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Sample records for cage bulk negative-index

  1. The split cube in a cage: bulk negative-index material for infrared applications

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Menzel, C.; Rockstuhl, C.;

    2009-01-01

    We propose the split cube in a cage (SCiC) design for application in producing a bulk metamaterial. Applying realistic material data for thin silver films, we observe an immediate convergence of the effective parameters obtained with a number of layers towards the bulk properties. Results are obt...

  2. Nested structures approach for bulk 3D negative index materials

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Lavrinenko, Andrei

    2009-01-01

    We propose a generic conceptual idea to obtain bulk 3D negative index metamaterials, which exhibit isotropic properties. The design is based on the nested structures approach, when one element providing magnetic response is inserted into another design with negative dielectric constant. Both...

  3. Bulk isotropic negative-index material design for infrared

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Lavrinenko, Andrei

    Responding to the strong call for isotropic bulk negative index material we propose a Split Cube in Car-cass design. It shows negative refractive index -1.5, figure-of-merit 2 and transmittivity 30% for one layer at the telecommunication wavelength 1.6 μm. Effective parameters converge fast with a...... number of layers. The effective parameters retrieval method based on the wave propagation simulation is proposed and compared with standard procedure. It is shown that standard restoration method while used for the S-parameters spectra calculations with pulse sources excitation can contain an error...

  4. Faraday cage angled-etching of nanostructures in bulk dielectrics

    OpenAIRE

    Latawiec, Pawel; Burek, Michael J.; Sohn, Young-Ik; Lončar, Marko

    2016-01-01

    For many emerging optoelectronic materials, heteroepitaxial growth techniques do not offer the same high material quality afforded by bulk, single-crystal growth. However, the need for optical, electrical, or mechanical isolation at the nanoscale level often necessitates the use of a dissimilar substrate, upon which the active device layer stands. Faraday cage angled-etching (FCAE) obviates the need for these planar, thin-film technologies by enabling in-situ device release and isolation thro...

  5. Negative Index Materials and Plasmonic Antennas Based Nanocouplers

    DEFF Research Database (Denmark)

    Andryieuski, Andrei

    This thesis describes the development, design and fabrication of the nanocoupler that is a device coupling light from conventional optical fiber to the nanosize plasmonic slot waveguide. This device can decrease the coupling region to several micrometers providing compact interface between an...... optical fiber and future optical integrated circuit. Multiple nanocoupler possibilities are analyzed. Two realizations are investigated: negative index metamaterial and plasmonic nanoantenna based. The cubic symmetric negative index metamaterial Split cube in Cage and Split cube in Carcass designs for the...... geometrical parameters of the nanoantenna couplers are found out. The best performance is shown by the battle axe nanocoupler that has an antenna figure of merit equal to 1.8 μm2 for five antenna periods. That is 90 times larger than antenna figure of merit for the waveguide without nanocoupler (0.02 μm2...

  6. Energy flow in negative index materials

    Institute of Scientific and Technical Information of China (English)

    Lorenzo Bolla; Michele Midrio; Carlo G. Someda

    2004-01-01

    From Maxwell's equations, we compute the speed and the direction of propagation of active power refractedfrom air into a negative index material. We prove, both analytically and numerically that the power mayrefract positively even if phase fronts refract negatively. Considerations on the usage of ray optics inproblems involving negative index materials are drawn.

  7. Chiral Negative-Index Metamaterials in Terahertz

    OpenAIRE

    Zhang, Shuang; Park, Yong-Shik; Li, Jensen; Lu, Xinchao; Zhang, Weili; Zhang, Xiang

    2008-01-01

    Negative index metamaterials (NIMs) give rise to unusual and intriguing properties and phenomena, which may lead to important applications such as superlens, subwavelength cavity and slow light devices. However, the negative refractive index in metamaterials normally requires a stringent condition of simultaneously negative permittivity and negative permeability. A new class of negative index metamaterials - chiral NIMs, have been recently proposed. In contrast to the conventional NIMs, chira...

  8. Chiral Negative-Index Metamaterials in Terahertz

    CERN Document Server

    Zhang, Shuang; Li, Jensen; Lu, Xinchao; Zhang, Weili; Zhang, Xiang

    2008-01-01

    Negative index metamaterials (NIMs) give rise to unusual and intriguing properties and phenomena, which may lead to important applications such as superlens, subwavelength cavity and slow light devices. However, the negative refractive index in metamaterials normally requires a stringent condition of simultaneously negative permittivity and negative permeability. A new class of negative index metamaterials - chiral NIMs, have been recently proposed. In contrast to the conventional NIMs, chiral NIMs do not require the above condition, thus presenting a very robust route toward negative refraction. Here we present the first experimental demonstration of a chiral metamaterial exhibiting negative refractive index down to n=-5 at terahertz frequencies, with only a single chiral resonance. The strong chirality present in the structure lifts the degeneracy for the two circularly polarized waves and relieves the double negativity requirement. Chiral NIM are predicted to possess intriguing electromagnetic properties t...

  9. Controlling the second-harmonic in a phase matched negative-index metamaterial

    OpenAIRE

    Rose, Alec; Huang, Da; Smith, David R.

    2011-01-01

    Nonlinear metamaterials (NLMMs) have been predicted to support new and exciting domains in the manipulation of light, including novel phase matching schemes for wave mixing. Most notable is the so-called nonlinear-optical mirror, in which a nonlinear negative-index medium emits the generated frequency towards the source of the pump. For the first time, we experimentally demonstrate the nonlinear-optical mirror effect in a bulk negative-index NLMM, along with two other novel phase matching con...

  10. Negative-Index Media for Matter Waves

    Science.gov (United States)

    Perales, F.; Bocvarski, V.; Baudon, J.; Hamamda, M.; Grucker, J.; Dutier, G.; Mainos, C.; Boustimi, M.; Ducloy, M.

    2010-02-01

    One reviews the recently introduced field of matter-wave "meta-optics", i.e. the extension of optical negative-index media (NIM) to atom optics. After emphasizing the differences with light meta-optics and particularly the necessary transient character of NIM's in atom optics, we present the way of generating matter-wave NIM's and their general properties: negative refraction, atom meta-lenses. Finally their specific features are reviewed: longitudinal wave packet narrowing associated to a time-reversal effect, transient revivals of evanescent matter waves and atom reflection echoes at a potential barrier.

  11. Towards negative index self-assembled metamaterials

    CERN Document Server

    Fruhnert, Martin; Lederer, Falk; Rockstuhl, Carsten

    2016-01-01

    We investigate the magnetic response of meta-atoms that can be fabricated by a bottom-up technique. Usually such meta-atoms consist of a dielectric core surrounded by a large number of solid metallic nanoparticles. In contrast to those meta-atoms considered thus far, we study here for the first time hollow metallic nanoparticles (shells). In doing so we solve one of the most pertinent problems of current self-assembled metamaterials, namely implementing meta-atoms with sufficiently large resonance strength and small absorption. Both conditions have to be met for deep sub-wavelength meta-atoms to obtain effectively homogeneous metamaterials which may be meaningfully described by negative material parameters. Eventually we show that by using these findings self-assembled negative index materials come in reach.

  12. Structures with negative index of refraction

    Science.gov (United States)

    Soukoulis, Costas M.; Zhou, Jiangfeng; Koschny, Thomas; Zhang, Lei; Tuttle, Gary

    2011-11-08

    The invention provides simplified negative index materials (NIMs) using wire-pair structures, 4-gap single ring split-ring resonator (SRR), fishnet structures and overleaf capacitor SRR. In the wire-pair arrangement, a pair of short parallel wires and continuous wires are used. In the 4-gap single-ring SRR, the SRRs are centered on the faces of a cubic unit cell combined with a continuous wire type resonator. Combining both elements creates a frequency band where the metamaterial is transparent with simultaneously negative .di-elect cons. and .mu.. In the fishnet structure, a metallic mesh on both sides of the dielectric spacer is used. The overleaf capacitor SRR changes the gap capacities to small plate capacitors by making the sections of the SRR ring overlap at the gaps separated by a thin dielectric film. This technique is applicable to conventional SRR gaps but it best deploys for the 4-gap single-ring structures.

  13. Nested structures approach in designing an isotropic negative-index material for infrared

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Lavrinenko, Andrei

    2009-01-01

    We propose a new generic approach for designing isotropic metamaterial with nested cubic structures. As an example, a three-dimensional isotropic unit cell design "Split Cube in Cage" (SCiC) is shown to exhibit an effective negative refractive index on infrared wavelengths. We report on the refra...... refractive index reaching -2.3 and the figure of merit as high as 2.7. The structure exhibits potential for application as a building block of isotropic negative-index materials....

  14. Subwavelength resolution with a negative-index metamaterial superlens

    Science.gov (United States)

    Aydin, Koray; Bulu, Irfan; Ozbay, Ekmel

    2007-06-01

    Negative-index metamaterials are candidates for imaging objects with sizes smaller than a half-wavelength. The authors report an impedance-matched, low loss negative-index metamaterial superlens that is capable of resolving subwavelength features of a point source with a 0.13λ resolution, which is the highest resolution achieved by a negative-index metamaterial. By separating two point sources with a distance of λ /8, they were able to detect two distinct peaks on the image plane. They also showed that the metamaterial based structure has a flat lens behavior.

  15. Numerical study of electromagnetic waves interacting with negative index materials.

    Science.gov (United States)

    Kolinko, Pavel; Smith, David

    2003-04-01

    We study numerically the electromagnetic scattering properties of structures with negative indices of refraction. To perform this analysis, we utilize a commercial finite-element based electromagnetic solver (HFSS, Ansoft), in which a negative index material can be formed from mesh elements whose permittivity and permeability are both negative. In particular, we investigate the expected transmission characteristics of a finite beam incident on negative index prisms and lenses. We also confirm numerically the predicted superlens effect of an image formed by a planar slab with index n=-1, using two subwavelength (ë/20) slits as objects. PMID:19461776

  16. Dynamics of evanescent matter waves in negative-index media

    Science.gov (United States)

    Hamamda, M.; Bocvarski, V.; Perales, F.; Baudon, J.; Dutier, G.; Mainos, C.; Boustimi, M.; Ducloy, M.

    2010-11-01

    Semi-evanescent and evanescent matter waves produced by an atom wave packet impinging on a repulsive barrier can be back-refracted and reconstructed by the application of negative-index 'comoving' potential pulses. One shows that those collapses and revivals generate a matter wave confined on both sides of the barrier border ('surface matter wave') and should be observable via the retardation of atom reflection from the barrier interface. This property, joined to the possibility recently demonstrated of inducing negative refraction of atom waves, makes such potentials a matter-wave counterpart of negative-index materials or 'meta materials' well known in light optics.

  17. Surface waves excited from negative-index materials

    International Nuclear Information System (INIS)

    Studies on electromagnetic surface waves along the surface of a finitely thick plate made from negative-index materials are presented in this paper. Through theoretical analysis we worked out requirements on permeability and permittivity for surface waves to exist. Comparing with the model of a plate with infinite thickness, the one of finite thickness shows released requirements, leading to potential applications in guiding wave and developing radiation sources. With the help of particle-in-cell simulations, we examined theoretical predictions and demonstrated field distributions of surface waves. - Highlights: • Surface modes along a finitely thick plate with/without PEC substrate are studied. • Both positive-index material and negative-index material models are investigated. • Requirements are obtained to make surface waves exist. • The requirements are released comparing with an infinitely thick model. • Higher frequency of some surface modes can be excited with thicker NIM plate

  18. Self-assembled hexagonal double fishnets as negative index materials

    CERN Document Server

    Lodewijks, Kristof; Van Roy, Willem; Borghs, Gustaaf; Van Dorpe, Pol

    2010-01-01

    We show experimentally the successful use of colloidal lithography for the fabrication of negative index metamaterials in the near-infrared wavelength range. In particular, we investigated a specific implementation of the widely studied double fishnet metamaterials, consisting of a gold-silica-gold layer stack perforated by a hexagonal array of round holes. Tuning of the hole diameter allows us to tailor these self-assembled metamaterials both as single- ({\\epsilon} < 0) and double ({\\epsilon} < 0 and {\\mu} < 0) negative metamaterials.

  19. Defect in photonic crystal with negative index material

    Institute of Scientific and Technical Information of China (English)

    TANG Kang-song; XIANG Yuan-jiang; WEN Shuang-chun

    2006-01-01

    The transmission property of the photonic crystal containing negative index material is analyzed by means of transfer matrix method.It is demonstrated that a defect mode appears in the conventional Bragg gap and the defect mode is sensitive to the position of the defect cell.For the first time to our knowledge we introduce two defects into such a structure and discuss the dependence of the transmission on the interval of the two defect cells.It is found that a wide degenerate defect mode appears in the Bragg gap,and this degenerate defect mode splits into two different defect modes when the two defect cells become closer.

  20. Stability criterion for Gaussian pulse propagation through negative index materials

    International Nuclear Information System (INIS)

    We analyze the dynamics of propagation of a Gaussian light pulse through a medium having a negative index of refraction employing the recently reported projection operator technique. The governing modified nonlinear Schroedinger equation, obtained by taking into account the Drude dispersive model, is expressed in terms of the parameters of Gaussian pulse, called collective variables, such as width, amplitude, chirp, and phase. This approach yields a system of ordinary differential equations for the evolution of all the pulse parameters. We demonstrate the dependence of stability of the fixed-point solutions of these ordinary differential equations on the linear and nonlinear dispersion parameters. In addition, we validate the analytical approach numerically utilizing the method of split-step Fourier transform.

  1. Evidence of hollow golden cages

    OpenAIRE

    Bulusu, Satya; Li, Xi; Wang, Lai-Sheng; Zeng, Xiao Cheng

    2006-01-01

    The fullerenes are the first “free-standing” elemental hollow cages identified by spectroscopy experiments and synthesized in the bulk. Here, we report experimental and theoretical evidence of hollow cages consisting of pure metal atoms, Aun− (n = 16–18); to our knowledge, free-standing metal hollow cages have not been previously detected in the laboratory. These hollow golden cages (“bucky gold”) have an average diameter >5.5 Å, which can easily accommodate one guest atom inside.

  2. Sub-picosecond optical switching with a negative index metamaterial

    Energy Technology Data Exchange (ETDEWEB)

    Dani, Keshav M [Los Alamos National Laboratory; Upadhya, Prashant C [Los Alamos National Laboratory; Zahyum, Ku [CHTM-UNM

    2009-01-01

    Development of all-optical signal processing, eliminating the performance and cost penalties of optical-electrical-optical conversion, is important for continu,ing advances in Terabits/sec (Tb/s) communications.' Optical nonlinearities are generally weak, traditionally requiring long-path, large-area devicesl,2 or very high-Q, narrow-band resonator structures.3 Optical metamaterials offer unique capabilities for optical-optical interactions. Here we report 600 femtosecond (fs) all-optical modulation using a fIShnet (2D-perforated metallamorphous-Si (a-Si)/metal film stack) negative-index meta material with a structurally tunable broad-band response near 1.2 {micro}m. Over 20% modulation (experimentally limited) is achieved in a path length of only 116 nm by photo-excitation of carriers in the a-Si layer. This has the potential for Tb/s aU-optical communication and will lead to other novel, compact, tunable sub-picosecond (ps) photonic devices.

  3. Low-loss negative index metamaterials for X, Ku, and K microwave bands

    International Nuclear Information System (INIS)

    Low-loss, negative-index of refraction metamaterials were designed and tested for X, Ku, and K microwave frequency bands. An S-shaped, split-ring resonator was used as a unit cell to design homogeneous slabs of negative-index metamaterials. Then, the slabs of metamaterials were cut unto prisms to measure experimentally the negative index of refraction of a plane electromagnetic wave. Theoretical simulations using High-Frequency Structural Simulator, a finite element equation solver, were in good agreement with experimental measurements. The negative index of refraction was retrieved from the angle- and frequency-dependence of the transmitted intensity of the microwave beam through the metamaterial prism and compared well to simulations; in addition, near-field electromagnetic intensity mapping was conducted with an infrared camera, and there was also a good match with the simulations for expected frequency ranges for the negative index of refraction

  4. Plasmon-Enhanced Photonic Crystal Negative Index Materials for Superlensing Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Negative index materials (NIMs) offer tremendous potential for the formation of highly compact as well as large-area deployable thin-film optical components. Omega...

  5. Focus modulation of cylindrical vector beams through negative-index grating lenses

    Science.gov (United States)

    Wang, Shengming; Xu, Ji; Zhong, Yi; Ren, Rong; Lu, Yunqing; Wan, Hongdan; Wang, Jin; Ding, Jianping

    2016-08-01

    A cylindrically symmetric negative-index grating lens composed of unitary material is proposed as an effective method to modulate the focusing of cylindrical vector beams (CVBs). The grating parameters are designed to obtain an appropriate negative index, and the lens profile is tailored to realize the constructive interference. The plano-concave lens is parameterized to achieve desired focal length and the plano-cone lens is proposed to obtain large depth of focus. An optical needle is generated with radially polarized incidence, and an optical tube is achieved with incidence of azimuthal polarization. Moreover, the presented modulation methods can be applied for any arbitrary polarized CVBs. This work offers a more flexible and effective approach to design negative-index lenses for subwavelength focusing of CVBs, which has potential application value in related areas, such as optical trapping, and other nano-optics fields.

  6. Nanoengineering of a Negative-Index Binary-Staircase Lens for the Optics Regime

    CERN Document Server

    Casse, B D F; Lu, W T; Huang, Y J; Selvarasah, S; Dokmeci, M; Sridhar, S

    2008-01-01

    We show that a binary-staircase optical element can be engineered to exhibit an effective negative index of refraction, thereby expanding the range of optical properties theoretically available for future optoelectronic devices. The mechanism for achieving a negative-index lens is based on exploiting the periodicity of the surface corrugation. By designing and nanofabricating a plano-concave binary-staircase lens in the InP/InGaAsP platform, we have experimentally demonstrated at 1.55 microns that such negative-index concave lenses can focus plane waves. The beam propagation in the lens was studied experimentally and was in excellent agreement with the three-dimensional finite-difference time-domain numerical simulations.

  7. Modulation instability of structured-light beams in negative-index metamaterials

    CERN Document Server

    Silahli, Salih Z; Litchinitser, Natalia M

    2016-01-01

    One of the most fundamental properties of isotropic negative-index metamaterials, namely opposite directionality of the Poynting vector and the wavevector, enable many novel linear and nonlinear regimes of light-matter interactions. Here, we predict distinct characteristics of azimuthal modulation instability of optical vortices with different topological charges in negative-index metamaterials with Kerr-type and saturable nonlinearity. We derive an analytical expression for the spatial modulation-instability gain for the Kerr-nonlinearity case and show that a specific condition relating the diffraction and the nonlinear lengths must be fulfilled for the azimuthal modulation instability to occur. Finally, we investigate the rotation of the necklace beams due to the transfer of orbital angular momentum of the generating vortex onto the movement of solitary necklace beams. We show that the direction of rotation is opposite in the positive- and negative-index materials.

  8. Negative index of refraction, perfect lenses and transformation optics -- some words of caution

    CERN Document Server

    Bergamin, Luzi

    2010-01-01

    In this paper we show that a negative index of refraction is not a direct implication of transformation optics with orientation-reversing diffeomorphisms. Rather a negative index appears due to a specific choice of sign freedom. Furthermore, we point out that the transformation designed lens, which relies on the concept of spacetime folding, does not amplify evanescent modes, in contrast to the Pendry-Veselago lens. Instead, evanescent modes at the image point are produced by a duplicated source and thus no imaging of the near field (perfect lensing) takes place.

  9. Photonic band structure and effective medium properties of doubly-resonant core-shell metallo-dielectric nanowire arrays: low-loss, isotropic optical negative-index behavior

    International Nuclear Information System (INIS)

    We investigate theoretically and numerically the photonic band structure in the optical domain of an array of core–shell metal-semiconductor nanowires. Corresponding negative-index photonic bands are calculated, showing isotropic equifrequency surfaces. The effective (negative) electric permittivity and magnetic permeability, retrieved from S-parameters, are used to compare the performance of such nanowire arrays with homogeneous media in canonical examples, such as refraction through a prism and flat-lens focusing. Very good agreement is found, confirming the effective medium behavior of the nanowire array as a low-loss, isotropic (2D) and bulk, optical negative index metamaterial. Indeed, disorder is introduced to further stress its robustness. (paper)

  10. Specific absorption rate analysis of broadband mobile antenna with negative index metamaterial

    Science.gov (United States)

    Alam, Touhidul; Faruque, Mohammad Rashed Iqbal; Islam, Mohammad Tariqul

    2016-03-01

    This paper presents a negative index metamaterial-inspired printed mobile wireless antenna that can support most mobile applications such as GSM, UMTS, Bluetooth and WLAN frequency bands. The antenna consists of a semi-circular patch, a 50Ω microstrip feed line and metamaterial ground plane. The antenna occupies a very small space of 37 × 47 × 0.508 mm3, making it suitable for mobile wireless application. The perceptible novelty shown in this proposed antenna is that reduction of specific absorption rate using the negative index metamaterial ground plane. The proposed antenna reduced 72.11 and 75.53 % of specific absorption rate at 1.8 and 2.4 GHz, respectively.

  11. Modulation instability of structured-light beams in negative-index metamaterials

    Science.gov (United States)

    Silahli, Salih Z.; Walasik, Wiktor; Litchinitser, Natalia M.

    2016-05-01

    One of the most fundamental properties of isotropic negative-index metamaterials (NIMs), namely opposite directionality of the Poynting vector and the wavevector, enable many novel linear and nonlinear regimes of light–matter interactions. Here, we predict distinct characteristics of azimuthal modulation instability (MI) of optical vortices with different topological charges in NIMs with Kerr-type and saturable nonlinearity. We derive an analytical expression for the spatial modulation-instability gain for the Kerr-nonlinearity case and show that a specific condition relating the diffraction and the nonlinear lengths must be fulfilled for the azimuthal MI to occur. Finally, we investigate the rotation of the necklace beams due to the transfer of orbital angular momentum of the generating vortex on the movement of solitary necklace beams. We show that the direction of rotation is opposite in positive- and negative-index materials.

  12. Flat lenses constructed by graded negative index-based photonic crystals with tuned configurations

    International Nuclear Information System (INIS)

    Flat lenses are designed by means of graded negative refractive index-based photonic crystals (PCs) constructed using air-holes tuned with different shapes. By gradually modifying the filling factor along the transverse direction, we obtain the graded negative index-based lenses for the purpose of focusing an incident plane wave. The finite-difference and time-domain (FDTD) algorithm is adopted for numerical calculation. Our calculation results indicate that these lenses can finely focus incident plane waves. Moreover, for the same size of air-holes, the focusing properties of the lens with rectangular air-holes are better than those with the other shaped air-holes. The graded negative index PCs lenses could possibly enable new applications in optoelectronic systems. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  13. Creating double negative index materials using the Babinet principle with one metasurface

    OpenAIRE

    Zhang, Lei; Koschny, Thomas; Soukoulis, Costas M.

    2013-01-01

    Metamaterials are patterned metallic structures which permit access to a novel electromagnetic response, negative index of refraction, impossible to achieve with naturally occurring materials. Using the Babinet principle, the complementary split ring resonator (SRR) is etched in a metallic plate to provide negative \\epsilon, with perpendicular direction. Here we propose a new design, etched in a metallic plate to provide negative magnetic permeability \\mu, with perpendicular direction. The co...

  14. Strong effect of surfaces on resolution limit of negative-index "superlens"

    OpenAIRE

    Bratkovsky, A. M.; A. Cano; Levanyuk, A. P.

    2004-01-01

    We show that subwavelength imaging by negative index materials (NIM), related to their "soft" electromagnetic response, is very (and non trivially) sensitive to the surface properties. A minute deviation of dielectric permittivity epsilon or magnetic permeability mu from the ideal values epsilon = mu = -1 in thin surface layer(s) results in drastic reduction of the resolution limit of a NIM slab. There may be a gap in the polariton spectrum and this would allow establishment of a stationary r...

  15. Measurements of Broadband Negative Index in Space-Coiling Acoustic Metamaterials

    OpenAIRE

    Xie, Yangbo; Popa, Bogdan-Ioan; Zigoneanu, Lucian; Cummer, Steven A.

    2012-01-01

    We report the experimental demonstration of broadband negative refractive index obtained in a labyrinthine acoustic metamaterial structure. Two different approaches were employed to prove the metamaterial negative index nature: one-dimensional extractions of effective parameters from reflection and transmission measurements, and two-dimensional prism-based measurements that convincingly show the transmission angle corresponding to negative refraction. The transmission angles observed in the l...

  16. Nonlinear excitations in negative index materials: Modulational instability and solitary wave solutions

    Science.gov (United States)

    Sharma, Vivek Kumar; Goyal, Amit

    2016-05-01

    We explore the modulational instability and existence of dark, bright solitary wave solutions in negative index-materials (NIMs) modeled by generalized nonlinear Schrödinger equation with competing cubic-quintic and higher-order nonlinearities with dispersive permittivity and permeability. Parameter domains are delineated in which these ultrashort pulses exist in NIMs. Unlike the ordinary materials, these novel excitations occur for different signs of dispersion, Kerr and non-Kerr nonlinearities.

  17. Modulation instability in a triangular three-core coupler with a negative-index material channel

    Science.gov (United States)

    Shafeeque Ali, A. K.; Nithyanandan, K.; Porsezian, K.; Maimistov, Andrei I.

    2016-03-01

    A theoretical investigation of the modulation instability (MI) in the three core triangular oppositely directed coupler with negative index material channel is presented. This class of couplers have an effective feedback mechanism due to the opposite directionality of the phase velocities in the negative and positive index channels. It is found that the MI in the nonlinear three core triangular oppositely directed coupler is significantly influenced by the ratio of the forward- to backward-propagating wave power and nonlinearity. Also, in the case of the normal dispersion regime a threshold-like behavior is observed, whereas this behavior is not identified in the anomalous dispersion regime. For the asymmetric case (h\

  18. Three-dimensional negative index of refraction at optical frequencies by coupling plasmonic waveguides.

    Science.gov (United States)

    Verhagen, Ewold; de Waele, René; Kuipers, L; Polman, Albert

    2010-11-26

    We identify a route towards achieving a negative index of refraction at optical frequencies based on coupling between plasmonic waveguides that support backwards waves. We show how modal symmetry can be exploited in metal-dielectric waveguide pairs to achieve negative refraction of both phase and energy. Control of waveguide coupling yields a metamaterial consisting of a one-dimensional multilayer stack that exhibits an isotropic index of -1 at a free-space wavelength of 400 nm. The concepts developed here may inspire new low-loss metamaterial designs operating close to the metal plasma frequency. PMID:21231386

  19. Three-dimensional negative index of refraction at optical frequencies by coupling plasmonic waveguides

    CERN Document Server

    Verhagen, Ewold; L.,; Kuipers,; Polman, Albert

    2010-01-01

    We identify a route towards achieving a negative index of refraction at optical frequencies based on coupling between plasmonic waveguides that support backwards waves. We show how modal symmetry can be exploited in metal-dielectric waveguide pairs to achieve negative refraction of both phase and energy. By properly controlling coupling between adjacent waveguides, a metamaterial consisting of a one-dimensional multilayer stack exhibiting an isotropic index of -1 can be achieved at a free-space wavelength of 400 nm. The general concepts developed here may inspire new low-loss metamaterial designs operating close to the metal plasma frequency.

  20. Three-Dimensional Negative Index of Refraction at Optical Frequencies by Coupling Plasmonic Waveguides

    Science.gov (United States)

    Verhagen, Ewold; de Waele, René; Kuipers, L.; Polman, Albert

    2010-11-01

    We identify a route towards achieving a negative index of refraction at optical frequencies based on coupling between plasmonic waveguides that support backwards waves. We show how modal symmetry can be exploited in metal-dielectric waveguide pairs to achieve negative refraction of both phase and energy. Control of waveguide coupling yields a metamaterial consisting of a one-dimensional multilayer stack that exhibits an isotropic index of -1 at a free-space wavelength of 400 nm. The concepts developed here may inspire new low-loss metamaterial designs operating close to the metal plasma frequency.

  1. A single-layer wide-angle negative-index metamaterial at visible freque

    Energy Technology Data Exchange (ETDEWEB)

    Burgos, Stanley P. [California Inst. of Technology (CalTech), Pasadena, CA (United States); de Waele, Rene [FOM Inst. AMOLF, Amersterdam (Netherlands); Polman, Albert [FOM Inst. AMOLF, Amersterdam (Netherlands); Atwater, Harry A. [California Inst. of Technology (CalTech), Pasadena, CA (United States)

    2010-04-18

    Metamaterials are materials with artificial electromagnetic properties defined by their sub-wavelength structure rather than their chemical composition. Negative-index materials (NIMs) are a special class of metamaterials characterized by an effective negative index that gives rise to such unusual wave behaviour as backwards phase propagation and negative refraction. These extraordinary properties lead to many interesting functions such as sub-diffraction imaging and invisibility cloaking. So far, NIMs have been realized through layering of resonant structures, such as split-ring resonators, and have been demonstrated at microwave to infrared frequencies over a narrow range of angles-of-incidence and polarization. However, resonant-element NIM designs suffer from the limitations of not being scalable to operate at visible frequencies because of intrinsic fabrication limitations, require multiple functional layers to achieve strong scattering and have refractive indices that are highly dependent on angle of incidence and polarization. Here we report a metamaterial composed of a single layer of coupled plasmonic coaxial waveguides that exhibits an effective refractive index of -2 in the blue spectral region with a figure-of-merit larger than 8. The resulting NIM refractive index is insensitive to both polarization and angle-of-incidence over a ±50° angular range, yielding a wide-angle NIM at visible frequencies.

  2. Influence of birefringence in the instability spectra of oppositely directed coupler with negative index material channel

    Science.gov (United States)

    Shafeeque Ali, A. K.; Nithyanandan, K.; Porsezian, K.; Maimistov, Andrei I.

    2016-02-01

    A theoretical investigation on the influence of birefringence in the modulational instability (MI) spectra of an oppositely directed coupler (ODC) with a negative index material (NIM) channel is presented. We study the effect of birefringence on MI in linear and circular birefringent ODCs for both normal and anomalous dispersion regimes. It is found that besides the instability band due to nonlinear positive index material (PIM) and negative index material (NIM) channels, new symmetric instability regions are observed as a result of birefringent effects. Also defocusing nonlinearity suppresses the NIM band in the normal dispersion regime, but in the anomalous dispersion regime the defocusing nonlinearity enhances the gain of the NIM band. In contrast to the case of linear birefringence, in terms of MI gain from circular birefringence, only two birefringent bands dominate: the inherently PIM and NIM bands. This preponderance is attributed to the fact that the cross-phase modulation effect for the case of circular birefringence is stronger, thus allowing a better coupling between the beams, which results in the enhancement of the gain. Therefore, the manipulation of MI and solitons in an ODC is better performed when the birefringence is circular rather than linear. Here we report how to generate and manipulate MI and solitons in birefringent ODCs with a particular emphasis on a NIM channel.

  3. Effects of negative index medium defect layers on the trans mission properties of one-dimensional photonic crystal

    Institute of Scientific and Technical Information of China (English)

    XIANG Yuan-jiang; DAI Xiao-yu; WEN Shuang-chun

    2007-01-01

    School of Computer and Communication, Hunan University, Changsha 410082, ChinaThe photonic band gap structure of 1D photonic crystal with a negative index medium defect layer is studied by using the transfer matrix method. Investigations show that the introdution of negative index medium defect layer and the increase of the negative index value will result in an extension of the band gap. Moreover, by increasing the negative index, the width of defect layer and the numbers of period photonic crystal, the width of defect modes will be narrowed, which is advantaged to obtain optical filters with narrow band. Finally, the effects of absorption on the properties of band gap and on defect modes have been discussed.

  4. Physics of Negative Refraction and Negative Index Materials Optical and Electronic Aspects and Diversified Approaches

    CERN Document Server

    Krowne, Clifford M

    2007-01-01

    This book deals with the subject of optical and electronic negative refraction (NR) and negative index materials NIM). Diverse approaches for achieving NR and NIM are covered, such as using photonic crystals, phononic crystals, split-ring resonators (SRRs) and continuous media, focusing of waves, guided-wave behavior, and nonlinear effects. Specific topics treated are polariton theory for LHMs (left handed materials), focusing of waves, guided-wave behavior, nonlinear optical effects, magnetic LHM composites, SRR-rod realizations, low-loss guided-wave bands using SRR-rods unit cells as LHMs, NR of electromagnetic and electronic waves in uniform media, field distributions in LHM guided-wave structures, dielectric and ferroelectric NR bicrystal heterostructures, LH metamaterial photonic-crystal lenses, subwavelength focusing of LHM/NR photonic crystals, focusing of sound with NR and NIMs, and LHM quasi-crystal materials for focusing.

  5. A Three-Dimensionally Isotropic and Perfectly Vacuum-Impedance-Matched Negative-Index Material

    Science.gov (United States)

    Shen, Jian Qi

    2014-12-01

    A new scenario for realizing a gain left-handed atomic vapor medium based on both dressed-state mixed-parity transitions (for simultaneous electric- and magnetic-dipole resonance) and incoherently-pumped population transfer (for high gain amplification) in a four-level atomic system is suggested. Dressed-state assisted simultaneous electric- and magnetic-dipole allowed transitions in such a four-level atomic system (of, e.g., neutral alkali-metal atoms such as lithium and potassium atoms) are utilized for achieving negative refractive index with impedance perfectly matched to vacuum. The attractive features of the present scenario include: i) three-dimensionally isotropic negative indices; ii) incoherent-gain wave amplification; iii) perfect impedance matching to vacuum. All these important properties of the double-negative medium would have potential applications in designing some optical and photonic devices, including particularly subwavelength focusing system and negative-index superlens for perfect imaging.

  6. Minimization of losses in a structure having a negative index of refraction

    International Nuclear Information System (INIS)

    A structure consisting of an array of wires cladded with a nonmagnetic dielectric and embedded in a ferrimagnetic host has been calculated to have a negative index of refraction. The structure has moderate losses over a bandwidth of a few GHz. The calculation takes into account the skin effect within the wires and is valid provided the wavelength of electromagnetic waves in the structure is long compared to the radius of the cladded wires. The structure's electromagnetic response is accurately described by the ferrimagnet's permeability and a permittivity derived in the long wavelength limit. Losses can be minimized by choosing the pass band to be between 30 and 80% of the plasma frequency and by choosing wires to be of the highest possible conductivity and largest radius compatible with the required plasma frequency

  7. Measurement of a broadband negative index with space-coiling acoustic metamaterials.

    Science.gov (United States)

    Xie, Yangbo; Popa, Bogdan-Ioan; Zigoneanu, Lucian; Cummer, Steven A

    2013-04-26

    We report the experimental demonstration of a broadband negative refractive index obtained in a labyrinthine acoustic metamaterial structure. Two different approaches were employed to prove the metamaterial negative index nature: one-dimensional extractions of effective parameters from reflection and transmission measurements and two-dimensional prism-based measurements that convincingly show the transmission angle corresponding to negative refraction. The transmission angles observed in the latter case also agree very well with the refractive index obtained in the one-dimensional measurements and numerical simulations. We expect this labyrinthine metamaterial to become the unit cell of choice for practical acoustic metamaterial devices that require broadband and significantly negative indices of refraction. PMID:23679743

  8. Negative Index Refraction in the Complex Ginzburg—Landau Equation in Connection with the Experimental CIMA Reaction

    International Nuclear Information System (INIS)

    In comparison with the phenomenon of negative index refraction observed in artificial meta-materials, it is interesting to ask if this type of behavior also exists or not in reaction-diffusion systems that support nonlinear chemical waves. Previous studies indicate that the negative index refraction could occur on a interface between a medium of a normal wave and a medium that supports anti-waves. Here we investigate the phenomenon in the complex Ginzburg—Landau equation (CGLE) in a close relationship with the quantitative model for the chloriteiodide-malonic acid (CIMA) reaction. The amplitude equation CGLE is deduced from the CIMA reaction, and simulations with mapped parameters from the reaction-diffusion equation reveal that the competition between normal waves and anti-waves on the interface determines whether the negative index refraction occurs or not

  9. Development of Negative Index of Refraction Metamaterials with Split Ring Resonators and Wires for RF Lens Applications

    Science.gov (United States)

    Parazzoli, Claudio G.; Greegor, Robert B.; Tanielian, M. H.

    Metamaterials are engineered ring and wire composites whose response to an incident electromagnetic wave can be described by an effective negative dielectric permittivity ɛ and magnetic permeability μ. Simultaneous negative ɛ and μ within a given frequency band of a metamaterial gives rise to a negative index of refraction n. This has been demonstrated via a Snell's law experiment. The electromagnetic properties of many metamaterial structures in the microwave region are investigated through numerical simulations and experiments. A negative index of refraction, n, allows lenses with reduced primary (Seidel) aberrations compared to equivalent positive index lens. This is demonstrated both for cylindrical lenses and spherical lenses, as well as for the gradient index lenses. Detailed field maps of the focal region of the metamaterials lenses are made and compared to a comparable positive index of refraction lens.

  10. Super-resolution imaging by one-dimensional, microwave left-handed metamaterials with an effective negative index

    International Nuclear Information System (INIS)

    Superlenses based on metamaterials are promising candidates for achieving subwavelength resolution. We report here our experimental studies on super-resolution imaging from one-dimensional (1D) negative index metamaterial superlenses at microwave frequencies. The metamaterial structure under investigation is shown to have a left-handed transmission band at frequencies where both effective permittivity and permeability are negative. The retrieved effective parameters are in good agreement with the measurements. We achieved a resolution of 0.2λ by imaging a single point source from a 1D superlens. Moreover, the effect of the superlens' thickness on the resolution is studied. A thicker superlens suffers from more losses, which in turn reduces the resolution. Two point sources that were separated by distances that were smaller than a half-wavelength were successfully resolved with the negative index superlens

  11. Super-resolution imaging by one-dimensional, microwave left-handed metamaterials with an effective negative index

    Energy Technology Data Exchange (ETDEWEB)

    Ozbay, Ekmel; Li, Zhaofeng; Aydin, Koray [Nanotechnology Research Center and Department of Physics, Bilkent University, Bilkent, 06800 Ankara (Turkey)], E-mail: ozbay@bilkent.edu.tr, E-mail: aydin@fen.bilkent.edu.tr

    2008-07-30

    Superlenses based on metamaterials are promising candidates for achieving subwavelength resolution. We report here our experimental studies on super-resolution imaging from one-dimensional (1D) negative index metamaterial superlenses at microwave frequencies. The metamaterial structure under investigation is shown to have a left-handed transmission band at frequencies where both effective permittivity and permeability are negative. The retrieved effective parameters are in good agreement with the measurements. We achieved a resolution of 0.2{lambda} by imaging a single point source from a 1D superlens. Moreover, the effect of the superlens' thickness on the resolution is studied. A thicker superlens suffers from more losses, which in turn reduces the resolution. Two point sources that were separated by distances that were smaller than a half-wavelength were successfully resolved with the negative index superlens.

  12. Super-resolution imaging by one-dimensional, microwave left-handed metamaterials with an effective negative index

    Science.gov (United States)

    Ozbay, Ekmel; Li, Zhaofeng; Aydin, Koray

    2008-07-01

    Superlenses based on metamaterials are promising candidates for achieving subwavelength resolution. We report here our experimental studies on super-resolution imaging from one-dimensional (1D) negative index metamaterial superlenses at microwave frequencies. The metamaterial structure under investigation is shown to have a left-handed transmission band at frequencies where both effective permittivity and permeability are negative. The retrieved effective parameters are in good agreement with the measurements. We achieved a resolution of 0.2λ by imaging a single point source from a 1D superlens. Moreover, the effect of the superlens' thickness on the resolution is studied. A thicker superlens suffers from more losses, which in turn reduces the resolution. Two point sources that were separated by distances that were smaller than a half-wavelength were successfully resolved with the negative index superlens.

  13. Negative index of refraction in a four-level system with magnetoelectric cross coupling and local field corrections

    International Nuclear Information System (INIS)

    This research focuses on a coherently driven four-level atomic medium with the aim of inducing a negative index of refraction while taking into consideration local field corrections as well as magnetoelectric cross coupling (i.e.,chirality) within the material's response functions. Two control fields are used to render the medium transparent for a probe field which simultaneously couples to an electric and a magnetic dipole transition, thus allowing one to test the permittivity and permeability of the material at the same time. Numerical simulations show that a negative index of refraction with low absorption can be obtained for a range of probe detunings while depending on number density and the ratio between the intensities of the control fields.

  14. Shear-mediated contributions to the effective properties of soft acoustic metamaterials including negative index

    OpenAIRE

    Derek Michael Forrester; Valerie J. Pinfield

    2015-01-01

    Here we show that, for sub-wavelength particles in a fluid, viscous losses due to shear waves and their influence on neighbouring particles significantly modify the effective acoustic properties, and thereby the conditions at which negative acoustic refraction occurs. Building upon earlier single particle scattering work, we adopt a multiple scattering approach to derive the effective properties (density, bulk modulus, wavenumber). We show,through theoretical prediction, the implications for ...

  15. A Miniaturized Antenna with Negative Index Metamaterial Based on Modified SRR and CLS Unit Cell for UWB Microwave Imaging Applications

    OpenAIRE

    Md. Moinul Islam; Mohammad Tariqul Islam; Md. Samsuzzaman; Mohammad Rashed Iqbal Faruque; Norbahiah Misran; Mohd Fais Mansor

    2015-01-01

    A miniaturized antenna employing a negative index metamaterial with modified split-ring resonator (SRR) and capacitance-loaded strip (CLS) unit cells is presented for Ultra wideband (UWB) microwave imaging applications. Four left-handed (LH) metamaterial (MTM) unit cells are located along one axis of the antenna as the radiating element. Each left-handed metamaterial unit cell combines a modified split-ring resonator (SRR) with a capacitance-loaded strip (CLS) to obtain a design architecture ...

  16. Dispersion, spatial growth rate, and start current of a Cherenkov free-electron laser with negative-index material

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yuanyuan; Wei, Yanyu; Jiang, Xuebing; Tang, Xianfeng; Shi, Xianbao; Gong, Yubin [National Key Laboratory of Science and Technology on Vacuum Electronics, School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054 (China); Li, Dazhi [Institute for Laser Technology, Suita, Osaka 565-0781 (Japan); Takano, Keisuke; Nakajima, Makoto [Institute of Laser Engineering, Osaka University, Suita, Osaka 565-0781 (Japan); Feng, Jinjun [Beijing Vacuum Electronics Research Institute, Beijing 100016 (China); Miyamoto, Shuji [Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Ako, Hyogo 678-1205 (Japan)

    2015-08-15

    We present an analysis of a Cherenkov free-electron laser based on a single slab made from negative-index materials. In this system, a flat electron beam with finite thickness travelling close to the surface of the slab interacts with the copropagating electromagnetic surface mode. The dispersion equation for a finitely thick slab is worked out and solved numerically to study the dispersion relation of surface modes supported by negative-index materials, and the calculations are in good agreement with the simulation results from a finite difference time domain code. We find that under suitable conditions there is inherent feedback in such a scheme due to the characteristics of negative-index materials, which means that the system can oscillate without external reflectors when the beam current exceeds a threshold value, i.e., start current. Using the hydrodynamic approach, we setup coupled equations for this system, and solve these equations analytically in the small signal regime to obtain formulas for the spatial growth rate and start current.

  17. Dispersion, spatial growth rate, and start current of a Cherenkov free-electron laser with negative-index material

    International Nuclear Information System (INIS)

    We present an analysis of a Cherenkov free-electron laser based on a single slab made from negative-index materials. In this system, a flat electron beam with finite thickness travelling close to the surface of the slab interacts with the copropagating electromagnetic surface mode. The dispersion equation for a finitely thick slab is worked out and solved numerically to study the dispersion relation of surface modes supported by negative-index materials, and the calculations are in good agreement with the simulation results from a finite difference time domain code. We find that under suitable conditions there is inherent feedback in such a scheme due to the characteristics of negative-index materials, which means that the system can oscillate without external reflectors when the beam current exceeds a threshold value, i.e., start current. Using the hydrodynamic approach, we setup coupled equations for this system, and solve these equations analytically in the small signal regime to obtain formulas for the spatial growth rate and start current

  18. Shear-mediated contributions to the effective properties of soft acoustic metamaterials including negative index

    Science.gov (United States)

    Forrester, Derek Michael; Pinfield, Valerie J.

    2015-12-01

    Here we show that, for sub-wavelength particles in a fluid, viscous losses due to shear waves and their influence on neighbouring particles significantly modify the effective acoustic properties, and thereby the conditions at which negative acoustic refraction occurs. Building upon earlier single particle scattering work, we adopt a multiple scattering approach to derive the effective properties (density, bulk modulus, wavenumber). We show,through theoretical prediction, the implications for the design of “soft” (ultrasonic) metamaterials based on locally-resonant sub-wavelength porous rubber particles, through selection of particle size and concentration, and demonstrate tunability of the negative speed zones by modifying the viscosity of the suspending medium. For these lossy materials with complex effective properties, we confirm the use of phase angles to define the backward propagation condition in preference to “single-” and “double-negative” designations.

  19. Two-dimensional fluid-filled closed-cell cellular solid as an acoustic metamaterial with negative index

    Science.gov (United States)

    Dorodnitsyn, V.; Van Damme, B.

    2016-04-01

    A concept for acoustic metamaterials consisting of a cellular medium with fluid-filled cells is fabricated and studied experimentally. In such a system, the fluid and solid structure explicitly interact, and elastic wave propagation is coupled to both phases. Focusing here on shear wave behavior, we confirm previous numerical studies in three steps. We first measure the material deformations pertaining to three qualitatively different shear wave modes in the frequency range below 3.5 kHz. We then measure the group velocity and demonstrate that, within a certain frequency interval, the group and phase velocity have opposite signs. This shows that the system acts as a negative-index metamaterial. Finally, we confirm the presence of band gaps due to the locally resonant behavior of the cell walls. The demonstrated concept of a closed, fluid-filled cellular material as an acoustic metamaterial opens a wide space for applications.

  20. Doped golden fullerene cages

    OpenAIRE

    Baletto, Francesca; Ferrando, Riccardo

    2015-01-01

    A first-principles investigation of the effect of the doping of golden cages of 32 atoms is proposed. It is shown that Ag and Cu doping affects the geometrical stability of the icosahedral fullerene Au-32 cage, where Ag-doping leads to a new, low symmetric, and prolate motif while Cu-doping leads to a lump, incomplete decahedral shape. Most significantly, the HOMO-LUMO gap depends strongly on the cluster geometry while its dependence on the cluster chemical composition seems to be weaker.

  1. Stabilizing a 22 karat nanogolden cage

    Science.gov (United States)

    Wang, Q.; Sun, Q.; Jena, P.

    2009-11-01

    Since the discovery of C60 fullerene, considerable efforts have been devoted to find other elements with similar hollow cage structures. However, search for hollow metallic cages with a diameter similar to that of C60 fullerene has been elusive. We describe a procedure for the rational design of metallic cages by suitably choosing their size, composition, and charge state. A 22 karat nanogolden cage with a diameter of about 8.5 Å and consisting of 12 Al and 20 Au atoms is found to be metastable, which can be stabilized by embedding a Mn4 cluster. In contrast to bulk Mn, which is antiferromagnetic, and isolated Mn4 cluster, which is ferromagnetic with a giant magnetic moment of 20μB, the Mn4@Al12Au20 endohedral complex exhibits magnetic bistability with 0μB and 14μB configurations being energetically nearly degenerate. These results, based on density functional theory, open the door to design a novel class of endohedral complexes with possible applications.

  2. 14C-age tracers in global ocean circulation models

    Science.gov (United States)

    Koeve, W.; Wagner, H.; Kähler, P.; Oschlies, A.

    2015-07-01

    The natural abundance of 14C in total CO2 dissolved in seawater (DIC) is a property applied to evaluate the water age structure and circulation in the ocean and in ocean models. In this study we use three different representations of the global ocean circulation augmented with a suite of idealised tracers to study the potential and limitations of using natural 14C to determine water age, which is the time elapsed since a body of water has been in contact with the atmosphere. We find that, globally, bulk 14C-age is dominated by two equally important components, one associated with ageing, i.e. the time component of circulation, and one associated with a "preformed 14C-age". The latter quantity exists because of the slow and incomplete atmosphere-ocean equilibration of 14C particularly in high latitudes where many water masses form. In the ocean's interior, preformed 14C-age behaves like a passive tracer. The relative contribution of the preformed component to bulk 14C-age varies regionally within a given model, but also between models. Regional variability in the Atlantic Ocean is associated with the mixing of waters with very different end members of preformed 14C-age. Here, variations in the preformed component over space and time mask the circulation component to an extent that its patterns are not detectable from bulk 14C-age. Between models, the variability of preformed 14C-age can also be considerable (factor of 2), related to the combination of physical model parameters, which influence circulation dynamics or gas exchange. The preformed component was found to be very sensitive to gas exchange and moderately sensitive to ice cover. In our model evaluation, the choice of the gas-exchange constant from within the currently accepted range of uncertainty had such a strong influence on preformed and bulk 14C-age that if model evaluation would be based on bulk 14C-age, it could easily impair the evaluation and tuning of a model's circulation on global and regional

  3. John Cage Discusses Fluxus.

    Science.gov (United States)

    Snyder, Ellsworth

    1992-01-01

    Presents an informal discussion with composer John Cage which includes his response to George Maciunas' work, his recollections of Marcel Duchamp, the complex relationship between inelegant material and revealing works of art, neo-Dada and neo-Fluxus, Wittgenstein and the artist's ultimate responsibility to initiate a change in the viewer or…

  4. Bulk metamaterials: Design, fabrication and characterization

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Alabastri, Alessandro;

    2009-01-01

    Bulk metamaterials claim a lot of attention worldwide. We report about our activity and advances in design, fabrication and characterization of metal-dielectric composites with three-dimensional lattices. The nomenclature of designs exhibiting negative index behaviour in the near infrared include......-layers-thick polymer woodpile photonic crystal. Characterization of such samples before and after metal deposition in the 700 nm 1700 nm range exposes some unpredictable features like an enhanced broadband transmission, which still waits to be explained.......Bulk metamaterials claim a lot of attention worldwide. We report about our activity and advances in design, fabrication and characterization of metal-dielectric composites with three-dimensional lattices. The nomenclature of designs exhibiting negative index behaviour in the near infrared includes...

  5. 14C-age tracers in global ocean circulation models

    Directory of Open Access Journals (Sweden)

    W. Koeve

    2014-10-01

    Full Text Available The natural abundance of 14C in total CO2 dissolved in seawater is a property applied to evaluate the water age structure and circulation in the ocean and in ocean models. In this study we use three different representations of the global ocean circulation augmented with a suite of idealised tracers to study the potential and limitations of using natural 14C to determine water age, the time elapsed since a body of water had contact with the atmosphere. We find that, globally, bulk 14C-age is dominated by two equally important components, one associated with aging, i.e. the time component of circulation and one associated with a "preformed 14C-age". This latter quantity exists because of the slow and incomplete atmosphere/ocean equilibration of 14C in particular in high latitudes where many water masses form. The relative contribution of the preformed component to bulk 14C-age varies regionally within a given model, but also between models. Regional variability, e.g. in the Atlantic Ocean is associated with the mixing of waters with very different end members of preformed 14C-age. In the Atlantic, variations in the preformed component over space and time mask the circulation component to an extent that its patterns are not detectable from bulk 14C-age alone. Between models the variability of age can also be considerable (factor of 2, related to the combinations of physical model parameters, which influence circulation dynamics, and gas exchange in the models. The preformed component was found to be very sensitive to gas exchange and moderately sensitive to ice cover. In our model evaluation exercise, the choice of the gas exchange constant from within the current range of uncertainty had such a strong influence on preformed and bulk 14C-age that if model evaluation would be based on bulk 14C-age it could easily impair the evaluation and tuning of a models circulation on global and regional scales. Based on the results of this study, we propose

  6. Building a better Faraday cage

    Science.gov (United States)

    MartinAlfven; Wright, David; skocpol; Rounce, Graham; Richfield, Jon; W, Nick; wheelsonfire

    2015-11-01

    In reply to the physicsworld.com news article “Are Faraday cages less effective than previously thought?” (15 September, http://ow.ly/SfklO), about a study that indicated, based on mathematical modelling, that conducting wire-mesh cages may not be as good at excluding electromagnetic radiation as is commonly assumed.

  7. Cage-based performance capture

    CERN Document Server

    Savoye, Yann

    2014-01-01

    Nowadays, highly-detailed animations of live-actor performances are increasingly easier to acquire and 3D Video has reached considerable attentions in visual media production. In this book, we address the problem of extracting or acquiring and then reusing non-rigid parametrization for video-based animations. At first sight, a crucial challenge is to reproduce plausible boneless deformations while preserving global and local captured properties of dynamic surfaces with a limited number of controllable, flexible and reusable parameters. To solve this challenge, we directly rely on a skin-detached dimension reduction thanks to the well-known cage-based paradigm. First, we achieve Scalable Inverse Cage-based Modeling by transposing the inverse kinematics paradigm on surfaces. Thus, we introduce a cage inversion process with user-specified screen-space constraints. Secondly, we convert non-rigid animated surfaces into a sequence of optimal cage parameters via Cage-based Animation Conversion. Building upon this re...

  8. A Negative Index Metamaterial-Inspired UWB Antenna with an Integration of Complementary SRR and CLS Unit Cells for Microwave Imaging Sensor Applications.

    Science.gov (United States)

    Islam, Mohammad Tariqul; Islam, Md Moinul; Samsuzzaman, Md; Faruque, Mohammad Rashed Iqbal; Misran, Norbahiah

    2015-01-01

    This paper presents a negative index metamaterial incorporated UWB antenna with an integration of complementary SRR (split-ring resonator) and CLS (capacitive loaded strip) unit cells for microwave imaging sensor applications. This metamaterial UWB antenna sensor consists of four unit cells along one axis, where each unit cell incorporates a complementary SRR and CLS pair. This integration enables a design layout that allows both a negative value of permittivity and a negative value of permeability simultaneous, resulting in a durable negative index to enhance the antenna sensor performance for microwave imaging sensor applications. The proposed MTM antenna sensor was designed and fabricated on an FR4 substrate having a thickness of 1.6 mm and a dielectric constant of 4.6. The electrical dimensions of this antenna sensor are 0.20 λ × 0.29 λ at a lower frequency of 3.1 GHz. This antenna sensor achieves a 131.5% bandwidth (VSWR sensors. PMID:26007721

  9. A Negative Index Metamaterial-Inspired UWB Antenna with an Integration of Complementary SRR and CLS Unit Cells for Microwave Imaging Sensor Applications

    OpenAIRE

    Mohammad Tariqul Islam; Md. Moinul Islam; Md. Samsuzzaman; Mohammad Rashed Iqbal Faruque; Norbahiah Misran

    2015-01-01

    This paper presents a negative index metamaterial incorporated UWB antenna with an integration of complementary SRR (split-ring resonator) and CLS (capacitive loaded strip) unit cells for microwave imaging sensor applications. This metamaterial UWB antenna sensor consists of four unit cells along one axis, where each unit cell incorporates a complementary SRR and CLS pair. This integration enables a design layout that allows both a negative value of permittivity and a negative value of permea...

  10. Biologically tunable reactivity of energetic nanomaterials using protein cages.

    Science.gov (United States)

    Slocik, Joseph M; Crouse, Christopher A; Spowart, Jonathan E; Naik, Rajesh R

    2013-06-12

    The performance of aluminum nanomaterial based energetic formulations is dependent on the mass transport, diffusion distance, and stability of reactive components. Here we use a biologically inspired approach to direct the assembly of oxidizer loaded protein cages onto the surface of aluminum nanoparticles to improve reaction kinetics by reducing the diffusion distance between the reactants. Ferritin protein cages were loaded with ammonium perchlorate (AP) or iron oxide and assembled with nAl to create an oxidation-reduction based energetic reaction and the first demonstration of a nanoscale biobased thermite material. Both materials showed enhanced exothermic behavior in comparison to nanothermite mixtures of bulk free AP or synthesized iron oxide nanopowders prepared without the use of ferritin. In addition, by utilizing a layer-by-layer (LbL) process to build multiple layers of protein cages containing iron oxide and iron oxide/AP on nAl, stoichiometric conditions and energetic performance can be optimized. PMID:23713514

  11. Blueprints for dodecahedral DNA cages

    International Nuclear Information System (INIS)

    Cage structures engineered from nucleic acids are of interest in nanotechnology, for example as a means of drug delivery (Destito et al 2007). Until now, most experimentally realized DNA cages have crystallographic symmetry, such as the shape of a cube (Chen and Seeman 1991 Nature 350 631-3), a tetrahedron (Goodman et al 2005 Science 310 1661-5), an octahedron (Shih et al 2004 Nature 427 618-21) or a truncated octahedron (Zhang and Seeman 1994 J. Am. Chem. Soc. 116 1661-9). Two examples of cages with non-crystallographic symmetry, a dodecahedron and a buckyball, have been realized recently (He et al 2008 Nature 452 198-201). A characteristic feature of these realizations is the fact that the cages are built from a number of identical building blocks called tiles: 20 for the case of the dodecahedron, and 60 for the case of the buckyball. We derive here a blueprint for the organization of nucleic acid in a dodecahedral cage such that the final product has a minimal number of strands. In particular, we show that a dodecahedral cage can be realized in terms of only two circular DNA molecules. We focus on the dodecahedral cage, because the volume to surface ratio of such a cage is larger than that of its crystallographic counterparts given the same fixed radial distance of the polyhedral vertices from the centre of the structure, whilst still requiring a smaller complexity than the truncated icosahedron (buckyball). We therefore expect that the dodecahedral DNA cages discussed here may be of interest in further applications in nanotechnology

  12. Intra-cage dynamics of molecular hydrogen confined in cages of two different dimensions of clathrate hydrates

    Science.gov (United States)

    Russina, Margarita; Kemner, Ewout; Mezei, Ferenc

    2016-01-01

    In porous materials the molecular confinement is often realized by means of weak Van der Waals interactions between the molecule and the pore surface. The understanding of the mechanism of such interactions is important for a number of applications. In order to establish the role of the confinement size we have studied the microscopic dynamics of molecular hydrogen stored in the nanocages of clathrate hydrates of two different dimensions. We have found that by varying the size of the pore the diffusive mobility of confined hydrogen can be modified in both directions, i.e. reduced or enhanced compared to that in the bulk solid at the same temperatures. In the small cages with a mean crystallographic radius of 3.95 Å the confinement reduces diffusive mobility by orders of magnitude. In contrast, in large cages with a mean radius of 4.75 Å hydrogen molecules displays diffusive jump motion between different equilibrium sites inside the cages, visible at temperatures where bulk H2 is solid. The localization of H2 molecules observed in small cages can promote improved functional properties valuable for hydrogen storage applications. PMID:27270444

  13. Intra-cage dynamics of molecular hydrogen confined in cages of two different dimensions of clathrate hydrates

    Science.gov (United States)

    Russina, Margarita; Kemner, Ewout; Mezei, Ferenc

    2016-06-01

    In porous materials the molecular confinement is often realized by means of weak Van der Waals interactions between the molecule and the pore surface. The understanding of the mechanism of such interactions is important for a number of applications. In order to establish the role of the confinement size we have studied the microscopic dynamics of molecular hydrogen stored in the nanocages of clathrate hydrates of two different dimensions. We have found that by varying the size of the pore the diffusive mobility of confined hydrogen can be modified in both directions, i.e. reduced or enhanced compared to that in the bulk solid at the same temperatures. In the small cages with a mean crystallographic radius of 3.95 Å the confinement reduces diffusive mobility by orders of magnitude. In contrast, in large cages with a mean radius of 4.75 Å hydrogen molecules displays diffusive jump motion between different equilibrium sites inside the cages, visible at temperatures where bulk H2 is solid. The localization of H2 molecules observed in small cages can promote improved functional properties valuable for hydrogen storage applications.

  14. Cage Clusters of Gold and Tin: Golden Buckyballs and Stannaspherene

    Science.gov (United States)

    Wang, Lai-Sheng

    2008-03-01

    Photoelectron spectroscopy (PES) yields direct electronic structure information for size-selected clusters. Combining PES with theoretical calculations has become an effective approach to obtain structural information for small and medium-sized clusters. We present recent discoveries of two classes of cage clusters in gold and tin. Negatively charged gold clusters (Aun^-) have been shown to exhibit a remarkable structural diversity from 2D structures for n = 4-12 and the pyramidal structure for n = 20. Using PES and DFT calculations, we have found that gold clusters with n = 16-18 possess unprecedented hollow cage structures. We have been able to successfully dope a variety of transition-metal atoms into the empty spaces in the golden cages, confirming their structural robustness, as well as demonstrating chemical tuning of their electronic, magnetic, and catalytic properties. Unlike carbon, the heavier congeners of the group 14 elements are not known to form hollow cage structures similar to the fullerenes. In PES studies of tin clusters, we noted that the spectrum of Sn12^- is distinctly different from that of its neighbors or its Si/Ge counterpart. This observation led to our discovery of a highly symmetric and stable icosahedral Sn12^2- cage, for which we coined a name ``stannaspherene'' to describe its high symmetry and spherical pi bonding. We have also shown that all transition metals including the f-block elements can be doped inside Sn12^2- to form a whole class of endohedral stannaspherenes, which may be used as potential building blocks for new cluster-assembled materials. In a preliminary experiment to synthesize stannaspherene in the bulk, a new cluster, Pd2@Sn18^4-, was crystallized and characterized, suggesting all stannaspherene and endohedral stannasphernes may be fabricated in the bulk under suitable conditions.

  15. An evaluation of intra-cage ventilation in three animal caging systems.

    Science.gov (United States)

    Keller, L S; White, W J; Snider, M T; Lang, C M

    1989-05-01

    Although temperature and relative humidity have been quantitated and their effects on research data studied, few studies have measured the air turnover rates at cage level. We evaluated the air distribution and air turnover rates in unoccupied shoe-box mouse cages, filter-top covered cages and shoe-box mouse cages housed in a flexible film isolator by using discontinuous gas chromatography/mass spectrometry and smoke. Results showed that air turnover was most rapid in the unoccupied shoe-box mouse cage and slowest in the filter-top covered cage. Placing mice in the filter-top covered cage did not significantly improve the air turnover rate. Although filter-top covered cages reduce cage-to-cage transmission of disease, the poor airflow observed within these cages could lead to a buildup of gaseous pollutants that may adversely affect the animal's health. PMID:2724925

  16. Cage culture of sea bass in Malaysia

    OpenAIRE

    1994-01-01

    The article discusses the cage culture practice of sea bass (Lates calcarifer) in Malaysia. Problems on feed and seed supply and overcrowding are also discussed. Despite these problems, seabass cage culture still continuously booms.

  17. DNA Cages with Icosahedral Symmetry in Bionanotechnology

    Science.gov (United States)

    Jonoska, Nataša; Taormina, Anne; Twarock, Reidun

    Blueprints for polyhedral cages with icosahedral symmetry made of circular DNA molecules are provided. The basic rule is that every edge of the cage is met twice in opposite directions by the DNA strand(s), and vertex junctions are realized by a set of admissible junction types. As nanocontainers for cargo storage and delivery, the icosidodecahedral cages are of special interest because they have the largest volume per surface ratio of all cages discussed here.

  18. A Mobile Phone Faraday Cage

    Science.gov (United States)

    French, M. M. J.

    2011-01-01

    A Faraday cage is an interesting physical phenomenon where an electromagnetic wave can be excluded from a volume of space by enclosure with an electrically conducting material. The practical application of this in the classroom is to block the signal to a mobile phone by enclosing it in a metal can. The background of the physics behind this is…

  19. Electronic cages for living cells.

    Science.gov (United States)

    Al Saeed, Sarah; Bakewell, David J

    2015-08-01

    Design and construction of an electronic cage is described which enables real-time manipulation of live and dead eukaryotic cells. Non-uniform, radio frequency (RF) AC electric fields are used to enable translational and rotational movement of cells, known as dielectrophoresis (DEP) and electro-rotation (EROT), and distinguish their state as viable and non-viable. A concentric multilayered mathematical model, applicable for eukaryotic cells, is also developed, coded and implemented. The simulations predict three dielectric dispersions in the DEP and EROT spectra, though in practice the third is very small so that two are observed. The cage is part of a multi-staged project incorporating controller and DEP/EROT digital signal generator and image processing. PMID:26736401

  20. Role of phase matching in pulsed second-harmonic generation: Walk-off and phase-locked twin pulses in negative-index media

    International Nuclear Information System (INIS)

    The present investigation is concerned with the study of pulsed second-harmonic generation under conditions of phase and group velocity mismatch, and generally low conversion efficiencies and pump intensities. In positive-index, nonmetallic materials, we generally find qualitative agreement with previous reports regarding the presence of a double-peaked second harmonic signal, which comprises a pulse that walks off and propagates at the nominal group velocity one expects at the second-harmonic frequency, and a second pulse that is 'captured' and propagates under the pump pulse. We find that the origin of the double-peaked structure resides in a phase-locking mechanism that characterizes not only second-harmonic generation, but also χ(3) processes and third-harmonic generation. The phase-locking mechanism that we describe occurs for arbitrarily small pump intensities, and so it is not a soliton effect, which usually relies on a threshold mechanism, although multicolor solitons display similar phase locking characteristics. Thus, in second harmonic generation a phase-matched component is always generated, even under conditions of material phase mismatch: This component is anomalous, because the material does not allow energy exchange between the pump and the second-harmonic beam. On the other hand, if the material is phase matched, phase locking and phase matching are indistinguishable, and the conversion process becomes efficient. We also report a similar phase-locking phenomenon in negative index materials. A spectral analysis of the pump and the generated signals reveals that the phase-locking phenomenon causes the forward moving, phase-locked second-harmonic pulse to experience the same negative index as the pump pulse, even though the index of refraction at the second-harmonic frequency is positive. Our analysis further shows that the reflected second-harmonic pulse generated at the interface and the forward-moving, phase-locked pulse appear to be part of the

  1. Polymers containing borane or carborane cage compounds and related applications

    Energy Technology Data Exchange (ETDEWEB)

    Bowen, III, Daniel E; Eastwood, Eric A

    2013-04-23

    Polymers comprising residues of cage compound monomers having at least one polyalkoxy silyl substituent are provided. The cage compound monomers are selected from borane cage compound monomers comprising at least 7 cage atoms and/or carborane cage compound monomers comprising 7 to 11 cage compound monomers. Such polymers can further comprise one or more reactive matrices and/or co-monomers covalently bound with the cage compound monomer residues. Articles of manufacture comprising such polymers are also disclosed.

  2. Cleaning Animals' Cages With Little Water

    Science.gov (United States)

    Harman, Benjamin J.

    1989-01-01

    Proposed freeze/thaw method for cleaning animals' cages requires little extra weight and consumes little power and water. Cleaning concept developed for maintaining experimental rat cages on extended space missions. Adaptable as well to similar use on Earth. Reduces cleaning time. Makes use of already available facilities such as refrigerator, glove box, and autoclave. Rat waste adheres to steel-wire-mesh floor of cage. Feces removed by loosening action of freezing-and-thawing process, followed by blast of air.

  3. Listening to Cage: Nonintentional philosophy and music

    Directory of Open Access Journals (Sweden)

    Richard Fleming

    2016-12-01

    Full Text Available Listening to Cage: Nonintentional Philosophy and Music threads together the writings of ordinary language philosophy and the music of John Cage, responding specifically to requests made by Cage and Stanley Cavell. While many texts downplay or ignore the philosophical demands in Cage’s music and other texts find grandiose spiritual and philosophical material tied to his work, this text rejects both efforts. It challenges the basic directions of the growing secondary source material on Cage, finding it largely contrary to what Cage himself and his music teaches. That secondary material constantly offers an intentional approach to the music which is to make Cage understandable or easier to understand. The present text makes him appropriately difficult and basically unapproachable, asking the reader for serious acknowledgment of what Cage says he does, namely, “I have nothing to say and I am saying it.” While there is little hope of stopping the Cage industry that academia and publishers have grown, this text wishes at least to try to slow it down. The footnotes of this text include direct conversation material with Cage from the 1980s and 1990s regarding many subjects—his own compositions, our life struggles, remarks on Wittgenstein, Thoreau, philosophy, and music—all with a new context for their hearing.

  4. Humidity and Cage and Bedding Temperatures in Unoccupied Static Mouse Caging after Steam Sterilization

    OpenAIRE

    Ward, Gina M; Cole, Kelly; Faerber, Jennifer; Hankenson, F Claire

    2009-01-01

    Contemporary rodent caging and equipment often are sterilized by steam autoclaves prior to use in facilities. This work assessed the microenvironment of unoccupied static mouse cages after steam sterilization to determine when internal temperatures had cooled to levels appropriate for rodent housing. Polycarbonate static cages containing food and corncob bedding were stacked (10 rows × 7 columns) in duplicate (front and back; n = 140 cages) on a storage truck and autoclaved to 249 °F (121 °C)...

  5. Hollow Gold Cages and Their Topological Relationship to Dual Fullerenes.

    Science.gov (United States)

    Trombach, Lukas; Rampino, Sergio; Wang, Lai-Sheng; Schwerdtfeger, Peter

    2016-06-20

    Golden fullerenes have recently been identified by photoelectron spectra by Bulusu et al. [S. Bulusu, X. Li, L.-S. Wang, X. C. Zeng, PNAS 2006, 103, 8326-8330]. These unique triangulations of a sphere are related to fullerene duals having exactly 12 vertices of degree five, and the icosahedral hollow gold cages previously postulated are related to the Goldberg-Coxeter transforms of C20 starting from a triangulated surface (hexagonal lattice, dual of a graphene sheet). This also relates topologically the (chiral) gold nanowires observed to the (chiral) carbon nanotubes. In fact, the Mackay icosahedra well known in gold cluster chemistry are related topologically to the dual halma transforms of the smallest possible fullerene C20 . The basic building block here is the (111) fcc sheet of bulk gold which is dual to graphene. Because of this interesting one-to-one relationship through Euler's polyhedral formula, there are as many golden fullerene isomers as there are fullerene isomers, with the number of isomers Niso increasing polynomially as O(Niso9 ). For the recently observed Au16- , Au17- , and Au18- we present simulated photoelectron spectra including all isomers. We also predict the photoelectron spectrum of Au32- . The stability of the golden fullerenes is discussed in relation with the more compact structures for the neutral and negatively charged Au12 to Au20 and Au32 clusters. As for the compact gold clusters we observe a clear trend in stability of the hollow gold cages towards the (111) fcc sheet. The high stability of the (111) fcc sheet of gold compared to the bulk 3D structure explains the unusual stability of these hollow gold cages. PMID:27244703

  6. Bulk undercooling

    Science.gov (United States)

    Kattamis, T. Z.

    1984-01-01

    Bulk undercooling methods and procedures will first be reviewed. Measurement of various parameters which are necessary to understand the solidification mechanism during and after recalescence will be discussed. During recalescence of levitated, glass-encased large droplets (5 to 8 mm diam) high speed temperature sensing devices coupled with a rapid response oscilloscope are now being used at MIT to measure local thermal behavior in hypoeutectic and eutectic binary Ni-Sn alloys. Dendrite tip velocities were measured by various investigators using thermal sensors or high speed cinematography. The confirmation of the validity of solidification models of bulk-undercooled melts is made difficult by the fineness of the final microstructure, the ultra-rapid evolution of the solidifying system which makes measurements very awkward, and the continuous modification of the microstructure which formed during recalescence because of precipitation, remelting and rapid coarsening.

  7. Active cage model of glassy dynamics.

    Science.gov (United States)

    Fodor, Étienne; Hayakawa, Hisao; Visco, Paolo; van Wijland, Frédéric

    2016-07-01

    We build up a phenomenological picture in terms of the effective dynamics of a tracer confined in a cage experiencing random hops to capture some characteristics of glassy systems. This minimal description exhibits scale invariance properties for the small-displacement distribution that echo experimental observations. We predict the existence of exponential tails as a crossover between two Gaussian regimes. Moreover, we demonstrate that the onset of glassy behavior is controlled only by two dimensionless numbers: the number of hops occurring during the relaxation of the particle within a local cage and the ratio of the hopping length to the cage size. PMID:27575182

  8. Compositions containing borane or carborane cage compounds and related applications

    Science.gov (United States)

    Bowen, III, Daniel E; Eastwood, Eric A

    2013-05-28

    Compositions comprising a polymer-containing matrix and a filler comprising a cage compound selected from borane cage compounds, carborane cage compounds, metal complexes thereof, residues thereof, mixtures thereof, and/or agglomerations thereof, where the cage compound is not covalently bound to the matrix polymer. Methods of making and applications for using such compositions are also disclosed.

  9. Compositions containing borane or carborane cage compounds and related applications

    Energy Technology Data Exchange (ETDEWEB)

    Bowen, III, Daniel E; Eastwood, Eric A

    2014-11-11

    Compositions comprising a polymer-containing matrix and a filler comprising a cage compound selected from borane cage compounds, carborane cage compounds, metal complexes thereof, residues thereof, mixtures thereof, and/or agglomerations thereof, where the cage compound is not covalently bound to the matrix polymer. Methods of making and applications for using such compositions are also disclosed.

  10. Compositions containing borane or carborane cage compounds and related applications

    Energy Technology Data Exchange (ETDEWEB)

    Bowen, III, Daniel E.; Eastwood, Eric A.

    2015-09-15

    Compositions comprising a polymer-containing matrix and a filler comprising a cage compound selected from borane cage compounds, carborane cage compounds, metal complexes thereof, residues thereof, mixtures thereof, and/or agglomerations thereof, where the cage compound is not covalently bound to the matrix polymer. Methods of making and applications for using such compositions are also disclosed.

  11. Synthesis of caged Garcinia xanthone analogues

    OpenAIRE

    Cho, Woo Cheal

    2009-01-01

    A new synthetic strategy is developed toward the synthesis of the caged Garcinia xanthone analogues. The key to the strategy is a Pd-catalyzed reverse prenylation reaction. This new synthetic approach provides a rapid and efficient access to various caged analogues, including cluvenone which is known to induce apoptosis and exhibit significant cytotoxicity in various cancer cell lines. Evaluation of their growth inhibitory activities also leads to identification of the pharmacophoric motif of...

  12. Welfare assessment of laying hens in furnished cages and non-cage systems: an on-farm comparison

    NARCIS (Netherlands)

    Rodenburg, T.B.; Tuyttens, F.; Reu, de K.; Herman, L.; Zoons, J.; Sonck, B.

    2008-01-01

    From 2012 onwards, all laying hens in Europe will need to be housed either in furnished cages or non-cage systems (aviaries or floor-housing systems). In terms of animal welfare, furnished cages and non-cage systems both have advantages and disadvantages. Data on direct comparisons between the two,

  13. Phosphonate Based High Nuclearity Magnetic Cages.

    Science.gov (United States)

    Sheikh, Javeed Ahmad; Jena, Himanshu Sekhar; Clearfield, Abraham; Konar, Sanjit

    2016-06-21

    Transition metal based high nuclearity molecular magnetic cages are a very important class of compounds owing to their potential applications in fabricating new generation molecular magnets such as single molecular magnets, magnetic refrigerants, etc. Most of the reported polynuclear cages contain carboxylates or alkoxides as ligands. However, the binding ability of phosphonates with transition metal ions is stronger than the carboxylates or alkoxides. The presence of three oxygen donor sites enables phosphonates to bridge up to nine metal centers simultaneously. But very few phosphonate based transition metal cages were reported in the literature until recently, mainly because of synthetic difficulties, propensity to result in layered compounds, and also their poor crystalline properties. Accordingly, various synthetic strategies have been followed by several groups in order to overcome such synthetic difficulties. These strategies mainly include use of small preformed metal precursors, proper choice of coligands along with the phosphonate ligands, and use of sterically hindered bulky phosphonate ligands. Currently, the phosphonate system offers a library of high nuclearity transition metal and mixed metal (3d-4f) cages with aesthetically pleasing structures and interesting magnetic properties. This Account is in the form of a research landscape on our efforts to synthesize and characterize new types of phosphonate based high nuclearity paramagnetic transition metal cages. We quite often experienced synthetic difficulties with such versatile systems in assembling high nuclearity metal cages. Few methods have been emphasized for the self-assembly of phosphonate systems with suitable transition metal ions in achieving high nuclearity. We highlighted our journey from 2005 until today for phosphonate based high nuclearity transition metal cages with V(IV/V), Mn(II/III), Fe(III), Co(II), Ni(II), and Cu(II) metal ions and their magnetic properties. We observed that

  14. Cage RACK ventilation options for laboratory animal facilities.

    Science.gov (United States)

    Stakutis, Richard E

    2003-09-01

    Individually ventilated cage systems have become the method of choice for housing rodents. The author describes the various options for cage ventilation, from using supply and exhaust fans to directly connecting the racks to the building ventilation system. PMID:12966448

  15. High-throughput Transcriptome analysis, CAGE and beyond

    KAUST Repository

    Kodzius, Rimantas

    2008-11-25

    1. Current research - PhD work on discovery of new allergens - Postdoctoral work on Transcriptional Start Sites a) Tag based technologies allow higher throughput b) CAGE technology to define promoters c) CAGE data analysis to understand Transcription - Wo

  16. Chemical contamination of animal feeding systems: evaluation of two caging systems and standard cage-washing equipment.

    Science.gov (United States)

    Fox, J G; Helfrich-Smith, M E

    1980-12-01

    Sodium fluorescein was added as a tracer to an ager gel diet which was fed for 5 day to 90 of 180 rats housed in two different polycarbonate caging systems, shoe-box cages and suspension solid-bottom cages. Cage racks, supplementary equipment, and case washer surfaces were analysed for fluorescein both before and after a complete wash and rinse cycle. Efficacy of washing was greater than 99% for both the inside and outside of the suspended cages and greater than 99% for the inside, but only 93% for the outside, of the shoe-box cages. The shoe-box cages, which were larger than the suspended cages, were spaced closer together on the washer rack, which may account for this variation in cleaning effectiveness. The cage washer surfaces and the water, which was recirculated during each cycle, also became contaminated with fluorescein. Strict adherence to proper cage-washing procedures and careful selection of cage design are important factors in controlling the potential for residual contamination of caging and cage-washing equipment. PMID:7464031

  17. Convective Cage Release in Model Colloidal Glasses.

    Science.gov (United States)

    Jacob, Alan R; Poulos, Andreas S; Kim, Sunhyung; Vermant, Jan; Petekidis, George

    2015-11-20

    The mechanism of flow in glassy materials is interrogated using mechanical spectroscopy applied to model nearly hard sphere colloidal glasses during flow. Superimposing a small amplitude oscillatory motion orthogonal onto steady shear flow makes it possible to directly evaluate the effect of a steady state flow on the out-of-cage (α) relaxation as well as the in-cage motions. To this end, the crossover frequency deduced from the viscoelastic spectra is used as a direct measure of the inverse microstructural relaxation time, during flow. The latter is found to scale linearly with the rate of deformation. The microscopic mechanism of flow can then be identified as a convective cage release. Further insights are provided when the viscoelastic spectra at different shear rates are shifted to scale the alpha relaxation and produce a strain rate-orthogonal frequency superposition, the colloidal analogue of time temperature superposition in polymers with the flow strength playing the role of temperature. Whereas the scaling works well for the α relaxation, deviations are observed both at low and high frequencies. Brownian dynamics simulations point to the origins of these deviations; at high frequencies these are due to the deformation of the cages which slows down the short-time diffusion, while at low frequency, deviations are most probably caused by some mild hydroclustering. PMID:26636876

  18. 50 CFR 648.75 - Cage identification.

    Science.gov (United States)

    2010-10-01

    ... are issued, or if rendered null and void in accordance with 15 CFR part 904. (d) Return. Tags that... Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION... Clam and Ocean Quahog Fisheries § 648.75 Cage identification. Except as provided in § 648.76,...

  19. An Easy Synthesis of Two Cage Hydrocarbons.

    Science.gov (United States)

    Dong, Dao Cong

    1982-01-01

    Describes a simple, three-step synthesis of two cage molecules, birdcage hydrocarbon (VIII) and its homologue, the homobirdcage hydrocarbon IX. Indicates that all products are easily purified and formed in high yields in this activity suitable for advanced undergraduate laboratory courses. (Author/JN)

  20. Porous Organic Cages for Sulfur Hexafluoride Separation.

    Science.gov (United States)

    Hasell, Tom; Miklitz, Marcin; Stephenson, Andrew; Little, Marc A; Chong, Samantha Y; Clowes, Rob; Chen, Linjiang; Holden, Daniel; Tribello, Gareth A; Jelfs, Kim E; Cooper, Andrew I

    2016-02-10

    A series of porous organic cages is examined for the selective adsorption of sulfur hexafluoride (SF6) over nitrogen. Despite lacking any metal sites, a porous cage, CC3, shows the highest SF6/N2 selectivity reported for any material at ambient temperature and pressure, which translates to real separations in a gas breakthrough column. The SF6 uptake of these materials is considerably higher than would be expected from the static pore structures. The location of SF6 within these materials is elucidated by X-ray crystallography, and it is shown that cooperative diffusion and structural rearrangements in these molecular crystals can rationalize their superior SF6/N2 selectivity. PMID:26757885

  1. Cathodic Cage Plasma Nitriding: An Innovative Technique

    OpenAIRE

    de Sousa, R. R. M.; de Araújo, F. O.; da Costa, J. A. P.; A. de S. Brandim; de Brito, R. A.; Alves, C

    2012-01-01

    Cylindrical samples of AISI 1020, AISI 316, and AISI 420 steels, with different heights, were simultaneously treated by a new technique of ionic nitriding, entitled cathodic cage plasma nitriding (CCPN), in order to evaluate the efficiency of this technique to produce nitrided layers with better properties compared with those obtained using conventional ionic nitriding technique. This method is able to eliminate the edge effect in the samples, promoting a better uniformity of temperature, and...

  2. Titanium mesh cages (TMC) in spine surgery

    OpenAIRE

    Grob, Dieter; Daehn, Sylvia; Mannion, Anne F.

    2004-01-01

    The introduction of the titanium mesh cage (TMC) in spinal surgery has opened up a variety of applications that are realizable as a result of the versatility of the implant. Differing applications of TMCs in the whole spine are described in a series of 150 patients. Replacement and reinforcement of the anterior column represent the classic use of cylindrical TMCs. The TMC as a multisegmental concave support in kyphotic deformities and as a posterior interlaminar spacer or lamina replacement a...

  3. Trace element kinetics in caged Mytilus galloprovincialis

    OpenAIRE

    Richir, Jonathan; Lepoint, Gilles; Donnay, Annick; Gobert, Sylvie

    2014-01-01

    Trace elements (TEs) remain contaminants of concern because of their persistence, ability to concentrate in organisms and toxicity. The Mediterranean mussel Mytilus galloprovincialis Lamarck, 1819 is a relevant bioindicator of TE coastal contamination. However, little research has studied the combined influence of environmental condition changes and physiological processes on their kinetics in that species. Caged M. galloprovincialis were thus immerged in 2 contrasted pristine Corsican (Franc...

  4. Biomechanische Untersuchungen von LWS-Cages

    OpenAIRE

    Gottwald, Maria

    2004-01-01

    Fragestellung: Cages sind Implantate, die der Fusionierung von Wirbelkörpern dienen. Zu ihren wichtigsten biomechanischen Eigenschaften gehört die Gewährleistung einer hohen Stabilität unmittelbar nach Implantation - der Primärstabilität -, die Aufrechterhaltung dieser Stabilität auch nach wiederholten Belastungen - Langzeitstabilität - und eine geringe Sinterungsneigung, worunter man das eindringen der Implantate in die angrenzenden Wirbelkörper versteht. Ziel dieser Arbeit war es nun zwe...

  5. The effect of pesticide residue on caged mosquito bioassays.

    Science.gov (United States)

    Barber, J A S; Greer, Mike; Coughlin, Jamie

    2006-09-01

    Wind tunnel experiments showed that secondary pickup of insecticide residue by mosquitoes in cage bioassays had a significant effect on mortality. Cage bioassays using adult Ochlerotatus taeniorhynchus (Wiedemann) investigated the effect of exposure time to a contaminated surface. Cages were dosed in a wind tunnel using the LC50 for naled (0.124 mg a.i./ml) and an LC25 (0.0772 mg a.i./ml) for naled. Half of the bioassay mosquitoes were moved directly into clean cages with the other half remaining in the sprayed, hence contaminated, cage. Treatment mortality was assessed at 8, 15, 30, 60, 120, 240, and 1,440 min postapplication. Cage contamination had a significant effect on mosquito mortality for both the LC25 and LC50 between 15 and 30 min postapplication. PMID:17067048

  6. A secure and economical system for caging venomous snakes

    OpenAIRE

    Powell, R. L.

    2003-01-01

    This paper describes an inexpensive and secure cage system for housing venomous snakes. The cages are easily constructed from commercially available plastic containers and are lightweight and can be stacked, minimizing the area needed to house numerous animals. They allow easy access to the animal and can be adequately disinfected. These cages can be individually locked and also allow for full viewing of the animal.

  7. PROBLEMS OF BIOFOULING ON FISH–CAGE NETS IN AQUACULTURE

    OpenAIRE

    Merica Slišković; Gorana Jelić

    2002-01-01

    Biofouling on fish–cage netting is a serious technical and economical problem to aquaculture worldwide. Compensation for the effects of biofouling must be included in cage system design and planning, as fouling can dramatically increase both weight and drag. Settlements of sessile plants and animals, with accumulation of the detritus diminish the size of mesh and can rapidly occlude mesh. Negative effect of smaller mesh size is changing in water flow trough the cages. Biofouling problems nece...

  8. THE PROCEDURE AND THE CRITERIA FOR FISH CAGES ALLOCATION

    OpenAIRE

    Valentina Andrić; Gordana Jelić Mrčelić; Merica Slišković; Ivana Miletić

    2010-01-01

    In the Republic of Croatia, fish cage farming is one of the most important economic activities. Fish cage farms inevitably influence the quality of marine environment. Environment protection measures are established in order to minimize negative effects on the stability of ecosystem. The aim of this paper is to give an overview on the procedure of fish cage farm allocation, environment protection measures, as also as program of monitoring before, during and after fish farming allocation.

  9. THE PROCEDURE AND THE CRITERIA FOR FISH CAGES ALLOCATION

    Directory of Open Access Journals (Sweden)

    Valentina Andrić

    2010-10-01

    Full Text Available In the Republic of Croatia, fish cage farming is one of the most important economic activities. Fish cage farms inevitably influence the quality of marine environment. Environment protection measures are established in order to minimize negative effects on the stability of ecosystem. The aim of this paper is to give an overview on the procedure of fish cage farm allocation, environment protection measures, as also as program of monitoring before, during and after fish farming allocation.

  10. Advanced behavioural screening: automated home cage ethology.

    Science.gov (United States)

    Spruijt, Berry M; DeVisser, Leonie

    2006-01-01

    Animal behaviour has been studied using two approaches, (1) well-controlled experiments focusing on specific responses and (2) those with natural - fuzzy - but biologically relevant conditions. Ideally, one behavioural test should be able to address both. The home cage provided with various stimuli is proposed as an all-in-one possibility. This, however, results in an exponential increase in complexity regarding observation and analysis tools. It seems difficult to accept that behavioural expressions need a mathematical approach to unravel its organisation and meaning. Developments in artificial intelligence and data mining are essential to accelerate this necessary evolution in behavioural sciences.: PMID:24980412

  11. Influence of metabolic cage on Wistar rat physiological state

    Directory of Open Access Journals (Sweden)

    Judita Zymantiene

    2016-03-01

    Full Text Available The aim of this study was to investigate the influence of metabolic cage housing on the Wistar rat physiological state and to analyze the correlation between the minerals in blood and urine. Thirty male rats were used in the experiment. Fifteen rats (control group were housed individually in standard polycarbonate cages and fifteen rats (experimental group in metabolic cages (Techniplast, Italy for two weeks. Body weight, respiration rate, water and food consumptions were recorded for each animal at the beginning of the experiment. The same parameters, as well as blood and urine parameters of control and experimental animals were recorded during the experiment after 72 h, 168 h and 336 h of housing in standard cages and metabolic cages. Urine collection was measured only in the experimental group. Rats weight decreased from 3.84 % to 18.59 % (P<0.05, respiration rate from 18.65 % to 24.59 % (P<0.05 when rats were housed in metabolic cages. Consumption of food and water by the rat depended on how long the animal was kept in metabolic cage. Glucose concentration increased on average by 15.37 %, WBC count decreased by 5.83 % in the blood of rats housed in metabolic cages compared to the animals housed in standard cages. We did not observe significant changes of triglycerides concentration, red blood cells count and total protein between all rats. The positive moderate correlation of rat housing in a metabolic cage was between K blood and K urine, P blood and P urine, Na blood and K blood, between Na urine and P urine and significant negative moderate correlation was determined between K urine and P urine. These present study findings indicate that metabolism cage housing significantly affects rat’s physiological parameters and potentially may influence animal health and well being.

  12. Computed tomography measurement of rib cage morphometry in emphysema.

    Directory of Open Access Journals (Sweden)

    Nicola Sverzellati

    Full Text Available BACKGROUND: Factors determining the shape of the human rib cage are not completely understood. We aimed to quantify the contribution of anthropometric and COPD-related changes to rib cage variability in adult cigarette smokers. METHODS: Rib cage diameters and areas (calculated from the inner surface of the rib cage in 816 smokers with or without COPD, were evaluated at three anatomical levels using computed tomography (CT. CTs were analyzed with software, which allows quantification of total emphysema (emphysema%. The relationship between rib cage measurements and anthropometric factors, lung function indices, and %emphysema were tested using linear regression models. RESULTS: A model that included gender, age, BMI, emphysema%, forced expiratory volume in one second (FEV1%, and forced vital capacity (FVC% fit best with the rib cage measurements (R(2 = 64% for the rib cage area variation at the lower anatomical level. Gender had the biggest impact on rib cage diameter and area (105.3 cm(2; 95% CI: 111.7 to 98.8 for male lower area. Emphysema% was responsible for an increase in size of upper and middle CT areas (up to 5.4 cm(2; 95% CI: 3.0 to 7.8 for an emphysema increase of 5%. Lower rib cage areas decreased as FVC% decreased (5.1 cm(2; 95% CI: 2.5 to 7.6 for 10 percentage points of FVC variation. CONCLUSIONS: This study demonstrates that simple CT measurements can predict rib cage morphometric variability and also highlight relationships between rib cage morphometry and emphysema.

  13. Preinjector for Linac 1, Faraday cage

    CERN Multimedia

    1974-01-01

    The 50 MeV Linac 1 started up in 1958 as injector to the 26 GeV PS, with a 520 kV Cockcroft-Walton generator as its preinjector, housed in a vast Faraday cage, visible here. When the Cockcroft-Walton broke down in 1973, it was replaced by a much smaller SAMES generator, of the kind used for electrostatic separators. From 1980 on, Linac 2 took over as injector for the 800 MeV Booster, and Linac 1 continued as injector for LEAR. In 1984, the electrostatic preinjector (i.e. the Faraday cage with its contents, SAMES generator and all) was replaced by a 520 keV RFQ. At the lower left corner we see the HV connectors to the SAMES generator, at the right edge part of the opened electronics-platform. Jean-Luc Vallet sees to it that all parts are properly grounded. See also 7403073X, 7403074X, 7403081X, 7403083X.

  14. Morphosynthesis of cubic silver cages on monolithic activated carbon.

    Science.gov (United States)

    Wang, Fei; Zhao, Hong; Lai, Yijian; Liu, Siyu; Zhao, Binyuan; Ning, Yuesheng; Hu, Xiaobin

    2013-11-14

    Cubic silver cages were prepared on monolithic activated carbon (MAC) pre-absorbed with Cl(-), SO4(2-), or PO4(3-) anions. Silver insoluble salts served as templates for the morphosynthesis of silver cages. The silver ions were reduced by reductive functional groups on MAC micropores through a galvanic cell reaction mechanism. PMID:24080952

  15. 48 CFR 204.7202-1 - CAGE codes.

    Science.gov (United States)

    2010-10-01

    ...)(1) If a prospective contractor located in the United States must register in the Central Contractor... registrants must obtain a North Atlantic Treaty Organization CAGE (NCAGE) code in order to register in the CCR... dial-up capability; or (D) The Internet to access the CAGE Lookup Server at...

  16. Design of the UHVDC Corona Cage in China

    Institute of Scientific and Technical Information of China (English)

    GUO Jian; LU Jiayu; ZHANG Wenliang

    2013-01-01

    For the purpose of testing and analysing the corona characteristics of UHVDC bundle conductors,UHVDC corona cage would be built in China.Corona cage is one of the indispensable equipments for conductor corona performance researches.Tests of conductor cotona characteristics in corona cages can overcome the shortages of those with test lines.The dimensions of several corona cages constructed overseas were introduced in this paper.Based on foreign experiences and the requirement of State Grid Corporation of China,the UHVDC corona cage was designed as double-cage,double-layer,three-seetions,and catenary shape with the size of 70 m×22 m× 13 m.The corona loss measurement system,radio interference measuring system,and the audible noise measuring system are also detailed,including the measurement theory,connection with the cage,the parameters and the designing basis.The UHVDC corona cage has been put into service.It now undergoes a large amount of audible noise and radio frequency interference tests.

  17. Abnormal Behavior in Relation to Cage Size in Rhesus Monkeys

    Science.gov (United States)

    Paulk, H. H.; And Others

    1977-01-01

    Examines the effects of cage size on stereotyped and normal locomotion and on other abnormal behaviors in singly caged animals, whether observed abnormal behaviors tend to co-occur, and if the development of an abnormal behavior repertoire leads to reduction in the number of normal behavior categories. (Author/RK)

  18. Polymers containing borane or carborane cage compounds and related applications

    Science.gov (United States)

    Bowen, III, Daniel E.; Eastwood, Eric A.

    2012-06-05

    Polymers comprising residues of borane and/or carborane cage compound monomers having at least one polyalkoxy silyl substituent. Such polymers can further comprise one or more reactive matrices and/or co-monomers covalently bound with the cage compound monomer residues. Methods of making and applications for using such polymers are also disclosed.

  19. Ammonia Levels and Urine-Spot Characteristics as Cage-Change Indicators for High-Density Individually Ventilated Mouse Cages.

    Science.gov (United States)

    Washington, Ida M; Payton, Mark E

    2016-01-01

    Mouse cage and bedding changes are potentially stressful to mice and are also labor- and resource-intensive. These changes are often performed on a calendar-based schedule to maintain a clean microenvironment and limit the concentrations of ammonia to which mice and workers are exposed. The current study sought to establish a performance-based approach to mouse cage-changing that uses urine spot characteristics as visual indicators of intracage ammonia levels. Colorimetric ammonia indicators were used to measure ammonia levels in individually-ventilated cages (IVC) housing male or female mice (n =5 per cage) of various strains at 1 to 16 d after cage change. Urine spot characteristics were correlated with ammonia levels to create a visual indicator of the cage-change criterion of 25 ppm ammonia. Results demonstrated a consistent increase in ammonia levels with days since cage change, with cages reaching the cage-change criterion at approximately 10 d for IVC containing male mice and 16 d for those with female mice. Ammonia levels were higher for male than female mice but were not correlated with mouse age. However, urine spot diameter, color, and edge characteristics were strongly correlated with ammonia levels. Husbandry practices based on using urine spot characteristics as indicators of ammonia levels led to fewer weekly cage changes and concomitant savings in labor and resources. Therefore, urine spot characteristics can be used as visual indicators of intracage ammonia levels for use of a performance (urine spot)-based approach to cage-changing frequency that maintains animal health and wellbeing. PMID:27177558

  20. Electrofriction method of manufacturing squirrel cage rotors

    Science.gov (United States)

    Hsu, John S.

    2005-04-12

    A method of making a squirrel cage rotor of copper material for use in AC or DC motors, includes forming a core with longitudinal slots, inserting bars of conductive material in the slots, with ends extending out of opposite ends of the core, and joining the end rings to the bars, wherein the conductive material of either the end rings or the bars is copper. Various methods of joining the end rings to the bars are disclosed including electrofriction welding, current pulse welding and brazing, transient liquid phase joining and casting. Pressure is also applied to the end rings to improve contact and reduce areas of small or uneven contact between the bar ends and the end rings. Rotors made with such methods are also disclosed.

  1. Protein Cages as Containers for Gold Nanoparticles.

    Science.gov (United States)

    Liu, Aijie; Verwegen, Martijn; de Ruiter, Mark V; Maassen, Stan J; Traulsen, Christoph H-H; Cornelissen, Jeroen J L M

    2016-07-01

    Abundant and highly diverse, viruses offer new scaffolds in nanotechnology for the encapsulation, organization, or even synthesis of novel materials. In this work the coat protein of the cowpea chlorotic mottle virus (CCMV) is used to encapsulate gold nanoparticles with different sizes and stabilizing ligands yielding stable particles in buffered solutions at neutral pH. The sizes of the virus-like particles correspond to T = 1, 2, and 3 Caspar-Klug icosahedral triangulation numbers. We developed a simple one-step process enabling the encapsulation of commercially available gold nanoparticles without prior modification with up to 97% efficiency. The encapsulation efficiency is further increased using bis-p-(sufonatophenyl)phenyl phosphine surfactants up to 99%. Our work provides a simplified procedure for the preparation of metallic particles stabilized in CCMV protein cages. The presented results are expected to enable the preparation of a variety of similar virus-based colloids for current focus areas. PMID:27135176

  2. Cathodic Cage Plasma Nitriding: An Innovative Technique

    Directory of Open Access Journals (Sweden)

    R. R. M. de Sousa

    2012-01-01

    Full Text Available Cylindrical samples of AISI 1020, AISI 316, and AISI 420 steels, with different heights, were simultaneously treated by a new technique of ionic nitriding, entitled cathodic cage plasma nitriding (CCPN, in order to evaluate the efficiency of this technique to produce nitrided layers with better properties compared with those obtained using conventional ionic nitriding technique. This method is able to eliminate the edge effect in the samples, promoting a better uniformity of temperature, and consequently, a smaller variation of the thickness/height relation can be obtained. The compound layers were characterized by X-ray diffraction, optical microscopy, and microhardness test profile. The results were compared with the properties of samples obtained with the conventional nitriding, for the three steel types. It was verified that samples treated by CCPN process presented, at the same temperature, a better uniformity in the thickness and absence of the edge effect.

  3. Transcription regulatory networks analysis using CAGE

    KAUST Repository

    Tegnér, Jesper N.

    2009-10-01

    Mapping out cellular networks in general and transcriptional networks in particular has proved to be a bottle-neck hampering our understanding of biological processes. Integrative approaches fusing computational and experimental technologies for decoding transcriptional networks at a high level of resolution is therefore of uttermost importance. Yet, this is challenging since the control of gene expression in eukaryotes is a complex multi-level process influenced by several epigenetic factors and the fine interplay between regulatory proteins and the promoter structure governing the combinatorial regulation of gene expression. In this chapter we review how the CAGE data can be integrated with other measurements such as expression, physical interactions and computational prediction of regulatory motifs, which together can provide a genome-wide picture of eukaryotic transcriptional regulatory networks at a new level of resolution. © 2010 by Pan Stanford Publishing Pte. Ltd. All rights reserved.

  4. Performance and welfare of rabbit does in various caging systems.

    Science.gov (United States)

    Mikó, A; Matics, Zs; Gerencsér, Zs; Odermatt, M; Radnai, I; Nagy, I; Szendrő, K; Szendrő, Zs

    2014-07-01

    The objective of the study was to compare production and welfare of rabbit does and their kits housed in various types of cages. Female rabbits were randomly allocated to four groups with the following cage types: CN: common wire-mesh flat-deck cage, without footrest; CF: cage similar to the CN but with plastic footrest; ECWP: enlarged cage with wire-mesh platform; and ECPP: extra enlarged cage with plastic-mesh platform. All does were inseminated on the same day, 11 days after kindlings. Reproductive performance was evaluated during the first five consecutive kindlings. Severity of sore hocks was scored at each insemination. Location preference of the does and the platform usage of their kits were evaluated. Kindling rate, litter size (total born, born alive, alive at 21 and 35 days) and kit mortality were not significantly influenced by the cage types. The litter weight at 21 days was higher in ECWP and ECPP cages than in the CF group (3516, 3576 and 3291 g, respectively; P2.5 cm) and 3 to 4 (3=callus opened, cracks present; 4=wounds) were 58%, 60%, 78% and 48%, and 0%, 5%, 0% and 48% in groups ECPP, ECWP, CF and CN, respectively. Higher number of daily nest visits was observed for CF does than for ECWP does (12.5 v. 5.9; P2/day) was higher in the CF group than in the ECWP group (12.1 v. 3.2%; Pplastic footrests and plastic-mesh platforms in conventional and/or large cages reduced sore hocks' problems, plastic-mesh platforms were more used by both does and kits compared with the wire-mesh platforms. PMID:26263030

  5. Endohedral dynamics of push-pull rotor-functionalized cages.

    Science.gov (United States)

    Krick, Marcel; Holstein, Julian; Würtele, Christian; Clever, Guido H

    2016-08-16

    A series of [Pd2L4] coordination cages featuring endohedral functionalities in central backbone positions was synthesized. Although attached via C[double bond, length as m-dash]C double bonds, the substituents behave as molecular rotors. This is explained by their pronounced donor-acceptor character which lowers rotational barriers and allows for electronic control over the spinning rates inside the cage. The dynamic behaviour of the free ligands, assembled cages and host-guest complexes is compared with the aid of NMR experiments, X-ray structure analysis and molecular modelling. PMID:27484435

  6. The planimetric unfold method of fullerene cage structure

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Two kinds of planimetric diagrams, which consist of the boat form F6 and F5, the storm petrel form F6 and F5, respectively, were proposed to express the geometric structure of fullerene cage in this study. There are two chief advantages using the diagrams: (ⅰ) the spatial symmetrical characteristic of fullerene cage is not destroyed; (ⅱ) the coordination forms of F5 and F6 in the structure can be clearly expressed. This work has laid the foundation for studying the structural geometry of fullerene cage and its quantum chemistry and property.

  7. Bemisia tabaci: A new clip-cage for biological studies

    OpenAIRE

    Muñiz, M.; Nombela, G.

    2001-01-01

    This new clip-cage has been designed in our laboratory. It is a transparent plastic truncated cone clip-cage (3.6 cm x 2.6 cm diameter; 4 cm high). A very thin polypropylene mesh (30 holes/inch) is attached to the bottom by paraffin wax. We have used this clip-cage attached to the under surface of the leaves in our studies on the biology of both B and Q biotypes of Bemisia tabaci with excellent results.

  8. Linear diffusion into a Faraday cage.

    Energy Technology Data Exchange (ETDEWEB)

    Warne, Larry Kevin; Lin, Yau Tang; Merewether, Kimball O.; Chen, Kenneth C.

    2011-11-01

    Linear lightning diffusion into a Faraday cage is studied. An early-time integral valid for large ratios of enclosure size to enclosure thickness and small relative permeability ({mu}/{mu}{sub 0} {le} 10) is used for this study. Existing solutions for nearby lightning impulse responses of electrically thick-wall enclosures are refined and extended to calculate the nearby lightning magnetic field (H) and time-derivative magnetic field (HDOT) inside enclosures of varying thickness caused by a decaying exponential excitation. For a direct strike scenario, the early-time integral for a worst-case line source outside the enclosure caused by an impulse is simplified and numerically integrated to give the interior H and HDOT at the location closest to the source as well as a function of distance from the source. H and HDOT enclosure response functions for decaying exponentials are considered for an enclosure wall of any thickness. Simple formulas are derived to provide a description of enclosure interior H and HDOT as well. Direct strike voltage and current bounds for a single-turn optimally-coupled loop for all three waveforms are also given.

  9. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-12-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  10. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-01-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  11. Evaluation of the pharmacophoric motif of the caged Garcinia xanthones†

    OpenAIRE

    Chantarasriwong, Oraphin; Cho, Woo Cheal; Batova, Ayse; Chavasiri, Warinthorn; Moore, Curtis; Rheingold, Arnold L.; Theodorakis, Emmanuel A.

    2009-01-01

    The combination of unique structure and potent bioactivity exhibited by several family members of the caged Garcinia xanthones, led us to evaluate their pharmacophore. We have developed a Pd(0)-catalyzed method for the reverse prenylation of catechols that, together with a Claisen/Diels–Alder reaction cascade, provides rapid and efficient access to various caged analogues. Evaluation of the growth inhibitory activity of these compounds leads to the conclusion that the intact ABC ring system c...

  12. Cage experiments in an East African mangrove forest: a synthesis

    OpenAIRE

    Schrijvers, J.; Vincx, M.

    1997-01-01

    The impact of epibenthos on endobenthos has frequently been investigated for temperate saltmarsh regions by using cage exclusion experiments. Although the insight into the function of the endobenthos of mangrove forests is crucial for their management, very few cage experiments have so far been carried out in such areas. The present paper summarises the result of such experiments in a typical East African mangrove forest at Gazi Bay about 60 km south of Mombasa, Kenya. Epibenthic animals were...

  13. Catalogue Note on Taner Ceylan's Cage of Flesh (2012)

    OpenAIRE

    Cakirlar, C.; Delice, S.

    2012-01-01

    Cage of Flesh (Ten Kafesi), the most recent piece by the photorealist painter Taner Ceylan, engages with the politics of and the erotics within representation in Orientalist painting by confronting the viewer with a re-imagined figure of an odalisque. Following his highly acclaimed Lost Painting Series that featured Fake World (2011), 1640 (2011), 1879 (2011), 1923 (2010) and 1881 (2010), Cage of Flesh uses an ingenious amalgam of allusions to both Orientalist eroticisation of female flesh an...

  14. Experimental setup for the measurement of induction motor cage currents

    International Nuclear Information System (INIS)

    An experimental setup for measurement of the currents flowing in the rotor bars of induction motors during synchronous no-load tests is described in the paper. The experimental verification of the high-frequency phenomena in the rotor cage is fundamental for a deep insight of the additional loss estimation by numerical methods. The attention is mainly focused on the analysis and design of the transducers developed for the cage current measurement

  15. Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor.

    Science.gov (United States)

    Perdicakis, Basil; Montgomery, Heather J; Abbott, Glenn L; Fishlock, Dan; Lajoie, Gilles A; Guillemette, J Guy; Jervis, Eric

    2005-01-01

    Over the past decade, multiphoton microscopy has progressed from a photonic novelty to a technique whose application is currently experiencing exponential growth in the biological sciences. A novel application of this technology with significant therapeutic potential is the control of drug activity by multiphoton photolysis of caged therapeutics. As an initial case study, the potent isoform selective inhibitor N-(3-(aminomethyl)benzyl) acetamidine (1400W) of inducible nitric oxide synthase (iNOS) has been conjugated to a caging molecule 6-bromo-7-hydroxy-4-hydroxyquinoline-2-ylmethyl acetyl ester (Bhc). Here we present the first report of a bulk therapeutic effect, inhibition of nitric oxide production, in mammalian cell culture by multiphoton photolysis of a caged drug, Bhc-1400W. Mouse macrophage RAW 264.7 cells induced with bacterial lipopolysaccharides to express iNOS were used to assess the therapeutic value of the conjugated inhibitor. Both 1400W and Bhc-1400W are stable in metabolically active cells and an optimal time interval for the photorelease of the inhibitor was determined. The ratios of the IC(50) values of Bhc-1400W over 1400W calculated in the presence of iNOS enzyme and in RAW 264.7 cell culture are 19 and 100, respectively, indicating that a broad therapeutic range exists in cell culture. Multiphoton uncaging protocols and therapeutic doses of inhibitors were not cytotoxic. Photocontrol of LPS induced nitric oxide production was achieved in mammalian cell culture using a single laser focal volume. This technology has the potential to control active drug concentrations in vivo, a lack of which is one of the main problems currently associated with systemic drug administration. PMID:15582451

  16. Anterior cervical discectomy and fusion: Comparison of titanium and polyetheretherketone cages

    OpenAIRE

    Cabraja Mario; Oezdemir Soner; Koeppen Daniel; Kroppenstedt Stefan

    2012-01-01

    Abstract Background Titanium (TTN) cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK) cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical discectomy and fusion (ACDF) and therefore might lead to a higher loss of correction. We compared the long term results of stand-alone PEEK- and TTN-cages in a comparable patient collective that was operated under identical operative settings. Methods From 2002 to 2007 15...

  17. Evaluation of individually ventilated cage systems for laboratory rodents: cage environment and animal health aspects.

    Science.gov (United States)

    Höglund, A U; Renström, A

    2001-01-01

    The use of individually ventilated cage (IVC) systems has become an attractive housing regime of laboratory rodents. The benefits of IVC systems are, reportedly, a high degree of containment combined with relative ease of handling, and a high degree of protection from allergenes. In the present study we tested whether two IVC systems (BioZone VentiRack, IVC1 and Techniplast SealSafe, IVC2S), in which we held mature male NMRI mice, were constructed to maintain a constant differential pressure, positive or negative, during a prolonged period of time. We also measured ammonia (NH3) concentrations after about 2 weeks of use, and CO2 build-up during a 60 min simulated power failure situation. In addition, animal weight development and bite-wound frequency were recorded (Renström et al. 2000). From the present study it is concluded that the IVC1 air handling system provides a more uniform and balanced differential pressure than the IVC2S. Both systems effectively scavenge NH3 when bedding material is not soaked by urine. Although the IVCs are dependent on the continual function of the fans to work properly, it seems unlikely that CO2 concentrations increase to hazardous levels, as a result of a one hour power failure, with the type of cages used in this study. Differences in weight development and bite-wound occurrence were noted between the two IVC systems. Causes for these differences could not be established and need more investigation. PMID:11201288

  18. Multicomponent Protein Cage Architectures for Photocatalysis

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Arunava [Univ. of Alabama, Tuscaloosa, AL (United States); Prevelige, Peter E [Univ. of Alabama, Birmingham, AL (United States)

    2016-01-04

    The primary goal of the project was to develop protein-templated approaches for the synthesis and directed assembly of semiconductor nanomaterials that are efficient for visible light absorption and hydrogen production. In general, visible-light-driven photocatalysis reactions exhibit low quantum efficiency for solar energy conversion primarily because of materials-related issues and limitations, such as the control of the band gap, band structure, photochemical stability, and available reactive surface area of the photocatalyst. Synthesis of multicomponent hierarchical nano-architectures, consisting of semiconductor nanoparticles (NPs) with desired optical properties fabricated to maximize spatial proximity for optimum electron and energy transfer represents an attractive route for addressing the problem. Virus capsids are highly symmetrical, self-assembling protein cage nanoparticles that exist in a range of sizes and symmetries. Selective deposition of inorganic, by design, at specific locations on virus capsids affords precise control over the size, spacing, and assembly of nanomaterials, resulting in uniform and reproducible nano-architectures. We utilized the self-assembling capabilities of the 420 subunit, 60 nm icosahedral, P22 virus capsid to direct the nucleation, growth, and proximity of a range of component materials. Controlled fabrication on the exterior of the temperature stable shell was achieved by genetically encoding specific binding peptides into an externally exposed loop which is displayed on each of the 420 coat protein subunits. Localization of complimentary materials to the interior of the particle was achieved through the use “scaffolding-fusion proteins. The scaffolding domain drives coat protein polymerization resulting in a coat protein shell surrounding a core of approximately 300 scaffolding/fusion molecules. The fusion domain comprises a peptide which specifically binds the semiconductor material of interest.

  19. CAGE BREEDING OF WARM WATER FRESHWATER FISH SPECIES

    Directory of Open Access Journals (Sweden)

    Roman Safner

    2008-10-01

    Full Text Available In the 1970s, Croatia became actively involved in the contemporary trend of breeding fish in floating cages. In addition to various species of marine fishes, breeding was attempted with trout, carp, catfish, cisco and salmon. Of the above freshwater fish species, specific standards were established only for the cage breeding of rainbow trout. Cage breeding of the remaining species remained at the level of occasional attempts, with more of an experimental than a commercial character. The regular attempts to master this technique for cage breeding of warm water freshwater fish species were aimed at achieving the known benefits of such breeding, such as simplicity of implementing technological measures, easier establishment of the breeding system, simpler manipulation, the possibility of denser colonies per unit volume with a high level of production, easier adaptations to market conditions and fewer initial structural investments. Despite the many advantages, the main reasons for the lack of greater implementation of the cage breeding technology for warm water species of freshwater fish include problems in obtaining the appropriate category and quantity of healthy fry, the specificity and applicability of physical and chemical properties of the recipients and human error. In evaluating the advantages and disadvantages, the final decision on the justification of cage breeding for individual warm water freshwater species must be based on both biological and economic factors. Based on the knowledge of cage breeding acquired to date, the rule for virtually all intensive breeding systems is that it is only recommended for those species with high market demand and a high market price. The technology that demands nutrition with highly concentrated feed and other production expenditures is costly, and is therefore not profitable with less expensive fish species. Furthermore, production must be market oriented, i.e. the appropriate market research measures

  20. Bulk chemicals from biomass

    NARCIS (Netherlands)

    Haveren, van J.; Scott, E.L.; Sanders, J.P.M.

    2008-01-01

    Given the current robust forces driving sustainable production, and available biomass conversion technologies, biomass-based routes are expected to make a significant impact on the production of bulk chemicals within 10 years, and a huge impact within 20-30 years. In the Port of Rotterdam there is a

  1. Ferromagnetic bulk glassy alloys

    International Nuclear Information System (INIS)

    This paper deals with the review on the formation, thermal stability and magnetic properties of the Fe-based bulk glassy alloys in as-cast bulk and melt-spun ribbon forms. A large supercooled liquid region over 50 K before crystallization was obtained in Fe-(Al, Ga)-(P, C, B, Si), Fe-(Cr, Mo, Nb)-(Al, Ga)-(P, C, B) and (Fe, Co, Ni)-Zr-M-B (M=Ti, Hf, V, Nb, Ta, Cr, Mo and W) systems and bulk glassy alloys were produced in a thickness range below 2 mm for the Fe-(Al, Ga)-(P, C, B, Si) system and 6 mm for the Fe-Co-(Zr, Nb, Ta)-(Mo, W)-B system by copper-mold casting. The ring-shaped glassy Fe-(Al, Ga)-(P, C, B, Si) alloys exhibit much better soft magnetic properties as compared with the ring-shaped alloy made from the melt-spun ribbon because of the formation of the unique domain structure. The good combination of high glass-forming ability and good soft magnetic properties indicates the possibility of future development as a new bulk glassy magnetic material

  2. Heat transport in bulk/nanoporous/bulk silicon devices

    Energy Technology Data Exchange (ETDEWEB)

    Criado-Sancho, M. [Departamento de Ciencias y Técnicas Físicoquimicas, Facultad de Ciencias, UNED, Senda del Rey 9, 20040 Madrid (Spain); Jou, D., E-mail: David.Jou@uab.cat [Departament de Física, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia (Spain); Institut d' Estudis Catalans, Carme 47, 08001 Barcelona, Catalonia (Spain)

    2013-02-04

    We study heat transport in bulk/nanoporous/bulk silicon devices; we show that, despite bulk/nanoporous devices may act as thermal rectifiers, the non-linear aspects of their joint thermal conductance are not strong enough to lead to a negative differential thermal resistance, necessary to allow bulk/nanoporous/bulk Si devices to act as thermal transistors. Furthermore, we explicitly study the effective thermal conductivity of the mentioned devices for several temperatures, geometries, porosities, and pore size.

  3. PROBLEMS OF BIOFOULING ON FISH–CAGE NETS IN AQUACULTURE

    Directory of Open Access Journals (Sweden)

    Merica Slišković

    2002-09-01

    Full Text Available Biofouling on fish–cage netting is a serious technical and economical problem to aquaculture worldwide. Compensation for the effects of biofouling must be included in cage system design and planning, as fouling can dramatically increase both weight and drag. Settlements of sessile plants and animals, with accumulation of the detritus diminish the size of mesh and can rapidly occlude mesh. Negative effect of smaller mesh size is changing in water flow trough the cages. Biofouling problems necessitating purchase of a second sets of nets or more, and frequent cleaning and changing of biofouling. Changing and cleaning frequency depend on many factors such as: location of cages (near the coast or off shore, productivity of that location, time of the year, time period in which the cages are placed on that location (cause of loading of phosphorus and nitrogen from the unconsumed food in the sediment. Net changing and cleaning procedures are labor and capital intensive. Process of the cleaning of the nets is inadequate, especially when there isnžt adequate equipment available as it is case in smaller aquaculture industry. Chemical control of biofouling e. g. use of antifoulants is questioningly cause of their possible negative effects on breeding species and environment.

  4. Effects of Furnished Cage Type on Behavior and Welfare of Laying Hens

    OpenAIRE

    LI, XIANG; Chen, Donghua; Li, Jianhong; Bao, Jun

    2015-01-01

    This study was conducted to compare the effects of layout of furniture (a perch, nest, and sandbox) in cages on behavior and welfare of hens. Two hundred and sixteen Hyline Brown laying hens were divided into five groups (treatments) with four replicates per group: small furnished cages (SFC), medium furnished cages type I (MFC-I), medium furnished cages type II (MFC-II), and medium furnished cages type III (MFC-III) and conventional cages (CC). The experiment started at 18 week of age and fi...

  5. Hexaphosphapentaprismane: a new gateway to organophosphorus cage compound chemistry.

    Science.gov (United States)

    al-Ktaifani, Mahmoud M; Bauer, Walter; Bergsträsser, Uwe; Breit, Bernhard; Francis, Matthew D; Heinemann, Frank W; Hitchcock, Peter B; Mack, Andreas; Nixon, John F; Pritzkow, Hans; Regitz, Manfred; Zeller, Matthias; Zenneck, Ulrich

    2002-06-01

    Several independent synthetic routes are described leading to the formation of a novel unsaturated tetracyclic phosphorus carbon cage compound tBu4C4P6 (1), which undergoes a light-induced valence isomerization to produce the first hexaphosphapentaprismane cage tBu4C4P6 (2). A second unsaturated isomer tBu4C4P6 (9) of 1 and the bis-[W(CO)5] complex 13 of 1 are stable towards similar isomerization reactions. Another starting material for the synthesis of the hexaphosphapentaprismane cage tBu4C4P6 (2) is the trimeric mercury complex [(tBu4C4P6)Hg]3 (11), which undergoes elimination of mercury to afford the title compound 2. Single-crystal X-ray structural determinations have been carried out on compounds 1, 2, 9, 11, and 13. PMID:12180342

  6. Encapsulation of cobalt nanoparticles in cross-linked-polymer cages

    Energy Technology Data Exchange (ETDEWEB)

    Hatamie, Shadie [Department of Electronic-Science, Fergusson College, Pune 411 004 (India); Dhole, S.D. [Department of Physics, University of Pune, Pune 411 007 (India); Ding, J. [Department of Materials Science and Engineering, National University of Singapore, 7, Engineering Drive 1, Singapore 117574 (Singapore); Kale, S.N. [Department of Electronic-Science, Fergusson College, Pune 411 004 (India)], E-mail: sangeetakale2004@gmail.com

    2009-07-15

    Nanoparticles embedded in polymeric cages give rise to interesting applications ranging from nanocatalysis to drug-delivery systems. In this context, we report on synthesis of cobalt (Co) nanoparticles trapped in polyvinyl alcohol (PVA) matrix to yield self-supporting magnetic films in PVA slime. A 20 nm, Co formed in FCC geometry encapsulated with a weak citrate coat when caged in PVA matrix exhibited persistence of magnetism and good radio-frequency response. Cross-linking of PVA chains to form cage-like structures to arrest Co nanoparticles therein, is believed to be the reason for oxide-free nature of Co, promising applications in biomedicine as well as in radio-frequency shielding.

  7. Mice Do Not Habituate to Metabolism Cage Housing

    DEFF Research Database (Denmark)

    Kalliokoski, Otto; Jacobsen, Kirsten Rosenmaj; Darusman, Huda Shalahudin;

    2013-01-01

    abnormality were monitored. Forced swim tests were conducted to determine whether the animals experienced behavioral despair and the serotonergic integrity was tested using an 8-OH-DPAT challenge. The metabolism cage housed mice excreted approximately tenfold higher amounts of corticosterone metabolites in...... in the present setup. In conclusion, the mice were found not to acclimatize to the metabolism cages whereby concern for animal welfare would dictate that mice should be housed in this way for as short periods as possible. The elevated degree of HPA axis activity, oxidative stress, and increased......The metabolism cage is a barren, non-enriched, environment, combining a number of recognized environmental stressors. We investigated the ability of male BALB/c mice to acclimatize to this form of housing. For three weeks markers of acute and oxidative stress, as well as clinical signs of...

  8. Bulk materials handling review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-02-15

    The paper provides details of some of the most important coal handling projects and technologies worldwide. It describes development by Aubema Crushing Technology GmbH, Bedeschi, Cimbria Moduflex, DBT, Dynamic Air Conveying Systems, E & F Services, InBulk Technologies, Nord-Sen Metal Industries Ltd., Pebco Inc, Primasonics International Ltd., R.J.S. Silo Clean (International) Ltd., Takraf GmbH, and The ACT Group. 17 photos.

  9. A Post-Functionalizable Iso-Polyoxotitanate Cage Cluster.

    Science.gov (United States)

    Hou, Jie; Hu, Junyi; Sun, Qing; Zhang, Guanyun; Tung, Chen-Ho; Wang, Yifeng

    2016-07-18

    During solvothermal alcoholysis of a mixture of TiI4 and Ti(O(i)Pr)4, a {I@Ti22} cage cluster encapsulating an OH and iodide guests is crystallized. The {I@Ti22} host-guest cluster surface is postfunctionalizable with catecholate and carboxylate ligands. The synthetic details, structural characterization, spectroscopic properties of the obtained cages clusters are provided. The present study provides candidates for modeling ligand exchange and electron-hole transfer at the titanate nanoparticle surface, and meanwhile offers new opportunities for understanding the TiO2 nanocrystalline formation in solvothermal processes. PMID:27351728

  10. Laboratory animal welfare: cage enrichment and mouse behaviour.

    Science.gov (United States)

    Wolfer, David P; Litvin, Oxana; Morf, Samuel; Nitsch, Roger M; Lipp, Hans-Peter; Würbel, Hanno

    2004-12-16

    Mice housed in standard cages show impaired brain development, abnormal repetitive behaviours (stereotypies) and an anxious behavioural profile, all of which can be lessened by making the cage environment more stimulating. But concerns have been raised that enriched housing might disrupt standardization and so affect the precision and reproducibility of behavioural-test results (for example, see ref. 4). Here we show that environmental enrichment increases neither individual variability in behavioural tests nor the risk of obtaining conflicting data in replicate studies. Our findings indicate that the housing conditions of laboratory mice can be markedly improved without affecting the standardization of results. PMID:15602544

  11. Equivalence Between Squirrel Cage and Sheet Rotor Induction Motor

    Science.gov (United States)

    Dwivedi, Ankita; Singh, S. K.; Srivastava, R. K.

    2016-06-01

    Due to topological changes in dual stator induction motor and high cost of its fabrication, it is convenient to replace the squirrel cage rotor with a composite sheet rotor. For an experimental machine, the inner and outer stator stampings are normally available whereas the procurement of rotor stampings is quite cumbersome and is not always cost effective. In this paper, the equivalence between sheet/solid rotor induction motor and squirrel cage induction motor has been investigated using layer theory of electrical machines, so as to enable one to utilize sheet/solid rotor in dual port experimental machines.

  12. Sex effect in mutual olfactory relationships of individually caged rabbits

    OpenAIRE

    Alessandro Finzi; Paolo Negretti; Giovanna Bianconi; Pedro González-Redondo

    2015-01-01

    To assess the sex influence on sniffing behavior of rabbits, sets of three rabbits each were located for seven days in contiguous cages divided by a metal wall with holes that prevented the neighboring rabbits to see each other. A buck was located in the central cage, with a doe at each side. Rabbit behavior was video recorded to observe animals sniffing with the muzzle near the wall. The bucks displayed an olfactory preference towards one of the two does, which decreased in few days. The sig...

  13. Reproductive performance of mice in disposable and standard individually ventilated cages.

    Science.gov (United States)

    Ferguson, Danielle R; Bailey, Michele M

    2013-01-01

    This study assessed the reproductive performance of mice housed in 2 types of individually ventilated caging systems. Breeding pairs from 48 female and 24 male mice of 3 established transgenic mouse breeding colonies were placed in either a standard or disposable ventilated caging system. For 3 breeding cycles, the number of pups born, pup survival rate to weaning, time interval between litters, and pup weights were monitored for each breeding pair. Disposable and standard cages were maintained in the same location during breeding. Environmental parameters included intracage temperature, humidity, and ammonia and carbon dioxide levels and room light intensity and sound. Overall, 776 offspring were produced. Breeding performance did not differ significantly between the 2 cage types. By 11 wk of age, the weights of pups from both cage types were equivalent. The intracage temperature was 1.1 °F warmer and light intensity at the site of the nest was 34 lx dimmer in disposable cages than in standard caging. The difference in lighting likely was due to nest location; the nests in the disposable cages were at the back of the cages and away from the anterior air supply, whereas in standard caging, nests were at the front of the cages, with the air supply at the rear. Under these husbandry conditions, mice housed in disposable caging systems have comparable breeding performance to those housed in standard individually ventilated cages. PMID:23849403

  14. Play Caging Benefits the Behavior of Singly Housed Laboratory Rhesus Macaques (Macaca mulatta)

    OpenAIRE

    Griffis, Caroline M; Martin, Allison L; Perlman, Jaine E; Bloomsmith, Mollie A

    2013-01-01

    This study addresses a recommendation in The Guide for the Care and Use of Laboratory Animals to provide singly housed nonhuman primates with intermittent access to large, enriched (play) caging. Research on the potential benefits of this type of caging is limited. The present study examines the effects of play caging on behavior, activity, and enrichment use. Singly housed, adult male, rhesus macaques (n = 10) underwent a baseline phase in their home cages, a 2-wk treatment phase with housin...

  15. Rearing Laying Hens in Aviaries Reduces Fearfulness following Transfer to Furnished Cages

    OpenAIRE

    Brantsæter, Margrethe; Tahamtani, Fernanda M.; Moe, Randi O; Hansen, Tone B.; Orritt, Rachel; Nicol, Christine; Janczak, Andrew M.

    2016-01-01

    Appropriate rearing is essential for ensuring the welfare and productivity of laying hens. Early experience has the potential to affect the development of fearfulness. This study tested whether rearing in aviaries, as opposed to cages, reduces the fearfulness of laying hens after transfer to furnished cages. Fear responses were recorded as avoidance of a novel object in the home cage. Lohmann Selected Leghorns were reared in an aviary system or conventional rearing cages and then transported ...

  16. Caged polyprenylated xanthones from the resin of Garcinia hanburyi.

    Science.gov (United States)

    Chen, Yu; He, Shiwen; Tang, Chu; Li, Jun; Yang, Guangzhong

    2016-03-01

    Five new caged polyprenylated xanthones (1a, 2a, 3, 10a and 10b), and 12 known related compounds were isolated from the resin of Garcinia hanburyi. Their structures were elucidated by detailed spectroscopic analyses and their α-glucosidase inhibitory activities were investigated in vitro. Most of xanthones showed modest inhibitory activity against α-glucosidase. PMID:26688377

  17. Pathogen Prevalence From Traditional Cage and Free Range Production

    Science.gov (United States)

    Overview: A study was conducted to determine if differences in pathogen prevalence occurred between a sister flock of conventional cage and free range laying hens. Both environmental and egg microbiology was monitored throughout 20 – 79 weeks of age. Salmonella, Campylobacter, and Listeria preval...

  18. Environmental Impact of Cage Culture on Poondi Reservoir, Tamil Nadu

    Directory of Open Access Journals (Sweden)

    P. Anusuya Devi

    2015-12-01

    Full Text Available The present investigation was carried out in Poondi reservoir, Tamil Nadu, for a period of 8 months from September, 2014 to April, 2015 where the cage culture has been already initiated by the state fisheries department. The water and sediment samples were collected from the reservoir at point and non- point sources of the cage culture units and were analyzed for their physico-chemical parameters. The total microbial load, E. coli and feacal streptococci population were also assessed from the reservoir. During the study period, pH, sulphate, nitrate and BOD values were found within the permissible range for drinking water quality. The alkalinity values were found optimum in the reservoir water. The sediment characteristics such as pH, electrical conductivity, total organic carbon and available phosphorus values were also found to be within the standard limit. The optimum water and sediment quality characteristics and the absence of E. coli and feacal streptococci observed in the cage culture unit clearly showed that the small cage farming in the reservoir does not have major environmental impacts on the water and sediment quality.

  19. Sex effect in mutual olfactory relationships of individually caged rabbits

    Directory of Open Access Journals (Sweden)

    Alessandro Finzi

    2015-12-01

    Full Text Available To assess the sex influence on sniffing behavior of rabbits, sets of three rabbits each were located for seven days in contiguous cages divided by a metal wall with holes that prevented the neighboring rabbits to see each other. A buck was located in the central cage, with a doe at each side. Rabbit behavior was video recorded to observe animals sniffing with the muzzle near the wall. The bucks displayed an olfactory preference towards one of the two does, which decreased in few days. The significance was p  0.05. The interest of bucks towards the does was also characterized by a frenetic scratching of the separation wall, contemporary with intense sniffing, displayed only for the first 35 min of the first day. The sniffing behavior of does at the central cage housing the male was not so marked as in bucks, and it progressively changed across the trial (p < 0.01. In conclusion, rabbits establish a transitory sex-oriented olfactory relationship with the conspecifics housed in contiguous cages, which looks no longer necessary once the rabbits have recognized each other.

  20. EFFECTS OF CAGING DENSITY ON PITUITARY AND TESTICLE RELATED RESPONSES

    Science.gov (United States)

    Effects of caging density on pituitary and testicle related responses A significant negative correlation between the incidence of testicular interstitial cell tumors (ICT) and of pituitary tumors (PT) in control male F344 rats is reported associated with the number of ani...

  1. Assessment of the Usability of the Workbench Faraday Cage Method

    DEFF Research Database (Denmark)

    Sørensen, Morten; Franek, Ondrej; Christensen, Søren K.; Pedersen, Gert Frølund; Ebert, Hans

    The workbench Faraday Cage method (WBFC) is a time efficient module pre-compliance test regarding radiated emission. This work investigates the method’s usability and credibility and concludes that for this particular case the WBFC perform a tolerable compliance test for frequencies below 360 MHz...

  2. Photoregulation of protein plasmid expression in vitro and in vivo using BHQ caging group

    Institute of Scientific and Technical Information of China (English)

    Zhi Ping Zhang; Yi Ming Li; Xiao Yun Chen; Qing Xiang Guo

    2011-01-01

    Green fluorescent protein (GFP) plasmid was caged by 8-bromo-7-hydroxyquinolinyl chromophore (BHQ) for controlling its expression with exact spatiotemporal resolution. In vitro and in vivo experiments clearly verified that, comparing with Bhc caging, the expression level of caged GFP plasmid was dramatically decreased and then efficiently restored after subsequent photolysis.

  3. Social communication in mice--are there optimal cage conditions?

    Directory of Open Access Journals (Sweden)

    Allain-Thibeault Ferhat

    Full Text Available Social communication is heavily affected in patients with neuropsychiatric disorders. Accordingly, mouse models designed to study the mechanisms leading to these disorders are tested for this phenotypic trait. Test conditions vary between different models, and the effect of these test conditions on the quantity and quality of social interactions and ultrasonic communication is unknown. The present study examines to which extent the habituation time to the test cage as well as the shape/size of the cage influence social communication in freely interacting mice. We tested 8 pairs of male mice in free dyadic social interactions, with two habituation times (20 min and 30 min and three cage formats (rectangle, round, square. We tested the effect of these conditions on the different types of social contacts, approach-escape sequences, follow behavior, and the time each animal spent in the vision field of the other one, as well as on the emission of ultrasonic vocalizations and their contexts of emission. We provide for the first time an integrated analysis of the social interaction behavior and ultrasonic vocalizations. Surprisingly, we did not highlight any significant effect of habituation time and cage shape/size on the behavioral events examined. There was only a slight increase of social interactions with the longer habituation time in the round cage. Remarkably, we also showed that vocalizations were emitted during specific behavioral sequences especially during close contact or approach behaviors. The present study provides a protocol reliably eliciting social contacts and ultrasonic vocalizations in adult male mice. This protocol is therefore well adapted for standardized investigation of social interactions in mouse models of neuropsychiatric disorders.

  4. Cage Versus Noncage Laying-Hen Housings: Worker Respiratory Health.

    Science.gov (United States)

    Mitchell, Diane; Arteaga, Veronica; Armitage, Tracey; Mitloehner, Frank; Tancredi, Daniel; Kenyon, Nicholas; Schenker, Marc

    2015-01-01

    The objective of this study was to compare respiratory health of poultry workers in conventional cage, enriched cage and aviary layer housing on a single commercial facility, motivated by changing requirements for humane housing of hens. Three workers were randomly assigned daily, one to each of conventional cage, enriched cage, and aviary housing in a crossover repeated-measures design for three observation periods (for a total of 123 worker-days, eight different workers). Workers' exposure to particles were assessed (Arteaga et al. J Agromedicine. 2015;20:this issue) and spirometry, exhaled nitric oxide, respiratory symptoms, and questionnaires were conducted pre- and post-shift. Personal exposures to particles and endotoxin were significantly higher in the aviary than the other housings (Arteaga et al., 2015). The use of respiratory protection was high; the median usage was 70% of the shift. Mixed-effects multivariate regression models of respiratory cross-shift changes were marginally significant, but the aviary system consistently posted the highest decrements for forced expiratory volume in 1 and 6 seconds (FEV1 and FEV6) compared with the enriched or conventional housing. The adjusted mean difference in FEV1 aviary - enriched cage housing was -47 mL/s, 95% confidence interval (CI): (-99 to 4.9), P = .07. Similarly, for FEV6, aviary - conventional housing adjusted mean difference was -52.9 mL/6 s, 95% CI: (-108 to 2.4), P = .06. Workers adopting greater than median use of respiratory protection were less likely to exhibit negative cross-shift pulmonary function changes. Although aviary housing exposed workers to significantly higher respiratory exposures, cross-shift pulmonary function changes did not differ significantly between houses. Higher levels of mask use were protective; poultry workers should wear respiratory protection as appropriate to avoid health decrements. PMID:26237715

  5. Complexation and aggregation of a surfactant cage molecule

    International Nuclear Information System (INIS)

    For applications in selective extraction chemistry, new surfactant cage molecules have been developed and their micellar aqueous solutions studied. With the objective of separating the surfactant properties from the complexing ones, the molecules have been designed with a di-block structure. They have been synthesized by grafting one (or more) surfactant unit to an aza crown macrocycle which is able to selectively complex cations. We have changed the number of linked surfactant (1 or 2) on the aza type cage. The complexing properties of those surfactant cage molecules with Na+ and K+ ions have been shown by mass-spectroscopy. The shape and aggregation number of the micelles are determined by fitting a molecular constrained model of the small angle X-ray and neutron scattering data simultaneously. The surfactant unit displays ellipsoidal to cylindrical micelles and bilayers while increasing the alkyl chain length. On the other hand, the surfactant cage molecules form ellipsoidal micelles whose structure is quite independent of the charge of the molecule. The structure is mostly controlled by the nature and the number of linked surfactants via their steric hindrance added to the volume of the macrocycle. In the last part of this work, we have rescaled a ionic flotation apparatus to dimensions suitable with a small quantity of available product. The surfactant is foaming in the flotation column. With this technic, we can study die adsorption equilibrium at the air/water interface. It is either the adsorption of the counter-ions of a ionic surfactant or the complexation of a cation with a macrocycle ligand at the interface. We have applied this method to a surfactant cage molecule in order to evaluate its extraction properties. (author)

  6. Wormholes in Bulk Viscous Cosmology

    OpenAIRE

    Jamil, Mubasher

    2008-01-01

    We investigate the effects of the accretion of phantom energy with non-zero bulk viscosity onto a Morris-Thorne wormhole. We have found that if the bulk viscosity is large then the mass of wormhole increases rapidly as compared to small or zero bulk viscosity.

  7. Multiplexed Analysis of Cage and Cage Free Chicken Egg Fatty Acids Using Stable Isotope Labeling and Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Richard G. Torde

    2013-12-01

    Full Text Available Binary stable isotope labeling couple with LC-ESI-MS has been used as a powerful non-targeted approach for the relative quantification of lipids, amino acids, and many other important metabolite classes. A multiplexed approach using three or more isotopic labeling reagents greatly reduces analytical run-time while maintaining excellent sensitivity and reproducibility. Three isotopic cholamine labeling reagents have been developed to take advantage of the pre-ionized character of cholamine, for ESI, and the ease by which stable isotopes can be incorporated into the cholamine structure. These three cholamine labeling reagents have been used to relatively quantify three fatty acid samples simultaneously. The quantification resulted in the observation of 12 fatty acids that had an average absolute error of 0.9% and an average coefficient of variation of 6.1%. Caged versus cage-free isotope labeling experiments showed that cage-free eggs have an increased level of omega-3 fatty acids as compared to caged eggs. This multiplexed fatty acid analysis provides an inexpensive and expedited tool for broad-based lipid profiling that will further aid discoveries in the mechanisms of fatty acid action in cells.

  8. Impaired fear extinction as displayed by serotonin transporter knockout rats housed in open cages is disrupted by IVC cage housing.

    Directory of Open Access Journals (Sweden)

    Ling Shan

    Full Text Available Anxiety disorders are influenced by both environmental and genetic factors. A well-known example for gene x environment interactions in psychiatry is the low activity (s allelic variant of the serotonin transporter (5-HTT promoter polymorphism (5-HTTLPR that in the context of stress increases risk for depression and post-traumatic stress disorder (PTSD. Previously, we observed robust anxiety-related phenotypes, such as an impairment in fear extinction, in 5-HTT knockout (5-HTT-/- versus wild-type (5-HTT+/+ rats housed in open cages. Recently, housing conditions were changed from open cages to individually ventilated cages (IVC, which are associated with a high ventilation fold and noise. This switch in housing conditions prompted an unplanned 5-HTT gene x environment interaction study in our rats. The current study shows that lifetime stress by means of IVC cage housing abolished genotype differences in fear extinction between 5-HTT-/- and 5-HTT+/+ rats. Although this effect was not attributed specifically to either the 5-HTT+/+ or the 5-HTT-/- genotype, the findings are in agreement with the modulatory role of serotonin in the processing of environmental stimuli. Our findings also underline the possibility that housing conditions confound the interpretation of anxiety-related behaviours in rodents.

  9. Effects of cage density, sanitation frequency, and bedding type on animal wellbeing and health and cage environment in mice and rats.

    Science.gov (United States)

    Horn, Mandy J; Hudson, Shanice V; Bostrom, Linda A; Cooper, Dale M

    2012-11-01

    The objective of the current study was to evaluate the effects of cage density, sanitation frequency, and bedding type on animal growth and welfare. At weaning, Sprague-Dawley rats and C57BL/6 mice were allocated to treatment groups according to sex, bedding type (shredded aspen, cellulose, or a 50:50 mixture), and cage density and sanitation frequency (inhouse cage density standards and sanitation procedures measured against Guide recommendations) for an 8-wk period. Body weight, feed disappearance, cage ammonia, ATP concentrations, behavior, morbidity, and mortality were assessed weekly; fecal corticosterone, microbiology, and lung histopathology (rats only) were evaluated at the culmination of the trial. In both rats and mice, parameters indicative of animal health and welfare were not significantly affected by cage density and sanitation frequency or bedding type. Occasional effects of feed disappearance and cage ammonia concentrations due to density and sanitation guidelines were noted in rat cages, and bedding type affected cage ammonia and ATP concentrations. Periodic spikes of cage ammonia and ATP concentrations were recorded in mouse cages maintained according to inhouse compared with Guide standards and in cages containing aspen compared with cellulose or aspen-cellulose mixed bedding. Ongoing studies and historical data support the finding that deviations or exceptions from the cage density and sanitation frequency standards set forth in the Guide do not negatively affect animal health, welfare, or production parameters at our institution. These parameters appear to be credible measures of animal health and wellbeing and may be useful for evaluating performance standards for animal husbandry. PMID:23294884

  10. Effects of Cage Density, Sanitation Frequency, and Bedding Type on Animal Wellbeing and Health and Cage Environment in Mice and Rats

    OpenAIRE

    Horn, Mandy J; Hudson, Shanice V.; Bostrom, Linda A; Cooper, Dale M

    2012-01-01

    The objective of the current study was to evaluate the effects of cage density, sanitation frequency, and bedding type on animal growth and welfare. At weaning, Sprague–Dawley rats and C57BL/6 mice were allocated to treatment groups according to sex, bedding type (shredded aspen, cellulose, or a 50:50 mixture), and cage density and sanitation frequency (inhouse cage density standards and sanitation procedures measured against Guide recommendations) for an 8-wk period. Body weight, feed disapp...

  11. Creating bulk nanocrystalline metal.

    Energy Technology Data Exchange (ETDEWEB)

    Fredenburg, D. Anthony (Georgia Institute of Technology, Atlanta, GA); Saldana, Christopher J. (Purdue University, West Lafayette, IN); Gill, David D.; Hall, Aaron Christopher; Roemer, Timothy John (Ktech Corporation, Albuquerque, NM); Vogler, Tracy John; Yang, Pin

    2008-10-01

    Nanocrystalline and nanostructured materials offer unique microstructure-dependent properties that are superior to coarse-grained materials. These materials have been shown to have very high hardness, strength, and wear resistance. However, most current methods of producing nanostructured materials in weapons-relevant materials create powdered metal that must be consolidated into bulk form to be useful. Conventional consolidation methods are not appropriate due to the need to maintain the nanocrystalline structure. This research investigated new ways of creating nanocrystalline material, new methods of consolidating nanocrystalline material, and an analysis of these different methods of creation and consolidation to evaluate their applicability to mesoscale weapons applications where part features are often under 100 {micro}m wide and the material's microstructure must be very small to give homogeneous properties across the feature.

  12. Explosive bulk charge

    Science.gov (United States)

    Miller, Jacob Lee

    2015-04-21

    An explosive bulk charge, including: a first contact surface configured to be selectively disposed substantially adjacent to a structure or material; a second end surface configured to selectively receive a detonator; and a curvilinear side surface joining the first contact surface and the second end surface. The first contact surface, the second end surface, and the curvilinear side surface form a bi-truncated hemispherical structure. The first contact surface, the second end surface, and the curvilinear side surface are formed from an explosive material. Optionally, the first contact surface and the second end surface each have a substantially circular shape. Optionally, the first contact surface and the second end surface consist of planar structures that are aligned substantially parallel or slightly tilted with respect to one another. The curvilinear side surface has one of a smooth curved geometry, an elliptical geometry, and a parabolic geometry.

  13. The Incredible Bulk

    CERN Document Server

    Fukushima, Keita; Kumar, Jason; Sandick, Pearl; Yamamoto, Takahiro

    2014-01-01

    Recent experimental results from the LHC have placed strong constraints on the masses of colored superpartners. The MSSM parameter space is also constrained by the measurement of the Higgs boson mass, and the requirement that the relic density of lightest neutralinos be consistent with observations. Although large regions of the MSSM parameter space can be excluded by these combined bounds, leptophilic versions of the MSSM can survive these constraints. In this paper we consider a scenario in which the requirements of minimal flavor violation, vanishing $CP$-violation, and mass universality are relaxed, specifically focusing on scenarios with light sleptons. We find a large region of parameter space, analogous to the original bulk region, for which the lightest neutralino is a thermal relic with an abundance consistent with that of dark matter. We find that these leptophilic models are constrained by measurements of the magnetic and electric dipole moments of the electron and muon, and that these models have ...

  14. Bulk muscles, loose cables.

    Science.gov (United States)

    Liyanage, Chamari R D G; Kodali, Venkata

    2014-01-01

    The accessibility and usage of body building supplements is on the rise with stronger internet marketing strategies by the industry. The dangers posed by the ingredients in them are underestimated. A healthy young man came to the emergency room with palpitations and feeling unwell. Initial history and clinical examination were non-contributory to find the cause. ECG showed atrial fibrillation. A detailed history for any over the counter or herbal medicine use confirmed that he was taking supplements to bulk muscle. One of the components in these supplements is yohimbine; the onset of symptoms coincided with the ingestion of this product and the patient is symptom free after stopping it. This report highlights the dangers to the public of consuming over the counter products with unknown ingredients and the consequential detrimental impact on health. PMID:25326558

  15. Effects of single caging and cage size on behavior and stress level of domestic neutered cats housed in an animal shelter.

    Science.gov (United States)

    Uetake, Katsuji; Goto, Akihiro; Koyama, Rumi; Kikuchi, Rieko; Tanaka, Toshio

    2013-03-01

    Cats need a minimum amount of space even in animal shelters. In this study the effects of single caging and cage size on the behavior and stress level of domestic cats were investigated. Six neutered cats (2-15 years old) that had been housed in a group for at least 7 months were moved to three kinds of single cages (small, medium and large) by rotation on a Latin square design. They experienced each cage size for 6 days. Cats could use vertical dimensions when housed in a group room and the large cage. Behavioral observation was conducted for 3 h in the evening, and stress levels were assessed by urine cortisol-to-creatinine ratios. The amounts (estimated proportions) of time spent in locomotion and social/solitary play were lower even in large cages than in group housing (both P < 0.05). Conversely, the amount of time spent resting tended to increase when housed singly (P = 0.104). The urine cortisol-to-creatinine ratios of singly housed cats tended to be higher than that of group-housed cats (P = 0.086). The results indicate that cats become less active when they are housed singly in cages regardless of the cage size. Cats seem to feel no undue stress even in small cages if the stay is short. PMID:23480709

  16. Lanthanides caged by the organic chelates; structural properties

    Science.gov (United States)

    Smentek, Lidia

    2011-04-01

    The structure, in particular symmetry, geometry and morphology of organic chelates coordinated with the lanthanide ions are analyzed in the present review. This is the first part of a complete presentation of a theoretical description of the properties of systems, which are widely used in technology, but most of all, in molecular biology and medicine. The discussion is focused on the symmetry and geometry of the cages, since these features play a dominant role in the spectroscopic activity of the lanthanides caged by organic chelates. At the same time, the spectroscopic properties require more formal presentation in the language of Racah algebra, and deserve a separate analysis. In addition to the parent systems of DOTA, DOTP, EDTMP and CDTMP presented here, their modifications by various antennas are analyzed. The conclusions that have a strong impact upon the theory of the energy transfer and the sensitized luminescence of these systems are based on the results of numerical density functional theory calculations.

  17. Jamming vs Caging in Three Dimensional Jamming Percolation

    Science.gov (United States)

    Shokef, Yair; Segall, Nimrod; Teomy, Eial

    We study a three-dimensional kinetically-constrained lattice-gas model, in which the ability of a particle to move depends on the occupation of neighboring sites in an orientational manner. The kinetic rules are constructed such that chains of permanently-frozen particles reach an infinite length at the critical density of directed percolation. Thus at this critical density the system undergoes a jamming transition, above which there is a finite fraction of jammed particles. We demonstrate that the three-dimensional mesh-like structure of the one-dimensional jammed chains enables the free particles to propagate through the holes in this mesh. This diffusive motion is terminated at a second critical density above which all particles are caged. The largest and second largest clusters of dynamically-connected sites exhibit singularities at both densities. Thus our model assists in separating between the two distinct phenomena of jamming and caging.

  18. Cages and Anomalous Diffusion in Vibrated Dense Granular Media

    Science.gov (United States)

    Scalliet, Camille; Gnoli, Andrea; Puglisi, Andrea; Vulpiani, Angelo

    2015-05-01

    A vertically shaken granular medium hosts a blade rotating around a fixed vertical axis, which acts as a mesorheological probe. At high densities, independently of the shaking intensity, the blade's dynamics shows strong caging effects, marked by transient subdiffusion and a maximum in the velocity power density spectrum, at a resonant frequency ˜10 Hz . Interpreting the data through a diffusing harmonic cage model allows us to retrieve the elastic constant of the granular medium and its collective diffusion coefficient. For high frequencies f , a tail ˜1 /f in the velocity power density spectrum reveals nontrivial correlations in the intracage microdynamics. At very long times (larger than 10 s), a superdiffusive behavior emerges, ballistic in the most extreme cases. Consistently, the distribution of slow velocity inversion times τ displays a power-law decay, likely due to persistent collective fluctuations of the host medium.

  19. Cages and anomalous diffusion in vibrated dense granular media.

    Science.gov (United States)

    Scalliet, Camille; Gnoli, Andrea; Puglisi, Andrea; Vulpiani, Angelo

    2015-05-15

    A vertically shaken granular medium hosts a blade rotating around a fixed vertical axis, which acts as a mesorheological probe. At high densities, independently of the shaking intensity, the blade's dynamics shows strong caging effects, marked by transient subdiffusion and a maximum in the velocity power density spectrum, at a resonant frequency ~10 Hz. Interpreting the data through a diffusing harmonic cage model allows us to retrieve the elastic constant of the granular medium and its collective diffusion coefficient. For high frequencies f, a tail ~1/f in the velocity power density spectrum reveals nontrivial correlations in the intracage microdynamics. At very long times (larger than 10 s), a superdiffusive behavior emerges, ballistic in the most extreme cases. Consistently, the distribution of slow velocity inversion times τ displays a power-law decay, likely due to persistent collective fluctuations of the host medium. PMID:26024199

  20. Rotational Brownian Dynamics simulations of clathrin cage formation

    International Nuclear Information System (INIS)

    The self-assembly of nearly rigid proteins into ordered aggregates is well suited for modeling by the patchy particle approach. Patchy particles are traditionally simulated using Monte Carlo methods, to study the phase diagram, while Brownian Dynamics simulations would reveal insights into the assembly dynamics. However, Brownian Dynamics of rotating anisotropic particles gives rise to a number of complications not encountered in translational Brownian Dynamics. We thoroughly test the Rotational Brownian Dynamics scheme proposed by Naess and Elsgaeter [Macromol. Theory Simul. 13, 419 (2004); Naess and Elsgaeter Macromol. Theory Simul. 14, 300 (2005)], confirming its validity. We then apply the algorithm to simulate a patchy particle model of clathrin, a three-legged protein involved in vesicle production from lipid membranes during endocytosis. Using this algorithm we recover time scales for cage assembly comparable to those from experiments. We also briefly discuss the undulatory dynamics of the polyhedral cage

  1. Environmental Enrichment Reduces Signs of Boredom in Caged Mink

    OpenAIRE

    Meagher, Rebecca K.; Mason, Georgia J

    2012-01-01

    Animals housed in impoverished cages are often labelled ‘bored’. They have also been called ‘apathetic’ or ‘depressed’, particularly when profoundly inactive. However, these terms are rarely operationally defined and validated. As a negative state caused by under-stimulation, boredom should increase interest in stimuli of all kinds. Apathy (lack of interest), by contrast, should manifest as decreased interest in all stimuli, while anhedonia (loss of pleasure, a depressive symptom) should spec...

  2. Inflation from bulk viscosity

    CERN Document Server

    Bamba, Kazuharu

    2015-01-01

    We explore the perfect fluid description of the inflationary universe. In particular, we investigate a fluid model with the bulk-viscosity term. We find that the three observables of inflationary cosmology: the spectral index of the curvature perturbations, the tensor-to-scalar ratio of the density perturbations, and the running of the spectral index, can be consistent with the recent Planck results. We also reconstruct the explicit equation of state (EoS) of the viscous fluid from the spectral index of the curvature perturbations compatible with the Planck analysis. In the reconstructed models of the viscous fluid, the tensor-to-scalar ratio of the density perturbations can satisfy the constraints obtained from the Planck satellite. The running of the spectral index can explain the Planck data. In addition, it is demonstrated that in the reconstructed models of the viscous fluid, the graceful exit from inflation can be realized. Furthermore, we show that the singular inflation can occur in the viscous fluid ...

  3. Bulk-Fill Resin Composites

    DEFF Research Database (Denmark)

    Benetti, Ana Raquel; Havndrup-Pedersen, Cæcilie; Honoré, Daniel;

    2015-01-01

    restorative procedure. The aim of this study, therefore, was to compare the depth of cure, polymerization contraction, and gap formation in bulk-fill resin composites with those of a conventional resin composite. To achieve this, the depth of cure was assessed in accordance with the International Organization...... for Standardization 4049 standard, and the polymerization contraction was determined using the bonded-disc method. The gap formation was measured at the dentin margin of Class II cavities. Five bulk-fill resin composites were investigated: two high-viscosity (Tetric EvoCeram Bulk Fill, SonicFill) and...... three low-viscosity (x-tra base, Venus Bulk Fill, SDR) materials. Compared with the conventional resin composite, the high-viscosity bulk-fill materials exhibited only a small increase (but significant for Tetric EvoCeram Bulk Fill) in depth of cure and polymerization contraction, whereas the low...

  4. Effect of Cage-Wash Temperature on the Removal of Infectious Agents from Caging and the Detection of Infectious Agents on the Filters of Animal Bedding-Disposal Cabinets by PCR Analysis

    OpenAIRE

    Compton, Susan R; Macy, James D

    2015-01-01

    Efficient, effective cage decontamination and the detection of infection are important to sustainable biosecurity within animal facilities. This study compared the efficacy of cage washing at 110 and 180 °F on preventing pathogen transmission. Soiled cages from mice infected with mouse parvovirus (MPV) and mouse hepatitis virus (MHV) were washed at 110 or 180 °F or were not washed. Sentinels from washed cages did not seroconvert to either virus, whereas sentinels in unwashed cages seroconvert...

  5. Energy saving work of frequency controlled induction cage machine

    International Nuclear Information System (INIS)

    Energy saving work, understood as lowering the supply voltage when load torque is much less than rated, is one way of reducing power losses in an induction cage machine working with a variable load. Reduction in power losses also affects the thermal properties of an induction machine because the energy saving work allows the temperature rise of the windings to decrease. Thanks to a lower temperature of the windings, the same load torque can be carried by a machine of less rated power. The ability of energy saving work to reduce the temperature of windings depends on the thermal properties of an induction machine, which are different in the case of a machine with foreign ventilation and its own ventilation. This paper deals with the thermal effect of energy saving work on a frequency controlled induction cage machine. A comparison of the properties of a machine with its own and outside ventilation is presented. The results of the investigations are shown for a 3 kW induction cage machine with the two previously mentioned ways of ventilation: one provided with a fan placed on a shaft and the other provided with a fan driven by an auxiliary motor

  6. Genotoxicity monitoring of freshwater environments using caged carp (Cyprinus carpio).

    Science.gov (United States)

    Klobucar, Göran I V; Stambuk, Anamaria; Pavlica, Mirjana; Sertić Perić, Mirela; Kutuzović Hackenberger, Branimir; Hylland, Ketil

    2010-01-01

    The present study deals with genotoxicity assessment of freshwaters using caged carp (Cyprinus carpio). Carps were transplanted from a fish-farm to three differently polluted sites in eastern Croatia. Two polluted sites were situated in the river Drava, downstream from the cities of Belisće and Osijek, while the reference site was in the Nature Park Kopacki rit, a preserved wetland area with limited anthropogenic influence. Exposure lasted for 3 weeks and was repeated for 3 years (2002-2004). DNA damage was assessed in erythrocytes of the exposed animals by the Comet assay and micronucleus test (MNT). In order to evaluate possible differences in stress responses to polluted water in situ and in aquaria a laboratory exposure was performed with water from the studied location in the second year of the study. Carp from the sites with high anthropogenic influence (Belisće and Osijek) had higher average DNA damage as expressed in both the MNT and Comet assay. Of the two, the Comet assay appeared to be more sensitive following both caging and aquaria exposures. The results from this study suggest that 3 weeks caging exposure of C. carpio may be a useful strategy to monitor for genotoxic agents in freshwater ecosystems. PMID:19626438

  7. Prevalence of Salmonella in flocks housed in enriched cages.

    Science.gov (United States)

    Zongo, P; Ducrot, A; Burie, J-B; Beaumont, C

    2015-04-01

    Salmonellosis is a foodborne disease of humans and animals caused by infection with Salmonella. The aim of this paper is to improve a deterministic model (DM) and an individual-based model (IBM) with reference to Salmonella propagation in flocks of laying hens taking into account variations in hens housed in the same cage and to compare both models. The spatio-temporal evolution, the basic reproduction number, R 0, and the speed of wave propagation were computed for both models. While in most cases the DM allows summary of all the features of the model in the formula for computation of R 0, slight differences between individuals or groups may be observed with the IBM that could not be expected from the DM, especially when initial environmental contamination is very low and some cages may get rid of bacteria. Both models suggest that the cage size plays a role on the risk and speed of propagation of the bacteria, which should be considered when designing new breeding systems. PMID:25084397

  8. Flow Field Characteristics of the Rotor Cage in Turbo Air Classifiers

    Institute of Scientific and Technical Information of China (English)

    GUO Lijie; LIU Jiaxiang; LIU Shengzhao

    2009-01-01

    The turbo air classifier is widely used powder classification equipment in a variety of fields. The flow field characteristics of the turbo air classifier are important basis for the improvement of the turbo air classifier's structural design. The flow field characteristics of the rotor cage in turbo air classifiers were investigated under different operating conditions by laser Doppler velocimeter(LDV), and a measure diminishing the axial velocity is proposed. The investigation results show that the tangential velocity of the air flow inside the rotor cage is different from the rotary speed of the rotor cage on the same measurement point due to the influences of both the negative pressure at the exit and the rotation of the rotor cage. The tangential velocity of the air flow likewise decreases as the radius decreases in the case of the rotor cage's low rotary speed. In contrast, the tangential velocity of the air flow increases as the radius decreases in the case of the rotor cage's high rotary speed. Meanwhile, the vortex inside the rotor cage is found to occur near the pressure side of the blade when the rotor cage's rotary speed is less than the tangential velocity of air flow. On the contrary, the vortex is found to occur near the blade suction side once the rotor cage's rotary speed is higher than the tangential velocity of air flow. Inside the rotor cage, the axial velocity could not be disregarded and is largely determined by the distances between the measurement point and the exit.

  9. Influence of 5 Different Caging Types and the Use of Cage-Changing Stations on Mouse Allergen Exposure

    OpenAIRE

    Feistenauer, Susan; Sander, Ingrid; Schmidt, Jörg; Zahradnik, Eva; Raulf, Monika; Brielmeier, Markus

    2014-01-01

    Animal allergens constitute a serious health risk in laboratory animal facilities. To assess possibilities for allergen reduction by technical and organizational measures, we studied personnel exposure to mouse urinary aeroallergens in an animal facility with a holding capacity of 30,000 cages. Short-term (2 h) and intermediate-term (12 h) stationary samples (n = 107) and short-term (2 h) personnel samples (n = 119) were collected on polytetrafluorethylene filters by using air pumps. Long-ter...

  10. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups

    Czech Academy of Sciences Publication Activity Database

    Palma-Cerda, F.; Auger, C.; Crawford, D.J.; Hodgson, A.C.C.; Reynolds, S.J.; Cowell, J.K.; Swift, K.A.D.; Cais, Ondřej; Vyklický ml., Ladislav; Corrie, J.E.T.; Ogden, D.

    2012-01-01

    Roč. 63, č. 4 (2012), s. 624-634. ISSN 0028-3908 R&D Projects: GA ČR(CZ) GA309/07/0271 Grant ostatní: EC(XE) LSHM-CT-2007-037765 Institutional research plan: CEZ:AV0Z50110509 Keywords : photolysis * glutamate receptors * caged neurotransmitters Subject RIV: ED - Physiology Impact factor: 4.114, year: 2012

  11. Effects of Furnished Cage Type on Behavior and Welfare of Laying Hens.

    Science.gov (United States)

    Li, Xiang; Chen, Donghua; Li, Jianhong; Bao, Jun

    2016-06-01

    This study was conducted to compare the effects of layout of furniture (a perch, nest, and sandbox) in cages on behavior and welfare of hens. Two hundred and sixteen Hyline Brown laying hens were divided into five groups (treatments) with four replicates per group: small furnished cages (SFC), medium furnished cages type I (MFC-I), medium furnished cages type II (MFC-II), and medium furnished cages type III (MFC-III) and conventional cages (CC). The experiment started at 18 week of age and finished at 52 week of age. Hens' behaviors were filmed during the following periods: 8:00 to 10:00; 13:00 to 14:00; 16:00 to 17:00 on three separate days and two hens from each cage were measured for welfare parameters at 50 wk of age. The results showed that feeding and laying of all hens showed no effect by cage type (p>0.05), and the hens in the furnished cages had significantly lower standing and higher walking than CC hens (phens between the furnished cages (p>0.05). The hens in MFC-I, -II, and -III showed a significant higher socializing behavior than SFC and CC (phens in SFC and the highest perching found for the hens in MFC-III. Overall, the hens in CC showed poorer welfare conditions than the furnished cages, in which the feather condition score, gait score and tonic immobility duration of the hens in CC was significantly higher than SFC, MFC-I, MFC-II, and MFC-III (phens. Overall, MFC-III cage design was better than SFC, MFC-I, and MFC-II cage designs. PMID:26954171

  12. Protein denaturation in wet nanoporous silica gels: effect of caging and crowding on the dynamics of GFPmut2

    International Nuclear Information System (INIS)

    Proteins encapsulated in wet, nanoporous silica gels usually maintain their structural and functional properties. However, excluded-volume effects and the perturbation of water structure inside the pores of the gel may influence the kinetics of conformational transitions and the thermodynamics of functionally relevant conformational states. We investigated the unfolding of a mutant of GFP, GFPmut2, in wet nanoporous gels. Protein molecules are individually caged in the pores of the gel, avoiding protein aggregation and reproducing some of the effects exerted by molecular crowding and confinement in the cellular environment. Encapsulation in silica gels results in the alteration of the equilibrium distribution of native conformations, so that at least two alternative substates of the protein, spectrally undistinguishable in bulk studies, are significantly populated in the absence of denaturant. The evidence of an altered conformational distribution upon caging indicates that studies in dilute solution can miss functionally relevant structural and dynamic properties, highlighting the importance to carry out experiments under conditions that mimic the intracellular milieu

  13. Clinical outcomes of two types of cages used in transforaminal lumbar interbody fusion for the treatment of degenerative lumbar diseases: n-HA/PA66 cages versus PEEK cages.

    Science.gov (United States)

    Deng, Qian-Xing; Ou, Yun-Sheng; Zhu, Yong; Zhao, Zeng-Hui; Liu, Bo; Huang, Qiu; Du, Xing; Jiang, Dian-Ming

    2016-06-01

    This study reports the clinical effects of nano-hydroxyapatite/polyamide66 cages (n-HA/PA66 cages) and compares the clinical outcomes between n-HA/PA66 and polyetheretherketone cages (PEEK cages) for application in transforaminal lumbar interbody fusion (TLIF). A retrospective and case-control study involving 124 patients using n-HA/PA66 cages and 142 patients using PEEK cages was conducted. All patients underwent TLIF and had an average of 2-years of follow-up. The Oswestry Disability Index and Visual Analog Scale were selected to assess the pain of low back and leg, as well as neurological status. The intervertebral space height and segmental angle were also measured to estimate the radiological changes. At the 1-year and final follow-ups, the fusion and subsidence rates were evaluated. There was no significant difference between the two groups regarding clinical and radiological results. At the final follow-up, the bony fusion rate was 92.45 and 91.57 % for the n-HA/PA66 and PEEK groups, respectively, and the subsidence rate was 7.55 and 8.99 %, respectively. The study indicated that both n-HA/PA66 and PEEK cages could promote effective clinical and radiographic outcomes when used to treat degenerative lumbar diseases. The high fusion and low subsidence rates revealed that n-HA/PA66 cages could be an alternative ideal choice as the same to PEEK cages for lumbar reconstruction after TLIF. PMID:27091044

  14. Reproductive Performance of Mice in Disposable and Standard Individually Ventilated Cages

    OpenAIRE

    Ferguson, Danielle R; Bailey, Michele M

    2013-01-01

    This study assessed the reproductive performance of mice housed in 2 types of individually ventilated caging systems. Breeding pairs from 48 female and 24 male mice of 3 established transgenic mouse breeding colonies were placed in either a standard or disposable ventilated caging system. For 3 breeding cycles, the number of pups born, pup survival rate to weaning, time interval between litters, and pup weights were monitored for each breeding pair. Disposable and standard cages were maintain...

  15. Are assemblages of the fireworm Hermodice carunculata enhanced in sediments beneath offshore fish cages?

    Institute of Scientific and Technical Information of China (English)

    Rodrigo Riera; Oscar Prez; Myriam Rodrguez; Eva Ramos; scar Monterroso

    2014-01-01

    Abundances of the fireworm Hermodice carunculata were counted through a monitoring assessment study of fish cages in Barranco Hondo (NE Tenerife). Seven campaigns were conducted from November 2007 to June 2010 and temporal variations were found, as well as differences among sampling stations. The poly-chaete H. carunculata obtained its highest abundance in sediments beneath fish cages throughout the study period. Thus, the assemblages of this omnivorous species were favoured by the presence of fish cages.

  16. Healing properties of allograft from alendronate-treated animal in lumbar spine interbody cage fusion

    OpenAIRE

    Xue, Qingyun; Li, Haisheng; Zou, Xuenong; Bünger, Mathias; Egund, Niels; Lind, Martin; Christensen, Finn Bjarke; Bünger, Cody

    2004-01-01

    This study investigated the healing potential of allograft from bisphosphonate-treated animals in anterior lumbar spine interbody fusion. Three levels of anterior lumbar interbody fusion with Brantigan cages were performed in two groups of five landrace pigs. Empty Brantigan cages or cages filled with either autograft or allograft were located randomly at different levels. The allograft materials for the treatment group were taken from the pigs that had been fed with alendronate, 10 mg daily ...

  17. Animal Welfare and Food Safety Aspects of Confining Broiler Chickens to Cages

    OpenAIRE

    Sara Shields; Michael Greger

    2013-01-01

    Simple Summary In commercial chicken meat production, broiler chickens are usually kept on the floor in ware-house like buildings, but the use of cages is becoming more common. Confining chickens to cages is a welfare problem, as has been thoroughly demonstrated for laying hens used for egg production. Caged broiler chickens may suffer from poor bone strength due to lack of exercise, feather loss, and restriction of natural behavior. There are also potential food safety concerns associated wi...

  18. Individually Ventilated Cages Impose Cold Stress on Laboratory Mice: A Source of Systemic Experimental Variability

    OpenAIRE

    David, John M.; Knowles, Scott; Lamkin, Donald M.; Stout, David B.

    2013-01-01

    Individual ventilated cages (IVC) are increasing in popularity. Although mice avoid IVC in preference testing, they show no aversion when provided additional nesting material or the cage is not ventilated. Given the high ventilation rate in IVC, we developed 3 hypotheses: that mice housed in IVC experience more cold stress than do mice housed in static cages; that IVC-induced cold stress affects the results of experiments using mice; and that, when provided shelters, mice behaviorally thermor...

  19. Haematological and Biochemical Parameters during the Laying Period in Common Pheasant Hens Housed in Enhanced Cages

    OpenAIRE

    Petra Hrabčáková; Eva Voslářová; Iveta Bedáňová; Vladimíra Pištěková; Jan Chloupek; Vladimír Večerek

    2014-01-01

    The development of selected haematological and biochemical parameters during the laying period was monitored in common pheasant hens housed in an enhanced cage system. The cages were enhanced by the addition of two perches and a shelter formed by strips of cloth hanging in the corner of the cage. The results showed significant changes in the haematological and biochemical parameters monitored during egg laying. At the time when laying capacity approached a maximum, a decrease was observed (P ...

  20. Cage Change Influences Serum Corticosterone and Anxiety-Like Behaviors in the Mouse

    OpenAIRE

    Rasmussen, Skye; Miller, Melinda M.; Filipski, Sarah B.; Tolwani, Ravi J.

    2011-01-01

    Environmental variables and husbandry practices can influence physiology and alter behavior in mice. Our study evaluated the effects of cage change on serum corticosterone levels and anxiety-like behaviors in C57BL/6 male mice. We examined the effects of 3 different methods of performing cage transfer and of transferring mice to a clean or a dirty familiar cage microenvironment. The 3 different handling methods were forceps transfer, gentle transfer with gloved hands, and a passive transfer t...

  1. Progesterone After Estradiol Modulates Shuttle-Cage Escape by Facilitating Volition

    OpenAIRE

    Mayeaux, Darryl J.; Tandle, Sarah M.; Cilano, Sean M.; Fitzharris, Matthew J.

    2016-01-01

    In animal models of depression, depression is defined as performance on a learning task. That task is typically escaping a mild electric shock in a shuttle cage by moving from one side of the cage to the other. Ovarian hormones influence learning in other kinds of tasks, and these hormones are associated with depressive symptoms in humans. The role of these hormones in shuttle-cage escape learning, however, is less clear. This study manipulated estradiol and progesterone in ovariectomized fem...

  2. Stand-alone LLIF Lateral Cage Migration: A Case Report.

    Science.gov (United States)

    Towers, Wendy S; Kurtom, Khalid H

    2015-01-01

    Lateral approaches to the lumbar disc space have become popular in recent years with very few reported complications. We report on a rare case of a stand-alone cage migration. A 77-year-old female presented with a right L2-3 radiculopathy that was refractory to maximum medical management. This was secondary to foraminal compression at L2-3 and L3-4 due to degenerative disc disease and levoscoliosis, as well as Grade 1 spondylolisthesis at both levels. A left-sided approach lateral lumbar interbody fusion was performed at L2-3 and L3-4 using a lordotic polyetheretherketone (PEEK) graft (50 mm length x 18 mm width x 9 mm height) packed with demineralized bone matrix (DBM). A contralateral release of the annulus fibrosis was performed during the decompression prior to graft insertion. Postoperative anteroposterior and lateral x-ray imaging confirmed good position of interbody grafts, correction of scoliosis as well as spondylolisthesis, and restoration of disc height achieving foraminal indirect decompression. A routine postoperative x-ray at three months demonstrated asymptomatic ipsilateral cage migration at the L2-3 level with evidence of arthrodesis in the disc space. This was managed conservatively without further surgical intervention. Placement of a lateral plate or interbody intradiscal plating system in patients with scoliosis and significant coronal deformity is an option that can be considered to prevent this rare LLIF complication. Moreover, asymptomatic cage migration may be conservatively managed without reoperation. PMID:26623202

  3. A high-precision instrument for analyzing nonlinear dynamic behavior of bearing cage

    Science.gov (United States)

    Yang, Z.; Chen, H.; Yu, T.; Li, B.

    2016-08-01

    The high-precision ball bearing is fundamental to the performance of complex mechanical systems. As the speed increases, the cage behavior becomes a key factor in influencing the bearing performance, especially life and reliability. This paper develops a high-precision instrument for analyzing nonlinear dynamic behavior of the bearing cage. The trajectory of the rotational center and non-repetitive run-out (NRRO) of the cage are used to evaluate the instability of cage motion. This instrument applied an aerostatic spindle to support and spin test the bearing to decrease the influence of system error. Then, a high-speed camera is used to capture images when the bearing works at high speeds. A 3D trajectory tracking software tema Motion is used to track the spot which marked the cage surface. Finally, by developing the matlab program, a Lissajous' figure was used to evaluate the nonlinear dynamic behavior of the cage with different speeds. The trajectory of rotational center and NRRO of the cage with various speeds are analyzed. The results can be used to predict the initial failure and optimize cage structural parameters. In addition, the repeatability precision of instrument is also validated. In the future, the motorized spindle will be applied to increase testing speed and image processing algorithms will be developed to analyze the trajectory of the cage.

  4. Temporal variation of the static electric field inside an animal cage.

    Science.gov (United States)

    Shigemitsu, T; Tsuchida, Y; Nishiyama, F; Matsumoto, G; Nakamura, H; Shimizu, K

    1981-01-01

    The temporal variation of a static electric field inside an animal cage was investigated with a newly developed small, simple field meter. The field inside the cage was found to be highly dependent on the surface conductivity of the dielectric material. As the surface of the cage became dirty because of animal occupancy, the static electric field inside it became considerably smaller from the moment the field was turned on. Clean cages also modified the static electric field inside them, the field decaying from an initial to a much lower value over several hours. The mechanism of field attenuation for both cases is surface leakage. Surface leakage for a clean cage takes place much more slowly than for a dirty cage. This was confirmed by measuring DC insulation resistance. To examine this phenomenon further, the field in a metal cage width high electrical conductivity was measured. The static electric field inside the metal cage was also found to be reduced. An improved cage design that avoids these problems, is suggested for the study of the biologic effects of static electric fields. PMID:7326060

  5. A stochastic frontier analysis of technical efficiency of fish cage culture in Peninsular Malaysia.

    Science.gov (United States)

    Islam, Gazi Md Nurul; Tai, Shzee Yew; Kusairi, Mohd Noh

    2016-01-01

    Cage culture plays an important role in achieving higher output and generating more export earnings in Malaysia. However, the cost of fingerlings, feed and labour have increased substantially for cage culture in the coastal areas in Peninsular Malaysia. This paper uses farm level data gathered from Manjung, Perak and Kota Tinggi, Johor to investigate the technical efficiency of brackish water fish cage culture using the stochastic frontier approach. The technical efficiency was estimated and specifically the factors affecting technical inefficiencies of fish cage culture system in Malaysia was investigated. On average, 37 percent of the sampled fish cage farms are technically efficient. The results suggest very high degrees of technical inefficiency exist among the cage culturists. This implies that great potential exists to increase fish production through improved efficiency in cage culture management in Peninsular Malaysia. The results indicate that farmers obtained grouper fingerlings from other neighboring countries due to scarcity of fingerlings from wild sources. The cost of feeding for grouper (Epinephelus fuscoguttatus) requires relatively higher costs compared to seabass (Lates calcarifer) production in cage farms in the study areas. Initiatives to undertake extension programmes at the farm level are needed to help cage culturists in utilizing their resources more efficiently in order to substantially enhance their fish production. PMID:27478744

  6. Rearing Laying Hens in Aviaries Reduces Fearfulness following Transfer to Furnished Cages.

    Science.gov (United States)

    Brantsæter, Margrethe; Tahamtani, Fernanda M; Moe, Randi O; Hansen, Tone B; Orritt, Rachel; Nicol, Christine; Janczak, Andrew M

    2016-01-01

    Appropriate rearing is essential for ensuring the welfare and productivity of laying hens. Early experience has the potential to affect the development of fearfulness. This study tested whether rearing in aviaries, as opposed to cages, reduces the fearfulness of laying hens after transfer to furnished cages. Fear responses were recorded as avoidance of a novel object in the home cage. Lohmann Selected Leghorns were reared in an aviary system or conventional rearing cages and then transported to furnished cages at 16 weeks, before the onset of lay. Observations of a selection of birds were conducted at 19 (N = 50 independent cages) and 21 (N = 48 independent cages) weeks of age. At 19 and 21 weeks, cage-reared birds showed higher levels of fearfulness indicated by spending more time away from the novel object compared to aviary-reared birds. These results suggest that rearing in an enriched aviary environment reduces fearfulness up to the fifth week after transfer to a new housing system, compared to rearing in cages. PMID:26955634

  7. Size effect of fullerene cages and encaged clusters in M3N@C2n

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Based on the calculated findings that the sizes of encaged clusters determine the structures and the stability of C80-based trimetallic nitride fullerenes (TNFs), more extensive density functional theory calculations were performed on M3N@C68, M3N@C78 and M3N@C80 (M=Sc, Y and La). The calculated results demonstrated that the structures and stability undergo a transition with the increasing of the sizes of the cages and clusters. Sc3N is planar inside the three considered cages, Y3N is slightly pyramidal inside C68-6140 and C78-5 and planar inside I h C80-7, however, La3N is pyramidal inside all the three cages. Those cages with pyramidal clusters inside deformed considerably, compared with their parent cages. In these cases, the bonding of metallic atoms toward the cages does not play an impor-tant role, and the encaged cluster tends to be located inside the cages with the largest M-M and M-C distances so that the strain energy can be released mostly. These calculations revealed the size effect of fullerene cages and encaged clusters, and can explain the position priority of M3N inside fullerene cages and the differences in yield of M3N@C2n.

  8. Rearing Laying Hens in Aviaries Reduces Fearfulness following Transfer to Furnished Cages

    Science.gov (United States)

    Brantsæter, Margrethe; Tahamtani, Fernanda M.; Moe, Randi O.; Hansen, Tone B.; Orritt, Rachel; Nicol, Christine; Janczak, Andrew M.

    2016-01-01

    Appropriate rearing is essential for ensuring the welfare and productivity of laying hens. Early experience has the potential to affect the development of fearfulness. This study tested whether rearing in aviaries, as opposed to cages, reduces the fearfulness of laying hens after transfer to furnished cages. Fear responses were recorded as avoidance of a novel object in the home cage. Lohmann Selected Leghorns were reared in an aviary system or conventional rearing cages and then transported to furnished cages at 16 weeks, before the onset of lay. Observations of a selection of birds were conducted at 19 (N = 50 independent cages) and 21 (N = 48 independent cages) weeks of age. At 19 and 21 weeks, cage-reared birds showed higher levels of fearfulness indicated by spending more time away from the novel object compared to aviary-reared birds. These results suggest that rearing in an enriched aviary environment reduces fearfulness up to the fifth week after transfer to a new housing system, compared to rearing in cages. PMID:26955634

  9. Effects of Cage Density on the Performance of Laying Hens During High Summer Temperatures

    OpenAIRE

    Altan, Ali; ALTAN, Özge; ÖZKAN, Sezen; ÖZKAN, Kahraman; AKBAŞ, Yavuz; Ayhan, Veysel

    2002-01-01

    This study was conducted to determine the effects of different cage densities on laying performance of white and brown hybrid layers during high summer temperatures. White layers, 68 weeks of age, were housed at a density of 3, 4 or 5 hens/cage (respectively 640, 480 and 384 cm2/hen); brown layers were housed at 3 or 4 hens/cage (respectively 640 and 480 cm2/hen). The results indicated that housing at 3 or 4 hens/cage did not affect egg production or egg quality significantly. Increasing t...

  10. Effects of Nominal Differences in Cage Height and Floor Space on the Wellbeing of Rabbits.

    Science.gov (United States)

    Stewart, Kay L; Suckow, Mark A

    2016-03-01

    The 8th edition of the Guide for the Care and Use of Laboratory Animals recommends a cage height of 16 in. for rabbits, compared with 14 in. in the previous edition. In contrast, the Animal Welfare Act Regulations prescribes a cage height of 14 in. for rabbits. A review of the literature failed to identify published data that support an advantage to rabbits having 16 in. of cage height compared with 14 or 15 in. The study described here evaluated the effect of a 3-in. difference in cage height on the health, growth, behavior, and overall wellbeing of rabbits. Groups of 10 New Zealand white rabbits were housed in cages that provided either 15 in. of interior cage height (720 in(2) of floor space) or 18 in. of interior height (784 in(2) of floor space). The rabbits were observed during 25 periods (1 h each) over 7 wk, and various behavioral parameters were scored. In addition, rabbits were weighed weekly, and general clinical health was assessed. After 4 wk, the groups were switched to the alternate housing. No significant differences in body weight gain or behavioral parameters were detected between groups housed in cages with different heights and amounts of floor space, nor were significant behavioral differences noted in individual rabbits when moved from one cage type to the other. In addition, all rabbits remained clinically healthy throughout the study. These results demonstrate that these differences in interior cage height neither benefit nor harm rabbits. PMID:27025808

  11. The effects of climbing cages on behaviour of female mink during the lactation period

    DEFF Research Database (Denmark)

    Lidfors, L.; Axelsson, H.; Loberg, J.;

    2012-01-01

    The aim was to investigate if there were differences in behaviour of female mink when kept in a climbing cage compared with a standard cage during the lactation period. The study was carried out on 90 mink of the colour type "black cross". Females were housed in either climbing cages (4.350 cm², n......=46) or standard cages (2.550 cm², n=44). Behavioural observations were made four weeks before birth until kits were nine weeks old with one-zero sampling during two hours before feeding. During week 1-4 after females had given birth they were mostly recorded in the nest box and there were no...... differences between cage types. Week 5-8 after giving birth females in climbing cages were less in the nest box, less active out in the cage and had fewer abnormal behaviours, but were on the platforms and more inactive out in the cage. In the bottom cage females were more often walking, grooming and inactive...

  12. Mining the bulk positron lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Aourag, H.; Guittom, A. [Centre de Recherche Nucleaire d' Alger (CRNA), Alger Gare - Algiers (Algeria)

    2009-02-15

    We introduce a new approach to investigate the bulk positron lifetimes of new systems based on data-mining techniques. Through data mining of bulk positron lifetimes, we demonstrate the ability to predict the positron lifetimes of new semiconductors on the basis of available semiconductor data already studied. Informatics techniques have been applied to bulk positron lifetimes for different tetrahedrally bounded semiconductors in order to discover computational design rules. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  13. Mining the bulk positron lifetime

    International Nuclear Information System (INIS)

    We introduce a new approach to investigate the bulk positron lifetimes of new systems based on data-mining techniques. Through data mining of bulk positron lifetimes, we demonstrate the ability to predict the positron lifetimes of new semiconductors on the basis of available semiconductor data already studied. Informatics techniques have been applied to bulk positron lifetimes for different tetrahedrally bounded semiconductors in order to discover computational design rules. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  14. Advances in bulk port development

    Energy Technology Data Exchange (ETDEWEB)

    Soros, P. (Soros Associates Consulting Engineers, New York, NY (USA))

    1991-03-01

    The article features several recently developed bulk ports which illustrate aspects of new technology or concepts in maritime transport. Low handling capacity bulk terminals at Ponta da Madeira, Brazil and Kooragang Island, Australia and the low-cost bulk port at Port of Corpus Christi, Texas are described. Operations at the ports of Pecket and Tocopilla in Chile, which had special technical problems, are mentioned. Coal terminals at Port Kembla, Australia and St. Johns River in Florid Jacksonville, Florida are featured as examples of terminals which had to be designed to meet high environmental standards. 13 refs., 2 figs., 14 photos.

  15. Characterization of manures from fish cage farming in Chile.

    Science.gov (United States)

    Salazar, F J; Saldana, R C

    2007-12-01

    This study aims to characterize salmonid manures and to determine their potential use in agricultural soils. Sampling was carried out below salmon and trout cages in farms located in lakes and in the sea in the South of Chile during 2002-2003. Manure was analyzed for macronutrients, micronutrients and heavy metals. Results showed a high variability between samples and differences between sea and lake manure. Dry matter contents were low averaging c. 12-15%. Manures showed low OM contents with values heavy metal contents and a potential use in agricultural soils, which could reduce the risks of water pollution on water from fish farming. PMID:16962324

  16. DESIGN OF AUTOMATED ROTORY CAGE TYPE FIXTURE FOR CYLINDER BLOCK

    Directory of Open Access Journals (Sweden)

    Y.S.Kapnichor

    2014-07-01

    Full Text Available Project gives feasible solution to move and rotate the component with full proofing fixturing for special purpose operations like drilling, Tapping, deburring, washing, drying involve in manufacturing and assembly unit of industry. Rotary cage type fixture is made for handling the cylinder head inside the cleaning machine use for making fully ready component before assembly operation .System is useful to save time manpower and deliver perfect cleaned and dry component .system involved all the mechanical components along with the sensors used to restrict the rotating operations, stop and go operations etc.

  17. Design of Automated Rotory Cage Type Fixture for Cylinder Block

    Directory of Open Access Journals (Sweden)

    Y.S.Kapnichor

    2014-08-01

    Full Text Available Project gives feasible solution to move and rotate the component with full proofing fixturing for special purpose operations like drilling, Tapping, deburring, washing, drying involve in manufacturing and assembly unit of industry. Rotary cage type fixture is made for handling the cylinder head inside the cleaning machine use for making fully ready component before assembly operation .System is useful to save time manpower and deliver perfect cleaned and dry component .system involved all the mechanical components along with the sensors used to restrict the rotating operations, stop and go operations etc.

  18. Experimental Determination of Stray Load Losses in Cage Induction Machines

    OpenAIRE

    Aoulkadi, M´hamed

    2011-01-01

    With different purposeful measurements like for the stray load losses and the flux densities, on two low-voltage squirrel-cage rotor asynchronous generators for 1.5 MW wind turbines with different types of the stator winding (litz and round wire), the sources of the losses and the causes for the winding overheating are localized and defined. Different measures to reduce the stray load losses due the skin effect in the stator of the round wire winding generator are successfully tested and impl...

  19. Regioselective nitration of aromatic substrates in zeolite cages

    Indian Academy of Sciences (India)

    T Esakkidurai; M Kumarraja; K Pitchumani

    2003-04-01

    Phenol is nitrated regioselectively by fuming nitric acid inside the cages of faujasite zeolites (dependent on the loading level) and a remarkable orthoselectivity is observed in solid state nitration. Toluene and chlorobenzene also containing ortho-/para-orienting substituents, undergo faster nitration, though the regioselectivity is less significant in zeolite media. The results are explained on the basis of diffusion and binding of phenol inside zeolite, which facilitate regioselectivity (and which is absent in toluene and chlorobenzene). Other advantages of employing zeolites as media for mild and selective nitration are also highlighted.

  20. Preinjector for Linac 1, inside the Faraday cage

    CERN Multimedia

    1974-01-01

    For a description of the Linac 1 preinjector, please see first 7403070X. Here, the view is towards the upper level of the Faraday cage. Far to the right, a technician is peering through the service door. The huge box-shaped cubicle is the electronics platform, at 520 kV potential during operation. The "bull eye" at the left back sits at the top end of the accelerating column (see 7403081X) and houses the ion source with its electronics (see 7403083X). The SAMES generator, providing the 520 kV HV (7403074) sits on the floor and is not visible here.

  1. Bulk Nuclear Properties from Reactions

    OpenAIRE

    Danielewicz, P.

    2002-01-01

    Extraction of bulk nuclear properties by comparing reaction observables to results from semiclassical transport-model simulations is discussed. Specific properties include the nuclear viscosity, incompressibility and constraints on the nuclear pressure at supranormal densities.

  2. Bulk charges in eleven dimensions

    CERN Document Server

    Hawking, Stephen William

    1998-01-01

    Eleven dimensional supergravity has electric type currents arising from the Chern-Simon and anomaly terms in the action. However the bulk charge integrates to zero for asymptotically flat solutions with topological trivial spatial sections. We show that by relaxing the boundary conditions to generalisations of the ALE and ALF boundary conditions in four dimensions one can obtain static solutions with a bulk charge preserving between 1/16 and 1/4 of the supersymmetries. One can introduce membranes with the same sign of charge into these backgrounds. This raises the possibility that these generalized membranes might decay quantum mechanically to leave just a bulk distribution of charge. Alternatively and more probably, a bulk distribution of charge can decay into a collection of singlely charged membranes. Dimensional reductions of these solutions lead to novel representations of extreme black holes in four dimensions with up to four charges. We discuss how the eleven-dimensional Kaluza-Klein monopole wrapped a...

  3. Anterior cervical discectomy and fusion: Comparison of titanium and polyetheretherketone cages

    Directory of Open Access Journals (Sweden)

    Cabraja Mario

    2012-09-01

    Full Text Available Abstract Background Titanium (TTN cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical discectomy and fusion (ACDF and therefore might lead to a higher loss of correction. We compared the long term results of stand-alone PEEK- and TTN-cages in a comparable patient collective that was operated under identical operative settings. Methods From 2002 to 2007 154 patients underwent single-level ACDF for degenerative disc disease (DDD. Clinical and radiological outcome were assessed in 86 eligible patients after a mean of 28.4 months. 44 patients received a TTN- and 42 patients a PEEK-cage. Results Solid arthrodesis was found in 93.2% of the TTN-group and 88.1% of the PEEK-group. Cage subsidence was observed in 20.5% of the TTN- and 14.3% of the PEEK-group. A significant segmental lordotic correction was achieved by both cage-types. Even though a loss of correction was found at the last follow-up in both groups, it did not reach the level of statistical significance. Statistical analysis of these results revealed no differences between the TTN- and PEEK-group. When assessed with the neck disability index (NDI, the visual analogue scale (VAS of neck and arm pain and Odom’s criteria the clinical data showed no significant differences between the groups. Conclusions Clinical and radiological outcomes of ACDF with TTN- or PEEK-cages do not appear to be influenced by the chosen synthetic graft. The modulus of elasticity represents only one of many physical properties of a cage. Design, shape, size, surface architecture of a cage as well as bone density, endplate preparation and applied distraction during surgery need to be considered as further important factors.

  4. Outcome of single level anterior cervical discectomy and fusion using nano-hydroxyapatite/polyamide-66 cage

    Directory of Open Access Journals (Sweden)

    Xi Yang

    2014-01-01

    Full Text Available Background: Cages have been widely used for the anterior reconstruction and fusion of cervical spine. Nonmetal cages have become popular due to prominent stress shielding and high rate of subsidence of metallic cages. This study aims to assess fusion with n-HA/PA66 cage following one level anterior cervical discectomy. Materials and Methods: Forty seven consecutive patients with radiculopathy or myelopathy underwent single level ACDF using n-HA/PA66 cage. We measured the segmental lordosis and intervertebral disc height on preoperative radiographs and then calculated the loss of segmental lordosis correction and cage subsidence over followup. Fusion status was evaluated on CT scans. Odom criteria, Japanese Orthopedic Association (JOA and Visual Analog Pain Scales (VAS scores were used to assess the clinical results. Statistically quantitative data were analyzed while Categorical data by χ2 test. Results: Mean correction of segmental lordosis from surgery was 6.9 ± 3.0° with a mean loss of correction of 1.7 ± 1.9°. Mean cage subsidence was 1.2 ± 0.6 mm and the rate of cage subsidence (>2 mm was 2%. The rate of fusion success was 100%. No significant difference was found on clinical or radiographic outcomes between the patients (n=27 who were fused by n-HA/PA66 cage with pure local bone and the ones (n=20 with hybrid bone (local bone associating with bone from iliac crest. Conclusions: The n-HA/PA66 cage is a satisfactory reconstructing implant after anterior cervical discectomy, which can effectively promote bone graft fusion and prevent cage subsidence.

  5. Animal welfare beyond the cage...and beyond the evidence?

    Science.gov (United States)

    Blanchard, Robert J

    2010-01-01

    In "Laboratory Rodent Welfare: Thinking Outside the Cage," Balcombe (2010/this issue) suggests that laboratory cage housing is damaging to rats and mice because it does not meet their evolved needs and may damage their psychological and physical health. The article also indicates that larger and more enriched spaces reduce aggression and mortality and improve the health and friendliness of rodents in the laboratory. Remarkably, many of the studies cited as supporting these assertions fail to provide data bearing on the issues involved or may even report findings opposite to those described by Balcombe, whereas many studies that are highly relevant to these issues are not cited or described. Moreover, although the "evolved needs" of rats and mice are presented as the basis for an analysis of rodent welfare, the important and well-documented changes in needs- or motivation-related behaviors of a rodent in the laboratory (due to human selection over hundreds of generations) is ignored. This pattern of disconnections between data and conclusions is so pervasive as to demolish the scientific value of the exposition. PMID:20017049

  6. [Supplementation of swine feed rations with zeolite during cage rearing].

    Science.gov (United States)

    Bartko, P; Chabada, J; Vrzgula, L; Solár, I; Blazovský, J

    1983-07-01

    The effect of the addition of zeolite to pig feed ration was studied in the cage rearing system under production conditions. Zeolite was mixed in the COS I and COS II feed mixtures directly in the feed plant, the mixing ratio being 100 kg feed mixture + 5 kg zeolite. The feed mixture was administered in granular form ad libitum. The test group had 648 weanlings and the control group 674 weanlings; the piglets, kept in two-story cages in four sections, were arranged so that the test group could be a mirror-like reflection of the control group. The trial lasted 45 days. The piglets given the fortified feed ration had daily weight gains higher by 0.017 kg and feed consumption lower by 0.234 kg per 1 kg of gain, as compared with the control animals. The costs of the feed ration required for producing a kilogram of gain were 8.55 Cz. crowns in the zeolite group and 9.422 crowns in the control group. PMID:6312666

  7. Optical triggered seizures using a caged 4-Aminopyridine

    Directory of Open Access Journals (Sweden)

    Mingrui eZhao

    2015-02-01

    Full Text Available Animal models of epilepsy are critical not only for understanding the fundamental mechanism of epilepsy but also for testing the efficacy of new antiepileptic drugs and novel therapeutic interventions. Photorelease of caged molecules is widely used in biological research to control pharmacologic events with high spatio-temporal resolution. We developed a technique for in vivo optical triggering of neocortical seizures using a novel caged compound based on ruthenium photochemistry (RuBi-4AP. Epileptiform events were induced with blue light illumination. Multi-electrode array recording and optical techniques were used to characterize the propagation of these epileptic events. Epileptiform events including interictal spikes, polyspikes, and ictal discharges were induced with blue light illumination. This model can be induced in vivo with both whole brain and focal illumination to provide high spatio-temporal control of the site of ictal onset. These results demonstrate a novel optically-triggered seizure model that may have widespread application in the investigation of ictal onset, propagation and in novel light-based therapeutic interventions.

  8. Abnormal behavior in caged birds kept as pets.

    Science.gov (United States)

    van Hoek, C S; ten Cate, C

    1998-01-01

    There are a limited number of studies dealing with abnormal behavior in caged birds kept as pets. However, these studies demonstrate the presence of abnormal behavior in both songbirds and parrots. Ethological studies on these birds, as well as studies on domestic and zoo birds, indicate that inappropriate rearing and housing conditions may lead to behavioral abnormalities. Together these data indicate that behavioral abnormalities occur among both wild-caught and domesticated pet birds. The severity and magnitude of these abnormalities is probably underestimated, and there is a need for systematic studies on the nature, origin, variability, species-specificity, and reversibility of behavioral problems in pet birds. Abnormal behavior in caged birds may to some extent be prevented and reduced by environmental enrichment. However, most enrichment studies are anecdotal and not based on a thorough analysis of the behavioral abnormalities, which may lead to measures resulting in a reduction of symptoms rather than the underlying causes. Although it is likely that several of these problems could be reduced by modifying rearing and housing conditions, the current insights into the causal mechanisms underlying abnormal behavior of domesticated and wild-caught pet birds are limited, as are the insights into the possibilities of preventing or curing abnormal behavior. PMID:16363987

  9. Protection characteristics of a Faraday cage compromised by lightning burnthrough.

    Energy Technology Data Exchange (ETDEWEB)

    Warne, Larry Kevin; Bystrom, Edward; Jorgenson, Roy Eberhardt; Montoya, Sandra L.; Merewether, Kimball O.; Coats, Rebecca Sue; Martinez, Leonard E.; Jojola, John M.

    2012-01-01

    A lightning flash consists of multiple, high-amplitude but short duration return strokes. Between the return strokes is a lower amplitude, continuing current which flows for longer duration. If the walls of a Faraday cage are made of thin enough metal, the continuing current can melt a hole through the metal in a process called burnthrough. A subsequent return stroke can couple energy through this newly-formed hole. This LDRD is a study of the protection provided by a Faraday cage when it has been compromised by burnthrough. We initially repeated some previous experiments and expanded on them in terms of scope and diagnostics to form a knowledge baseline of the coupling phenomena. We then used a combination of experiment, analysis and numerical modeling to study four coupling mechanisms: indirect electric field coupling, indirect magnetic field coupling, conduction through plasma and breakdown through the hole. We discovered voltages higher than those encountered in the previous set of experiments (on the order of several hundreds of volts).

  10. Cage Versus Noncage Laying-Hen Housings: Respiratory Exposures.

    Science.gov (United States)

    Arteaga, Veronica; Mitchell, Diane; Armitage, Tracey; Tancredi, Daniel; Schenker, Marc; Mitloehner, Frank

    2015-01-01

    The objective of this study was to compare the personal respiratory exposures of poultry workers in three different types of layer housing under commercial production conditions. Workers were randomly assigned to each of conventional cage, enriched cage, and aviary barns in a crossover repeated-measures design for three observation periods over the hens' lifetime. Inhalable and fine particulate matter (PM) and endotoxin in both size fractions were assessed by personal and area samplers over the work shift. Concentrations of inhalable PM, PM2.5 (PM with an aerodynamic diameter Geometric means (95% confidence intervals [CIs]) of inhalable PM and endotoxin for the aviary, conventional, and enriched barns were 8.9 (6.8-11.5) mg/m(3) and 7517.9 (5403.2-10,460.2) EU/m(3), 3.7 (2.8-4.8) mg/m(3) and 1655.7 (1144.6-2395.2) EU/m(3), 2.4 (1.8-3.3) mg/m(3) and 1404.8 (983.3-2007.0) EU/m(3), respectively. Area samplers recorded a lower mean inhalable PM concentration and higher PM2.5 concentration than personal samplers. Ammonia concentrations were low throughout three monitoring seasons. These findings show that the aviary barns pose higher respiratory exposures to poultry workers than either conventional or enriched barns. PMID:26237714

  11. Large-scale clustering of CAGE tag expression data

    Directory of Open Access Journals (Sweden)

    Kawai Jun

    2007-05-01

    Full Text Available Abstract Background Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs that are differentially utilized in different tissues and cell lines. We have identified a huge number of TSSs mapped onto the mouse genome using the cap analysis of gene expression (CAGE method. The standard hierarchical clustering algorithm, which gives us easily understandable graphical tree images, has difficulties in processing such huge amounts of TSS data and a better method to calculate and display the results is needed. Results We use a combination of hierarchical and non-hierarchical clustering to cluster expression profiles of TSSs based on a large amount of CAGE data to profit from the best of both methods. We processed the genome-wide expression data, including 159,075 TSSs derived from 127 RNA samples of various organs of mouse, and succeeded in categorizing them into 70–100 clusters. The clusters exhibited intriguing biological features: a cluster supergroup with a ubiquitous expression profile, tissue-specific patterns, a distinct distribution of non-coding RNA and functional TSS groups. Conclusion Our approach succeeded in greatly reducing the calculation cost, and is an appropriate solution for analyzing large-scale TSS usage data.

  12. Cage Opening of a Carborane Ligand by Metal Cluster Complexes.

    Science.gov (United States)

    Adams, Richard D; Kiprotich, Joseph; Peryshkov, Dmitry V; Wong, Yuen Onn

    2016-05-01

    The reaction of Os3 (CO)10 (NCMe)2 with closo-o-C2 B10 H10 has yielded two interconvertible isomers Os3 (CO)9 (μ3 -4,5,9-C2 B10 H8 )(μ-H)2 (1 a) and Os3 (CO)9 (μ3 -3,4,8-C2 B10 H8 )(μ-H)2 (1 b) formed by the loss of the two NCMe ligands and one CO ligand from the Os3 cluster. Two BH bonds of the o-C2 B10 H10 were activated in its addition to the osmium cluster. A second triosmium cluster was added to the 1 a/1 b mixture to yield the complex Os3 (CO)9 (μ-H)2 (μ3 -4,5,9-μ3 -7,11,12-C2 B10 H7 )Os3 (CO)9 (μ-H)3 (2) that contains two triosmium triangles attached to the same carborane cage. When heated, 2 was transformed to the complex Os3 (CO)9 (μ-H)(μ3 -3,4,8-μ3 -7,11,12-C2 B10 H8 )Os3 (CO)9 (μ-H) (3) by a novel opening of the carborane cage with loss of H2 . PMID:26971388

  13. Self-Assembly, Guest Capture, and NMR Spectroscopy of a Metal-Organic Cage in Water

    Science.gov (United States)

    Go, Eun Bin; Srisuknimit, Veerasak; Cheng, Stephanie L.; Vosburg, David A.

    2016-01-01

    A green organic-inorganic laboratory experiment has been developed in which students prepare a self-assembling iron cage in D[subscript 2]O at room temperature. The tetrahedral cage captures a small, neutral molecule such as cyclohexane or tetrahydrofuran. [Superscript 1]H NMR analysis distinguishes captured and free guests through diagnostic…

  14. Biomechanische Untersuchung eines biodegradierbaren Cages zur interkorporellen Spondylodese der Halswirbelsäule.

    OpenAIRE

    Gumnior, Sarah Nicole Stephanie

    2010-01-01

    Biomechanical evaluation of a biodegradable cage for interbody fusion at the cervical spine Biomechanical evaluation of a biodegradable cage for interbody fusion in the cervical spine. A in vivo animal study in a sheep model.   Abstract Background Anterior interbody fusion using an intervertebral spacer is a widely accepted surgical treatment for patients with degenerative and traumatic cervical spinal-c...

  15. Healing properties of allograft from alendronate-treated animal in lumbar spine interbody cage fusion.

    Science.gov (United States)

    Xue, Qingyun; Li, Haisheng; Zou, Xuenong; Bünger, Mathias; Egund, Niels; Lind, Martin; Christensen, Finn Bjarke; Bünger, Cody

    2005-04-01

    This study investigated the healing potential of allograft from bisphosphonate-treated animals in anterior lumbar spine interbody fusion. Three levels of anterior lumbar interbody fusion with Brantigan cages were performed in two groups of five landrace pigs. Empty Brantigan cages or cages filled with either autograft or allograft were located randomly at different levels. The allograft materials for the treatment group were taken from the pigs that had been fed with alendronate, 10 mg daily for 3 months. The histological fusion rate was 2/5 in alendronate-treated allograft and 3/5 in non-treated allograft. The mean bone volume was 39% and 37.2% in alendronate-treated or non-treated allograft (NS), respectively. No statistical difference was found between the same grafted cage comparing two groups. The histological fusion rate was 7/10 in all autograft cage levels and 5/10 in combined allograft cage levels. No fusion was found at all in empty cage levels. With the numbers available, no statistically significant difference was found in histological fusion between autograft and allograft applications. There was a significant difference of mean bone volume between autograft (49.2%) and empty cage (27.5%) (P<0.01). In conclusion, this study did not demonstrate different healing properties of alendronate-treated and non-treated allograft for anterior lumbar interbody fusion in pigs. PMID:15248057

  16. Animal Welfare and Food Safety Aspects of Confining Broiler Chickens to Cages.

    Science.gov (United States)

    Shields, Sara; Greger, Michael

    2013-01-01

    In most areas of the world, broiler chickens are raised in floor systems, but cage confinement is becoming more common. The welfare of broiler chickens in cages is affected by movement restriction, poor bone strength due to lack of exercise, and prevention of key behavioral patterns such as dustbathing and ground scratching. Cages for broiler chickens also have a long history of causing skin and leg conditions that could further compromise welfare, but a lack of controlled studies makes it difficult to draw conclusions about newer cage designs. Cage environments are usually stocked at a higher density than open floor systems, and the limited studies available suggest that caging may lead to increased levels of fear and stress in the birds. Further, birds reared on the floor appear less likely to harbor and shed Salmonella, as litter may serve as a seeding agent for competitive exclusion by other microorganisms. Cages for laying hens used in egg production have met with substantial opposition due to welfare concerns and caging broiler chickens will likely be subject to the same kinds of social disapproval. PMID:26487409

  17. Design and synthesis of novel bis-annulated caged polycycles via ring-closing metathesis: pushpakenediol

    Directory of Open Access Journals (Sweden)

    Sambasivarao Kotha

    2014-11-01

    Full Text Available Intricate caged molecular frameworks are assembled by an atom economical process via a Diels–Alder (DA reaction, a Claisen rearrangement, a ring-closing metathesis (RCM and an alkenyl Grignard addition. The introduction of olefinic moieties in the pentacycloundecane (PCUD framework at appropriate positions followed by RCM led to the formation of novel heptacyclic cage systems.

  18. Alterations of diaphragm and rib cage morphometry in severe COPD patients by CT analysis.

    Science.gov (United States)

    Salito, C; Luoni, E; Aliverti, A

    2015-08-01

    Although it is known that in patients with COPD acute hyperinflation determines shortening of the inspiratory muscles, its effects on both diaphragm and rib cage morphology are still to be investigated. In this preliminary study the relationships between hyperinflation, emphysema, diaphragm and rib cage geometry were studied in 5 severe COPD patients and 5 healthy subjects. An automatic software was developed to obtain the 3-D reconstruction of diaphragm and rib cage from CT scans taken at total lung capacity (TLC) and residual volume (RV). Dome surface area (Ado), radius of curvature, length (Ld) and position (referred to xiphoid level) of the diaphragm and antero-posterior (A-P) and transverse (T) diameters of rib cage were calculated at both volumes. Ado and Ld were similar in COPD and controls when compared at similar absolute lung volumes. Radius of curvature was significantly higher in COPD than in controls only at TLC. In COPD, the range of diaphragm position was invariantly below the xiphoid level, while in controls the top of diaphragm dome was always above it. Rib cage diameters were not different at TLC. A-P diameter was greater in COPD than in controls at RV, while T diameters were similar. In conclusion, in severe COPD diaphragm and rib cage geometry is altered at RV. The lower position of diaphragm is associated to smaller A-P but not transversal rib cage diameters, such that rib cage adopts a more circular shape. PMID:26737755

  19. Tuneable dynamics of a scandium nitride cluster inside an Ih-C80 cage.

    Science.gov (United States)

    Feng, Yongqiang; Wang, Taishan; Xiang, Junfeng; Gan, Lihua; Wu, Bo; Jiang, Li; Wang, Chunru

    2015-02-01

    The internal clusters in metallofullerenes usually exhibit certain motion that is potentially usable in molecular gyroscopes and nano-machines. Based on (45)Sc NMR, the motion of the scandium nitride cluster within the C80 cage was investigated via varying the temperature and modifying the cage, and by changing the cluster size. PMID:25558825

  20. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    NARCIS (Netherlands)

    Williams, G.R.; Alaux, C.; Costa, C.; Csaki, C.; Steen, van der J.J.M.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may c

  1. Immobilization of two organometallic complexes into a single cage to construct protein-based microcompartments.

    Science.gov (United States)

    Maity, Basudev; Fukumori, Kazuki; Abe, Satoshi; Ueno, Takafumi

    2016-04-01

    Natural protein-based microcompartments containing multiple enzymes promote cascade reactions within cells. We use the apo-ferritin protein cage to mimic such biocompartments by immobilizing two organometallic Ir and Pd complexes into the single protein cage. Precise locations of the metals and their accumulation mechanism were studied by X-ray crystallography. PMID:27021005

  2. Recombinant expression and purification of 'virus-like' bacterial encapsulin protein cages

    NARCIS (Netherlands)

    Rurup, W.F.; Cornelissen, J.J.L.M.; Koay, M.S.T.; Orner, Brendan P.

    2014-01-01

    Ultracentrifugation, particularly the use of sucrose or cesium chloride density gradients, is a highly reliable and efficient technique for the purification of virus-like particles and protein cages. Since virus-like particles and protein cages have a unique size compared to cellular macromolecules

  3. Modulation of aggression in male mice : influence of group size and cage size

    NARCIS (Netherlands)

    Van Loo, PLP; Mol, JA; Koolhaas, JM; Van Zutphen, BFM; Baumans, [No Value; Koolhaas, Jaap M.; Zutphen, Bert F.M. van; Baumans, Vera

    2001-01-01

    Aggression in group-housed male mice is known to be influenced by both cage size and group size. However, the interdependency of these two parameters has not been studied yet. In this study, the level of aggression in groups of three, five, or eight male BALB/c mice housed in cages with a floor size

  4. A pyrrolo-tetrathiafulvalene cage: Synthesis and X-ray crystal structure

    DEFF Research Database (Denmark)

    Nielsen, Kent A.; Jeppesen, Jan O.; Levillain, Eric;

    2002-01-01

    A novel type of tetrathiafulvalene-cage 4 containing three monopyrrolo-tetrathiafulvalene units has been prepared employing a general and efficient synthetic approach. X-ray crystal structure analysis revealed that the cage is able to accommodate solvent molecules within a cavity in the solid state....

  5. Negative-Index Media for Matter-Wave Optics

    Science.gov (United States)

    Baudon, J.; Hamamda, M.; Grucker, J.; Boustimi, M.; Perales, F.; Dutier, G.; Ducloy, M.

    2009-04-01

    We consider the extension of optical metamaterials to matter waves and then the down scaling of metaoptics to nanometric wavelengths. We show that the generic property of pulsed comoving magnetic fields allows us to fashion the wave-number dependence of the atomic phase shift. It can be used to produce a transient negative group velocity of an atomic wave packet, which results into a negative refraction of the matter wave. Application to slow metastable argon atoms Ar*(P23) shows that the device is able to operate either as an efficient beam splitter or an atomic metalens.

  6. Soft 3D acoustic metamaterial with negative index.

    Science.gov (United States)

    Brunet, Thomas; Merlin, Aurore; Mascaro, Benoit; Zimny, Kevin; Leng, Jacques; Poncelet, Olivier; Aristégui, Christophe; Mondain-Monval, Olivier

    2015-04-01

    Many efforts have been devoted to the design and achievement of negative-refractive-index metamaterials since the 2000s. One of the challenges at present is to extend that field beyond electromagnetism by realizing three-dimensional (3D) media with negative acoustic indices. We report a new class of locally resonant ultrasonic metafluids consisting of a concentrated suspension of macroporous microbeads engineered using soft-matter techniques. The propagation of Gaussian pulses within these random distributions of 'ultra-slow' Mie resonators is investigated through in situ ultrasonic experiments. The real part of the acoustic index is shown to be negative (up to almost - 1) over broad frequency bandwidths, depending on the volume fraction of the microbeads as predicted by multiple-scattering calculations. These soft 3D acoustic metamaterials open the way for key applications such as sub-wavelength imaging and transformation acoustics, which require the production of acoustic devices with negative or zero-valued indices. PMID:25502100

  7. Soft 3D acoustic metamaterial with negative index

    Science.gov (United States)

    Brunet, Thomas; Merlin, Aurore; Mascaro, Benoit; Zimny, Kevin; Leng, Jacques; Poncelet, Olivier; Aristégui, Christophe; Mondain-Monval, Olivier

    2015-04-01

    Many efforts have been devoted to the design and achievement of negative-refractive-index metamaterials since the 2000s. One of the challenges at present is to extend that field beyond electromagnetism by realizing three-dimensional (3D) media with negative acoustic indices. We report a new class of locally resonant ultrasonic metafluids consisting of a concentrated suspension of macroporous microbeads engineered using soft-matter techniques. The propagation of Gaussian pulses within these random distributions of ‘ultra-slow’ Mie resonators is investigated through in situ ultrasonic experiments. The real part of the acoustic index is shown to be negative (up to almost - 1) over broad frequency bandwidths, depending on the volume fraction of the microbeads as predicted by multiple-scattering calculations. These soft 3D acoustic metamaterials open the way for key applications such as sub-wavelength imaging and transformation acoustics, which require the production of acoustic devices with negative or zero-valued indices.

  8. Negative-Index Media for Matter-Wave Optics

    International Nuclear Information System (INIS)

    We consider the extension of optical metamaterials to matter waves and then the down scaling of metaoptics to nanometric wavelengths. We show that the generic property of pulsed comoving magnetic fields allows us to fashion the wave-number dependence of the atomic phase shift. It can be used to produce a transient negative group velocity of an atomic wave packet, which results into a negative refraction of the matter wave. Application to slow metastable argon atoms Ar*(3P2) shows that the device is able to operate either as an efficient beam splitter or an atomic metalens

  9. Solid state and aqueous behavior of uranyl peroxide cage clusters

    Science.gov (United States)

    Pellegrini, Kristi Lynn

    Uranyl peroxide cage clusters include a large family of more than 50 published clusters of a variety of sizes, which can incorporate various ligands including pyrophosphate and oxalate. Previous studies have reported that uranyl clusters can be used as a method to separate uranium from a solid matrix, with potential applications in reprocessing of irradiated nuclear fuel. Because of the potential applications of these novel structures in an advanced nuclear fuel cycle and their likely presence in areas of contamination, it is important to understand their behavior in both solid state and aqueous systems, including complex environments where other ions are present. In this thesis, I examine the aqueous behavior of U24Pp 12, as well as aqueous cluster systems with added mono-, di-, and trivalent cations. The resulting solutions were analyzed using dynamic light scattering and ultra-small angle X-ray scattering to evaluate the species in solution. Precipitates of these systems were analyzed using powder X-ray diffraction, X-ray fluorescence spectrometry, and Raman spectroscopy. The results of these analyses demonstrate the importance of cation size, charge, and concentration of added cations on the aqueous behavior of uranium macroions. Specifically, aggregates of various sizes and shapes form rapidly upon addition of cations, and in some cases these aggregates appear to precipitate into an X-ray amorphous material that still contains U24Pp12 clusters. In addition, I probe aggregation of U24Pp12 and U60, another uranyl peroxide cage cluster, in mixed solvent water-alcohol systems. The aggregation of uranyl clusters in water-alcohol systems is a result of hydrogen bonding with polar organic molecules and the reduction of the dielectric constant of the system. Studies of aggregation of uranyl clusters also allow for comparison between the newer uranyl polyoxometalate family and century-old transition metal polyoxometalates. To complement the solution studies of uranyl

  10. Environmental enrichment reduces signs of boredom in caged mink.

    Directory of Open Access Journals (Sweden)

    Rebecca K Meagher

    Full Text Available Animals housed in impoverished cages are often labelled 'bored'. They have also been called 'apathetic' or 'depressed', particularly when profoundly inactive. However, these terms are rarely operationally defined and validated. As a negative state caused by under-stimulation, boredom should increase interest in stimuli of all kinds. Apathy (lack of interest, by contrast, should manifest as decreased interest in all stimuli, while anhedonia (loss of pleasure, a depressive symptom should specifically decrease interest in normally rewarding stimuli. We tested the hypotheses that mink, a model carnivore, experience more boredom, depression-like apathy, or anhedonia in non-enriched (NE cages than in complex, enriched (E cages. We exposed 29 subjects (13 E, 16 NE to ten stimuli categorized a priori as aversive (e.g. air puffs, rewarding (e.g. evoking chasing or ambiguous/neutral (e.g. candles. Interest in stimuli was assessed via latencies to contact, contact durations, and durations oriented to stimuli. NE mink contacted all stimuli faster (P = 0.003 than E mink, and spent longer oriented to/in contact with them, albeit only significantly so for ambiguous ones (treatment*type P<0.013. With stimulus category removed from statistical models, interest in all stimuli was consistently higher among NE mink (P<0.0001 for all measures. NE mink also consumed more food rewards (P = 0.037. Finally, we investigated whether lying down while awake and stereotypic behaviour (both increased by NE housing predicted these responses. Lying awake positively co-varied with certain measures of increased exploration. In contrast, stereotypic 'scrabbling' or locomotion (e.g. pacing did not. Overall, NE mink showed no evidence of apathy or depression, but instead a heightened investigation of diverse stimuli consistent with boredom. This state was potentially indicated by spending much time lying still but awake (although this result requires replication. Boredom can

  11. Outcome of instrumented lumbar fusion for low grade spondylolisthesis; Evaluation of interbody fusion with & without cages

    Science.gov (United States)

    Fathy, Mostafa; Fahmy, Mohamed; Fakhri, Mazen; Aref, Khaled; Abdin, Khaled; Zidan, Ihab

    2010-01-01

    Object: The aim is to evalute the outcome of posterior lumbar interbody fusion with autologous bone graft versus titanium Cages, BAK system (Bagby – Kuslich, Spine Tech, Inc. Minneapolis, MN) for low grade spondyloisthesis (Grade1,11). Interbody cages have been developed to replace tricortical Interbody grafts in posterior lumbar interbody fusion (PLIF) procedures. The cages provide immediate post operative stability and facilitate bony union with cancellous bone packed in the cage itself. METHOD: We Evaluated 50 consecutive patients in whom surgery was performed between June 2000 to June 2003 in the Main Alexandria University Hospital at EGYPT. Twenty five patients were operated using autologous bone graft and 25 patients using the BAK cages. The neuro–radiologic al work up consisted of; plain X – ray lumbosacral spine including dynamic films preoperative and postoperative follow up; C.T lumbosacral spine and MRI lumbosacral spine. The surgery was performed at L4-5 level in 34 cases and at L5-S1 level in 16 cases. The median follow up was 15 months. RESULTS: Satisfactory fusion was obtained at all levels at a minimum one year follow – up. The fusion rate was 96% (24 patients) for the cage group and 80% (20 patients) for bone graft group however clinical improvement was 64% (16 patients) for those with bone graft group. CONCLUSION: A higher fusion rates and a better clinical outcome have been obtained by Instrumented PLIF with titanium cages that with bone graft. Inderbody fusion cages help to stabilize spainal segment primarily by distracting them as well as by allowing bone ingrowth and fusion. The procedure is safe and effective with 96% fusion rate and 76% overall Satisfactory rate. The use of cages help to distract the space between the vertebral bodies making the correction of the degree of spondylolisthesis easier. Long term follow up revealed better fusion rate and better realignment and less resorption with cages than with bone grafts. PMID

  12. Looking for a bulk point

    CERN Document Server

    Maldacena, Juan; Zhiboedov, Alexander

    2015-01-01

    We consider Lorentzian correlators of local operators. In perturbation theory, singularities occur when we can draw a position-space Landau diagram with null lines. In theories with gravity duals, we can also draw Landau diagrams in the bulk. We argue that certain singularities can arise only from bulk diagrams, not from boundary diagrams. As has been previously observed, these singularities are a clear diagnostic of bulk locality. We analyze some properties of these perturbative singularities and discuss their relation to the OPE and the dimensions of double-trace operators. In the exact nonperturbative theory, we expect no singularity at these locations. We prove this statement in 1+1 dimensions by CFT methods.

  13. Gamma probe dry bulk densities

    International Nuclear Information System (INIS)

    The gamma density probe is a useful instrument for measuring water content in small volumes of soil. Essentially, the gamma probe measures the density of the soil and water between a source and a detector. To transpose the gamma densities into water content, the dry bulk density of the soil is needed. A nondestructive method for estimating dry bulk densities for use with the gamma probe is proposed. The procedure is based on the assumption that water content values in a field dry condition were more stable than the dry bulk density values and could be transferred from one point to another. The procedure was successfully used on three areas in Reynolds Creek Experimental Watershed in southwest Idaho. (U.S.)

  14. Bulk Viscosity of Interacting Hadrons

    OpenAIRE

    Wiranata, A.; M. Prakash

    2009-01-01

    We show that first approximations to the bulk viscosity $\\eta_v$ are expressible in terms of factors that depend on the sound speed $v_s$, the enthalpy, and the interaction (elastic and inelastic) cross section. The explicit dependence of $\\eta_v$ on the factor $(\\frac 13 - v_s^2)$ is demonstrated in the Chapman-Enskog approximation as well as the variational and relaxation time approaches. The interesting feature of bulk viscosity is that the dominant contributions at a given temperature ari...

  15. Bulk Viscosity of Interacting Hadrons

    CERN Document Server

    Wiranata, A

    2009-01-01

    We show that first approximations to the bulk viscosity $\\eta_v$ are expressible in terms of factors that depend on the sound speed $v_s$, the enthalpy, and the interaction (elastic and inelastic) cross section. The explicit dependence of $\\eta_v$ on the factor $(\\frac 13 - v_s^2)$ is demonstrated in the Chapman-Enskog approximation as well as the variational and relaxation time approaches. The interesting feature of bulk viscosity is that the dominant contributions at a given temperature arise from particles which are neither extremely nonrelativistic nor extremely relativistic. Numerical results for a model binary mixture are reported.

  16. Resonance Spectra of Caged Stringy Black Hole and Its Spectroscopy

    CERN Document Server

    Sakalli, I

    2015-01-01

    The Maggiore's method (MM), which evaluates the transition frequency that appears in the adiabatic invariant from the highly damped quasinormal mode (QNM) frequencies, is used to investigate the entropy/area spectra of the Garfinkle--Horowitz--Strominger black hole (GHSBH). Instead of the ordinary QNMs, we compute the boxed QNMs (BQNMs) that are the characteristic resonance spectra of the confined scalar fields in the GHSBH geometry. For this purpose, we assume that the GHSBH has a confining cavity (mirror) placed in the vicinity of the event horizon. We then show how the complex resonant frequencies of the caged GHSBH are computed using the Bessel differential equation that arises when the scalar perturbations around the event horizon are considered. Although the entropy/area is characterized by the GHSBH parameters, their quantization is shown to be independent of those parameters. However, both spectra are equally spaced.

  17. Magnetotactic Bacterial Cages as Safe and Smart Gene Delivery Vehicles

    KAUST Repository

    Alsaiari, Shahad K.

    2016-07-27

    In spite of the huge advances in the area of synthetic carriers, their efficiency still poorly compares to natural vectors. Herein, we report the use of unmodified magnetotactic bacteria as a guidable delivery vehicle for DNA functionalized gold nanoparticles (AuNPs). High cargo loading is established under anaerobic conditions (bacteria is alive) through endocytosis where AuNPs are employed as transmembrane proteins mimics (facilitate endocytosis) as well as imaging agents to verify and quantify loading and release. The naturally bio-mineralized magnetosomes, within the bacteria, induce heat generation inside bacteria through magnetic hyperthermia. Most importantly after exposing the system to air (bacteria is dead) the cell wall stays intact providing an efficient bacterial vessel. Upon incubation with THP-1 cells, the magnetotactic bacterial cages (MBCs) adhere to the cell wall and are directly engulfed through the phagocytic activity of these cells. Applying magnetic hyperthermia leads to the dissociation of the bacterial microcarrier and eventual release of cargo.

  18. CAGE Analysis of China’s Trade Globalization

    Directory of Open Access Journals (Sweden)

    Emmanuel Olusegun STOBER

    2014-06-01

    Full Text Available Gravity model of international trade states that trade interaction between two countries is in direct proportion to their size measured by Gross Domestic Product and in inverse proportion to the geographic distance. Conley and Ligon (2001 argued that the relevant economic distance between countries is often not the geographic distance. Thus, this study uses original datasets on economic distance to structure observed variations, to decompose the multidimensional CAGE distance framework of globalization derived from the Newton’s Law of gravitation as it applies to China’s international interaction, to evaluate bilateral trade patterns in identifying and prioritizing the importance of cross-border flows and differences that accounted for the development of China’s global strategies. This study confirms that distance must be accounted for in the decision making of any country’s globalization process or any firm’s global expansion as the effects on cross-border economic activities are enormous.

  19. Electrostatic capacitance and Faraday cage behavior of carbon nanotube forests

    International Nuclear Information System (INIS)

    Understanding of the electrostatic properties of carbon nanotube (CNT) forests is essential to enable their integration in microelectronic and micromechanical devices. In this study, we sought to understand how the hierarchical geometry and morphology of CNT forests determines their capacitance. First, we find that at small gaps, solid micropillars have greater capacitance, yet at larger gaps the capacitance of the CNT forests is greater. The surface area of the CNT forest accessible to the electrostatic field was extracted by analysis of the measured capacitance, and, by relating the capacitance to the average density of CNTs in the forest, we find that the penetration depth of the electrostatic field is on the order of several microns. Therefore, CNT forests can behave as a miniature Faraday cage. The unique electrostatic properties of CNT forests could therefore enable their use as long-range proximity sensors and as shielding elements for miniature electronic devices

  20. Nonlinear vs. linear biasing in Trp-cage folding simulations

    Energy Technology Data Exchange (ETDEWEB)

    Spiwok, Vojtěch, E-mail: spiwokv@vscht.cz; Oborský, Pavel; Králová, Blanka [Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Technická 3, Prague 6 166 28 (Czech Republic); Pazúriková, Jana [Institute of Computer Science, Masaryk University, Botanická 554/68a, 602 00 Brno (Czech Republic); Křenek, Aleš [Institute of Computer Science, Masaryk University, Botanická 554/68a, 602 00 Brno (Czech Republic); Center CERIT-SC, Masaryk Univerzity, Šumavská 416/15, 602 00 Brno (Czech Republic)

    2015-03-21

    Biased simulations have great potential for the study of slow processes, including protein folding. Atomic motions in molecules are nonlinear, which suggests that simulations with enhanced sampling of collective motions traced by nonlinear dimensionality reduction methods may perform better than linear ones. In this study, we compare an unbiased folding simulation of the Trp-cage miniprotein with metadynamics simulations using both linear (principle component analysis) and nonlinear (Isomap) low dimensional embeddings as collective variables. Folding of the mini-protein was successfully simulated in 200 ns simulation with linear biasing and non-linear motion biasing. The folded state was correctly predicted as the free energy minimum in both simulations. We found that the advantage of linear motion biasing is that it can sample a larger conformational space, whereas the advantage of nonlinear motion biasing lies in slightly better resolution of the resulting free energy surface. In terms of sampling efficiency, both methods are comparable.

  1. Nonlinear vs. linear biasing in Trp-cage folding simulations

    International Nuclear Information System (INIS)

    Biased simulations have great potential for the study of slow processes, including protein folding. Atomic motions in molecules are nonlinear, which suggests that simulations with enhanced sampling of collective motions traced by nonlinear dimensionality reduction methods may perform better than linear ones. In this study, we compare an unbiased folding simulation of the Trp-cage miniprotein with metadynamics simulations using both linear (principle component analysis) and nonlinear (Isomap) low dimensional embeddings as collective variables. Folding of the mini-protein was successfully simulated in 200 ns simulation with linear biasing and non-linear motion biasing. The folded state was correctly predicted as the free energy minimum in both simulations. We found that the advantage of linear motion biasing is that it can sample a larger conformational space, whereas the advantage of nonlinear motion biasing lies in slightly better resolution of the resulting free energy surface. In terms of sampling efficiency, both methods are comparable

  2. Gaiola de metabolismo para equinos Metabolism cage for horses

    Directory of Open Access Journals (Sweden)

    Dorinha Miriam Silber Schmidt Vitti

    2000-05-01

    Full Text Available A gaiola de metabolismo, modelo proposto neste trabalho, foi construida na Seção de Oficina da FCAV-Unesp, Jaboticabal-SP e utilizada no Laboratório de Ciências Animais do Cena-USP, Piracicaba-SP. Este equipamento permite alojar eqüinos machos com idade a partir do desmame. Os animais foram treinados (condicionados diariamente a permanecer na gaiola de metabolismo por um período de aproximadamente 30 dias antes do início do experimento. O material necessário e a construção de uma gaiola metabólica para eqüinos machos é descrita e ilustrada. A estrutura principal da gaiola (2,68 m de comprimento x 0,80 m de largura x 2,02 m de altura é constituida por canos de metal de duas polegadas e todas as unidades de apoio - tábuas do piso, grade de urina, bebedouro, comedouro, bandeja coletora de urina e barras de contenção - estão fixas à estrutura principal de modo a serem removidas desta, faciltando o manejo e a limpeza do equipamento. O equipamento foi projetado para alojar animais de vários tamanhos e também para ser efetiva na coleta total de fezes e urina e no fornecimento de alimento e água. Os animais permaneceram em pé durante todo o período de confinamento, sem contudo ter havido a ocorrência de edemas graves nos membros. O modelo proposto foi testado em experimentos de metabolismo de fósforo utilizando-se radioisótopos.The metabolism cage here proposed was built at FCAV-Unesp, Jaboticabal, state of São Paulo, Brazil, and used in the Animal Science Laboratory at Cena-USP, Piracicaba, state of São Paulo, Brazil. The equipment allows to host male horses from weaning to adult age. Before starting the experiment, the animals were daily conditioned for a 30-day period to remain in the cage. The necessary material and the building process of the horse metabolic cage are described and illustrated. The main structure of the cage (2.68m long x 0.80 m wide x 2.02 m high was made of 2-inch-diameter metal tube, and all the

  3. Role of cage material, working style and hearing sensitivity in perception of animal care noise.

    Science.gov (United States)

    Voipio, H-M; Nevalainen, T; Halonen, P; Hakumäki, M; Björk, E

    2006-10-01

    During daily care, laboratory animals are exposed to a variety of sounds which may have effects on welfare and also cause physiological and behavioural changes. So far, almost no attention has been paid to individual sounds or the sound level caused by animal care or the sound level inside the animal cage. In this study, sounds from selected rat care procedures were recorded: pulling cage out of the rack, placing it onto a table and replacing the cage back into the rack; with measurements made inside the rat cage and in the adjacent cage. Diet was poured into the food hopper and sounds were recorded inside the cage and also the adjacent cage. The work was repeated in a calm and also in a hurried style, using stainless steel and polycarbonate cages. Finally, the sounds produced by running tap water were recorded. Differences between rat and human hearing were compared using novel species-specific sound level weightings: R-weighting for rats dB(R) and H-weighting for human dB(H). Hurried work with steel caused sound exposure levels exceeding 90 dB(R) when the cages were placed into the rack and about 80 dB(R) when pulling them out of the rack or placing onto a table. With polycarbonate, the levels were 10-15 dB(R) lower. Unhurried calm working produced lower sound exposure levels than hurried working in many procedures. When the procedures were repeated with measurements in the adjacent cage, the sound exposure levels were lower, but the results were similar. Pouring food pellets into a hopper above the rat's head caused 15 dB(R) higher sound exposure levels than pouring food to an adjacent cage. In general, humans hear these sounds about 10-15 dB louder than rats. In conclusion, cage material, working style and hearing sensitivity all have an impact on the sound exposure level in the rodent cage. With correct working methods, high sound levels can be efficiently avoided in most cases. PMID:17018211

  4. Bulk charges in eleven dimensions

    Science.gov (United States)

    Hawking, S. W.; Taylor-Robinson, M. M.

    1998-07-01

    Eleven dimensional supergravity has electric type currents arising from the Chern-Simon and anomaly terms in the action. However the bulk charge integrates to zero for asymptotically flat solutions with topological trivial spatial sections. We show that by relaxing the boundary conditions to generalisations of the ALE and ALF boundary conditions in four dimensions one can obtain static solutions with a bulk charge. Solutions involving anomaly terms preserve between 1/16 and 1/4 of the supersymmetries but Chern-Simons fluxes generally break all of the remaining supersymmetry. One can introduce membranes with the same sign of charge into these backgrounds. This raises the possibility that these generalized membranes might decay quantum mechanically to leave just a bulk distribution of charge. Alternatively and more probably, a bulk distribution of charge can decay into a collection of singly charged membranes. Dimensional reductions of these solutions lead to novel representations of extreme black holes in four dimensions with up to four charges. We discuss how the eleven-dimensional Kaluza-Klein monopole wrapped around a space with non-zero first Pontryagin class picks up an electric charge proportional to the Pontryagin number.

  5. Bulk viscosity and deflationary universes

    CERN Document Server

    Lima, J A S; Waga, I

    2007-01-01

    We analyze the conditions that make possible the description of entropy generation in the new inflationary model by means of a nearequilibrium process. We show that there are situations in which the bulk viscosity cannot describe particle production during the coherent field oscillations phase.

  6. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja;

    2009-01-01

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise i...

  7. Digestibility and behavior of dogs housed in kennels or metabolic cages

    Directory of Open Access Journals (Sweden)

    Tabyta Tamara Sabchuk

    2012-01-01

    Full Text Available The objective of the present study was to compare the apparent digestibility coefficients of a commercial dog food, fecal consistency and behavior of dogs housed in kennels and metabolic cages. Six adult Beagle dogs were distributed in cross-over experimental design, with six replicates per treatment. Dogs were housed in two environments: metabolic cages and in masonry kennels with solarium. Dogs were fed for a five-day adaptation period, and the five following days were used for total feces collection. Dogs behavior was recorded during a 48-h period, with 10-min intervals. Apparent digestibility coefficients were not different between treatments. However, dogs housed in metabolic cages produced lower weight and more consistent feces as compared with dogs housed in kennels. Dogs spent most of the time sleeping in both housing systems; however, dogs housed in the metabolic cages slept more than those in kennels. Stress-related behaviors (barking, whimpering, stereotypies, etc were observed for no longer than 15 minutes per day, and were not different between dogs in kennels or in cages. There is no difference in food digestibility evaluated in dogs housed in metabolic cages or kennels; however, dogs kept in metabolic cages eliminate drier feces and spend more time inactive than those kept in kennels.

  8. Cage-induced stereotypies, perseveration and the effects of environmental enrichment in laboratory mice.

    Science.gov (United States)

    Gross, Alexandra N; Richter, S Helene; Engel, A Katarina J; Würbel, Hanno

    2012-09-01

    When kept in barren and restrictive cages, animals frequently develop stereotypic behaviour patterns that are characterized by high repetition rates, conspicuous invariance and an apparent lack of function. Although millions of animals are affected, the underlying causes and mechanisms are still unclear. Growing evidence suggests that cage-induced stereotypies may reflect pathological dysfunction within basal ganglia circuitry expressed by perseverative behaviour. In order to assess whether variation in stereotypy performance and variation in perseverative behaviour may have a common cause in ICR CD-1 mice, we assessed the effects of environmental enrichment on both phenomena. We raised 48 female ICR CD-1 mice in standard or enriched cages from three weeks to either 6 or 11 months of age and measured stereotypy level in the home cage and perseveration on an extinction task. We further examined whether enriched rearing conditions (early enrichment) protect mice from the developing stereotypies later in life and whether stereotypies developed in barren cages would persist in an enriched environment (late enrichment) by transferring standard mice to enriched cages and vice versa for 14 weeks after completion of the extinction task. We found no evidence for a causal relation between stereotypy and perseveration in mice. However, transfer to enriched cages reduced stereotypy levels significantly both at 6 and 11 months of age indicating that stereotypies had not become established yet. Finally, we found that removing enrichments at both ages did not induce higher stereotypy levels, thereby confirming earlier reports of a neuroprotective effect of early enrichment. PMID:22721674

  9. Evaluation of the 96/4 PLDLLA polymer resorbable lumbar interbody cage in a long term animal model.

    Science.gov (United States)

    Lazennec, Jean Y; Madi, Abdallah; Rousseau, Marc A; Roger, Bernard; Saillant, Gérard

    2006-10-01

    Arthrodesis using interbody cages has demonstrated high fusion rates. However, permanent cages are exposed to stress-shielding, corrosion, and may require explanation when necessary. Polylactic acid (PLA) bioresorbable cages are developed for avoiding these problems, but significant tissue reaction has been reported with 70/30 PLDLLA in some preclinical animal studies. The objective was to evaluate 96/4 PLDLLA cages in a sheep model over 3 years. Sixteen sheeps underwent one level anterior lumbar interbody fusion using 96/4 PLDLLA cages, filled and surrounded with cancellous bone graft from the iliac crest. Six groups of three animals were killed after 3, 6, 9, 12, 24, and 36 months. Harvested lumbar spine had radiographic, MRI, and CT evaluation and histological analysis. Histological results: cage swelling and slight signs of fragmentation associated to fibrocartilaginous tissue apposition at 3 months; bone remodeling around the cage with direct apposition of the mineralization front at 6 months; active cage degradation and complete fusion around the cage at 9 months; cage fragmentation and partial replacement by bone tissue at 12 months; bone bridges in and around the cage at 24 months; full resorption and intervertebral fusion at 36 months. Radiological results: partial arthrodesis at 3 months; definite peripheral arthrodesis at 6 months; similar aspect at 9 months; significant cage resorption at 12 months; definite inner and outer fusion at 24 months; complete cage resorption and calcification at the location of the cage at 36 months confirmed histological observations. Radiographic, CT scan, MRI, and histological data were consistent for showing progressive resorption of 96/4 PLDLLA, interbody fusion, and bone remodeling, with no significant signs of local intolerance reaction. These results are promising and suggest further development of 96/4 PLDLLA cages. PMID:16736199

  10. Polymerisationseigenschaften von Bulk-Fill Kompositen

    OpenAIRE

    Maier, Eva

    2015-01-01

    Hintergrund und Ziele: Untersuchung der Polymerisationseigenschaften von Bulk-Fill Kompositen bzgl. Konversionsrate (degree of conversion = DC), Vickers-Härte (HV), Polymerisationsschrumpfungsstress (PSS) und Polymerisationsvolumenschrumpfung (PVS) im Vergleich zu konventionellen Kompositen. Material und Methode: Untersucht wurden die Bulk-Fill Komposite Filtek Bulk Fill Flowable (FBF, 3M ESPE, Seefeld), Surefil Smart Dentin Replacement (SDR, Dentsply, Konstanz), Tetric EvoCeram Bulk Fill...

  11. The centrifugal Jahn-Teller effect in rare-earth cage systems

    OpenAIRE

    Amara, Mehdi

    2015-01-01

    The analysis of the properties of rare-earth based materials relies on the Crystalline Electric Field theory. This theory has to be reconsidered in case of cage-type compounds, where the rare-earth ion can substantially depart from its, high symmetry, average position. It is shown that, in case of an orbital degeneracy at the cage center, a specific Jahn-Teller effect develops in the paramagnetic range: at low temperature, the distribution of the magnetic ion spreads inside the cage, the magn...

  12. Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines

    Institute of Scientific and Technical Information of China (English)

    Chariya; Hahnvajanawong; Wongwarut; Boonyanugomol; Tapanawan; Nasomyon; Watcharin; Loilome; Nisana; Namwat; Natthinee; Anantachoke; Wichittra; Tassaneeyakul; Banchob; Sripa; Wises; Namwat; Vichai; Reutrakul

    2010-01-01

    AIM:To investigate the growth inhibitory mechanism of four caged xanthones from Garcinia hanburyi in cholangiocarcinoma(CCA) KKU-100 and KKU-M156 cells.METHODS:Four caged xanthones,selected on the basis of their anticancer potency and chemical structure diversities(i.e.isomorellin,isomorellinol,forbesione and gambogic acid) were used in this study.Growth inhibition of these caged xanthones was determined using the sulforhodamine B assay.Induction of apoptosis was assessed by observing cell morphology,ethidi...

  13. Laying Performance of Wareng Chicken under Free Choice Feeding and Different Cage Density

    OpenAIRE

    S Iskandar

    2011-01-01

    The aim of the experiment was to explore the possibility of using free choice feeding technique under different cage density for unselected native chicken. Eighty hens of laying Wareng chicken were divided into two feeding systems. Half of them were fed complete commercial diet of 17% crude protein, with 2800 kcal ME/kg and the other half were subjected to free choice diet. The diets were in mash form and placed in sufficient feed troughs in front of each cage. Each cage was occupied by four ...

  14. Spiro annulation of cage polycycles via Grignard reaction and ring-closing metathesis as key steps

    Directory of Open Access Journals (Sweden)

    Sambasivarao Kotha

    2015-08-01

    Full Text Available A simple synthetic strategy to C2-symmetric bis-spiro-pyrano cage compound 7 involving ring-closing metathesis is reported. The hexacyclic dione 10 was prepared from simple and readily available starting materials such as 1,4-naphthoquinone and cyclopentadiene. The synthesis of an unprecedented octacyclic cage compound through intramolecular Diels–Alder (DA reaction as a key step is described. The structures of three new cage compounds 7, 12 and 18 were confirmed by single crystal X-ray diffraction studies.

  15. Percutaneous Vertebroplasty in a Broken Vertebral Titanium Implant (Titanium Mesh Cage)

    International Nuclear Information System (INIS)

    We report the case of a percutaneous consolidation of a broken vertebral implant (Surgical Titanium Mesh Implants; DePuy Spine, Raynham, MA, USA) by vertebroplasty. Four years after anterior spondylectomy with cage implantation and stabilization with posterior instrumentation, the patient was admitted for excruciating back pain. Radiographs showed fracture of the cage, screw, and rod. An anterior surgical approach was deemed difficult and a percutaneous injection of polymethyl methacrylate into the cage was performed following posterior instrumentation replacement. This seems to be an interesting alternative to the classical anterior surgical approach, which is often difficult in postoperative conditions

  16. Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE

    DEFF Research Database (Denmark)

    Valen, Eivind; Pascarella, Giovanni; Chalk, Alistair;

    2009-01-01

    given tissue. Here, we present a new method for high-throughput sequencing of 5' cDNA tags-DeepCAGE: merging the Cap Analysis of Gene Expression method with ultra-high-throughput sequence technology. We apply DeepCAGE to characterize 1.4 million sequenced TSS from mouse hippocampus and reveal a wealth...... of novel core promoters that are preferentially used in hippocampus: This is the most comprehensive promoter data set for any tissue to date. Using these data, we present evidence indicating a key role for the Arnt2 transcription factor in hippocampus gene regulation. DeepCAGE can also detect...

  17. Pet Birds. Cages and Practices of Domestication in Eighteenth-Century Paris

    OpenAIRE

    Breittruck, Julia

    2012-01-01

    This paper focuses on the genesis of the »pet making« of birds in eighteenth-century Paris. It examines the ways in which particular cages, and the corresponding imagination and practice of caretaking and domestication, construed birds as »pets.« The status of these animals in either their difference or similarity to »the human« is analyzed by looking at different kinds of bird-caging instructions. First, I found that bird caging developed as a cultural technique of domestication since it org...

  18. Coulombic Fluids Bulk and Interfaces

    CERN Document Server

    Freyland, Werner

    2011-01-01

    Ionic liquids have attracted considerable interest in recent years. In this book the bulk and interfacial physico-chemical characteristics of various fluid systems dominated by Coulomb interactions are treated which includes molten salts, ionic liquids as well as metal-molten salt mixtures and expanded fluid metals. Of particular interest is the comparison of the different systems. Topics in the bulk phase concern the microscopic structure, the phase behaviour and critical phenomena, and the metal-nonmetal transition. Interfacial phenomena include wetting transitions, electrowetting, surface freezing, and the electrified ionic liquid/ electrode interface. With regard to the latter 2D and 3D electrochemical phase formation of metals and semi-conductors on the nanometer scale is described for a number of selected examples. The basic concepts and various experimental methods are introduced making the book suitable for both graduate students and researchers interested in Coulombic fluids.

  19. Storage of molecular hydrogen into leaky clathrate hydrate cages

    International Nuclear Information System (INIS)

    Full text: Efficient storage of hydrogen into compact media is an essential challenge to establish a hydrogen economy. A nanostructured compound made of water and gas molecules, which is called as clathrate hydrate, is one reasonable choice for this important task. Its structure consists of three-dimensional network of hydrogen-bonded water molecules (host cages) and small nonpolar molecules (guests) encaged within this network. The clathrate hydrate medium is chemically durable, environmentally benign, and also free from the necessity of expensive rare metals. Large amount of molecular hydrogen up to 3.8 wt.% was successfully stored into the structure II hydrogen clathrate hydrate (Fd3m space group, lattice constant ∼ 1.7 nm), while it is only synthesized at low temperature and/or high pressure conditions which are not suitable for industrial applications. Required pressure to put significant amount of hydrogen into the hydrate structure is much reducible by blending in additional guest species acting as a hydrate promoter. The promoter molecules added to the system occupy some of the cages to stabilize the hydrate structure at lower pressures, so that the hydrogen storage capacity is partly reduced instead. In addition to the problem of storage capacity, kinetic aspect of hydrogen clathrate hydrate synthesis is also essential for the expected application. Its conventional production scheme was by freezing promoter's solution contacting with pressurized hydrogen gas; it then takes long time for crystal growth. We have established an alternative scheme enabling much faster synthesis (Okuchi et al., Appl. Phys. Lett., 91, 171903, 2007). We found that when hydrogen-free clathrate hydrate powders including a promoter (tetrahydrofuran) was contacted with pressurized hydrogen gas, hydrogen was quickly absorbed into the hydrate medium. We observed the absorption kinetics by nuclear magnetic resonance spectroscopy as a function of hydrogen pressure and temperature. In

  20. M8L12 cubic cages with all facial Δ or facial Λ configuration: effects of surface anions on the occupancy of the cage and anion exchange.

    Science.gov (United States)

    Yang, Jing; Chang, Xiao-Yong; Sham, Kiu-Chor; Yiu, Shek-Man; Kwong, Hoi-Lun; Che, Chi-Ming

    2016-05-21

    M8L12 cubic cages (M = Mn(II), Zn(II) or Cd(II)), with all eight metal ions having all facial Δ or facial Λ configurations and having an encapsulated anion, were prepared by the self-assembly of m-xylene-bridged imidazolyl-imine ligands and MX2 (X = PF6(-), SbF6(-), TfO(-)) salts; the encapsulated anion exchange with different anions (SbF6(-), Tf2N(-), NO3(-), TsO(-)) was studied and the results with NO3(-) and TsO(-) indicate that anions on the cage surfaces affect the encapsulated anion exchange and the occupancy of the cage. PMID:27064122

  1. Bedding disposal cabinet for containment of aerosols generated by animal cage cleaning procedures.

    Science.gov (United States)

    Baldwin, C L; Sabel, F L; Henke, C B

    1976-02-01

    Laboratory tests with aerosolized spores and animal room tests with uranine dye indicate the effectiveness of a prototype bedding disposal cabinet in reducing airborne contamination generated by cage cleaning procedures. PMID:826219

  2. Highly efficient catalysis of the Kemp elimination in the cavity of a cubic coordination cage

    Science.gov (United States)

    Cullen, William; Misuraca, M. Cristina; Hunter, Christopher A.; Williams, Nicholas H.; Ward, Michael D.

    2016-03-01

    The hollow cavities of coordination cages can provide an environment for enzyme-like catalytic reactions of small-molecule guests. Here, we report a new example (catalysis of the Kemp elimination reaction of benzisoxazole with hydroxide to form 2-cyanophenolate) in the cavity of a water-soluble M8L12 coordination cage, with two features of particular interest. First, the rate enhancement is among the largest observed to date: at pD 8.5, the value of kcat/kuncat is 2 × 105, due to the accumulation of a high concentration of partially desolvated hydroxide ions around the bound guest arising from ion-pairing with the 16+ cage. Second, the catalysis is based on two orthogonal interactions: (1) hydrophobic binding of benzisoxazole in the cavity and (2) polar binding of hydroxide ions to sites on the cage surface, both of which were established by competition experiments.

  3. Cooperative Veratryle and Nitroindoline Cages for Two-Photon Uncaging in the NIR.

    Science.gov (United States)

    Cueto Diaz, Eduardo; Picard, Sébastien; Klausen, Maxime; Hugues, Vincent; Pagano, Paolo; Genin, Emilie; Blanchard-Desce, Mireille

    2016-07-25

    Tandem uncaging systems in which a two-photon absorbing module and a cage moiety, linked via a phosphorous clip, that act together by Förster resonance energy transfer (FRET) have been developed. A library of these compounds, using different linkers and cages (7-nitroindolinyl or nitroveratryl) has been synthesized. The investigation of their uncaging and two-photon absorption properties demonstrates the scope and versatility of the engineering strategy towards efficient two-photon cages and reveals surprising cooperative and topological effects. The interactions between the 2PA module and the caging moiety are found to promote cooperative effects on the 2PA response while additional processes that enhance the uncaging efficiency are operative in well-oriented nitroindoline-derived dyads. These synergic effects combine to lead to record two-photon uncaging cross-section values (i.e., up to 20 GM) for uncaging of carboxylic acids. PMID:27346866

  4. The design of a cervical vertebra titanium plate-interbody fusion cage

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Objective: To study the biomechanical feature of a newly designed cervical vertebra internal fixation device and its clinical applications Methods: Some functional spinal units were fixed respectively with titanium plate, fusion cage and new device designed by ourselves, then a controlled biomechanical study including flexion, extension, torsion and lateral bending was performed and the results were analyzed. Results: As to the mechanical performance, fusion cage showed poor performance in extension test and so did the titanium plate in the distortion test. However, the new device showed good performance in every test. Conclusion: Both simple titanium plate fixation and simple fusion cage fixation have biomechanical defaults, but they are complementary. The titanium plate-interbody fusion cage avoids the defaults and has specific advantages.

  5. Feasibility of the sustainable freshwater cage culture in Hungary and Romania

    Directory of Open Access Journals (Sweden)

    Dénes Gál

    2011-12-01

    Full Text Available The intensive cage culture has an adverse effect on the quality of waters due to the highnutrient discharge of intensive fish culture. The combination of the intensive cage and the extensiveaquaculture exploits the advantages of traditional pond farming and intensive fish culture systems.Valuable predatory fish species can be produced in the intensive part of the system, whilst theintegration of an extensive pond as a treatment unit results in decreased nutrient loading to theenvironment and increased nutrient recovery in fish production. The combination of cage and pond fishfarming is a new method for predatory fish production in fishponds. By the exploiting of the traditionalfish ponds with intensive fish production in cages makes possible for the traditional carp farmers toincrease their production capacity, diversify the cultured species and recycle the nutrients within theproduction systems.

  6. Four-dimensional multi-site photolysis of caged neurotransmitters

    Directory of Open Access Journals (Sweden)

    Mary Ann eGo

    2013-12-01

    Full Text Available Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions.

  7. Protein cages, rings and tubes: useful components of future nanodevices?

    Directory of Open Access Journals (Sweden)

    Jonathan G Heddle

    2008-11-01

    Full Text Available Jonathan G HeddleGlobal Edge Institute, Tokyo Institute of Technology, Nagatsuda, Midori-ku, Yokohama Kanagawa, JapanAbstract: There is a great deal of interest in the possibility that complex nanoscale devices can be designed and engineered. Such devices will lead to the development of new materials, electronics and smart drugs. Producing complex nanoscale devices, however will present many challenges and the components of such devices will require a number of special features. Devices will be engineered to incorporate desired functionalities but, because of the difficulties of controlling matter precisely at the nanoscale with current technology, the nanodevice components must self-assemble. In addition, nanocomponents that are to have wide applicability in various devices must have enough flexibility to integrate into a large number of potentially very different environments. These challenges are daunting and complex, and artificial nanodevices have not yet been constructed. However, the existence of nanomachines in nature in the form of proteins (eg, enzymes suggests that they will be possible to produce. As the material from which nature’s nanomachines are made, proteins seem ideal to form the basis of engineered components of such nanodevices. Initially, engineering projects may focus on building blocks such as rings, cages and tubes, examples of which exist in nature and may act as a useful start point for modification and further development. This review focuses on the recent research and possible future development of such protein building blocks.Keywords: bionanotechnology, protein engineering, nanomachine, building-blocks, synthetic biology

  8. Model of a generator end-winding cage

    International Nuclear Information System (INIS)

    This document presents some studies concerning the vibratory characterization of particular structures called: generator end-winding cages. These structures are mainly made up of the endings of armature windings. The question of their good mechanical behaviour is of prime importance, since they are submitted to high electromagnetic efforts during the different electrical ratings encountered during operation. The designer (GEC-Alsthom) and the user (EDF) have both undertaken numerical calculations in order to characterize a given machine, in this case a 600 MW bipolar generator; it appeared interesting to compare such calculations. The models realized respectively by GEC-Alsthom and EDF make use of different techniques and hypotheses. GEC-Alsthom represents the sets of rods and spacers by plates, which properties are determined by a pre-processor. The model is simplified to take into account the existing symmetries. It takes profit of previous experience and aims at a fast utilisation. The EDF model tends to allow a further comprehensive calculation, form the electromagnetic efforts to the determination of local stresses. The whole set of the constituting elements of the structure is modelled by beams, which leads to an important size for the model (21 000 degrees of freedom). The validation performed on the two models has been focused on the comparison between respective results and also with experimental results. Each model provides values for the first eigenfrequencies and the associated modes shapes. (authors). 3 refs., 3 figs., 2 tabs

  9. Four-dimensional multi-site photolysis of caged neurotransmitters

    Science.gov (United States)

    Go, Mary Ann; To, Minh-Son; Stricker, Christian; Redman, Stephen; Bachor, Hans-A.; Stuart, Greg J.; Daria, Vincent R.

    2013-01-01

    Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions. PMID:24348330

  10. Bioresorbable polymers: heading for a new generation of spinal cages.

    Science.gov (United States)

    Wuisman, P I J M; Smit, T H

    2006-02-01

    The use of polymer-based bioresorbable materials is now expanding to the realm of spinal interbody fusion. Bioresorbable polymers have important advantages over metals, because they are temporary, much less stiff, and radiolucent. Most promising is a group of alpha-polyesters, in particular polylactide acids (PLAs). Their biocompatibility is excellent, and they have sufficient stiffness and strength to provide initial and intermediate-term stability required for bone healing. However, polylactides have characteristics that make them vulnerable to complications if not properly controlled. Degradation rate strongly depends on polymer type, impurities, manufacturing process, sterilization, device size, and the local environment. The fact that larger implants degrade faster is contra-intuitive, and should be considered in the design process. Also optimal surgical techniques, such as careful bone bed preparation, are required for a successful application of these materials. The purpose of this paper is to highlight the specific properties of these bioresorbable polymers and to discuss their potential and limitations. This is illustrated with early preclinical and clinical data.Bioresorbable cage technology is just emerging: their time-engineered degradation characteristics allow controlled dynamization in interbody applications, facilitating spinal fusion. Their radiolucency improves image assessment of fusion healing. Acceptance and use of bioresorbable implants may increase as further research and clinical studies report on their safety, efficacy, and proper usage. PMID:16292588

  11. Diaphragm muscle shortening modulates kinematics of lower rib cage in dogs

    OpenAIRE

    Chu, Iris; Fernandez, Cristina; Rodowicz, Kathleen Allen; Lopez, Michael A.; Lu, Raymond; Hubmayr, Rolf D.; Boriek, Aladin M.

    2010-01-01

    We tested the hypothesis that diaphragm muscle shortening modulates volume displacement and kinematics of the lower rib cage in dogs and that posture and mode of ventilation affect such modulation. Radiopaque markers were surgically attached to the lower three ribs of the rib cage and to the midcostal region of the diaphragm in six dogs of ∼8 kg body masses, and the locations of these markers were determined by a biplane fluoroscopy system. Three-dimensional software modeling techniques were ...

  12. Photorelease of GABA with Visible Light Using an Inorganic Caging Group

    OpenAIRE

    Rial Verde, Emiliano M.; Zayat, Leonardo; Etchenique, Roberto; Yuste, Rafael

    2008-01-01

    We describe the selective photorelease of γ-amino butyric acid (GABA) with a novel caged-GABA compound that uses a ruthenium complex as photosensor. This compound (“RuBi-GABA”) can be excited with visible wavelengths, providing greater tissue penetration, less photo-toxicity, and faster photorelease kinetics than currently used UV light-sensitive caged compounds. Using pyramidal neurons from neocortical brain slices, we show that RuBi-GABA uncaging induces GABA-A receptor-mediated responses, ...

  13. Control System for Producing Electricity with Dual Stator Winding Cage-Rotor Induction Generator

    OpenAIRE

    Lucian Nicolae Tutelea; Sorin Ioan Deaconu; Gabriel Nicolae Popa

    2014-01-01

    This paper will present the key design equations and control design model of the Dual Stator Winding Cage-Rotor Induction Generator (DSWIG) to achieve wide-speed-range operation with reduced capacity of the static power controller for low power wind or hydro applications. The proposed induction generator consists of a standard squirrel-cage rotor and a stator with two separate windings wound for a similar number of poles. Moreover, the system control strategy using the stato...

  14. Focusing of high intensity ultrasound through the rib cage using a therapeutic random phased array

    OpenAIRE

    Bobkova, Svetlana; Gavrilov, Leonid; Khokhlova, Vera; Shaw, Adam; Hand, Jeffrey; ,

    2010-01-01

    A method for focusing high intensity ultrasound through a rib cage that aims to minimize heating of the ribs whilst maintaining high intensities at the focus (or foci) is proposed and tested theoretically and experimentally. Two approaches, one based on geometric acoustics and the other accounting for diffraction effects associated with propagation through the rib cage, are investigated theoretically for idealized source conditions. It is shown that for an idealized radiator the diffraction a...

  15. A practical guide to the synthesis of dinitroindolinyl-caged neurotransmitters

    OpenAIRE

    Ellis-Davies, Graham C. R.

    2011-01-01

    This protocol describes a method for efficient chemical synthesis of dinitroindolinyl derivatives of glutamate and gamma-aminobutyric acid. these caged neurotransmitters are currently the most chemically and photochemically efficient probes for two-photon photolysis in living brain slices. the protocol only requires basic organic synthesis equipment, and no silica gel column chromatography or NMR spectroscopy is needed at any stage. Hplc is used to purify the caged transmitters at the end of ...

  16. Late Results of Anterior Cervical Discectomy and Fusion with Interbody Cages

    OpenAIRE

    Dağlı, Murat; Er, Uygur; Şimşek, Serkan; Bavbek, Murad

    2013-01-01

    Study Design Retrospective analysis. Purpose To evaluate the effectiveness of anterior cervical discectomy with fusion for degenerative cervical disc disease. Overview of Literature Anterior spinal surgery originated in the mid-1950s and graft for fusion was also employed. Currently anterior cervical microdiscectomy and fusion with an intervertebral cage is a widely accepted procedure for treatment of cervical disc hernia. Artificial grafts and cages for fusion are preferred because of their ...

  17. Synthesis of Silsesquioxane Cages from Phenyl-cis-tetrol,1,3-Divinyltetraethoxydisiloxane and Cyclopentyl Resins

    Institute of Scientific and Technical Information of China (English)

    LIU Zhi-hua; Alan R. Bassindale; Peter G. Taylor

    2004-01-01

    The synthesis of Ts, T10 and T12 silsesquioxane cages from a range of starting materials: phenyl-cistetrol, 1,3-divinyltetraethoxydisiloxane and cyclopentyl T resins by using tetra n-butylammonium fluoride (TBAF) as the catalyst is described in this paper. The reaction yields obtained via the current route are better compared to those via the literature routes. Some of the cage compounds have been characterized by X-ray crystallography.

  18. Multifunctional photoreactive inorganic cages for three-dimensional holographic data storage.

    Science.gov (United States)

    Lee, Seungwoo; Jeong, Yong-Cheol; Lee, Jihye; Park, Jung-Ki

    2009-10-15

    We demonstrate a holographic photopolymer based on multifunctional photoreactive inorganic cages, polyhedral oligomeric silsesquioxane (POSS). It is shown that a second photopolymerizable monomer, POSS, for the photopolymer, contributes to significantly enhance photosensitivity as well as refractive index modulation (Deltan). We also found that during the formation of holographic gratings, polymerization of POSS could effectively suppress volume shrinkage of photopolymer resin, owing to its filler-strengthening effect of inorganic cages accompanied with interpenetrating effect. PMID:19838237

  19. Economic analysis of the environmental impact on marine cage lobster aquaculture in Vietnam

    OpenAIRE

    Ly, Nguyen Thi Y

    2009-01-01

    In Vietnam, marine cage lobster aquaculture has been expanding significantly over the last years. Besides the economic contribution for locals living in the coastal areas in Central of Vietnam, this industry has created some problems that are relating to the marine environmental protection where trash fish feed is predominant. This paper investigates the environmental impact on cage marine lobster aquaculture in Vietnam by using the Change of Productivity method in which nitrogen releasing fr...

  20. Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation†

    OpenAIRE

    Zhao, Jun; Gover, Tony D; Muralidharan, Sukumaran; Auston, Darryl A.; Weinreich, Daniel; Kao, Joseph P.Y.

    2006-01-01

    Nociceptive neurons in the peripheral nervous system detect noxious stimuli and report the information to the central nervous system. Most nociceptive neurons express the vanilloid receptor, TRPV1, a non-selective cation channel gated by vanilloid ligands such as capsaicin, the pungent essence of chili peppers. Here, we report the synthesis and biological application of two caged vanilloids—biologically inert precursors that, when photolyzed, release bioactive vanilloid ligands. The two caged...

  1. Environmental impact of sea bass cage farming in the north Adriatic Sea

    Directory of Open Access Journals (Sweden)

    Domenico Lanari

    2010-01-01

    Full Text Available The main objective of the research was to reduce the organic and nutrient load under the net pen fish farms. An exper- iment was conducted to study the effects of artificial barriers fixed under a set of sea cages in order to reduce the envi- ronmental impact. The artificial barriers were made of four submerged galvanized steel pipes coated with plastic and placed on the sea floor (10 m depth in the Trieste gulf. The experimental design was as follows: control (C, cages with barriers (B, cages without barriers (WB. Measurements were taken on the surface as well as at 4 and 8m of depth. The trial lasted from the end of June 2000 to December 2001. Water quality parameters were not significantly influenced by the fish cages. Surface samples were characterised by lower levels of salinity and higher levels of oxygen and nitrate compared to those taken at 4 and 8 m. The artificial barriers favoured the establishment of a rich epiphytic fauna that took advantage of the presence of organic matter derived from fish cages. The two species Nucula nucleusand Neanthes caudataand the total bacterial counts were identified as potential indicators of pollution under the fish cage farms.

  2. Titanium Alloy Cage Implantation for the Treatment of Ischemic Necrosis of Femoral Head in Dogs

    Institute of Scientific and Technical Information of China (English)

    Ruiying WANG; Yan GAO; Shuhua YANG; Cao YANG

    2008-01-01

    To study the effect of titanium alloy cage on the treatment of the ischemic necrosis of femoral head in dog, the model of the ischemic necrosis of femoral head was made with the liquid nitrogon in 15 hybrid adult dogs. The titanium alloy cage made of a hollow cylinder was driven into the subchondral bone of necrotic femoral head via central channel. The dogs were divided into 3 groups, each group was sacrificed 3, 6, 12 weeks after the operation respectively. No collapse of femoral head was observed after the operation. The position of the cages was good on radiograph. Microscopically, the cancellous bone of necrotic femoral head rebuilt gradually and grew into cage. After 12 weeks of creeping substitution, the cancellous bone filled up the hollow cavity and holes of the cages. It is concluded that the titanium alloy cage can provide structural support for the subchondral bone and prevent collapse and can be used for the treatment of the ischemic necrosis of femoral head.

  3. Evaluation of caged freshwater mussels as an alternative method for environmental effects monitoring (EEM) studies

    International Nuclear Information System (INIS)

    Results from caged mussel experiments agreed with benthic invertebrate surveys, but not with trends observed for fish. - On three occasions between 1998 and 2000, freshwater mussels were collected by divers in Lake Memphremagog during the spring and transplanted to various locations in the St-Francois River (Quebec, Canada). Mussel growth was monitored by comparing total weight and length at the beginning and end of the exposure period. In 1998, mussels were caged for 60 days at 10 stations, including locations receiving treated effluents from three pulp and paper mills. Overall, there was an apparent trend of increased mussel growth from upstream to downstream along the river. However, mussels caged downstream from the effluent discharge of a bleached kraft pulp and paper mill grew more slowly than those caged immediately upstream in the river. In 1999 and 2000, we further investigated the situation in the vicinity of this bleached kraft mill. The measurements again indicated that growth of mussels in the effluent plume from this mill was reduced in comparison to sites upstream. Overall, in terms of growth, the caged mussels responded both positively and negatively to different environmental conditions. Compared with other monitoring approaches used at these sites during the same period, the caged mussel experiment results were consistent with the trends observed with the benthic invertebrate survey but not with the trends observed for fish

  4. DFT-based inhibitor and promoter selection criteria for pentagonal dodecahedron methane hydrate cage

    Indian Academy of Sciences (India)

    Snehanshu Pal; T K Kundu

    2013-09-01

    Density functional theory (DFT)-based simulations have been performed to provide electronic structure property correlation based reasoning for conceptualizing the effect of encapsulated methane molecule on the formation of methane hydrate cages, the role of methanol and ethylene glycol as inhibitor and the role of tetra-hydro-furan (THF) and cyclopentane as promoter of methane hydrate. Geometry optimization of 512 cage, 51262 cage and 51264 cage with and without encapsulated methane and the cluster of 512 cage with ethylene glycol, methanol, cyclopentane have been performed by density functional theory using B97X-D/6-31++G(d,p) method. Methane hydrate formation inhibition by methanol and ethylene glycol as well as methane hydrate stabilization by cyclopentane and tetrahydrofuran are critically analysed based on the interaction energy, free energy change, dipole moment and infrared frequency calculation. Calculation of free energy change for formation of methane hydrate with/without reagents at various temperature and pressure using optimized structure is reported here. It is observed that hydrogen bond between water molecules of clathrate 512 cages become stronger in the presence of cyclopentane and tetrahydrofuran but weaker/broken in the presence of ethylene glycol and methanol. Simulated results correspond well with experimental findings and can be useful for designing new inhibitor and promoter molecules for gas hydrate formation.

  5. Effects of Metabolic Cage Housing on Rat Behavior and Performance in the Social Interaction Test.

    Science.gov (United States)

    Whittaker, Alexandra L; Lymn, Kerry A; Howarth, Gordon S

    2016-01-01

    Although the metabolic cage is commonly used for housing nonhuman animals in the laboratory, it has been recognized as constituting a unique stressor. Such an environment would be expected to affect behavioral change in animals housed therein. However, few studies have specifically addressed the nature or magnitude of this change. The current study sought to characterize the behavioral time budget of rats in metabolic cage housing in comparison to that of individually housed animals in standard open-top cages. Rats in metabolic cages spent less time moving, manipulating enrichment, and carrying out rearing behaviors, and there was a corresponding shift toward inactivity. In an applied Social Interaction Test, behavioral scoring implied that metabolic cage housing had an anxiogenic effect. In conclusion, metabolic cage housing produces measurable effects on spontaneous and evoked behavior in rats in the laboratory. These behavioral changes may lead to a negative emotional state in these animals, which could have negative welfare consequences. Further research is needed to quantify the existence and magnitude of such an effect on rat well being. PMID:27057787

  6. Diffusive hydrogen inter-cage migration in hydrogen and hydrogen-tetrahydrofuran clathrate hydrates.

    Science.gov (United States)

    Cao, Huayu; English, Niall J; MacElroy, J M D

    2013-03-01

    Classical equilibrium molecular dynamics simulations have been performed to investigate the diffusive properties of inter-cage hydrogen migration in both pure hydrogen and mixed hydrogen-tetrahydrofuran sII hydrates at 0.05 kbar from 200 K and up to 250-260 K. For mixed H2-THF systems in which there is single H2 occupation of the small cage (labelled "1S1L"), we found that no H2 migration occurs. However, for more densely filled H2-THF and pure-H2 systems, in which there is more than single H2 occupation in the small cage, there is an onset of inter-cage H2 migration events from the small cages to neighbouring cavities at around 200 K. The mean square displacements of the hydrogen molecules were fitted to a mathematical model consisting of an anomalous term and a Fickian component, and nonlinear regression fitting was conducted to estimate long-time (inter-cage) diffusivities. An approximate Arrhenius temperature relationship for the diffusion coefficient was examined and an estimation of the hydrogen hopping energy barrier was calculated for each system. PMID:23485313

  7. Bulk metallic glass tube casting

    International Nuclear Information System (INIS)

    Research highlights: → Tubular specimens of Zr55Cu30Al10Ni5 cast in custom arc-melting furnace. → Tilt casting supplemented by suction casting. → Bulk metallic glass formed only with optimized processing parameters. → Fully amorphous tubes with 1.8 mm wall thickness and 25 mm diameter. - Abstract: Tubular bulk metallic glass specimens were produced, using a custom-built combined arc-melting tilt-casting furnace. Zr55Cu30Al10Ni5 tubes with outer diameter of 25 mm and 0.8-3 mm wall thicknesses were cast, with both tilt and suction casting to ensure mold filling. Tilt casting was found to fill one side of the tube mold first, with the rest of the tube circumference filled subsequently by suction casting. Optimized casting parameters were required to fully fill the mold and ensure glass formation. Too small melt mass and too low arc power filled the mold only partially. However, too large melt mass and higher arc power which lead to the best mold filling also lead to partial crystallization. Variations in processing parameters were explored, until a glassy ring with 1.8 mm thickness was produced. Different sections of the as-cast ring were investigated by X-ray diffraction (XRD), differential scanning calorimetry (DSC), and instrumented indentation to ensure amorphous microstructure. Atomic force microscopy (AFM) was used to compare the surface qualities of the first- and last-filled sections. These measurements confirmed the glassy structure of the cast ring, and that, the tilt cast tube section consistently showed better surface quality than the suction cast section. Optimized casting parameters are required to fully realize the potential of directly manufacturing complex shapes out of high-purity bulk metallic glasses by tilt casting.

  8. Bulk Moisture and Salinity Sensor

    Science.gov (United States)

    Nurge, Mark; Monje, Oscar; Prenger, Jessica; Catechis, John

    2013-01-01

    Measurement and feedback control of nutrient solutions in plant root zones is critical to the development of healthy plants in both terrestrial and reduced-gravity environments. In addition to the water content, the amount of fertilizer in the nutrient solution is important to plant health. This typically requires a separate set of sensors to accomplish. A combination bulk moisture and salinity sensor has been designed, built, and tested with different nutrient solutions in several substrates. The substrates include glass beads, a clay-like substrate, and a nutrient-enriched substrate with the presence of plant roots. By measuring two key parameters, the sensor is able to monitor both the volumetric water content and salinity of the nutrient solution in bulk media. Many commercially available moisture sensors are point sensors, making localized measurements over a small volume at the point of insertion. Consequently, they are more prone to suffer from interferences with air bubbles, contact area of media, and root growth. This makes it difficult to get an accurate representation of true moisture content and distribution in the bulk media. Additionally, a network of point sensors is required, increasing the cabling, data acquisition, and calibration requirements. measure the dielectric properties of a material in the annular space of the vessel. Because the pore water in the media often has high salinity, a method to measure the media moisture content and salinity simultaneously was devised. Characterization of the frequency response for capacitance and conductance across the electrodes was completed for 2-mm glass bead media, 1- to 2-mm Turface (a clay like media), and 1- to 2-mm fertilized Turface with the presence of root mass. These measurements were then used to find empirical relationships among capacitance (C), the dissipation factor (D), the volumetric water content, and the pore water salinity.

  9. Gold based bulk metallic glass

    OpenAIRE

    Schroers, Jan; Lohwongwatana, Boonrat; Johnson, William L.; Peker, Atakan

    2005-01-01

    Gold-based bulk metallic glass alloys based on Au-Cu-Si are introduced. The alloys exhibit a gold content comparable to 18-karat gold. They show very low liquidus temperature, large supercooled liquid region, and good processibility. The maximum casting thickness exceeds 5 mm in the best glassformer. Au49Ag5.5Pd2.3Cu26.9Si16.3 has a liquidus temperature of 644 K, a glass transition temperature of 401 K, and a supercooled liquid region of 58 K. The Vickers hardness of the alloys in this system...

  10. Iron - based bulk amorphous alloys

    Directory of Open Access Journals (Sweden)

    R. Babilas

    2010-07-01

    Full Text Available Purpose: The paper presents a structure characterization, thermal and soft magnetic properties analysis of Fe-based bulk amorphous materials in as-cast state and after crystallization process. In addition, the paper gives some brief review about achieving, formation and structure of bulk metallic glasses as a special group of amorphous materials.Design/methodology/approach: The studies were performed on Fe72B20Si4Nb4 metallic glass in form of ribbons and rods. The amorphous structure of tested samples was examined by X-ray diffraction (XRD, transmission electron microscopy (TEM and scanning electron microscopy (SEM methods. The thermal properties of the glassy samples were measured using differential thermal analysis (DTA and differential scanning calorimetry (DSC. The magnetic properties contained initial and maximum magnetic permeability, coercive force and magnetic after-effects measurements were determined by the Maxwell-Wien bridge and VSM methods.Findings: The X-ray diffraction and transmission electron microscopy investigations revealed that the studied as-cast bulk metallic glasses in form of ribbons and rods were amorphous. Two stage crystallization process was observed for studied bulk amorphous alloy. The differences of crystallization temperature between ribbons and rods with chosen thickness are probably caused by different amorphous structures as a result of the different cooling rates in casting process. The SEM images showed that studied fractures could be classified as mixed fractures with indicated two zones contained “river” and “smooth” areas. The changing of chosen soft magnetic properties (μr, Bs, Hc obtained for samples with different thickness is a result of the non-homogenous amorphous structure of tested metallic glasses. The annealing process in temperature range from 373 to 773 K causes structural relaxation of tested amorphous materials, which leads to changes in their physical properties. The qualitative

  11. Osmotic Pressure and Packaging Structure of Caged DNA☆

    OpenAIRE

    Li, Zhidong; Wu, Jianzhong; Wang, Zhen-Gang

    2008-01-01

    We present a theoretical model for aqueous solutions of double-stranded (ds) DNA with explicit consideration of electrostatic interactions, excluded-volume effects, van der Waals attractions, and salt ions. With reasonable parameters estimated from the DNA structure and experimental data for electrolytes, we are able to reproduce the DNA osmotic pressure in the bulk in good agreement with experiment. The predicted DNA osmotic pressure in λ-bacteriophages is found to coincide with that of the ...

  12. Analysis and interpretation of the model of a Faraday cage for electromagnetic compatibility testing

    Directory of Open Access Journals (Sweden)

    Nenad V. Munić

    2014-02-01

    Full Text Available In order to improve the work of the Laboratory for Electromagnetic Compatibility Testing in the Technical Test Center (TTC, we investigated the influence of the Faraday cage on measurement results. The primary goal of this study is the simulation of the fields in the cage, especially around resonant frequencies, in order to be able to predict results of measurements of devices under test in the anechoic chamber or in any other environment. We developed simulation (computer models of the cage step by step, by using the Wipl-D program and by comparing the numerical results with measurements as well as by resolving difficulties due to the complex structure and imperfections of the cage. The subject of this paper is to present these simulation models and the corresponding results of the computations and measurements. Construction of the cage The cage is made of steel plates with the dimensions 1.25 m x 2.5 m. The base of the cage is a square; the footprint interior dimensions are 3.76 m x 3.76 m, and the height is 2.5 m. The cage ceiling is lowered by plasticized aluminum strips. The strips are loosely attached to the carriers which are screwed to the ceiling. The cage has four ventilation openings (two on the ceiling and two on one wall, made of honeycomb waveguide holes. In one corner of the cage, there is a single door with springs made of beryllium bronze. For frequencies of a few tens of MHz, the skin effect is fully developed in the cage walls. By measuring the input impedance of the wire line parallel to a wall of the cage, we calculated the surface losses of the cage plates. In addition, we used a magnetic probe to detect shield discontinuities. We generated a strong current at a frequency of 106 kHz outside the cage and measured the magnetic field inside the cage at the places of cage shield discontinuities. In this paper, we showed the influence of these places on the measurement results, especially on the qualitative and quantitative

  13. Bulk dynamics for interfacial growth models

    OpenAIRE

    López, Cristóbal; Santos, Fernando; Garrido, P. L.

    2000-01-01

    We study the influence of the bulk dynamics of a growing cluster of particles on the properties of its interface. First, we define a general bulk growth model by means of a continuum Master equation for the evolution of the bulk density field. This general model just considers an arbitrary addition of particles (though it can be easily generalized to consider subtraction) with no other physical restriction. The corresponding Langevin equation for this bulk density field is derived where the i...

  14. Biomechanical evaluation of DTRAX® posterior cervical cage stabilization with and without lateral mass fixation

    Science.gov (United States)

    Voronov, Leonard I; Siemionow, Krzysztof B; Havey, Robert M; Carandang, Gerard; Patwardhan, Avinash G

    2016-01-01

    Introduction Lateral mass screw (LMS) fixation with plates or rods is the current standard procedure for posterior cervical fusion. Recently, implants placed between the facet joints have become available as an alternative to LMS or transfacet screws for patients with cervical spondylotic radiculopathy. The purpose of this study was to evaluate the biomechanical stability of the DTRAX® cervical cage for single- and two-level fusion and compare this to the stability achieved with LMS fixation with rods in a two-level construct. Methods Six cadaveric cervical spine (C3–C7) specimens were tested in flexion–extension, lateral bending, and axial rotation to ±1.5 Nm moment without preload (0 N) in the following conditions: 1) intact (C3–C7), 2) LMS and rods at C4–C5 and C5–C6, 3) removal of all rods (LMS retained) and placement of bilateral posterior cages at C5–C6, 4) bilateral posterior cages at C4–C5 and C5–C6 (without LMS and rods), and 5) C4–C5 and C5–C6 bilateral posterior cages at C4–C5 and C5–C6 with rods reinserted. Results Bilateral posterior cervical cages significantly reduced range of motion in all tested directions in both single- and multilevel constructs (P<0.05). Similar stability was achieved with bilateral posterior cages and LMS in a two-level construct: 0.6°±0.3° vs 1.2°±0.4° in flexion–extension (P=0.001), (5.0°±2.6° vs 3.1°±1.3°) in lateral bending (P=0.053), (1.3°±1.0° vs 2.2°±0.9°) in axial rotation (P=0.091) for posterior cages and LMS, respectively. Posterior cages, when placed as an adjunct to LMS, further reduced range of motion in a multilevel construct (P<0.05). Conclusion Bilateral posterior cages provide similar cervical segmental stability compared with a LMS and rod construct and may be an alternative surgical option for select patients. Furthermore, supplementation of a lateral mass construct with posterior cages increases cervical spine stability in single- and multilevel conditions. PMID

  15. Impact of sea waves on underwater fish-breeding cages

    Directory of Open Access Journals (Sweden)

    Pilyaev Sergey Ivanovich

    2014-02-01

    Full Text Available Cultivation of sea objects is of great importance while solving the problems of providing the constantly growing requirements of the national economy with sea products. Cultivation of sea objects uses special hydrobiotechnical constructions. As the practice showed, cultivation of seafood is commercially impossible without solving the questions of calculating and designing such constructions. In special literature these questions are poorly covered or not considered at all. In the article the results of theoretical and pilot studies of waves influence on hydrobiotechnical constructions is provided, in particular on underwater fish-breeding cages.This article offers the theoretical solution to the problem of determining the efforts of the ropes holding the fish tank under wave influences. In order to solve this problem, the equations of hard drives movements were set up and the differential equations of free oscillations of buzz were obtained.When determining the horizontal movements, the four different configurations of connections and the system motion directions in general are possible in case of waveoscillations. Next step is the solution of the differential equations and determination of natural oscillation frequency in the direction of the vertical axis. Defining efforts in the ropes from their own weight (static calculation is self-explanatory, it should be noted that accounting for the weighing influence of water on such structures does not have significant influence.Further the authors defined loading and efforts from the regular waves’ impacts.Modeling of the waves influence on submersible fish tank was carried by Fraud method. The studies were conducted with two models with large and small mesh. The signals of strain gauge sensors were registered by electronic measuring equipment.When comparing the theoretical and experimental data, satisfactory results have been obtained. It was determined that in order to improve the calculation

  16. Calcium Sulfoaluminate Sodalite (Ca 4 Al 6 O 12 SO 4 ) Crystal Structure Evaluation and Bulk Modulus Determination

    KAUST Repository

    Hargis, Craig W.

    2013-12-12

    The predominant phase of calcium sulfoaluminate cement, Ca 4(Al6O12)SO4, was investigated using high-pressure synchrotron X-ray diffraction from ambient pressure to 4.75 GPa. A critical review of the crystal structure of Ca4(Al 6O12)SO4 is presented. Rietveld refinements showed the orthorhombic crystal structure to best match the observed peak intensities and positions for pure Ca4(Al6O 12)SO4. The compressibility of Ca4(Al 6O12)SO4 was studied using cubic, orthorhombic, and tetragonal crystal structures due to the lack of consensus on the actual space group, and all three models provided similar results of 69(6) GPa. With its divalent cage ions, the bulk modulus of Ca4(Al6O 12)SO4 is higher than other sodalites with monovalent cage ions, such as Na8(AlSiO4)6Cl2 or Na8(AlSiO4)6(OH)2·H 2O. Likewise, comparing this study to previous ones shows the lattice compressibility of aluminate sodalites decreases with increasing size of the caged ions. Ca4(Al6O12)SO4 is more compressible than other cement clinker phases such as tricalcium aluminate and less compressible than hydrated cement phases such as ettringite and hemicarboaluminate. © 2013 The American Ceramic Society.

  17. Field cage studies and progressive evaluation of genetically-engineered mosquitoes.

    Directory of Open Access Journals (Sweden)

    Luca Facchinelli

    Full Text Available BACKGROUND: A genetically-engineered strain of the dengue mosquito vector Aedes aegypti, designated OX3604C, was evaluated in large outdoor cage trials for its potential to improve dengue prevention efforts by inducing population suppression. OX3604C is engineered with a repressible genetic construct that causes a female-specific flightless phenotype. Wild-type females that mate with homozygous OX3604C males will not produce reproductive female offspring. Weekly introductions of OX3604C males eliminated all three targeted Ae. aegypti populations after 10-20 weeks in a previous laboratory cage experiment. As part of the phased, progressive evaluation of this technology, we carried out an assessment in large outdoor field enclosures in dengue endemic southern Mexico. METHODOLOGY/PRINCIPAL FINDINGS: OX3604C males were introduced weekly into field cages containing stable target populations, initially at 10:1 ratios. Statistically significant target population decreases were detected in 4 of 5 treatment cages after 17 weeks, but none of the treatment populations were eliminated. Mating competitiveness experiments, carried out to explore the discrepancy between lab and field cage results revealed a maximum mating disadvantage of up 59.1% for OX3604C males, which accounted for a significant part of the 97% fitness cost predicted by a mathematical model to be necessary to produce the field cage results. CONCLUSIONS/SIGNIFICANCE: Our results indicate that OX3604C may not be effective in large-scale releases. A strain with the same transgene that is not encumbered by a large mating disadvantage, however, could have improved prospects for dengue prevention. Insights from large outdoor cage experiments may provide an important part of the progressive, stepwise evaluation of genetically-engineered mosquitoes.

  18. Handling of bulk solids theory and practice

    CERN Document Server

    Shamlou, P A

    1990-01-01

    Handling of Bulk Solids provides a comprehensive discussion of the field of solids flow and handling in the process industries. Presentation of the subject follows classical lines of separate discussions for each topic, so each chapter is self-contained and can be read on its own. Topics discussed include bulk solids flow and handling properties; pressure profiles in bulk solids storage vessels; the design of storage silos for reliable discharge of bulk materials; gravity flow of particulate materials from storage vessels; pneumatic transportation of bulk solids; and the hazards of solid-mater

  19. Avaliação do tratamento da discopatia degenerativa cervical pela artrodese via anterior utilizando placas associadas a cages ou cages em peek isoladamente Evaluación del tratamiento de la enfermedad degenerativa del disco cervical por la artrodesis anterior utilizando placas asociadas con jaulas o jaulas en peec, aisladamente Evaluation of cervical degenerative disc disease treatment by anterior arthrodesis using plates associated with cages or cages in peek alone

    OpenAIRE

    André Rafael Hübner; Marcelo Ribeiro Mendes; Jean Carlo Frigotto Queruz; Jean Marcel Dambrós; Álvaro Diego Heredia Suárez; Leandro de Freitas Spinelli

    2011-01-01

    OBJETIVOS: Avaliar comparativamente o tratamento da discopatia degenerativa cervical por discectomia e artrodese cervical via anterior utilizando placas associadas a cages ou cages em PEEK isoladamente. MÉTODOS: Foi realizado um estudo retrospectivo comparativo entre dois grupos de pacientes operados pela técnica de discectomia e artrodese cervical via anterior. Foram selecionados aleatoriamente 70 pacientes, 35 operados com o método de fixação com placas associadas a cages - denominado Grupo...

  20. Porous Biodegradable Lumbar Interbody Fusion Cage Design and Fabrication Using Integrated Global-Local Topology Optimization With Laser Sintering

    OpenAIRE

    Kang, Heesuk; Hollister, Scott J; La Marca, Frank; Park, Paul; Lin, Chia-Ying

    2013-01-01

    Biodegradable cages have received increasing attention for their use in spinal procedures involving interbody fusion to resolve complications associated with the use of nondegradable cages, such as stress shielding and long-term foreign body reaction. However, the relatively weak initial material strength compared to permanent materials and subsequent reduction due to degradation may be problematic. To design a porous biodegradable interbody fusion cage for a preclinical lar...

  1. Final Report for DUSEL R&D: BetaCage: A Screener of Ultra-Low-Level Radioactive Surface Contamination

    Energy Technology Data Exchange (ETDEWEB)

    Golwala, Sunil R. [California Institute of Technology

    2013-12-20

    The eventual full-size, radiopure BetaCage will be a low-background, atmospheric-pressure neon drift chamber with unprecedented sensitivity to emitters of low-energy electrons and alpha particles. We expect that the prototype BetaCage already developed will be an excellent screener of alpha particles. Both the prototype and final BetaCage will provide new infrastructure for rare-event science.

  2. Effect of multilevel laboratory rat caging system on the well-being of the singly-housed Sprague Dawley rat.

    Science.gov (United States)

    Wheeler, R R; Swan, M P; Hickman, D L

    2015-01-01

    Current regulations emphasize that good husbandry practices allow animals to engage in species appropriate postural adjustments without touching the enclosure walls. This study evaluated the well-being of rats housed in a commercially available multilevel rat caging system, with or without access to the upper level of the caging. The evaluation methodologies included assessment of behavioral observations in the home cage, physiological assessment of metabolism and immune function, and determination of the affective state using a spatial cognitive bias assay. The study determined that rats that were provided access to the full multilevel cage during testing after initial restriction to the lower level of the cage demonstrated behavioral changes consistent with a positive affective state, while those with no changes to their housing situation had no significant differences in their affective states. Rats that were consistently housed with access restricted to the lower level of the cage exhibited a tendency to increased neutrophil:lymphocyte ratios as compared with those provided with access to all levels of the multilevel cage. There were no differences in body weight demonstrated between the experimental groups. Overall use of the cage space, as documented through analysis of behavioral observations in the home cage, demonstrated no significant differences in preferred location in the cage during the light or dark cycles, though rats with access to both levels of the cage were significantly more active during the light cycle. The results of this study suggest that the use of a multilevel caging system may improve the well-being of rats used in research. PMID:25117586

  3. Gold based bulk metallic glass

    Science.gov (United States)

    Schroers, Jan; Lohwongwatana, Boonrat; Johnson, William L.; Peker, Atakan

    2005-08-01

    Gold-based bulk metallic glass alloys based on Au-Cu-Si are introduced. The alloys exhibit a gold content comparable to 18-karat gold. They show very low liquidus temperature, large supercooled liquid region, and good processibility. The maximum casting thickness exceeds 5mm in the best glassformer. Au49Ag5.5Pd2.3Cu26.9Si16.3 has a liquidus temperature of 644K, a glass transition temperature of 401K, and a supercooled liquid region of 58K. The Vickers hardness of the alloys in this system is ˜350Hv, twice that of conventional 18-karat crystalline gold alloys. This combination of properties makes the alloys attractive for many applications including electronic, medical, dental, surface coating, and jewelry.

  4. Gold based bulk metallic glass

    International Nuclear Information System (INIS)

    Gold-based bulk metallic glass alloys based on Au-Cu-Si are introduced. The alloys exhibit a gold content comparable to 18-karat gold. They show very low liquidus temperature, large supercooled liquid region, and good processibility. The maximum casting thickness exceeds 5 mm in the best glassformer. Au49Ag5.5Pd2.3Cu26.9Si16.3 has a liquidus temperature of 644 K, a glass transition temperature of 401 K, and a supercooled liquid region of 58 K. The Vickers hardness of the alloys in this system is ∼350 Hv, twice that of conventional 18-karat crystalline gold alloys. This combination of properties makes the alloys attractive for many applications including electronic, medical, dental, surface coating, and jewelry

  5. Bulk analysis using nuclear techniques

    International Nuclear Information System (INIS)

    Bulk analysis techniques developed for the mining industry are reviewed. Using penetrating neutron and #betta#-radiations, measurements are obtained directly from a large volume of sample (3-30 kg) #betta#-techniques were used to determine the grade of iron ore and to detect shale on conveyor belts. Thermal neutron irradiation was developed for the simultaneous determination of iron and aluminium in iron ore on a conveyor belt. Thermal-neutron activation analysis includes the determination of alumina in bauxite, and manganese and alumina in manganese ore. Fast neutron activation analysis is used to determine silicon in iron ores, and alumina and silica in bauxite. Fast and thermal neutron activation has been used to determine the soil in shredded sugar cane. (U.K.)

  6. Isotopic signatures by bulk analyses

    International Nuclear Information System (INIS)

    Los Alamos National Laboratory has developed a series of measurement techniques for identification of nuclear signatures by analyzing bulk samples. Two specific applications for isotopic fingerprinting to identify the origin of anthropogenic radioactivity in bulk samples are presented. The first example is the analyses of environmental samples collected in the US Arctic to determine the impact of dumping of radionuclides in this polar region. Analyses of sediment and biota samples indicate that for the areas sampled the anthropogenic radionuclide content of sediments was predominantly the result of the deposition of global fallout. The anthropogenic radionuclide concentrations in fish, birds and mammals were very low. It can be surmised that marine food chains are presently not significantly affected. The second example is isotopic fingerprinting of water and sediment samples from the Rocky Flats Facility (RFP). The largest source of anthropogenic radioactivity presently affecting surface-waters at RFP is the sediments that are currently residing in the holding ponds. One gram of sediment from a holding pond contains approximately 50 times more plutonium than 1 liter of water from the pond. Essentially 100% of the uranium in Ponds A-1 and A-2 originated as depleted uranium. The largest source of radioactivity in the terminal Ponds A-4, B-5 and C-2 was naturally occurring uranium and its decay product radium. The uranium concentrations in the waters collected from the terminal ponds contained 0.05% or less of the interim standard calculated derived concentration guide for uranium in waters available to the public. All of the radioactivity observed in soil, sediment and water samples collected at RFP was naturally occurring, the result of processes at RFP or the result of global fallout. No extraneous anthropogenic alpha, beta or gamma activities were detected. The plutonium concentrations in Pond C-2 appear to vary seasonally

  7. Guidelines for Measuring Bulk Density of Soil

    International Nuclear Information System (INIS)

    Bulk density is defined as the dry weight of soil per unit volume of undisturbed soil. • Bulk density can be used to give an indication of the porosity and structure of the soil influencing O2 and H2O movement in the soil. • Soils with a bulk density higher than 1.6 g/cm3 may restrict root development. • Bulk density is also a measurement of the degree of compaction of the soil. • Bulk density increases with compaction and tends to increase with soil depth. • Sandy soils tend to have higher bulk density (1.4-1.5 g/cm3) than clay soils (1.2-1/3g/cm3). The measurement of soil bulk density is carried out by collecting undisturbed soil samples through inserting metal rings (with a known volume) into the soil, and determining the weight of the collected soil after drying

  8. Biomechanical evaluation of immediate stability with rectangular versus cylindrical interbody cages in stabilization of the lumbar spine

    Directory of Open Access Journals (Sweden)

    Webb John K

    2002-10-01

    Full Text Available Abstract Background Recent cadaver studies show stability against axial rotation with a cylindrical cage is marginally superior to a rectangular cage. The purpose of this biomechanical study in cadaver spine was to evaluate the stability of a new rectangular titanium cage design, which has teeth similar to the threads of cylindrical cages to engage the endplates. Methods Ten motion segments (five L2-3, five L4-5 were tested. From each cadaver spine, one motion segment was fixed with a pair of cylindrical cages (BAK, Sulzer Medica and the other with paired rectangular cages (Rotafix, Corin Spinal. Each specimen was tested in an unconstrained state, after cage introduction and after additional posterior translaminar screw fixation. The range of motion (ROM in flexion-extension, lateral bending, and rotation was tested in a materials testing machine, with +/- 5 Nm cyclical load over 10 sec per cycle; data from the third cycle was captured for analysis. Results ROM in all directions was significantly reduced (p Conclusions There was no significant difference in immediate stability in any direction between the threaded cylindrical cage and the new design of the rectangular cage with endplate teeth.

  9. Detection of early behavioral markers of Huntington's disease in R6/2 mice employing an automated social home cage

    DEFF Research Database (Denmark)

    Rudenko, Olga; Tkach, Vadim; Berezin, Vladimir;

    2009-01-01

    developed behavior screening system, the IntelliCage, allows automated testing of mouse behavior in the home cage employing individual recognition of animals living in social groups. The present study validates the ability of the IntelliCage system to detect behavioral and cognitive dysfunction in R6/2 mice......, an established transgenic model of HD. The results indicate that the IntelliCage is a reliable system for recording exploratory activity, drinking behavior, circadian rhythm, spatial preference, and cognition in mice during prolonged periods of assessment. The system detected early dysfunctional...

  10. John Cage y su influencia en la obra del video artista Nam June Paik

    Directory of Open Access Journals (Sweden)

    Sarriugarte Gómez, Íñigo

    2009-12-01

    Full Text Available In 1958, the Korean artist Nam June Paik (*1932; †2006 meets in Germany John Cage (*1912; †1992, avant-garde musician, who was deeply interested in the Zen Buddhism. The meeting with Cage was vital, because the North American composer will convince him to orient his career towards the artistic avant-garde, giving up his facet like classic pianist. The philosophy of Cage is refl ected in compositions like “4’ 33’’, from 1952, where the spectator doesn’t listen the sound of the piano, because this isn’t played, but he listens a silence that is interrupted by the environmental sound. There are several versions of this piece, marking the silences by means of processes at random with the “I Ching”. In this sense, the silence used by John Cage is related to the vacuity of the Zen Buddhism. Also, Paik makes use of silence in numerous works, like “1963 TV Clock”, where 24 colour television sets are manipulated, feeling at the same time the silence, interrupted again by the own momentary circumstances of the spectator. This same infl uence of the Zen Buddhism in the music of Cage is observed when argues that the music composed of melodies has the same value than the sound understood by us like noises. This aspect, among others, infl uenced to Paik, whose video images are defi ned like attributes of traditional works that don’t impress to the audience, but they suggest variable conditions. Some of his works related to Cage’s philosophy have been “Hommage à John Cage” from 1959; “Study for pianoforte” from 1960; and “Global Grove” from 1973, where Paik uses as a collage the images of his avant-garde collaborators John Cage, Allen Ginsberg and Merce Cunningham.

    En 1958, el artista coreano Nam June Paik (*1932; †2006 conoce en Alemania a John Cage (*1912; †1992, músico vanguardista, quien estaba profundamente interesado en el budismo zen. Su encuentro con Cage fue vital, ya que el compositor

  11. DNA damage in caged Gammarus fossarum amphipods: A tool for freshwater genotoxicity assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lacaze, Emilie [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Devaux, Alain [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Mons, Raphael [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Bony, Sylvie [Universite de Lyon, INRA-ENTPE, Laboratoire des Sciences de l' Environnement, rue Maurice Audin, Vaulx en Velin F-69518 (France); Garric, Jeanne [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France); Geffard, Alain [EA 2069 URVVC-SE, Laboratoire d' Eco-Toxicologie, UFR Sciences, Moulin de la Housse, BP 1039, 51687 Reims Cedex 2 (France); Geffard, Olivier, E-mail: olivier.geffard@cemagref.fr [Cemagref, Unite de Recherche des Milieux Aquatiques, (UR MALY), 3 bis quai Chauveau, 69336 Lyon, Cedex 9 (France)

    2011-06-15

    The aim of this study was to propose a tool for freshwater environmental genotoxicity assessment using Gammarus fossarum, a high ecologically relevant species. In a first part, gammarids were caged upstream and downstream wastewater treatment plant effluent output. The sensitivity of genotoxic responses of haemocytes, oocytes and spermatozoa was compared using the Comet assay. Spermatozoa appeared to be the most sensitive, suitable and relevant cell type for genotoxicity risk assessment. In a second part, a watershed-scale study was conducted over 2 years to evaluate the applicability of our caging procedure. The genotoxic impact of a contamination was followed, taking into account seasonal variability. DNA damage in spermatozoa exhibited low basal level and low variability in control upstream sites, providing a reliable discrimination of polluted sites. Finally, DNA damage in caged G. fossarum has been proved to be a sensitive and reproducible tool for freshwater genotoxicity assessment. - Highlights: > Two different contamination contexts: WWTP effluents and polymetallic contamination. > DNA damage in caged Gammarus fossarum is a sensitive tool for freshwater quality assessment. > Spermatozoa is the most relevant cell type for biomonitoring freshwater genotoxicity. > Combining biomarker responses with analytical chemistry provides rich ecotoxicological information. - We propose an approach to assess freshwater genotoxicity in the field based on caged Gammarus fossarum (Crustacea, amphipoda).

  12. RESULTS OF THE USE OF PEEK CAGES IN THE TREATMENT OF BASILAR INVAGINATION BY GOEL TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Carelli Teixeira da Silva

    2016-03-01

    Full Text Available ABSTRACT Objective: Analysis of the use of polyetheretherketone (PEEK cages for atlantoaxial facet realignment and distraction for treatment of basilar invagination by Goel technique. Method: Retrospective descriptive statistical analysis of the neurological status, pain, presence of subsidence and bone fusion with the use of PEEK cages in 8 atlantoaxial joints of 4 patients with basilar invagination. All patients were treated with atlantoaxial facet distraction and realignment and subsequent arthrodesis C1-C2 by the technique of Goel modified by the use of PEEK cage. Results: All patients showed improvement in Nurick neurological assessment scale and Visual Analogue Scale (VAS of pain. There were no cases of subsidence, migration, or damage to the vertebral artery during the insertion of the cage. All joints evolved with bone fusion, assessed by dynamic radiographs, and computed tomography. Two patients developed neuropathic pain in dermatome of C2 and one patient had unilateral vertebral artery injury during C2 instrumentation treated with insertion of pedicle screw to control the bleeding. Conclusion: The results of the treatment of basilar invagination by the Goel technique with the use of PEEK cages shown to be effective and safe although further studies are needed to confirm this use.

  13. Numerical Analysis of Hydrodynamic Behaviors of Two Net Cages with Grid Mooring System Under Wave Action

    Institute of Scientific and Technical Information of China (English)

    CHEN Chang-ping; ZHAO Yun-peng; LI Yu-cheng; DONG Guo-hai; ZHENG Yan-na

    2012-01-01

    Based on rigid kinematics theory and lumped mass method,a mathematical model of the two net cages of grid mooring system under waves is developed.In order to verify the numerical model,a series of physical model tests have been carried out.According to the comparisons between the simulated and the experimental results,it can be found that the simulated and the experimental results agree well in each wave condition.Then,the forces on the mooring lines and the floating collar movement are calculated under different wave conditions.Numerical results show that under the same condition,the forces on the bridle ropes are the largest,followed by forces on the main ropes and the grid ropes.The horizontal and the vertical float collar motion amplitudes increase with the increase of wave height,while the relationship of the horizontal motion amplitude and the wave period is indistinct.The vertical motion amplitude of the two cages is almost the same,while on the respect of horizontal motion amplitude,cage B (behind cage A,as shown in Fig.4) moves much farther than cage A under the same wave condition.The inclination angle of the floating system both in clockwise alongy axis and the counter one enlarges a little with the increase of wave height.

  14. Dynamic behavior and deformation analysis of the fish cage system using mass-spring model

    Science.gov (United States)

    Lee, Chun Woo; Lee, Jihoon; Park, Subong

    2015-06-01

    Fish cage systems are influenced by various oceanic conditions, and the movements and deformation of the system by the external forces can affect the safety of the system itself, as well as the species of fish being cultivated. Structural durability of the system against environmental factors has been major concern for the marine aquaculture system. In this research, a mathematical model and a simulation method were presented for analyzing the performance of the large-scale fish cage system influenced by current and waves. The cage system consisted of netting, mooring ropes, floats, sinkers and floating collar. All the elements were modeled by use of the mass-spring model. The structures were divided into finite elements and mass points were placed at the mid-point of each element, and mass points were connected by springs without mass. Each mass point was applied to external and internal forces, and total force was calculated in every integration step. The computation method was applied to the dynamic simulation of the actual fish cage systems rigged with synthetic fiber and copper wire simultaneously influenced by current and waves. Here, we also tried to find a relevant ratio between buoyancy and sinking force of the fish cages. The simulation results provide improved understanding of the behavior of the structure and valuable information concerning optimum ratio of the buoyancy to sinking force according to current speeds.

  15. Growth of conformal graphene cages on micrometre-sized silicon particles as stable battery anodes

    Science.gov (United States)

    Li, Yuzhang; Yan, Kai; Lee, Hyun-Wook; Lu, Zhenda; Liu, Nian; Cui, Yi

    2016-02-01

    Nanostructuring has been shown to be fruitful in addressing the problems of high-capacity Si anodes. However, issues with the high cost and poor Coulombic efficiencies of nanostructured Si still need to be resolved. Si microparticles are a low-cost alternative but, unlike Si nanoparticles, suffer from unavoidable particle fracture during electrochemical cycling, thus making stable cycling in a real battery impractical. Here we introduce a method to encapsulate Si microparticles (˜1-3 µm) using conformally synthesized cages of multilayered graphene. The graphene cage acts as a mechanically strong and flexible buffer during deep galvanostatic cycling, allowing the microparticles to expand and fracture within the cage while retaining electrical connectivity on both the particle and electrode level. Furthermore, the chemically inert graphene cage forms a stable solid electrolyte interface, minimizing irreversible consumption of lithium ions and rapidly increasing the Coulombic efficiency in the early cycles. We show that even in a full-cell electrochemical test, for which the requirements of stable cycling are stringent, stable cycling (100 cycles; 90% capacity retention) is achieved with the graphene-caged Si microparticles.

  16. Hydrodynamic coefficients of a simplified floating system of gravity cage in waves

    Institute of Scientific and Technical Information of China (English)

    Chang-wen WU; Fu-kun GUI; Yu-cheng LI; Wei-huan FANG

    2008-01-01

    Numerical simulation and experimental tests were carried out to examine the hydrodynamic behaviors of a double-column floating system of gravity cage under wave conditions. A floating system of gravity cage can be treated as a small-sized floating structure when compared with the wavelengths. The main problem in calculating the wave loads on the small-sized floating structure is to obtain the reasonable force coefficients, which may differ from a submerged structure. In this paper, the floating system of gravity cage is simplified to a 2D problem, where the floating system is set symmetrically under wave conditions. The motion equations were deduced under wave conditions and a specific method was proposed to resolve the problem of wave forces acting on a small-sized floating system of gravity cage at water surface. Results of the numerical method were compared with those from model tests and the hydrodynamic coefficients Cn and C?were studied. It is found that Cn ranges from 0.6 to 1.0 while C?is between 0.4 and 0.6 in this study. The results are useful for research on the hydrodynamic behavior of the deep-water gravity sea cages.

  17. Relative effects of nutrient emission from intensive cage aquaculture on the semiarid reservoir water quality.

    Science.gov (United States)

    Molisani, Mauricio Mussi; do Monte, Thiago Maia; Vasconcellos, George Harrison; de Souza Barroso, Hortência; Moreira, Maria Odete Parente; Becker, Helena; de Rezende, Carlos Eduardo; Franco, Marcos Alberto Lima; de Farias, Eduardo Guilherme Gentil; de Camargo, Plínio Barbosa

    2015-11-01

    The effects of cage aquaculture on freshwater ecosystems are determined by multiple farming and environmental variables, and thus, the assessment of a wide range of abiotic and biotic variables enables better understanding of the impacts generated by this nutrient source. This study was carried out at Castanhão reservoir located in the State of Ceará, which is the largest Brazilian producer of Nile tilapia in cage systems, wherein about 8000 reservoirs provide a vast area to expand not only this important socio-economic but also pollution-prone activity. Nutrient mass budget, water quality monitoring, hydrodynamic characterization, and elemental/stable isotopic composition of end-member products were measured in cage aquaculture and other reservoir areas in order to determine the relative effects on reservoir conditions. Nutrient budgets showed that 34% of the artificial feed was lost to the water column but water quality monitoring and isotopic composition analysis suggested that the cages were not extensively impacting the water quality probably because of the physiographic and hydrodynamic features of the cage site. PMID:26502728

  18. Cage rattling does not correlate with the local geometry in molecular liquids

    CERN Document Server

    Bernini, S; Leporini, D

    2016-01-01

    Molecular-dynamics simulations of a liquid of short linear molecules have been performed to investigate the correlation between the particle dynamics in the cage of the neighbors and the local geometry. The latter is characterized in terms of the size and the asphericity of the Voronoi polyhedra. The correlation is found to be poor. In particular, in spite of the different Voronoi volume around the end and the inner monomers of a molecule, all the monomers exhibit coinciding displacement distribution when they are caged (as well as at longer times during the structural relaxation). It is concluded that the fast dynamics during the cage trapping is a non-local collective process involving monomers beyond the nearest neighbours.

  19. A quadrupole/time-of-flight mass spectrometry study of Trp-cage's conformation.

    Science.gov (United States)

    Lin, Mingxiang; Ahmed, Zeeshan; Taormina, Christopher R; Somayajula, Kasi V

    2007-02-01

    Trp-cage is a synthetic 20-residue miniprotein that uses tertiary contacts to stabilize its native conformation. NMR, circular dichroism (CD), and UV-resonance Raman spectroscopy were used to probe its energy landscape. In this quadrupole/time-of-flight study, electrospray ionization charge state distribution (CSD) and solution-phase H/D exchange are used to probe Trp-cage's tertiary structure. The CSDs of Trp-cage and its mutant provide spectra showing a pH-dependent conformation change. Solution-phase H/D exchange in 30% deuterated trifluoroethanol solution of the wild type shows increased protection of one labile hydrogen in the native state. Together, CSDs and solution-phase H/D exchange are demonstrated to constitute a simple but effective means to follow conformation changes in a small tertiary protein. PMID:17067814

  20. Three-Dimensional Porous Metal-Metalloporphyrin Framework Consisting of Nanoscopic Polyhedral Cages

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xi-Sen; Meng, Le; Cheng, Qigan; Kim, Chungsik; Wojtas, Lukasz; Chrzanowski, Matthew; Chen, Yu-Sheng; Zhang, X Peter; Ma, Shengqian [USF; (UC)

    2012-02-07

    An unprecedented nanoscopic polyhedral cage-containing metal-metalloporphyrin framework, MMPF-1, has been constructed from a custom-designed porphyrin ligand, 5,15-bis(3,5-dicarboxyphenyl)porphine, that links Cu2(carboxylate)4 moieties. A high density of 16 open copper sites confined within a nanoscopic polyhedral cage has been achieved, and the packing of the porphyrin cages via an 'ABAB' pattern affords MMPF-1 ultramicropores which render it selective toward adsorption of H2 and O2 over N2, and CO2 over CH4.

  1. Mediterranean fruit fly: interference of oviposition by radiation-sterilized females in field cages

    International Nuclear Information System (INIS)

    In experiments between April and September 1984, the behaviour of nonirradiated and radiation-sterilized laboratory-adapted adults of the tephritid Ceratitis capitata was observed on apples hung on guava trees in outdoor cages in Hawaii. The numbers of nonirradiated females observed resting on fruit were reduced several times by the presence of irradiated females, either alone or with irradiated males, but not by irradiated males alone. Similarly, the number of nonirradiated females observed ovipositing and the duration of oviposition was reduced by the presence of irradiated females. In control cages (all nonirradiated flies), the duration of oviposition by females averaged 255.9±15.0 s on fruit, while most of nonirradiated and irradiated females in the mixed (treatment) cage averaged 157±19.8 s and 77.5±7.5 s on fruit, resp. Irradiated females behaved skittishly on fruit and frequently engaged in physical encounters with other flies

  2. Design Concepts of Polycarbonate-Based Intervertebral Lumbar Cages: Finite Element Analysis and Compression Testing.

    Science.gov (United States)

    Figueroa-Cavazos, J Obedt; Flores-Villalba, Eduardo; Diaz-Elizondo, José A; Martínez-Romero, Oscar; Rodríguez, Ciro A; Siller, Héctor R

    2016-01-01

    This work explores the viability of 3D printed intervertebral lumbar cages based on biocompatible polycarbonate (PC-ISO® material). Several design concepts are proposed for the generation of patient-specific intervertebral lumbar cages. The 3D printed material achieved compressive yield strength of 55 MPa under a specific combination of manufacturing parameters. The literature recommends a reference load of 4,000 N for design of intervertebral lumbar cages. Under compression testing conditions, the proposed design concepts withstand between 7,500 and 10,000 N of load before showing yielding. Although some stress concentration regions were found during analysis, the overall viability of the proposed design concepts was validated. PMID:27578960

  3. Environmental enrichment and development of cage stereotypy in Orange-winged Amazon parrots (Amazona amazonica).

    Science.gov (United States)

    Meehan, C L; Garner, J P; Mench, J A

    2004-05-01

    Stereotypies are abnormal repetitive behaviors that often develop in animals housed in impoverished environments. Stereotypy represents the interaction of several complex developmental phenomena. To characterize the temporal nature of stereotypy increase (escalation) and decrease (attenuation), we monitored changes in stereotypy performance in young Orange-winged Amazon parrots reared either in barren cages or cages provided with enrichments designed to facilitate foraging and locomotion. Unenriched parrots developed significantly more stereotypy than enriched parrots, and the mean time to stereotypy onset and the rate and magnitude of stereotypy increase also differed between the two groups. We then provided enrichment to the birds that had been reared in the barren cages. Following a 4-week delay, stereotypy was significantly reduced. These results show that stereotypy can be both prevented and reversed with appropriate environmental modification and illustrate how studying this behavior at many points over time can provide insights into its ontogeny. PMID:15103731

  4. Equilibrium simulation of trp-cage in the presence of protein crowders

    Science.gov (United States)

    Bille, Anna; Linse, Björn; Mohanty, Sandipan; Irbäck, Anders

    2015-11-01

    While steric crowders tend to stabilize globular proteins, it has been found that protein crowders can have an either stabilizing or destabilizing effect, where a destabilization may arise from nonspecific attractive interactions between the test protein and the crowders. Here, we use Monte Carlo replica-exchange methods to explore the equilibrium behavior of the miniprotein trp-cage in the presence of protein crowders. Our results suggest that the surrounding crowders prevent trp-cage from adopting its global native fold, while giving rise to a stabilization of its main secondary-structure element, an α-helix. With the crowding agent used (bovine pancreatic trypsin inhibitor), the trp-cage-crowder interactions are found to be specific, involving a few key residues, most of which are prolines. The effects of these crowders are contrasted with those of hard-sphere crowders.

  5. Self-assembly of three-legged patchy particles into polyhedral cages

    International Nuclear Information System (INIS)

    The self-assembly of rigid three-legged building blocks into polyhedral cages is investigated by patchy particle simulations. A four-site anisotropic interaction potential is introduced to make pairs of overlapping legs bind in an anti-parallel fashion, thereby forming the edges of a polyhedron of pentagons and hexagons. A torsional potential, reflecting an asymmetry or polarity in the legs' binding potential, proves crucial for the successful formation of closed fullerene-like cages. Self-assembly proceeds by a nucleation-and-growth mechanism, with a high success rate of cage closure. The size distribution of the self-assembled buckyballs is largely determined by the pucker angle of the particle. Nature explores a similar building block, the clathrin triskelion, to regulate vesicle formation at the cell membrane during endocytosis.

  6. Effect of Cage Space on Behavior and Reproduction in Crl:CD(SD) and BN/Crl Laboratory Rats.

    Science.gov (United States)

    Gaskill, Brianna N; Pritchett-Corning, Kathleen R

    2015-09-01

    The 2011 Guide for the Care and Use of Laboratory Animals contains recommendations regarding the amount of cage space for mothers with litters. Literature on cage-space use in breeding rats is sparse. We hypothesized that, if present, differences in behavior and reproduction would be detected between the smallest and largest cages tested. BN/Crl and Crl:CD(SD) rats were assigned to a cage treatment (580 cm(2), 758 cm(2), 903 cm(2), or 1355 cm(2)) and breeding configuration (single: male removed after birth of pups; pair: 1 male, 1 female) in a factorial design for 12 wk. All cages received 20 to 25 g of nesting material, and nests were scored weekly. Pups were weaned, sexed, and weighed between postnatal days 18 and 26. Adult behavior and location in the cage were videorecorded by scan-sampling on the litter's postnatal days 0 through 8 and 14 through 21. Press posture in adults and play behavior in pups were recorded according to a 1-0 sampling method. Differences in reproductive parameters were limited to expected differences related to rat genetic background and weaning weight in pups, which was lowest in the pair-bred CD rats in the smallest cages. Press posture in adults in the smaller cages increased as the pups became mobile. Pair-housed outbred rats in the smallest commercially available cage we tested showed behavioral changes and a lower pup weaning weight. Both laboratory animal scientists and caging manufacturers should address the challenge of providing more biologically relevant cage complexity rather than merely increasing floor space. PMID:26424247

  7. Application of carbon cage (Brantigan) to lumber vertebra diseases. The examination by MRI

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Masato; Nakahara, Shinnosuke; Suenaga, Atsushi; Yamauchi, Taro [Okayama National Hospital (Japan)

    1997-12-01

    Recently several kinds of interlumber spacers have been used for the posterior lumber interbody fusion (PLIF). We have used Brantigan I/F cage (carbon cage) for PLIF. Here we report the results of PLIF and the postoperative MRI. We examined 10 patients (9 men and 10 women) who underwent carbon cage-used PLIF. Patients at surgery were aged from 36 to 77 years (average 61 years). The postoperative observation periods were from 6 months to 17 months (mean 8.2 months). Diseases contained 12 of lumber degenerative sliding disease, 2 of lumber-spine separate disease and 5 of lumber spine stricture complicating the unstable lumber vertebra. We observed synostosis in all cases, and we obtained the improvement rate by JOA score of 71.4%. There was no complications during surgery, except one case of transient neuroparalysis by postoperative hematoma. The carbon cage-used PLIF was effective to minimize sampling of autologous bones and to prevent the crush of bone grafts. MRI was quite effective to evaluate the position of the carbon cage and to judge synostosis. Using MRI we could judge synostosis by the contrast of grafted bones at only 3 months after surgery. The carbon cage transmits X-ray, which makes it easy to judge synostosis. It has the open window to graft autologous bones and the elasticity almost similar to the cortical bone. On the other hand it has some disadvantages; the difficulty to determine the position by the X-ray images, the biological safety, etc. (K.H.)

  8. Agricultural wetlands as potential hotspots for mercury bioaccumulation: Experimental evidence using caged fish

    Science.gov (United States)

    Ackerman, J.T.; Eagles-Smith, C. A.

    2010-01-01

    Wetlands provide numerous ecosystem services, but also can be sources of methylmercury (MeHg) production and export. Rice agricultural wetlands in particular may be important sites for MeHg bioaccumulation due to their worldwide ubiquity, periodic flooding schedules, and high use by wildlife. We assessed MeHg bioaccumulation within agricultural and perennial wetlands common to California's Central Valley during summer, when the majority of wetland habitats are shallowly flooded rice fields. We introduced caged western mosquitofish (Gambusia affinis) within white rice (Oryza sativa), wild rice (Zizania palustris), and permanent wetlands at water inlets, centers, and outlets. Total mercury (THg) concentrations and body burdens in caged mosquitofish increased rapidly, exceeding baseline values at introduction by 135% to 1197% and 29% to 1566% among sites, respectively, after only 60 days. Mercury bioaccumulation in caged mosquitofish was greater in rice fields than in permanent wetlands, with THg concentrations at wetland outlets increasing by 12.1, 5.8, and 2.9 times over initial concentrations in white rice, wild rice, and permanent wetlands, respectively. In fact, mosquitofish caged at white rice outlets accumulated 721 ng Hg/fish in just 60 days. Mercury in wild mosquito fish and Mississippi silversides (Menidia audens) concurrently sampled at wetland outlets also were greater in white rice and wild rice than permanent wetlands. Within wetlands, THg concentrations and body burdens of both caged and wild fish increased from water inlets to outlets in white rice fields, and tended to not vary among sites in permanent wetlands. Fish THg concentrations in agricultural wetlands were high, exceeding 0.2 ??g/g ww in 82% of caged fish and 59% of wild fish. Our results indicate that shallowly flooded rice fields are potential hotspots for MeHg bioaccumulation and, due to their global prevalence, suggest that agricultural wetlands may be important contributors to Me

  9. Relative entropy equals bulk relative entropy

    CERN Document Server

    Jafferis, Daniel L; Maldacena, Juan; Suh, S Josephine

    2015-01-01

    We consider the gravity dual of the modular Hamiltonian associated to a general subregion of a boundary theory. We use it to argue that the relative entropy of nearby states is given by the relative entropy in the bulk, to leading order in the bulk gravitational coupling. We also argue that the boundary modular flow is dual to the bulk modular flow in the entanglement wedge, with implications for entanglement wedge reconstruction.

  10. Coupling brane fields to bulk supergravity

    International Nuclear Information System (INIS)

    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  11. Coupling brane fields to bulk supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Parameswaran, Susha L. [Uppsala Univ. (Sweden). Theoretical Physics; Schmidt, Jonas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2010-12-15

    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  12. A lightweight field cage for a large TPC prototype for the ILC

    Energy Technology Data Exchange (ETDEWEB)

    Behnke, Ties; Dehmelt, Klaus; Diener, Ralf; Hallermann, Lea; Matsuda, Takeshi; Prahl, Volker; Schade, Peter

    2010-06-15

    We have developed and constructed the field cage of a prototype Time Projection Chamber for research and development studies for a detector at the International Linear Collider. This prototype has an inner diameter of 72 cm and a length of 61 cm. The design of the field cage wall was optimized for a low material budget of 1.21% of a radiation length and a drift field homogeneity of {delta}E/E

  13. A Lightweight Field Cage for a Large TPC Prototype for the ILC

    CERN Document Server

    Behnke, Ties; Diener, Ralf; Hallermann, Lea; Matsuda, Takeshi; Prahl, Volker; Schade, Peter

    2010-01-01

    We have developed and constructed the field cage of a prototype Time Projection Chamber for research and development studies for a detector at the International Linear Collider. This prototype has an inner diameter of 72 cm and a length of 61 cm. The design of the field cage wall was optimized for a low material budget of 1.21 % of a radiation length and a drift field homogeneity of Delta(E)/(E) less or equal 10^-4. Since November 2008 the prototype has been part of a comprehensive test beam setup at DESY and used as a test chamber for the development of Micro Pattern Gas Detector based readout devices.

  14. Growth of Pimelodus maculatus (Actinopterygii, Pimelodidae) in cages at different stocking densities

    OpenAIRE

    Saula Corrêa Afonso de Almeida; Alex Pires de Oliveira Nuñer

    2009-01-01

    This study aimed to evaluate the influence of densities 8, 32, 56 and 80 fish/m3 on the productive performance of Pimelodus maculatus in 1m3 cages installed in 0.19ha earthen ponds without water renewal, located on private property in Santo Amaro da Imperatriz, Santa Catarina. Fish were fed daily with extruded commercial ration containing 32% of crude protein, in a proportion of 5.0% of the stocked biomass. Fish were sampled monthly (30% of the stocked fish) in each cage to evaluate length, w...

  15. A lightweight field cage for a large TPC prototype for the ILC

    International Nuclear Information System (INIS)

    We have developed and constructed the field cage of a prototype Time Projection Chamber for research and development studies for a detector at the International Linear Collider. This prototype has an inner diameter of 72 cm and a length of 61 cm. The design of the field cage wall was optimized for a low material budget of 1.21% of a radiation length and a drift field homogeneity of ΔE/E -4. Since November 2008 the prototype has been part of a comprehensive test beam setup at DESY and used as a test chamber for the development of Micro Pattern Gas Detector based readout devices. (orig.)

  16. The Design and its Verification of the Double Rotor Double Cage Induction Motor

    Science.gov (United States)

    Sinha, Sumita; Deb, Nirmal K.; Biswas, Sujit K.

    2016-06-01

    The concept of a double rotor motor presented earlier and its equivalent circuit has been developed, showing a non-linear parameter content. The two rotors (which are recommended to be double cage type for development of high starting torque) can run with equal or unequal speed independently, depending on their individual loading. This paper presents the elaborate design procedure, step-by-step, for the double rotor double cage motor and verifies the designed data with that obtained from three separate tests (compared to two for conventional motor) on a prototype, such that optimum performance can be obtained from the motor.

  17. Status of BetaCage: an Ultra-sensitive Screener for Surface Contamination

    OpenAIRE

    Ahmed, Z.; Golwala, S. R.; Grant, D. R.; Kos, M.; Nelson, R. H.; Schnee, R. W.; Wang, B.

    2011-01-01

    BetaCage, a gaseous neon time-projection chamber, has been proposed as a viable screener for emitters of low-energy alphas and electrons to which commercial radioactivity counting techniques are insensitive. Using radiopure materials for construction, active and passive shielding from extrinsic backgrounds, large counting area and minimal detector mass, BetaCage will be able to achieve sensitivities of 10^(−5) counts keV^(−1) kg^(−1) day^(−1) in a few days of running time. We report on progre...

  18. Recombinant expression and purification of "virus-like" bacterial encapsulin protein cages.

    Science.gov (United States)

    Rurup, W Frederik; Cornelissen, Jeroen J L M; Koay, Melissa S T

    2015-01-01

    Ultracentrifugation, particularly the use of sucrose or cesium chloride density gradients, is a highly reliable and efficient technique for the purification of virus-like particles and protein cages. Since virus-like particles and protein cages have a unique size compared to cellular macromolecules and organelles, the rate of migration can be used as a tool for purification. Here we describe a detailed protocol for the purification of recently discovered virus-like assemblies called bacterial encapsulins from Thermotoga maritima and Brevibacterium linens. PMID:25358773

  19. Diffusive hydrogen inter-cage migration in hydrogen and hydrogen-tetrahydrofuran clathrate hydrates

    OpenAIRE

    H. Cao; English, Niall J.; MacElroy, J. M. Don

    2013-01-01

    Classical equilibrium molecular dynamics (MD) simulations have been performed to investigate the diffusive properties of inter-cage hydrogen migration in both pure hydrogen and mixed hydrogen-tetrahydrofuran sII hydrates at 0.05 kbar from 200 K and up to 250-260 K. For mixed H2- THF systems in which there is single H2 occupation of the small cage (labelled ‘1SC 1LC’), we found that no H2 migration occurs. However, for more densely-filled H2-THF and pure- H2 systems, in which th...

  20. Environmental impact of sea bass cage farming in the north Adriatic Sea

    OpenAIRE

    Domenico Lanari; Edo D’Agaro

    2010-01-01

    The main objective of the research was to reduce the organic and nutrient load under the net pen fish farms. An exper- iment was conducted to study the effects of artificial barriers fixed under a set of sea cages in order to reduce the envi- ronmental impact. The artificial barriers were made of four submerged galvanized steel pipes coated with plastic and placed on the sea floor (10 m depth) in the Trieste gulf. The experimental design was as follows: control (C), cages with barriers (B), c...

  1. Palladium-Catalyzed Regioselective Diarylation of o-Carboranes By Direct Cage B-H Activation.

    Science.gov (United States)

    Quan, Yangjian; Xie, Zuowei

    2016-01-22

    Palladium-catalyzed intermolecular coupling of o-carborane with aromatics by direct cage B-H bond activation has been achieved, leading to the synthesis of a series of cage B(4,5)-diarylated-o-carboranes in high yields with excellent regioselectivity. Traceless directing group -COOH plays a crucial role for site- and di-selectivity of such intermolecular coupling reaction. A Pd(II)-Pd(IV)-Pd(II) catalytic cycle is proposed to be responsible for the stepwise arylation. PMID:26463595

  2. Bulk scalar field in DGP braneworld cosmology

    CERN Document Server

    Ansari, Rizwan ul Haq

    2007-01-01

    We investigated the effects of bulk scalar field in the braneworld cosmological scenario. The Friedmann equations and acceleration condition in presence of the bulk scalar field for a zero tension brane and cosmological constant are studied. In DGP model the effective Einstein equation on the brane is obtained with bulk scalar field. The rescaled bulk scalar field on the brane in the DGP model behaves as an effective four dimensional field, thus standard type cosmology is recovered. In present study of the DGP model, the late-time accelerating phase of the universe can be explained .

  3. Metal ion cage complexes as imaging agents for cancer cells

    International Nuclear Information System (INIS)

    Full text: Cage ligands are very attractive for use in radiolabelling antibodies. Their synthesis is based around Co(III) octahedral co-ordination chemistry and they may be easily derivatised for attachment to antibodies. They are known to form kinetically inert metal complexes. Copper-64 (t1/2 = 12.7 h) has been identified as having potential value in diagnostic and therapeutic application. Its positron annihilation radiation is useful for PET imaging, while its beta (Emax 578 keV, 37.2 %) emissions may also be suitable for therapy. In the current study, the new hexa-aza-cryptand, 1 -N-(4-amino-benzyl)-3,6,10,13,16,19-hexaaza-bicyclo[6.6.6]eicosane- 1,8-diamine, or SarAr, has been synthesised specifically for radiolabelling antibodies with 64Cu and a kit formulation has been produced. The resulting radiolabelled immunoconjugate (64Cu-SarArB-72.3) was injected into nude mice bearing LS174t colorectal carcinoma. Clearance of 64CuSarAr-B72.3 from the liver and kidneys was typical of a whole IgG antibody. Tumour localisation was comparable to similar radiolabelled immunoconjugates (38± 5 % ID/g at 48 hours). Biodistribution studies of 123I- and 111In- radiolabelled B72.3 were conducted in the same animal model. MIRDOSE 3 was used to compare target to non-target dose of their analogous therapeutic counterparts (90Y and 131I respectively) with 64Cu-SarAr-B72.3. Total body dose for 64Cu-SarAr-B72.3 was significantly lower (0.09 rad/mCi) than analogous products (131I-B72.3, 2.64 rad/mCi; 90Y- B72.3, 2.387 rad/mCi) while still providing enough dose to small tumours to be potentially therapeutic. In order to assess therapeutic effect of 64Cu, a biological study was conducted over a 12 month period. Nude mice bearing tumours between 3.5 - 5.5 mm in length were injected with various doses (0, 10, 20, 30, 40 MBq) of 64Cu-SarAr-B72.3. Animals were regularly monitored for tumour size, animal mass, behavioural and physical abnormalities (e.g. movement / gait, food intake and

  4. Beak condition and cage density determine abundance and spatial distribution of northern fowl mites, Ornithonyssus sylviarum, and chicken body lice, Menacanthus stramineus, on caged laying hens.

    Science.gov (United States)

    Mullens, B A; Chen, B L; Owen, J P

    2010-12-01

    Adult White Leghorn hens (Hy-Line strain W-36) were inoculated with either northern fowl mites or chicken body lice, and the ectoparasite populations were monitored over periods of 9 to 16 wk. Two beak conditions (beak trimmed or beak intact) and 2 housing densities (1 or 2 hens per 25 × 31 cm suspended wire cage) were tested. Populations of both ectoparasites were at least 10 times lower on beak-intact hens compared with populations on beak-trimmed hens. Cage density did not influence mite numbers, but higher numbers of lice (2 to 3 times) developed on hens held at the higher cage density. Louse distribution on the body and louse population age structure were also influenced by host beak condition. Beak-intact hens had a higher proportion of lice under the wings, whereas beak-trimmed hens had the majority of lice on the lower abdomen. Louse populations on beak-trimmed hens also comprised relatively more immature stages than populations found on beak-intact hens. The effects are likely related to decreased grooming efficiency by beak-trimmed hens and, in the case of lice, the higher host density. The high mite and louse populations on most commercial caged laying hens are probably a direct result of beak trimming. However, selection of more docile breeds that can be held without trimming may allow the hens themselves to reduce ectoparasites below economically damaging levels. This could benefit producers, animal welfare advocates, and human health by reducing 1) costs of beak trimming, 2) pesticide treatment costs (including human and bird chemical exposure concerns), and 3) objections to beak trimming from the animal welfare community. PMID:21076093

  5. Spray washing, absorbent cornstarch powder, and dry time to reduce bacterial numbers on soiled transport cage flooring

    Science.gov (United States)

    Broiler transport cages are often used repeatedly without washing and fecal matter deposited on the floor surface can transfer Campylobacter from one flock to another. Allowing feces to dry is an effective but slow and logistically impractical means to kill Campylobacter in soiled transport cages. ...

  6. Do cage effects influence tumor incidence? An examination of laboratory animal carcinogenicity studies utilizing Fischer 344 rats.

    Science.gov (United States)

    Haseman, J K

    1988-08-01

    Approximately 125 carcinogenicity studies in Fischer 344 rats conducted by the National Toxicology Program (NTP) were examined to determine the frequency with which cage effects were associated with observed carcinogenic responses. All studies involving groups of 50 rats housed five per cage and showing evidence of chemically-related carcinogenicity were considered. For each of these experiments, two statistical analyses were carried out for each dosed and control group: (i) a test to determine whether or not the occurrence of tumors clustered within cages; and (ii) an evaluation to determine whether or not tumor incidences differed significantly between differing cage shelf levels. These analyses showed that the numbers of statistically significant (P less than 0.05 or P less than 0.01) effects were consistent with the number expected by chance alone. Thus, cage-related factors appeared to have little or no impact upon tumor incidence in these particular studies. Experimental design protocols now used by the NTP (which include random assignment of animals to cages; random assignment of columns of cages to dosed and control groups; and periodic rotation of cage location) further reduce the likelihood that factors associated with the housing of the animals could influence tumor incidence in current studies. PMID:3183292

  7. Spray washing, absorbent corn starch powder and dry time to reduce bacterial numbers on soiled boiler transport cage flooring

    Science.gov (United States)

    Most broilers in the U.S. are transported live to slaughter facilities in cages with fiberglass floors. Cages are often used repeatedly without washing and fecal matter deposited on the floor surface can transfer Campylobacter from one flock to another. Drying feces out between uses is an effectiv...

  8. Palladium-catalyzed regioselective intramolecular coupling of o-carborane with aromatics via direct cage B-H activation.

    Science.gov (United States)

    Quan, Yangjian; Xie, Zuowei

    2015-03-18

    Palladium-catalyzed intramolecular coupling of o-carborane with aromatics via direct cage B-H bond activation has been achieved, leading to the synthesis of a series of o-carborane-functionalized aromatics in high yields with excellent regioselectivity. In addition, the site selectivity can also be tuned by the substituents on cage carbon atom. PMID:25747772

  9. Effect of Cage-Wash Temperature on the Removal of Infectious Agents from Caging and the Detection of Infectious Agents on the Filters of Animal Bedding-Disposal Cabinets by PCR Analysis.

    Science.gov (United States)

    Compton, Susan R; Macy, James D

    2015-11-01

    Efficient, effective cage decontamination and the detection of infection are important to sustainable biosecurity within animal facilities. This study compared the efficacy of cage washing at 110 and 180 °F on preventing pathogen transmission. Soiled cages from mice infected with mouse parvovirus (MPV) and mouse hepatitis virus (MHV) were washed at 110 or 180 °F or were not washed. Sentinels from washed cages did not seroconvert to either virus, whereas sentinels in unwashed cages seroconverted to both agents. Soiled cages from mice harboring MPV, Helicobacter spp., Mycoplasma pulmonis, Syphacia obvelata, and Myocoptes musculinus were washed at 110 or 180 °F or were not washed. Sentinels from washed cages remained pathogen-free, whereas most sentinels in unwashed cages became infected with MPV and S. obvelata. Therefore washing at 110 or 180 °F is sufficient to decontaminate caging and prevent pathogen transmission. We then assessed whether PCR analysis of debris from the bedding disposal cabinet detected pathogens at the facility level. Samples were collected from the prefilter before and after the disposal of bedding from cages housing mice infected with both MPV and MHV. All samples collected before bedding disposal were negative for parvovirus and MHV, and all samples collected afterward were positive for these agents. Furthermore, all samples obtained from the prefilter before the disposal of bedding from multiply infected mice were pathogen-negative, and all those collected afterward were positive for parvovirus, M. pulmonis, S. obvelata, and Myocoptes musculinus. Therefore the debris on the prefilter of bedding-disposal cabinets is useful for pathogen screening. PMID:26632784

  10. Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein

    DEFF Research Database (Denmark)

    Tang, Sheila Tuyet; Chang, HC; Roeben, A; Wischnewski, D; Wischnewski, N; Kerner, MJ; Hartl, FU; Hayer-Hartl, M

    2006-01-01

    . Additionally, interactions with the C-terminal, mildly hydrophobic Gly-Gly-Met repeat sequences of GroEL protruding into the cavity, and repulsion effects from the negatively charged cavity wall were required for rapid folding of some proteins. We suggest that by combining these features, the chaperonin cage......GroEL and GroES form a chaperonin nano-cage for proteins up to similar to 60 kDa to fold in isolation. Here we explored the structural features of the chaperonin cage critical for rapid folding of encapsulated substrates. Modulating the volume of the GroEL central cavity affected folding speed in...... accordance with confinement theory. Small proteins (similar to 30 kDa) folded more rapidly as the size of the cage was gradually reduced to a point where restriction in space slowed folding dramatically. For larger proteins (similar to 40-50 kDa), either expanding or reducing cage volume decelerated folding...

  11. 27 CFR 20.191 - Bulk articles.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk articles. 20.191... Users of Specially Denatured Spirits Operations by Users § 20.191 Bulk articles. Users who convey articles in containers exceeding one gallon may provide the recipient with a photocopy of subpart G of...

  12. Vergleich klinischer und radiologischer Parameter nach anteriorer Diskektomie und Fusion der Halswirbelsäule mit Polyetheretherketon- und Titan-Cages

    OpenAIRE

    Özdemir, Soner

    2015-01-01

    Background: Compared with polyetheretherketone (PEEK) titanium (TTN) cages have a higher modulus of elasticity and are reported to show a higher loss of correction and more frequent cage subsidence after anterior cervical discectomy and fusion (ACDF). Direct comparison of both cage types appears to favour PEEK cages to maintain cervical interspace height and achieve better fusion in patients with a degenerative disc disease (DDD), but clinical studies on this subject are very rare. Metho...

  13. Disparities in Ammonia, Temperature, Humidity, and Airborne Particulate Matter between the Micro-and Macroenvironments of Mice in Individually Ventilated Caging

    OpenAIRE

    Rosenbaum, Matthew D.; VandeWoude, Susan; Volckens, John; Johnson, Thomas E

    2010-01-01

    Animal room environmental parameters typically are monitored with the assumption that the environment within the cage closely mirrors the room environment. This study evaluated that premise by examining macro- (room) and microenvironmental (cage) parameters in individually ventilated cages housing mice with variable amounts of bedding over a period of 17 d without cage changes. Intracage ammonia levels remained within recommended human guidelines but were higher than room levels, confirming t...

  14. Bulk equations of motion from CFT correlators

    CERN Document Server

    Kabat, Daniel

    2015-01-01

    To O(1/N) we derive, purely from CFT data, the bulk equations of motion for interacting scalar fields and for scalars coupled to gauge fields and gravity. We first uplift CFT operators to mimic local AdS fields by imposing bulk microcausality. This requires adding an infinite tower of smeared higher-dimension double-trace operators to the CFT definition of a bulk field, with coefficients that we explicitly compute. By summing the contribution of the higher-dimension operators we derive the equations of motion satisfied by these uplifted CFT operators and show that we precisely recover the expected bulk equations of motion. We exhibit the freedom in the CFT construction which corresponds to bulk field redefinitions.

  15. Gene expression in caged fish as indicators of contaminants exposure in tropical karstic water bodies.

    Science.gov (United States)

    Rodríguez-Fuentes, Gabriela; Luna-Ramírez, Karen S; Soto, Mélina; Richardson, Kristine L

    2012-04-01

    Karstic areas in Yucatan are very permeable, which allows contaminants to move rapidly into the aquifer. In the present study, we evaluated gene expression of vitellogenin (VTG) and cytochrome P-450 1A (CYP1A) in caged juvenile zebrafish deployed for 15 days in 13 different water bodies, cenotes and aguadas, throughout karstic region of the Yucatan peninsula. Gene expression was evaluated using qRT-PCR. Results indicated induction of VTG in 7 water bodies with respect to reference cage. The highest relative VTG expression, about 3000 times higher than reference cage, was found in an aguada close to a cattle farm. CYP1A induction with respect to reference cage was observed in 3 water bodies, all of them located near villages or used for tourist activities. Pollutants and biomarkers of effect should be monitored in these water bodies in order to have a better understanding of the actual levels of pollutants that are present at Yucatan's aquifer and the potential risk to human and environmental health. PMID:22014761

  16. A new cytotoxic caged polyprenylated xanthone from the resin of Garcinia hanburyi

    Institute of Scientific and Technical Information of China (English)

    Li Li Wang; Zhan Lin Li; Yong Peng Xu; Xiao Qiu Liu; Yue Hu Pei; Yong Kui Jing; Hui Ming Hua

    2008-01-01

    A new caged polyprenylated xanthone,gambogic aldehyde(1),was isolated from the resin of Garcinia hanburyi.Its structure was elucidated on the basis of spectral data including 1D and 2D NMR data.In addition.the antiproliferative ability of compound 1 was determined in mouse leukemia P388 and P388/ADR ceils.

  17. Trace elements in two marine fish cultured in fish cages in Fujian province, China

    Energy Technology Data Exchange (ETDEWEB)

    Onsanit, Sarayut; Ke Caihuan; Wang Xinhong; Wang Kejian [State Key Laboratory for Marine Environmental Science, College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005 (China); Wang Wenxiong, E-mail: wwang@ust.h [State Key Laboratory for Marine Environmental Science, College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005 (China)

    2010-05-15

    Two cultured marine fish, the Japanese seabass (Lateolabrax japonicus) and red seabream (Pagrus major) were collected from eight fish cage sites along the coast of Fujian province in China. The concentrations of Ag, As, Cd, Co, Cu, Fe, Mn, Se, and Zn in their muscle, stomach and liver tissue were quantified. The risk of these trace elements to humans through fish consumption was then assessed. The highest concentrations of As, Cd, Se and Zn in fish feed from fish cages were found in Dongshan Station. Moreover, the As levels in the muscles of both species at all sites were generally higher than China's national standard (>1.0 mug/g). Trace element concentrations in two marine fish followed the order of livers > stomachs > muscles. Although the As levels in two marine caged fish exceeded the permissible standards, the estimated daily intake of As did not exceed the reference dose guideline established by US EPA. For other trace elements examined in this study, their concentrations did not exceed the permissible concentrations of the international standards. - As levels in two marine caged fish from China exceeded the permissible standards, whereas the levels of others trace elements did not exceed the permissible concentrations.

  18. Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging.

    Science.gov (United States)

    Anzalone, Andrew V; Chen, Zhixing; Cornish, Virginia W

    2016-07-19

    We report the design and synthesis of a photoactivatable azido-acyl oxazine fluorophore. Photoactivation is achieved cleanly and rapidly with UV light, producing a single fluorescent oxazine photoproduct. We demonstrate the utility of azido-acyl caged oxazines for protein specific labeling in living mammalian cells using the TMP-tag technology. PMID:27377037

  19. Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.

    Science.gov (United States)

    Faggi, Enrico; Vicent, Cristian; Luis, Santiago V; Alfonso, Ignacio

    2015-12-28

    Pseudopeptidic molecular cages are appealing receptors since they can display different polar and non-polar interaction sites in a modular framework and a controlled disposition. Inspired by previous host-guest knowledge, two pseudopeptidic molecular cages based on serine and threonine (CySer and CyThr, respectively) were designed and synthesized as hosts for the binding of the four possible stereoisomers of the Ac-Glu-Tyr-OH dipeptide, a target sequence of tyrosine kinases. The careful NMR titration experiments in aqueous acetonitrile allowed the determination of the binding constants and reflected a difference in the stability of the corresponding diastereomeric host-guest complexes. The CySer cage proved to be slightly more efficient than the CyThr counterpart, although both showed similar stereoselectivity trends: LL > DD ≥ LD > DL. This stereoselective binding was retained in the gas phase, as shown by ESI-MS competition experiments using the enantiomer-labelled method (EL), as well as CID experiments. Thus, the MS-determined discriminations follow the same trends observed by NMR, suggesting that the stereoselectivity observed for these systems must be mainly dictated by the polar host-guest interactions. Despite the stereoselective binding of short peptide sequences in competitive media being a challenging issue in supramolecular chemistry, our results demonstrate the power of pseudopeptidic cages in molecular recognition with foreseen implications in chemical biology. PMID:26481115

  20. Photo-control of nitric oxide synthase activity using a caged isoform specific inhibitor.

    Science.gov (United States)

    Montgomery, Heather J; Perdicakis, Basil; Fishlock, Dan; Lajoie, Gilles A; Jervis, Eric; Guy Guillemette, J

    2002-06-01

    Nitric oxide (NO) plays a critical role in a number of physiological processes and is produced in mammalian cells by nitric oxide synthase (NOS) isozymes. Because of the diverse functions of NO, pharmaceutical interventions which seek to abrogate adverse effects of excess NOS activity must not interfere with the normal regulation of NO levels in the body. A method has been developed for the control of NOS enzyme activity using the localized photochemical release of a caged isoform-specific NOS inhibitor. The caged form of an iNOS inhibitor has been synthesized and tested for photosensitivity and potency. UV and multiphoton uncaging were verified using a hemoglobin-based assay. IC(50) values were determined for the inhibitor (70+/-11 nM), the caged inhibitor (1098+/-172 nM), the UV uncaged inhibitor (67+/-26 nM) and the multiphoton uncaged inhibitor (73+/-11 nM). UV irradiation of the caged inhibitor resulted in a 86% reduction in iNOS activity after 5 min. Multiphoton uncaging had an apparent first order time constant of 0.007+/-0.001 min(-1). A therapeutic range exists, with molar excess of inhibitor to enzyme from 3- to 7-fold, over which the full dynamic range of the inhibition can be exploited. PMID:11937350

  1. Protein Nanocontainers from Nonviral Origin: Testing the Mechanics of Artificial and Natural Protein Cages by AFM.

    Science.gov (United States)

    Heinze, K; Sasaki, E; King, N P; Baker, D; Hilvert, D; Wuite, G J L; Roos, W H

    2016-07-01

    Self-assembling protein nanocontainers are promising candidates for an increasingly wide scope of purposes. Their applications range from drug delivery vehicles and imaging agents to nanocompartments for controlled enzymatic activity. In order to exploit their full potential in these different fields, characterization of their properties is vital. For example, their mechanical properties give insight into the stability of a particle as a function of their internal content. The mechanics can be probed by atomic force microscopy nanoindentation, and while this single particle method is increasingly used to probe material properties of viral nanocages, it has hardly been used to characterize nonviral nanocages. Here we report nanoindentation studies on two types of nonviral nanocontainers: (i) lumazine synthase from Aquifex aeolicus (AaLS), which naturally self-assembles into icosahedral cages, and (ii) the artificial protein cage O3-33 originating from a computational design approach. In addition, we tested particles that had been engineered toward improved cargo loading capacity and compared these nanocages in empty and loaded states. We found that the thermostable AaLS cages are stiffer and resist higher forces before breaking than the O3-33 particles, but that mutations affecting the size of AaLS particles have a dramatic effect on their structural stability. Furthermore, we show that cargo packaging can occur while maintaining the cage's mechanical properties. PMID:27187612

  2. Photoactivatable Drug-Caged Fluorophore Conjugate Allows Direct Quantification of Intracellular Drug Transport

    OpenAIRE

    Agasti, Sarit S.; Laughney, Ashley M.; Kohler, Rainer H.; Weissleder, Ralph

    2013-01-01

    We report here a method that utilizes photoactivatable drug-caged fluorophore conjugate to quantify intracellular drug trafficking processes at single cell resolution. Photoactivation is performed in labeled cellular compartments to visualize intracellular drug exchange at physiologic conditions, without the need for washing, facilitating its translation to in vivo cancer models.

  3. That Entertainment Called a Discussion: The Critical Arts Pedagogy of John Cage

    Science.gov (United States)

    Muller, Otto

    2015-01-01

    Just as John Cage used chance techniques to relinquish control in his practice as a composer, he used pedagogical techniques that facilitated shared learning and experimentation. The tenets of Critical Pedagogy, as laid out by Paulo Freire in "The Pedagogy of the Oppressed," offer insights into the structures and strategies implicit in…

  4. Friction moment analysis of space gyroscope bearing with ribbon cage under ultra-low oscillatory motion

    Directory of Open Access Journals (Sweden)

    Jiang Shaona

    2014-10-01

    Full Text Available This paper presents the model of calculating the total friction moment of space gyroscope ball bearings which usually work under ultra-low oscillatory motion and are very sensitive to the friction moment. The aim is to know the proportion of the friction moment caused by each frictional source in the bearing’s total friction moment, which is helpful to optimize the bearing design to deduce the friction moment. In the model, the cage dynamic equations considering six degree-of-freedom and the balls dynamic equations considering two degree-of-freedom were solved. The good trends with different loads between the measured friction moments and computational results prove that the model under constant rate was validated. The computational results show that when the speed was set at 5 r/min, the bearing’s maximum total friction moment when oscillation occurred was obviously larger than that occurred at a constant rate. At the onset of each oscillatory motion, the proportion of the friction moment caused by cage in the bearing’s total friction moment was very high, and it increased with the increasing speed. The analyses of different cage thicknesses and different clearances between cage pocket and ball show that smaller thickness and clearance were preferred.

  5. PRODUCTIVITY OF LAYERS AND EGG QUALITY IN FREE RANGE AND CAGE SYSTEM OF HOUSING

    Directory of Open Access Journals (Sweden)

    Đ. Senčić

    2006-12-01

    Full Text Available The research was conducted with two groups of Lohmann Brown hybrid layers. Production of eggs lasted for 52 weeks. A control group of layers was kept in the conventional housing system, that is, in cages, while experimental group was kept in the free range system. Layers from the free range system, compared to those kept in cages, laid fewer eggs, (266:295, they consumed more feed on daily basis (129 g : 115 g, more feed per kilogram of egg weight (2.83 kg : 2.35 kg, they had higher mortality rate (6.80 % : 5.50 % and lower end of lay body weight (1.95 kg : 2.10 kg. Eggs from free range layers, compared to those from the cages system, had significantly (P0.05 were determined between the free range and the cages system of housing hens. Considering somewhat lower productivity and higher mortality rate of hens, higher feed consumption per kilogram of egg mass, but also better quality of eggs, profitability of egg production in the free range system will depend, to the maximum extent, on market evaluation of the production.

  6. Examination of Free Choice of Rabbits among Different Cage-floors

    Directory of Open Access Journals (Sweden)

    Zsolt Matics

    2003-12-01

    Full Text Available Rabbits were placed in a block of cages with a floor-area of 2 m2. The animals could move freely among the cages, through swing doors. All the four cages were totally equal, they only differed in the floor (planked by OSB panel, plastic-slat, plastic-mesh or wire-mesh. 24 or 32 rabbits, weaned at 21 days of age were placed into the block. During the experiment (until 10 weeks of age the free choice of rabbits among the cage-floors was studied weekly with the help of 24-hour video recordings. The soiled and wet (by urine planked-floor was chosen by fewer and fewer rearing rabbits after the first week. Placing both 24 or 32 rabbits into the block, the plastic mesh floor was preferred. With the increase of age the choice of plastic-mesh, wire-mesh and plastic-slat floor became similar. The increase of both number and weight of rabbits in 1 m2 influenced the acceptance of different floors. Rearing 32 rabbits together, the choice of the 3 preferred floor types became similar at 7.5 weeks of age, while rearing 24 rabbits in a group, it became similar only at 9.5 weeks of age.

  7. Examination of Free Choice of Rabbits among Different Cage-floors

    Directory of Open Access Journals (Sweden)

    Zsolt Matics

    2003-12-01

    Full Text Available Rabbits were placed in a block of cages with a floor-area of 2 m2. The animals could move freely among the cages, through swing doors. All the four cages were totally equal, they only differed in the floor (planked by OSB panel, plastic-slat, plastic-mesh or wire-mesh. 24 or 32 rabbits, weaned at 21 days of age were placed into the block. During the experiment (until 10 weeks of age the free choice of rabbits among the cage-floors was studied weekly with the help of 24-hour video recordings. The soiled and wet (by urine planked-floor was chosen by fewer and fewer rearing rabbits after the first week. Placing both 24 or 32 rabbits into the block, the plastic mesh floor was preferred. With the increase of age the choice ofplastic-mesh, wire-mesh and plastic-slat floor became similar. The increase of both number and weight of rabbits in 1 m2 influenced the acceptance of different floors. Rearing 32 rabbits together, the choice of the 3 preferred floor types became similar at 7.5 weeks of age, while rearing 24 rabbits in a group, it became similar only at 9.5 weeks of age.

  8. Laying Performance of Wareng Chicken under Free Choice Feeding and Different Cage Density

    Directory of Open Access Journals (Sweden)

    S. Iskandar

    2011-04-01

    Full Text Available The aim of the experiment was to explore the possibility of using free choice feeding technique under different cage density for unselected native chicken. Eighty hens of laying Wareng chicken were divided into two feeding systems. Half of them were fed complete commercial diet of 17% crude protein, with 2800 kcal ME/kg and the other half were subjected to free choice diet. The diets were in mash form and placed in sufficient feed troughs in front of each cage. Each cage was occupied by four or six hens. Free choice feeding hens were served with commercial concentrate (30% crude protein, ground corn and oyster shell, placed separately in feed troughs. Observation was carried out during 24 weeks laying period, starting from 20 to 44 weeks of age. The results showed that egg production (9.35% hen day, and the intake of feed (42.74 g/day, protein (7.01 g/day, energy (116.6 kcal ME/day, calcium (1.99 g/day and phosphorus (0.22 g/day were not affected (P>0.05 by feeding system nor by cage density. The results however indicated that free choice feeding technique provided sufficient nutrients in supporting maximum egg production of unselected native chicken.

  9. Effect of rib cage and abdominal restriction on total respiratory resistance and reactance.

    Science.gov (United States)

    van Noord, J A; Demedts, M; Clément, J; Cauberghs, M; Van de Woestijne, K P

    1986-11-01

    In 14 healthy male subjects we studied the effects of rib cage and abdominal strapping on lung volumes, airway resistance (Raw), and total respiratory resistance (Rrs) and reactance (Xrs). Rib cage, as well as abdominal, strapping caused a significant decrease in vital capacity (respectively, -36 and -34%), total lung capacity (TLC) (-31 and -27%), functional residual capacity (FRC) (-28 and -28%), and expiratory reserve volume (-40 and -48%) and an increase in specific airway conductance (+24 and +30%) and in maximal expiratory flow at 50% of control TLC (+47 and +42%). The decrease of residual volume (RV) was significant (-12%) with rib cage strapping only. Abdominal strapping resulted in a minor overall increase in Rrs, whereas rib cage strapping produced a more marked increase at low frequencies; thus a frequency dependence of Rrs was induced. A similar pattern, but with lower absolute values, of Rrs was obtained by thoracic strapping when the subject was breathing at control FRC. Xrs was decreased, especially at low frequencies, with abdominal strapping and even more with thoracic strapping; thus the resonant frequency of the respiratory system was shifted toward higher frequencies. Partitioning Rrs and Xrs into resistance and reactance of lungs and chest wall demonstrated that the different effects of chest wall and abdominal strapping on Rrs and Xrs reflect changes mainly of chest wall mechanics. PMID:3781983

  10. Use, fate and ecological risks of antibiotics applied in tilapia cage farming in Thailand

    NARCIS (Netherlands)

    Rico, A.; Oliveira, R.; McDonough, S.; Matser, A.; Khatikarn, J.; Satapornvanit, K.; Nogueira, A.J.A.; Soares, A.M.V.M.; Domingues, I.; Brink, van den P.J.

    2014-01-01

    The use, environmental fate and ecological risks of antibiotics applied in tilapia cage farming were investigated in the Tha Chin and Mun rivers in Thailand. Information on antibiotic use was collected through interviewing 29 farmers, and the concentrations of the most commonly used antibiotics, oxy

  11. Different denaturation pathways of TrpCage minipeptide triggered by urea and guanidinium

    Czech Academy of Sciences Publication Activity Database

    Heyda, J.; Jungwirth, Pavel; Dzubiella, J.

    Praha : Ústav organické chemie a biochemie AV ČR, v. v. i, 2012. s. 34-34. ISBN 978-80-86241-47-0. [Prague Protein Spring Meeting 2012. 03.05.2012-06.05.2012, Praha] Institutional support: RVO:61388963 Keywords : TrpCage * denaturation * urea * guanidinium Subject RIV: CF - Physical ; Theoretical Chemistry

  12. Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein

    Czech Academy of Sciences Publication Activity Database

    Heyda, Jan; Kožíšek, Milan; Bednárová, Lucie; Thompson, G.; Konvalinka, Jan; Vondrášek, Jiří; Jungwirth, Pavel

    2011-01-01

    Roč. 115, č. 28 (2011), s. 8910-8924. ISSN 1520-6106 R&D Projects: GA MŠk LC512; GA ČR GA203/08/0114 Institutional research plan: CEZ:AV0Z40550506 Keywords : trp-cage denaturation * urea * guanidinium * molecular dynamics Subject RIV: CC - Organic Chemistry Impact factor: 3.696, year: 2011

  13. Maternal Obesity, Cage Density, and Age Contribute to Prostate Hyperplasia in Mice.

    Science.gov (United States)

    Benesh, Emily C; Gill, Jeff; Lamb, Laura E; Moley, Kelle H

    2016-02-01

    Identification of modifiable risk factors is gravely needed to prevent adverse prostate health outcomes. We previously developed a murine precancer model in which exposure to maternal obesity stimulated prostate hyperplasia in offspring. Here, we used generalized linear modeling to evaluate the influence of additional environmental covariates on prostate hyperplasia. As expected from our previous work, the model revealed that aging and maternal diet-induced obesity (DIO) each correlated with prostate hyperplasia. However, prostate hyperplasia was not correlated with the length of maternal DIO. Cage density positively associated with both prostate hyperplasia and offspring body weight. Expression of the glucocorticoid receptor in prostates also positively correlated with cage density and negatively correlated with age of the animal. Together, these findings suggest that prostate tissue was adversely patterned during early life by maternal overnutrition and was susceptible to alteration by environmental factors such as cage density. Additionally, prostate hyperplasia may be acutely influenced by exposure to DIO, rather than occurring as a response to worsening obesity and comorbidities experienced by the mother. Finally, cage density correlated with both corticosteroid receptor abundance and prostate hyperplasia, suggesting that overcrowding influenced offspring prostate hyperplasia. These results emphasize the need for multivariate regression models to evaluate the influence of coordinated variables in complicated animal systems. PMID:26243546

  14. Solid-state NMR spectroscopy of molecular hydrogen trapped inside an open-cage fullerene

    OpenAIRE

    Carravetta, M.; Murata, Y; Murata, M.; Heinmaa, I.; Stern, R.; Tontcheva, A.; Samoson, A.; Y. Rubin; Komatsu, K.; Levitt, M.H.

    2004-01-01

    Solid-state 1H experiments were performed an open-cage fullerene hosting molecular hydrogen. The anisotropy of the molecular hydrogen rotation was studied by double-quantum magic-angle-spinning NMR. The time scale of the molecular hydrogen rotation was estimated by spin-lattice relaxation measurements as a function of temperature.

  15. Parameters identification of the compound cage rotor induction machine based on linearized Kalman filtering

    Institute of Scientific and Technical Information of China (English)

    王铁成; 李伟力; 孙建伟

    2003-01-01

    A mathematical model has been built up for compound cage rotor induction machine with the rotor re-sistance and leakage inductance in the model identified through Kalman filtering method. Using the identifiedparameters, simulation studies are performed, and simulation results are compared with testing results.

  16. Disorder of Hydrofluorocarbon Molecules Entrapped in the Water Cages of Structure I Clathrate Hydrate.

    Science.gov (United States)

    Takeya, Satoshi; Udachin, Konstantin A; Moudrakovski, Igor L; Ohmura, Ryo; Ripmeester, John A

    2016-05-23

    Water versus fluorine: Clathrate hydrates encaging hydrofluorocarbons as guests show both isotropic and anisotropic distributions within host water cages, depending on the number of fluorine atoms in the guest molecule; this is caused by changes in intermolecular interactions to host water molecules in the hydrates. PMID:27105807

  17. 25 CFR 542.14 - What are the minimum internal control standards for the cage?

    Science.gov (United States)

    2010-04-01

    ... balance of all customer cash deposits that are in the cage/vault inventory or accountability; and (iii... shall comply with procedures for the receipt, inventory, storage, and destruction of gaming chips and... reconciled to the general ledger each month. The reconciliation and any follow-up performed shall...

  18. INTERACTIVE EFFECT OF CAGE DENSITY AND DIETARY BLACK CUMIN LEVEL ON PRODUCTIVE EFFICIENCY IN BROILER CHICKENS

    Directory of Open Access Journals (Sweden)

    L. D. Mahfudz

    2015-09-01

    Full Text Available The present research was aimed to evaluate an interactive effect of cage density and level ofdietary black cumin (BC on productive efficiency of broiler chickens. A total of 270 broiler chickens(initial body weight of 163.12 ± 8.10g were allocated into a completely randomized design with a 3 x 3factorial pattern. The first factor was the cage density (bird/m2 namely, D1 = 8; D2 = 10, and D3 = 12.The second factor was BC level (%, namely, B1 = 1; B2 = 2, and B3 = 3. Feed consumption, bodyweight gain (BWG, feed conversion ratio (FCR, protein digestibility, and income over feed cost(IOFC were the parameters measured. Data were subjected to ANOVA and continued to Duncan test.No interaction between cage density and black cumin on all parameters was observed. Feedconsumption and FCR were increased, but BWG was lowered significantly (P<0.05 due to the cagedensities of 10 and 12 birds/m2 on weeks 2 and 3. Protein digestibility was significantly increased byfeeding 2 and 3% BC. IOFC decreased significantly (P<0.05 when cage densities were 10 and 12birds/m2. In conclusion, the improvement of productive efficiency of broiler chicken reared at the cagedensity of 12 birds /m2 can be sufficiently achieved by feeding 1% black cumin.

  19. Novel approach to the behavioural characterization of inbred mice : automated home cage observations

    NARCIS (Netherlands)

    de Visser, L; van den Bos, R; Kuurman, W W; Kas, M J H; Spruijt, B M

    2006-01-01

    Here we present a newly developed tool for continuous recordings and analysis of novelty-induced and baseline behaviour of mice in a home cage-like environment. Aim of this study was to demonstrate the strength of this method by characterizing four inbred strains of mice, C57BL/6, DBA/2, C3H and 129

  20. Nicolas Cage otsib kadunud tütart naistesaarelt / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2006-01-01

    Õudusfilm "Ohvripidu" : režissöör Neil LaBute : peaosas Nicholas Cage : Ameerika Ühendriigid - Saksamaa 2006. Film on uusversioon briti 1973.a. filmist, mille režissöör oli Robin Hardy ja ühes peaosadest Christopher Lee

  1. Alternatives for the battery cage system: a comparison of economic, environmental and societal performance

    NARCIS (Netherlands)

    Zijpp, van der A.J.; Mollenhorst, H.; Berentsen, P.B.M.; Boer, de I.J.M.

    2006-01-01

    The ban on the battery cage system in the European Union after 2012, mainly due to impaired hen welfare, forces farmers to change to alternative housing systems for laying hens. Large-scale introduction of more hen-friendly systems, however, requires a comparison of these systems on their economic,

  2. Energy loss caused by shielding effect of steel cage outside source tube

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The energy loss, produced by shielding effect of steel cage outside the source tube, is quite considerable.With PENELOPE software package, MC results have been obtained based on the simulation of different source conformations. The result illustrates that the naked source tubes can improve the utilization ratio of the cobalt facilities. It demonstrates the applied value of the naked source tube in engineering.

  3. FUZZY LOGIC BASED INTELLIGENT CONTROL OF A VARIABLE SPEED CAGE MACHINE WIND GENERATION SYSTEM

    Science.gov (United States)

    The paper describes a variable-speed wind generation system where fuzzy logic principles are used to optimize efficiency and enhance performance control. A squirrel cage induction generator feeds the power to a double-sided pulse width modulated converter system which either pump...

  4. Friction moment analysis of space gyroscope bearing with ribbon cage under ultra-low oscillatory motion

    Institute of Scientific and Technical Information of China (English)

    Jiang Shaona; Chen Xiaoyang; Gu Jiaming; Shen Xuejin

    2014-01-01

    This paper presents the model of calculating the total friction moment of space gyro-scope ball bearings which usually work under ultra-low oscillatory motion and are very sensitive to the friction moment. The aim is to know the proportion of the friction moment caused by each frictional source in the bearing’s total friction moment, which is helpful to optimize the bearing design to deduce the friction moment. In the model, the cage dynamic equations considering six degree-of-freedom and the balls dynamic equations considering two degree-of-freedom were solved. The good trends with different loads between the measured friction moments and computational results prove that the model under constant rate was validated. The computational results show that when the speed was set at 5 r/min, the bearing’s maximum total friction moment when oscillation occurred was obviously larger than that occurred at a constant rate. At the onset of each oscillatory motion, the proportion of the friction moment caused by cage in the bearing’s total friction moment was very high, and it increased with the increasing speed. The analyses of different cage thicknesses and different clearances between cage pocket and ball show that smaller thickness and clearance were preferred.

  5. Use, fate and ecological risks of antibiotics applied in tilapia cage farming in Thailand

    International Nuclear Information System (INIS)

    The use, environmental fate and ecological risks of antibiotics applied in tilapia cage farming were investigated in the Tha Chin and Mun rivers in Thailand. Information on antibiotic use was collected through interviewing 29 farmers, and the concentrations of the most commonly used antibiotics, oxytetracycline (OTC) and enrofloxacin (ENR), were monitored in river water and sediment samples. Moreover, we assessed the toxicity of OTC and ENR on tropical freshwater invertebrates and performed a risk assessment for aquatic ecosystems. All interviewed tilapia farmers reported to routinely use antibiotics. Peak water concentrations for OTC and ENR were 49 and 1.6 μg/L, respectively. Antibiotics were most frequently detected in sediments with concentrations up to 6908 μg/kg d.w. for OTC, and 2339 μg/kg d.w. for ENR. The results of this study indicate insignificant short-term risks for primary producers and invertebrates, but suggest that the studied aquaculture farms constitute an important source of antibiotic pollution. - Highlights: • First study assessing the risks of antibiotics applied in freshwater tilapia cages. • Ten antibiotics were reported to be used by tilapia cage farmers in two Thai rivers. • Peak oxytetracycline and enrofloxacin concentrations were in the order of μg/L. • Antibiotic concentrations in river sediments next to cages were up to several mg/kg. • Antibiotics are not posing a short-term risk for pelagic aquatic organisms. - Antibiotics applied in tilapia cage farming in Thailand are released into surrounding aquatic ecosystems and constitute an important source of environmental pollution

  6. Molecular Cage Impregnated Palladium Nanoparticles: Efficient, Additive-Free Heterogeneous Catalysts for Cyanation of Aryl Halides.

    Science.gov (United States)

    Mondal, Bijnaneswar; Acharyya, Koushik; Howlader, Prodip; Mukherjee, Partha Sarathi

    2016-02-10

    Two shape-persistent covalent cages (CC1(r) and CC2(r)) have been devised from triphenyl amine-based trialdehydes and cyclohexane diamine building blocks utilizing the dynamic imine chemistry followed by imine bond reduction. The cage compounds have been characterized by several spectroscopic techniques which suggest that CC1(r) and CC2(r) are [2+3] and [8+12] self-assembled architectures, respectively. These state-of-the-art molecules have a porous interior and stable aromatic backbone with multiple palladium binding sites to engineer the controlled synthesis and stabilization of ultrafine palladium nanoparticles (PdNPs). As-synthesized cage-embedded PdNPs have been characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), and powder X-ray diffraction (PXRD). Inductively coupled plasma optical emission spectrometry reveals that Pd@CC1(r) and Pd@CC2(r) have 40 and 25 wt% palladium loading, respectively. On the basis of TEM analysis, it has been estimated that as small as ∼1.8 nm PdNPs could be stabilized inside the CC1(r), while larger CC2(r) could stabilize ∼3.7 nm NPs. In contrast, reduction of palladium salts in the absence of the cages form structure less agglomerates. The well-dispersed cage-embedded NPs exhibit efficient catalytic performance in the cyanation of aryl halides under heterogeneous, additive-free condition. Moreover, these materials have excellent stability and recyclability without any agglomeration of PdNPs after several cycles. PMID:26771385

  7. High-temperature in situ crystallographic observation of reversible gas sorption in impermeable organic cages.

    Science.gov (United States)

    Baek, Seung Bin; Moon, Dohyun; Graf, Robert; Cho, Woo Jong; Park, Sung Woo; Yoon, Tae-Ung; Cho, Seung Joo; Hwang, In-Chul; Bae, Youn-Sang; Spiess, Hans W; Lee, Hee Cheon; Kim, Kwang S

    2015-11-17

    Crystallographic observation of adsorbed gas molecules is a highly difficult task due to their rapid motion. Here, we report the in situ single-crystal and synchrotron powder X-ray observations of reversible CO2 sorption processes in an apparently nonporous organic crystal under varying pressures at high temperatures. The host material is formed by hydrogen bond network between 1,3,5-tris-(4-carboxyphenyl)benzene (H3BTB) and N,N-dimethylformamide (DMF) and by π-π stacking between the H3BTB moieties. The material can be viewed as a well-ordered array of cages, which are tight packed with each other so that the cages are inaccessible from outside. Thus, the host is practically nonporous. Despite the absence of permanent pathways connecting the empty cages, they are permeable to CO2 at high temperatures due to thermally activated molecular gating, and the weakly confined CO2 molecules in the cages allow direct detection by in situ single-crystal X-ray diffraction at 323 K. Variable-temperature in situ synchrotron powder X-ray diffraction studies also show that the CO2 sorption is reversible and driven by temperature increase. Solid-state magic angle spinning NMR defines the interactions of CO2 with the organic framework and dynamic motion of CO2 in cages. The reversible sorption is attributed to the dynamic motion of the DMF molecules combined with the axial motions/angular fluctuations of CO2 (a series of transient opening/closing of compartments enabling CO2 molecule passage), as revealed from NMR and simulations. This temperature-driven transient molecular gating can store gaseous molecules in ordered arrays toward unique collective properties and release them for ready use. PMID:26578758

  8. Bulk Viscosity in Holographic Lifshitz Hydrodynamics

    CERN Document Server

    Hoyos, Carlos; Oz, Yaron

    2013-01-01

    We compute the bulk viscosity in holographic models dual to theories with Lifshitz scaling and/or hyperscaling violation, using a generalization of the bulk viscosity formula derived in arXiv:1103.1657 from the null focusing equation. We find that only a class of models with massive vector fields are truly Lifshitz scale invariant, and have a vanishing bulk viscosity. For other holographic models with scalars and/or massless vector fields we find a universal formula in terms of the dynamical exponent and the hyperscaling violation exponent.

  9. Bulk viscosity in holographic Lifshitz hydrodynamics

    OpenAIRE

    Carlos Hoyos; Bom Soo Kim; Yaron Oz

    2014-01-01

    We compute the bulk viscosity in holographic models dual to theories with Lifshitz scaling and/or hyperscaling violation, using a generalization of the bulk viscosity formula derived in arXiv:1103.1657 from the null focusing equation. We find that only a class of models with massive vector fields are truly Lifshitz scale invariant, and have a vanishing bulk viscosity. For other holographic models with scalars and/or massless vector fields we find a universal formula in terms of the dynamical ...

  10. Bulk viscosity in holographic Lifshitz hydrodynamics

    International Nuclear Information System (INIS)

    We compute the bulk viscosity in holographic models dual to theories with Lifshitz scaling and/or hyperscaling violation, using a generalization of the bulk viscosity formula derived in arXiv:1103.1657 from the null focusing equation. We find that only a class of models with massive vector fields are truly Lifshitz scale invariant, and have a vanishing bulk viscosity. For other holographic models with scalars and/or massless vector fields we find a universal formula in terms of the dynamical exponent and the hyperscaling violation exponent

  11. Bulk viscosity of hot and dense hadrons

    International Nuclear Information System (INIS)

    The bulk viscosity of hot and dense hadrons has been estimated within the framework of hadronic resonance gas model. We observe that the bulk viscosity to entropy ratio increases faster with temperature for higher μB. The magnitude of ζ is more at high μB. This results will have crucial importance for fire-ball produced at low energy nuclear collisions (FAIR, NICA). We note that the bulk to shear viscosity ratio remains above the bound set by AdS/CFT

  12. Population size, cage area, and dominance rank effects on productivity and well-being of laying hens.

    Science.gov (United States)

    Cunningham, D L; van Tienhoven, A; Gvaryahu, G

    1988-03-01

    The effect of two cage population sizes (four vs. six/cage) and two cage area treatments (316 cm2 vs. 406 cm2/bird) were compared in a nonconfounded design while maintaining feeder space constant (8.9 cm/bird) for egg production performances and behavioral and physiological indicators of well-being of laying hens. Egg production rates were determined for all members of each cage group (palpations at 48 to 50 wk) and on a cage group basis (20 to 60 wk). Heart weights, plasma corticosterone levels, durations of tonic immobility (TI), and plumage conditions were compared for top and bottom birds in the dominance ranks. Significant reductions in egg production were observed for low ranking hens in the high density (4 and 6/316-cm2) treatments. In addition, high ranking hens of the 6/316-cm2 treatment produced fewer eggs than high ranking hens in the 4/316-cm2 treatment. When high and low ranking individuals were housed in single-hen cages, egg production was improved relative to performances in the social environments. Heart weights of hens, as a percentage of body weight, were increased in the low ranking hens and for hens in the smaller cage size. Plasma corticosterone did not prove to be a useful indicator of well-being. Low ranking individuals had greater durations of TI but differences in feather condition were not detected. The results support the contention that appropriate population sizes and cage space allocations can be determined that will optimize the performance and welfare of layers in cage environments. PMID:3405919

  13. Biomechanical effects of polyaxial pedicle screw fixation on the lumbosacral segments with an anterior interbody cage support

    Directory of Open Access Journals (Sweden)

    Chen Hsiang-Ho

    2007-03-01

    Full Text Available Abstract Background Lumbosacral fusion is a relatively common procedure that is used in the management of an unstable spine. The anterior interbody cage has been involved to enhance the stability of a pedicle screw construct used at the lumbosacral junction. Biomechanical differences between polyaxial and monoaxial pedicle screws linked with various rod contours were investigated to analyze the respective effects on overall construct stiffness, cage strain, rod strain, and contact ratios at the vertebra-cage junction. Methods A synthetic model composed of two ultrahigh molecular weight polyethylene blocks was used with four titanium pedicle screws (two in each block and two rods fixation to build the spinal construct along with an anterior interbody cage support. For each pair of the construct fixed with polyaxial or monoaxial screws, the linked rods were set at four configurations to simulate 0°, 7°, 14°, and 21° lordosis on the sagittal plane, and a compressive load of 300 N was applied. Strain gauges were attached to the posterior surface of the cage and to the central area of the left connecting rod. Also, the contact area between the block and the cage was measured using prescale Fuji super low pressure film for compression, flexion, lateral bending and torsion tests. Results Our main findings in the experiments with an anterior interbody cage support are as follows: 1 large segmental lordosis can decrease the stiffness of monoaxial pedicle screws constructs; 2 polyaxial screws rather than monoaxial screws combined with the cage fixation provide higher compression and flexion stiffness in 21° segmental lordosis; 3 polyaxial screws enhance the contact surface of the cage in 21° segmental lordosis. Conclusion Polyaxial screws system used in conjunction with anterior cage support yields higher contact ratio, compression and flexion stiffness of spinal constructs than monoaxial screws system does in the same model when the spinal segment

  14. Technical specifications for the bulk shielding reactor

    International Nuclear Information System (INIS)

    This report provides information concerning the technical specifications for the Bulk Shielding Reactor. Areas covered include: safety limits and limiting safety settings; limiting conditions for operation; surveillance requirements; design features; administrative controls; and monitoring of airborne effluents. 10 refs

  15. The bulk radio expansion of Cassiopeia A

    International Nuclear Information System (INIS)

    Comparison, in the visibility plane, or radio observations of Cassiopeia A made at 151 MHz over a 2.3 yr interval indicates that the bulk of the radio emitting material has not been decelerated strongly

  16. Faecal bulking efficacy of Australasian breakfast cereals.

    Science.gov (United States)

    Monro, John A

    2002-01-01

    Faecal bulk may play an important role in preventing a range of disorders of the large bowel, but as yet there is little information available on the relative faecal bulking capacities of various foods. Breakfast cereals are often promoted as a good source of potential bulk for 'inner health' because they provide dietary fibre, but their relative abilities to provide faecal bulk per se have not been described. The faecal bulking efficacy of 28 representative Australasian breakfast cereals was therefore measured. A rat model developed for the purpose, and shown to give similar responses as humans to cereal fibres, was used to measure faecal bulking efficacy as increases in fully hydrated faecal weight/100 g diet, based on precise measurements of food intake, faecal dry matter output and faecal water-holding capacity (g water held without stress/g faecal dry matter). Compared to a baseline diet containing 50% sucrose, increments in hydrated faecal weight due to 50% breakfast cereal ranged from slightly negative (Cornflakes, -2 g/100 g diet) to about 80 g/100 g diet (San Bran). Most breakfast cereals increased hydrated faecal weight by between 10 and 20 g/100 g diet from a baseline of 21 +/- 1.5 g/100 g diet, but four products containing high levels of wheat bran had an exceptionally large impact on hydrated faecal weight (increment > 20 g/100 g diet), and the changes resulted more from relative changes in dry matter output than in faecal water retention/gram. However, as faecal water retention was about 2.5 g water/g faecal dry matter on average, increases in dry matter represented large increases in faecal water load. Faecal bulking indices (FBI) for most of the breakfast cereals were less than 20 (wheat bran = 100). The content of wheat bran equivalents for faecal bulk (WBE(fb)) in the breakfast cereals was calculated from FBI. Most breakfast cereals contributed, per serve, less than 10% of a theoretical daily reference value for faecal bulk (DRV(fb) = 63 WBE

  17. PHONON ECHOES IN BULK AND POWDERED MATERIALS

    OpenAIRE

    Kajimura, K.

    1981-01-01

    Experimental and theoretical studies of phonon echoes in bulk and powdered materials are reviewed. Phonon echoes have been observed in many materials such as bulk piezoelectric crystals, paramagnets, glasses, doped semiconductors, and piezoelectric, magnetic, and metallic powders, etc. The echoes arise from a time reversal of the phase, like spin echoes, of a primary pulsed acoustic excitation due to a second acoustic or rf pulse. The phase reversal occurs through the nonlinear interactions o...

  18. Orbital magnetization in insulators: Bulk versus surface

    Science.gov (United States)

    Bianco, Raffaello; Resta, Raffaele

    2016-05-01

    The orbital magnetic moment of a finite piece of matter is expressed in terms of the one-body density matrix as a simple trace. We address a macroscopic system, insulating in the bulk, and we show that its orbital moment is the sum of a bulk term and a surface term, both extensive. The latter only occurs when the transverse conductivity is nonzero and it is due to conducting surface states. Simulations on a model Hamiltonian validate our theory.

  19. An intrinsic mobility ceiling of Si bulk

    OpenAIRE

    Garcia-Castello, Nuria; Prades, Joan Daniel; Cirera, Albert

    2011-01-01

    We compute by Density Functional Theory-Non Equilibrium Green Functions Formalism (DFT-NEGFF) the conductance of bulk Si along different crystallographic directions. We find a ceiling value for the intrinsic mobility of bulk silicon of $8.4\\cdot10^6 cm^2/V\\cdot s$. We suggest that this result is related to the lowest effective mass of the $$ direction.

  20. Mercury and stable isotope signatures in caged marine fish and fish feeds

    Energy Technology Data Exchange (ETDEWEB)

    Onsanit, Sarayut; Chen, Min; Ke, Caihuan [State Key Laboratory for Marine Environmental Science, College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005 (China); Wang, Wen-Xiong, E-mail: wwang@ust.hk [State Key Laboratory for Marine Environmental Science, College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005 (China)

    2012-02-15

    Highlights: Black-Right-Pointing-Pointer Mercury concentrations in caged fish were closely related to Hg concentrations in fish feeds. Black-Right-Pointing-Pointer The trophic transfer factor of methylmercury was dependent on fish feeds, and was the highest for fish fed on pellet feeds. Black-Right-Pointing-Pointer Fish farming may be a good way of reducing the human exposure to Hg because Hg levels can be carefully controlled. - Abstract: Total mercury (THg) and methylmercury (MeHg) concentrations were determined in four species of marine caged carnivorous fish, one species of herbivorous fish and three types of fish feeds (dried pellet feed, forage fish and fish viscera), collected from five cage sites in the rural areas along Fujian coastline, China. For the carnivorous fish, the concentrations of THg and MeHg ranged from 0.03 to 0.31 {mu}g/g and from 0.02 to 0.30 {mu}g/g on wet weight basis, respectively. The concentrations were lower for the herbivorous fish with both within the range of 0.01-0.03 {mu}g/g. Out of the three tested fish feeds, tuna viscera contained the highest level of mercury (0.20 {mu}g/g THg and 0.13 {mu}g/g MeHg), with pellet feed containing the lowest level (0.05 {mu}g/g THg and 0.01 {mu}g/g MeHg). The calculated trophic transfer factor of MeHg was the highest (12-64) for fish fed on pellet feeds, and was the lowest for fish fed on tuna viscera. A significant relationship was found between Hg concentrations in caged fish and in fish feeds, thus Hg was primarily accumulated from the diet. Furthermore, the stable isotope {delta}{sup 15}N was positively correlated with the Hg concentration in two caged sites, indicating that {delta}{sup 15}N may be a suitable tool for tracking mercury in caged fish. We conclude that fish farming may be a good way of reducing the human exposure to Hg because mercury levels can be carefully controlled in such farming systems.

  1. Production performance, use of nest box, and external appearance of two strains of laying hens kept in conventional and enriched cages.

    Science.gov (United States)

    Onbaşılar, E E; Ünal, N; Erdem, E; Kocakaya, A; Yaranoğlu, B

    2015-04-01

    The aim of this study was to investigate the differences in production performance, use of nest box, and external appearance of 2 strains of laying hens kept in conventional and enriched cages. Lohmann Brown Classic (LB, n=532) and Lohmann LSL Classic (LW, n=532) hens were housed from 16 to 73 wk in either conventional cages or enriched cages. Enriched cages had a nesting area, scratch pad, perch, and nail shortener. Body weight (BW), hen-day egg production, egg weight, feed intake, feed conversion ratio (FCR), cracked and dirty eggs, use of nest box for lay, and external appearance were determined. Laying period influenced the hen-day egg production, egg weight, feed intake, and feed conversion ratio. Cage type affected the hen-day egg production and feed conversion ratio, while strain affected the egg weight, feed intake, and feed conversion ratio. Laying period×cage type and laying period×strain interactions affected egg production, egg weight, and feed conversion ratio. Both strains preferred to lay in the nest box. Percentages of cracked and dirty eggs of LW hens in enriched cages were higher than that in conventional cages. Most of the dirty eggs laid by both strains were found outside of the nest box. The LW hens laid more dirty eggs than the LB hens. Cage type and cage type×strain interaction were important for total feather score. Final claw length was affected by cage type, strain, and cage type×strain interaction. This study suggests that cage type, strain, and also cage type×strain and period×strain interactions should be considered when alternative housing systems are used. PMID:25667426

  2. Separation of rare gases and chiral molecules by selective binding in porous organic cages

    Science.gov (United States)

    Chen, Linjiang; Reiss, Paul S.; Chong, Samantha Y.; Holden, Daniel; Jelfs, Kim E.; Hasell, Tom; Little, Marc A.; Kewley, Adam; Briggs, Michael E.; Stephenson, Andrew; Thomas, K. Mark; Armstrong, Jayne A.; Bell, Jon; Busto, Jose; Noel, Raymond; Liu, Jian; Strachan, Denis M.; Thallapally, Praveen K.; Cooper, Andrew I.

    2014-10-01

    The separation of molecules with similar size and shape is an important technological challenge. For example, rare gases can pose either an economic opportunity or an environmental hazard and there is a need to separate these spherical molecules selectively at low concentrations in air. Likewise, chiral molecules are important building blocks for pharmaceuticals, but chiral enantiomers, by definition, have identical size and shape, and their separation can be challenging. Here we show that a porous organic cage molecule has unprecedented performance in the solid state for the separation of rare gases, such as krypton and xenon. The selectivity arises from a precise size match between the rare gas and the organic cage cavity, as predicted by molecular simulations. Breakthrough experiments demonstrate real practical potential for the separation of krypton, xenon and radon from air at concentrations of only a few parts per million. We also demonstrate selective binding of chiral organic molecules such as 1-phenylethanol, suggesting applications in enantioselective separation.

  3. Trapping of atomic hydrogen in octasilsesquioxane cages by glow discharge treatment

    International Nuclear Information System (INIS)

    Hydrogen atoms are trapped in octasilsesquioxane ((RSiO3/2)8, R = H, CH3, i-butyl, etc.) cages by electric discharge treatment. The yield of the trapped hydrogen was evaluated to be 1.3 x 10-4 of cage unit by using ESR spectroscopy for (CH3SiO3/2)8 discharged for 4 minutes at room temperature. To obtain a comparable yield of the trapped hydrogen by γ-rays (60Co) irradiation, an absorbed dose of ca. 300 kGy is required, taking two days or more in general. The discharge technique is simple and extremely efficient compared to the conventional method of γ-ray radiolysis. (author)

  4. Validation of an automated mite counter for Dermanyssus gallinae in experimental laying hen cages.

    Science.gov (United States)

    Mul, Monique F; van Riel, Johan W; Meerburg, Bastiaan G; Dicke, Marcel; George, David R; Groot Koerkamp, Peter W G

    2015-08-01

    For integrated pest management (IPM) programs to be maximally effective, monitoring of the growth and decline of the pest populations is essential. Here, we present the validation results of a new automated monitoring device for the poultry red mite (Dermanyssus gallinae), a serious pest in laying hen facilities world-wide. This monitoring device (called an "automated mite counter") was validated in experimental laying hen cages with live birds and a growing population of D. gallinae. This validation study resulted in 17 data points of 'number of mites counted' by the automated mite counter and the 'number of mites present' in the experimental laying hen cages. The study demonstrated that the automated mite counter was able to track the D. gallinae population effectively. A wider evaluation showed that this automated mite counter can become a useful tool in IPM of D. gallinae in laying hen facilities. PMID:26002308

  5. Cyclic Water Clusters in Tape-Like and Cage-Like Structures

    Directory of Open Access Journals (Sweden)

    Fuhou Lei

    2011-04-01

    Full Text Available Controlling the ratio of 2,2′-bpy to benzene-1,3,5-tricarboxylic acid produces two interesting complexes, namely [Co(2,2′-bpy3] (SO4 8.5H2O (1 and [Cu2(BTCA (2,2′-bpy4] (OH (2,2′-bpy0.5·14H2O (2 (H3BTCA = benzene-1,3,5-tricarboxylic acid, 2,2′-bpy = 2,2′-bipyridine. We report the structural evidence in the solid state of discrete lamellar water cluster conformations. These units are found to act as supramolecular glue in the aggregation of cobalt (II or copper (II complexes to give three dimensional cage-like networks through hydrogen-bonding. It is interesting that the structure of complex 1 contains a 3D negatively charged cage.

  6. Performance of Tambaqui (Colossoma macropomum) in Cages, under Different Percentage of Feeding

    OpenAIRE

    A. A. B. Pereira; P. R. Moeller; N. T. Vanderline; L. C. Q. Moura; P.S.A. Moreira

    2014-01-01

    The aim of this study was to evaluate the performance of different rate in percentage feeding of the productivity (Body weight (BW) and feed conversion (FC)) of juvenile tambaqui (Colossoma macropomum), with a total of 13500 animals, distributed in nine cages, with n = 1500 fish/cage, with three replicates in a period of four weeks. The animals were feed with   three treatments: treatment 1 (2% BW); treatment 2 ( 3% BW) and treatment 3 (4% BW), divided in two meals,  and feed  with commercial...

  7. Control System for Producing Electricity with Dual Stator Winding Cage-Rotor Induction Generator

    Directory of Open Access Journals (Sweden)

    Lucian Nicolae Tutelea

    2014-09-01

    Full Text Available This paper will present the key design equations and control design model of the Dual Stator Winding Cage-Rotor Induction Generator (DSWIG to achieve wide-speed-range operation with reduced capacity of the static power controller for low power wind or hydro applications. The proposed induction generator consists of a standard squirrel-cage rotor and a stator with two separate windings wound for a similar number of poles. Moreover, the system control strategy using the stator flux orientation is consequently proposed. The aim of the paper is to emphasize that the low speed induction generators with power electronic converters represent a realistic and useful solution for direct drive power applications.

  8. Pentagonal dodecahedron methane hydrate cage and methanol system—An ab initio study

    Indian Academy of Sciences (India)

    Snehanshu Pal; T K Kundu

    2013-03-01

    Density functional theory based studies have been performed to elucidate the role of methanol as an methane hydrate inhibitor. A methane hydrate pentagonal dodecahedron cage’s geometry optimization, natural bond orbital (NBO) analysis, Mullikan charge determination, electrostatic potential evaluation and vibrational frequency calculation with and without the presence of methanol using WB97XD/6-31++G(d,p) have been carried out. Calculated geometrical parameters and interaction energies indicate that methanol destabilizes pentagonal dodecahedron methane hydrate cage (1CH4@512) with and without the presence of sodium ion. NBO analysis and red shift of vibrational frequency reveal that hydrogen bond formation between methanol and water molecules of 1CH4@512 cage is favourable subsequently after breaking its original hydrogen bonded network.

  9. Introduced, Captive, Caged and Escaped Exotic and Native Bird Species in the Littoral Area of Lebanon

    International Nuclear Information System (INIS)

    Some introduced exotic bird species may cause damages to the ecosystem they are introduced to; others may have no effect or can be beneficial to humans and ecosystems.Whatever the case is, the exotic bird species remain an issue in Lebanon, especially that they are not given the appropriate priority at the national level. With the recent intentional or accidental introduction of exotic species,the problem is increasing and therefore necessitating comprehensive evaluation of the status and origin of these species in Lebanon.Since many of the introduced species are escapes from cages, it was necessary to also evaluate both status and origin of all caged birds in order to see whether they are introduced or native to the country. (author)

  10. Numerical Simulation of Dynamic Response of A Net Cage for Flatfish in Waves

    Institute of Scientific and Technical Information of China (English)

    桂福坤; 赵云鹏; 许条建; 关长涛

    2014-01-01

    A numerical model of flatfish cage is built based on the lumped mass method and the principle of rigid body kinematics. To validate the numerical model, a series of physical model tests are conducted in the wave flume. The numerical results correspond well with the data sets from physical model test. The effect of weight of bottom frame, height of fish net and net shape on motion responses of fish cage and tension force on mooring lines is then analyzed. The results indicate that the vertical displacements of float collar and bottom frame decrease with the increase in the weight of bottom frame; the maximum tension force on mooring lines increases with the increasing weight of bottom frame. The inclination angles of float collar and bottom frame decrease with the increasing net height; the maximum tension force increases obviously with the increase of net height.

  11. Effect of Caging and Swimmer Bars on Flexural Response of RC Deep Beams

    Directory of Open Access Journals (Sweden)

    Revathy S

    2015-08-01

    Full Text Available Beams with shear span to depth ratio (a/d less than or equal to 2 are considered as deep beams. They have wide applications in pile caps, water tanks, shear walls, corbels etc. Their strength is controlled by shear. Swimmer bars are small inclined bars, whose both ends are bent horizontally and welded to both top and bottom flexural reinforcement. Swimmer bars forming a plane crack interceptor system is effective in carrying shear. Also, a reinforcement caging provided at the centre of a simply supported beam is supposed to enhance its flexural capacity. In this study, an experimental investigation on the flexural response of deep beams reinforced with caging and swimmer bars is done. Various parameters like ultimate load, deflection and failure modes of different reinforcement patterns are studied.

  12. Fabrication of CuO nanoparticle interlinked microsphere cages by solution method

    Directory of Open Access Journals (Sweden)

    Tian HuYong

    2007-01-01

    Full Text Available AbstractHere we report a very simple method to convert conventional CuO powders to nanoparticle interlinked microsphere cages by solution method. CuO is dissolved into aqueous ammonia, and the solution is diluted by alcohol and dip coating onto a glass substrate. Drying at 80 °C, the nanostructures with bunchy nanoparticles of Cu(OH2can be formed. After the substrate immerges into the solution and we vaporize the solution, hollow microspheres can be formed onto the substrate. There are three phases in the as-prepared samples, monoclinic tenorite CuO, orthorhombic Cu(OH2, and monoclinic carbonatodiamminecopper(II (Cu(NH32CO3. After annealing at 150 °C, the products convert to CuO completely. At annealing temperature above 350 °C, the hollow microspheres became nanoparticle interlinked cages.

  13. Parasitic diseases in marine cage culture--an example of experimental evolution of parasites?

    Science.gov (United States)

    Nowak, Barbara F

    2007-05-01

    Rapid development of fish culture in marine cages has been associated with an emergence of parasitic diseases. There is a general trend to an increase in infections with ectoparasites with direct life cycles and a reduced diversity of parasites in aquaculture. Some mariculture creates conditions that are similar to serial passage experiments, which are used to study adaptation during experimental evolution of pathogens. In particular, increased density of fish, repeated introduction of naive hosts, homogenous host populations, fast growth and a potential decrease in genetic diversity are attributes of both aquaculture and serial passage experiments. Some free-living organisms, for example Neoparamoeba spp. and Uronema spp. parasitise fish in culture, but have not been reported from wild populations. Farming fish in marine cages can increase the risk of outbreaks of parasitic diseases, including those caused by opportunistic parasites. However, aquaculture has the potential to control parasitic diseases through selective breeding, vaccination and general fish health management. PMID:17316650

  14. Stability of gold cages (Au16 and Au17) at finite temperature

    Indian Academy of Sciences (India)

    Prachi Chandrachud; Kavita Joshi; Sailaja Krishnamurty; D G Kanhere

    2009-05-01

    We have employed ab initio molecular dynamics to investigate the stability of the smallest gold cages, namely Au16 and Au17, at finite temperatures. First, we obtain the ground state structure along with at least 50 distinct isomers for both the clusters. This is followed by the finite temperature simulations of these clusters. Each cluster is maintained at 12 different temperatures for a time period of at least 150 ps. Thus, the total simulation time is of the order of 2.4 ns for each cluster. We observe that the cages are stable at least up to 850 K. Although both clusters melt around the same temperature, i.e. around 900 K, Au17 shows a peak in the heat capacity curve in contrast to the broad peak seen for Au16.

  15. Novel rotating characteristics of a squirrel-cage-type HTS induction/synchronous motor

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, T; Ogama, Y; Miyake, H; Nagao, K; Nishimura, T [Department of Electrical Engineering, Graduate School of Engineering, Kyoto University, Kyoto-Daigaku Katsura 1, Nishikyo-Ku, Kyoto 615-8510 (Japan)

    2007-10-15

    This paper describes the rotating characteristics of a high-T{sub c} superconducting induction/synchronous motor, which possesses both asynchronous and synchronous torques even though its structure is exactly the same as the squirrel-cage-type induction motor. Two kinds of Bi-2223/Ag multifilamentary tapes were utilized for the secondary windings. A commercialized motor (1.5 kW) was subjected to this study. A conventional (normal conducting) stator (three-phase, four-pole) was directly utilized, and only the squirrel-cage windings were replaced with the superconducting tapes. The tests were performed after the fabricated motor was immersed in liquid nitrogen. The operating temperature was also varied by pumping out the liquid nitrogen. It is shown that the motor is successfully synchronized for the temperature range from 65 to 77 K. Detailed discussions for such novel rotating characteristics are reported based on the electrical equivalent circuit.

  16. Theoretical prediction for the (AlN)12 fullerene-like cage-based nanomaterials

    International Nuclear Information System (INIS)

    We have performed ab initio calculations on the stability and structural and electronic properties of the fullerene-like cage (AlN)n (n = 12) and the polymerized dimers and nanowires obtained from it. We found that the (AlN)12-(AlN)12 dimers and aluminum nitride (AlN)12-based nanowires polymerized from the (AlN)12 cage are more stable than (AlN)12. The optimized configurations of the nanowires are especially regular and exhibit an interesting dumbbell-shaped chain structure. We also calculated the electronic structures of all the constructed nanostructures. The two novel (AlN)12-based aluminum nitride nanowires have band gaps of 2.844 and 3.085 eV, respectively, implying that they are both wide-gap semiconductors and may be promising candidates for nanotechnology

  17. Novel rotating characteristics of a squirrel-cage-type HTS induction/synchronous motor

    International Nuclear Information System (INIS)

    This paper describes the rotating characteristics of a high-Tc superconducting induction/synchronous motor, which possesses both asynchronous and synchronous torques even though its structure is exactly the same as the squirrel-cage-type induction motor. Two kinds of Bi-2223/Ag multifilamentary tapes were utilized for the secondary windings. A commercialized motor (1.5 kW) was subjected to this study. A conventional (normal conducting) stator (three-phase, four-pole) was directly utilized, and only the squirrel-cage windings were replaced with the superconducting tapes. The tests were performed after the fabricated motor was immersed in liquid nitrogen. The operating temperature was also varied by pumping out the liquid nitrogen. It is shown that the motor is successfully synchronized for the temperature range from 65 to 77 K. Detailed discussions for such novel rotating characteristics are reported based on the electrical equivalent circuit

  18. Theoretical study of methanol as inhibitor and cyclopentane as stabilizer of dodecahedron methane hydrate cage

    Science.gov (United States)

    Pal, Snehanshu; Kundu, T. K.

    2015-02-01

    Density Functional Theory (DFT) based simulations have been performed to explain the role of methanol as an inhibitor and the role of cyclopentane as a promoter for methane hydrate. Interaction energy, Mullikan charges and electrostatic potential parameters for combined system of methanol and dodecahedron methane hydrate as well as cyclopentane and dodecahedron (512) methane hydrate cage are calculated using B3LYP functional (with and without dispersion function) and 6-31G(d) basis set. Methane hydrate formation inhibition by methanol and methane hydrate stabilization by cyclopentane is critically analyzed based on electrostatic potential and Mullikan charge. It is observed that hydrogen bond between water molecules of clathrate 512 cages become stronger in presence of cyclopentane and weaker in presence of methanol. It is also found that methanol breaks some hydrogen bonds of water molecules.

  19. Exposure of the superior gluteal neurovascular bundle for the safe application of acetabular reinforcement cages in complex revisions.

    Science.gov (United States)

    Smitham, Peter J; Kosuge, Dennis; Howie, Donald W; Solomon, Lucian B

    2016-05-16

    The posterior approach to the hip is the most common extensile approach used, however exposure is limited superiorly by the superior gluteal neurovascular bundle (SGNB). The extra-pelvic course of the SGNB demonstrates variability between individuals, occasionally located only 1 cm from the acetabular rim. In complex acetabular reconstructions where the application of a reinforcement cage maybe required protecting the SGNB is challenging. The flanges of these cages are designed to sit on the ilium superior to the acetabular rim and to receive screws for fixation. The application of such cages may result in iatrogenic injury to the SGNB by way of forceful retraction or entrapment. We describe a technique that involves exposure and release of the SGNB such that the flanges of cage constructs may be safely applied. PMID:27079287

  20. Flash and smash: rapid freezing of muscle fibers activated by photolysis of caged ATP.

    OpenAIRE

    Hirose, K.; Lenart, T D; Murray, J.M.; Franzini-Armstrong, C; Goldman, Y E

    1993-01-01

    A new approach was used to study transient structural states of cross-bridges during activation of muscle fibers. Rabbit skinned muscle fibers were rapidly and synchronously activated from the rigor state by photolysis of caged ATP in the presence of Ca2+. At several different times during the switch from rigor to fully active tension development, the fibers were rapidly frozen on a liquid helium-cooled metal block, freeze-substituted, and examined in an electron microscope. The limits of str...

  1. Small Cages with Insect Couples Provide a Simple Method for a Preliminary Assessment of Mating Disruption

    OpenAIRE

    Françoise Briand; Guerin, Patrick M.; Pierre-Joseph Charmillot; Patrik Kehrli

    2012-01-01

    Mating disruption by sex pheromones is a sustainable, effective and widely used pest management scheme. A drawback of this technique is its challenging assessment of effectiveness in the field (e.g., spatial scale, pest density). The aim of this work was to facilitate the evaluation of field-deployed pheromone dispensers. We tested the suitability of small insect field cages for a pre-evaluation of the impact of sex pheromones on mating using the grape moths Eupoecilia ambiguella and Lobesia ...

  2. Cathodic cage nitriding of AISI 409 ferritic stainless steel with the addition of CH4

    Directory of Open Access Journals (Sweden)

    Rômulo Ribeiro Magalhães de Sousa

    2012-04-01

    Full Text Available AISI 409 ferritic stainless steel samples were nitrided using the cathodic cage plasma nitriding technique (CCPN, with the addition of methane to reduce chromium precipitation, increase hardness and wear resistance and reduce the presence of nitrides when compared to plasma carbonitriding. Microhardness profiles and X-Ray analysis confirm the formation of a very hard layer containing mainly ε-Fe3N and expanded ferrite phases.

  3. Cathodic cage nitriding of AISI 409 ferritic stainless steel with the addition of CH4

    OpenAIRE

    Rômulo Ribeiro Magalhães de Sousa; Francisco Odolberto de Araújo; José Alzamir Pereira da Costa; Antonio Maia de Oliveira; Mineia Sampaio Melo; Clodomiro Alves Junior

    2012-01-01

    AISI 409 ferritic stainless steel samples were nitrided using the cathodic cage plasma nitriding technique (CCPN), with the addition of methane to reduce chromium precipitation, increase hardness and wear resistance and reduce the presence of nitrides when compared to plasma carbonitriding. Microhardness profiles and X-Ray analysis confirm the formation of a very hard layer containing mainly ε-Fe3N and expanded ferrite phases.

  4. Template-directed synthesis of nets based upon octahemioctahedral cages that encapsulate catalytically active metalloporphyrins

    KAUST Repository

    Zhang, ZhenJie

    2012-01-18

    meso-Tetra(N-methyl-4-pyridyl)porphine tetratosylate (TMPyP) templates the synthesis of six new metal-organic materials by the reaction of benzene-1,3,5-tricarboxylate with transition metals, five of which exhibit HKUST-1 or tbo topology (M = Fe, Mn, Co, Ni, Mg). The resulting materials, porph@MOMs, selectively encapsulate the corresponding metalloporphyrins in octahemioctahedral cages and can serve as size-selective heterogeneous catalysts for oxidation of olefins. © 2011 American Chemical Society.

  5. ‘Clickable’ Polymer-Caged Nanobins as a Modular Drug Delivery Platform

    OpenAIRE

    Lee, Sang-Min; Chen, Haimei; O'Halloran, Thomas V.; Nguyen, SonBinh T.

    2009-01-01

    Modularly clickable polymer-caged nanobins (PCNs) were prepared from liposome templates using a drop-in cholesterol-modified poly(acrylic acid) reagent followed by crosslinking with alkyne-functionalized diamine linker that can allow for the conjugation of azido-modified targeting ligands via click ligation. These PCNs possess pH-responsive characteristics that can be used to trigger the release of encapsulated doxorubicin (DXR) payload inside the liposomal core under mild acidic conditions. ...

  6. Endotoxin concentration in poultry houses for laying hens kept in cages or in alternative housing systems

    OpenAIRE

    Huneau-Salaün, Adeline; Le Bouquin, Sophie; Bex-Capelle, Valérie; Huonnic, Didier; Balaine, Loïc; Guillam, Marie-Thérèse; Squizani, Fabrice; Ségala, Claire; Michel, Virginie

    2011-01-01

    Abstract 1. Endotoxins as components of organic dust may have adverse effects on the respiratory health of workers in poultry buildings. The move towards more welfare-friendly housing systems for layers may increase worker exposure to air contaminants due to the use of litter. 2. The endotoxin concentrations in the inhalable fraction of airborne dust (below 100 ?m) from cage and alternative system henhouses (on-floor, free range and aviaries) were compared under both experiment...

  7. Cage rattling does not correlate with the local geometry in molecular liquids

    OpenAIRE

    Bernini, S.; Puosi, F.; Leporini, D.

    2016-01-01

    Molecular-dynamics simulations of a liquid of short linear molecules have been performed to investigate the correlation between the particle dynamics in the cage of the neighbors and the local geometry. The latter is characterized in terms of the size and the asphericity of the Voronoi polyhedra. The correlation is found to be poor. In particular, in spite of the different Voronoi volume around the end and the inner monomers of a molecule, all the monomers exhibit coinciding displacement dist...

  8. Validation of an automated mite counter for Dermanyssus gallinae in experimental laying hen cages

    OpenAIRE

    Mul, Monique; van Riel, Johan; Meerburg, Bastiaan; Dicke, Marcel; George, David; Groot Koerkamp, Peter

    2015-01-01

    For integrated pest management (IPM) programs to be maximally effective, monitoring of the growth and decline of the pest populations is essential. Here, we present the validation results of a new automated monitoring device for the poultry red mite (Dermanyssus gallinae), a serious pest in laying hen facilities world-wide. This monitoring device (called an “automated mite counter”) was validated in experimental laying hen cages with live birds and a growing population of D. gallinae. This va...

  9. Foraging and nesting behavior of Osmia lignaria (Hymenoptera: Megachilidae) in the presence of fungicides: cage studies.

    Science.gov (United States)

    Ladurner, E; Bosch, J; Kemp, W P; Maini, S

    2008-06-01

    During orchard pollination studies in California, we observed dramatic changes in nesting and foraging behavior of Osmia lignaria Say (Hymenoptera: Megachilidae) after sprays with tank mixtures containing fungicides. A characteristic pattern of postspray events observed includes erratic behavior and interrupted foraging and nesting activity for several days. In an effort to determine whether fungicidal sprays were disruptive to bee foraging and thus to pollination, we exposed O. lignaria females nesting in field cages planted with lacy scorpionweed, Phacelia tanacetifolia Benth (Hydrophyllaceae), to selected spray mixtures normally encountered in California orchard production systems: iprodione (Rovral), propiconazole (Orbit), benomyl (Benlate), and captan (Captan 50 WP); the surfactant Dyne-Amic, alone and mixed with Rovral; and the tank mixture IDB (Rovral + Dyne-Amic + the foliar fertilizer Bayfolan Plus). An additional cage sprayed with an equal volume of water acted as control, and a cage sprayed with the insecticide dimethoate as a toxic standard. For each female O. lignaria, we recorded time spent inside the nest depositing pollen-nectar loads, foraging time, cell production rate, and survival. All females in the dimethoate treatment died postspray + 1 d. Before death, some of these females behaved similarly to our previous orchard observations. A high proportion of females in the IDB cage were inactive for a few hours before resuming normal foraging and nesting activity. No lethal or behavioral effects were found for any of the other compounds or mixtures tested. Our results indicate that the fungicide applications that we tested are compatible with the use of O. lignaria as an orchard pollinator. PMID:18613561

  10. Aharonov-Bohm photonic cages in waveguide and coupled resonator lattices by synthetic magnetic fields

    OpenAIRE

    Longhi, Stefano

    2014-01-01

    We suggest a method for trapping photons in quasi one-dimensional waveguide or coupled-resonator lattices, which is based on an optical analogue of the Aharonov-Bohm cages for charged particles. Light trapping results from a destructive interference of Aharonov-Bohm type induced by a synthetic magnetic field, which is realized by periodic modulation of the waveguide/resonator propagation constants/resonances.

  11. Aharonov-Bohm photonic cages in waveguide and coupled resonator lattices by synthetic magnetic fields.

    Science.gov (United States)

    Longhi, Stefano

    2014-10-15

    We suggest a method for trapping photons in quasi-one-dimensional waveguide or coupled-resonator lattices, which is based on an optical analogue of the Aharonov-Bohm cages for charged particles. Light trapping results from a destructive interference of Aharonov-Bohm type induced by a synthetic magnetic field, which is realized by periodic modulation of the waveguide/resonator propagation constants/resonances. PMID:25361112

  12. Bisphenol A is released from used polycarbonate animal cages into water at room temperature.

    OpenAIRE

    Howdeshell, Kembra L.; Peterman, Paul H; Judy, Barbara M.; Taylor, Julia A.; Orazio, Carl E; Rachel L. Ruhlen; vom Saal, Frederick S.; Welshons, Wade V.

    2003-01-01

    Bisphenol A (BPA) is a monomer with estrogenic activity that is used in the production of food packaging, dental sealants, polycarbonate plastic, and many other products. The monomer has previously been reported to hydrolyze and leach from these products under high heat and alkaline conditions, and the amount of leaching increases as a function of use. We examined whether new and used polycarbonate animal cages passively release bioactive levels of BPA into water at room temperature and neutr...

  13. Confocal Bioluminescence Imaging for Living Tissues with a Caged Substrate of Luciferin.

    Science.gov (United States)

    Hattori, Mitsuru; Kawamura, Genki; Kojima, Ryosuke; Kamiya, Mako; Urano, Yasuteru; Ozawa, Takeaki

    2016-06-21

    Fluorescence imaging can elucidate morphological organization and coordinal networks, but its background luminescence degrades the image contrast. Our confocal bioluminescence imaging system uses a luciferase caged substrate, with light passing through multipinhole arrays, causing bioluminescence at a focal plane. After a charge-coupled device camera captures luminescence, the imaging system acquires confocal images of multilayered cells with depth information, supporting quantitative analysis of spatial cellular localization in living tissues. PMID:27216493

  14. Modeling and control of squirrel cage induction generator with full power converter applied to windmills

    OpenAIRE

    Dominguez Garcia, Jose Luis

    2009-01-01

    The project aims to develop a dynamic model, of a generation system of electrical energy with a variable speed wind turbine using a squirrel cage induction generator which is connected to the grid by a back to back frequency converter, for testing purposes. In the project has been done an analysis of the mathematical equations of the whole system, separating the mechanical system (turbine and gearbox) and the electrical (generator and converter). We study the control design ...

  15. Diagnosis of Wind Energy System Faults Part I : Modeling of the Squirrel Cage Induction Generator

    OpenAIRE

    Lahcène Noureddine; Omar Touhami

    2015-01-01

    Generating electrical power from wind energy is becoming increasingly important throughout the world. This fast development has attracted many researchers and electrical engineers to work on this field. The authors develop a dynamic model of the squirrel cage induction generator exists usually on wind energy systems, for the diagnosis of broken rotor bars defects from an approach of magnetically coupled multiple circuits. The generalized model is established on the base of mathematical recurr...

  16. An environmental study of the use of steel slag aggregate in gabion cages

    OpenAIRE

    Richter, Tanya Brigitte

    2013-01-01

    The growing tendency of sustainable building and development is transforming the way in which construction projects are faced. These changes are saving the natural environment, as well as, minimising the quantity of industrial waste. In line with this initiative, the following project studies the potential recovery of Electric Arc Furnace Slag and its use as material fill in gabion cages. From a sustainability point of view, the recovery of steel slag is positive from all perspectives. (a) E...

  17. A chemist and biologist talk to each other about caged neurotransmitters

    OpenAIRE

    Ellis-Davies, Graham C. R.

    2013-01-01

    Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative develo...

  18. The Effect of the PEEK Cage on the Cervical Lordosis in Patients Undergoing Anterior Cervical Discectomy

    Directory of Open Access Journals (Sweden)

    Salih Gulsen

    2015-03-01

    CONCLUSION: We achieved better cervical lordotic angles at the postoperative period by implanting one-level, two-level, three-level or four-level PEEK cage filled with demineralized bone matrix. Also, the causes of cervical root and or medulla spinalis impingement were different in group1 and 2. While extruded cervical disc impingement was the first pathology in group 1, osteophyte formation was the first pathology in group 2.

  19. Population genetic structure of Ascaridia galli re-emerging in non-caged laying hens

    OpenAIRE

    Höglund Johan; Morrison David A; Engström Annie; Nejsum Peter; Jansson Désirée S

    2012-01-01

    Abstract Background The poultry roundworm Ascaridia galli has reappeared in hens kept for egg production in Sweden after having been almost absent a decade ago. Today this is a frequent intestinal nematode parasite in non-caged laying hens. The aim of this study was to investigate the genetic diversity (Fst) in A. galli collected from different poultry production sites in southern Sweden, to identify possible common routes of colonization. Methods Adult parasites (n = 153) from 10 farms, incl...

  20. Experimental practices of music and philosophy in John Cage and Gilles Deleuze

    OpenAIRE

    Campbell, Iain

    2015-01-01

    In this thesis we construct a critical encounter between the composer John Cage and the philosopher Gilles Deleuze. This encounter circulates through a constellation of problems found across and between mid-twentieth century musical, artistic, and philosophical practices, the central focus for our line of enquiry being the concept of experimentation. We emphasize the production of a method of experimentation through a practice historically situated with regards to the traditions of the respec...

  1. "Caged calcium" in Aplysia pacemaker neurons. Characterization of calcium-activated potassium and nonspecific cation currents

    OpenAIRE

    1989-01-01

    We have studied calcium-activated potassium current, IK(Ca), and calcium-activated nonspecific cation current, INS(Ca), in Aplysia bursting pacemaker neurons, using photolysis of a calcium chelator (nitr-5 or nitr-7) to release "caged calcium" intracellularly. A computer model of nitr photolysis, multiple buffer equilibration, and active calcium extrusion was developed to predict volume-average and front-surface calcium concentration transients. Changes in arsenazo III absorbance were used to...

  2. cagE as a biomarker of the pathogenicity of Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    Ivy Bastos Ramis

    2013-04-01

    Full Text Available Introduction Helicobacter pylori infection is associated with gastro-duodenal diseases. Genes related to pathogenicity have been described for H. pylori and some of them appear to be associated with more severe clinical outcomes of the infection. The present study investigates the role of cagE as a pathogenicity biomarker of H. pylori compare it to cagA, vacA, iceA and babA2 genes and correlate with endoscopic diagnoses. Methods Were collected biopsy samples of 144 dyspeptic patients at the Hospital of the Federal University of Rio Grande, Rio Grande do Sul, Brazil. After collection, the samples were sent for histological examination, DNA extraction and detection of all putative pathogenicity genes by PCR. Results Of the 144 patients undergoing endoscopy, 57 (39.6% presented H. pylori by histological examination and PCR by detection of the ureA gene. Based on the endoscopic diagnoses, 45.6% (26/57 of the patients had erosive gastritis, while 54.4% (31/57 had enanthematous gastritis. The genes cagA, cagE, vacAs1/m1, vacAs1/m2 and iceA1 were related to erosive gastritis, while the genes vacAs2/m2, iceA2 and babA2 were associated to enanthematous gastritis. We found a statistically significant association between the presence of cagE and the endoscopic diagnosis. However, we detect no statistically significant association between the endoscopic diagnosis and the presence of cagA, vacA, iceA and babA2, although a biological association has been suggested. Conclusions Thus, cagE could be a risk biomarker for gastric lesions and may contribute to a better evaluation of the H. pylori pathogenic potential and to the prognosis of infection evolution in the gastric mucosa.

  3. Check list of the parasitofauna in Adriatic sea cage-reared fish

    OpenAIRE

    Mladineo Ivona

    2006-01-01

    Along with the fast development of aquaculture in the Mediterranean, a number of emerging parasitic diseases was observed in cage-reared fish, which in confined rearing conditions induced mortality or/and indirect economical losses related to suppressed growth. The trend of diversification of aquaculture products and the introduction of new fish species in the rearing system, helped the introduction of new parasitic pathogens along with their host in the new environment. The process resulted ...

  4. Enhanced cooperativity below the caging temperature of glass-forming liquids

    OpenAIRE

    Erwin, B. M.; Colby, R. H.; Kamath, S. Y.; Kumar, S K

    2004-01-01

    The utility of a cooperative length scale for describing the dynamics of small molecule glass-formers is shown. Molecular Dynamics and Monte Carlo simulations reveal a distribution of cooperatively moving fractal events below the temperature Ta at which dynamics become caged. Guided by these results, four straightforward methods emerge to recognize Ta in experimental data and quantify the length scale that grows on cooling below Ta. This length scale is consistent with 4-D NMR experiments whi...

  5. Boron cage compound materials and composites for shielding and absorbing neutrons

    Science.gov (United States)

    Bowen, III, Daniel E; Eastwood, Eric A

    2014-03-04

    Boron cage compound-containing materials for shielding and absorbing neutrons. The materials include BCC-containing composites and compounds. BCC-containing compounds comprise a host polymer and a BCC attached thereto. BCC-containing composites comprise a mixture of a polymer matrix and a BCC filler. The BCC-containing materials can be used to form numerous articles of manufacture for shielding and absorbing neutrons.

  6. Enhancement Effect of Sea Urchin Grow-out Cages in Lucero, Bolinao, Pangasinan

    OpenAIRE

    Maria Celia Defrance Malay; Helen Grace Bangi; Marie Antonette Juinio-Meñez

    2000-01-01

    A preliminary study was conducted on the environmental impact of sea urchin (Tripneustes gratilla Linnaeas) grow-out culture in Lucero, Bolinao, Pangasinan. It was hypothesized that the feces generated by the caged urchins (~6,000 individuals at any one time) might cause localised sediment organic enrichment and subsequent shifts in benthic faunal communities. Results from preliminary surveys conducted in April and August of 1999 indicated minimal impact of sea urchin grow-out culture on the ...

  7. The Effect of the PEEK Cage on the Cervical Lordosis in Patients Undergoing Anterior Cervical Discectomy

    OpenAIRE

    Salih Gulsen

    2015-01-01

    BACKGROUND: Loss of cervical lordosis is a significant factor in the development of degeneration of the spine with aging. This degenerative changings of the cervical spine would cause pressure effect on the cervical root and/or medulla spinalis. AIM: Our goal is to understand the effect of the PEEK cage on cervical lordosis in the early postoperative period. Also, to interpret the effects of one- level, two- level, three-level and four- level disc pathologies on cervical lordosis. MAT...

  8. Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation†

    Science.gov (United States)

    Zhao, Jun; Gover, Tony D.; Muralidharan, Sukumaran; Auston, Darryl A.; Weinreich, Daniel; Kao, Joseph P. Y.

    2008-01-01

    Nociceptive neurons in the peripheral nervous system detect noxious stimuli and report the information to the central nervous system. Most nociceptive neurons express the vanilloid receptor, TRPV1, a non-selective cation channel gated by vanilloid ligands such as capsaicin, the pungent essence of chili peppers. Here, we report the synthesis and biological application of two caged vanilloids—biologically inert precursors that, when photolyzed, release bioactive vanilloid ligands. The two caged vanilloids, Nb-VNA and Nv-VNA, are photoreleased with quantum efficiency of 0.13 and 0.041, respectively. Under flash photolysis conditions, photorelease of Nb-VNA and Nv-VNA is 95% complete in ∼40 μs and ∼125 μs, respectively. Through 1-photon excitation with ultraviolet light (360 nm), or 2-photon excitation with red light (720 nm), the caged vanilloids can be photoreleased in situ to activate TRPV1 receptors on nociceptive neurons. The consequent increase in intracellular free Ca2+ concentration ([Ca2+]i) can be visualized by laser-scanning confocal imaging of neurons loaded with the fluorescent Ca2+ indicator, fluo-3. Stimulation results from TRPV1 receptor activation, because the response is blocked by capsazepine, a selective TRPV1 antagonist. In Ca2+-free extracellular medium, photoreleased vanilloid can still elevate [Ca2+]i, which suggests that TRPV1 receptors also reside on endomembranes in neurons and can mediate Ca2+ release from intracellular stores. Notably, whole-cell voltage clamp measurements showed that flash photorelease of vanilloid can activate TRPV1 channels in < 4 msec at 22°C. In combination with 1- or 2-photon excitation, caged vanilloids are a powerful tool for probing morphologically distinct structures of nociceptive sensory neurons with high spatial and temporal precision. PMID:16605259

  9. Sublethal effects in caged rainbow trout during remedial activities in Lake Jaernsjoen

    Energy Technology Data Exchange (ETDEWEB)

    Blom, S.; Foerlin, L. [Goeteborg Univ. (Sweden). Dept. of Zoophysiology; Norrgren, L. [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Faculty of Veterinary Medicine, Dept. of Pathology

    1998-08-01

    Caging juvenile rainbow trout in the PCB polluted Lake Jaernsjoen in 1991 prior to remediation resulted in induction of liver ethoxyresorufin-O-deethylase (EROD) activity, liver lesions, skin lesions and fin erosions, all of which can be caused by subchronic exposure to PCB. During the remediation in 1993 and 1994, pronounced induction of the liver EROD, bile-duct proliferation and a relatively high incidence of necrotic hepatocytes were seen in the rainbow trout caged in Lake Jaernsjoen. The histopathological damage noted in the liver was reflected in changes in plasma ASAT activities. In 1996, two years after the remedial activities, the EROD activity was still slightly induced in caged rainbow trout in Jaernsjoen, but the fish showed no sign of histopathological changes. In addition, the liver EROD activity was induced in some sites downstream of Jaernsjoen. These results indicate a downstream transport of contaminants following the remedial action Special issue. The Jaernsjoen project, Sweden. Remediation of PCB-contaminated sediments. 50 refs, 4 figs, 6 tabs

  10. Survey of prevalence and control of ectoparasites in caged poultry in China.

    Science.gov (United States)

    Wang, F F; Wang, M; Xu, F R; Liang, D M; Pan, B L

    2010-12-11

    To investigate the prevalence and control of ectoparasites in China, 1200 questionnaires were delivered to caged commercial layer or parent hen keepers. Of the 860 respondents, 785 (91.3 per cent) claimed they found suspected ectoparasites in their birds and 833 samples were received. Ectoparasites of the species Dermanyssus gallinae, Ornithonyssus sylviarum or Menacanthuss stramineus were found in 736 (88.4 per cent) samples. For caged commercial layers, D gallinae was the most common ectoparasite (64.1 per cent). For caged parent hens, O sylviarum was the most common ectoparasite (46.9 per cent). Most bird keepers (95.0 per cent of commercial layer keepers and 74.9 per cent of parent hen keepers) used pyrethroids, organophosphates or other insecticides or acaricides to control ectoparasites. However, 34.6 per cent of layer keepers and 25.7 per cent of parent hen keepers did not re-treat their birds with insecticides or acaricides within two weeks after the first treatment. Sanitation procedures, including cleaning, washing and disinfection, were conducted in empty houses between flocks and on most commercial layer farms and parent hen farms. However, insecticides or acaricides were used in empty houses between flocks only in 24.8 per cent of commercial layer farms and in 36.1 per cent of parent hen farms. PMID:21262694

  11. Stocking densities of juvenile Brycon orthotaenia: production parameters and economic benefits in net cages

    Directory of Open Access Journals (Sweden)

    Aline de Assis Lago

    2014-07-01

    Full Text Available Developing a rearing technology requires the determination of the optimum stocking density. This study aimed to determine the best stocking density for Brycon orthotaenia juveniles grown in net cages, during the rearing phase. The research was conducted at the Experimental Farm of EPAMIG, in Felixlândia, Minas Gerais State, in the Três Marias Reservoir. 9,000 fingerlings were distributed into 12 net cages, 2 m3each, according to a completely randomized design with three replications and four different stocking densities (150, 300, 450, 600 fish m-3. Random samples were taken from each net cage, at the onset of the experiment and at 60 rearing days, to assess production parameters, specific growth rate and uniformity. We verified a positive linear relationship (p 0.05 for growth parameters, uniformity and final weight. It can be concluded that the density of 300 fish m-3 is the most suitable, because it provides higher net revenue, survival, and a good feed conversion.

  12. Modelling the nitrogen loadings from large yellow croaker (Larimichthys crocea) cage aquaculture.

    Science.gov (United States)

    Cai, Huiwen; Ross, Lindsay G; Telfer, Trevor C; Wu, Changwen; Zhu, Aiyi; Zhao, Sheng; Xu, Meiying

    2016-04-01

    Large yellow croaker (LYC) cage farming is a rapidly developing industry in the coastal areas of the East China Sea. However, little is known about the environmental nutrient loadings resulting from the current aquaculture practices for this species. In this study, a nitrogenous waste model was developed for LYC based on thermal growth and bioenergetic theories. The growth model produced a good fit with the measured data of the growth trajectory of the fish. The total, dissolved and particulate nitrogen outputs were estimated to be 133, 51 and 82 kg N tonne(-1) of fish production, respectively, with daily dissolved and particulate nitrogen outputs varying from 69 to 104 and 106 to 181 mg N fish(-1), respectively, during the 2012 operational cycle. Greater than 80 % of the nitrogen input from feed was predicted to be lost to the environment, resulting in low nitrogen retention (85 %) of the dissolved nitrogen generated from cage farming. This nitrogen loading assessment model is the first to address nitrogenous output from LYC farming and could be a valuable tool to examine the effects of management and feeding practices on waste from cage farming. The application of this model could help improve the scientific understanding of offshore fish farming systems. Furthermore, the model predicts that a 63 % reduction in nitrogenous waste production could be achieved by switching from the use of trash fish for feed to the use of pelleted feed. PMID:26728289

  13. Performance of Tambaqui (Colossoma macropomum in Cages, under Different Percentage of Feeding

    Directory of Open Access Journals (Sweden)

    A. A. B. Pereira

    2014-03-01

    Full Text Available The aim of this study was to evaluate the performance of different rate in percentage feeding of the productivity (Body weight (BW and feed conversion (FC of juvenile tambaqui (Colossoma macropomum, with a total of 13500 animals, distributed in nine cages, with n = 1500 fish/cage, with three replicates in a period of four weeks. The animals were feed with   three treatments: treatment 1 (2% BW; treatment 2 ( 3% BW and treatment 3 (4% BW, divided in two meals,  and feed  with commercial food 36% crude protein. The BW gain was significantly higher for the animals that received feed rate of 4% BW. However, apparent feed conversion was better when used the rate of (2% BW- treatment 1 of tambaqui reared in cages.

  14. Caging the beast: TRIM5α binding to the HIV-1 core.

    Science.gov (United States)

    Diaz-Griffero, Felipe

    2011-05-01

    The potent HIV-1 inhibitor TRIM5α blocks HIV-1 infection by accelerating the uncoating of HIV-1. TRIM5α is known to form higher-order self-association complexes that contribute to the avidity of TRIM5α for the HIV-1 capsid, and are essential to inhibit infection; these higher-order self-association complexes are dependent upon an intact B-box 2 domain. Even though the ability to form higher-order self-association complexes resembles the clathrin triskelion that forms a protein array, or cage, around the endocytic vesicle, evidence for the ability of TRIM5α to assemble a similar type of structure surrounding the HIV-1 core has been lacking. Recent work by Ganser-Pornillos, Chandrasekaran and colleagues has now demonstrated the ability of the restriction factor TRIM5α to "cage" or "net" the HIV-1 core by forming an hexagonal array on the surface of the viral capsid. This hexagonal array is strikingly similar in design to the array formed by the clathrin triskelion on the surface of the clathrin-coated endocytic vesicle. This remarkable finding represents an important advance on our understanding of the restriction factor TRIM5α, and suggests that TRIM5α cages the HIV-1 core in order to terminate infection. The present note discusses the implications of this discovery. PMID:21994740

  15. Lumbar interbody expanding cage. A preliminary study on an animal model.

    Science.gov (United States)

    Manunta, M L; Careddu, G M; Masala, G; Columbano, N; Doria, C; Crissantu, L; Sanna Passino, E

    2008-01-01

    Interbody fusion devices are used in human medicine for treating degenerative diseases of the spine. Currently, there is not a universally accepted assessment tool for determining fusion, and the definitive criteria for diagnosing a successful interbody fusion remain controversial. The aim of this study was to describe microscopic and helical computed tomography (CT) imaging in the assessment of lumbar interbody fusion using cylindrical threaded titanium expanding cage in sheep. One cylindrical threaded expanding titanium cage (Proconcept--SA, Orange, France) was inserted through a transperitoneal approach after radical discectomy and packed with cancellous bone autograft in five adult sheep. The subjects were euthanatized after three, six, 12, 18 and 24 months. CT images revealed lumbar fusion at 12 months post operation, whereas microscopic evaluations indicated the presence of lumbar fusion at 18 months. CT and histological grades were the same in 65% of the cases observed. There were not a significant difference between CT, histological and micro radiographic grades. Helical CT scanning can be considered to be a suitable method for the monitoring of lumbar fusion as it enables observation of the deposition of bony bridging within the cage. PMID:18704248

  16. Structural and electronic properties of uranium-encapsulated Au14 cage

    CERN Document Server

    Gao, Yang; Kang, Seung-gu; Cruz, Camilo Andres Jimenez; Xin, Minsi; Meng, Yan; Han, Jie; Wang, Zhigang; Zhou, Ruhong

    2013-01-01

    The structural properties of the uranium-encapsulated nano-cage U@Au14 are predicted using density functional theory. The presence of the uranium atom makes the Au14 structure more stable than the empty Au14-cage, with a triplet ground electronic state for U@Au14. Analysis of the electronic structure shows that the two frontier single-occupied molecular orbital electrons of U@Au14 mainly originate from the 5f shell of the U atom after charge transfer. Meanwhile, the bonding orbitals have both the 5f and 6d components of the U atom, along with the 5d and 6s components of the Au atoms, indicating the covalent nature of the interaction between the U and Au atoms. Moreover, the charge population analysis shows that this nanostructure displays some unique electronic properties where the encapsulated atom gains electrons while the outer shell loses electrons. Therefore, this designed U@Au14 nano-cage structure is stabilized by ionocovalent interactions. The current findings provide theoretical basis for future synt...

  17. Distance Factors and Croatian Export Obstacles in the EU15: CAGE Approach

    Directory of Open Access Journals (Sweden)

    Helena Miloloža

    2015-07-01

    Full Text Available For long-term sustainability of any enterprise, it is required to observe each market separately and systematically modify business approach to prevailing conditions in each. However, adaptation to each market can be a complex affair that requires certain financial costs but ignoring distinguishing criteria leads to reduction in revenues and undermines long-term profitability. Time saving and cost-effectiveness can be achieved by application of The CAGE Distance Framework – a model that analysis all diversities between two or more countries. Croatia did not yet utilize the benefits that European Union membership provides nor did significantly improved its international business. It is obvious that Croatia faces difficulties in the strategic approach to prospective foreign markets. Therefore, emphasis of this article is on analysis and identification of the distinguishing factors between Croatia and the EU15 in order to facilitate and enhance cooperation among them in the future. Throughout the analysis of Croatian export from the beginning of the economic crisis, this article gives an overview of international collaboration among Croatia and the EU15 and comparative analysis by using The CAGE Distance Framework. This analysis has confirmed significant fluctuations, unexploited potential and problems of the Croatian economy in all dimensions of The CAGE model.

  18. A pecking device as an environmental enrichment for caged laying hens.

    Science.gov (United States)

    Moroki, Yuko; Tanaka, Toshio

    2016-08-01

    To improve the welfare of caged laying hens, a pecking device made of stones was introduced on the cage floor. Twenty-four White Leghorn hens aged 15 months were divided into four groups: single-housed hens with device, single-housed control hens, pair-housed hens with device and pair-housed control hens. Hens housed with the device pecked at various pecking objects less often than control hens. Agonistic behavior was also lower in hens with the device than in hens without the device, implied a possibility of improvement in quality of pecking stimuli with the device. Not only time spent pecking, but also quality of pecking might be important to fill their need for stimulation. Both single- and pair-housed hens more often pecked at the device in the evening. Response to various pecking objects also showed that pecking behaviors were most frequently expressed in the evening. Increased foraging at dusk is a well-known habit; therefore, the increase in pecking behavior in the evening might reflect the hens' general circadian rhythm. These results indicate that the device made of stones could promote some instinctive behavior. Enhancement of behavioral repertories and reduced agonistic behavior with the pecking device might improve the welfare of caged laying hens. PMID:27436770

  19. The Iron Cage and the Gaze: Interpreting Medical Control in the English Health System

    Directory of Open Access Journals (Sweden)

    Mark Exworthy

    2015-05-01

    Full Text Available This paper seeks to determine the value of theoretical ideal-types of medical control. Whilst ideal types (such as the iron cage and gaze need revision in their application to medical settings, they remain useful in describing and explaining patterns of control and autonomy in the medical profession. The apparent transition from the cage to the gaze has often been over-stated since both types are found in many contemporary health reforms. Indeed, forms of neo-bureaucracy have emerged alongside surveillance of the gaze. These types are contextualised and elaborated in terms of two empirical examples: the management of medical performance and financial incentives for senior hospital doctors in England. Findings point towards the reformulation of medical control, an on-going re-stratification of the medical profession, and the internalisation of managerial discourses. The cumulative effect involves the medical profession’s ability to re-cast and enhance its position (vis-à-vis managerial interests.Keywords: medical profession, medical control, iron cage, gaze

  20. Cage correlation and diffusion in strongly coupled three-dimensional Yukawa systems in magnetic fields

    Science.gov (United States)

    Dzhumagulova, K. N.; Masheyeva, R. U.; Ott, T.; Hartmann, P.; Ramazanov, T. S.; Bonitz, M.; Donkó, Z.

    2016-06-01

    The influence of an external homogeneous magnetic field on the quasilocalization of the particles—characterized quantitatively by cage correlation functions—in strongly coupled three-dimensional Yukawa systems is investigated via molecular dynamics computer simulations over a wide domain of the system parameters (coupling and screening strengths, and magnetic field). The caging time is found to be enhanced by the magnetic field B . The anisotropic migration of the particles in the presence of magnetic field is quantified via computing directional correlation functions, which indicate a more significant increase of localization in the direction perpendicular to B , while a moderate increase is also found along the B field lines. Associating the particles' escapes from the cages with jumps of a characteristic length, a connection is found with the diffusion process: the diffusion coefficients derived from the decay time of the directional correlation functions in both the directions perpendicular to and parallel with B are in very good agreement with respective diffusion coefficients values obtained from their usual computation based on the mean-squared displacement of the particles.

  1. Enhancement Effect of Sea Urchin Grow-out Cages in Lucero, Bolinao, Pangasinan

    Directory of Open Access Journals (Sweden)

    Maria Celia Defrance Malay

    2000-12-01

    Full Text Available A preliminary study was conducted on the environmental impact of sea urchin (Tripneustes gratilla Linnaeas grow-out culture in Lucero, Bolinao, Pangasinan. It was hypothesized that the feces generated by the caged urchins (~6,000 individuals at any one time might cause localised sediment organic enrichment and subsequent shifts in benthic faunal communities. Results from preliminary surveys conducted in April and August of 1999 indicated minimal impact of sea urchin grow-out culture on the local reef flat community. Some enhancement of faunal abundance and sediment organic matter content in the cage area were noted; however, the impact was limited to a radius of 5-25 meters from the grow-out cages. The enhancement effects appeared to be seasonal occurrences that were dependent on local currents and degree of wave exposure. Epiphyte biomass, total suspended solids, sediment grain size, and relative water movement seemed largely unaffected by sea urchin grow-out culture. However, more frequent and thorough samplings are needed to validate these initial results. The presence of localised enrichment in sediment organic content and epibenthic faunal density suggest the possibility of converting the sea urchin grow-out area into polyculture systems that would make more efficient use of the food resources available while minimizing potential anthropogenic impacts on the environment.

  2. EnerCage: a smart experimental arena with scalable architecture for behavioral experiments.

    Science.gov (United States)

    Uei-Ming Jow; McMenamin, Peter; Kiani, Mehdi; Manns, Joseph R; Ghovanloo, Maysam

    2014-01-01

    Wireless power, when coupled with miniaturized implantable electronics, has the potential to provide a solution to several challenges facing neuroscientists during basic and preclinical studies with freely behaving animals. The EnerCage system is one such solution as it allows for uninterrupted electrophysiology experiments over extended periods of time and vast experimental arenas, while eliminating the need for bulky battery payloads or tethering. It has a scalable array of overlapping planar spiral coils (PSCs) and three-axis magnetic sensors for focused wireless power transmission to devices on freely moving subjects. In this paper, we present the first fully functional EnerCage system, in which the number of PSC drivers and magnetic sensors was reduced to one-third of the number used in our previous design via multicoil coupling. The power transfer efficiency (PTE) has been improved to 5.6% at a 120 mm coupling distance and a 48.5 mm lateral misalignment (worst case) between the transmitter (Tx) array and receiver (Rx) coils. The new EnerCage system is equipped with an Ethernet backbone, further supporting its modular/scalable architecture, which, in turn, allows experimental arenas with arbitrary shapes and dimensions. A set of experiments on a freely behaving rat were conducted by continuously delivering 20 mW to the electronics in the animal headstage for more than one hour in a powered 3538 cm(2) experimental area. PMID:23955695

  3. Haematological and Biochemical Parameters during the Laying Period in Common Pheasant Hens Housed in Enhanced Cages

    Directory of Open Access Journals (Sweden)

    Petra Hrabčáková

    2014-01-01

    Full Text Available The development of selected haematological and biochemical parameters during the laying period was monitored in common pheasant hens housed in an enhanced cage system. The cages were enhanced by the addition of two perches and a shelter formed by strips of cloth hanging in the corner of the cage. The results showed significant changes in the haematological and biochemical parameters monitored during egg laying. At the time when laying capacity approached a maximum, a decrease was observed (P<0.05 in haematocrit, erythrocytes, and haemoglobin values, whereas monocytes, eosinophils, the heterophil/lymphocyte ratio, phosphorus, and calcium exhibited an increase (P<0.05. At the end of the laying period, an increase (P<0.05 was recorded in the count of leukocytes, heterophils, lymphocytes and basophils, the heterophil to lymphocyte ratio, and the concentrations of aspartate aminotransferase, cholesterol, phosphorus, and calcium, whereas lower values (P<0.05 were recorded for haematocrit and plasma total protein in comparison with the values of the indicators at the beginning of the laying period. The results provide new information about dynamic changes in selected haematological and biochemical parameters in clinically healthy common pheasant hens during the laying period.

  4. Efficacy of PEEK Cages and Plate Augmentation in Three-Level Anterior Cervical Fusion of Elderly Patients

    OpenAIRE

    Song, Kyung Jin; Kim, Gyu Hyung; Choi, Byeong Yeol

    2011-01-01

    Background To evaluate the clinical efficacy of three-level anterior cervical arthrodesis with polyethyletherketone (PEEK) cages and plate fixation for aged and osteoporotic patients with degenerative cervical spinal disorders. Methods Twenty one patients, who had undergone three-level anterior cervical arthrodesis with a cage and plate construct for degenerative cervical spinal disorder from November 2001 to April 2007 and were followed up for at least two years, were enrolled in this study....

  5. Laboratory tests for controlling poultry red mites (Dermanyssus gallinae) with predatory mites in small 'laying hen' cages

    OpenAIRE

    Lesna, Izabela; Sabelis, Maurice W.; van Niekerk, Thea G. C. M.; Komdeur, Jan

    2012-01-01

    To assess their potential to control poultry red mites (Dermanyssus gallinae), we tested selected predaceous mites (Androlaelaps casalis and Stratiolaelaps scimitus) that occur naturally in wild bird nests or sometimes spontaneously invade poultry houses. This was done under laboratory conditions in cages, each with 2–3 laying hens, initially 300 poultry red mites and later the release of 1,000 predators. These small-scale tests were designed to prevent mite escape from the cages and they wer...

  6. Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO

    Directory of Open Access Journals (Sweden)

    Marilena Carbone

    2016-03-01

    In the process of searching a pathway to augment the intracellular uptake of proton caged compounds, we probed the association of 1-(2-nitrophenyl-ethylhexadecyl sulfonate (HDNS with DMSO, an agent to enhance the membrane permeability. We found out a different UV-induced protonation mechanism that opens up to new conduits of employing of proton caged compounds. Here, we report the infrared data we collected in this set of experiments.

  7. Intracage Ammonia Levels in Static and Individually Ventilated Cages Housing C57BL/6 Mice on 4 Bedding Substrates

    OpenAIRE

    Ferrecchia, Christie E.; Jensen, Kelly; Van Andel, Roger

    2014-01-01

    The relationship among ammonia levels, cage-changing frequency, and bedding types is an important and potentially controversial topic in the laboratory animal science community. Some bedding options may not provide sufficient urine absorption and bacterial regulation to minimize ammonia production during the interval between cage changes. High intracage ammonia levels can cause subclinical degeneration and inflammation of nasal passages, rhinitis and olfactory epithelial necrosis in exposed m...

  8. Voltage control in the stator circuit of cage induction machine operating as generator in small scale hydropower plant

    OpenAIRE

    Kandyba, Andrzej; Kalus, Marian; Kurytnik, Igor Piotr

    2012-01-01

    The synthesis of RMS voltage control system in the stator circuit of squirrel cage induction machine based on the linear criterion of " optimum magnitude" by C. Kessler 'a was performed. The squirrel cage induction machine was operating as a generator in autonomous (isolated) network. Induction machine is driven by an induction machine supplied from the inverter, which simulates the low pressure head water turbine. Synthesis process of the control system was supported by experimental studi...

  9. Optical and magnetic excitations of metal-encapsulating Si cages: A systematic study by time-dependent density functional theory

    OpenAIRE

    Oliveira, Micael J. T.; Medeiros, Paulo V. C.; Sousa, José R. F.; Nogueira, Fernando; Gueorguiev, Gueorgui K.

    2013-01-01

    Systematic study of the optical and magnetic excitations of twelve MSi$_{12}$ and four MSi$_{10}$ transition metal encapsulating Si cages has been carried out by employing real time time-dependent density functional theory. Criteria for the choice of transition metals (M) are clusters' stability, synthesizability, and diversity. It was found that both the optical absorption and the spin-susceptibility spectra are mainly determined by, in decreasing order of importance: 1) the cage shape, 2) t...

  10. Report of the baseline survey undertaken on the Chinese cage site in Napoleon Gulf, Northern Lake Victoria, 12 March 2012

    OpenAIRE

    Magezi, G.; Naluwairo, J.; Ocaya, H.; Kiggundu, V.; Pabire Ghandi, W.; Wandera, S.B.; Olokotum, M.; Ndawula, L.M.

    2012-01-01

    The government of the People's Republic of China through a 2007 agreement with the Government of the Republic of Uganda, has establishment of an Agricultural Technology Demonstration Center (ATDC). The first phase covering the building of aquaculture infrastructure at Kajjansi ARDC is complete and the second operation phase has started in which facilities for cage culture have been set up in the Napoleon gulf, northern Lake Victoria near Jinja. The cage facility is aimed at boosting fish far...

  11. Interactions Between Housing Density and Ambient Temperature in the Cage Environment: Effects on Mouse Physiology and Behavior

    OpenAIRE

    Toth, Linda A; Trammell, Rita A; Ilsley-Woods, Megan

    2015-01-01

    To determine how housing density and ambient temperature interact to influence the physiology and behavior of mice, we systematically varied housing density (1 to 5 mice per cage) and ambient temperature (22, 26, or 30 °C) and measured effects on body weight, food intake, diurnal patterns of locomotor activity and core temperature, fecal corticosterone, and serum cytokine and adipokine panels. Temperatures inside cages housing 5 mice were 1 to 2 °C higher than the ambient temperature. As the ...

  12. Module 13: Bulk Packaging Shipments by Highway

    International Nuclear Information System (INIS)

    The Hazardous Materials Modular Training Program provides participating United States Department of Energy (DOE) sites with a basic, yet comprehensive, hazardous materials transportation training program for use onsite. This program may be used to assist individual program entities to satisfy the general awareness, safety training, and function specific training requirements addressed in Code of Federal Regulation (CFR), Title 49, Part 172, Subpart H -- ''Training.'' Module 13 -- Bulk Packaging Shipments by Highway is a supplement to the Basic Hazardous Materials Workshop. Module 13 -- Bulk Packaging Shipments by Highway focuses on bulk shipments of hazardous materials by highway mode, which have additional or unique requirements beyond those addressed in the ten module core program. Attendance in this course of instruction should be limited to those individuals with work experience in transporting hazardous materials utilizing bulk packagings and who have completed the Basic Hazardous Materials Workshop or an equivalent. Participants will become familiar with the rules and regulations governing the transportation by highway of hazardous materials in bulk packagings and will demonstrate the application of these requirements through work projects and examination

  13. Development of superconductor bulk for superconductor bearing

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Joong; Jun, Byung Hyuk; Park, Soon Dong (and others)

    2008-08-15

    Current carrying capacity is one of the most important issues in the consideration of superconductor bulk materials for engineering applications. There are numerous applications of Y-Ba-Cu-O (YBCO) bulk superconductors e.g. magnetic levitation train, flywheel energy storage system, levitation transportation, lunar telescope, centrifugal device, magnetic shielding materials, bulk magnets etc. Accordingly, to obtain YBCO materials in the form of large, single crystals without weak-link problem is necessary. A top seeded melt growth (TSMG) process was used to fabricate single crystal YBCO bulk superconductors. The seeded and infiltration growth (IG) technique was also very promising method for the synthesis of large, single-grain YBCO bulk superconductors with good superconducting properties. 5 wt.% Ag doped Y211 green compacts were sintered at 900 .deg. C {approx} 1200 .deg.C and then a single crystal YBCO was fabricated by an infiltration method. A refinement and uniform distribution of the Y211 particles in the Y123 matrix were achieved by sintering the Ag-doped samples. This enhancement of the critical current density was ascribable to a fine dispersion of the Y211 particles, a low porosity and the presence of Ag particles. In addition, we have designed and manufactured large YBCO single domain with levitation force of 10-13 kg/cm{sup 2} using TSMG processing technique.

  14. Assessment of the effects of cage fish-farming on damselfish-associated food chains using stable-isotope analyses

    International Nuclear Information System (INIS)

    Highlights: • Damselfishes living at sites near a cage farm bore lower δ13C and higher δ15N. • Similar trends occurred in zooplankton and detritus, major foods for damselfishes. • δ15N enrichment in fish may have arisen from the uptake of excess feed and prey. • Farm wastes were documented entering the ecosystem through the pelagic food chain. • No clear evidence of the effects of cage farming on stable isotopes in macroalgae. - Abstract: To assess the effect of cage fish-farming on the coral reef ecosystem off Xiaoliuchiu Island, southern Taiwan, geographical differences in the food chain of each of two damselfishes, Pomacentrus vaiuli and Chromis margaritifer, were examined using a stable-isotope approach. For each damselfish, individuals were found to consume similar foods at all sites. However, specimens collected at sites near the cage farm (as the experimental sites) exhibited lower δ13C and higher δ15N signatures compared to those from reference sites. Similar trends also occurred in the zooplankton and detritus, two major food sources for both damselfishes. This finding indicates that particulate organic matter released by the farm may have entered the coral reef ecosystem through the pelagic food chain. Artificial reef emplacement is recommended to provide extra habitats under cage farms to support additional pelagic-feeding fish populations, thereby reducing environmental impacts of cage farming on coral reefs

  15. A diphoton resonance from bulk RS

    Science.gov (United States)

    Csáki, Csaba; Randall, Lisa

    2016-07-01

    Recent LHC data hinted at a 750 GeV mass resonance that decays into two photons. A significant feature of this resonance is that its decays to any other Standard Model particles would be too low to be detected so far. Such a state has a compelling explanation in terms of a scalar or a pseudoscalar that is strongly coupled to vector states charged under the Standard Model gauge groups. Such a scenario is readily accommodated in bulk RS with a scalar localized in the bulk away from but close to the Higgs. Turning this around, we argue that a good way to find the elusive bulk RS model might be the search for a resonance with prominent couplings to gauge bosons.

  16. Micro benchtop optics by bulk silicon micromachining

    Science.gov (United States)

    Lee, Abraham P.; Pocha, Michael D.; McConaghy, Charles F.; Deri, Robert J.

    2000-01-01

    Micromachining of bulk silicon utilizing the parallel etching characteristics of bulk silicon and integrating the parallel etch planes of silicon with silicon wafer bonding and impurity doping, enables the fabrication of on-chip optics with in situ aligned etched grooves for optical fibers, micro-lenses, photodiodes, and laser diodes. Other optical components that can be microfabricated and integrated include semi-transparent beam splitters, micro-optical scanners, pinholes, optical gratings, micro-optical filters, etc. Micromachining of bulk silicon utilizing the parallel etching characteristics thereof can be utilized to develop miniaturization of bio-instrumentation such as wavelength monitoring by fluorescence spectrometers, and other miniaturized optical systems such as Fabry-Perot interferometry for filtering of wavelengths, tunable cavity lasers, micro-holography modules, and wavelength splitters for optical communication systems.

  17. Bulk amorphous Mg-based alloys

    DEFF Research Database (Denmark)

    Pryds, Nini

    The present paper describes the preparation and properties of bulk amorphous quarternary Mg-based alloys and the influence of additional elements on the ability of the alloy to form bulk amorphous. The main goal is to find a Mg-based alloy system which shows both high strength to weight ratio and a...... low glass transition temperature. The alloys were prepared by using a relatively simple technique, i.e. rapid cooling of the melt in a copper wedge mould. The essential structural changes that are achieved by going from the amorphous to the crystalline state through the supercooled liquid state are...... discussed in this paper. On the basis of these measurements phase diagrams of the different systems were constructed. Finally, it is demonstrated that when pressing the bulk amorphous alloy onto a metallic dies at temperatures within the supercooled liquid region, the alloy faithfully replicates the surface...

  18. Orchestrating Bulk Data Movement in Grid Environments

    Energy Technology Data Exchange (ETDEWEB)

    Vazhkudai, SS

    2005-01-25

    Data Grids provide a convenient environment for researchers to manage and access massively distributed bulk data by addressing several system and transfer challenges inherent to these environments. This work addresses issues involved in the efficient selection and access of replicated data in Grid environments in the context of the Globus Toolkit{trademark}, building middleware that (1) selects datasets in highly replicated environments, enabling efficient scheduling of data transfer requests; (2) predicts transfer times of bulk wide-area data transfers using extensive statistical analysis; and (3) co-allocates bulk data transfer requests, enabling parallel downloads from mirrored sites. These efforts have demonstrated a decentralized data scheduling architecture, a set of forecasting tools that predict bandwidth availability within 15% error and co-allocation architecture, and heuristics that expedites data downloads by up to 2 times.

  19. Bulk Comptonization by Turbulence in Accretion Disks

    CERN Document Server

    Kaufman, J

    2016-01-01

    Radiation pressure dominated accretion discs around compact objects may have turbulent velocities that greatly exceed the electron thermal velocities within the disc. Bulk Comptonization by the turbulence may therefore dominate over thermal Comptonization in determining the emergent spectrum. Bulk Comptonization by divergenceless turbulence is due to radiation viscous dissipation only. It can be treated as thermal Comptonization by solving the Kompaneets equation with an equivalent "wave" temperature, which is a weighted sum over the power present at each scale in the turbulent cascade. Bulk Comptonization by turbulence with non-zero divergence is due to both pressure work and radiation viscous dissipation. Pressure work has negligible effect on photon spectra in the limit of optically thin turbulence, and in this limit radiation viscous dissipation alone can be treated as thermal Comptonization with a temperature equivalent to the full turbulent power. In the limit of extremely optically thick turbulence, ra...

  20. Synthesis of Bulk Superconducting Magnesium Diboride

    Directory of Open Access Journals (Sweden)

    Margie Olbinado

    2002-06-01

    Full Text Available Bulk polycrystalline superconducting magnesium diboride, MgB2, samples were successfully prepared via a one-step sintering program at 750°C, in pre Argon with a pressure of 1atm. Both electrical resistivity and magnetic susceptibility measurements confirmed the superconductivity of the material at 39K, with a transition width of 5K. The polycrystalline nature, granular morphology, and composition of the sintered bulk material were confirmed using X-ray diffractometry (XRD, scanning electron microscopy (SEM, and energy dispersive X-ray analysis (EDX.