WorldWideScience

Sample records for cadsr content development

  1. Overexpression of CaDSR6 increases tolerance to drought and salt stresses in transgenic Arabidopsis plants.

    Science.gov (United States)

    Kim, Eun Yu; Seo, Young Sam; Park, Ki Youl; Kim, Soo Jin; Kim, Woo Taek

    2014-11-15

    The partial CaDSR6 (Capsicum annuum Drought Stress Responsive 6) cDNA was previously identified as a drought-induced gene in hot pepper root tissues. However, the cellular role of CaDSR6 with regard to drought stress tolerance was unknown. In this report, full-length CaDSR6 cDNA was isolated. The deduced CaDSR6 protein was composed of 234 amino acids and contained an approximately 30 amino acid-long Asp-rich domain in its central region. This Asp-rich domain was highly conserved in all plant DSR6 homologs identified and shared a sequence identity with the N-terminal regions of yeast p23(fyp) and human hTCTP, which contain Rab protein binding sites. Transgenic Arabidopsis plants overexpressing CaDSR6 (35S:CaDSR6-sGFP) were tolerant to high salinity, as identified by more vigorous root growth and higher levels of total chlorophyll than wild type plants. CaDSR6-overexpressors were also more tolerant to drought stress compared to wild type plants. The 35S:CaDSR6-sGFP leaves retained their water content and chlorophyll more efficiently than wild type leaves in response to dehydration stress. The expression of drought-induced marker genes, such as RD20, RD22, RD26, RD29A, RD29B, RAB18, KIN2, ABF3, and ABI5, was markedly increased in CaDSR6-overexpressing plants relative to wild type plants under both normal and drought conditions. These results suggest that overexpression of CaDSR6 is associated with increased levels of stress-induced genes, which, in turn, conferred a drought tolerant phenotype in transgenic Arabidopsis plants. Overall, our data suggest that CaDSR6 plays a positive role in the response to drought and salt stresses. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Development of life skills through physics content

    Science.gov (United States)

    Pivarči, Tomáš; Raganová, Janka

    2017-01-01

    The paper deals with students' life skills which the physics teacher should intentionally develop through physics content. An attention is given not only to the physics content and activities connected with it, but also to the development of responsibility, freedom, ability to make decisions, group cooperation, self-evaluation and experience of success. Three activities implemented in the seventh class of the elementary school are described in the paper. Authors describe reasons for class selection, the physics content and the used methods as well as the skills which they decided to purposely develop. They emphasize the importance of activities requiring students' inquiry-based learning and the need to change organization and philosophy of physics teaching at secondary schools. At the end of the paper authors analyze the achievement of objectives, positives as well as negatives of the implemented approaches and propose changes for a future realization.

  3. From Storyboard to Story: Animation Content Development

    Science.gov (United States)

    Mou, Tsai-Yun; Jeng, Tay-Sheng; Chen, Chien-Hsu

    2013-01-01

    This research focused on a new method in the development of animation story content, which could shorten the creation process and arouse new ideas. Two phases of experiments were conducted to explore this reversed model. The first phase is a pretest of participants' creativity, which was a base for further examination the relationship between…

  4. Contents of Education for Sustainable Development

    Directory of Open Access Journals (Sweden)

    D S Ermakov

    2013-12-01

    Full Text Available The essence of education for sustainable development (ESD has been disclosed in this article. The definition of ESD has been formulated. The key approaches to the formation of the ESD curriculum have been designated. The criteria for selecting the content of ESD have been proposed. The feasibility of applying the competency based approach has been shown.

  5. Teacher Professional Development through Digital Content Evaluation

    Science.gov (United States)

    Xie, Kui; Kim, Min Kyu; Cheng, Sheng-Lun; Luthy, Nicole C.

    2017-01-01

    In this study, researchers designed and implemented a 1-year professional development (PD) program that focused on supporting teachers in evaluating and selecting digital learning contents. Participants in this investigation included 109 teachers who consented to the study amongst a total of 171 teachers from five school districts across central…

  6. The Challenges in Developing E-Content

    Directory of Open Access Journals (Sweden)

    Jowati Juhary

    2010-11-01

    Full Text Available Malaysia is considered an active key player in information communication technologies (ICTs especially in education. In fact, in the National Higher Education Strategic Plan, one of the Critical Agenda Projects (CAPs of the Minister of Higher Education is e-learning. It goes without saying that all higher learning providers in Malaysia must be prepared to provide state-of-the-art facilities for the students. One critical aspect of e-learning is the quality and quantity of the content, or what will be referred by many scholars as e-content. This paper attempts to identify the challenges of content development for e-learning practice at the National Defence University of Malaysia (NDUM. It is crucial to investigate this issue since the university just purchased its Learning Management System (LMS. It is expected that resistance will be present as the academics at the defence university is a mixture of junior and senior lecturers, as well as civilian and military lecturers; and some of these academics have been teaching without the assistance of e-learning. In so doing, the methodology of this paper will mainly be content analysis of various reports, governmental documents, as well as semi-structured interviews with lecturers at the NDUM. As this paper acts as a preliminary investigation into the issue of e-content at the university, only seven lecturers were interviewed. Initial findings suggest that there are basically five challenges of developing e-content at the NDUM. These include the lack of ICT and e-learning policy that can provide guidelines to academics; the uncertainty of ownership for e-learning initiatives; the lack of understanding of the roles of e-learning; the lack of awareness on e-learning; and the difficulties to develop military based content due to confidentiality issues. Two possible solutions for these challenges are also examined which take into consideration the urgent need to set up an e-Learning Unit and to provide

  7. LSDS Development for Isotopic Fissile Content Assay

    International Nuclear Information System (INIS)

    Lee, Yong Deok; Park, Chang Je; Park, Geun Il; Lee, Jung Won; Song, Kee Chan

    2010-01-01

    Concerning the sustainable energy supply and green house effect, nuclear energy became the most feasible option to meet the energy demand in Korea. However, the production of the spent nuclear fuel is the inevitable situation. Since the first nuclear power plant started to produce the electricity in Korea, the accumulated amount of spent fuels exceeded 10k tomes recently. The accumulation of the spent fuels is the big issue in the society. Therefore, as an option which strengthens the nuclear proliferation resistance and reduces the amount of spent fuels, sodium fast reactor (SFR) program linked with pyro-processing is under development to re-use the PWR spent fuel and produce the energy. In the process, the produced metallic material involves uranium and TRU (transuranic; neptunium, plutonium, and americium). The uranium-TRU is used to fabricate SFR fuel. The burning the recycled fuel in the reactor is to solve the current spent fuel storage problem and to minimize the actinides accumulation having long half-life. Generally, the spent fuel from PWR has unburned ∼1 % U235, produced ∼0.5 % plutonium from decay chain, ∼3 % fission products, ∼ 0.1 % minor actinides (MA) and uranium remainder. About 1.5 % fissile materials still exist in the spent fuel. Therefore, spent fuel is not only waste but energy resource. The direct and isotopic fissile content assay is the crucial technology for the spent fuel reuse. Additionally, the fissile content analysis will contribute to the optimum storage design and safe spent fuel management. Several nondestructive technologies have been developed for the spent fuel assay; gamma ray measurement, passive and active neutron measurements. Spent fuel emits intense gamma rays and neutrons by (a, n) and spontaneous fission. This intense background has the limitation on the direct analysis of fissile materials. Recently, to analyze the individual fissile content, leadslowing down spectrometer (LSDS) has been being developed in Korea

  8. Content

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    secondary levels. In subject matter didactics, the question of content is more developed, but it is still mostly confined to teaching on lower levels. As for higher education didactics, discussions on selection of content are almost non-existent on the programmatic level. Nevertheless, teachers are forced...... curriculum, in higher education, and to generate analytical categories and criteria for selection of content, which can be used for systematic didactical reflection. The larger project also concerns reflection on and clarification of the concept of content, including the relation between content at the level......Aim, content and methods are fundamental categories of both theoretical and practical general didactics. A quick glance in recent pedagogical literature on higher education, however, reveals a strong preoccupation with methods, i.e. how teaching should be organized socially (Biggs & Tang, 2007...

  9. Helping Students Develop an Appreciation for School Content

    Science.gov (United States)

    Pugh, Kevin J.; Phillips, Michael M.

    2011-01-01

    The topic of content appreciation (i.e., developing a broad valuing of curricular content) has not received the attention it deserves. In this article, the authors present Brophy's (2008a; 2008b) model of content appreciation in the context of a hypothetical case study of a teacher trying to foster content appreciation. In doing so, they…

  10. Development of Efficient Authoring Software for e-Learning Contents

    Science.gov (United States)

    Kozono, Kazutake; Teramoto, Akemi; Akiyama, Hidenori

    The contents creation in e-Learning system becomes an important problem. The contents of e-Learning should include figure and voice media for a high-level educational effect. However, the use of figure and voice complicates the operation of authoring software considerably. A new authoring software, which can build e-Learning contents efficiently, has been developed to solve this problem. This paper reports development results of the authoring software.

  11. The Complexities of Developing Accessible Web Content for Mobile Devices

    Science.gov (United States)

    Hancock, Richard

    This paper is concerned with the development of accessible mobile content and the complexities that arise during this process. The paper gives an overview of the popularity and advantages of mobile devices before tackling the issues surrounding content development, particularly within an educational context. The paper concludes with an overview of an application that was developed for higher education students within a UK college that had a mobile counterpart, allowing the artefact to transcend the typical desktop environment.

  12. CLIL Teacher Professional Development for Content Teachers in Thailand

    Directory of Open Access Journals (Sweden)

    Punwalai Kewara

    2018-01-01

    Full Text Available In Thailand, the new educational policy is mandated to encourage content teachers to integrate English in content classrooms. The policy has created tensions and misconceptions among content teachers, who must change the medium of instruction from Thai to English. This paper presents an attempt to foster teacher knowledge about the Content and Language Integrated Learning (CLIL approach in a teacher professional development program. Classroom language in English and CLIL classroom structure were provided for 15 teachers at a secondary school. Four volunteer teachers were observed to determine the extent to which teachers implemented CLIL. The findings revealed the teachers partly implemented classroom language in English and the provided CLIL structure was not evident. The contribution of this paper is to the literature of CLIL teacher professional development effectiveness and the implementation fidelity of a professional development program.

  13. New opportunities for developing tomato varieties with enhanced carotenoid content

    Directory of Open Access Journals (Sweden)

    Miguel Leiva-Brondo

    Full Text Available ABSTRACT The development of varieties with a high content of antioxidant compounds, such as carotenoids, has become a major focus in the marketing of tomato. Several mutants have been used in the development of high pigment varieties, but the significant influence of the environment on carotenoid content and the presence of negative side effects in vegetative growth and yield have limited the success of these variants. Consequently, the identification of alternative sources of variation in the quest for high carotenoid content is ongoing. In this study, 12 accessions of Solanum lycopersicum (including the former var cerasiforme and S. pimpinelifolium have been evaluated in three different environments: open field and glasshouse cultivation at two sites. Three accessions (BGV6195 of S. pimpinellifolium, LA1423 of the former var cerasiforme and LA3633 a possible hybrid between S. pimpinellifolium and S. lycopersicum showed outstanding and stable lycopene content, that doubled in all three environments the content of the positive control LA3538, with the high pigment-1 mutation (hp1. In addition, accession CATIE14812 would also be interesting as regards improvement of β-carotene content. These materials offer new opportunities in the development of tomato varieties with enriched and reliable carotenoid content and the close taxonomic relationship of these accessions with cultivated tomato will facilitate their use in breeding programs.

  14. Inquiring into Pre-Service Content Area Teachers' Development of Literacy Practices and Pedagogical Content Knowledge

    Science.gov (United States)

    Mitton Kukner, Jennifer; Murray Orr, Anne

    2015-01-01

    The focus of this qualitative multi-year case study is on preservice teachers' experiences related to the development of their literacy practices in teaching high school science, math, social studies and other content area courses during their final field placement in a teacher education program. Results indicate tangible indicators of overall…

  15. Comfort and Content: Considerations for Informal Science Professional Development

    Science.gov (United States)

    Holliday, Gary M.; Lederman, Norman G.; Lederman, Judith S.

    2014-01-01

    This study looked at a life science course that was offered at and taught by education staff of a large informal science institution (ISI) located in the Midwest. The curriculum, materials, and agendas for the course were developed by education staff and complemented a permanent life science exhibition. The researcher developed a content test…

  16. Developing Holocaust Curricula: The Content Decision-Making Process

    Science.gov (United States)

    Lindquist, David H.

    2008-01-01

    The content decision-making process involved in developing Holocaust curricula is unusually complex and problematic. Educators must consider factors such as historical accuracy, selection of topics covered, potential teaching materials (such as textbooks and literary texts), and graphic materials (such as films and photographs) as they plan their…

  17. Incorporating Sustainability Content and Pedagogy through Faculty Development

    Science.gov (United States)

    Hurney, Carol A.; Nash, Carole; Hartman, Christie-Joy B.; Brantmeier, Edward J.

    2016-01-01

    Purpose: Key elements of a curriculum are presented for a faculty development program that integrated sustainability content with effective course design methodology across a variety of disciplines. The study aims to present self-reported impacts for a small number of faculty participants and their courses. Design/methodology/approach: A yearlong…

  18. Developing Content for an M.B.A. Communications Class.

    Science.gov (United States)

    Shelby, Annette N.

    1983-01-01

    Outlines an M.B.A. communications course which includes source materials and content development frameworks for four different topic areas: (1) company, industry, and organization data; (2) management theory and organizational design; (3) crisis communication; and (4) issues management. (RAE)

  19. Contents

    Directory of Open Access Journals (Sweden)

    Editor IJRED

    2012-11-01

    Full Text Available International Journal of Renewable Energy Development www.ijred.com Volume 1             Number 3            October 2012                ISSN 2252- 4940   CONTENTS OF ARTICLES page Design and Economic Analysis of a Photovoltaic System: A Case Study 65-73 C.O.C. Oko , E.O. Diemuodeke, N.F. Omunakwe, and E. Nnamdi     Development of Formaldehyde Adsorption using Modified Activated Carbon – A Review 75-80 W.D.P Rengga , M. Sudibandriyo and M. Nasikin     Process Optimization for Ethyl Ester Production in Fixed Bed Reactor Using Calcium Oxide Impregnated Palm Shell Activated Carbon (CaO/PSAC 81-86 A. Buasri , B. Ksapabutr, M. Panapoy and N. Chaiyut     Wind Resource Assessment in Abadan Airport in Iran 87-97 Mojtaba Nedaei       The Energy Processing by Power Electronics and its Impact on Power Quality 99-105 J. E. Rocha and B. W. D. C. Sanchez       First Aspect of Conventional Power System Assessment for High Wind Power Plants Penetration 107-113 A. Merzic , M. Music, and M. Rascic   Experimental Study on the Production of Karanja Oil Methyl Ester and Its Effect on Diesel Engine 115-122 N. Shrivastava,  , S.N. Varma and M. Pandey  

  20. Development and validation of the goal content for exercise questionnaire.

    Science.gov (United States)

    Sebire, Simon J; Standage, Martyn; Vansteenkiste, Maarten

    2008-08-01

    Self-determination theory (SDT; Deci & Ryan, 2000) proposes that intrinsic, relative to extrinsic, goal content is a critical predictor of the quality of an individual's behavior and psychological well-being. Through three studies, we developed and psychometrically tested a measure of intrinsic and extrinsic goal content in the exercise context: the Goal Content for Exercise Questionnaire (GCEQ). In adults, exploratory (N = 354; Study 1) and confirmatory factor analyses (N = 312; Study 2) supported a 20-item solution consisting of 5 lower order factors (i.e., social affiliation, health management, skill development, image and social recognition) that could be subsumed within a 2-factor higher order structure (i.e., intrinsic and extrinsic). Evidence for external validity, temporal stability, gender invariance, and internal consistency of the GCEQ was found. An independent sample (N = 475; Study 3) provided further support for the lower order structure of the GCEQ and some support for the higher order structure. The GCEQ was supported as a measure of exercise-based goal content, which may help understand how intrinsic and extrinsic goals can motivate exercise behavior.

  1. Development of Extended Content Standards for Biodiversity Data

    Science.gov (United States)

    Hugo, Wim; Schmidt, Jochen; Saarenmaa, Hannu

    2013-04-01

    Interoperability in the field of Biodiversity observation has been strongly driven by the development of a number of global initiatives (GEO, GBIF, OGC, TDWG, GenBank, …) and its supporting standards (OGC-WxS, OGC-SOS, Darwin Core (DwC), NetCDF, …). To a large extent, these initiatives have focused on discoverability and standardization of syntactic and schematic interoperability. Semantic interoperability is more complex, requiring development of domain-dependent conceptual data models, and extension of these models with appropriate ontologies (typically manifested as controlled vocabularies). Biodiversity content has been standardized partly, for example through Darwin Core for occurrence data and associated taxonomy, and through Genbank for genetic data, but other contexts of biodiversity observation have lagged behind - making it difficult to achieve semantic interoperability between distributed data sources. With this in mind, WG8 of GEO BON (charged with data and systems interoperability) has started a work programme to address a number of concerns, one of which is the gap in content standards required to make Biodiversity data truly interoperable. The paper reports on the framework developed by WG8 for the classification of Biodiversity observation data into 'families' of use cases and its supporting data schema, where gaps, if any, in the availability if content standards have been identified, and how these are to be addressed by way of an abstract data model and the development of associated content standards. It is proposed that a minimum set of standards (1) will be required to address the scope of Biodiversity content, aligned with levels and dimensions of observation, and based on the 'Essential Biodiversity Variables' (2) being developed by GEO BON . The content standards are envisaged as loosely separated from the syntactic and schematic standards used for the base data exchange: typically, services would offer an existing data standard (DwC, WFS

  2. Development and content validation of the power mobility training tool.

    Science.gov (United States)

    Kenyon, Lisa K; Farris, John P; Cain, Brett; King, Emily; VandenBerg, Ashley

    2018-01-01

    This paper outlines the development and content validation of the power mobility training tool (PMTT), an observational tool designed to assist therapists in developing power mobility training programs for children who have multiple, severe impairments. Initial items on the PMTT were developed based on a literature review and in consultation with therapists experienced in the use of power mobility. Items were trialled in clinical settings, reviewed, and refined. Items were then operationalized and an administration manual detailing scoring for each item was created. Qualitative and quantitative methods were used to establish content validity via a 15 member, international expert panel. The content validity ratio (CVR) was determined for each possible item. Of the 19 original items, 10 achieved minimum required CVR values and were included in the final version of the PMTT. Items related to manoeuvring a power mobility device were merged and an item related to the number of switches used concurrently to operate a power mobility device were added to the PMTT. The PMTT may assist therapists in developing training programs that facilitate the acquisition of beginning power mobility skills in children who have multiple, severe impairments. Implications for Rehabilitation The Power Mobility Training Tool (PMTT) was developed to help guide the development of power mobility intervention programs for children who have multiple, severe impairments. The PMTT can be used with children who access a power mobility device using either a joystick or a switch. Therapists who have limited experience with power mobility may find the PMTT to be helpful in setting up and conducting power mobility training interventions as a feasible aspect of a plan of care for children who have multiple, severe impairments.

  3. Development for equipment of the milk macromolecules content detection

    Science.gov (United States)

    Ding, Guochao; Li, Weimin; Shang, Tingyi; Xi, Yang; Gao, Yunli; Zhou, Zhen

    Developed an experimental device for rapid and accurate detection of milk macromolecular content. This device developed based on laser scattered through principle, the principle use of the ingredients of the scattered light and transmitted light ratio characterization of macromolecules. Peristaltic pump to achieve automatic input and output of the milk samples, designing weak signal detection amplifier circuit for detecting the ratio with ICL7650. Real-time operating system μC / OS-II is the core design of the software part of the whole system. The experimental data prove that the device can achieve a fast real-time measurement of milk macromolecules.

  4. Developing Pedagogical Content Knowledge: Lessons Learned from Intervention Studies

    Directory of Open Access Journals (Sweden)

    Marie Evens

    2015-01-01

    Full Text Available Pedagogical content knowledge (PCK is generally accepted as positively impacting teaching quality and student learning. Therefore, research on PCK development in (prospective teachers is highly relevant. Based on a search in three databases (ERIC, PsycInfo, and Web of Science, a systematic review is conducted on intervention studies aiming at PCK development. The research questions are threefold: (1 How are the studies designed? (2 How are the interventions designed? and (3 What elements of interventions contribute to PCK development? The results show that most intervention studies are conducted in math and science education and use a qualitative methodology. Reflection, PCK courses, contact with other teachers, and experiences in educational practice are typically part of effective interventions. The review enables the identification of clear guidelines that may strengthen future research on stimulating PCK.

  5. Contents Development of Library Signage Manual in Korea

    Directory of Open Access Journals (Sweden)

    In-Ja Ahn

    2011-12-01

    Full Text Available There is an increase in the need of an unified manual for library signage system, due to recent increase in library construction or remodeling. This paper, therefore, can be a basic research to develop library signage system manual. Based on an anual released from KLA and the sum of opinions of expert groups, this research proposes a concrete list of contents for library signage system manual as follows. First, there is a need of theoretical basis of library signage system. Second, for the actual practices of signage system, planning, check list, and standard terms shall be necessary.

  6. Contents Development of Library Signage Manual in Korea

    OpenAIRE

    In-Ja Ahn

    2011-01-01

    There is an increase in the need of an unified manual for library signage system, due to recent increase in library construction or remodeling. This paper, therefore, can be a basic research to develop library signage system manual. Based on an anual released from KLA and the sum of opinions of expert groups, this research proposes a concrete list of contents for library signage system manual as follows. First, there is a need of theoretical basis of library signage system. Second, for the ac...

  7. CLIL Teacher Professional Development for Content Teachers in Thailand

    Science.gov (United States)

    Kewara, Punwalai; Prabjandee, Denchai

    2018-01-01

    In Thailand, the new educational policy is mandated to encourage content teachers to integrate English in content classrooms. The policy has created tensions and misconceptions among content teachers, who must change the medium of instruction from Thai to English. This paper presents an attempt to foster teacher knowledge about the Content and…

  8. Developing a Scale to Measure Content Knowledge and Pedagogy Content Knowledge of In-Service Elementary Teachers on Fractions

    Science.gov (United States)

    Kazemi, Farhad; Rafiepour, Abolfazl

    2018-01-01

    The main purpose of this study was to develop a scale for measuring content knowledge (CK) and pedagogy content knowledge (PCK) of in-service elementary teachers on mathematical fractions. Another aim of this study was to consider whether CK and PCK are separate from each other, or are in a single body. Therefore, a scale containing 22 items about…

  9. Evaluation of the Professional Development Program on Web Based Content Development

    Science.gov (United States)

    Yurdakul, Bünyamin; Uslu, Öner; Çakar, Esra; Yildiz, Derya G.

    2014-01-01

    The aim of this study is to evaluate the professional development program on web based content development (WBCD) designed by the Ministry of National Education (MoNE). Based on the theoretical CIPP model by Stufflebeam and Guskey's levels of evaluation, the study was carried out as a case study. The study group consisted of the courses that…

  10. Development of Content Management System-based Web Applications

    NARCIS (Netherlands)

    Souer, J.

    2012-01-01

    Web engineering is the application of systematic and quantifiable approaches (concepts, methods, techniques, tools) to cost-effective requirements analysis, design, implementation, testing, operation, and maintenance of high quality web applications. Over the past years, Content Management Systems

  11. Developing practical knowledge content of emergency nursing professionals.

    Science.gov (United States)

    Chu, Wen; Hsu, Li-Ling

    2011-06-01

    There is a paucity of published research on clinical or practical nursing knowledge. The ways that nurses acquire, develop, and maintain emergency room (ER) nursing care skills is a research area, in particular, that deserves further investigation. This study examined clinical setting learning processes to better understand the practical knowledge content of ER nurses. This study used a phenomenological approach and in-depth interviews of 10 nurses. Each participant had at least 3 years of ER experience. Researchers used Moustakas' method to analyze interview data. Findings were checked for credibility, transferability, dependability, and confirmability. The authors identified four major practical knowledge themes for ER professionals. These were (a) basic emergency treatment procedure routines and symptom management; (b) disease mechanisms, pharmacodynamics, and treatment responses; (c) newly identified diseases, updated emergency treatments and techniques, and medical treatment discussions; and (d) identifying nursing values including nursing attitudes and continuing patient care. Participants in this study had experience with the first three themes and successfully combined various types of nursing knowledge in their nursing care duties. Only few participants indicated experience with the fourth theme. Findings clarify that clinical or practical knowledge in ER nurses evolves first from declarative knowledge (e.g., basic emergency treatment routines and operating procedures) to procedural knowledge (e.g., instructions from supervisors, actual practice, and drills) to conditional knowledge (e.g., observation and treatment involving direct interactions with patients). Nurses should combine and apply the various knowledge types in their nursing practice to assess comprehensively each patient's condition and administer effective treatment and service.

  12. Content Model Use and Development to Redeem Thin Section Records

    Science.gov (United States)

    Hills, D. J.

    2014-12-01

    The National Geothermal Data System (NGDS) is a catalog of documents and datasets that provide information about geothermal resources located primarily within the United States. The goal of NGDS is to make large quantities of geothermal-relevant geoscience data available to the public by creating a national, sustainable, distributed, and interoperable network of data providers. The Geological Survey of Alabama (GSA) has been a data provider in the initial phase of NGDS. One method by which NGDS facilitates interoperability is through the use of content models. Content models provide a schema (structure) for submitted data. Schemas dictate where and how data should be entered. Content models use templates that simplify data formatting to expedite use by data providers. These methodologies implemented by NGDS can extend beyond geothermal data to all geoscience data. The GSA, using the NGDS physical samples content model, has tested and refined a content model for thin sections and thin section photos. Countless thin sections have been taken from oil and gas well cores housed at the GSA, and many of those thin sections have related photomicrographs. Record keeping for these thin sections has been scattered at best, and it is critical to capture their metadata while the content creators are still available. A next step will be to register the GSA's thin sections with SESAR (System for Earth Sample Registration) and assign an IGSN (International Geo Sample Number) to each thin section. Additionally, the thin section records will be linked to the GSA's online record database. When complete, the GSA's thin sections will be more readily discoverable and have greater interoperability. Moving forward, the GSA is implementing use of NGDS-like content models and registration with SESAR and IGSN to improve collection maintenance and management of additional physical samples.

  13. Development of Usability Criteria for E-Learning Content Development Software

    Science.gov (United States)

    Celik, Serkan

    2012-01-01

    Revolutionary advancements have been observed in e-learning technologies though an amalgamated evaluation methodology for new generation e-learning content development tools is not available. The evaluation of educational software for online use must consider its usability and as well as its pedagogic effectiveness. This study is a first step…

  14. Learning About Semi Conductors for Teaching—the Role Played by Content Knowledge in Pedagogical Content Knowledge (PCK) Development

    Science.gov (United States)

    Rollnick, Marissa

    2017-08-01

    This study focuses on how teachers learn to teach a new topic and the role played by their developing content knowledge as they teach. The paper is based on seven high school science teachers' studies on the teaching of semiconductors, at the time a new topic in the curriculum. Analysis of artefacts such as teacher concept maps, video recordings of lessons, journals and other classroom-based evidence shows how the extent and type of teachers' content knowledge informed their choice of teaching approaches and how their learning of content took place alongside the development of teaching strategies. The development of content knowledge was combined with increased understanding of how to teach the topic in almost all cases. Evidence of development of teachers' PCK was found in their increased ability to design teaching strategies, and their use of representations and suitable assessment tasks for their lessons. Some specific common teaching strategies were identified across the teachers. These strategies could add to the canon of teachers' topic - specific professional knowledge for semiconductors. The study provides increased understanding of how teachers simultaneously master content and its teaching and how mediated self-reflection is a fruitful approach for assisting teachers to learn to teach a new topic.

  15. Amylose content decreases during tuber development in potato.

    Science.gov (United States)

    Jansky, Shelley; Fajardo, Diego

    2016-10-01

    Potato starch is composed primarily of amylopectin and amylose in an approximately 3:1 ratio. Amylose is considered to be nutritionally desirable in North American and European markets, so there is interest in finding strategies to increase the amylose content of potato starch. There is also interest in marketing 'baby' potatoes, which are harvested when they are physiologically immature. This study was carried out to determine weekly changes in amylose content in potato tubers of 11 North American cultivars during the growing season. The trial was repeated across 3 years. We determined that amylose content is highest early and it decreases in a linear fashion as the growing season progresses. Mean amylose content across cultivars and years declined from 30.0% in late June to 26.8% in late August. The rate of decrease varied across years, with slopes of linear regression plots ranging from -0.17 in 2012 to -0.74 in 2011. Amylose content in tuber starch varied among cultivars, with the highest levels observed in Ranger Russet (30.7%) and White Pearl (31.6%); it was lowest in Kennebec (25.7%) and Langlade (25.6%). This study adds to a growing body of literature on the nutritional value of immature potato tubers. In addition to having higher levels of some phytonutrients, as reported in other studies, immature tubers have a higher proportion of amylose in the starch. This is nutritionally desirable in affluent regions where high fiber content is more important than calories from carbohydrates. Published 2016. This article is a U.S. Government work and is in the public domain in the USA. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  16. Developing Technological Pedagogical Content Knowledge (TPACK) in Animal Physiology

    Science.gov (United States)

    Pusparini, F.; Riandi, R.; Sriyati, S.

    2017-09-01

    The purpose of this study is to describe preservice teacher’s learning during lecturing Animal Physiology and investigate it’s impact on preservice teacher’s technological pedagogical content knowledge (TPACK). How was the lecturing process can improve TPACK of preservice teacher on Biology education espescially in Animal Physiology. There are four experiment classes using Solomon four group design, there are pedagogic treatment, content treatment and technological treatment, the last class without any treatment. Both quantitative and qualitative data were collected. Quantitative data were collected through a questionaire of TPACK. Qualitative data were collected through a lesson plan and teaching simulation. Findings has revealed that participants experienced significant gains in all TPACK constructs. Both of pedagogic and technology treatment is better than others, but pedagogical treatment didn’t also increase PCK most of participants. Findings has implications for teacher education programs to be a professional teachers and for researchers interested.

  17. Development of Content Management System-based Web Applications

    OpenAIRE

    Souer, J.

    2012-01-01

    Web engineering is the application of systematic and quantifiable approaches (concepts, methods, techniques, tools) to cost-effective requirements analysis, design, implementation, testing, operation, and maintenance of high quality web applications. Over the past years, Content Management Systems (CMS) have emerged as an important foundation for the web engineering process. CMS can be defined as a tool for the creation, editing and management of web information in an integral way. A CMS appe...

  18. CONTENT MANAGEMENT SYSTEM FOR E-COMMERCE WEBSITE DEVELOPMENT

    OpenAIRE

    Neeraj Rohilla

    2017-01-01

    In today’s world one of the most growing areas is online selling and purchasing of goods and services which we generally call as E-commerce business. With this massive growth of global ecommerce market, the number of available Content Management Systems (CMS) and ecommerce platforms has grown as well. The aim of this research paper is to make a comparative study between many widely used open sources CMSs used for e-commerce website. This comparison will guide which CMS can be selected for set...

  19. Promoting pedagogical content knowledge development for early career secondary teachers in science and technology using content representations

    Science.gov (United States)

    Williams, John; Eames, Chris; Hume, Anne; Lockley, John

    2012-11-01

    Background: This research addressed the key area of early career teacher education and aimed to explore the use of a 'content representation' (CoRe) as a mediational tool to develop early career secondary teacher pedagogical content knowledge (PCK). This study was situated in the subject areas of science and technology, where sound teacher knowledge is particularly important to student engagement. Purpose: The study was designed to examine whether such a tool (a CoRe), co-designed by an early career secondary teacher with expert content and pedagogy specialists, can enhance the PCK of early career teachers. The research questions were: How can experts in content and pedagogy work together with early career teachers to develop one science topic CoRe and one technology topic CoRe to support the development of PCK for early career secondary teachers? How does the use of a collaboratively designed CoRe affect the planning of an early career secondary teacher in science or technology? How has engagement in the development and use of an expert-informed CoRe developed an early career teacher's PCK? Sample: The research design incorporated a unique partnership between two expert classroom teachers, two content experts, four early career teachers, and four researchers experienced in science and technology education. Design: This study employed an interpretivist-based methodology and an action research approach within a four-case study design. Data were gathered using qualitative research methods focused on semi-structured interviews, observations and document analysis. Results: The study indicated that CoRes, developed through this collaborative process, helped the early career teachers focus on the big picture of the topic, emphasize particularly relevant areas of content and consider alternative ways of planning for their teaching. Conclusions: This paper presents an analysis of the process of CoRe development by the teacher-expert partnerships and the effect that had on

  20. Development of the neutron technology for measuring the moisture content in China

    International Nuclear Information System (INIS)

    Zhao Jingwu; Liu Shengkang; Zhang Zhiping

    2011-01-01

    According to measuring mode (in-hopper, surface, sampling neutron moisture gauge), the development and application of neutron moisture gauge in china were introduced, which include the following course from only measuring moisture content of soil to monitoring moisture content of farmland and saving water for irrigating farmland, from measuring moisture content of pellet to coke and coal material, from only measuring moisture content to computerized neutron moisture gauges with density compensation and o f high precision. (authors)

  1. Developing cross-cultural healthcare workers: content, process and mentoring

    Directory of Open Access Journals (Sweden)

    Mark A Strand

    2016-01-01

    Full Text Available Career service in cross-cultural healthcare mission work is the ambition of many people around the world. However, premature termination of this expected long-term service mitigates against achieving the goals of the individual and the organization. The lingering challenge of high rates of missionary attrition impacts the long-term effectiveness of the work and the health and well-being of the workers. One of the keys to reducing premature attrition is cross-cultural training for these individuals, provided it offers the right content, through the best medium, at the time of greatest perceived need by the missionary. This paper applies the Dreyfus Model of skills acquisition to the process of mentoring career healthcare missionaries in a progressive manner, utilizing a mentoring method. These missionaries can flourish in their work and more effectively achieve their individual and organizational goals through strategic mentorship that clearly defines a pathway for growing their cross-cultural skills.

  2. 23 CFR 450.216 - Development and content of the statewide transportation improvement program (STIP).

    Science.gov (United States)

    2010-04-01

    ... Programming § 450.216 Development and content of the statewide transportation improvement program (STIP). (a... Equity Bonus funds; (5) Emergency relief projects (except those involving substantial functional...

  3. The Analysis of Sustainable Development Content in the Syllabus of Environmental Knowledge and Plants Ecology Lecture

    Science.gov (United States)

    Putra, A.; Rahmat, A.; Redjeki, S.

    2017-09-01

    This research aims to find out how much the content of sustainable development exist in the content of environmental knowledge and plant ecology courses. The focus indicators of sustainable development indicators is the environment. This research is a qualitative research type with qualitative descriptive approach. The analyzed variables are only 2 courses, which are environmental knowledge and plants ecology. The results showed that the syllabus contents analysis of environmental knowledge and plants ecology courses in private Lembaga Pendidikan Tenaga Kependidikan (LPTK) in the province of Nusa Tenggara Barat is already good enough and the sustainable development contents is very large, almost all syllabus contents has already prioritize the sustainable development load of both the subject of environmental knowledge and plants ecology, although there are still some syllabus contents that was not includes sustainable development load, but the percentage is quite small, especially in the course of Plant Ecology.

  4. Cultural Challenges in Developing E-Learning Content

    OpenAIRE

    Marianne Amir Azer; Ahmed Mostafa El-Sherbini

    2011-01-01

    Education is an important component of any nation’s development process. Society has been credited with creating technology, but technology is simultaneously creating society. One of the key benefits of such technology creation includes learning and curriculum development, which is otherwise referred to as e-leaning, and more appropriately referred to as global e-learning. Global e-learning raises some implications, which include communication, culture, and technology, that must be addressed ...

  5. Cull sow knife-separable lean content evaluation at harvest and lean mass content prediction equation development.

    Science.gov (United States)

    Abell, Caitlyn E; Stalder, Kenneth J; Hendricks, Haven B; Fitzgerald, Robert F

    2012-07-01

    The objectives of this study were to develop a prediction equation for carcass knife-separable lean within and across USDA cull sow market weight classes (MWC) and to determine carcass and individual primal cut knife separable lean content from cull sows. There were significant percent lean and fat differences in the primal cuts across USDA MWC. The two lighter USDA MWC had a greater percent carcass lean and lower percent fat compared to the two heavier MWC. In general, hot carcass weight explained the majority of carcass lean variation. Additionally, backfat was a significant variation source when predicting cull sow carcass lean. The findings support using a single lean prediction equation across MWC to assist processors when making cull sow purchasing decisions and determine the mix of animals from various USDA MWC that will meet their needs when making pork products with defined lean:fat content. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. A subsoil compaction database: its development, structure and content

    NARCIS (Netherlands)

    Trautner, A.; Akker, van den J.J.H.; Fleige, H.; Arvidsson, J.; Horn, R.

    2003-01-01

    A database which holds results of field and laboratory experiments on the impact of subsoil compaction on physical and mechanical soil parameters and on crop yields and environmental impact is being developed within the EU-sponsored concerted action (CA) project "Experiences with the impact of

  7. Development of method quantitative content of dihydroquercetin. Report 1

    Directory of Open Access Journals (Sweden)

    Олександр Юрійович Владимиров

    2016-01-01

    Full Text Available Today is markedly increasing scientific interest in the study of flavonoids in plant objects due to their high biological activity. In this regard, the urgent task of analytical chemistry is in developing available analytical techniques of determination for flavonoids in plant objects.Aim. The aim was to develop specific techniques of quantitative determination for dihydroquercetin and determination of its validation characteristics.Methods. The technique for photocolorimetric quantification of DQW, which was based on the specific reaction of cyanidine chloride formation when added zinc powder to dihydroquercetin solution in an acidic medium has been elaborated.Results. Photocolorimetric technique of determining flavonoids recalculating on DQW has been developed, its basic validation characteristics have been determined. The obtained metrological characteristics of photocolorimetric technique for determining DQW did not exceed admissibility criteria in accordance with the requirements of the State Pharmacopoeia of Ukraine.Conclusions. By the results of statistical analysis of experimental data, it has been stated that the developed technique can be used for quantification of DQW. Metrological data obtained indicate that the method reproduced in conditions of two different laboratories with confidence probability 95 % unit value deviation was 101,85±2,54 %

  8. Social contention in Denmark over alternative wind power development paths

    DEFF Research Database (Denmark)

    Nyborg, Sophie; Kirkegaard, Julia Kirch; Clausen, Laura Tolnov

    of Nørrekær Enge in Jutland. The paper traces protracted negotiations between a large energy company acting as wind farm developer who bought up dwellings to make space for extending an existing wind farm, land-owners, a farmers' association, and municipalities, as well as with an emergent coalition...

  9. Developing content standards for teaching research skills using a delphi method

    NARCIS (Netherlands)

    Schaaf, M.F. van der; Stokking, K.M.; Verloop, N.

    2005-01-01

    The increased attention for teacher assessment and current educational reforms ask for procedures to develop adequate content standards. For the development of content standards on teaching research skills, a Delphi method based on stakeholders’ judgments has been designed and tested. In three

  10. Cultural Challenges in Developing E-Learning Content

    Directory of Open Access Journals (Sweden)

    Marianne Amir Azer

    2011-03-01

    Full Text Available Education is an important component of any nation’s development process. Society has been credited with creating technology, but technology is simultaneously creating society. One of the key benefits of such technology creation includes learning and curriculum development, which is otherwise referred to as e-leaning, and more appropriately referred to as global e-learning. Global e-learning raises some implications, which include communication, culture, and technology, that must be addressed before successful implementation and outcome can occur. In this paper, we discuss cultural related issues such as culture influence on e-learning and the dimensions of cultural variability. In addition, we present the main challenges to provide e-learning opportunities. Finally, a case study for facing the cultural challenges is presented; this will be followed by concluding remarks at the end of this paper.

  11. Development Life Cycle and Tools for XML Content Models

    Energy Technology Data Exchange (ETDEWEB)

    Kulvatunyou, Boonserm [ORNL; Morris, Katherine [National Institute of Standards and Technology (NIST); Buhwan, Jeong [POSTECH University, South Korea; Goyal, Puja [National Institute of Standards and Technology (NIST)

    2004-11-01

    Many integration projects today rely on shared semantic models based on standards represented using Extensible Mark up Language (XML) technologies. Shared semantic models typically evolve and require maintenance. In addition, to promote interoperability and reduce integration costs, the shared semantics should be reused as much as possible. Semantic components must be consistent and valid in terms of agreed upon standards and guidelines. In this paper, we describe an activity model for creation, use, and maintenance of a shared semantic model that is coherent and supports efficient enterprise integration. We then use this activity model to frame our research and the development of tools to support those activities. We provide overviews of these tools primarily in the context of the W3C XML Schema. At the present, we focus our work on the W3C XML Schema as the representation of choice, due to its extensive adoption by industry.

  12. Interactive Media on Chagas Disease: Development and Content

    Directory of Open Access Journals (Sweden)

    Claudinei Caetano de Souza

    2013-10-01

    Full Text Available An interactive media on Chagas disease was developed as an educational tool, on the context of the scientific research and dissemination actions of the National Institute of Structural Biotechnology and Medicinal Chemistry in Infectious Diseases (INBEQMeDI. Different computational resources were used either in terms of hardware and software. The media contains 13 videos that range from 30 seconds to 4 minutes, all with information about Chagas disease, showing the social and economic aspects; the research made by the INBEQMeDI group; different aspects of the disease illustrated by slides arranged in a mobile carousel, and radio programs, with funny skits. The target audience for use of this feature is students aged 10 to 17 years. Teachers of areas of science and biology, through a partnership with the Agency of Education of the State of São Paulo, will be invited to plan a strategy for media use with their students.

  13. Learning from Rookie Mistakes: Critical Incidents in Developing Pedagogical Content Knowledge for Teaching Science to Teachers

    Science.gov (United States)

    Cite, Suleyman; Lee, Eun; Menon, Deepika; Hanuscin, Deborah L.

    2017-01-01

    While there is a growing literature focused on doctoral preparation for teaching about science teaching, rarely have recommendations extended to preparation for teaching science content to teachers. We three doctoral students employ self-study as a research methodology to investigate our developing pedagogical content knowledge for teaching…

  14. Developing a Questionnaire to Assess the Probability Content Knowledge of Prospective Primary School Teachers

    Science.gov (United States)

    Gómez-Torres, Emilse; Batanero, Carmen; Díaz, Carmen; Contreras, José Miguel

    2016-01-01

    In this paper we describe the development of a questionnaire designed to assess the probability content knowledge of prospective primary school teachers. Three components of mathematical knowledge for teaching and three different meanings of probability (classical, frequentist and subjective) are considered. The questionnaire content is based on…

  15. Development of Pre-Service Chemistry Teachers' Technological Pedagogical Content Knowledge

    Science.gov (United States)

    Cetin-Dindar, Ayla; Boz, Yezdan; Sonmez, Demet Yildiran; Celep, Nilgun Demirci

    2018-01-01

    In this study, a mixed-method design was employed to investigate pre-service chemistry teachers' Technological Pedagogical Content Knowledge (TPACK) development. For effective technology integration in instruction, knowledge about technology is not enough; teachers should have different knowledge types which are content, pedagogical, and…

  16. Multimedia Content Development as a Facial Expression Datasets for Recognition of Human Emotions

    Science.gov (United States)

    Mamonto, N. E.; Maulana, H.; Liliana, D. Y.; Basaruddin, T.

    2018-02-01

    Datasets that have been developed before contain facial expression from foreign people. The development of multimedia content aims to answer the problems experienced by the research team and other researchers who will conduct similar research. The method used in the development of multimedia content as facial expression datasets for human emotion recognition is the Villamil-Molina version of the multimedia development method. Multimedia content developed with 10 subjects or talents with each talent performing 3 shots with each capturing talent having to demonstrate 19 facial expressions. After the process of editing and rendering, tests are carried out with the conclusion that the multimedia content can be used as a facial expression dataset for recognition of human emotions.

  17. DEVELOPMENT OF USABILITY CRITERIA FOR E-LEARNING CONTENT DEVELOPMENT SOFTWARE

    Directory of Open Access Journals (Sweden)

    Serkan ÇELIK

    2012-04-01

    Full Text Available Revolutionary advancements have been observed in e-learning technologies though an amalgamated evaluation methodology for new generation e-learning content development tools is not available. The evaluation of educational software for online use must consider its usability and as well as its pedagogic effectiveness. This study is a first step towards the definition of criteria for evaluating e-learning tools. A preliminary user study involving a group of pre-service instructional designers, observed during their interaction with e-learning tools, is reported. Throughout the study, specific usability attributes of these e-learning tools were identified. Participants were assigned to rate the importance of functional and pedagogical competences proposed during the criteria development phase. The findings of the study revealed 31 evaluation criteria under the headings of technical, media, and assessment competences. Among the groups of benchmarks proposed and rated by the users, assessment was considered as the most important one while technical and media features were even.The following step was actual implemention of the usability criteria into evaluation of fifteen leading software used in e-learning across the world. Mostly, tools were observed as having limitations in terms of capabilities. Comparing to the other software, Captivate, Softchalk, and Lectora were regarded as outstanding tools by the participants. Following the discussion on the limitations of the study, some implications for further research were proposed.

  18. Design and Implementation Content Validity Study: Development of an instrument for measuring Patient-Centered Communication

    Directory of Open Access Journals (Sweden)

    Vahid Zamanzadeh

    2015-06-01

    Full Text Available ABSTRACT Introduction: The importance of content validity in the instrument psychometric and its relevance with reliability, have made it an essential step in the instrument development. This article attempts to give an overview of the content validity process and to explain the complexity of this process by introducing an example. Methods: We carried out a methodological study conducted to examine the content validity of the patient-centered communication instrument through a two-step process (development and judgment. At the first step, domain determination, sampling (item generation and instrument formation and at the second step, content validity ratio, content validity index and modified kappa statistic was performed. Suggestions of expert panel and item impact scores are used to examine the instrument face validity. Results: From a set of 188 items, content validity process identified seven dimensions includes trust building (eight items, informational support (seven items, emotional support (five items, problem solving (seven items, patient activation (10 items, intimacy/friendship (six items and spirituality strengthening (14 items. Content validity study revealed that this instrument enjoys an appropriate level of content validity. The overall content validity index of the instrument using universal agreement approach was low; however, it can be advocated with respect to the high number of content experts that makes consensus difficult and high value of the S-CVI with the average approach, which was equal to 0.93. Conclusion: This article illustrates acceptable quantities indices for content validity a new instrument and outlines them during design and psychometrics of patient-centered communication measuring instrument.

  19. Situational Requirements Engineering for the Development of Content Management System-based Web Applications

    NARCIS (Netherlands)

    Souer, J.; van de Weerd, I.; Versendaal, J.M.; Brinkkemper, S.

    2005-01-01

    Web applications are evolving towards strong content-centered Web applications. The development processes and implementation of these applications are unlike the development and implementation of traditional information systems. In this paper we propose WebEngineering Method; a method for developing

  20. A Scale for E-Content Preparation Skills: Development, Validity and Reliability

    Science.gov (United States)

    Tekin, Ahmet; Polat, Ebru

    2016-01-01

    Problem Statement: For an effective teaching and learning process it is critical to provide support for teachers in the development of e-content, and teachers should play an active role in this development. Purpose of the Study: The purpose of this study is to develop a valid and reliable Likert-type scale that will determine pre-service teachers'…

  1. Development of methods for determination of PAH based on measured CO-content

    International Nuclear Information System (INIS)

    Ingman, Rolf; Schuster, Robert

    2001-02-01

    The aim of the project 'Development of methods for determination of PAH based on measured CO-content' is to investigate the possibility to develop a method for continuous optimisation of NO x -emissions by decreased air ratio, without significant increase of polyaromatic hydrocarbons such as PAH. The general idea has been to find a indirect online method to predict the emissions of heavier hydrocarbons by: - creating a correlation between the content of CO and PAH, - controlling the air ratio by the CO-content, and - integrating the calculated PAH-content from CO-content. Today many boilers are operated with a low air ratio to minimise the NO x content and the NO x -fee. A low ratio increases the risk of high CO contents in the flue gas as well as increased contents of VOC and PAH. Other boilers are operated with high air ratios in order to minimise the CO content, which in some cases will result in unnecessary high NO x emissions. One of the main difficulties in optimising the air ratio to the most environmental friendly level is the lack of a suitable and well proven PAH instrument. There are today no available instruments for instantaneous and continuous measurement of PAH. PAH is normally measured as an average value during a period of at least one hour. It is not possible to detect short peaks. The development of the CO-method has been based on data from a CFB-boiler in Korsta in Sundsvall (Vaermeforskrapport 541). The data shows a clear correlation between THC and CO. The correlation seems to be mostly dependent of moisture content and load. The development presented in the report shows that it is possible to find a method to predict the PAH content from the CO-content in the flue gas. The next phase aims to improve and implement the method, by measurements and adaptation in a plant. The practical use of the method is as a tool to optimise the emission of CO, NO x , THC and PAH and/or to predict the PAH-emission during continuous operation

  2. Triiodothyronine and reverse triiodothyronine contents in human and pig thyroids at different periods of development

    International Nuclear Information System (INIS)

    Etling, Nicole; Gehin-Fouque, Francoise

    1978-01-01

    3,5,3'-triiodothyronine (T 3 ), and 3,3',5'-triiodothyronine (rT 3 ) were measured by radioimmunoassay in saline extracts of neonates and human adult thyroid tissues and of fetuses, Piglets and adult Swine thyroid tissues. In all these extracts, T 3 content was higher than rT 3 content whatever the period of development. Both triiodoamino acids represent a small percentage of the iodinated protein in thyroid tissues [fr

  3. Content knowledge development in a chemistry teacher preparation program: A current potentials and challenges

    Science.gov (United States)

    Widhiyanti, Tuszie; Treagust, David F.; Mocerino, Mauro; Vishnumolakala, Venkat

    2017-08-01

    One of the essential facets in teacher education program is the development of the teachers' content knowledge and it has been suggested by many scholars that the study to analyse the process of content knowledge development in teacher education program is necessary. Regarding this, the aim of this research is to evaluate the existing program of developing pre-service chemistry teachers' content knowledge, especially in the topic about the particulate nature of matter. The curriculum of content knowledge development was analysed using the forms of the curriculum evaluation (Akker, 1998; Goodlad, Klein, and Tye (1979); Treagust, 1987). Within this framework, the curriculum was evaluated in several aspects including the vision and intention of the curriculum as mentioned in the curriculum documents (intended curriculum), the users' interpretation and perception about the curriculum (perceived curriculum), the actual process of curriculum implementation (implemented curriculum), and the outcomes of the curriculum (achieved curriculum). According to the framework used for this study, the research combined qualitative and quantitative methods of data collection and the interpretation including document analysis, classroom observation, interviews, and two-tier diagnostic test. Through this research we examined the coherence among those aspects. The results reveal that although the content knowledge development is explicitly intended in a curriculum, its implementation and lecturers' perceptions give influence in the results as appear in pre-service teachers' achievements. In general, this research provides basic information about the effectiveness of the program including the challenges and the potentials for a reconsideration of the program in the future.

  4. Development of Pre-Service Physics Teachers' Pedagogical Content Knowledge (PCK) throughout Their Initial Training

    Science.gov (United States)

    Karal, Isik Saliha; Alev, Nedim

    2016-01-01

    The purpose of this study was to investigate the development of pre-service physics teachers' pedagogical content knowledge (PCK) on the subject of electricity and magnetism after their completion of physics and mathematics courses. A descriptive longitudinal development research was carried out with 13 pre-service teachers (PTs) who completed…

  5. Cross-Cultural Context, Content, and Design: Development of Courses in Global Topics Serving International Students

    Science.gov (United States)

    Van Hook, Steven R.

    2011-01-01

    This research was conducted in the development of courses for students from multiple nations at two California universities, applying cross-cultural tactics in course content and design. The paper examines the evolution of courses in Global Issues and Global Economics, including the theoretical foundations of socioeconomic development, how those…

  6. Changes in free amino acid content during naupliar development of the Calanoid copepod Acartia tonsa

    DEFF Research Database (Denmark)

    Rayner, Thomas Allan; Jørgensen, Niels Ole Gerslev; Drillet, Guillaume

    2017-01-01

    Changes in free amino acids (FAA) were investigated in the potentially important live feed and neritic copepod species Acartia tonsa during naupliar development. Total content of FAA in A. tonsa nauplii was around 17% of dry weight at first development stage, and declined to 6% for later stages...

  7. Student Opinions on Mobile Augmented Reality Application and Developed Content in Science Class

    Directory of Open Access Journals (Sweden)

    Damla Karagozlu

    2017-11-01

    Full Text Available As one of the most important branches of science, natural science studies have never lost their currency. The purpose of this study is to examine the development process of Augmented Reality contents which were developed using a design-based research method with the purpose of using it in teaching of natural science topics and to look into student evaluations. In the study which employed design-based research model, developed contents were applied, analysed and re-designed with students constantly. The study group of the research consisted of forty 7th grade students at a private college in 2016-2017 fall semester. Augmented reality contents developed for science teaching were evaluated by teachers and students as effective. According to the teacher and student opinions, it was concluded that augmented reality contents of science teaching developed during design-based research process was nice, easily applicable and useful. It can be said that while developing educative materials for students, applying design-based research model and paying attention to material design principles secures the effectiveness of the developed material.

  8. Football coaches’ development in Brazil: a focus on the content of learning

    Directory of Open Access Journals (Sweden)

    Alexandre Vinicius Bobato Tozetto

    2017-12-01

    Full Text Available Abstract AIM The aim of the study was to analyze the lifelong content of learning of coaches. METHODS Eight coaches inserted in an Elite Football Club participated. Rappaport Time Line and semi-structured interviews were used to obtain the data. The coaches’ learning was organized according to the theory of Lifelong Learning.1-4 RESULTS The coaches presented in their personal experiences, with their families and as athletes, content of learning such as “leadership development” and “formation of values”. In professional experiences, such as in academic training, coach assistants and even coaching, they are also reported as essential in obtaining content of learning (general and specific knowledge, training methods, leadership development, self-control. Finally, the reflexive process is considered by most coaches as a potentiator of learning, with interference on the “coach-athlete relationship”, “activity adjustment,” among other content of learning. CONCLUSION The content learned throughout the life were defined in certain episodes for presenting different meanings in the life of the coaches, in which they related to a new experience according to their biographies. Therefore, the various episodes offer coaches new experiences, in which they can incorporate, reinforce or renew the content about the coaching process and are responsible for the development of the coach.

  9. The Use of Local Wisdom Content in Secondary School: Problems And Creative Development

    Directory of Open Access Journals (Sweden)

    Khomkrit Channarong

    2017-09-01

    Full Text Available The study aimed to 1 study the use of local wisdom and its problems in secondary schools and 2 examine the pattern of development of local wisdom contents used in secondary schools. The study is a qualitative research which was done by examining related texts and documents as well as field research which was participated by 100 informants including government officers and local people. The data was collected by using questionnaire, observation form, interview, and focus group. The data was then analyzed according to the study and present by descriptive analysis approach. Research results show that The problems of using local wisdom contents are classified into the following aspects ; 1 Community aspect: learning and using local wisdom of the people in the community are related to local materials and ethnic ; 2 Curriculum aspect: the studied schools has curriculums conforming to government policies ; 3 Local wisdom instructors: local wisdom contents are instructed by local wisdom instructors in the studied schools. Local wisdom instructors from the university also take part in local wisdom education at the studied schools located in the same university campus ; 4 Current local wisdom learning aspect: all of the studied schools value the local wisdom education. Local wisdom contents are found enclosed in the schools’ visions and missions. Problems on using local wisdom contents are the deficiency of financial support from the government, neglect of school administrators, discontinuity of learners and instructors affected by their transference reasons, and insufficiency of local wisdom philosophers who could not keep continuative instruction in harvest season according to their initiative occupation of farming. For the development pattern of the use of local wisdom contents in the studied schools, it was found that local wisdom contents are creatively developed to increase the economic value in industry, handicraft, art, and Thai medicine. The

  10. Within-culture variation in the content of stereotypes: Application and development of the stereotype content model in an Eastern European culture.

    Science.gov (United States)

    Stanciu, Adrian; Cohrs, J Christopher; Hanke, Katja; Gavreliuc, Alin

    2017-01-01

    There is little and unsystematic evidence about whether the content of stereotypes can vary within a culture. Using the Stereotype Content Model (SCM) as a theoretical framework, in two studies we examined the content of stereotypes in an Eastern European culture, namely Romania. Data were collected from four regions prototypical in terms of economic and social development in Romania, and we examined whether the content of stereotypes varies across these regions. As expected, the findings confirm the applicability of the SCM in Romania to reveal culture-specific stereotypes and provide initial support for within-culture variation in the content of stereotypes. We discuss, in particular, possible reasons for two main findings: a strong one-dimensional structure of stereotypes, and regional differences in stereotype content.

  11. Changes in free amino acid content during naupliar development of the Calanoid copepod Acartia tonsa.

    Science.gov (United States)

    Rayner, Thomas Allan; Jørgensen, Niels Ole Gerslev; Drillet, Guillaume; Hansen, Benni Winding

    2017-08-01

    Changes in free amino acids (FAA) were investigated in the potentially important live feed and neritic copepod species Acartia tonsa during naupliar development. Total content of FAA in A. tonsa nauplii was around 17% of dry weight at first development stage, and declined to 6% for later stages. Relative to body-volume and biomass, the FAA content indicated possible volume-dependent changes. However, changes in FAA with osmolytic activity could not account for this decline in FAA content, but suggests that the decline reflected degradation of residual FAAs from the embryonic stage. Glutamic acid revealed the largest change in relative abundance during naupliar development and declined from 29.0% at first nauplius stage to 7.1% at later stages. The high FAA pool in early naupliar stages may be necessary for naupliar development due to an absence of feeding at first development stages. The high FAA content in early nauplii indicates that A. tonsa is a valuable source for nutritional energy for first-feeding fish larvae and should be further exploited for aquaculture purposes. Enhancements to FAA abundances in nauplii through manipulation of maternal diets could be of future interest, as copepod nauplii can contain a substantial pool of FAAs at first development stage. Copyright © 2017. Published by Elsevier Inc.

  12. Examining science teachers' pedagogical content knowledge in the context of a professional development program

    NARCIS (Netherlands)

    Wongsopawiro, Dirk Soenario

    2012-01-01

    This dissertation reports on the pedagogical content knowledge (PCK) of science teachers during a professional development program. This research intended to help us understand why and how teachers make their classroom decisions as they teach science. The main questions in this study were: What is

  13. Developing technological pedagogical content knowledge in pre-service mathematics teachers through collaborative design

    NARCIS (Netherlands)

    Agyei, D.D.; Voogt, Joke

    2012-01-01

    Although many studies have shown the need to pay attention to teachers' preparation for the integration of technology in classroom practice, most teachers in Ghana have not had any preparation that develops their technological pedagogical content knowledge (TPCK).This paper presents a case study of

  14. The Development of SCORM-Conformant Learning Content Based on the Learning Cycle Using Participatory Design

    Science.gov (United States)

    Su, C. Y.; Chiu, C. H.; Wang, T. I.

    2010-01-01

    This study incorporates the 5E learning cycle strategy to design and develop Sharable Content Object Reference Model-conformant materials for elementary science education. The 5E learning cycle that supports the constructivist approach has been widely applied in science education. The strategy consists of five phases: engagement, exploration,…

  15. Teachers' Professional Development: A Content Analysis about the Tendencies in Studies

    Science.gov (United States)

    Yurtseven, Nihal; Bademcioglu, Mehtap

    2016-01-01

    The purpose of this study is to carry out a content analysis about the studies on teachers' professional development and to determine the tendencies in these studies. Within this scope, 60 studies that were registered to Turkish National Thesis Centre and ProQuest database between the years 2005-2015 were examined. Of the 60 studies, 37 of them…

  16. Characterizing the Development of Specialized Mathematical Content Knowledge for Teaching in Algebraic Reasoning and Number Theory

    Science.gov (United States)

    Bair, Sherry L.; Rich, Beverly S.

    2011-01-01

    This article characterizes the development of a deep and connected body of mathematical knowledge categorized by Ball and Bass' (2003b) model of Mathematical Knowledge for Teaching (MKT), as Specialized Content Knowledge for Teaching (SCK) in algebraic reasoning and number sense. The research employed multiple cases across three years from two…

  17. Development and content validation of performance assessments for endoscopic third ventriculostomy

    NARCIS (Netherlands)

    Breimer, Gerben E.; Haji, Faizal A.; Hoving, Eelco W; Drake, James M.

    This study aims to develop and establish the content validity of multiple expert rating instruments to assess performance in endoscopic third ventriculostomy (ETV), collectively called the Neuro-Endoscopic Ventriculostomy Assessment Tool (NEVAT). The important aspects of ETV were identified through

  18. Development of automatic image analysis methods for high-throughput and high-content screening

    NARCIS (Netherlands)

    Di, Zi

    2013-01-01

    This thesis focuses on the development of image analysis methods for ultra-high content analysis of high-throughput screens where cellular phenotype responses to various genetic or chemical perturbations that are under investigation. Our primary goal is to deliver efficient and robust image analysis

  19. Development of in-plant reference material for composition of chinese cabbage with certified selenium content

    Directory of Open Access Journals (Sweden)

    D. A. Chupahin

    2014-01-01

    Full Text Available In-plant reference material for composition of Chinese cabbage with certified selenium content was developed for accuracy control of the results of selenium determination and within-laboratory quality control of analytical work in the analysis of food raw material.

  20. Developing a Markup Language for Encoding Graphic Content in Plan Documents

    Science.gov (United States)

    Li, Jinghuan

    2009-01-01

    While deliberating and making decisions, participants in urban development processes need easy access to the pertinent content scattered among different plans. A Planning Markup Language (PML) has been proposed to represent the underlying structure of plans in an XML-compliant way. However, PML currently covers only textual information and lacks…

  1. Development and Nature of Preservice Chemistry Teachers' Pedagogical Content Knowledge for Nature of Science

    Science.gov (United States)

    Demirdögen, Betül; Hanuscin, Deborah L.; Uzuntiryaki-Kondakci, Esen; Köseoglu, Fitnat

    2016-01-01

    The purpose of this case study is to delve into the complexities of the early development of preservice chemistry teachers' science teaching orientations, knowledge of learners, knowledge of instructional strategies, and knowledge of assessment during a two-semester intervention designed to enhance their pedagogical content knowledge (PCK) for…

  2. Development of a new spectrophotometric method to determine the total aromatic contents in kerosene

    International Nuclear Information System (INIS)

    Harfoush, A.; shlewit, H.

    1996-12-01

    This developed spectrophotometric method is helpful to determine and control the total aromatic contents in kerosene, during the treatment process of kerosene with conc. H sup 2 SO sup 4 and P sup 2 O sup 5 to remove aromatics, which have negative effect on the solvent extraction coefficient KD of uranium from the Syrian phosphoric acid, where kerosene is used as diluent. this method is rapid according to others, and simply, using the standard curve prepared by the separated aromatics from the Syrian kerosene, A =f (C) at 272 nm, we can calculate the aromatic contents in the known samples. (author). 24 Refs., 5 Figs

  3. Developing pre-service science teachers' pedagogical content knowledge by using training program

    Science.gov (United States)

    Udomkan, Watinee; Suwannoi, Paisan

    2018-01-01

    A training program was developed for enhancing pre-service science teachers' pedagogical content knowledge (PCK). The pre-service science teachers are able to: understand science curriculum, knowledge of assessment in science, knowledge of students' understanding of science, instructional strategies and orientations towards science teaching, which is conceptualized as PCK [5]. This study examined the preservice science teachers' understandings and their practices which include five pre-service science teachers' PCK. In this study, the participants demonstrated their PCK through the process of the training program by writing content representations (CoRes), preparing the lesson plans, micro-teaching, and actual teaching respectively. All pre-service science teachers' performs were collected by classroom observations. Then, they were interviewed. The results showed that the pre-service science teachers progressively developed knowledge components of PCK. Micro-teaching is the key activities for developing PCK. However, they had some difficulties in their classroom teaching. They required of sufficient ability to design appropriate instructional strategies and assessment activities for teaching. Blending content and pedagogy is also a matter of great concern. The implication of this study was that science educators can enhance pre-service science teachers' PCK by fostering their better understandings of the instructional strategies, assessment activities and blending between content and pedagogy in their classroom.

  4. Construction and validation of clinical contents for development of learning objects.

    Science.gov (United States)

    Hortense, Flávia Tatiana Pedrolo; Bergerot, Cristiane Decat; Domenico, Edvane Birelo Lopes de

    2018-01-01

    to describe the process of construction and validation of clinical contents for health learning objects, aimed at patients in the treatment of head and neck cancer. descriptive, methodological study. The development of the script and the storyboard were based on scientific evidence and submitted to the appreciation of specialists for validation of content. The agreement index was checked quantitatively and the suggestions were qualitatively evaluated. The items described in the roadmap were approved by 99% of expert experts. The suggestions for adjustments were inserted in their entirety in the final version. The free-marginal kappa statistical test, for multiple evaluators, presented value equal to 0.68%, granting a substantial agreement. The steps taken in the construction and validation of the content for the production of educational material for patients with head and neck cancer were adequate, relevant and suitable for use in other subjects.

  5. Construction and validation of clinical contents for development of learning objects

    Directory of Open Access Journals (Sweden)

    Flávia Tatiana Pedrolo Hortense

    Full Text Available ABSTRACT Objective: to describe the process of construction and validation of clinical contents for health learning objects, aimed at patients in the treatment of head and neck cancer. Method: descriptive, methodological study. The development of the script and the storyboard were based on scientific evidence and submitted to the appreciation of specialists for validation of content. The agreement index was checked quantitatively and the suggestions were qualitatively evaluated. Results: The items described in the roadmap were approved by 99% of expert experts. The suggestions for adjustments were inserted in their entirety in the final version. The free-marginal kappa statistical test, for multiple evaluators, presented value equal to 0.68%, granting a substantial agreement. Conclusion: The steps taken in the construction and validation of the content for the production of educational material for patients with head and neck cancer were adequate, relevant and suitable for use in other subjects.

  6. Development of micro-coulometry for measuring oxygen content in copper oxides

    International Nuclear Information System (INIS)

    Sato, Fumiaki; Fujihara, Masaaki; Kambe, Shiro; Ishii, Osamu

    2006-01-01

    A micro-coulometry system was newly developed and employed for measuring the oxygen content in copper oxides using a reduced amount of material. To achieve this reduction in sample size, Ar flow rate, and coulometric current were optimized. When using 5.0 mg of YBa 2 Cu 3 O 6.71 , which is about 1/10 the amount used in conventional coulometry, the oxygen content was successfully determined to be 6.68 ± 0.03, Ar flow rate, and coulometric current were 0.1 l/min, and 1.0 mA, respectively. It was found to be necessary to continue to pass Ar through the solution before coulometry more than ten minutes and during the coulometric measurement. This method will be useful for measuring the oxygen content of oxide samples smaller than 10 mg, i.e. oxide materials produced in small quantities for electronic applications

  7. Commercial spices and industrial ingredients: evaluation of antioxidant capacity and flavonoids content for functional foods development

    Directory of Open Access Journals (Sweden)

    Marcela Roquim Alezandro

    2011-06-01

    Full Text Available The aim of this work was to evaluate spices and industrial ingredients for the development of functional foods with high phenolic contents and antioxidant capacity. Basil, bay, chives, onion, oregano, parsley, rosemary, turmeric and powdered industrial ingredients (β-carotene, green tea extract, lutein, lycopene and olive extract had their in vitro antioxidant capacity evaluated by means of the Folin-Ciocalteu reducing capacity and DPPH scavenging ability. Flavonoids identification and quantification were performed by High Performance Liquid Chromatography (HPLC. The results showed that spices presented a large variation in flavonoids content and in vitro antioxidant capacity, according to kind, brand and batches. Oregano had the highest antioxidant capacity and parsley had the highest flavonoid content. The industrial ingredient with the highest antioxidant capacity was green tea extract, which presented a high content of epigalocatechin gallate. Olive extract also showed a high antioxidant activity and it was a good source of chlorogenic acid. This study suggests that oregano, parsley, olive and green tea extract have an excellent potential for the development of functional foods rich in flavonoids as antioxidant, as long as the variability between batches/brands is controlled.

  8. Developing Accounting Information System Course Content for Iraqi Higher Education Institution: An Instrument Design

    Directory of Open Access Journals (Sweden)

    Naseem Yousif Hanna Lallo

    2013-07-01

    Full Text Available In ensuring that competent graduates are produced in the universities, the course used embedding knowledge in the students, mindsets needs to be effective. However, the unusual circumstances that happened in Iraq were affected on a universities course. The revolution in information technology (IT affects most of our activations. As a result, it is important to consider the impact of IT on accounting careers. Developing accenting information system course content can generate an accountant who is armed with the knowledge and skills before entering accounting job. Also the development process required instructors have characteristics that make the integrating process of IT knowledge components in AIS course content more smoothly. Iraq is the country facing many difficulties that makes its higher education institutions (HEIs suffered from un updated learning environment and technological backwardness. This causes a low level of accounting graduates’ knowledge and in turn leads to led to consider the Iraqi accountant incapable of working with international organizations and companies or conducting was it professionally. The aim of this paper is to explain the role of IT knowledge elements in developing AIS course content in Iraqi HEIs with considering the moderate effect of the instructors’ characteristics. Furthermore, this paper discusses the development and validation of the quantitative instrument (questionnaire for IT knowledge elements in Iraqi HEIs. Moreover, the reliability of the constructs is also discussed.

  9. A mHealth cardiac rehabilitation exercise intervention: findings from content development studies

    Directory of Open Access Journals (Sweden)

    Pfaeffli Leila

    2012-05-01

    Full Text Available Abstract Background Involving stakeholders and consumers throughout the content and study design ensures interventions are engaging and relevant for end-users. The aim of this paper is to present the content development process for a mHealth (mobile phone and internet-based cardiac rehabilitation (CR exercise intervention. Methods An innovative mHealth intervention was developed with patient input using the following steps: conceptualization, formative research, pre-testing, and pilot testing. Conceptualization, including theoretical and technical aspects, was undertaken by experts. For the formative component, focus groups and interviews with cardiac patients were conducted to discuss their perceptions of a mHealth CR program. A general inductive thematic approach identified common themes. A preliminary library of text and video messages were then developed. Participants were recruited from CR education sessions to pre-test and provide feedback on the content using an online survey. Common responses were extracted and compiled. An iterative process was used to refine content prior to pilot testing and conduct of a randomized controlled trial. Results 38 CR patients and 3 CR nurses participated in the formative research and 20 CR patients participated in the content pre-testing. Participants perceived the mHealth program as an effective approach to inform and motivate patients to exercise. For the qualitative study, 100% (n = 41 of participants thought it to be a good idea, and 11% of participants felt it might not be useful for them, but would be for others. Of the 20 participants who completed the online survey, 17 out of 20 (85% stated they would sign up to a program where they could receive information by video messages on a website, and 12 out of 20 (60% showed interest in a texting program. Some older CR patients viewed technology as a potential barrier as they were unfamiliar with text messaging or did not have mobile phones. Steps to

  10. Book Sprint: A new model for rapid book authoring and content development

    International Nuclear Information System (INIS)

    Zennaro, M.; Canessa, E.; Fonda, C.; Belcher, M.; Flickenger, R.

    2007-01-01

    We discuss our experiences and successes with the new 'Book Sprint' methodology for use in rapid authoring and content development for technical books and documentation, using a distributed team and appropriate on-line collaborative technologies. A sprint begins by assembling a group of domain experts for a short period of time-intensive content creation. The outline, scope, and approximate length of the book are established, and key contributors are identified. This is followed by remote and distributed work over a period of a few months, focussing on the bulk of the book. The Sprint Book methodology has already been used in the 'Wireless Networking in the Developing World' and 'Bandwidth Optimization and Management' books. Both of these are freely available under a Creative Commons License. (author)

  11. Wikis: Developing pre-service teachers’ leadership skills and knowledge of content standards

    Directory of Open Access Journals (Sweden)

    Angelia Reid-Griffin

    2016-03-01

    Full Text Available In this initial phase of our multi-year research study we set out to explore the development of leadership skills in our pre-service secondary teachers after using an online wiki, Wikispaces. This paper presents our methods for preparing a group of 13 mathematics and 3 science secondary pre-service teachers to demonstrate the essential knowledge, skills and dispositions of beginning teacher leaders. Our findings indicate the pre-service teachers' overall satisfaction with demonstrating leadership through collaborative practices. They were successful in these new roles as teacher/collaborator within the context of communication about content standards. Though the candidates participated in other collaborative tasks, this effort was noted for bringing together technology, content standards and leadership qualities that are critical for beginning teachers. Implications for addressing the preservice teachers' development of leadership skills, as they become professional teachers will be shared.

  12. Development of the in vivo measurement system of bone mineral content using monoenergetic gamma rays

    International Nuclear Information System (INIS)

    Nardocci, A.C.

    1990-08-01

    A system, developed for in vivo measurement of bone mineral content (BMC) using monoenergetic gamma-rays of 241 Am, is described. It presents a discussion of the theoretical and practical aspects of the technique, with details of acquisition and data processing and also discusses the calibration procedure used. The results obtained with in vivo measurements are presented and BMC values of clinically normal subjects and chronic renal patients are compared. (author)

  13. Website Babies Portal: development and evaluation of the contents regarding orofacial functions

    Science.gov (United States)

    CORRÊA, Camila de Castro; PAULETO, Adriana Regina Colombo; FERRARI, Deborah Viviane; BERRETIN-FELIX, Giédre

    2013-01-01

    Education mediated by technology facilitates the access to information and can reach more people, including a broader range of socio-economic groups and ages, and at a low-cost. The website "Babies Portal - Speech-Language Pathology/Audiology and Dentistry" (http://portaldosbebes.fob.usp.br) was developed to provide parents with information on communication procedure disorders and oral health, enabling them to prevent and identify any changes in development early while looking for the best treatment. Objective: The objective is to describe the development and evaluation of the content pertaining to the oral functions featured in the "Babies Portal". Methods: The first stage consisted of a literature review, development/selection of illustrations and an evaluation of the possible external links that could be available. In the second stage, 10 speech-language and hearing pathologists (group A) and five parents of babies (group B) evaluated the website via an online form, which included ethical and personal information and questions about the quality, technical information and comparative prior knowledge acquired after the access. In the first stage, there was the construction of five sections ("The Oral Functions", "Breastfeeding", "Food", "Pacifier, baby bottle and finger sucking" and "Breath") based on scientific studies, presenting objective information, content links prepared by the Ministry of Health and a Dentistry section in the "Babies Portal" website. Videos, static and dynamic images were also distributed throughout the sections. Results: Regarding the second stage, 90% of all speech-language and hearing pathologists judged a good/excellent quality for all sections and classified the technical quality as very good. By their turn, 88% of the parents (group B) reported that the website helped or helped very much in understanding the contents, and 80% rated the quality as good or excellent. Conclusions: Five sections concerning the oral functions were

  14. The Johns Hopkins model of psychological first aid (RAPID-PFA): curriculum development and content validation.

    Science.gov (United States)

    Everly, George S; Barnett, Daniel J; Links, Jonathan M

    2012-01-01

    There appears to be virtual universal endorsement of the need for and value of acute "psychological first aid" (PFA) in the wake of trauma and disasters. In this paper, we describe the development of the curriculum for The Johns Hopkins RAPID-PFA model of psychological first aid. We employed an adaptation of the basic framework for the development of a clinical science as recommended by Millon which entailed: historical review, theoretical development, and content validation. The process of content validation of the RAPID-PFA curriculum entailed the assessment of attitudes (confidence in the application of PFA interventions, preparedness in the application of PFA); knowledge related to the application of immediate mental health interventions; and behavior (the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise). Results of the content validation phase suggest the six-hour RAPID-PFA curriculum, initially based upon structural modeling analysis, can improve confidence in the application of PFA interventions, preparedness in the application of PFA, knowledge related to the application of immediate mental health interventions, and the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise.

  15. Development of format and contents of safety analysis report for the KNGR standard design

    International Nuclear Information System (INIS)

    Lee, J. H.; Kim, H. S.; Yun, Y. K. and others

    1999-01-01

    Referring to the USNRC Regulatory Guide 1.70 which has been used in the preparation of the SAR for conventional nuclear power plants, the draft guide for format and contents of the SAR for the KNGR standard design was developed based on new regulatory information related to advanced reactors. The draft guide will enable the regulator to make an effective and consistent review on the safety of the KNGR, when this draft guide is used, since the draft guide requires more specific and additional safety information for the standardized NPPs than RG 1.70. In addition, it is expected that the guide for the format and contents of the COL's SAR will be more easily developed using the draft guide suggested in this report. Also, the draft guide can serve as the Korean national guide, with the exception to some industry codes and standards. The experts' review will be performed during the next stage of the project to ensure the objectivity and consistency of the draft guide developed in this study. After reflecting the experts' comments in the guide and revising the contents, it will be utilized in the licensing activities for the KNGR standard design

  16. Content validity and reliability of test of gross motor development in Chilean children

    Directory of Open Access Journals (Sweden)

    Marcelo Cano-Cappellacci

    2015-01-01

    Full Text Available ABSTRACT OBJECTIVE To validate a Spanish version of the Test of Gross Motor Development (TGMD-2 for the Chilean population. METHODS Descriptive, transversal, non-experimental validity and reliability study. Four translators, three experts and 92 Chilean children, from five to 10 years, students from a primary school in Santiago, Chile, have participated. The Committee of Experts has carried out translation, back-translation and revision processes to determine the translinguistic equivalence and content validity of the test, using the content validity index in 2013. In addition, a pilot implementation was achieved to determine test reliability in Spanish, by using the intraclass correlation coefficient and Bland-Altman method. We evaluated whether the results presented significant differences by replacing the bat with a racket, using T-test. RESULTS We obtained a content validity index higher than 0.80 for language clarity and relevance of the TGMD-2 for children. There were significant differences in the object control subtest when comparing the results with bat and racket. The intraclass correlation coefficient for reliability inter-rater, intra-rater and test-retest reliability was greater than 0.80 in all cases. CONCLUSIONS The TGMD-2 has appropriate content validity to be applied in the Chilean population. The reliability of this test is within the appropriate parameters and its use could be recommended in this population after the establishment of normative data, setting a further precedent for the validation in other Latin American countries.

  17. NAD-content and metabolism in the mouse embryo and developing brain

    International Nuclear Information System (INIS)

    Beuningen, M. van; Streffer, C.; Beuningen, D. van

    1986-01-01

    Biochemical studies have shown that NAD is not only the coenzyme of dehydrogenase but also the substrate of poly-(ADPR)-synthetase which is involved in processes of cell proliferation and differentiation. The NAD and protein content was determined in the total embryo and in the CNS 9 to 13 days p.c. The embryos were X-irradiated 9 days p.c. The NAD content increased in the total mouse embryo during the early organogenesis. At the later period a decrease of the NAD content per mg protein was observed. This latter effect was apparently due to an increase of the NAD glycohydrolase activity. This enzyme degrades NAD. A similar development was observed in the developing mouse brain. However, the maximal NAD content per mg protein occurred on day 10 p.c. One of the enzyme activities, which are responsible for NAD synthesis, NMN-pyrophosphorylase, also increased in the brain at the same time. After the injection of C 14-nicotinamide, a precursor of NAD, it was observed that the radioactivity mainly appeared in nicotinamide and NAD. With progressing embryological development less nicotinamide was taken up by the embryonic tissue. When the embryos were X-irradiated on day 9 p.c. with 1.8 Gy the increase of NAD was considerably reduced during the next days, so that also the NAD level per mg protein was reduced. Also the NAD biosynthesis apparently decreased. This was shown again by the reduced NMN-pyrophosphorylase activity. The dose dependance of these effects was studied in the dose range 0.48-1.8 Gy. Two days p.r. most of the radiation effects were normalized again and at later periods even an overshoot of the enzyme activity was observed. The possible relevance of these effects for cell proliferation will be discussed. (orig.)

  18. Planning for Development in the Arab Gulf States: A content Analysis of Current Development Plans

    DEFF Research Database (Denmark)

    Hvidt, Martin

    2012-01-01

    Abstract: This paper analyses current development plans published by the GCC states (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) in order to explore the region’s future growth trajectory: what barriers to growth are foreseen and how can they be anticipated; what...

  19. Content Analysis of Online Undergraduate Student-Generated Questions and the Development of Its Creativity Indicators

    Directory of Open Access Journals (Sweden)

    Fu-Yun Yu

    2016-06-01

    Full Text Available In light of current research gaps in online student-generated questions (SGQ (as most studies on the content types, forms, and performance criteria of SGQ are done in math, adopting a structured format, using a paper-and-pencil form, and paying less attention to affective aspects, the purposes of this study are: first, to analyze the content, forms, and techniques of online SGQ via content analysis; second, to develop the creative indicators for online SGQ and establish the validity of the devised indicators. For the first purpose, 792 questions generated by 54 student teachers during online SGQ activities were subjected to content analysis. For the second purpose, another group of 40 student teachers completed a consensus questionnaire, and the data were analyzed via repeated measures, followed by post-hoc comparisons. Four major findings were obtained: 1 with regard to the contents of online SGQ, connections to personal daily life and future personal goals were frequently observed; 2 most participants took advantage of the formatting, color, and graphics features afforded in computer technologies during online SGQ to suit multiple purposes; 3 participants exhibited versatile skills during SGQ; 4 questions with different levels of creativity differed significantly in terms of novelty and interestingness indicators, supporting the validity of the devised indicators. Yet, no significant differences were found in the usefulness indicator, supporting the claim that novelty and interestingness do not necessarily compromise the perceived usefulness of the generated item. Based on the findings, suggestions for SGQ, creative teaching, and future research are provided.

  20. Qualitative Development and Content Validation of the PROMIS Pediatric Sleep Health Items.

    Science.gov (United States)

    Bevans, Katherine B; Meltzer, Lisa J; De La Motte, Anna; Kratchman, Amy; Viél, Dominique; Forrest, Christopher B

    2018-04-25

    To develop the Patient Reported Outcome Measurement Information System (PROMIS) Pediatric Sleep Health item pool and evaluate its content validity. Participants included 8 expert sleep clinician-researchers, 64 children ages 8-17 years, and 54 parents of children ages 5-17 years. We started with item concepts and expressions from the PROMIS Sleep Disturbance and Sleep Related Impairment adult measures. Additional pediatric sleep health concepts were generated by expert (n = 8), child (n = 28), and parent (n = 33) concept elicitation interviews and a systematic review of existing pediatric sleep health questionnaires. Content validity of the item pool was evaluated with item translatability review, readability analysis, and child (n = 36) and parent (n = 21) cognitive interviews. The final pediatric Sleep Health item pool includes 43 items that assess sleep disturbance (children's capacity to fall and stay asleep, sleep quality, dreams, and parasomnias) and sleep-related impairments (daytime sleepiness, low energy, difficulty waking up, and the impact of sleep and sleepiness on cognition, affect, behavior, and daily activities). Items are translatable and relevant and well understood by children ages 8-17 and parents of children ages 5-17. Rigorous qualitative procedures were used to develop and evaluate the content validity of the PROMIS Pediatric Sleep Health item pool. Once the item pool's psychometric properties are established, the scales will be useful for measuring children's subjective experiences of sleep.

  1. The development of high-content screening (HCS) technology and its importance to drug discovery.

    Science.gov (United States)

    Fraietta, Ivan; Gasparri, Fabio

    2016-01-01

    High-content screening (HCS) was introduced about twenty years ago as a promising analytical approach to facilitate some critical aspects of drug discovery. Its application has spread progressively within the pharmaceutical industry and academia to the point that it today represents a fundamental tool in supporting drug discovery and development. Here, the authors review some of significant progress in the HCS field in terms of biological models and assay readouts. They highlight the importance of high-content screening in drug discovery, as testified by its numerous applications in a variety of therapeutic areas: oncology, infective diseases, cardiovascular and neurodegenerative diseases. They also dissect the role of HCS technology in different phases of the drug discovery pipeline: target identification, primary compound screening, secondary assays, mechanism of action studies and in vitro toxicology. Recent advances in cellular assay technologies, such as the introduction of three-dimensional (3D) cultures, induced pluripotent stem cells (iPSCs) and genome editing technologies (e.g., CRISPR/Cas9), have tremendously expanded the potential of high-content assays to contribute to the drug discovery process. Increasingly predictive cellular models and readouts, together with the development of more sophisticated and affordable HCS readers, will further consolidate the role of HCS technology in drug discovery.

  2. Postnatal development of EEG patterns, catecholamine contents and myelination, and effect of hyperthyroidism in Suncus brain.

    Science.gov (United States)

    Takeuchi, T; Sitizyo, K; Harada, E

    1998-03-01

    The postnatal development of the central nervous system (CNS) in house musk shrew in the early stage of maturation was studied. The electroencephalogram (EEG) and visual evoked potential (VEP) in association with catecholamine contents and myelin basic protein (MBP) immunoreactivity were carried out from the 1st to the 20th day of postnatal age. Different EEG patterns which were specific to behavioral states (awake and drowsy) were first recorded on the 5th day, and the total power which was obtained by power spectrum analysis increased after this stage. The latencies of all peaks in VEP markedly shortened between the 5th and the 7th day. Noradrenalin (NA) content of the brain showed a slight increase after the 3rd day, and reached maximum levels on the 7th day, which was delayed a few days compared to dopamine (DA). In hyperthyroidism, the peak latency of VEP was shortened and biosynthesis of NA in cerebral cortex and DA in hippocampus was accelerated. The most obvious change in MBP-immunoreactivity of the telencephalon occurred from the 7th to the 10th day. These morphological changes in the brain advanced at the identical time-course to those in the electrophysiological development and increment of DA and NA contents.

  3. Effect of the science teaching advancement through modeling physical science professional development workshop on teachers' attitudes, beliefs and content knowledge and students' content knowledge

    Science.gov (United States)

    Dietz, Laura

    The Science Teaching Advancement through Modeling Physical Science (STAMPS) professional development workshop was evaluated for effectiveness in improving teachers' and students' content knowledge. Previous research has shown modeling to be an effective method of instruction for improving student and teacher content knowledge, evidenced by assessment scores. Data includes teacher scores on the Force Concept Inventory (FCI; Hestenes, Wells, & Swackhamer, 1992) and the Chemistry Concept Inventory (CCI; Jenkins, Birk, Bauer, Krause, & Pavelich, 2004), as well as student scores on a physics and chemistry assessment. Quantitative data is supported by teacher responses to a post workshop survey and classroom observations. Evaluation of the data shows that the STAMPS professional development workshop was successful in improving both student and teacher content knowledge. Conclusions and suggestions for future study are also included.

  4. [Development and test of a wheat chlorophyll, nitrogen and water content meter].

    Science.gov (United States)

    Yu, Bo; Sun, Ming; Han, Shu-Qing; Xia, Jin-Wen

    2011-08-01

    A portable meter was developed which can detect chlorophyll, nitrogen and moisture content of wheat leaf simultaneously, and can supply enough data for guiding fertilization and irrigation. This meter is composed of light path and electronic circuit. And this meter uses 660, 940 and 1450 nm LED together with narrow band filters as the active light source. The hardware circuit consists of micro-controller, LED drive circuit, detector, communication circuit, keyboard and LCD circuit. The meter was tested in the field and performed well with good repeatability and accuracy. The relative errors of chlorophyll and nitrogen test were about 10%, relative error for water content was 4%. The coefficients of variation of the three indices were all below 1.5%. All of these prove that the meter can be applied under the field condition to guide the wheat production.

  5. Development and Validation of an Enzymatic Method To Determine Stevioside Content from Stevia rebaudiana.

    Science.gov (United States)

    Udompaisarn, Somsiri; Arthan, Dumrongkiet; Somana, Jamorn

    2017-04-19

    An enzymatic method for specific determination of stevioside content was established. Recombinant β-glucosidase BT_3567 (rBT_3567) from Bacteroides thetaiotaomicron HB-13 exhibited selective hydrolysis of stevioside at β-1,2-glycosidic bond to yield rubusoside and glucose. Coupling of this enzyme with glucose oxidase and peroxidase allowed for quantitation of stevioside content in Stevia samples by using a colorimetric-based approach. The series of reactions for stevioside determination can be completed within 1 h at 37 °C. Stevioside determination using the enzymatic assay strongly correlated with results obtained from HPLC quantitation (r 2 = 0.9629, n = 16). The percentages of coefficient variation (CV) of within day (n = 12) and between days (n = 12) assays were lower than 5%, and accuracy ranges were 95-105%. This analysis demonstrates that the enzymatic method developed in this study is specific, easy to perform, accurate, and yields reproducible results.

  6. Color development and acrylamide content of pre-dried potato chips

    DEFF Research Database (Denmark)

    Pedreschi, Franco; León, Jorge; Mery, Domingo

    2007-01-01

    The objective of this work was to study the development of color formation in pre-dried potato slices during frying and acrylamide formation in the final potato chips. Color measurement was done by using an inexpensive computer vision technique which allowed quantifying representatively...... and precisely the color of complex surfaces such as those of potato chips in L*a*b* units from RGB images. Prior to frying, potato slices (Desiree variety, diameter: 37 mm, width: 2.2 mm) were blanched in hot water at 85 degrees C for 3.5 min. Unblanched slices were considered as the control. Slices of the same...... dimensions were blanched as in the previous step, and then air-dried until reaching a moisture content of 60% (wet basis). These samples were called pre-dried potato slices. Potato slices were fried at 120 degrees C, 140 degrees C, 160 degrees C and 180 degrees C until reaching moisture contents of similar...

  7. Development of transgenic Brassica juncea lines for reduced seed sinapine content by perturbing phenylpropanoid pathway genes.

    Directory of Open Access Journals (Sweden)

    Sachin Kajla

    Full Text Available Sinapine is a major anti-nutritive compound that accumulates in the seeds of Brassica species. When ingested, sinapine imparts gritty flavuor in meat and milk of animals and fishy odor to eggs of brown egg layers, thereby compromising the potential use of the valuable protein rich seed meal. Sinapine content in Brassica juncea germplasm ranges from 6.7 to 15.1 mg/g of dry seed weight (DSW which is significantly higher than the prescribed permissible level of 3.0 mg/g of DSW. Due to limited natural genetic variability, conventional plant breeding approach for reducing the sinapine content has largely been unsuccessful. Hence, transgenic approach for gene silencing was adopted by targeting two genes-SGT and SCT, encoding enzymes UDP- glucose: sinapate glucosyltransferase and sinapoylglucose: choline sinapoyltransferase, respectively, involved in the final two steps of sinapine biosynthetic pathway. These two genes were isolated from B. juncea and eight silencing constructs were developed using three different RNA silencing approaches viz. antisense RNA, RNAi and artificial microRNA. Transgenics in B. juncea were developed following Agrobacterium-mediated transformation. From a total of 1232 independent T0 transgenic events obtained using eight silencing constructs, 25 homozygous lines showing single gene inheritance were identified in the T2 generation. Reduction of seed sinapine content in these lines ranged from 15.8% to 67.2%; the line with maximum reduction had sinapine content of 3.79 mg/g of DSW. The study also revealed that RNAi method was more efficient than the other two methods used in this study.

  8. Developing brief fatigue short forms calibrated to a common mathematical metric: is content-balancing important?

    Directory of Open Access Journals (Sweden)

    Karon F Cook

    2010-08-01

    Full Text Available Karon F Cook1, Seung W Choi2, Kurt L Johnson1, Dagmar Amtmann11Department of Rehabilitation Medicine, University of Washington, Seattle, WA; 2Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: There are clinical and research settings in which concerns about respondent burden make the use of longer self-report measures impractical. Though computer adaptive testing provides an efficient strategy for measuring patient reported outcomes, the requirement of a computer interface makes it impractical for some settings. This study evaluated how well brief short forms, constructed from a longer measure of patient reported fatigue, reproduced scores on the full measure. When the items of an item bank are calibrated using an item response theory model, it is assumed that the items are fungible units. Theoretically, there should be no advantage to balancing the content coverage of the items. We compared short forms developed using a random item selection process to short forms developed with consideration of the items relation to subdomains of fatigue (ie, physical and cognitive fatigue. Scores on short forms developed using content balancing more successfully predicted full item bank scores than did scores on short forms developed by random selection of items.Keywords: psychometrics, outcomes, quality of life, measurement, fatigue

  9. How international oil and gas companies respond to local content policies in petroleum-producing developing countries: A narrative enquiry

    International Nuclear Information System (INIS)

    Ngoasong, Michael Zisuh

    2014-01-01

    This paper uses narrative analysis to critically examine the business practices used by five international oil and gas companies (IOCs) (Chevron, ExxonMobil, Shell, BP and Total) to respond to local content policies in petroleum-producing developing countries (Nigeria, Angola, Venezuela, Kazakhstan, Brazil, Indonesia, Yemen and Indonesia) during the period 2000–2012. The business practices include the formulation of local content strategies that are implemented through programmes and initiatives aimed at developing and using host country suppliers and workforce. Such practices and the narratives used to communicate them implicitly reflect the context in which the effectiveness of local content policies on economic development can be assessed. By comparing and contrasting the narratives across the five IOCs in relation to the wider literature, four emergent narrative strategies justifying the business practices of IOCs are identified and discussed. They include: (1) direct engagement to renegotiate local content requirements with governments, (2) legal compliance framework, (3) the business case for local content strategies, and (4) corporate social responsibility (CSR) initiatives. The conclusion considers the policy implications of these findings for local content development in petroleum-producing developing countries. - Highlights: • Local content policies define the local context that shape IOCs’ business practices. • Provides a narrative analysis of the business practices of IOCs in developing countries. • IOCs use four narrative strategies to relate their business practices to local content policies. • The business practices of IOCs can determine the effectiveness of local content policies

  10. ESIP's Emerging Provenance and Context Content Standard Use Cases: Developing Examples and Models for Data Stewardship

    Science.gov (United States)

    Ramdeen, S.; Hills, D. J.

    2013-12-01

    Earth science data collections range from individual researchers' private collections to large-scale data warehouses, from computer-generated data to field or lab based observations. These collections require stewardship. Fundamentally, stewardship ensures long term preservation and the provision of access to the user community. In particular, stewardship includes capturing appropriate metadata and documentation--and thus the context of the data's creation and any changes they underwent over time --to enable data reuse. But scientists and science data managers must translate these ideas into practice. How does one balance the needs of current and (projected) future stakeholders? In 2011, the Data Stewardship Committee (DSC) of the Federation of Earth Science Information Partners (ESIP) began developing the Provenance and Context Content Standard (PCCS). As an emerging standard, PCCS provides a framework for 'what' must be captured or preserved as opposed to describing only 'how' it should be done. Originally based on the experiences of NASA and NOAA researchers within ESIP, the standard currently provides data managers with content items aligned to eight key categories. While the categories and content items are based on data life cycles of remote sensing missions, they can be generalized to cover a broader set of activities, for example, preservation of physical objects. These categories will include the information needed to ensure the long-term understandability and usability of earth science data products. In addition to the PCCS, the DSC is developing a series of use cases based on the perspectives of the data archiver, data user, and the data consumer that will connect theory and practice. These cases will act as specifications for developing PCCS-based systems. They will also provide for examination of the categories and content items covered in the PCCS to determine if any additions are needed to cover the various use cases, and also provide rationale and

  11. Improving Instructional Leadership through the Development of Leadership Content Knowledge: The Case of Principal Learning in Algebra

    Science.gov (United States)

    Steele, Michael D.; Johnson, Kate R.; Otten, Samuel; Herbel-Eisenmann, Beth A.; Carver, Cynthia L.

    2015-01-01

    Instructional leadership is integral to improving mathematics teaching in secondary schools. However, administrators often lack sufficient content knowledge in mathematics to be effective in this role. This study examined the impact of professional development focused on developing leadership content knowledge in algebra. Data included written…

  12. Photosynthesis rate, chlorophyll content and initial development of physic nut without micronutrient fertilization

    Directory of Open Access Journals (Sweden)

    Elcio Ferreira dos Santos

    2013-10-01

    Full Text Available Few studies in Brazil have addressed the need for micronutrients of physic nut focusing on physiological responses, especially in terms of photosynthesis. The objective of this study was to evaluate the effects of omission of boron (B, copper (Cu, iron (Fe, manganese (Mn and zinc (Zn on Jatropha curcas L.. The experimental design was a randomized block with four replications. The treatments were complete solution (control and solution without B, Cu, Fe, Mn, and Zn. We evaluated the chlorophyll content (SPAD units, photosynthetic rate, dry matter production and accumulation of micronutrients in plants, resulting from different treatments. The first signs of deficiency were observed for Fe and B, followed by Mn and Zn, while no symptoms were observed for Cu deficiency. The micronutrient omission reduced the dry matter yield, chlorophyll content and photosynthetic rate of the plants differently for each omitted nutrient. It was, however, the omission of Fe that most affected the development of this species in all parameters evaluated. The treatments negatively affected the chlorophyll content, evaluated in SPAD units, and the photosynthetic rate, except for the omission of B. However this result was probably due to the concentration effect, since there was a significant reduction in the dry matter production of B-deficient plants.

  13. Maritime Content in Indonesian History Education: The Development and Alternative Solution

    Directory of Open Access Journals (Sweden)

    Wasino Wasino

    2017-12-01

    Full Text Available For a long time ago, Indonesia was identified as maritime country. The collective memory remembered from several islands in Indonesia shows that Indonesia is a large maritime space. The original name of the country was Nusantara, (called archipelago in English. From historical data in some location, there are some evidences about the glorious of the maritime kingdom in the continent. However, maritime perspective is not to be ‘important issue” in the mind of Indonesian people nowadays. History education makes an important rule at the moment. Indonesian independence needs history education based on political perspective, especially to enhance nationalism. The orientation is continued until the New Order, and it is especially focused on the rule of Indonesia military. Reformation since 1998 should make democratization in Indonesian history teaching, but the reality, the tradition of writer in history education, was still stagnant. The content of maritime history in Indonesian History Education still become a big problem. This paper aims to analyze the development of the maritime content in Indonesian History education at school and to give the new alternative in teaching history based on maritime content. The alternative curriculum based on local competitiveness in maritime history related with regional and global region, is the best solution for it.

  14. Developing biology teachers' pedagogical content knowledge through learning study: the case of teaching human evolution

    Science.gov (United States)

    Bravo, Paulina; Cofré, Hernán

    2016-11-01

    This work explores how pedagogical content knowledge (PCK) on evolution was modified by two biology teachers who participated in a professional development programme (PDP) that included a subsequent follow-up in the classroom. The PDP spanned a semester and included activities such as content updates, collaborative lesson planning, and the presentation of planned lessons. In the follow-up part, the lessons were videotaped and analysed, identifying strategies, activities, and conditions based on student learning about the theory of evolution. Data were collected in the first round with an interview before the training process, identifying these teachers' initial content representation (CoRe) for evolution. Then, a group interview was conducted after the lessons, and, finally, an interview of stimulated recall with each teacher was conducted regarding the subject taught to allow teachers to reflect on their practice (final CoRe). This information was analysed by the teachers and the researchers, reflecting on the components of the PCK, possible changes, and the rationale behind their actions. The results show that teachers changed their beliefs and knowledge about the best methods and strategies to teach evolution, and about students' learning obstacles and misconceptions on evolution. They realised how a review of their own practices promotes this transformation.

  15. Compare the user interface of digital libraries\\' websites between the developing and developed countries in content analysis method

    Directory of Open Access Journals (Sweden)

    Gholam Abbas Mousavi

    2017-03-01

    Full Text Available Purpose: This study performed with goals of determining the Items in designing and developing the user interface of digital libraries' websites and to determine the best digital libraries' websites and discuss their advantages and disadvantages; to analyze and compare digital libraries' websites in developing countries with those in the developed countries. Methodology: to do so, 50 digital libraries' websites were selected by purposive sampling method. By analyzing the level of development of the countries in the sample regarding their digital libraries' websites, 12 websites were classified as belonging to developing and 38 countries to developed counties. Then, their content was studied by using a qualitative content analysis. The study was conducted by using a research-constructed checklist containing 12 main categories and 44 items, whose validity was decided by content validity method. The data was analyzed in SPSS (version 16. Findings: The results showed that in terms of “online resources”, “library collection,” and “navigation”, there is a significant relationship between the digital library' user interface design in both types of countries. Results: The items of “online public access catalogue (OPAC” and “visits statistics” were observed in more developing countries’ digital libraries' websites. However, the item of “menu and submenus to introduce library' sections” was presented in more developed countries’ digital libraries' websites. Moreover, by analyzing the number of items in the selected websites, “American Memory” with 44 items, “International Children Digital Library” with 40 items, and “California” with 39 items were the best, and “Berkeley Sun Site” with 10 items was the worst website. Despite more and better quality digital libraries in developed countries, the quality of digital libraries websites in developing countries is considerable. In general, some of the newly established

  16. Using Content Analysis To Evaluate The Impact of Technological Development In Instructional Materials

    Directory of Open Access Journals (Sweden)

    G.P. Keiler

    2014-08-01

    Full Text Available Textbooks are widely used as a teaching tool, and are considered very important in severaleducational environments, from elementary to tertiary education levels. Since the firsttextbook arose in the seventeenth century, printed books are the most popular format oftextbooks published. New technologies developed over years such as paper, ink andprinting hardware. These have made it possible to present printed books in even moreattractive formats. Moreover, digital technologies allowed textbooks to providecomplementary content, such as software, audio and video. Aiming to understand hownew technologies has impacted both textbook presentation and content, we run anexternal representations (ER content analysis in a textbook chapter and on aneducational software (eBook, both about muscle contraction. The three editions ofBioquímica Básica textbook (1990, 1999 and 2007, written by Anita Marzzoco andBayardo B. Torres and the four versions of Contração Muscular software developed byEduardo Galembeck et al. were analyzed. The obtained results showed that the textbookhad changes in relation to typography (paper size, kind of paper and colors of printing,and to ERs presented (use of electronic micrograph and 3D models in the 3rd edition andthe exclusion of some images and graphs previously used. Regarding the ContraçãoMuscular software, there were several changes in relation to the visual aspect, such asimages and icons, and also code updates to make the software compatible with newtechnologies developed since the first version was released. Although technology hasdriven some updates in both cases, this happened in different aspects includingpossibilities to create a modern layout and cheaper printer services, in the case of thetextbook, and graphic design and software usability, in the case of the eBook. Thuschanging the way information is presented to the users.

  17. Designing electronic module based on learning content development system in fostering students’ multi representation skills

    Science.gov (United States)

    Resita, I.; Ertikanto, C.

    2018-05-01

    This study aims to develop electronic module design based on Learning Content Development System (LCDS) to foster students’ multi representation skills in physics subject material. This study uses research and development method to the product design. This study involves 90 students and 6 physics teachers who were randomly chosen from 3 different Senior High Schools in Lampung Province. The data were collected by using questionnaires and analyzed by using quantitative descriptive method. Based on the data, 95% of the students only use one form of representation in solving physics problems. Representation which is tend to be used by students is symbolic representation. Students are considered to understand the concept of physics if they are able to change from one form to the other forms of representation. Product design of LCDS-based electronic module presents text, image, symbolic, video, and animation representation.

  18. Effects of helium content of microstructural development in Type 316 stainless steel under neutron irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Maziasz, P.J.

    1985-11-01

    This work investigated the sensitivity of microstructural evolution, particularly precipitate development, to increased helium content during thermal aging and during neutron irradiation. Helium (110 at. ppM) was cold preinjected into solution annealed (SA) DO-heat type 316 stainess steel (316) via cyclotron irradiation. These specimens were then exposed side by side with uninjected samples. Continuous helium generation was increased considerably relative to EBR-II irradiation by irradiation in HFIR. Data were obtained from quantitative analytical electron microscopy (AEM) in thin foils and on extraction replicas. 480 refs., 86 figs., 19 tabs.

  19. Effects of helium content of microstructural development in Type 316 stainless steel under neutron irradiation

    International Nuclear Information System (INIS)

    Maziasz, P.J.

    1985-11-01

    This work investigated the sensitivity of microstructural evolution, particularly precipitate development, to increased helium content during thermal aging and during neutron irradiation. Helium (110 at. ppM) was cold preinjected into solution annealed (SA) DO-heat type 316 stainess steel (316) via cyclotron irradiation. These specimens were then exposed side by side with uninjected samples. Continuous helium generation was increased considerably relative to EBR-II irradiation by irradiation in HFIR. Data were obtained from quantitative analytical electron microscopy (AEM) in thin foils and on extraction replicas. 480 refs., 86 figs., 19 tabs

  20. Characterization of Sugar Contents and Sucrose Metabolizing Enzymes in Developing Leaves of Hevea brasiliensis

    Directory of Open Access Journals (Sweden)

    Jinheng Zhu

    2018-02-01

    Full Text Available Sucrose-metabolizing enzymes in plant leaves have hitherto been investigated mainly in temperate plants, and rarely conducted in tandem with gene expression and sugar analysis. Here, we investigated the sugar content, gene expression, and the activity of sucrose-metabolizing enzymes in the leaves of Hevea brasiliensis, a tropical tree widely cultivated for natural rubber. Sucrose, fructose and glucose were the major sugars detected in Hevea leaves at four developmental stages (I to IV, with starch and quebrachitol as minor saccharides. Fructose and glucose contents increased until stage III, but decreased strongly at stage IV (mature leaves. On the other hand, sucrose increased continuously throughout leaf development. Activities of all sucrose-cleaving enzymes decreased markedly at maturation, consistent with transcript decline for most of their encoding genes. Activity of sucrose phosphate synthase (SPS was low in spite of its high transcript levels at maturation. Hence, the high sucrose content in mature leaves was not due to increased sucrose-synthesizing activity, but more to the decline in sucrose cleavage. Gene expression and activities of sucrose-metabolizing enzymes in Hevea leaves showed striking differences compared with other plants. Unlike in most other species where vacuolar invertase predominates in sucrose cleavage in developing leaves, cytoplasmic invertase and sucrose synthase (cleavage direction also featured prominently in Hevea. Whereas SPS is normally responsible for sucrose synthesis in plant leaves, sucrose synthase (synthesis direction was comparable or higher than that of SPS in Hevea leaves. Mature Hevea leaves had an unusually high sucrose:starch ratio of about 11, the highest reported to date in plants.

  1. Content Validity and Acceptability of a Developed Worktext in Basic Mathematics 2

    Directory of Open Access Journals (Sweden)

    Mae Joy F. Tan-Espinar

    2017-02-01

    Full Text Available Teaching tertiary mathematics entails the use of instructional materials which lead to independent learning. The study evaluated the content validity and level of acceptability of a developed worktext in Basic Mathematics 2. It also found the significant difference between the respondents’ evaluation. Likewise, the study found the significant difference in the pretest and posttest performance between experimental and the control group and the difference between the posttest of the experimental and control groups. The study utilized the descriptive comparative method in determining the validity and acceptability of the developed worktext and the difference between the evaluation of experts/teachers and the student respondents. Quasi-experimental design was also used to find out if the worktext is effective in teaching the course employing t-test for correlated samples and t-test for independent samples. The result showed that the content validity and acceptability is very much valid and very much acceptable. The difference in the post-test between the experimental and the control groups was significant. It is concluded that the worktext is effective to be used in teaching the course.

  2. A content analysis of posthumous sperm procurement protocols with considerations for developing an institutional policy.

    Science.gov (United States)

    Bahm, Sarah M; Karkazis, Katrina; Magnus, David

    2013-09-01

    To identify and analyze existing posthumous sperm procurement (PSP) protocols in order to outline central themes for institutions to consider when developing future policies. Qualitative content analysis. Large academic institutions across the United States. We performed a literature search and contacted 40 institutions to obtain nine full PSP protocols. We then performed a content analysis on these policies to identify major themes and factors to consider when developing a PSP protocol. Presence of a PSP policy. We identified six components of a thorough PSP protocol: Standard of Evidence, Terms of Eligibility, Sperm Designee, Restrictions on Use in Reproduction, Logistics, and Contraindications. We also identified two different approaches to policy structure. In the Limited Role approach, institutions have stricter consent requirements and limit their involvement to the time of procurement. In the Family-Centered approach, substituted judgment is permitted but a mandatory wait period is enforced before sperm use in reproduction. Institutions seeking to implement a PSP protocol will benefit from considering the six major building blocks of a thorough protocol and where they would like to fall on the spectrum from a Limited Role to a Family-Centered approach. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Development of a golf-specific load monitoring tool: Content validity and feasibility.

    Science.gov (United States)

    Williams, Scott B; Gastin, Paul B; Saw, Anna E; Robertson, Sam

    2018-05-01

    Athletes often record details of their training and competitions, supported by information such as environmental conditions, travel, as well as how they felt. However, it is not known how prevalent these practices are in golfers, or how valuable this process is perceived. The purpose of this study was to develop a golf-specific load monitoring tool (GLMT), and establish the content validity and feasibility of this tool amongst high-level golfers. In the first phase of development, 21 experts were surveyed to determine the suitability of items for inclusion in the GLMT. Of the 36 items, 21 received >78% agreement, a requirement to establish content validity and for inclusion in the GLMT. Total duration was the preferred metric for golf-specific activities, whilst rating of perceived exertion (RPE) was preferred for measuring physical training. In the second phase, feasibility of the tool was assessed by surveying 13 high-level male golfers following 28-days of daily GLMT use. All items included in the GLMT were deemed feasible to record, with all players participating in the feasibility study providing high to very high ratings. Golfers responded that they would consider using a load monitoring tool of this nature long term, provided it can be completed in less than five minutes per day.

  4. Processes and content of narrative identity development in adolescence: gender and well-being.

    Science.gov (United States)

    McLean, Kate C; Breen, Andrea V

    2009-05-01

    The present study examined narrative identity in adolescence (14-18 years) in terms of narrative content and processes of identity development. Age- and gender-related differences in narrative patterns in turning point memories and gender differences in the content and functions for sharing those memories were examined, as was the relationship between narrative patterns and self-esteem. The narrative patterns focused on were meaning-making (learning from past events) and emotionality of the narratives, specified as overall positive emotional tone and redemptive sequencing. Results showed an age-related increase in meaning-making but no gender differences in the degree of meaning-making. Results further showed that gender predicted self-esteem and that boys evidenced higher self-esteem. Emotionality also predicted self-esteem; this was especially true for redemption and for boys. In terms of telling functions, girls endorsed more relational reasons for telling memories than did boys. Results are discussed in terms of potential gendered and nongendered pathways for identity development in adolescence. Copyright 2009 APA, all rights reserved

  5. Influence of copper content on microstructure development of AlSi9Cu3 alloy

    Directory of Open Access Journals (Sweden)

    Brodarac Zovko Z.

    2014-01-01

    Full Text Available Microstructure development and possible interaction of present elements have been determined in charge material of EN AlSi9Cu3 quality. Literature review enables prediction of solidification sequence. Modelling of equilibrium phase diagram for examined chemical composition has been performed, which enables determination of equilibrium solidification sequence. Microstructural investigation indicated distribution and morphology of particular phase. Metallographic analysis tools enable exact determination of microstructural constituents: matrix αAl, eutectic αAl+βSi, iron base intermetallic phase - Al5FeSi, Alx(Fe,MnyCuuSiw and/or Alx(Fe,MnyMgzCuuSiw and copper base phases in ternary eutectic morphology Al-Al2Cu-Si and in complex intermetallic ramified morphology Alx(Fe,MnyMgzSiuCuw. Microstructure development examination reveals potential differences due to copper content which is prerequisite for high values of final mechanical, physical and technological properties of cast products.

  6. Mutational breeding and genetic engineering in the development of high grain protein content.

    Science.gov (United States)

    Wenefrida, Ida; Utomo, Herry S; Linscombe, Steve D

    2013-12-04

    Cereals are the most important crops in the world for both human consumption and animal feed. Improving their nutritional values, such as high protein content, will have significant implications, from establishing healthy lifestyles to helping remediate malnutrition problems worldwide. Besides providing a source of carbohydrate, grain is also a natural source of dietary fiber, vitamins, minerals, specific oils, and other disease-fighting phytocompounds. Even though cereal grains contain relatively little protein compared to legume seeds, they provide protein for the nutrition of humans and livestock that is about 3 times that of legumes. Most cereal seeds lack a few essential amino acids; therefore, they have imbalanced amino acid profiles. Lysine (Lys), threonine (Thr), methionine (Met), and tryptophan (Trp) are among the most critical and are a limiting factor in many grain crops for human nutrition. Tremendous research has been put into the efforts to improve these essential amino acids. Development of high protein content can be outlined in four different approaches through manipulating seed protein bodies, modulating certain biosynthetic pathways to overproduce essential and limiting amino acids, increasing nitrogen relocation to the grain through the introduction of transgenes, and exploiting new genetic variance. Various technologies have been employed to improve protein content including conventional and mutational breeding, genetic engineering, marker-assisted selection, and genomic analysis. Each approach involves a combination of these technologies. Advancements in nutrigenomics and nutrigenetics continue to improve public knowledge at a rapid pace on the importance of specific aspects of food nutrition for optimum fitness and health. An understanding of the molecular basis for human health and genetic predisposition to certain diseases through human genomes enables individuals to personalize their nutritional requirements. It is critically important

  7. Informing Estimates of Program Effects for Studies of Mathematics Professional Development Using Teacher Content Knowledge Outcomes.

    Science.gov (United States)

    Phelps, Geoffrey; Kelcey, Benjamin; Jones, Nathan; Liu, Shuangshuang

    2016-10-03

    Mathematics professional development is widely offered, typically with the goal of improving teachers' content knowledge, the quality of teaching, and ultimately students' achievement. Recently, new assessments focused on mathematical knowledge for teaching (MKT) have been developed to assist in the evaluation and improvement of mathematics professional development. This study presents empirical estimates of average program change in MKT and its variation with the goal of supporting the design of experimental trials that are adequately powered to detect a specified program effect. The study drew on a large database representing five different assessments of MKT and collectively 326 professional development programs and 9,365 teachers. Results from cross-classified hierarchical growth models found that standardized average change estimates across the five assessments ranged from a low of 0.16 standard deviations (SDs) to a high of 0.26 SDs. Power analyses using the estimated pre- and posttest change estimates indicated that hundreds of teachers are needed to detect changes in knowledge at the lower end of the distribution. Even studies powered to detect effects at the higher end of the distribution will require substantial resources to conduct rigorous experimental trials. Empirical benchmarks that describe average program change and its variation provide a useful preliminary resource for interpreting the relative magnitude of effect sizes associated with professional development programs and for designing adequately powered trials. © The Author(s) 2016.

  8. Use of Content Based Instruction and Socratic Discussion for ESL Undergraduate Biomedical Science Students to Develop Critical Thinking Skills

    Science.gov (United States)

    Burder, Ronan L.; Tangalaki, Kathy; Hryciw, Deanne H.

    2014-01-01

    Content based language instruction can assist English as a second language (ESL) students to achieve better learning and teaching outcomes, however, it is primarily used to understand content, and may not help to develop critical analysis skills. Here we describe a pilot study that used a "Socratic" small-group discussion in addition to…

  9. Developing Content Knowledge in Struggling Readers: Differential Effects of Strategy Instruction for Younger and Older Elementary Students

    Science.gov (United States)

    Elleman, Amy M.; Olinghouse, Natalie G.; Gilbert, Jennifer K.; Spencer, Jane Lawrence; Compton, Donald L.

    2017-01-01

    This study compared the effects of 2 strategy-based comprehension treatments intended to promote vocabulary and content knowledge for elementary students at risk for developing reading difficulties (N = 105) with a traditional content approach. The study examined the effectiveness of strategy versus nonstrategy instruction on reading…

  10. Determining the water-cement ratio, cement content, water content and degree of hydration of hardened cement paste: Method development and validation on paste samples

    International Nuclear Information System (INIS)

    Wong, H.S.; Buenfeld, N.R.

    2009-01-01

    We propose a new method to estimate the initial cement content, water content and free water/cement ratio (w/c) of hardened cement-based materials made with Portland cements that have unknown mixture proportions and degree of hydration. This method first quantifies the composition of the hardened cement paste, i.e. the volumetric fractions of capillary pores, hydration products and unreacted cement, using high-resolution field emission scanning electron microscopy (FE-SEM) in the backscattered electron (BSE) mode and image analysis. From the obtained data and the volumetric increase of solids during cement hydration, we compute the initial free water content and cement content, hence the free w/c ratio. The same method can also be used to calculate the degree of hydration. The proposed method has the advantage that it is quantitative and does not require comparison with calibration graphs or reference samples made with the same materials and cured to the same degree of hydration as the tested sample. This paper reports the development, assumptions and limitations of the proposed method, and preliminary results from Portland cement pastes with a range of w/c ratios (0.25-0.50) and curing ages (3-90 days). We also discuss the extension of the technique to mortars and concretes, and samples made with blended cements.

  11. The Role of Fine Sediment Content on Soil Consolidation and Debris Flows Development after Earthquake

    Science.gov (United States)

    Lyu, L.; Xu, M., III; Wang, Z.

    2017-12-01

    Fine sediment has been identified as an important factor determining the critical runoff that initiates debris flows because its contribution to shear strength through consolidation. Especially, owing to the 2008 Wenchuan earthquake in China enormous of loose sediment with different fractions of fine particles was eroded and supplied as materials for debris flows. The loose materials are gradually consolidated along with time, and therefore stronger rainfall is required to overcome the shear strength and to initiate debris flows. In this study, flume experiments were performed to explore soil consolidation and shear strength on mass failure and debris flow initiation under the conditions that different fractions of fine sediment were contained in the materials. Under the low content of fine sediment conditions (mass percentages: 0-10%), the debris flows formed with large pores and low shear strength and thus fine particles were too few to fill up the pores among the coarse particles. The consolidation rate was mostly influenced by the content of the fine particles. Consolidation of fine particles caused an increase of the shear strength and decrease of the rainfall infiltration, and therefore, debris flow initiation required stronger rainfall as the consolidation of the fine particles developed.

  12. Assessing STEM content learning: using the Arctic's changing climate to develop 21st century learner

    Science.gov (United States)

    Henderson, G. R.; Durkin, S.; Moran, A.

    2016-12-01

    In recent years the U.S. federal government has called for an increased focus on science, technology, engineering, and mathematics (STEM) in the educational system to ensure that there will be sufficient technical expertise to meet the needs of business and industry. As a direct result of this STEM emphasis, the number of outreach activities aimed at actively engaging these students in STEM learning has surged. Such activities, frequently in the form of summer camps led by university faculty, have targeted primary and secondary school students with the goal of growing student interest in STEM majors and STEM careers. This study assesses short-term content learning using a climate module that highlights rapidly changing Arctic climate conditions to illustrate concepts of radiative energy balance and climate feedback. Hands-on measurement of short and longwave radiation using simple instrumentation is used to demonstrate concepts that are then related back to the "big picture" Arctic issue. Pre and post module questionnaires were used to assess content learning, as this learning type has been identified as the basis for STEM literacy and the vehicle by which 21st century learning skills are usually developed. In this instance, students applied subject knowledge they gained by taking radiation measurements to better understand the real-world problem of climate change.

  13. Expansion of Biology Teachers' Pedagogical Content Knowledge (PCK) During a Long-Term Professional Development Program

    Science.gov (United States)

    Rozenszajn, Ronit; Yarden, Anat

    2014-02-01

    Experienced teachers possess a unique teaching knowledge comprised of an inter-related set of knowledge and beliefs that gives direction and justification to a teacher's actions. This study examined the expansion of two components of pedagogical content knowledge (PCK) of three in-service teachers in the course of a professional development program aimed at designing new teaching and learning materials suggested by the teachers themselves. The research presents an enlargement of previous PCK representations by focusing on a detailed representation of two main PCK domains: teaching and learning, including ten PCK components that emerged in the course of data analysis. This representation enabled revealing the unique PCK held by each teacher and to characterize the expansion of the two components of the participating teachers' PCK during the long-term professional development program. Retention of major parts of the expanded PCK a year after termination of the program implies that designing and implementing new teaching and learning materials based on the teachers' experiences, needs, and knowledge in a workshop format accompanied by biology and science education courses might provide a powerful means for PCK expansion. We recommend that designers of professional development programs be aware of the unique PCK held by each teacher in order to promote meaningful professional development of each teacher. Moreover, the PCK representations that were identified in the course of this study enabled clarifying the "orientation toward teaching science" category of PCK which appears to be unclear in current literature.

  14. Educative Mentoring: How a Mentor Supported a Preservice Biology Teacher's Pedagogical Content Knowledge Development

    Science.gov (United States)

    Barnett, Ellen; Friedrichsen, Patricia J.

    2015-11-01

    Research suggests discipline-specific, educative mentoring can help preservice teachers develop more sophisticated pedagogical content knowledge (PCK). However, there are few studies examining the nature of mentors' practice and how mentors influence preservice teacher's (PST) PCK. The purpose of this case study was to describe the strategies used by a secondary biology mentor teacher to support the development of a PST's PCK. The primary data sources were the transcripts of audio-recorded, daily meetings between the mentor and the PST during two curriculum units: DNA/Protein Synthesis and Evolution. The mentor influenced the PST's teaching orientation by repeatedly comparing teacher- and student-centered approaches, asking him to consider how students learn, and asking him to self-assess whether his instruction aligned with his teaching beliefs. The mentor helped the PST develop topic-specific knowledge of instructional strategies by sharing strategies she used previously, modeling critical reflection, and inviting him to critically reflect on his own instructional strategies. Topic-specific knowledge of students' understanding of science was developed by discussing common student misconceptions revealed in students' conversations and by sharing the results of test-item analysis from previous unit tests. The mentor helped develop the PST's topic-specific knowledge of assessment by helping him critically analyze and revise previous examinations to better align with the current curriculum units. Topic-specific knowledge of curricula was developed by jointly grappling with decisions about concept sequencing within units. The study includes implications for research, science teacher education, and professional development for mentors.

  15. Developing a model of pedagogical content knowledge for secondary and post-secondary mathematics instruction

    Directory of Open Access Journals (Sweden)

    Shandy Hauk

    2014-07-01

    Full Text Available The accepted framing of mathematics pedagogical content knowledge (PCK as part of mathematical knowledge for teaching has centered on the question: What mathematical reasoning, insight, understanding, and skills are required for a person to teach elementary mathematics? Many have worked to address this question in K-8 teaching. Yet, there remains a call for examples and theory in the context of teachers with greater mathematical preparation and older students with varied and complex experiences in learning mathematics. In this theory development report we offer background and examples for an extended model of PCK – as the interplay among conceptually-rich mathematical understandings, experience in and of teaching, and multiple culturally-mediated classroom interactions.

  16. Content and quality of workplace guidelines developed to prevent mental health problems

    DEFF Research Database (Denmark)

    Nexø, Mette Andersen; Kristensen, Josefine Vejlby; Grønvad, Majbritt Thorhauge

    2018-01-01

    Objectives A wide range of guidelines have been developed to prevent work-related mental health problems (MHP), but little is known about the quality of such guidelines. We systematically reviewed the content and quality of workplace guidelines aiming to prevent, detect, and/or manage work......-related MHP. Methods We conducted systematic online and database searches (MEDLINE; Web of Science; PsychNET; occupational safety and health databases) to identify guidelines. Eligibility criteria included guidelines recommending primary, secondary, or tertiary preventive interventions to be implemented...... at the workplace by employers, employees or organizational staff. A minimum of minimum three independent reviewers assessed the quality of guidelines using the Guidelines for Research and Evaluation (AGREE II). Guidelines rated ≥65% with regards to domain I, II, and III were considered to be of good developmental...

  17. Development of clinical contents model markup language for electronic health records.

    Science.gov (United States)

    Yun, Ji-Hyun; Ahn, Sun-Ju; Kim, Yoon

    2012-09-01

    To develop dedicated markup language for clinical contents models (CCM) to facilitate the active use of CCM in electronic health record systems. Based on analysis of the structure and characteristics of CCM in the clinical domain, we designed extensible markup language (XML) based CCM markup language (CCML) schema manually. CCML faithfully reflects CCM in both the syntactic and semantic aspects. As this language is based on XML, it can be expressed and processed in computer systems and can be used in a technology-neutral way. CCML HAS THE FOLLOWING STRENGTHS: it is machine-readable and highly human-readable, it does not require a dedicated parser, and it can be applied for existing electronic health record systems.

  18. Relationship between mathematics teacher subject matter knowledge, pedagogical content knowledge and professional development needs

    Science.gov (United States)

    Tajudin, Nor'ain Mohd; Chinnappan, Mohan; Saad, Noor Shah

    2017-05-01

    Two key variables emerged from the literature review is that Specific Matter Knowledge [SMK] and Pedagogical Content Knowledge [PCK] can influence the mathematics teachers' Professional Development [PD] needs. However, the key variables of SMK and PCK that were being investigated were not defined clearly. Empirical evidence that support relationship between SMK and PD and PCK and PD were not verified. In addition, how does PCK mediate SMK and PD is not clear and somewhat lacking. Therefore, the purpose of this paper was to examine the relationship between primary mathematics teacher's SMK, PCK and PD needs. Results of path analysis with SmartPLS indicated that the direct effect of SMK on PD was mediated via PCK. This data provide support for the claim that PD programs for future teachers of primary mathematics should be driven by a more nuanced understanding of the link between SMK and PCK.

  19. Framing student dialogue and argumentation: Content knowledge development and procedural knowing in SSI inquiry group work

    Directory of Open Access Journals (Sweden)

    Anne Kristine Byhring

    2014-10-01

    Full Text Available In this article, we discuss the negotiation of the situated common ground in classroom conversations. Decision making on socioscientific issues (SSI includes norms of diverse funds of knowledge and interests. Arguments and justification may include warrants that cannot necessarily be weighed on the same scale. We discuss Roberts’ Visions 1 and 2 of scientific literacy as framing the common ground of classroom discussions. Two teacher–student dialogue sequences with 11th grade students from the Norwegian research project ElevForsk exemplify the negotiation of the situated common ground and the students’ deliberations. Our analysis examines what goes on in the thematic content, as well as at the interpersonal level of language use. Further, we suggest that different framings may complement each other and provide a space for the students’ emerging scientific conceptual development as well as for deliberation as a form of emerging procedural knowing.

  20. Development and Application of High-Content Biological Screening for Modulators of NET Production

    Directory of Open Access Journals (Sweden)

    Ilaria J. Chicca

    2018-03-01

    Full Text Available Neutrophil extracellular traps (NETs are DNA-based antimicrobial web-like structures whose release is predominantly mediated by reactive oxygen species (ROS; their purpose is to combat infections. However, unbalanced NET production and clearance is involved in tissue injury, circulation of auto-antibodies and development of several chronic diseases. Currently, there is lack of agreement regarding the high-throughput methods available for NET investigation. This study, therefore, aimed to develop and optimize a high-content analysis (HCA approach, which can be applied for the assay of NET production and for the screening of compounds involved in the modulation of NET release. A suitable paraformaldehyde fixation protocol was established to enable HCA of neutrophils and NETs. Bespoke and in-built bioinformatics algorithms were validated by comparison with standard low-throughput approaches for application in HCA of NETs. Subsequently, the optimized protocol was applied to high-content screening (HCS of a pharmaceutically derived compound library to identify modulators of NETosis. Of 56 compounds assessed, 8 were identified from HCS for further characterization of their effects on NET formation as being either inducers, inhibitors or biphasic modulators. The effects of these compounds on naïve neutrophils were evaluated by using specific assays for the induction of ROS and NET production, while their modulatory activity was validated in phorbol 12-myristate 13-acetate-stimulated neutrophils. Results indicated the involvement of glutathione reductase, Src family kinases, molecular-target-of-Rapamycin, and mitogen-activated-protein-kinase pathways in NET release. The compounds and pathways identified may provide targets for novel therapeutic approaches for treating NET-associated pathologies.

  1. The Use of Lesson Study Combined with Content Representation in the Planning of Physics Lessons During Field Practice to Develop Pedagogical Content Knowledge

    Science.gov (United States)

    Juhler, Martin Vogt

    2016-08-01

    Recent research, both internationally and in Norway, has clearly expressed concerns about missing connections between subject-matter knowledge, pedagogical competence and real-life practice in schools. This study addresses this problem within the domain of field practice in teacher education, studying pre-service teachers' planning of a Physics lesson. Two means of intervention were introduced. The first was lesson study, which is a method for planning, carrying out and reflecting on a research lesson in detail with a learner and content-centered focus. This was used in combination with a second means, content representations, which is a systematic tool that connects overall teaching aims with pedagogical prompts. Changes in teaching were assessed through the construct of pedagogical content knowledge (PCK). A deductive coding analysis was carried out for this purpose. Transcripts of pre-service teachers' planning of a Physics lesson were coded into four main PCK categories, which were thereafter divided into 16 PCK sub-categories. The results showed that the intervention affected the pre-service teachers' potential to start developing PCK. First, they focused much more on categories concerning the learners. Second, they focused far more uniformly in all of the four main categories comprising PCK. Consequently, these differences could affect their potential to start developing PCK.

  2. Development and content validation of the information assessment method for patients and consumers.

    Science.gov (United States)

    Pluye, Pierre; Granikov, Vera; Bartlett, Gillian; Grad, Roland M; Tang, David L; Johnson-Lafleur, Janique; Shulha, Michael; Barbosa Galvão, Maria Cristiane; Ricarte, Ivan Lm; Stephenson, Randolph; Shohet, Linda; Hutsul, Jo-Anne; Repchinsky, Carol A; Rosenberg, Ellen; Burnand, Bernard; Légaré, France; Dunikowski, Lynn; Murray, Susan; Boruff, Jill; Frati, Francesca; Kloda, Lorie; Macaulay, Ann; Lagarde, François; Doray, Geneviève

    2014-02-18

    Online consumer health information addresses health problems, self-care, disease prevention, and health care services and is intended for the general public. Using this information, people can improve their knowledge, participation in health decision-making, and health. However, there are no comprehensive instruments to evaluate the value of health information from a consumer perspective. We collaborated with information providers to develop and validate the Information Assessment Method for all (IAM4all) that can be used to collect feedback from information consumers (including patients), and to enable a two-way knowledge translation between information providers and consumers. Content validation steps were followed to develop the IAM4all questionnaire. The first version was based on a theoretical framework from information science, a critical literature review and prior work. Then, 16 laypersons were interviewed on their experience with online health information and specifically their impression of the IAM4all questionnaire. Based on the summaries and interpretations of interviews, questionnaire items were revised, added, and excluded, thus creating the second version of the questionnaire. Subsequently, a panel of 12 information specialists and 8 health researchers participated in an online survey to rate each questionnaire item for relevance, clarity, representativeness, and specificity. The result of this expert panel contributed to the third, current, version of the questionnaire. The current version of the IAM4all questionnaire is structured by four levels of outcomes of information seeking/receiving: situational relevance, cognitive impact, information use, and health benefits. Following the interviews and the expert panel survey, 9 questionnaire items were confirmed as relevant, clear, representative, and specific. To improve readability and accessibility for users with a lower level of literacy, 19 items were reworded and all inconsistencies in using a

  3. The Pediatrics Milestones Assessment Pilot: Development of Workplace-Based Assessment Content, Instruments, and Processes.

    Science.gov (United States)

    Hicks, Patricia J; Margolis, Melissa; Poynter, Sue E; Chaffinch, Christa; Tenney-Soeiro, Rebecca; Turner, Teri L; Waggoner-Fountain, Linda; Lockridge, Robin; Clyman, Stephen G; Schwartz, Alan

    2016-05-01

    To report on the development of content and user feedback regarding the assessment process and utility of the workplace-based assessment instruments of the Pediatrics Milestones Assessment Pilot (PMAP). One multisource feedback instrument and two structured clinical observation instruments were developed and refined by experts in pediatrics and assessment to provide evidence for nine competencies based on the Pediatrics Milestones (PMs) and chosen to inform residency program faculty decisions about learners' readiness to serve as pediatric interns in the inpatient setting. During the 2012-2013 PMAP study, 18 U.S. pediatric residency programs enrolled interns and subinterns. Faculty, residents, nurses, and other observers used the instruments to assess learner performance through direct observation during a one-month rotation. At the end of the rotation, data were aggregated for each learner, milestone levels were assigned using a milestone classification form, and feedback was provided to learners. Learners and site leads were surveyed and/or interviewed about their experience as participants. Across the sites, 2,338 instruments assessing 239 learners were completed by 630 unique observers. Regarding end-of-rotation feedback, 93% of learners (128/137) agreed the assessments and feedback "helped me understand how those with whom I work perceive my performance," and 85% (117/137) agreed they were "useful for constructing future goals or identifying a developmental path." Site leads identified several benefits and challenges to the assessment process. PM-based instruments used in workplace-based assessment provide a meaningful and acceptable approach to collecting evidence of learner competency development. Learners valued feedback provided by PM-based assessment.

  4. Developing the content of a locomotor disability scale for adults in Bangladesh: a qualitative study.

    Science.gov (United States)

    Mahmud, Ilias; Clarke, Lynda; Ploubidis, George B

    2017-01-01

    Bangladesh has an estimated 17 million adults with disabilities. A significant proportion of them are believed to have locomotor disabilities. There are over 300 non-governmental organizations providing different types of rehabilitation services to them. However, there is no locally developed and validated locomotor disability measurement scale in Bangladesh. The purpose of this study was to develop a locomotor disability scale with disability indicators suitable for adults in Bangladesh. Semi-structured interviews were conducted with 25 purposively selected adults with locomotor disabilities to generate scale items. At the second stage, cognitive interviews were conducted with 12 purposively selected adults with locomotor disabilities in order to refine the measurement questions and response categories. Data were analysed using the framework technique- identifying, abstracting, charting and matching themes across the interviews. For a locomotor disability scale, 70 activities (disability indicators) were identified: 37 mobility activities, 9 activities of daily living, 17 work/productivity activities and 7 leisure activities. Cognitive interviews revealed that when asking the respondents to rate their difficulty in performing the activities, instead of just mentioning the activity name, such as taking a bath or shower, a detailed description of the activity and response options were necessary to ensure consistent interpretation of the disability indicators and response options across all respondents. Identifying suitable disability indicators was the first step in developing a locomotor disability scale for adults in Bangladesh. Interviewing adults with locomotor disabilities in Bangladesh ensured that the locomotor disability scale is of relevance to them and consequently it has excellent content validity. Further research is needed to evaluate the psychometric properties of this scale.

  5. Technological Pedagogical Content Knowledge (TPACK): The Development and Validation of an Assessment Instrument for Preservice Teachers

    Science.gov (United States)

    Schmidt, Denise A.; Baran, Evrim; Thompson, Ann D.; Mishra, Punya; Koehler, Matthew J.; Shin, Tae S.

    2009-01-01

    Based in Shulman's idea of Pedagogical Content Knowledge, Technological Pedagogical Content Knowledge (TPACK) has emerged as a useful frame for describing and understanding the goals for technology use in preservice teacher education. This paper addresses the need for a survey instrument designed to assess TPACK for preservice teachers. The paper…

  6. Developing Mathematical Content Knowledge for Teaching: One Preservice Teacher and Her Planning

    Science.gov (United States)

    Wilson, Susanna

    2016-01-01

    This paper describes how a new pre-service teacher engaged with mathematical content in order to learn it for teaching, during practicum. The results show that the PST learned mathematical content by initiating and carrying out a preparation phase prior to planning. This phase involved searching through internet sites and making notes that were…

  7. LOW CONTENT OF RADIONUCLIDES IN NATURAL ENVIRONMENT AND PRODUCTION AS A RATIONALE FOR DEVELOPMENT OF RECREATIONAL POTENTIAL OF NORTHERN BUKOVINA

    Directory of Open Access Journals (Sweden)

    Natalia OMEL’CHENKO

    2017-06-01

    Full Text Available Investigation on food products contamination by Cesium-137 and Strontium-90, detection of content of natural radionuclides (Radium-226, Thorium-232, Potassium-40 in raw materials and finished products of building industry, monitoring of some radionuclides content in soils of mountainous area of Northern Bukovina was carried out. All the results were analyzed and discussed in view of the life safety position. Data on radionuclides content in surrounding natural environment as well as in building and food industry production confirm Northern Bukovina territory’s attractiveness and safety for recreation areas development.

  8. Sitting with the scientists: a collaborative approach to STEM content development

    Science.gov (United States)

    Mattson, Barbara

    2018-01-01

    For over two decades, the Goddard Astrophysics Education Team has been an integrated part of NASA Goddard’s Astrophysics Science Division. As part of NASA’s largest astrophysics organization, our team is in a unique position to collaborate with the division’s scientists, engineers, and technical personnel - our subject matter experts (SMEs) - in a variety of capacities. We often seek input from our SMEs to help implement our education programs - to ensure our programs’ scientific accuracy, to help us employ cutting-edge topics, and to promote authentic science processes. At the same time, we act as education experts for our SMEs to help them implement their ideas. We see this as a true partnership, with many opportunities for SME participation. Our current STEM Activation programs, Afterschool Universe and NASA Family Science Night, were created with strong involvement from division scientists, and our latest sessions on galaxies were developed in collaboration with an active researcher. In addition to our own programming, we have been tasked with providing NASA astrophysics content and expertise to the Goddard Office of Education, the Heliophysics Education Consortium (and their cross-division efforts), and the NASA Science Mission Directorate STEM Activation Community. This talk will provide an overview of our team’s current efforts and the ways in which we partner with our division’s SMEs.

  9. Development and Nature of Preservice Chemistry Teachers' Pedagogical Content Knowledge for Nature of Science

    Science.gov (United States)

    Demirdöğen, Betül; Hanuscin, Deborah L.; Uzuntiryaki-Kondakci, Esen; Köseoğlu, Fitnat

    2016-08-01

    The purpose of this case study is to delve into the complexities of the early development of preservice chemistry teachers' science teaching orientations, knowledge of learners, knowledge of instructional strategies, and knowledge of assessment during a two-semester intervention designed to enhance their pedagogical content knowledge (PCK) for teaching nature of science (NOS). Thirty preservice chemistry teachers enrolled in a Research in Science Education course participated in the study. Qualitative data sources included responses to an open-ended instrument, interviews, observations, and artifacts such as lesson plans and reflection papers. Through the in-depth analysis of explicit PCK and constant comparative method of analysis, we identified the influence of the intervention on participants' PCK for NOS. Analysis of data revealed four major themes related to the nature of preservice chemistry teachers' NOS teaching practices and their PCK for NOS: (1) prerequisite knowledge and beliefs are necessary to teach NOS, (2) there is a developmental progression of PCK for NOS from knowledge to application level, (3) teachers need some comfort in their NOS understanding to teach NOS, and (4) the higher integration of PCK components leads to successful NOS teaching practices. Implications for science teacher education and research are discussed.

  10. Development and phytochemical content analysis of bun incorporated with Kappaphycus Alvarezii seaweed powder

    Science.gov (United States)

    Sasue, Anita; Kasim, Zalifah Mohd

    2016-11-01

    Consumer awareness of the importance of functional foods has greatly grown in the past years. Functional foods with elevated levels of antioxidants are of high demand because of its associated health benefits. As bread is a common component in our daily diet, it may be convenient food to deliver antioxidants at a high concentration. The main approach of this study is to incorporate Kappaphycus alvarezii seaweed powder (SWP) and white flour in the bun formulation in order to develop seaweed bun with higher level of phytochemicals. The fresh Kappaphycus alvarezii seaweeds were washed, soaked in distilled water overnight, dried in a cabinet dryer at 40°C for 24 hours and ground into fine powder using universal miller. There were five different percentages of SWP incorporated into bun that were formulation A - control (0% SWP), B (3% SWP), C (6% SWP), D (9% SWP) and E (12% SWP). All the samples were undergone texture, total phenolic content and DPPH analysis. Seaweed concentration had most significant effect on phytochemical constituents of the bun with TPC (35.07 GAE, mg/100g) and DPPH activity (49.02%) maximized when 12% SWP was incorporated into the flour (P<0.05). The incorporation of the SWP also gives significant effects towards the texture of the bun where the bun becomes harder and denser as compared to the control.

  11. Employing WebGL to develop interactive stereoscopic 3D content for use in biomedical visualization

    Science.gov (United States)

    Johnston, Semay; Renambot, Luc; Sauter, Daniel

    2013-03-01

    Web Graphics Library (WebGL), the forthcoming web standard for rendering native 3D graphics in a browser, represents an important addition to the biomedical visualization toolset. It is projected to become a mainstream method of delivering 3D online content due to shrinking support for third-party plug-ins. Additionally, it provides a virtual reality (VR) experience to web users accommodated by the growing availability of stereoscopic displays (3D TV, desktop, and mobile). WebGL's value in biomedical visualization has been demonstrated by applications for interactive anatomical models, chemical and molecular visualization, and web-based volume rendering. However, a lack of instructional literature specific to the field prevents many from utilizing this technology. This project defines a WebGL design methodology for a target audience of biomedical artists with a basic understanding of web languages and 3D graphics. The methodology was informed by the development of an interactive web application depicting the anatomy and various pathologies of the human eye. The application supports several modes of stereoscopic displays for a better understanding of 3D anatomical structures.

  12. Development of water movement model as a module of moisture content simulation in static pile composting.

    Science.gov (United States)

    Seng, Bunrith; Kaneko, Hidehiro; Hirayama, Kimiaki; Katayama-Hirayama, Keiko

    2012-01-01

    This paper presents a mathematical model of vertical water movement and a performance evaluation of the model in static pile composting operated with neither air supply nor turning. The vertical moisture content (MC) model was developed with consideration of evaporation (internal and external evaporation), diffusion (liquid and vapour diffusion) and percolation, whereas additional water from substrate decomposition and irrigation was not taken into account. The evaporation term in the model was established on the basis of reference evaporation of the materials at known temperature, MC and relative humidity of the air. Diffusion of water vapour was estimated as functions of relative humidity and temperature, whereas diffusion of liquid water was empirically obtained from experiment by adopting Fick's law. Percolation was estimated by following Darcy's law. The model was applied to a column of composting wood chips with an initial MC of 60%. The simulation program was run for four weeks with calculation span of 1 s. The simulated results were in reasonably good agreement with the experimental results. Only a top layer (less than 20 cm) had a considerable MC reduction; the deeper layers were comparable to the initial MC, and the bottom layer was higher than the initial MC. This model is a useful tool to estimate the MC profile throughout the composting period, and could be incorporated into biodegradation kinetic simulation of composting.

  13. The Nursing Diagnosis Development of Unemployment Disorder: Content Validation With Nursing Experts.

    Science.gov (United States)

    Bocchino, Anna; Medialdea, María Jesús; Lepiani, Isabel; Mejías, Concepción; Dueñas, María

    2017-10-01

    This study aimed to validate the definition and define the characteristics and related factors of unemployment disorder, a proposed nursing diagnosis. Using Fehring's diagnostic content validity model, Spanish experts were asked to assess the adequacy of the label, defining the characteristics and other related factors. The content validity index was 0.8690. A total of 16 defining characteristics reached major criteria (>0.80). The present study supports the proposed development of a nursing diagnosis for the human response to unemployment. The results suggest that the inclusion of the "unemployment disorder" diagnostic NANDA-I taxonomy would allow nursing professionals to identify the disorder and its causes and manifestations, and therefore provide the information needed for planning more relevant interventions and results. Validación de la definición, características definitorias y factores relacionados de trastorno por desempleo, una propuesta de diagnóstico enfermero. METODOLOGÍA: Usando el modelo de validación de contenido de Fehring, se consensuó mediante expertos españoles la denominación de la etiqueta, las características definitorias y otros factores relacionados. El índice de validez de contenido global fue 0.8690. Un total de 16 características definitorias alcanzaron carácter crítico (>0.80). CONCLUSIÓN: El presente estudio apoya la propuesta de elaborar un diagnóstico de enfermería para la respuesta humana al desempleo. IMPLICACIONES PRÁCTICAS: Los resultados obtenidos sugieren que la inclusión en la taxonomía NANDA-I del diagnóstico "trastorno por desempleo" permitiría a los profesionales de enfermería identificar el problema, sus causas y manifestaciones, y por lo tanto ofrecerían la información necesaria para planificar las intervenciones y resultados más pertinentes. © 2016 NANDA International, Inc.

  14. Development of Prediction Model and Experimental Validation in Predicting the Curcumin Content of Turmeric (Curcuma longa L.).

    Science.gov (United States)

    Akbar, Abdul; Kuanar, Ananya; Joshi, Raj K; Sandeep, I S; Mohanty, Sujata; Naik, Pradeep K; Mishra, Antaryami; Nayak, Sanghamitra

    2016-01-01

    The drug yielding potential of turmeric ( Curcuma longa L.) is largely due to the presence of phyto-constituent 'curcumin.' Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influenced by environmental factors. Hence, a prediction model based on artificial neural network (ANN) was developed to map genome environment interaction basing on curcumin content, soli and climatic factors from different agroclimatic regions for prediction of maximum curcumin content at various sites to facilitate the selection of suitable region for commercial cultivation of turmeric. The ANN model was developed and tested using a data set of 119 generated by collecting samples from 8 different agroclimatic regions of Odisha. The curcumin content from these samples was measured that varied from 7.2% to 0.4%. The ANN model was trained with 11 parameters of soil and climatic factors as input and curcumin content as output. The results showed that feed-forward ANN model with 8 nodes (MLFN-8) was the most suitable one with R 2 value of 0.91. Sensitivity analysis revealed that minimum relative humidity, altitude, soil nitrogen content and soil pH had greater effect on curcumin content. This ANN model has shown proven efficiency for predicting and optimizing the curcumin content at a specific site.

  15. Development of prediction model and experimental validation in predicting the curcumin content of turmeric (Curcuma longa L.

    Directory of Open Access Journals (Sweden)

    Abdul Akbar

    2016-10-01

    Full Text Available The drug yielding potential of turmeric (Curcuma longa L. is largely due to the presence of phyto-constituent ‘curcumin’. Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influenced by environmental factors. Hence, a prediction model based on artificial neural network (ANN was developed to map genome environment interaction basing on curcumin content, soli and climatic factors from different agroclimatic regions for prediction of maximum curcumin content at various sites to facilitate the selection of suitable region for commercial cultivation of turmeric. The ANN model was developed and tested using a data set of 119 generated by collecting samples from 8 different agroclimatic regions of Odisha. The curcumin content from these samples was measured that varied from 7.2% to 0.4%. The ANN model was trained with 11 parameters of soil and climatic factors as input and curcumin content as output. The results showed that feed-forward ANN model with 8 nodes (MLFN-8 was the most suitable one with R2 value of 0.91. Sensitivity analysis revealed that minimum relative humidity, altitude, soil nitrogen content and soil pH had greater effect on curcumin content. This ANN model has shown proven efficiency for predicting and optimizing the curcumin content at a specific site.

  16. Variations by Audience Social Class in Newspaper Content Relating to Development for Newspapers in New Delhi, India.

    Science.gov (United States)

    Kent, Kurt

    Based on the assumption that newspapers mirror the conceptions of economic development among major groups in society and that analysis of their content may aid in the clarification of group viewpoints, two dimensions along which groups might differ with respect to their conceptions of economic development issues were postulated: the need for…

  17. Effects of heat stress on the endogenous contents of hormones and related gene expression in developing axillary tubes of potato

    Science.gov (United States)

    Potatoes are a cool season crop and optimum tuber initiation, development, yield, and quality require growing temperatures between 15 -20°C. At temperatures above 30°C, tuber initiation is delayed or prevented and developing tubers exhibit decreased starch content, increased malformation, chain-tube...

  18. Development of Curriculum Content for a Unique Career Ladder Multi-Entry/Multi-Exit Nursing Program. Final Report.

    Science.gov (United States)

    Rosbach, Ellen M.

    A project was undertaken to develop the curriculum content for a unique career ladder multi-entry/multi-exit nursing program that would provide training for nurse aides, practical nurses, and registered nurses. The major objectives of the project were to conduct a review of the literature on curriculum materials presently in use, to develop 11…

  19. Development and evaluation of a low cost probe-type instrument to measure the equilibrium moisture content of grain

    Science.gov (United States)

    Storage bags are common in Africa, Asia and many other less developed countries therefore a grain probing method is well-suited for moisture content (MC) measurement. A low cost meter was developed as part of a USAID project to reduce the post-harvest loss (PHL). The meter measures the MC of maize a...

  20. The Effects of Pollen Protein Content on Colony Development of the Bumblebee, Bombus Terrestris L.

    Directory of Open Access Journals (Sweden)

    Baloglu Güney Hikmet

    2015-06-01

    Full Text Available The effects of pollen protein content on the colony development of Bombus terrestris were investigated by feeding queens and queenright colonies with four different pollen diets. We used three kinds of commercially available pure pollen (Cistus spp. 11.9%, Papaver somniferum 21.4%, and Sinapis arvensis 21.8% crude protein. We also used a mixture which was made up of equal weights of these pure pollens (18.4 % crude protein. All queens and colonies were fed with sugar syrup and pollen diets ad libitum (28 ± 1 ℃, 65 ± 5% RH. Until there were 50 workers reached, colonies fed with the Cistus pollen diet (167.4 ± 28.9 g consumed significantly more pollen than colonies fed with the Papaver pollen diet (140.7 ± 15.7 g, the mixed pollen diet (136.2 ± 20.1 g or colonies fed with the Sinapis pollen diet (132.4 ± 22.6 g. The date when there were 50 workers reached was approximately one week later in the colonies fed with the Cistus, and colonies fed with the Papaver diet than in the colonies fed with the Sinapis diet, and for colonies fed with the mixed pollen diets. Considering 8 tested criteria, the best performances were observed using the Sinapis, and using the mixed pollen diets. The lowest performances were observed using the Cistus pollen diet. Results showed that pollen sources play an important role in commercial bumblebee rearing. Results also showed that the polyfloral pollen diets are more suitable for mass rearing of bumblebees than the unifloral pollen diets.

  1. Technical support for digital systems technology development. Task order 1: ISP contention analysis and control

    Science.gov (United States)

    Stehle, Roy H.; Ogier, Richard G.

    1993-01-01

    Alternatives for realizing a packet-based network switch for use on a frequency division multiple access/time division multiplexed (FDMA/TDM) geostationary communication satellite were investigated. Each of the eight downlink beams supports eight directed dwells. The design needed to accommodate multicast packets with very low probability of loss due to contention. Three switch architectures were designed and analyzed. An output-queued, shared bus system yielded a functionally simple system, utilizing a first-in, first-out (FIFO) memory per downlink dwell, but at the expense of a large total memory requirement. A shared memory architecture offered the most efficiency in memory requirements, requiring about half the memory of the shared bus design. The processing requirement for the shared-memory system adds system complexity that may offset the benefits of the smaller memory. An alternative design using a shared memory buffer per downlink beam decreases circuit complexity through a distributed design, and requires at most 1000 packets of memory more than the completely shared memory design. Modifications to the basic packet switch designs were proposed to accommodate circuit-switched traffic, which must be served on a periodic basis with minimal delay. Methods for dynamically controlling the downlink dwell lengths were developed and analyzed. These methods adapt quickly to changing traffic demands, and do not add significant complexity or cost to the satellite and ground station designs. Methods for reducing the memory requirement by not requiring the satellite to store full packets were also proposed and analyzed. In addition, optimal packet and dwell lengths were computed as functions of memory size for the three switch architectures.

  2. Development of Novel N-isopropylacrylamide (NIPAAm Based Hydrogels with Varying Content of Chrysin Multiacrylate

    Directory of Open Access Journals (Sweden)

    Shuo Tang

    2017-10-01

    Full Text Available A series of novel temperature responsive hydrogels were synthesized by free radical polymerization with varying content of chrysin multiacrylate (ChryMA. The goal was to study the impact of this novel polyphenolic-based multiacrylate on the properties of N-isopropylacrylamide (NIPAAm hydrogels. The temperature responsive behavior of the copolymerized gels was characterized by swelling studies, and their lower critical solution temperature (LCST was characterized through differential scanning calorimetry (DSC. It was shown that the incorporation of ChryMA decreased the swelling ratios of the hydrogels and shifted their LCSTs to a lower temperature. Gels with different ChryMA content showed different levels of response to temperature change. Higher content gels had a broader phase transition and smaller temperature response, which could be attributed to the increased hydrophobicity being introduced by the ChryMA.

  3. Development of SSR Markers Linked to Low Hydrocyanic Acid Content in Sorghum-Sudan Grass Hybrid Based on BSA Method.

    Science.gov (United States)

    Xiao-Xia, Yu; Zhi-Hua, Liu; Zhuo, Yu; Yue, Shi; Xiao-Yu, Li

    2016-01-01

    Sorghum-Sudan grass hybrid containing high hydrocyanic acid content can cause hydrocyanic acid poisoning to the livestock and limit the popularization of this forage crop. Molecular markers associated with low hydrocyanic acid content can speed up the process of identification of genotypes with low hydrocyanic acid content. In the present study, 11 polymorphic SSR primers were screened and used for bulked segregant analysis and single marker analysis. Three SSR markers Xtxp7230, Xtxp7375 and Bnlg667960 associated with low hydrocyanic acid content were rapidly identified by BSA. In single marker analysis, six markers Xtxp7230, Xtxp7375, Bnlg667960, Xtxp67-11, Xtxp295-7 and Xtxp12-9 were linked to low hydrocyanic acid content, which explained the proportion of phenotypic variation from 7.6 % to 41.2 %. The markers identified by BSA were also verified by single marker analysis. The three SSR marker bands were then cloned and sequenced for sequence homology analysis in NCBI. It is the first report on the development of molecular markers associated with low hydrocyanic acid content in sorghum- Sudan grass hybrid. These markers will be useful for genetic improvement of low hydrocyanic acid sorghum-Sudan grass hybrid by marker-assisted breeding.

  4. Development of a differential infrared absorption method to measure the deuterium content of natural water

    International Nuclear Information System (INIS)

    D'Alessio, Enrique; Bonadeo, Hernan; Karaianev de Del Carril, Stiliana.

    1975-07-01

    A system to measure the deuterium content of natural water using differential infrared spectroscopy is described. Parameters conducing to an optimized design are analyzed, and the construction of the system is described. A Perkin Elmer 225 infrared spectrometer, to which a scale expansion system has been added, is used. Sample and reference waters are alternatively introduced by a pneumatical-mechanical system into a unique F Ca thermostatized infrared cell. Results and calibration curves shown prove that the system is capable of measuring deuterium content with a precision of 1 part per million. (author)

  5. The development of Facebook marketing utilizing Content marketing. Case: Pirjon Pakari Oy.

    OpenAIRE

    Lehtikangas, Pauliina

    2015-01-01

    The purpose of this thesis was to learn how to improve Pirjon Pakari Oy’s brand visibility and overall visibility on Facebook. This was done by trying to add value to the end customer by producing interesting and engaging posts to Pirjon Pakari Oy’s Facebook page. This case study utilized theory from content marketing in attempts to improve the marketing of “Pirjon” Facebook page and therefore a Facebook content marketing strategy was created for Pirjon Pakari Oy. This strategy was implemente...

  6. Health promotion at local level: a case study of content, organization and development in four Swedish municipalities

    Directory of Open Access Journals (Sweden)

    Jansson Elisabeth VG

    2010-08-01

    Full Text Available Abstract Background Several health determinants are related to local conditions and prerequisites at community level. For this reason, strengthening community action has been one of five strategies implemented in health promotion since the end of the 1980s. Such action includes setting priorities, making decisions, planning strategies, and implementing them to achieve better health. The aim of this paper is to obtain a deeper understanding of content, organization and processes in the development of local health promotion. Methods A qualitative multiple case study of four Swedish municipalities. The cases were analyzed in accordance with the principles of cross-case study analysis, and a content analysis of documents and interviews was conducted in two steps. First, a manifest content analysis was performed to identify present and former actors and measures. Thereafter, a latent content analysis was performed to investigate structures and processes in local contexts. Results The results of the inductive content analysis showed development of local health promotion in three phases: initiation, action, and achievement. Strengthening factors were local actors, health statistics and events. Hindering factors were lack of resources and vague objectives. External factors, e.g. national policies, were not perceived as prominent influencing factors. Media reports were regarded as having had an influence, but only to some extent. The content of local health promotion has developed from ad-hoc lifestyle and behaviour-related actions into structural, intersectoral actions related to determinants of health. Conclusions The municipalities have organized and developed their health promotion targets, actions and priorities on the basis of local needs and prerequisites. The three phases in the identified health promotion processes were experienced and documented as being subject to greater influence from internal rather than external strengthening and hindering

  7. Developing Technological Pedagogical Content Knowledge in pre-service science teachers: Support from blended learning

    NARCIS (Netherlands)

    Alayyar, G.; Fisser, Petra; Voogt, Joke

    2012-01-01

    The Technological Pedagogical Content Knowledge (TPACK) framework has been used to prepare pre-service science teachers at the Public Authority of Applied Education and Training in Kuwait for ICT integration in education. Pre-service teachers worked in teams to design an ICT solution for an

  8. Developing Technological Pedagogical Content Knowledge in Pre-Service Science Teachers: Support from Blended Learning

    Science.gov (United States)

    Alayyar, Ghaida M.; Fisser, Petra; Voogt, Joke

    2012-01-01

    The "Technological Pedagogical Content Knowledge" (TPACK) framework has been used to prepare pre-service science teachers at the Public Authority of Applied Education and Training in Kuwait for ICT integration in education. Pre-service teachers worked in teams to design an ICT solution for an authentic problem they faced during in-school…

  9. ICT use in science and mathematics teacher education in Tanzan: Developing Technological Pedagogical Content Knowledge

    NARCIS (Netherlands)

    Kafyulilo, A.; Fisser, P.; Pieters, J.; Voogt, J.

    2015-01-01

    Currently, teacher education colleges in Tanzania are being equipped with computers to prepare teachers who can integrate technology in teaching. Despite these efforts, teachers are not embracing the use of technology in their teaching. This study adopted Technological Pedagogical Content Knowledge

  10. Pedagogical Content Knowledge for World History Teachers: What Is It? How Might Prospective Teachers Develop It?

    Science.gov (United States)

    Harris, Lauren McArthur; Bain, Robert B.

    2011-01-01

    This article takes up the question of world history teachers' pedagogical content knowledge by reporting on two separate but related projects. In the first, we briefly discuss an empirical investigation one of the authors conducted into the ways that pre- and in-service world history teachers think about, organize, and make meaning of separate and…

  11. ICT Use in Science and Mathematics Teacher Education in Tanzania: Developing Technological Pedagogical Content Knowledge

    NARCIS (Netherlands)

    Kafyulilo, Ayoub; Fisser, Petra; Pieters, Julius Marie; Voogt, Joke

    2015-01-01

    Currently, teacher education colleges in Tanzania are being equipped with computers to prepare teachers who can integrate technology in teaching. Despite these efforts, teachers are not embracing the use of technology in their teaching. This study adopted Technological Pedagogical Content Knowledge

  12. Developing Technological Pedagogical Content Knowledge in pre-service science teachers : Support from blended learning

    NARCIS (Netherlands)

    Alayyar, G.; Fisser, Petra; Voogt, Joke

    2012-01-01

    The Technological Pedagogical Content Knowledge (TPACK) framework has been used to prepare pre-service science teachers at the Public Authority of Applied Education and Training in Kuwait for ICT integration in education. Pre-service teachers worked in teams to design an ICT solution for an

  13. Development of a youth-report measure of DPN symptoms: Conceptualization and content validation

    Directory of Open Access Journals (Sweden)

    Joanne Moser

    2017-09-01

    Conclusions: This study is the first to generate a content valid self-report measure of youth’s lived experiences with DPN that uses developmentally appropriate terminology. With further psychometric testing, the measure could be used to advance research on pediatric DPN and enhance clinicians’ capacity to identify the condition in childhood.

  14. The Politics of Developing and Maintaining Mathematics and Science Curriculum Content Standards. Research Monograph.

    Science.gov (United States)

    Kirst, Michael W.; Bird, Robin L.

    The movement toward math and science curriculum standards is inextricably linked with high-stakes politics. There are two major types of politics discussed in this paper: the allocation of curriculum content, and the political issues involved in systemic change. Political strategies for gaining assent to national, state, and local content…

  15. Qualitative Research in Career Development: Content Analysis from 1990 to 2009

    Science.gov (United States)

    Stead, Graham B.; Perry, Justin C.; Munka, Linda M.; Bonnett, Heather R.; Shiban, Abbey P.; Care, Esther

    2012-01-01

    A content analysis of 11 journals that published career, vocational, and work-related articles from 1990 to 2009 was conducted. Of 3,279 articles analyzed, 55.9% used quantitative methods and 35.5% were theoretical/conceptual articles. Only 6.3% used qualitative research methods. Among the qualitative empirical studies, standards of academic rigor…

  16. Influences on the Struggle over Content: Considering Two Fine Art Studio Practice Curricula in Developing/ed Contexts

    Science.gov (United States)

    Belluigi, Dina Zoe

    2016-01-01

    This paper considers the influences of curricula content on the nuances of teaching and learning practices, and the ways in such influences are complicated by the contexts within which they are situated. Generated data from within the particularity of two fine art schools, one operating from the developed world in the global "north" and…

  17. Developing and Enacting Pedagogical Content Knowledge for Teaching History: An Exploration of Two Novice Teachers' Growth over Three Years

    Science.gov (United States)

    Monte-Sano, Chauncey; Budano, Christopher

    2013-01-01

    Using artifacts of teachers' practices, classroom observations, and teacher interviews, we explore the development and enactment of 2 novices' pedagogical content knowledge (PCK) for teaching history. We identify and track 4 components of PCK that are relevant to teaching history: representing history, transforming history, attending to students'…

  18. The Compatibility of Developed Mathematics Textbooks' Content in Saudi Arabia (Grades 6-8) with NCTM Standards

    Science.gov (United States)

    Alshehri, Mohammed Ali; Ali, Hassan Shawki

    2016-01-01

    This study aimed to investigate the compatibility of developed mathematics textbooks' content (grades 6-8) in Saudi Arabia with NCTM standards in the areas of: number and operations, algebra, geometry, measurement, data analysis and probability. To achieve that goal, a list of (NCTM) standards for grades (6-8) were translated to Arabic language,…

  19. Supporting teachers’ collaboration in design teams to develop Technological Pedagogical Content Knowledge: the case of science teachers in Tanzania

    NARCIS (Netherlands)

    Kafyulilo, Ayoub; Fisser, Petra; Voogt, Joke; McBride, R.; Searson, M.

    2013-01-01

    This study assessed the effect of support on the teachers’ collaboration in design teams and development of Technological Pedagogical Content Knowledge (TPACK). The study was carried out in two secondary schools in Tanzania: Chang’ombe and Jitegemee secondary schools. From each school 10 teachers

  20. Developing Pre-Service Teachers' Technological Pedagogical Content Knowledge for Teaching Mathematics with the Geometer's Sketchpad through Lesson Study

    Science.gov (United States)

    Meng, Chew Cheng; Sam, Lim Chap

    2013-01-01

    The purpose of this study was to develop pre-service secondary teachers' technological pedagogical content knowledge (TPACK) for teaching mathematics with The Geometer's Sketchpad (GSP) through Lesson Study (LS). Specifically, a single-group pretest-posttest design was employed to examine whether there was a significant difference in the…

  1. Sodium content and sodium efflux of mononuclear leucocytes from young subjects at increased risk of developing essential hypertension

    DEFF Research Database (Denmark)

    Pedersen, K E; Nielsen, J R; Klitgaard, N A

    1990-01-01

    Mononuclear leucocytes were used as a cellular model for the in vitro measurements of volume, sodium and potassium content, sodium efflux rate constants and absolute sodium efflux in order to assess any cellular changes in young men at increased risk of developing essential hypertension...

  2. Materials development and field demonstration of high-recycled-content concrete for energy-efficient building construction; FINAL

    International Nuclear Information System (INIS)

    Ostowari, Ken; Nosson, Ali

    2000-01-01

    The project developed high-recycled-content concrete material with balanced structural and thermal attributes for use in energy-efficient building construction. Recycled plastics, tire, wool, steel and concrete were used as replacement for coarse aggregates in concrete and masonry production. With recycled materials the specific heat and thermal conductivity of concrete could be tailored to enhance the energy-efficiency of concrete buildings. A comprehensive field project was implemented which confirmed the benefits of high-recycled-content concrete for energy-efficient building construction

  3. Patient experiences with oily skin: The qualitative development of content for two new patient reported outcome questionnaires

    OpenAIRE

    Arbuckle, Robert; Atkinson, Mark J; Clark, Marci; Abetz, Linda; Lohs, Jan; Kuhagen, Ilka; Harness, Jane; Draelos, Zoe; Thiboutot, Diane; Blume-Peytavi, Ulrike; Copley-Merriman, Kati

    2008-01-01

    Abstract Objective To develop the content for two new patient reported outcome (PRO) measures to: a) assess the severity of symptoms; and b) the impact of facial skin oiliness on emotional wellbeing using qualitative data from face to face, and internet focus groups in Germany and the US. Methods Using input from initial treatment satisfaction focus groups (n = 42), a review of relevant literature and expert clinicians (n = 3), a discussion guide was developed to guide qualitative inquiry usi...

  4. Development of unified X-ray fluorescent analysis to determine rhenium content in multicomponent oxide compositions

    International Nuclear Information System (INIS)

    Drobot, D.V.; Belyaev, A.V.; Kutvitskij, V.A.; Rysev, A.P.

    1999-01-01

    A procedure to prepare rhenium-containing glass-like specimens on the basis of bismuth and boron oxides is proposed. The glasses produced are studied by X-ray fluorescent analysis and routine spectrometric thiocyanate analysis. The results make it possible to determine rhenium in oxide mixtures in the range of its content 0.01 - 10% with S r = 0.03 [ru

  5. A multimedia mobile phone-based youth smoking cessation intervention: findings from content development and piloting studies.

    Science.gov (United States)

    Whittaker, Robyn; Maddison, Ralph; McRobbie, Hayden; Bullen, Chris; Denny, Simon; Dorey, Enid; Ellis-Pegler, Mary; van Rooyen, Jaco; Rodgers, Anthony

    2008-11-25

    While most young people who smoke want to quit, few access cessation support services. Mobile phone-based cessation programs are ideal for young people: mobile phones are the most common means of peer communication, and messages can be delivered in an anonymous manner, anywhere, anytime. Following the success of our text messaging smoking cessation program, we developed an innovative multimedia mobile phone smoking cessation intervention. The aim of the study was to develop and pilot test a youth-oriented multimedia smoking cessation intervention delivered solely by mobile phone. Development included creating content and building the technology platform. Content development was overseen by an expert group who advised on youth development principles, observational learning (from social cognitive theory), effective smoking cessation interventions, and social marketing. Young people participated in three content development phases (consultation via focus groups and an online survey, content pre-testing, and selection of role models). Video and text messages were then developed, incorporating the findings from this research. Information technology systems were established to support the delivery of the multimedia messages by mobile phone. A pilot study using an abbreviated 4-week program of video and text content tested the reliability of the systems and the acceptability of the intervention. Approximately 180 young people participated in the consultation phase. There was a high priority placed on music for relaxation (75%) and an interest in interacting with others in the program (40% would read messages, 36% would read a blog). Findings from the pre-testing phase (n = 41) included the importance of selecting "real" and "honest" role models with believable stories, and an interest in animations (37%). Of the 15 participants who took part in the pilot study, 13 (87%) were available for follow-up interviews at 4 weeks: 12 participants liked the program or liked it most

  6. Development of a Dunaliella tertiolecta Strain with Increased Zeaxanthin Content Using Random Mutagenesis.

    Science.gov (United States)

    Kim, Minjae; Ahn, Junhak; Jeon, Hancheol; Jin, EonSeon

    2017-06-21

    Zeaxanthin is a xanthophyll pigment that is regarded as one of the best carotenoids for the prevention and treatment of degenerative diseases. In the worldwide natural products market, consumers prefer pigments that have been produced from biological sources. In this study, a Dunaliella tertiolecta strain that has 10-15% higher cellular zeaxanthin content than the parent strain ( zea1 ), was obtained by random mutagenesis using ethyl methanesulfonate (EMS) as a mutagen. This mutant, mp3 , was grown under various salinities and light intensities to optimize culture conditions for zeaxanthin production. The highest cellular zeaxanthin content was observed at 1.5 M NaCl and 65-85 μmol photons·m -2 ·s -1 , and the highest daily zeaxanthin productivity was observed at 0.6 M NaCl and 140-160 μmol photons·m -2 ·s -1 . The maximal yield of zeaxanthin from mp3 in fed-batch culture was 8 mg·L -1 , which was obtained at 0.6 M NaCl and 140-160 μmol photons·m -2 ·s -1 . These results suggest that random mutagenesis with EMS is useful for generating D. tertiolecta strains with increased zeaxanthin content, and also suggest optimal culture conditions for the enhancement of biomass and zeaxanthin production by the zeaxanthin accumulating mutant strains.

  7. Fat and Moisture Content in Chinese Fried Bread Sticks: Assessment and Rapid Near-Infrared Spectroscopic Method Development

    Directory of Open Access Journals (Sweden)

    Zhuqing Xiao

    2013-01-01

    Full Text Available Fried bread sticks (FBS are one of the most widely consumed deep fried food products in China. Understanding the fat and moisture content in FBS will help consumers make healthy food choices as well as assist food processors to provide FBS with desirable quality. Rapid Fourier transform near-infrared methods (FT-NIR were developed for determining fat and moisture content in FBS collected from 123 different vendors in Shanghai, China. FBS samples with minimum sample preparation (either finely or coarsely ground were used for NIR analyses. Spectra of FBS were treated with different mathematic pretreatments before being used to build models between the spectral information and fat (7.71%–30.89% or moisture (17.39%–32.65% content in FBS. Finely ground samples may lead to slightly more robust PLS models, but the particle sizes of ground FBS samples did not seriously affect the predictability of the models with appropriate mathematical treatments. The fat and moisture content in FBS predicted by FT-NIR methods had very good correlation with their values determined via traditional methods (fat, R2=0.965; moisture, R2=0.983, which clearly indicated that FT-NIR methods could be used as an effective tool for rapid determination of fat and moisture content in FBS.

  8. Developing Distinct Mathematical and Scientific Pedagogical Content Knowledge in an Early Childhood Dual-Content Methods Course: An Alternative to Integration

    Science.gov (United States)

    Kalchman, Mindy; Kozoll, Richard H.

    2017-01-01

    Methods for teaching early childhood mathematics and science are often addressed in a single, dual-content course. Approaches to teaching this type of course include integrating the content and the pedagogy of both subjects, or keeping the subject areas distinct. In this article, the authors discuss and illustrate their approach to such a combined…

  9. Developing a NIR multispectral imaging for prediction and visualization of peanut protein content using variable selection algorithms

    Science.gov (United States)

    Cheng, Jun-Hu; Jin, Huali; Liu, Zhiwei

    2018-01-01

    The feasibility of developing a multispectral imaging method using important wavelengths from hyperspectral images selected by genetic algorithm (GA), successive projection algorithm (SPA) and regression coefficient (RC) methods for modeling and predicting protein content in peanut kernel was investigated for the first time. Partial least squares regression (PLSR) calibration model was established between the spectral data from the selected optimal wavelengths and the reference measured protein content ranged from 23.46% to 28.43%. The RC-PLSR model established using eight key wavelengths (1153, 1567, 1972, 2143, 2288, 2339, 2389 and 2446 nm) showed the best predictive results with the coefficient of determination of prediction (R2P) of 0.901, and root mean square error of prediction (RMSEP) of 0.108 and residual predictive deviation (RPD) of 2.32. Based on the obtained best model and image processing algorithms, the distribution maps of protein content were generated. The overall results of this study indicated that developing a rapid and online multispectral imaging system using the feature wavelengths and PLSR analysis is potential and feasible for determination of the protein content in peanut kernels.

  10. Development and content validity of a patient reported outcomes measure to assess symptoms of major depressive disorder

    Directory of Open Access Journals (Sweden)

    Lasch Kathryn

    2012-04-01

    Full Text Available Abstract Background Although many symptoms of Major Depressive Disorder (MDD are assessed through patient-report, there are currently no patient-reported outcome (PRO instruments that incorporate documented evidence of patient input in PRO instrument development. A review of existing PROs used in MDD suggested the need to conduct qualitative research with patients with MDD to better understand their experience of MDD and develop an evaluative instrument with content validity. The aim of this study was to develop a disease-specific questionnaire to assess symptoms important and relevant to adult MDD patients. Methods The questionnaire development involved qualitative interviews for concept elicitation, instrument development, and cognitive interviews to support content validity. For concept elicitation, ten MDD severity-specific focus group interviews with thirty-eight patients having clinician-confirmed diagnoses of MDD were conducted in January 2009. A semi-structured discussion guide was used to elicit patients' spontaneous descriptions of MDD symptoms. Verbatim transcripts of focus groups were coded and analyzed to develop a conceptual framework to describe MDD. A PRO instrument was developed by operationalizing concepts elicited in the conceptual framework. Cognitive interviews were carried out in patients (n = 20 to refine and test the content validity of the instrument in terms of item relevance and comprehension, instructions, recall period, and response categories. Results Concept elicitation focus groups identified thirty-five unique concepts falling into several domains: i emotional, ii cognitive, iii motivation, iv work, v sleep, vi appetite, vii social, viii activities of daily living, ix tired/fatigue, x body pain, and xi suicidality. Concept saturation, the point at which no new relevant information emerges in later interviews, was achieved for each of the concepts. Based on the qualitative findings, the PRO instrument developed

  11. Development and content validity testing of a comprehensive classification of diagnoses for pediatric nurse practitioners.

    Science.gov (United States)

    Burns, C

    1991-01-01

    Pediatric nurse practitioners (PNPs) need an integrated, comprehensive classification that includes nursing, disease, and developmental diagnoses to effectively describe their practice. No such classification exists. Further, methodologic studies to help evaluate the content validity of any nursing taxonomy are unavailable. A conceptual framework was derived. Then 178 diagnoses from the North American Nursing Diagnosis Association (NANDA) 1986 list, selected diagnoses from the International Classification of Diseases, the Diagnostic and Statistical Manual, Third Revision, and others were selected. This framework identified and listed, with definitions, three domains of diagnoses: Developmental Problems, Diseases, and Daily Living Problems. The diagnoses were ranked using a 4-point scale (4 = highly related to 1 = not related) and were placed into the three domains. The rating scale was assigned by a panel of eight expert pediatric nurses. Diagnoses that were assigned to the Daily Living Problems domain were then sorted into the 11 Functional Health patterns described by Gordon (1987). Reliability was measured using proportions of agreement and Kappas. Content validity of the groups created was measured using indices of content validity and average congruency percentages. The experts used a new method to sort the diagnoses in a new way that decreased overlaps among the domains. The Developmental and Disease domains were judged reliable and valid. The Daily Living domain of nursing diagnoses showed marginally acceptable validity with acceptable reliability. Six Functional Health Patterns were judged reliable and valid, mixed results were determined for four categories, and the Coping/Stress Tolerance category was judged reliable but not valid using either test. There were considerable differences between the panel's, Gordon's (1987), and NANDA's clustering of NANDA diagnoses. This study defines the diagnostic practice of nurses from a holistic, patient

  12. Development of a Coding Instrument to Assess the Quality and Content of Anti-Tobacco Video Games

    Science.gov (United States)

    Alber, Julia M.; Watson, Anna M.; Barnett, Tracey E.; Mercado, Rebeccah

    2015-01-01

    Abstract Previous research has shown the use of electronic video games as an effective method for increasing content knowledge about the risks of drugs and alcohol use for adolescents. Although best practice suggests that theory, health communication strategies, and game appeal are important characteristics for developing games, no instruments are currently available to examine the quality and content of tobacco prevention and cessation electronic games. This study presents the systematic development of a coding instrument to measure the quality, use of theory, and health communication strategies of tobacco cessation and prevention electronic games. Using previous research and expert review, a content analysis coding instrument measuring 67 characteristics was developed with three overarching categories: type and quality of games, theory and approach, and type and format of messages. Two trained coders applied the instrument to 88 games on four platforms (personal computer, Nintendo DS, iPhone, and Android phone) to field test the instrument. Cohen's kappa for each item ranged from 0.66 to 1.00, with an average kappa value of 0.97. Future research can adapt this coding instrument to games addressing other health issues. In addition, the instrument questions can serve as a useful guide for evidence-based game development. PMID:26167842

  13. Development of a Coding Instrument to Assess the Quality and Content of Anti-Tobacco Video Games.

    Science.gov (United States)

    Alber, Julia M; Watson, Anna M; Barnett, Tracey E; Mercado, Rebeccah; Bernhardt, Jay M

    2015-07-01

    Previous research has shown the use of electronic video games as an effective method for increasing content knowledge about the risks of drugs and alcohol use for adolescents. Although best practice suggests that theory, health communication strategies, and game appeal are important characteristics for developing games, no instruments are currently available to examine the quality and content of tobacco prevention and cessation electronic games. This study presents the systematic development of a coding instrument to measure the quality, use of theory, and health communication strategies of tobacco cessation and prevention electronic games. Using previous research and expert review, a content analysis coding instrument measuring 67 characteristics was developed with three overarching categories: type and quality of games, theory and approach, and type and format of messages. Two trained coders applied the instrument to 88 games on four platforms (personal computer, Nintendo DS, iPhone, and Android phone) to field test the instrument. Cohen's kappa for each item ranged from 0.66 to 1.00, with an average kappa value of 0.97. Future research can adapt this coding instrument to games addressing other health issues. In addition, the instrument questions can serve as a useful guide for evidence-based game development.

  14. Development of a melatonin RIA and observation on the plasma melatonin contents in rat models of chronic hyperirritable-depression

    International Nuclear Information System (INIS)

    Rong Yang; Sun Acheng; Ma Cong; Zhao Zhong; Gui Yuning; Li Jianjun; Wang Guangkai; Guo Xiazhen

    2005-01-01

    Objective: To establish a new melatonin assay and to investigate the changes of plasma melatonin content in rat models of chronic hyperirritable-depression. Methods: Quality melatonin antiserum was obtained from immunization of Newzealand white rabbit with melatonin immunogen derived from conjugation of melatonin to bovine thyroglobulin using formaldehyde. Radioiodinated melatonin was used as tracer and a melatonin assay was developed through non-equilibrium competition. Twenty rat models of chronic hyperirritable-depression were prepared with multiple randomly-combined stimuli as previously reported. Plasma and pineal body tissue contents of melatonin in the models were examined in midsummer (n=10) and mid-winter (n=10) with the newly developed melatonin RIA. Contents of melatonin were also determined in 20 control rats. Results: The antiserum possessed very low cross-reaction rate with several melatonin analogous tested (0.09%-2.3%). At the titer of 1:1800, the maximal combination rate was 41%. The affinity constant was 1.7 x 10 9 L/M. The specific radioactivity of the tracer 125 I-melatonin was 55 μCi/μg, with radio-chemical purity of 93% and the tracer was stable at 4 degree C for 65 days. The assay was of high sensitivity (lower detection limit 5pg/ml), intra-CV, 6.5 %; inter-CV, 11%. The plasma and pineal body tissue contents of melatonin in the rat models were consistently significantly lower than those in control rats both during summer and winter, while the contents of melatonin during winter were always significantly higher than those during summer in both groups of animals. Conclusion: The newly developed assay was of good specificity and sensitivity with stable agents (65 days). The experimental results demonstrated definite correlationship between the depression disorder and melatonin contents in the rat models, however, the disorder was not seasonally affective. The seasonal variation of the melatonin contents in the animals was due to different

  15. Content and cultural validity in the development of the Indigenous Play Partner Scale.

    Science.gov (United States)

    Dender, Alma M; Stagnitti, Karen E

    2017-08-01

    Culturally relevant assessments of Australian Indigenous children's social pretend play do not exist. This study investigated the content validity and cultural validity of the Indigenous Play Partner Scale (I-PPS). Six pairs of children (i.e. 12 children) aged four-six years from a remote Australian town were videoed playing in pairs, and 14 community elders and mothers participated across three focus groups. The social interactions between the children were transcribed from the videos. Nineteen verbs, grouped into five categories of social interaction, described the social interactions between the pairs of children. The descriptions of the social interaction verbs were presented to the community elders and mothers in a focus group. The themes from the focus groups were 'background of Indigenous understanding of play' and 'proposed social interaction verbs'. The first theme reflected community collaboration, children playing in multi-aged groups and the role of older children within the play. Guided by the focus group discussion, the videos were re-analysed and 20 social interaction verbs were described that reflected the cultural context of play. The content and cultural validity of the I-PPS was established through community consultation. Twenty social interaction verbs, which form the basis of the items of the I-PPS, reflected Indigenous cultural values of being non-judgemental of Indigenous children's social interactions during pretend play. Culturally relevant assessments for Australian Indigenous children do not disadvantage this population group and are essential for practice in occupational therapy. © 2017 Occupational Therapy Australia.

  16. Developing a Conceptual Framework for Evaluation of E-Content of Virtual Courses: E-Learning Center of an Iranian University Case Study

    Science.gov (United States)

    Akhavan, Peyman; Arefi, Majid Feyz

    2014-01-01

    The purpose of this study is to obtain suitable quality criteria for evaluation of electronic content for virtual courses. We attempt to find the aspects which are important in developing e-content for virtual courses and to determine the criteria we need to judge for the quality and efficiency of learning objects and e-content. So we can classify…

  17. A Content Analysis of Acculturation Research in the Career Development Literature

    Science.gov (United States)

    Miller, Matthew J.; Kerlow-Myers, Andrew E.

    2009-01-01

    The purpose of the present study was to highlight the importance of acculturation as an explanatory variable in career development and to provide an empirical review of acculturation research in the career development literature. Acculturation is a cultural variable that has been linked to a number of important career development outcomes for…

  18. Assessing College Students' Perceptions of a Case Teacher's Pedagogical Content Knowledge Using a Newly Developed Instrument

    Science.gov (United States)

    Jang, Syh-Jong

    2011-01-01

    Ongoing professional development for college teachers has been much emphasized. However, previous research on learning environments has seldom addressed college students' perceptions of teachers' PCK. This study aimed to evaluate college students' perceptions of a physics teacher's PCK development using a newly developed instrument and workshop…

  19. Culture as a Prerequisite for Sustainable Development. An Investigation into the Process of Cultural Content Digitisation in Romania

    Directory of Open Access Journals (Sweden)

    Mina Fanea-Ivanovici

    2018-06-01

    Full Text Available In an age of rapid technological changes, new ways of cultural production–consumption and dissemination–access to cultural content are creating great opportunities for promoting cultural heritage at home and abroad as a prerequisite for sustainable development. The aims of this paper are to scrutinize the main opportunities of the process of cultural content digitisation with a focus on Romania and to highlight the main fields in which the country is still lagging behind. The article discusses technical internet-related endowment and use of internet by households in urban and rural areas, the existing digital cultural content, the importance of open access, e-accessibility, digital archives, e-museums, e-libraries, etc., as well as the main national and European strategies and agendas that Romania has based its cultural digitisation and heritage preservation priorities on. The paper is an empirical inquiry into the progress achieved, the positioning among the other European countries and the perspectives of cultural digitisation for Romania. Such matters are important determinants of smart, sustainable and inclusive growth, as long as access to public services and cultural content is a major objective of Europe 2020 Strategy.

  20. Peet, R., Hartwick E. – Theories of development: Contentions, Arguments, Alternatives

    Directory of Open Access Journals (Sweden)

    Manuela Epure

    2015-12-01

    Full Text Available This book review aims to discuss the new perspectives on theories of development provided by two outstanding scholars: Richard Peet and Elaine Hartwick in their recent published book “Theories of development: Contestations, Arguments, Alternatives”. An interesting point a view is presented from the beginning: development means a better life for everyone but economic growth can occur without touching problems like inequalities, poverty etc. The introductory chapter explains the differences between Growth and Development, and it is followed by a part I Conventional Theories of Development, part II Nonconventional Critical Theories of Development, part III Critical Modernism. Readers will find this book review intriguing and interesting enough to stimulate their curiosity to explore this fascinating book.

  1. Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis.

    Science.gov (United States)

    Deal, Samantha; Wambaugh, John; Judson, Richard; Mosher, Shad; Radio, Nick; Houck, Keith; Padilla, Stephanie

    2016-09-01

    One of the rate-limiting procedures in a developmental zebrafish screen is the morphological assessment of each larva. Most researchers opt for a time-consuming, structured visual assessment by trained human observer(s). The present studies were designed to develop a more objective, accurate and rapid method for screening zebrafish for dysmorphology. Instead of the very detailed human assessment, we have developed the computational malformation index, which combines the use of high-content imaging with a very brief human visual assessment. Each larva was quickly assessed by a human observer (basic visual assessment), killed, fixed and assessed for dysmorphology with the Zebratox V4 BioApplication using the Cellomics® ArrayScan® V(TI) high-content image analysis platform. The basic visual assessment adds in-life parameters, and the high-content analysis assesses each individual larva for various features (total area, width, spine length, head-tail length, length-width ratio, perimeter-area ratio). In developing the computational malformation index, a training set of hundreds of embryos treated with hundreds of chemicals were visually assessed using the basic or detailed method. In the second phase, we assessed both the stability of these high-content measurements and its performance using a test set of zebrafish treated with a dose range of two reference chemicals (trans-retinoic acid or cadmium). We found the measures were stable for at least 1 week and comparison of these automated measures to detailed visual inspection of the larvae showed excellent congruence. Our computational malformation index provides an objective manner for rapid phenotypic brightfield assessment of individual larva in a developmental zebrafish assay. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  2. Historical Development of Newton's Laws of Motion and Suggestions for Teaching Content

    Science.gov (United States)

    Chang, Wheijen; Bell, Beverley; Jones, Allister

    2014-01-01

    A review of the history of Newton's Laws of Motion illustrates that the historical development gradually shifted away from intuitive experiences and daily life conventions towards a scientific regulated perspective. Three stages of the historical development are discussed, i.e. prior to the Principia, the 3rd (last) edition of the Principia,…

  3. The Nigeria Teachers Social Studies Training Curriculum and Sustainable Development Goals: A Content Analysis

    Science.gov (United States)

    Ifegbesan, Ayodeji P.; Lawal, M. B.; Rampedi, Isaac T.

    2017-01-01

    The concept of sustainable development has become a widely used construct that is incorporated into virtually all disciplines and discourses. The implementation and achievement of sustainable development goals in the management of our environmental resources cannot be realized without education, especially at a formal level. Teacher training…

  4. A 10-Year Mechatronics Curriculum Development Initiative: Relevance, Content, and Results--Part II

    Science.gov (United States)

    Krishnan, M.; Das, S.; Yost, S. A.

    2010-01-01

    This paper describes the second and third phases of a comprehensive mechatronics curriculum development effort. They encompass the development of two advanced mechatronics courses ("Simulation and Modeling of Mechatronic Systems" and "Sensors and Actuators for Mechatronic Systems"), the formulation of a Mechatronics concentration, and offshoot…

  5. 23 CFR 450.214 - Development and content of the long-range statewide transportation plan.

    Science.gov (United States)

    2010-04-01

    ...., transportation, safety, economic development, social and environmental effects, or energy) that were relevant to... time of adoption, that provides for the development and implementation of the multimodal transportation... consultation with affected non-metropolitan officials with responsibility for transportation using the State's...

  6. Core Content for Wilderness Medicine Training: Development of a Wilderness Medicine Track Within an Emergency Medicine Residency.

    Science.gov (United States)

    Schrading, Walter A; Battaglioli, Nicole; Drew, Jonathan; McClure, Sarah Frances

    2018-03-01

    Wilderness medicine training has become increasingly popular among medical professionals with numerous educational opportunities nationwide. Curricula for fellowship programs and for medical student education have previously been developed and published, but a specific curriculum for wilderness medicine education during emergency medicine (EM) residency has not. The objective of this study is to create a longitudinal wilderness medicine curriculum that can be incorporated into an EM residency program. Interest-specific tracks are becoming increasingly common in EM training. We chose this model to develop our curriculum specific to wilderness medicine. Outlined in the article is a 3-year longitudinal course of study that includes a core didactic curriculum and a plan for graduated level of responsibility. The core content is specifically related to the required EM core content for residency training with additions specific to wilderness medicine for the residents who pursue the track. The wilderness medicine curriculum would give residencies a framework that can be used to foster learning for residents interested in wilderness medicine. It would enhance the coverage of wilderness and environmental core content education for all EM residents in the program. It would provide wilderness-specific education and experience for interested residents, allowing them to align their residency program requirements through a focused area of study and enhancing their curriculum vitae at graduation. Finally, given the popularity of wilderness medicine, the presence of a wilderness medicine track may improve recruitment for the residency program. Copyright © 2017 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  7. Development and content validity of a screening instrument for gaming addiction in adolescents: the Gaming Addiction Identification Test (GAIT).

    Science.gov (United States)

    Vadlin, Sofia; Åslund, Cecilia; Nilsson, Kent W

    2015-08-01

    This study describes the development of a screening tool for gaming addiction in adolescents - the Gaming Addiction Identification Test (GAIT). Its development was based on the research literature on gaming and addiction. An expert panel comprising professional raters (n = 7), experiential adolescent raters (n = 10), and parent raters (n = 10) estimated the content validity of each item (I-CVI) as well as of the whole scale (S-CVI/Ave), and participated in a cognitive interview about the GAIT scale. The mean scores for both I-CVI and S-CVI/Ave ranged between 0.97 and 0.99 compared with the lowest recommended I-CVI value of 0.78 and the S-CVI/Ave value of 0.90. There were no sex differences and no differences between expert groups regarding ratings in content validity. No differences in the overall evaluation of the scale emerged in the cognitive interviews. Our conclusions were that GAIT showed good content validity in capturing gaming addiction. The GAIT needs further investigation into its psychometric properties of construct validity (convergent and divergent validity) and criterion-related validity, as well as its reliability in both clinical settings and in community settings with adolescents. © 2015 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  8. Development of an Openmath Content Dictionary for Mathematical Knowledge of Materials Science and Engineering

    Directory of Open Access Journals (Sweden)

    Toshihiro Ashino

    2012-12-01

    Full Text Available Many relationships between parameters and physical properties in materials science and engineering are represented as mathematical expressions, such as empirical equations and regression expressions. Some materials databases handle such information with indirect methods: as a table of sets of parameters, as a list of statements of programming languages, and other ways. There is no standardized way to represent mathematical relationships, and that makes it difficult to exchange, process, and display such information. The AIST (National Institute of Advanced Industrial Science and Technology in Japan thermophysical property database manages sets of parameter values for expressions and Fortran statements that represent relationships between physical parameters, e.g., temperature, pressure, etc. and thermophysical properties. However, in this method, it is not easy to add new parameters, to process expressions, and exchange information with other software tools. In this paper, we describe the current implementation of representing mathematical knowledge in the AIST thermophysical property database, and we also discuss its problems, sample implementations, and definitions of the OpenMath content dictionary for materials science and engineering.

  9. EDUCATING TEACHERS FOR CONTENT AND LANGUAGE INTEGRATED LEARNING IN KAZAKHSTAN: DEVELOPING POSITIVE ATTITUDES

    Directory of Open Access Journals (Sweden)

    Artyom Sergeyevich Dontsov

    2018-04-01

    Full Text Available The aim of the present research is to identify whether teachers' attitudes towards the use of Content and Language Integrated Learning (CLIL in the Republic of Kazakhstan can undergo significant changes if they study a course introducing them to the fundamentals of CLIL. Despite the country's plans to adopt English as one of the languages of education, stakeholders’ attitudes towards teaching through the medium of this language remain rather skeptical. A survey was held among Master’s degree students majoring in Education (n = 59 at Pavlodar State University before the course and after its completion. Since it is the affective component that largely determines the quality of attitudes, the levels of participants' anxiety, self-esteem and motivation were used as the indicators. The tools for measuring these variables were the State-Trait Anxiety Inventory, Dembo-Rubinstein's Method of Self-esteem Measurement and Dubovitskaya's Diagnostics of Learning Motivation Orientation. The end-of-course results show a marked reduction in the level of participants' state anxiety, a growth in self-esteem in terms of the readiness to use CLIL, and a shift towards intrinsic motivation. It is argued that for attitudes shift to take place, it is necessary to adopt a constructivist approach to teaching and learning.

  10. Development of a method to determine the total C-14 content in saturated salt solutions

    International Nuclear Information System (INIS)

    Lucks, C.; Prautsch, C.

    2016-01-01

    This two-step method described here for the determination of the total carbon-14 content in saturated salt solutions is divided in the analysis of the carbon-14 in the evaporable and the non-evaporable fraction. After driving off the inorganic carbon by acidification, the volatile carbon compounds and volatile decomposition products follow with rising temperature inside the sample vessel in a mild stream of oxygen to a tube furnace equipped with CuO catalyst for oxidizing the carbon compounds to CO 2 at a temperature of 800 C. Water is condensed out with an intensive condenser and the released CO 2 is absorbed in a wash bottle filled with sodium hydroxide. Similarly, an aliquot of the evaporation residue is put in the first zone of the tube furnace during the second step of the analysis. After heating the catalyst in the second zone of the furnace to 800 C the residue is heated stepwise to 800 C. By proceeding in this way, the non-volatile compounds are decomposed or oxidised in the oxygen stream and finally completely oxidized by the aid of the catalyst. The released CO 2 is again absorbed in another wash bottle. The carbonate of each fraction is then precipitated as BaCO 3 separately. Finally, the precipitate is washed, dried, finely grounded and covered with toluene scintillation cocktail for measurement in a LSC. The detection limit is about 0,2 Bq/l for a sample volume of 250 ml.

  11. Development of assessment methods for transport and storage containers with higher content of metallic recycling material

    International Nuclear Information System (INIS)

    Zencker, U.; Qiao Linan; Droste, B.

    2004-01-01

    The mechanical behaviour of transport and storage containers made of ductile cast iron melted with higher content of metallic recycling material from decommissioning and dismantling of nuclear installations is investigated. With drop tests of cubic container-like models, the influence of different real targets on the stresses in the cask body and the fracture behaviour is examined. A test stand foundation is suggested, which can be manufactured simply and improves the reproducibility of the test results strongly. The test objects are partially equipped with artificial cracklike defects. Dynamic fracture mechanics analyses of these defects were performed by means of finite element calculations to uncover safety margins. Numerous test results show depending on the requirements that containers for final disposal can be built by means of a ductile cast iron with fracture toughness more than half under the lower bound value for the licensed material qualities yet. The application limits of the material are determined also by the opportunities of the safety assessment methods. This project supports the application of brittle fracture safe transport and storage packages for radioactive materials as recommended in App. VI of the Advisory Material for the IAEA Regulations for the Safe Transport of Radioactive Material (IAEA No. TS-G-1.1)

  12. Development of assessment methods for transport and storage containers with higher content of metallic recycling material

    Energy Technology Data Exchange (ETDEWEB)

    Zencker, U.; Qiao Linan; Droste, B. [Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin (Germany)

    2004-07-01

    The mechanical behaviour of transport and storage containers made of ductile cast iron melted with higher content of metallic recycling material from decommissioning and dismantling of nuclear installations is investigated. With drop tests of cubic container-like models, the influence of different real targets on the stresses in the cask body and the fracture behaviour is examined. A test stand foundation is suggested, which can be manufactured simply and improves the reproducibility of the test results strongly. The test objects are partially equipped with artificial cracklike defects. Dynamic fracture mechanics analyses of these defects were performed by means of finite element calculations to uncover safety margins. Numerous test results show depending on the requirements that containers for final disposal can be built by means of a ductile cast iron with fracture toughness more than half under the lower bound value for the licensed material qualities yet. The application limits of the material are determined also by the opportunities of the safety assessment methods. This project supports the application of brittle fracture safe transport and storage packages for radioactive materials as recommended in App. VI of the Advisory Material for the IAEA Regulations for the Safe Transport of Radioactive Material (IAEA No. TS-G-1.1).

  13. Development and Content Validation of the Transition Readiness Inventory Item Pool for Adolescent and Young Adult Survivors of Childhood Cancer.

    Science.gov (United States)

    Schwartz, Lisa A; Hamilton, Jessica L; Brumley, Lauren D; Barakat, Lamia P; Deatrick, Janet A; Szalda, Dava E; Bevans, Katherine B; Tucker, Carole A; Daniel, Lauren C; Butler, Eliana; Kazak, Anne E; Hobbie, Wendy L; Ginsberg, Jill P; Psihogios, Alexandra M; Ver Hoeve, Elizabeth; Tuchman, Lisa K

    2017-10-01

    The development of the Transition Readiness Inventory (TRI) item pool for adolescent and young adult childhood cancer survivors is described, aiming to both advance transition research and provide an example of the application of NIH Patient Reported Outcomes Information System methods. Using rigorous measurement development methods including mixed methods, patient and parent versions of the TRI item pool were created based on the Social-ecological Model of Adolescent and young adult Readiness for Transition (SMART). Each stage informed development and refinement of the item pool. Content validity ratings and cognitive interviews resulted in 81 content valid items for the patient version and 85 items for the parent version. TRI represents the first multi-informant, rigorously developed transition readiness item pool that comprehensively measures the social-ecological components of transition readiness. Discussion includes clinical implications, the application of TRI and the methods to develop the item pool to other populations, and next steps for further validation and refinement. © The Author 2017. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  14. [Development of a high content protein beverage from Chilean mesquite, lupine and quinoa for the diet of pre-schoolers].

    Science.gov (United States)

    Cerezal Mezquita, P; Acosta Barrientos, E; Rojas Valdivia, G; Romero Palacios, N; Arcos Zavala, R

    2012-01-01

    This research was aimed at developing a high content protein beverage from the mixture of liquid extracts of a pseudocereal, quinoa (Chenopodium quinoa Willd) and two legumes: mesquite (Prosopis chilensis (Mol.) Stunz) and lupine (Lupinus albus L.), native from the Andean highlands of the Chilean northern macro-zone, flavored with raspberry pulp, to help in the feeding of children between 2 and 5 years of lower socioeconomic status with nutritional deficiencies. The formulation was defined by linear programming, its composition was determined by proximate analysis and physical, microbiological and sensory acceptance tests were performed. After 90 days of storage time, the beverage got a protein content of 1.36%, being tryptophan the limiting amino acid; for its part, the chromaticity coordinates of CIEL*a*b* color space showed no statistical significant differences (p < 0.05) maintaining the "dark pink" tonality, the viscosity and the sensory evaluation were acceptable for drinking.

  15. Effect of gamma irradiation on the total nitrogen and protein content in body during different stages of silkworm development

    International Nuclear Information System (INIS)

    Petkov, N.; Malinova, K.; Binkh, N.T.

    1996-01-01

    The aim was to determine the effect of gamma irradiation of eggs of silk moth in B 2 stage in doses of 1.00, 2.00 and 3.00 Gy on the changes of total nitrogen and protein content during different stages of Bombyx mori L. development. Highest levels of total nitrogen and protein were found in silk gland 14.032-14.355 mg%, followed by pupae - 7.448-8.092 and 46.550-48.906 mg%, moths after egg laying - 6.650-7.825 and 41.563-48.906 mg% and silkworm hemolymph - 6.920-6.980 and 43.250-43.625 mg%, respectively. The irradiation of eggs with 2.00 and 3,00 Gy gamma rays stimulated the increase of total nitrogen and protein content in silk gland by 6.66-7.3% compared to non-irradiated eggs of the same breed. 14 refs., 3 tabs. (author)

  16. Design and development of a content-based medical image retrieval system for spine vertebrae irregularity.

    Science.gov (United States)

    Mustapha, Aouache; Hussain, Aini; Samad, Salina Abdul; Zulkifley, Mohd Asyraf; Diyana Wan Zaki, Wan Mimi; Hamid, Hamzaini Abdul

    2015-01-16

    Content-based medical image retrieval (CBMIR) system enables medical practitioners to perform fast diagnosis through quantitative assessment of the visual information of various modalities. In this paper, a more robust CBMIR system that deals with both cervical and lumbar vertebrae irregularity is afforded. It comprises three main phases, namely modelling, indexing and retrieval of the vertebrae image. The main tasks in the modelling phase are to improve and enhance the visibility of the x-ray image for better segmentation results using active shape model (ASM). The segmented vertebral fractures are then characterized in the indexing phase using region-based fracture characterization (RB-FC) and contour-based fracture characterization (CB-FC). Upon a query, the characterized features are compared to the query image. Effectiveness of the retrieval phase is determined by its retrieval, thus, we propose an integration of the predictor model based cross validation neural network (PMCVNN) and similarity matching (SM) in this stage. The PMCVNN task is to identify the correct vertebral irregularity class through classification allowing the SM process to be more efficient. Retrieval performance between the proposed and the standard retrieval architectures are then compared using retrieval precision (Pr@M) and average group score (AGS) measures. Experimental results show that the new integrated retrieval architecture performs better than those of the standard CBMIR architecture with retrieval results of cervical (AGS > 87%) and lumbar (AGS > 82%) datasets. The proposed CBMIR architecture shows encouraging results with high Pr@M accuracy. As a result, images from the same visualization class are returned for further used by the medical personnel.

  17. Embedded or linked learning objects: Implications for content development, course design and classroom use

    Directory of Open Access Journals (Sweden)

    Gail Kopp

    2007-06-01

    Full Text Available This research explores the idea of embedding and linking to existing content in learning object repositories and investigates teacher-designer use of learning objects within one high school mathematics course in an online school. This qualitative case study supports and extends the learning object literature, and brings forward context-specific examples of issues around repository design, autonomy and self-containment, technical support and granularity. Moreover, these findings have implications for building learning objects and repositories that could better support teachers in their instructional design and pedagogical decision-making. Résumé : La présente recherche étudie la possibilité d’effectuer un emboîtement et d’établir des liens avec le contenu existant dans les référentiels sur les objets d’apprentissage et explore l’utilisation par les enseignants-concepteurs des objets d’apprentissage au sein d’un cours de mathématique du secondaire donné dans une école en ligne. Cette étude de cas qualitative appuie et vise la littérature sur les objets d’apprentissage et met en avant plan des exemples de questions touchant la conception de référentiels, l’autonomie et l’indépendance, le soutien technique et la granularité propres au contexte. De plus, ces conclusions ont des répercussions sur l’élaboration d’objets et de référentiels d’apprentissage qui pourraient mieux appuyer les enseignants dans le cadre de leur conception pédagogique et de leur prise de décision touchant l’enseignement.

  18. Health professionals as mobile content creators: teaching medical students to develop mHealth applications.

    Science.gov (United States)

    Masters, Ken

    2014-10-01

    Patient access to health information and patient-provider communication is integral to medicine, and can be facilitated by mobile applications ("apps"). Traditionally, student training in mobile Health (mHealth) has focussed on health professionals as consumers of information, with negative impacts on the quality and value of medical apps. This study focuses on teaching medical students to develop their own medical apps. At Sultan Qaboos University, Oman, an app development environment, iBuildApp, was taught to medical students and used to develop their first apps. Students were surveyed on their perceptions of the project. Of the 166 students, 107 (64.5%) completed the survey. There was an increase in the perceived need for such learning, apps were aimed primarily at patients, and previous programming experience was the strongest influencer of a positive experience. A majority (77.6%) wanted more sophisticated development environments in spite of their apparent struggles. The impact of previous experience is similar to other studies; the perceived value and focus on patient apps is indicative of an awareness of patients' use of the devices not reflected in all literature. It is possible to teach medical students the fundamentals of app design so that they may contribute to app development in the future.

  19. Face and content validation of a novel three-dimensional printed temporal bone for surgical skills development.

    Science.gov (United States)

    Da Cruz, M J; Francis, H W

    2015-07-01

    To assess the face and content validity of a novel synthetic, three-dimensional printed temporal bone for surgical skills development and training. A synthetic temporal bone was printed using composite materials and three-dimensional printing technology. Surgical trainees were asked to complete three structured temporal bone dissection exercises. Attitudes and impressions were then assessed using a semi-structured questionnaire. Previous cadaver and real operating experiences were used as a reference. Trainees' experiences of the synthetic temporal bone were analysed in terms of four domains: anatomical realism, usefulness as a training tool, task-based usefulness and overall reactions. Responses across all domains indicated a high degree of acceptance, suggesting that the three-dimensional printed temporal bone was a useful tool in skills development. A sophisticated three-dimensional printed temporal bone that demonstrates face and content validity was developed. The efficiency in cost savings coupled with low associated biohazards make it likely that the printed temporal bone will be incorporated into traditional temporal bone skills development programmes in the near future.

  20. Perl and Apache Your visual blueprint for developing dynamic Web content

    CERN Document Server

    McDaniel, Adam

    2010-01-01

    Visually explore the range of built-in and third-party libraries of Perl and Apache. Perl and Apache have been providing Common Gateway Interface (CGI) access to Web sites for 20 years and are constantly evolving to support the ever-changing demands of Internet users. With this book, you will heighten your knowledge and see how to usePerl and Apache to develop dynamic Web sites. Beginning with a clear, step-by-step explanation of how to install Perl and Apache on both Windows and Linux servers, you then move on to configuring each to securely provide CGI Services. CGI developer and author Adam

  1. 23 CFR 450.324 - Development and content of the transportation improvement program (TIP).

    Science.gov (United States)

    2010-04-01

    ... specified in sufficient detail (design concept and scope) for air quality analysis in accordance with the..., environment/NEPA, right-of-way, design, or construction), the following: (1) Sufficient descriptive material... principles and information, developed cooperatively by the MPO, State(s), and public transportation operator...

  2. Development of a Quantitative Tool to Assess the Content of Physical Therapy for Infants

    NARCIS (Netherlands)

    Blauw-Hospers, Cornill H.; Dirks, Tineke; Hulshof, Lily J.; Hadders-Algra, Mijna

    2010-01-01

    Purpose: The study aim was to describe and quantify physical therapy interventions for infants at high risk for developmental disorders. Methods: An observation protocol was developed based on knowledge about infant physical therapy and analysis of directly observable physiotherapeutic (PT) actions.

  3. Optimizing EFL Learners' Sensitizing Reading Skill: Development of Local Content-Based Textbook

    Science.gov (United States)

    Arifani, Yudhi

    2016-01-01

    The development of local wisdom based sensitizing reading material is aimed at penetrating one of the imperishable gaps between authentic and non-authentic reading materials dispute in an EFL teaching context. Promoting EFL learners' needs for the first semester students of English department at university level, who rarely or even never have a…

  4. The Development of Pedagogical Content Knowledge in First-Year Graduate Teaching Assistants

    Science.gov (United States)

    Judson, Thomas W.; Leingang, Matthew

    2016-01-01

    Our investigation is concerned with new teachers developing their ability to understand student thinking. We conducted individual interviews with graduate students teaching calculus for the first time, interviewing a representative sample of graduate students before and after their first teaching assignment. The interviews were transcribed and…

  5. The Digital Economy: Controversity of Content and Impact on Economic Development

    Directory of Open Access Journals (Sweden)

    Kolomiyets Ganna M.

    2017-07-01

    Full Text Available The transformations of the technological structure of current economy have led to the emergence of digital economy that offers significant opportunities and, at the same time, creates threats. The article is aimed at displaying methodological approaches to interpretation of digital economy, contradiction of the possible results of its development and functioning, and the practical relevance of research into this phenomenon. The digital economy transforms economic interactions; destroys long chains of intermediaries; speeds up the conclusion of different agreements; eliminates spatial constraints in access to markets; offers competitive advantages to companies regardless of their size; enables to create a scale effect and materialize its positive impact by reducing costs. At the same time, in developed countries and industry sectors that can easily be automated, the need for low-and medium-skill workers is severely reduced. A more part-time economy is being formed, with engagement of freelancers who are not covered by the social security system on a short-term basis. These processes threaten the stability of incomes and the development of the national economy. A comparative analysis of the development of digital economy uses the indices that can form the basis of the national economic foresight.

  6. A 10-Year Mechatronics Curriculum Development Initiative: Relevance, Content, and Results--Part I

    Science.gov (United States)

    Das, S.; Yost, S. A.; Krishnan, M.

    2010-01-01

    This paper describes the first phase of a Mechatronics Curriculum Development effort--the design of an "Introduction to Mechatronics" course, the infusion of mechatronics activities throughout the curriculum and in outreach activities, and assessment results. In addition, the relevance and impact of such a curriculum on the education of engineers…

  7. Wikis: Developing Pre-Service Teachers' Leadership Skills and Knowledge of Content Standards

    Science.gov (United States)

    Reid-Griffin, Angelia; Slaten, Kelli M.

    2016-01-01

    In this initial phase of our multi-year research study we set out to explore the development of leadership skills in our pre-service secondary teachers after using an online wiki, Wikispaces. This paper presents our methods for preparing a group of 13 mathematics and 3 science secondary pre-service teachers to demonstrate the essential knowledge,…

  8. Contemporary Development of Academic Reference Librarianship in the United States: A 44-Year Content Analysis

    Science.gov (United States)

    Wang, Hanrong; Tang, Yingqi; Knight, Carley

    2010-01-01

    This study analyzes job advertisements to identify the contemporary development of academic reference librarianship in the United States. Results show that more job openings, higher educational backgrounds, more duties & responsibilities, and variety of titles were assigned to academic reference librarian positions from 1966 through 2009.…

  9. The Process of Physics Teaching Assistants' Pedagogical Content Knowledge Development

    Science.gov (United States)

    Seung, Eulsun

    2013-01-01

    This study explored the process of physics teaching assistants' (TAs) PCK development in the context of teaching a new undergraduate introductory physics course. "Matter and Interactions" (M&I) has recently adopted a new introductory physics course that focuses on the application of a small number of fundamental physical…

  10. Development and testing of metallic fuels with high minor actinide content

    International Nuclear Information System (INIS)

    Meyer, M.K.; Hayes, S.L.; Kennedy, J.R.; Keiser, D.D.; Hilton, B.A.; Frank, S.M.; Kim, Y.-S.; Chang, G.; Ambrosek, R.G.

    2003-01-01

    Metallic alloys are promising candidates for use as fuels for transmutation and in advanced closed nuclear cycles. Metallic alloys have high heavy metal atom density, relatively high thermal conductivity, favorable gas release behavior, and lend themselves to remote recycle processes. Both non-fertile and uranium-bearing metal fuels containing minor actinide are under consideration for use as transmutation fuels by the U.S. Advanced Fuel Cycle (AFC) program, however, little irradiation performance data exists for fuel forms containing significant fractions of minor actinides. The first irradiation tests of non-fertile high-actinide-content fuels are scheduled to begin in early 2003 in the Advanced Test Reactor (ATR). The irradiation test matrix was designed to provide basic information on the irradiation behavior of binary Pu-Zr alloy fuel and the effect of the minor actinides americium and neptunium on alloy fuel behavior, together and separately. Five variants of transuranic containing zirconium-based alloy fuels are included in the AFC-1 irradiation test matrix. These are (in wt.%) Pu-40Zr, Pu-60Zr, Pu-12Am-40Zr, Pu-10Np-40Zr and Pu-10Np-10Am-40Zr. PuN-ZrN based fuels containing Am and Np are also included. All five of the fuel alloys have been fabricated in the form of cylindrical fuel slugs by arc-casting. Short melt times, on the order or 5-20 seconds, prevent the volatilization of significant quantities of americium metal, despite the high melt temperatures characteristic of the arc-melting process. Alloy microstructure have been characterized by x-ray diffraction and scanning electron microscopy. Thermal analysis has also been performed. The AFC-1 irradiation experiment configuration consists of twenty-four sodium bonded fuel specimens sealed in helium filled secondary capsules. The first capsule has a design burnup to 7 at.% 239 Pu; goal peak burnup of the second capsule is ∼18 at%. Capsule assemblies are placed within an aluminum flow-through basket

  11. Developing and evaluating a paper-and-pencil test to assess components of physics teachers' pedagogical content knowledge

    Science.gov (United States)

    Kirschner, Sophie; Borowski, Andreas; Fischer, Hans E.; Gess-Newsome, Julie; von Aufschnaiter, Claudia

    2016-05-01

    Teachers' professional knowledge is assumed to be a key variable for effective teaching. As teacher education has the goal to enhance professional knowledge of current and future teachers, this knowledge should be described and assessed. Nevertheless, only a limited number of studies quantitatively measures physics teachers' professional knowledge. The study reported in this paper was part of a bigger project with the broader goal of understanding teacher professional knowledge. We designed a test instrument to assess the professional knowledge of physics teachers (N = 186) in the dimensions of content knowledge (CK), pedagogical content knowledge (PCK), and pedagogical knowledge (PK). A model describing the relationships between these three dimensions of professional knowledge was created to inform the design of the tests used to measure CK, PCK, and PK. In this paper, we describe the model with particular emphasis on the PCK part, and the subsequent PCK test development and its implementation in detail. We report different approaches to evaluate the PCK test, including the description of content validity, the examination of the internal structure of professional knowledge, and the analysis of construct validity by testing teachers across different school subjects, teachers from different school types, pre-service teachers, and physicists. Our findings demonstrate that our PCK test results could distinguish physics teachers from the other groups tested. The PCK test results could not be explained by teachers' CK or PK, cognitive abilities, computational skills, or science knowledge.

  12. Development and content validation of a questionnaire to assess moral distress among social workers in long-term care facilities.

    Science.gov (United States)

    Lev, Sagit; Ayalon, Liat

    2018-03-01

    Despite the significance of ethical issues faced by social workers, research on moral distress among social workers has been extremely limited. The aim of the current study is to describe the development and content validation of a unique questionnaire to measure moral distress among social workers in long-term care facilities for older adults in Israel. The construction of the questionnaire was based on a secondary analysis of a qualitative study that addressed the moral dilemma of social workers in nursing homes in Israel. A content validation included review and evaluation by two experts, a cognitive interview with a nursing home social worker, and three focus groups of experts and the target population. The initial questionnaire consisted of 25 items. After the content validation process the questionnaire in its final version, consisted of 17 items and included two scales, measuring the frequency of morally loaded events and the intensity of distress that followed them. We believe that the questionnaire can contribute by broadening and deepening ethics discourse and research, with regard to social workers' obligation dilemmas and conflicts.

  13. The development of pedagogical content knowledge in science teachers: New opportunities through technology-mediated reflection and peer-exchange

    Science.gov (United States)

    Madeira, M. Cheryl-Ann

    This design-based research study investigates the development of pedagogical content knowledge among nine teacher-participants (N = 9) in three design phases. PCK is a particular type of teacher knowledge that addresses not only the teacher's understanding of the content to be instructed, but also ways of how to teach that content effectively. This knowledge has been well documented over several decades, and is seen as central to teacher expertise. However, its actual development has been difficult for researchers to investigate. This study offers a detailed perspective on how teachers developed PCK with their engagement in lesson planning and enactment of a project-based technology-enhanced lesson. The study includes two specific interventions designed to enhance teachers' development of PCK: (1) scaffolded reflection that occurs throughout the practices; and (2) peer-exchange of lesson plans, enactment ideas, and completed reflections. The findings demonstrate that teachers improve their planning and enactment of project-based technology-enhanced lessons with scaffolded reflection and peer exchange. Positive correlations were seen between teachers' engagement in the reflections and the quality of their lesson planning. Teachers who participated more deeply in the scaffolded reflections were able to understand how their lesson plans and enactment patterns fostered student understanding of relevant science concepts. Positive correlations were also seen between community influence and teacher lesson plans and enactment. Additionally, positive correlations were confirmed between teachers' level of participation in the peer exchange activities and the quality of their lesson planning and enactments. Teachers who contributed more deeply within the online and face-to-face peer community meetings benefited from the different perspectives of their peers about student learning and the best ways to succeed with project-based instruction. This study allowed some insight into

  14. Serum thyroid auto-antibody contents in GD patients developing hypothyroidism after 131I treatment

    International Nuclear Information System (INIS)

    Cao Huiling; Sun Lijuan; Ji Xiaopeng; Zhao Ming

    2004-01-01

    Objective: To explore the auto-immune factors predisposing to developing hypothyroidism after 131 I treatment in patients with Graves' disease (GD). Methods: Eighty-eight GD patients treated with 131 I were followed for three years. These patients were of two groups: Group A (n=35), serum TGA, TMA, TRAb all positive before treatment; Group B (n=53) serum TGA, TMA negative but TRAb positive. Results: In Group A, 31.40% (n=11) of all the patients were hypothyroid three years after treatment. The result was much better in Group B, with only 3.8% (n=2) being hypothyroid. The difference was significant. Conclusion: GD patients with positive TGA, TMA were liable to develop hypothyroidism after 131 I treatment. Those patients should be treated with lesser amount of the drug accordingly

  15. Microstructural and Texture Development in Two Austenitic Steels with High-Manganese Content

    DEFF Research Database (Denmark)

    Bhattacharya, Basudev; Ray, Ranjit Kumar; Leffers, Torben

    2015-01-01

    Two austenitic steels, Fe-21.3Mn-3.44Si-3.74Al-0.5C and Fe-29.8Mn-2.96Si-2.73Al-0.52C, were subjected to cold rolling with 30 to 80 pct reduction with an increment of 10 pct and subsequently the development of their microstructures and textures were studied. The overall texture after 80 pct cold ...

  16. Safety report content and development for test loop facility on MARIA reactor

    International Nuclear Information System (INIS)

    Konechko, A.; Shumskij, A.M.; Mikul'ahin, V.E.

    1982-01-01

    A 600 kW test loop facility for investigatin.o safety problems is realized on MARIA reactor in Poland together with USSR organizations. Safety reports have been developed in two steps at the designstage. The 1st report being essentially a preliminary safety analysis was developed within the scope of the feasibility study. At the engineering design stage the preliminary test loop facility safety report had been prepared considering measures excluding the possibility of the MARIA reactor damage. The test loop facility safety report is fulfilled for normal, transient and emergency operation regimes. Separate safety basing for each group of experiments will be prepared. The report presents the test loop facility safety criteria coordinated by the nuclear safety comission. They contains the preliminary reports on the test loop facility safety. At the final stage of construction and at thecommitioning stage the start-up safety report will be developed which after required correction and adding up the putting into operation data will turn into operation safety report [ru

  17. Patient experiences with oily skin: the qualitative development of content for two new patient reported outcome questionnaires.

    Science.gov (United States)

    Arbuckle, Robert; Atkinson, Mark J; Clark, Marci; Abetz, Linda; Lohs, Jan; Kuhagen, Ilka; Harness, Jane; Draelos, Zoe; Thiboutot, Diane; Blume-Peytavi, Ulrike; Copley-Merriman, Kati

    2008-10-16

    To develop the content for two new patient reported outcome (PRO) measures to: a) assess the severity of symptoms; and b) the impact of facial skin oiliness on emotional wellbeing using qualitative data from face to face, and internet focus groups in Germany and the US. Using input from initial treatment satisfaction focus groups (n = 42), a review of relevant literature and expert clinicians (n = 3), a discussion guide was developed to guide qualitative inquiry using Internet focus groups (IFGs). IFGs were conducted with German (n = 26) and US (n = 28) sufferers of oily skin. Questionnaire items were generated using coded transcript data from the focus groups. Cognitive debriefing was conducted online with 42 participants and face to face with an additional five participants to assess the comprehension of the items. There were equal numbers of male and female participants; mean age was 35.4 (SD 9.3) years. On average, participants had had oily skin for 15.2 years, and 74% (n = 40) reported having mild-moderate acne. Participants reported using visual, tactile and sensory (feel without touching their face) methods to evaluate the severity of facial oiliness. Oily facial skin had both an emotional and social impact, and was associated with feelings of unattractiveness, self-consciousness, embarrassment, irritation and frustration. Items were generated for a measure of oily skin severity (Oily Skin Self-Assessment Scale) and a measure of the impact of oily skin on emotional well-being (Oily Skin Impact Scale). Cognitive debriefing resulted in minor changes to the draft items and confirmed their face and content validity. The research provides insight into the experience of having oily skin and illustrates significant difficulties associated with the condition. Item content was developed for early versions of two PRO measures of the symptoms and emotional impact of oily facial skin. The psychometric validation of these measures reported elsewhere.

  18. Patient experiences with oily skin: The qualitative development of content for two new patient reported outcome questionnaires

    Directory of Open Access Journals (Sweden)

    Draelos Zoe

    2008-10-01

    Full Text Available Abstract Objective To develop the content for two new patient reported outcome (PRO measures to: a assess the severity of symptoms; and b the impact of facial skin oiliness on emotional wellbeing using qualitative data from face to face, and internet focus groups in Germany and the US. Methods Using input from initial treatment satisfaction focus groups (n = 42, a review of relevant literature and expert clinicians (n = 3, a discussion guide was developed to guide qualitative inquiry using Internet focus groups (IFGs. IFGs were conducted with German (n = 26 and US (n = 28 sufferers of oily skin. Questionnaire items were generated using coded transcript data from the focus groups. Cognitive debriefing was conducted online with 42 participants and face to face with an additional five participants to assess the comprehension of the items. Results There were equal numbers of male and female participants; mean age was 35.4 (SD 9.3 years. On average, participants had had oily skin for 15.2 years, and 74% (n = 40 reported having mild-moderate acne. Participants reported using visual, tactile and sensory (feel without touching their face methods to evaluate the severity of facial oiliness. Oily facial skin had both an emotional and social impact, and was associated with feelings of unattractiveness, self-consciousness, embarrassment, irritation and frustration. Items were generated for a measure of oily skin severity (Oily Skin Self-Assessment Scale and a measure of the impact of oily skin on emotional well-being (Oily Skin Impact Scale. Cognitive debriefing resulted in minor changes to the draft items and confirmed their face and content validity. Conclusion The research provides insight into the experience of having oily skin and illustrates significant difficulties associated with the condition. Item content was developed for early versions of two PRO measures of the symptoms and emotional impact of oily facial skin. The psychometric validation of

  19. Evaluating the content and development of decision aid tools for the management of menopause: A scoping review.

    Science.gov (United States)

    Siyam, Tasneem; Sultani, Humirah; Ross, Sue; Chatterley, Trish; Yuksel, Nese

    2017-12-01

    Decision-making during menopause (especially surgical menopause) can be complex given the variability in risk-benefit perceptions of menopausal treatments. Decision aid tools (DATs) help women participate in decision-making about options. Our objective is to identify and evaluate the content and development of DATs for managing menopause, with a special focus on surgical menopause. We systematically searched electronic databases, including MEDLINE and EMBASE, from inception to March 2017 for relevant records. The principal inclusion criterion was that papers reported studies on DATs for managing menopause. Search terms were derived from two concepts: menopause and DATs. Data extracted were presented in written evidence tables and narrative summaries. Our search yielded 18,801 records. Of these, 26 records met our inclusion criteria, which gave rise to 12 DATs from peer-reviewed literature and 6 from grey literature. Seventeen DATs were focused on natural menopause and two targeted surgical menopause, both identified from grey literature. More than half were published before the Women's Health Initiative (WHI) publication and 70% before the release of the International Patient Decision Aid Standards (IPDAS). Very few studies reported the full development of the DAT involved, and less than half of DATs were informed by a needs assessment to identify the decisional needs of their target population. Most DATs focused on hormone therapy as a treatment option and did not provide a comprehensive overview of other options. None of the DATs reported the steps involved in finding, appraising and summarizing scientific content of the tool. This review highlights several limitations in the content and development of DATs for managing menopause. No peer-reviewed DATs were identified for surgical menopause. A need for a complete, evidence-based DAT in the context of surgical menopause is identified. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Development and content validation of a patient-reported endometriosis pain daily diary.

    Science.gov (United States)

    van Nooten, Floortje E; Cline, Jennifer; Elash, Celeste A; Paty, Jean; Reaney, Matthew

    2018-01-04

    Endometriosis is a common gynecological disorder that causes inflammation and pelvic pain. Endometriosis-related pain is best captured with patient-reported outcome (PRO) measures, however, assessment of endometriosis-related pain in clinical trials has been difficult in the absence of a reliable and valid PRO instrument. We describe the development of the Endometriosis Pain Daily Diary (EPDD), an electronic PRO developed as a survey instrument to assess endometriosis-related pain and its impact on patients' lives. The EPDD was initially developed on the basis of an existing Endometriosis Pain and Bleeding Diary, a targeted review of relevant literature, clinical expert interviews, and open-ended (concept elicitation) patient interviews in the United States (US) and Japan which captured patients' experience with endometriosis. Cognitive interviews of patients with endometriosis were conducted to evaluate patient comprehension of the EPDD items. A conceptual model of endometriosis was developed, and meetings with US and European regulatory authorities provided feedback for validating the EPDD in the context of clinical trials. Translatability assessments of the EPDD were conducted to confirm its appropriate interpretation and ease of completion across 17 languages. The iterative development progressed through three versions of the instrument. The EPDDv1 included 18 items relating to dysmenorrhea/pelvic pain, dyspareunia and sexual activity, bleeding, hot flashes, daily activities, and use of rescue medication. The EPDDv2 was a larger 43-item survey tested in cognitive interviews and subsequently revised to yield the current 11-item EPDDv3, consisting of five core items relating to dysmenorrhea, non-menstrual pelvic pain, and dyspareunia, and six extension items relating to sexual activity, daily activities, and use of rescue medication. The EPDD is a PRO for the evaluation of endometriosis-related pain and its associated impacts on patients' lives. The EPDD

  1. Using Structured Observation and Content Analysis to Explore the Presence of Older People in Public Fora in Developing Countries

    Directory of Open Access Journals (Sweden)

    Geraldine Nosowska

    2014-01-01

    Full Text Available There is a lack of research on the everyday lives of older people in developing countries. This exploratory study used structured observation and content analysis to examine the presence of older people in public fora and considered the methods’ potential for understanding older people’s social integration and inclusion. Structured observation occurred of public social spaces in six cities each located in a different developing country and in one city in the United Kingdom, together with content analysis of the presence of people in newspaper pictures and on television in the selected countries. Results indicated that across all fieldwork sites and data sources, there was a low presence of older people, with women considerably less present than men in developing countries. There was variation across fieldwork sites in older people’s presence by place and time of day and in their accompanied status. The presence of older people in images drawn from newspapers was associated with the news/non-news nature of the source. The utility of the study’s methodological approach is considered, as is the degree to which the presence of older people in public fora might relate to social integration and inclusion in different cultural contexts.

  2. Development and use of a content search strategy for retrieving studies on patients' views and preferences.

    Science.gov (United States)

    Selva, Anna; Solà, Ivan; Zhang, Yuan; Pardo-Hernandez, Hector; Haynes, R Brian; Martínez García, Laura; Navarro, Tamara; Schünemann, Holger; Alonso-Coello, Pablo

    2017-08-30

    Identifying scientific literature addressing patients' views and preferences is complex due to the wide range of studies that can be informative and the poor indexing of this evidence. Given the lack of guidance we developed a search strategy to retrieve this type of evidence. We assembled an initial list of terms from several sources, including the revision of the terms and indexing of topic-related studies and, methods research literature, and other relevant projects and systematic reviews. We used the relative recall approach, evaluating the capacity of the designed search strategy for retrieving studies included in relevant systematic reviews for the topic. We implemented in practice the final version of the search strategy for conducting systematic reviews and guidelines, and calculated search's precision and the number of references needed to read (NNR). We assembled an initial version of the search strategy, which had a relative recall of 87.4% (yield of 132/out of 151 studies). We then added some additional terms from the studies not initially identified, and re-tested this improved version against the studies included in a new set of systematic reviews, reaching a relative recall of 85.8% (151/out of 176 studies, 95% CI 79.9 to 90.2). This final version of the strategy includes two sets of terms related with two domains: "Patient Preferences and Decision Making" and "Health State Utilities Values". When we used the search strategy for the development of systematic reviews and clinical guidelines we obtained low precision values (ranging from 2% to 5%), and the NNR from 20 to 50. This search strategy fills an important research gap in this field. It will help systematic reviewers, clinical guideline developers, and policy-makers to retrieve published research on patients' views and preferences. In turn, this will facilitate the inclusion of this critical aspect when formulating heath care decisions, including recommendations.

  3. Development of CYPRUS+ with Fracture information, Groundwater chemistry contents and PID modules

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Hyun; Hwang, Yong Soo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Han, Jae Jun [Korea University, Seoul (Korea, Republic of)

    2009-05-15

    Cyprus is the CYber R and D Platform for a Radwaste disposal in a Underground System, Developed by KAERI since 2000. An automated quality assurance system designed to ensure all project members follow the compulsory QA procedures from the first to the last stage of a TSPA. Cyprus is focused on how documents are written and stored. For these reasons Cyprus is made using PHP web programming language which is easy to handle and available to distribute freely. So a researcher can use this program anywhere, anytime.

  4. Analyzing user-generated online content for drug discovery: development and use of MedCrawler.

    Science.gov (United States)

    Helfenstein, Andreas; Tammela, Päivi

    2017-04-15

    Ethnopharmacology, or the scientific validation of traditional medicine, is a respected starting point in drug discovery. Home remedies and traditional use of plants are still widespread, also in Western societies. Instead of perusing ancient pharmacopeias, we developed MedCrawler, which we used to analyze blog posts for mentions of home remedies and their applications. This method is free and accessible from the office computer. We developed MedCrawler, a data mining tool for analyzing user-generated blog posts aiming to find modern 'traditional' medicine or home remedies. It searches user-generated blog posts and analyzes them for correlations between medically relevant terms. We also present examples and show that this method is capable of delivering both scientifically validated uses as well as not so well documented applications, which might serve as a starting point for follow-up research. Source code is available on GitHub at {{ https://github.com/a-hel/medcrawler }}. paivi.tammela@helsinki.fi. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  5. Developing a theory driven text messaging intervention for addiction care with user driven content.

    Science.gov (United States)

    Muench, Frederick; Weiss, Rebecca A; Kuerbis, Alexis; Morgenstern, Jon

    2013-03-01

    The number of text messaging interventions designed to initiate and support behavioral health changes have been steadily increasing over the past 5 years. Messaging interventions can be tailored and adapted to an individual's needs in their natural environment-fostering just-in-time therapies and making them a logical intervention for addiction continuing care. This study assessed the acceptability of using text messaging for substance abuse continuing care and the intervention preferences of individuals in substance abuse treatment in order to develop an interactive mobile text messaging intervention. Fifty individuals enrolled in intensive outpatient substance abuse treatment completed an assessment battery relating to preferred logistics of mobile interventions, behavior change strategies, and types of messages they thought would be most helpful to them at different time points. Results indicated that 98% participants were potentially interested in using text messaging as a continuing care strategy. Participants wrote different types of messages that they perceived might be most helpful, based on various hypothetical situations often encountered during the recovery process. Although individuals tended to prefer benefit driven over consequence driven messages, differences in the perceived benefits of change among individuals predicted message preference. Implications for the development of mobile messaging interventions for the addictions are discussed. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  6. The effect of clay content in sands used for cementitious materials in developing countries

    International Nuclear Information System (INIS)

    Fernandes, V.A.; Purnell, P.; Still, G.T.; Thomas, T.H.

    2007-01-01

    The cost of building materials in Less Economically Developed Countries (LEDCs) is one of the single largest contributing factors to housing costs. They are often transported over relatively large distances at considerable expense. Local sands may contain significant amounts of clay, considered by local artisans to be detrimental to concrete strength; however, in an LEDC context, there is little evidence to support this. In this study, the compressive strength and workability of representative LEDC clay-contaminated concrete was determined. Clay-cement interactions were studied using X-Ray Diffraction (XRD). Different clays appeared to have fundamentally different effects on both workability and strength. No chemical interactions were detected. It was concluded that satisfactory concrete could be made from clay-contaminated sand

  7. Development of a quantitative tool to assess the content of physical therapy for infants.

    Science.gov (United States)

    Blauw-Hospers, Cornill H; Dirks, Tineke; Hulshof, Lily J; Hadders-Algra, Mijna

    2010-01-01

    The study aim was to describe and quantify physical therapy interventions for infants at high risk for developmental disorders. An observation protocol was developed based on knowledge about infant physical therapy and analysis of directly observable physiotherapeutic (PT) actions. The protocol's psychometric quality was assessed. Videos of 42 infant physical therapy sessions at 4 or 6 months of corrected age were analyzed. The observation protocol classified PT actions into 8 mutually exclusive categories. Virtually all PT actions during treatment could be classified. Inter- and intrarater agreements were satisfactory (intraclass correlations, 0.68-1.00). Approximately 40% of treatment time was spent challenging the infant to produce motor behavior by themselves, whereas approximately 30% of time facilitation techniques were applied. Tradition-based sessions could be differentiated from function-oriented ones. It is possible to document PT actions during physical therapy treatment of infants at high risk for cerebral palsy in a systematic, standardized, and reliable way.

  8. Development of the New Educational Content "small Uas in Civil Engineering Application Scenarios"

    Science.gov (United States)

    Levin, E.; Vach, K.; Shults, R.

    2017-12-01

    The key point of this paper is presentation of the main idea and some results of the project "Small UAS in civil engineering application scenarios" (SUAS-CAS). This project was proposed by newly established in 2016 ISPRS WG V/7: "Innovative Technologies in Training Civil Engineers and Architects". Here we are presenting our experience in using low-cost UAS in training architects at Kyiv National University of Construction and Architecture, which was chosen as basic for this project. In the first part of paper, the project outline is presented. Then the first and possible follow project outcomes were described. In some details is described the training module "Small UAS in architecture" which was developed and included as a part of the subject "Architectural photogrammetry".

  9. Development of the charcoal adsorption technique for determination of radon content in natural gas

    International Nuclear Information System (INIS)

    Paewpanchon, P.; Chanyotha, S.

    2017-01-01

    A technique for the determination of the radon concentration in natural gas using charcoal adsorption has been developed to study the effects of parameters that influence the adsorption efficiency of radon onto activated charcoal. Several sets of experiments were conducted both in the laboratory and in an actual natural gas field for comparison. The results show that the adsorption capability of radon onto activated charcoal varies inversely with temperature, hydrocarbon concentration and the humidity contained within the natural gas. A technique utilizing dry ice as a coolant was found to be the most effective for trapping radon in natural gas samples at the production site. A desiccant can be used to remove moisture from the sampling gas. The technique described here increases the adsorption efficiency of activated charcoal by 10-20% compared to our previous study. (authors)

  10. DEVELOPMENT OF THE CHARCOAL ADSORPTION TECHNIQUE FOR DETERMINATION OF RADON CONTENT IN NATURAL GAS.

    Science.gov (United States)

    Paewpanchon, P; Chanyotha, S

    2017-11-01

    A technique for the determination of the radon concentration in natural gas using charcoal adsorption has been developed to study the effects of parameters that influence the adsorption efficiency of radon onto activated charcoal. Several sets of experiments were conducted both in the laboratory and in an actual natural gas field for comparison. The results show that the adsorption capability of radon onto activated charcoal varies inversely with temperature, hydrocarbon concentration and the humidity contained within the natural gas. A technique utilizing dry ice as a coolant was found to be the most effective for trapping radon in natural gas samples at the production site. A desiccant can be used to remove moisture from the sampling gas. The technique described here increases the adsorption efficiency of activated charcoal by 10-20% compared to our previous study. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Using Multiple Lenses to Examine the Development of Beginning Biology Teachers' Pedagogical Content Knowledge for Teaching Natural Selection Simulations

    Science.gov (United States)

    Sickel, Aaron J.; Friedrichsen, Patricia

    2018-02-01

    Pedagogical content knowledge (PCK) has become a useful construct to examine science teacher learning. Yet, researchers conceptualize PCK development in different ways. The purpose of this longitudinal study was to use three analytic lenses to understand the development of three beginning biology teachers' PCK for teaching natural selection simulations. We observed three early-career biology teachers as they taught natural selection in their respective school contexts over two consecutive years. Data consisted of six interviews with each participant. Using the PCK model developed by Magnusson et al. (1999), we examined topic-specific PCK development utilizing three different lenses: (1) expansion of knowledge within an individual knowledge base, (2) integration of knowledge across knowledge bases, and (3) knowledge that explicitly addressed core concepts of natural selection. We found commonalities across the participants, yet each lens was also useful to understand the influence of different factors (e.g., orientation, subject matter preparation, and the idiosyncratic nature of teacher knowledge) on PCK development. This multi-angle approach provides implications for considering the quality of beginning science teachers' knowledge and future research on PCK development. We conclude with an argument that explicitly communicating lenses used to understand PCK development will help the research community compare analytic approaches and better understand the nature of science teacher learning.

  12. Selected element contents formation in linseed plants (Linum usitatissimum L. depending on the phase of development and plant part

    Directory of Open Access Journals (Sweden)

    Tadeusz Zając

    2013-12-01

    Full Text Available A single factor (variety strict field experiment was carried out in 1999-2000 at the experimental station of the Department of Plant Production, Agricultural University of Krakow located at Prusy near Cracow to study the changes in selected macro-and microelement concentrations in the top parts of linseed and the uptake of these elements during vegetation at the characteristic phases of development, including also the plant parts, i.e. leaves, stems, seeds and straw. On the basis of obtained results it was demonstrated that microelement contents in the linseed top parts changed considerably with the plant growth. The levels of Cr, Zn,Cd, Fe and Mn were highest at budding, while Cr, Pb, Fe and Mn levels were lowest at full maturity phase. Linseed grown in the area unpolluted with trace elements did not reveal the ability to accumulate excessive amounts of Cr, Zn, Pb, Cu, Ni, Fe and Mn, undesired from the usefulness for consumption point of view. Cadmium, irrespective of the examined stage of plant development, revealed high capacity for an excessive accumulation in the top parts. The contents and reciprocal ratios of macroelements in plants changed variously with their growth. The highest Na and K contents were noticed at budding phase, Ca at vegetative stage (arborescent and Mg at the initial budding. The widest Ca:P ratio and K:(Ca+Mg ratio occurred at budding, whereas K:Na ratio at full maturity phase. Linseed accumulated macro- and microele ments in the yield at various rates. Among the analysed elements Cd, Zn and Ni were taken up proportionally to increasing yields of linseed top part biomass.

  13. CCP4 Software Suite: history, evolution, content, challenges and future developments

    Directory of Open Access Journals (Sweden)

    Krissinel, Eugene

    2015-04-01

    Full Text Available Collaborative Computational Project Number 4 (CCP4 in Protein Crystallography is a public resource for producing and supporting a world-leading, integrated Suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques. CCP4 supports the widest possible researcher community, embracing academic, not for profit, and for profit research. The primary aims of CCP4 include development and support of the development of cutting edge approaches to experimental determination and analysis of protein structure, with integration of them into the suite for worldwide dissemination. In addition, CCP4 plays an important role in the education and training of scientists in experimental structural biology. In this paper, we overview CCP4’s 35-year long history and (technical milestones of its evolution. We will also consider how a particular structure of CCP4 Suite and Collaboration has emerged, its main functionality, current state and plans for future.“Collaborative Computational Project Number 4 (CCP4” en Cristalografía de Proteínas es un recurso público líder mundial, encaminado a producir y mantener un conjunto integrado de programas que permite a los investigadores determinar estructuras macromoleculares mediante cristalografía de rayos-X, así como por otras técnicas biofísicas. CCP4 va dirigido a la más amplia comunidad científica posible, abarcando investigaciones en el ámbito académico, tanto sin ánimo de lucro como con él. Sus objetivos principales incluyen el desarrollo y soporte de metodologías punteras para la determinación y análisis de estructuras de proteínas, integradas en un conjunto bien definido para facilitar su fácil difusión mundial. Además, CCP4 juega un papel importante en la formación y entrenamiento de científicos en biología estructural experimental. En este artículo, ofreceré una visión de conjunto de la larga historia e hitos t

  14. Professional Development for Researchers in Solid Earth Science Evolved to Include Scientific and Educational Content

    Science.gov (United States)

    Eriksson, S. C.; Arrowsmith, R.; Olds, S. E.

    2011-12-01

    Integrated measures of crustal deformation provide valuable insight about tectonic and human-induced processes for scientists and educators alike. UNAVCO in conjunction with EarthScope initiated a series of short courses for researchers to learn the processing and interpretation of data from new technologies such as high precision GPS, Strainmeter, InSar and LiDAR that provide deformation information relevant to many geoscience sub-disciplines. Intensive short courses of a few days and the widespread availability of processed data through large projects such as EarthScope and GEON enable more geoscientists to incorporate these data into diverse projects. Characteristics of the UNAVCO Short Course Series, reaching over 400 participants since 2005, include having short course faculty who have pioneered development of each technology; open web-access to course materials; processing software installed on class-ready computers; no course fees; scholarships for students, post-doctoral fellows, and emerging faculty when needed; formative evaluation of the courses; community-based decisions on topics; and recruitment of participants across relevant geoscience disciplines. In 2009, when EarthScope airborne LiDAR data became available to the public through OpenTopographhy, teaching materials were provided to these researchers to incorporate the latest technologies into teaching. Multiple data sets across technologies have been developed with instructions on how to access the various data sets and incorporate them into geological problem sets. Courses in GPS, airborne LiDAR, strainmeter, and InSAR concentrate on data processing with examples of various geoscience applications. Ground-based LiDAR courses also include data acquisition. Google Earth is used to integrate various forms of data in educational applications. Various types of EarthScope data can now be used by a variety of geoscientists, and the number of scientists who have the skills and tools to use these various

  15. Development of techniques for measuring plutonium contents in TRU wastes by NDA methods

    International Nuclear Information System (INIS)

    Matsubayashi, Toshiyuki; Kuwana, Katsumi; Morita, Tomio; Izuhara, Shigeomi; Suzuki, Masahiro

    1983-01-01

    In order to develop a technique for measuring the amount of plutonium in plutonium-contaminated (TRU) wastes, a passive gamma method was selected from many candidate methods, and examined for the suitability by applying the method to low density wastes. A segmented gamma scanner was used for the experiment. The instrument is composed mainly of a Ge(Li) detector, multichannel analyser, data processing system, turntable and transmission radiation source of (75)Se. A sham waste was prepared by adding plutonium oxide powder as a radiation source to waste matrix in a 20-1 carton box. The sham waste was put on the turntable, and the detector was set at 50 cm distance from the center of the turntable. 414 keV gamma ray emitted from (239)Pu was utilized for the assay of plutonium in the experiment. The effects of combustible (paper) waste matrix, organic chlorinated material matrix, and the distribution of plutonium source in a box on the count rate were examined, and it was concluded that 1) about 10 mg of (239)Pu contained in both matrices should be assayed by the passive gamma method, 2) 50 mg of (239) Pu was measured at 30 % confidence level with 2000 sec measuring time, 3) the effect of distribution of plutonium in a waste was able to be reduced to a value of less than 15 % by rotating the waste on the turntable. (Yoshitake, I.)

  16. Developing effective messages about potable recycled water: The importance of message structure and content

    Science.gov (United States)

    Price, J.; Fielding, K. S.; Gardner, J.; Leviston, Z.; Green, M.

    2015-04-01

    Community opposition is a barrier to potable recycled water schemes. Effective communication strategies about such schemes are needed. Drawing on social psychological literature, two experimental studies are presented, which explore messages that improve public perceptions of potable recycled water. The Elaboration-Likelihood Model of information processing and attitude change is tested and supported. Study 1 (N = 415) premeasured support for recycled water, and trust in government information at Time 1. Messages varied in complexity and sidedness were presented at Time 2 (3 weeks later), and support and trust were remeasured. Support increased after receiving information, provided that participants received complex rather than simple information. Trust in government was also higher after receiving information. There was tentative evidence of this in response to two-sided messages rather than one-sided messages. Initial attitudes to recycled water moderated responses to information. Those initially neutral or ambivalent responded differently to simple and one-sided messages, compared to participants with positive or negative attitudes. Study 2 (N = 957) tested the effectiveness of information about the low relative risks, and/or benefits of potable recycled water, compared to control groups. Messages about the low risks resulted in higher support when the issue of recycled water was relevant. Messages about benefits resulted in higher perceived issue relevance, but did not translate into greater support. The results highlight the importance of understanding people's motivation to process information, and need to tailor communication to match attitudes and stage of recycled water schemes' development.

  17. Measuring what matters to patients: Using goal content to inform measure choice and development.

    Science.gov (United States)

    Jacob, Jenna; Edbrooke-Childs, Julian; Law, Duncan; Wolpert, Miranda

    2017-04-01

    Personalised care requires personalised outcomes and ways of feeding back clinically useful information to clinicians and practitioners, but it is not clear how to best personalise outcome measurement and feedback using existing standardised outcome measures. The constant comparison method of grounded theory was used to compare goal themes derived from goals set at the outset of therapy for 180 children aged between 4 and 17 years, visiting eight child and adolescent mental health services, to existing standardised outcome measures used as part of common national datasets. In all, 20 out of 27 goal themes corresponded to items on at least one commonly used outcome measure. Consideration of goal themes helped to identify potential relevant outcome measures. However, there were several goal themes that were not captured by items on standardised outcome measures. These seemed to be related to existential factors such as understanding, thinking about oneself and future planning. This presents a powerful framework for how clinicians can use goals to help select a standardised outcome measure (where this is helpful) in addition to the use of a goal-based outcome measure and personalise choices. There may be areas not captured by standardised outcome measures that may be important for children and young people and which may only be currently captured in goal measurement. There is an indication that we may not be measuring what is important to children and young people. We may need to develop or look for new measures that capture these areas.

  18. EFL oral skills behaviour when implementing blended learning in a content-subject teachers’ professional development course

    Directory of Open Access Journals (Sweden)

    Natalia Sanchez Narvaez

    2017-08-01

    Full Text Available The increasing use of technology in educational settings (Murray, 2014; Zandi, Thang, & Krish, 2014 encourages teachers to refocus their professional development by centering their efforts on becoming proficient in the use of information and communication technologies (ICTs in language lessons (Chen, Chen, & Tsai, 2009. As such, this qualitative action research project intended to describe content-subject teachers’ EFL oral behavior when blended learning was implemented in a professional development course and to determine the influence of blended learning in EFL oral skill behavior. The participants were seven content-subject teachers from a private school in Huila, Colombia. Data were gathered via in-depth interviews, class observations, video recording analysis, teachers’ reflection, students’ artifacts, and a survey. Data were collected during the implementation of an English blended course in which 12 lessons were divided into six face-to-face sessions and six online meetings. The findings suggest that EFL oral skill behavior is connected with use of vocabulary, use of body language, pronunciation and intonation patterns, production of chunks of language, monitoring oral production and, motivation and engagement. In addition, blended learning influenced participants’ oral production.

  19. Investigating the Impact of NGSS-Aligned Professional Development on PreK-3 Teachers' Science Content Knowledge and Pedagogy

    Science.gov (United States)

    Tuttle, Nicole; Kaderavek, Joan N.; Molitor, Scott; Czerniak, Charlene M.; Johnson-Whitt, Eugenia; Bloomquist, Debra; Namatovu, Winnifred; Wilson, Grant

    2016-11-01

    This pilot study investigates the impact of a 2-week professional development Summer Institute on PK-3 teachers' knowledge and practices. This Summer Institute is a component of [program], a large-scale early-childhood science project that aims to transform PK-3 science teaching. The mixed-methods study examined concept maps, lesson plans, and classroom observations to measure possible changes in PK-3 teachers' science content knowledge and classroom practice from 11 teachers who attended the 2014 Summer Institute. Analysis of the concept maps demonstrated statistically significant growth in teachers' science content knowledge. Analysis of teachers' lesson plans demonstrated that the teachers could design high quality science inquiry lessons aligned to the Next Generation Science Standards following the professional development. Finally, examination of teachers' pre- and post-Summer Institute videotaped inquiry lessons showed evidence that teachers were incorporating new inquiry practices into their teaching, especially regarding classroom discourse. Our results suggest that an immersive inquiry experience is effective at beginning a shift towards reform-aligned science and engineering instruction but that early elementary educators require additional support for full mastery.

  20. Development, content validity and test-retest reliability of the Lifelong Physical Activity Skills Battery in adolescents.

    Science.gov (United States)

    Hulteen, Ryan M; Barnett, Lisa M; Morgan, Philip J; Robinson, Leah E; Barton, Christian J; Wrotniak, Brian H; Lubans, David R

    2018-03-28

    Numerous skill batteries assess fundamental motor skill (e.g., kick, hop) competence. Few skill batteries examine lifelong physical activity skill competence (e.g., resistance training). This study aimed to develop and assess the content validity, test-retest and inter-rater reliability of the "Lifelong Physical Activity Skills Battery". Development of the skill battery occurred in three stages: i) systematic reviews of lifelong physical activity participation rates and existing motor skill assessment tools, ii) practitioner consultation and iii) research expert consultation. The final battery included eight skills: grapevine, golf swing, jog, push-up, squat, tennis forehand, upward dog and warrior I. Adolescents (28 boys, 29 girls; M = 15.8 years, SD = 0.4 years) completed the Lifelong Physical Activity Skills Battery on two occasions two weeks apart. The skill battery was highly reliable (ICC = 0.84, 95% CI = 0.72-0.90) with individual skill reliability scores ranging from moderate (warrior I; ICC = 0.56) to high (tennis forehand; ICC = 0.82). Typical error (4.0; 95% CI 3.4-5.0) and proportional bias (r = -0.21, p = .323) were low. This study has provided preliminary evidence for the content validity and reliability of the Lifelong Physical Activity Skills Battery in an adolescent population.

  1. Development of Criteria for Flameholding Tendencies within Premixer Passages for High Hydrogen Content Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Elliot Sullivan- [Univ. of California, Irvine, CA (United States); McDonell, Vincent G. [Univ. of California, Irvine, CA (United States)

    2014-12-01

    Due to increasingly stringent air quality requirements stationary power gas turbines have moved to lean-premixed operation, which reduces pollutant emissions but can result in flashback. Flashback can cause serious damage to the premixer hardware. Curtailing flashback can be difficult with hydrocarbon fuels and becomes even more challenging when hydrogen is used as the fuel. The two main approaches for coping with flashback are either to design a combustor that is resistant to flashback, or to design a premixer that will not anchor a flame if flashback occurs. Even with a well-designed combustor flashback can occur under certain circumstances, thus it is necessary to determine how to avoid flameholding within the premixer passageways of a gas turbine. To this end, an experiment was designed that would determine the flameholding propensities at elevated pressures and temperatures of three different classes of geometric features commonly found in gas turbine premixers, with both natural gas and hydrogen fuel. Experiments to find the equivalence ratio at blow off were conducted within an optically accessible test apparatus with four flameholders: 0.25 and 0.50 inch diameter cylinders, a reverse facing step with a height of 0.25 inches, and a symmetric airfoil with a thickness of 0.25 inches and a chord length of one inch. Tests were carried out at temperatures between 300 K and 750 K, at pressures up to 9 atmospheres. Typical bulk velocities were between 40 and 100 m/s. The effect of airfoil’s angle of rotation was also investigated. Blow off for hydrogen flames was found to occur at much lower adiabatic flame temperatures than natural gas flames. Additionally it was observed that at high pressures and high turbulence intensities, reactant velocity does not have a noticeable effect on the point of blow off due in large part to corresponding increases in turbulent flame speed. Finally a semi empirical correlation was developed that predicts flame extinction for both

  2. Effects of Light Intensity on Development and Chlorophyll Content in the Arabidopsis Mutant Plants with Defects in Photosynthesis

    Directory of Open Access Journals (Sweden)

    E.Yu. Garnik

    2015-12-01

    Full Text Available The developmental stages and adaptability to different light intensity (150 µmol*m-2*s-1 and 100 µmol*m-2*s-1 in Arabidopsis mutant lines with defects of photosynthetic apparatus were analyzed. Plant development in the mutant lines depended on the light intensity to varying degrees. Lines ch1-1 (lack of the chlorophyllide a oxygenase and rtn16 (decreased chlorophyll a and b amounts were the most susceptible to the light decrease. No one of the investigated lines demonstrated chlorophyll a/b rate alteration under the different light conditions. The depleted chlorophyll content has had the major effect on the mutant plants development under the different light conditions. The different chlorophyll a/b rate correlated with the different adaptability of mutant plants to low light.

  3. Development and validation of climate change system thinking instrument (CCSTI) for measuring system thinking on climate change content

    Science.gov (United States)

    Meilinda; Rustaman, N. Y.; Firman, H.; Tjasyono, B.

    2018-05-01

    The Climate Change System Thinking Instrument (CCSTI) is developed to measure a system thinking ability in the concept of climate change. CCSTI is developed in four phase’s development including instrument draft development, validation and evaluation including readable material test, expert validation, and field test. The result of field test is analyzed by looking at the readability score in Cronbach’s alpha test. Draft instrument is tested on college students majoring in Biology Education, Physics Education, and Chemistry Education randomly with a total number of 80 college students. Score of Content Validation Index at 0.86, which means that the CCSTI developed are categorized as very appropriate with question indicators and Cronbach’s alpha about 0.605 which mean categorized undesirable to minimal acceptable. From 45 questions of system thinking, there are 37 valid questions spread in four indicators of system thinking, which are system thinking phase I (pre-requirement), system thinking phase II (basic), system thinking phase III (intermediate), and system thinking phase IV (coherent expert).

  4. The Development of Narrative Productivity, Syntactic Complexity, Referential Cohesion and Event Content in Four- to Eight-Year-Old Finnish Children

    Science.gov (United States)

    Mäkinen, Leena; Loukusa, Soile; Nieminen, Lea; Leinonen, Eeva; Kunnari, Sari

    2014-01-01

    This study focuses on the development of narrative structure and the relationship between narrative productivity and event content. A total of 172 Finnish children aged between four and eight participated. Their picture-elicited narrations were analysed for productivity, syntactic complexity, referential cohesion and event content. Each measure…

  5. Development of new analytical methods for the determination of caffeine content in aqueous solution of green coffee beans.

    Science.gov (United States)

    Weldegebreal, Blen; Redi-Abshiro, Mesfin; Chandravanshi, Bhagwan Singh

    2017-12-05

    This study was conducted to develop fast and cost effective methods for the determination of caffeine in green coffee beans. In the present work direct determination of caffeine in aqueous solution of green coffee bean was performed using FT-IR-ATR and fluorescence spectrophotometry. Caffeine was also directly determined in dimethylformamide solution using NIR spectroscopy with univariate calibration technique. The percentage of caffeine for the same sample of green coffee beans was determined using the three newly developed methods. The caffeine content of the green coffee beans was found to be 1.52 ± 0.09 (% w/w) using FT-IR-ATR, 1.50 ± 0.14 (% w/w) using NIR and 1.50 ± 0.05 (% w/w) using fluorescence spectroscopy. The means of the three methods were compared by applying one way analysis of variance and at p = 0.05 significance level the means were not significantly different. The percentage of caffeine in the same sample of green coffee bean was also determined by using the literature reported UV/Vis spectrophotometric method for comparison and found to be 1.40 ± 0.02 (% w/w). New simple, rapid and inexpensive methods were developed for direct determination of caffeine content in aqueous solution of green coffee beans using FT-IR-ATR and fluorescence spectrophotometries. NIR spectrophotometry can also be used as alternative choice of caffeine determination using reduced amount of organic solvent (dimethylformamide) and univariate calibration technique. These analytical methods may therefore, be recommended for the rapid, simple, safe and cost effective determination of caffeine in green coffee beans.

  6. Development and in house validation of a new thermogravimetric method for water content analysis in soft brown sugar.

    Science.gov (United States)

    Ducat, Giseli; Felsner, Maria L; da Costa Neto, Pedro R; Quináia, Sueli P

    2015-06-15

    Recently the use of brown sugar has increased due to its nutritional characteristics, thus requiring a more rigid quality control. The development of a method for water content analysis in soft brown sugar is carried out for the first time by TG/DTA with application of different statistical tests. The results of the optimization study suggest that heating rates of 5°C min(-1) and an alumina sample holder improve the efficiency of the drying process. The validation study showed that thermo gravimetry presents good accuracy and precision for water content analysis in soft brown sugar samples. This technique offers advantages over other analytical methods as it does not use toxic and costly reagents or solvents, it does not need any sample preparation, and it allows the identification of the temperature at which water is completely eliminated in relation to other volatile degradation products. This is an important advantage over the official method (loss on drying). Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Preprocessing and Content/Navigational Pages Identification as Premises for an Extended Web Usage Mining Model Development

    Directory of Open Access Journals (Sweden)

    Daniel MICAN

    2009-01-01

    Full Text Available From its appearance until nowadays, the internet saw a spectacular growth not only in terms of websites number and information volume, but also in terms of the number of visitors. Therefore, the need of an overall analysis regarding both the web sites and the content provided by them was required. Thus, a new branch of research was developed, namely web mining, that aims to discover useful information and knowledge, based not only on the analysis of websites and content, but also on the way in which the users interact with them. The aim of the present paper is to design a database that captures only the relevant data from logs in a way that will allow to store and manage large sets of temporal data with common tools in real time. In our work, we rely on different web sites or website sections with known architecture and we test several hypotheses from the literature in order to extend the framework to sites with unknown or chaotic structure, which are non-transparent in determining the type of visited pages. In doing this, we will start from non-proprietary, preexisting raw server logs.

  8. Development of low radio-activated cement. Characteristics of cement and clinker that decreased liquid phase content

    International Nuclear Information System (INIS)

    Ichitsubo, Koki

    2008-01-01

    Low radio-activated cement was developed by decreasing the parent elements of radionuclides in the materials. The characteristics of products, decreasing method of Na, Eu and Co in cement, design, tests, evaluation, and analysis of low radio-activated cement clinker are reported. In order to decrease the content of Na, Eu and Co, the raw materials have to include natural materials such as limestone and silica stone. The production method is the same as white cement. The low radio-activated cement produced by rotary kiln showed 4.9% C 3 A, 1.1% C 4 AF, 26.9% C 3 S and 61.0% C 2 S, which values were standardized by the Japanese Industrial Standards (JIS) of low temperature Portland cement. Another product that decreased a little more liquid phase content showed 4.0% C 3 A, 1.0% C 4 AF, 32.3% C 3 S and 56.5% C 2 S, which was standardized by JIS of sulfate resisting Portland cement. In the case of decommissioning reactor constructed by the low radio-activated cement, the whole amount of waste cement will be no more than the clearance level. (S.Y.)

  9. Making Learning Visible: Developing Preservice Teachers' Pedagogical Content Knowledge and Teaching Efficacy Beliefs in Environmental Education

    Science.gov (United States)

    Richardson, Greer M.; Byrne, Laurel L.; Liang, Ling L.

    2018-01-01

    Recognizing that teaching efficacy beliefs influence pedagogical content knowledge, this study assesses the impact of a general methods course on preservice teachers' efficacy beliefs and instructional planning of environmental education content. The course used explicit and visible strategies to support pedagogical and content knowledge…

  10. Investigating the effect of question-driven pedagogy on the development of physics teacher candidates' pedagogical content knowledge

    Science.gov (United States)

    Milner-Bolotin, Marina; Egersdorfer, Davor; Vinayagam, Murugan

    2016-12-01

    This paper describes the second year of a multi-year study on the implementation of Peer Instruction and PeerWise-inspired pedagogies in a physics methods course in a teacher education program at a large research university in Western Canada. In the first year of this study, Peer Instruction was implemented consistently in the physics methods course and teacher candidates were asked to submit five conceptual multiple-choice questions as a final assignment. In the second year of the study we incorporated PeerWise online tool to facilitate teacher candidates' design of conceptual questions by allowing them to provide and receive feedback from their peers, and consequently improve their questions. We have found that as a result of this collaboration teacher candidates improved their pedagogical content knowledge as measured by the rubric developed for the study.

  11. Investigating the effect of question-driven pedagogy on the development of physics teacher candidates’ pedagogical content knowledge

    Directory of Open Access Journals (Sweden)

    Marina Milner-Bolotin

    2016-09-01

    Full Text Available This paper describes the second year of a multi-year study on the implementation of Peer Instruction and PeerWise-inspired pedagogies in a physics methods course in a teacher education program at a large research university in Western Canada. In the first year of this study, Peer Instruction was implemented consistently in the physics methods course and teacher candidates were asked to submit five conceptual multiple-choice questions as a final assignment. In the second year of the study we incorporated PeerWise online tool to facilitate teacher candidates’ design of conceptual questions by allowing them to provide and receive feedback from their peers, and consequently improve their questions. We have found that as a result of this collaboration teacher candidates improved their pedagogical content knowledge as measured by the rubric developed for the study.

  12. Multivariate calibration on NIR data: development of a model for the rapid evaluation of ethanol content in bakery products.

    Science.gov (United States)

    Bello, Alessandra; Bianchi, Federica; Careri, Maria; Giannetto, Marco; Mori, Giovanni; Musci, Marilena

    2007-11-05

    A new NIR method based on multivariate calibration for determination of ethanol in industrially packed wholemeal bread was developed and validated. GC-FID was used as reference method for the determination of actual ethanol concentration of different samples of wholemeal bread with proper content of added ethanol, ranging from 0 to 3.5% (w/w). Stepwise discriminant analysis was carried out on the NIR dataset, in order to reduce the number of original variables by selecting those that were able to discriminate between the samples of different ethanol concentrations. With the so selected variables a multivariate calibration model was then obtained by multiple linear regression. The prediction power of the linear model was optimized by a new "leave one out" method, so that the number of original variables resulted further reduced.

  13. Development of a spectrofluorimetry-based device for determining the acetylene content in the oils of power transformers.

    Science.gov (United States)

    Quintella, Cristina M; Meira, Marilena; Silva, Weidson Leal; Filho, Rogério G D; Araújo, André L C; Júnior, Elias T S; Sales, Lindolfo J O

    2013-12-15

    Power transformers are essential for a functioning electrical system and therefore require special attention by maintenance programs because a fault can harm both the company and society. The temperature inside a power transformer and the dissolved gases, which are primarily composed of acetylene, are the two main parameters monitored when detecting faults. This paper describes the development of a device for analyzing the acetylene content in insulating oil using spectrofluorimetry. Using this device introduces a new methodology for the maintaining and operating power transformers. The prototype is currently operating in a substation. The results presented by this system were satisfactory; when compared to chromatographic data, the errors did not exceed 15%. This prototype may be used to confirm the quality of an insulating oil sample to detect faults in power transformers. © 2013 Elsevier B.V. All rights reserved.

  14. Glass composition development for plasma processing of Hanford high sodium content low-level radioactive liquid waste

    International Nuclear Information System (INIS)

    Marra, J.C.

    1995-02-01

    To assess the acceptability of prospective compositions, response criteria based on durability, homogeneity, viscosity and volatility were defined. Response variables were weighted: durability 35%, homogeneity 25%, viscosity 25%, volatility 15%. A Plackett-Burman experimental design was used to define the first twelve glass formulations. Glass former additives included Al2O3, B2O3, CaO, Li2O, ZrO2 and SiO2. Lithia was added to facilitate fritting of the additives. The additives were normalized to silica content to ease experimental matrix definition and glass formulation. Preset high and low values of these ratios were determined for the initial twelve melts. Based on rankings of initial compositions, new formulations for testing were developed based on a simplex algorithm. Rating and ranking of subsequent compositions continued until no apparent improvement in glass quality was achieved in newly developed formulations. An optimized composition was determined by averaging the additive component values of the final best performing compositions. The glass former contents to form the optimized glass were: 16.1 wt % Al2O3, 12.3 wt % B2O3, 5.5 wt % CaO, 1.7 wt % Li2O, 3.3 wt % ZrO2, 61.1 wt % SiO2. An optimized composition resulted after only 25 trials despite studying six glass additives. A vitrification campaign was completed using a small-scale Joule heated melter. 80 lbs of glass was produced over 96 hours of continuous operation. Several salt compounds formed and deposited on melter components during the run and likely caused the failure of several pour chamber heaters. In an attempt to minimize sodium volatility, several low or no boron glasses were formulated. One composition containing no boron produced a homogeneous glass worthy of additional testing

  15. Gut microbiota and lipopolysaccharide content of the diet influence development of regulatory T cells: studies in germ-free mice.

    Science.gov (United States)

    Hrncir, Tomas; Stepankova, Renata; Kozakova, Hana; Hudcovic, Tomas; Tlaskalova-Hogenova, Helena

    2008-11-06

    Mammals are essentially born germ-free but the epithelial surfaces are promptly colonized by astounding numbers of bacteria soon after birth. The most extensive microbial community is harbored by the distal intestine. The gut microbiota outnumber ~10 times the total number of our somatic and germ cells. The host-microbiota relationship has evolved to become mutually beneficial. Studies in germ-free mice have shown that gut microbiota play a crucial role in the development of the immune system. The principal aim of the present study was to elucidate whether the presence of gut microbiota and the quality of a sterile diet containing various amounts of bacterial contaminants, measured by lipopolysaccharide (LPS) content, can influence maturation of the immune system in gnotobiotic mice. We have found that the presence of gut microbiota and to a lesser extent also the LPS-rich sterile diet drive the expansion of B and T cells in Peyer's patches and mesenteric lymph nodes. The most prominent was the expansion of CD4+ T cells including Foxp3-expressing T cells in mesenteric lymph nodes. Further, we have observed that both the presence of gut microbiota and the LPS-rich sterile diet influence in vitro cytokine profile of spleen cells. Both gut microbiota and LPS-rich diet increase the production of interleukin-12 and decrease the production of interleukin-4. In addition, the presence of gut microbiota increases the production of interleukin-10 and interferon-gamma. Our data clearly show that not only live gut microbiota but also microbial components (LPS) contained in sterile diet stimulate the development, expansion and function of the immune system. Finally, we would like to emphasize that the composition of diet should be regularly tested especially in all gnotobiotic models as the LPS content and other microbial components present in the diet may significantly alter the outcome of experiments.

  16. Development, content validity, and piloting of an instrument designed to measure managers' attitude toward workplace breastfeeding support.

    Science.gov (United States)

    Chow, Tan; Wolfe, Edward W; Olson, Beth H

    2012-07-01

    Manager attitude is influential in female employees' perceptions of workplace breastfeeding support. Currently, no instrument is available to assess manager attitude toward supporting women who wish to combine breastfeeding with work. We developed and piloted an instrument to measure manager attitudes toward workplace breastfeeding support entitled the "Managers' Attitude Toward Breastfeeding Support Questionnaire," an instrument that measures four constructs using 60 items that are rated agree/disagree on a 4-point Likert rating scale. We established the content validity of the Managers' Attitude Toward Breastfeeding Support Questionnaire measures through expert content review (n=22), expert assessment of item fit (n=11), and cognitive interviews (n=8). Data were collected from a purposive sample of 185 front-line managers who had experience supervising female employees, and responses were scaled using the Multidimensional Random Coefficients Multinomial Logit Model. Dimensionality analyses supported the proposed four-construct model. Reliability ranged from 0.75 to 0.86, and correlations between the constructs were moderately strong (0.47 to 0.71). Four items in two constructs exhibited model-to-data misfit and/or a low score-measure correlation. One item was revised and the other three items were retained in the Managers' Attitude Toward Breastfeeding Support Questionnaire. Findings of this study suggest that the Managers' Attitude Toward Breastfeeding Support Questionnaire measures are reliable and valid indicators of manager attitude toward workplace breastfeeding support, and future research should be conducted to establish external validity. The Managers' Attitude Toward Breastfeeding Support Questionnaire could be used to collect data in a standardized manner within and across companies to measure and compare manager attitudes toward supporting breastfeeding. Organizations can subsequently develop targeted strategies to improve support for breastfeeding

  17. Developing a patient-centered outcome measure for complementary and alternative medicine therapies I: defining content and format

    Directory of Open Access Journals (Sweden)

    Ritenbaugh Cheryl

    2011-12-01

    Full Text Available Abstract Background Patients receiving complementary and alternative medicine (CAM therapies often report shifts in well-being that go beyond resolution of the original presenting symptoms. We undertook a research program to develop and evaluate a patient-centered outcome measure to assess the multidimensional impacts of CAM therapies, utilizing a novel mixed methods approach that relied upon techniques from the fields of anthropology and psychometrics. This tool would have broad applicability, both for CAM practitioners to measure shifts in patients' states following treatments, and conventional clinical trial researchers needing validated outcome measures. The US Food and Drug Administration has highlighted the importance of valid and reliable measurement of patient-reported outcomes in the evaluation of conventional medical products. Here we describe Phase I of our research program, the iterative process of content identification, item development and refinement, and response format selection. Cognitive interviews and psychometric evaluation are reported separately. Methods From a database of patient interviews (n = 177 from six diverse CAM studies, 150 interviews were identified for secondary analysis in which individuals spontaneously discussed unexpected changes associated with CAM. Using ATLAS.ti, we identified common themes and language to inform questionnaire item content and wording. Respondents' language was often richly textured, but item development required a stripping down of language to extract essential meaning and minimize potential comprehension barriers across populations. Through an evocative card sort interview process, we identified those items most widely applicable and covering standard psychometric domains. We developed, pilot-tested, and refined the format, yielding a questionnaire for cognitive interviews and psychometric evaluation. Results The resulting questionnaire contained 18 items, in visual analog scale format

  18. PNW cetacean muscle biochemistry - Muscle Myoglobin Content and Acid Buffering Capacity of Cetaceans from the Pacific Northwest to Assess Dive Capacity and the Development of Diving Capabilities

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project assesses the development of two important skeletal muscle adaptations for diving (enhanced myoglobin content and acid buffering capacities) in a range...

  19. The importance of content and face validity in instrument development: lessons learnt from service users when developing the Recovering Quality of Life measure (ReQoL).

    Science.gov (United States)

    Connell, Janice; Carlton, Jill; Grundy, Andrew; Taylor Buck, Elizabeth; Keetharuth, Anju Devianee; Ricketts, Thomas; Barkham, Michael; Robotham, Dan; Rose, Diana; Brazier, John

    2018-07-01

    Service user involvement in instrument development is increasingly recognised as important, but is often not done and seldom reported. This has adverse implications for the content validity of a measure. The aim of this paper is to identify the types of items that service users felt were important to be included or excluded from a new Recovering Quality of Life measure for people with mental health difficulties. Potential items were presented to service users in face-to-face structured individual interviews and focus groups. The items were primarily taken or adapted from current measures and covered themes identified from earlier qualitative work as being important to quality of life. Content and thematic analysis was undertaken to identify the types of items which were either important or unacceptable to service users. We identified five key themes of the types of items that service users found acceptable or unacceptable; the items should be relevant and meaningful, unambiguous, easy to answer particularly when distressed, do not cause further upset, and be non-judgemental. Importantly, this was from the perspective of the service user. This research has underlined the importance of service users' views on the acceptability and validity of items for use in developing a new measure. Whether or not service users favoured an item was associated with their ability or intention to respond accurately and honestly to the item which will impact on the validity and sensitivity of the measure.

  20. Effects of UV-B Radiation on the Content of Bioactive Components and the Antioxidant Activity of Prunella vulgaris L. Spica during Development

    Directory of Open Access Journals (Sweden)

    Yuhang Chen

    2018-04-01

    Full Text Available The effects of UV-B radiation on the content of bioactive components and the antioxidant activity of Prunella vulgaris L. spica during development were studied. The experimental design involved two levels of UV-B radiation intensity (0 and 120 μW cm−2 nm−1. The results showed that the contents of total flavonoids, rosmarinic acid, caffeic acid and hyperoside, as well as the antioxidant capacities (DPPH● and ABTS•+ scavenging activities, in the spicas significantly decreased during spica development. The content of salviaflaside in the spicas significantly increased during development. The highest contents of total flavonoids, rosmarinic acid, and caffeic acid and the highest antioxidant activities were found in spicas in the full-flowering stage, while the highest content of hyperoside was found in spicas in the bud stage. In addition, the highest content of salviaflaside was found in spicas in the mature-fruiting stage. UV-B radiation significantly promoted the synthesis of secondary metabolites, increased the contents of the main bioactive components in the three developmental stages of isolated dried spicas, and significantly increased the DPPH● and ABTS•+ scavenging activities of P. vulgaris spicas in the mature-fruiting stage. Moreover, the total flavonoids content was positively correlated with the DPPH● and ABTS•+ scavenging activities, and the correlation with the DPPH● scavenging activity was very strong. This result shows that the highest contents of the main bioactive components in the spicas were not all found in the same developmental stages of P. vulgaris. Our research revealed that the best stage for harvesting P. vulgaris spica was between the bud stage and the full-flowering stage since harvesting at this point provides a higher content of bioactive components and a higher antioxidant capacity, which is relevant for medicinal applications.

  1. DEPENDENCE OF VITAMIN CONTENT IN THE GEUM URBANUM AND GEUM RIVALE (GEUM, ROSACEAE ORGANS ON THE RHYTHM OF SEASONAL DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    T. V. Burchenko

    2017-01-01

    Full Text Available The aim of the research is to determine the optimal terms of the accumulation of vitamins by the organs of Geum depending on the rhythms of their seasonal development.Methods. The method for determining the vitamin C is based on the ability of ascorbic acid to change the color to blue in the acidic medium - 2,6 - dichlorophenolindophenol - to the leucoform, while ascorbic acid is oxidized to dehydroascorbic acid. Determination of vitamins A and E was carried out by reversed-phase high-performance liquid chromatography.Results. It was found that the highest indices of vitamin A and E in the leaves of G. urbanum and G. rivale are observed in July. In the rhizomes of avens, the maximum concentration of vitamins A and E is observed in March during their intensive growth, vitamin C in January. Decrease in the supply of rhizomes of plants with vitamins A and E continues in the autumn period, while for the vitamin C it is observed in the early spring. In the inflorescences, at the beginning of flowering, G. rivale L. and G. urbanum L. are characterized by the greatest content of vitamin A; by the end of flowering, vitamins E and C are accumulated more intensively.Conclusion. The leaves of wintering plants of G. urbanum L. and G. rivale L. continue to contain vitamins A, E, C despite low temperatures under snow cover and are not subject to significant destruction. During the winter rest period, the content of vitamin C in the roots reaches a maximum. 

  2. Psychologist in a Pocket: Lexicon Development and Content Validation of a Mobile-Based App for Depression Screening.

    Science.gov (United States)

    Cheng, Paula Glenda Ferrer; Ramos, Roann Munoz; Bitsch, Jó Ágila; Jonas, Stephan Michael; Ix, Tim; See, Portia Lynn Quetulio; Wehrle, Klaus

    2016-07-20

    Language reflects the state of one's mental health and personal characteristics. It also reveals preoccupations with a particular schema, thus possibly providing insights into psychological conditions. Using text or lexical analysis in exploring depression, negative schemas and self-focusing tendencies may be depicted. As mobile technology has become highly integrated in daily routine, mobile devices have the capacity for ecological momentary assessment (EMA), specifically the experience sampling method (ESM), where behavior is captured in real-time or closer in time to experience in one's natural environment. Extending mobile technology to psychological health could augment initial clinical assessment, particularly of mood disturbances, such as depression and analyze daily activities, such as language use in communication. Here, we present the process of lexicon generation and development and the initial validation of Psychologist in a Pocket (PiaP), a mobile app designed to screen signs of depression through text analysis. The main objectives of the study are (1) to generate and develop a depressive lexicon that can be used for screening text-input in mobile apps to be used in the PiaP; and (2) to conduct content validation as initial validation. The first phase of our research focused on lexicon development. Words related to depression and its symptoms based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and in the ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines classification systems were gathered from focus group discussions with Filipino college students, interviews with mental health professionals, and the review of established scales for depression and other related constructs. The lexicon development phase yielded a database consisting of 13 categories based on the criteria depressive symptoms in the DSM-5 and ICD-10. For the draft of the depression lexicon for

  3. Accessing primary care Big Data: the development of a software algorithm to explore the rich content of consultation records.

    Science.gov (United States)

    MacRae, J; Darlow, B; McBain, L; Jones, O; Stubbe, M; Turner, N; Dowell, A

    2015-08-21

    To develop a natural language processing software inference algorithm to classify the content of primary care consultations using electronic health record Big Data and subsequently test the algorithm's ability to estimate the prevalence and burden of childhood respiratory illness in primary care. Algorithm development and validation study. To classify consultations, the algorithm is designed to interrogate clinical narrative entered as free text, diagnostic (Read) codes created and medications prescribed on the day of the consultation. Thirty-six consenting primary care practices from a mixed urban and semirural region of New Zealand. Three independent sets of 1200 child consultation records were randomly extracted from a data set of all general practitioner consultations in participating practices between 1 January 2008-31 December 2013 for children under 18 years of age (n=754,242). Each consultation record within these sets was independently classified by two expert clinicians as respiratory or non-respiratory, and subclassified according to respiratory diagnostic categories to create three 'gold standard' sets of classified records. These three gold standard record sets were used to train, test and validate the algorithm. Sensitivity, specificity, positive predictive value and F-measure were calculated to illustrate the algorithm's ability to replicate judgements of expert clinicians within the 1200 record gold standard validation set. The algorithm was able to identify respiratory consultations in the 1200 record validation set with a sensitivity of 0.72 (95% CI 0.67 to 0.78) and a specificity of 0.95 (95% CI 0.93 to 0.98). The positive predictive value of algorithm respiratory classification was 0.93 (95% CI 0.89 to 0.97). The positive predictive value of the algorithm classifying consultations as being related to specific respiratory diagnostic categories ranged from 0.68 (95% CI 0.40 to 1.00; other respiratory conditions) to 0.91 (95% CI 0.79 to 1

  4. Development of Criteria for Flashback Propensity in Jet Flames for High Hydrogen Content and Natural Gas Type Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Kalantari, Alireza [Univ. of California, Irvine, CA (United States); Sullivan-Lewis, Elliot [Univ. of California, Irvine, CA (United States); McDonell, Vincent [Univ. of California, Irvine, CA (United States)

    2016-10-17

    Due to increasingly stringent air quality requirements stationary power gas turbines have moved to lean-premixed operation, which reduces pollutant emissions but can result in flashback. Curtailing flashback can be difficult with hydrocarbon fuels and becomes even more challenging when hydrogen is used as the fuel. In fact, flashback is a key operability issue associated with low emission combustion of high hydrogen content fuels. Flashback can cause serious damage to the premixer hardware. Hence, design tools to predict flashback propensity are of interest. Such a design tool has been developed based on the data gathered by experimental study to predict boundary layer flashback using non-dimensional parameters. The flashback propensity of a premixed jet flame has been studied experimentally. Boundary layer flashback has been investigated under turbulent flow conditions at elevated pressures and temperatures (i.e. 3 atm to 8 atm and 300 K to 500 K). The data presented in this study are for hydrogen fuel at various Reynolds numbers, which are representative of practical gas turbine premixer conditions and are significantly higher than results currently available in the literature. Three burner heads constructed of different materials (stainless steel, copper, and zirconia ceramic) were used to evaluate the effect of tip temperature, a parameter found previously to be an important factor in triggering flashback. This study characterizes flashback systematically by developing a comprehensive non-dimensional model which takes into account all effective parameters in boundary layer flashback propensity. The model was optimized for new data and captures the behavior of the new results well. Further, comparison of the model with the single existing study of high pressure jet flame flashback also indicates good agreement. The model developed using the high pressure test rig is able to predict flashback tendencies for a commercial gas turbine engine and can thus serve as a

  5. Analysis of human serum and whole blood for mineral content by ICP-MS and ICP-OES: development of a mineralomics method.

    Science.gov (United States)

    Harrington, James M; Young, Daniel J; Essader, Amal S; Sumner, Susan J; Levine, Keith E

    2014-07-01

    Minerals are inorganic compounds that are essential to the support of a variety of biological functions. Understanding the range and variability of the content of these minerals in biological samples can provide insight into the relationships between mineral content and the health of individuals. In particular, abnormal mineral content may serve as an indicator of illness. The development of robust, reliable analytical methods for the determination of the mineral content of biological samples is essential to developing biological models for understanding the relationship between minerals and illnesses. This paper describes a method for the analysis of the mineral content of small volumes of serum and whole blood samples from healthy individuals. Interday and intraday precision for the mineral content of the blood (250 μL) and serum (250 μL) samples was measured for eight essential minerals--sodium (Na), calcium (Ca), magnesium (Mg), potassium (K), iron (Fe), zinc (Zn), copper (Cu), and selenium (Se)--by plasma spectrometric methods and ranged from 0.635 to 10.1% relative standard deviation (RSD) for serum and 0.348-5.98% for whole blood. A comparison of the determined ranges for ten serum samples and six whole blood samples provided good agreement with literature reference ranges. The results demonstrate that the digestion and analysis methods can be used to reliably measure the content of these minerals and potentially of other minerals.

  6. Development of methods for determination of PAH based on measured CO-content; Metodutveckling foer indirekt bestaemning av PAH-halt utgaaende fraan maett momentan CO-halt

    Energy Technology Data Exchange (ETDEWEB)

    Ingman, Rolf; Schuster, Robert [AaF Energikonsult Stockholm AB, Stockholm (Sweden)

    2001-02-01

    The aim of the project 'Development of methods for determination of PAH based on measured CO-content' is to investigate the possibility to develop a method for continuous optimisation of NO{sub x}-emissions by decreased air ratio, without significant increase of polyaromatic hydrocarbons such as PAH. The general idea has been to find a indirect online method to predict the emissions of heavier hydrocarbons by: - creating a correlation between the content of CO and PAH, - controlling the air ratio by the CO-content, and - integrating the calculated PAH-content from CO-content. Today many boilers are operated with a low air ratio to minimise the NO{sub x} content and the NO{sub x}-fee. A low ratio increases the risk of high CO contents in the flue gas as well as increased contents of VOC and PAH. Other boilers are operated with high air ratios in order to minimise the CO content, which in some cases will result in unnecessary high NO{sub x} emissions. One of the main difficulties in optimising the air ratio to the most environmental friendly level is the lack of a suitable and well proven PAH instrument. There are today no available instruments for instantaneous and continuous measurement of PAH. PAH is normally measured as an average value during a period of at least one hour. It is not possible to detect short peaks. The development of the CO-method has been based on data from a CFB-boiler in Korsta in Sundsvall (Vaermeforskrapport 541). The data shows a clear correlation between THC and CO. The correlation seems to be mostly dependent of moisture content and load. The development presented in the report shows that it is possible to find a method to predict the PAH content from the CO-content in the flue gas. The next phase aims to improve and implement the method, by measurements and adaptation in a plant. The practical use of the method is as a tool to optimise the emission of CO, NO{sub x}, THC and PAH and/or to predict the PAH-emission during

  7. Exploring Content Validity of Shore Handwriting Screening and Newly Developed Score Sheet With Pre-Kindergarten Students

    Directory of Open Access Journals (Sweden)

    Denise K. Donica

    2015-07-01

    Full Text Available Background: Limited tools exist to measure handwriting readiness skills of pre-kindergarten students. This study was a preliminary exploration of content validity of the Shore Handwriting Screening (SHS and the newly developed Score Sheet with the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2 in 4- and 5-year-old pre-kindergarten students. Because socioeconomic status (SES is known to impact handwriting skills, data from two different socioeconomic groups were collected. Method: Students from a Lower SES group (n = 36 and a Higher SES group (n = 14 completed the SHS and fine motor composite of the BOT-2. Pearson’s correlation was used to compare scores on the two assessments within the two groups. Results: SHS overall percentage scores were compared to standard scores and composite scores of the BOT-2. SHS scores displayed moderate to high correlation with fine manual control portions of the BOT-2 for the Lower SES group and low to moderate correlation for the same portion in the Higher SES group. Conclusion: SHS and the Score Sheet correlate to fine and visual-motor skill subtests on the fine manual control portions of the BOT-2, which supports the need for further research on the reliability and validity of the Score Sheet for use in practice.

  8. Content Development, Presentation and Delivery for eLearning in Nuclear Science and Engineering: Experiences with Emerging Authoring Tools

    International Nuclear Information System (INIS)

    Bamford, S.; Afriyie, P.; Comlan, E.

    2016-01-01

    Full text: Transference of explicit knowledge starts from content development, and proceeds with packaging and delivery. A comparative study of some selected authoring tools for knowledge creation in Nuclear Sciences and Engineering education is being carried out at the School of Nuclear and Allied Sciences in Accra, Ghana. These authoring tools include commercial software (Macromedia Suite CS6, Learning 6.0) as well as freeware software (Xerte, eXe). A course, X-ray Fluorescence Spectrometry (NSAP 603), at the postgraduate School of Nuclear and Allied Sciences (SNAS), has been selected for migration onto an eLearning platform. Different authoring tools have been employed to create some ICT-based modules for teaching and learning. This paper therefore shares the experiences realized in moving from course syllabus to digitized modules, integrating pedagogical considerations, the strengths and weakness of the selected authoring tools, user-interactivity and usability of the modules produced. The need and the basis for the adoption of an appropriate authoring tool for creation of scientific, mathematical, and engineering documents and learning materials has also been discussed. Leveraging on ICT to produce pedagogically sound learning materials for eLearning platforms promotes interests of students in nuclear sciences, and ensures continuity in producing qualified professionals. (author

  9. Holistic Approach to Secondary Earth Science Teacher Professional Development: the Triad of Project-based Instruction, Earth Science Content, and GIS Technology

    Science.gov (United States)

    Rubino-Hare, L.; Sample, J. C.; Fredrickson, K.; Claesgens, J.; Bloom, N.; Henderson-Dahms, C.; Manone, M.

    2011-12-01

    We have provided two years of professional development for secondary and middle school teachers with a focus on project-based instruction (PBI) using GIS. The EYE-POD project (funded by NSF-ITEST) involved pairs of teachers from Arizona and the surrounding region in two-week institutes during Summer, 2010, and an advanced institute in Summer, 2011. The NAz-POD project (funded by Arizona Department of Education and administered by Science Foundation Arizona) provided similar PD experiences, but the institutes occurred during weekends in the academic year. The institutes were led by a team with expertise in Earth science content, professional development and pedagogy, and GIS. The teachers developed learning modules using the project based learning instructional model. Pedagogy, content, and GIS skills were combined throughout the professional development activities. Academic year follow up by NAU personnel included classroom observations and technical support. For assessing student work we provided a rubric, but learned that teachers were not prepared to assess GIS products in order to determine the level of student understanding. In year two of the project we incorporated strategies for assessment of student products into the professional development. Teacher-participants and their students completed several pre- and post- assessments. Teacher assessments included a geospatial performance assessment, classroom observations, and content tests. Student data collection included attitude and efficacy questionnaires, content tests, and authentic assessments including products using GIS. Content tests were the same for teachers and students and included spatial reasoning, data analysis, and Earth science content. Data was also collected on teacher perception of professional development delivery and self-reported confidence in teaching with PBI and geospatial technology. Student assessments show that improvement occurred in all areas on the content test. Possible factors

  10. Remotely Delivered Exercise-Based Cardiac Rehabilitation: Design and Content Development of a Novel mHealth Platform.

    Science.gov (United States)

    Rawstorn, Jonathan C; Gant, Nicholas; Meads, Andrew; Warren, Ian; Maddison, Ralph

    2016-06-24

    Participation in traditional center-based cardiac rehabilitation exercise programs (exCR) is limited by accessibility barriers. Mobile health (mHealth) technologies can overcome these barriers while preserving critical attributes of center-based exCR monitoring and coaching, but these opportunities have not yet been capitalized on. We aimed to design and develop an evidence- and theory-based mHealth platform for remote delivery of exCR to any geographical location. An iterative process was used to design and develop an evidence- and theory-based mHealth platform (REMOTE-CR) that provides real-time remote exercise monitoring and coaching, behavior change education, and social support. The REMOTE-CR platform comprises a commercially available smartphone and wearable sensor, custom smartphone and Web-based applications (apps), and a custom middleware. The platform allows exCR specialists to monitor patients' exercise and provide individualized coaching in real-time, from almost any location, and provide behavior change education and social support. Intervention content incorporates Social Cognitive Theory, Self-determination Theory, and a taxonomy of behavior change techniques. Exercise components are based on guidelines for clinical exercise prescription. The REMOTE-CR platform extends the capabilities of previous telehealth exCR platforms and narrows the gap between existing center- and home-based exCR services. REMOTE-CR can complement center-based exCR by providing an alternative option for patients whose needs are not being met. Remotely monitored exCR may be more cost-effective than establishing additional center-based programs. The effectiveness and acceptability of REMOTE-CR are now being evaluated in a noninferiority randomized controlled trial.

  11. The time-course of broiler intestinal microbiota development after administration of cecal contents to incubating eggs

    Directory of Open Access Journals (Sweden)

    Erin E. Donaldson

    2017-07-01

    Full Text Available Background The microbial populations that inhabit the gastrointestinal tract (GIT are known to influence the health and growth performance of the host. Clean hatcheries and machine-based incubation practices in the commercial poultry industry can lead to the acquisition of aberrant microbiota in the GIT of chickens and a very high level of bird-to-bird variation. The lack of microbial profile flock uniformity presents challenges for harnessing and manipulating intestinal bacteria to better serve the host. Methods Cecal contents from high or low performing chickens were used to inoculate the surface of eggs prior to hatching and then the initial gut colonisation was monitored and subsequent changes in gut microbiota composition were followed over time. Two different cecal treatment groups were compared to an untreated control group (n = 32. Bacterial communities were characterised using high-throughput 16S rRNA gene sequencing techniques. Results Cecal microbiota transfer via egg surface application did not transfer the performance profile of the donors to the recipient birds. One of the cecal inoculations provided a more uniform gut microbiota, but this was not reproduced in the second group with a different inoculum. Development of the intestinal community was reproducible in all three groups with some genera like Lactobacillus showing no change, others like Faecalibacterium increased in abundance slowly and steadily over time and others like Enterobacter were abundant only in the first days of life. Discussion The cecal treatment reduced bird-to-bird variation in microbiota composition. Although the high FCR performance of donor birds was not transferred with the cecal microbiota, all three groups, including the control, performed better than standard for the breed. The pattern of microbiota development was similar in all three flocks, indicating that the normal processes of microbiota acquisition largely swamped any effect of the cecal

  12. Using Multiple Lenses to Examine the Development of Beginning Biology Teachers' Pedagogical Content Knowledge for Teaching Natural Selection Simulations

    Science.gov (United States)

    Sickel, Aaron J.; Friedrichsen, Patricia

    2018-01-01

    Pedagogical content knowledge (PCK) has become a useful construct to examine science teacher learning. Yet, researchers conceptualize PCK development in different ways. The purpose of this longitudinal study was to use three analytic lenses to understand the development of three beginning biology teachers' PCK for teaching natural selection…

  13. Role of the Information Professional in the Development and Promotion of Digital Humanities Content for Research, Teaching, and Learning in the Modern Academic Library: An Irish Case Study

    Science.gov (United States)

    Burns, Jane A.

    2016-01-01

    The Internet has been the catalyst for the convergence of many subject areas and online platforms. Information professionals such as Archivists, IT developers and especially Librarians have been impacted in the development and promotion of digital humanities content for research, teaching, and learning in the modern academic library. In this case…

  14. Development of Prediction Model and Experimental Validation in Predicting the Curcumin Content of Turmeric (Curcuma longa L.)

    OpenAIRE

    Akbar, Abdul; Kuanar, Ananya; Joshi, Raj K.; Sandeep, I. S.; Mohanty, Sujata; Naik, Pradeep K.; Mishra, Antaryami; Nayak, Sanghamitra

    2016-01-01

    The drug yielding potential of turmeric (Curcuma longa L.) is largely due to the presence of phyto-constituent ‘curcumin’. Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influe...

  15. Effect of lead content on phase evolution and microstructural development in Ag-clad Bi-2223 composite conductors

    International Nuclear Information System (INIS)

    Merchant, N.N.; Maroni, V.A.; Fischer, A.K.; Dorris, S.E.; Zhong, W.; Ashcom, N.

    1997-02-01

    A two powder process was used to prepare silver-sheathed monofilamentary Bi 1.8 Pb x Sr 1.98 Ca 1.97 Cu 3.08 O y (Bi-2223) tapes with varying lead contents, x, from 0.2 to 0.5. The resulting tapes were subjected to thermomechanical processing and then characterized by x-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive x-ray analysis (EDX). Layered phase texture was accessed using image analysis software on scanned SEM micrographs. Transport currents were measured at 77 K and zero field by the four-probe method. It was found that tapes with low lead content (X = 0.2 and 0.25) showed incomplete conversion to Bi-2223, had small grain size and poor c-axis texture. Tapes having higher lead content (x = 0.4 and 0.5) also showed incomplete conversion and the presence of lead-rich secondary phases. Tapes with lead content x = 0.3 and 0.35 showed complete conversion to Bi-2223, and had the least amount of secondary phases, the best c-axis texture, and the highest transport current (j c ). The carbon content of the precursor powder also had a strong influence on secondary-phase chemistry

  16. Changes of blood and myocardial tissue contents of IGF-I after development of acute myocardial infarction in rat models

    International Nuclear Information System (INIS)

    Cao Heng; Wei Youquan

    2006-01-01

    Objective: To study the changes of IGF-I contents in blood and myocardium after experimental acute myocardial infarction in rat models. Methods: Rat models of acute myocardial infarction were prepared with intraperitoneal injection of isoproterenol. Eight models were sacrificed 48h later and another 8 models were sacrificed 14 days after preparation. Serum and myocardium homogenate contents of IGF-I were measured with RIA in these models as well as 8 control rats. Results: The serum and myocardial contents of IGF-I increased in the models sacrificed at 48h, but were not significantly higher than those in the controls (P>0.05). At 14 th day, the levels were significantly higher than those in controls and at 48h (both P<0.05). The serum and myocardial contents of IGF-I were mutually correlated in the controls and 14 day models (r=0.9987, r=0.9992; P<0.01). Conclusion After myocardial infarction, the serum and myocardial IGF-I contents increased along with the course of disease in the rat models. (authors)

  17. Qualitative Content Analysis

    OpenAIRE

    Philipp Mayring

    2000-01-01

    The article describes an approach of systematic, rule guided qualitative text analysis, which tries to preserve some methodological strengths of quantitative content analysis and widen them to a concept of qualitative procedure. First the development of content analysis is delineated and the basic principles are explained (units of analysis, step models, working with categories, validity and reliability). Then the central procedures of qualitative content analysis, inductive development of ca...

  18. Development of a new medium frequency EM device: Mapping soil water content variations using electrical conductivity and dielectric permittivity

    Science.gov (United States)

    Kessouri, P.; Buvat, S.; Tabbagh, A.

    2012-12-01

    Both electrical conductivity and dielectric permittivity of soil are influenced by its water content. Dielectric permittivity is usually measured in the high frequency range, using GPR or TDR, where the sensitivity to water content is high. However, its evaluation is limited by a low investigation depth, especially for clay rich soils. Electrical conductivity is closely related not only to soil water content, but also to clay content and soil structure. A simultaneous estimation of these electrical parameters can allow the mapping of soil water content variations for an investigation depth close to 1m. In order to estimate simultaneously both soil electrical conductivity and dielectric permittivity, an electromagnetic device working in the medium frequency range (between 100 kHz and 10 MHz) has been designed. We adopted Slingram geometry for the EM prototype: its PERP configuration (vertical transmission loop Tx and horizontal measuring loop Rx) was defined using 1D ground models. As the required investigation depth is around 1m, the coil spacing was fixed to 1.2m. This prototype works in a frequency range between 1 and 5 MHz. After calibration, we tested the response of prototype to objects with known properties. The first in situ measurements were led on experimental sites with different types of soils and different water content variations (artificially created or natural): sandy alluvium on a plot of INRA (French National Institute for Agricultural Research) in Orléans (Centre, France), a clay-loam soil on an experimental site in Estrée-Mons (Picardie, France) and fractured limestone at the vicinity of Grand (Vosges, France). In the case of the sandy alluvium, the values of dielectric permittivity measured are close to those of HF permittivity and allow the use of existing theoretical models to determine the soil water content. For soils containing higher amount of clay, the coupled information brought by the electrical conductivity and the dielectric

  19. Development of a extensor oil with low content of polycyclic aromatic; Desenvolvimento de oleo extensor com baixo teor de policiclicos aromaticos

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Anie Daniela M.; Fontes, Anita Eleonora F.; Figueiredo, Joao Baptista [PETROBRAS, Rio de Janeiro, RJ (Brazil)] (and others)

    2008-07-01

    This paper presents the development of a substitute product for the aromatic oil used in rubber tires. The new oil must be in according to The European Community Directive 2005/69/EC, which has the start date in January first of 2010. The directive sets limits for specific levels of polyaromatics content in the oils for rubber tires because of the mutagenic and harmful to the reproduction characteristic of some of these substances. The process of aromatics extraction was conducted on several kinds of feedstocks to obtain a product with kinematic viscosity at 100 deg C in the 40-50 cSt range and polycyclics aromatics content until 3% in mass. It is important to know that the current oils have 20% in mass of polyaromatics content. The product developed is in according with the Directive specifications and contributes to the production of tires more suitable to the environment and human health. (author)

  20. On the manganese content of the egg of Oryzias latipes and its change during the early development

    International Nuclear Information System (INIS)

    Hori, R.; Iwasaki, S.I.

    1976-01-01

    The content of manganese of the egg of Oryzias latipes was determined by atomic absorption spectrophotometry and activation analysis. The amount of manganese in the unfertilized egg was 0.51 mμg and increased remarkably in one hour after fertilization. Although the increasing rate became gradually lower in further stages, the content of manganese amounted to 2.61 mμg in the embryo after gastrulation. Tracer-experiments showed that the egg accumulated manganese positively from the surrounding medium during the short time after fertilization. (author)

  1. Effect of Resin Ducts and Sap Content on Infestation and Development of Immature Stages of Anastrepha obliqua and Anastrepha ludens (Diptera: Tephritidae) in Four Mango (Sapindales: Anacardiaceae) Cultivars.

    Science.gov (United States)

    Guillén, Larissa; Adaime, Ricardo; Birke, Andrea; Velázquez, Olinda; Angeles, Guillermo; Ortega, Fernando; Ruíz, Eliel; Aluja, Martín

    2017-04-01

    We determined the influence of resin ducts, sap content, and fruit physicochemical features of four mango cultivars (Criollo, Manila, Ataulfo, and Tommy Atkins) on their susceptibility to the attack of the two most pestiferous fruit fly species infesting mangoes in Mexico: Anastrepha ludens (Loew) and Anastrepha obliqua (Macquart). We performed three studies: 1) analysis of resin ducts in mango fruit exocarp to determine the density and area occupied by resin ducts in each mango cultivar, 2) assessment of mango physicochemical features including fruit sap content, and 3) a forced infestation trial under field conditions using enclosed fruit-bearing branches to expose mangoes to gravid A. ludens or A. obliqua females. Infestation rates, development time from egg to prepupae and pupae, pupal weight, and percent of adult emergence, were assessed. 'Ataulfo' and 'Tommy Atkins' cultivars exhibited the highest resin duct density and sap content, the lowest infestation rate, and had a negative effect on immature development and pupal weight. In sharp contrast, 'Manila' and 'Criollo' cultivars, with the lowest resin duct density and sap content, were highly susceptible to A. ludens and A. obliqua attack. We conclude that sap content and the number, size, and distribution of resin ducts as well as firmness in mango fruit exocarp are all involved in the resistance of mango to A. ludens and A. obliqua attack. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Learning to Critique and Adapt Science Curriculum Materials: Examining the Development of Preservice Elementary Teachers' Pedagogical Content Knowledge

    Science.gov (United States)

    Beyer, Carrie J.; Davis, Elizabeth A.

    2012-01-01

    Teachers often engage in curricular planning by critiquing and adapting existing curriculum materials to contextualize lessons and compensate for their deficiencies. Designing instruction for students is shaped by teachers' ability to apply a variety of personal resources, including their pedagogical content knowledge (PCK). This study…

  3. Application of process analytical technology in tablet process development using NIR spectroscopy : Blend uniformity, content uniformity and coating thickness measurements

    NARCIS (Netherlands)

    Moes, Johannes J; Ruijken, Marco M; Gout, Erik; Frijlink, Henderik W; Ugwoke, Michael I

    2008-01-01

    Near-infrared (NIR)spectroscopy was employed as a process analytical technique in three steps of tabletting process: to monitor the blend homogeneity, evaluate the content uniformity of tablets and determine the tablets coating thickness. A diode-array spectrometer mounted on a lab blender (SP15 NIR

  4. Pre-Service Teachers' Development of Technological Pedagogical Content Knowledge (TPACK) in the Context of a Secondary Science Teacher Education Program

    Science.gov (United States)

    Habowski, Thomas; Mouza, Chrystalla

    2014-01-01

    This study investigates pre-service teachers' TPACK development in a secondary science teacher education program that combined a content-specific technology integration course with extensive field experience. Both quantitative and qualitative data were collected. Quantitative data were collected through a pre-post administration of the…

  5. The Analysis of Content and Operational Components of Public School Teachers' Continuing Professional Development in Great Britain, Canada and the USA

    Science.gov (United States)

    Mukan, Nataliya; Kravets, Svitlana; Khamulyak, Nataliya

    2016-01-01

    In the article the content and operational components of continuing professional development of public school teachers in Great Britain, Canada, the USA have been characterized. The main objectives are defined as the theoretical analysis of scientific-pedagogical literature, which highlights different aspects of the problem under research;…

  6. Development and Preliminary Face and Content Validation of the "Which Health Approaches and Treatments Are You Using?" (WHAT) Questionnaires Assessing Complementary and Alternative Medicine Use in Pediatric Rheumatology.

    Science.gov (United States)

    Toupin April, Karine; Stinson, Jennifer; Boon, Heather; Duffy, Ciarán M; Huber, Adam M; Gibbon, Michele; Descarreaux, Martin; Spiegel, Lynn; Vohra, Sunita; Tugwell, Peter

    2016-01-01

    Complementary and alternative medicine (CAM) is commonly used by children with juvenile idiopathic arthritis (JIA), yet no validated questionnaires assess that use. The objective of this study was to develop child self- and parent proxy-report questionnaires assessing CAM use and to determine the face and content validity of the "Which Health Approaches and Treatments are you using?" (WHAT) questionnaires in pediatric rheumatology. A sequential phased mixed methods approach was used to develop the questionnaires. A Delphi Survey of 126 experts followed by an interdisciplinary consensus conference of 14 stakeholders in CAM, general pediatrics and pediatric rheumatology was held to develop consensus on the content of the questionnaires using a nominal group technique. To determine face and content validity of the questionnaires, two groups, including (a) a purposive sample of 22 children with JIA 8 to 18 years and their parents from the Children's Hospital of Eastern Ontario and the Hospital for Sick Children, and (b) 21 Canadian pediatric rheumatology experts, participated in interviews. Participants were independently asked about the goal, understandability and comprehensiveness of the WHAT questionnaires, as well as the relevance of items. Consensus was reached on 17 items of the WHAT questionnaires. The domains found to be relevant were child's CAM use, factors associated with CAM use, perceived impact of CAM use, and communication about CAM. A total of 15 items in the parent proxy-report questionnaire and 13 items in the child report questionnaire showed adequate content validity. Consensus was reached by experts on the content of a pediatric CAM questionnaire. Face and content validity testing and modifications made to the WHAT questionnaires have helped ensure adequate preliminary validity for use in pediatric rheumatology. This constitutes the basis for further testing of these questionnaires in pediatric rheumatology and for adaptation to other chronic

  7. Development and Preliminary Face and Content Validation of the "Which Health Approaches and Treatments Are You Using?" (WHAT Questionnaires Assessing Complementary and Alternative Medicine Use in Pediatric Rheumatology.

    Directory of Open Access Journals (Sweden)

    Karine Toupin April

    Full Text Available Complementary and alternative medicine (CAM is commonly used by children with juvenile idiopathic arthritis (JIA, yet no validated questionnaires assess that use. The objective of this study was to develop child self- and parent proxy-report questionnaires assessing CAM use and to determine the face and content validity of the "Which Health Approaches and Treatments are you using?" (WHAT questionnaires in pediatric rheumatology.A sequential phased mixed methods approach was used to develop the questionnaires. A Delphi Survey of 126 experts followed by an interdisciplinary consensus conference of 14 stakeholders in CAM, general pediatrics and pediatric rheumatology was held to develop consensus on the content of the questionnaires using a nominal group technique. To determine face and content validity of the questionnaires, two groups, including (a a purposive sample of 22 children with JIA 8 to 18 years and their parents from the Children's Hospital of Eastern Ontario and the Hospital for Sick Children, and (b 21 Canadian pediatric rheumatology experts, participated in interviews. Participants were independently asked about the goal, understandability and comprehensiveness of the WHAT questionnaires, as well as the relevance of items.Consensus was reached on 17 items of the WHAT questionnaires. The domains found to be relevant were child's CAM use, factors associated with CAM use, perceived impact of CAM use, and communication about CAM. A total of 15 items in the parent proxy-report questionnaire and 13 items in the child report questionnaire showed adequate content validity.Consensus was reached by experts on the content of a pediatric CAM questionnaire. Face and content validity testing and modifications made to the WHAT questionnaires have helped ensure adequate preliminary validity for use in pediatric rheumatology. This constitutes the basis for further testing of these questionnaires in pediatric rheumatology and for adaptation to other

  8. Dynamic carbon content as an indicator of desertification processes in soils developed from volcanic parental material in the Region of Murcia

    International Nuclear Information System (INIS)

    Martinez-Martinez, S.; Faz Cano, A.; Acosta Aviles, J. A.

    2009-01-01

    Soil Organic Carbon (SOC is an essential components of the global carbon cycle, especially in soils developed from volcanic rocks, due to these soils does not have inorganic carbon. In arid and semiarid areas mineralization of organic carbon is very intense due to climatic conditions, causing soils depletion and therefore desertification. The objective of this study is to determine the content of OC, as a first step in the assessment of desertification. The objective of this study is to determine the content of OC, as a first step in the assessment of desertification processes affecting this area of the southeast of Spain. (Author) 7 refs.

  9. GAME AS EXPRESSION OF CULTURE BODY MOTION IN PHYSICAL EDUCATION SCHOOL: the three dimensions of content and the development of critical thinking.

    Directory of Open Access Journals (Sweden)

    Daniel Teixeira Maldonado

    2016-09-01

    Full Text Available The physical education (PE contributes, through their content and working techniques, with the integral development of the child. This paper describes an educational experiment carried out with students from the 7th grade of elementary school to a public school of the east side of São Paulo where the games were themed on the three dimensions of content in view of the proposed political pedagogical project of the school. Students were encouraged to reflect, analyze and discuss the games experienced and his lines showed the presence of critical thinking on the subject.

  10. Local Content

    CSIR Research Space (South Africa)

    Gibberd, Jeremy

    2016-10-01

    Full Text Available Local content refers to materials and products made in a country as opposed those that are imported. There is an increasing interest in the concept of local content as a means of supporting local economies and providing jobs (Belderbos & Sleuwaegen...

  11. Determining the Feasibility, Content Validity, and Internal Consistency of a Newly Developed Care Coordination Scale for People with Brain Injury

    Directory of Open Access Journals (Sweden)

    Brian P. Johnson

    2017-07-01

    Full Text Available Background: With the increasing complexity of care, people with disabilities and supportive significant others (SSO must often coordinate key aspects of their own care, but no validated scale currently exists to comprehensively characterize the activities done to manage and coordinate their care. Method: This study aimed to improve the feasibility, acceptability, and content validity of the Care and Service Coordination and Management (CASCAM scale and to test its internal consistency. Questionnaire items were administered to 23 individuals with acquired brain injury and 17 SSO. Results: Respondents confirmed content validity and that the instrument addresses important care coordination and management issues. The internal consistency of care coordination domains for medical/ rehabilitative and independent living needs for people with brain injury and their SSO ranged from α = .774 to .945. Conclusion: Care coordination activities by persons with disabilities, including brain injury, and their SSO are multifaceted but feasibly measurable and should be assessed to improve care.

  12. Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology.

    Science.gov (United States)

    Wang, Lucy L; Grunblatt, Eli; Jung, Hyunggu; Kalet, Ira J; Whipple, Mark E

    2015-01-01

    Constructing a biological model using an established ontology provides a unique opportunity to perform content auditing on the ontology. We built a Markov chain model to study tumor metastasis in the regional lymphatics of patients with head and neck squamous cell carcinoma (HNSCC). The model attempts to determine regions with high likelihood for metastasis, which guides surgeons and radiation oncologists in selecting the boundaries of treatment. To achieve consistent anatomical relationships, the nodes in our model are populated using lymphatic objects extracted from the Foundational Model of Anatomy (FMA) ontology. During this process, we discovered several classes of inconsistencies in the lymphatic representations within the FMA. We were able to use this model building opportunity to audit the entities and connections in this region of interest (ROI). We found five subclasses of errors that are computationally detectable and resolvable, one subclass of errors that is computationally detectable but unresolvable, requiring the assistance of a content expert, and also errors of content, which cannot be detected through computational means. Mathematical descriptions of detectable errors along with expert review were used to discover inconsistencies and suggest concepts for addition and removal. Out of 106 organ and organ parts in the ROI, 8 unique entities were affected, leading to the suggestion of 30 concepts for addition and 4 for removal. Out of 27 lymphatic chain instances, 23 were found to have errors, with a total of 32 concepts suggested for addition and 15 concepts for removal. These content corrections are necessary for the accurate functioning of the FMA and provide benefits for future research and educational uses.

  13. Effect of inflow discharges on the development of matric suction and volumetric water content for dike during overtopping tests

    Science.gov (United States)

    Hassan, Marwan A.; Ismail, Mohd A. M.

    2017-10-01

    The point of this review is to depict the impact of various inflow discharge rate releases on the instruments of matric suction and volumetric water content during an experimental test of spatial overtopping failure at school of civil engineering in universiti Sains of Malaysia. A dry sand dike was conducted inside small flume channel with twelve sensors of tensiometer and Time-Domain Reflectometer (TDR). Instruments are installed in the soil at different locations in downstream and upstream slopes of the dike for measuring the response of matric suction and volumetric water content, respectively. Two values of inflow discharge rates of 30 and 40 L/min are utilized as a part of these experiments to simulate the effectiveness of water reservoirs in erosion mechanism. The outcomes demonstrate that the matric suction and volumetric water content are decreased and increased, respectively for both inflow discharges. The higher inflow discharges accelerate the saturation of dike soil and the erosion process faster than that for the lower inflow discharges.

  14. Program of neuropsychological stimulation of cognition in students: Emphasis on executive functions - development and evidence of content validity

    Directory of Open Access Journals (Sweden)

    Caroline de Oliveira Cardoso

    Full Text Available ABSTRACT Objective: The goal of this study was to describe the construction process and content validity evidence of an early and preventive intervention program for stimulating executive functions (EF in Elementary School children within the school environment. Methods: The process has followed the recommended steps for creating neuropsychological instruments: internal phase of program organization, with literature search and analyses of available materials in the classroom; program construction; analysis by expert judges; data integration and program finalization. To determine the level of agreement among the judges, a Content Validity Index (CVI was calculated. Results: Content validity was evidenced by the agreement among the experts with regards to the program, both in general and for each activity. All steps taken were deemed necessary because they contributed to the identification of positive aspects and possible flaws in the process Conclusion: The steps also helped to adapt stimuli and improve program tasks and activities. Methodological procedures implemented in this study can be adopted by other researchers to create or adapt neuropsychological stimulation and rehabilitation programs. Furthermore, the methodological approach allows the reader to understand, in detail, the technical and scientific rigor adopted in devising this program.

  15. The Development and User Satisfaction Evaluation of Internet-Based N-Screen Healthcare Walking Content to Increase Continuous Usage Motivation.

    Science.gov (United States)

    Youm, Sekyoung

    2015-08-01

    The purpose of the current study is (1) to apply Internet-based N-Screen (this is used like the term "emultiscreen"; as the technology that provides services of shared content or application via N devices, it includes all screens such as personal computers [PCs], TV, and mobile devices) services to healthcare services by developing games for improving one's health and (2) to present ways to activate the use of health promotion contents in the future by investigating user satisfaction and whether there is any intention to accept the contents and/or use the services continuously. In order to evaluate the customized health maintenance content provided by the healthcare walking system developed in the current study, 98 adult men and women residing in Seoul, Korea, were instructed to use 10 minutes' worth of the walking content. Perceived quality, level of trust in the results, effectiveness of the exercise, and overall satisfaction were measured in regard to the N-Screen-based walking content, including those for the cell phone, PC, and Internet protocol TV (IPTV). Walking contents using N-Screen services were perceived with high levels of trust in the results of the exercise, the effectiveness of the exercise, and overall satisfaction. In terms of the usability of N-Screen services, the younger the participants, the more usable they found the mobile or PC programs. The older the participants, the more usable they found the IPTV screens, although they still struggled with using the content given; operating IPTVs proved to be difficult for them. Furthermore, participants who were engaged in exercise on a regular basis were less satisfied with the program, in general. The present study has developed a walking system using N-Screen programs to make the most common and effective forms of exercise-walking and running-accessible indoors. This may increase motivation to exercise by offering services that boost one's interest in exercising, such as personal monitoring and real

  16. A new strategy for umbilical cord blood collection developed at the first Colombian public cord blood bank increases total nucleated cell content.

    Science.gov (United States)

    Vanegas, Diana; Triviño, Lady; Galindo, Cristian; Franco, Leidy; Salguero, Gustavo; Camacho, Bernardo; Perdomo-Arciniegas, Ana-María

    2017-09-01

    The total nucleated cell dosage of umbilical cord blood (UCB) is an important factor in determining successful allogeneic hematopoietic stem cell transplantation after a minimum human leukocyte antigen donor-recipient match. The northern South American population is in need of a new-generation cord blood bank that cryopreserves only units with high total nucleated cell content, thereby increasing the likelihood of use. Colombia set up a public cord blood bank in 2014; and, as a result of its research for improving high total nucleated cell content, a new strategy for UCB collection was developed. Data from 2933 collected and 759 cryopreserved cord blood units between 2014 and 2015 were analyzed. The correlation of donor and collection variables with cellularity was evaluated. Moreover, blood volume, cell content, CD34+ count, clonogenic capacity, and microbial contamination were assessed comparing the new method, which combines in utero and ex utero techniques, with the conventional strategies. Multivariate analysis confirmed a correlation between neonatal birth weight and cell content. The new collection method increased total nucleated cell content in approximately 26% and did not alter pre-cryopreservation and post-thaw cell recovery, viability, or clonogenic ability. Furthermore, it showed a remarkably low microbial contamination rate (1.2%). The strategy for UCB collection developed at the first Colombian public cord blood bank increases total nucleated cell content and does not affect unit quality. The existence of this bank is a remarkable breakthrough for Latin-American patients in need of this kind of transplantation. © 2017 The Authors Transfusion published by Wiley Periodicals, Inc. on behalf of AABB.

  17. Content Maps: A Teaching and Assessment Tool for Content Knowledge

    Science.gov (United States)

    Ward, Phillip; Lehwald, Harry; Lee, Yun Soo

    2015-01-01

    Developing content knowledge in teachers presents a constant challenge for teacher educators. This article introduces a teaching and assessment tool called a "content map," which allows teacher educators, teachers, and coaches to conceptualize the scope, sequence, and relational characteristics of the content being taught. Content maps…

  18. Development of Au-Ge based candidate alloys as an alternative to high-lead content solders

    DEFF Research Database (Denmark)

    Chidambaram, Vivek; Hald, John; Hattel, Jesper Henri

    2010-01-01

    Au-Ge based candidate alloys have been proposed as an alternative to high-lead content solders that are currently being used for high-temperature applications. The changes in microstructure and microhardness associated with the addition of low melting point metals namely In, Sb and Sn to the Au......-Ge-In and Au-Ge-Sn combinations was determined to be the classic solid solution strengthening. The Au-Ge-Sb combination was primarily strengthened by the refined (Ge) dispersed phase. The aging temperature had a significant influence on the microhardness in the case of the Au-Ge-Sn candidate alloy...

  19. Developing and Deploying an XML-based Learning Content Management System at the FernUniversität Hagen

    Directory of Open Access Journals (Sweden)

    Gerd Steinkamp

    2005-02-01

    Full Text Available This paper is a report about the FuXML project carried out at the FernUniversität Hagen. FuXML is a Learning Content Management System (LCMS aimed at providing a practical and efficient solution for the issues attributed to authoring, maintenance, production and distribution of online and offline distance learning material. The paper presents the environment for which the system was conceived and describes the technical realisation. We discuss the reasons for specific implementation decisions and also address the integration of the system within the organisational and technical infrastructure of the university.

  20. Development of glass compositions with 9% waste content for the vitrification of high-level waste from LWR nuclear reactors

    International Nuclear Information System (INIS)

    Lakatos, T.

    1979-10-01

    Reduction of the contents of waste in glass from 20-25% to 9% causes a decrease of the leaching resistance of the glass. The addition of Zn0 reduces the leaching values by a factor of approximately 10. The crystallized glass ceramics have a lower coefficient of thermal expansion than glassy waste bodies. The separation of the phase which contains Mo occurs during heat treatment. The amount of separated Mo is lower for low alkali sac type (Si0 2 - A1 2 0 3 -Ca0 system) of glasses by a factor of approximately 50. All the glasses were prepared with simulated waste composition. (GBn.)

  1. Limited potential of school textbooks to prevent tobacco use among students grade 1-9 across multiple developing countries: a content analysis study.

    Science.gov (United States)

    Saito, Junko; Nonaka, Daisuke; Mizoue, Tetsuya; Kobayashi, Jun; Jayatilleke, Achini C; Shrestha, Sabina; Kikuchi, Kimiyo; Haque, Syed E; Yi, Siyan; Ayi, Irene; Jimba, Masamine

    2013-01-01

    To evaluate the content of school textbooks as a tool to prevent tobacco use in developing countries. Content analysis was used to evaluate if the textbooks incorporated the following five core components recommended by the WHO: (1) consequences of tobacco use; (2) social norms; (3) reasons to use tobacco; (4) social influences and (5) resistance and life skills. Nine developing countries: Bangladesh, Cambodia, Laos, Nepal, Sri Lanka, Benin, Ghana, Niger and Zambia. TEXTBOOKS ANALYSED: Of 474 textbooks for primary and junior secondary schools in nine developing countries, 41 were selected which contained descriptions about tobacco use prevention. Of the 41 textbooks, the consequences of tobacco use component was covered in 30 textbooks (73.2%) and the social norms component was covered in 19 (46.3%). The other three components were described in less than 20% of the textbooks. A rather limited number of school textbooks in developing countries contained descriptions of prevention of tobacco use, but they did not fully cover the core components for tobacco use prevention. The chance of tobacco prevention education should be seized by improving the content of school textbooks.

  2. Low-temperature conditioning of "seed" cloves enhances the expression of phenolic metabolism related genes and anthocyanin content in 'Coreano' garlic (Allium sativum) during plant development.

    Science.gov (United States)

    Dufoo-Hurtado, Miguel D; Zavala-Gutiérrez, Karla G; Cao, Cong-Mei; Cisneros-Zevallos, Luis; Guevara-González, Ramón G; Torres-Pacheco, Irineo; Vázquez-Barrios, M Estela; Rivera-Pastrana, Dulce M; Mercado-Silva, Edmundo M

    2013-11-06

    Low-temperature conditioning of garlic "seed" cloves accelerated the development of the crop cycle, decreased plant growth, and increased the synthesis of phenolic compounds and anthocyanins in the outer scale leaves of the bulbs at harvest time, leading to 3-fold content increase compared with those conditioned at room temperature. Cold conditioning of "seed" cloves also altered the anthocyanin profile during bulb development and at harvest. Two new anthocyanins are reported for the first time in garlic. The high phenolics and anthocyanin contents in bulbs of plants generated from "seed" cloves conditioned at 5 °C for 5 weeks were preceded by overexpression of some putative genes of the phenolic metabolism [6-fold for phenylalanine ammonia lyase (PAL)] and anthocyanin synthesis [1-fold for UDP-sugar:flavonoid 3-O-glycosyltransferase (UFGT)] compared with those conditioned at room temperature.

  3. The Development of a Tool for Measuring Graduate Students' Topic Specific Pedagogical Content Knowledge of Thin Layer Chromatography

    Science.gov (United States)

    Hale, L. V. A.; Lutter, J. C.; Shultz, G. V.

    2016-01-01

    Graduate students play a critical role in undergraduate education at doctorate granting institutions; but generally have minimal opportunity to develop teaching expertise. Furthermore, little is known about how graduate students develop teaching expertise in this context. We investigated the development of topic-specific pedagogical content…

  4. Assessment of leaf carotenoids content with a new carotenoid index: Development and validation on experimental and model data

    Science.gov (United States)

    Zhou, Xianfeng; Huang, Wenjiang; Kong, Weiping; Ye, Huichun; Dong, Yingying; Casa, Raffaele

    2017-05-01

    Leaf carotenoids content (LCar) is an important indicator of plant physiological status. Accurate estimation of LCar provides valuable insight into early detection of stress in vegetation. With spectroscopy techniques, a semi-empirical approach based on spectral indices was extensively used for carotenoids content estimation. However, established spectral indices for carotenoids that generally rely on limited measured data, might lack predictive accuracy for carotenoids estimation in various species and at different growth stages. In this study, we propose a new carotenoid index (CARI) for LCar assessment based on a large synthetic dataset simulated from the leaf radiative transfer model PROSPECT-5, and evaluate its capability with both simulated data from PROSPECT-5 and 4SAIL and extensive experimental datasets: the ANGERS dataset and experimental data acquired in field experiments in China in 2004. Results show that CARI was the index most linearly correlated with carotenoids content at the leaf level using a synthetic dataset (R2 = 0.943, RMSE = 1.196 μg/cm2), compared with published spectral indices. Cross-validation results with CARI using ANGERS data achieved quite an accurate estimation (R2 = 0.545, RMSE = 3.413 μg/cm2), though the RBRI performed as the best index (R2 = 0.727, RMSE = 2.640 μg/cm2). CARI also showed good accuracy (R2 = 0.639, RMSE = 1.520 μg/cm2) for LCar assessment with leaf level field survey data, though PRI performed better (R2 = 0.710, RMSE = 1.369 μg/cm2). Whereas RBRI, PRI and other assessed spectral indices showed a good performance for a given dataset, overall their estimation accuracy was not consistent across all datasets used in this study. Conversely CARI was more robust showing good results in all datasets. Further assessment of LCar with simulated and measured canopy reflectance data indicated that CARI might not be very sensitive to LCar changes at low leaf area index (LAI) value, and in these conditions soil moisture

  5. The ways of improvement of content and pedagogical conditions of preparation of master of preschool education in the context of development of creative potential

    Directory of Open Access Journals (Sweden)

    Oleksandra Iemchyk

    2017-04-01

    Full Text Available The necessity of changes in the process of professional preparation of master of preschool education, which is caused by insufficient preparation of graduates to solve problems in this field, low level of creative potential and, as the consequence, unavailability to realization creative pedagogical activity is outlined in the article. The main ways of improvement of content and pedagogical conditions of development of creative potential of master of preschool education in the process of professional preparation are presented: the improvement of content of scientific theoretical preparation of master, studying of progressive pedagogical experience; learning of professional pedagogical disciplines with the reliance to creative tasks with problem search nature; implementation to the educational process of magistracy of institution of higher education on the specialty “Preschool education” of special course “The foundations of development of creative potential of pedagogue”; attraction of students to the creative pedagogical practice; organization and management of students creative process from the side of teachers. There are also identified the perspectives of solution of the problem of development of creative abilities of personality of pedagogue during the professional preparation in the institution of higher education. The implementation of these ways to the educational process will contribute the increasing the readiness of graduates of institutions of higher education to realize pedagogical activity on the creative level, selfdevelopment and self-improvement of their personality.Key words: creative potential of master of preschool education, the professional preparation, the ways of improvement of content of professional preparation.

  6. Applying Technological Pedagogical and Content Knowledge (TPACK) model to develop an online English writing course for nursing students.

    Science.gov (United States)

    Tai, Hung-Cheng; Pan, Mei-Yu; Lee, Bih-O

    2015-06-01

    Learning English as foreign language and computer technology are two crucial skills for nursing students not only for the use in the medical institutions but also for the communication needs following the trend of globalization. Among language skills, writing has long been ignored in the curriculums although it is a core element of language learning. To apply the TPACK (Technological Pedagogical and Content Knowledge) model to design an online English writing course for nursing students, and to explore the effects of the course to the students' learning progress as well as their satisfactions and perceptions. A single-group experimental study, utilizing the CEEC (College Entrance Examination Center) writing grading criteria and a self-designed course satisfaction questionnaire, is used. Fifty one nursing students who were in their first/four semesters of the two year vocational pre-registration nursing course in a Taiwan university were selected using convenience sampling. Quantitative data were analyzed using descriptive statistics and repeated measure MANOVA. Qualitative data were analyzed by content analysis. Students' writing competence had been improved significantly in every dimension after the instruction. Only half of the learners preferred online writing compared to the traditional way of writing by hand. Additionally, participants reported that they would prefer to receive feedback from the teacher than peers, yet they did not like the indirect feedback. The teacher perceived the course as meaningful but demanding for both learning and teaching sides. To implement the peer review activities and give feedback on time were two major challenges during the cycles. The TPACK model suggests a comprehensive and effective teaching approach that can help enhance nursing students' English writing performance. Teachers are advised to consider its implementation when designing their syllabus. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Development relationship of color with anthocyanins and chlorophyll content in diferent degrees of maturity of mortiño (Vaccinium floribundum

    Directory of Open Access Journals (Sweden)

    Mónica Arteaga Dalgo

    2014-06-01

    Full Text Available The relationship between color development with anthocyanins and chlorophyll content at different stages of maturity of mortiño (Vaccinum floribundum was studied. The fruits were harvested by surface color from 100% green to 100% black. The color scale was measured according to CIE L* a* b* and color difference (∆E was determined. The anthocyanin and chlorophyll content was performed by UV-VIS spectrophotometry. The following scale was used to establish the stage of maturity: (1 green, (2 green/pink, (3 pink, (4 pink/black and (5 black; It was observed that increasing the maturation stage, the brightness and color saturation decrease. Results showed positive values of a* and negative of b* for maturity stages 3, 4 and 5 (red and blue; and negative values ​​of a * and positive of b * for states 1 and 2 (green and yellow. Smallest differences in color (∆E were found between states 4 and 5. Among the states 1 and 5 was evident a decreased of 0,052 mg/g in chlorophyll content and an increase of 13700mg/kg in anthocyanins. The degree of maturity of the fruit has a direct relationship between the color tone and content of components with antioxidant activity constituting a precedent for future researches and its use of this fruit in different stages of maturity.

  8. Development of India-specific RAFM steel through optimization of tungsten and tantalum contents for better combination of impact, tensile, low cycle fatigue and creep properties

    Energy Technology Data Exchange (ETDEWEB)

    Laha, K., E-mail: laha@igcar.gov.in [Metallurgy and Materials Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102, TN (India); Saroja, S.; Moitra, A.; Sandhya, R.; Mathew, M.D.; Jayakumar, T. [Metallurgy and Materials Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102, TN (India); Rajendra Kumar, E. [Institute for Plasma Research, Bhat, Gandhinagar 382 428, Gujarat (India)

    2013-08-15

    Effects of tungsten and tantalum contents on impact, tensile, low cycle fatigue and creep properties of Reduced Activation Ferritic–Martensitic (RAFM) steel were studied to develop India-specific RAFM steel. Four heats of the steel have been melted with tungsten and tantalum contents in the ranges 1–2 wt.% and 0.06–0.14 wt.% respectively. Increase in tungsten content increased the ductile-to-brittle transition temperature (DBTT), low cycle fatigue and creep strength of the steel, whereas the tensile strength was not changed significantly. Increase in tantalum content increased the DBTT and low cycle fatigue strength of the steel whereas the tensile and creep strength decreased. Detailed TEM investigations revealed enhanced microstructural stability of the steel against creep exposure on tungsten addition. The RAFM steel having 1.4 wt.% tungsten with 0.06 wt.% tantalum was found to possess optimum combination of impact, tensile, low cycle fatigue and creep properties and is considered for Indian-specific RAFM steel.

  9. Uni-dimensional double development HPTLC-densitometry method for simultaneous analysis of mangiferin and lupeol content in mango (Mangifera indica) pulp and peel during storage.

    Science.gov (United States)

    Jyotshna; Srivastava, Pooja; Killadi, Bharti; Shanker, Karuna

    2015-06-01

    Mango (Mangifera indica) fruit is one of the important commercial fruit crops of India. Similar to other tropical fruits it is also highly perishable in nature. During storage/ripening, changes in its physico-chemical quality parameters viz. firmness, titrable acidity, total soluble solid content (TSSC), carotenoids content, and other biochemicals are inevitable. A uni-dimensional double-development high-performance thin-layer chromatography (UDDD-HPTLC) method was developed for the real-time monitoring of mangiferin and lupeol in mango pulp and peel during storage. The quantitative determination of both compounds of different classes was achieved by densitometric HPTLC method. Silica gel 60F254 HPTLC plates and two solvent systems viz. toluene/EtOAC/MeOH and EtOAC/MeOH, respectively were used for optimum separation and selective evaluation. Densitometric quantitation of mangiferin was performed at 390nm, while lupeol at 610nm after post chromatographic derivatization. Validated method was used to real-time monitoring of mangiferin and lupeol content during storage in four Indian cultivars, e.g. Bombay green (Bgreen), Dashehari, Langra, and Chausa. Significant correlations (pacidity and TSSC with mangiferin and lupeol in pulp and peel during storage were also observed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Development, content validity, and cross-cultural adaptation of a patient-reported outcome measure for real-time symptom assessment in irritable bowel syndrome.

    Science.gov (United States)

    Vork, L; Keszthelyi, D; Mujagic, Z; Kruimel, J W; Leue, C; Pontén, I; Törnblom, H; Simrén, M; Albu-Soda, A; Aziz, Q; Corsetti, M; Holvoet, L; Tack, J; Rao, S S; van Os, J; Quetglas, E G; Drossman, D A; Masclee, A A M

    2018-03-01

    End-of-day questionnaires, which are considered the gold standard for assessing abdominal pain and other gastrointestinal (GI) symptoms in irritable bowel syndrome (IBS), are influenced by recall and ecological bias. The experience sampling method (ESM) is characterized by random and repeated assessments in the natural state and environment of a subject, and herewith overcomes these limitations. This report describes the development of a patient-reported outcome measure (PROM) based on the ESM principle, taking into account content validity and cross-cultural adaptation. Focus group interviews with IBS patients and expert meetings with international experts in the fields of neurogastroenterology & motility and pain were performed in order to select the items for the PROM. Forward-and-back translation and cognitive interviews were performed to adapt the instrument for the use in different countries and to assure on patients' understanding with the final items. Focus group interviews revealed 42 items, categorized into five domains: physical status, defecation, mood and psychological factors, context and environment, and nutrition and drug use. Experts reduced the number of items to 32 and cognitive interviewing after translation resulted in a few slight adjustments regarding linguistic issues, but not regarding content of the items. An ESM-based PROM, suitable for momentary assessment of IBS symptom patterns was developed, taking into account content validity and cross-cultural adaptation. This PROM will be implemented in a specifically designed smartphone application and further validation in a multicenter setting will follow. © 2017 John Wiley & Sons Ltd.

  11. Organic Tank Safety Project: development of a method to measure the equilibrium water content of Hanford organic tank wastes and demonstration of method on actual waste

    International Nuclear Information System (INIS)

    Scheele, R.D.; Bredt, P.R.; Sell, R.L.

    1996-09-01

    Some of Hanford's underground waste storage tanks contain Organic- bearing high level wastes that are high priority safety issues because of potentially hazardous chemical reactions of organics with inorganic oxidants in these wastes such as nitrates and nitrites. To ensure continued safe storage of these wastes, Westinghouse Hanford Company has placed affected tanks on the Organic Watch List and manages them under special rules. Because water content has been identified as the most efficient agent for preventing a propagating reaction and is an integral part of the criteria developed to ensure continued safe storage of Hanford's organic-bearing radioactive tank wastes, as part of the Organic Tank Safety Program the Pacific Northwest National Laboratory developed and demonstrated a simple and easily implemented procedure to determine the equilibrium water content of these potentially reactive wastes exposed to the range of water vapor pressures that might be experienced during the wastes' future storage. This work focused on the equilibrium water content and did not investigate the various factors such as at sign ventilation, tank surface area, and waste porosity that control the rate that the waste would come into equilibrium, with either the average Hanford water partial pressure 5.5 torr or other possible water partial pressures

  12. Organic Tank Safety Project: development of a method to measure the equilibrium water content of Hanford organic tank wastes and demonstration of method on actual waste

    Energy Technology Data Exchange (ETDEWEB)

    Scheele, R.D.; Bredt, P.R.; Sell, R.L.

    1996-09-01

    Some of Hanford`s underground waste storage tanks contain Organic- bearing high level wastes that are high priority safety issues because of potentially hazardous chemical reactions of organics with inorganic oxidants in these wastes such as nitrates and nitrites. To ensure continued safe storage of these wastes, Westinghouse Hanford Company has placed affected tanks on the Organic Watch List and manages them under special rules. Because water content has been identified as the most efficient agent for preventing a propagating reaction and is an integral part of the criteria developed to ensure continued safe storage of Hanford`s organic-bearing radioactive tank wastes, as part of the Organic Tank Safety Program the Pacific Northwest National Laboratory developed and demonstrated a simple and easily implemented procedure to determine the equilibrium water content of these potentially reactive wastes exposed to the range of water vapor pressures that might be experienced during the wastes` future storage. This work focused on the equilibrium water content and did not investigate the various factors such as @ ventilation, tank surface area, and waste porosity that control the rate that the waste would come into equilibrium, with either the average Hanford water partial pressure 5.5 torr or other possible water partial pressures.

  13. Development of a method for determination of metallic iron content within hot briquette iron (HBI for steelmaking

    Directory of Open Access Journals (Sweden)

    Morcali M.H.

    2016-01-01

    Full Text Available The growing use of metallic iron in metallurgy and industrial chemical applications requires a fast, easy and cheap method for the determination of metallic iron, not merely in recyclable materials, such as iron pellets, reduced iron mill scale dust, electric arc furnace dust and pig iron, but from hot briquette iron (HBI as well. This study investigates a new method for determination of metallic iron within HBI used for steel-making materials. The effects of reaction time, temperature, and stirring rate were studied. The concentration of iron was determined via Atomic Absorption Spectroscopy (AAS. After the optimization study, high-purity metallic iron powder (Sigma-Aldrich, PubChem Substance ID 24855469 was used to compare efficiencies and identify the optimum conditions; The present study was matched with international standard methods (BS ISO 5416:2006, IS 15774:2007. Results were consistent with certified values and metallic iron content could be determined within the 95% confidence level. The purposed method is easy, straightforward, and cheap.

  14. Exploring the effectiveness of obstetrics and gynecology information systems in hospitals of a developing country: A qualitative content analysis

    Directory of Open Access Journals (Sweden)

    Hassan Babamohamadi

    2016-07-01

    Full Text Available Obstetrics and gynecology information systems are designed to replace paper charts, interact with other clinical wards of hospital, and to better care for patients. This qualitative study was performed to explore the perception of midwives about the effectiveness of information systems. In this qualitative study, data were collected through semistructured and in-depth interviews and analyzed by content analysis and constant comparison method. Participants were 15 midwives from obstetrics and gynecology units of affiliated hospitals of Semnan University of Medical Sciences, Iran. Purposeful sampling method was used and continued until data saturation. The several themes that emerged from the interviews were divided into strength and weak points. Strength points included the facilitating the recording of information, reduction of costs and time, and the weakness points were repetition of tasks, low computer literacy of the staff, system restrictions on recording and editing, the unavailability of system and reduced the role of midwives in patient care. Midwives were faced with challenges in the use of information systems indicating the lack of quality of the information system. It seems that reinforcing strength points and resolving hardware and software problems can increase obstetrics and gynecology staff’s acceptance of this information system and reduce their cultural resistance toward it.

  15. Organization of radiation inspection for strip-mining development for ores with elevated content of natural radionuclides on the Karazhyra coal mine

    International Nuclear Information System (INIS)

    Lukashenko, S.N.; Subbotin, S.B.; Ajdarkhanov, A.O.; Medvedev, P.P.

    2003-01-01

    Due to existence of anomalous areas of ores with elevated content of natural radionuclides on the Karazhyra coal mine the project of its selective development was implemented. The project provides a set of measures on radiation safety. In the present paper the order of radiological operations organization and performance are shown, and methodical provision of these works is considered. Results of the preliminary radiological examination of the area, fulfilment the measures on mine works technology radiological safety, and strip-mining ores deposition are analyzed. The evaluations of natural radionuclides content with taking into account its influence on personnel during works fulfilment are made. The results of soil samples analysis are presented in the graphical form. The suggestions and recommendations on radiation monitoring improvement on the area are given

  16. Application of an automated natural language processing (NLP) workflow to enable federated search of external biomedical content in drug discovery and development.

    Science.gov (United States)

    McEntire, Robin; Szalkowski, Debbie; Butler, James; Kuo, Michelle S; Chang, Meiping; Chang, Man; Freeman, Darren; McQuay, Sarah; Patel, Jagruti; McGlashen, Michael; Cornell, Wendy D; Xu, Jinghai James

    2016-05-01

    External content sources such as MEDLINE(®), National Institutes of Health (NIH) grants and conference websites provide access to the latest breaking biomedical information, which can inform pharmaceutical and biotechnology company pipeline decisions. The value of the sites for industry, however, is limited by the use of the public internet, the limited synonyms, the rarity of batch searching capability and the disconnected nature of the sites. Fortunately, many sites now offer their content for download and we have developed an automated internal workflow that uses text mining and tailored ontologies for programmatic search and knowledge extraction. We believe such an efficient and secure approach provides a competitive advantage to companies needing access to the latest information for a range of use cases and complements manually curated commercial sources. Copyright © 2016. Published by Elsevier Ltd.

  17. Development of FT-NIR Models for the Simultaneous Estimation of Chlorophyll and Nitrogen Content in Fresh Apple (Malus Domestica Leaves

    Directory of Open Access Journals (Sweden)

    Elena Tamburini

    2015-01-01

    Full Text Available Agricultural practices determine the level of food production and, to great extent, the state of the global environment. During the last decades, the indiscriminate recourse to fertilizers as well as the nitrogen losses from land application have been recognized as serious issues of modern agriculture, globally contributing to nitrate pollution. The development of a reliable Near-Infra-Red Spectroscopy (NIRS-based method, for the simultaneous monitoring of nitrogen and chlorophyll in fresh apple (Malus domestica leaves, was investigated on a set of 133 samples, with the aim of estimating the nutritional and physiological status of trees, in real time, cheaply and non-destructively. By means of a FT (Fourier Transform-NIR instrument, Partial Least Squares (PLS regression models were developed, spanning a concentration range of 0.577%–0.817% for the total Kjeldahl nitrogen (TKN content (R2 = 0.983; SEC = 0.012; SEP = 0.028, and of 1.534–2.372 mg/g for the total chlorophyll content (R2 = 0.941; SEC = 0.132; SEP = 0.162. Chlorophyll-a and chlorophyll-b contents were also evaluated (R2 = 0.913; SEC = 0.076; SEP = 0.101 and R2 = 0.899; SEC = 0.059; SEP = 0.101, respectively. All calibration models were validated by means of 47 independent samples. The NIR approach allows a rapid evaluation of the nitrogen and chlorophyll contents, and may represent a useful tool for determining nutritional and physiological status of plants, in order to allow a correction of nutrition programs during the season.

  18. Melinda - A custom search engine that provides access to locally-developed content using the HL7 Infobutton standard.

    Science.gov (United States)

    Wan, Yik-Ki J; Staes, Catherine J

    2016-01-01

    Healthcare organizations use care pathways to standardize care, but once developed, adoption rates often remain low. One challenge for usage concerns clinicians' difficulty in accessing guidance when it is most needed. Although the HL7 'Infobutton Standard' allows clinicians easier access to external references, access to locally-developed resources often requires clinicians to deviate from their normal electronic health record (EHR) workflow to use another application. To address this gap between internal and external resources, we reviewed the literature and existing practices at the University of Utah Health Care. We identify the requirements to meet the needs of a healthcare enterprise and clinicians, describe the design and development of a prototype to aggregate both internal and external resources from within or outside the EHR, and evaluated strengths and limitations of the prototype. The system is functional but not implemented in a live EHR environment. We suggest next steps and enhancements.

  19. Development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention

    Science.gov (United States)

    Pureza, Janice R.; Fonseca, Rochele P.

    2017-01-01

    Introduction The importance of executive functions (EF) in childhood development, and their role as indicators of health, well-being, professional and academic success have been demonstrated by several studies in the literature. FE are cognitive processes that aim to control and manage behavior to achieve specific goal and included skills planning, inhibition, cognitive flexibility, (executive) attention and the central executive component of working memory (WM). In the context of education, the EF are crucial for continued learning and efficient academic performance due to their involvement in several components of the educational process. Objective The aim of this article was to describe the development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention. Methods The study involved seven specialists (four responsible for evaluating the program, and three involved in brainstorming), and was carried out in three stages: Background research: neuropsychology and education; Program development - author brainstorming and Evaluation by expert judges The goals, language and methods. Results CENA Program were considered adequate, attesting to its content validity as a school-based neuropsychological intervention. Conclusion Teacher training in school neuropsychology may be an important area for future investment and contribute to academic achievement and student development in the Brazilian education system. PMID:29213497

  20. Advertising Content

    OpenAIRE

    Simon P. Anderson; Régis Renault

    2002-01-01

    Empirical evidence suggests that most advertisements contain little direct informa- tion. Many do not mention prices. We analyze a firm'ss choice of advertising content and the information disclosed to consumers. A firm advertises only product informa- tion, price information, or both; and prefers to convey only limited product information if possible. Extending the "persuasion" game, we show that quality information takes precedence over price information and horizontal product information.T...

  1. Investigating the Impact of NGSS-Aligned Professional Development on PreK-3 Teachers' Science Content Knowledge and Pedagogy

    Science.gov (United States)

    Tuttle, Nicole; Kaderavek, Joan N.; Molitor, Scott; Czerniak, Charlene M.; Johnson-Whitt, Eugenia; Bloomquist, Debra; Namatovu, Winnifred; Wilson, Grant

    2016-01-01

    This pilot study investigates the impact of a 2-week professional development Summer Institute on PK-3 teachers' knowledge and practices. This Summer Institute is a component of [program], a large-scale early-childhood science project that aims to transform PK-3 science teaching. The mixed-methods study examined concept maps, lesson plans, and…

  2. Graphic Novels: A New Stress Mitigation Tool for Military Training: Developing Content for Hard-to-Reach Audiences.

    Science.gov (United States)

    Hourani, Laurel; Lambert, Shari; Peeler, Russ; Lane, Becky; Borst, Carrie

    2017-05-01

    This article describes the development of two graphic novels as a new approach to mental health communication and coping strategies for the Navy and Marine Corps. The novels are intended to capture the attention of the younger target audience and provide vital teaching messages to better prepare personnel for deployment to combat zones. The novels were developed based on embedding the principles of combat and operational stress control (COSC) into realistic and relatable characters, stories, and images. Approaches used for development included (a) basing storylines on real-life service members and the situations they face in combat and their personal lives; (b) partnering with COSC experts to embed teaching points; (c) ensuring technical accuracy through research and target audience reviews of the storyboard and artwork; (d) developing characters that are representative of the target audience, with varied jobs, ages, backgrounds, and professional concerns; and (e) designing artwork in a manner sensitive to training objectives and the psychological effects on readers. Because technical accuracy, realism, and sensitivity were noted as essential components of an effective graphic novel tool, focus-group research and review of author drafts by the target audience and technical experts are strongly recommended.

  3. Enhancing Primary Science Teaching: Interconnections of Content, Policy and Practice in a New Zealand Professional Learning and Development Programme

    Science.gov (United States)

    Sexton, Steven S.

    2018-01-01

    This paper reports on an ongoing professional learning and development (PLD) initiative in New Zealand. The Academy is designed to provide primary and intermediate classroom teachers with the knowledge, materials and support needed for effective delivery of "The New Zealand Curriculum's" science subject area. Specifically, this paper…

  4. Examining the Impact of Educational Technology Courses on Pre-Service Teachers' Development of Technological Pedagogical Content Knowledge

    Science.gov (United States)

    Hsu, Pi-Sui

    2012-01-01

    The purpose of this qualitative study was to examine the impact of educational technology courses on pre-service teachers' development of knowledge of technology integration in a teacher preparation program in the USA. The present study was conducted with eight pre-service teachers enrolled in the elementary teacher education program at a large…

  5. The Inclusion of Multiple Exceptional Gifted Students in Talent Development Programmes: Interaction Synthesis of Both Provision Form and Content

    Science.gov (United States)

    Gyarmathy, Éva; Senior, John

    2018-01-01

    Models of giftedness in the 21st century tend to describe talent as a social construct. Research now indicates that certain talented populations that are composed of multiple exceptional individuals are excluded from talent development programmes. Recognizing how well the environment best fits individual needs at particular key developmental…

  6. The Development of Inquiry Learning Materials to Complete Content Life System Organization in Junior High School Students

    Science.gov (United States)

    Mayasari, F.; Raharjo; Supardi, Z. A. I.

    2018-01-01

    This research aims to develop the material eligibility to complete the inquiry learning of student in the material organization system of junior high school students. Learning materials developed include syllabi, lesson plans, students’ textbook, worksheets, and learning achievement test. This research is the developmental research which employ Dick and Carey model to develop learning material. The experiment was done in Junior High School 4 Lamongan regency using One Group Pretest-Posttest Design. The data collection used validation, observation, achievement test, questionnaire administration, and documentation. Data analysis techniques used quantitative and qualitative descriptive.The results showed that the developed learning material was valid and can be used. Learning activity accomplished with good category, where student activities were observed. The aspects of attitudes were observed during the learning process are honest, responsible, and confident. Student learning achievement gained an average of 81, 85 in complete category, with N-Gain 0, 75 for a high category. The activities and student response to learning was very well categorized. Based on the results, this researcher concluded that the device classified as feasible of inquiry-based learning (valid, practical, and effective) system used on the material organization of junior high school students.

  7. Estimation of the Level of Cognitive Development of a Preschool Child Using the System of Situations with Mathematical Contents

    Science.gov (United States)

    Gorev, Pavel M.; Bichurina, Svetlana Y.; Yakupova, Rufiya M.; Khairova, Irina V.

    2016-01-01

    Cognitive development of personality can be considered as one of the key directions of preschool education presented in the world practice, where preschool programs are educational ones, and preschool education is the first level of the general education. Thereby the purpose of the research is to create a model of reliable estimation of cognitive…

  8. Effect of different cyanobacterial biomasses and their fractions with variable microcystin content on embryonal development of carp (Cyprinus carpio L.)

    Czech Academy of Sciences Publication Activity Database

    Palíková, M.; Krejčí, R.; Hilscherová, Klára; Babica, Pavel; Navrátil, S.; Kopp, R.; Bláha, Luděk

    2007-01-01

    Roč. 81, č. 3 (2007), s. 312-318 ISSN 0166-445X R&D Projects: GA AV ČR KJB6005411 Institutional research plan: CEZ:AV0Z60050516 Keywords : cyanobacterial biomass * embryonal development * common carp Subject RIV: EF - Botanics Impact factor: 2.975, year: 2007

  9. Cell number, tissue thickness and protein content as measures for development and variability in cultured neocortex explants

    NARCIS (Netherlands)

    de Jong, B. M.; Ruijter, J. M.

    1989-01-01

    The development of neuronal number, explant thickness and amount of protein was studied in several series of rat neocortex explants, cultured up to 21 days in vitro (DIV). In contrast to the dimensions of the explant, which rapidly stabilized, the amount of protein showed a prolonged increase with

  10. Combining Project-based Instruction, Earth Science Content, and GIS Technology in Teacher Professional Development: Is this Holistic Approach Sustainable?

    Science.gov (United States)

    Rubino-Hare, L.; Bloom, N.; Claesgens, J.; Fredrickson, K.; Henderson-Dahms, C.; Sample, J. C.

    2012-12-01

    From 2009-2011, with support from the National Science Foundation (ITEST, DRL-0929846) and Science Foundation Arizona (MSAG-0412-09), educators, geologists and geographers at Northern Arizona University (NAU) partnered to offer professional development for interdisciplinary teams of secondary and middle school teachers with a focus on project-based instruction (PBI) using geospatial technologies (GST). While participating in professional development teachers received support and were held accountable to NAU staff. They implemented activities and pedagogical strategies presented, increased knowledge, skills, and confidence teaching with project-based instruction integrating GST, and their students demonstrated learning gains. Changes in student understanding are only observed when teachers continue to implement change, so the question remained: did these changes in practice sustain after official project support ended? In order to determine what, if anything, teachers sustained from the professional development and the factors that promoted or hindered sustained use of teaching with GST and PBI, data were collected one to two years following the professional development. Research questions included a) what pedagogical practices did teachers sustain following the professional learning experiences? and b) what contexts were present in schools that supported or limited the use of geospatial technologies as a teaching and learning tool? Findings from this study indicate that teachers fall into three categories of sustaining implementation - reformed implementers, mechanical implementers and non-implementers. School context was less of a factor in level of implementation than teachers' beliefs and philosophy of teaching and teachers' understanding of technology integration (teaching with technology vs. teaching technology). Case studies of teacher experiences will be presented along with implications for future professional development.

  11. More than a House of Cards: Developing a Firm Foundation for Streaming Media and Consumer-Licensed Content in the Library

    Directory of Open Access Journals (Sweden)

    William Cross

    2016-09-01

    Full Text Available This article will introduce traditional library practice for licensing multimedia content and discuss the way that consumer-licensing and streaming services disrupt that practice. Sections II and III describe the statutory copyright regime designed by Congress to facilitate the socially-valuable work done by libraries and the impact of the move from ownership to licensed content. Collecting multimedia materials has always presented special legal challenges for libraries, particularly as licensed content has replaced the traditional practice of purchasing and circulation based on the first sale doctrine. These issues have grown even more complex as streaming services like Netflix and Amazon and video game downloads through services like Steam have come to dominate the landscape. Section IV will describe the way that consumer-licensed materials, which not only remove the ownership that undergirds library practice, but also the ability to negotiate for library use, imperil the congressionally-designed balance. Section V will present a path forward for libraries to develop robust, cutting-edge collections that reflect a sophisticated understanding of the contractual and copyright issues at play.

  12. Development and Validation of a Near-Infrared Spectroscopy Method for the Prediction of Acrylamide Content in French-Fried Potato.

    Science.gov (United States)

    Adedipe, Oluwatosin E; Johanningsmeier, Suzanne D; Truong, Van-Den; Yencho, G Craig

    2016-03-02

    This study investigated the ability of near-infrared spectroscopy (NIRS) to predict acrylamide content in French-fried potato. Potato flour spiked with acrylamide (50-8000 μg/kg) was used to determine if acrylamide could be accurately predicted in a potato matrix. French fries produced with various pretreatments and cook times (n = 84) and obtained from quick-service restaurants (n = 64) were used for model development and validation. Acrylamide was quantified using gas chromatography-mass spectrometry, and reflectance spectra (400-2500 nm) of each freeze-dried sample were captured on a Foss XDS Rapid Content Analyzer-NIR spectrometer. Partial least-squares (PLS) discriminant analysis and PLS regression modeling demonstrated that NIRS could accurately detect acrylamide content as low as 50 μg/kg in the model potato matrix. Prediction errors of 135 μg/kg (R(2) = 0.98) and 255 μg/kg (R(2) = 0.93) were achieved with the best PLS models for acrylamide prediction in Russet Norkotah French-fried potato and multiple samples of unknown varieties, respectively. The findings indicate that NIRS can be used as a screening tool in potato breeding and potato processing research to reduce acrylamide in the food supply.

  13. LOGO programming contents for supporting mathematical concept development : promotion of the verbalization and imaging of figure concepts

    OpenAIRE

    杉野, 裕子

    2014-01-01

    I have been studying to show the importance of adopting a programming in the mathematical education and developed the LOGO teaching materials which is made good use of in the field of Euclidean geometry, in order to improve understanding and learning figure concepts. The present article offers a theoretical framework with consistency about my study and also new programming materials in which I embody my theory. I consider logically the system of mathematical expression with computers and espe...

  14. Linking Student Achievement and Teacher Science Content Knowledge about Climate Change: Ensuring the Nations 3 Million Teachers Understand the Science through an Electronic Professional Development System

    Science.gov (United States)

    Niepold, F.; Byers, A.

    2009-12-01

    The scientific complexities of global climate change, with wide-ranging economic and social significance, create an intellectual challenge that mandates greater public understanding of climate change research and the concurrent ability to make informed decisions. The critical need for an engaged, science literate public has been repeatedly emphasized by multi-disciplinary entities like the Intergovernmental Panel on Climate Change (IPCC), the National Academies (Rising Above the Gathering Storm report), and the interagency group responsible for the recently updated Climate Literacy: The Essential Principles of Climate Science. There is a clear need for an American public that is climate literate and for K-12 teachers confident in teaching relevant science content. A key goal in the creation of a climate literate society is to enhance teachers’ knowledge of global climate change through a national, scalable, and sustainable professional development system, using compelling climate science data and resources to stimulate inquiry-based student interest in science, technology, engineering, and mathematics (STEM). This session will explore innovative e-learning technologies to address the limitations of one-time, face-to-face workshops, thereby adding significant sustainability and scalability. The resources developed will help teachers sift through the vast volume of global climate change information and provide research-based, high-quality science content and pedagogical information to help teachers effectively teach their students about the complex issues surrounding global climate change. The Learning Center is NSTA's e-professional development portal to help the nations teachers and informal educators learn about the scientific complexities of global climate change through research-based techniques and is proven to significantly improve teacher science content knowledge.

  15. Development and evaluation of the content validity, practicability and feasibility of the Innovative dementia-oriented Assessment system for challenging behaviour in residents with dementia.

    Science.gov (United States)

    Halek, Margareta; Holle, Daniela; Bartholomeyczik, Sabine

    2017-08-14

    One of the most difficult issues for care staff is the manifestation of challenging behaviour among residents with dementia. The first step in managing this type of behaviour is analysing its triggers. A structured assessment instrument can facilitate this process and may improve carers' management of the situation. This paper describes the development of an instrument designed for this purpose and an evaluation of its content validity and its feasibility and practicability in nursing homes. The development process and evaluation of the content validity were based on Lynn's methodology (1998). A literature review (steps 1 + 2) provided the theoretical framework for the instrument and for item formation. Ten experts (step 3) evaluated the first version of the instrument (the Innovative dementia-oriented Assessment (IdA®)) regarding its relevance, clarity, meaningfulness and completeness; content validity indices at the scale-level (S-CVI) and item-level (I-CVI) were calculated. Health care workers (step 4) evaluated the second version in a workshop. Finally, the instrument was introduced to 17 units in 11 nursing homes in a field study (step 5), and 60 care staff members assessed its practicability and feasibility. The IdA® used the need-driven dementia-compromised behaviour (NDB) model as a theoretical framework. The literature review and expert-based panel supported the content validity of the IdA®. At the item level, 77% of the ratings had a CVI greater than or equal to 0.78. The majority of the question-ratings (84%, n = 154) and answer-ratings (69%, n = 122) showed valid results, with none below 0.50. The health care workers confirmed the understandability, completeness and plausibility of the IdA®. Steps 3 and 4 led to further item clarification. The carers in the study considered the instrument helpful for reflecting challenging behaviour and beneficial for the care of residents with dementia. Negative ratings referred to the time required and the

  16. Development of a multidisciplinary method for mapping spatial extent and C-content of tropical ombrotrophic peatlands

    Science.gov (United States)

    Illés, Gábor; Kristijono, Agus; Pfeifer, Norbert; Pásztor, László; Shandhyavitri, Ari; Szatmári, Gábor; Sutikno, Sigit; Molnár, Gábor; László, Péter; Árvai, Mátyás; Mészáros, János; Koós, Sándor; Bakacsi, Zsófia; Takács, Katalin; Király, Géza; Székely, Balázs

    2017-04-01

    One of the world's most worrying environmental problems is the peat land CO2 emission problem of Indonesia: peat lands developed during the Quaternary are now under strong human influence; the artificial lowering of the natural water table leads to rapid drying and compaction of the peat layer, which then becomes vulnerable to subsurface fire. The emitted CO2 of this process is assessed to be 0.5 billion tonnes from Indonesia that is slightly higher than total emission of e.g. United Kingdom in 2014 (0.42 billion tonnes). To cope with the problem it is inevitable to assess the extents of peat lands and volumetric estimation of the potentially affected layers. Methods suitable for mapping of the peat lands (current situation and as far as possible retrospectively), thickness determination and partly thickness estimation of the peat layer are integrated in an advanced geostatistical approach building upon geomorphic, ecological, remote sensing, and geophysical methods to provide information on peat matrix attributes such as peat thickness of organo-mineral horizons between peat and underlying substrate, the presence of buried wood, buttressed trees or tip-up pools and soil type. In order to cope with the problem, our research group is developing a multidisciplinary methodology making use of our experience in soil science, GIS, remote sensing for forestry and ecology, geomorphometry, geophysics, LiDAR remote sensing, parameter estimation and geostatistical methods. The methodology is based largely on GIS data integration, but also applies technologies of 'big data' processing. Our integrative attitude ensures the holistic consideration of the problem, analyzing its origins, temporal development and varying spatial extent, its subprocesses in a multi-scale, inter- and transdisciplinary approach. At the same time practical problems, feasibility, costs, and human resource need consideration in order to design a viable solution. In the development of the solution

  17. Assessing the complexity of interventions within systematic reviews: development, content and use of a new tool (iCAT_SR

    Directory of Open Access Journals (Sweden)

    Simon Lewin

    2017-04-01

    Full Text Available Abstract Background Health interventions fall along a spectrum from simple to more complex. There is wide interest in methods for reviewing ‘complex interventions’, but few transparent approaches for assessing intervention complexity in systematic reviews. Such assessments may assist review authors in, for example, systematically describing interventions and developing logic models. This paper describes the development and application of the intervention Complexity Assessment Tool for Systematic Reviews (iCAT_SR, a new tool to assess and categorise levels of intervention complexity in systematic reviews. Methods We developed the iCAT_SR by adapting and extending an existing complexity assessment tool for randomized trials. We undertook this adaptation using a consensus approach in which possible complexity dimensions were circulated for feedback to a panel of methodologists with expertise in complex interventions and systematic reviews. Based on these inputs, we developed a draft version of the tool. We then invited a second round of feedback from the panel and a wider group of systematic reviewers. This informed further refinement of the tool. Results The tool comprises ten dimensions: (1 the number of active components in the intervention; (2 the number of behaviours of recipients to which the intervention is directed; (3 the range and number of organizational levels targeted by the intervention; (4 the degree of tailoring intended or flexibility permitted across sites or individuals in applying or implementing the intervention; (5 the level of skill required by those delivering the intervention; (6 the level of skill required by those receiving the intervention; (7 the degree of interaction between intervention components; (8 the degree to which the effects of the intervention are context dependent; (9 the degree to which the effects of the interventions are changed by recipient or provider factors; (10 and the nature of the causal

  18. METHODS OF CONTENTS CURATOR

    Directory of Open Access Journals (Sweden)

    V. Kukharenko

    2013-03-01

    Full Text Available Content curated - a new activity (started in 2008 qualified network users with process large amounts of information to represent her social network users. To prepare content curators developed 7 weeks distance course, which examines the functions, methods and tools curator. Courses showed a significant relationship success learning on the availability of advanced personal learning environment and the ability to process and analyze information.

  19. Reinforcing Spirals Model: Conceptualizing the Relationship Between Media Content Exposure and the Development and Maintenance of Attitudes

    Science.gov (United States)

    Slater, Michael D.

    2014-01-01

    The Reinforcing Spirals Model (RSM, Citation Withheld) has two primary purposes. First, the RSM provides a general framework for conceptualizing media use as part of a dynamic, endogenous process combining selective exposure and media effects that may be drawn on by theorists concerned with a variety of social processes and effects. Second, the RSM utilizes a systems-theory perspective to describe how patterns of mediated and interpersonal communication contribute to the development and maintenance of social identities and ideology as well as more transient attitudes and related behaviors, and how those outcomes may influence subsequent media use. The RSM suggests contingencies that may lead to homeostasis or encourage certain individuals or groups to extreme polarization of such attitudes. In addition, the RSM proposes social cognitive mechanisms that may be responsible for attitude maintenance and reinforcement. This article discusses empirical progress in testing the model, addresses misconceptions that have arisen, and provides elaborated illustrations of the model. The article also identifies potentially fruitful directions for further conceptual development and empirical testing of the RSM. PMID:26366124

  20. Phytosterol content and the campesterol:sitosterol ratio influence cotton fiber development: role of phytosterols in cell elongation.

    Science.gov (United States)

    Deng, Shasha; Wei, Ting; Tan, Kunling; Hu, Mingyu; Li, Fang; Zhai, Yunlan; Ye, Shue; Xiao, Yuehua; Hou, Lei; Pei, Yan; Luo, Ming

    2016-02-01

    Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model for the study of plant cell elongation and cell wall biogenesis. The role of phytosterols in fiber growth was investigated by treating the fibers with tridemorph, a sterol biosynthetic inhibitor. The inhibition of phytosterol biosynthesis resulted in an apparent suppression of fiber elongation in vitro or in planta. The determination of phytosterol quantity indicated that sitosterol and campesterol were the major phytosterols in cotton fibers; moreover, higher concentrations of these phytosterols were observed during the period of rapid elongation of fibers. Furthermore, the decrease and increase in campesterol:sitosterol ratio was associated with the increase and decease in speed of elongation, respectively, during the elongation stage. The increase in the ratio was associated with the transition from cell elongation to secondary cell wall synthesis. In addition, a number of phytosterol biosynthetic genes were down-regulated in the short fibers of ligon lintless-1 mutant, compared to its near-isogenic wild-type TM-1. These results demonstrated that phytosterols play a crucial role in cotton fiber development, and particularly in fiber elongation.

  1. Reinforcing Spirals Model: Conceptualizing the Relationship Between Media Content Exposure and the Development and Maintenance of Attitudes.

    Science.gov (United States)

    Slater, Michael D

    2015-07-01

    The Reinforcing Spirals Model (RSM, Citation Withheld) has two primary purposes. First, the RSM provides a general framework for conceptualizing media use as part of a dynamic, endogenous process combining selective exposure and media effects that may be drawn on by theorists concerned with a variety of social processes and effects. Second, the RSM utilizes a systems-theory perspective to describe how patterns of mediated and interpersonal communication contribute to the development and maintenance of social identities and ideology as well as more transient attitudes and related behaviors, and how those outcomes may influence subsequent media use. The RSM suggests contingencies that may lead to homeostasis or encourage certain individuals or groups to extreme polarization of such attitudes. In addition, the RSM proposes social cognitive mechanisms that may be responsible for attitude maintenance and reinforcement. This article discusses empirical progress in testing the model, addresses misconceptions that have arisen, and provides elaborated illustrations of the model. The article also identifies potentially fruitful directions for further conceptual development and empirical testing of the RSM.

  2. A 67-Item Stress Resilience item bank showing high content validity was developed in a psychosomatic sample.

    Science.gov (United States)

    Obbarius, Nina; Fischer, Felix; Obbarius, Alexander; Nolte, Sandra; Liegl, Gregor; Rose, Matthias

    2018-04-10

    To develop the first item bank to measure Stress Resilience (SR) in clinical populations. Qualitative item development resulted in an initial pool of 131 items covering a broad theoretical SR concept. These items were tested in n=521 patients at a psychosomatic outpatient clinic. Exploratory and Confirmatory Factor Analysis (CFA), as well as other state-of-the-art item analyses and IRT were used for item evaluation and calibration of the final item bank. Out of the initial item pool of 131 items, we excluded 64 items (54 factor loading .3, 2 non-discriminative Item Response Curves, 4 Differential Item Functioning). The final set of 67 items indicated sufficient model fit in CFA and IRT analyses. Additionally, a 10-item short form with high measurement precision (SE≤.32 in a theta range between -1.8 and +1.5) was derived. Both the SR item bank and the SR short form were highly correlated with an existing static legacy tool (Connor-Davidson Resilience Scale). The final SR item bank and 10-item short form showed good psychometric properties. When further validated, they will be ready to be used within a framework of Computer-Adaptive Tests for a comprehensive assessment of the Stress-Construct. Copyright © 2018. Published by Elsevier Inc.

  3. The application of systematic analysis to the development for maintenance staffs training contents in Nuclear Power Station

    International Nuclear Information System (INIS)

    Ishida, Takahisa; Maruo, Tadashi; Kurokawa, Kazuya

    2005-01-01

    To survive the tide of electric power industry deregulation, actions for streamlining our operations must be compatible with safe of plant operation. With regard to the human resource issue, retirement of first line engineers who developed their practical technical skills through the process of experiencing numerous problems or plant construction can raise concerns regarding a decline in our engineering abilities. Under these circumstances, to prepare sophisticated maintenance engineers, training programs must be optimized by considering the most effective and efficient method and material. Despite the IAEA's SAT (Systematic Approach to Training) method being widely applied to train nuclear power plants operators, there are few reports that it is applied to maintenance engineers. This paper will discuss our attempt to introduce more effective and efficient training for maintenance engineers, as well as refer to the SAT method to analyze the education program as a whole. (author)

  4. The influence of sand content on swelling pressures and structure developed in statically compacted Na-bentonite

    International Nuclear Information System (INIS)

    Gray, M.N.; Cheung, S.C.H.; Dixon, D.A.

    1984-09-01

    A laboratory investigation of the vertical and lateral swelling pressures developed in statically compacted, air-dry specimens of sodium (Na)-bentonite:silica sand mixtures as they are saturated in confined conditions with double-distilled, deionized water is described. The results are interpreted with the aid of observations of the compacted soil structures made in a scanning electron microscope. It is shown that the sand acts as an inert filler material and vertical swelling pressures are controlled by a parameter termed the effective clay dry density (qsub(c)). A limiting value of qsub(c) exists below which vertical and lateral swelling pressures do not differ and are theoretically predictable. Above this value, vertical pressures exceed lateral ones. This is related to a change from an isotropic to an anisotropic soil fabric as qsub(c) is increased above the limiting value

  5. Development of diamond thin film-based alpha particle detectors for online assay of plutonium content in corrosive liquid medium

    International Nuclear Information System (INIS)

    Nuwad, J.; Jain, Dheeraj; Manoj, N.; Sudarsan, V.; Panja, S.; Dhami, P.S.

    2014-01-01

    In the present work, diamond thin films were prepared using microwave plasma chemical vapor deposition (MPCVD) method and characterized using XRD, OES, SEM, Raman spectroscopy and I-V techniques. These films were subjected to annealing and chemical cleaning for further improving the film quality. Surface metallization was obtained by gold deposition using PVD. These films were configured in semiconductor-insulator-metal heterostructure and mounted in SS shells. Gold coated growth surface (detector's active area) was sealed by chemical resistant sealing. Suitable bias was applied between the front and back electrical contacts to enable charge collection generated upon alpha particle interaction with diamond. The photograph of developed detector in the lab is shown

  6. Development of Fourier transform mid-infrared calibrations to predict acetone, β-hydroxybutyrate, and citrate contents in bovine milk through a European dairy network.

    Science.gov (United States)

    Grelet, C; Bastin, C; Gelé, M; Davière, J-B; Johan, M; Werner, A; Reding, R; Fernandez Pierna, J A; Colinet, F G; Dardenne, P; Gengler, N; Soyeurt, H; Dehareng, F

    2016-06-01

    To manage negative energy balance and ketosis in dairy farms, rapid and cost-effective detection is needed. Among the milk biomarkers that could be useful for this purpose, acetone and β-hydroxybutyrate (BHB) have been proved as molecules of interest regarding ketosis and citrate was recently identified as an early indicator of negative energy balance. Because Fourier transform mid-infrared spectrometry can provide rapid and cost-effective predictions of milk composition, the objective of this study was to evaluate the ability of this technology to predict these biomarkers in milk. Milk samples were collected in commercial and experimental farms in Luxembourg, France, and Germany. Acetone, BHB, and citrate contents were determined by flow injection analysis. Milk mid-infrared spectra were recorded and standardized for all samples. After edits, a total of 548 samples were used in the calibration and validation data sets for acetone, 558 for BHB, and 506 for citrate. Acetone content ranged from 0.020 to 3.355mmol/L with an average of 0.103mmol/L; BHB content ranged from 0.045 to 1.596mmol/L with an average of 0.215mmol/L; and citrate content ranged from 3.88 to 16.12mmol/L with an average of 9.04mmol/L. Acetone and BHB contents were log-transformed and a part of the samples with low values was randomly excluded to approach a normal distribution. The 3 edited data sets were then randomly divided into a calibration data set (3/4 of the samples) and a validation data set (1/4 of the samples). Prediction equations were developed using partial least square regression. The coefficient of determination (R(2)) of cross-validation was 0.73 for acetone, 0.71 for BHB, and 0.90 for citrate with root mean square error of 0.248, 0.109, and 0.70mmol/L, respectively. Finally, the external validation was performed and R(2) obtained were 0.67 for acetone, 0.63 for BHB, and 0.86 for citrate, with respective root mean square error of validation of 0.196, 0.083, and 0.76mmol/L. Although

  7. Development and identification of SSR markers associated with starch properties and β-carotene content in the storage root of sweet potato (Ipomoea batatas L.

    Directory of Open Access Journals (Sweden)

    Kai eZhang

    2016-03-01

    Full Text Available Sweet potato (Ipomoea batatas L. is a nutritious food crop and, based on the high starch content of its storage root, a potential bioethanol feedstock. Enhancing the nutritional value and starch quantity of storage roots are important goals of sweet potato breeding programs aimed at developing improved varieties for direct consumption, processing, and industrial uses. However, developing improved lines of sweet potato is challenging due to the genetic complexity of this plant and the lack of genome information. Short sequence repeat (SSR markers are powerful molecular tools for tracking important loci in crops and for molecular-based breeding strategies; however, few SSR markers and marker-trait associations have hitherto been identified in sweet potato. In this study, we identified 1,824 SSRs by using a de novo assembly of publicly available ESTs and mRNAs in sweet potato, and designed 1,476 primer pairs based on SSR-containing sequences. We mapped 214 pairs of primers in a natural population comprised of 239 germplasms, and identified 1,278 alleles with an average of 5.972 alleles per locus and a major allele frequency of 0.7702. Population structure analysis revealed two subpopulations in this panel of germplasms, and phenotypic characterization demonstrated that this panel is suitable for association mapping of starch-related traits. We identified 32, 16, and 17 SSR markers associated with starch content, β-carotene content, and starch composition in the storage root, respectively, using association analysis and further evaluation of a subset of sweet potato genotypes with various characteristics. The SSR markers identified here can be used to select varieties with desired traits and to investigate the genetic mechanism underlying starch and carotenoid formation in the starchy roots of sweet potato.

  8. Development of Technological and Pedagogical Content Knowledge of the Chemistry by Teachers in Training Through the Reflection of PaP-eRs and Videos

    Directory of Open Access Journals (Sweden)

    Boris Fernando Candela

    2018-01-01

    Full Text Available This article described how trainee teachers identified and developed some elements of the Technological and Pedagogical Knowledge of Chemistry Content (CTPC, along the course of educational and pedagogical context by "reflective orientation". The methodological perspective was qualitative by case study, which was configured by two interwoven areas of reflection, namely: (a reflecting on the opinions of experts about the teaching of a content, through the readings proposed in the training programs; and (b reflecting on the teaching carried out by experienced teachers through case videos and the Repertoire of Professional and Pedagogical Experiences (PaP-eRs. This heuristic reduced the complexity of teaching in a manageable story located in a specific context, so that teachers could identify and reflect on their theories about the teaching and learning of chemistry. This study showed that teachers in training identified and developed the following elements of the CTPC of chemistry: general pedagogy, language as a learning tool, difficulties and alternative conceptions, knowledge of technology as an instrument to represent the contents and manage the chemistry classroom, and the formative evaluation. Definitely, the reflection of the critical events of the PaP-eRs and videos of cases was considered an appropriate heuristic that allowed the future teachers to articulate the knowledge coming from the literature in education in chemistry, with the virtual experiences of teaching-learning of a real context. Of course, this reflection was mediated by reading, discussing and reflecting on the intelligent actions of an exemplary teacher when guiding singular students from a sociocultural perspective, with the purpose of beginning to refine their theories of teaching and learning chemistry.

  9. A Community College Instructor's Reflective Journey Toward Developing Pedagogical Content Knowledge for Nature of Science in a Non-majors Undergraduate Biology Course

    Science.gov (United States)

    Krajewski, Sarah J.; Schwartz, Renee

    2014-08-01

    Research supports an explicit-reflective approach to teaching about nature of science (NOS), but little is reported on teachers' journeys as they attempt to integrate NOS into everyday lessons. This participatory action research paper reports the challenges and successes encountered by an in-service teacher, Sarah, implementing NOS for the first time throughout four units of a community college biology course (genetics, molecular biology, evolution, and ecology). Through the action research cycles of planning, implementing, and reflecting, Sarah identified areas of challenge and success. This paper reports emergent themes that assisted her in successfully embedding NOS within the science content. Data include weekly lesson plans and pre/post reflective journaling before and after each lesson of this lecture/lab combination class that met twice a week. This course was taught back to back semesters, and this study is based on the results of a year-long process. Developing pedagogical content knowledge (PCK) for NOS involves coming to understand the overlaps and connections between NOS, other science subject matter, pedagogical strategies, and student learning. Sarah found that through action research she was able to grow and assimilate her understanding of NOS within the biology content she was teaching. A shift in orientation toward teaching products of science to teaching science processes was a necessary shift for NOS pedagogical success. This process enabled Sarah's development of PCK for NOS. As a practical example of putting research-based instructional recommendations into practice, this study may be very useful for other teachers who are learning to teach NOS.

  10. Development and Identification of SSR Markers Associated with Starch Properties and β-Carotene Content in the Storage Root of Sweet Potato (Ipomoea batatas L.).

    Science.gov (United States)

    Zhang, Kai; Wu, Zhengdan; Tang, Daobin; Lv, Changwen; Luo, Kai; Zhao, Yong; Liu, Xun; Huang, Yuanxin; Wang, Jichun

    2016-01-01

    Sweet potato (Ipomoea batatas L.) is a nutritious food crop and, based on the high starch content of its storage root, a potential bioethanol feedstock. Enhancing the nutritional value and starch quantity of storage roots are important goals of sweet potato breeding programs aimed at developing improved varieties for direct consumption, processing, and industrial uses. However, developing improved lines of sweet potato is challenging due to the genetic complexity of this plant and the lack of genome information. Short sequence repeat (SSR) markers are powerful molecular tools for tracking important loci in crops and for molecular-based breeding strategies; however, few SSR markers and marker-trait associations have hitherto been identified in sweet potato. In this study, we identified 1824 SSRs by using a de novo assembly of publicly available ESTs and mRNAs in sweet potato, and designed 1476 primer pairs based on SSR-containing sequences. We mapped 214 pairs of primers in a natural population comprised of 239 germplasms, and identified 1278 alleles with an average of 5.972 alleles per locus and a major allele frequency of 0.7702. Population structure analysis revealed two subpopulations in this panel of germplasms, and phenotypic characterization demonstrated that this panel is suitable for association mapping of starch-related traits. We identified 32, 16, and 17 SSR markers associated with starch content, β-carotene content, and starch composition in the storage root, respectively, using association analysis and further evaluation of a subset of sweet potato genotypes with various characteristics. The SSR markers identified here can be used to select varieties with desired traits and to investigate the genetic mechanism underlying starch and carotenoid formation in the starchy roots of sweet potato.

  11. Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines with optimized choline content.

    Science.gov (United States)

    Kuwae, Shinobu; Miyakawa, Ichiko; Doi, Tomohiro

    2018-01-11

    A chemically defined platform basal medium and feed media were developed using a single Chinese hamster ovary (CHO) cell line that produces a monoclonal antibody (mAb). Cell line A, which showed a peak viable cell density of 5.9 × 10 6  cells/mL and a final mAb titer of 0.5 g/L in batch culture, was selected for the platform media development. Stoichiometrically balanced feed media were developed using glucose as an indicator of cell metabolism to determine the feed rates of all other nutrients. A fed-batch culture of cell line A using the platform fed-batch medium yielded a 6.4 g/L mAb titer, which was 12-fold higher than that of the batch culture. To examine the applicability of the platform basal medium and feed media, three other cell lines (A16, B, and C) that produce mAbs were cultured using the platform fed-batch medium, and they yielded mAb titers of 8.4, 3.3, and 6.2 g/L, respectively. The peak viable cell densities of the three cell lines ranged from 1.3 × 10 7 to 1.8 × 10 7  cells/mL. These results show that the nutritionally balanced fed-batch medium and feeds worked well for other cell lines. During the medium development, we found that choline limitation caused a lower cell viability, a lower mAb titer, a higher mAb aggregate content, and a higher mannose-5 content. The optimal choline chloride to glucose ratio for the CHO cell fed-batch culture was determined. Our platform basal medium and feed media will shorten the medium-development time for mAb-producing cell lines.

  12. The order and priority of research and design method application within an assistive technology new product development process: a summative content analysis of 20 case studies.

    Science.gov (United States)

    Torrens, George Edward

    2018-01-01

    Summative content analysis was used to define methods and heuristics from each case study. The review process was in two parts: (1) A literature review to identify conventional research methods and (2) a summative content analysis of published case studies, based on the identified methods and heuristics to suggest an order and priority of where and when were used. Over 200 research and design methods and design heuristics were identified. From the review of the 20 case studies 42 were identified as being applied. The majority of methods and heuristics were applied in phase two, market choice. There appeared a disparity between the limited numbers of methods frequently used, under 10 within the 20 case studies, when hundreds were available. Implications for Rehabilitation The communication highlights a number of issues that have implication for those involved in assistive technology new product development: •The study defined over 200 well-established research and design methods and design heuristics that are available for use by those who specify and design assistive technology products, which provide a comprehensive reference list for practitioners in the field; •The review within the study suggests only a limited number of research and design methods are regularly used by industrial design focused assistive technology new product developers; and, •Debate is required within the practitioners working in this field to reflect on how a wider range of potentially more effective methods and heuristics may be incorporated into daily working practice.

  13. Development of a Rating Tool for Mobile Cancer Apps: Information Analysis and Formal and Content-Related Evaluation of Selected Cancer Apps.

    Science.gov (United States)

    Böhme, Cathleen; von Osthoff, Marc Baron; Frey, Katrin; Hübner, Jutta

    2017-08-17

    Mobile apps are offered in large numbers and have different qualities. The aim of this article was to develop a rating tool based on formal and content-related criteria for the assessment of cancer apps and to test its applicability on apps. After a thorough analysis of the literature, we developed a specific rating tool for cancer apps based on the MARS (mobile app rating system) and a rating tool for cancer websites. This instrument was applied to apps freely available in stores and focusing on some cancer topic. Ten apps were rated on the basis of 22 criteria. Sixty percent of the apps (6/10) were rated poor and insufficient. The rating by different scientists was homogenous. The good apps had reliable sources were regularly updated and had a concrete intent/purpose in their app description. In contrast, the apps that were rated poor had no distinction of scientific content and advertisement. In some cases, there was no imprint to identify the provider. As apps of poor quality can give misinformation and lead to wrong treatment decisions, efforts have to be made to increase usage of high-quality apps. Certification would help cancer patients to identify reliable apps, yet acceptance of a certification system must be backed up.

  14. Development of macaronic Hindi-English ‘Hinglish’ text message content for a coronary heart disease secondary prevention programme

    Science.gov (United States)

    Thakkar, Jay; Karthikeyan, Ganesan; Purohit, Gaurav; Thakkar, Swetha; Sharma, Jitender; Verma, Sunilkumar; Parakh, Neeraj; Seth, Sandeep; Mishra, Sundeep; Yadav, Rakesh; Singh, Sandeep; Joshi, Rohina; Thiagalingam, Aravinda; Chow, Clara K; Redfern, Julie

    2016-01-01

    Background Coronary heart disease (CHD) is a leading cause of morbidity and mortality in India. Text message based prevention programs have demonstrated reduction in cardiovascular risk factors among patients with CHD in selected populations. Customisation is important as behaviour change is influenced by culture and linguistic context. Objectives To customise a mobile phone text message program supporting behaviour and treatment adherence in CHD for delivery in North India. Methods We used an iterative process with mixed methods involving three phases: (1) Initial translation, (2) Review and incorporation of feedback including review by cardiologists in India to assess alignment with local guidelines and by consumers on perceived utility and clarity and (3) Pilot testing of message management software. Results Messages were translated in three ways: symmetrical translation, asymmetrical translation and substitution. Feedback from cardiologists and 25 patients was incorporated to develop the final bank. Patients reported Hinglish messages were easy to understand (93%) and useful (78%). The software located in Australia successfully delivered messages to participants based in Delhi-surrounds (India). Conclusions Our process for customisation of a text message program considered cultural, linguistic and the medical context of potential participants. This is important in optimising intervention fidelity across populations enabling examination of the generalisability of text message programs across populations. We also demonstrated the customised program was acceptable to patients in India and that a centralised cross-country delivery model was feasible. This process could be used as a guide for other groups seeking to customise their programs. Trial registration number TEXTMEDS Australia (Parent study)—ACTRN 12613000793718. PMID:27752288

  15. Development of a data-processing method based on Bayesian k-means clustering to discriminate aneugens and clastogens in a high-content micronucleus assay.

    Science.gov (United States)

    Huang, Z H; Li, N; Rao, K F; Liu, C T; Huang, Y; Ma, M; Wang, Z J

    2018-03-01

    Genotoxicants can be identified as aneugens and clastogens through a micronucleus (MN) assay. The current high-content screening-based MN assays usually discriminate an aneugen from a clastogen based on only one parameter, such as the MN size, intensity, or morphology, which yields low accuracies (70-84%) because each of these parameters may contribute to the results. Therefore, the development of an algorithm that can synthesize high-dimensionality data to attain comparative results is important. To improve the automation and accuracy of detection using the current parameter-based mode of action (MoA), the MN MoA signatures of 20 chemicals were systematically recruited in this study to develop an algorithm. The results of the algorithm showed very good agreement (93.58%) between the prediction and reality, indicating that the proposed algorithm is a validated analytical platform for the rapid and objective acquisition of genotoxic MoA messages.

  16. Variation in psychosocial influences according to the dimensions and content of children's unusual experiences: potential routes for the development of targeted interventions.

    Science.gov (United States)

    Ruffell, Tamatha; Azis, Matilda; Hassanali, Nedah; Ames, Catherine; Browning, Sophie; Bracegirdle, Karen; Corrigall, Richard; Laurens, Kristin R; Hirsch, Colette; Kuipers, Elizabeth; Maddox, Lucy; Jolley, Suzanne

    2016-03-01

    The psychosocial processes implicated in the development and maintenance of psychosis differ according to both the dimensional attributes (conviction, frequency, associated distress, adverse life impact) and the content or type (e.g. grandiosity, hallucinations, paranoia) of the psychotic symptoms experienced. This has informed the development of 'targeted' cognitive behavioural therapy for psychosis (CBTp): interventions focusing on specific psychological processes in the context of particular symptom presentations. In adults, larger effect sizes for change in primary outcomes are typically reported in trials of targeted interventions, compared to those for trials of generic CBTp approaches with multiple therapeutic foci. We set out to test the theoretical basis for developing targeted CBTp interventions for young people with distressing psychotic-like, or unusual, experiences (UEs). We investigated variations in the psychosocial processes previously associated with self-reported UE severity (reasoning, negative life events, emotional problems) according to UE dimensional attributes and content/type (using an established five-factor model) in a clinically referred sample of 72 young people aged 8-14 years. Regression analyses revealed associations of conviction and grandiosity with reasoning; of frequency, and hallucinations and paranoia, with negative life events; and of distress/adverse life impact, and paranoia and hallucinations, with emotional problems. We conclude that psychological targets for intervention differ according to particular characteristics of childhood UEs in much the same way as for psychotic symptoms in adults. The development of targeted interventions is therefore indicated, and tailoring therapy according to presentation should further improve clinical outcomes for these young people.

  17. Examining item content and structure in health status and health outcomes instruments: toward the development of a grammar for better understanding of the concepts being measured.

    Science.gov (United States)

    Erickson, Pennifer; Willke, Richard J

    2013-06-01

    Health outcomes instruments assess diverse health concepts. Although item-level concepts are considered fundamental elements, the field lacks structures for evaluating and organizing them for decision making. This article proposes a grammar using item stems, response options, and recall periods to systematically identify item-level concepts. The grammar uses "core concept," "evaluative component," and "recall period" as intuitive terms for communicating with stakeholders. Better characterization of concepts is necessary for classifying instrument content and linking it to treatment benefit. Items in 2 generic and 21 disease-specific instruments were evaluated to develop and illustrate the use of the grammar. Concepts were assigned International Classification of Functioning, Disability and Health codes for exploring the value that the grammar and a classification system add to the understanding of content across instruments. The 23 instruments include many core concepts; emotional function is the only concept assessed in all instruments. Concepts in disease-specific instruments show obvious patterns; for example, arthritis instruments focus on physical function. The majority of instruments used the same response options across all items, with five-point scales being the most common. Most instruments used one recall period for all items. Shorter recall periods were used for conditions associated with "flares," such as chronic obstructive pulmonary disease and "skin disease." Every diagnosis, however, showed variation across instruments in the recall period used. This analysis indicates the proposed grammar's potential for discerning the conceptual content within and between health outcomes instruments and illustrates its value for improving communication between stakeholders and for making decisions related to treatment benefit. Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  18. The Development, Field Testing and Evaluation of Three Hierarchies of Behaviorally Stated Objectives for the Chemistry Content of a Course of Instruction in Physical Science for Pre-Service Nursing Students.

    Science.gov (United States)

    Love, Robert Alden

    The purpose of this research was to develop hierarchies of behavioral objectives for the chemistry content of a one-semester course in physical science for preservice associate degree nursing students. Each of three content objectives was expressed by a series of behaviorally stated objectives which included a terminal objective for a unit of…

  19. Development of a chromatographic method with multi-criteria decision making design for simultaneous determination of nifedipine and atenolol in content uniformity testing.

    Science.gov (United States)

    Ahmed, Sameh; Alqurshi, Abdulmalik; Mohamed, Abdel-Maaboud Ismail

    2018-07-01

    A new robust and reliable high-performance liquid chromatography (HPLC) method with multi-criteria decision making (MCDM) approach was developed to allow simultaneous quantification of atenolol (ATN) and nifedipine (NFD) in content uniformity testing. Felodipine (FLD) was used as an internal standard (I.S.) in this study. A novel marriage between a new interactive response optimizer and a HPLC method was suggested for multiple response optimizations of target responses. An interactive response optimizer was used as a decision and prediction tool for the optimal settings of target responses, according to specified criteria, based on Derringer's desirability. Four independent variables were considered in this study: Acetonitrile%, buffer pH and concentration along with column temperature. Eight responses were optimized: retention times of ATN, NFD, and FLD, resolutions between ATN/NFD and NFD/FLD, and plate numbers for ATN, NFD, and FLD. Multiple regression analysis was applied in order to scan the influences of the most significant variables for the regression models. The experimental design was set to give minimum retention times, maximum resolution and plate numbers. The interactive response optimizer allowed prediction of optimum conditions according to these criteria with a good composite desirability value of 0.98156. The developed method was validated according to the International Conference on Harmonization (ICH) guidelines with the aid of the experimental design. The developed MCDM-HPLC method showed superior robustness and resolution in short analysis time allowing successful simultaneous content uniformity testing of ATN and NFD in marketed capsules. The current work presents an interactive response optimizer as an efficient platform to optimize, predict responses, and validate HPLC methodology with tolerable design space for assay in quality control laboratories. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease.

    Science.gov (United States)

    Bakshi, Nitya; Stinson, Jennifer N; Ross, Diana; Lukombo, Ines; Mittal, Nonita; Joshi, Saumya V; Belfer, Inna; Krishnamurti, Lakshmanan

    2015-06-01

    Vaso-occlusive pain, the hallmark of sickle cell disease (SCD), is a major contributor to morbidity, poor health-related quality of life, and health care utilization associated with this disease. There is wide variation in the burden, frequency, and severity of pain experienced by patients with SCD. As compared with health care utilization for pain, a daily pain diary captures the breadth of the pain experience and is a superior measure of pain burden and its impact on patients. Electronic pain diaries based on real-time data capture methods overcome methodological barriers and limitations of paper pain diaries, but their psychometric properties have not been formally established in patients with SCD. To develop and establish the content validity of a web-based multidimensional pain diary for adolescents and young adults with SCD and conduct an end-user review to refine the prototype. Following identification of items, a conceptual model was developed. Interviews with adolescents and young adults with SCD were conducted. Subsequently, end-user review with use of the electronic pain diary prototype was conducted. Two iterative cycles of in-depth cognitive interviews in adolescents and young adults with SCD informed the design and guided the addition, removal, and modification of items in the multidimensional pain diary. Potential end-users provided positive feedback on the design and prototype of the electronic diary. A multidimensional web-based electronic pain diary for adolescents and young adults with SCD has been developed and content validity and initial end-user reviews have been completed.

  1. Content validity and its estimation

    Directory of Open Access Journals (Sweden)

    Yaghmale F

    2003-04-01

    Full Text Available Background: Measuring content validity of instruments are important. This type of validity can help to ensure construct validity and give confidence to the readers and researchers about instruments. content validity refers to the degree that the instrument covers the content that it is supposed to measure. For content validity two judgments are necessary: the measurable extent of each item for defining the traits and the set of items that represents all aspects of the traits. Purpose: To develop a content valid scale for assessing experience with computer usage. Methods: First a review of 2 volumes of International Journal of Nursing Studies, was conducted with onlyI article out of 13 which documented content validity did so by a 4-point content validity index (CV! and the judgment of 3 experts. Then a scale with 38 items was developed. The experts were asked to rate each item based on relevance, clarity, simplicity and ambiguity on the four-point scale. Content Validity Index (CVI for each item was determined. Result: Of 38 items, those with CVIover 0.75 remained and the rest were discarded reSulting to 25-item scale. Conclusion: Although documenting content validity of an instrument may seem expensive in terms of time and human resources, its importance warrants greater attention when a valid assessment instrument is to be developed. Keywords: Content Validity, Measuring Content Validity

  2. A case study on use of modified delphi technique for developing consensus on designing contents of a module for imparting sex education to adolescents in schools, in India

    Directory of Open Access Journals (Sweden)

    Deepak B. Saxena

    2012-06-01

    Full Text Available In the year 2007, eleven (11 of India’s 29 states suspended the federal initiative, ‘Adolescence Education Program’, under the name of School AIDS awareness education program (SAEP designed for 15- to 17-year-olds in all staterun schools and devised by the Ministry of Human Resource Development (HRD and National AIDS Control Organization (NACO on grounds that the flip charts used for training teachers contained explicit images of male and female reproductive systems, conception, and contraception. The aim of the present study is to understand usefulness of Delphi technique as a tool to develop contents and make consensus over a suitable module that can be utilized for imparting Sex Education to the Adolescents in school. The study present below used Delphi technique in transaction of the module recommended by National Council of Education Research and Training (NCERT for imparting Sex education under SAEP. Although the technique was successful in building consensus amongst different stake holders, within the limitations of Delphi like potential drop outs, loss to follow up and lack of clear verbal labels. It is concluded from the results of present study that Delphi technique, when rigorously administered, analyzed and reported, is a valuable method to help policy planners in developing the process for a suitable module that can be utilized for imparting sex education to adolescents in school.

  3. A case study on use of modified delphi technique for developing consensus on designing contents of a module for imparting sex education to adolescents in schools, in India

    Directory of Open Access Journals (Sweden)

    Deepak B. Saxena

    2012-01-01

    Full Text Available In the year 2007, eleven (11 of India’s 29 states suspended the federal initiative, ‘Adolescence Education Program’, under the name of School AIDS awareness education program (SAEP designed for 15- to 17-year-olds in all state- run schools and devised by the Ministry of Human Resource Development (HRD and National AIDS Control Organization (NACO on grounds that the flip charts used for training teachers contained explicit images of male and female reproductive systems, conception, and contraception. The aim of the present study is to understand usefulness of Delphi technique as a tool to develop contents and make consensus over a suitable module that can be utilized for imparting Sex Education to the Adolescents in school. The study present below used Delphi technique in transaction of the module recommended by National Council of Education Research and Training (NCERT for imparting Sex education under SAEP. Although the technique was successful in building consensus amongst different stake holders, within the limitations of Delphi like potential drop outs, loss to follow up and lack of clear verbal labels. It is concluded from the results of present study that Delphi technique, when rigorously administered, analyzed and reported, is a valuable method to help policy planners in developing the process for a suitable module that can be utilized for imparting sex education to adolescents in school

  4. Development and Evaluation of the Tigriopus Course-Based Undergraduate Research Experience: Impacts on Students’ Content Knowledge, Attitudes, and Motivation in a Majors Introductory Biology Course

    Science.gov (United States)

    Olimpo, Jeffrey T.; Fisher, Ginger R.; DeChenne-Peters, Sue Ellen

    2016-01-01

    Within the past decade, course-based undergraduate research experiences (CUREs) have emerged as a viable mechanism to enhance novices’ development of scientific reasoning and process skills in the science, technology, engineering, and mathematics disciplines. Recent evidence within the bioeducation literature suggests that student engagement in such experiences not only increases their appreciation for and interest in scientific research but also enhances their ability to “think like a scientist.” Despite these critical outcomes, few studies have objectively explored CURE versus non-CURE students’ development of content knowledge, attitudes, and motivation in the discipline, particularly among nonvolunteer samples. To address these concerns, we adopted a mixed-methods approach to evaluate the aforementioned outcomes following implementation of a novel CURE in an introductory cell/molecular biology course. Results indicate that CURE participants exhibited more expert-like outcomes on these constructs relative to their non-CURE counterparts, including in those areas related to self-efficacy, self-determination, and problem-solving strategies. Furthermore, analysis of end-of-term survey data suggests that select features of the CURE, such as increased student autonomy and collaboration, mediate student learning and enjoyment. Collectively, this research provides novel insights into the benefits achieved as a result of CURE participation and can be used to guide future development and evaluation of authentic research opportunities. PMID:27909022

  5. Exposure to coal combustion residues during metamorphosis elevates corticosterone content and adversely affects oral morphology, growth, and development in Rana sphenocephala

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, J.D.; Peterson, V.A.; Mendonca, M.T. [Auburn University, Auburn, AL (USA). Dept. of Biological Science

    2009-01-15

    Coal combustion residues (CCRs) are documented to negatively impact oral morphology, growth, and development in larval amphibians. It is currently unclear what physiological mechanisms may mediate these effects. Corticosterone, a glucocorticoid hormone, is a likely mediator because when administered exogenously it, like CCRs, also negatively influences oral morphology, growth, and development in larval amphibians. In an attempt to identify if corticosterone mediates these effects, we raised larval Southern Leopard Frogs, Rana sphenocephala, on either sand or CCR substrate and documented effects of sediment type on whole body corticosterone, oral morphology, and time to and mass at key metamorphic stages. Coal combustion residue treated tadpoles contained significantly more corticosterone than controls throughout metamorphosis. However, significantly more oral abnormalities occurred early in metamorphosis when differences in corticosterone levels between treatments were minimal. Overall, CCR-treated tadpoles took significantly more time to transition between key stages and gained less mass between stages than controls, but these differences between treatments decreased during later stages when corticosterone differences between treatments were greatest. Our results suggest endogenous increase in corticosterone content and its influence on oral morphology, growth and development is more complex than previously thought.

  6. Development of capacitive sensor for measuring soil water content Desenvolvimento de sensor capacitivo para a medição do teor de água do solo

    Directory of Open Access Journals (Sweden)

    Alan K. Rêgo Segundo

    2011-04-01

    Full Text Available The irrigation management based on the monitoring of the soil water content allows for the minimization of the amount of water applied, making its use more efficient. Taking into account these aspects, in this work, a sensor for measuring the soil water content was developed to allow real time automation of irrigation systems. This way, problems affecting crop yielding such as irregularities in the time to turn on or turn off the pump, and excess or deficit of water can be solved. To develop the sensors were used stainless steel rods, resin, and insulating varnish. The sensors measuring circuit was based on a microcontroller, which gives its output signal in the digital format. The sensors were calibrated using soil of the type “Quartzarenic Neosoil”. A third order polynomial model was fitted to the experimental data between the values of water content corresponding to the field capacity and the wilting point to correlate the soil water content obtained by the oven standard method with those measured by the electronic circuit, with a coefficient of determination of 93.17%, and an accuracy in the measures of ±0.010 kg kg-1. Based on the results, it was concluded that the sensor and its implemented measuring circuit can be used in the automation process of irrigation systems.O manejo da irrigação, com base no monitoramento do teor de água do solo, permite racionalizar a quantidade de água aplicada, tornando o seu uso mais eficiente. Levando-se em conta esses aspectos, foi desenvolvido um sensor capacitivo de teor de água do solo e seu circuito de medição para que sistemas de irrigação possam ser automatizados. Desta forma, problemas que afetam a produtividade, tais como irregularidades no acionamento e aplicação de água de maneira excessiva ou deficiente, podem ser contornados. No desenvolvimento dos sensores, foram utilizadas hastes de aço inoxidável, resina e verniz isolante. O circuito de medição foi baseado em um

  7. Development and molecular characterization of genic molecular markers for grain protein and calcium content in finger millet (Eleusine coracana (L.) Gaertn.).

    Science.gov (United States)

    Nirgude, M; Babu, B Kalyana; Shambhavi, Y; Singh, U M; Upadhyaya, H D; Kumar, Anil

    2014-03-01

    Finger millet (Eleusine coracana (L.) Gaertn), holds immense agricultural and economic importance for its high nutraceuticals quality. Finger millets seeds are rich source of calcium and its proteins are good source of essential amino acids. In the present study, we developed 36 EST-SSR primers for the opaque2 modifiers and 20 anchored-SSR primers for calcium transporters and calmodulin for analysis of the genetic diversity of 103 finger millet genotypes for grain protein and calcium contents. Out of the 36 opaque2 modifiers primers, 15 were found polymorphic and were used for the diversity analysis. The highest PIC value was observed with the primer FMO2E33 (0.26), while the lowest was observed FMO2E27 (0.023) with an average value of 0.17. The gene diversity was highest for the primer FMO2E33 (0.33), however it was lowest for FMO2E27 (0.024) at average value of 0.29. The percentage polymorphism shown by opaque2 modifiers primers was 68.23%. The diversity analysis by calcium transporters and calmodulin based anchored SSR loci revealed that the highest PIC was observed with the primer FMCA8 (0.30) and the lowest was observed for FMCA5 (0.023) with an average value of 0.18. The highest gene diversity was observed for primer FMCA8 (0.37), while lowest for FMCA5 (0.024) at an average of 0.21. The opaque2 modifiers specific EST-SSRs could able to differentiate the finger millet genotypes into high, medium and low protein containing genotypes. However, calcium dependent candidate gene based EST-SSRs could broadly differentiate the genotypes based on the calcium content with a few exceptions. A significant negative correlation between calcium and protein content was observed. The present study resulted in identification of highly polymorphic primers (FMO2E30, FMO2E33, FMO2-18 and FMO2-14) based on the parameters such as percentage of polymorphism, PIC values, gene diversity and number of alleles.

  8. Development of Selectable Marker-Free Transgenic Rice Plants with Enhanced Seed Tocopherol Content through FLP/FRT-Mediated Spontaneous Auto-Excision.

    Directory of Open Access Journals (Sweden)

    Hee-Jong Woo

    Full Text Available Development of marker-free transgenic plants is a technical alternative for avoiding concerns about the safety of selectable marker genes used in genetically modified (GM crops. Here, we describe the construction of a spontaneous self-excision binary vector using an oxidative stress-inducible modified FLP/FRT system and its successful application to produce marker-free transgenic rice plants with enhanced seed tocopherol content. To generate selectable marker-free transgenic rice plants, we constructed a binary vector using the hpt selectable marker gene and the rice codon-optimized FLP (mFLP gene under the control of an oxidative stress-inducible promoter between two FRT sites, along with multiple cloning sites for convenient cloning of genes of interest. Using this pCMF binary vector with the NtTC gene, marker-free T1 transgenic rice plants expressing NtTC were produced by Agrobacterium-mediated stable transformation using hygromycin as a selective agent, followed by segregation of selectable marker genes. Furthermore, α-, γ-, and total tocopherol levels were significantly increased in seeds of the marker-free transgenic TC line compared with those of wild-type plants. Thus, this spontaneous auto-excision system, incorporating an oxidative stress-inducible mFLP/FRT system to eliminate the selectable marker gene, can be easily adopted and used to efficiently generate marker-free transgenic rice plants. Moreover, nutritional enhancement of rice seeds through elevation of tocopherol content coupled with this marker-free strategy may improve human health and public acceptance of GM rice.

  9. Development of Selectable Marker-Free Transgenic Rice Plants with Enhanced Seed Tocopherol Content through FLP/FRT-Mediated Spontaneous Auto-Excision.

    Science.gov (United States)

    Woo, Hee-Jong; Qin, Yang; Park, Soo-Yun; Park, Soon Ki; Cho, Yong-Gu; Shin, Kong-Sik; Lim, Myung-Ho; Cho, Hyun-Suk

    2015-01-01

    Development of marker-free transgenic plants is a technical alternative for avoiding concerns about the safety of selectable marker genes used in genetically modified (GM) crops. Here, we describe the construction of a spontaneous self-excision binary vector using an oxidative stress-inducible modified FLP/FRT system and its successful application to produce marker-free transgenic rice plants with enhanced seed tocopherol content. To generate selectable marker-free transgenic rice plants, we constructed a binary vector using the hpt selectable marker gene and the rice codon-optimized FLP (mFLP) gene under the control of an oxidative stress-inducible promoter between two FRT sites, along with multiple cloning sites for convenient cloning of genes of interest. Using this pCMF binary vector with the NtTC gene, marker-free T1 transgenic rice plants expressing NtTC were produced by Agrobacterium-mediated stable transformation using hygromycin as a selective agent, followed by segregation of selectable marker genes. Furthermore, α-, γ-, and total tocopherol levels were significantly increased in seeds of the marker-free transgenic TC line compared with those of wild-type plants. Thus, this spontaneous auto-excision system, incorporating an oxidative stress-inducible mFLP/FRT system to eliminate the selectable marker gene, can be easily adopted and used to efficiently generate marker-free transgenic rice plants. Moreover, nutritional enhancement of rice seeds through elevation of tocopherol content coupled with this marker-free strategy may improve human health and public acceptance of GM rice.

  10. 數位學習科技化教學教材發展趨勢The Educational Technology and eLearning Content Developing Trends

    Directory of Open Access Journals (Sweden)

    李鎮宇Chen-Yu Lee

    2011-03-01

    Full Text Available 數位學習隨著網路、科技的發達,不停的進步與演化,今日的學習概念、學習方式已與上一個世紀大異其趣。從第一代單機電腦的數位教材,轉化到如今正蓬勃發展的行動學習,其教學重心也從老師身上移轉至以學生為中心之教學方法,而隨著網路web 2.0概念的盛行,目前已進入非正式、行動學習的世代。本文透過檢視不同類別之科技化教學與數位學習教材,分析國內外目前與未來的發展趨勢,包含模擬式教材、擴增實境技術、開放式課程、互動導學式課程等,透過研究針對我國教學市場需求與新興科技產品發展,提出結合行動科技之無縫式(seamless)科技化教學概念,綜合以上結論,數位學習教材除了現有的數位內容將持續發展之外,無縫式行動學習內容與3D體驗式學習將是未來數位學習教材發展的主要趨勢。The development of eLearning has been evolved dramatically along with Internet and advanced Technology. Learning style and methods today are very different from the last century. Stand-alone computer training from the first generation of eLearning has now being transformed into booming mobile learning. The focus of teaching has shifted from teachers to student-centered. As the popularity of Web 2.0 grows, informal and mobile learning become the primary learning source. This paper exams different types of eLearning content including simulation, augmented reality, open courseware, interactive instructor led materials and etc. Through the study of Taiwan’s teaching and learning market demands and innovated technology development, this paper addresses some innovated seamless learning strategy integrated mobile technologies. eLearning content will continue its development in the existence area. However, seamless mobile learning and 3D-experienced learning will be the primary trends in the future eLearning content

  11. Development of high, medium and low oil content hydro cyclones; Desenvolvimento de hidrociclones para altos, medios e baixos teores de oleo

    Energy Technology Data Exchange (ETDEWEB)

    Moraes, Carlos Alberto Capela; Marins, Luiz Philipe Martinez; Melo, Darley Carrijo de; Silva, Fabricio Soares da [Centro de Pesquisas da Petrobras (CENPES). Gerencia de Tecnologia de Processamento e Avaliacao de Petroleo (Brazil)], e-mails: capela@petrobras.com.br, philipe@petrobras.com.br, darley@petrobras.com.br, fabriciosoares@petrobras.com.br; Oliveira Junior, Joao Americo Aguirre [Engineering Simulation and Scientific Software (ESSS), Florianopolis, SC (Brazil)], e-mail: aguirre@esss.com.br; Souza, Marcos Aurelio de; Barca, Luiz Fernando [Universidade Federal de Itajuba. Instituto de Engenharia Mecanica, MG (Brazil)], e-mails: maurelio@unifei.edu.br, barca@unifei.edu.br; Souza, Adriana Margarida Rodrigues Ferreira de [Fundacao Gorceix (Brazil)], e-mail: adrianamargarida.gorceix@petrobras.com.br; Almeida, Cristina Santos de [Universidade Federal do Rio de Janeiro. Fundacao de Coordenacao de Projetos, Pesquisa e Estudos Tecnologicos (COPPETEC/UFRJ). Escola de Quimica, RJ (Brazil)], e-mail: cristinaalmeida.coppetec@petrobras.com.br

    2008-12-15

    This paper is intended to describe the steps and present the results of a Research and Development (P and D) project aimed at developing and qualifying hydro cyclones for oil and water primary separation by PETROBRAS. The hydro cyclones families for high, medium and low oil content, respectively named as ATO, MTO and BTO were developed in this project and are currently in the patent filing phase. The members of each one of them were initially conceived and analyzed by means of numeric simulations (CFD). The set-ups for these simulations were based on experimental investigation supplemental papers of the fluid-dynamics in hydro cyclones, with the use of Laser Doppler Anemometry (LDA and PIV) in acrylic models. After the selection of the geometries for optimum performance at the CFD, actual size steel prototypes were designed and built for each one of the aforementioned hydro cyclones families. It was also designed and built a two-skid mounted system and one control rack which comprise a Mobile Lab for Hydro cyclone Tests (LMTH, being the acronym in Portuguese) with which field tests were carried out (Buracica Field, Bahia) in the prototypes. As the last phase of the Research and Development (R and D) project, it was prepared a computer routine which allows the performance of a project of a compact separation system for any specific application, using the hydro cyclones of the families aforementioned in series in the streams rich in water. This routine enables, from the features of the fluids in the application in particular, to select the most appropriate hydro cyclone to be used, obtain their corresponding operating conditions and also to obtain an estimate of the minimum performance range expected in the application under analysis. (author)

  12. Perspectives of Iranian male nursing students regarding the role of nursing education in developing a professional identity: a content analysis study.

    Science.gov (United States)

    Vaismoradi, Mojtaba; Salsali, Mahvash; Ahmadi, Fazlollah

    2011-12-01

    The purpose of the present study was to explore the perspectives of Iranian male nursing students regarding the role of nursing education in developing a professional identity. A qualitative design, based on the content analysis approach, was used to collect the data and analyze the perspectives of 14 Iranian male nursing students who were chosen by using a purposive sampling strategy. After the selection of the participants, semistructured interviews were held in order to collect the data. During the data analysis, three main themes emerged: "reality-expectation incompatibility", "being supported by the educational system", and "nursing image rectification". The second theme consisted of two categories: "feeling trusted" and "being defended". This study will be useful to nurse educators and administrators in relation to what constitutes nursing students' professional identity within the Iranian culture and context and how nursing education can play an effective role in developing their professional identity in order to devise strategies to attract male students to the nursing profession and promote their retention after graduation. © 2010 The Authors. Japan Journal of Nursing Science © 2010 Japan Academy of Nursing Science.

  13. Early language development in children with profound hearing loss fitted with a device at a young age: part II--content of the first lexicon.

    Science.gov (United States)

    Nott, Pauline; Cowan, Robert; Brown, P Margaret; Wigglesworth, Gillian

    2009-10-01

    used proportionately more nouns, fewer predicates, more common nouns, and fewer onomatopoeic words compared with the HL group. Further, more participants in the hearing group used grammatical word types other than adverbs (including pronouns) compared with the HL group. Overall, lexical content of the HL group was similar to that of the hearing group for both the 50- and 100-word lexicons, although some differences in proportional use were noted across word categories and types. It is suggested that differences in the quantity and diversity of language experienced by children with normal hearing compared with those with HL, together with differences in the input they receive, might in part explain these differences. The effect of quality of speech input and therapy method on the emerging lexicon and subsequent language development will be particularly important in informing appropriate intervention strategies for children with HL.

  14. Development of a regulatory guide about the content and criteria for the elaboration of the radioactive waste management plans in Spanish nuclear facilities

    International Nuclear Information System (INIS)

    Lopez de la Higuera, Julia; Alvarez Alonso, M. Angeles; Simon Cirujano, Maria I.; Suarez Llorente, Beatriz

    2008-01-01

    Full text:The Spanish legislation requires the licensees to develop, among other documents, a Radioactive Waste Management Plan (RWMP) as an official report in the application for the operation and for the dismantling and decommissioning of a nuclear facility. These Plans should describe the types of waste, inventory, characterization, treatment, conditioning and storage of wastes. The Spanish regulatory body, Consejo de Seguridad Nuclear (CSN), promoted a working group to analyze the content and scope of the RWMP, bringing together the electric power industry association (UNESA), the waste management organisation (ENRESA) and the nuclear fuel industry (ENUSA). The objective of the RWMP is to establish the criteria and instructions to ensure a safe and optimized management, taking into account the normative and technological developments. The Plan is based on support Studies that contain the basic information for the analysis of the waste management options and deals with: (1) Actual generation and management options in the facility; (2) Classification of the facility in waste generation zones; (3) Experience analysis and identification of potential management improvements; (4) Selection, justification and introduction of new management modes. The RWMP will develop the following issues: a) Waste generation and management (for each waste type, information in terms of the origin, physico-chemical and radiological properties, volume of production and implemented management routes); b) Classification of the facility in waste zones. The facility will differentiate those areas where contaminated or activated wastes can be produced (Radioactive Waste Zone - RWZ) or not (Conventional Waste Zone - CWZ). To avoid mixing and allow this separation, two lines of defense will be established. The first one is the classification and setting marks in the Zones and the second one the controls on the non-radioactive wastes at the exit of the facility: a) Selection of foreseen lines

  15. Development and Evaluation of the Tigriopus Course-Based Undergraduate Research Experience: Impacts on Students' Content Knowledge, Attitudes, and Motivation in a Majors Introductory Biology Course.

    Science.gov (United States)

    Olimpo, Jeffrey T; Fisher, Ginger R; DeChenne-Peters, Sue Ellen

    2016-01-01

    Within the past decade, course-based undergraduate research experiences (CUREs) have emerged as a viable mechanism to enhance novices' development of scientific reasoning and process skills in the science, technology, engineering, and mathematics disciplines. Recent evidence within the bioeducation literature suggests that student engagement in such experiences not only increases their appreciation for and interest in scientific research but also enhances their ability to "think like a scientist." Despite these critical outcomes, few studies have objectively explored CURE versus non-CURE students' development of content knowledge, attitudes, and motivation in the discipline, particularly among nonvolunteer samples. To address these concerns, we adopted a mixed-methods approach to evaluate the aforementioned outcomes following implementation of a novel CURE in an introductory cell/molecular biology course. Results indicate that CURE participants exhibited more expert-like outcomes on these constructs relative to their non-CURE counterparts, including in those areas related to self-efficacy, self-determination, and problem-solving strategies. Furthermore, analysis of end-of-term survey data suggests that select features of the CURE, such as increased student autonomy and collaboration, mediate student learning and enjoyment. Collectively, this research provides novel insights into the benefits achieved as a result of CURE participation and can be used to guide future development and evaluation of authentic research opportunities. © 2016 J. T. Olimpo et al. CBE—Life Sciences Education © 2016 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  16. Developing Content Knowledge in Students through Explicit Teaching of the Nature of Science: Influences of Goal Setting and Self-Monitoring

    Science.gov (United States)

    Peters, Erin E.

    2012-01-01

    Knowledge about the nature of science has been advocated as an important component of science because it provides a framework on which the students can incorporate content knowledge. However, little empirical evidence has been provided that links nature of science knowledge with content knowledge. The purpose of this mixed method study was to…

  17. Development and validation of a new spectrofluorimetric method for the determination of some beta-blockers through fluorescence quenching of eosin Y. Application to content uniformity test

    Directory of Open Access Journals (Sweden)

    Derayea Sayed M

    2016-01-01

    Full Text Available A simple, rapid, sensitive and economic spectrofluorimetric method has been developed and validated for determination of some β-adrenergic blocking agents namely; betaxolol hydrochloride (BTX, carvedilol (CAR, labetalol hydrochloride (LBT, nebivolol hydrochloride (NEB and propranolol hydrochloride (PRO. The method is based on the quenching effect of the cited drugs on the fluorescence intensity of eosin Y at pH 3.4 (acetate buffer. The fluorescence quenching is due to the formation of an ion-pair complex and was measured without extraction at 545 nm (λex. 301.5 nm. The factors affecting the formation of the ion-pair complex were carefully studied and optimized. Under the optimal conditions, the linear ranges for the relationship between the fluorescence quenching value and the concentration of the investigated drugs were 100-2500, 150-2500 and 50-2250 ng mL-1 for (BTX, CAR, (LBT, NEB and (PRO respectively. The method was validated according to ICH guidelines and was applied for determination of the cited drugs in pharmaceutical dosage forms with excellent recoveries. In addition, content uniformity testing of some commercial dosage forms was checked by the proposed method.

  18. Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells

    Science.gov (United States)

    Nguyen, Minh M.; Dar, Javid A.; Ai, Junkui; Wang, Yujuan; Masoodi, Khalid Z.; Shun, Tongying; Shinde, Sunita; Camarco, Daniel P.; Hua, Yun; Huryn, Donna M.; Wilson, Gabriela Mustata; Lazo, John S.; Nelson, Joel B.; Wipf, Peter

    2016-01-01

    Abstract Patients with castration-resistant prostate cancer (CRPC) can be treated with abiraterone, a potent inhibitor of androgen synthesis, or enzalutamide, a second-generation androgen receptor (AR) antagonist, both targeting AR signaling. However, most patients relapse after several months of therapy and a majority of patients with relapsed CRPC tumors express the AR target gene prostate-specific antigen (PSA), suggesting that AR signaling is reactivated and can be targeted again to inhibit the relapsed tumors. Novel small molecules capable of inhibiting AR function may lead to urgently needed therapies for patients resistant to abiraterone, enzalutamide, and/or other previously approved antiandrogen therapies. Here, we describe a high-throughput high-content screening (HCS) campaign to identify small-molecule inhibitors of AR nuclear localization in the C4-2 CRPC cell line stably transfected with GFP-AR-GFP (2GFP-AR). The implementation of this HCS assay to screen a National Institutes of Health library of 219,055 compounds led to the discovery of 3 small molecules capable of inhibiting AR nuclear localization and function in C4-2 cells, demonstrating the feasibility of using this cell-based phenotypic assay to identify small molecules targeting the subcellular localization of AR. Furthermore, the three hit compounds provide opportunities to develop novel AR drugs with potential for therapeutic intervention in CRPC patients who have relapsed after treatment with antiandrogens, such as abiraterone and/or enzalutamide. PMID:27187604

  19. Development and validation of a sensitive LC-MS-MS method for the simultaneous determination of multicomponent contents in artificial Calculus Bovis.

    Science.gov (United States)

    Peng, Can; Tian, Jixin; Lv, Mengying; Huang, Yin; Tian, Yuan; Zhang, Zunjian

    2014-02-01

    Artificial Calculus Bovis is a major substitute in clinical treatment for Niuhuang, a widely used, efficacious but rare traditional Chinese medicine. However, its chemical structures and the physicochemical properties of its components are complicated, which causes difficulty in establishing a set of effective and comprehensive methods for its identification and quality control. In this study, a simple, sensitive and reliable liquid chromatography-tandem mass spectrometry method was successfully developed and validated for the simultaneous determination of bilirubin, taurine and major bile acids (including six unconjugated bile acids, two glycine-conjugated bile acids and three taurine-conjugated bile acids) in artificial Calculus Bovis using a Zorbax SB-C18 column with a gradient elution of methanol and 10 mmol/L ammonium acetate in aqueous solution (adjusted to pH 3.0 with formic acid). The mass spectra were obtained in the negative ion mode using dehydrocholic acid as the internal standard. The content of each analyte in artificial Calculus Bovis was determined by monitoring specific ion pairs in the selected reaction monitoring mode. All analytes demonstrated perfect linearity (r(2) > 0.994) in a wide dynamic range, and 10 batches of samples from different sources were further analyzed. This study provided a comprehensive method for the quality control of artificial Calculus Bovis.

  20. Development of a peptide nucleic acid polymerase chain reaction clamping assay for semiquantitative evaluation of genetically modified organism content in food.

    Science.gov (United States)

    Peano, C; Lesignoli, F; Gulli, M; Corradini, R; Samson, M C; Marchelli, R; Marmiroli, N

    2005-09-15

    In the present study a peptide nucleic acid (PNA)-mediated polymerase chain reaction (PCR) clamping method was developed and applied to the detection of genetically modified organisms (GMO), to test PCR products for band identity and to obtain a semiquantitative evaluation of GMO content. The minimal concentration of PNA necessary to block the PCR was determined by comparing PCRs containing a constant amount of DNA in the presence of increasing concentration of target-specific PNA. The lowest PNA concentration at which specific inhibition took place, by the inhibition of primer extension and/or steric hindrance, was the most efficient condition. Optimization of PCR clamping by PNA was observed by testing five different PNAs with a minimum of 13 bp to a maximum of 15 bp, designed on the target sequence of Roundup Ready soybean. The results obtained on the DNA extracted from Roundup Ready soybean standard flour were verified also on DNA extracted from standard flours of maize GA21, Bt176, Bt11, and MON810. A correlation between the PNA concentration necessary for inducing PCR clamping and the percentage of the GMO target sequence in the sample was found.

  1. Development of a self-report questionnaire designed for population-based surveillance of gingivitis in adolescents: assessment of content validity and reliability

    Science.gov (United States)

    QUIROZ, Viviana; REINERO, Daniela; HERNÁNDEZ, Patricia; CONTRERAS, Johanna; VERNAL, Rolando; CARVAJAL, Paola

    2017-01-01

    Abstract The major infectious diseases in Chile encompass the periodontal diseases, with a combined prevalence that rises up to 90% of the population. Thus, the population-based surveillance of periodontal diseases plays a central role for assessing their prevalence and for planning, implementing, and evaluating preventive and control programs. Self-report questionnaires have been proposed for the surveillance of periodontal diseases in adult populations world-wide. Objective This study aimed to develop and assess the content validity and reliability of a cognitively adapted self-report questionnaire designed for surveillance of gingivitis in adolescents. Material and Methods Ten predetermined self-report questions evaluating early signs and symptoms of gingivitis were preliminary assessed by a panel of clinical experts. Eight questions were selected and cognitively tested in 20 adolescents aged 12 to 18 years from Santiago de Chile. The questionnaire was then conducted and answered by 178 Chilean adolescents. Internal consistency was measured using the Cronbach’s alpha and temporal stability was calculated using the Kappa-index. Results A reliable final self-report questionnaire consisting of 5 questions was obtained, with a total Cronbach’s alpha of 0.73 and a Kappa-index ranging from 0.41 to 0.77 between the different questions. Conclusions The proposed questionnaire is reliable, with an acceptable internal consistency and a temporal stability from moderate to substantial, and it is promising for estimating the prevalence of gingivitis in adolescents. PMID:28877279

  2. Development of a self-report questionnaire designed for population-based surveillance of gingivitis in adolescents: assessment of content validity and reliability.

    Science.gov (United States)

    Quiroz, Viviana; Reinero, Daniela; Hernández, Patricia; Contreras, Johanna; Vernal, Rolando; Carvajal, Paola

    2017-01-01

    This study aimed to develop and assess the content validity and reliability of a cognitively adapted self-report questionnaire designed for surveillance of gingivitis in adolescents. Ten predetermined self-report questions evaluating early signs and symptoms of gingivitis were preliminary assessed by a panel of clinical experts. Eight questions were selected and cognitively tested in 20 adolescents aged 12 to 18 years from Santiago de Chile. The questionnaire was then conducted and answered by 178 Chilean adolescents. Internal consistency was measured using the Cronbach's alpha and temporal stability was calculated using the Kappa-index. A reliable final self-report questionnaire consisting of 5 questions was obtained, with a total Cronbach's alpha of 0.73 and a Kappa-index ranging from 0.41 to 0.77 between the different questions. The proposed questionnaire is reliable, with an acceptable internal consistency and a temporal stability from moderate to substantial, and it is promising for estimating the prevalence of gingivitis in adolescents.

  3. Development of a self-report questionnaire designed for population-based surveillance of gingivitis in adolescents: assessment of content validity and reliability

    Directory of Open Access Journals (Sweden)

    Viviana QUIROZ

    Full Text Available Abstract The major infectious diseases in Chile encompass the periodontal diseases, with a combined prevalence that rises up to 90% of the population. Thus, the population-based surveillance of periodontal diseases plays a central role for assessing their prevalence and for planning, implementing, and evaluating preventive and control programs. Self-report questionnaires have been proposed for the surveillance of periodontal diseases in adult populations world-wide. Objective This study aimed to develop and assess the content validity and reliability of a cognitively adapted self-report questionnaire designed for surveillance of gingivitis in adolescents. Material and Methods Ten predetermined self-report questions evaluating early signs and symptoms of gingivitis were preliminary assessed by a panel of clinical experts. Eight questions were selected and cognitively tested in 20 adolescents aged 12 to 18 years from Santiago de Chile. The questionnaire was then conducted and answered by 178 Chilean adolescents. Internal consistency was measured using the Cronbach’s alpha and temporal stability was calculated using the Kappa-index. Results A reliable final self-report questionnaire consisting of 5 questions was obtained, with a total Cronbach’s alpha of 0.73 and a Kappa-index ranging from 0.41 to 0.77 between the different questions. Conclusions The proposed questionnaire is reliable, with an acceptable internal consistency and a temporal stability from moderate to substantial, and it is promising for estimating the prevalence of gingivitis in adolescents.

  4. Obtaining Networked Scintillation and Total Electron Content Data Across Africa and Asia: Partnering with the IHY/UNBSSI Developing Nations Program

    Science.gov (United States)

    Groves, K. M.; Basu, S.; Erickson, T.; Sunanda, B.; David, B.

    2005-12-01

    Under the Scintillation Network Decision Aid (SCINDA) project, scientists at the Air Force Research Laboratory (AFRL) have developed a sensor network for the purpose of monitoring low-latitude ionospheric total electron content (TEC) and scintillations associated with equatorial Spread F. In addition to monitoring GPS scintillations, TEC and VHF scintillations, the sensor package measures ionospheric drifts when irregularities are present providing important data on vertical electric fields in the F-region .The network currently consists of twelve stations distributed around the globe and the data have been used to conduct numerous studies on the characteristics and climatology of equatorial scintillation, including the impacts of magnetic storms on the equatorial ionosphere. Notably absent from the existing network are observing sites in Africa where both satellite observations and limited historical data sets suggest significant scintillation activity, though the detailed behavior and longitudinal variations across the continent are largely unknown. The latter aspect, in particular, is of great interest because of substantial changes in the orientation of the geomagnetic field in extreme West Africa that transition to a more uniform field geometry spanning the rest of the continent. Understanding the effects of these changes on scintillation climatology will provide new insights into the processes that trigger equatorial Spread F and assist researchers in developing improved forecasts of such activity. AFRL aims to establish 5-8 monitoring sites across equatorial Africa in collaboration with host nations participating in the United Nations Basic Space Science Initiative during the IHY period. In addition to expanding scientific opportunities, it is hoped that these sites will lead to greater awareness of the significant space weather issues impacting Africa and result in enhanced international collaboration between both African and non-African scientists

  5. Analysis of Maths Learning Activities Developed By Pre-service Teachers in Terms of the Components of Content, Purpose, Application Methods

    Directory of Open Access Journals (Sweden)

    Çağla Toprak

    2014-04-01

    Full Text Available Today- when the influence of the alteration movement done in order to keep up with the age of the educational system is still continuing- the importance of teachers in students’ learning and achieving what is expected from the education system has been stated by the studies conducted (Hazır & Bıkmaz, 2006. Teachers own a critical role in the stage of both preparing teaching materials and using them (Stein & Smith, 1998b; Swan, 2007. When the existing curriculums –in particular, maths and geometry cirriculums- are analyzed, it can be observed that activities are the most significant teaching materials (Bozkurt, 2012. In fact, it is possible to characterize the existing curriculums as activity-based ones (Report of Workshop Examining Content of Primary School Curriculums According to Branches, 2010; Epö, 2005. Therefore, what sort of learning activities there are, what qualities they need to have, how to design and apply them are topics that must be elaborated (Uğurel et al., 2010.  At this point, our study to increase the skills of pre-service teachers during the process of developing activities was conducted with 27 pre-service teachers -19 girls 8 boys- studying in the 4th year in Mathematics Education Department at a state university in the Aegean Region. The activity designs the pre-service teachers developed considering the patterns given after a series of practice were analyzed in documents in terms of the aim of design and the form of practice. As a result of the studies, it is observed that pre-service teachers deal with the topics from the maths curriculum and these topics are of different grade levels. The result of the examination named as target component suggests that activities developed aim firstly at providing learning and this is followed by reinforcing the concepts already learned. It is stated that pre-service teachers prefer mostly small group (cooperative studies in the activities they develop.Key Words:

  6. Development and content validity testing of a patient-reported outcomes questionnaire for the assessment of hereditary angioedema in observational studies.

    Science.gov (United States)

    Bonner, Nicola; Abetz-Webb, Linda; Renault, Lydie; Caballero, Teresa; Longhurst, Hilary; Maurer, Marcus; Christiansen, Sandra; Zuraw, Bruce

    2015-07-01

    development of a content valid questionnaire that assesses concepts important to HAE patients globally. HAE patients across cultures consider the HAE PRO a relevant and appropriate assessment of HAE attacks and treatment.

  7. Webizing mobile augmented reality content

    Science.gov (United States)

    Ahn, Sangchul; Ko, Heedong; Yoo, Byounghyun

    2014-01-01

    This paper presents a content structure for building mobile augmented reality (AR) applications in HTML5 to achieve a clean separation of the mobile AR content and the application logic for scaling as on the Web. We propose that the content structure contains the physical world as well as virtual assets for mobile AR applications as document object model (DOM) elements and that their behaviour and user interactions are controlled through DOM events by representing objects and places with a uniform resource identifier. Our content structure enables mobile AR applications to be seamlessly developed as normal HTML documents under the current Web eco-system.

  8. LCS Content Document Application

    Science.gov (United States)

    Hochstadt, Jake

    2011-01-01

    My project at KSC during my spring 2011 internship was to develop a Ruby on Rails application to manage Content Documents..A Content Document is a collection of documents and information that describes what software is installed on a Launch Control System Computer. It's important for us to make sure the tools we use everyday are secure, up-to-date, and properly licensed. Previously, keeping track of the information was done by Excel and Word files between different personnel. The goal of the new application is to be able to manage and access the Content Documents through a single database backed web application. Our LCS team will benefit greatly with this app. Admin's will be able to login securely to keep track and update the software installed on each computer in a timely manner. We also included exportability such as attaching additional documents that can be downloaded from the web application. The finished application will ease the process of managing Content Documents while streamlining the procedure. Ruby on Rails is a very powerful programming language and I am grateful to have the opportunity to build this application.

  9. Content validity--establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO good research practices task force report: part 1--eliciting concepts for a new PRO instrument.

    Science.gov (United States)

    Patrick, Donald L; Burke, Laurie B; Gwaltney, Chad J; Leidy, Nancy Kline; Martin, Mona L; Molsen, Elizabeth; Ring, Lena

    2011-12-01

    The importance of content validity in developing patient reported outcomes (PRO) instruments is stressed by both the US Food and Drug Administration and the European Medicines Agency. Content validity is the extent to which an instrument measures the important aspects of concepts that developers or users purport it to assess. A PRO instrument measures the concepts most significant and relevant to a patient's condition and its treatment. For PRO instruments, items and domains as reflected in the scores of an instrument should be important to the target population and comprehensive with respect to patient concerns. Documentation of target population input in item generation, as well as evaluation of patient understanding through cognitive interviewing, can provide the evidence for content validity. Developing content for, and assessing respondent understanding of, newly developed PRO instruments for medical product evaluation will be discussed in this two-part ISPOR PRO Good Research Practices Task Force Report. Topics include the methods for generating items, documenting item development, coding of qualitative data from item generation, cognitive interviewing, and tracking item development through the various stages of research and preparing this tracking for submission to regulatory agencies. Part 1 covers elicitation of key concepts using qualitative focus groups and/or interviews to inform content and structure of a new PRO instrument. Part 2 covers the instrument development process, the assessment of patient understanding of the draft instrument using cognitive interviews and steps for instrument revision. The two parts are meant to be read together. They are intended to offer suggestions for good practices in planning, executing, and documenting qualitative studies that are used to support the content validity of PRO instruments to be used in medical product evaluation. Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR

  10. Developing Content Knowledge in Students Through Explicit Teaching of the Nature of Science: Influences of Goal Setting and Self-Monitoring

    Science.gov (United States)

    Peters, Erin E.

    2012-06-01

    Knowledge about the nature of science has been advocated as an important component of science because it provides a framework on which the students can incorporate content knowledge. However, little empirical evidence has been provided that links nature of science knowledge with content knowledge. The purpose of this mixed method study was to determine if both nature of science knowledge and content knowledge could be increased with an explicit, reflective nature of science intervention utilizing self-regulation over an implicit group. Results showed that the explicit group significantly outperformed the implicit group on both nature of science and content knowledge assessments. Students in the explicit group also demonstrated a greater use of detail in their inquiry work and reported a higher respect for evidence in making conclusions than the implicit group. Implications suggest that science educators could enhance nature of science instruction using goal setting and self-monitoring of student work during inquiry lessons.

  11. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2015-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  12. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2016-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  13. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition.

    Science.gov (United States)

    Wang, Hong; Taussig, Matthew D; DiPatrizio, Nicholas V; Bruce, Kimberley; Piomelli, Daniele; Eckel, Robert H

    2016-07-01

    We have previously reported that mice with neuron-specific LPL deficiency (NEXLPL-/-) become obese by 16weeks of age on chow. Moreover, these mice had reduced uptake of triglyceride (TG)-rich lipoprotein-derived fatty acids and lower levels of n-3 long chain polyunsaturated fatty acids (n-3 PUFAs) in the hypothalamus. Here, we asked whether increased dietary fat content or altered dietary composition could modulate obesity development in NEXLPL-/- mice. Male NEXLPL-/- mice and littermate controls (WT) were randomly assigned one of three synthetic diets; a high carbohydrate diet (HC, 10% fat), a high-fat diet (HF, 45% fat), or a HC diet supplemented with n-3 PUFAs (HCn-3, 10% fat, Lovaza, GSK®). After 42weeks of HC feeding, body weight and fat mass were increased in the NEXLPL-/- mice compared to WT. WT mice fed a HF diet displayed typical diet-induced obesity, but weight gain was only marginal in HF-fed NEXLPL-/- mice, with no significant difference in body composition. Dietary n-3 PUFA supplementation did not prevent obesity in NEXLPL-/- mice, but was associated with differential modifications in hypothalamic gene expression and PUFA concentration compared to WT mice. Our findings suggest that neuronal LPL is involved in the regulation of body weight and composition in response to either the change in quantity (HF feeding) or quality (n-3 PUFA-enriched) of dietary fat. The precise role of LPL in lipid sensing in the brain requires further investigation. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Content Documents Management

    Science.gov (United States)

    Muniz, R.; Hochstadt, J.; Boelke J.; Dalton, A.

    2011-01-01

    The Content Documents are created and managed under the System Software group with. Launch Control System (LCS) project. The System Software product group is lead by NASA Engineering Control and Data Systems branch (NEC3) at Kennedy Space Center. The team is working on creating Operating System Images (OSI) for different platforms (i.e. AIX, Linux, Solaris and Windows). Before the OSI can be created, the team must create a Content Document which provides the information of a workstation or server, with the list of all the software that is to be installed on it and also the set where the hardware belongs. This can be for example in the LDS, the ADS or the FR-l. The objective of this project is to create a User Interface Web application that can manage the information of the Content Documents, with all the correct validations and filters for administrator purposes. For this project we used one of the most excellent tools in agile development applications called Ruby on Rails. This tool helps pragmatic programmers develop Web applications with Rails framework and Ruby programming language. It is very amazing to see how a student can learn about OOP features with the Ruby language, manage the user interface with HTML and CSS, create associations and queries with gems, manage databases and run a server with MYSQL, run shell commands with command prompt and create Web frameworks with Rails. All of this in a real world project and in just fifteen weeks!

  15. The Development, Content, Design, and Conduct of the 2011 Piloted US DOE Nuclear Criticality Safety Program Criticality Safety Engineering Training and Education Project

    International Nuclear Information System (INIS)

    Hopper, Calvin Mitchell

    2011-01-01

    In May 1973 the University of New Mexico conducted the first nationwide criticality safety training and education week-long short course for nuclear criticality safety engineers. Subsequent to that course, the Los Alamos Critical Experiments Facility (LACEF) developed very successful 'hands-on' subcritical and critical training programs for operators, supervisors, and engineering staff. Since the inception of the US Department of Energy (DOE) Nuclear Criticality Technology and Safety Project (NCT and SP) in 1983, the DOE has stimulated contractor facilities and laboratories to collaborate in the furthering of nuclear criticality as a discipline. That effort included the education and training of nuclear criticality safety engineers (NCSEs). In 1985 a textbook was written that established a path toward formalizing education and training for NCSEs. Though the NCT and SP went through a brief hiatus from 1990 to 1992, other DOE-supported programs were evolving to the benefit of NCSE training and education. In 1993 the DOE established a Nuclear Criticality Safety Program (NCSP) and undertook a comprehensive development effort to expand the extant LACEF 'hands-on' course specifically for the education and training of NCSEs. That successful education and training was interrupted in 2006 for the closing of the LACEF and the accompanying movement of materials and critical experiment machines to the Nevada Test Site. Prior to that closing, the Lawrence Livermore National Laboratory (LLNL) was commissioned by the US DOE NCSP to establish an independent hands-on NCSE subcritical education and training course. The course provided an interim transition for the establishment of a reinvigorated and expanded two-week NCSE education and training program in 2011. The 2011 piloted two-week course was coordinated by the Oak Ridge National Laboratory (ORNL) and jointly conducted by the Los Alamos National Laboratory (LANL) classroom education and facility training, the Sandia National

  16. Objectively measured physical activity predicts hip and spine bone mineral content in children and adolescents ages 5 - 15 years: Iowa Bone Development Study

    Directory of Open Access Journals (Sweden)

    Kathleen F Janz

    2014-07-01

    Full Text Available This study examined the association between physical activity (PA and bone mineral content (BMC; g from middle childhood to middle adolescence and compared the impact of vigorous-intensity PA (VPA over moderate- to vigorous-intensity PA (MVPA. Participants from the Iowa Bone Development Study were examined at ages 5, 8, 11, 13, and 15 yr (n=369, 449, 452, 410, 307, respectively. MVPA and VPA (min/day were measured using ActiGraph accelerometers. Anthropometry was used to measure body size and somatic maturity. Spine BMC and hip BMC were measured via dual-energy x-ray absorptiometry. Sex-specific multi-level linear models were fit for spine BMC and hip BMC, adjusted for weight (kg, height (cm, linear age (yr, non-linear age (yr2, and maturity (pre peak height velocity vs. at/post peak height velocity. The interaction effects of PA×maturity and PA×age were tested. We also examined differences in spine BMC and hip BMC between the least (10th percentile and most (90th percentile active participants at each examination period. Results indicated that PA added to prediction of BMC throughout the 10-year follow-up, except MVPA did not predict spine BMC in females. Maturity and age did not modify the PA effect for males nor females. At age 5, the males at the 90th percentile for VPA had 8.5% more hip BMC than males in the 10th percentile for VPA. At age 15, this difference was 2.0%. Females at age 5 in the 90th percentile for VPA had 6.1% more hip BMC than those in the 10th percentile for VPA. The age 15 difference was 1.8%. VPA was associated with BMC at weight-bearing skeletal sites from childhood to adolescence, and the effect was not modified by maturity or age. Our findings indicate the importance of early and sustained interventions that focus on VPA. Approaches focused on MVPA may be inadequate for optimal bone health, particularly for females.

  17. Formulation of detailed consumables management models for the development (preoperational) period of advanced space transportation system. Volume 4: Flight data file contents

    Science.gov (United States)

    Zamora, M. A.

    1976-01-01

    The contents of the Flight Data File which constitute the data required by and the data generated by the Mission Planning Processor are presented for the construction of the timeline and the determination of the consumables requirements of a given mission.

  18. Multi-sensory Storytelling for Persons with Profound Intellectual and Multiple Disabilities : An Analysis of the Development, Content and Application in Practice

    NARCIS (Netherlands)

    ten Brug, Annet; van der Putten, Annette; Penne, Anneleen; Maes, Bea; Vlaskamp, Carla

    Background Multi-sensory storytelling (MSST) books are individualized stories, which involve sensory stimulation in addition to verbal text. Despite the frequent use of MSST in practice, little research is conducted into its structure, content and effectiveness. This study aims at the analysis of

  19. Lesson Development for English Learners in Content Area Settings: Key Considerations. Q&A with Sarah Catherine K. Moore, Ph.D. 2016 Educator Effectiveness Webinar Series

    Science.gov (United States)

    Moore, Sarah Catherine K.

    2016-01-01

    In this webinar, Dr. Sarah Catherine K. Moore, Program Director at the Center for Applied Linguistics, outlined factors for content area teachers to consider as they design and deliver lessons for mainstream classrooms that include English learner (EL) students. This Q&A addressed the questions participants had for Dr. Moore following the…

  20. A Case Study on Specialised Content Knowledge Development with Dynamic Geometry Software: The Analysis of Influential Factors and Technology Beliefs of Three Pre-Service Middle Grades Mathematics Teachers

    Science.gov (United States)

    Zambak, Vecihi S.; Tyminski, Andrew M.

    2017-01-01

    This study characterises the development of Specialised Content Knowledge (SCK) with dynamic geometry software (DGS) throughout a semester. The research employed a single-case study with the embedded units of three pre-service middle grades mathematics teachers. Qualitative data were collected, and factors affecting these three teachers' SCK…

  1. 菜用大豆籽粒发育过程中Vc及矿物质含量分析%Analysis on vitamin C and mineral content during seeds development process in vegetable soybean

    Institute of Scientific and Technical Information of China (English)

    陈华涛; 陈新; 袁星星; 顾和平; 张红梅; 崔晓艳

    2012-01-01

    [目的]了解菜用大豆籽粒发育过程中Vc及矿物质含量的变化规律,为优质菜用大豆的选育和生产提供理论依据.[方法]以熟期相近的9份菜用大豆品种为供试材料,在菜用大豆籽粒发育期分析籽粒Vc及钾、镁、钙、铁等矿物质元素的含量变化.[结果]随着菜用大豆籽粒的不断发育,其Vc含量呈先上升后下降的变化趋势,在花后50 d最高;钾元素含量呈一直下降的变化趋势,而钙元素含量呈逐渐上升的变化趋势;籽粒百粒鲜重、镁和铁元素平均含量呈现先上升后下降的变化趋势,其最高值出现在花后55 d.[结论]菜用大豆籽粒百粒鲜重、镁和铁、Vc含量的变化规律较相似,而钾和钙元素的含量变化规律有所不同.%[Objective]The present experiment was conducted to analyze the changes in vitamin C and mineral content during seeds development process in vegetable soybean to provide practical basis for high-quality vegetable soybean production. [Method]Nine vegetable soybean varieties with similar growth duration were used to analyze the contents of vitamin C (Vc), potassium (K) , magnesium (Mg), calcium (Ca) and iron (Fe) in seeds during seed development. [Result]With the development of seeds in vegetable soybean, 100-seed weight, Vc, Mg and Fe contents increased and then showed a decreasing trend. Vc content was found the highest at 50 days after flowering, while 100-seed weight, Mg and Fe contents were the highest at 55 days. The K content showed a declining trend, while Ca content showed an increasing trend. [Conclusion]The weight of 100 seeds, and Vc, Mg and Fe contents showed similar trends of change during seed development process, while K and Ca behaved differently. The results may provide the help in breeding programs tailored to develop fine vegetable soybean varieties.

  2. Moisture content measurement in paddy

    Science.gov (United States)

    Klomklao, P.; Kuntinugunetanon, S.; Wongkokua, W.

    2017-09-01

    Moisture content is an important quantity for agriculture product, especially in paddy. In principle, the moisture content can be measured by a gravimetric method which is a direct method. However, the gravimetric method is time-consuming. There are indirect methods such as resistance and capacitance methods. In this work, we developed an indirect method based on a 555 integrated circuit timer. The moisture content sensor was capacitive parallel plates using the dielectric constant property of the moisture. The instrument generated the output frequency that depended on the capacitance of the sensor. We fitted a linear relation between periods and moisture contents. The measurement results have a standard uncertainty of 1.23 % of the moisture content in the range of 14 % to 20 %.

  3. Content-based intermedia synchronization

    Science.gov (United States)

    Oh, Dong-Young; Sampath-Kumar, Srihari; Rangan, P. Venkat

    1995-03-01

    Inter-media synchronization methods developed until now have been based on syntactic timestamping of video frames and audio samples. These methods are not fully appropriate for the synchronization of multimedia objects which may have to be accessed individually by their contents, e.g. content-base data retrieval. We propose a content-based multimedia synchronization scheme in which a media stream is viewed as hierarchial composition of smaller objects which are logically structured based on the contents, and the synchronization is achieved by deriving temporal relations among logical units of media object. content-based synchronization offers several advantages such as, elimination of the need for time stamping, freedom from limitations of jitter, synchronization of independently captured media objects in video editing, and compensation for inherent asynchronies in capture times of video and audio.

  4. Development and Preliminary Face and Content Validation of the “Which Health Approaches and Treatments Are You Using?” (WHAT) Questionnaires Assessing Complementary and Alternative Medicine Use in Pediatric Rheumatology

    Science.gov (United States)

    Toupin April, Karine; Stinson, Jennifer; Boon, Heather; Duffy, Ciarán M.; Huber, Adam M.; Gibbon, Michele; Descarreaux, Martin; Spiegel, Lynn; Vohra, Sunita; Tugwell, Peter

    2016-01-01

    Objective Complementary and alternative medicine (CAM) is commonly used by children with juvenile idiopathic arthritis (JIA), yet no validated questionnaires assess that use. The objective of this study was to develop child self- and parent proxy-report questionnaires assessing CAM use and to determine the face and content validity of the “Which Health Approaches and Treatments are you using?” (WHAT) questionnaires in pediatric rheumatology. Methods A sequential phased mixed methods approach was used to develop the questionnaires. A Delphi Survey of 126 experts followed by an interdisciplinary consensus conference of 14 stakeholders in CAM, general pediatrics and pediatric rheumatology was held to develop consensus on the content of the questionnaires using a nominal group technique. To determine face and content validity of the questionnaires, two groups, including (a) a purposive sample of 22 children with JIA 8 to 18 years and their parents from the Children’s Hospital of Eastern Ontario and the Hospital for Sick Children, and (b) 21 Canadian pediatric rheumatology experts, participated in interviews. Participants were independently asked about the goal, understandability and comprehensiveness of the WHAT questionnaires, as well as the relevance of items. Results Consensus was reached on 17 items of the WHAT questionnaires. The domains found to be relevant were child’s CAM use, factors associated with CAM use, perceived impact of CAM use, and communication about CAM. A total of 15 items in the parent proxy-report questionnaire and 13 items in the child report questionnaire showed adequate content validity. Conclusions Consensus was reached by experts on the content of a pediatric CAM questionnaire. Face and content validity testing and modifications made to the WHAT questionnaires have helped ensure adequate preliminary validity for use in pediatric rheumatology. This constitutes the basis for further testing of these questionnaires in pediatric

  5. The caCORE Software Development Kit: Streamlining construction of interoperable biomedical information services

    Directory of Open Access Journals (Sweden)

    Warzel Denise

    2006-01-01

    Full Text Available Abstract Background Robust, programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources are challenging to construct. Such systems require the adoption of common information models, data representations and terminology standards as well as documented application programming interfaces (APIs. The National Cancer Institute (NCI developed the cancer common ontologic representation environment (caCORE to provide the infrastructure necessary to achieve interoperability across the systems it develops or sponsors. The caCORE Software Development Kit (SDK was designed to provide developers both within and outside the NCI with the tools needed to construct such interoperable software systems. Results The caCORE SDK requires a Unified Modeling Language (UML tool to begin the development workflow with the construction of a domain information model in the form of a UML Class Diagram. Models are annotated with concepts and definitions from a description logic terminology source using the Semantic Connector component. The annotated model is registered in the Cancer Data Standards Repository (caDSR using the UML Loader component. System software is automatically generated using the Codegen component, which produces middleware that runs on an application server. The caCORE SDK was initially tested and validated using a seven-class UML model, and has been used to generate the caCORE production system, which includes models with dozens of classes. The deployed system supports access through object-oriented APIs with consistent syntax for retrieval of any type of data object across all classes in the original UML model. The caCORE SDK is currently being used by several development teams, including by participants in the cancer biomedical informatics grid (caBIG program, to create compatible data services. caBIG compatibility standards are based upon caCORE resources, and thus the caCORE SDK has

  6. Visual Analysis of Weblog Content

    Energy Technology Data Exchange (ETDEWEB)

    Gregory, Michelle L.; Payne, Deborah A.; McColgin, Dave; Cramer, Nick O.; Love, Douglas V.

    2007-03-26

    In recent years, one of the advances of the World Wide Web is social media and one of the fastest growing aspects of social media is the blogosphere. Blogs make content creation easy and are highly accessible through web pages and syndication. With their growing influence, a need has arisen to be able to monitor the opinions and insight revealed within their content. In this paper we describe a technical approach for analyzing the content of blog data using a visual analytic tool, IN-SPIRE, developed by Pacific Northwest National Laboratory. We highlight the capabilities of this tool that are particularly useful for information gathering from blog data.

  7. A Genome-Wide Survey of the Microsatellite Content of the Globe Artichoke Genome and the Development of a Web-Based Database

    Science.gov (United States)

    Portis, Ezio; Portis, Flavio; Valente, Luisa; Moglia, Andrea; Barchi, Lorenzo; Lanteri, Sergio; Acquadro, Alberto

    2016-01-01

    The recently acquired genome sequence of globe artichoke (Cynara cardunculus var. scolymus) has been used to catalog the genome’s content of simple sequence repeat (SSR) markers. More than 177,000 perfect SSRs were revealed, equivalent to an overall density across the genome of 244.5 SSRs/Mbp, but some 224,000 imperfect SSRs were also identified. About 21% of these SSRs were complex (two stretches of repeats separated by artichoke accessions, as templates. PMID:27648830

  8. An Analysis of Learning Activities in a Technology Education Textbook for Teachers : Learning Process Based on Contents Framework and Learning Scene to Develop Technological Literacy

    OpenAIRE

    Yata, Chikahiko; Hamamoto, Kengo; Oguri, Takenori

    2014-01-01

    This study analyzed the learning activities in a textbook on technology education for teachers, in order to examine the learning processes and learning scenes detailed therein. Results of analyzing learning process, primary learning activity found each contents framework. Other learning activities designated to be related to complementary in learning process. Results of analyzing learning scene, 14 learning scenes, among them "Scene to recognize the impact on social life and progress of techn...

  9. Digital Content Strategies

    OpenAIRE

    Halbheer, Daniel; Stahl, Florian; Koenigsberg, Oded; Lehmann, Donald R

    2013-01-01

    This paper studies content strategies for online publishers of digital information goods. It examines sampling strategies and compares their performance to paid content and free content strategies. A sampling strategy, where some of the content is offered for free and consumers are charged for access to the rest, is known as a "metered model" in the newspaper industry. We analyze optimal decisions concerning the size of the sample and the price of the paid content when sampling serves the dua...

  10. Development of the spectrometric imaging apparatus of laser induced fluorescence from plants and estimation of chlorophyll contents of rice leaves; Laser reiki keiko sokutei sochi no kaihatsu to inehanai no chlorophyll ganryo no suitei

    Energy Technology Data Exchange (ETDEWEB)

    Nakaya, K.; Shoji, K.; Hanyu, H.

    1999-05-01

    Photosynthetic activity of plants is an important factor to assess the micrometeorological effect of plant canopy or to estimate the influence of circumstances such as water stress. Light illumination induces fluorescence from a leaf or suspension of chloroplasts. The red chlorophyll fluorescence had been used to determine the process of the electron transportation in photosynthetic reaction. The fluorescence source other than chlorophyll is not announced sufficiently, but is supposed to be useful to determine the contents of the substance corresponding to physiological response of plants. We developed a fluorescence imaging apparatus to observe spectrum and distribution of laser induced fluorescence from a leaf. Pulsed UV-laser (Nd:YAG) induced blue-green fluorescence and red chlorophyll fluorescence from a green leaf. The pulse modulated measuring light and CCD with image-intensifier (ICCD) enable to detect the fluorescence from plants under illumination. The laser induced fluorescence (LIF) spectra were investigated to estimate the chlorophyll contents in leaves of rice. During the greening course of dark grown etiolated rice leaves, chlorophyll contents were determined using the extraction of leaves and steady state LIF spectra were measured. As a result, the ratio of fluorescent intensity between blue-green and red peaks (F460/F740 and F510/F740) decreased in proportion to alteration of chlorophyll contents respectively. These fluorescence intensity ratios perform more precise estimation of higher chlorophyll contents of leaves than reported red chlorophyll fluorescence intensity ratio (F690/E740). (author)

  11. Multimedia content analysis

    CERN Document Server

    Ohm, Jens

    2016-01-01

    This textbook covers the theoretical backgrounds and practical aspects of image, video and audio feature expression, e.g., color, texture, edge, shape, salient point and area, motion, 3D structure, audio/sound in time, frequency and cepstral domains, structure and melody. Up-to-date algorithms for estimation, search, classification and compact expression of feature data are described in detail. Concepts of signal decomposition (such as segmentation, source tracking and separation), as well as composition, mixing, effects, and rendering, are discussed. Numerous figures and examples help to illustrate the aspects covered. The book was developed on the basis of a graduate-level university course, and most chapters are supplemented by problem-solving exercises. The book is also a self-contained introduction both for researchers and developers of multimedia content analysis systems in industry. .

  12. Content provision and multi-homing

    OpenAIRE

    Pires, Armando J. Garcia

    2015-01-01

    We analyze the effects of multi-homing consumers on content provision by media firms. We develop a model where media firms compete on content provision and advertising revenues, and consumers enjoy network effects from consuming content that other consumers also consume. Media firms have to choose if they are single-content or multi-content, and in the latter case how much content to offer. Competition for advertising revenues gives a two-sided market nature to our model, since advertisers pr...

  13. caCORE: a common infrastructure for cancer informatics.

    Science.gov (United States)

    Covitz, Peter A; Hartel, Frank; Schaefer, Carl; De Coronado, Sherri; Fragoso, Gilberto; Sahni, Himanso; Gustafson, Scott; Buetow, Kenneth H

    2003-12-12

    Sites with substantive bioinformatics operations are challenged to build data processing and delivery infrastructure that provides reliable access and enables data integration. Locally generated data must be processed and stored such that relationships to external data sources can be presented. Consistency and comparability across data sets requires annotation with controlled vocabularies and, further, metadata standards for data representation. Programmatic access to the processed data should be supported to ensure the maximum possible value is extracted. Confronted with these challenges at the National Cancer Institute Center for Bioinformatics, we decided to develop a robust infrastructure for data management and integration that supports advanced biomedical applications. We have developed an interconnected set of software and services called caCORE. Enterprise Vocabulary Services (EVS) provide controlled vocabulary, dictionary and thesaurus services. The Cancer Data Standards Repository (caDSR) provides a metadata registry for common data elements. Cancer Bioinformatics Infrastructure Objects (caBIO) implements an object-oriented model of the biomedical domain and provides Java, Simple Object Access Protocol and HTTP-XML application programming interfaces. caCORE has been used to develop scientific applications that bring together data from distinct genomic and clinical science sources. caCORE downloads and web interfaces can be accessed from links on the caCORE web site (http://ncicb.nci.nih.gov/core). caBIO software is distributed under an open source license that permits unrestricted academic and commercial use. Vocabulary and metadata content in the EVS and caDSR, respectively, is similarly unrestricted, and is available through web applications and FTP downloads. http://ncicb.nci.nih.gov/core/publications contains links to the caBIO 1.0 class diagram and the caCORE 1.0 Technical Guide, which provide detailed information on the present caCORE architecture

  14. Publishing and Revising Content

    Science.gov (United States)

    Editors and Webmasters can publish content without going through a workflow. Publishing times and dates can be set, and multiple pages can be published in bulk. Making an edit to published content created a revision.

  15. Applying Banks' Typology of Ethnic Identity Development and Curriculum Goals to Story Content, Classroom Discussion, and the Ecology of Classroom and Community: Phase One. Instructional Resource No. 24.

    Science.gov (United States)

    Tomlinson, Louise M.

    This instructional resource describes ways in which J. A. Banks' typology of the stages of ethnic identity development and related curriculum goals can be applied to literacy instruction. Banks' definitions of the stages of development and the curriculum goals for each stage are provided. Strategies for analyzing materials and developing relevant…

  16. Plasmaspheric electron content

    International Nuclear Information System (INIS)

    Hartmann, G.K.

    1978-01-01

    Measurements of the plasmaspheric electron content are reviewed with particular reference to the ATS-6 radio beacon experiment. From the review, it appears likely that measurement of the plasmaspheric electron content is the only one capable of monitoring electron fluxes continuously between L 1 and L 2. Some recent important results deduced from plasmaspheric electron content measurements are discussed

  17. Desenvolvimento de barras de cereais à base de aveia com alto teor de fibra alimentar Development of oat based cereal bars with high dietary fiber content

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Gutkoski

    2007-06-01

    and are a source of vitamins, minerals, fibers, proteins and complex carbohydrates. The objective of this work was to study the effect of dietary fiber concentration and sugar in cereal bars made of oats with a high dietary fiber content. In the research, oat flakes, bran and flour from cultivar UPFA 22, selected on the basis of the dietary fiber and beta-glucans content, were used. The ingredients were used in amounts defined in laboratory tests. The experiment was carried out using a central composite rotational design applicable to the response surface methodology (RSM, and the effects of the sugar syrup concentration (70, 75 and 80 °Brix and dietary fiber content in the formulation (12, 16 and 20% on the chemical composition, calorie value, water activity, microbiology and sensorial characteristics of the cereal bars were evaluated. The results were analyzed by multiple regression and the significant linear, quadratic and interaction terms were used in the second order mathematical model. The results showed that oats can be used as an ingredient when making cereals bars presenting an adequate texture, flavor and appearance. The oats used in the formulation makes cereal bars with high dietary fiber and beta-glucan content. The bars present acceptable sensorial properties, similar to the industrialized bars, with higher acceptability when made with average concentration of sugar and high dietary fiber content. The cereal bars present low water activity and are within sanitary specifications and can be stored for 60 days.

  18. Naturalising Representational Content

    Science.gov (United States)

    Shea, Nicholas

    2014-01-01

    This paper sets out a view about the explanatory role of representational content and advocates one approach to naturalising content – to giving a naturalistic account of what makes an entity a representation and in virtue of what it has the content it does. It argues for pluralism about the metaphysics of content and suggests that a good strategy is to ask the content question with respect to a variety of predictively successful information processing models in experimental psychology and cognitive neuroscience; and hence that data from psychology and cognitive neuroscience should play a greater role in theorising about the nature of content. Finally, the contours of the view are illustrated by drawing out and defending a surprising consequence: that individuation of vehicles of content is partly externalist. PMID:24563661

  19. Development and application of an enzyme-linked immunosorbent assay for specific detection of mangiferin content in various cultivars of Mangifera indica leaves using anti-mangiferin polyclonal antibody.

    Science.gov (United States)

    Yusakul, Gorawit; Kitirattrakarn, Wongsathorn; Tanwanichkul, Narunat; Tanaka, Hiroyuki; Putalun, Waraporn

    2012-04-01

    An enzyme-linked immunosorbent assay (ELISA) was developed for determining mangiferin content in plant samples using a polyclonal antibody (PAb) against mangiferin. The developed ELISA showed a full measurement range from 0.12 to 31.25 μg/mL mangiferin with a relative standard deviation (RSD) less than 6% for both intra- and interassay precision levels. The accuracy was determined by a percent recovery experiment at three concentration levels and it showed 97.8%-103.7% recovery in Mangifera indica leaf samples. The developed ELISA exhibited a high correlation value (R² = 0.992) with the standard high-performance liquid chromatography (HPLC) method in various mangiferin-containing plant samples. Our results suggest that the validated ELISA methodology using a PAb against mangiferin can be applied to determine mangiferin content with high specificity, rapidity and simplicity in various mangiferin-containing plant samples. The mangiferin content in the mature leaves of fifty M. indica cultivars were determined using the developed ELISA. The mangiferin contents ranged from 1.94 ± 0.13% to 13.79 ± 0.84% dry wt. The Thawai cultivar leaves contained the highest level of mangiferin (13.79 ± 0.84% dry wt), but it is a rare cultivar. The Namdokmai, which is more commonly cultivated in Thailand, contain 12.41 ± 0.60% dry wt mangiferin; therefore, this cultivar leaf was recommended as the source of raw material for the pharmaceutical, nutraceutical and cosmetic product industries. Currently, natural heath products are accepted worldwide for healthcare. Mangiferin-containing plants and products exhibit health benefits against oxidative stress-related diseases, such as cardiovascular diseases, cancer, dyslipidemia and diabetes. We have developed an ELISA with high specificity, rapidity and simplicity for the quality control of mangiferin-derived product production. Moreover, we found that the Namdokmai leaf, a Thai M. indica cultivar, was recommended as the source of raw

  20. Medical Oversight, Educational Core Content, and Proposed Scopes of Practice of Wilderness EMS Providers: A Joint Project Developed by Wilderness EMS Educators, Medical Directors, and Regulators Using a Delphi Approach.

    Science.gov (United States)

    Millin, Michael G; Johnson, David E; Schimelpfenig, Tod; Conover, Keith; Sholl, Matthew; Busko, Jonnathan; Alter, Rachael; Smith, Will; Symonds, Jennifer; Taillac, Peter; Hawkins, Seth C

    2017-01-01

    A disparity exists between the skills needed to manage patients in wilderness EMS environments and the scopes of practice that are traditionally approved by state EMS regulators. In response, the National Association of EMS Physicians Wilderness EMS Committee led a project to define the educational core content supporting scopes of practice of wilderness EMS providers and the conditions when wilderness EMS providers should be required to have medical oversight. Using a Delphi process, a group of experts in wilderness EMS, representing educators, medical directors, and regulators, developed model educational core content. This core content is a foundation for wilderness EMS provider scopes of practice and builds on both the National EMS Education Standards and the National EMS Scope of Practice Model. These experts also identified the conditions when oversight is needed for wilderness EMS providers. By consensus, this group of experts identified the educational core content for four unique levels of wilderness EMS providers: Wilderness Emergency Medical Responder (WEMR), Wilderness Emergency Medical Technician (WEMT), Wilderness Advanced Emergency Medical Technician (WAEMT), and Wilderness Paramedic (WParamedic). These levels include specialized skills and techniques pertinent to the operational environment. The skills and techniques increase in complexity with more advanced certification levels, and address the unique circumstances of providing care to patients in the wilderness environment. Furthermore, this group identified that providers having a defined duty to act should be functioning with medical oversight. This group of experts defined the educational core content supporting the specific scopes of practice that each certification level of wilderness EMS provider should have when providing patient care in the wilderness setting. Wilderness EMS providers are, indeed, providing health care and should thus function within defined scopes of practice and with

  1. Development of a preliminary database of digestate chemistry, heavy metal and pathogen content to assist in Alberta regulation compliance : final report

    Energy Technology Data Exchange (ETDEWEB)

    Eckford, R.; Gao, T.T.J. [Alberta Research Council, Edmonton, AB (Canada)

    2009-11-15

    An ongoing investigation is underway in Alberta to study the feasibility of designing biogas facilities that use various biowaste feedstocks or substrates. Digestate from biowaste substrates other than manure is currently designated as sewage sludge, thus presenting economical challenges to an emerging anaerobic digestion industry. Previous studies at the Alberta Research Council (ARC) have shown that elevated heavy metal content is found primarily in manure and slaughterhouse waste and not in general biowaste. The limited data from ARC does not give Alberta Environment enough information to set guidelines for handling the digestate generated from biogas plants using various biowastes. The first part of this document provided information on digestate chemistry. In order to set guidelines for the biogas industry, it discussed the levels of heavy metals, salts, as well as nitrogen, phosphorous and potassium in feedstock biowastes used for anaerobic digestion and the post-digestion digestates, separated liquids and solids. It also discussed levels and destruction of pathogens in biowaste during anaerobic digestion. The second part of this document included an evaluation of pathogens in biowaste and digestate. A small-scale study was conducted on undigested biowaste and effluent after anaerobic digestion of biowaste using the USEPA microbiology testing methods for fecal coliform and Salmonella for biosolids. 22 refs., 95 tabs.

  2. The contents of sesamol and related lignans in sesame, tahina and halva as determined by a newly developed polarographic and stripping voltammetric analysis

    Energy Technology Data Exchange (ETDEWEB)

    Tokusoglu, O.; Kocak, S.; Aycan, S.

    2009-07-01

    The contents of antioxidant lignans (Sesamol) in sesame, commercial formulations of tahina and halva, which are processed tahina foods, were determined by Differential Pulse Polarography (DPP) with a capillary hanging mercury drop electrode (HMDE). A platinum wire was used as the counter electrode and Ag/AgCl was the reference electrode. Samples have been analyzed by standard addition procedures and found to be quantitative (p<0.01). Due to the fact that sesamol is an oil-soluble phenolic compound , it was found in the oil levels of sesame, tahina and halvas. Sesame samples contained 51.05-56.46 % in oil whereas tahina samples contained 52.12-53.79 % in oil. The oil percentage of plain halva was found to be 28.79 - 30.13 % (p<0.01). Phenolic lignans sesamol in sesame was 0.26-0.32 mg/100g oil, whereas the sesamol in tahina was 10.98-12.33 mg/100g oil. The sesamol in commercial plain halva samples and the open marketed plain halva samples contained 8.24-9.12 mg/100g oil and 4.97 mg sesamol /100g oil, respectively (R{sup 2}=0.9999) (p<0.01). The proposed Differential Pulse Polarographic (DPP) method is a rapid, reproducible procedure for the simultaneous determination of phenolic lignans in sesame and food products with sesame. It provides an adequate, sensitive, quantitative detection of these nutraceuticals in the commercial food industry. (Author) 26 refs.

  3. The contents of sesamol and related lignans in sesame, tahina and halva as determined by a newly developed polarographic and stripping voltammetric analysis

    Directory of Open Access Journals (Sweden)

    2009-06-01

    Full Text Available The contents of antioxidant lignans (Sesamol in sesame, commercial formulations of tahina and halva, which are processed tahina foods, were determined by Differential Pulse Polarography (DPP with a capillary hanging mercury drop electrode (HMDE. A platinum wire was used as the counter electrode and Ag/AgCl was the reference electrode. Samples have been analyzed by standard addition procedures and found to be quantitative (p2=0.9999 (pSe determinó el contenido del lignano antioxidante (Sesamol en sésamo, formulaciones comerciales de tahina y halva, que es el producto procesado de tahina, por polarografía de pulsos diferencial (DPP con un capilar conteniendo un electrodo de gota de mercurio (HMDE. Un hilo de platino fué usado como el electrodo contador y Ag/AgCl como electrodo de referencia. Las muestras fueron analizadas por procedimientos de adición de patrones y se encontró que wl procedimiento era cuantitativo (p2= 0.9999 (p< 0.01. El método polarográfico propuesto (DPP es un método rápido y reproducible para la determinación simultánea de lignanos fenólicos en sésamo y otros productos alimentarios que contienen sésamo. Éste proporciona una detección cuantitativa adecuada y sensible de este compuesto nutraceútico en alimentos comerciales.

  4. Development of a technique using MCNPX code for determination of nitrogen content of explosive materials using prompt gamma neutron activation analysis method

    Energy Technology Data Exchange (ETDEWEB)

    Nasrabadi, M.N., E-mail: mnnasrabadi@ast.ui.ac.ir [Department of Nuclear Engineering, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan 81746-73441 (Iran, Islamic Republic of); Bakhshi, F.; Jalali, M.; Mohammadi, A. [Department of Nuclear Engineering, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan 81746-73441 (Iran, Islamic Republic of)

    2011-12-11

    Nuclear-based explosive detection methods can detect explosives by identifying their elemental components, especially nitrogen. Thermal neutron capture reactions have been used for detecting prompt gamma 10.8 MeV following radioactive neutron capture by {sup 14}N nuclei. We aimed to study the feasibility of using field-portable prompt gamma neutron activation analysis (PGNAA) along with improved nuclear equipment to detect and identify explosives, illicit substances or landmines. A {sup 252}Cf radio-isotopic source was embedded in a cylinder made of high-density polyethylene (HDPE) and the cylinder was then placed in another cylindrical container filled with water. Measurements were performed on high nitrogen content compounds such as melamine (C{sub 3}H{sub 6}N{sub 6}). Melamine powder in a HDPE bottle was placed underneath the vessel containing water and the neutron source. Gamma rays were detected using two NaI(Tl) crystals. The results were simulated with MCNP4c code calculations. The theoretical calculations and experimental measurements were in good agreement indicating that this method can be used for detection of explosives and illicit drugs.

  5. Content Analysis of Student Essays after Attending a Problem-Based Learning Course: Facilitating the Development of Critical Thinking and Communication Skills in Japanese Nursing Students.

    Science.gov (United States)

    Itatani, Tomoya; Nagata, Kyoko; Yanagihara, Kiyoko; Tabuchi, Noriko

    2017-08-22

    The importance of active learning has continued to increase in Japan. The authors conducted classes for first-year students who entered the nursing program using the problem-based learning method which is a kind of active learning. Students discussed social topics in classes. The purposes of this study were to analyze the post-class essay, describe logical and critical thinking after attended a Problem-Based Learning (PBL) course. The authors used Mayring's methodology for qualitative content analysis and text mining. In the description about the skills required to resolve social issues, seven categories were extracted: (recognition of diverse social issues), (attitudes about resolving social issues), (discerning the root cause), (multi-lateral information processing skills), (making a path to resolve issues), (processivity in dealing with issues), and (reflecting). In the description about communication, five categories were extracted: (simple statement), (robust theories), (respecting the opponent), (communication skills), and (attractive presentations). As the result of text mining, the words extracted more than 100 times included "issue," "society," "resolve," "myself," "ability," "opinion," and "information." Education using PBL could be an effective means of improving skills that students described, and communication in general. Some students felt difficulty of communication resulting from characteristics of Japanese.

  6. Content dependent information flow control

    DEFF Research Database (Denmark)

    Nielson, Hanne Riis; Nielson, Flemming

    2017-01-01

    Information flow control extends access control by not only regulating who is allowed to access what data but also the subsequent use of the data. Applications within communications systems require such information flow control to be dependent on the actual contents of the data. We develop...

  7. [The development of pollen grains and formation of pollen tubes in higher plants : I. Quantitative measurements of the DNA-content of generative and vegetative nuclei in the pollen grain and pollen tube of Petunia hybrida mutants].

    Science.gov (United States)

    Hesemann, C U

    1971-01-01

    The DNA-content of generative and vegetative nuclei in mature pollen grains of four Petunia hybrida mutants was determined by cytophotometry. In addition the DNA-content of generative and vegetative nuclei in the pollen tube of two of these four mutants (virescens-2 n and ustulata-2 n) was cytophotometrically measured.The DNA-values found in the generative nuclei indicate that the DNA-replication continues in the mature pollen grain and comes to an end only after the migration of the nuclei into the pollen tube. These data are in disagreement with the results of DNA-measurements described for a limited number of other species which all show completion of DNA-synthesis during the maturation stage of the pollen grains.The vegetative nuclei of the four Petunia mutants studied show significant differences in the onset of the degenerative phase. Extreme variation is manifested in the ustulata-2 n mutant in which the degeneration of nuclei may reach the final stage in the maturing pollen grain. However in this mutant vegetative nuclei with an unaltered DNA-content may also be demonstrated in the pollen tube. Some of the vegetative nuclei in the pollen tube of ustulata-2 n exhibit an increased amount of DNA which could be the result of differential DNA-replication in the vegetative nuclei. The decrease of the DNA-content in a certain fraction of the vegetative nuclei in the maturing pollen grain does not agree with observations made in other species by several authors who report DNA constancy until the pollen grain is fully mature.The data obtained from the analysis of the four Petunia hybrida mutants point to an important role of the vegetative nucleus in the development of the pollen tube. The Petunia hybrida mutants may be regarded as especially favourable material for investigations concerning the function of the vegetative cell in the development of the pollen grain and pollen tube.

  8. Development of a method to determine the total C-14 content in saturated salt solutions; Entwicklung eines Verfahrens zur Bestimmung von C-14{sub gesamt} in gesaettigten Salzloesungen

    Energy Technology Data Exchange (ETDEWEB)

    Lucks, C.; Prautsch, C. [Bundesamt fuer Strahlenschutz, Berlin (Germany)

    2016-07-01

    This two-step method described here for the determination of the total carbon-14 content in saturated salt solutions is divided in the analysis of the carbon-14 in the evaporable and the non-evaporable fraction. After driving off the inorganic carbon by acidification, the volatile carbon compounds and volatile decomposition products follow with rising temperature inside the sample vessel in a mild stream of oxygen to a tube furnace equipped with CuO catalyst for oxidizing the carbon compounds to CO{sub 2} at a temperature of 800 C. Water is condensed out with an intensive condenser and the released CO{sub 2} is absorbed in a wash bottle filled with sodium hydroxide. Similarly, an aliquot of the evaporation residue is put in the first zone of the tube furnace during the second step of the analysis. After heating the catalyst in the second zone of the furnace to 800 C the residue is heated stepwise to 800 C. By proceeding in this way, the non-volatile compounds are decomposed or oxidised in the oxygen stream and finally completely oxidized by the aid of the catalyst. The released CO{sub 2} is again absorbed in another wash bottle. The carbonate of each fraction is then precipitated as BaCO{sub 3} separately. Finally, the precipitate is washed, dried, finely grounded and covered with toluene scintillation cocktail for measurement in a LSC. The detection limit is about 0,2 Bq/l for a sample volume of 250 ml.

  9. Heavy metal contents in growth bands of Porites corals: Record of anthropogenic and human developments from the Jordanian Gulf of Aqaba

    International Nuclear Information System (INIS)

    Al-Rousan, Saber A.; Al-Shloul, Rashid N.; Al-Horani, Fuad A.; Abu-Hilal, Ahmad H.

    2007-01-01

    In order to assess pollutants and impact of environmental changes in the coastal region of the Jordanian Gulf of Aqaba, concentrations of six metals were traced through variations in 5 years growth bands sections of recent Porties coral skeleton. X-radiography showed annual growth band patterns extending back to the year 1925. Baseline metal concentrations in Porites corals were established using 35 years-long metal record from late Holocene coral (deposited in pristine environment) and coral from reef that is least exposed to pollution in the marine reserve in the Gulf of Aqaba. The skeleton samples of the collected corals were acid digested and analyzed for their Cd, Cu, Fe, Mn, Pb and Zn content using Flame Atomic Absorption Spectrophotometer (FAAS). All metal profiles (except Fe and Zn) recorded the same metal signature from recent coral (1925-2005) in which low steady baseline levels were displayed in growth bands older than 1965, similar to those obtained from fossil and unpolluted corals. Most metals showed dramatic increase (ranging from 17% to 300%) in growth band sections younger than 1965 suggesting an extensive contamination of the coastal area since the mid sixties. This date represents the beginning of a period that witnessed increasing coastal activities, constructions and urbanization. This has produced a significant reduction in coral skeletal extension rates. Results from this study strongly suggest that Porites corals have a high tendency to accumulate heavy metals in their skeletons and therefore can serve as proxy tools to monitor and record environmental pollution (bioindicators) in the Gulf of Aqaba

  10. Heavy metal contents in growth bands of Porites corals: Record of anthropogenic and human developments from the Jordanian Gulf of Aqaba

    Energy Technology Data Exchange (ETDEWEB)

    Al-Rousan, Saber A. [Marine Science Station, University of Jordan and Yarmouk University, P.O. Box 195, Aqaba 77110 (Jordan)], E-mail: s.rousan@ju.edu.jo; Al-Shloul, Rashid N. [Department of Earth and Environmental Science, Faculty of Science, Yarmouk University, Irbid 21163 (Jordan); Al-Horani, Fuad A. [Marine Science Station, University of Jordan and Yarmouk University, P.O. Box 195, Aqaba 77110 (Jordan); Abu-Hilal, Ahmad H. [Department of Earth and Environmental Science, Faculty of Science, Yarmouk University, Irbid 21163 (Jordan)

    2007-12-15

    In order to assess pollutants and impact of environmental changes in the coastal region of the Jordanian Gulf of Aqaba, concentrations of six metals were traced through variations in 5 years growth bands sections of recent Porties coral skeleton. X-radiography showed annual growth band patterns extending back to the year 1925. Baseline metal concentrations in Porites corals were established using 35 years-long metal record from late Holocene coral (deposited in pristine environment) and coral from reef that is least exposed to pollution in the marine reserve in the Gulf of Aqaba. The skeleton samples of the collected corals were acid digested and analyzed for their Cd, Cu, Fe, Mn, Pb and Zn content using Flame Atomic Absorption Spectrophotometer (FAAS). All metal profiles (except Fe and Zn) recorded the same metal signature from recent coral (1925-2005) in which low steady baseline levels were displayed in growth bands older than 1965, similar to those obtained from fossil and unpolluted corals. Most metals showed dramatic increase (ranging from 17% to 300%) in growth band sections younger than 1965 suggesting an extensive contamination of the coastal area since the mid sixties. This date represents the beginning of a period that witnessed increasing coastal activities, constructions and urbanization. This has produced a significant reduction in coral skeletal extension rates. Results from this study strongly suggest that Porites corals have a high tendency to accumulate heavy metals in their skeletons and therefore can serve as proxy tools to monitor and record environmental pollution (bioindicators) in the Gulf of Aqaba.

  11. Puff pastry with low saturated fat contents: The role of fat and dough physical interactions in the development of a layered structure

    NARCIS (Netherlands)

    Renzetti, S.; Harder, R. de; Jurgens, A.

    2015-01-01

    In puff pastry, fat and dough rheological behavior during sheeting control pastry dough development by formation of the layered structure which is essential for product quality. The aim of this work was to unravel the influence of fat and dough physical interactions during sheeting, as affected by

  12. Traces of Discourses and Governmentality within the Content and Implementation of the Western Australian Fundamental Movement Skills Programme (STEPS Professional Development)

    Science.gov (United States)

    Jefferson-Buchanan, Rachael

    2016-01-01

    Over the last 20 years or more, a plethora of movement programmes have been adopted within primary physical education in the UK and across Australia. One particular programme, Fundamental Movement Skills (STEPS Professional Development), became of interest to the researcher during her dual role as the UK Fundamental Movement Skills (FMS)…

  13. Assessing the Content and Quality of Commercially Available Reading Software Programs: Do They Have the Fundamental Structures to Promote the Development of Early Reading Skills in Children?

    Science.gov (United States)

    Grant, Amy; Wood, Eileen; Gottardo, Alexandra; Evans, Mary Ann; Phillips, Linda; Savage, Robert

    2012-01-01

    The current study developed a taxonomy of reading skills and compared this taxonomy with skills being trained in 30 commercially available software programs designed to teach emergent literacy or literacy-specific skills for children in preschool, kindergarten, and Grade 1. Outcomes suggest that, although some skills are being trained in a…

  14. Home media server content management

    Science.gov (United States)

    Tokmakoff, Andrew A.; van Vliet, Harry

    2001-07-01

    With the advent of set-top boxes, the convergence of TV (broadcasting) and PC (Internet) is set to enter the home environment. Currently, a great deal of activity is occurring in developing standards (TV-Anytime Forum) and devices (TiVo) for local storage on Home Media Servers (HMS). These devices lie at the heart of convergence of the triad: communications/networks - content/media - computing/software. Besides massive storage capacity and being a communications 'gateway', the home media server is characterised by the ability to handle metadata and software that provides an easy to use on-screen interface and intelligent search/content handling facilities. In this paper, we describe a research prototype HMS that is being developed within the GigaCE project at the Telematica Instituut . Our prototype demonstrates advanced search and retrieval (video browsing), adaptive user profiling and an innovative 3D component of the Electronic Program Guide (EPG) which represents online presence. We discuss the use of MPEG-7 for representing metadata, the use of MPEG-21 working draft standards for content identification, description and rights expression, and the use of HMS peer-to-peer content distribution approaches. Finally, we outline explorative user behaviour experiments that aim to investigate the effectiveness of the prototype HMS during development.

  15. Engaging expert communities in development of content of Russia’s regional geoportals (case study: “River basins in European Russia” geoportal)

    Science.gov (United States)

    Ermolaeva, P.

    2018-01-01

    The purpose of this study is to attract expert communities’ intellectual resources to the process of developing a geoportal entitled "River Basins in European Russia". The results of a survey of experts (n=100) have shown that more than half of respondents had used a variety of geoportals’ data in their professional life. Data on digital relief models, streamflows and landscape maps are of greatest interest. In order to obtain a comprehensive social and ecological analysis of the territory, experts have expressed interest in placing data on population in the basins and its density, the volume of used natural resources, and recreational zones on the designed geoportal. In practical sense, our study can be viewed as a fruitful ground for the development of upward vertical communication (from citizens to the government) and partially horizontal communication among citizens via their engagement in the environmental decision-making process.

  16. Carry-over effects modulated by salinity during the early ontogeny of the euryhaline crab Hemigrapsus crenulatus from the Southeastern Pacific coast: Development time and carbon and energy content of offspring.

    Science.gov (United States)

    Urzúa, Ángel; Bascur, Miguel; Guzmán, Fabián; Urbina, Mauricio

    2018-03-01

    Hemigrapsus crenulatus is a key species of coastal and estuarine ecosystems in the Southeastern Pacific and New Zealand. Since the gravid females-and their embryos-develop under conditions of variable salinity, we propose that low external salinity will be met with an increase in energy expenditures in order to maintain osmoregulation; subsequently, the use of energy reserves for reproduction will be affected. In this study, we investigate in H. crenulatus whether 1) the biomass and energy content of embryos is influenced by salinity experienced during oogenesis and embryogenesis and 2) how variation in the biomass and energy content of embryos affects larval energetic condition at hatching. Here at low salinity (5PSU), egg-bearing females experienced massive and frequent egg losses, and therefore the development of their eggs during embryogenesis was not completed. In turn, at intermediate and high salinity (15 and 30PSU) embryogenesis was completed, egg development was successful, and larvae were obtained. Consistently, larvae hatched from eggs produced and incubated at high salinity (30PSU) were larger, had higher dry weight, and had increased carbon content and energy than larvae hatched from eggs produced at intermediate salinity (15PSU). From these results, it is seen that the size and biomass of early life stages of H. crenulatus can be affected by environmental salinity experienced during oogenesis and embryogenesis, and this variation can then directly affect the energetic condition of offspring at birth. Therefore, this study reveals a "cascade effect" modulated by salinity during the early ontogeny. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Hydroponics: Content and Rationale

    Science.gov (United States)

    Ernst, Jeremy V.; Busby, Joe R.

    2009-01-01

    Technology education has the means of becoming the catalyst for integrated content and curricula, especially in core academic areas, such as science and mathematics, where it has been found difficult to incorporate other subject matter. Technology is diverse enough in nature that it can be addressed by a variety of content areas, serving as a true…

  18. Branded content infantil

    OpenAIRE

    Raúl RODRÍGUEZ-FERRÁNDIZ

    2017-01-01

    Reseña del libro Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes. Review of the book Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes.

  19. Branded content infantil

    Directory of Open Access Journals (Sweden)

    Raúl RODRÍGUEZ-FERRÁNDIZ

    2017-01-01

    Full Text Available Reseña del libro Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes. Review of the book Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes.

  20. Print advertising: vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.; Fransen, M.L.

    2012-01-01

    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  1. Print advertising : Vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.H.H.J.; Fransen, M.L.

    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  2. Qualitative Content Analysis

    OpenAIRE

    Satu Elo; Maria Kääriäinen; Outi Kanste; Tarja Pölkki; Kati Utriainen; Helvi Kyngäs

    2014-01-01

    Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studie...

  3. Social video content delivery

    CERN Document Server

    Wang, Zhi; Zhu, Wenwu

    2016-01-01

    This brief presents new architecture and strategies for distribution of social video content. A primary framework for socially-aware video delivery and a thorough overview of the possible approaches is provided. The book identifies the unique characteristics of socially-aware video access and social content propagation, revealing the design and integration of individual modules that are aimed at enhancing user experience in the social network context. The change in video content generation, propagation, and consumption for online social networks, has significantly challenged the traditional video delivery paradigm. Given the massive amount of user-generated content shared in online social networks, users are now engaged as active participants in the social ecosystem rather than as passive receivers of media content. This revolution is being driven further by the deep penetration of 3G/4G wireless networks and smart mobile devices that are seamlessly integrated with online social networking and media-sharing s...

  4. List of Content

    Directory of Open Access Journals (Sweden)

    IJRED Editorial

    2013-02-01

    Full Text Available CONTENTS OF ARTICLES PAGEPassive Design of Buildings for Extreme Weather EnvironmentS.N. Al-Zubaidy, S. Tokbolat, R. Tokpatayeva 1-11 Economic Impact of CDM Implementation through Alternate Energy Resource SubstitutionK.J. Sreekanth, S. Jayaraj, N. Sudarsan 13-18 Implications of Charcoal Briquette Produced by Local Communities on Livelihoods and Environment in Nairobi KenyaMary Njenga, A Yonemitsu, N Karanjaa, M Iiyama, J Kithinji, M Dubbeling C Sundberge, R R Jamnadass 19-29 A Novel Design of Multi-Chambered Biomass BatteryK. Sudhakar, R. Ananthakrishnan, A. Goyal, H.K. Darji 31-34 Power Quality Improvement Wind Energy System Using Cascaded Multilevel InverterJ.S. Sathiyanarayanan, A. S. Kumar 35-43 Solar PV Lighting and Studying after Sunset: Analysis of Micro-benefits in Off-grid Rural GhanaGeorge Y. Obeng 45-51 Innovative Green Technology for Sustainable Industrial Estate DevelopmentR. Hadiwijoyo, P Purwanto, Sudharto P Hadi 53-58 Empowering Distributed Solar PV Energy For Malaysian Rural Housing: Towards Energy Security And Equitability Of Rural CommunitiesN.A. Ahmad, H. Byrd 59-68

  5. TAxonomy of Self-reported Sedentary behaviour Tools (TASST) framework for development, comparison and evaluation of self-report tools: content analysis and systematic review.

    Science.gov (United States)

    Dall, P M; Coulter, E H; Fitzsimons, C F; Skelton, D A; Chastin, Sfm

    2017-04-08

    Sedentary behaviour (SB) has distinct deleterious health outcomes, yet there is no consensus on best practice for measurement. This study aimed to identify the optimal self-report tool for population surveillance of SB, using a systematic framework. A framework, TAxonomy of Self-reported Sedentary behaviour Tools (TASST), consisting of four domains (type of assessment, recall period, temporal unit and assessment period), was developed based on a systematic inventory of existing tools. The inventory was achieved through a systematic review of studies reporting SB and tracing back to the original description. A systematic review of the accuracy and sensitivity to change of these tools was then mapped against TASST domains. Systematic searches were conducted via EBSCO, reference lists and expert opinion. The inventory included tools measuring SB in adults that could be self-completed at one sitting, and excluded tools measuring SB in specific populations or contexts. The systematic review included studies reporting on the accuracy against an objective measure of SB and/or sensitivity to change of a tool in the inventory. The systematic review initially identified 32 distinct tools (141 questions), which were used to develop the TASST framework. Twenty-two studies evaluated accuracy and/or sensitivity to change representing only eight taxa. Assessing SB as a sum of behaviours and using a previous day recall were the most promising features of existing tools. Accuracy was poor for all existing tools, with underestimation and overestimation of SB. There was a lack of evidence about sensitivity to change. Despite the limited evidence, mapping existing SB tools onto the TASST framework has enabled informed recommendations to be made about the most promising features for a surveillance tool, identified aspects on which future research and development of SB surveillance tools should focus. International prospective register of systematic reviews (PROPSPERO)/CRD42014009851

  6. Method development and validation for simultaneous determination of IEA-R1 reactor’s pool water uranium and silicon content by ICP OES

    Science.gov (United States)

    Ulrich, J. C.; Guilhen, S. N.; Cotrim, M. E. B.; Pires, M. A. F.

    2018-03-01

    IPEN’s research reactor, IEA-R1, an open pool type research reactor moderated and cooled by light water. High quality water is a key factor in preventing the corrosion of the spent fuel stored in the pool. Leaching of radionuclides from the corroded fuel cladding may be prevented by an efficient water treatment and purification system. However, as a safety management policy, IPEN has adopted a water chemistry control which periodically monitors the levels of uranium (U) and silicon (Si) in the pool’s reactor, since IEA-R1 employs U3Si2-Al dispersion fuel. An analytical method was developed and validated for the determination of uranium and silicon by ICP OES. This work describes the validation process, in a context of quality assurance, including the parameters selectivity, linearity, quantification limit, precision and recovery.

  7. TV content analysis techniques and applications

    CERN Document Server

    Kompatsiaris, Yiannis

    2012-01-01

    The rapid advancement of digital multimedia technologies has not only revolutionized the production and distribution of audiovisual content, but also created the need to efficiently analyze TV programs to enable applications for content managers and consumers. Leaving no stone unturned, TV Content Analysis: Techniques and Applications provides a detailed exploration of TV program analysis techniques. Leading researchers and academics from around the world supply scientifically sound treatment of recent developments across the related subject areas--including systems, architectures, algorithms,

  8. Development of a Univariate Membrane-Based Mid-Infrared Method for Protein Quantitation and Total Lipid Content Analysis of Biological Samples

    Directory of Open Access Journals (Sweden)

    Ivona Strug

    2014-01-01

    Full Text Available Biological samples present a range of complexities from homogeneous purified protein to multicomponent mixtures. Accurate qualification of such samples is paramount to downstream applications. We describe the development of an MIR spectroscopy-based analytical method offering simultaneous protein quantitation (0.25–5 mg/mL and analysis of total lipid or detergent species, as well as the identification of other biomolecules present in biological samples. The method utilizes a hydrophilic PTFE membrane engineered for presentation of aqueous samples in a dried format compatible with fast infrared analysis. Unlike classical quantification techniques, the reported method is amino acid sequence independent and thus applicable to complex samples of unknown composition. By comparison to existing platforms, this MIR-based method enables direct quantification using minimal sample volume (2 µL; it is well-suited where repeat access and limited sample size are critical parameters. Further, accurate results can be derived without specialized training or knowledge of IR spectroscopy. Overall, the simplified application and analysis system provides a more cost-effective alternative to high-throughput IR systems for research laboratories with minimal throughput demands. In summary, the MIR-based system provides a viable alternative to current protein quantitation methods; it also uniquely offers simultaneous qualification of other components, notably lipids and detergents.

  9. What do the JAMA editors say when they discuss manuscripts that they are considering for publication? Developing a schema for classifying the content of editorial discussion.

    Science.gov (United States)

    Dickersin, Kay; Ssemanda, Elizabeth; Mansell, Catherine; Rennie, Drummond

    2007-09-25

    In an effort to identify previously unrecognized aspects of editorial decision-making, we explored the words and phrases that one group of editors used during their meetings. We performed an observational study of discussions at manuscript meetings at JAMA, a major US general medical journal. One of us (KD) attended 12 editorial meetings in 2003 as a visitor and took notes recording phrases from discussion surrounding 102 manuscripts. In addition, editors attending the meetings completed a form for each manuscript considered, listing the reasons they were inclined to proceed to the next step in publication and reasons they were not (DR attended 4/12 meetings). We entered the spoken and written phrases into NVivo 2.0. We then developed a schema for classifying the editors' phrases, using an iterative approach. Our classification schema has three main themes: science, journalism, and writing. We considered 2,463 phrases, of which 87 related mainly to the manuscript topic and were not classified (total 2,376 classified). Phrases related to science predominated (1,274 or 54%). The editors, most of whom were physicians, also placed major weight on goals important to JAMA's mission (journalism goals) such as importance to medicine, strategic emphasis for the journal, interest to the readership, and results (729 or 31% of phrases). About 16% (n = 373) of the phrases used related to writing issues, such as clarity and responses to the referees' comments. Classification of editorial discourse provides insight into editorial decision making and concepts that need exploration in future studies.

  10. What do the JAMA editors say when they discuss manuscripts that they are considering for publication? Developing a schema for classifying the content of editorial discussion

    Directory of Open Access Journals (Sweden)

    Rennie Drummond

    2007-09-01

    Full Text Available Abstract Background In an effort to identify previously unrecognized aspects of editorial decision-making, we explored the words and phrases that one group of editors used during their meetings. Methods We performed an observational study of discussions at manuscript meetings at JAMA, a major US general medical journal. One of us (KD attended 12 editorial meetings in 2003 as a visitor and took notes recording phrases from discussion surrounding 102 manuscripts. In addition, editors attending the meetings completed a form for each manuscript considered, listing the reasons they were inclined to proceed to the next step in publication and reasons they were not (DR attended 4/12 meetings. We entered the spoken and written phrases into NVivo 2.0. We then developed a schema for classifying the editors' phrases, using an iterative approach. Results Our classification schema has three main themes: science, journalism, and writing. We considered 2,463 phrases, of which 87 related mainly to the manuscript topic and were not classified (total 2,376 classified. Phrases related to science predominated (1,274 or 54%. The editors, most of whom were physicians, also placed major weight on goals important to JAMA's mission (journalism goals such as importance to medicine, strategic emphasis for the journal, interest to the readership, and results (729 or 31% of phrases. About 16% (n = 373 of the phrases used related to writing issues, such as clarity and responses to the referees' comments. Conclusion Classification of editorial discourse provides insight into editorial decision making and concepts that need exploration in future studies.

  11. What do the JAMA editors say when they discuss manuscripts that they are considering for publication? Developing a schema for classifying the content of editorial discussion

    Science.gov (United States)

    Dickersin, Kay; Ssemanda, Elizabeth; Mansell, Catherine; Rennie, Drummond

    2007-01-01

    Background In an effort to identify previously unrecognized aspects of editorial decision-making, we explored the words and phrases that one group of editors used during their meetings. Methods We performed an observational study of discussions at manuscript meetings at JAMA, a major US general medical journal. One of us (KD) attended 12 editorial meetings in 2003 as a visitor and took notes recording phrases from discussion surrounding 102 manuscripts. In addition, editors attending the meetings completed a form for each manuscript considered, listing the reasons they were inclined to proceed to the next step in publication and reasons they were not (DR attended 4/12 meetings). We entered the spoken and written phrases into NVivo 2.0. We then developed a schema for classifying the editors' phrases, using an iterative approach. Results Our classification schema has three main themes: science, journalism, and writing. We considered 2,463 phrases, of which 87 related mainly to the manuscript topic and were not classified (total 2,376 classified). Phrases related to science predominated (1,274 or 54%). The editors, most of whom were physicians, also placed major weight on goals important to JAMA's mission (journalism goals) such as importance to medicine, strategic emphasis for the journal, interest to the readership, and results (729 or 31% of phrases). About 16% (n = 373) of the phrases used related to writing issues, such as clarity and responses to the referees' comments. Conclusion Classification of editorial discourse provides insight into editorial decision making and concepts that need exploration in future studies. PMID:17894854

  12. Learning Content Management Systems

    Directory of Open Access Journals (Sweden)

    Tache JURUBESCU

    2008-01-01

    Full Text Available The paper explains the evolution of e-Learning and related concepts and tools and its connection with other concepts such as Knowledge Management, Human Resources Management, Enterprise Resource Planning, and Information Technology. The paper also distinguished Learning Content Management Systems from Learning Management Systems and Content Management Systems used for general web-based content. The newest Learning Content Management System, very expensive and yet very little implemented is one of the best tools that helps us to cope with the realities of the 21st Century in what learning concerns. The debates over how beneficial one or another system is for an organization, can be driven by costs involved, efficiency envisaged, and availability of the product on the market.

  13. Building and Contents Insurance.

    Science.gov (United States)

    Freese, William C.

    Insurance coverage of school buildings and contents is becoming increasingly difficult to obtain, and increases of 50 percent or more in the premium are not uncommon. Methods of reducing premium increases are outlined in this speech. (MLF)

  14. Selenium content of mushrooms.

    Science.gov (United States)

    Stijve, T

    1977-07-29

    The selenium contents of 83 species of wild mushrooms were determined by oxygen combustion of the sample, followed by conversion of selenite to bromopiazselenol and final estimation by electron capture gas-liquid chromatography. Selenium concentration were found to range from 0.012-20.0 mg/kg dry weight. Selenium content was species-dependent. High concentrations were found in Agaricaceae and in certain Boletaceae of the genus Tubiporus, whereas in Russulaceae, Amanitaceae and Cantharellaceae selenium-rich species were absent or rare. Ascomycetes and all mushrooms growing on wood had a very low selenium content. The highest selenium concentrations (up to 20 ppm) were found in Boletus (Tubiporus) edulis, a most popular edible mushroom. Analyses of various parts of carpophores of B. edulis, Suillus luteus and Amanita muscaria indicate that in all three species the stalk contains less selenium than the fleshy part of the cap. In Boletus and Suillus the highest selenium content was found in the tubes.

  15. Developing content for a mHealth intervention to promote postpartum retention in prevention of mother-to-child HIV transmission programs and early infant diagnosis of HIV: a qualitative study.

    Directory of Open Access Journals (Sweden)

    Thomas A Odeny

    Full Text Available Maternal attendance at postnatal clinic visits and timely diagnosis of infant HIV infection are important steps for prevention of mother-to-child transmission (PMTCT of HIV. We aimed to use theory-informed methods to develop text messages targeted at facilitating these steps.We conducted five focus group discussions with health workers and women attending antenatal, postnatal, and PMTCT clinics to explore aspects of women's engagement in postnatal HIV care and infant testing. Discussion topics were informed by constructs of the Health Belief Model (HBM and prior empirical research. Qualitative data were coded and analyzed according to the construct of the HBM to which they related. Themes were extracted and used to draft intervention messages. We carried out two stages of further messaging development: messages were presented in a follow-up focus group in order to develop optimal phrasing in local languages. We then further refined the messages, pretested them in individual cognitive interviews with selected health workers, and finalized the messages for the intervention.Findings indicated that brief, personalized, caring, polite, encouraging, and educational text messages would facilitate women bringing their children to clinic after delivery, suggesting that text messages may serve as an important "cue to action." Participants emphasized that messages should not mention HIV due to fear of HIV testing and disclosure. Participants also noted that text messages could capitalize on women's motivation to attend clinic for childhood immunizations.Applying a multi-stage content development approach to crafting text messages--informed by behavioral theory--resulted in message content that was consistent across different focus groups. This approach could help answer "why" and "how" text messaging may be a useful tool to support maternal and child health. We are evaluating the effect of these messages on improving postpartum PMTCT retention and infant

  16. Developing content for a mHealth intervention to promote postpartum retention in prevention of mother-to-child HIV transmission programs and early infant diagnosis of HIV: a qualitative study.

    Science.gov (United States)

    Odeny, Thomas A; Newman, Maya; Bukusi, Elizabeth A; McClelland, R Scott; Cohen, Craig R; Camlin, Carol S

    2014-01-01

    Maternal attendance at postnatal clinic visits and timely diagnosis of infant HIV infection are important steps for prevention of mother-to-child transmission (PMTCT) of HIV. We aimed to use theory-informed methods to develop text messages targeted at facilitating these steps. We conducted five focus group discussions with health workers and women attending antenatal, postnatal, and PMTCT clinics to explore aspects of women's engagement in postnatal HIV care and infant testing. Discussion topics were informed by constructs of the Health Belief Model (HBM) and prior empirical research. Qualitative data were coded and analyzed according to the construct of the HBM to which they related. Themes were extracted and used to draft intervention messages. We carried out two stages of further messaging development: messages were presented in a follow-up focus group in order to develop optimal phrasing in local languages. We then further refined the messages, pretested them in individual cognitive interviews with selected health workers, and finalized the messages for the intervention. Findings indicated that brief, personalized, caring, polite, encouraging, and educational text messages would facilitate women bringing their children to clinic after delivery, suggesting that text messages may serve as an important "cue to action." Participants emphasized that messages should not mention HIV due to fear of HIV testing and disclosure. Participants also noted that text messages could capitalize on women's motivation to attend clinic for childhood immunizations. Applying a multi-stage content development approach to crafting text messages--informed by behavioral theory--resulted in message content that was consistent across different focus groups. This approach could help answer "why" and "how" text messaging may be a useful tool to support maternal and child health. We are evaluating the effect of these messages on improving postpartum PMTCT retention and infant HIV testing in a

  17. Qualitative Content Analysis

    Directory of Open Access Journals (Sweden)

    Satu Elo

    2014-02-01

    Full Text Available Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studies, our own experiences, and methodological textbooks. Trustworthiness was described for the main qualitative content analysis phases from data collection to reporting of the results. We concluded that it is important to scrutinize the trustworthiness of every phase of the analysis process, including the preparation, organization, and reporting of results. Together, these phases should give a reader a clear indication of the overall trustworthiness of the study. Based on our findings, we compiled a checklist for researchers attempting to improve the trustworthiness of a content analysis study. The discussion in this article helps to clarify how content analysis should be reported in a valid and understandable manner, which would be of particular benefit to reviewers of scientific articles. Furthermore, we discuss that it is often difficult to evaluate the trustworthiness of qualitative content analysis studies because of defective data collection method description and/or analysis description.

  18. Taurine content of tissues of irradiated rats

    International Nuclear Information System (INIS)

    Akhalaya, M.Ya.; Bogatyrev, G.P.; Kudryashov, Yu.B.; Yartsev, E.I.

    1976-01-01

    The taurine content of tissues (liver, stomach, small intestine and spleen) of rats irradiated with doses of 700 and 450 rads has been studied. Phase changes have been found in the taurine content of radiosensitive tissues in the course of radiation injury development

  19. Construct Validation of Content Standards for Teaching

    Science.gov (United States)

    van der Schaaf, Marieke F.; Stokking, Karel M.

    2011-01-01

    Current international demands to strengthen the teaching profession have led to an increased development and use of professional content standards. The study aims to provide insight in the construct validity of content standards by researching experts' underlying assumptions and preferences when participating in a delphi method. In three rounds 21…

  20. Developing a predictive model for the energy content of goat milk as the basis for a functional unit formulation to be used in the life cycle assessment of dairy goat production systems.

    Science.gov (United States)

    Danieli, P P; Ronchi, B

    2018-02-01

    Recent reports on livestock environmental impact based on life cycle assessment (LCA) did not fully consider the case of the dairy goat. Assignment of an environmental impact (e.g. global warming potential) to a specific product needs to be related to the appropriate 'unitary amount' or functional unit (FU). For milk, the energy content may provide a common basis for a definition of the FU. To date, no ad hoc formulations for the FU of goat milk have been proposed. For these reasons, this study aimed to develop and test one or more predictive models (DPMs) for the gross energy (GE) content of goat milk, based on published compositional data, such as fat (F), protein, total solids (TS), solid non-fat matter (SNF), lactose (Lac) and ash. The DPMs were developed, selected and tested using a linear regression approach, as a meta-analysis (i.e. meta-regression) was not applicable. However, in the final stage, a control procedure for spurious findings was carried out using a Monte Carlo permutation test. Because several published predictive models (PPMs) for GE in cow milk and goat milk were found in the literature, they were tested on the same data set with which the DPMs were developed. The best-performing DPMs and PPMs were compared directly with a subset of the individual data retrieved from the literature. Overall, the paucity of direct measurements of the GE in goat milk was a limiting factor in collecting data from the literature; thus, only a small data set (n=26) was established, even though it was considered sufficiently representative of milks from different goat breeds. The three best PPMs based on F alone gave more biased estimates of the GE content of the goat milk than the three new DPMs based on F, F and SNF and F and TS, respectively. Accordingly, three different formulations of FU are proposed, depending on the availability of data including both F and TS (or F and SNF) or F alone. Even though several metrics can be used in defining the FU for milk to

  1. Digital Broadband Content: Digital Content Strategies and policies. OECD Digital Economy Papers, No. 119

    Science.gov (United States)

    OECD Publishing (NJ1), 2006

    2006-01-01

    The development of digital content raises new issues as rapid technological developments challenge existing business models and government policies. This OECD study identifies and discusses six groups of business and public policy issues and illustrates these with existing and potential OECD Digital Content Strategies and Policies: (1) Innovation…

  2. System of HPC content archiving

    Science.gov (United States)

    Bogdanov, A.; Ivashchenko, A.

    2017-12-01

    This work is aimed to develop a system, that will effectively solve the problem of storing and analyzing files containing text data, by using modern software development tools, techniques and approaches. The main challenge of storing a large number of text documents defined at the problem formulation stage, have to be resolved with such functionality as full text search and document clustering depends on their contents. Main system features could be described with notions of distributed multilevel architecture, flexibility and interchangeability of components, achieved through the standard functionality incapsulation in independent executable modules.

  3. Strategy development for enterprise content management

    NARCIS (Netherlands)

    Smits, M.T.; O'Callaghan, R.; vom Brocke, J.; Simons, A.

    2014-01-01

    Many organizations maintain a variety of systems and databases in a complex ad-hoc information infrastructure that does not fulfill the need for company-wide unstructured information management in business processes, business functions, and the extended enterprise. We present a framework and a

  4. Distance technology transfer course content development.

    Science.gov (United States)

    2013-06-01

    The Illinois Department of Transportation (IDOT) offers multiple technology transfer courses for engineering, : project design, and safety training for state and local agency personnel. These courses are often essential to the : agency mission. Becau...

  5. Towards Content Development For Institutional Digital Repository ...

    African Journals Online (AJOL)

    The growth in Information and Communication Technology has lead to the emergence of Institutional Digital Repository, a digital archive for the preservation and dissemination of institutional research outputs. Institutional Digital Repositories make possible global dissemination of research outputs through the use of the ...

  6. Deploying Content Management System to enhance State ...

    African Journals Online (AJOL)

    PROF. O. E. OSUAGWU

    2013-09-01

    Sep 1, 2013 ... Abstract. Governments across developing countries worldwide have the ... KEYWORDS: Content Management, E-governance, Model, Search engine, ICT. ..... Benchmarking E-government (2002): A Global Perspective, United.

  7. Factors stimulating content marketing

    Directory of Open Access Journals (Sweden)

    Naser Azad

    2016-02-01

    Full Text Available This paper presents an empirical investigation to determine factors influencing on content marketing in banking industry. The study designs a questionnaire consists of 40 questions in Likert scale and distributes it among 550 randomly selected regular customers of Bank Mellat in city of Tehran, Iran and 400 properly filled questionnaires are collected. Cronbach alphas for all components of the survey are well above desirable level. Using principle component analysis with Varimax rotation, the study has determined six factors influencing the most on content marketing including organization, details, having new ideas, quality, sensitivity and power while the last component contains only two subcomponents and is removed from the study.

  8. Content, Context & Connectivity Persuasive Interplay

    DEFF Research Database (Denmark)

    Sørensen, Christian Grund

    2013-01-01

    -supported research project under EACEA). In the development of this project several categories of content have been implemented in technology enhanced learning tools. These have been designed to support learning in different contexts and eventually the role of the connectivity of these learning objects and tools......The aim of this paper is to discuss the relationship between content, context and connectivity and suggesting a model of Dynamic Interplay. This is done in relation to a specific learning environment concerning cultural mediation, in casu the Kaj Munk Case of the EuroPLOT-project (an EU...... is discussed. Focus is here on The Kaj Munk Study Edition, The Conceptual Pond, Immersive Layers Design, and Generative Learning Objects (GLOs) which are applications affiliated with the Munk case. This paper explores the persuasive potential of the interplay between the different applications for the benefit...

  9. List of Content

    Directory of Open Access Journals (Sweden)

    Editor IJRED

    2014-05-01

    Full Text Available CONTENTS OF ARTICLES page Tin (II Chloride Catalyzed Esterification of High FFA Jatropha Oil: Experimental and Kinetics Study DOI: 10.14710/ijred.3.2.75-81 75-81 Ratna Dewi Kusumaningtyas, Prima Astuti Handayani, Rochmadi Rochmadi, Suryo Purwono, Arief Budiman   Utilization of Iles-Iles and Sorghum Starch for Bioethanol Production DOI: 10.14710/ijred.3.2.83-89 83-89 Kusmiyati Kusmiyati, Agus Sulistiyono   Premixed Combustion of Kapok (ceiba pentandra seed oil on Perforated Burner DOI: 10.14710/ijred.3.2.91-97 91-97 I.K.G. Wirawan, I.N.G. Wardana,        Rudy Soenoko, Slamet Wahyudi   Castor Seed from Melkasa Agricultural Research Centre, East Showa, Ethiopia and it’s biodiesel performance in Four Stroke Diesel Engine DOI: 10.14710/ijred.3. 3.2.99-105 99-105 Tesfahun Tegegne Akanawa, Haimanot Gebrehiwot Moges, Ramesh Babu, Daniel Bisrat   Economic feasibility of large scale PV water pumping applications utilizing real field data for a case study in Jordan DOI: 10.14710/ijred.3.2.107-117 107-117 Ibrahim Odeh   Development of Briquette from Coir Dust and Rice Husk Blend: An Alternative Energy Source DOI: 10.14710/ijred.3.2.119-123 119-123 Md. Hamidul Islam, Md. Mosharraf Hossain,Md. Abdul Momin   Performance, Emissions and Combustion Characteristics of a Single Cylinder Diesel Engine Fuelled with Blends of Jatropha Methyl Ester and Diesel DOI: 10.14710/ijred.3.2.125-131 125-131 Debasish Padhee, Hifjur Raheman   The characteristic changes of betung bamboo (Dendrocalamus asper pretreated by fungal pretreatment DOI: 10.14710/ijred.3.2.133-143 133-143 Widya Fatriasari, Wasrin Syafii, Nyoman J Wistara, Khaswar Syamsu, Bambang Prasetya   Influence of the Determination Methods of K and C Parameters on the Ability of Weibull Distribution to Suitably Estimate Wind Potential and Electric Energy DOI: 10.14710/ijred.3.2.145-154 145-154 Ruben M. Mouangue, Myrin Y. Kazet, Alexis Kuitche, Jean-Marie Ndjaka    

  10. Procedural Content Generation: Concepts and Related Works

    Directory of Open Access Journals (Sweden)

    MARIÑO, J. R. H.

    2016-12-01

    Full Text Available The digital games market is growing every year and game development is becoming increasingly complex. Thus, scalability in content generation may require the work of a team with hundreds of people. Procedural Content Generation (PCG comes as an alternative to decrease costs and accelerate the process of game production by creating content automatically or semi-automatically. This article presents some concepts and reviews works developed in PCG, aiming to provide a starting point for those interested in learning and going deeper in the subject of PCG for digital games.

  11. Characterization of Cloud Water-Content Distribution

    Science.gov (United States)

    Lee, Seungwon

    2010-01-01

    The development of realistic cloud parameterizations for climate models requires accurate characterizations of subgrid distributions of thermodynamic variables. To this end, a software tool was developed to characterize cloud water-content distributions in climate-model sub-grid scales. This software characterizes distributions of cloud water content with respect to cloud phase, cloud type, precipitation occurrence, and geo-location using CloudSat radar measurements. It uses a statistical method called maximum likelihood estimation to estimate the probability density function of the cloud water content.

  12. Trustworthy content push

    OpenAIRE

    Kuntze, Nicolai; Schmidt, Andreas U.

    2006-01-01

    Delivery of content to mobile devices gains increasing importance in industrial environments to support employees in the field. An important application are e-mail push services like the fashionable Blackberry. These systems are facing security challenges regarding data transport to, and storage of the data on the end user equipment. The emerging Trusted Computing technology offers new answers to these open questions.

  13. Tourist-created Content

    DEFF Research Database (Denmark)

    Munar, Ana Maria

    2011-01-01

    study of social media sites and destination brands, relying on qualitative research methods, content analysis and field research. Findings – Tourists are largely contributing to destination image formation, while avoiding the use of the formal elements of the brands. The most popular strategies used...

  14. Loser Generated Content

    DEFF Research Database (Denmark)

    Petersen, Søren Mørk

    2008-01-01

    In this article [ 1 ] some of the critical aspects of Web 2.0 are mapped in relation to labor and the production of user generated content. For many years the Internet was considered an apt technology for subversion of capitalism by the Italian post–Marxists. What we have witnessed, however...

  15. Content metamorphosis in synthetic holography

    International Nuclear Information System (INIS)

    Desbiens, Jacques

    2013-01-01

    A synthetic hologram is an optical system made of hundreds of images amalgamated in a structure of holographic cells. Each of these images represents a point of view on a three-dimensional space which makes us consider synthetic holography as a multiple points of view perspective system. In the composition of a computer graphics scene for a synthetic hologram, the field of view of the holographic image can be divided into several viewing zones. We can attribute these divisions to any object or image feature independently and operate different transformations on image content. In computer generated holography, we tend to consider content variations as a continuous animation much like a short movie. However, by composing sequential variations of image features in relation with spatial divisions, we can build new narrative forms distinct from linear cinematographic narration. When observers move freely and change their viewing positions, they travel from one field of view division to another. In synthetic holography, metamorphoses of image content are within the observer's path. In all imaging Medias, the transformation of image features in synchronisation with the observer's position is a rare occurrence. However, this is a predominant characteristic of synthetic holography. This paper describes some of my experimental works in the development of metamorphic holographic images.

  16. Development of a bioassay to quantify the ricin toxin content of castor bean (Ricinus communis L. seeds=Desenvolvimento de um bioensaio para quantificar o teor da toxina ricina em sementes de mamona (Ricinus communis L.

    Directory of Open Access Journals (Sweden)

    Dick Auld

    2012-10-01

    Full Text Available In this study, we developed a bioassay to quantify the ricin toxin content of castor bean seeds. Existing quantification methods do not always reflect actual toxicity of the seeds analyzed, which may present lower ricin content even though they are more toxic than seeds presenting a higher content of ricin. This is because these methods actually measure the addition of ricin RCA, which is a compound less toxic than pure ricin. We decided to use in this study, the nematode Caenorhabditis elegans, which has been widely used by the pharmaceutical industry. We tested two strains of C. elegans using different methods in 8 experiments. We examined 4 methods of extracting the ricin complex and 3 methods of exposing the nematodes. Among the nematode strains and ricin extraction methods tested, we concluded that the best strain for testing ricin toxicity was the strain called N2 and that the best method for ricin extraction was a rotating bath followed by centrifugation and exposing the nematodes in 24 well plates with a solution of nematodes extracted from the media with destilated waterexposing the nematodes in 24-well plates This method is inexpensive, quick and adequate for the selection of offspring with lower RIP content.Foi desenvolvido um bioensaio para quantificar o teor de ricina nas sementes de mamona. Os métodos de quantificação existentes não refletem a toxidez real das sementes analizadas, que pode mostrar um resultado de menor teor de ricina e ainda assim ser mais toxico do que as sementes que apresentaram teores maiores. Isto ocorre por que estes métodos medem alem da ricina a RCA, que é um composto menos tóxico que a ricina pura. Foi decidido utilizar neste estudo o nematoide Caenorhabditis elegans, que tem sido amplamente utilizado na industria farmacêutica. Foram testadas duas estirpes de C.elegans usadas em diferentes métodos contando com 8 experimentos distintos. nós examinamos 4 métodos de extração de ricina e 3 m

  17. Framework for Enabling User-Generated Content

    OpenAIRE

    Nilsson, Karin H

    2012-01-01

    User-generated content, UGC, is a modern topic today and refers to media and creative works created by Internet users and posted on the Internet. More and more application developers wants to offer sharing functionalities in their applications and on their websites. The alternatives of doing so today are to use UGC platforms API, like Facebook and Twitter, to upload the content to that specific platform or to implement the framework ShareKit that enables the user to share their content on mul...

  18. Content of Diabetes-Associated Autoantibodies against Islet Autoantigens (IA-2A, GADA, IAA and the Level of Different Cytokines in Children and Adolescents on the Pre-Clinical and Early Clinical Stages of Type 1 Diabetes Mellitus Development

    Directory of Open Access Journals (Sweden)

    V.V. Popova

    2015-03-01

    Full Text Available The article provides the data on the immunological mechanisms of type 1 diabetes mellitus (T1DM on the preclinical and early clinical stages of disease formation on the basis of studying the features of T1DM pathogenesis, monitoring the process of autoimmune destruction of insulin-producing β-cells by determining the content of diabetes-associated auto-antibodies (the incidence and titers dynamics, the study of the characteristics of cytokine secretion on the pre-clinical stage of T1DM development in children and adolescents. Introduction of new approaches to pre-clinical diagnosis of T1DM allowed determine the group of marker-positive children with burdened heredity and predictable risk of disease development. The study involved 450 healthy normoglycemic children and adolescents aged from 7 to 15 years old. It was revealed that 94 (26.7 % of 366 children with burdened hereditary by at least two-fold determination of DAAb had an increased DAAb titer, mainly GADA and IA-2A, the clinical debut of T1DM manifested in 49 (52.1 % of them from 6 months to 12 years (30.9 ± 3.2 months. T1DM developed in the same period in a child, that was 0.8 % of the 272 (73.3 % DAAb-negative children. There was determined a formula of combined incidence and values of simultaneously elevated DAAb titers to islet autoantigens, namely IA-2A + GADA, which are predictor of the duration of T1DM pre-clinical stage and debut occurrence. It has been also established a disturbance of cytokine production (increased level of pro-inflammatory cytokines IL-1α, IL-6 and FNO-α, IL-8 and IL-16 while reduced concentration of IL-4 in blood plasma as a key factor in the T1DM pathogenesis that causes the debut occurrence, and aggressiveness of its course.

  19. Content Marketing Practices in Finland

    OpenAIRE

    Suuronen, Toni

    2016-01-01

    The purpose of this study is to draw attention to increasingly important business phenomenon of content marketing. This paper defines content marketing, identifies its key elements and phases, and explores content marketing practices. The theorethical part is based on Pam Didner's 4P model that describes the stages of content marketing cycle: plan, produce, promote and perfect. The empirical part of the study is based on semi-structured interviews of seasoned content marketing professionals t...

  20. An Equilibrium Model of User Generated Content

    OpenAIRE

    Dae-Yong Ahn; Jason A. Duan; Carl F. Mela

    2011-01-01

    This paper considers the joint creation and consumption of content on user generated content platforms (e.g., reviews or articles, chat, videos, etc.). On these platforms, users' utilities depend upon the participation of others; hence, users' expectations regarding the participation of others on the site becomes germane to their own involvement levels. Yet these beliefs are often assumed to be fixed. Accordingly, we develop a dynamic rational expectations equilibrium model of joint consumpti...