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Sample records for california mice peromyscus

  1. Individual variation in paternal responses of virgin male California mice (Peromyscus californicus): behavioral and physiological correlates

    NARCIS (Netherlands)

    T.R. de Jong; A. Korosi; B.N. Harris; J.P. Perea-Rodriguez; W. Saltzman

    2012-01-01

    California mice Peromyscus californicus are a rodent species in which fathers provide extensive paternal care; however, behavioral responses of virgin males toward conspecific neonates vary from paternal behavior to tolerance to infanticide. Indirect evidence suggests that paternal responses might b

  2. Differences in ultrasonic vocalizations between wild and laboratory California mice (Peromyscus californicus.

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    Matina C Kalcounis-Rueppell

    Full Text Available BACKGROUND: Ultrasonic vocalizations (USVs emitted by muroid rodents, including laboratory mice and rats, are used as phenotypic markers in behavioral assays and biomedical research. Interpretation of these USVs depends on understanding the significance of USV production by rodents in the wild. However, there has never been a study of muroid rodent ultrasound function in the wild and comparisons of USVs produced by wild and laboratory rodents are lacking to date. Here, we report the first comparison of wild and captive rodent USVs recorded from the same species, Peromyscus californicus. METHODOLOGY AND PRINCIPAL FINDINGS: We used standard ultrasound recording techniques to measure USVs from California mice in the laboratory (Peromyscus Genetic Stock Center, SC, USA and the wild (Hastings Natural History Reserve, CA, USA. To determine which California mouse in the wild was vocalizing, we used a remote sensing method that used a 12-microphone acoustic localization array coupled with automated radio telemetry of all resident Peromyscus californicus in the area of the acoustic localization array. California mice in the laboratory and the wild produced the same types of USV motifs. However, wild California mice produced USVs that were 2-8 kHz higher in median frequency and significantly more variable in frequency than laboratory California mice. SIGNIFICANCE: The similarity in overall form of USVs from wild and laboratory California mice demonstrates that production of USVs by captive Peromyscus is not an artifact of captivity. Our study validates the widespread use of USVs in laboratory rodents as behavioral indicators but highlights that particular characteristics of laboratory USVs may not reflect natural conditions.

  3. The pox in the North American backyard: Volepox virus pathogenesis in California mice (Peromyscus californicus.

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    Nadia F Gallardo-Romero

    Full Text Available Volepox virus (VPXV was first isolated in 1985 from a hind foot scab of an otherwise healthy California vole (Microtus californicus. Subsequent surveys in San Mateo County, CA, revealed serological evidence suggesting that VPXV is endemic to this area, and a second viral isolate from a Pinyon mouse (Peromyscus truei was collected in 1988. Since then, few studies have been conducted regarding the ecology, pathology, and pathogenicity of VPXV, and its prevalence and role as a potential zoonotic agent remain unknown. To increase our understanding of VPXV disease progression, we challenged 24 California mice (Peromyscus californicus intranasally with 1.6 × 10(3 PFU of purified VPXV. By day five post infection (pi we observed decreased activity level, conjunctivitis, ruffled hair, skin lesions, facial edema, and crusty noses. A mortality rate of 54% was noted by day eight pi. In addition, internal organ necrosis and hemorrhages were observed during necropsy of deceased or euthanized animals. Viral loads in tissues (brain, gonad, kidney, liver, lung, spleen, submandibular lymph node, and adrenal gland, bodily secretions (saliva, and tears, and excretions (urine, and/or feces were evaluated and compared using real time-PCR and tissue culture. Viral loads measured as high as 2 × 10(9 PFU/mL in some organs. Our results suggest that VPXV can cause extreme morbidity and mortality within rodent populations sympatric with the known VPXV reservoirs.

  4. Paternal responsiveness is associated with, but not mediated by reduced neophobia in male California mice (Peromyscus californicus)

    OpenAIRE

    Chauke, Miyetani; de Jong, Trynke R.; Garland, Theodore; Saltzman, Wendy

    2012-01-01

    Hormones associated with pregnancy and parturition have been implicated in facilitating the onset of maternal behavior via reductions in neophobia, anxiety, and stress responsiveness. To determine whether the onset of paternal behavior has similar associations in biparental male California mice (Peromyscus californicus), we compared paternal responsiveness, neophobia (novel-object test), and anxiety-like behavior (elevated plus maze, EPM) in isolated virgins (housed alone), paired virgins (ho...

  5. Social isolation increases cell proliferation in male and cell survival in female California mice (Peromyscus californicus).

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    Ruscio, Michael G; Bradley King, S; Haun, Harold L

    2015-11-01

    Social environment has direct effects on an animal's behavior, physiology and neurobiology. In particular, adult neurogenesis is notably affected by a variety of social manipulations, including social isolation. We hypothesized that social isolation should have particularly acute effects on neurogenesis in a highly social (monogamous and bi-parental) species such as Peromyscus californicus, the California mouse. Adult male and female P. californicus mice were housed in isolation or in same-sex pairs for 4 or 24 days. At the end of each period, either cell proliferation or cell survival was quantified with BrdU label and neuronal markers (either TuJ1 or NeuN). After 4 days, isolated males had greater cellular proliferation in the dentate gyrus of the hippocampus (DG) than pair housed males. After 24 days, isolate females demonstrated greater cell survival in the DG than paired females. Males demonstrated a similar, but non-significant pattern. No differences in cellular proliferation or cell survival were found in the subventricular zone (SVZ), or medial amygdala (MeA). These results add to the evidence which demonstrates that neurogenic responses to environmental conditions are not identical across species. These data may be critical in understanding the functional significance of neurogenesis as it relates to the interactions between social systems, social environment and the display of social behaviors. PMID:26342752

  6. Physiological and neuroendocrine responses to chronic variable stress in male California mice (Peromyscus californicus): influence of social environment and paternal state

    OpenAIRE

    De Jong, TR; Harris, BN; Perea-Rodriguez, JP; Saltzman, W

    2013-01-01

    Social environment and parental state affect stress responses in mammals, but their impact may depend on the social and reproductive strategy of the species. The influences of cohabitation with a male or female conspecific, and the birth of offspring, on the physiological and endocrine responses to chronic variable stress were studied in the monogamous and biparental California mouse (Peromyscus californicus). Adult male California mice were housed either with a male cage ma...

  7. Effects of developmental bisphenol A exposure on reproductive-related behaviors in California mice (Peromyscus californicus: a monogamous animal model.

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    Scott A Williams

    Full Text Available Bisphenol A (BPA, a pervasive, endocrine disrupting compound (EDC, acts as a mixed agonist-antagonist with respect to estrogens and other steroid hormones. We hypothesized that sexually selected traits would be particularly sensitive to EDC. Consistent with this concept, developmental exposure of males from the polygynous deer mouse, Peromyscus maniculatus, to BPA resulted in compromised spatial navigational ability and exploratory behaviors, while there was little effect on females. Here, we have examined a related, monogamous species, the California mouse (Peromyscus californicus, where we predicted that males would be less sensitive to BPA in terms of navigational and exploratory behaviors, while displaying other traits related to interactions with females and territorial marking that might be vulnerable to disruption. As in the deer mouse experiments, females were fed either a phytoestrogen-free CTL diet through pregnancy and lactation or the same diet supplemented with BPA (50 mg/kg feed weight or ethinyl estradiol (EE (0.1 part per billion to provide a "pure" estrogen control. After weaning, pups were maintained on CTL diet until they had reached sexual maturity, at which time behaviors were evaluated. In addition, territorial marking was assessed in BPA-exposed males housed alone and when a control male was visible in the testing arena. In contrast to deer mice, BPA and EE exposure had no effect on spatial navigational skills in either male or female California mice. While CTL females exhibited greater exploratory behavior than CTL males, BPA exposure abolished this sex difference. BPA-exposed males, however, engaged in less territorial marking when CTL males were present. These studies demonstrate that developmental BPA exposure can disrupt adult behaviors in a sex- and species-dependent manner and are consistent with the hypothesis that sexually selected traits are particularly vulnerable to endocrine disruption and should be a

  8. Paternal responsiveness is associated with, but not mediated by reduced neophobia in male California mice (Peromyscus californicus).

    Science.gov (United States)

    Chauke, Miyetani; de Jong, Trynke R; Garland, Theodore; Saltzman, Wendy

    2012-08-20

    Hormones associated with pregnancy and parturition have been implicated in facilitating the onset of maternal behavior via reductions in neophobia, anxiety, and stress responsiveness. To determine whether the onset of paternal behavior has similar associations in biparental male California mice (Peromyscus californicus), we compared paternal responsiveness, neophobia (novel-object test), and anxiety-like behavior (elevated plus maze, EPM) in isolated virgins (housed alone), paired virgins (housed with another male), expectant fathers (housed with pregnant pairmate), and new fathers (housed with pairmate and pups). Corticotropin-releasing hormone (CRH) and Fos immunoreactivity (IR) were quantified in brain tissues following exposure to a predator-odor stressor or under baseline conditions. New fathers showed lower anxiety-like behavior than expectant fathers and isolated virgins in EPM tests. In all housing conditions, stress elevated Fos-IR in the hypothalamic paraventricular nucleus (PVN). Social isolation reduced overall (baseline and stress-induced) Fos- and colocalized Fos/CRH-IR, and increased overall CRH-IR, in the PVN. In the central nucleus of the amygdala, social isolation increased stress-induced CRH-IR and decreased stress-induced activation of CRH neurons. Across all housing conditions, paternally behaving males displayed more anxiety-related behavior than nonpaternal males in the EPM, but showed no differences in CRH- or Fos-IR. Finally, the latency to engage in paternal behavior was positively correlated with the latency to approach a novel object. These results suggest that being a new father does not reduce anxiety, neophobia, or neural stress responsiveness. Low levels of neophobia, however, were associated with, but not necessary for paternal responsiveness. PMID:22634280

  9. Differences in Ultrasonic Vocalizations between Wild and Laboratory California Mice (Peromyscus californicus)

    OpenAIRE

    Kalcounis-Rueppell, Matina C.; Petric, Radmila; Briggs, Jessica R.; Carney, Catherine; Marshall, Matthew M.; Willse, John T.; Rueppell, Olav; Ribble, David O.; Crossland, Janet P.

    2010-01-01

    Background Ultrasonic vocalizations (USVs) emitted by muroid rodents, including laboratory mice and rats, are used as phenotypic markers in behavioral assays and biomedical research. Interpretation of these USVs depends on understanding the significance of USV production by rodents in the wild. However, there has never been a study of muroid rodent ultrasound function in the wild and comparisons of USVs produced by wild and laboratory rodents are lacking to date. Here, we report the first com...

  10. Effects of reproductive experience on central expression of progesterone, oestrogen α, oxytocin and vasopressin receptor mRNA in male California mice (Peromyscus californicus)

    OpenAIRE

    Perea-Rodriguez, JP; Takahashi, EY; Amador, TM; Hao, RC; Saltzman, W; Trainor, BC

    2015-01-01

    © 2015 British Society for Neuroendocrinology. Fatherhood in biparental mammals is accompanied by distinct neuroendocrine changes in males, involving some of the same hormones involved in maternal care. In the monogamous, biparental California mouse (Peromyscus californicus), paternal care has been linked to changes in the central and/or peripheral availability of oestrogen, progesterone, vasopressin and oxytocin, although it is not known whether these endocrine fluctuations are associated wi...

  11. Physiological and neuroendocrine responses to chronic variable stress in male California mice (Peromyscus californicus): Influence of social environment and paternal state.

    Science.gov (United States)

    De Jong, T R; Harris, B N; Perea-Rodriguez, J P; Saltzman, W

    2013-10-01

    Social environment and parental state affect stress responses in mammals, but their impact may depend on the social and reproductive strategy of the species. The influences of cohabitation with a male or female conspecific, and the birth of offspring, on the physiological and endocrine responses to chronic variable stress were studied in the monogamous and biparental California mouse (Peromyscus californicus). Adult male California mice were housed either with a male cage mate (virgin males, VM), a female cage mate (pair-bonded males, PBM), or a female cage mate and their first newborn litter (new fathers, NF). VM, PBM and NF underwent a 7-day chronic variable stress paradigm (CVS, three stressors per day at semi-random times, n=7-8 per housing condition). Compared to control males (CON, n=6-7 per housing condition), CVS caused loss of body mass, increased basal plasma corticosterone concentrations, and increased basal expression of arginine vasopressin (AVP) mRNA in the paraventricular nucleus of the hypothalamus (PVN). These effects were independent of housing condition. Neither CVS nor housing condition altered novel-stressor-induced corticosterone release, spleen or testis mass, or basal expression of corticotropin-releasing hormone (CRH) mRNA in the PVN. Although CVS appeared to increase adrenal mass and reduce thymus mass specifically in NF, these effects were explained by the lower adrenal mass and higher thymus mass of NF compared to PBM and VM under control conditions. These results suggest that neither engaging in a pair bond nor becoming a father attenuates typical responses to CVS, but that fatherhood may provide a buffer against transient mild stressors (i.e., weighing and blood sampling in the control groups) in this monogamous and biparental rodent. PMID:23582312

  12. From here to paternity: neural correlates of the onset of paternal behavior in California mice (Peromyscus californicus).

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    de Jong, Trynke R; Chauke, Miyetani; Harris, Breanna N; Saltzman, Wendy

    2009-08-01

    In a minority of mammalian species, including humans, fathers play a significant role in infant care. Compared to maternal behavior, the neural and hormonal bases of paternal care are poorly understood. We analyzed behavioral, neuronal and neuropeptide responses towards unfamiliar pups in biparental California mice, comparing males housed with another male ("virgin males") or with a female before ("paired males") or after ("new fathers") the birth of their first litter. New fathers approached pups more rapidly and spent more time engaging in paternal behavior than virgin males. In each cage housing two virgin males, one was spontaneously paternal and one was not. New fathers and paired males spent more time sniffing and touching a wire mesh ball containing a newborn pup than virgin males. Only new fathers showed significantly increased Fos-like immunoreactivity in the medial preoptic nucleus (MPO) following exposure to a pup-containing ball, as compared to an empty ball. Moreover, Fos-LIR in the bed nucleus of the stria terminalis (STMV and STMPM) and caudal dorsal raphe nucleus (DRC) was increased in new fathers, independent of test condition. No differences were found among the groups in Fos-LIR in oxytocinergic or vasopressinergic neurons. These results suggest that sexual and paternal experiences facilitate paternal behavior, but other cues play a role as well. Paternal experience increases Fos-LIR induced by distal pup cues in the MPO, but not in oxytocin and vasopressin neurons. Fatherhood also appears to alter neurotransmission in the BNST and DRC, regions implicated in emotionality and stress-responsiveness. PMID:19433091

  13. Effects of reproductive experience on central expression of progesterone, oestrogen α, oxytocin and vasopressin receptor mRNA in male California mice (Peromyscus californicus).

    Science.gov (United States)

    Perea-Rodriguez, J P; Takahashi, E Y; Amador, T M; Hao, R C; Saltzman, W; Trainor, B C

    2015-04-01

    Fatherhood in biparental mammals is accompanied by distinct neuroendocrine changes in males, involving some of the same hormones involved in maternal care. In the monogamous, biparental California mouse (Peromyscus californicus), paternal care has been linked to changes in the central and/or peripheral availability of oestrogen, progesterone, vasopressin and oxytocin, although it is not known whether these endocrine fluctuations are associated with changes in receptor availability in the brain. Thus, we compared mRNA expression of oestrogen receptor (ER)α, progesterone receptor (PR), vasopressin receptor (V1a) and oxytocin receptor (OTR) in brain regions implicated in paternal care [i.e. medial preoptic area (MPOA)], fear [i.e. medial amygdala (MeA)] and anxiety [i.e. bed nucleus of the stria terminalis (BNST)] between first-time fathers (n = 8) and age-matched virgin males (n = 7). Males from both reproductive conditions behaved paternally towards unrelated pups, whereas fathers showed significantly shorter latencies to behave paternally and less time investigating pups. Furthermore, fathers showed significantly lower PR, OTR and V1a receptor mRNA expression in the BNST compared to virgins. Fathers also showed a marginally significant (P = 0.07) reduction in progesterone receptor mRNA expression in the MPOA, although fatherhood was not associated with any other changes in receptor mRNA in the MPOA or MeA. The results of the present study indicate that behavioural and endocrine changes associated with the onset of fatherhood, and/or with cohabitation with a (breeding) female, are accompanied by changes in mRNA expression of hormone and neuropeptide receptors in the brain. PMID:25659593

  14. The biology and methodology of assisted reproduction in deer mice (Peromyscus maniculatus)

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    Veres, Monika; Duselis, Amanda R.; Graft, Audrey; Pryor, William; Crossland, Janet; Vrana, Paul B.; Szalai, Gabor

    2011-01-01

    Although laboratory-reared species of the genus Peromyscus - including deer mice - are used as model animals in a wide range of research, routine manipulation of Peromyscus embryogenesis and reproduction has been lagging. The objective of the present study was to optimize conditions for oocyte/embryo retrieval and for in vitro culturing. On average, 6.4 oocytes per mouse were recovered when two doses of 15 IU of PMSG was given 24 h apart, followed by 15 IU of hCG 48 h later. Following this ho...

  15. Sex differences in social interaction behavior following social defeat stress in the monogamous California mouse (Peromyscus californicus.

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    Brian C Trainor

    Full Text Available Stressful life experiences are known to be a precipitating factor for many mental disorders. The social defeat model induces behavioral responses in rodents (e.g. reduced social interaction that are similar to behavioral patterns associated with mood disorders. The model has contributed to the discovery of novel mechanisms regulating behavioral responses to stress, but its utility has been largely limited to males. This is disadvantageous because most mood disorders have a higher incidence in women versus men. Male and female California mice (Peromyscus californicus aggressively defend territories, which allowed us to observe the effects of social defeat in both sexes. In two experiments, mice were exposed to three social defeat or control episodes. Mice were then behaviorally phenotyped, and indirect markers of brain activity and corticosterone responses to a novel social stimulus were assessed. Sex differences in behavioral responses to social stress were long lasting (4 wks. Social defeat reduced social interaction responses in females but not males. In females, social defeat induced an increase in the number of phosphorylated CREB positive cells in the nucleus accumbens shell after exposure to a novel social stimulus. This effect of defeat was not observed in males. The effects of defeat in females were limited to social contexts, as there were no differences in exploratory behavior in the open field or light-dark box test. These data suggest that California mice could be a useful model for studying sex differences in behavioral responses to stress, particularly in neurobiological mechanisms that are involved with the regulation of social behavior.

  16. Consequences of Fatherhood in the Biparental California Mouse (Peromyscus californicus): Locomotor Performance, Metabolic Rate, and Organ Masses.

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    Andrew, Jacob R; Saltzman, Wendy; Chappell, Mark A; Garland, Theodore

    2016-01-01

    Although effects of motherhood on mothers have been well documented in mammals, the effects of fatherhood on fathers are not well known. We evaluated effects of being a father on key metabolic and performance measures in the California mouse, Peromyscus californicus. California mice are genetically monogamous in the wild, and fathers show similar parental behavior to mothers, with the exception of lactation. To investigate the impact of fatherhood on fathers, focal males were paired with an intact female (breeding males), a tubally ligated female (nonbreeding males), or another male (virgins). Starting 3-5 d after the birth of each breeding pair's first litter, males were tested for locomotor performance (maximum sprint speed, treadmill endurance), basal metabolic rate (BMR), and maximum oxygen consumption ([Formula: see text]). At the end of the 11-d test period, mice were euthanized, hematocrit was determined, and organs were weighed. Speed, endurance, and [Formula: see text] were significantly repeatable between two replicate measurement days but did not differ among groups, nor did BMR. Breeding males had significantly larger hind limb muscles than did nonbreeding males, whereas virgin males had heavier subcutaneous fat pads than did nonbreeding and breeding males. Several correlations were observed at the level of individual variation (residuals from ANCOVA models), including positive correlations for endurance with [Formula: see text], [Formula: see text] with testes mass, and some of the digestion-related organs with each other. These results indicate that fatherhood may not have pronounced performance, metabolic, or morphological effects on fathers, at least under standard laboratory conditions and across a single breeding cycle. PMID:27082723

  17. Photoperiodic Regulation of Cerebral Blood Flow in White-Footed Mice (Peromyscus leucopus).

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    Borniger, Jeremy C; Teplitsky, Seth; Gnyawali, Surya; Nelson, Randy J; Rink, Cameron

    2016-01-01

    Individuals living outside the tropics need to adjust their behavioral and physiological repertoires throughout the year to adapt to the changing seasons. White-footed mice (Peromyscus leucopus) reduce hippocampal volumes, hippocampal-dependent memory function, long-term potentiation, and alter neurogenesis in response to short (winter-like) day lengths (photoperiods). During winter, these mice putatively shunt energy away from the brain to maximize peripheral thermogenesis, immune function, and survival. We hypothesized that these changes in brain function are accompanied by alterations in brain vasculature. We maintained white-footed mice in short (8 h light/16 h dark) or long (16 h light/8 h dark) photoperiods for 8-9 weeks. Mice were then perfused with fluorescein isothiocyanate (FITC)-conjugated tomato (Lycopersicon esculentum) lectin to visualize the perfused cerebrovasculature. Short-day mice reduced hippocampal and cortical capillary density (FITC(+) area); vessels isolated from short day-exposed mice expressed higher mRNA levels of the gelatinase matrix metalloproteinase 2 (MMP2). Additionally, short-day mice reduced cerebral blood flow ∼15% compared with their long-day counterparts, as assessed by laser speckle flowmetry. Immunohistochemistry revealed higher levels of MMP2 in the hippocampus of mice maintained in short days compared with long days, potentially contributing to the observed vascular remodeling. These data demonstrate that a discrete environmental signal (i.e., day length) can substantially alter cerebral blood flow in adult mammals. PMID:27570829

  18. Cost and Effectiveness of Commercially Available Nesting Substrates for Deer Mice (Peromyscus maniculatus).

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    Martin, Tara L; Balser, Shannon R; Young, Gregory S; Lewis, Stephanie D

    2016-01-01

    Provision of nesting material promotes species-typical behaviors in rodents including deer mice (Peromyscus maniculatus). The purpose of this study was to determine which commercially available nesting material best promotes complex nest building in the subspecies P. m. bairdii yet remains cost-effective for use as enrichment in a laboratory research setting. An existing breeding colony consisting of cages containing all male mice, all female mice, and breeding pairs was evaluated. Five commercially available substrates-compressed cotton squares, cylindrical compressed cotton, cellulose bedding containing small pieces of evenly dispersed compressed paper, brown crinkled paper, and white crinkled paper-were provided according to the manufacturer's recommendation. Nests were evaluated at 24 h after cage change and scored for complexity. Nest complexity was compared between breeding pairs and single-sex cages and between male and female mice. Cages housing breeding pairs with pups had the highest average complexity score. The dispersed paper substrate was the least expensive substrate tested but had the lowest average nest complexity score. Nesting scores for brown crinkled paper, compressed cotton squares, and compressed cotton cylinders did not differ significantly despite the range in cost. Brown crinkled paper was the second least-expensive substrate tested, and mice used it to build consistently complex nests, making it the most practical substrate for use as enrichment for deer mice in a laboratory setting. PMID:27423147

  19. Associations Between Paternal Responsiveness and Stress Responsiveness in the Biparental California Mouse, Peromyscus californicus

    OpenAIRE

    Chauke, Miyetani

    2012-01-01

    The mechanistic basis of paternal behavior in mammals is poorly understood. Assuming there are parallels between the factors mediating maternal and paternal behavior, it can be expected that the onset of paternal behavior is facilitated by reductions in stress responsiveness, as occurs in females of several mammalian species. This dissertation describes studies investigating the role of stress responsiveness in the expression of paternal behavior in biparental, monogamous California mice (Per...

  20. Photoperiod mediated changes in olfactory bulb neurogenesis and olfactory behavior in male white-footed mice (Peromyscus leucopus.

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    James C Walton

    Full Text Available Brain plasticity, in relation to new adult mammalian neurons generated in the subgranular zone of the hippocampus, has been well described. However, the functional outcome of new adult olfactory neurons born in the subventricular zone of the lateral ventricles is not clearly defined, as manipulating neurogenesis through various methods has given inconsistent and conflicting results in lab mice. Several small rodent species, including Peromyscus leucopus, display seasonal (photoperiodic brain plasticity in brain volume, hippocampal function, and hippocampus-dependent behaviors; plasticity in the olfactory system of photoperiodic rodents remains largely uninvestigated. We exposed adult male P. leucopus to long day lengths (LD and short day lengths (SD for 10 to 15 weeks and then examined olfactory bulb cell proliferation and survival using the thymidine analog BrdU, olfactory bulb granule cell morphology using Golgi-Cox staining, and behavioral investigation of same-sex conspecific urine. SD mice did not differ from LD counterparts in granular cell morphology of the dendrites or in dendritic spine density. Although there were no differences due to photoperiod in habituation to water odor, SD mice rapidly habituated to male urine, whereas LD mice did not. In addition, short day induced changes in olfactory behavior were associated with increased neurogenesis in the caudal plexiform and granule cell layers of the olfactory bulb, an area known to preferentially respond to water-soluble odorants. Taken together, these data demonstrate that photoperiod, without altering olfactory bulb neuronal morphology, alters olfactory bulb neurogenesis and olfactory behavior in Peromyscus leucopus.

  1. Effects of reproductive status on behavioral and endocrine responses to acute stress in a biparental rodent, the California mouse (Peromyscus californicus)

    OpenAIRE

    Chauke, Miyetani; Malisch, Jessica L.; Robinson, Cymphonee; de Jong, Trynke R.; Saltzman, Wendy

    2011-01-01

    In several mammalian species, lactating females show blunted neural, hormonal, and behavioral responses to stressors. It is not known whether new fathers also show stress hyporesponsiveness in species in which males provide infant care. To test this possibility, we determined the effects of male and female reproductive status on stress responsiveness in the biparental, monogamous California mouse (Peromyscus californicus).Breeding (N=8 females, 8 males), nonbreeding (N=10 females, 10 males) a...

  2. Photoperiod interacts with food restriction on performance in the Barnes maze in female California mice

    OpenAIRE

    Steinman, Michael Q.; Crean, Katie K.; Trainor, Brian C.

    2010-01-01

    Food restriction has been reported to have positive effects on cognition. This study examines how another environmental factor, daylength, can alter the impact of food restriction on the brain and behavior. Female California mice (Peromyscus californicus), housed on either long days (16L:8D) or short days (8L:16D) were restricted to 80% of their normal baseline food intake or provided food ad libitum. Testing in a Barnes maze revealed that the effects of food restriction depend on photoperiod...

  3. Potential role of masting by introduced bamboos in deer mice (Peromyscus maniculatus population irruptions holds public health consequences.

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    Melissa C Smith

    Full Text Available We hypothesized that the ongoing naturalization of frost/shade tolerant Asian bamboos in North America could cause environmental consequences involving introduced bamboos, native rodents and ultimately humans. More specifically, we asked whether the eventual masting by an abundant leptomorphic ("running" bamboo within Pacific Northwest coniferous forests could produce a temporary surfeit of food capable of driving a population irruption of a common native seed predator, the deer mouse (Peromyscus maniculatus, a hantavirus carrier. Single-choice and cafeteria-style feeding trials were conducted for deer mice with seeds of two bamboo species (Bambusa distegia and Yushania brevipaniculata, wheat, Pinus ponderosa, and native mixed diets compared to rodent laboratory feed. Adult deer mice consumed bamboo seeds as readily as they consumed native seeds. In the cafeteria-style feeding trials, Y. brevipaniculata seeds were consumed at the same rate as native seeds but more frequently than wheat seeds or rodent laboratory feed. Females produced a median litter of 4 pups on a bamboo diet. Given the ability of deer mice to reproduce frequently whenever food is abundant, we employed our feeding trial results in a modified Rosenzweig-MacArthur consumer-resource model to project the population-level response of deer mice to a suddenly available/rapidly depleted supply of bamboo seeds. The simulations predict rodent population irruptions and declines similar to reported cycles involving Asian and South American rodents but unprecedented in deer mice. Following depletion of a mast seed supply, the incidence of Sin Nombre Virus (SNV transmission to humans could subsequently rise with dispersal of the peridomestic deer mice into nearby human settlements seeking food.

  4. Heavy metal exposure, reproductive activity, and demographic patterns in white-footed mice (Peromyscus leucopus) inhabiting a contaminated floodplain wetland

    International Nuclear Information System (INIS)

    We examined the concentrations of selected metals and selenium (Se) in the tissues of white-footed mice (Peromyscus leucopus) collected at a constructed wetland originally created as a retention basin for sediments dredged from Lake DePue, Illinois. These sediments were contaminated with high concentrations of cadmium (Cd), zinc (Zn), and other elements as a result of nearby smelting operations. White-footed mice inhabiting the former retention basin experienced greater exposure to Cd, Pb, and Se than those from nearby reference sites. Concentrations of Cu and Zn in livers of mice from the contaminated wetland and adjacent floodplain reference site were greater than in mice from the more-distant reference sites. Judging by concentrations in their kidneys, white-footed mice inhabiting the floodplain adjacent to the contaminated wetland had greater exposure to Cd than those from the two more-distant reference sites. Concentrations of Hg in tissues of mice did not vary appreciably among sites. Concentrations of Cd and Se in the tissues of some white-footed mice from the contaminated wetland exceeded critical concentrations observed in experimental studies of laboratory mice and rats; with few exceptions tissue Pb concentrations were below published effects levels. However, we did not detect changes in abundance, demographics, or reproductive activity that might suggest population-level effects of contaminant exposure. Mean weight of embryos expressed as a function of crown-rump length did not differ among locations sampled, and no gross lesions indicative of exposure to heavy metals were observed. Kidney and liver weight, corrected for body weight, were nominally, though not significantly, lowest in both male and female mice from areas of increased Cd and Pb exposure. Metals dredged from Lake DePue were still bioavailable 25 years after deposition. However, small mammal populations are resilient to environmental stressors and we did not detect differences in

  5. Acute effects of corticosterone injection on paternal behavior in California mouse (Peromyscus californicus) fathers.

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    Harris, Breanna N; Perea-Rodriguez, Juan Pablo; Saltzman, Wendy

    2011-11-01

    Glucocorticoids are thought to mediate the disruption of parental behavior in response to acute and chronic stress. Previous research supports their role in chronic stress; however, no study has experimentally tested the effects of acute glucocorticoid elevation on paternal behavior. We tested the prediction that acute corticosterone (CORT) increases would decrease paternal behavior in California mouse fathers and would lead to longer-term effects on reproductive success, as even short-term increases in CORT have been shown to produce lasting effects on the hypothalamic-pituitary-adrenal axis. First-time fathers were injected with 30 mg/kg CORT, 60 mg/kg CORT or vehicle, or left unmanipulated. Interactions between the male and its pup(s) were recorded 1.5-2h after injection and scored for paternal and non-paternal behavior. Treatment groups were combined into control (unmanipulated + vehicle, n = 15) and CORT (30 mg/kg + 60 mg/kg, n = 16) for analysis based on resulting plasma CORT concentrations. CORT treatment did not alter paternal or non-paternal behaviors or any long-term measures (male body mass or temperature, pup growth rate, pup survival, interbirth interval, number or mass of pups born in the second litter). Fathers showed a significant rise in body mass at day 30 postpartum, followed by a decrease in body mass after the birth of the second litter; however, this pattern did not differ between the CORT and control groups. In summary, acute elevation of plasma CORT did not alter direct paternal behavior, body mass, or reproductive outcomes, suggesting that acute CORT elevation alone does not overtly disrupt paternal care in this biparental mammal. PMID:21939660

  6. Peromyscus as a Mammalian Epigenetic Model

    Directory of Open Access Journals (Sweden)

    Kimberly R. Shorter

    2012-01-01

    Full Text Available Deer mice (Peromyscus offer an opportunity for studying the effects of natural genetic/epigenetic variation with several advantages over other mammalian models. These advantages include the ability to study natural genetic variation and behaviors not present in other models. Moreover, their life histories in diverse habitats are well studied. Peromyscus resources include genome sequencing in progress, a nascent genetic map, and >90,000 ESTs. Here we review epigenetic studies and relevant areas of research involving Peromyscus models. These include differences in epigenetic control between species and substance effects on behavior. We also present new data on the epigenetic effects of diet on coat-color using a Peromyscus model of agouti overexpression. We suggest that in terms of tying natural genetic variants with environmental effects in producing specific epigenetic effects, Peromyscus models have a great potential.

  7. Energetic cost of dietary exposure to polychlorinated biphenyls (PCBS) for white-footed mice, Peromyscus leucopus

    Science.gov (United States)

    Voltura, M.B.; French, J.B.

    1998-01-01

    Contaminant exposure is an environmental factor often overlooked in ecological studies. Yet exposure to toxicants is likely to be metabolically expensive, and result in a trade-off between energy spent to detoxify an excrete contaminants, and energy allocated to growth or reproduction. To quantify the energetic cost of PCB exposure, we fed mice diets containing 0, 0.1, 10 and 25 ppm PCBs (mg PCBs/kg food). After 6 wks, there were no differences in food intake or body mass related to the level of dietary PCBs. We continued to feed mice the PCB diets for one year, and then measured food intake and resting metabolic rate. After one year, all mice had gained mass, but mice on the 25 ppm diet were significantly heavier than mice in the other groups. Mice on the 25 ppm diet also showed an increase in both food intake (p=0.06) and metabolic rate (p=0.01), after correction for differences in body mass. Food intake averaged 4.1 g/d for mice on the 25 ppm diet, compared to 3.7 gld for control mice. Oxygen consumption at 30°C averaged 40.1 ml O2/h for mice on the 25 ppm diet, compared to 36.6 ml O2/h for control mice. These results show that for white-footed mice, there is an energetic cost to contaminant exposure that when combined with other environmental stresses, will influence patterns of energy acquisition and allocation.

  8. Evolution of Peromyscus leucopus mice in response to a captive environment.

    Directory of Open Access Journals (Sweden)

    Robert C Lacy

    Full Text Available Many wildlife species are propagated in captivity as models for behavioral, physiological, and genetic research or to provide assurance populations to protect threatened species. However, very little is known about how animals evolve in the novel environment of captivity. The histories of most laboratory strains are poorly documented, and protected populations of wildlife species are usually too small and too short-term to allow robust statistical analysis. To document the evolutionary change in captive breeding programs, we monitored reproduction and behavior across 18 generations in six experimental populations of Peromyscusleucopus mice started from a common set of 20 wild-caught founders. The mice were propagated under three breeding protocols: a strategy to retain maximal genetic diversity, artificial selection against stereotypic behaviors that were hypothesized to reflect poor adaptation to captivity, and random bred controls. Two replicates were maintained with each protocol, and inter-replicate crosses at generations 19 and 20 were used to reverse accumulated inbreeding. We found that one of the stereotypic behaviors (repetitive flipping was positively associated with reproductive fitness, while the other (gnawing was relatively invariant. Selection to reduce these stereotypic behaviors caused marked reduction in reproduction, and populations not under artificial selection to reduce these behaviors responded with large increases in flipping. In non-selected populations, there was rapid evolution toward much higher proportion of pairs breeding and more rapid conception. Litter size, pup survival, and weaning mass all declined slowly, to the extent that would be predicted based on inbreeding depression. Inter-crossing between replicate populations reversed these declines in fitness components but did not reverse the changes in behavior or the accelerated breeding. These findings indicate that adaptation to captivity can be rapid

  9. Spatial Navigation Strategies in Peromyscus: a Comparative Study.

    Science.gov (United States)

    Jašarević, Eldin; Williams, Scott A; Roberts, R Michael; Geary, David C; Rosenfeld, Cheryl S

    2012-11-01

    A male advantage in spatial abilities is predicted to evolve in species where males rely on expansion of home territory to locate dispersed mates during the breeding season. We sought to examine mechanistic underpinnings of this evolved trait by comparing spatial navigational abilities in two species of Peromyscus that employ widely different reproductive strategies. Males and females from outbred stocks of deer mice (P. maniculatus bairdii) in which males engage in territorial expansion and mate search and California mice (P. californicus insignis), in which males do not, were administered tasks that assessed spatial learning and memory, and activity and exploratory behaviours. The maze employed for these studies included four spatial cues that could be used to aid in locating 1 of 12 potential escape holes. As predicted, male deer mice outperformed conspecific females and California mice males in maze performance and memory, and this difference appeared to be due to extent to which animals used spatial cues to guide maze navigation. Consistent with territorial expansion as a component of competition for mates, male deer mice were more active and engaged in more exploratory and less anxiety-related behaviours than conspecific females and California mice males. The results have implications for understanding and studying the cognitive and behavioural mechanisms that have evolved through male-male competition that involves territorial expansion and mate search. PMID:23355748

  10. Hymenolepis folkertsi n. sp. (Eucestoda: Hymenolepididae) in the oldfield mouse Peromyscus polionotus from the southeastern Nearctic with comments on tapeworm faunal diversity among deer mice

    Science.gov (United States)

    A previously unrecognized species of hymenolepidid cestode attributable to Hymenolepis Weinland, 1858 is described based on specimens in Peromyscus polionotus, oldfield mouse, from Georgia near the southeastern coast of continental North America. Specimens of Hymenolepis folkertsi n. sp. differ from...

  11. Phenotypic Plasticity in the Lungs of Deer Mice (Peromyscus maniculatus) at High Altitude and the Relationship With Aerobic Performance

    OpenAIRE

    Shirkey, Nicholas Joseph

    2013-01-01

    The importance of phenotypic plasticity during post developmental acclimation to high altitude has been recognized in the recent years. However, the relationship between morphological changes observed in the lungs resulting from this acclimation process and changes in aerobic performance at high altitude have not been sufficiently investigated. This thesis attempts to elucidate the specific morphological changes associated with changes in the lungs of adult deer mice acclimated to high altitu...

  12. Spatial Navigation Strategies in Peromyscus: a Comparative Study

    OpenAIRE

    Jašarević, Eldin; Williams, Scott A.; Roberts, R Michael; Geary, David C.; Rosenfeld, Cheryl S.

    2012-01-01

    A male advantage in spatial abilities is predicted to evolve in species where males rely on expansion of home territory to locate dispersed mates during the breeding season. We sought to examine mechanistic underpinnings of this evolved trait by comparing spatial navigational abilities in two species of Peromyscus that employ widely different reproductive strategies. Males and females from outbred stocks of deer mice (P. maniculatus bairdii) in which males engage in territorial expansion and ...

  13. Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice.

    Science.gov (United States)

    Greenberg, Gian D; Steinman, Michael Q; Doig, Ian E; Hao, Rebecca; Trainor, Brian C

    2015-12-01

    Dopamine neurons in the ventral tegmental area (VTA) have important functions related to rewards but are also activated in aversive contexts. Electrophysiology studies suggest that the degree to which VTA dopamine neurons respond to noxious stimuli is topographically organized across the dorsal-ventral extent. We used c-fos immunohistochemistry to examine the responses of VTA dopamine neurons in contexts of social defeat and social approach. Studying monogamous California mice (Peromyscus californicus) allowed us to observe the effects of social defeat on both males and females. Females exposed to three episodes of defeat, but not a single episode, had more tyrosine hydroxylase (TH)/c-fos-positive cells in the ventral (but not dorsal) VTA compared with controls. This observation suggests that repeated exposure to aversive contexts is necessary to trigger activation of VTA dopamine neurons. Defeat did not affect TH/c-fos colocalizations in males. We also examined the long-term effects of defeat on c-fos expression in a social interaction test. As previously reported, defeat reduced social interaction in females but not males. Surprisingly, there were no effects of defeat stress on TH/c-fos colocalizations in any subregion of the VTA. However, females had more TH/c-fos-positive cells than males across the entire VTA, and also had greater c-fos-positive cell counts in posterior subregions of the nucleus accumbens shell. Our results show that dopamine neurons in the VTA are more responsive to social contexts in females and that the ventral VTA in particular is sensitive to aversive contexts. PMID:26469289

  14. Effects of Captivity on Response to a Novel Environment in the Oldfield Mouse (Peromyscus polionotus subgriseus)

    OpenAIRE

    McPhee, M. Elsbeth

    2003-01-01

    Long-term maintenance of captive populations and release of these animals into the wild is one approach to endangered species conservation. In this study, I used a traditional ethological technique, the open-field test, to assess captivity's effects on exploratory behavior, level of activity, and enclosure use in oldfield mice (Peromyscus polionotus subgriseus) upon introduction to a novel environment. The animals tested were from four populations collected from Ocala National Forest, Florida...

  15. A method to distinguish morphologically similar Peromyscus species using extracellular RNA and high-resolution melt analysis.

    Science.gov (United States)

    Seifert, Veronica A; Clarke, Benjamin L; Crossland, Janet P; Bemis, Lynne T

    2016-09-01

    A method applying high-resolution melt (HRM) analysis to PCR products copied and amplified from extracellular RNA (exRNA) has been developed to distinguish two morphologically similar Peromyscus species: Peromyscus leucopus and Peromyscus maniculatus. P. leucopus is considered the primary reservoir host of Borrelia burgdorferi, the causative agent for Lyme disease in North America. In northern Minnesota the habitat ranges of P. leucopus overlaps with that of P. maniculatus. Serum samples from live mice of both species were collected from cheek bleeds, total extracellular RNA (exRNA) was extracted, copied using reverse transcription and amplified by PCR followed by HRM analysis. A circulating ribosomal RNA (rRNA) was identified which differed at seven nucleotides between the two species and a method of HRM analysis was developed allowing rapid species confirmation. In the future, this HRM based method may be adapted for additional species. PMID:27349513

  16. PREDICTION OF PEROMYSCUS MANICULATUS (DEER MOUSE) POPULATION DYNAMICS IN MONTANA, USA, USING SATELLITE-DRIVEN VEGETATION PRODUCTIVITY AND WEATHER DATA

    OpenAIRE

    Loehman, Rachel A.; Elias, Joran; Douglass, Richard J.; Kuenzi, Amy J.; Mills, James N.; Wagoner, Kent

    2012-01-01

    Deer mice (Peromyscus maniculatus) are the main reservoir host for Sin Nombre virus, the primary etiologic agent of hantavirus pulmonary syndrome in North America. Sequential changes in weather and plant productivity (trophic cascades) have been noted as likely catalysts of deer mouse population irruptions, and monitoring and modeling of these phenomena may allow for development of early-warning systems for disease risk. Relationships among weather variables, satellite-derived vegetation prod...

  17. Pneumocystosis in wild small mammals from California

    Science.gov (United States)

    Laakkonen, J.; Fisher, R.N.; Case, T.J.

    2001-01-01

    Cyst forms of the opportunistic fungal parasite Pneumocystis carinii were found in the lungs of 34% of the desert shrew, Notiosorex crawfordi (n = 59), 13% of the ornate shrew, Sorex ornatus (n = 55), 6% of the dusky-footed wood rat, Neotoma fuscipes (n = 16), 2.5% of the California meadow vole, Microtus californicus (n = 40), and 50% of the California pocket mouse, Chaetodipus californicus (n = 2) caught from southern California between February 1998 and February 2000. Cysts were not found in any of the harvest mouse, Reithrodontomys megalotis (n = 21), California mouse, Peromyscus californicus (n = 20), brush mouse, Peromyscus boylii (n = 7) or deer mouse, Peromyscus maniculatus (n = 4) examined. All infections were mild; extrapulmonary infections were not observed. Other lung parasites detected were Hepatozoon sp./ spp. from M. californicus and Notiosorex crawfordi, Chrysosporium sp. (Emmonsia) from M. californicus, and a nematode from S. ornatus.

  18. Social, but not photoperiodic, influences on reproductive function in male Peromyscus aztecus.

    Science.gov (United States)

    Demas, G E; Nelson, R J

    1998-02-01

    Nontropical rodents rely on environmental factors to restrict breeding to a specific time of the year. Among these factors, photoperiod appears to be the primary environmental cue used for predicting optimal breeding conditions. The purpose of the present study was to characterize reproductive function, as well as photoperiodic and social responsiveness in male Peromyscus aztecus, which occupy low-latitude, high-altitude habitats. In experiment 1, adult male P. aztecus were individually housed in either long (16L:8D) or short days (8L:16D) for 10 wk. Short-day mice did not differ from long-day mice on any reproductive or nonreproductive parameter. Comparisons to related Peromyscus species suggested that relative reproductive organ size and function were reduced in both long- and short-day males. Because ad libitum food and water were available, we reasoned that males in both photoperiodic conditions lacked social stimuli. To test this hypothesis, adult male P. aztecus were housed in long days either individually or with a female conspecific in experiment 2. Mice housed with females had significantly larger relative paired testes and epididymal masses, and higher testicular sperm counts and serum testosterone levels compared to those of individually housed mice. Taken together, these results suggest that social factors may play a more prominent role than photoperiod in stimulating reproductive development in laboratory-housed P. aztecus. These results are consistent with the results found for other low-latitude rodent species and suggest that P. aztecus uses a flexible rather than obligatory breeding strategy. PMID:9475393

  19. Effects of dietary PCB exposure on reproduction in the white-footed mouse (Peromyscus leucopus)

    Science.gov (United States)

    Voltura, M.B.; French, J.B.

    2007-01-01

    Studies of the impact of environmental contaminants on reproduction have typically focused on effects on fertility and subsequent reproductive failure. Contaminants may also impact reproductive output or other aspects of life history through effects on resource acquisition or allocation. We fed successfully breeding female white-footed mice (Peromyscus leucopus) diets containing polychlorinated biphenyls (2:1 Aroclor 1242:1254) at levels of 0 (n = 10), 10 (n = 12), and 25 (n = 10) ppm (mg polychlorinated biphenyls [PCBs]/kg food). After 4 months on the diets, female mice were bred with male mice maintained on control food. There was no effect of PCB exposure on litter size at birth or weaning, although fewer female mice on the 25-ppm diet gave birth. There was no effect of PCB dose on maternal metabolic rate at peak lactation or on total food (dry matter) intake during lactation. Female mice on the 10-ppm diet, however, consumed more food per pup during lactation and weaned larger pups, although these differences disappeared after 4 weeks of age. We conclude that although moderate-term exposure to PCBs did decrease the number of litters produced for high-dose female mice, it did not change litter size, pup growth rate, or energetic measures for those female mice that did successfully reproduce.

  20. Molecular linkage of hantavirus pulmonary syndrome to the white-footed mouse, Peromyscus leucopus: genetic characterization of the M genome of New York virus.

    OpenAIRE

    Hjelle, B; Lee, S. W.; Song, W.; Torrez-Martinez, N; Song, J. W.; Yanagihara, R; Gavrilovskaya, I; Mackow, E R

    1995-01-01

    The complete M segment sequences of hantaviruses amplified from tissues of a patient with hantavirus pulmonary syndrome in the northeastern United States and from white-footed mice, Peromyscus leucopus, from New York were 99% identical and differed from those of Four Corners virus by 23%. The serum of this patient failed to recognize a conserved, immunodominant epitope of the Four Corners virus G1 glycoprotein. Collectively, these findings indicate that P. leucopus harbors a genetically and a...

  1. Generation of competent bone marrow-derived antigen presenting cells from the deer mouse (Peromyscus maniculatus

    Directory of Open Access Journals (Sweden)

    Farrell Regina M

    2004-09-01

    Full Text Available Abstract Background Human infections with Sin Nombre virus (SNV and related New World hantaviruses often lead to hantavirus cardiopulmonary syndrome (HCPS, a sometimes fatal illness. Lungs of patients who die from HCPS exhibit cytokine-producing mononuclear infiltrates and pronounced pulmonary inflammation. Deer mice (Peromyscus maniculatus are the principal natural hosts of SNV, in which the virus establishes life-long persistence without conspicuous pathology. Little is known about the mechanisms SNV employs to evade the immune response of deer mice, and experimental examination of this question has been difficult because of a lack of methodologies for examining such responses during infection. One such deficiency is our inability to characterize T cell responses because susceptible syngeneic deer mice are not available. Results To solve this problem, we have developed an in vitro method of expanding and generating competent antigen presenting cells (APC from deer mouse bone marrow using commercially-available house mouse (Mus musculus granulocyte-macrophage colony stimulating factor. These cells are capable of processing and presenting soluble protein to antigen-specific autologous helper T cells in vitro. Inclusion of antigen-specific deer mouse antibody augments T cell stimulation, presumably through Fc receptor-mediated endocytosis. Conclusions The use of these APC has allowed us to dramatically expand deer mouse helper T cells in culture and should permit extensive characterization of T cell epitopes. Considering the evolutionary divergence between deer mice and house mice, it is probable that this method will be useful to other investigators using unconventional models of rodent-borne diseases.

  2. Final Critical Habitat for the Alabama Beach Mouse (Peromyscus polionotus ammobates)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — These data identify, in general, the areas where final critical habitat for the Alabama Beach Mouse (Peromyscus polionotus ammobates) occur.

  3. Urbanization shapes the demographic history of a native rodent (the white-footed mouse, Peromyscus leucopus) in New York City.

    Science.gov (United States)

    Harris, Stephen E; Xue, Alexander T; Alvarado-Serrano, Diego; Boehm, Joel T; Joseph, Tyler; Hickerson, Michael J; Munshi-South, Jason

    2016-04-01

    How urbanization shapes population genomic diversity and evolution of urban wildlife is largely unexplored. We investigated the impact of urbanization on white-footed mice,Peromyscus leucopus,in the New York City (NYC) metropolitan area using coalescent-based simulations to infer demographic history from the site-frequency spectrum. We assigned individuals to evolutionary clusters and then inferred recent divergence times, population size changes and migration using genome-wide single nucleotide polymorphisms genotyped in 23 populations sampled along an urban-to-rural gradient. Both prehistoric climatic events and recent urbanization impacted these populations. Our modelling indicates that post-glacial sea-level rise led to isolation of mainland and Long Island populations. These models also indicate that several urban parks represent recently isolated P. leucopus populations, and the estimated divergence times for these populations are consistent with the history of urbanization in NYC. PMID:27072402

  4. Distribution of Borrelia burgdorferi in host mice in Pennsylvania.

    OpenAIRE

    Lord, R D; Lord, V R; Humphreys, J. G.; McLean, R G

    1994-01-01

    Host mice (Peromyscus leucopus and Peromyscus maniculatus) were sampled throughout the state of Pennsylvania to determine the geographical and ecological distribution of the Lyme disease spirochete Borrelia burgdorferi. All 67 counties of the state were sampled. A total of 1,619 mice were captured from a total of 157 sites during the period 1990 to 1993 for an overall capture rate of 29.69%. A total of 112 (6.92%) isolations of B. burgdorferi were made. The distribution of isolations revealed...

  5. Intercropping switchgrass with loblolly pine does not influence the functional role of the white-footed mouse (Peromyscus leucopus)

    International Nuclear Information System (INIS)

    Intercropping biofuel feedstocks in managed forests of the southeastern United States is a potentially sustainable source of renewable energy. Ecological effects of energy crops in forests are poorly understood, and it is unknown whether the ecological role of native rodents is influenced by alternative food resources. Therefore, we used a stable isotope analysis to compare diet and trophic responses of white-footed mice (Peromyscus leucopus) in 1) plots where switchgrass (Panicum virgatum), a C4 plant, was intercropped with loblolly pine (Pinus taeda), a C3 plant, 2) plots of loblolly pine, and 3) plots of monocropped switchgrass. We collected fur from live-trapped rodents and potential dietary sources in 2010. We predicted δ13C and δ15N values of mice in switchgrass plots would reflect a C4-based, granivorous, diet if there was an effect of intercropping on the functional role of mice. Del13C values of mouse fur in monocropped switchgrass, but not intercropped switchgrass plots, shifted more toward a C4 signal. However, δ15N values indicated that mice remained functionally omnivorous across treatments. Our results were supported by isotope values from invertebrates across guilds. Diet and trophic position of white-footed mice was not influenced by intercropping switchgrass in pine plantations indicating they maintained their functional role in this biofuels management regime. Future research should focus on individual and population responses of rodents to altered vegetation structure where biofuels feedstocks are grown and indirect effects on inter- and intra-species interactions. -- Highlights: •We examined carbon source and trophic position of mice in pine × switchgrass intercropped forests. •The δ13C values of mice in intercropped plots did not differ from control plots. •The δ15N values of mice in intercropped plots did not differ among treatment plots. •Plant and invertebrate δ13C and δ15N values were as expected, and supported our mouse

  6. REPRODUCTIVE DEVELOPMENT IN MALE DEER MICE EXPOSED TO AGGRESSIVE BEHAVIOR

    Science.gov (United States)

    Male deer mice (Peromyscus maniculatus bairdii) were reared in a long photoperiod and housed individually from 3 weeks of age until they were killed 2, 4, or 6 weeks later. Males that were exposed to aggressive females for 2 min, three times per week, were of normal body weight a...

  7. Phenotypic Plasticity of the Lung Surfactant System at High Altitude in Deer Mice, Peromyscus maniculatus

    OpenAIRE

    Diaz, Sonia

    2012-01-01

    The pulmonary surfactant system is a multifaceted and highly complex mixture of lipids and proteins that work to reduce the surface tension created at the air-liquid interface within the lung, and provide innate immunity to the lung. Reducing surface tension allows for lung stability, patency and functioning, a crucial task to undertake in oxygen-limiting environments, such as high altitude. The lower partial pressures of oxygen and colder ambient temperatures found at high altitude pose a ...

  8. SERUM ANTIBODIES TO BORRELIA BURGDORFERI, ANAPLASMA PHAGOCYTOPHILUM, AND BABESIA MICROTI IN RECAPTURED WHITE-FOOTED MICE

    OpenAIRE

    Magnarelli, Louis A.; Williams, Scott C.; Norris, Steven J; Fikrig, Erol

    2013-01-01

    A mark-release-recapture study was conducted during 2007 through 2010 in six, tick-infested sites in Connecticut, United States to measure changes in antibody titers for Borrelia burgdorferi sensu stricto, Anaplasma phagocytophilum, and Babesia microti in Peromyscus leucopus (white-footed mice). There was an overall recapture rate of 40%, but only four tagged mice were caught in ≥2 yr. Sera from 561 mice were analyzed for total antibodies to B. burgdorferi and A. phagocytophilum by using whol...

  9. Pilot Inventory of Mammals, Reptiles, and Amphibians, Golden Gate National Recreation Area, California, 1990-1997

    Science.gov (United States)

    Semenoff-Irving, Marcia; Howell, Judd A.

    2005-01-01

    The United States Geological Survey Golden Gate Field Station conducted a baseline inventory of terrestrial vertebrates within the Golden Gate National Recreation Area (GGNRA), Marin, San Francisco, and San Mateo Counties, California between 1990 and 1997. We established 456 permanent study plots in 6 major park habitats, including grassland, coastal scrub, riparian woodland, coastal wetland, broad-leaved evergreen forest, and needle-leaved evergreen forest. We tested multiple inventory methods, including live traps, track plate stations, and artificial cover boards, across all years and habitats. In most years, sampling occurred in 3-4 primary sampling sessions between July and September. In 1994, additional sampling occurred in February and May in conjunction with an assessment of Hantavirus exposure in deer mice (Peromyscus maniculatus). Overall, we detected 32 mammal, 14 reptile, and 6 amphibian species during 25,222 trap-nights of effort. The deer mouse-the most abundant species detected--accounted for 67% of total captures. We detected the Federal Endangered salt marsh harvest mouse (Reithrodontomys raviventris) at one coastal wetland plot in 1992. This project represents the first phase in the development of a comprehensive terrestrial vertebrate inventory and monitoring program for GGNRA. This report summarizes data on relative abundance, frequency of occurrence, distribution across habitat types, and trap success for terrestrial vertebrates detected during this 7-year effort. It includes comprehensive descriptions of the inventory methods and sampling strategies employed during this survey and is intended to help guide the park in the implementation of future longterm ecological monitoring programs.

  10. Urban park characteristics, genetic variation, and historical demography of white-footed mouse (Peromyscus leucopus populations in New York City

    Directory of Open Access Journals (Sweden)

    Jason Munshi-South

    2014-03-01

    Full Text Available Severe fragmentation is a typical fate of native remnant habitats in cities, and urban wildlife with limited dispersal ability are predicted to lose genetic variation in isolated urban patches. However, little information exists on the characteristics of urban green spaces required to conserve genetic variation. In this study, we examine whether isolation in New York City (NYC parks results in genetic bottlenecks in white-footed mice (Peromyscus leucopus, and test the hypotheses that park size and time since isolation are associated with genetic variability using nonlinear regression and information-theoretic model selection. White-footed mice have previously been documented to exhibit male-biased dispersal, which may create disparities in genetic variation between males and females in urban parks. We use genotypes of 18 neutral microsatellite data and four different statistical tests to assess this prediction. Given that sex-biased dispersal may create disparities between population genetic patterns inferred from bi- vs. uni-parentally inherited markers, we also sequenced a 324 bp segment of the mitochondrial D-loop for independent inferences of historical demography in urban P. leucopus. We report that isolation in urban parks does not necessarily result in genetic bottlenecks; only three out of 14 populations in NYC parks exhibited a signature of a recent bottleneck at 18 neutral microsatellite loci. Mouse populations in larger urban parks, or parks that have been isolated for shorter periods of time, also do not generally contain greater genetic variation than populations in smaller parks. These results suggest that even small networks of green spaces may be sufficient to maintain the evolutionary potential of native species with certain characteristics. We also found that isolation in urban parks results in weak to nonexistent sex-biased dispersal in a species known to exhibit male-biased dispersal in less fragmented environments. In

  11. A comparison of scent marking between a monogamous and promiscuous species of peromyscus: pair bonded males do not advertise to novel females.

    Directory of Open Access Journals (Sweden)

    Elizabeth A Becker

    Full Text Available Scent marking can provide behavioral and physiological information including territory ownership and mate advertisement. It is unknown how mating status and pair cohabitation influence marking by males from different social systems. We compared the highly territorial and monogamous California mouse (Peromyscus californicus to the less territorial and promiscuous white-footed mouse (P. leucopus. Single and mated males of both species were assigned to one of the following arenas lined with filter paper: control (unscented arena, male scented (previously scent-marked by a male conspecific, or females present (containing females in small cages. As expected, the territorial P. californicus scent marked and overmarked an unfamiliar male conspecific's scent marks more frequently than P. leucopus. Species differences in responses to novel females were also found based on mating status. The presence of unfamiliar females failed to induce changes in scent marking in pair bonded P. californicus even though virgin males increased marking behavior. Pair bonding appears to reduce male advertisement for novel females. This is in contrast to P. leucopus males that continue to advertise regardless of mating status. Our data suggest that communication through scent-marking can diverge significantly between species based on mating system and that there are physiological mechanisms that can inhibit responsiveness of males to female cues.

  12. Effects of Parental Status on Male Body Mass in the Monogamous, Biparental California Mouse

    OpenAIRE

    Saltzman, W; Harris, BN; De Jong, TR; Nguyen, PP; Cho, JT; HERNANDEZ, M; Perea-Rodriguez, JP

    2015-01-01

    © 2015 The Zoological Society of London. Studies of biparental mammals demonstrate that males may undergo systematic changes in body mass as a consequence of changes in reproductive status; however, these studies typically have not teased apart the effects of specific social and reproductive factors, such as cohabitation with a female per se, cohabitation with a breeding female specifically, and engagement in paternal care. We aimed to determine whether California mouse Peromyscus californicu...

  13. Influence of stimuli from populations of Peromyscus leucopus on maturation of young

    Science.gov (United States)

    Rogers, J.G., Jr.; Beauchamp, G.K.

    1976-01-01

    The effects of stimuli associated with conspecific laboratory populations on parameters of sexual maturation in Peromyscus leucopus were examined. Beginning at birth, experimental litters were exposed to the constant infusion of urine, feces, and other material from the populations through a metabolism funnel into their cages. As evidenced by age at first vaginal estrus, experimental females matured later than controls. They also had lighter weight reproductive organs. Testis weights were much greater in control than experimental males. These data suggest that stimuli from populations of P. leucopus can inhibit reproductive maturation of conspecifics. In view of the well-documented effects of chemical stimuli on reproductive maturation and function in other rodents, it is suggested that chemical stimuli in the feces, urine, or from other sources mediated the reproductive inhibition observed in this study.

  14. Intra- and interindividual variations mask interspecies variation in the microbiota of sympatric peromyscus populations.

    Science.gov (United States)

    Baxter, Nielson T; Wan, Judy J; Schubert, Alyxandria M; Jenior, Matthew L; Myers, Philip; Schloss, Patrick D

    2015-01-01

    Using populations of two sympatric Peromyscus species, we characterized the importance of the host species, physiology, environment, diet, and other factors in shaping the structure and dynamics of their gut microbiota. We performed a capture-mark-release experiment in which we obtained 16S rRNA gene sequence data from 49 animals at multiple time points. In addition, we performed 18S rRNA gene sequencing of the same samples to characterize the diet of each individual. Our analysis could not distinguish between the two species of Peromyscus on the basis of the structures of their microbiotas. However, we did observe a set of bacterial populations that were found in every animal. Most notable were abundant representatives of the genera Lactobacillus and Helicobacter. When we combined the 16S and 18S rRNA gene sequence analyses, we were unable to distinguish the communities on the basis of the animal's diet. Furthermore, there were no discernible differences in the structure of the gut communities based on the capture site or their developmental or physiological status. Finally, in contrast to humans, where each individual has a unique microbiota when sampled over years, among the animals captured in this study, the uniqueness of each microbiota was lost within a week of the original sampling. Wild populations provide an opportunity to study host-microbiota interactions as they originally evolved, and the ability to perform natural experiments will facilitate a greater understanding of the factors that shape the structure and function of the gut microbiota. PMID:25362056

  15. Differential Lymphocyte and Antibody Responses in Deer Mice Infected with Sin Nombre Hantavirus or Andes Hantavirus

    OpenAIRE

    Schountz, Tony; Quackenbush, Sandra; Rovnak, Joel; Haddock, Elaine; Black, William C.; Feldmann, Heinz; Prescott, Joseph

    2014-01-01

    Hantavirus cardiopulmonary syndrome (HCPS) is a rodent-borne disease with a high case-fatality rate that is caused by several New World hantaviruses. Each pathogenic hantavirus is naturally hosted by a principal rodent species without conspicuous disease and infection is persistent, perhaps for life. Deer mice (Peromyscus maniculatus) are the natural reservoirs of Sin Nombre virus (SNV), the etiologic agent of most HCPS cases in North America. Deer mice remain infected despite a helper T cell...

  16. Nitric oxide production by Peromyscus yucatanicus (Rodentia infected with Leishmania (Leishmania mexicana

    Directory of Open Access Journals (Sweden)

    Elsy Nalleli Loría-Cervera

    2013-04-01

    Full Text Available Peromyscus yucatanicus (Rodentia: Cricetidae is a primary reservoir of Leishmania (Leishmania mexicana (Kinetoplastida: Trypanosomatidae. Nitric oxide (NO generally plays a crucial role in the containment and elimination of Leishmania. The aim of this study was to determine the amount of NO produced by P. yucatanicus infected with L. (L. mexicana. Subclinical and clinical infections were established in P. yucatanicus through inoculation with 1 x 10 2 and 2.5 x 10 6 promastigotes, respectively. Peritoneal macrophages were cultured alone or co-cultured with lymphocytes with or without soluble Leishmania antigen. The level of NO production was determined using the Griess reaction. The amount of NO produced was significantly higher (p ≤ 0.0001 in co-cultured macrophages and lymphocytes than in macrophages cultured alone. No differences in NO production were found between P. yucatanicus with subclinical L. (L. mexicana infections and animals with clinical infections. These results support the hypothesis that the immunological mechanisms of NO production in P. yucatanicus are similar to those described in mouse models of leishmaniasis and, despite NO production, P. yucatanicus is unable to clear the parasite infection.

  17. Efectos de la contaminación atmosférica en poblaciones de pequeños roedores silvestres ("Microtus mexicanus", "Peromyscus melanotis" y "Peromyscus difficilis") en México, D. F.

    OpenAIRE

    Gómez Ugalde, Rosa María

    2003-01-01

    [spa] El objetivo del presente trabajo es evaluar la influencia de la contaminación atmosférica de la Zona Metropolitana de la Ciudad de México sobre las poblaciones de Microtus mexicanus, Peromyscus melanosis y P. difficilis en los Parques Nacionales: Desiertode los Leones (Desierto) y el Ajusco (Ajusco) para lo cual se analizó la estructura y ultraestructura del epitelio traqueal; el análisis histopatológico de: pulmón, hígado, bazo y riñón y la acumulación de metales (As, Al, Cd, Cr, Cu, M...

  18. Sex Differences in Social Interaction Behavior Following Social Defeat Stress in the Monogamous California Mouse (Peromyscus californicus)

    OpenAIRE

    Trainor, Brian C.; Pride, Michael C.; Rosalina Villalon Landeros; Knoblauch, Nicholas W; Takahashi, Elizabeth Y.; Andrea L Silva; Crean, Katie K.

    2011-01-01

    Stressful life experiences are known to be a precipitating factor for many mental disorders. The social defeat model induces behavioral responses in rodents (e.g. reduced social interaction) that are similar to behavioral patterns associated with mood disorders. The model has contributed to the discovery of novel mechanisms regulating behavioral responses to stress, but its utility has been largely limited to males. This is disadvantageous because most mood disorders have a higher incidence i...

  19. Non-alcohol dehydrogenase-mediated metabolism of methylazoxymethanol in the deer mouse, Peromyscus maniculatus

    International Nuclear Information System (INIS)

    The concept that alcohol dehydrogenase (ADH) is involved in the metabolism of methylazoxymethanol (MAM) was examined in a model consisting of two strains of the deer mouse, Peromyscus maniculatus, one of which has a normal complement of the enzyme [ADH(+)], and the other, which completely lacks it [ADH(-)]. Both the ADH(+) and the ADH(-) strains rapidly metabolized [14C]MAM, administered in the form of the acetic acid ester, [14C] MAMOAc, to 14CO2, and the rates and extents of metabolism were virtually identical. Determination of O6-methylguanine and 7-methylguanine in liver DNA 6 and 24 hr after MAMOAc (25 mg/kg) administration showed that the levels of DNA methylation induced by the carcinogen were not significantly different in the two strains, indicating that both are capable of the metabolic activation of MAM to methylating species. Pyrazole, a potent inhibitor of ADH, inhibited MAM metabolism as well as liver DNA methylation in the ADH(+) strain; however similar inhibition of these processes also occurred in the ADH(-) strain. 3-Methylpyrazole, a weak or noninhibitor of ADH, also decreased the levels of MAM metabolism in both the ADH(+) and the ADH(-) strains. From these results, the authors conclude that ADH is not obligatory either in the metabolism or in the metabolic activation of MAM. As a possible alternative to ADH, liver microsomes were examined for their ability to metabolize MAM. In the presence of a NADPH-generating system, liver microsomes from both strains converted [14C]MAM to 14CH3OH and 14CH2O, although liver microsomes from the ADH(-) strain were more active in this respect. The microsomal metabolism was sensitive to inhibition by CO as well as to inhibition by pyrazole and 3-methylpyrazole

  20. Competition drives cooperation among closely-related sperm of deer mice

    OpenAIRE

    FISHER, HEIDI S.; Hoekstra, Hopi E.

    2010-01-01

    Among the extraordinary adaptations driven by sperm competition is the cooperative behaviour of spermatozoa1. By forming cooperative groups, sperm can increase their swimming velocity and thereby gain an advantage in intermale sperm competition1,2. Accordingly, selection should favour cooperation of the most closely related sperm to maximize fitness3. Here we show that sperm of deer mice (genus Peromyscus) form motile aggregations, then we use this system test predictions of sperm cooperation...

  1. California Bioregions

    Data.gov (United States)

    California Department of Resources — California regions developed by the Inter-agency Natural Areas Coordinating Committee (INACC) were digitized from a 1:1,200,000 California Department of Fish and...

  2. Urban landscape genetics: canopy cover predicts gene flow between white-footed mouse (Peromyscus leucopus) populations in New York City.

    Science.gov (United States)

    Munshi-South, Jason

    2012-03-01

    In this study, I examine the influence of urban canopy cover on gene flow between 15 white-footed mouse (Peromyscus leucopus) populations in New York City parklands. Parks in the urban core are often highly fragmented, leading to rapid genetic differentiation of relatively nonvagile species. However, a diverse array of 'green' spaces may provide dispersal corridors through 'grey' urban infrastructure. I identify urban landscape features that promote genetic connectivity in an urban environment and compare the success of two different landscape connectivity approaches at explaining gene flow. Gene flow was associated with 'effective distances' between populations that were calculated based on per cent tree canopy cover using two different approaches: (i) isolation by effective distance (IED) that calculates the single best pathway to minimize passage through high-resistance (i.e. low canopy cover) areas, and (ii) isolation by resistance (IBR), an implementation of circuit theory that identifies all low-resistance paths through the landscape. IBR, but not IED, models were significantly associated with three measures of gene flow (Nm from F(ST) , BayesAss+ and Migrate-n) after factoring out the influence of isolation by distance using partial Mantel tests. Predicted corridors for gene flow between city parks were largely narrow, linear parklands or vegetated spaces that are not managed for wildlife, such as cemeteries and roadway medians. These results have implications for understanding the impacts of urbanization trends on native wildlife, as well as for urban reforestation efforts that aim to improve urban ecosystem processes. PMID:22320856

  3. Poleward expansion of the white-footed mouse (Peromyscus leucopus under climate change: implications for the spread of lyme disease.

    Directory of Open Access Journals (Sweden)

    Emilie Roy-Dufresne

    Full Text Available The white-footed mouse (Peromyscus leucopus is an important reservoir host for Borrelia burgdorferi, the pathogen responsible for Lyme disease, and its distribution is expanding northward. We used an Ecological Niche Factor Analysis to identify the climatic factors associated with the distribution shift of the white-footed mouse over the last 30 years at the northern edge of its range, and modeled its current and potential future (2050 distributions using the platform BIOMOD. A mild and shorter winter is favouring the northern expansion of the white-footed mouse in Québec. With more favorable winter conditions projected by 2050, the distribution range of the white-footed mouse is expected to expand further northward by 3° latitude. We also show that today in southern Québec, the occurrence of B. burgdorferi is associated with high probability of presence of the white-footed mouse. Changes in the distribution of the white-footed mouse will likely alter the geographical range of B. burgdorferi and impact the public health in northern regions that have yet to be exposed to Lyme disease.

  4. California Air Basins

    Data.gov (United States)

    California Department of Resources — Air ResourcesCalifornia Air Resources BoardThe following datasets are from the California Air Resources Board: * arb_california_airbasins - California Air BasinsThe...

  5. Organophosphorus insecticide induced decrease in plasma luteinizing hormone concentration in white-footed mice

    Science.gov (United States)

    Rattner, B.A.; Michael, S.D.

    1985-01-01

    Oral intubation of 50 and 100 mg/kg acephate inhibited brain acetylcholinesterase (AChE) activity by 45% and 56%, and reduced basal luteinizing hormone (LH) concentration by 29% and 25% after 4 h in white-footed mice (Peromyscus leucopus noveboracensis). Dietary exposure to 25, 100, and 400 ppm acephate for 5 days substantially inhibited brain AChE activity, but did not affect plasma LH concentration. These preliminary findings suggest that acute exposure to organophosphorus insecticides may affect LH secretion and possibly reproductive function.

  6. Geology and mammalian paleontology of the Horned Toad Hills, Mojave Desert, California, USA

    Science.gov (United States)

    May, S.R.; Woodburne, M.O.; Lindsay, E.H.; Albright, L.B.; Sarna-Wojcicki, A.; Wan, E.; Wahl, D.B.

    2011-01-01

    The Horned Toad Formation includes five lithostratigraphic members that record alluvial fan, fluvial, lake margin, and lacustrine deposition within a relatively small basin just south of the active Garlock fault during the late Miocene to early Pliocene. These sediments experienced northwest-southeast contractional deformation during the Pliocene-Pleistocene associated with basement-involved reverse faults. Member Two of the Horned Toad Formation has yielded 24 taxa of fossil mammals, referred to as the Warren Local Fauna, including Cryptotis sp., cf. Scapanus, Hypolagus vetus, Hypolagus edensis,? Spermophilus sp., Prothomomys warrenensis n. gen., n. sp., Perognathus sp., Repomys gustelyi, Postcopemys valensis, Peromyscus sp. A, Peromyscus sp. B, Jacobsomys dailyi n. sp., Borophagus cf. B. secundus, cf. Agriotherium, Machairodus sp. cf. M. coloradensis, Rhynchotherium sp. cf. R. edensis, Pliomastodon vexillarius, Dinohippus edensis, Teleoceras sp. cf. T. fossiger, cf. Prosthennops, Megatylopus sp. cf. M. matthewi, Hemiauchenia vera, Camelidae gen. et. sp. indet., and the antilocaprid cf. Sphenophalos. The majority of fossil localities are confined to a 20 m thick stratigraphic interval within a reversed polarity magnetozone. The fauna demonstrates affinity with other late Hemphillian faunas from California, Nevada, Nebraska, Texas, and Mexico. The Lawlor Tuff, dated elsewhere in California at 4.83 ?? 0.04 Ma and geochemically identified in the Horned Toad Formation, overlies most of the fossil mammal localities. Magnetic polarity data are correlated with Chrons 3n.3r, 3n.3n, and 3n.2r, suggesting an age of approximately 5.0 - 4.6 Ma. These constraints indicate an age for the late Hemphillian Warren Local Fauna of 4.85 - 5.0 Ma. ?? Society of Vertebrate Paleontology November 2011.

  7. A High-Resolution Comparative Chromosome Map of Cricetus cricetus and Peromyscus eremicus Reveals the Involvement of Constitutive Heterochromatin in Breakpoint Regions.

    Science.gov (United States)

    Vieira-da-Silva, Ana; Louzada, Sandra; Adega, Filomena; Chaves, Raquel

    2015-01-01

    Compared to humans and other mammals, rodent genomes, specifically Muroidea species, underwent intense chromosome reshuffling in which many complex structural rearrangements occurred. This fact makes them preferential animal models for studying the process of karyotype evolution. Here, we present the first combined chromosome comparative maps between 2 Cricetidae species, Cricetus cricetus and Peromyscus eremicus, and the index species Mus musculus and Rattus norvegicus. Comparative chromosome painting was done using mouse and rat paint probes together with in silico analysis from the Ensembl genome browser database. Hereby, evolutionary events (inter- and intrachromosomal rearrangements) that occurred in C. cricetus and P. eremicus since the putative ancestral Muroidea genome could be inferred, and evolutionary breakpoint regions could be detected. A colocalization of constitutive heterochromatin and evolutionary breakpoint regions in each genome was observed. Our results suggest the involvement of constitutive heterochromatin in karyotype restructuring of these species, despite the different levels of conservation of the C. cricetus (derivative) and P. eremicus (conserved) genomes. PMID:25999143

  8. Persistent Sin Nombre Virus Infection in the Deer Mouse (Peromyscus maniculatus) Model: Sites of Replication and Strand-Specific Expression

    OpenAIRE

    Botten, Jason; Mirowsky, Katy; Kusewitt, Donna; Ye, Chunyan; Gottlieb, Keith; Prescott, Joseph; Hjelle, Brian

    2003-01-01

    To address Sin Nombre (SN) virus persistence in deer mice, we sacrificed experimentally infected deer mice at eight time points from day 21 to day 217 postinoculation (p.i.) and examined their tissues for viral nucleocapsid (N) antigen expression and both negative-strand (genomic) and positive-strand (replicative/mRNA) viral S segment RNA titers. All the animals that we inoculated developed persistent infections, and SN virus could be isolated from tissues throughout the course of infection. ...

  9. California Political Districts

    Data.gov (United States)

    California Department of Resources — This is a series of district layers pertaining to California'spolitical districts, that are derived from the California State Senateand State Assembly information....

  10. Molecular epidemiology of Bartonella species isolated from ground squirrels and other rodents in northern California.

    Science.gov (United States)

    Ziedins, A C; Chomel, B B; Kasten, R W; Kjemtrup, A M; Chang, C-C

    2016-07-01

    Bartonella spp. are endemic in wild rodents in many parts of the world. A study conducted in two northern California counties (Sonoma and Yolo) sampling California ground squirrels (Otospermophilus beecheyi) and four other rodent species (Peromyscus maniculatus, P. boylii, P. truei and Neotoma fuscipes) led to the isolation of small Gram-negative bacilli which were identified as Bartonella spp. based on colony morphology, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and partial gene sequencing. Overall, Bartonella spp. were isolated from the blood of 71% (32/45) of the ground squirrels and one third (22/66) of the other rodents. PCR-RFLP analysis of the gltA and 16S rRNA genes yielded seven unique profiles, four for the ground squirrels and three for the other rodents. Isolates from each PCR-RFLP profiles were submitted for partial sequencing. Ground squirrel isolates were most closely related to B. washoensis, whereas the other rodent isolates were closest to B. vinsonii subsp. vinsonii and B. vinsonii subsp. arupensis. Two of these three species or subspecies are known zoonotic agents. PMID:27245290

  11. Teale California shoreline

    Data.gov (United States)

    California Department of Resources — California Spatial Information System (CaSIL) is a project designed to improve access to geo-spatial and geo-spatial related data information throughout the state...

  12. California Condor Critical Habitat

    Data.gov (United States)

    California Department of Resources — These Data identify (in general) the areas where critical habitat for the California Condor occur. Critical habitat for the species consists of the following 10...

  13. Genetic differences in hemoglobin function between highland and lowland deer mice

    DEFF Research Database (Denmark)

    Storz, Jay F.; Runck, Amy M.; Moriyama, Hideaki;

    2010-01-01

    of mammalian species that are high-altitude natives. Here we investigated genetically based differences in Hb–O2 affinity between highland and lowland populations of the deer mouse (Peromyscus maniculatus), a generalist species that has the broadest altitudinal distribution of any North American...... mammal. The results of a combined genetic and proteomic analysis revealed that deer mice harbor a high level of Hb isoform diversity that is attributable to allelic polymorphism at two tandemly duplicated -globin genes and two tandemly duplicated β-globin genes. This high level of isoHb diversity...... experiments also revealed distinct biochemical properties of deer mouse Hb related to the anion-dependent allosteric regulation of O2 affinity. In conjunction with previous findings, our results demonstrate that modifications of Hb structure that alter allosteric anion sensitivity play an important role in...

  14. Reemerging Leptospirosis, California

    OpenAIRE

    Meites, Elissa; Jay, Michele T.; Deresinski, Stanley; Shieh, Wun-Ju; Zaki, Sherif R.; Tompkins, Lucy; Smith, D. Scott

    2004-01-01

    Leptospirosis is a reemerging infectious disease in California. Leptospirosis is the most widespread zoonosis throughout the world, though it is infrequently diagnosed in the continental United States. From 1982 to 2001, most reported California cases occurred in previously healthy young adult white men after recreational exposures to contaminated freshwater. We report five recent cases of human leptospirosis acquired in California, including the first documented common-source outbreak of hum...

  15. California's congestion management program

    International Nuclear Information System (INIS)

    One of the hottest topics in transportation planning today is California's Congestion Management Program (CMP). California's program has been suggested as a model to the rest of the United States for addressing transportation problems and for conforming to the federal Clean Air Act. This article introduces California's Congestion Management Program, describes some problems related to California's CMP legislation, outlines the major CMP elements, and briefly explains the issue of the environmental impact of CMPs. This information might assist others in developing their own CMP programs

  16. Effect of Woody Debris abundance on daytime refuge use by cotton mice.

    Energy Technology Data Exchange (ETDEWEB)

    Hinkelman, Travis, M.; Loeb, Susan, C.

    2007-07-01

    Abstract - Daytime refuges are important to nocturnal rodents for protection from predators and environmental extremes. Because refuges of forest-dwelling rodents are often associated with woody debris, we examined refuge use by 37 radio-collared Peromyscus gossypinus (cotton mice) in experimental plots with different levels of woody debris. Treatment plots had six times (≈ 60 m3/ha) the volume of woody debris as control plots (≈ 10 m3/ha). Of 247 refuges, 159 were in rotting stumps (64%), 32 were in root boles (13%), 19 were in brush piles (8%), and 16 were in logs (6%); 10 refuges could not be identified. Stumps were the most common refuge type in both treatments, but the distribution of refuge types was significantly different between treatment and control plots. Root boles and brush piles were used more on treatment plots than on control plots, and logs were used more on control plots than on treatment plots. Refuge type and vegetation cover were the best predictors of refuge use by cotton mice; root bole refuges and refuges with less vegetation cover received greater-than-expected use by mice. Abundant refuges, particularly root boles, may improve habitat quality for cotton mice in southeastern pine forests.

  17. California's English Learner Students

    Science.gov (United States)

    Hill, Laura E.

    2012-01-01

    English Learner (EL) students in California's schools are numerous and diverse, and they lag behind their native-English-speaking peers. Closing the achievement gap for EL students has been a long-standing goal for California educators, and there are some signs of success. Now that EL funding and curriculum issues are receiving a fresh level of…

  18. Effects of fire on small mammal communities in frequent-fire forests in California

    Science.gov (United States)

    Roberts, Susan L.; Kelt, Douglas A.; Van Wagtendonk, Jan W.; Miles, A. Keith; Meyer, Marc D.

    2015-01-01

    Fire is a natural, dynamic process that is integral to maintaining ecosystem function. The reintroduction of fire (e.g., prescribed fire, managed wildfire) is a critical management tool for protecting many frequent-fire forests against stand-replacing fires while restoring an essential ecological process. Understanding the effects of fire on forests and wildlife communities is important in natural resource planning efforts. Small mammals are key components of forest food webs and essential to ecosystem function. To investigate the relationship of fire to small mammal assemblages, we live trapped small mammals in 10 burned and 10 unburned forests over 2 years in the central Sierra Nevada, California. Small mammal abundance was higher in unburned forests, largely reflecting the greater proportion of closed-canopy species such as Glaucomys sabrinus in unburned forests. The most abundant species across the entire study area was the highly adaptable generalist species, Peromyscus maniculatus. Species diversity was similar between burned and unburned forests, but burned forests were characterized by greater habitat heterogeneity and higher small mammal species evenness. The use and reintroduction of fire to maintain a matrix of burn severities, including large patches of unburned refugia, creates a heterogeneous and resilient landscape that allows for fire-sensitive species to proliferate and, as such, may help maintain key ecological functions and diverse small mammal assemblages.

  19. Impacts of an introduced forest pathogen on the risk of Lyme disease in California.

    Science.gov (United States)

    Swei, Andrea; Briggs, Cheryl J; Lane, Robert S; Ostfeld, Richard S

    2012-08-01

    Global changes such as deforestation, climate change, and invasive species have the potential to greatly alter zoonotic disease systems through impacts on biodiversity. This study examined the impact of the invasive pathogen that causes sudden oak death (SOD) on the ecology of Lyme disease in California. The Lyme disease bacterium, Borrelia burgdorferi, is maintained in the far western United States by a suite of animal reservoirs including the dusky-footed woodrat (Neotoma fuscipes) and deer mouse (Peromyscus maniculatus), and is transmitted by the western black-legged tick (Ixodes pacificus). Other vertebrates, such as the western fence lizard (Sceloporus occidentalis), are important tick hosts but are not reservoirs of the pathogen. Previous work found that higher levels of SOD are correlated with greater abundance of P. maniculatus and S. occidentalis and lower N. fuscipes abundance. Here we model the contribution of these tick hosts to Lyme disease risk and also evaluate the potential impact of SOD on infection prevalence of the tick vector. By empirically parameterizing a static model with field and laboratory data on tick hosts, we predict that SOD reduces an important index of disease risk, nymphal infection prevalence, leading to a reduction in Lyme disease risk in certain coastal woodlands. Direct observational analysis of the impact of SOD on nymphal infection prevalence supports these model results. This study underscores the important direct and indirect impacts of invasive plant pathogens on biodiversity, the transmission cycles of zoonotic diseases, and ultimately human health. PMID:22607076

  20. Census Snapshot: California

    OpenAIRE

    Romero, Adam P; Rosky, Clifford J; Badgett, M. V. Lee; Gates, Gary J.

    2008-01-01

    Using data from the U.S. Census Bureau, this report provides demographic and economic information about same-sex couples and same-sex couples raising children in California. We compare same-sex “unmarried partners,” which the Census Bureau defines as an unmarried couple who “shares living quarters and has a close personal relationship,” to different-sex married couples in California. In many ways, the more than 107,000 same-sex couples living in California are similar to married coup...

  1. California Immigrants Today

    OpenAIRE

    Cornelius, Wayne A.

    1990-01-01

    This paper will focus on the Mexico-origin component of the California immigrant population. Drawing on the results of field studies conducted throughout California and in west-central Mexico during the last ten years,the paper will describe how the profile of Mexican migration to California has changed since the 197Os, suggest explanations for these changes, and discuss their implications for public policy. Effects of the long-running economic crisis in Mexico and of the 1986 U.S. immigra-ti...

  2. An Experimental Test of Competition among Mice, Chipmunks, and Squirrels in Deciduous Forest Fragments.

    Directory of Open Access Journals (Sweden)

    Jesse L Brunner

    Full Text Available Mixed hardwood forests of the northeast United States support a guild of granivorous/omnivorous rodents including gray squirrels (Sciurus carolinensis, eastern chipmunks (Tamias striatus, and white-footed mice (Peromyscus leucopus. These species coincide geographically, co-occur locally, and consume similar food resources. Despite their idiosyncratic responses to landscape and patch variables, patch occupancy models suggest that competition may influence their respective distributions and abundances, and accordingly their influence on the rest of the forest community. Experimental studies, however, are wanting. We present the result of a large-scale experiment in which we removed white-footed mice or gray squirrels from small, isolated forest fragments in Dutchess County, New York, and added these mammals to other fragments in order to alter the abundance of these two species. We then used mark-recapture analyses to quantify the population-level and individual-level effects on resident mice, squirrels, and chipmunks. Overall, we found little evidence of competition. There were essentially no within-season numerical responses to changes in the abundance of putative competitors. Moreover, while individual-level responses (apparent survival and capture probability did vary with competitor densities in some models, these effects were often better explained by site-specific parameters and were restricted to few of the 19 sites we studied. With only weak or nonexistent competition among these three common rodent species, we expect their patterns of habitat occupancy and population dynamics to be largely independent of one another.

  3. California Data Exchange Center

    Science.gov (United States)

    ... to make July &28;Water Smart Month.&29; &28;Conserving ... Remote sensors today indicate that statewide, snowpack water content is 54 percent of ... California ranked first, along with Texas, on ...

  4. Earthquakes in Southern California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — There have been many earthquake occurrences in Southern California. This set of slides shows earthquake damage from the following events: Imperial Valley, 1979,...

  5. Coastal California Digital Imagery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This digital ortho-imagery dataset is a survey of coastal California. The project area consists of approximately 3774 square miles. The project design of the...

  6. California Ocean Uses Atlas

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset is a result of the California Ocean Uses Atlas Project: a collaboration between NOAA's National Marine Protected Areas Center and Marine Conservation...

  7. Kelp distribution off California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set delineates kelp beds (Nereocystis leutkeana and Macrocystis spp.) along the Pacific Coast of California. Multiple years of kelp mapping data for the...

  8. California Harpoon Fishery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains vessel logbook and landings data from harpoon vessels that fish within 200 miles of the California coast, from 1974 to present. The harpoon...

  9. California Watershed Hydrologic Units

    Data.gov (United States)

    California Department of Resources — This dataset is intended to be used as a tool for water-resource management and planning activities, particularly for site-specific and localized studies requiring...

  10. The California Hazards Institute

    Science.gov (United States)

    Rundle, J. B.; Kellogg, L. H.; Turcotte, D. L.

    2006-12-01

    California's abundant resources are linked with its natural hazards. Earthquakes, landslides, wildfires, floods, tsunamis, volcanic eruptions, severe storms, fires, and droughts afflict the state regularly. These events have the potential to become great disasters, like the San Francisco earthquake and fire of 1906, that overwhelm the capacity of society to respond. At such times, the fabric of civic life is frayed, political leadership is tested, economic losses can dwarf available resources, and full recovery can take decades. A patchwork of Federal, state and local programs are in place to address individual hazards, but California lacks effective coordination to forecast, prevent, prepare for, mitigate, respond to, and recover from, the harmful effects of natural disasters. Moreover, we do not know enough about the frequency, size, time, or locations where they may strike, nor about how the natural environment and man-made structures would respond. As California's population grows and becomes more interdependent, even moderate events have the potential to trigger catastrophes. Natural hazards need not become natural disasters if they are addressed proactively and effectively, rather than reactively. The University of California, with 10 campuses distributed across the state, has world-class faculty and students engaged in research and education in all fields of direct relevance to hazards. For that reason, the UC can become a world leader in anticipating and managing natural hazards in order to prevent loss of life and property and degradation of environmental quality. The University of California, Office of the President, has therefore established a new system-wide Multicampus Research Project, the California Hazards Institute (CHI), as a mechanism to research innovative, effective solutions for California. The CHI will build on the rich intellectual capital and expertise of the Golden State to provide the best available science, knowledge and tools for

  11. Increased Detection of Sin Nombre Hantavirus RNA in Antibody-Positive Deer Mice from Montana, USA: Evidence of Male Bias in RNA Viremia

    Directory of Open Access Journals (Sweden)

    James N. Mills

    2013-09-01

    Full Text Available Hantaviruses are widespread emergent zoonotic agents that cause unapparent or limited disease in their rodent hosts, yet cause acute, often fatal pulmonary or renal infections in humans. Previous laboratory experiments with rodent reservoir hosts indicate that hantaviruses can be cleared from host blood early in the infection cycle, while sequestered long term in various host organs. Field studies of North American deer mice (Peromyscus maniculatus, the natural reservoir of Sin Nombre hantavirus, have shown that viral RNA can be transiently detected well past the early acute infection stage, but only in the minority of infected mice. Here, using a non-degenerate RT-PCR assay optimized for SNV strains known to circulate in Montana, USA, we show that viral RNA can be repeatedly detected on a monthly basis in up to 75% of antibody positive deer mice for periods up to 3–6 months. More importantly, our data show that antibody positive male deer mice are more than twice as likely to have detectable SNV RNA in their blood as antibody positive females, suggesting that SNV-infected male deer mice are more likely to shed virus and for longer periods of time.

  12. The Story of California = La Historia de California.

    Science.gov (United States)

    Bartel, Nick

    "The Story of California" is a history and geography of the state of California, intended for classroom use by limited-English-proficient, native Spanish-speaking students in California's urban middle schools. The book is designed with the left page in English and the right page in Spanish to facilitate student transition into comfortable use of…

  13. California's Future Carbon Flux

    Science.gov (United States)

    Xu, L.; Pyles, R. D.; Paw U, K.; Gertz, M.

    2008-12-01

    The diversity of the climate and vegetation systems in the state of California provides a unique opportunity to study carton dioxide exchange between the terrestrial biosphere and the atmosphere. In order to accurately calculate the carbon flux, this study couples the sophisticated analytical surface layer model ACASA (Advance Canopy-Atmosphere-Soil Algorithm, developed in the University of California, Davis) with the newest version of mesoscale model WRF (the Weather Research & Forecasting Model, developed by NCAR and several other agencies). As a multilayer, steady state model, ACASA incorporates higher-order representations of vertical temperature variations, CO2 concentration, radiation, wind speed, turbulent statistics, and plant physiology. The WRF-ACASA coupling is designed to identify how multiple environmental factors, in particularly climate variability, population density, and vegetation distribution, impact on future carbon cycle prediction across a wide geographical range such as in California.

  14. Baylisascaris procyonis infection in white-footed mice: predicting patterns of infection from landscape habitat attributes.

    Science.gov (United States)

    Beasley, J C; Eagan, T S; Page, L K; Hennessy, C A; Rhodes, O E

    2013-10-01

    There is a growing body of evidence that habitat fragmentation resulting from anthropogenic land use can alter the transmission dynamics of infectious disease. Baylisascaris procyonis , a parasitic roundworm with the ability to cause fatal central nervous system disease in many mammals, including humans, is a zoonotic threat, and research suggests that parasite recruitment rates by intermediate hosts are highly variable among forest patches in fragmented landscapes. During 2008, we sampled 353 white-footed mice ( Peromyscus leucopus ) from 22 forest patches distributed throughout a fragmented agricultural ecosystem to determine the influence of landscape-level habitat attributes on infection rates of B. procyonis in mice. We characterized each mouse in terms of infection status and intensity of infection, and calculated (on a patch-wide basis) prevalence, mean abundance of B. procyonis , and mean intensity of infection. We used an information-theoretic approach to develop a suite of candidate models characterizing the influence of landscape attributes on each of our measured characteristics of B. procyonis infection in white-footed mice, based on previous knowledge of raccoon ( Procyon lotor ) ecology and B. procyonis distribution in agricultural ecosystems. We observed evidence of B. procyonis infection in mice across all 22 habitat patches sampled. However, parasite recruitment rates and intensity were highly variable among patches, and the results of our analyses suggest that spatial variability in B. procyonis infections was primarily driven by emergent properties of fragmented ecosystems. In particular, prevalence, abundance, and intensity of B. procyonis infections in mice were negatively associated with the size and connectivity of forest patches. These results support previous studies indicating that habitat fragmentation can alter the transmission dynamics of infectious disease, and suggest that factors below the scale of landscape, i.e., fine

  15. California Indian Food and Culture.

    Science.gov (United States)

    2001

    This learning kit begins with a glossary of terms to help students learn about California Indians and their food. The kit explains that California Indians were the first people to live in the area now known as California, and that these tribes differed in the languages they spoke, the regions they lived in, and the foods that they ate. It explains…

  16. Adaptive variation in beach mice produced by two interacting pigmentation genes.

    Directory of Open Access Journals (Sweden)

    Cynthia C Steiner

    2007-09-01

    Full Text Available Little is known about the genetic basis of ecologically important morphological variation such as the diverse color patterns of mammals. Here we identify genetic changes contributing to an adaptive difference in color pattern between two subspecies of oldfield mice (Peromyscus polionotus. One mainland subspecies has a cryptic dark brown dorsal coat, while a younger beach-dwelling subspecies has a lighter coat produced by natural selection for camouflage on pale coastal sand dunes. Using genome-wide linkage mapping, we identified three chromosomal regions (two of major and one of minor effect associated with differences in pigmentation traits. Two candidate genes, the melanocortin-1 receptor (Mc1r and its antagonist, the Agouti signaling protein (Agouti, map to independent regions that together are responsible for most of the difference in pigmentation between subspecies. A derived mutation in the coding region of Mc1r, rather than change in its expression level, contributes to light pigmentation. Conversely, beach mice have a derived increase in Agouti mRNA expression but no changes in protein sequence. These two genes also interact epistatically: the phenotypic effects of Mc1r are visible only in genetic backgrounds containing the derived Agouti allele. These results demonstrate that cryptic coloration can be based largely on a few interacting genes of major effect.

  17. SOUTH WARNER WILDERNESS, CALIFORNIA.

    Science.gov (United States)

    Duffield, Wendell A.; Weldin, Robert E.

    1984-01-01

    A mineral appraisal utilized geologic, geochemical, and geophysical data and an examination of mining claims in the South Warner Wilderness, California. Results of this study indicate that little promise for the occurrence of mineral resources exists within the area. Small veins of optical quality calcite occur on the east side of the area but, are not considered a resource.

  18. Transcriptomic plasticity in brown adipose tissue contributes to an enhanced capacity for nonshivering thermogenesis in deer mice.

    Science.gov (United States)

    Velotta, Jonathan P; Jones, Jennifer; Wolf, Cole J; Cheviron, Zachary A

    2016-06-01

    For small mammals living at high altitude, aerobic heat generation (thermogenesis) is essential for survival during prolonged periods of cold, but is severely impaired under conditions of hypobaric hypoxia. Recent studies in deer mice (Peromyscus maniculatus) reveal adaptive enhancement of thermogenesis in high- compared to low-altitude populations under hypoxic cold stress, an enhancement that is attributable to modifications in the aerobic metabolism of muscles used in shivering. However, because small mammals rely heavily on nonshivering mechanisms for cold acclimatization, we tested for evidence of adaptive divergence in nonshivering thermogenesis (NST) under hypoxia. To do so, we measured NST and characterized transcriptional profiles of brown adipose tissue (BAT) in high- and low-altitude deer mice that were (i) wild-caught and acclimatized to their native altitude, and (ii) born and reared under common garden conditions at low elevation. We found that NST performance under hypoxia is enhanced in wild-caught, high-altitude deer mice, a difference that is associated with increased expression of coregulated genes that influence several physiological traits. These traits include vascularization and O2 supply to BAT, brown adipocyte proliferation and the uncoupling of oxidative phosphorylation from ATP synthesis in the generation of heat. Our results suggest that acclimatization to hypoxic cold stress is facilitated by enhancement of nonshivering heat production, which is driven by regulatory plasticity in a suite of genes that influence intersecting physiological pathways. PMID:27126783

  19. Hypothalamic vasopressin systems are more sensitive to the long term effects of social defeat in males versus females

    OpenAIRE

    Steinman, M.Q.; Laredo, S.A.; Lopez, E.M.; Manning, C E; Hao, R.C.; Doig, I.E.; Campi, K.L.; Flowers, A.E.; Knight, J.K.; Trainor, B.C.

    2014-01-01

    Vasopressin signaling has important effects on the regulation of social behaviors and stress responses, and is considered a promising pathway to target for new therapeutics of stress-induced psychiatric disorders. Although there is evidence for sex differences in the behavioral effects of arginine vasopressin (AVP), few data have directly compared the effects of stress on endogenous AVP signaling in males and females. We used California mice (Peromyscus californicus) to study the short and lo...

  20. Sex differences in stress-induced social withdrawal: independence from adult gonadal hormones and inhibition of female phenotype by corncob bedding

    OpenAIRE

    Trainor, Brian C.; Takahashi, Elizabeth Y.; Campi, Katharine L.; Florez, Stefani A.; Greenberg, Gian D.; Laman-Maharg, Abigail; Laredo, Sarah A.; Orr, Veronica N.; Silva, Andrea L.; Steinman, Michael Q.

    2013-01-01

    There is compelling evidence for important sex differences in behavioral and hormonal responses to psychosocial stress. Here we examined the effects of gonadal hormones on behavioral responses to social defeat stress in monogamous California mice (Peromyscus californicus). Three episodes of social defeat induced social withdrawal in intact females but not males. Gonadectomy blocked corticosterone responses to defeat in females and sensitized male corticosterone responses. However, gonadectomy...

  1. Sex differences in effects of dopamine D1 receptors on social withdrawal

    OpenAIRE

    Campi, Katharine L.; Greenberg, Gian D.; Kapoor, Amita; Ziegler, Toni E.; Trainor, Brian C.

    2013-01-01

    Dopamine signaling in the nucleus accumbens (NAc) plays a critical role in the regulation of motivational states. Recent studies in male rodents show that social defeat stress increases the activity of ventral tegmental dopamine neurons projecting to the NAc, and that this increased activity is necessary for stress-induced social withdrawal. Domestic female mice are not similarly aggressive, which has hindered complementary studies in females. Using the monogamous California mouse (Peromyscus...

  2. Sex differences in effects of dopamine D1 receptors on social withdrawal

    OpenAIRE

    Campi, KL; Greenberg, GD; Kapoor, A.; Ziegler, TE; Trainor, BC

    2014-01-01

    Dopamine signaling in the nucleus accumbens (NAc) plays a critical role in the regulation of motivational states. Recent studies in male rodents show that social defeat stress increases the activity of ventral tegmental dopamine neurons projecting to the NAc, and that this increased activity is necessary for stress-induced social withdrawal. Domestic female mice are not similarly aggressive, which has hindered complementary studies in females. Using the monogamous California mouse (Peromyscus...

  3. Hypothalamic vasopressin systems are more sensitive to the long term effects of social defeat in males versus females

    OpenAIRE

    Steinman, MQ; Laredo, SA; Lopez, EM; Manning, CE; Hao, RC; Doig, IE; Campi, KL; Flowers, AE; Knight, JK; Trainor, BC

    2015-01-01

    © 2014 Elsevier Ltd. Vasopressin signaling has important effects on the regulation of social behaviors and stress responses, and is considered a promising pathway to target for new therapeutics of stress-induced psychiatric disorders. Although there is evidence for sex differences in the behavioral effects of arginine vasopressin (AVP), few data have directly compared the effects of stress on endogenous AVP signaling in males and females. We used California mice (. Peromyscus californicus) to...

  4. Humanized mice

    OpenAIRE

    Macchiarini, Francesca; Manz, Markus G.; Palucka, A Karolina; Shultz, Leonard D.

    2005-01-01

    Animal models have been instrumental in increasing the understanding of human physiology, particularly immunity. However, these animal models have been limited by practical considerations and genetic diversity. The creation of humanized mice that carry partial or complete human physiological systems may help overcome these obstacles. The National Institute of Allergy and Infectious Diseases convened a workshop on humanized mouse models for immunity in Bethesda, MD, on June 13–14, 2005, during...

  5. MICE Overview

    OpenAIRE

    Coney, L

    2009-01-01

    Muon ionization cooling provides the only practical solution for preparing high brightness beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE) is under development at the Rutherford Appleton Laboratory (UK). It comprises a dedicated beam line designed to generate a range of input emittances and momenta with time-of-flight and Cherenkov detectors to select a pure muon beam. A first measurement of emittance is performed in the upstream magnetic...

  6. Accounting for California Water

    OpenAIRE

    Escriva-Bou, Alvar; McCann, Henry; Hanak, Ellen; Lund, Jay; Gray, Brian

    2016-01-01

    Understanding California’s water balance sheet—how much there is, who has claims to it, and what is actually being “spent”—is key to effectively managing the state’s limited water supply in support of a healthy economy and environment. The latest drought has spotlighted serious gaps in California’s water accounting system. California is a large, geographically diverse state, and its water systems are physically interconnected and institutionally fragmented. Water infrastructure connects the s...

  7. Obesity in California, 2012 and 2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — These data are from the 2013 California Dietary Practices Surveys (CDPS), 2012 California Teen Eating, Exercise and Nutrition Survey (CalTEENS), and 2013 California...

  8. California community water systems inventory dataset, 2010

    Data.gov (United States)

    California Environmental Health Tracking Program — This data set contains information about all Community Water Systems in California. Data are derived from California Office of Drinking Water (ODW) Water Quality...

  9. California's geothermal resource potential

    Science.gov (United States)

    Leibowitz, L. P.

    1978-01-01

    According to a U.S. Geological Survey estimate, recoverable hydrothermal energy in California may amount to 19,000 MW of electric power for a 30-year period. At present, a geothermal installation in the Geysers region of the state provides 502 MWe of capacity; an additional 1500 MWe of electric generating capacity is scheduled to be in operation in geothermal fields by 1985. In addition to hydrothermal energy sources, hot-igneous and conduction-dominated resources are under investigation for possible development. Land-use conflicts, environmental concerns and lack of risk capital may limit this development.

  10. California Tiger Salamander Range - CWHR [ds588

    Data.gov (United States)

    California Department of Resources — Vector datasets of CWHR range maps are one component of California Wildlife Habitat Relationships (CWHR), a comprehensive information system and predictive model...

  11. California Fish Passage Assessment Database [ds69

    Data.gov (United States)

    California Department of Resources — The Passage Assessment Database shapefile contains locations of known and potential barriers to salmonid migration in California streams with additional information...

  12. Giant Reed Distribution - Northern California [ds333

    Data.gov (United States)

    California Department of Resources — The Arundo Distribution layer is a compilation of Arundo donax observations in northern and central California, obtained from several sources, including Arundo...

  13. Experts Question California's Algebra Edict

    Science.gov (United States)

    Cavanagh, Sean

    2008-01-01

    Business leaders from important sectors of the American economy have been urging schools to set higher standards in math and science--and California officials, in mandating that 8th graders be tested in introductory algebra, have responded with one of the highest such standards in the land. Still, many California educators and school…

  14. Resource Cards on California Schools

    Science.gov (United States)

    EdSource, 2007

    2007-01-01

    This convenient spiral-bound volume contains the latest data on school finance as well as information on students, teachers, and California's accountability system. The 37-card 2007 edition provides fingertip access to the latest information about California's education system. They are separated into sections that cover related topics. Each…

  15. Female Superintendent Longevity in California

    Science.gov (United States)

    Rohlfing, Tracy

    2011-01-01

    The purpose of this study was to investigate, through narrative inquiry (Clandinin & Connelly, 2000), the leadership evolution of five female superintendents in California with longevity of 5 or more years in their current school district positions. The research question addressed was, "How do California female superintendents evolve to…

  16. Hydrogen energy system in California

    International Nuclear Information System (INIS)

    Results of experiences on the use of hydrogen as a clean burning fuel in California and results of the South Coast Air Quality Management district tests using hydrogen as a clean burning environmentally safe fuel are given. The results of Solar Hydrogen Projects in California and recent medical data documentation of human lung damage of patients living in air polluted urban areas are summarized

  17. Isolation and Characterization of Borrelia hermsii Associated with Two Foci of Tick-Borne Relapsing Fever in California

    OpenAIRE

    Fritz, Curtis L; Bronson, Lawrence R.; Smith, Charles R.; Schriefer, Martin E.; Tucker, James R.; Schwan, Tom G.

    2004-01-01

    Relapsing fever, caused by the spirochete Borrelia hermsii and transmitted by the soft tick Ornithodoros hermsi, is endemic in many rural mountainous areas of California. Between 1996 and 1998, 12 cases of relapsing fever associated with two exposure sites in northern California were investigated. Follow-up at exposure sites included collection of soft ticks and serum specimens from sylvatic rodents. Attempts to cultivate spirochetes were made through inoculation of patient blood into mice an...

  18. MICE Overview

    CERN Document Server

    Coney, L

    2009-01-01

    Muon ionization cooling provides the only practical solution for preparing high brightness beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE) is under development at the Rutherford Appleton Laboratory (UK). It comprises a dedicated beam line designed to generate a range of input emittances and momenta with time-of-flight and Cherenkov detectors to select a pure muon beam. A first measurement of emittance is performed in the upstream magnetic spectrometer with a scintillating fiber tracker. A cooling cell will then follow, alternating energy loss in liquid hydrogen and acceleration by RF cavities. A second spectrometer identical to the first and another particle identification system provide a measurement of the outgoing emittance. In late 2009, it is expected that the beam and many of the particle identification detectors will be in the final commissioning phase, and the first measurement of input beam emittance will take place in 2010. The steps of commissi...

  19. Bohr effect and temperature sensitivity of hemoglobins from highland and lowland deer mice.

    Science.gov (United States)

    Jensen, Birgitte; Storz, Jay F; Fago, Angela

    2016-05-01

    An important means of physiological adaptation to environmental hypoxia is an increased oxygen (O2) affinity of the hemoglobin (Hb) that can help secure high O2 saturation of arterial blood. However, the trade-off associated with a high Hb-O2 affinity is that it can compromise O2 unloading in the systemic capillaries. High-altitude deer mice (Peromyscus maniculatus) have evolved an increased Hb-O2 affinity relative to lowland conspecifics, but it is not known whether they have also evolved compensatory mechanisms to facilitate O2 unloading to respiring tissues. Here we investigate the effects of pH (Bohr effect) and temperature on the O2-affinity of high- and low-altitude deer mouse Hb variants, as these properties can potentially facilitate O2 unloading to metabolizing tissues. Our experiments revealed that Bohr factors for the high- and low-altitude Hb variants are very similar in spite of the differences in O2-affinity. The Bohr factors of deer mouse Hbs are also comparable to those of other mammalian Hbs. In contrast, the high- and low-altitude variants of deer mouse Hb exhibited similarly low temperature sensitivities that were independent of red blood cell anionic cofactors, suggesting an appreciable endothermic allosteric transition upon oxygenation. In conclusion, high-altitude deer mice have evolved an adaptive increase in Hb-O2 affinity, but this is not associated with compensatory changes in sensitivity to changes in pH or temperature. Instead, it appears that the elevated Hb-O2 affinity in high-altitude deer mice is compensated by an associated increase in the tissue diffusion capacity of O2 (via increased muscle capillarization), which promotes O2 unloading. PMID:26808972

  20. 1991 : California gas wars explode

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2008-06-15

    In 1991, the California Public Utilities Commission (CPUC) made an attempt to make the California energy market more competitive and targeted the long-standing relationship between gas producers in Alberta and California's gas distributor Pacific Gas and Electric (PG and E). The utility's buying division, Alberta and Southern Gas, had offered a new contract to Alberta producers that would have resulted in a 25 per cent price reduction. The market represented $1 billion annual revenue for Alberta producers, with 40 per cent of Canadian gas exports going to California. The former chief economist with the United States Senate Energy Committee estimated that Alberta producers were overcharging California ratepayers by $250 million per year. Other key events in 1991 included the National Energy Board's announcement that it would move its headquarters to Calgary, and Nova Corporation sold its 43 per cent stake in Husky Oil. 1 tab., 1 fig.

  1. Progress in California

    Energy Technology Data Exchange (ETDEWEB)

    Gipe, P.

    1990-01-01

    Though the wind energy continues to take it on the chin in the rough and tumble of California's celebrity politics, several indicators are pointing toward a modest revival. First several new reports laud wind energy at good sites as now competitive with conventional sources. Second, utility subsidiaries are signaling their approval by cautiously venturing into the technology. Also, technological refinements and reorganizations continue while a demand for new generating capacity may be developing in the state. Three new reports all paint a picture of wind energy finally coming of age. The California Energy Commission's most recent Energy Technology Status report says that wind-generated electricity is competitive with coal, oil, gas, and most other technologies. Similarly, a staff report found that after tallying the economic, social, and environmental costs, wind was one of the least cost sources of new generation. Most recently the Electric Power Research Institute's Journal reported the wind energy, at about 8 cents/k Wh, is equivalent to generation from conventional sources.

  2. DS796 California Groundwater Units

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The California Groundwater Units dataset classifies and delineates the State into one of three groundwater based polygon units: (1) those areas defined as alluvial...

  3. Habitat--Offshore Monterey, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Monterey map area, California. The vector data file is included in...

  4. Invertebrate diversity in southern California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This shapefile displays mean invertebrate diversity within 5 minute grid cells. The Shannon Index of diversity was calculated from Southern California Coastal Water...

  5. Chukar Range - California [ds570

    Data.gov (United States)

    California Department of Resources — This layer was created from regional biologist input on paper maps. All paper maps were collected and sent to a single Research Analyst to digitize. Some liberties...

  6. Contours--Offshore Monterey, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents bathymetric contours for several seafloor maps of the Monterey Canyon and Vicinity map area, California. The raster data file is...

  7. Flight tracks, Northern California TRACON

    Data.gov (United States)

    National Aeronautics and Space Administration — This dataset contains the records of all the flights in the Northern California TRACON. The data was provided by the aircraft noise abatement office...

  8. Bathymetry--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of the Offshore of Bolinas, California (raster data file is included in...

  9. Bathymetry--Offshore Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore Pacifica, California. The raster data file is included in...

  10. Contours--Offshore Aptos, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Aptos map area, California. The vector data file is...

  11. The California cogeneration success story

    International Nuclear Information System (INIS)

    This chapter describes the involvement of Southern California Gas Company(SoCalGas) in the promotion and demonstration of the benefits of cogeneration in California. The topics covered in this chapter are market strategy, cogeneration program objectives, cogeneration program, incentive cofunding, special gas rate, special service priority, special gas pressure and main options, advertising, promotional brochures and handbooks, technical support, program accomplishments, cogeneration outlook, and reasons for success of the program

  12. California Gnatcatcher Observations - 2004-2009 [ds457

    Data.gov (United States)

    California Department of Resources — In southern California, the coastal California gnatcatcher (CAGN) has become both the flagship species and an umbrella species identified with conservation, where...

  13. Stereo Pair, Pasadena, California

    Science.gov (United States)

    2000-01-01

    This stereoscopic image pair is a perspective view that shows the western part of the city of Pasadena, California, looking north toward the San Gabriel Mountains. Portions of the cities of Altadena and La Canada Flintridge are also shown. The cluster of large buildings left of center, at the base of the mountains, is the Jet Propulsion Laboratory. This image shows the power of combining data from different sources to create planning tools to study problems that affect large urban areas. In addition to the well-known earthquake hazards, Southern California is affected by a natural cycle of fire and mudflows. Data shown in this image can be used to predict both how wildfires spread over the terrain and how mudflows are channeled down the canyons.The image was created from three datasets: the Shuttle Radar Topography Mission (SRTM) supplied the elevation, U. S. Geological Survey digital aerial photography provided the image detail, and the Landsat Thematic Mapper provided the color. The United States Geological Survey's Earth Resources Observations Systems (EROS) Data Center, Sioux Falls, South Dakota, provided the Landsat data and the aerial photography. The image can be viewed in 3-D by viewing the left image with the right eye and the right image with the left eye (cross-eyed viewing), or by downloading and printing the image pair, and viewing them with a stereoscope.The Shuttle Radar Topography Mission (SRTM), launched on February 11, 2000, used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. The mission was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, an additional C-band imaging antenna and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA

  14. Fire risk in California

    Science.gov (United States)

    Peterson, Seth Howard

    Fire is an integral part of ecosystems in the western United States. Decades of fire suppression have led to (unnaturally) large accumulations of fuel in some forest communities, such as the lower elevation forests of the Sierra Nevada. Urban sprawl into fire prone chaparral vegetation in southern California has put human lives at risk and the decreased fire return intervals have put the vegetation community at risk of type conversion. This research examines the factors affecting fire risk in two of the dominant landscapes in the state of California, chaparral and inland coniferous forests. Live fuel moisture (LFM) is important for fire ignition, spread rate, and intensity in chaparral. LFM maps were generated for Los Angeles County by developing and then inverting robust cross-validated regression equations from time series field data and vegetation indices (VIs) and phenological metrics from MODIS data. Fire fuels, including understory fuels which are not visible to remote sensing instruments, were mapped in Yosemite National Park using the random forests decision tree algorithm and climatic, topographic, remotely sensed, and fire history variables. Combining the disparate data sources served to improve classification accuracies. The models were inverted to produce maps of fuel models and fuel amounts, and these showed that fire fuel amounts are highest in the low elevation forests that have been most affected by fire suppression impacting the natural fire regime. Wildland fires in chaparral commonly burn in late summer or fall when LFM is near its annual low, however, the Jesusita Fire burned in early May of 2009, when LFM was still relatively high. The HFire fire spread model was used to simulate the growth of the Jesusita Fire using LFM maps derived from imagery acquired at the time of the fire and imagery acquired in late August to determine how much different the fire would have been if it had occurred later in the year. Simulated fires were 1.5 times larger

  15. en Baja California

    Directory of Open Access Journals (Sweden)

    Elmyra Ybañez Zepeda

    2007-01-01

    Full Text Available In the future, the population of 60 years old or older will increase in absolute and relative numbers at a very rapid pace in Mexico. Using data from Censo general de población y vivienda 2000, Encuesta sobre migración en la frontera norte de México and Consejo Nacional de Población (Conapo, the purpose of this article is twofold: first of all, to analyze the aging process in the municipalities of Tijuana and Mexicali, located in the state of Baja California, which has a very low proportion of the eldest; and second of all, to examine the role of migration in this process. Tijuana has a younger population which is aging slowly due to a very intense immigration of young workers and potential parents. Mexicali, on the other hand, has a high percentage of a native population that is aging unrelentingly, and it also has a lower flow of immigrants who are older, and includes a high concentration of persons who had previously resided in the United States.

  16. Leishmaniasis in beige mice.

    OpenAIRE

    Kirkpatrick, C E; Farrell, J P

    1982-01-01

    The courses of two protozoal diseases, cutaneous and visceral leishmaniasis, were examined in three groups of C57BL/6J mice. One group of mice was homozygous recessive for the beige gene (bg/bg). Beige mice are the genetic homologue of the human Chédiak-Higashi syndrome and, among other defects, are profoundly deficient in natural killer cell activity. Wild-type (+/+) mice, which respond to experimental cutaneous or visceral leishmaniasis by eventually eliminating their parasites, and heteroz...

  17. The MICE luminosity monitor

    OpenAIRE

    Dobbs, A.; Forrest, D; F.J.P. Soler

    2013-01-01

    The MICE experiment will provide the first measurement of ionisation cooling, a technique suitable for reducing the transverse emittance of a tertiary muon beam in a future neutrino factory accelerator facility. MICE is presently in the final stages of commissioning its beam line. The MICE luminosity monitor has proved an invaluable tool throughout this process, providing independent measurements of particle rate from the MICE target, normalisation for beam line detectors and verification of ...

  18. Southern California Adjoint Source Inversions

    Science.gov (United States)

    Tromp, J.; Kim, Y.

    2007-12-01

    Southern California Centroid-Moment Tensor (CMT) solutions with 9 components (6 moment tensor elements, latitude, longitude, and depth) are sought to minimize a misfit function computed from waveform differences. The gradient of a misfit function is obtained based upon two numerical simulations for each earthquake: one forward calculation for the southern California model, and an adjoint calculation that uses time-reversed signals at the receivers. Conjugate gradient and square-root variable metric methods are used to iteratively improve the earthquake source model while reducing the misfit function. The square-root variable metric algorithm has the advantage of providing a direct approximation to the posterior covariance operator. We test the inversion procedure by perturbing each component of the CMT solution, and see how the algorithm converges. Finally, we demonstrate full inversion capabilities using data for real Southern California earthquakes.

  19. Teale Urband and rural areas of California

    Data.gov (United States)

    California Department of Resources — California Spatial Information System (CaSIL) is a project designed to improve access to geo-spatial and geo-spatial related data information throughout the state...

  20. Teale California Office of Emergency Services

    Data.gov (United States)

    California Department of Resources — California Spatial Information System (CaSIL) is a project designed to improve access to geo-spatial and geo-spatial related data information throughout the state...

  1. Licensing and Certification District Offices, California

    Data.gov (United States)

    U.S. Department of Health & Human Services — This data contains a list of California Licensing and Certification District Offices. The California Department of Public Health, Center for Health Care Quality,...

  2. California Least Tern Breeding Survey 1992 Season

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 1992, approximately 2,106 pairs of the endangered California Least Tern (Sterna antillarum browni) nested at 38 sites along the coast of California, from the San...

  3. California Least Tern Breeding Survey 1994 Season

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 1994, a minimum of approximately 2,792 pairs of the endangered California least tern (Sterna antillarum browni) nested at 36 sites along the coast of California....

  4. California Least Tern Breeding Survey 1996 Season

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 1996, 3330-3392 pairs of the endangered California least tern (Sterna antillarum browni) nested at 35 sites along the coast of California. This 29% increase in...

  5. California Geological Survey Geologic Map Index

    Data.gov (United States)

    California Department of Resources — All the individual maps from the Geologic Atlas of California and the Regional Geologic map series have been georeferenced for display in a GIS (and viewable online...

  6. California Hydrogen Infrastructure Project

    Energy Technology Data Exchange (ETDEWEB)

    Heydorn, Edward C

    2013-03-12

    Air Products and Chemicals, Inc. has completed a comprehensive, multiyear project to demonstrate a hydrogen infrastructure in California. The specific primary objective of the project was to demonstrate a model of a real-world retail hydrogen infrastructure and acquire sufficient data within the project to assess the feasibility of achieving the nation's hydrogen infrastructure goals. The project helped to advance hydrogen station technology, including the vehicle-to-station fueling interface, through consumer experiences and feedback. By encompassing a variety of fuel cell vehicles, customer profiles and fueling experiences, this project was able to obtain a complete portrait of real market needs. The project also opened its stations to other qualified vehicle providers at the appropriate time to promote widespread use and gain even broader public understanding of a hydrogen infrastructure. The project engaged major energy companies to provide a fueling experience similar to traditional gasoline station sites to foster public acceptance of hydrogen. Work over the course of the project was focused in multiple areas. With respect to the equipment needed, technical design specifications (including both safety and operational considerations) were written, reviewed, and finalized. After finalizing individual equipment designs, complete station designs were started including process flow diagrams and systems safety reviews. Material quotes were obtained, and in some cases, depending on the project status and the lead time, equipment was placed on order and fabrication began. Consideration was given for expected vehicle usage and station capacity, standard features needed, and the ability to upgrade the station at a later date. In parallel with work on the equipment, discussions were started with various vehicle manufacturers to identify vehicle demand (short- and long-term needs). Discussions included identifying potential areas most suited for hydrogen fueling

  7. Tobacco Use in California, 1990

    OpenAIRE

    University of California, San Diego; California Department of Health Services

    1991-01-01

    Summary This report presents data on a partial sample of a survey of cigarette smoking behaviors and attitudes among Californians conducted during the summer of 1990. The prevalence of current smoking among adults in California is 21.2%, with males (23.8%) smoking more than females(18.8%). This represents a sharp decline in smoking following the increase in the tobacco excise tax and implementation of a comprehensive tobacco control program by the State of California,and is on track ...

  8. California`s schedule coordinator : market maker with advantage?

    Energy Technology Data Exchange (ETDEWEB)

    Woychik, E.C. [Strategy Integration, Oakland, CA (United States)

    1998-07-01

    The new role for Schedule Coordinators (SCs) in California`s newly restructured electric power industry was discussed. The SC concept and its complex roles in the physical (as opposed to financial) markets for power was described. The role of the SC is to negotiate generator and load changes with its client participants. The SC can reflect any contracted-for arrangement in its next set of schedules to the ISO. The SC is free to negotiate any bilateral contract with or between client participants and can combine any or all contracts between market participants. California`s Power Exchange (PX) is also considered a SC, but compared to other SCs, it has restricted capabilities. The PX is a market maker that accepts day-ahead and hour-ahead energy bids (supply and demand) and loads. If market power abuse becomes evident, FERC can re-regulate the ISO and PX. The implications of this experiment for electricity reforms are enormous. In the past the concern was on concentration of generation ownership. In the future competitors may have to focus on concentration of generation control through SCs. The industry will have to be vigilant to ensure that the experiment leads to dynamic rivalry of companies and not to the pursuit and capture of monopoly powers.

  9. Lecturas de Baja California (Readings from Baja California).

    Science.gov (United States)

    Munoz, Gabriel Trujillo, Ed.

    This anthology/textbook is part of a Mexican series of instructional materials designed for Spanish speaking adults who are in the process of becoming literate or have recently become literate in their native language. This document presents a collection of works from important writers directed to the population of Baja California, especially to…

  10. Fees at California's Public Colleges and Universities

    Science.gov (United States)

    Fuller, Ryan

    2009-01-01

    Fees at California's public colleges and universities have increased in the past two decades, but are still lower than fees at comparable institutions in other states. Fees for full-time undergraduate students at the University of California were $8,027 in 2008-09 and fees at California State University were $3,849. Fees are likely to rise for the…

  11. Transhumant Ranchers in California

    Science.gov (United States)

    Sulak, A.; Forero, L.; Huntsinger, L.

    2009-04-01

    There is a strong link between some of the richest, most productive lands of the western United States, including California's oak woodlands, and the traditional "transhumance" of ranchers using public ranges. Oak woodland ranchers with government grazing leases report that about half of their income stems from using government -owned montane ranges. For many, loss of these leases reduces their ranch productive capacity to a level insufficient for sustainability, augmenting the sale of ranch lands for development. Many thousands of hectares of oak woodlands are linked to the fate of government leases in this way, and this linkage limits the opportunities for conservation of oak woodlands as "working landscapes" via conservation easements. This type of conservation is the fastest growing type in California today. The first case study shows that over the past 100 years there has been a reduction in access to the natural resources needed for transhumance from three sources: competition from use of the pastures for recreation and nature preservation, management practices that have brought about change in the character of the natural resources themselves, and urban sprawl. Ranchers are leasing other properties, purchasing feed, and transporting animals to other regions to compensate. Most had increased their privately leased land over the previous five years. Though they desire to stay on their ranches, transhumant ranching is becoming increasingly difficult because of land use changes on both public and private lands and a third of ranchers believe that they may need to sell the property for development if they lose their summer permits. There are many "line camps" on Forest Service range—cabins that families or workers would stay in during the summer to tend the cattle. However, the need to support the ranch with work in town limits the ability of the household to participate in transhumance or even travel into the mountains to check on the animals. For ranching to

  12. The California Basic Skills Initiative

    Science.gov (United States)

    Illowsky, Barbara

    2008-01-01

    This article describes the evolution and implementation of the California Basic Skills Initiative (CA BSI), a statewide effort to address ongoing basic skills and ESL needs of community college students and of all campus faculty, administrators, and staff who support these students. CA BSI strategies include assisting every college in assessing…

  13. Franklin Fenenga and California Archaeology

    OpenAIRE

    Wallace, William J

    1999-01-01

    Franklin Fenenga died suddenly on April 7, 1994, of pneumonia. Shortly before, ha had learned that he had inoperable lung cancer and only a relatively short time to live. His death ended a long and noteworthy career of research into California's archaeological past.

  14. Lyme Disease in Northern California

    OpenAIRE

    Campagna, Joan; Lavoie, Paul E.; Birnbaum, Neal S.; Furman, Deane P.

    1983-01-01

    Lyme disease is a recently described clinical entity with cutaneous, neurologic, articular and cardiac manifestations. Since the original description of the disease in 1977, more than 500 cases have been reported. Although the vast majority of patients have been from the area near Lyme, Connecticut, we have seen four patients from northern California with various aspects of Lyme disease.

  15. California Amusement Rides and Liability

    Science.gov (United States)

    Epstein, Adam

    2005-01-01

    Twenty-three-year-old Cristina Moreno traveled from Spain to California for her honeymoon in 2000. As part of her visit, she rode the Indiana Jones amusement ride at Disneyland with her new husband. On June 25, 2000, she suffered a brain injury, and she eventually died on September 1, 2000, as a result of injuries allegedly sustained while riding…

  16. Dismantling College Opportunity in California

    OpenAIRE

    The Civil Rights Project/ Proyecto Derechos Civiles

    2011-01-01

    These studies released today call attention to the fact that cuts to higher education impact students, their families, CSU faculty, and staff well beyond the classroom. Reduction in access, retention, and increase in cost are disproportionately impacting traditionally underrepresented students, and are being felt within their personal lives. Related Documents Dismantling College Opportunity in California These three reports constitute Part Four of The ...

  17. California Endangered Species Resource Guide.

    Science.gov (United States)

    California State Dept. of Education, Los Angeles.

    This document was developed in response to California Senate Bill No. 885, "The Endangered Species Education Project," that called for a statewide program in which schools adopt a local endangered species, research past and current efforts to preserve the species' habitat, develop and implement an action plan to educate the community about the…

  18. MICE IN CHINA

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The MICE (Meetings, Incentives, Conventions, and Exhibitions) industry has exploded worldwide over the past decade. The benefits brought by meetings, incentives, conventions, and exhibitions are also benefiting other sectors involved in MICE events, including hotels, travel, and retail. Industry analysts estimate that the income from the global MICE industry will soon exceed USD 220 billion, and is expected to increase by 8-10% each year.

  19. Australian growth: a California perspective

    OpenAIRE

    Ian W. McLean; Taylor, Alan M.

    2001-01-01

    Examination of special cases assists understanding of the mechanics of long-run economic growth more generally. Australia and California are two economies having the rare distinction of achieving 150 years of sustained high and rising living standards for rapidly expanding populations. They are suitable comparators since in some respects they are quite similar, especially in their initial conditions in the mid-nineteenth century, their legal and cultural inheritances, and with respect to some...

  20. Turkey vulture and California condor

    Science.gov (United States)

    Pattee, O.H.; Wilbur, S.R.

    1989-01-01

    Populations of turkey vultures in the western states appear stable, with no evidence of recent significant changes in distribution. Turkey vultures occupy a variety of habitats, nest in diverse situations and utilize a wide variety of carrion. Consequently, no particular limiting factor is likely to have a major effect on the total population. California condor numbers, in contrast, have continued to decline. With the capture of the last wild bird in 1987, the species has been extirpated from the wild. Reestablishment will depend on production and introduction of captive-reared birds, hopefully within the next 10 years. In the 18th century, condors inhabited areas along the Pacific coast from British Columbia to Baja California. Since 1950, the range has been restricted to a six county area adjacent to the southern San Joaquin Valley of California. Within this area, there appears to be no shortage of suitable nest sites; all recently used nest sites are within federally-controlled lands. Suitable foraging grounds have continued to diminish and are now largely limited to private rangelands and some Bureau of Land Management rangelands within the foothills of the San Joaquin Valley. Only these areas continue to supply the large mammal carcasses that the California condor needs for survival. The habitat of the condor is subject to a variety of land use practices and development pressures. Excessive mortality, coupled with low reproductive potential, continues to threaten the recovery of the species. Development of management practices to reduce mortality, particularly those that are contaminant-related, and of a preserve design to insure adequate habitat for the reintroduced population are still necessary for eventual recovery of the species.

  1. Is California's future hydraulically sustainable?

    OpenAIRE

    Richard E. Howitt

    2011-01-01

    The term “hydraulic society” describes the ancient cities and social systems that relied on irrigated agriculture, such as Egypt's Nile Valley. For 5,000 years, the annual cycle of floods replenished the Nile region's soil and nutrients, eliminating the need for complex canal systems such as those found in the Sumerian and Mesopotamian regions. California is the first hydraulic society that is rapidly developing into a postindustrial economy; this change will require the partial re-allocation...

  2. THE CALIFORNIA MEDICAL MALPRACTICE PICTURE.

    Science.gov (United States)

    RUBSAMEN, D S

    1963-11-01

    The California physician's steadily increasing risk of legal liability poses a basic question: Will he ultimately wind up a guarantor of results, carrying a great burden of malpractice insurance in order to pay for every untoward result of medical treatment? This alarming prospect is the result of many years of judicial (and therefore lay) speculation on the legal significance of the injury which brings the patient into court. Does it look as though this injury probably is associated with medical negligence? If so, let the doctor explain. And the explanation must be very complete. The legal instrument which thus reverses the traditional requirements of proof, permitting the patient-plaintiff to remain silent while the doctor-defendant must exculpate himself, is an evidentiary doctrine called res ipsa loquitur-the thing speaks for itself. The application of the doctrine relieves the patient-plaintiff of the necessity of producing an expert witness to point the finger and say, "The medical conduct that produced this injury was sub-standard." The increased use of the doctrine reflects a judicial conviction that in many parts of California physicians refuse to testify for the patient-plaintiff regardless of the merit to his case.A recent California Supreme Court decision suggests that the Court is not unaware of the adverse social consequences implicit in the irrational expansion of the physician's risk of legal liability. But a reversal of this trend would seem to be contingent on positive conduct from the medical profession in California-conduct demonstrating that no meritorious patient-plaintiff will fail in his malpractice lawsuit for lack of an expert medical witness. PMID:14081771

  3. A Family of Mice

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ 一、故事内容 There is a family of mice in my house. They are father mouse, mother mouse and baby mouse. Baby mouse likes dancing. He is very cute. Father mouse likes watching TV. He likes the sports on TV best. These three mice are clever.

  4. Of mice and men

    CERN Multimedia

    1973-01-01

    At the end of March , sixty mice were irradiated at the synchro-cyclotron in the course of an experimental programme studying radiation effects on mice and plants (Vicia faba bean roots) being carried out by the CERN Health Physics Group.

  5. Generation of Transgenic Mice

    OpenAIRE

    Cho, Andrew; Haruyama, Naoto; Kulkarni, Ashok B.

    2009-01-01

    This unit describes detailed step-by-step protocols, reagents, and equipment required for successful generation of transgenic mice using pronuclear injection. The experimental methods and practical tips given here will help guide beginners in understanding what is required and what to avoid in these standard protocols for efficiently generating transgenic mice.

  6. Global climate change and California

    International Nuclear Information System (INIS)

    In the fall of 1988 the University of California organized a new public-service initiative on global climate change in response to inquiries and requests from members of Congress and the Department of Energy (DOE). This new systemwide initiative involved all of the University of California campuses and the University's three national laboratories at Berkeley, Los Alamos, and Livermore. The goal of this Greenhouse Initiative was to focus the multidisciplinary resources of the UC campuses and the team-oriented research capabilities of the laboratories on the prospect of global warming and its associated effects on the planet and its nations. In consultation with the DOE, the organizers proposed a series of workshops to focus University of California research resources on the issue of global warming, to contribute to the congressionally mandated DOE studies on options for the US to reduce carbon dioxide emissions by 20% by the year 2000, and to begin building a long-term research base contributing to an improved understanding of global change in all of its complexity and diverse discipline implications. This volume contains papers from the first of these workshops. Individual papers are processed separately for inclusion in the appropriate data bases

  7. The MICE Online Systems

    CERN Document Server

    CERN. Geneva

    2012-01-01

    The Muon Ionization Cooling Experiment (MICE) is designed to test transverse cooling of a muon beam, demonstrating an important step along the path toward creating future high intensity muon beam facilities. Protons in the ISIS synchrotron impact a titanium target, producing pions which decay into muons that propagate through the beam line to the MICE cooling channel. Along the beam line, particle identification (PID) detectors, scintillating fiber tracking detectors, and beam diagnostic tools identify and measure individual muons moving through the cooling channel. The MICE Online Systems encompass all tools; including hardware, software, and documentation, within the MLCR (MICE Local Control Room) that allow the experiment to efficiently record high quality data. Controls and Monitoring (C&M), Data Acquisition (DAQ), Online Monitoring and Reconstruction, Data Transfer, and Networking all fall under the Online Systems umbrella. C&M controls all MICE systems including the target, conventional an...

  8. California commercial building energy benchmarking

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, Satkartar; Piette, Mary Ann

    2003-07-01

    Building energy benchmarking is the comparison of whole-building energy use relative to a set of similar buildings. It provides a useful starting point for individual energy audits and for targeting buildings for energy-saving measures in multiple-site audits. Benchmarking is of interest and practical use to a number of groups. Energy service companies and performance contractors communicate energy savings potential with ''typical'' and ''best-practice'' benchmarks while control companies and utilities can provide direct tracking of energy use and combine data from multiple buildings. Benchmarking is also useful in the design stage of a new building or retrofit to determine if a design is relatively efficient. Energy managers and building owners have an ongoing interest in comparing energy performance to others. Large corporations, schools, and government agencies with numerous facilities also use benchmarking methods to compare their buildings to each other. The primary goal of Task 2.1.1 Web-based Benchmarking was the development of a web-based benchmarking tool, dubbed Cal-Arch, for benchmarking energy use in California commercial buildings. While there were several other benchmarking tools available to California consumers prior to the development of Cal-Arch, there were none that were based solely on California data. Most available benchmarking information, including the Energy Star performance rating, were developed using DOE's Commercial Building Energy Consumption Survey (CBECS), which does not provide state-level data. Each database and tool has advantages as well as limitations, such as the number of buildings and the coverage by type, climate regions and end uses. There is considerable commercial interest in benchmarking because it provides an inexpensive method of screening buildings for tune-ups and retrofits. However, private companies who collect and manage consumption data are concerned that the

  9. California Prune Board's Promotion Program: An Evaluation.

    OpenAIRE

    Chalfant, James A.; Crespi, John M. M.; Sexton, Richard J.; Venner, Raymond J.

    1998-01-01

    California is the world leader in prune production, accounting for about 99 percent of U.S. production and 70 percent of the world's supply. The industry, through the California Prune Board (CPB) and its various packers, especially Sunsweet Growers, the largest marketer of California prunes, has invested substantially in the promotion of prunes to consumers. This study analyzes the effectiveness of these expenditures in increasing consumer demand for prunes and, thereby, in raising industry r...

  10. Southern California Channel Islands Bibliography, through 1992

    OpenAIRE

    Channel Islands National Marine Sanctuary

    1992-01-01

    The Southern California Channel Islands Bibliography, through 1992, comprises 4035 references to the scientific literature on Southern California's Channel Islands. The Bibliography was compiled by the Channel Islands National Marine Sanctuary and is presented here in a February 1993 version. The Santa Barbara Museum of Natural History presents a California Channel Islands Bibliography on its website. It has more recent references and overlaps considerably with this bibliography. How...

  11. California's experience with alternative fuel vehicles

    International Nuclear Information System (INIS)

    California is often referred to as a nation-state, and in many aspects fits that description. The state represents the seventh largest economy in the world. Most of California does not have to worry about fuel to heat homes in the winter. What we do worry about is fuel for our motor vehicles, approximately 24 million of them. In fact, California accounts for ten percent of new vehicle sales in the United States each year, much of it used in the transportation sector. The state is the third largest consumer of gasoline in the world, only exceeded by the United States as a whole and the former Soviet Union. California is also a leader in air pollution. Of the nine worst ozone areas in the country cited in the 1990 Clean Air Act Amendments, two areas the Los Angeles Basin and San Diego are located in California. Five of California's cities made the top 20 smoggiest cities in the United States. In reality, all of California's major metropolitan areas have air quality problems. This paper will discuss the beginnings of California's investigations of alternative fuels use in vehicles; the results of the state's demonstration programs; and future plans to improve California's air quality and energy security in the mobile sector

  12. California's Accountability System and the API. Expert Report. Submitted for: Eliezer Williams vs. State of California.

    Science.gov (United States)

    Russell, Michael

    This paper was presented as expert testimony in the Williams vs. State of California class action lawsuit. That case, filed on behalf of California public schoolchildren, charged the State with denying thousands of students the basic tools for a sound education. This paper addresses whether California's current output-based accountability system…

  13. 78 FR 77447 - California Wind Energy Association, First Solar, Inc. v. California Independent System Operator...

    Science.gov (United States)

    2013-12-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission California Wind Energy Association, First Solar, Inc. v. California... Practice and Procedure, 18 CFR 385.206 (2013), California Wind Energy Association and First Solar,...

  14. LiDAR data for the Delta Area of California

    Data.gov (United States)

    California Department of Resources — LiDAR data for the Delta Area of California from the California Department of Water Resources. Bare earth grids from LiDAR.This data is in ESRI Grid format with 2...

  15. California's 2002 Clean Water Act Section 303(d) - Impaired Waterbodies

    Data.gov (United States)

    California Department of Resources — This dataset contains California's 2002 Clean Water Act Section 303(d) list which is submitted by the California State Water Resources Control Board. The layer has...

  16. Measures in Mice

    OpenAIRE

    Schlutzenberg, Farmer

    2013-01-01

    This thesis analyses extenders in fine structural mice. Kunen showed that in the inner model for one measurable cardinal, there is a unique measure. This result is generalized, in various ways, to mice below a superstrong cardinal. The analysis is then used to show that certain tame mice satisfy $V=\\mathsf{HOD}$. In particular, the approach proides a new proof of this result for the inner model $M_n$ for $n$ Woodin cardinals. It is also shown that in $M_n$, all homogeneously Suslin sets of re...

  17. The carbon budget of California

    International Nuclear Information System (INIS)

    The carbon budget of a region can be defined as the sum of annual fluxes of carbon dioxide (CO2) and methane (CH4) greenhouse gases (GHGs) into and out of the regional surface coverage area. According to the state government's recent inventory, California's carbon budget is presently dominated by 115 MMTCE per year in fossil fuel emissions of CO2 (>85% of total annual GHG emissions) to meet energy and transportation requirements. Other notable (non-ecosystem) sources of carbon GHG emissions in 2004 were from cement- and lime-making industries (7%), livestock-based agriculture (5%), and waste treatment activities (2%). The NASA-CASA (Carnegie Ames Stanford Approach) simulation model based on satellite observations of monthly vegetation cover (including those from the Moderate Resolution Imaging Spectroradiometer, MODIS) was used to estimate net ecosystem fluxes and vegetation biomass production over the period 1990-2004. California's annual NPP for all ecosystems in the early 2000s (estimated by CASA at 120 MMTCE per year) was roughly equivalent to its annual fossil fuel emission rates for carbon. However, since natural ecosystems can accumulate only a small fraction of this annual NPP total in long-term storage pools, the net ecosystem sink flux for atmospheric carbon across the state was estimated at a maximum rate of about 24 MMTCE per year under favorable precipitation conditions. Under less favorable precipitation conditions, such as those experienced during the early 1990s, ecosystems statewide were estimated to have lost nearly 15 MMTCE per year to the atmosphere. Considering the large amounts of carbon estimated by CASA to be stored in forests, shrublands, and rangelands across the state, the importance of protection of the natural NPP capacity of California ecosystems cannot be overemphasized.

  18. Dubious battle in California Dubious battle in California

    Directory of Open Access Journals (Sweden)

    John Steinbeck

    2008-04-01

    Full Text Available In sixty years a complete revolution has taken place in California agriculture. Once its principal products were hay and cattle. Today fruits and vegetables are its most profitable crops. With the change in the nature of farming there has come a parallel change in the nature and amount of the labor necessary to carry it on. Truck gardens, while they give a heavy yield per acre, require much more labor and equipment than the raising of hay and livestock. At the same time these crops are seasonal, which means that they are largely handled by migratory workers. Along with the intensification of farming made necessary by truck gardening has come another important development. In sixty years a complete revolution has taken place in California agriculture. Once its principal products were hay and cattle. Today fruits and vegetables are its most profitable crops. With the change in the nature of farming there has come a parallel change in the nature and amount of the labor necessary to carry it on. Truck gardens, while they give a heavy yield per acre, require much more labor and equipment than the raising of hay and livestock. At the same time these crops are seasonal, which means that they are largely handled by migratory workers. Along with the intensification of farming made necessary by truck gardening has come another important development.

  19. AGUA TIBIA PRIMITIVE AREA, CALIFORNIA.

    Science.gov (United States)

    Irwin, William P.; Thurber, Horace K.

    1984-01-01

    The Agua Tibia Primitive Area in southwestern California is underlain by igneous and metamorphic rocks that are siilar to those widely exposed throughout much of the Peninsular Ranges. To detect the presence of any concealed mineral deposits, samples of stream sediments were collected along the various creeks that head in the mountain. As an additional aid in evaluating the mineral potential, an aeromagnetic survey was made and interpreted. A search for records of past or existing mining claims within the primitive area was made but none was found. Evidence of deposits of metallic or nonmetallic minerals was not seen during the study.

  20. Recent mortality patterns in California.

    Science.gov (United States)

    O'Brien, K F; Zaharia, E S

    1998-10-01

    Mortality among people with developmental disabilities was reviewed using recent data obtained from the California Department of Developmental Services. The time interval for this report was 1991-1995. We defined two study cohorts: one beginning in January 1991 and a second in April 1993. The latter period represented the years of implementation of the Coffelt settlement. Our primary interest was in the Coffelt period cohort. Statistically significant association with increased rates of mortality was found for community residence. A trend of declining mortality was noted for the community facilities from 1991-1995, but not for the developmental centers. PMID:9803127

  1. CACTUS SPRING ROADLESS AREA, CALIFORNIA.

    Science.gov (United States)

    Matti, Jonathan C.; Kuizon, Lucia

    1984-01-01

    Geologic, geochemical, and geophysical studies together with a review of historic mining and prospecting activities indicate that the Cactus Spring Roadless Area in California has little promise for the occurrence of mineral or energy resources. Marble bodies occur in the northern part of the roadless area and are possible resources for building stone, crushed and quarried aggregate, and lime and magnesium for Portland cement and industrial applications. It is recommended that the terrane of marble be mapped and sampled carefully in order to evaluate the quantity and quality of the carbonate resources.

  2. AVIRIS spectra of California wetlands

    Science.gov (United States)

    Gross, Michael F.; Ustin, Susan L.; Klemas, Vytautas

    1988-01-01

    Spectral data gathered by the AVIRIS from wetlands in the Suisun Bay area of California on 13 October 1987 were analyzed. Spectra representing stands of numerous vegetation types (including Sesuvium verrucosum, Scirpus acutus and Scirpus californicus, Xanthium strumarium, Cynadon dactylon, and Distichlis spicata) and soil were isolated. Despite some defects in the data, it was possible to detect vegetation features such as differences in the location of the chlorophyll red absorption maximum. Also, differences in cover type spectra were evident in other spectral regions. It was not possible to determine if the observed features represent noise, variability in canopy architecture, or chemical constituents of leaves.

  3. Mice Status Report: September 2010

    OpenAIRE

    Blondel, Alain; Hanson, G.

    2010-01-01

    This report is prepared for the MICE Project Board meeting of September 2010. It constitutes an update of the reports produced for the MICE Funding Agency Committee in December 20081, October 20092 and April 20103 and concentrates on the progress made since. The design of the MICE experiment can be found in the MICE proposal

  4. California Red-Legged Frog Range - CWHR [ds587

    Data.gov (United States)

    California Department of Resources — Vector datasets of CWHR range maps are one component of California Wildlife Habitat Relationships (CWHR), a comprehensive information system and predictive model...

  5. Sonoma Ecology Center Northern California Arundo Distribution Data

    Data.gov (United States)

    California Department of Resources — The Arundo Distribution layer is a compilation of Arundo donax observations in northern and central California, obtained from numerous sources, including Arundo...

  6. Exploring MICE Potential

    Institute of Scientific and Technical Information of China (English)

    LIU BO

    2006-01-01

    @@ With commerce and entertainment increasingly intertwined and the Chinese economy becoming more internationally integrated, Meetings,Incentives, Conference and Exhibitions (MICE) travel, is regarded by many travel agencies as one of the most potentially profitable tourism trends of the future.

  7. MICE Particle Identification Systems

    OpenAIRE

    Sanders, D. A.

    2009-01-01

    The international Muon Ionization Cooling Experiment (MICE) is being built, at the Rutherford Appleton Laboratory (RAL), to demonstrate the feasibility of ionization cooling of muon beams. This is one of the major technological steps needed in the development of a muon collider and a neutrino factory based on muon decays in a storage ring. MICE will use particle detectors to measure the cooling effect with high precision, achieving a precision on the measurement of emittance of 0.1% or better...

  8. Case study : The California Digital Library

    OpenAIRE

    Ober, John

    2002-01-01

    The California Digital Library was founded in 1997 as a digital “co-library” of the 10 Universities of California campuses. Responses to crisis in scholarly communication and the opportunity presented by digital technologies and the Web. Charged to create a comprehensive system for the management of digital scholarly information.

  9. Supporting Continuous Improvement in California's Education System

    Science.gov (United States)

    Darling-Hammond, Linda; Plank, David N.

    2015-01-01

    California's new accountability system originated in the radical decentralization of power and authority from Sacramento to local schools and their communities brought about by the Legislature's adoption of the Local Control Funding Formula (LCFF) in 2013. Under California's previous accountability policies and the federal "No Child Left…

  10. California Community Colleges: Vital to the Economy

    Science.gov (United States)

    California Community Colleges, Chancellor's Office, 2014

    2014-01-01

    The California Community Colleges play an important role in boosting the state's economy by serving more than 2.3 million students a year. In fact, one out of three community college students in the U.S. is enrolled in a California community college, making it the nation's largest system of higher education. Their 112 colleges provide students…

  11. Transgenic mice: beyond the knockout

    OpenAIRE

    Miller, R. Lance

    2010-01-01

    Transgenic mice have had a tremendous impact on biomedical research. Most researchers are familiar with transgenic mice that carry Cre recombinase (Cre) and how they are used to create conditional knockouts. However, some researchers are less familiar with many of the other types of transgenic mice and their applications. For example, transgenic mice can be used to study biochemical and molecular pathways in primary cultures and cell suspensions derived from transgenic mice, cell-cell interac...

  12. Transgenic mice susceptible to poliovirus.

    OpenAIRE

    S. Koike; Taya, C; Kurata, T; Abe, S.; Ise, I; Yonekawa, H; Nomoto, A

    1991-01-01

    Poliovirus-sensitive transgenic mice were produced by introducing the human gene encoding cellular receptors for poliovirus into the mouse genome. Expression of the receptor mRNAs in tissues of the transgenic mice was analyzed by using RNA blot hybridization and the polymerase chain reaction. The human gene is expressed in many tissues of the transgenic mice just as in tissues of humans. The transgenic mice are susceptible to all three poliovirus serotypes, and the mice inoculated with poliov...

  13. Illuminating Northern California's Active Faults

    Science.gov (United States)

    Prentice, Carol S.; Crosby, Christopher J.; Whitehill, Caroline S.; Arrowsmith, J. Ramón; Furlong, Kevin P.; Phillips, David A.

    2009-02-01

    Newly acquired light detection and ranging (lidar) topographic data provide a powerful community resource for the study of landforms associated with the plate boundary faults of northern California (Figure 1). In the spring of 2007, GeoEarthScope, a component of the EarthScope Facility construction project funded by the U.S. National Science Foundation, acquired approximately 2000 square kilometers of airborne lidar topographic data along major active fault zones of northern California. These data are now freely available in point cloud (x, y, z coordinate data for every laser return), digital elevation model (DEM), and KMZ (zipped Keyhole Markup Language, for use in Google Earth™ and other similar software) formats through the GEON OpenTopography Portal (http://www.OpenTopography.org/data). Importantly, vegetation can be digitally removed from lidar data, producing high-resolution images (0.5- or 1.0-meter DEMs) of the ground surface beneath forested regions that reveal landforms typically obscured by vegetation canopy (Figure 2).

  14. California sea lions (Zalophus californianus californianus) have lower chlorinated hydrocarbon contents in northern Baja California, Mexico, than in California, USA

    Energy Technology Data Exchange (ETDEWEB)

    Del Toro, Ligeia [Universidad Autonoma de Baja California (UABC), Facultad de Ciencias Marinas, Ensenada, Baja California (Mexico); Investigacion y Conservacion de Mamiferos Marinos de Ensenada, A.C., Placido Mata 2309 Depto. D-5, Condominio Las Fincas, Ensenada, Baja California 22810 (Mexico); Heckel, Gisela [Investigacion y Conservacion de Mamiferos Marinos de Ensenada, A.C., Placido Mata 2309 Depto. D-5, Condominio Las Fincas, Ensenada, Baja California 22810 (Mexico) and Centro de Investigacion Cientifica y de Educacion Superior de Ensenada, B.C. Km 107 Carretera Tijuana-Ensenada, Ensenada, Baja California 22860 (Mexico)]. E-mail: gheckel@cicese.mx; Camacho-Ibar, Victor F. [Instituto de Investigaciones Oceanologicas, UABC, Apdo. Postal 453, Ensenada, Baja California 22860 (Mexico); Schramm, Yolanda [Universidad Autonoma de Baja California (UABC), Facultad de Ciencias Marinas, Ensenada, Baja California (Mexico); Investigacion y Conservacion de Mamiferos Marinos de Ensenada, A.C., Placido Mata 2309 Depto. D-5, Condominio Las Fincas, Ensenada, Baja California 22810 (Mexico)

    2006-07-15

    Chlorinated hydrocarbons (CHs) were determined in blubber samples of 18 California sea lions (Zalophus californianus californianus) that stranded dead along Todos Santos Bay, Ensenada, Baja California, Mexico, January 2000-November 2001. {sigma}DDTs were the dominant group (geometric mean 3.8 {mu}g/g lipid weight), followed by polychlorinated biphenyls ({sigma}PCBs, 2.96 {mu}g/g), chlordanes (0.12 {mu}g/g) and hexachlorocyclohexanes (0.06 {mu}g/g). The {sigma}DDTs/{sigma}PCBs ratio was 1.3. We found CH levels more than one order of magnitude lower than those reported for California sea lion samples collected along the California coast, USA, during the same period as our study. This sharp north-south gradient suggests that Z. californianus stranded in Ensenada (most of them males) would probably have foraged during the summer near rookeries 500-1000 km south of Ensenada and the rest of the year migrate northwards, foraging along the Baja California peninsula, including Ensenada, and probably farther north. - Results suggest that sea lion prey must also have lower hydrocarbons in Baja California than in California in the USA.

  15. California sea lions (Zalophus californianus californianus) have lower chlorinated hydrocarbon contents in northern Baja California, Mexico, than in California, USA

    International Nuclear Information System (INIS)

    Chlorinated hydrocarbons (CHs) were determined in blubber samples of 18 California sea lions (Zalophus californianus californianus) that stranded dead along Todos Santos Bay, Ensenada, Baja California, Mexico, January 2000-November 2001. ΣDDTs were the dominant group (geometric mean 3.8 μg/g lipid weight), followed by polychlorinated biphenyls (ΣPCBs, 2.96 μg/g), chlordanes (0.12 μg/g) and hexachlorocyclohexanes (0.06 μg/g). The ΣDDTs/ΣPCBs ratio was 1.3. We found CH levels more than one order of magnitude lower than those reported for California sea lion samples collected along the California coast, USA, during the same period as our study. This sharp north-south gradient suggests that Z. californianus stranded in Ensenada (most of them males) would probably have foraged during the summer near rookeries 500-1000 km south of Ensenada and the rest of the year migrate northwards, foraging along the Baja California peninsula, including Ensenada, and probably farther north. - Results suggest that sea lion prey must also have lower hydrocarbons in Baja California than in California in the USA

  16. Energy Efficiency Roadmap for Petroleum Refineries in California

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-04-01

    Through the California State IOF initiative, the California Energy Commission PIER Program developed a petroleum refining roadmap to identify energy issues and priorities unique to the refining industry in California and create a plan for future R&D that could help California refineries implement energy efficient technologies.

  17. The Carbon Budget of California

    Science.gov (United States)

    Potter, C. S.

    2009-12-01

    The carbon budget of a region can be defined as the sum of annual fluxes of carbon dioxide and methane greenhouse gases (GHGs) into and out of the regional surface coverage area. According to the state government’s recent inventory, California's carbon budget is presently dominated by fossil fuel emissions of CO2 (at >85% of total annual GHG emissions) to meet energy and transportation requirements. Other notable (non-ecosystem) sources of carbon GHG emissions in 2004 were from cement- and lime-making industries, livestock-based agriculture, and waste treatment activities. The NASA-CASA (Carnegie Ames Stanford Approach) simulation model based on satellite observations of monthly vegetation cover (including those from the Moderate Resolution Imaging Spectroradiometer - MODIS) has been used to estimate net ecosystem fluxes and vegetation biomass production over the period 1990-2004. California's annual NPP for all ecosystems in the early 2000s, estimated by CASA at 120 million metric tons of carbon equivalent (MMTCE) per year, was roughly equal to its annual fossil fuel emission rates for carbon. However, since natural ecosystems can accumulate only a small fraction of this annual NPP total in long-term storage pools, the net ecosystem sink flux for atmospheric carbon across the state was estimated at a maximum rate of between 15-24 MMTCE per year under favorable precipitation conditions. Under less favorable precipitation conditions, such as those experienced during the early 1990s, ecosystems statewide were estimated to have lost nearly 15 MMTCE per year to the atmosphere. Considering the large amounts of carbon stored in standing biomass of forests, shrublands, and rangelands across the state, the implications of changing climate and land use practices on ecosystems must be factored into the state’s planning to reduce overall GHG emissions.

  18. Neuroglobin over expressing mice

    DEFF Research Database (Denmark)

    Raida, Zindy; Hundahl, Christian Ansgar; Nyengaard, Jens R;

    2013-01-01

    thoroughly validated antibodies and oligos, we give a detailed brain anatomical characterization of transgenic mice over expressing Neuroglobin. Moreover, using permanent middle artery occlusion the effect of elevated levels of Neuroglobin on ischemic damage was studied. Lastly, the impact of mouse strain...... genetic background on ischemic damage was investigated. PRINCIPAL FINDINGS: A four to five fold increase in Neuroglobin mRNA and protein expression was seen in the brain of transgenic mice. A β-actin promoter was used to drive Neuroglobin over expression, but immunohistochemistry and in situ hybridization...... infarct volume 24 hours after ischemia. Immunohistochemistry showed no selective sparing of Neuroglobin expressing cells in the ischemic core or penumbra. A significant difference in infarct volume was found between mice of the same strain, but from different colonies. SIGNIFICANCE: In contrast to some...

  19. MICE Particle Identification Systems

    CERN Document Server

    Sanders, D A

    2009-01-01

    The international Muon Ionization Cooling Experiment (MICE) is being built, at the Rutherford Appleton Laboratory (RAL), to demonstrate the feasibility of ionization cooling of muon beams. This is one of the major technological steps needed in the development of a muon collider and a neutrino factory based on muon decays in a storage ring. MICE will use particle detectors to measure the cooling effect with high precision, achieving a precision on the measurement of emittance of 0.1% or better. The particle i.d. detectors and trackers must work in harsh environmental conditions due to high magnetic fringe fields and RF noise. We will briefly describe the MICE particle i.d. detector systems, and show some current performance measurements of these detectors.

  20. II Infused Mice

    Directory of Open Access Journals (Sweden)

    Justin L. Wilson

    2012-01-01

    Full Text Available The anti-inflammatory properties of PPAR-α plays an important role in attenuating hypertension. The current study determines the anti-hypertensive and anti-inflammatory role of PPAR-α agonist during a slow-pressor dose of Ang II (400 ng/kg/min. Ten to twelve week old male PPAR-α KO mice and their WT controls were implanted with telemetry devices and infused with Ang II for 12 days. On day 12 of Ang II infusion, MAP was elevated in PPAR-α KO mice compared to WT (161±4 mmHg versus 145±4 mmHg and fenofibrate (145 mg/kg/day reduced MAP in WT + Ang II mice (134±7 mmHg. Plasma IL-6 levels were higher in PPAR-α KO mice on day 12 of Ang II infusion (30±4 versus 8±2 pg/mL and fenofibrate reduced plasma IL-6 in Ang II-treated WT mice (10±3 pg/mL. Fenofibrate increased renal expression of CYP4A, restored renal CYP2J expression, reduced the elevation in renal ICAM-1, MCP-1 and COX-2 in WT + Ang II mice. Our results demonstrate that activation of PPAR-α attenuates Ang II-induced hypertension through up-regulation of CYP4A and CYP2J and an attenuation of inflammatory markers such as plasma IL-6, renal MCP-1, renal expression of ICAM-1 and COX-2.

  1. MICE Particle Identification System

    CERN Document Server

    Bogomilov, M

    2010-01-01

    The Muon Ionization Cooling Experiment, MICE, at the ISIS accelerator lo- cated at the Rutherford Appleton Laboratory, UK, will be the first experiment to study muon cooling at high precision. Demonstration of muon ionization cooling is an essential step towards the construction of a neutrino factory or a muon collider. Muons are produced by pion decay in a superconducting solenoid and reach MICE with a range of emittances and momenta. The purity of the muon beam is ensured by a system of particle detectors we will briefly describe here.

  2. 76 FR 55413 - Proposed Safe Harbor Agreement for California Red-legged Frog, California Tiger Salamander, Smith...

    Science.gov (United States)

    2011-09-07

    ... Register on June 17, 1999 (64 FR 32717), the Service would issue a permit to the Applicant authorizing take... Fish and Wildlife Service Proposed Safe Harbor Agreement for California Red-legged Frog, California... federally threatened California red-legged frog (Rana draytonii) and California tiger salamander...

  3. Contraceptive use and risk of unintended pregnancy in California

    OpenAIRE

    Foster, Diana; Bley, Julia; Mikanda, John; Induni, Marta; Arons, Abigail; Baumrind, Nikki; Darney, Philip D; Stewart, Felicia

    2004-01-01

    Abstract California is home to more than one out of eight American women of reproductive age. Because California has a large, diverse and growing population, national statistics do not necessarily describe the reproductive health of California women. This article presents risk for pregnancy and sexually transmitted infections among women in California based on the California Women’s Health Survey. Over 8900 women of reproductive age who participated in this survey between 1998 and 2001 pr...

  4. Bathymetry Hillshade--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore Pigeon Point, California. The raster data file is included in...

  5. Isopachs--Bolinas to Pescadero, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the sediment-thickness map of the Bolinas to Pescadero, California, region. The raster data file is included in...

  6. Transgressive Contours--Bolinas to Pescadero, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the transgressive contours for the Bolinas to Pescadero, California, region. The vector file is included in...

  7. Contours--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore Pigeon Point map area, California. The vector data file is...

  8. Bathymetry--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore Pigeon Point, California. The raster data file is included in...

  9. BackscatterA [8101]--Offshore Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Offshore of Pacifica map area, California. Backscatter data are provided as two separate grids...

  10. Backscatter B [8101]--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of the Offshore of Bolinas map area, California. Backscatter data are provided as separate grids...

  11. Backscatter D [Snippets]--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of the Offshore of Bolinas map area, California. Backscatter data are provided as separate grids...

  12. Faults--Offshore of Carpinteria, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3261 presents data for faults for the geologic and geomorphic map (see sheet 10, SIM 3261) of the Offshore of Carpinteria map area, California. The...

  13. Folds--Offshore of Ventura, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3254 presents data for folds for the geologic and geomorphic map (see sheet 10, SIM 3254) of the Offshore of Ventura map area, California. The...

  14. Faults--Offshore of Ventura, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3254 presents data for faults for the geologic and geomorphic map (see sheet 10, SIM 3254) of the Offshore of Ventura map area, California. The...

  15. Folds--Offshore of Santa Barbara, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3281 presents data for folds for the geologic and geomorphic map (see sheet 10, SIM 3281) of the Offshore of Santa Barbara map area, California....

  16. Folds--Offshore Refugio Beach, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3319 presents folds for the geologic and geomorphic map (see sheets 10, SIM 3319) of Offshore Refugio Beach, California. The vector data file is...

  17. Faults--Offshore Refugio Beach, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3319 presents folds for the geologic and geomorphic map (see sheets 10, SIM 3319) of Offshore Refugio Beach, California. The vector data file is...

  18. Folds--Offshore of Carpinteria, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3261 presents data for folds for the geologic and geomorphic map (see sheet 10, SIM 3261) of the Offshore of Carpinteria map area, California. The...

  19. Earthquakes in Central California, 1980-1984

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — There have been many earthquake occurrences in central California. This set of slides shows earthquake damage from the following events: Livermore, 1980, Coalinga,...

  20. Bathymetry--Offshore of Carpinteria, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3261 presents data for the bathymetry and shaded-relief maps (see sheets 1, 2, SIM 3261) of the Offshore of Carpinteria map area, California. The...

  1. Bathymetry--Offshore Half Moon Bay, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of the Offshore Half Moon Bay, California (raster data file is included in...

  2. California Ocean Uses Atlas: Fishing sector

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset is a result of the California Ocean Uses Atlas Project: a collaboration between NOAA's National Marine Protected Areas Center and Marine Conservation...

  3. Newborn Screening Disorders, California, 2009-2014

    Data.gov (United States)

    U.S. Department of Health & Human Services — This table presents counts of disorders that have been diagnosed by the California Newborn Screening program during the five-year period from 2009 through 2014....

  4. Habitat--Offshore Scott Creek, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Scott Creek map area, California. The vector data file is included in...

  5. Faults--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the faults for the geologic and geomorphic map of the Offshore Santa Cruz map area, California. The vector data file is...

  6. Folds--Offshore Scott Creek, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the folds for the geologic and geomorphic map of the Offshore of Scott Creek map area, California. The vector data file is...

  7. Folds--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the folds for the geologic and geomorphic map of the Offshore Pigeon Point map area, California. The vector data file is...

  8. Contours Offshore of Tomales Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Tomales Point map area, California. The vector data file...

  9. Folds--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the folds for the geologic and geomorphic map of the Offshore Santa Cruz map area, California. The vector data file is...

  10. Habitat--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Pigeon Point map area, California. The vector data file is included in...

  11. Habitat--Offshore of Aptos, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Aptos map area, California. The vector data file is included in...

  12. Habitat--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Santa Cruz map area, California. The vector data file is included in...

  13. Faults--Offshore Pigeon Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the faults for the geologic and geomorphic map of the Offshore Pigeon Point map area, California. The vector data file is...

  14. Habitat--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Monterey Canyon and Vicinity map area, California. The vector data file is included in...

  15. Status of six endangered California Butterflies 1977

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A survey was conducted from March-September 1977 to determine the current status of six federally endangered butterflies which reside in California. The butterflies...

  16. Alluvial Boundary of California's Central Valley

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the extent of the alluvial deposits in the Central Valley of California and encompasses the contiguous Sacramento, San Joaquin, and...

  17. Contours--Offshore Coal Oil Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3302 presents bathymetric contours for several seafloor maps of Offshore Coal Oil Point, California (vector data file is included in...

  18. Bathymetry--Offshore of San Francisco, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore of San Francisco, California (raster data file is included in...

  19. Gravity Data for California and Southern Nevada

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The gravity data (88,514 records) were compiled largely from a state-wide regional gravity study program organized by the California Division of Mines and Geology...

  20. Contours--Offshore of Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Pacifica map area, California. The vector data file is...

  1. Coccidioidomycosis among Prison Inmates, California, USA, 2011

    Centers for Disease Control (CDC) Podcasts

    2015-02-26

    Dr. Charlotte Wheeler discusses Coccidioidomycosis among Prison Inmates in California.  Created: 2/26/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/26/2015.

  2. California Least Tern Breeding Survey 1995 Season

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Sterna antillarum browni) nested at 37 sites along the coast of California. This 7% decrease in breeding population size from 1994 brings to an end the trend since...

  3. X-Ray Technologist Listing In California

    Data.gov (United States)

    U.S. Department of Health & Human Services — This table represents a current listing of X-Ray Technologists who are licensed by Radiologic Health Branch (RHB) of the California Department of Public Health. RHB...

  4. Habitat--Offshore of Salt Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Salt Point map area, California. The vector data file is included in...

  5. Contours-Offshore of Bodega Head, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Bodega Head map area, California. The vector data file...

  6. Bathymetry Hillshade--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore Santa Cruz, California. The raster data file is included in...

  7. Contours--Offshore of Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Bolinas map area, California. The vector data file is...

  8. Contours--Offshore of San Francisco, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of San Francisco map area, California. The vector data file...

  9. Bathymetry--Offshore of Bodega Head, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of the Offshore of Bodega Head map area, California. Raster data file is included in...

  10. Bathymetry--Offshore of Tomales Point, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of the Offshore of Tomales Point map area, California. Raster data file is included in...

  11. BackscatterB [7125]--Offshore Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Offshore of Pacifica map area, California. Backscatter data are provided as two separate grids...

  12. Bathymetry Hillshade--Offshore of Ventura, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3254 presents data for the bathymetry and shaded-relief maps (see sheets 1, 2, SIM 3254) of the Offshore of Ventura map area, California. The...

  13. Backscatter A [8101]--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of the Offshore of Bolinas map area, California. Backscatter data are provided as separate grids...

  14. Backscatter A [8101]--Offshore San Gregorio, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3306 presents data for the acoustic-backscatter map (see sheet 3, SIM 3306) of the Offshore of San Gregorio map area, California. Backscatter data...

  15. Backscatter E [Swath]--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of the Offshore of Bolinas map area, California. Backscatter data are provided as separate grids...

  16. Backscatter [SWATH]--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Offshore of Santa Cruz map area, California. Backscatter data are provided as three separate...

  17. Northern California 36 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 36-second Northern California Elevation Grid provides bathymetric data in ASCII raster format of 36-second resolution in geographic coordinates. This grid is...

  18. Central California 3 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 3-second Central California Elevation Grid provides bathymetric data in ASCII raster format of 3-second resolution in geographic coordinates. This grid is...

  19. Northern California 6 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 6-second Northern California Elevation Grid provides bathymetric data in ASCII raster format of 6-second resolution in geographic coordinates. This grid is...

  20. Marine Invertebrate assemblages in southern California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This is a point file of invertebrate site clusters calculated from benthic trawls completed by the Southern California Coastal Water Research Project (SCCWRP). Data...

  1. Nearshore marine fish assemblages in southern California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fish benthic trawls were completed by the Southern California Coastal Water Research Project (SCCWRP). Data from 425 fisheries independent trawls ranging from 2-215...

  2. Fish assemblages in southern California kelp forests.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This is a point file of fish assemblages calculated from diver surveys in kelp forests in Southern California. Visual census data was combined for two separate...

  3. Violent Crime Rate California 2006-2010

    Data.gov (United States)

    U.S. Department of Health & Human Services — This table contains data on the rate of violent crime (crimes per 1,000 population) for California, its regions, counties, cities and towns. Crime and population...

  4. Backscatter B [7125]--Offshore San Gregorio, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3306 presents data for the acoustic-backscatter map (see sheet 3, SIM 3306) of the Offshore of San Gregorio map area, California. Backscatter data...

  5. Botaanikud Chamisso ja Eschscholtz Californias / Tiiu Speek

    Index Scriptorium Estoniae

    Speek, Tiiu, 1958-

    2012-01-01

    Loodusteadlaste A. von Chamisso ja J. Fr. Eschscholtzi osalemisest O. von Kotzebue ekspeditsioonidel (1815-1818 ning 1823-1826); reisidel kogutud ja kirjeldatud USA lääneosa ja California taimeliikidest ning neist koostatud herbaariumite saatusest

  6. Backscatter C [7125]--Offshore Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of the Offshore of Bolinas map area, California. Backscatter data are provided as separate grids...

  7. Seafloor character--Offshore of Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents the seafloor-character map Offshore of Pacifica, California. The raster data file is included in "SFC_OffshorePacifica.zip," which is...

  8. Seafloor character--Offshore of Bolinas, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents the seafloor-character map Offshore of Bolinas, California (raster data file is included in "SeafloorCharacter_OffshoreBolinas.zip,"...

  9. Humboldt, California 1 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 1-second Humboldt, California Elevation Grid provides bathymetric data in ASCII raster format of 1-second resolution in geographic coordinates. This grid is...

  10. California Ocean Uses Atlas: Industrial sector

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset is a result of the California Ocean Uses Atlas Project: a collaboration between NOAA's National Marine Protected Areas Center and Marine Conservation...

  11. Contours--Offshore of Fort Ross, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore of Fort Ross map area, California. The vector data file is...

  12. Humboldt Bay, California Benthic Habitats 2009 Geodatabase

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Humboldt Bay is the largest estuary in California north of San Francisco Bay and represents a significant resource for the north coast region. Beginning in 2007 the...

  13. Historical Fire Perimeters - Southern California [ds384

    Data.gov (United States)

    California Department of Resources — CDF, USDA Forest Service Region 5, BLM, NPS, Contract Counties and other agencies jointly maintain a comprehensive fire perimeter GIS layer for public and private...

  14. Faults--Offshore Scott Creek, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the faults for the geologic and geomorphic map of the Offshore of Scott Creek map area, California. The vector data file is...

  15. Seafloor character--Offshore of Carpinteria, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3261 presents data for the seafloor-character map (see sheet 5, SIM 3261) of the Offshore of Carpinteria map area, California. The raster data file...

  16. Faults--Offshore of Santa Barbara, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3281 presents data for folds for the geologic and geomorphic map (see sheet 10, SIM 3281) of the Offshore of Santa Barbara map area, California....

  17. Habitat--Offshore of Pacifica, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Offshore of Pacifica map area, California. The vector data file is included in...

  18. Habitat--Drakes Bay and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Drakes Bay and Vicinity map area, California. The vector data file is included in...

  19. Contours--Offshore Refugio Beach, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3319 presents bathymetric contours for several seafloor maps of Offshore Refugio Beach, California (vector data file is included in...

  20. Bathymetry Hillshade--Offshore of Carpinteria, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3261 presents data for the bathymetry and shaded-relief maps (see sheets 1, 2, SIM 3261) of the Offshore of Carpinteria map area, California. The...

  1. Contours--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetric contours for several seafloor maps of the Offshore Santa Cruz map area, California. The vector data file is...

  2. Bathymetry--Offshore Santa Cruz, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the bathymetry and shaded-relief maps of Offshore Santa Cruz, California. The raster data file is included in...

  3. Contours--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents bathymetric contours for several seafloor maps of the Monterey Canyon and Vicinity map area, California. The raster data file is...

  4. Housing... the Hillside Los Angeles, California

    OpenAIRE

    Vallen, Michael Earl

    1993-01-01

    Housing... the Hillside Los Angeles, California by Michael Vallen Gregory Hunt, Chairman College of Architecture and Urban Planning (ABSTRACT) This Thesis is a proposal for a prototypical hillside housing community in Los Angeles, California. As a prototype it is responsible for setting an architectural precedent. In this effort, the Thesis continues with focus on issues of construction methodology, urban planning, and land use relationships concerning t...

  5. Climate change and California surface hydrology

    OpenAIRE

    Schwartz, Marla Ann

    2016-01-01

    Understanding 21st century changes in California surface hydrology is critical to ensuring enough freshwater resources for the state’s municipal, ecological and agricultural purposes and assessing future ecosystem health and wildfire risk. To project 21st century surface hydrology over California – a region with highly complex topography that is not well captured by global climate models (GCMs) – downscaling is necessary. This work projects future changes in surface hydrology over the Los Ang...

  6. California Methanol Assessment; Volume II, Technical Report

    OpenAIRE

    O'Toole, R.; Dutzi, E.; Gershman, R.; Heft, R.; Kalema, W.; Maynard, D.

    1983-01-01

    A joint effort by the Jet Propulsion Laboratory and the California Institute of Technology Division of Chemistry and Chemical Engineering has brought together sponsors from both the public and private sectors for an analysis of the prospects for methanol use as a fuel in California, primarily for the transportation and stationary application sectors. Increasing optimism in 1982 for a slower rise in oil prices and a more realistic understanding of the costs of methanol production have had a ne...

  7. Cancer mortality in cerebral palsy in California

    OpenAIRE

    Day, Steven,; Brooks, Jordan; Strauss, David; Shumway, Sharon; Shavelle, Robert; Kush, Scott; Sasco, Annie

    2008-01-01

    Exposure to lifestyle, occupational, and environmental risk factors for cancer are undoubtedly different in cerebral palsy (CP) than in the general population, and these differences and others may result in a specific pattern of cancer mortality in CP. Objective: To study the cancer mortality of CP in California. Study group: 40,482 CP cases (contributing 357,928 person-years) among 210,155 persons having received annual evaluations from the California Department of Developmental Services ove...

  8. What Is the Southern California Earthquake Center?

    OpenAIRE

    Aki, Keiiti; Henyey, Thomas; Heaton, Thomas

    1991-01-01

    On February 11, Congressman George E. Brown, Jr., Chairman of the House Committee on Science, Space and Technology, together with the National Science Foundation, the U.S. Geological Survey, and state and local officials, helped inaugurate the Southern California Earthquake Center (SCEC) on the campus of the University of Southern California. SCEC is one of 14 new NSF Science and Technology Centers and includes a substantial commitment from the USGS for FY91. The center is a consortium of sev...

  9. California's county hospitals and the University of California graduate medical education system. Current issues and future directions.

    OpenAIRE

    Jameson, W J; Pierce, K; Martin, D K

    1998-01-01

    California's county hospitals train 45% of the state's graduate medical residents, including 33% of residents in the University of California system. This paper describes the interrelationships of California's county hospitals and the University of California (UC) graduate medical education (GME) programs, highlighting key challenges facing both systems. The mission of California's county health care systems is to serve all who need health care services regardless of ability to pay. Locating ...

  10. Energy subsidies in California's electricity market deregulation

    International Nuclear Information System (INIS)

    Deregulation and re-regulation of California's electricity market not only failed in terms of anticipated cost reductions, improved customer service and higher competition, it also led to the introduction of various additional energy subsidies. This paper analyzes California's electricity market deregulation process from a subsidy viewpoint. Under deregulation in California, investor-owned utilities were not allowed to pass their energy procurement costs fully on to their customers, and therefore subsequently, and inevitably, ran into severe financial problems. Such retail price regulation is an energy subsidy that is both economically and environmentally unfavorable, because it veils true price signals to electricity consumers and, in this way, discourages energy conservation. Other policies implemented in California that represent perverse energy subsidies are the purchase of power by the state of California, the suspension of retail competition, and the potential misuse of money from the recovery of stranded costs. Many interventions implemented by the state to smooth out the impacts of the energy crisis insulated electricity consumers from market realities, supported the existing structure of California's electricity market, which is predominantly based on fossil fuels, and suppressed market incentives to improve energy conservation

  11. 3-D Perspective Pasadena, California

    Science.gov (United States)

    2000-01-01

    This perspective view shows the western part of the city of Pasadena, California, looking north towards the San Gabriel Mountains. Portions of the cities of Altadena and La Canada, Flintridge are also shown. The image was created from three datasets: the Shuttle Radar Topography Mission (SRTM) supplied the elevation data; Landsat data from November 11, 1986 provided the land surface color (not the sky) and U.S. Geological Survey digital aerial photography provides the image detail. The Rose Bowl, surrounded by a golf course, is the circular feature at the bottom center of the image. The Jet Propulsion Laboratory is the cluster of large buildings north of the Rose Bowl at the base of the mountains. A large landfill, Scholl Canyon, is the smooth area in the lower left corner of the scene. This image shows the power of combining data from different sources to create planning tools to study problems that affect large urban areas. In addition to the well-known earthquake hazards, Southern California is affected by a natural cycle of fire and mudflows. Wildfires strip the mountains of vegetation, increasing the hazards from flooding and mudflows for several years afterwards. Data such as shown on this image can be used to predict both how wildfires will spread over the terrain and also how mudflows will be channeled down the canyons. The Shuttle Radar Topography Mission (SRTM), launched on February 11, 2000, uses the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. The mission was designed to collect three dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, an additional C-band imaging antenna and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency

  12. The Story of California. Teacher's Guide = Guia del Maestro de La Historia de California.

    Science.gov (United States)

    Gray (Naomi) Associates, Inc., San Francisco, CA.

    The teacher's guide is designed to accompany "The Story of California," a Spanish-English bilingual history and geography of the state intended for classroom use by limited-English-proficient, native Spanish-speaking students in California's urban middle schools. The guide describes classroom activities coordinated with the student's workbook and…

  13. Mice Drawer System

    Science.gov (United States)

    Cancedda, Ranieri

    2008-01-01

    The Mice Drawer System (MDS) is an Italian Space Agency (ASI) facility which is able to support mice onboard the International Space Station during long-duration exploration missions (from 100 to 150-days) by living space, food, water, ventilation and lighting. Mice can be accommodated either individually (maximum 6) or in groups (4 pairs). MDS is integrated in the Space Shuttle middeck during transportation (uploading and downloading) to the ISS and in an EXPRESS Rack in Destiny, the US Laboratory during experiment execution. Osteoporosis is a debilitating disease that afflicts millions of people worldwide. One of the physiological changes experienced by astronauts during space flight is the accelerated loss of bone mass due to the lack of gravitational loading on the skeleton. This bone loss experienced by astronauts is similar to osteoporosis in the elderly population. MDS will help investigate the effects of unloading on transgenic (foreign gene that has been inserted into its genome to exhibit a particular trait) mice with the Osteoblast Stimulating Factor-1, OSF-1, a growth and differentiation factor, and to study the genetic mechanisms underlying the bone mass pathophysiology. MDS will test the hypothesis that mice with an increased bone density are likely to be more protected from osteoporosis, when the increased bone mass is a direct effect of a gene involved in skeletogenesis (skeleton formation). Osteoporosis is a debilitating disease that afflicts millions worldwide. One of the physiological changes experienced by astronauts during space flight is the accelerated loss of bone mass due to the lack of gravitational loading on the skeleton, a loss that is similar to osteoporosis in the elderly population on Earth. Osteoblast Stimulating Factor-1 (OSF-1), also known as pleiotrophin (PTN) or Heparin-Binding Growth- Associated Molecule (HB-GAM) belongs to a family of secreted heparin binding proteins..OSF-1 is an extracellular matrix-associated growth and

  14. The MICE PID Instrumentation

    CERN Document Server

    Bonesini, M

    2008-01-01

    The international Muon Ionization Cooling Experiment (MICE) will carry out a systematic investigation of ionization cooling of a muon beam. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation is needed to measure particle coordinates and timing vs RF. A PID system based on three time-of-flight stations, two Aerogel Cerenkov detectors and a KLOE-like calorimeter has been constructed in order to keep beam contamination ($e, \\pi$) well below 1%. The MICE time-of-flight system will measure timing with a resolution better than 70 ps per plane, in a harsh environment due to high particle rates, fringe magnetic fields and electron backgrounds from RF dark current.

  15. Status of MICE

    OpenAIRE

    Bross, Alan D.; Kaplan, Daniel M.

    2008-01-01

    Muon ionization cooling is the only practical method for preparing high-brilliance beams needed for a neutrino factory or muon collider. The muon ionization cooling experiment (MICE) under development at the Rutherford Appleton Laboratory comprises a dedicated beamline to generate a range of input emittance and momentum, with time-of-flight and Cherenkov detectors to ensure a pure muon beam. A first measurement of emittance is performed in the upstream magnetic spectrometer with a scintillati...

  16. The MICE PID Instrumentation

    OpenAIRE

    M. Bonesini(Sezione INFN Milano Bicocca, Dipartimento di Fisica G. Occhialini, Milano, Italy)

    2008-01-01

    The international Muon Ionization Cooling Experiment (MICE) will carry out a systematic investigation of ionization cooling of a muon beam. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation is needed to measure particle coordinates and timing vs RF. A PID system based on three time-of-flight stations, two Aerogel Cerenkov detectors and a KLOE-like calorimeter has been constructed in order to keep beam contamination ($e, \\pi$) well be...

  17. Retinoblastoma in transgenic mice

    OpenAIRE

    Windle, J J; Albert, D. M.; O'Brien, J. M.; Marcus, D. M.; Disteche, Ch.M.; Bernards, R.A.; Mellon, P L

    1990-01-01

    Retinoblastoma, a malignancy of the eye occurring in young children, has been widely studied as a model for genetic predisposition to cancer. This disease is caused by mutations in both alleles of an anti-oncogene (the retinoblastoma gene, Rb) that inactivate or eliminate the Rb encoded protein, pl05rb. Here we report that expression of a viral oncogene, the simian virus 40 T antigen, in the retina of transgenic mice produces heritable ocular tumours with histological, ultrastructural and imm...

  18. Transthoracic Echocardiography in Mice

    OpenAIRE

    Respress, Jonathan L.; Wehrens, Xander H. T.

    2010-01-01

    In recent years, murine models have become the primary avenue for studying the molecular mechanisms of cardiac dysfunction resulting from changes in gene expression. Transgenic and gene targeting methods can be used to generate mice with altered cardiac size and function,1-3 and as a result, in vivo techniques are needed to evaluate their cardiac phenotype. Transthoracic echocardiography, pulse wave Doppler (PWD), and tissue Doppler imaging (TDI) can be used to provide dimensional measurement...

  19. Organochloride pesticides in California sea lions revisited

    Directory of Open Access Journals (Sweden)

    Tanabe Shinsuke

    2002-12-01

    Full Text Available Abstract Background Dichlorodiphenyltrichloroethane (DDT and polychlorinated biphenyls (PCBs are ubiquitous environmental contaminants that have been banned in most countries, but considerable amounts continue to cycle the ecosphere. Top trophic level predators, like sea birds and marine mammals, bioaccumulate these lipophilic compounds, reflecting their presence in the environment. Results We measured concentrations of tDDT (p,p' - DDT + p,p' - DDD + p,p' - DDE and PCBs in the blubber of dead California sea lions stranded along the California coast. tDDT and PCB concentrations were 150 ± 257 ug/g lipid weight (mean ± SD and 44 ± 78 ug/g lipid weight, respectively. There were no differences in tDDT or PCB concentrations between animal categories varying in sex or age. There was a trend towards a decrease in tDDT and PCB concentrations from northern to southern California. The lipid content of the blubber was negatively correlated with levels of tDDT and PCBs. tDDT concentrations were approximately 3 times higher than PCB concentrations. Conclusions tDDT levels in the blubber of California sea lions decreased by over one order of magnitude from 1970 to 2000. PCB level changes over time were unclear owing to a paucity of data and analytical differences over the years. Current levels of these pollutants in California sea lions are among the highest among marine mammals and exceed those reported to cause immunotoxicity or endocrine disruption.

  20. Industrial Physics---Southern California Style

    Science.gov (United States)

    Leslie, Stuart

    2013-03-01

    Only in Southern California did space-age style really come into its own as a unique expression of Cold War scientific culture. The corporate campuses of General Atomic in San Diego and North American Aviation in Los Angeles perfectly expressed the exhilarating spirit of Southern California's aerospace era, scaling up the residential version of California modernism to industrial proportion. Architects William Pereira and A.C. Martin Jr., in collaboration with their scientific counterparts, fashioned military-industrial `dream factories' for industrial physics that embodied the secret side of the space-age zeitgeist, one the public could only glimpse of in photographs, advertisements, and carefully staged open houses. These laboratories served up archetypes of the California dream for a select audience of scientists, engineers, and military officers, live-action commercials for a lifestyle intended to lure the best and brightest to Southern California. Paradoxically, they hid in plain sight, in the midst of aerospace suburbs, an open secret, at once visible and opaque, the public face of an otherwise invisible empire. Now, at the end of the aerospace era, these places have become an endangered species, difficult to repurpose, on valuable if sometimes highly polluted land. Yet they offer an important reminder of a more confident time when many physicists set their sights on the stars.

  1. Summary of California DSM impact evaluation studies

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A. [Oak Ridge National Lab., TN (United States); Mihlmester, P.E. [Aspen Systems Corp., Oak Ridge, TN (United States)

    1994-10-01

    Over the past several years, four of the largest investor-owned California utilities have completed more than 50 evaluation studies designed to measure the energy and demand impacts of their demand-side management (DSM) programs. These four are: Pacific Gas and Electric (PG and E), Southern California Edison (SCE), Southern California Gas (SoCalGas), and San diego Gas and Electric (SDG and E). These studies covered residential, commercial, industrial, and agricultural DSM programs and provided a wealth of information on program impacts. The objective of this report is to summarize the results of these DSM evaluation studies in order to describe what DSM has achieved in California, to assess how well these achievements were forecast, and to compare the effectiveness of different types of DSM programs. This report documents the sizable investment made by the California utilities in their 1990--92 DSM programs. Between 1990 and 1992, the four utilities spent $772 million on energy-efficiency/conservation programs. This report also summarizes the realization rates estimated by the 50+ evaluation studies. Realization rates are defined as ex-post net savings estimates divided by ex-ante net savings estimates. Realization rates are summarized for 158 programs and program segments.

  2. What went wrong in California's electricity market?

    International Nuclear Information System (INIS)

    The California electricity market reform promised to deliver reliable service at low and stable prices. Frequent capacity shortages and the ensuing rolling black-outs, price spikes, and large price volatility since Summer 2000 raise a simple but substantive question: what went wrong? The answer to this question will help countries contemplating electricity market reform not to commit similar mistakes. We find the answer by identifying the major factors that have turned the California dream into a nightmare. Such factors include poor market design, market power, sustained demand growth not matched by new capacity, rising marginal cost, and financial insolvency. Proposed remedies include an alternative market settlement process, long-term contract, fast licensing and siting process for new generation and transmission, conservation and energy-efficiency, distributed resources, rate options, and debt restructuring. The California experience suggests that a reversible regulatory reform is a safe alternative to an irreversible market reform. (Author)

  3. Adjoint tomography of the southern California crust.

    Science.gov (United States)

    Tape, Carl; Liu, Qinya; Maggi, Alessia; Tromp, Jeroen

    2009-08-21

    Using an inversion strategy based on adjoint methods, we developed a three-dimensional seismological model of the southern California crust. The resulting model involved 16 tomographic iterations, which required 6800 wavefield simulations and a total of 0.8 million central processing unit hours. The new crustal model reveals strong heterogeneity, including local changes of +/-30% with respect to the initial three-dimensional model provided by the Southern California Earthquake Center. The model illuminates shallow features such as sedimentary basins and compositional contrasts across faults. It also reveals crustal features at depth that aid in the tectonic reconstruction of southern California, such as subduction-captured oceanic crustal fragments. The new model enables more realistic and accurate assessments of seismic hazard. PMID:19696349

  4. Health Effects of the 2003 Southern California Wildfires on Children

    OpenAIRE

    Künzli, Nino; Avol, Ed; Wu, Jun; Gauderman, W. James; Rappaport, Ed; Millstein, Joshua; Bennion, Jonathan; McConnell, Rob; Gilliland, Frank D.; Berhane, Kiros; Lurmann, Fred; Winer, Arthur; Peters, John M.

    2006-01-01

    Rationale: In late October 2003, Southern California wildfires burned more than 3,000 km2. The wildfires produced heavy smoke that affected several communities participating in the University of Southern California Children's Health Study (CHS).

  5. Elsasser and Rhode: Further Notes on California Charmstones

    OpenAIRE

    Parkman, E. Breck

    2001-01-01

    Further Notes on California Charmstones . Albert B. Elsasser and Peter T. Rhode. Coyote Press Archives of California Prehistory, Number 38. Salinas: Coyote Press, 1996. 144 pp., 15 figs., 3 charts, 1 sketch, 3 appendices, 1112.00 (paper).

  6. Breschini and Haversat, eds.: Papers on Central California Prehistory

    OpenAIRE

    Elsasser, A B

    1985-01-01

    Papers on Central California Prehistory: 1. Gary S. Breschini and Trudy Haversat, series editors. Salinas, CA. Coyote Press Archives of California Prehistory, No. 3, 1984. 87 pp., figures, tables, photos, $4.95, (paper).

  7. California State Waters Map Series--Drakes Bay Web Services

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — In 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of...

  8. Teale California Ambient Air Quality Standards for carbon monoxide

    Data.gov (United States)

    California Department of Resources — California Spatial Information System (CaSIL) is a project designed to improve access to geo-spatial and geo-spatial related data information throughout the state...

  9. Fruit and Vegetable Consumption in California Residents, 2012/2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — Percentage of California residents who consumed five or more servings of fruits and vegetables a day. These data are from the 2013 California Dietary Practices...

  10. Fire Perimeters - Southern California, Fall 2007 [ds385

    Data.gov (United States)

    California Department of Resources — Southern Callifornia fire perimeters for the Fall 2007 wildfires. The perimeters were assembled from various sources by California Department of Fish and Game (DFG)...

  11. Williamson Act - The California Land Conservation Act of 1965

    Data.gov (United States)

    California Department of Resources — The California Land Conservation Act of 1965 - commonly referred to as the Williamson Act - is the State's primary program for the conservation of private land in...

  12. California State Waters Map Series--Hueneme Canyon Web Services

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — In 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of...

  13. The Case of Segraves v. State of California.

    Science.gov (United States)

    Flygare, Thomas J.

    1981-01-01

    Discusses the complaint that led to the case of Seagraves et al. versus State of California et al., the "anti-dogmatism" policy adopted by the California state board of education in 1972, and the outcome of the trial. (WD)

  14. Teale California Ambient Air Quality Standards for Ozone

    Data.gov (United States)

    California Department of Resources — California Spatial Information System (CaSIL) is a project designed to improve access to geo-spatial and geo-spatial related data information throughout the state...

  15. California community water systems annual indicators dataset, 1999-2008

    Data.gov (United States)

    California Environmental Health Tracking Program — This data set contains annual measures of arsenic and nitrates in public drinking water supplies. Data are derived from California Office of Drinking Water (ODW)...

  16. California community water systems quarterly indicators dataset, 1999-2008

    Data.gov (United States)

    California Environmental Health Tracking Program — This data set contains quarterly measures of arsenic and nitrates in public drinking water supplies. Data are derived from California Office of Drinking Water (ODW)...

  17. Integrated Climate Change Impacts Assessment in California

    Science.gov (United States)

    Cayan, D. R.; Franco, G.; Meyer, R.; Anderson, M.; Bromirski, P. D.

    2014-12-01

    This paper summarizes lessons learned from an ongoing series of climate change assessments for California, conducted by the scientific community and State and local agencies. A series of three Assessments have considered vulnerability and adaptation issues for both managed and natural systems. California's vulnerability is many faceted, arising because of an exceptionally drought prone climate, open coast and large estuary exposure to sea level rise, sensitive ecosystems and complex human footprint and economy. Key elements of the assessments have been a common set of climate and sea-level rise scenarios, based upon IPCC GCM simulations. Regionalized and localized output from GCM projections was provided to research teams investigating water supply, agriculture, coastal resources, ecosystem services, forestry, public health, and energy demand and hydropower generation. The assessment results are helping to investigate the broad range of uncertainty that is inherent in climate projections, and users are becoming better equipped to process an envelope of potential climate and impacts. Some projections suggest that without changes in California's present fresh-water delivery system, serious water shortages would take place, but that technical solutions are possible. Under a warmer climate, wildfire vulnerability is heightened markedly in some areas--estimated increases in burned area by the end of the 21st Century exceed 100% of the historical area burned in much of the forested areas of Northern California Along California coast and estuaries, projected rise in mean sea level will accelerate flooding occurrences, prompting the need for better education and preparedness. Many policymakers and agency personnel in California are factoring in results from the assessments and recognize the need for a sustained assessment process. An ongoing challenge, of course, is to achieve more engagement with a broader community of decision makers, and notably with the private sector.

  18. Electric industry restructuring in California: For better or worse

    International Nuclear Information System (INIS)

    Due to the sheer size of its economy, California economic policy often influences and shapes not only California's economy, but markets and public economic policy throughout the Western states and the nation as well. For better or worse, undoubtedly this effect is being seen in the current debate about restructuring electricity markets. This article examines what is happening in California, and what impact the evolving changes in California's electric system may have in neighboring states and elsewhere

  19. Tobacco Control in California 2003-2007: Missed Opportunities

    OpenAIRE

    Hong, MPH, Mi-Kyung; Barnes; Glantz,, Stanton PhD

    2007-01-01

    While smoking prevalence in California continued its decline (reaching an historic low of 13.3% in 2006), this rate was slower than in earlier years, reflecting the fact that tobacco control efforts in California in the period 2003-2007 continued to drift, with no clear indications that California would regain its international leadership in tobacco control. Neither the Schwarzenegger Administration nor the California Legislature sought to divert the Proposition 99 funding allocation...

  20. California wine industry evolving to compete in 21st century

    OpenAIRE

    Goodhue, Rachael; Green, Richard; Heien, Dale; Martin, Philip

    2008-01-01

    The California wine industry is growing and changing amidst a global revolution in grape growing, wine production, wine marketing and consumer tastes. California accounted for roughly 90% of the value of U.S. wine production in 2006. U.S. per capita wine consumption and the quality of wine consumed continue to rise. The largest California wineries have long accounted for most California wine shipments and continue to expand with respect to volume and number of labels. While small wineries sel...

  1. Carotid chemoreceptor development in mice

    OpenAIRE

    Shirahata, Machiko; Kostuk, Eric W.; Pichard, Luis E

    2012-01-01

    Mice are the most suitable species for understanding genetic aspects of postnatal developments of the carotid body due to the availability of many inbred strains and knockout mice. Our study has shown that the carotid body grows differentially in different mouse strains, indicating the involvement of genes. However, the small size hampers investigating functional development of the carotid body. Hypoxic and/or hyperoxic ventilatory responses have been investigated in newborn mice, but these r...

  2. Case Study of the California Cement Industry

    OpenAIRE

    Coito, Fred; Powell, Frank; Worrell, Ernst; Price, Lynn; Friedmann, Rafael

    2005-01-01

    California is the largest cement producing state in the U.S., accounting for between 10 percent and 15 percent of U.S. cement production and cement industry employment. The cement industry in California consists of 31 sites that consume large amounts of energy, annually: 1,600 GWh of electricity, 22 million therms of natural gas, 2.3 million tons of coal, 0.25 tons of coke, and smaller amounts of waste materials, including tires. The case study summarized in this paper focused on providi...

  3. Competitive ancillary service procurement in California

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; Siddiqui, Afzal S.; Khavkin, Mark

    2000-01-01

    California has undertaken a major restructuring of its electricity utility sector. Most electricity is now sold in open markets operated by the PX and other entities. Bilateral contracting among some market participants is also permitted. A group of independent generating companies bids into these markets together with out of state resources. In addition to these markets, CAISO operates markets for both imbalance energy and AS, a quite unusual feature of the California system. These markets were initially quite chaotic and were rife with market power problems. However, various reforms have now created a system that functions well. During the restructuring process, special provisions were made to protect public purpose programs, including renewable generation.

  4. BSE Prevention Update: Comparing France and California

    OpenAIRE

    Maas, John

    2004-01-01

    Over the past four months we have read and heard more about BSE (Bovine Spongiform Encephalopathy; Mad Cow Disease) than we may have ever wanted to know. The California Cattlemen’s Association and other allied groups, particularly the NCBA have done a wonderful job in terms of getting out the facts about BSE and the message that beef is safe for consumers. The BSE issue is extremely complicated and I will compare some of what has been done in France with our situation in California. ...

  5. USA: California rejects mandatory GMO labelling

    OpenAIRE

    Paull, John

    2012-01-01

    Buying organic remains the best strategy for US consumers to avoid eating GM food. The voters of California have rejected the proposal to label GMO food. The proposition was narrowly lost, 47% to 53% (4,326,770 ‘Yes’ votes vs. 4,884,961 ‘No’ votes). Proposition 47 was supported by the organic sector but opposed by a coalition of GMO companies and US multinational food companies. Californians were invited to vote into law ‘The California Right to Know Genetically Engineered Food Act’. Section ...

  6. CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice.

    Science.gov (United States)

    Ramirez, Alejandro; Co, Mary; Mathew, Anuja

    2016-01-01

    Several studies have shown a reduced efficacy of influenza vaccines in the elderly compared to young adults. In this study, we evaluated the immunogenicity and protective efficacy of a commercially available inactivated influenza vaccine (Fluzone®) in young adult and aged mice. C57/BL6 mice were administered a single or double immunization of Fluzone® with or without CpG and challenged intranasally with H1N1 A/California/09 virus. A double immunization of Fluzone® adjuvanted with CpG elicited the highest level of protection in young adult mice which was associated with increases in influenza specific IgG, elevated HAI titres, reduced viral titres and lung inflammation. In contrast, the vaccine schedule which provided fully protective immunity in young adult mice conferred limited protection in aged mice. Antigen presenting cells from aged mice were found to be less responsive to in vitro stimulation by Fluzone and CpG which may partially explain this result. Our data are supportive of studies that have shown limited effectiveness of influenza vaccines in the elderly and provide important information relevant to the design of more immunogenic vaccines in this age group. PMID:26934728

  7. Of mice and men

    DEFF Research Database (Denmark)

    Andersen, Troels Askhøj; Troelsen, Karin de Linde Lind; Larsen, Lars Allan

    2014-01-01

    Congenital heart disease (CHD) affects nearly 1 % of the population. It is a complex disease, which may be caused by multiple genetic and environmental factors. Studies in human genetics have led to the identification of more than 50 human genes, involved in isolated CHD or genetic syndromes, where...... CHD is part of the phenotype. Furthermore, mapping of genomic copy number variants and exome sequencing of CHD patients have led to the identification of a large number of candidate disease genes. Experiments in animal models, particularly in mice, have been used to verify human disease genes and to...

  8. Emittance Measurement in MICE

    OpenAIRE

    Hart, Terrence L.; Kaplan, Daniel M.

    2008-01-01

    Muon ionization cooling provides the only practical solution to prepare high-brilliance beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE), under development at the Rutherford Appleton Laboratory, is installing the first set of particle detectors ever built to measure to 0.1% the emittance of a 200 MeV/c or so muon beam in and out of a cooling cell, and thus measure the cooling cell's performance. Two identical "emittometers" (a precise scin...

  9. AFSC/NMML/CCEP: Natality rates of California sea lions at San Miguel Island, California during 1987-2008

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Mammal Laboratories' California Current Ecosystem Program (AFSC/NOAA) initiated a long-term marking program of California sea lions (Zalophus...

  10. AFSC/NMML/CCEP: Survival Rate of California sea lions at San Miguel Island, California from 1987-2009

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The dataset contains initial capture and marking data for California sea lion (Zalophus californianus) pups at San Miguel Island, California and subsequent...

  11. 78 FR 57101 - Walnuts Grown in California; Increased Assessment Rate

    Science.gov (United States)

    2013-09-17

    ... Agricultural Marketing Service 7 CFR Part 984 Walnuts Grown in California; Increased Assessment Rate AGENCY... assessment rate established for the California Walnut Board (Board) for the 2013-14 and subsequent marketing... administers the marketing order which regulates the handling of walnuts grown in California. Assessments...

  12. 78 FR 24979 - Olives Grown in California; Decreased Assessment Rate

    Science.gov (United States)

    2013-04-29

    ... Service 7 CFR Part 932 Olives Grown in California; Decreased Assessment Rate AGENCY: Agricultural... assessment rate established for the California Olive Committee (Committee) for the 2013 and subsequent fiscal... marketing order which regulates the handling of olives grown in California. Assessments upon olive...

  13. 76 FR 11937 - Olives Grown in California; Decreased Assessment Rate

    Science.gov (United States)

    2011-03-04

    ... Service 7 CFR Part 932 Olives Grown in California; Decreased Assessment Rate AGENCY: Agricultural... assessment rate established for the California Olive Committee (Committee) for 2011 and subsequent fiscal... order which regulates the handling of olives grown in California. Assessments upon olive handlers...

  14. Pathways for School Finance in California. Technical Appendix

    Science.gov (United States)

    Rose, Heather; Sonstelie, Jon; Weston, Margaret

    2010-01-01

    This is a technical appendix for the report, "Pathways for School Finance in California" (ED515651). "Pathways for School Finance in California" simulates alternatives to California's current school finance system. This appendix provides more information about the revenues used in those simulations. The first section describes the districts and…

  15. 78 FR 77367 - Almonds Grown in California; Continuance Referendum

    Science.gov (United States)

    2013-12-23

    ... Agricultural Marketing Service 7 CFR Part 981 Almonds Grown in California; Continuance Referendum AGENCY... referendum be conducted among eligible growers of almonds in California to determine whether they favor continuance of the marketing order that regulates the handling of almonds grown in California. DATES:...

  16. Electric energy demand and supply prospects for California

    Science.gov (United States)

    Jones, H. G. M.

    1978-01-01

    A recent history of electricity forecasting in California is given. Dealing with forecasts and regulatory uncertainty is discussed. Graphs are presented for: (1) Los Angeles Department of Water and Power and Pacific Gas and Electric present and projected reserve margins; (2) California electricity peak demand forecast; and (3) California electricity production.

  17. California coast sablefish - Reproductive Life History Analysis of Sablefish Populations off the Washington and California Coasts

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sablefish (Anoplopoma fimbria) have a wide distribution along the Pacific coast, extending from Baja California to Alaska, the Bering Sea and through to the eastern...

  18. Effects of fragmentation on the spatial ecology of the California Kingsnake (Lampropeltis californiae)

    Science.gov (United States)

    Anguiano, Michael P.; Diffendorfer, James E.

    2015-01-01

    We investigated the spatial ecology of the California Kingsnake (Lampropeltis californiae) in unfragmented and fragmented habitat with varying patch sizes and degrees of exposure to urban edges. We radiotracked 34 Kingsnakes for up to 3 yr across four site types: interior areas of unfragmented ecological reserves, the urbanized edge of these reserves, large habitat fragments, and small habitat fragments. There was no relationship between California Kingsnake movements and the degree of exposure to urban edges and fragmentation. Home range size and movement patterns of Kingsnakes on edges and fragments resembled those in unfragmented sites. Average home-range size on each site type was smaller than the smallest fragment in which snakes were tracked. The persistence of California Kingsnakes in fragmented landscapes may be related directly to their small spatial movement patterns, home-range overlap, and ability to use urban edge habitat.

  19. The Challenge: Latinos in a Changing California. The Report of the University of California SCR 43 Task Force.

    Science.gov (United States)

    California Univ., Riverside. Consortium on Mexico and the United States.

    This document presents a report from a task force composed of scholars, professionals, and community leaders to the State of California and the University of California (UC) addressing issues affecting Latinos in California. The following major recommendations are discussed: (1) continuing research must be undertaken concerning dynamic changes and…

  20. The Southern California Twin Register at the University of Southern California: III

    OpenAIRE

    Baker, Laura A.; Tuvblad, Catherine; Wang, Pan; Gomez, Karina; Bezdjian, Serena; Niv, Sharon; Raine, Adrian

    2013-01-01

    The Southern California Twin Register at the University of Southern California (USC) was initiated in 1984 and continues to provide an important resource for studies investigating genetic and environmental influences on human behavior. This article provides an update on the current register and its potential for future twin studies using recruitment through school district databases and voter records. An overview is also provided for an ongoing longitudinal twin study investigating the develo...

  1. Impact of the California sea lion (Zalophus californianus) on salmon fisheries in Monterey Bay, California

    OpenAIRE

    Weise, Michael J; Harvey, James T.

    2005-01-01

    To assess the impact of California sea lions (Zalophus californianus) on salmon fisheries in the Monterey Bay region of California, the percentages of hooked fish taken by sea lions in commercial and recreational salmon fisheries were estimated from 1997 to 1999. Onboard surveys of sea lion interactions with the commercial and recreational f isheries and dockside interviews with fishermen after their return to port were conducted in the ports of Santa Cruz, Moss Landing, and Monterey. Appr...

  2. Two decades of cumulative impacts to survivorship of endangered California condors in California

    OpenAIRE

    Kelly, TR; Rideout, BA; Grantham, J; BRANDT, J; Burnett, LJ; Sorenson, KJ; George, D; Welch, A; D. Moen; Rasico, J; Johnson, M.; Battistone, C; Johnson, CK

    2015-01-01

    © 2015 Elsevier B.V. We investigated threats to the California condor (Gymnogyps californianus), a flagship endangered species, using individual data on survival during a 20. year period of intensive recovery efforts. Over the two decades of reintroductions, condors in California had an estimated median survival time of 7.8. years suggesting that 50% of condors are expected to survive in the wild long enough to contribute to recruitment. In general, annual mortality rates exceeded levels nece...

  3. Introduction: The California Top Two Primary

    OpenAIRE

    Sinclair, Betsy

    2015-01-01

    The essays in this special issue of the California Journal of Public Policy examine the empirical evidence for an effect of the top two primary early in its implementation. The essays examine whether voters and candidates are likely to overcome the hurdles necessary to produce more moderate, pragmatic representation. The bulk of the research reaches common conclusions from different approaches.

  4. Bathymetry--Offshore of Santa Barbara, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3281 presents data for the bathymetry and shaded-relief maps (see sheets 1, 2, SIM 3281) of the Offshore of Santa Barbara map area, California. The...

  5. Reading Achievement in California: Miracle or Mirage?

    Science.gov (United States)

    Ruddell, Robert B.; Williams, Arthur

    Reading achievement of elementary school children in California has been measured by several separate studies, not all of which appear to present compatible results. This study of three assessments contained in the Miller-Unruh Report analyzes their purposes, methods, results, and recommendations in an effort to produce some way to arrive at an…

  6. State of California: Resource-recovery profile

    Science.gov (United States)

    1983-01-01

    The municipal refuse-to-energy conversion projects in the State of California are identified and outlined. Technologies include: combustion systems, refuse-derived fuel systems, co-combustion, methane from landfill systems, and methane from wastewater systems. Also included is a brief legislative history and discussion of progress and problems relating to the waste-to-energy projects.

  7. Recent landscape change in California's Central Valley

    Science.gov (United States)

    Soulard, C. E.; Wilson, T. S.

    2012-12-01

    Long term monitoring of land use and land cover in California's intensively farmed Central Valley reveals several key physical and socioeconomic factors driving landscape change. As part of the USGS Land Cover Trends Project, we analyzed modern land-use/land-cover change for the California Central Valley ecoregion between 2000 and 2010, monitoring annual change between 2005 and 2010, while creating two new change intervals (2000-2005 and 2005-2010) to update the existing 27-year, interval-based analysis. Between 2000 and 2010, agricultural lands fluctuated due to changes in water allocations and emerging drought conditions, or were lost permanently to development (240 square km). Land-use pressure from agriculture and development also led to a decline in grasslands and shrublands across the region (280 square km). Overall, 400 square km of new developed lands were added in the first decade of the 21st century. From 2007 to 2010, development only expanded by 50 square km, coinciding with defaults in the banking system, the onset of historic foreclosure crisis in California and the global economic downturn. Our annual LULC change estimates capture landscape-level change in response to regional policy changes, climate, and fluctuations (e.g., growth or decline) in the national and global economy. The resulting change data provide insights into the drivers of landscape change in the California Central Valley and the combination of two consistent mapping efforts represents the first continuous, 37-year endeavor of its kind.

  8. Bases tratadas con cemento, en California

    Directory of Open Access Journals (Sweden)

    Chinchilla, M.

    1962-05-01

    Full Text Available El uso de bases tratadas con cemento para autopistas se inició en el Estado de California en 1938, empleándose para carreteras con determinadas condiciones de tráfico. Inicialmente, se especificó el uso obligatorio de plantas mezcladoras para asegurar el debido control de las proporciones adecuadas.

  9. Funding California Schools: The Revenue Limit System

    Science.gov (United States)

    Weston, Margaret

    2010-01-01

    Tax revenue flows to California's nearly 1,000 school districts through many different channels. According to the Governor's Committee on Education Excellence (2007), this system is so complex that the state cannot determine how revenues are distributed among school districts, and after reviewing a large number of academic studies in the Getting…

  10. California Digital Library in Twitter-Land

    Science.gov (United States)

    Starr, Joan

    2010-01-01

    In October 2009, California Digital Library (CDL), where the author serves as manager of strategic and project planning, jumped into the world of social networking by joining Twitter. From Twitter, the CDL staff publish the content of their monthly newsletter, "CDLINFO News," and also additional content created by CDL programs and individuals. In…

  11. Culture in Crisis: Cambodian Refugees in California.

    Science.gov (United States)

    Crystal, Eric

    This preliminary paper reviews the political and cultural history of the Cambodian refugees who have settled in large numbers in California communities. The kingdom of Cambodia was a major power in Southeast Asia from the ninth century A.D. until March 1970, and its Buddhist culture influenced the dance, music, architecture, and linguistic…

  12. Conditions of Education in California, 2008

    Science.gov (United States)

    Policy Analysis for California Education, PACE (NJ1), 2008

    2008-01-01

    In this edition of "Conditions of Education" six of the leading academic authorities on education policy in California address the key issues facing the state's education system, focusing their attention on critical indicators of current performance and on specific policy changes that would lead to sustained improvement. They identify benchmarks…

  13. Global climate change and California's water resources

    International Nuclear Information System (INIS)

    This chapter records the deliberations of a group of California water experts about answers to these and other questions related to the impact of global warming on California's water resources. For the most part, those participating in the deliberations believe that the current state of scientific knowledge about global warming and its impacts on water resources is insufficient to permit hard distinctions to be made between short- and long-term changes. consequently, the ideas discussed here are based on a number of assumptions about specific climatic manifestations of global warming in California, as described earlier in this volume. Ultimately, however, effective public responses to forestall the potentially costly impacts of global climate change will probably depend upon the credible validation of the prospects of global climate warming. This chapter contains several sections. First, the likely effects of global warming on California's water resources and water-supply systems are identified and analyzed. Second, possible responses to mitigate these effects are enumerated and discussed. Third, the major policy issues are identified. A final section lists recommendations for action and major needs for information

  14. 77 FR 58901 - California Disaster #CA-00190

    Science.gov (United States)

    2012-09-24

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION California Disaster CA-00190 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  15. 78 FR 60366 - California Disaster #CA-00212

    Science.gov (United States)

    2013-10-01

    ... ADMINISTRATION California Disaster CA-00212 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY...: 06/24/2014. ADDRESSES: Submit completed loan applications to: U.S. Small Business Administration... CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd Street...

  16. Faculty Internships in California Community Colleges.

    Science.gov (United States)

    Klein, Charlie; Peralez, Jose

    In response to a request from the Board of Governors, the California Community Colleges' Office of the Chancellor undertook a study to determine the extent and characteristics of faculty internship programs in system colleges. In April 1995, surveys were mailed to human resource directors and chief instructional officers at all 106 community…

  17. The electric power crisis in California

    International Nuclear Information System (INIS)

    The RTE Director analyses the California electric power crisis: the operating system and reasons of crisis. He shows the leakages of such a distribution system and explains the differences with the european and more specially french operation. (A.L.B.)

  18. California School Accounting Manual, 1988 Edition.

    Science.gov (United States)

    California State Dept. of Education, Sacramento.

    This report presents the procedure for the accounting methods employed by California school districts for income and expenditures in instructional and support programs. The report has seven parts: (1) an introduction to accounting in local educational agencies; (2) general and subsidiary ledger accounting; (3) revenues and other financing sources;…

  19. Mission Accretion in the California Community Colleges.

    Science.gov (United States)

    Gaskin, Lori L.

    This study examines mission accretion, or the process by which the mission of the community college has broadened over time, in California's community colleges. The historical community college emphasis on transfer, occupational and remedial education, and community service has expanded to include the nontraditional educational initiatives of…

  20. The California State University Early Assessment Program

    Science.gov (United States)

    Knudson, Ruth E.; Zitzer-Comfort, Carol; Quirk, Matthew; Alexander, Pia

    2008-01-01

    The California State University (CSU) requires entering freshmen to be proficient in English reading and writing, as demonstrated on proficiency measures. Currently, approximately 46 percent of incoming college freshmen need remediation in English reading and writing. To assist these students, CSU instituted an Early Assessment Program (EAP),…

  1. FPI Cohort Reports: California State University System

    Science.gov (United States)

    Quirk, Robert J.

    2013-01-01

    The California State University (CSU) system is the largest higher educational system in the United States. The system has physical assets valued at more than $20 billion (current replacement value) on the "State" side of the house alone. With over 1,200 buildings, and 50 million square foot of mixed-use space, the CSU facility managers…

  2. Seafloor character--Offshore of Ventura, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of SIM 3254 presents data for the seafloor-character map (see sheet 7, SIM 3254) of the Offshore of Ventura map area, California. The raster data file is...

  3. California School Accounting Manual. 1984 Edition.

    Science.gov (United States)

    Lundin, Janet, Ed.

    California's official school accounting procedures, amended in 1984 to clarify definitions and improve program cost accounting, are presented. Following an introduction that discusses general characteristics of school accounting, the manual explains the following areas of accounting practice: (1) financial reporting; (2) income; (3) expenditures;…

  4. ERTS-1 applications to California resource inventory

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1972-01-01

    There are no author-identified significant results in this report. ERTS-1 information will be utilized by resource management groups working in the fields of forestry, hydrology, range management, and agriculture to develop resource inventories of the state of California. Five examples are given of the use of ERTS-1 imagery and aerial photography in identifying different crops and field conditions.

  5. Higher Education in California: Performance Budgeting

    Science.gov (United States)

    Murphy, Patrick; Cook, Kevin; Johnson, Hans; Weston, Margaret

    2014-01-01

    As California begins to reinvest in public higher education after several years of budget cuts, it could opt to tie funding more closely with outcomes--for example, the number of students educated or degrees awarded. This approach, known as performance-based funding, has the potential to incentivize investment by the state's higher education…

  6. Pb Isotopes Track Asian Pollution in California

    Science.gov (United States)

    Ewing, S. A.; Christensen, J. N.; Brown, S. T.; Vancuren, R. A.; Cliff, S. S.; Depaolo, D. J.

    2008-12-01

    The transport of Asian pollution to North America has broad implications for global climate models and regional air quality regulation. In the western US, rising atmospheric Pb levels have been evident since the mid-1990s despite the phase-out of leaded gasoline. We use Pb isotopes to fingerprint the trans-Pacific component of atmospheric pollution in California. We measured Pb isotopes in airborne particles collected at two sites west (Mt. Tamalpais) and east (Chabot Observatory, Oakland Hills) of the San Francisco Bay Area, from winter 2007 through late spring 2008. We also analyzed archived springtime samples from inland sites throughout central California. Wintertime values of 206Pb/207Pb vs. 208Pb/207Pb at Chabot Observatory form a linear array that is consistent with published data for San Francisco Bay waters, whereas published values for Chinese cities and loess fall along a separate and distinct array for that region, consistent with our analysis of samples collected at Hefei, China in 2002. Between March and May 2008, the Tamalpais and Chabot samples diverge from the California regional array toward the Chinese array. About half of the central California samples also show a strong Asian influence. We quantify the divergence of values from the regional California array as Δ208Pb = (208Pb/207Pb)expected - (208Pb/207Pb) )observed, where (208Pb/207Pb)expected is derived from a linear fit to the wintertime samples at Chabot Observatory. These Δ208Pb values increase between winter and spring at both Mt. Tamapais and Chabot Observatory, and are higher at Mt. Tamalpais, despite lower Pb concentrations at that site. They indicate that up to 80% of the Pb in the Tamalpais samples, and up to 40% of the Pb in the Chabot Observatory samples, reflect trans-Pacific transport. The lower proportion in the Chabot samples -- where there is often more Pb -- indicates dilution by local urban sources. Our data provide conclusive evidence of Asian air pollution reaching

  7. An integrated study of earth resources in the State of California based on Skylab and supporting aircraft data. [environmental monitoring, tectonics, ecology, and forest management in California

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1974-01-01

    Skylab data has been used: (1) as an aid to resource management in Northern California; (2) to assess and monitor change in the Southern California environment; and (3) for resource inventory and analysis of The California Desert Program.

  8. California Simulation of Evapotranspiration of Applied Water and Agricultural Energy Use in California

    Institute of Scientific and Technical Information of China (English)

    Morteza N Orang; Richard L Snyder; Shu Geng; Quinn J Hart; Sara Sarreshteh; Matthias Falk; Dylan Beaudette; Scott Hayes; Simon Eching

    2013-01-01

    The California Simulation of Evapotranspiration of Applied Water (Cal-SIMETAW) model is a new tool developed by the California Department of Water Resources and the University of California, Davis to perform daily soil water balance and determine crop evapotranspiration (ETc), evapotranspiration of applied water (ETaw), and applied water (AW) for use in California water resources planning. ETaw is a seasonal estimate of the water needed to irrigate a crop assuming 100%irrigation efficiency. The model accounts for soils, crop coefficients, rooting depths, seepage, etc. that influence crop water balance. It provides spatial soil and climate information and it uses historical crop and land-use category information to provide seasonal water balance estimates by combinations of detailed analysis unit and county (DAU/County) over California. The result is a large data base of ETc and ETaw that will be used to update information in the new California Water Plan (CWP). The application uses the daily climate data, i.e., maximum (Tx) and minimum (Tn) temperature and precipitation (Pcp), which were derived from monthly USDA-NRCS PRISM data (PRISM Group 2011) and daily US National Climate Data Center (NCDC) climate station data to cover California on a 4 km×4 km change grid spacing. The application uses daily weather data to determine reference evapotranspiration (ETo), using the Hargreaves-Samani (HS) equation (Hargreaves and Samani 1982, 1985). Because the HS equation is based on temperature only, ETo from the HS equation were compared with CIMIS ETo at the same locations using available CIMIS data to determine correction factors to estimate CIMIS ETo from the HS ETo to account for spatial climate differences. Cal-SIMETAW also employs near real-time reference evapotranspiration (ETo) information from Spatial CIMIS, which is a model that combines weather station data and remote sensing to provide a grid of ETo information. A second database containing the available soil

  9. Inborn anemias in mice

    International Nuclear Information System (INIS)

    hereditary anemias of mice have been the chief objects of investigation. At present under study are four macrocytic anemias, five hemolytic anemias, nonhemolytic microcytic anemia, transitory siderocytic anemia, sex-linked iron-transport anemia, an α-thalassemia, and a new target-cell anemia. Each of these blood dyscrasias is caused by the action of a unique mutant gene, which determines the structure of different intracellular molecules, and thus controls a different metabolic process. Thus our wide range of different hereditary anemias has considerable potential for uncovering many different aspects of hemopoietic homeostatic mechanisms in the mouse. Each anemia is studied through: (a) characterization of peripheral blood values, (b) determinations of radiosensitivity under a variety of conditions, (c) measurements of iron metabolism and heme synthesis, (d) histological and biochemical study of blood-forming tissue, (e) functional tests of the stem cell component, (f) examination of responses to erythroid stimuli, and (g) transplantation of tissue between individuals of differently affected genotypes

  10. Status of MICE

    CERN Document Server

    Bross, Alan D

    2008-01-01

    Muon ionization cooling is the only practical method for preparing high-brilliance beams needed for a neutrino factory or muon collider. The muon ionization cooling experiment (MICE) under development at the Rutherford Appleton Laboratory comprises a dedicated beamline to generate a range of input emittance and momentum, with time-of-flight and Cherenkov detectors to ensure a pure muon beam. A first measurement of emittance is performed in the upstream magnetic spectrometer with a scintillating-fiber tracker. A cooling cell will then follow, alternating energy loss in liquid hydrogen with RF acceleration. A second spectrometer identical to the first and a particle identification system will measure the outgoing emittance. Plans for measurements of emittance and cooling are described.

  11. Emittance Measurement in MICE

    CERN Document Server

    Hart, Terrence L

    2008-01-01

    Muon ionization cooling provides the only practical solution to prepare high-brilliance beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE), under development at the Rutherford Appleton Laboratory, is installing the first set of particle detectors ever built to measure to 0.1% the emittance of a 200 MeV/c or so muon beam in and out of a cooling cell, and thus measure the cooling cell's performance. Two identical "emittometers" (a precise scintillating-fiber tracker in solenoidal magnetic field and a 50 ps time-of-flight station) measure the six phase-space coordinates of each muon. Another TOF plane and two Cherenkov counters assure the purity of the incoming muon beam. A downstream electron/muon calorimeter eliminates contamination from decay electrons.

  12. Correlates of microhabitat use and density of Clethrionomys gapperi and Peromyscus keeni in temperate rain forests of Southeast Alaska%阿拉斯加东南部温带雨林加氏(鼠平)和肯氏鹿鼠密度与微生境利用的相关性

    Institute of Scientific and Technical Information of China (English)

    Winston P. SMITH; Scott M. GENDE; Jeffrey V. NICHOLS

    2005-01-01

    为了验证对阿拉斯加东南部温带雨林中有关栖息地关系的预测,我们于1999年和2000年8-9月以及1999年和2000年4-5月研究了亚历山大群岛加氏(鼠平)(Clethrionomys gapperi)和肯氏鹿鼠(Peromyscus keeni)种群.我们测量了26个植被和结构特征以检验林隙老龄生长林、多时代老龄生长林、采伐前壮龄(23岁)生长林和泥炭混交针叶林的丰富度与微栖息地利用的相关性.微栖息地利用随季节和栖息地而变化,但加氏(鼠平)与林下落叶灌木覆盖度的正相关最显著.肯氏鹿鼠利用的微环境的林地有较少的苔藓,但是林隙与抓获加氏(鼠平)的概率有直接关系.两种鼠在两个季节的密度与林下腐朽的倒木直接相关.春季的肯氏鹿鼠密度说明加氏(鼠平)密度变化的62%,说明肯氏鹿鼠密度变化的89%.我们的结果印证了早期对阿拉斯加东南部肯氏鹿鼠在各种栖息地尤其早期的演替林中兴旺时的研究;但偏离了西部地貌中肯氏鹿鼠种群在晚期演替针叶林中达到最高密度的普遍结论.与北美西北部其它地区的种群不同,加氏(鼠平)能持久生活在上层被砍伐的雨林板块中.泥炭针叶混交林对两种鼠的繁殖种群几乎没有贡献,因而不可能减轻对多产的老龄生长雨林大规模皆伐所造成的影响.%We studied red-backed vole Clethrionomys gapperi and Keen's mouse Peromyscus keeni populations in the Alexander Archipelago to test predictions regarding habitat relations in temperate rain forest of southeastern Alaska during August-September 1998 and 2000 and April-May 1999 and 2000. We measured 26 vegetative and structural features to correlate abundance among and microhabitat use within gap-phase old growth, multi-cohort old growth, pre-commercially thinned young (23-yr-old) growth, and peatland mixed-conifer forests. Populations of both species were higher in 1998 than 1999 and 2000. Both species used microhabitats randomly in

  13. Retrofit California Overview and Final Reports

    Energy Technology Data Exchange (ETDEWEB)

    Choy, Howard; Rosales, Ana

    2014-03-01

    Energy efficiency retrofits (also called upgrades) are widely recognized as a critical component to achieving energy savings in the building sector to help lower greenhouse gas (GHG) emissions. To date, however, upgrades have accounted for only a small percentage of aggregate energy savings in building stock, both in California and nationally. Although the measures and technologies to retrofit a building to become energy efficient are readily deployed, establishing this model as a standard practice remains elusive. Retrofit California sought to develop and test new program models to increase participation in the energy upgrade market in California. The Program encompassed 24 pilot projects, conducted between 2010 and mid-2013 and funded through a $30 million American Recovery and Reinvestment Act (ARRA) grant from the U.S. Department of Energy’s (DOE) Better Buildings Neighborhood Program (BBNP). The broad scope of the Program can be seen in the involvement of the following regionally based Grant Partners: Los Angeles County (as prime grantee); Association of Bay Area Governments (ABAG), consisting of: o StopWaste.org for Alameda County o Regional Climate Protection Authority (RCPA) for Sonoma County o SF Environment for the City and County of San Francisco o City of San Jose; California Center for Sustainable Energy (CCSE) for the San Diego region; Sacramento Municipal Utilities District (SMUD). Within these jurisdictions, nine different types of pilots were tested with the common goal of identifying, informing, and educating the people most likely to undertake energy upgrades (both homeowners and contractors), and to provide them with incentives and resources to facilitate the process. Despite its limited duration, Retrofit California undoubtedly succeeded in increasing awareness and education among home and property owners, as well as contractors, realtors, and community leaders. However, program results indicate that a longer timeframe will be needed to

  14. Scientific Insights for Managing Droughts in California

    Science.gov (United States)

    Lund, J. R.; Medellin-Azuara, J.; Howitt, R. E.; MacEwan, D.; Sumner, D. A.

    2015-12-01

    Droughts stress water systems and provide important opportunities to learn about vulnerabilities and motivate improvements in water systems. Current and past droughts in California show that this highly-engineered system is highly robust and resilient to droughts, as agriculture and urban water needs are mostly fulfilled and recover quickly following drought. However, environmental systems remain highly vulnerable and have shown less resilience to drought, with each drought bringing additional native species closer to extinction, often with little recovery following the drought. This paper reviews the impacts of California's ongoing 4-year drought and its importance for better understanding its ecological and water supply systems, as well as motivating improvements in water management and scientific work.

  15. Analysis of a California Catalina eddy event

    Science.gov (United States)

    Bosart, L. F.

    1983-01-01

    During the period 26-29 May 1968 a shallow cyclonic circulation, known locally as a Catalina eddy, developed in the offshore waters of southern California. A synoptic and mesoscale analysis of the event establishes the following: (1) the incipient circulation forms on the coast near Santa Barbara downwind of the coastal mountains, (2) cyclonic shear vorticity appears offshore in response to lee troughing downstream of the coastal mountains between Vandenberg and Pt. Mugu, California, (3) mountain wave activity may be aiding incipient eddy formation in association with synoptic-scale subsidence and the generation of a stable layer near the crest of the coastal mountains, (4) a southeastward displacement and offshore expansion of the circulation occurs following the passage of the synoptic-scale ridge line, and (5) dissipation of the eddy occurs with the onset of a broad onshore flow.

  16. Global climate change and California's natural ecosystems

    International Nuclear Information System (INIS)

    If projections of global climate models are correct, the natural ecosystems of California might undergo major changes during the next century. Such changes might include large economic losses in timber, fisheries, and recreation; major changes in our national and state parks and forests and in our nature preserves and conservation areas; increase in extinction of endangered species; loss of large areas of existing habitats; and development of new habitats whose location and areal extent can only be surmised. Many areas currently set aside for the conservation of specific ecosystems might no longer be suitable to them. Yet, in spite of the potential seriousness of these problems, which could dwarf all other environmental changes, California is at present in a poor situation to project what the effects of global change on its natural ecosystems might be

  17. Interpretation of Recent Temperature Trends in California

    Energy Technology Data Exchange (ETDEWEB)

    Duffy, P B; Bonfils, C; Lobell, D

    2007-09-21

    Regional-scale climate change and associated societal impacts result from large-scale (e.g. well-mixed greenhouse gases) and more local (e.g. land-use change) 'forcing' (perturbing) agents. It is essential to understand these forcings and climate responses to them, in order to predict future climate and societal impacts. California is a fine example of the complex effects of multiple climate forcings. The State's natural climate is diverse, highly variable, and strongly influenced by ENSO. Humans are perturbing this complex system through urbanization, irrigation, and emission of multiple types of aerosols and greenhouse gases. Despite better-than-average observational coverage, we are only beginning to understand the manifestations of these forcings in California's temperature record.

  18. Marine protected area networks in California, USA.

    Science.gov (United States)

    Botsford, Louis W; White, J Wilson; Carr, Mark H; Caselle, Jennifer E

    2014-01-01

    California responded to concerns about overfishing in the 1990s by implementing a network of marine protected areas (MPAs) through two science-based decision-making processes. The first process focused on the Channel Islands, and the second addressed California's entire coastline, pursuant to the state's Marine Life Protection Act (MLPA). We review the interaction between science and policy in both processes, and lessons learned. For the Channel Islands, scientists controversially recommended setting aside 30-50% of coastline to protect marine ecosystems. For the MLPA, MPAs were intended to be ecologically connected in a network, so design guidelines included minimum size and maximum spacing of MPAs (based roughly on fish movement rates), an approach that also implicitly specified a minimum fraction of the coastline to be protected. As MPA science developed during the California processes, spatial population models were constructed to quantify how MPAs were affected by adult fish movement and larval dispersal, i.e., how population persistence within MPA networks depended on fishing outside the MPAs, and how fishery yields could either increase or decrease with MPA implementation, depending on fishery management. These newer quantitative methods added to, but did not supplant, the initial rule-of-thumb guidelines. In the future, similar spatial population models will allow more comprehensive evaluation of the integrated effects of MPAs and conventional fisheries management. By 2011, California had implemented 132 MPAs covering more than 15% of its coastline, and now stands on the threshold of the most challenging step in this effort: monitoring and adaptive management to ensure ecosystem sustainability. PMID:25358301

  19. Decision framework for platform decommissioning in California.

    Science.gov (United States)

    Bernstein, Brock B

    2015-10-01

    This article describes the overall decision framework for eventual decisions about decommissioning the 27 operating oil and gas platforms offshore southern California. These platforms will eventually reach the end of their useful lifetimes (estimated between 2015 and 2030, although specific dates have not been determined). Current law and regulations allow for alternative uses in lieu of the complete removal required in existing leases. To prepare for eventual decommissioning, the California Natural Resources Agency initiated an in-depth process to identify and investigate issues surrounding possible decommissioning alternatives. The detailed evaluation of alternatives focused on 2-complete removal and artificial reefing that included partial removal to 85 feet below the waterline. These were selected after a comparison of the technical and economic feasibility of several potential alternatives, availability of a legal framework for implementation, degree of interest from proponents, and relative acceptance by state and federal decision makers. Despite California's history of offshore oil and gas production, only 7 decommissioning projects have been completed and these were all relatively small and close to shore. In contrast, nearly 30% of the California platforms are in water depths (as much as 1200 feet) that exceed any decommissioning project anywhere in the world. Most earlier projects considered an artificial reefing alternative but none were implemented and all platforms were completely removed. Future decisions about decommissioning must grapple with a more complex decision context involving greater technological and logistical challenges and cost, a wider range of viable options, tradeoffs among environmental impacts and benefits, and an intricate maze of laws, regulations, and authorities. The specific engineering differences between complete and partial removal provide an explicit basis for a thorough evaluation of their respective impacts. PMID:26259879

  20. Scale Interaction in a California precipitation event

    Energy Technology Data Exchange (ETDEWEB)

    Leach, M. J., LLNL

    1997-09-01

    Heavy rains and severe flooding frequently plaque California. The heavy rains are most often associated with large scale cyclonic and frontal systems, where large scale dynamics and large moisture influx from the tropical Pacific interact. however, the complex topography along the west coast also interacts with the large scale influences, producing local areas with heavier precipitation. In this paper, we look at some of the local interactions with the large scale.

  1. Renewable Hydrogen From Wind in California

    OpenAIRE

    Bartholomy, Obadiah

    2005-01-01

    Proceedings of the National Hydrogen Association Annual Hydrogen Conference (NHA 2005), Washington, DC, March 29 - April 1, 2005 Hydrogen produced from renewable electricity sources is frequently touted as the long-term goal for the hydrogen economy. The purpose of this paper is to examine the technical and economic realities of using wind power to produce hydrogen on a large scale in the state of California. Because of the relatively clean electricity grid, and its work on developme...

  2. Wind energy development in California, USA

    Science.gov (United States)

    Wilshire, H.; Prose, D.

    1987-01-01

    Windfarms have been developed rapidly in California in the last few years. The impetus has been a legislated goal to generate 10% of California's electricity by windpower by the year 2000, and generous state and federal tax incentives. Windpower is promoted as environmentally benign, which it is in traditional uses. The California program, however, is not traditional: it calls for centralized development of a magnitude sufficient to offset significant amounts of fossil fuels now used to generate electricity. Centralized windfarm development, as exemplified by the Altamont Pass, Tehachapi Mountains, and San Gorgonio Pass developments, involves major road building projects in erosion-sensitive terrain, effective closure of public lands, and other detrimental effects. A windfarm consisting of 200 turbines with 17-m rotors located in steep terrain 16 km from an existing corridor might occupy 235 ha and physically disturb 86 ha. With average annual wind speeds of 22.5 km/h, the farm would generate about 10??106 kWh/year at present levels of capacity. This annual production would offset 1% of one day's consumption of oil in California. To supply 10% of the state's electricity (at 1984 production rates) would require about 600,000 turbines of the type in common use today and would occupy more than 685,000 ha. It is likely that indirect effects would be felt in much larger areas and would include increased air and water pollution resulting from accelerated erosion, degradation of habitat of domestic and wild animals, damage to archaeological sites, and reduction of scenic quality of now-remote areas of the state. ?? 1987 Springer-Verlag New York Inc.

  3. 40 CFR 81.405 - California.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false California. 81.405 Section 81.405 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF...-58 USDA-FS Yolla-Bolly-Middle-Eel Wild 109,091 88-577 USDA-FS Yosemite NP 759,172 58-49 USDI-NPS 1...

  4. Cryptosporidium Species in Coastal California Ecosystems

    OpenAIRE

    Miller, Woutrina A.

    2004-01-01

    Cryptosporidium spp. are protozoan parasites that cause gastrointestinal disease in humans and animals, and are spread directly by fecal-oral transmission or indirectly by fecal contamination of water and food supplies. In California, there is evidence of significant fecal pathogen pollution flowing from terrestrial to aquatic ecosystems along the coast. To develop ecosystem monitoring and management strategies, we tested the hypothesis that Cryptosporidium spp. are detectable in nearsho...

  5. Cryptococcus gattii in AIDS Patients, Southern California

    OpenAIRE

    Chaturvedi, Sudha; Dyavaiah, Madhu; Larsen, Robert A.; Chaturvedi, Vishnu

    2005-01-01

    Cryptococcus isolates from AIDS patients in southern California were characterized by molecular analyses. Pheromone MFα1 and MF a 1 gene fragments were polymerase chain reaction–amplified with fluorescently labeled primers and analyzed by capillary electrophoresis (CE) on DNA analyzer. CE–fragment-length analyses (CE-FLAs) and CE–single-strand conformation polymorphisms (CE-SSCPs) were used to determine Cryptococcus gattii (Cg), C. neoformans (Cn) varieties neoformans (CnVN) and grubii (CnVG)...

  6. California Natural Gas Pipelines: A Brief Guide

    Energy Technology Data Exchange (ETDEWEB)

    Neuscamman, Stephanie [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Price, Don [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pezzola, Genny [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glascoe, Lee [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-01-22

    The purpose of this document is to familiarize the reader with the general configuration and operation of the natural gas pipelines in California and to discuss potential LLNL contributions that would support the Partnership for the 21st Century collaboration. First, pipeline infrastructure will be reviewed. Then, recent pipeline events will be examined. Selected current pipeline industry research will be summarized. Finally, industry acronyms are listed for reference.

  7. Bats in Agroecosytems around California's Central Coast

    Science.gov (United States)

    Wayne, A.

    2014-12-01

    Bats in agroecosystems around California's Central Coast: A full quarter of California's land area is farmland. Crops account for 32.5 billion of California's GDP. Insect control is a big problem for farmers, and California bats eat only insects, saving farmers an estimated 3 to $53 billion a year. As farmers maximize crop yield, they use more pesticides, herbicides, and fertilizers, which contaminate runoff streams that bats drink from. Also, pesticide use kills bats' sole food source: insects. My research objective was to find out how farm management practices and landscape complexity affect bat diversity and activity, and to see which one affects bat activity more. We monitored 18 sites, including conventional, organic, and low and high-complexity landscapes. We noted more bat activity at sites with high complexity landscapes and organic practices than at sites with either low-complexity landscapes or conventional farming practices. I captured and processed bats and recorded data. I also classified insects collected from light traps. I learned how to handle bats and measure forearm length and weight, as well as how to indentify their gender. I took hair clippings and fecal samples, which yield data about the bats' diet. Their diet, in turn, gives us data about which pests they eat and therefore help control. I also learned about bats' echolocation: they have a special muscle over their ears that closes when they echolocate so that they don't burst their own eardrum. Also, some insects have evolved a special call that will disrupt bats echolocation so bats can't track it.

  8. Competitive Dynamics of Southern California's Clothing Industry

    OpenAIRE

    Allen J. Scott

    2005-01-01

    A general outline of the functional and spatial characteristics of the clothing industry in Southern California is sketched out. Two important trends are noted: (a) the increasing design- and knowledge-intensive structure of the industry and (b) the marked increase in offshore subcontracting by local manufacturers that has occurred in recent years. The predicaments and promises of this situation are explored. Will the industry simply continue to lose its employment base in the region? Will it...

  9. Southern California: The Detroit of Electric Cars?

    OpenAIRE

    Allen J. Scott

    1993-01-01

    The California economy is in the doldrums, especially in the Los Angeles region, owing in large part to the decline of aerospace-defense industries. The region also suffers from the nation's worst pollution problem, owing largely to its dependence on automobiles. So, we're led to ask whether these linked perils might be converted into a combined opportunity. We ask whether we might blunt both the environmental and the employment problems by building a new electric-vehicle industry in Southern...

  10. Learning in Baja California micro-enterprises

    OpenAIRE

    Michelle Texis Flores; Alejandro Mungaray Lagarda; Martín Ramírez Urquidy; Natanael Ramírez Angulo

    2011-01-01

    Mexico’s business structure has been characterized by the presence of microenterprises, particularly those averaging two workers, representing 65% of establishments in 2008 and 18% of employment. This makes them important for equity and welfare improvement of their members. This paper analyzes the performance of a group of 227 microenterprises in the state of Baja California, by the use of a practical application of the concept of learning curve arranged to incorporate returns to scale. The r...

  11. Apolonia Dangzalan: Filipina Businesswoman, Watsonville, California

    OpenAIRE

    Regional History Project, UCSC Library; Dangzalan, Apolonia; Knaster, Meri; Reti, Irene

    2004-01-01

    Apolonia Dangzalan, a Filipino resident of Watsonville, California, was interviewed on April 27, 1977 by Meri Knaster, an editor at the Regional History Project, as part of a series of oral histories documenting local agricultural and ethnic history. Dangzalan was born in February 1896 in San Nicolas, Ilocos Sur, northwest of Manila, on the largest of the Philippine islands. Her family owned some land on which rice and corn was cultivated by sharecroppers. Her uncle was the president of San N...

  12. Storing Water in California's Hidden Reservoirs

    Science.gov (United States)

    Perrone, D.; Rohde, M. M.; Szeptycki, L.; Freyberg, D. L.

    2014-12-01

    California is experiencing one of its worst droughts in history; in early 2014, the Governor released the Water Action Plan outlining opportunities to secure reliable water supplies. Groundwater recharge and storage is suggested as an alternative to surface storage, but little research has been conducted to see if groundwater recharge is a competitive alternative to other water-supply infrastructure projects. Although groundwater recharge and storage data are not readily available, several voter-approved bonds have helped finance groundwater recharge and storage projects and can be used as a proxy for costs, geographic distribution, and interest in such projects. We mined and analyzed available grant applications submitted to the Department of Water Resources that include groundwater recharge and storage elements. We found that artificial recharge can be cheaper than other water-supply infrastructure, but the cost was dependent on the source of water, the availability and accessibility of infrastructure used to capture and convey water, and the method of recharge. Bond applications and funding awards were concentrated in the Central Valley and southern California - both are regions of high water demand. With less than 60% of proposals funded, there are opportunities for groundwater recharge and storage to play a bigger role in securing California's water supplies.

  13. California Basin Studies (CaBS)

    International Nuclear Information System (INIS)

    The California Continental Borderland's present configuration dates from about 4 to 5 X 106 years Before Present (B.P.) and is the most recent of several configurations of the southern California margin that have evolved after the North America Plate over-rode the East Pacific Rise about 30 X 106 years ago. The present morphology is a series of two to three northwest-southeast trending rows of depressions separated by banks and insular ridges. Two inner basins, Santa Monica and San Pedro, have been the site for the Department of Energy-funded California Basin Study (CaBS) Santa Monica and San Pedro Basins contain post-Miocene sediment thicknesses of about 2.5 and 1.5 km respectively. During the Holocene (past 10,000 years) about 10-12 m have accumulated. The sediment entered the basin by one or a combination of processes including particle infall (mainly as bioaggregates) from surface waters, from nepheloid plumes (surface, mid-depths and near-bottom), from turbidity currents, mass movements, and to a very minor degree direct precipitation. In Santa Monica Basin, during the last century, particle infall and nepheloid plume transport have been the most common processes. The former dominates in the central basin floor in water depths from 900 to 945 m. where a characteristic silt-clay with a typical mean diameter of about 0.006 mm, phi standard deviation

  14. Mice, men and MHC supertypes

    DEFF Research Database (Denmark)

    Lundegaard, Claus

    2010-01-01

    vaccine formulations. Toxoplasma gondii, an intracellular parasite, causes severe neurologic and ocular disease in congenitally infected and immunocompromised individuals. No protective vaccine exists against human toxoplasmosis. However, studies with mice have revealed immunodominant cytotoxic T...

  15. Owls and larks in mice.

    Science.gov (United States)

    Pfeffer, Martina; Wicht, Helmut; von Gall, Charlotte; Korf, Horst-Werner

    2015-01-01

    Humans come in different chronotypes and, particularly, the late chronotype (the so-called owl) has been shown to be associated with several health risks. A number of studies show that laboratory mice also display various chronotypes. In mice as well as in humans, the chronotype shows correlations with the period length and rhythm stability. In addition, some mouse models for human diseases show alterations in their chronotypic behavior, which are comparable to those humans. Thus, analysis of the behavior of mice is a powerful tool to unravel the molecular and genetic background of the chronotype and the prevalence of risks and diseases that are associated with it. In this review, we summarize the correlation of chronotype with free-running period length and rhythm stability in inbred mouse strains, in mice with a compromised molecular clockwork, and in a mouse model for neurodegeneration. PMID:26029157

  16. Owls and larks in mice

    Directory of Open Access Journals (Sweden)

    Martina ePfeffer

    2015-05-01

    Full Text Available Humans come in different chronotypes and, particularly, the late chronotype (the so-called owl has been shown to be associated with a number of health risks. Recent studies indicate that laboratory mice also display various chronotypes. In mice as well as in humans, the chronotype shows correlations with the period length and rhythm stability. In addition, some mouse models for human diseases show alterations in their chronotypic behavior which are comparable to those humans. Thus, analysis of the behavior of mice is a powerful tool to unravel the molecular and genetic background of the chronotype and the prevalence of risks and diseases that are associated with it. In this review, we summarize the correlation of chronotype with free-running period length and rhythm stability in the most commonly used inbred mouse strains, in mice with a compromised molecular clockwork and in a mouse model for neurodegeneration.

  17. Tamoxifen administration to mice.

    Science.gov (United States)

    Whitfield, Jonathan; Littlewood, Trevor; Soucek, Laura

    2015-03-01

    The strategy of fusing a protein of interest to a hormone-binding domain (HBD) of a steroid hormone receptor allows fine control of the activity of the fused protein. Such fusion proteins are inactive in the absence of ligand, because they are complexed with a variety of intracellular polypeptides. Upon ligand binding, the receptor is released from its inhibitory complex and the fusion protein becomes functional. In the murine estrogen receptor (ER) fusion system, proteins are fused to the HBD of the ER. The system relies on the use of a mutant ER known as ER(TAM). Compared to the wild-type HBD, ER(TAM) has 1000-fold lower affinity for estrogen, yet remains responsive to activation by the synthetic steroid 4-hydroxytamoxifen (4-OHT). Because 4-OHT is expensive, animals can be treated with the cheaper precursor tamoxifen, which is converted into 4-OHT by a liver enzyme. Here we present an overview of the methods used to deliver tamoxifen to mice. The most used method is intraperitoneal injection, because the amount of administered compound can be better controlled, but delivery by oral gavage is also possible. For short-term and immediate-effect studies or when conversion of tamoxifen by the liver is to be avoided, 4-OHT can be used directly. PMID:25734062

  18. Stress inoculation modeled in mice

    OpenAIRE

    Brockhurst, J; Cheleuitte-Nieves, C; Buckmaster, C L; Schatzberg, A. F.; Lyons, D M

    2015-01-01

    Stress inoculation entails intermittent exposure to mildly stressful situations that present opportunities to learn, practice and improve coping in the context of exposure psychotherapies and resiliency training. Here we investigate behavioral and hormonal aspects of stress inoculation modeled in mice. Mice randomized to stress inoculation or a control treatment condition were assessed for corticosterone stress hormone responses and behavior during open-field, object-exploration and tail-susp...

  19. Transplacental Arsenic Carcinogenesis in Mice

    OpenAIRE

    Waalkes, Michael P.; Liu, Jie; Diwan, Bhalchandra A.

    2007-01-01

    Our work has focused on the carcinogenic effects of in utero arsenic exposure in mice. Our data show a short period of maternal exposure to inorganic arsenic in the drinking water is an effective, multi-tissue carcinogen in the adult offspring. These studies have been reproduced in three temporally separate studies using two different mouse strains. In these studies pregnant mice were treated with drinking water containing sodium arsenite at up to 85 ppm arsenic from day 8 to 18 of gestation,...

  20. AGONISTIC BEHAVIOR OF LABORATORY MICE

    OpenAIRE

    D. Cinghiţă; D. Stănescu

    2005-01-01

    In this work we study agonistic behavior of laboratory white mice when they are kept in captivity. For all this experimental work we used direct observation of mice, in small lists, because we need a reduced space to emphasize characteristics of agonistic behavior. Relations between members of the same species that live in organized groups are based in most cases on hierarchical structure. Relations between leader and subservient, decided by fighting, involve a thorough observation between i...

  1. Human Malaria in Immunocompromised Mice

    OpenAIRE

    Badell, Edgar; Oeuvray, Claude; Moreno, Alicia; Soe, Soe; Van Rooijen, Nico; Bouzidi, Ahmed; Druilhe, Pierre

    2000-01-01

    We have recently described that sustained Plasmodium falciparum growth could be obtained in immunodeficient mice. We now report the potential of this new mouse model by assaying the effect of the passive transfer of antibodies (Abs) which in humans have had a well-established effect. Our results show that the total African adult hyperimmune immunoglobulin Gs (HI-IgGs) strongly reduce P. falciparum parasitemia similarly to that reported in humans, but only when mice are concomitantly reconstit...

  2. Tuberculosis Susceptibility of Diabetic Mice

    OpenAIRE

    Martens, Gregory W.; Arikan, Meltem Cevik; Lee, Jinhee; Ren, Fucheng; Greiner, Dale; Kornfeld, Hardy

    2007-01-01

    Increased susceptibility to infections, including tuberculosis (TB), is a major cause of morbidity and mortality in patients with diabetes. Despite the clinical importance of this problem, little is known about how diabetes impairs protective immunity. We modeled this phenomenon by infecting acute (⩽ 1 mo) or chronic (⩾ 3 mo) diabetic mice with a low aerosol dose of Mycobacterium tuberculosis (Mtb) Erdman. Diabetes was induced by streptozotocin (STZ) treatment of C57BL/6 mice, while another m...

  3. Seismology program; California Division of Mines and Geology

    Science.gov (United States)

    Sherburne, R. W.

    1981-01-01

    The year 1980 marked the centennial of the California Division of Mines and Geology (CDMG) and a decade of the Division's involvement in seismology. Factors which contributed to the formation of a Seismology Group within CDMG included increased concerns for environmental and earthquake safety, interest in earthquake prediction, the 1971 San Fernando earthquake and the 1973 publication by CDMG of an urban geology master plan for California. Reasons to be concerned about California's earthquake problem are demonstrated by the accompanying table and the figures. Recent seismicity in California, the Southern California uplift reflecting changes in crustal strain, and other possible earthquake precursors have heightened concern among scientific and governmental groups about the possible occurrence of a major damaging earthquake )M>7) in California

  4. Potential Benefits of Commissioning California Homes

    Energy Technology Data Exchange (ETDEWEB)

    Matson, Nance; Wray, Craig; Walker, Iain; Sherman, Max

    2002-01-01

    Commissioning California's houses can result in better performing systems and houses. In turn, this will result in more efficient use of energy, carbon emission reductions, and improved occupant comfort. In particular, commissioning houses can save a significant amount of HVAC-related energy (15 to 30% in existing houses, 10 to 20% in new conventional houses, and up to 8% in advanced energy efficiency houses). The process that we considered includes corrective measures that could be implemented together during construction or during a single site visit (e.g., air tightening, duct sealing, and refrigerant and air handler airflow corrections in a new or existing house). Taking advantage of additional, more complex opportunities (e.g., installing new windows in an existing house, replacing the heating and air conditioning system in a new or existing house) can result in additional HVAC-related energy savings (60 to 75% in existing houses, and 50 to 60% in new conventional houses). The commissioning-related system and house performance improvements and energy savings translate to additional benefits throughout California and beyond. By applying commissioning principles to their work, the building community (builders and contractors) benefit from reduced callbacks and lower warranty costs. HERS raters and inspectors will have access to an expanded market sector. As the commissioning process rectifies construction defects and code problems, building code officials benefit from better compliance with codes. The utilities benefit from reduced peak demand, which can translate into lower energy acquisition costs. As houses perform closer to expectations, governmental bodies (e.g., the California Energy Commission and the Air Resources Board) benefit from greater assurance that actual energy consumption and carbon emissions are closer to the levels mandated in codes and standards, resulting in better achievement of state energy conservation and environmental goals

  5. Advanced Planning for Tsunamis in California

    Science.gov (United States)

    Miller, K.; Wilson, R. I.; Larkin, D.; Reade, S.; Carnathan, D.; Davis, M.; Nicolini, T.; Johnson, L.; Boldt, E.; Tardy, A.

    2013-12-01

    The California Tsunami Program is comprised of the California Governor's Office of Emergency Services (CalOES) and the California Geological Survey (CGS) and funded through the National Tsunami Hazard Mitigation Program (NTHMP) and the Federal Emergency Management Agency (FEMA). The program works closely with the 20 coastal counties in California, as well as academic, and industry experts to improve tsunami preparedness and mitigation in shoreline communities. Inundation maps depicting 'worst case' inundation modeled from plausible sources around the Pacific were released in 2009 and have provided a foundation for public evacuation and emergency response planning in California. Experience during recent tsunamis impacting the state (Japan 2011, Chile 2010, Samoa 2009) has brought to light the desire by emergency managers and decision makers for even more detailed information ahead of future tsunamis. A solution to provide enhanced information has been development of 'playbooks' to plan for a variety of expected tsunami scenarios. Elevation 'playbook' lines can be useful for partial tsunami evacuations when enough information about forecast amplitude and arrival times is available to coastal communities and there is sufficient time to make more educated decisions about who to evacuate for a given scenario or actual event. NOAA-issued Tsunami Alert Bulletins received in advance of a distant event will contain an expected wave height (a number) for each given section of coast. Provision of four elevation lines for possible inundation enables planning for different evacuation scenarios based on the above number potentially alleviating the need for an 'all or nothing' decision with regard to evacuation. Additionally an analytical tool called FASTER is being developed to integrate storm, tides, modeling errors, and local tsunami run-up potential with the forecasted tsunami amplitudes in real-time when a tsunami Alert is sent out. Both of these products will help

  6. Miwok Dancers of 1856: Stereographic Images from Sonora, California

    OpenAIRE

    Bates, Craig D

    1984-01-01

    Five stereographic views of Miwok people (Figs. 1-5) made in Sonora, California, during the 1850s are apparently the earliest photographic representations of Sierra Miwok people, and perhaps the earliest such images of any Indian people in northern California. Primarily showing individuals in ceremonial regalia, these photographs provide us with an unparalleled view of California Indians at the end of the Gold Rush period in the Mother Lode region of the Sierra Nevada.

  7. Services Export Opportunities for California -- A Preliminary Assessment

    OpenAIRE

    Bardhan, Ashok; Kroll, Cynthia A.

    2006-01-01

    In the age of offshoring, rising imports, and job loss concerns, it is vital to formulate strategies for export promotion. This paper identifies, examines and analyzes export opportunities for small and medium sized California services firms (SMEs), which employ the majority of California workers. The research assesses trends in services exports, characteristics of the California economy and of small (fewer than 100 employees) and medium-sized firms (100 to 500 employees), resources available...

  8. Correlates of Plant Biodiversity in Mediterranean Baja California, Mexico.

    OpenAIRE

    Vanderplank, Sula Elizabeth

    2013-01-01

    Northwestern Baja California is an area of exceptionally high local endemism, nestled at the southernmost end of the California Floristic Province (CFP), one of the world's mediterranean-climate regions. The ecotonal position between the CFP and the central deserts of the Baja California Peninsula reflects the transition of the major climatic regimes. This area appears to have been more climatically stable than adjacent areas, and the local endemism along the coast is largely the result of th...

  9. Stinkwort is rapidly expanding its range in California

    OpenAIRE

    Brownsey, Rachel; Kyser, Guy B; DiTomaso, Joseph M.

    2013-01-01

    Stinkwort (Dittrichia graveolens) is a Mediterranean native that has become a weed in areas of Europe as well as in Australia. This strongly aromatic weed was first reported in California in 1984 in Santa Clara County, and it had spread to 36 of the 58 California counties by 2012. Stinkwort is not palatable to animals, and can be poisonous to livestock and cause contact allergic dermatitis in humans. In California, this weed is found primarily along roadsides. However, the biology of t...

  10. Thou shalt speak English: English in California elections

    OpenAIRE

    Thompson, Bozena Henisz

    1987-01-01

    In this paper I present the results of a study of attitudes towards an issue of language policy in California. A proposition was put on the November 4, 1986 general election ballot to make English the official state language of California (called Proposition 63). As the preelection polls indicated, the proposition passed, thus becoming law, by a vote of three-fourths of those voting. This issue is particularly sensitive in California, where the predictions are that by the year ...

  11. Families in the making: gestational surrogate mothers in California

    OpenAIRE

    Bjørn, Henriette Hårseide

    2014-01-01

    This thesis is based on a field work I conducted in California from January to June 2012, where I explore how gestational surrogate mothers experience the process of surrogacy and how California law has dealt with ART-cases. Through exploring surrogacy from different view point, and in particular from the view of surrogate mothers, this has given an insightful view into surrogacy in California. I have identified two court cases which are important for the establishment of parental rights in s...

  12. Restructuring and renewable energy developments in California: using Elfin to simulate the future California power market

    International Nuclear Information System (INIS)

    We provide some basic background information on support for renewable in California on the expected operation of the power pool and bilateral markets, and on the three key policy types modeled here. We discuss the Elfin production cost and expansion planning model as well as key assumptions that we made to model the future California pool. We present results from the successful Elfin models runs. We discuss the implications of the study, as well as key areas for future research. Additional information on results, Elfin's expansion planning logic, and resource options can be found in the appendices

  13. Detection and characterization of diverse coccidian protozoa shed by California sea lions.

    Science.gov (United States)

    Girard, Yvette A; Johnson, Christine K; Fritz, Heather M; Shapiro, Karen; Packham, Andrea E; Melli, Ann C; Carlson-Bremer, Daphne; Gulland, Frances M; Rejmanek, Daniel; Conrad, Patricia A

    2016-04-01

    Tissue-cyst forming coccidia in the family Sarcocystidae are etiologic agents of protozoal encephalitis in marine mammals including the federally listed Southern sea otter (Enhydra lutris). California sea lions (Zalophus californianus), whose coastal habitat overlaps with sea otters, are definitive hosts for coccidian protozoa provisionally named Coccidia A, B and C. While Coccidia A and B have unknown clinical effects on aquatic wildlife hosts, Coccidia C is associated with severe protozoal disease in harbor seals (Phoca vitulina). In this study, we conducted surveillance for protozoal infection and fecal shedding in hospitalized and free-ranging California sea lions on the Pacific Coast and examined oocyst morphology and phenotypic characteristics of isolates via mouse bioassay and cell culture. Coccidia A and B were shed in similar frequency, particularly by yearlings. Oocysts shed by one free-ranging sea lion sampled at Año Nuevo State Park in California were previously unidentified in sea lions and were most similar to coccidia infecting Guadalupe fur seals (Arctocephalus townsendi) diagnosed with protozoal disease in Oregon (USA). Sporulated Coccidia A and B oocysts did not replicate in three strains of mice or in African green monkey kidney cells. However, cultivation experiments revealed that the inoculum of fecally-derived Coccidia A and B oocysts additionally contained organisms with genetic and antigenic similarity to Sarcocystis neurona; despite the absence of detectable free sporocysts in fecal samples by microscopic examination. In addition to the further characterization of Coccidia A and B in free-ranging and hospitalized sea lions, these results provide evidence of a new role for sea lions as putative mechanical vectors of S. neurona, or S. neurona-like species. Future work is needed to clarify the distribution, taxonomical status, and pathogenesis of these parasites in sea lions and other marine mammals that share their the near-shore marine

  14. Detection and characterization of diverse coccidian protozoa shed by California sea lions

    Directory of Open Access Journals (Sweden)

    Yvette A. Girard

    2016-04-01

    Full Text Available Tissue-cyst forming coccidia in the family Sarcocystidae are etiologic agents of protozoal encephalitis in marine mammals including the federally listed Southern sea otter (Enhydra lutris. California sea lions (Zalophus californianus, whose coastal habitat overlaps with sea otters, are definitive hosts for coccidian protozoa provisionally named Coccidia A, B and C. While Coccidia A and B have unknown clinical effects on aquatic wildlife hosts, Coccidia C is associated with severe protozoal disease in harbor seals (Phoca vitulina. In this study, we conducted surveillance for protozoal infection and fecal shedding in hospitalized and free-ranging California sea lions on the Pacific Coast and examined oocyst morphology and phenotypic characteristics of isolates via mouse bioassay and cell culture. Coccidia A and B were shed in similar frequency, particularly by yearlings. Oocysts shed by one free-ranging sea lion sampled at Año Nuevo State Park in California were previously unidentified in sea lions and were most similar to coccidia infecting Guadalupe fur seals (Arctocephalus townsendi diagnosed with protozoal disease in Oregon (USA. Sporulated Coccidia A and B oocysts did not replicate in three strains of mice or in African green monkey kidney cells. However, cultivation experiments revealed that the inoculum of fecally-derived Coccidia A and B oocysts additionally contained organisms with genetic and antigenic similarity to Sarcocystis neurona; despite the absence of detectable free sporocysts in fecal samples by microscopic examination. In addition to the further characterization of Coccidia A and B in free-ranging and hospitalized sea lions, these results provide evidence of a new role for sea lions as putative mechanical vectors of S. neurona, or S. neurona-like species. Future work is needed to clarify the distribution, taxonomical status, and pathogenesis of these parasites in sea lions and other marine mammals that share their the near

  15. Smoking-attributable cancer mortality in California, 1979–2005

    OpenAIRE

    Cowling, David W; Yang, Juan

    2010-01-01

    Background The adult smoking prevalence has declined more in California than the rest of the US in the past 2 decades. Further, California has faster declines in cancer mortality, lung cancer incidence and heart disease mortality. However, no study has examined smoking-related cancer mortality between California and the rest of the US. Methods The smoking-attributable cancer mortality rate (SACMR) from 1979 to 2005 in California and the rest of the US are calculated among men and women 35 yea...

  16. California's 2002 Clean Water Act Section 303(d) - Impaired Streams and Rivers

    Data.gov (United States)

    California Department of Resources — This dataset contains California's 2002 Clean Water Act Section 303(d) list which is submitted by the California State Water Resources Control Board. The layer has...

  17. 76 FR 14052 - Notice of Inventory Completion: California State University, Sacramento, Sacramento, CA

    Science.gov (United States)

    2011-03-15

    ... Collection, were donated to Sacramento State College (now California State University, Sacramento). No known... California State University, Sacramento, together with the University's College of Social Sciences and... National Park Service Notice of Inventory Completion: California State University, Sacramento,...

  18. 78 FR 43870 - Hydrogen Energy California's Integrated Gasification Combined Cycle Project; Preliminary Staff...

    Science.gov (United States)

    2013-07-22

    ... of Availability Hydrogen Energy California's Integrated Gasification Combined Cycle Project... availability of the Hydrogen Energy California's Integrated Gasification Combined Cycle Project Preliminary... the Hydrogen Energy California's (HECA) Integrated Gasification Combined Cycle Project, which would...

  19. Linkage disequilibrium in wild mice.

    Directory of Open Access Journals (Sweden)

    Cathy C Laurie

    2007-08-01

    Full Text Available Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causative genes have been identified. The main difficulty is the extensive linkage disequilibrium (LD in intercross progeny and the slow process of fine-scale mapping by traditional methods. Recently, new approaches have been introduced, such as association studies with inbred lines and multigenerational crosses. These approaches are very useful for interval reduction, but generally do not provide single-gene resolution because of strong LD extending over one to several megabases. Here, we investigate the genetic structure of a natural population of mice in Arizona to determine its suitability for fine-scale LD mapping and association studies. There are three main findings: (1 Arizona mice have a high level of genetic variation, which includes a large fraction of the sequence variation present in classical strains of laboratory mice; (2 they show clear evidence of local inbreeding but appear to lack stable population structure across the study area; and (3 LD decays with distance at a rate similar to human populations, which is considerably more rapid than in laboratory populations of mice. Strong associations in Arizona mice are limited primarily to markers less than 100 kb apart, which provides the possibility of fine-scale association mapping at the level of one or a few genes. Although other considerations, such as sample size requirements and marker discovery, are serious issues in the implementation of association studies, the genetic variation and LD results indicate that wild mice could provide a useful tool for identifying genes that cause variation in complex traits.

  20. Developing New Management Techniques for Sharks in the Drift Gillnet Fishery of the Southern California Bight

    OpenAIRE

    Graham, Jeffrey B.; Cartamil, Daniel P.

    2009-01-01

    The Southern California Bight (SCB) is a contiguous geographical region that extends from Point Conception, California to northern Baja California and west into the California Current. This region’s productive ecosystem supports various recreational and commercial fisheries, some of which target pelagic sharks. For example, the common thresher shark (Alopias vulpinus) comprises the largest commercial shark fishery in California waters (the California drift gillnet fishery, or CA-DGF. Mako sha...

  1. California Tribal Nations Technical Water Research

    Energy Technology Data Exchange (ETDEWEB)

    Ben, C; Coty, J

    2005-08-15

    This research focused on identifying the key technical water issues of federally recognized California Native American tribes, the context within which these water issues arise for the tribes, and an appropriate format for potentially opening further dialogue on water research issues between the tribes and Lawrence Livermore National Laboratory (LLNL) scientists. At LLNL, a Water Quality and Resource Management Issues Workshop held in January of 2003 resulted in multiple recommendations, one proposing a LLNL dialogue with California tribes to further inform LLNL's prioritization of water issues based on identified needs across national sectors. The focus of this aforementioned Water Quality and Resource Management Issues Workshop was to identify national and international priority water research issues with which LLNL may align their research efforts and contribute to resolving these needs. LLNL staff researched various sectors to delineate the key water issues associated with each. This preliminary water issue research included diverse entities such as international water agencies, federal and state agencies, industry, non-governmental agencies, and private organizations. The key (identified) water issues across these sectors were presented to workshop attendees and used during workshop debates and sessions. However, the key water issues of federally recognized Native American tribes remained less understood, resulting in a workshop proposal for additional research and LLNL potentially hosting a dialog with representatives of these tribes. Federally recognized Native American tribes have a unique government-to-government relationship with the United States (U.S.) government, in contrast to other sectors researched for the workshop. Within the U.S., the number of federally recognized tribes currently stands at 562 and, in addition to this large number of tribes, much diversity across these tribes exists. For the purposes of this preliminary research and report

  2. From California dreaming to California data: Challenging historic models for landfill CH4 emissions

    Science.gov (United States)

    Improved quantification of diverse CH4 sources at the urban scale is needed to guide local greenhouse gas (GHG) mitigation strategies in the Anthropocene. Herein, we focus on landfill CH4 emissions in California, challenging the current IPCC methodology which focuses on a climate dependency for land...

  3. The California Current system off Monterey, California: physical and biological coupling

    Science.gov (United States)

    Collins, C. A.; Pennington, J. T.; Castro, C. G.; Rago, T. A.; Chavez, F. P.

    2003-08-01

    Repeated hydrobiological surveys over the period 1988-2002 perpendicular to the central California coast indicate strong coupling between physical circulation and biological production. An equatorward-flowing jet about 100-200 km from shore marked the inshore edge of the California Current (CC). This "CC Jet" had its highest velocities during late winter and spring. The jet divided inshore, biologically productive waters from offshore, low-production waters. Mean flow in the inshore waters is poleward. However, this flow is interrupted in late spring and summer by a surface-enhanced, equatorward-flowing, coastal upwelling jet. The upwelling jet coincides with maxima of nutrients, chlorophyll- a and primary production. Annual variability in the inshore zone is related to (1) vertical pycnocline movements associated with geostrophic adjustments to accelerations of the California Current system, and (2) coastal upwelling. In offshore waters, the annual cycle accounted for a small fraction of the variability, indicating the dominance of eddies and meanders in this zone (J. Geophys. Res. 92 (1987) 12 947). The offshore regime was mesotrophic to oligotrophic, with a subsurface chlorophyll- a maximum above the nutricline. Considerable subduction may occur under the California Current jet and be an important process in the export of biogenic material to the deep sea.

  4. Learning from California and the Pacific Rim

    International Nuclear Information System (INIS)

    Heavy oils are found in 10 of the 14 largest oilfields in Alaska and California. In the US west coast region, petroleum demand is dominated by light transport fuels, and there is a lack of a discrete and conspicuous heavy oil market. The structure and behavior of west coast petroleum markets, and their interactions with crude-oil and petroleum product markets elsewhere on the Pacific Rim are discussed with regard to how the market for growing volumes of western Canadian heavy oils might evolve. An analysis of crude oil prices versus API gravity demonstrates the price penalties on oil of low gravity, high sulfur, and high transport cost. Prices at the high gravity end tend to correlate closely with Asian light crude and unfinished gasoline prices. The heaviest crudes are priced in competition with other chemically similar residual oils for direct fuel use, blending, or refinery feedstock. The biggest component of the west coast heavy oil market is bunker fuel. The market value of heavy crudes in the west coast is thus determined by regional supply and demand for heavy hydrocarbon molecules, whatever the source. The west coast is not a promising market for Canadian heavy crudes, and exports to Asia would have to compete both with residual oils from Asia and the US west coast and with California heavy crudes. US west coast production peaked in 1989 and regional production can be expected to decline further in average gravity. New production from known but undeveloped heavy oil pools near Prudhoe Bay or in the California offshore could be expected to postpone the need for imports to the west coast and to depress prices. A removal of the Alaska crude oil export ban could improve the west coast heavy oil market. 5 refs., 2 figs., 1 tab

  5. Practical pathology of aging mice

    Directory of Open Access Journals (Sweden)

    Piper M. M. Treuting

    2011-06-01

    Full Text Available Old mice will have a subset of lesions as part of the progressive decline in organ function that defines aging. External and palpable lesions will be noted by the research, husbandry, or veterinary staff during testing, cage changing, or physical exams. While these readily observable lesions may cause alarm, not all cause undue distress or are life-threatening. In aging research, mice are maintained until near end of life that, depending on strain and genetic manipulation, can be upwards of 33 months. Aging research has unique welfare issues related to age-related decline, debilitation, fragility, and associated pain of chronic diseases. An effective aging research program includes the collaboration and education of the research, husbandry, and veterinary staff, and of the members of the institution animal care and use committee. This collaborative effort is critical to humanely maintaining older mice and preventing excessive censorship due to non-lethal diseases. Part of the educational process is becoming familiar with how old mice appear clinically, at necropsy and histopathologically. This baseline knowledge is important in making the determination of humane end points, defining health span, contributing causes of death and effects of interventions. The goal of this paper is to introduce investigators to age-associated diseases and lesion patterns in mice from clinical presentation to pathologic assessment. To do so, we present and illustrate the common clinical appearances, necropsy and histopathological lesions seen in subsets of the aging colonies maintained at the University of Washington.

  6. H2 fuelling infrastructure in Southern California

    International Nuclear Information System (INIS)

    'Full text:' The South Coast Air Quality Management District (SCAQMD) is the local air agency covering the majority of southern California, and the entity legislatively responsible for bringing the region into compliance with the federal Clean Air standards by 2010. One of the tools used by the SCAQMD to accelerate achieving cleaner air is the funding of research, development, and demonstration projects for advanced, clean air technologies. One major focus has been on hydrogen and fuel cells for both stationary and mobile applications. The presentation will discuss the SCAQMD strategy and deployment efforts regarding the development and expansion of hydrogen fueling infrastructure in the South Coast Air Basin. (author)

  7. Implementing Risk-Limiting Audits in California

    OpenAIRE

    Hall, Joseph L.; Miratrix, Luke W.; Stark, Philip B.; Briones, Melvin; Ginnold, Elaine; Oakley, Freddie; Peaden, Martin; Pellerin, Gail; Stanionis, Tom; Webber, Tricia

    2009-01-01

    Risk-limiting post-election audits limit the chance of certifying an electoral outcome if the outcome is not what a full hand count would show. Building on previous work, we report on pilot risk-limiting audits in four elections during 2008 in three California counties: one during the February 2008 Primary Election in Marin County and three during the November 2008 General Elections in Marin, Santa Cruz and Yolo Counties. We explain what makes an audit risk-limiting and how existing and pro...

  8. Piezometer Performance at Wildlife Liquefaction Site, California

    OpenAIRE

    Scott, Ronald F.; Hushmand, B.

    1995-01-01

    In response to an urgent need for field data from instrumented liquefaction sites, the U.S. Geological Survey in 1982 selected and instrumented a site in southern California called the Wildlife site. Two accelerometers (one at ground surface and one at a depth of 7.5 m) and six electrical pore-pressure transducers (five in a liquefiable silty sand layer) were placed at the site. The November 1987 Superstition Hills earthquake triggered sand boils and the desired instrumental response by gener...

  9. MOSES AND DENNISON PEAK ROADLESS AREAS, CALIFORNIA.

    Science.gov (United States)

    Goldfarb, Richard J.; Lipton, David A.

    1984-01-01

    A mineral-resource survey was conducted in the Moses and Dennison Peak Roadless Areas, southeastern Sierra Nevada, California. One area within the Moses Roadless Area is classified as having substantiated mineral-resource potential for small base-metal skarn deposits. Additionally, geochemical data indicate probable potential for small base-metal skarn deposits from one locality within Dennison Peak Roadless Area and for small tungsten skarn deposits from a region within Moses Roadless Area. The geologic setting precludes the presence of energy resources.

  10. Misunderstood markets: The case of California gasoline

    Science.gov (United States)

    Thompson, Jennifer Ruth

    In 1996, the California Air Resources Board (CARB) implemented a new benchmark for cleaner burning gasoline that is unique to California. Since then, government officials have often expressed concern that the uniqueness of petroleum products in California segregates the industry, allowing for gasoline prices in the State that are too high and too volatile. The growing concern about the segmentation of the California markets lends itself to analysis of spatial pricing. Spatial price spreads of wholesale gasoline within the state exhibit some characteristics that seem, on the surface, inconsistent with spatial price theory. Particularly, some spatial price spreads of wholesale gasoline appear larger than accepted transportation rates and other spreads are negative, giving a price signal for transportation against the physical flow of product. Both characteristics suggest some limitation in the arbitrage process. Proprietary data, consisting of daily product prices for the years 2000 through 2002, disaggregated by company, product, grade, and location is used to examine more closely spatial price patterns. My discussion of institutional and physical infrastructure outlines two features of the industry that limit, but do not prohibit, arbitrage. First, a look into branding and wholesale contracting shows that contract terms, specifically branding agreements, reduces the price-responsiveness of would-be arbitrageurs. Second, review of maps and documents illustrating the layout of physical infrastructure, namely petroleum pipelines, confirms the existence of some connections among markets. My analysis of the day-of-the-week effects on wholesale prices demonstrates how the logistics of the use of transportation infrastructure affect market prices. Further examination of spatial price relationships shows that diesel prices follow closely the Augmented Law of One Price (ALOP), and that branding agreements cause gasoline prices to deviate substantially ALOP. Without branding

  11. Wind to Hydrogen in California: Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Antonia, O.; Saur, G.

    2012-08-01

    This analysis presents a case study in California for a large scale, standalone wind electrolysis site. This is a techno-economic analysis of the 40,000 kg/day renewable production of hydrogen and subsequent delivery by truck to a fueling station in the Los Angeles area. This quantity of hydrogen represents about 1% vehicle market penetration for a city such as Los Angeles (assuming 0.62 kg/day/vehicle and 0.69 vehicles/person) [8]. A wind site near the Mojave Desert was selected for proximity to the LA area where hydrogen refueling stations are already built.

  12. Progress of the MICE experiment

    CERN Document Server

    Bonesini, M

    2015-01-01

    The international Muon Ionization Cooling Experiment (MICE) will perform a systematic investigation of ionization cooling of a muon beam. The demonstration is based on a simplified version of a neutrino factory cooling channel. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation has been developed to measure particle coordinates and timing vs RF. The muon beamline has been characterized and a preliminary measure of the beam emittance, using a particle-by-particle method with only the TOF detector system, has been performed (MICE STEP I). Data taking for the study of the properties that determine the cooling performance (MICE Step IV) has just started in 2015, while the demonstration of ionization cooling with re-acceleration is foreseen for 2017.

  13. A Suggested Journalism Curriculum for California Junior Colleges.

    Science.gov (United States)

    Margosian, Arthur

    The purpose of this study was to develop a suggested journalism curriculum for California junior colleges, based upon the functions and content of journalism programs as they should be, as perceived by a representative group of junior college instructrs and editors of daily and weekly newspapers in California. Data were collected from…

  14. 78 FR 62959 - Kiwifruit Grown in California; Decreased Assessment Rate

    Science.gov (United States)

    2013-10-23

    ... Service 7 CFR Part 920 Kiwifruit Grown in California; Decreased Assessment Rate AGENCY: Agricultural... assessment rate established for the Kiwifruit Administrative Committee (Committee) for the 2013-14 and... in California. Assessments upon kiwifruit handlers are used by the Committee to fund reasonable...

  15. 76 FR 50703 - Walnuts Grown in California; Increased Assessment Rate

    Science.gov (United States)

    2011-08-16

    ...; Increased Assessment Rate AGENCY: Agricultural Marketing Service, USDA. ACTION: Proposed rule. SUMMARY: This rule would increase the assessment rate established for the California Walnut Board (Board) for the... in California. Assessments upon walnut handlers are used by the Board to fund reasonable...

  16. Professional Mathematicians Comment on School Mathematics in California.

    Science.gov (United States)

    Haimo, Deborah Tepper; Milgram, R. James

    2000-01-01

    Critiques Jerry Becker and Bill Jacob's article on the politics of California school mathematics in the March 2000 "Kappan" for characterizing current California standards as a return to the past. Mathematicians are apolitical, but must coordinate K-12 curriculum frameworks with college-level math courses. (MLH)

  17. Graduate Fees at California's Public Universities. FS 08-02

    Science.gov (United States)

    California Postsecondary Education Commission, 2008

    2008-01-01

    Fees for graduate students at California's public colleges and universities have risen over the last several years, but are still lower than fees at comparable universities in other states. Fees for full-time graduate students at the California State University were $4,163 in 2007-08. This amount consists of $3,414 in systemwide fees plus…

  18. Community College League of California Trustee Handbook 2009

    Science.gov (United States)

    Smith, Cindra J.

    2009-01-01

    This handbook contains eight sections and thirty-four short chapters on topics related to being a member of a California community college governing board. The eight sections are: (1) California Community Colleges; (2) The Governing Board; (3) Toward An Effective Board; (4) Policy, Planning and Monitoring; (5) The Board and the CEO; (6)…

  19. Community College League of California Trustee Handbook 2008

    Science.gov (United States)

    Smith, Cindra J.

    2008-01-01

    This handbook contains eight sections and thirty-five short chapters on topics related to being a member of a California community college governing board. The eight sections are: (1) California Community Colleges; (2) The Governing Board; (3) Toward An Effective Board; (4) Policy, Planning and Monitoring; (5) The Board and the CEO; (6)…

  20. Are California's Schools Ready for Online Testing and Learning?

    Science.gov (United States)

    Gao, Niu

    2015-01-01

    In addition to the Common Core State Standards (CCSS), California is implementing a new, online assessment system: the California Assessment of Student Performance and Progress (CAASPP). Field tests were conducted last spring and the system is being rolled out this year, amid concerns about whether schools are technologically prepared. Using…

  1. New cooperative seismograph networks established in southern California

    Science.gov (United States)

    Hill, D.P.

    1974-01-01

    Southern California has more active faults located close to large, urban population centers than any other region in the United States. Reduction of risk to life and property posed by potential earthquakes along these active faults is a primary motivation for a cooperative earthquake research program between the U.S Geological Survey and major universities in Southern California

  2. The Tenebrionidae of California: A Time Sensitive Snapshot Assessment

    Directory of Open Access Journals (Sweden)

    Rolf Aalbu

    2014-06-01

    Full Text Available Due to a diversity of habitats and its geologic history, the US state of California hosts a spectacular assemblage of darkling beetle species (Coleoptera: Tenebrionidae. In addition to being part of the California Floristic Province, one of 34 global biodiversity hotspots identified by Conservation International, California also has additional areas which are parts of the Great Basin, Mojave, and Sonoran deserts. California is divided into nine floristic regions. Each region is assessed in terms of faunal composition and endemism. A “snapshot” of our present knowledge of the Tenebrionidae indicates that 447 currently recognized species, representing 108 genera, occur in California of which one hundred and ninety are endemic. California is compared to other nearby regions in diversity and endemism. An analysis of currently valid species vs a more realistic species account based on unpublished records of likely synonyms and known species yet to be described in the scientific literature is presented. The California Floristic Region, rather than other more arid parts of California, has the highest number of total and endemic species. Because of their high diversity and endemism, tenebrionids could potentially provide a valuable tool for monitoring the environment for conservation purposes.

  3. A Preliminary Analysis of California's New Local Control Funding Formula

    Science.gov (United States)

    Wolf, Rebecca; Sands, Janelle

    2016-01-01

    California recently overhauled its K-12 public education finance system. Enacted in 2013, the Local Control Funding Formula (LCFF) replaced California's 40-year-old funding formula. The LCFF increases district officials' fiscal flexibility; provides more resources to districts serving larger proportions of low-income, English learner (EL), and…

  4. California Dreaming - Sustaining American Lifestyle and the Car

    DEFF Research Database (Denmark)

    Jørgensen, Ulrik

    2001-01-01

    California has for several years supported new innovation in zero-emission and low emission cars and set measures for the reduction of emissions in the state for the coming years.......California has for several years supported new innovation in zero-emission and low emission cars and set measures for the reduction of emissions in the state for the coming years....

  5. Testing Incapacitation Theory: Youth Crime and Incarceration in California

    Science.gov (United States)

    Stahlkopf, Christina; Males, Mike; Macallair, Daniel

    2010-01-01

    Under incapacitation theory, higher incarceration rates are expected to correlate with accelerated reductions in crime. California's contemporary incarceration patterns offer an opportunity to analyze the validity of this theory, particularly as it applies to young people. This study focuses on California's juvenile incarceration and crime trends…

  6. 77 FR 66910 - Environmental Impact Statement, San Diego County, California

    Science.gov (United States)

    2012-11-07

    ... San Diego County, California (Federal Register Vol. 72, No 10; FR Doc E7-491) will be withdrawn. FOR... Highway Administration--California Division, 401 B Street, Suite 800, San Diego, CA 92101, Regular Office.... April, Deputy District Director--Environmental, Caltrans District 11, 4050 Taylor Street, MS 242,...

  7. Seizing the Moment for Transformation: California's Local Control Funding Formula

    Science.gov (United States)

    Miles, Karen Hawley; Feinberg, Randi

    2014-01-01

    In 2013 California adopted a new funding formula that includes a significant reinvestment in public education after years of budget cuts. The new law allocates funds differently, directing more resources to students with higher needs and providing more local control and greater transparency. This revolutionary change presents California districts…

  8. AB 1725 Model Accountability System. California Community Colleges. Revised.

    Science.gov (United States)

    California Community Colleges, Sacramento. Board of Governors.

    This report proposes a model accountability system for the California community colleges to comply with the directives of Assembly Bill 1725 (AB 1725). The purpose of the accountability system is to provide colleges and districts, the board of governors, and the California legislature with information that will allow for the continued improvement…

  9. An Economic Analysis of the California Art Royalty Statute.

    Science.gov (United States)

    Bolch, Ben W.; And Others

    1978-01-01

    The probable economic impact on the art market, museums, and the artist of California's "droit de suite" legislation, designed to yield to artists a portion of the resale value of their works, is examined. It is argued that only a few living artists will benefit. The statute, California Civil Code 986, is appended. (JMD)

  10. Proceedings of the Binational Conference on Libraries in California and Baja California (1st, Tijuana, Baja California, Mexico, January 13-14, 1984) = Memorias de la Primera Conferencia Binacional de Bibliotecas de las Californias.

    Science.gov (United States)

    Ayala, Marta Stiefel, Ed.; And Others

    This document includes the text of presentations given at the First Binational Conference on Libraries in California and Baja California, as well as minutes from four roundtables held at the conference. Following a prologue and a brief background on the conference, the following presentations are included: (1) "State Support for Public Libraries…

  11. California Report Card 2004. Focus on Children in Immigrant Families

    Science.gov (United States)

    Grossman-Swenson, Sarah; Dominguez-Arms, Amy

    2004-01-01

    This document focuses on children in immigrant families to help Californians better understand the lives of almost half of California's children and families, about whom stereotypes often prevail. The report's data--obtained from sources such as the 2000 Census, the 2001 California Health Interview Survey and the 1999 and 2002 National Survey of…

  12. Elevated Plus Maze for Mice

    OpenAIRE

    Komada, Munekazu; Takao, Keizo; Miyakawa, Tsuyoshi

    2008-01-01

    Although the mouse genome is now completely sequenced, the functions of most of the genes expressed in the brain are not known. The influence of a given gene on a specific behavior can be determined by behavioral analysis of mutant mice. If a target gene is expressed in the brain, behavioral phenotype of the mutant mice could elucidate the genetic mechanism of normal behaviors. The elevated plus maze test is one of the most widely used tests for measuring anxiety-like behavior. The test is ba...

  13. Trends in California's Water Footprint, 1992-2012

    Science.gov (United States)

    Cooley, H.; Fulton, J.

    2015-12-01

    Water and other natural resource uses are increasingly affected by globalized trade and consumption patterns. We examine how California's water footprint has changed over two decades (1992 to 2012). Four findings emerge: first, California's water footprint (WF) has grown faster than population, indicating an increased per-capita WF; second, while California's WF is primarily associated with food products, energy products are becoming more important; third, the state's internal water resources are increasingly used for products consumed outside of the state; and fourth, external water resources have provided for all of California's expanded WF and are predominately "green water," or non-managed water sources. In light of climate change and mounting pressures on water resources, California policymaking must examine these trends in order to mitigate water-related risk.

  14. California current system - Predators and the preyscape

    Science.gov (United States)

    Ainley, David G.; Adams, Peter B.; Jahncke, Jaime

    2015-06-01

    The preyscape of the California Current System (CCS), one of the most productive marine areas on Earth (Glantz and Thompson, 1981), is highly variable, as evidenced by the papers in this issue, and as such presents a challenge to Ecosystem-based fishery management (EBFM), which attempts to integrate ecosystem considerations as part of fishery management and conservation decisions. Approaches to EBFM for the waters off Washington, Oregon, and California, the CCS, have been initiated (PFMC, 2007, 2013), and are continually being developed. To inform this process, a workshop was held in September 2013 to: i) gather together the existing information on forage fish and predator dynamics in the CCS; ii) consider temporal (seasonal, annual, decadal) and spatial availability of prey complexes and why these patterns of availability occur and change; iii) summarize and present that information for discussion to a large range of experts in oceanography, fish and fisheries management, seabirds, marine mammals, and ecosystem management; and, iv) synthesize this information to be useable by fishery agencies. The papers in this special Journal of Marine Systems issue address these four points. While the full results and recommendations can be found here - "http://www.pointblue.org/uploads/assets/calcurrent/REPORT_Forage_Fish_Workshop_FINAL.pdf"

  15. Surgical malpractice in California: res judicata.

    Science.gov (United States)

    Barthel, Erik R; Stabile, Bruce E; Plurad, David; Kim, Dennis; Neville, Angela; Bricker, Scott; Putnam, Brant; Bongard, Fred

    2014-10-01

    Medical negligence claims are of increasing concern to surgeons. Although noneconomic damage awards in California are limited by the Medical Injury Compensation Reform Act (MICRA) law to $250,000, the total amount of such settlements can increase significantly based on claims for economic damages. We reviewed negligence litigation involving California surgeons to determine outcomes and monetary awards through retrospective review of surgical malpractice cases published in a legal journal. This review was limited to actions involving general surgeons. Such litigation was voluntarily reported by either defense's or plaintiff's counsel at the conclusion of the litigation. Data reviewed included alleged damages incurred by the plaintiff; plaintiff's pretrial settlement demand, plaintiff or defense verdict, use of alternate means of resolution such as arbitration or mediation, and total monetary award to the plaintiff. A total of 69 cases were reported over a 20-month period: 32 (46%) were plaintiffs' verdicts, whereas 37 (54%) were in favor of the surgeon. Only 10 (31%) of the plaintiff verdicts were by jury trial, whereas the rest were settled by pretrial agreement, mediation, or arbitration. Of cases settled by alternate dispute resolution, the median settlement was $820,000 (n = 22) compared with a median jury trial award of $300,000 (n = 10). PMID:25264649

  16. Wind resource assessment: San Nicolas Island, California

    Energy Technology Data Exchange (ETDEWEB)

    McKenna, E. [National Renewable Energy Lab., Golden, CO (United States); Olsen, T.L. [Timothy L. Olsen Consulting, (United States)

    1996-01-01

    San Nicolas Island (SNI) is the site of the Navy Range Instrumentation Test Site which relies on an isolated diesel-powered grid for its energy needs. The island is located in the Pacific Ocean 85 miles southwest of Los Angeles, California and 65 miles south of the Naval Air Weapons Station (NAWS), Point Mugu, California. SNI is situated on the continental shelf at latitude N33{degree}14` and longitude W119{degree}27`. It is approximately 9 miles long and 3.6 miles wide and encompasses an area of 13,370 acres of land owned by the Navy in fee title. Winds on San Nicolas are prevailingly northwest and are strong most of the year. The average wind speed is 7.2 m/s (14 knots) and seasonal variation is small. The windiest months, March through July, have wind speeds averaging 8.2 m/s (16 knots). The least windy months, August through February, have wind speeds averaging 6.2 m/s (12 knots).

  17. A nitrogen mass balance for California

    Science.gov (United States)

    Liptzin, D.; Dahlgren, R. A.

    2010-12-01

    Human activities have greatly altered the global nitrogen cycle and these changes are apparent in water quality, air quality, ecosystem and human health. However, the relative magnitude of the sources of new reactive nitrogen and the fate of this nitrogen is not well established. Further, the biogeochemical aspects of the nitrogen cycle are often studied in isolation from the economic and social implications of all the transformations of nitrogen. The California Nitrogen Assessment is an interdisciplinary project whose aim is evaluating the current state of nitrogen science, practice, and policy in the state of California. Because of the close proximity of large population centers, highly productive and diverse agricultural lands and significant acreage of undeveloped land, California is a particularly interesting place for this analysis. One component of this assessment is developing a mass balance of nitrogen as well as identifying gaps in knowledge and quantifying uncertainty. The main inputs of new reactive nitrogen to the state are 1) synthetic nitrogen fertilizer, 2) biological nitrogen fixation, and 3) atmospheric nitrogen deposition. Permanent losses of nitrogen include 1) gaseous losses (N2, N2O, NHx, NOy), 2) riverine discharge, 3) wastewater discharge to the ocean, and 4) net groundwater recharge. A final term is the balance of food, feed, and fiber to support the human and animal populations. The largest input of new reactive nitrogen to California is nitrogen fertilizer, but both nitrogen fixation and atmospheric deposition contribute significantly. Non-fertilizer uses, such as the production of nylon and polyurethane, constitutes about 5% of the synthetic N synthesized production. The total nitrogen fixation in California is roughly equivalent on the 400,000 ha of alfalfa and the approximately 40 million ha of natural lands. In addition, even with highly productive agricultural lands, the large population of livestock, in particular dairy cows

  18. The Story of California. Student Workbook. Teacher's Edition = Libro de Trabajo de La Historia de California. Edicion del Maestro.

    Science.gov (United States)

    Gray (Naomi) Associates, Inc., San Francisco, CA.

    The workbook is designed to accompany a textbook, "The Story of California," a Spanish-English bilingual history and geography of the state intended for classroom use by limited-English-proficient, native Spanish-speaking students in California's urban middle schools. The teacher's edition, presented here, consists of reproductions of 51 separate…

  19. Cassava is not a goitrogen in mice

    International Nuclear Information System (INIS)

    To examine the effect of cassava on the thyroid function of mice, the authors fed fresh cassava root to mice and compared this diet with low iodine diet and Purina. Cassava provided a low iodine intake and increased urine thiocyanate excretion and serum thiocyanate levels. Mice on cassava lost weight. The thyroid glands of mice on cassava were not enlarged, even when normalized for body weight. The 4- and 24-hr thyroid uptakes of mice on cassava were similar to those of mice on low iodine diets. Protein-bound [125I]iodine at 24 hr was high in mice on either the cassava or low iodine diets. The thyroid iodide trap (T/M) was similar in mice on cassava and low iodine diets. When thiocyanate was added in vitro to the incubation medium, T/M was reduced in all groups of mice; under these conditions, thiocyanate caused a dose-related inhibition of T/M. The serum thyroxine (T4) and triiodothyronine (T3) concentrations of mice on cassava were reduced compared with mice on Purina diet. Thyroid T4 and T3 contents of mice on cassava were relatively low compared with mice on Purina diet. Hepatic T3 content and T4 5'-monodeiodination in liver homogenates were reduced in mice on cassava compared with other groups. The data show that cassava does not cause goiter in mice. The thiocyanate formed from ingestation of cassava is insufficient to inhibit thyroid iodide transport or organification of iodide. The cassava diet leads to rapid turnover of hormonal iodine because it is a low iodine diet. It also impairs 5'-monodeiodination of T4 which may be related to nutritional deficiency. These data in mice do not support the concept that cassava per se has goitrogenic action in man

  20. Flatiron Mice and Ferroportin Disease

    OpenAIRE

    Johnson, Erin E.; Wessling-Resnick, Marianne

    2007-01-01

    Flatiron mice provide the first genetic model that fully recapitulates the iron-loading disorder ferroportin disease. Unlike the other known genetic causes of hemochromatosis, missense mutations in the ferroportin gene are autosomal dominant. These new findings show that ferroportin disease results from dominant negative effects rather than haplo-insufficiency.

  1. Surfactant protein D is proatherogenic in mice

    DEFF Research Database (Denmark)

    Sørensen, Grith Lykke; Madsen, Jens; Kejling, Karin;

    2006-01-01

    with wild-type C57BL/6N mice on an atherogenic diet. HDL cholesterol (HDL-C) was significantly elevated in Spd-/- mice. Treatment of Spd-/- mice with a recombinant fragment of human SP-D resulted in decreases of HDL-C (21%) as well as total cholesterol (26%), and LDL cholesterol (28%). Plasma TNF...

  2. Progress on Cherenkov Reconstruction in MICE

    CERN Document Server

    Kaplan, Daniel M; Rajaram, Durga; Winter, Miles; Cremaldi, Lucien; Sanders, David; Summers, Don

    2016-01-01

    Two beamline Cherenkov detectors (Ckov-a,-b) support particle identification in the MICE beamline. Electrons and high-momentum muons and pions can be identified with good efficiency. We report on the Ckov-a,-b performance in detecting pions and muons with MICE Step I data and derive an upper limit on the pion contamination in the standard MICE muon beam.

  3. Giardia lamblia infections in adult mice.

    OpenAIRE

    Byrd, L G; Conrad, J T; Nash, T E

    1994-01-01

    An adult mouse-Giardia lamblia model was developed and used to study host-parasite interactions, including antigenic variation. The H7/1 clone of isolate GS infected mice consistently and produced infections in 14 mouse strains tested. Infection patterns were mouse strain and Giardia isolate dependent. Antigenic variation occurred in immunocompetent mice but not in mice with severe combined immunodeficiency.

  4. AIRS Storm Front Approaching California (animation)

    Science.gov (United States)

    2005-01-01

    [figure removed for brevity, see original site] Click on the image for the AIRS Storm Front Approaching California Animation NASA's Atmospheric Infrared Sounder instrument is able to peel back cloud cover to reveal 3-D structure of a storm's water vapor content, information that can be used to improve weather forecast models. In this animation the initial visible cloud image series shows a front moving toward the West Coast of the United States as a low pressure area moves into the Pacific Northwest. The 'Pineapple Express,' a stream of moisture that originates in the tropics South of Hawaii and usually crosses Mexico to enter New Mexico and Texas, has shifted Westward and is also visible moving into Baja California. The area preceding the front appears to be relatively clear in the visible images. As the view shifts from the visible to the infrared wavelengths which highlight water vapor, we see both cloud areas contain heavy burdens of moisture. The area which appears clear in the visible images is seen to contain water vapor near the coastline as well. The viewpoint then rotates so that we can see the vertical cross section of the fronts. The variability of the vertical extent of water vapor and the amount is now clearly visible. The storm moving in from the Gulf of Alaska is more heavily laden with water vapor than that moving in from the Southwest. The moisture is concentrated in the lower atmosphere. The colors indicate the amount of water vapor present. Blue areas denote low water vapor content; green areas are medium water vapor content; red areas signify high water vapor content. The vertical grid for the final frame ranges from 250 millibar pressure at the top to 1000 millibar pressure at the bottom. The top is about 10 km (6.2 miles) above the surface of the Earth. The Atmospheric Infrared Sounder Experiment, with its visible, infrared, and microwave detectors, provides a three-dimensional look at Earth's weather. Working in tandem, the three instruments

  5. Projections of Climate Extremes in California

    Science.gov (United States)

    Mastrandrea, M. D.; Tebaldi, C.; Snyder, C.; Schneider, S. H.

    2008-12-01

    In the next few decades, it is likely that California must face the challenge of coping with increased impacts from extreme events such as heatwaves, wildfires, droughts, and floods. Such events can cause significant damages, and are responsible for a large fraction of near-term climate-related impacts every year. Some extreme events have already very likely changed in frequency and intensity over the past several decades, and these changes are expected to continue with relatively small changes in average conditions. We synthesize existing research to characterize current understanding of the direct impacts of extreme events across sectors, as well as the interactions between sectors as they are affected by extreme events. We also produce new projections of changes in the frequency and intensity of extreme events in the future across climate models, emissions scenarios, and downscaling methods for producing regional climate information, for each county in California. We evaluate historical and projected changes for a suite of temperature and precipitation-based climate indicators, and we conduct a return level analysis to investigate projected changes in extreme temperatures. Finally, we include an analysis of the future likelihood of events similar in magnitude to specific historical events, such as the July 2006 heat wave. Consistent with other studies, we find significant increases in the frequency and magnitude of both maximum and minimum temperature extremes in many areas, with the magnitude of change dependent on the magnitude of projected emissions and overall temperature increase. For example, in many regions of California, at least a ten-fold increase in frequency is projected for extreme temperatures currently estimated to occur once every 100 years, even under a moderate emissions scenario (SRES B1). Under a higher emissions scenario (SRES A2), these temperatures are projected to occur close to annually in most regions. Also consistent with other studies

  6. Prediabetes in California: Nearly Half of California Adults on Path to Diabetes.

    Science.gov (United States)

    Babey, Susan H; Wolstein, Joelle; Diamant, Allison L; Goldstein, Harold

    2016-03-01

    In California, more than 13 million adults (46 percent of all adults in the state) are estimated to have prediabetes or undiagnosed diabetes. An additional 2.5 million adults have diagnosed diabetes. Altogether, 15.5 million adults (55 percent of all California adults) have prediabetes or diabetes. Although rates of prediabetes increase with age, rates are also high among young adults, with one-third of those ages 18-39 having prediabetes. In addition, rates of prediabetes are disproportionately high among young adults of color, with more than one-third of Latino, Pacific Islander, American Indian, African-American, and multiracial Californians ages 18-39 estimated to have prediabetes. Policy efforts should focus on reducing the burden of prediabetes and diabetes through support for prevention and treatment. PMID:27197309

  7. Tissue heavy metal concentrations of stranded California sea lions (Zalophus californianus) in Southern California

    International Nuclear Information System (INIS)

    Concentrations of nine heavy metals (As, Cd, Cu, Fe, Hg, Pb, Mn, Mo and Zn) were determined in the hepatic and renal tissues of 80 stranded California sea lions (Zalophus californianus). Significant age-dependant increases were observed in liver and kidney concentrations of cadmium and mercury, and renal zinc concentrations. Hepatic iron concentrations were significantly higher in females than males. Animals with suspected domoic acid associated pathological findings had significantly higher concentrations of liver and kidney cadmium; and significantly higher liver mercury concentrations when compared to animals classified with infectious disease or traumatic mortality. Significantly higher hepatic burdens of molybdenum and zinc were found in animals that died from infectious diseases. This is the largest study of tissue heavy metal concentrations in California sea lions to date. These data demonstrate how passive monitoring of stranded animals can provide insight into environmental impacts on marine mammals. - Tissue heavy metal concentrations are valuable in population and environmental monitoring

  8. BRIEF OF AMICI CURIAE (for the California Supreme Court's Review of California's Marriage Exclusion Laws)

    OpenAIRE

    Badgett, M. V. Lee; Gates, Gary

    2007-01-01

    As scholars of sexual orientation law and public policy, amici Badgett and Gates have a substantial interest in the issue before this Court, the constitutionality of California’s exclusion of same-sex couples from 1 marriage. Amici have conducted extensive research and authored numerous studies regarding the geographic, demographic and economic characteristics of same-sex couples in California and the United States. Amici believe that the expertise and perspective that they offer as independe...

  9. From California dreaming to California data: Challenging historic models for landfill CH4 emissions

    Directory of Open Access Journals (Sweden)

    Kurt Spokas

    2015-06-01

    Full Text Available Abstract Improved quantification of diverse CH4 sources at the urban scale is needed to guide local GHG mitigation strategies in the Anthropocene. Herein, we focus on landfill CH4 emissions in California, challenging the current IPCC methodology which focuses on a climate dependency for landfill CH4 generation (methanogenesis, but does not explicitly consider climate or soil dependencies for emissions. Relying on a comprehensive California landfill database, a field-validated process-based model for landfill CH4 emissions (CALMIM, and select field measurements at 10 California sites with a variety of methods, we support the contrary position: Limited climate dependency for methanogenesis, but strong climate dependency for landfill CH4 emissions. Contrary to the historic IPCC empirical model for methanogenesis with kinetic constants related to climate, we demonstrate a simpler and more robust linear empirical relationship (r2 = 0.85; n=128 between waste mass and landfill biogas recovery [126 × 10-6 Nm3 CH4 hr-1 Mgwaste-1]. More interestingly, there are no statistically significant relationships with climate, site age, or status (open/closed for landfill biogas recovery. The current IPCC methodology does not consider soil or climate drivers for gaseous transport or seasonal methanotrophy in different cover soils. On the other hand, we illustrate strong climate and soil dependencies for landfill emissions—e.g., average intermediate cover emissions below 20 g CH4 m-2 d-1 when the site’s mean annual precipitation is >500 mm y-1. Thereby, for the California landfill CH4 inventory, the highest-emitting sites shift from landfills containing the largest mass of waste to sites dominated by intermediate cover types having a reduced rate of soil CH4 oxidation during the annual cycle. These differences have profound implications for developing more realistic, science-based urban and regional scale GHG inventories for landfill CH4 while reducing

  10. The Southern California Twin Register at the University of Southern California

    OpenAIRE

    Baker, Laura A.; Barton, Mafalda; Raine, Adrian

    2002-01-01

    The Southern California Twin Register is the result of an effort to recruit twins of all ages in the city of Los Angeles and surrounding areas. The register currently includes an ethnically diverse sample of more than 2600 twin pairs. The most recently recruited pairs have been drawn primarily from computerized records of enrollments in local public school districts, and are comparable in sex and ethnic distributions to the general public school population. An ongoing twin study of social and...

  11. The California Salmon Fly as a Food Source in Northeastern California

    OpenAIRE

    Sutton, Mark Q

    1985-01-01

    The importance and extent of aboriginal use of insect resources in California is poorly understood. Specific data on insect utilization are uncommon in the anthropological literature, although several genera have been discussed in some detail (cf. Fenenga and Fisher 1978; Swezey 1978; Fowler and Walter 1985). The purpose of this paper is to discuss one such possible insect resource, Pteronarcys californica Newport (Plecoptera: Pteronarcidae), first noted by Aldrich (1912). This species of st...

  12. Sandia National Laboratories, California: site environmental report for 1997

    International Nuclear Information System (INIS)

    Sandia National Laboratories (SNL) is committed to conducting its operations in an environmentally safe and sound manner. It is mandatory that activities at SNL/California comply with all applicable environmental statutes, regulations, and standards. Moreover, SNL/California continuously strives to reduce risks to employees, the public, and the environment to the lowest levels reasonably possible. To help verify effective protection of public safety and preservation of the environment, SNL/California maintains an extensive, ongoing environmental monitoring program. This program monitors all significant effluents and the environment at the SNL/California site perimeter. Lawrence Livermore National Laboratory (LLNL) performs off-site external radiation monitoring for both sites. These monitoring efforts ensure that emission controls are effective in preventing contamination of the environment. As part of SNL/California's Environmental Monitoring Program, an environmental surveillance system measures the possible presence of hazardous materials in groundwater, stormwater, and sewage. The program also includes an extensive environmental dosimetry program, which measures external radiation levels around the Livermore site and nearby vicinity. The Site Environmental Report describes the results of SNL/California's environmental protection activities during the calendar year. It also summarizes environmental monitoring data and highlights major environmental programs. Overall, it evaluates SNL/California's environmental management performance and documents the site's regulatory compliance status

  13. Sandia National Laboratories/California site environmental report for 1997

    Energy Technology Data Exchange (ETDEWEB)

    Condouris, R.A. [ed.] [Sandia National Labs., Livermore, CA (United States); Holland, R.C. [Science Applications International Corp. (United States)

    1998-06-01

    Sandia National Laboratories (SNL) is committed to conducting its operations in an environmentally safe and sound manner. It is mandatory that activities at SNL/California comply with all applicable environmental statutes, regulations, and standards. Moreover, SNL/California continuously strives to reduce risks to employees, the public, and the environment to the lowest levels reasonably possible. To help verify effective protection of public safety and preservation of the environment, SNL/California maintains an extensive, ongoing environmental monitoring program. This program monitors all significant effluents and the environment at the SNL/California site perimeter. Lawrence Livermore National Laboratory (LLNL) performs off-site external radiation monitoring for both sites. These monitoring efforts ensure that emission controls are effective in preventing contamination of the environment. As part of SNL/California`s Environmental Monitoring Program, an environmental surveillance system measures the possible presence of hazardous materials in groundwater, stormwater, and sewage. The program also includes an extensive environmental dosimetry program, which measures external radiation levels around the Livermore site and nearby vicinity. The Site Environmental Report describes the results of SNL/California`s environmental protection activities during the calendar year. It also summarizes environmental monitoring data and highlights major environmental programs. Overall, it evaluates SNL/California`s environmental management performance and documents the site`s regulatory compliance status.

  14. Seasonality of the transitional region of the California Current System off Baja California

    Science.gov (United States)

    Durazo, Reginaldo

    2015-02-01

    Hydrographic data collected over the period 1997-2013 are analyzed to investigate the seasonality of hydrographic features and associated geostrophic flows off the Baja California peninsula. The upper ocean in the region was found to be homogeneous in winter and spring but subdivided into two regions in the summer and autumn. In the first case, the system typically shows relatively low-temperature and salinity waters, which give it a subarctic character. In the second, only the region north of Punta Eugenia (28°N) maintains subarctic characteristics, while the southern region receives an inflow of tropical and subtropical waters that results from the weakening of northwesterly winds, which allows the poleward advection of surface waters. Also during this period, a positive wind stress curl promotes the zonal advection of North Pacific's eastern edge waters into the coast and to the north as a surface coastal flow. Average seasonal patterns of geostrophic flow at 200 dbar revealed that the differentiation into provinces is also evident at that depth, with two clearly defined cyclonic structures in summer and autumn, both separated at the latitude of Punta Eugenia. The analyses conducted also showed a clear continuity of the California undercurrent along the shelf break, with more diffuse currents in the winter. Poleward flows were observed throughout the water column, especially in summer and autumn, although the origin of the surface flow does not necessarily involve a surfacing of the California Undercurrent.

  15. U.S. Hydropower Resource Assessment - California

    Energy Technology Data Exchange (ETDEWEB)

    A. M. Conner; B. N. Rinehart; J. E. Francfort

    1998-10-01

    The U.S. Department of Energy is developing an estimate of the underdeveloped hydropower potential in the United States. For this purpose, the Idaho National Engineering and Environmental Laboratory developed a computer model called Hydropower Evaluation Software (HES). HES measures the undeveloped hydropower resources available in the United States, using uniform criteria for measurement. The software was developed and tested using hydropower information and data provided by the Southwestern Power Administration. It is a menu-driven program that allows the personal computer user to assign environmental attributes to potential hydropower sites, calculate development suitability factors for each site based on the environmental attributes present, and generate reports based on these suitability factors. This report describes the resource assessment results for the State of California.

  16. Occupational transmission of Neisseria meningitidis --- California, 2009.

    Science.gov (United States)

    2010-11-19

    Neisseria meningitidis is a leading cause of bacterial meningitis and sepsis . The case-fatality rate for meningococcal disease is 10%--14%; survivors can experience brain damage, hearing loss, limb loss, and learning disabilities . On December 11, 2009, the California Department of Public Health (CDPH) initiated an investigation of two secondary cases of meningococcal disease in a police officer and a respiratory therapist following occupational contact with an unconscious adult. This report describes the events surrounding occupational transmission of N. meningitidis and recommends measures to control and prevent secondary transmission of N. meningitidis. Breaches in infection control, notification delays, and lack of worker exposure assessment and postexposure chemoprophylaxis (PEP) likely contributed to secondary cases. Employers should provide adequate infection-control training to staff members, PEP to exposed workers, and report notifiable diseases promptly. PMID:21085089

  17. Market dynamics of biomass fuel in California

    International Nuclear Information System (INIS)

    The California market for biomass fuel purchased by independent power producers has grown substantially since 1980. The PURPA legislation that based power purchase rates upon the 'avoided cost' of public utilities resulted in construction of nearly 900 Megawatts of capacity coming online by 1991. Until 1987, most powerplants were co-sited at sawmills and burned sawmill residue. By 1990 the installed capacity of stand-alone powerplants exceeded the capacity co-sited at wood products industry facilities. The 1991 demand for biomass fuel is estimated as 6,400,000 BDT. The 1991 market value of most biomass fuel delivered to powerplants is from $34 to $47 per BDT. Biomass fuel is now obtained from forest chips, agriculture residue and urban wood waste. The proportion of biomass fuel from the wood products industry is expected to decline and non-traditional fuels are expected to increase in availability

  18. Schlumberger soundings near Medicine Lake, California

    Science.gov (United States)

    Zohdy, A.A.R.; Bisdorf, R.J.

    1990-01-01

    The use of direct current resistivity soundings to explore the geothermal potential of the Medicine Lake area in northern California proved to be challenging because of high contact resistances and winding roads. Deep Schlumberger soundings were made by expanding current electrode spacings along the winding roads. Corrected sounding data were interpreted using an automatic interpretation method. Forty-two maps of interpreted resistivity were calculated for depths extending from 20 to 1000 m. Computer animation of these 42 maps revealed that: 1) certain subtle anomalies migrate laterallly with depth and can be traced to their origin, 2) an extensive volume of low-resistivity material underlies the survey area, and 3) the three areas (east of Bullseye Lake, southwest of Glass Mountain, and northwest of Medicine Lake) may be favorable geothermal targets. Six interpreted resistivity maps and three cross-sections illustrate the above findings. -from Authors

  19. Learning in Baja California micro-enterprises

    Directory of Open Access Journals (Sweden)

    Michelle Texis Flores

    2011-01-01

    Full Text Available Mexico’s business structure has been characterized by the presence of microenterprises, particularly those averaging two workers, representing 65% of establishments in 2008 and 18% of employment. This makes them important for equity and welfare improvement of their members. This paper analyzes the performance of a group of 227 microenterprises in the state of Baja California, by the use of a practical application of the concept of learning curve arranged to incorporate returns to scale. The results indicate that in 48% of cases there is evidence of learning processes and 58% exhibited increasing returns to scale. This allows evaluating the development potential of these microenterprises and the design and implementation of proactive programs that encourage their learning and consolidation in the market.

  20. Trends in heavy oil production and refining in California

    International Nuclear Information System (INIS)

    This report is one of a series of publications assessing the feasibility of increasing domestic heavy oil production and is part of a study being conducted for the US Department of Energy. This report summarizes trends in oil production and refining in Canada. Heavy oil (10 degrees to 20 degrees API gravity) production in California has increased from 20% of the state's total oil production in the early 1940s to 70% in the late 1980s. In each of the three principal petroleum producing districts (Los Angeles Basin, Coastal Basin, and San Joaquin Valley) oil production has peaked then declined at different times throughout the past 30 years. Thermal production of heavy oil has contributed to making California the largest producer of oil by enhanced oil recovery processes in spite of low oil prices for heavy oil and stringent environmental regulation. Opening of Naval Petroleum Reserve No. 1, Elk Hills (CA) field in 1976, brought about a major new source of light oil at a time when light oil production had greatly declined. Although California is a major petroleum-consuming state, in 1989 the state used 13.3 billion gallons of gasoline or 11.5% of US demand but it contributed substantially to the Nation's energy production and refining capability. California is the recipient and refines most of Alaska's 1.7 million barrel per day oil production. With California production, Alaskan oil, and imports brought into California for refining, California has an excess of oil and refined products and is a net exporter to other states. The local surplus of oil inhibits exploitation of California heavy oil resources even though the heavy oil resources exist. Transportation, refining, and competition in the market limit full development of California heavy oil resources

  1. Identifying Phytoplankton Classes In California Reservoirs Using HPLC Pigment Analysis

    Science.gov (United States)

    Siddiqui, S.; Peacock, M. B.; Kudela, R. M.; Negrey, K.

    2014-12-01

    Few bodies of water are routinely monitored for phytoplankton composition due to monetary and time constraints, especially the less accessible bodies of water in central and southern California. These lakes and estuaries are important for economic reasons such as tourism and fishing. This project investigated the composition of phytoplankton present using pigment analysis to identify dominant phytoplankton groups. A total of 28 different sites with a wide range of salinity (0 - 60) in central and southern California were examined. These included 13 different bodies of water in central California: 6 in the Sierras, 7 in the San Francisco Bay Estuary, and 15 from southern California. The samples were analyzed using high-performance liquid-chromatography (HPLC) to quantify the pigments present (using retention time and the spectral thumbprint). Diagnostic pigments were used to indicate the phytoplankton class composition, focusing on diatoms, dinoflagellates, cryptophytes, and cyanobacteria - all key phytoplankton groups indicative of the health of the sampled reservoir. Our results indicated that cyanobacteria dominated four of the seven bodies of central California water (Mono Lake, Bridgeport Reservoir, Steamboat Slough, and Pinto Lake); cryptophytes and nannoflagellates dominated two of the central California bodies of water (Mare Island Strait and Topaz Lake); and diatoms and dinoflagellates dominated one central California body of water, Oakland Inner Harbor, comprising more than 70% of the phytoplankton present. We expect the bodies of water from Southern California to be as disparate. Though this data is only a snapshot, it has significant implications in comparing different ecosystems across California, and it has the potential to provide valuable insight into the composition of phytoplankton communities.

  2. California wind energy development: environmental support -and opposition

    International Nuclear Information System (INIS)

    Quantitative and qualitative research was conducted during 1988 and 1989 with regard to California's large wind energy developments. Environmental support and opposition were studied. Environmental concerns, especially those of local environmentalists and activists within the host communities, are limiting wind energy well below its potential in California. ''Visual Intrusion'' is by far the most salient environmental concern. Tradeoffs between scenic preservation and windpower's reliable, economical, pollution-free electricity production need to be realistically addressed. This can not occur until perceptions regarding windpower catch up with its technology. An understanding of the California experience may prove beneficial to those who are currently engaged in wind energy programs. (author)

  3. From mice to men: lessons from mutant ataxic mice

    OpenAIRE

    Cendelin, Jan

    2014-01-01

    Ataxic mutant mice can be used to represent models of cerebellar degenerative disorders. They serve for investigation of cerebellar function, pathogenesis of degenerative processes as well as of therapeutic approaches. Lurcher, Hot-foot, Purkinje cell degeneration, Nervous, Staggerer, Weaver, Reeler, and Scrambler mouse models and mouse models of SCA1, SCA2, SCA3, SCA6, SCA7, SCA23, DRPLA, Niemann-Pick disease and Friedreich ataxia are reviewed with special regard to cerebellar pathology, pat...

  4. California State Waters Map Series: offshore of Half Moon Bay, California

    Science.gov (United States)

    Cochrane, Guy R.; Dartnell, Peter; Greene, H. Gary; Johnson, Samuel Y.; Golden, Nadine E.; Hartwell, Stephen R.; Dieter, Bryan E.; Manson, Michael W.; Sliter, Ray W.; Ross, Stephanie L.; Watt, Janet T.; Endris, Charles A.; Kvitek, Rikk G.; Phillips, Eleyne L.; Erdey, Mercedes D.; Chin, John L.; Bretz, Carrie K.

    2014-01-01

    In 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of high-resolution bathymetry, marine benthic habitats, and geology within the 3-nautical-mile limit of California’s State Waters. The CSMP approach is to create highly detailed seafloor maps through collection, integration, interpretation, and visualization of swath sonar data, acoustic backscatter, seafloor video, seafloor photography, high-resolution seismic-reflection profiles, and bottom-sediment sampling data. The map products display seafloor morphology and character, identify potential marine benthic habitats, and illustrate both the surficial seafloor geology and shallow (to about 100 m) subsurface geology. The Offshore of Half Moon Bay map area is located in northern California, on the Pacific coast of the San Francisco Peninsula about 40 kilometers south of the Golden Gate. The city of Half Moon Bay, which is situated on the east side of the Half Moon Bay embayment, is the nearest significant onshore cultural center in the map area, with a population of about 11,000. The Pillar Point Harbor at the north edge of Half Moon Bay offers a protected landing for boats and provides other marine infrastructure. The map area lies offshore of the Santa Cruz Mountains, part of the northwest-trending Coast Ranges that run roughly parallel to the San Andreas Fault Zone. The Santa Cruz Mountains lie between the San Andreas Fault Zone and the San Gregorio Fault system. The flat coastal area, which is the most recent of numerous marine terraces, was formed by wave erosion about 105 thousand years ago. The higher elevation of this same terrace west of the Half Moon Bay Airport is caused by uplift on the Seal Cove Fault, a splay of the San Gregorio Fault Zone. Although originally incised into the rising terrain horizontally, the ancient terrace surface has been gently folded into a northwest-plunging syncline by

  5. Progress of MICE RFCC Module

    Energy Technology Data Exchange (ETDEWEB)

    Li, D.; Bowring, D.; DeMello, A.; Gourlay, S.; Green, M.; Li, N.; Niinikoski, T.; Pan, H.; Prestemon, S.; Virostek, S.; Zisman, M.; Bross, A.; Carcagno, R.; Kashikhin, V.; Sylvester, C.; Chen, A. B.; Guo, Bin; Li, Liyi; Xu, Fengyu; Cao, Y.; Sun, S.; Wang, Li; Yin, Lixin; Luo, Tianhuan; Summers, Don; Smith, B.; Radovinsky, A.; Zhukovsky, A.; Kaplan, D.

    2012-05-20

    Recent progress on the design and fabrication of the RFCC (RF and superconducting Coupling Coil) module for the international MICE (Muon Ionization Cooling Experiment) are reported. The MICE ionization cooling channel has two RFCC modules, each having four 201- MHz normal conducting RF cavities surrounded by one superconducting coupling coil (solenoid) magnet. The magnet is designed to be cooled by three cryocoolers. Fabrication of the RF cavities is complete; preparation for the cavity electro-polishing, low power RF measurements, and tuning are in progress at Lawrence Berkeley National Laboratory (LBNL). Fabrication of the cold mass of the first coupling coil magnet has been completed in China and the cold mass arrived at LBNL in late 2011. Preparations for testing the cold mass are currently under way at Fermilab. Plans for the RFCC module assembly and integration are being developed and are described.

  6. MAUS: MICE Analysis User Software

    CERN Document Server

    CERN. Geneva

    2012-01-01

    The Muon Ionization Cooling Experiment (MICE) has developed the MICE Analysis User Software (MAUS) to simulate and analyse experimental data. It serves as the primary codebase for the experiment, providing for online data quality checks and offline batch simulation and reconstruction. The code is structured in a Map-Reduce framework to allow parallelization whether on a personal machine or in the control room. Various software engineering practices from industry are also used to ensure correct and maintainable physics code, which include unit, functional and integration tests, continuous integration and load testing, code reviews, and distributed version control systems. Lastly, there are various small design decisions like using JSON as the data structure, using SWIG to allow developers to write components in either Python or C++, or using the SCons python-based build system that may be of interest to other experiments.

  7. Clostridium difficile in gnotobiotic mice.

    OpenAIRE

    Onderdonk, A B; Cisneros, R L; Bartlett, J. G.

    1980-01-01

    Germfree mice associated with Clostridium difficile developed intestinal disease characterized by polymorphonuclear cell infiltration of the lamina propria, diarrhea, and cecal cytotoxin concentrations positive at a 10(-6) dilution. The numbers of viable bacteria never exceeded 10(10) colony-forming units per g (dry weight). Despite the high toxin levels and chronic inflammation over a 30-day period, the mortality rate was low (less than 2%). Daily treatment of these animals with two oral dos...

  8. Linkage Disequilibrium in Wild Mice

    OpenAIRE

    Laurie, Cathy C.; Nickerson, Deborah A.; Anderson, Amy D; Weir, Bruce S.; Livingston, Robert J; Dean, Matthew D.; Smith, Kimberly L.; Schadt, Eric E; Nachman, Michael W.

    2007-01-01

    Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causative genes have been identified. The main difficulty is the extensive linkage disequilibrium (LD) in intercross progeny and the slow process of fine-scale mapping by traditional methods. Recently, new approaches have been introduced, such as association studi...

  9. Heterotopic Heart Transplantation in Mice

    OpenAIRE

    Liu, Fengchun; Kang, Sang Mo

    2007-01-01

    The mouse heterotopic heart transplantation has been used widely since it was introduced by Drs. Corry and Russell in 1973. It is particularly valuable for studying rejection and immune response now that newer transgenic and gene knockout mice are available, and a large number of immunologic reagents have been developed. The heart transplant model is less stringent than the skin transplant models, although technically more challenging. We have developed a modified technique and have complete...

  10. Antiretroviral Restriction Factors in Mice

    OpenAIRE

    Nair, Smita; Rein, Alan

    2014-01-01

    One of the most exciting areas in contemporary retrovirus research is the discovery of “restriction factors”. These are cellular proteins that act after virus entry to inhibit infection by or replication of retroviruses (and other viruses and intracellular pathogens). We briefly discuss here three antiretroviral restriction factors in mice: Fv1, APOBEC3, and tetherin, touching on both biological and molecular aspects of these restriction systems.

  11. Pup mortality in laboratory mice

    OpenAIRE

    Weber, Elin M

    2015-01-01

    Successful mouse breeding is a crucial part of providing animals for research. However, loss of single pups or entire litters after birth is a relatively common problem. Determining how pups die is crucial for the understanding of mortality, but the scientific literature does not provide a clear picture of pup mortality and the reason why pups die is still poorly understood. The overall aim with this thesis was to investigate the causes of pup mortality in laboratory mice, focusing on mat...

  12. Progressive Neurodegeneration in Aspartylglycosaminuria Mice

    OpenAIRE

    Gonzalez-Gomez, Ignacio; Mononen, Ilkka; Heisterkamp, Nora; Groffen, John; Kaartinen, Vesa

    1998-01-01

    Aspartylglycosaminuria (AGU) is one of the most common lysosomal storage disorders in humans. A mouse model for AGU has been recently generated through targeted disruption of the glycosylasparaginase gene, and at a young age the glycosyl asparaginase-deficient mice demonstrated many pathological changes found in human AGU patients (Kaartinen V, Mononen I, Voncken J-W, Gonzalez-Gomez I, Heisterkamp N, Groffen J: A mouse model for aspartylglycosaminuria. Nat Med 1996, 2:1375–1378). Our current ...

  13. Hepatotoxicity of ethanol in mice.

    OpenAIRE

    Goldin, R D; Wickramasinghe, S. N.

    1987-01-01

    Mice continuously exposed to ethanol vapour (for up to 19 days) developed fatty change in the liver (from 2 days onwards) and lesions resembling those of alcoholic hepatitis in man (from 5 days onwards). They also showed biochemical evidence of liver cell damage. Sera from ethanol-treated animals contained immunoglobulins that bound to the hepatocytes of ethanol-treated but not of control animals suggesting that exposure to ethanol was followed by an immunological response to a hepatocyte neo...

  14. Primordial Germ Cells in Mice

    OpenAIRE

    Saitou, Mitinori; Yamaji, Masashi

    2012-01-01

    Germ cell development creates totipotency through genetic as well as epigenetic regulation of the genome function. Primordial germ cells (PGCs) are the first germ cell population established during development and are immediate precursors for both the oocytes and spermatogonia. We here summarize recent findings regarding the mechanism of PGC development in mice. We focus on the transcriptional and signaling mechanism for PGC specification, potential pluripotency, and epigenetic reprogramming ...

  15. Compensatory eye movements in mice

    OpenAIRE

    Alphen, Adriaan

    2002-01-01

    textabstractThis thesis will address the generation of compensatory eye movements in naturally mutated or genetically modified mice. The reason for generating compensatory eye movements is solely related to the requirements for good vision. In a subject moving through its environment the projection of visual surround would slip across the retina and retinal slip of more than only a few degrees per second would cause blurring of the projected image and reduce visual acuity (Westheimer and McKe...

  16. Postconditioning in rats and mice

    OpenAIRE

    2006-01-01

    Objective . For subsequent studies on the molecular mechanisms of postconditioning, we aimed to identify a robust postconditioning protocol in rat and mouse heart. Design. Isolated rat hearts were subjected to different postconditioning protocols (study 1 and 2). The protection was compared to preconditioning. Rats (study 3) in vivo in two different laboratories were postconditioned. Isolated mouse hearts (study 4) and mice in vivo (study 5) were postconditioned. Results. Postconditioning did...

  17. Arterial Pressure Monitoring in Mice

    OpenAIRE

    Zhao, Xin; Ho, David; Gao, Shumin; Hong, Chull; Vatner, Dorothy E.; Vatner, Stephen F.

    2011-01-01

    The use of mice for the evaluation and study of cardiovascular pathophysiology is growing rapidly, primarily due to the relative ease for developing genetically engineered mouse models. Arterial pressure monitoring is central to the evaluation of the phenotypic changes associated with cardiovascular pathology and interventions in these transgenic and knockout models. There are four major techniques for measuring arterial pressure in the mouse: tail cuff system, implanted fluid filled catheter...

  18. Measuring Motor Coordination in Mice

    OpenAIRE

    Deacon, Robert M.J.

    2013-01-01

    Mice are increasingly being used in behavioral neuroscience, largely replacing rats as the behaviorist's animal of choice. Before aspects of behavior such as emotionality or cognition can be assessed, however, it is vital to determine whether the motor capabilities of e.g. a mutant or lesioned mouse allow such an assessment. Performance on a maze task requiring strength and coordination, such as the Morris water maze, might well be impaired in a mouse by motor, rather than cognitive, impairme...

  19. Crescent City, California Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Crescent City, California Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST)...

  20. Santa Barbara, California Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Santa Barbara, California Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST)...