Background: Profile of acute poisonings varies from country to country depending on the ease of availability of substances and socio-economic condition of people; however, very little information from the United Arab Emirates (UAE have been published, so far. This study was designed to find out the most common causes of overdose and poisoning in patients admitted to the emergency department of Rashid Hospital (RH, Dubai, UAE. Methods: In this retrospective cross sectional study, medical records of poisoned patients admitted to RH from 1st January 2012 to 31st December 2012 were reviewed. Demographic data, types of substances used, intention, length of hospital stay and outcomes were recorded in pre-designed checklists. Results: Overall, 163 patients were studied that among them gender distribution was relatively equal (male: female = 1.04: 1. Mean age of patients was 30.3 ± 11.5 and most patients were in the age group of 20 to 29 years age old (41.7%. Rgarding the type of poisons, the majority of patients were poisoned with pharmaceuticals (55.8% followed by chemical substances (23.3%. In pharmaceutical poisonings, most cases were due to multi-drug ingestion (22.6%, followed by ingestion of paracetamol (14.1% and benzodiazepines (4.3%. Considering the gender distribution, women were significantly more involved with pharmaceutical poisoning (P = 0.046, while venomous envenomation occurred only in men indicating a significant difference (P = 0.004. In chemical poisoning, most cases were due to ingestion of corrosive agents (19%. Suicidal poisoning was significantly more common in women (P < 0.001, while abuse was significantly more common in men (P < 0.001. Length of hospital stay averaged on 8.1 days. Only 3 patients died during the admission (mortality rate: 1.8%. Conclusion: Study on, training for and prevention of poisoning should receive more attention in the UAE. Over-the-counter drugs especially paracetamol should be prescribed in a more

  15. A Brief History of California School Funding

    Science.gov (United States)

    Canfield, Jacquie

    2013-01-01

    In January 2013, the governor proposed a new funding model for California school districts called the Local Control Funding Formula. As the Legislature debates the proposed new funding model for schools, which is expected to start in the 2013-14 fiscal year, the author thought it would be a good time for a history lesson in California school…

  16. A review of the most economically important poisonous plants to the livestock industry on temperate grasslands of China.

    Science.gov (United States)

    Zhao, Mengli; Gao, Xinlei; Wang, Jing; He, Xiaolei; Han, Bing

    2013-01-01

    The majority of the literature on poisonous plant species in China is published in Chinese and not available to the majority of interested researchers and grassland managers in other countries. Therefore, a review of the Chinese literature was conducted to summarize the occurrence of poisonous plant species on temperate grasslands in China. We reviewed the literature to obtain general information on poisonous species but focus on locoweeds (Astragalus and Oxytropis spp.), drunken horse grass [Achnatherum inebrians (Hance) Keng ex Tzvelev] and langdu (Stellera chamaejasme L.) for information on their toxins, distribution and ecology, control methods and alternate uses. Of the almost 1300 poisonous species found on grasslands in China, these species are responsible for an estimated 80% of all livestock losses. This includes loss of performance as well as mortality. The locoweeds are a complex made up of Oxytropis and Astragalus species. The toxic principle in this complex, as well as in drunken horse grass, is the result of an endophyte fungus whereas in langdu it is produced by the plant. All these species are native to the grasslands, which suggest they have been a problem ever since herding began. Over that period of at least several millennia, herders would have learned and adapted to the presence of poisonous species. Strategies were developed and therapies employed to allow the animals to cope before and after poisoning. Nevertheless, grazing management could still be refined that would allow the use of the toxic legumes, while preventing poisonous symptoms, as has been tested elsewhere.

  17. 76 FR 8942 - Poison Prevention Packaging Requirements; Proposed Exemption of Powder Formulations of...

    Science.gov (United States)

    2011-02-16

    ... COMMISSION 16 CFR Part 1700 Poison Prevention Packaging Requirements; Proposed Exemption of Powder... 1. The Poison Prevention Packaging Act of 1970 and Implementing Regulations The Poison Prevention... children, Packaging and containers, Poison prevention, Toxic substances. For the reasons given above,...

  18. Analysis of Nine Cases of Acute Thallium Poisoning

    Institute of Scientific and Technical Information of China (English)

    WANG Qiwei; HUANG Xiaojiang; LIU Liang

    2007-01-01

    In this study nine cases of thallium poisoning in a series of homicidal poisoning were analyzed in order to provide more information concerning thallium poisoning. It was found that the most common clinical feature of thallium poisoning was peripheral neuropathy and paraesthesia was more common than amyasthenia. Understanding of these clinical characteristics of thallium poisoning was helpful to early identification and differential diagnosis. Since the early administration of Prussian Blue, as a specific antidote for thallium poisoning, can substantially improve the prognosis, it is of great importance to establish a correct and early diagnosis.

  19. Respiratory failure induced by acute organophosphate poisoning in rats: effects of vagotomy.

    Science.gov (United States)

    Gaspari, Romolo J; Paydarfar, David

    2009-03-01

    Acute organophosphate (OP) poisoning causes respiratory failure through two mechanisms: central apnea and pulmonary dysfunction. The vagus nerve is involved in both the central control of respiratory rhythm as well as the control of pulmonary vasculature, airways and secretions. We used a rat model of acute OP poisoning with and without a surgical vagotomy to explore the role of the vagus in OP-induced respiratory failure. Dichlorvos (2,2-dichlorovinyl dimethyl phosphate) injection (100mg/kg subcutaneously, 3 x LD50) resulted in progressive hypoventilation and apnea in all animals, irrespective of whether or not the vagi were intact. However, vagotomized animals exhibited a more rapidly progressive decline in ventilation and oxygenation. Artificial mechanical ventilation initiated at onset of apnea resulted in improvement in oxygenation and arterial pressure in poisoned animals with no difference between vagus intact or vagotomized animals. Our observations suggest that vagal mechanisms have a beneficial effect during the poisoning process. We speculate that vagally mediated feedback signals from the lung to the brainstem serve as a modest protective mechanism against central respiratory depressive effects of the poison and that bulbar-generated efferent vagal signals do not cause sufficient pulmonary dysfunction to impair pulmonary gas exchange.

  20. ARE THE SO-CALLED POISONOUS FOOD-COMBINATIONS REALLY POISONOUS?

    Institute of Scientific and Technical Information of China (English)

    Libin T CHENG

    2009-01-01

    @@ The idea that to eat certain two foods simultaneously is to get poisoned has been entertained by柄Chinese people for many years. There are about 184 pairs of the so-called poisonous food-combinations, and 180 of them are mentioned in Chinese Ancient Materia Medica, Ben-Tsao-Gung-Mu (本草纲目) or other books. (1a,2a) This belief was based upon some personal sketch, old-fashioned doctors' notes, stories and other false facts. Although these statements were originated without any experimental ground, yet many of the Chinese, even at present time, still believe them firmly. Whenever any poisoning outbreak occurs accidentally after having taken the so-called poisonous food-combination, they always attribute the cause of the poisoning to the two foods served simultaneously.

  1. XRCC3、XPD 基因多态性与职业性慢性铅中毒易感性关系病例-对照研究%Matched case-control study on relationship between polymorphisms of gene XRCC3, XPD and the susceptibility of occupational chronic lead poisoning

    Institute of Scientific and Technical Information of China (English)

    刘祥铨; 吴小南; 吴京颖; 刘合焜

    2014-01-01

    目的:探讨X射线交错互补修复基因3(XRCC3) Thr241Met和人类着色性干皮病基因D (XPD) Asp312Asn及Lys751Gln与职业性慢性铅中毒的关系。方法选择103名蓄电池厂确诊为职业性慢性铅中毒的男性工人为病例组,按照工种和年龄1∶1匹配选择同厂无诊断为铅中毒的铅作业男性工人为对照组。采集2组人群周围静脉血,采用聚合酶链反应-限制性片段长度多态性技术检测XRCC3 Thr241Met、XPD Asp312Asn和XPD Lys751Gln位点的多态性,采用条件Logistic回归分析分析不同基因型与职业性慢性铅中毒的关系。结果2组人群中XRCC3 Thr241Met、XPD Asp312Asn和XPD Lys751Gln多态位点的基因型分布均符合遗传学Hardy-Weinberg平衡定律( P>0.05)。2组人群XRCC3 Thr241Met 3种基因型总体分布比较,差异有统计学意义( P<0.05)。2 组人群XPD Asp312Asn和XPD Lys751Gln 3种基因型总体分布分别比较,差异均无统计学意义(P>0.05)。 XRCC3 Thr241Met的CT和TT基因型均增加铅中毒易感性[校正比值比分别为2.44和3.37,95%可信区间为(1.17~5.09)和(1.09~11.14)],而XPD Asp312Asn 和 XPD Lys751Gln 不同基因型与铅中毒易感性无关( P >0.05)。结论 XRCC3 Thr241Met的CT或TT基因型与职业性慢性铅中毒相关;而XPD Asp312Asn和XPD Lys751Gln多态性与职业性慢性铅中毒易感性无关。%Objective To explore the relationship between polymorphisms of gene XRCC3 Thr241Met and XPD Asp312Asn, Lys751Gln and occupational chronic lead poisoning .Methods Based on 1∶1 matched case-control study, 103 couple lead-exposed male workers were selected as the case group ( occupational chronic lead poisoning patients ) and the control group ( workers without poisoning manifestations ) from storage battery factories , and their peripheral venous blood was collected .Single nucleotide polymorphisms of XRCC3 Thr241Met, XPD Asp312

  2. Toxicological management of chlorophacinone poisoning.

    Science.gov (United States)

    Lagrange, F; Corniot, A G; Titier, K; Bedry, R; Pehourcq, F

    1999-01-01

    A 33-year-old man was admitted 8 hours after voluntary ingestion of 1875 mg of chlorophacinone (C'Operat 750 mL). The examination revealed excitation and nausea, with a normal prothrombin index (PI). Comprehensive testing for abused and therapeutic drugs in blood confirmed chlorophacinone (maximum plasma level: 27.6 mg/L), an antivitamin K (AVK) rodenticide. In a search for easy toxicological management of chlorophacinone poisoning treated by phytomenadione and a cytochrome P450 inducer (phenobarbital), PI and chlorophacinone plasma levels were monitored concomitantly during 17 days. A simple HPLC procedure for the determination of chlorophacinone in human plasma is reported for that purpose. Under phenobarbital 200 mg/day, chlorophacinone exhibited an apparent elimination half-life (3.27 days) shorter than in previously reported cases. If PI is useful for planning phytomenadione treatment and used for therapeutic monitoring of AVK, the chlorophacinone concentrations follow-up may provide a better estimation of the duration of hospitalisation. Chlorophacinone accumulation in target cells or existence of an unidentified metabolite may explain persistence of the hypocoagulability syndrome at low plasmatic concentrations of chlorophacinone. This case illustrates how toxicological management may facilitate toxicokinetics and therapeutic data acquisition.

  3. Neurological syndromes following organophosphate poisoning.

    Directory of Open Access Journals (Sweden)

    Singh S

    2000-10-01

    Full Text Available Organophosphorous compounds, the anticholinesterases, produce significant morbidity and mortality in India. Although exact estimates are not available, hospital based statistics suggest that nearly half of the admissions to emergency with acute poisoning are due to organophosphates. Following accidental or suicidal exposure, these anticholinesterases lead to three well defined neurological syndromes i.e. initial life threatening acute cholinergic crisis which often requires management in intensive care unit, intermediate syndrome in which cranial nerve palsies, proximal muscle weakness and respiratory muscle weakness are common and patients often require respiratory support and delayed organophosphate induced polyneuropathy. In addition to these three classical neurological syndromes following acute exposure and in some following low dose chronic exposure, several neurobehavioural changes have been observed and these have been termed together as ′chronic organophosphate induced neuropsychiatric disorders′ (COPIND. Organo-phosphate compounds produce significant pesticide related illness in developing countries. There is, thus, a need to determine exact extent of the problem and to develop appropriate strategies to manage these cases with available resources in these countries.

  4. Geomorphic controls on mercury accumulation in soils from a historically mined watershed, Central California Coast Range, USA

    Science.gov (United States)

    Holloway, J.M.; Goldhaber, M.B.; Morrison, J.M.

    2009-01-01

    Historic Hg mining in the Cache Creek watershed in the Central California Coast Range has contributed to the downstream transport of Hg to the San Francisco Bay-Delta. Different aspects of Hg mobilization in soils, including pedogenesis, fluvial redistribution of sediment, volatilization and eolian transport were considered. The greatest soil concentrations (>30 mg Hg kg-1) in Cache Creek are associated with mineralized serpentinite, the host rock for Hg deposits. Upland soils with non-mineralized serpentine and sedimentary parent material also had elevated concentrations (0.9-3.7 mg Hg kg-1) relative to the average concentration in the region and throughout the conterminous United States (0.06 mg kg-1). Erosion of soil and destabilized rock and mobilization of tailings and calcines into surrounding streams have contributed to Hg-rich alluvial soil forming in wetlands and floodplains. The concentration of Hg in floodplain sediment shows sediment dispersion from low-order catchments (5.6-9.6 mg Hg kg-1 in Sulphur Creek; 0.5-61 mg Hg kg-1 in Davis Creek) to Cache Creek (0.1-0.4 mg Hg kg-1). These sediments, deposited onto the floodplain during high-flow storm events, yield elevated Hg concentrations (0.2-55 mg Hg kg-1) in alluvial soils in upland watersheds. Alluvial soils within the Cache Creek watershed accumulate Hg from upstream mining areas, with concentrations between 0.06 and 0.22 mg Hg kg-1 measured in soils ~90 km downstream from Hg mining areas. Alluvial soils have accumulated Hg released through historic mining activities, remobilizing this Hg to streams as the soils erode.

  5. Dispersal limitation does not control high elevational distribution of alien plant species in the southern Sierra Nevada, California

    Science.gov (United States)

    Rundel, Philip W.; Keeley, Jon E.

    2016-01-01

    Patterns of elevational distribution of alien plant species in the southern Sierra Nevada of California were used to test the hypothesis that alien plant species invading high elevations around the world are typically climate generalists capable of growing across a wide elevational range. The Sierra Nevada has been heavily impacted for more than a century and a half, first by heavy grazing up into high elevation meadows, followed by major logging, and finally, by impacts associated with recreational use. The comparative elevational patterns of distribution and growth form were compared for native and alien plant species in the four families (Asteraceae, Brassicaceae, Fabaceae, and Poaceae) that contribute the majority of naturalized aliens in the study area. The distribution of realized climatic niche breadth, as measured by elevational range of occurrence, was virtually identical for alien and native species, with both groups showing a roughly Gaussian distribution peaking with species whose range covers a span of 1500–1999 m. In contrast to alien species, which only rarely occurred at higher elevations, native species showed a distribution of upper elevation limits peaking at 3000–3499 m, an elevation that corresponds to the zone of upper montane and subalpine forests. Consistent with a hypothesis of abiotic limitations, only a few alien species have been ecologically successful invaders at subalpine and alpine elevations above 2500 m. The low diversity of aliens able to become established in these habitats is unlikely due to dispersal limitations, given the long history of heavy grazing pressure at high elevations across this region. Instead, this low diversity is hypothesized to be a function of life history traits and multiple abiotic stresses that include extremes of cold air and soil temperature, heavy snowfall, short growing seasons, and low resource availability. These findings have significant implications for resource managers.

  6. Neurotoxic Syndromes in Marine Poisonings a Review

    Directory of Open Access Journals (Sweden)

    Gholam Hossein Mohebbi

    2014-08-01

    Full Text Available Background: Marine neurotoxins as of Marine biotoxins are natural toxins that produced mainly by dinoflagellates, diatoms and several species of invertebrates and fish. Marine poisoning results from the ingestion of marine animals contain these toxins and causes considerable adverse effects. Materials and methods: This review provides some facts about the structures of marine neurotoxins, their molecular target and pharmacology, analytical methods for their detection and quantitation, diagnosis and laboratory testing, clinical manifestations, as well as prevention and treatment, if were obtainable. Furthermore, we focus on marine poisoning and various associated neurological syndromes like ciguatera, tetrodotoxin poisoning, and paralytic shellfish poisoning, after ingestion of the common marine toxins. Results: A number of neurotoxins that prescribed according to their potency (LD50 are: Maitotoxin, Ciguatoxins and Palytoxin, Tetrodotoxin and Saxitoxin, Brevetoxins, Azaspiracid, Yessotoxin, Cooliatoxin, Domoic acid and Conotoxins, Respectively. The primary target of most marine neurotoxins is voltage gated sodium channels and the resulting block of ion conductance through these channels. Moreover, these compounds interact with voltage-gated potassium and calcium channels and modulate the flux of stated ions into many cell types. As well, the target recognized for palytoxin is the Na+- K+ /ATPase. Conclusion: Results of reviewed studies revealed that, the Ciguatera is the commonest syndrome of marine poisoning, but is rarely lethal. Puffer fish poisoning results from the ingestion of fish containing tetrodotoxin and paralytic shellfish poisoning are less common, but have a higher fatality rate than ciguatera. Despite their high toxicity, no much research has been done on some of the toxins, like maitotoxin. In addition, there have remained unknown the pharmacological effects, mechanism of action and molecular target of some toxins such as

  7. A Statewide Nested Case–Control Study of Preterm Birth and Air Pollution by Source and Composition: California, 2001–2008

    Science.gov (United States)

    Laurent, Olivier; Hu, Jianlin; Li, Lianfa; Kleeman, Michael J.; Bartell, Scott M.; Cockburn, Myles; Escobedo, Loraine; Wu, Jun

    2016-01-01

    Background: Preterm birth (PTB) has been associated with exposure to air pollution, but it is unclear whether effects might vary among air pollution sources and components. Objectives: We studied the relationships between PTB and exposure to different components of air pollution, including gases and particulate matter (PM) by size fraction, chemical composition, and sources. Methods: Fine and ultrafine PM (respectively, PM2.5 and PM0.1) by source and composition were modeled across California over 2000–2008. Measured PM2.5, nitrogen dioxide, and ozone concentrations were spatially interpolated using empirical Bayesian kriging. Primary traffic emissions at fine scale were modeled using CALINE4 and traffic indices. Data on maternal characteristics, pregnancies, and birth outcomes were obtained from birth certificates. Associations between PTB (n = 442,314) and air pollution exposures defined according to the maternal residence at birth were examined using a nested matched case–control approach. Analyses were adjusted for maternal age, race/ethnicity, education and neighborhood income. Results: Adjusted odds ratios for PTB in association with interquartile range (IQR) increases in average exposure during pregnancy were 1.133 (95% CI: 1.118, 1.148) for total PM2.5, 1.096 (95% CI: 1.085, 1.108) for ozone, and 1.079 (95% CI: 1.065, 1.093) for nitrogen dioxide. For primary PM, the strongest associations per IQR by source were estimated for onroad gasoline (9–11% increase), followed by onroad diesel (6–8%) and commercial meat cooking (4–7%). For PM2.5 composition, the strongest positive associations per IQR were estimated for nitrate, ammonium, and secondary organic aerosols (11–14%), followed by elemental and organic carbon (2–4%). Associations with local traffic emissions were positive only when analyses were restricted to births with residences geocoded at the tax parcel level. Conclusions: In our statewide nested case–control study population, exposures

  8. A study of serum psedocholinesterase levels following diazinon poisoning in relation to liver function-prognostic and therapeutic value

    OpenAIRE

    K. Swarnalatha; B. Surya Prakasa Rao; S. Sharon Sonia

    2016-01-01

    Background: To study serum pseudo-cholinesterase (PChE) levels as an index of liver injury in individuals with diazinon poisoning with or without alcoholism. It gives the knowledge of the therapeutic efficacy and severity of liver dysfunction. Methods: Blood samples were taken from normal male adults as control and PChE is estimated. Blood samples were taken from diazinon poisoning patients from local hospitals on the 1st day and on 5th day for pseudocholinesterase estimation. Another grou...

  9. [Accreditation criteria and quality standards for Poisons centres: development of a quality management system within the Milan Poisons centre].

    Science.gov (United States)

    Della Puppa, Tiziana; Manfrè, Sergio; Grezzi, Marinella

    2006-01-01

    Poisons centres throughout Italy and Europe vary considerably in terms of their institutions and organisation. The European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) has laid down the activities that a poisons centre must carry out, specifying minimum and maximum standards required. These directions allow an evaluation of the service provided. In 2002 Milan Poisons Centre began a project aiming to introduce concepts and methodology proper of the quality systems within poisons centres' institutional activity. Concluded, the project resulted in the centre's certification and the documentation of its procedures: this may now contribute to help define the status and activity of poisons centres in Italy.

  10. Plant Poisoning among Children in Rural Sri Lanka

    Directory of Open Access Journals (Sweden)

    M. B. Kavinda Chandimal Dayasiri

    2017-01-01

    Full Text Available Plant poisoning is a common presentation in paediatric practice and an important cause of preventable mortality and morbidity in Sri Lanka. The burden of plant poisoning is largely underexplored. The current multicenter study based in rural Sri Lanka assessed clinical profiles, poison related factors, clinical management, complications, outcomes, and risk factors associated with plant poisoning in the paediatric age group. Among 325 children, 57% were male with 64% being below five years of age. 99.4% had ingested the poison. Transfer rate was 66.4%. Most had unintentional poisoning. Commonest poison plant was Jatropha circus and poisoning event happened mostly in home garden. 29% of parents practiced harmful first-aid practices. 32% of children had delayed presentations to which the commonest reason was lack of parental concern regarding urgency of seeking medical care. Presence of poisonous plants in home garden was the strongest risk factor for plant poisoning. Mortality rate was 1.2% and all cases had Oleander poisoning. The study revealed the value of community awareness regarding risk factors and awareness among healthcare workers regarding the mostly benign nature of plant poisoning in children in view of limiting incidence of plant poisoning and reducing expenditure on patient management.

  11. Pancreatitis in wild zinc-poisoned waterfowl

    Science.gov (United States)

    Sileo, Louis; Beyer, W. Nelson; Mateo, Rafael

    2003-01-01

    Four waterfowl were collected in the TriState Mining District (Oklahoma, Kansas and Missouri, USA), an area known to be contaminated with lead, cadmium and zinc (Zn). They were part of a larger group of 20 waterfowl collected to determine the exposure of birds to metal contamination at the site. The four waterfowl (three Branta canadensis, one Anas platyrhynchos) had mild to severe degenerative abnormalities of the exocrine pancreas, as well as tissue (pancreas, liver) concentrations of Zn that were considered toxic. The mildest condition was characterized by generalized atrophy of exocrine cells that exhibited cytoplasmic vacuoles and a relative lack of zymogen. The most severe condition was characterized by acini with distended lumens and hyperplastic exocrine tissue that completely lacked zymogen; these acini were widely separated by immature fibrous tissue. Because the lesions were nearly identical to the lesions reported in chickens and captive waterfowl that had been poisoned with ingested Zn, and because the concentrations of Zn in the pancreas and liver of the four birds were consistent with the concentrations measured in Zn-poisoned birds, we concluded that these waterfowl were poisoned by Zn. This may be the first reported case of zinc poisoning in free-ranging wild birds poisoned by environmental Zn.

  12. Hypotension in Severe Dimethoate Self-Poisoning

    Science.gov (United States)

    Davies, James; Roberts, Darren; Eyer, Peter; Buckley, Nick; Eddleston, Michael

    2008-01-01

    Introduction Acute self-poisoning with the organophosphorus (OP) pesticide dimethoate has a human case fatality three-fold higher than poisoning with chlorpyrifos despite similar animal toxicity. The typical clinical presentation of severe dimethoate poisoning is quite distinct from that of chlorpyrifos and other OP pesticides: many patients present with hypotension that progresses to shock and death within 12–48 h post-ingestion. The pathophysiology of this syndrome is not clear. Case reports We present here three patients with proven severe dimethoate poisoning. Clinically, all had inappropriate peripheral vasodilatation and profound hypotension on presentation, which progressed despite treatment with atropine, i.v. fluids, pralidoxime chloride, and inotropes. All died 2.5–32 h post-admission. Continuous cardiac monitoring and quantification of troponin T provided little evidence for a primary cardiotoxic effect of dimethoate. Conclusion Severe dimethoate self-poisoning causes a syndrome characterized by marked hypotension with progression to distributive shock and death despite standard treatments. A lack of cardiotoxicity until just before death suggests that the mechanism is of OP-induced low systemic vascular resistance (SVR). Further invasive studies of cardiac function and SVR, and post-mortem histology, are required to better describe this syndrome and to establish the role of vasopressors and high-dose atropine in therapy. PMID:19003596

  13. Does organophosphate poisoning cause cardiac injury?

    Science.gov (United States)

    Aghabiklooei, Abbas; Mostafazadeh, Babak; Farzaneh, Esmaeil; Morteza, Afsaneh

    2013-11-01

    Organophosphates are insecticides which are widely used as a suicidal agent in Iran. They are associated with different types of cardiac complications including cardiac arrest and arrhythmia, however their role in cardiac injury is not known yet. The aim of this study was to investigate the presence of myocardial damage in patients with cholinesterase poisoning.It was a prospective study conducted from January 2008 to March 2010. Cohorts of patients with cholinesterase poisoning due to suicidal attempt who have been referred to Loghman hospital were selected. Patients who have taken more than one poison or were used concomitant drugs were excluded. Physical examination was performed on admission to discover warning sign. Peripheral arterial blood gases, creatine kinase, creatine kinase-myocardial band, troponin-T measurements were performed in all cases. There were 24 patients, 7 of them women, with the mean age of 41.2±15.05 who were included in this study. Non-survivors had significantly higher levels of systolic blood pressure, partial pressure of oxygen in arterial blood, partial pressure of carbon dioxide, bicarbonate Glasgow Coma Scale scoring and longer duration of mechanical ventilation. Our findings showed that cardiac injury is an important cause of death in organophosphate poisoning. It could be hypothesized that cardiac injury is a strong predictor of death in patients with organophosphate poisoning.

  14. Continental Rupture Controlled by Low-Angle Normal Faults in the Northern Gulf of California: Analysis of Seismic Reflection Profiles

    Science.gov (United States)

    Martin-Barajas, A.; González-Escobar, M.; Fletcher, J. M.; Pacheco, M.; Mar-Hernández, E.

    2010-12-01

    The transition from focused continental extension to the rupture of continental lithosphere is imaged in the northern Gulf of California rift system across the obliquely conjugated Tiburon-Delfin basins. Structural mapping on a 5-20 km grid of seismic reflection lines (48 channels, 6s TWTT) of Petroleos Mexicanos indicates that a large amount of extension and subsidence in the Tiburon basin was accommodated on a NNE-striking pattern of normal faults merging at depth into a detachment fault (here named Angel de la Guarda Detachment or AGD). The main AGD break-away fault is a ~70 km-long, listric fault concave to the southeast, which flattens below 3 seconds (TWTT). This detachment fault juxtaposes the late-Neogene marine sequence over thinned, mostly Mesozoic continental crust. The AGD is bounded at both ends by two major NW-striking, dextral-oblique faults, the Tiburon and De Mar faults that shear the continental crust parallel to the tectonic transport on both margins of the Tiburon basin. Additional, yet undetermined, amount of dextral shear was accommodated in a ~30 to 50 km wide belt adjacent to mainland Sonora along the now inactive eastern margin of the rift. The AGD break-away fault is cut by an array of NE-striking, northwest dipping active normal faults that accommodate oblique extension to the northwest into the Lower and Upper Delfin basins. Both Delfin basins form a broad, tectonically active rombochasm that also contains a ˜7 km-thick late Neogene sedimentary fill largely derived from the Colorado river delta. Intermediate to felsic magmatic intrusions with MORB-type geochemical and isotopic signatures along the western margin of the rift strongly indicate the rupture of the continental lithosphere and formation of an hybrid crust formed by thick sedimentary sequences and magmatic intrusions. We speculate that thermal anomaly caused by the rupture of continental lithosphere in Delfin basins caused footwall uplift of the detachment fault and the intra

  15. The Mountain Meadows Massacre and "poisoned springs": scientific testing of the more recent, anthrax theory.

    Science.gov (United States)

    Perego, Ugo A; Achilli, Alessandro; Ekins, Jayne E; Milani, Lucio; Lari, Martina; Pilli, Elena; Brown, Alexis; Price, Erin P; Wolken, Spenser R; Matthews, Molly; Allen, Christina A; Pearson, Talima R; Angerhofer, Norman; Caramelli, David; Kupferschmid, Tim; Keim, Paul S; Woodward, Scott R

    2013-01-01

    It has been recorded that one of the possible causes that eventually escalated into the 1857 manslaughter at Mountain Meadows in Southern Utah was the poisoning of an open spring by the Fancher-Baker party as they crossed the Utah territory on their way from Arkansas to California. Historical accounts report that a number of cattle died, followed by human casualties from those that came in contact with the dead animals. Even after the Arkansas party departed, animals continued to perish and people were still afflicted by some unknown plague. Proctor Hancock Robison, a local 14-year-old boy, died shortly after skinning one of the "poisoned" cows. A careful review of the historical records, along with the more recent scientific literature, seems to exclude the likelihood of actual poisoning in favor of a more recent theory that would point to the bacterium Bacillus anthracis as the possible cause of human and animal deaths. In order to test this hypothesis, Proctor's remains were exhumed, identified through mitochondrial DNA analysis, and tested for the presence of anthrax spores. Although preliminary testing of remains and soil was negative, description of the clinical conditions that affected Proctor and other individuals does not completely rule out the hypothesis of death by anthrax.

  16. ONE CASE REPORT OF ACUTE POISONING BY BARIUM CARBONATE

    Institute of Scientific and Technical Information of China (English)

    GE Qin-min; BIAN Fan; WANG Shu-yun; SHEN Sheng-hui

    2009-01-01

    @@ Most barium poisoning cases were caused by oral intake by mistake. Recent years, barium carbonate poisoning has been rare to be reported. Here we reported a case of acute barium carbonate toxication taken orally on purpose.

  17. Pot-Laced Goodies Can Poison a Child

    Science.gov (United States)

    ... news/fullstory_164157.html Pot-Laced Goodies Can Poison a Child These pastries and candies pose serious ... to kids -- but eating even one treat might poison them, a leading group of U.S. pediatricians warns. ...

  18. Milia after allergic contact dermatitis from poison ivy: two cases.

    Science.gov (United States)

    Berk, David R; Hurt, Mark A; Reese, Lester T; Wagner, Laura; Bayliss, Susan J

    2010-01-01

    Milia have rarely been reported as a complication of severe allergic contact dermatitis. To our knowledge, milia have not previously been associated with poison ivy dermatitis. We present two cases of milia after allergic contact dermatitis to poison ivy.

  19. Unusual case of methanol poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Shapiro, L.; Henderson, M. (St. James' s Univ. Hospital, Leeds (United Kingdom). Dept. of Chemical Pathology); Madi, S.; Mellor, L. (St. James' s Univ. Hospital, Leeds (United Kingdom). Dept. of Medicine, and Pharmacy)

    1993-01-09

    A 31-year-old man with a history of alcohol abuse presented to the accident and emergency department complaining of blurred vision. 4 h previously he had drunk 300 mL de-icer fluid. Electrolytes, urea, creatinine, glucose, and blood-gas analysis were normal. Measured osmolality, however, was 368 mosmol/kg with a calculated osmolality of 300 mosmol/kg, which indicated a greatly increased osmolar gap. He was therefore given 150 mL whisky and admitted. Methanol was later reported as 200 mg/dL. Ethylene glycol was not detected, but another glycol, propylene glycol, was present at 47 mg/dL. 10 h after ingestion an intravenous infusion of ethanol was started and he was hemodialysed for 7 h. After dialysis he was given a further 100 mL whisky and the rate of ethanol infusion was reduced to 11 g per h. Methanol and ethanol were measured twice daily until methanol was under 10/mg/dL: The recommendation is that blood ethanol be maintained between 100 and 200 mg/dL during treatment of methanol poisoning. This concentration was not achieved, presumably because of the high rate of ethanol metabolism often found in alcoholics. Antifreeze solutions commonly contain methanol and ethylene glycol. Sometimes propylene glycol is substituted because it has properties similar to those of ethylene glycol but is less toxic. The authors postulate that propylene glycol inhibited the metabolism of methanol in the patient, thus sparing him from the toxic effects of methanol.

  20. Brighter-colored paper wasps (Polistes dominula have larger poison glands

    Directory of Open Access Journals (Sweden)

    Vidal-Cordero J

    2012-08-01

    Full Text Available Abstract Introduction Aposematism is a defense system against predators consisting of the toxicity warning using conspicuous coloration. If the toxin production and aposematic coloration is costly, only individuals in good physical condition could simultaneously produce abundant poison and striking coloration. In such cases, the aposematic coloration not only indicates that the animal is toxic, but also the toxicity level of individuals. The costs associated with the production of aposematic coloration would ensure that individuals honestly indicate their toxicity levels. In the present study, we examine the hypothesis that a positive correlation exists between the brightness of warning coloration and toxicity level using as a model the paper wasp (Polistes dominula. Results We collected wasps from 30 different nests and photographed them to measure the brightness of warning coloration in the abdomen. We also measured the volume of the poison gland, as well as the length, and the width of the abdomen. The results show a positive relationship between brightness and poison-gland size, which remained positive even after controlling for the body size and abdomen width. Conclusion The results suggest that the coloration pattern of these wasps is a true sign of toxicity level: wasps with brighter colors are more poisonous (they have larger poison glands.

  1. Ulinastatin suppresses endoplasmic reticulum stress and apoptosis in the hippocampus of rats with acute paraquat poisoning

    Directory of Open Access Journals (Sweden)

    Hai-feng Li

    2015-01-01

    Full Text Available Lung injury is the main manifestation of paraquat poisoning. Few studies have addressed brain damage after paraquat poisoning. Ulinastatin is a protease inhibitor that can effectively stabilize lysosomal membranes, prevent cell damage, and reduce the production of free radicals. This study assumed that ulinastatin would exert these effects on brain tissues that had been poisoned with paraquat. Rat models of paraquat poisoning were intraperitoneally injected with ulinastatin. Simultaneously, rats in the control group were administered normal saline. Hematoxylin-eosin staining showed that most hippocampal cells were contracted and nucleoli had disappeared in the paraquat group. Fewer cells in the hippocampus were concentrated and nucleoli had disappeared in the ulinastatin group. Western blot assay showed that expressions of GRP78 and cleaved-caspase-3 were significantly lower in the ulinastatin group than in the paraquat group. Immunohistochemical findings showed that CHOP immunoreactivity was significantly lower in the ulinastatin group than in the paraquat group. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling staining showed that the number of apoptotic cells was reduced in the paraquat and ulinastatin groups. These data confirmed that endoplasmic reticular stress can be induced by acute paraquat poisoning. Ulinastatin can effectively inhibit this stress as well as cell apoptosis, thereby exerting a neuroprotective effect.

  2. [Contact allergy to Anacardiaceae. A review and case reports of poison ivy allergy in central Europe].

    Science.gov (United States)

    Ippen, H

    1983-01-01

    In Europe, as opposed to North America, poison-ivy rash is hardly known. For this reason a detailed review of the allergenic members of the Anacardiaceae family is given, and the misleading nomenclature of "poison ivy", "poison oak", and some other species of this family are discussed. An up-to-date representation of the chemical structure of the allergenic substance group (denoted as "Urushiol") from this family is provided as well as botanical information regarding the plants themselves. Prevention of this dangerous sensitization and the therapy of this allergic reaction are discussed. The four cases presented are as follows: a young German woman who became sensitized to poison ivy or poison oak while in the USA and showed a cross reaction to other Rhus species (R. copallina, R. javanica (semialata), R. trichocarpa) as well as to Choerospondias axillaris var. japonica and to mangoes; a landscape gardener with an occupationally acquired allergy to Anacardium occidentale; and two control persons giving positive results to skin tests with Urushiol and Rhus trichocarpa respectively, to which the source of sensitization could not be clarified. Tests with three kinds of pistachio and two native-European Anacardiaceae (Rhus typhina and Cotinus coggygria) yielded negative results in each case. Prophylaxis to sensitization requires familiarity with the numerous Anacardiaceae and derivative products to which one could come in contact. These substances, summarized in a table, include mango, cashew and "sweet pepper".

  3. Ulinastatin suppresses endoplasmic reticulum stress and apoptosis in the hippocampus of rats with acute paraquat poisoning

    Institute of Scientific and Technical Information of China (English)

    Hai-feng Li; Shi-xing Zhao; Bao-peng Xing; Ming-li Sun

    2015-01-01

    Lung injury is the main manifestation of paraquat poisoning. Few studies have addressed brain damage after paraquat poisoning. Ulinastatin is a protease inhibitor that can effectively stabilize lysosomal membranes, prevent cell damage, and reduce the production of free radicals. This study assumed that ulinastatin would exert these effects on brain tissues that had been poisoned with paraquat. Rat models of paraquat poisoning were intraperitoneally injected with ulinastatin. Simultaneously, rats in the control group were administered normal saline. Hematoxylin-eosin staining showed that most hippocampal cells were contracted and nucleoli had disappeared in the paraquat group. Fewer cells in the hippocampus were concentrated and nucleoli had dis-appeared in the ulinastatin group. Western blot assay showed that expressions of GRP78 and cleaved-caspase-3 were signiifcantly lower in the ulinastatin group than in the paraquat group. Immunohistochemical ifndings showed that CHOP immunoreactivity was signiifcantly lower in the ulinastatin group than in the paraquat group. Terminal deoxynucleotidyl transferase-medi-ated dUTP nick end labeling staining showed that the number of apoptotic cells was reduced in the paraquat and ulinastatin groups. These data conifrmed that endoplasmic reticular stress can be induced by acute paraquat poisoning. Ulinastatin can effectively inhibit this stress as well as cell apoptosis, thereby exerting a neuroprotective effect.

  4. Experiência bem-sucedida no controle do Aedes aegypti sem uso de venenos no sertão cearense | Successful experience in the control of Aedes aegypti without the use of poisons in Ceará backcountry

    Directory of Open Access Journals (Sweden)

    Fernando Ferreira Carneiro

    2016-05-01

    Full Text Available O Brasil passa por uma emergência de saúde pública e por uma tríplice epidemia de dengue, zika e chikungunya, transmitidas pelo mosquito Aedes aegypti. Estudos atestam a ineficácia do modelo convencional de controle do vetor adotado há mais de 30 anos. Apresentamos a experiência do município de Pedra Branca no sertão do Ceará, que rompeu com o paradigma de combate ao vetor centrado no controle químico hegemônico no Brasil. O município obteve êxito nas suas ações de controle vetorial, apresentando ausência de transmissão local de dengue há mais de dez anos, alcançando no ano de 2016 por seis meses 0,09% de índice de infestação predial por Aedes aegypti. Esse resultado é fruto de um trabalho de cerca de 15 anos que vem sendo mantido pelas sucessivas gestões municipais, as quais destacamos: visitas mensais dos agentes de combate de endemias; ovitrampas; monitoramento ambiental; vedação de reservatórios; controle biológico; delimitação de focos; educação em saúde; integração da Estratégia Saúde da Família com agentes de combate de endemias e a Secretaria de Educação; e apoio da gestão municipal como um todo. A experiência desse município aponta para formas mais efetivas e sustentáveis, podendo subsidiar ações de enfrentamento da tríplice epidemia a serem implementadas em outros sistemas municipais de saúde. -------------------------------------------------------------------------------------------- Brazil is going through a public health emergency and a triple epidemic of Dengue, Chikungunya and Zika, transmitted by the Aedes aegypti mosquito. Studies attested the inefficacy of conventional model of vector control used for over 30 years. The experience of the city of Pedra Branca in the backcountry of the state of Ceará, which broke with the hegemonic paradigm of chemical control for the vector-centered combat in Brazil, is presented. The council was successful in its vector control activities

  5. Acute Anterolateral Myocardial Infarction Due to Aluminum Phosphide Poisoning

    Directory of Open Access Journals (Sweden)

    Bita Dadpour

    2013-08-01

    Full Text Available Aluminum phosphide (AlP is a highly effective rodenticide which is used as a suicide poison. Herein, a 24 year-old man who’d intentionally ingested about 1liter of alcohol and one tablet of AlP is reported. Acute myocardial infarction due to AlP poisoning has been occurred secondary to AIP poisoning. Cardiovascular complications are poor prognostic factors in AlP poisoning

  6. [Effect of mercuric chloride poisoning on iron distribution in rats].

    Science.gov (United States)

    Grosicki, A; Kossakowski, S

    1990-01-01

    The aim of our work was to establish the influence of the HgCl2 poisoning (various doses) on the Fe distribution in the rat organism. 175 Wistar rats were divided into 5 groups: I--control group, II--intoxicated with HgCl2 in the dose of 1 mg/kg of body weight, in the III group the HgCl2 dose was 6 mg/kg, in the IV group--12 mg/kg, in the V--12 mg/kg but rats of this group were given afterwards BAL (2.3-dimercaptopropanol). All rats were given 0.2 ml of 59FeCl3, radioactivity 3.7 kBq. The animals were put to sleep with chloroform after 3 and 6 hours, and 1, 2, 4, 8, 14 days after the isotope administration. For the radiometric assays the following organs or tissues were taken: stomach, small and large intestine, liver, kidneys, lungs, heart, muscles, spleen, blood, brain, testicles. The results are given in the percent of Fe dose in 1 g of wet tissue. The statistical analysis (Students' t test) was performed. The results indicate that in poisoned animals the Fe distribution was different than in controls. Increased concentration of 59Fe was noted after 3 and 6 hours in stomach and after 1 day in large intestine, whereas in other organs the Fe concentration was lower, correlating usually with the Hg dose. One interesting thing was noted: the Fe concentration in almost all organs was higher in rats intoxicated with the 12 mg/kg dose of HgCl2 and given afterwards BAL (IV group), than in rats that were not given BAL. Present results can have some practical significance in therapeutic procedure in mercury poisoning and during the convalescence.

  7. Fatal poisoning among patients with drug addiction

    DEFF Research Database (Denmark)

    Simonsen, Kirsten Wiese; Christoffersen, Dorte J; Banner, Jytte

    2015-01-01

    INTRODUCTION: Fatal poisonings among drug addicts in Denmark in 2012 were examined. Cause of death, abuse pattern and geographic differences are discussed and data are compared with previous studies. METHODS: All fatal poisonings examined at the three institutes of forensic medicine in Denmark......%) continued, declining to 44% in 2002, 33% in 2007 and finally to 27% in 2012. Few deaths from central stimulants (amphetamine and cocaine) occurred. Multiple drug use was common and consisted mainly of opioids, cocaine, amphetamine, cannabis, benzodiazepines and alcohol. Heroin/morphine use was most frequent...... on Funen and in South Jutland. Cocaine was most frequently detected in East Denmark, while amphetamine was more frequent in West Denmark. CONCLUSIONS: The number of fatal poisonings among drug addicts has stabilised around 200. The increase in methadone deaths continued and, as in 2007, methadone...

  8. Zebrafish Models for Human Acute Organophosphorus Poisoning.

    Science.gov (United States)

    Faria, Melissa; Garcia-Reyero, Natàlia; Padrós, Francesc; Babin, Patrick J; Sebastián, David; Cachot, Jérôme; Prats, Eva; Arick Ii, Mark; Rial, Eduardo; Knoll-Gellida, Anja; Mathieu, Guilaine; Le Bihanic, Florane; Escalon, B Lynn; Zorzano, Antonio; Soares, Amadeu M V M; Raldúa, Demetrio

    2015-10-22

    Terrorist use of organophosphorus-based nerve agents and toxic industrial chemicals against civilian populations constitutes a real threat, as demonstrated by the terrorist attacks in Japan in the 1990 s or, even more recently, in the Syrian civil war. Thus, development of more effective countermeasures against acute organophosphorus poisoning is urgently needed. Here, we have generated and validated zebrafish models for mild, moderate and severe acute organophosphorus poisoning by exposing zebrafish larvae to different concentrations of the prototypic organophosphorus compound chlorpyrifos-oxon. Our results show that zebrafish models mimic most of the pathophysiological mechanisms behind this toxidrome in humans, including acetylcholinesterase inhibition, N-methyl-D-aspartate receptor activation, and calcium dysregulation as well as inflammatory and immune responses. The suitability of the zebrafish larvae to in vivo high-throughput screenings of small molecule libraries makes these models a valuable tool for identifying new drugs for multifunctional drug therapy against acute organophosphorus poisoning.

  9. Toxicological criterion of the heroin poisoning.

    Science.gov (United States)

    Shigeev, S

    2007-01-01

    The paper presents toxicological characteristics of 198 cases of acute parenteral heroin intoxication, analyzes the clinically encountered range of blood and urinary concentrations of its metabolites. The principal causes of death are elucidated in victims of heroin poisoning at the hospital stage. Where there is a relationship of death probability to the detection of morphine in the victims' biological fluids is considered; its blood and urinary concentrations are determined, which undoubtedly suggests the occurrence of poisoning-related death. It has been established that death from poisoning by heroin may occur in the whole range of its detectable concentrations. There is no doubt that the blood morphine concentrations of at least 2.0 microg/ml should be considered to be fatal.

  10. Linking cases of illegal shootings of the endangered California condor using stable lead isotope analysis

    Energy Technology Data Exchange (ETDEWEB)

    Finkelstein, Myra E., E-mail: myraf@ucsc.edu [Microbiology and Environmental Toxicology Department, University of California, Santa Cruz, CA 95064 (United States); Kuspa, Zeka E. [Microbiology and Environmental Toxicology Department, University of California, Santa Cruz, CA 95064 (United States); Welch, Alacia [National Park Service, Pinnacles National Park, 5000 Highway 146, Paicines, CA 95043 (United States); Eng, Curtis; Clark, Michael [Los Angeles Zoo and Botanical Gardens, 5333 Zoo Drive, Los Angeles, CA 90027 (United States); Burnett, Joseph [Ventana Wildlife Society, 19045 Portola Dr. Ste. F-1, Salinas, CA 93908 (United States); Smith, Donald R. [Microbiology and Environmental Toxicology Department, University of California, Santa Cruz, CA 95064 (United States)

    2014-10-15

    Lead poisoning is preventing the recovery of the critically endangered California condor (Gymnogyps californianus) and lead isotope analyses have demonstrated that ingestion of spent lead ammunition is the principal source of lead poisoning in condors. Over an 8 month period in 2009, three lead-poisoned condors were independently presented with birdshot embedded in their tissues, evidencing they had been shot. No information connecting these illegal shooting events existed and the timing of the shooting(s) was unknown. Using lead concentration and stable lead isotope analyses of feathers, blood, and recovered birdshot, we observed that: i) lead isotope ratios of embedded shot from all three birds were measurably indistinguishable from each other, suggesting a common source; ii) lead exposure histories re-constructed from feather analysis suggested that the shooting(s) occurred within the same timeframe; and iii) two of the three condors were lead poisoned from a lead source isotopically indistinguishable from the embedded birdshot, implicating ingestion of this type of birdshot as the source of poisoning. One of the condors was subsequently lead poisoned the following year from ingestion of a lead buckshot (blood lead 556 µg/dL), illustrating that ingested shot possess a substantially greater lead poisoning risk compared to embedded shot retained in tissue (blood lead ∼20 µg/dL). To our knowledge, this is the first study to use lead isotopes as a tool to retrospectively link wildlife shooting events. - Highlights: • We conducted a case-based analysis of illegal shootings of California condors. • Blood and feather Pb isotopes were used to reconstruct the illegal shooting events. • Embedded birdshot from the three condors had the same Pb isotope ratios. • Feather and blood Pb isotopes indicated that the condors were shot in a common event. • Ingested shot causes substantially greater lead exposure compared to embedded shot.

  11. Detection of neutrophil-lymphocyte ratio as a serum marker associated with inlfammations by acute carbon monoxide poisoning

    Institute of Scientific and Technical Information of China (English)

    Mustafa Karabacak; Kenan Ahmet Turkdogan; Abuzer Coskun; Orhan Akpinar; Ali Duman; Mcahit Kapci; Sevki Hakan Eren; Pnar Karabacak

    2015-01-01

    Objective: To investigate neutrophil–lymphocyte ratio (NLR), which is an indicator of systemic inflammation, in patients with carbon monoxide (CO) poisoning. Methods: We included 528 patients (275 women) who presented with a diagnosis of CO poisoning between June 2009 and March 2014. Control group was composed of 54 patients (24 women). Platelet count and mean platelet volume level were significantly higher in the CO poisoning group. Results: White blood cell level (9.8 ± 3.3vs 8.6 ± 2.9× 103/mL, respectively;P= 0.01), neutrophil count (6.00 ± 2.29vs 4.43 ± 2.04×103/mL, respectively;P Conclusions: The increase ofNLR may indicate the progression of fatal complications due to CO poisoning.

  12. [Chronic lead poisoning in children today. A pathology of poverty and social exclusion].

    Science.gov (United States)

    Sinnaeve, O; Berthier, M; Guillard, O; Perault, M C; Oriot, D

    1999-07-01

    Despite the recognition of lead poisoning in children as a major public health problem in France since the 1980's, the setting-up of systematic detection of lead poisoning at a national level has not yet been done. The main source of intoxication in children is in paintings containing ceruse in housing built before 1948. Moderate chronic poisoning, although leading to irreversible lesions, particularly of the central nervous system, remains usually unnoticed. The biological diagnosis is mainly based upon blood lead level, completed by the protoporphyrine-zinc level. Large scale identification of dangerous housing and the control of rehabilitation are the only means available to decrease the incidence of lead posioning. Targeted screening is difficult because it concerns children excluded from classical health care systems. Prevention and long-term treatment requires elimination of the source of lead intoxication after an environmental inquiry. This raises the problems of rehousing and follow-up of intoxicated children.

  13. Fight Homemade Poisons: Home Food Care and Preservation.

    Science.gov (United States)

    Keller, Rosanne

    One of a series of instructional materials produced by the Literacy Council of Alaska, this booklet provides information about food poisoning. Using a simplified vocabulary and shorter sentences, it explains the various kinds of food poisoning, how people get food poisoning, and how to prevent it. (FL)

  14. CLINICAL PROFILE OF CHILDHOOD POISONING IN A TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Poornima

    2016-03-01

    Full Text Available BACKGROUND Accidents including poisoning are one of the leading causes of morbidity and mortality among children in the west. Poisoning, while never accounting for a large number of accidental deaths, have acquired prominence now because they have not decreased at the same rate as the infectious diseases. METHODS An observational study was done in Department of Paediatrics KIMS Bangalore to know the incidence and pattern of childhood poisoning, to know the morbidity and mortality resulting from childhood poisoning. 86 children aged between 0-18 years were admitted to the paediatric intensive care unit with history of poisoning during the 2-year period of the study (Nov 13-Nov 15 were included. Diagnosis of poisoning was made on the basis of history and examination findings, Relevant investigations were done and Profile of patients with poisoning, their symptoms, type of poisoning and outcome were analysed. RESULTS The average duration of stay in the hospital was 2.7 days. Poisoning was accidental in 80 (93% patients whereas suicidal intent was present in only 6 (7% patients. Total 5 (5.8% patients died of which 4 were due to insecticide and pesticide poisoning and one was due to kerosene poisoning. CONCLUSION In the present study the probable reason for higher incidence of poisoning by insecticides & pesticides could be the involvement of higher age group and more involvement of adolescent children.

  15. 76 FR 16521 - National Poison Prevention Week, 2011

    Science.gov (United States)

    2011-03-23

    ... March 23, 2011 Part III The President Proclamation 8638--National Poison Prevention Week, 2011 #0; #0..., 2011 National Poison Prevention Week, 2011 By the President of the United States of America A... cases, these tragic incidents are preventable. During National Poison Prevention Week, I encourage...

  16. 78 FR 17069 - National Poison Prevention Week, 2013

    Science.gov (United States)

    2013-03-20

    ... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8940 of March 15, 2013 National Poison..., Americans have marked National Poison Prevention Week by highlighting the steps we can take to protect... encouraging common-sense precautions and raising awareness about how to respond in a poison emergency....

  17. 49 CFR 172.555 - POISON INHALATION HAZARD placard.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON INHALATION HAZARD placard. 172.555 Section... REQUIREMENTS, AND SECURITY PLANS Placarding § 172.555 POISON INHALATION HAZARD placard. (a) Except for size and color, the POISON INHALATION HAZARD placard must be as follows: ER22JY97.025 (b) In addition...

  18. 49 CFR 172.429 - POISON INHALATION HAZARD label.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false POISON INHALATION HAZARD label. 172.429 Section... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.429 POISON INHALATION HAZARD label. (a) Except for size and color, the POISON INHALATION HAZARD label must be as follows: ER22JY97.023 (b) In addition to...

  19. 77 FR 16645 - National Poison Prevention Week, 2012

    Science.gov (United States)

    2012-03-21

    ... March 21, 2012 Part III The President Proclamation 8784--National Poison Prevention Week, 2012... Poison Prevention Week, 2012 By the President of the United States of America A Proclamation... thousands of lives every year. On the 50th anniversary of National Poison Prevention Week, I encourage...

  20. Development of Optimized Guidelines for Therapeutic Strategies for Organophosphate Poisoning

    Science.gov (United States)

    2011-03-01

    STRATEGIES FOR ORGANOPHOSPHATE POISONING THESIS Craig A. Holder, Captain, USAF AFIT/GIH/ENV/11-M02 DEPARTMENT OF THE AIR FORCE AIR...THERAPEUTIC STRATEGIES FOR ORGANOPHOSPHATE POISONING THESIS Presented to the Faculty Department of Systems and Engineering Management...STRATEGIES FOR ORGANOPHOSPHATE POISONING Craig A. Holder, BS Captain, USAF Approved: //signed