WorldWideScience

Sample records for cabs

  1. Optical design of airport control tower cabs.

    Science.gov (United States)

    Carman, P D; Budde, H W

    1980-02-15

    A study has been made of optical aspects of airport control towers as part of a planned general optimization of control towers by Transport Canada. Problems found were reflections, glare, visual obstructions, identification of distant objects, and excessive solar heat. The study makes recommendations on cab shape, tower height, glazing, shades, sunglasses, binoculars, and internal lighting. Proper choice of cab shape (e.g., 30 degrees window inclination and 12-28 sides) provided effective control of reflections. Some plastic shades werefound to increase the risk of eye damage. Two tower cabs incorporating the recommendations have been built and were found to be satisfactory. PMID:20216882

  2. Highly flexible protein-peptide docking using CABS-dock

    OpenAIRE

    Ciemny, Maciej Pawel; Kurcinski, Mateusz; Kozak, Konrad Jakub; Kolinski, Andrzej; Kmiecik, Sebastian

    2016-01-01

    Protein-peptide molecular docking is a difficult modeling problem. It is even more challenging when significant conformational changes that may occur during the binding process need to be predicted. In this chapter, we demonstrate the capabilities and features of the CABS-dock server for flexible protein-peptide docking. CABS-dock allows highly efficient modeling of full peptide flexibility and significant flexibility of a protein receptor. During CABS-dock docking, the peptide folding and bi...

  3. 49 CFR 229.121 - Locomotive cab noise.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Locomotive cab noise. 229.121 Section 229.121... § 229.121 Locomotive cab noise. (a) Performance standards for locomotives. (1) When tested for static noise in accordance with paragraph (a)(3) of this section, all locomotives of each design or model...

  4. Clean Cities Case Study: Barwood Cab Fleet Study Summary

    International Nuclear Information System (INIS)

    Barwood Cab Fleet Study Summary is the second in a new series called''Alternative Fuel Information Case Studies,'' designed to present real-world experiences with alternative fuels to fleet managers and other industry stakeholders

  5. California Basin Studies (CaBS)

    International Nuclear Information System (INIS)

    The California Continental Borderland's present configuration dates from about 4 to 5 X 106 years Before Present (B.P.) and is the most recent of several configurations of the southern California margin that have evolved after the North America Plate over-rode the East Pacific Rise about 30 X 106 years ago. The present morphology is a series of two to three northwest-southeast trending rows of depressions separated by banks and insular ridges. Two inner basins, Santa Monica and San Pedro, have been the site for the Department of Energy-funded California Basin Study (CaBS) Santa Monica and San Pedro Basins contain post-Miocene sediment thicknesses of about 2.5 and 1.5 km respectively. During the Holocene (past 10,000 years) about 10-12 m have accumulated. The sediment entered the basin by one or a combination of processes including particle infall (mainly as bioaggregates) from surface waters, from nepheloid plumes (surface, mid-depths and near-bottom), from turbidity currents, mass movements, and to a very minor degree direct precipitation. In Santa Monica Basin, during the last century, particle infall and nepheloid plume transport have been the most common processes. The former dominates in the central basin floor in water depths from 900 to 945 m. where a characteristic silt-clay with a typical mean diameter of about 0.006 mm, phi standard deviation

  6. The cabABC Operon Essential for Biofilm and Rugose Colony Development in Vibrio vulnificus.

    Directory of Open Access Journals (Sweden)

    Jin Hwan Park

    2015-09-01

    Full Text Available A transcriptome analysis identified Vibrio vulnificus cabABC genes which were preferentially expressed in biofilms. The cabABC genes were transcribed as a single operon. The cabA gene was induced by elevated 3',5'-cyclic diguanylic acid (c-di-GMP and encoded a calcium-binding protein CabA. Comparison of the biofilms produced by the cabA mutant and its parent strain JN111 in microtiter plates using crystal-violet staining demonstrated that CabA contributed to biofilm formation in a calcium-dependent manner under elevated c-di-GMP conditions. Genetic and biochemical analyses revealed that CabA was secreted to the cell exterior through functional CabB and CabC, distributed throughout the biofilm matrix, and produced as the biofilm matured. These results, together with the observation that CabA also contributes to the development of rugose colony morphology, indicated that CabA is a matrix-associated protein required for maturation, rather than adhesion involved in the initial attachment, of biofilms. Microscopic comparison of the structure of biofilms produced by JN111 and the cabA mutant demonstrated that CabA is an extracellular matrix component essential for the development of the mature biofilm structures in flow cells and on oyster shells. Exogenously providing purified CabA restored the biofilm- and rugose colony-forming abilities of the cabA mutant when calcium was available. Circular dichroism and size exclusion analyses revealed that calcium binding induces CabA conformational changes which may lead to multimerization. Extracellular complementation experiments revealed that CabA can assemble a functional matrix only when exopolysaccharides coexist. Consequently, the combined results suggested that CabA is a structural protein of the extracellular matrix and multimerizes to a conformation functional in building robust biofilms, which may render V. vulnificus to survive in hostile environments and reach a concentrated infective dose.

  7. Consortium for Algal Biofuel Commercialization (CAB-COMM) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mayfield, Stephen P. [Univ. of California, San Diego, CA (United States)

    2015-12-04

    The Consortium for Algal Biofuel Commercialization (CAB-Comm) was established in 2010 to conduct research to enable commercial viability of alternative liquid fuels produced from algal biomass. The main objective of CAB-Comm was to dramatically improve the viability of algae as a source of liquid fuels to meet US energy needs, by addressing several significant barriers to economic viability. To achieve this goal, CAB-Comm took a diverse set of approaches on three key aspects of the algal biofuels value chain: crop protection; nutrient utilization and recycling; and the development of genetic tools. These projects have been undertaken as collaboration between six academic institutions and two industrial partners: University of California, San Diego; Scripps Institution of Oceanography; University of Nebraska, Lincoln; Rutgers University; University of California, Davis; Johns Hopkins University; Sapphire Energy; and Life Technologies.

  8. Active Noise Control of the Heavy Truck Interior Cab

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In order to control the noise of the heavy truck interior cab effectively, the active noise control methods are employed. First, an interior noise field test for the heavy truck is performed, and frequencies of interior noise of this vehicle are analyzed. According to the spectrum analysis of acquired noise signal, it is found out that the main frequencies of interior noise are less than 800Hz. Then the least squares lattice (LSL) algorithm is used as signal processing algorithm of the controller and a closed-loop control DSP system, based on TMS 320VC5416, is developed. The residual signal at driver's ear is used as feedback signal. Lastly, the developed ANC system is loaded into the heavy truck cab, and controlling the noise at driver's ear for that truck at different driving speeds is attempted. The noise control test results indicate that the cab interior noise is reduced averagely by 0.9 dBA at different driving speeds.

  9. Cab-sharing : An Effective, Door-to-Door, On-Demand Transportation Service

    OpenAIRE

    Gidofalvi, Gyözö; Pedersen, Torben Bach

    2007-01-01

    City transportation is an increasing problem. Public transportation is cost effective, but do not provide door-to-door transportation. This makes the far more expensive cabs attractive and scarce. This paper proposes a location–based Cab–Sharing Service (CSS), which reduces cab fare costs and effectively utilizes available cabs. The CSS accepts cab requests from mobile devices in the form of origin–destination pairs. Then it automatically groups closeby requests to minimize the cost, utilize ...

  10. 49 CFR 238.447 - Train operator's controls and power car cab layout.

    Science.gov (United States)

    2010-10-01

    ... employee regularly assigned to occupy a power car cab and any floor-mounted seat in the cab shall be: (1... 49 Transportation 4 2010-10-01 2010-10-01 false Train operator's controls and power car cab layout... Specific Requirements for Tier II Passenger Equipment § 238.447 Train operator's controls and power car...

  11. Low frequency sound reproduction in irregular rooms using CABS (Control Acoustic Bass System)

    DEFF Research Database (Denmark)

    Celestinos, Adrian; Nielsen, Sofus Birkedal

    irregular room model using the FDTD (Finite Difference Time Domain) method has been presented. CABS has been simulated in the irregular room model. Measurements of CABS in a real irregular room have been performed. The performance of CABS was affected by the irregular shape of the room due to the corner...

  12. 49 CFR 238.411 - Rear end structures of power car cabs.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Rear end structures of power car cabs. 238.411... II Passenger Equipment § 238.411 Rear end structures of power car cabs. The rear end structure of the cab of a power car shall be designed to include the following elements, or their structural...

  13. 49 CFR 238.409 - Forward end structures of power car cabs.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Forward end structures of power car cabs. 238.409... II Passenger Equipment § 238.409 Forward end structures of power car cabs. This section contains requirements for the forward end structure of the cab of a power car. (A conceptual implementation of this...

  14. MODEL RESEARCH OF THE ACIVE VIBROIZOLATION CABS MACHINE

    Directory of Open Access Journals (Sweden)

    Jerzy MARGIELEWICZ

    2014-03-01

    Full Text Available The study was carried out computer simulations of mechatronic model bridge crane, which is intended to theoretical evaluation of the possibility of eliminating the mechanical vibrations affecting the operator's cab driven machine. The model studies used fixed value control, the controlled variable is selected as the vertical displacement of the cab. Also included in the research model rheological model of the operator's body. We examined four overhead cranes with lifting capacity of 50T, which are classified in accordance with the directive of the European Union concerning the design of cranes, the four classes of cranes HC stiffness. The use of an active vibration isolation system in which distinguishes two negative feedback loops, very well eliminate mechanical vibration to the operator.

  15. CAB Abstracts: guia ràpida. Octubre 2012

    OpenAIRE

    Universitat de Barcelona. CRAI

    2012-01-01

    CAB Abstracts és una de les bases de dades més destacades en el camp de la biologia aplicada i altres matèries afins. Conté referències bibliogràfiques dels àmbits temàtics següents: agricultura, silvicultura, salut humana, nutrició humana, salut animal, gestió i conservació de recursos naturals, etc.

  16. CAB Abstracts: guia d'ús. Octubre 2012

    OpenAIRE

    Universitat de Barcelona. CRAI

    2012-01-01

    CAB Abstracts és una de les bases de dades més destacades en el camp de la biologia aplicada i altres matèries afins. Conté referències bibliogràfiques dels àmbits temàtics següents: agricultura, silvicultura, salut humana, nutrició humana, salut animal, gestió i conservació de recursos naturals, etc.

  17. Analysis of CAB/UTIL & IFE/PASS SEAT Switch%浅谈CAB/UTIL和IFE/PASS SEAT电门

    Institute of Scientific and Technical Information of China (English)

    郭佳

    2015-01-01

    B737NG飞机P5-13电源面板存在两种构型,“CAB/UTIL”和“IFE/PASS SEAT”属于新构型中的两个电门,本文在结合手册与实际现象的基础上,分析了这两个电门的功用,避免在将来的排故过程中走弯路。%There are two configurations of B737NG aircraft P5-13 power supply panel, the"CAB/UTIL" and"IFE/PASS SEAT"belong to the two switches in the new configuration, based on the combination of manual and actual phenomena, this paper analyzes the function of these switches, to avoid detours during troubleshooting in the future.

  18. Combination of 5α-reductase inhibitor with combined androgen blockade (CAB) as a novel cytoreductive regimen before prostate brachytherapy: Ultra-CAB.

    Science.gov (United States)

    Muro, Yusuke; Kosaka, Takeo; Mizuno, Ryuichi; Ohashi, Toshio; Shigematsu, Naoyuki; Oya, Mototsugu

    2015-01-01

    We report a first case of using a 5α-reductase inhibitor (5ARI) and combined androgen blockade (CAB) as a cytoreductive regimen before prostate brachytherapy. Prostate volume reduction with CAB is limited to approximately 40% in most cases, making it difficult to meet anatomical constraints to perform these procedures in cases with large prostate volume. With the added administration of 5ARI, further volume reduction can be expected. Here, we describe this cytoreductive regimen used in a 63 year-old prostate cancer patient who became eligible to receive brachytherapy after dutasteride (0.5 mg daily) was added to CAB and prostate volume reduction of 57% was achieved. PMID:26069888

  19. Operators' perception of comfort in two tractor cabs.

    Science.gov (United States)

    Ferrari, E; Cavallo, E

    2013-01-01

    Workspace characteristics affect the perceived comfort level of the operator and uncomfortable working conditions have been found to have a negative impact on productivity and safety. The comfort of the operator is increasingly recognized by manufacturers as a product's added value. Comfort can positively distinguish a product and increase its competitiveness. The concept of comfort is controversial, and a clear operational definition is missing. Nevertheless, it is widely accepted that comfort is a subjective phenomenon that can be evaluated by the final users. In this study, comfort aspects of the tractor workspace interior (i.e., the cab) were investigated. Users with various levels of expertise and two medium-power utility tractors of different brands were used in a 2 x 2 mixed-factorial experimental design. Participants were involved in a dynamic assessment of the cabs, and their opinions about the different workspaces were collected through a questionnaire. Additionally, objective measurements were taken on both tractors, and subjective data were compared with objective data. Results indicate significant differences in terms of the ease of locating and operating the controls (i.e., rear-mounted three-point linkage, hydraulic system, and power take-off), the ease of starting the tractor, the ease exiting the cab, the required level of concentration in executing the tasks, the adequacy of lateral visibility from the driving station, and the level of noise at the operator's position. This article provides guidance for improving the comfort of tractor workspace interiors. Agricultural machinery manufactures would benefit from research results, differentiating themselves from competitors. PMID:23600166

  20. Evaluation of a tractor cab using real-time aerosol counting instrumentation.

    Science.gov (United States)

    Hall, Ronald M; Heitbrink, William A; Reed, Laurence D

    2002-01-01

    Aerosol instrumentation was used to evaluate air infiltration into tractor cabs that are used to protect the agricultural worker during pesticide applications. Preliminary surveys were conducted on three different manufactured agriculture enclosures. The results of these preliminary surveys indicated that aerosols are entering the cab through leak sources or are being generated inside the cab. These results identified the need for in-depth field evaluations of tractor cabs to identify any leak sources. To evaluate the ability of tractor cabs to reduce operator air contaminant exposure, field evaluations were conducted on two tractor cabs. Specifically, we evaluated: 1) the particle size distribution and the effectiveness of the filter system; and 2) air infiltration into the cab. These evaluations were also conducted to demonstrate the ease and practicality of using optical particle counters to evaluate the ability of cabin filtration systems. Pesticide particle size distribution during an air blast spray operation was also evaluated during the study. The field tests were conducted on a John Deere 7000 series tractor cab (tractor manufacturer's cab) and a Nelson spraycab (retrofit cab). Both cabs were equipped with high efficiency particulate air (HEPA) filter media which were assumed to be 99.97 percent efficient at removing the test aerosol, atmospheric condensation nuclei. Thus, the major source of aerosols inside the cab was assumed to be leakage around filters at the seals. Using a portable dust monitor (PDM), the ratio of the outside to inside aerosol measurements was used to calculate a cab protection factor. During the evaluations, one PDM was placed inside the tractor cab (near the tractor operator) and one PDM was placed outside (near the air intake) to count particles. During the evaluations, the instruments were switched to prevent instrument bias from affecting the findings. The ratio of the two measurements (i.e., protection factor = outside

  1. CAB Abstracts: guia ràpida [text]. Curs 2015-16

    OpenAIRE

    Universitat de Barcelona. CRAI

    2016-01-01

    CAB Abstracts és una base de dades bibliogràfica compilada per CAB International (CABI). Conté informació dels àmbits temàtics següents: agricultura, silvicultura, salut humana, nutrició humana, salut animal, gestió i conservació de recursos naturals, etc.

  2. Low frequency sound reproduction in irregular rooms using CABS (Control Acoustic Bass System)

    DEFF Research Database (Denmark)

    Celestinos, Adrian; Nielsen, Sofus Birkedal

    2011-01-01

    Early investigations on low frequency sound reproduction in rectangular rooms using CABS (Controlled Acoustic Bass System) have shown good results on simulations and measurements in real rooms. CABS takes the advantage of having a rectangular room with parallel walls. By using two low frequency l...

  3. Combination of 5α-reductase inhibitor with combined androgen blockade (CAB) as a novel cytoreductive regimen before prostate brachytherapy: Ultra-CAB

    OpenAIRE

    Muro, Yusuke; Kosaka, Takeo; Mizuno, Ryuichi; Ohashi, Toshio; Shigematsu, Naoyuki; Oya, Mototsugu

    2015-01-01

    We report a first case of using a 5α-reductase inhibitor (5ARI) and combined androgen blockade (CAB) as a cytoreductive regimen before prostate brachytherapy. Prostate volume reduction with CAB is limited to approximately 40% in most cases, making it difficult to meet anatomical constraints to perform these procedures in cases with large prostate volume. With the added administration of 5ARI, further volume reduction can be expected. Here, we describe this cytoreductive regimen used in a 63 y...

  4. Low-temperature thermoelectric power of CaB6

    International Nuclear Information System (INIS)

    We report the results of measurements of the thermoelectric power S of stoichiometric CaB6 and vacancy-doped Ca1-δB6 between 5 and 300 K. The thermopower for both materials is surprisingly large at room temperature. Across the whole temperature range covered, S is negative and the temperature dependence is most probably dictated by band-structure effects. The phenomenological interpretation of our data involves a calculation of S(T), using the Boltzmann equation in the relaxation time approximation and assuming a band of defect states in proximity to the lower edge of the conduction band. Good agreement with our data is found by considering acoustic phonon and ionized impurity scattering for the electrons in the conduction band, which is well separated from the valence band. (author)

  5. Center for Advanced Biofuel Systems (CABS) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Kutchan, Toni M. [Donald Danforth Plant Science Center, St. Louis, MO (United States)

    2015-12-02

    One of the great challenges facing current and future generations is how to meet growing energy demands in an environmentally sustainable manner. Renewable energy sources, including wind, geothermal, solar, hydroelectric, and biofuel energy systems, are rapidly being developed as sustainable alternatives to fossil fuels. Biofuels are particularly attractive to the U.S., given its vast agricultural resources. The first generation of biofuel systems was based on fermentation of sugars to produce ethanol, typically from food crops. Subsequent generations of biofuel systems, including those included in the CABS project, will build upon the experiences learned from those early research results and will have improved production efficiencies, reduced environmental impacts and decreased reliance on food crops. Thermodynamic models predict that the next generations of biofuel systems will yield three- to five-fold more recoverable energy products. To address the technological challenges necessary to develop enhanced biofuel systems, greater understanding of the non-equilibrium processes involved in solar energy conversion and the channeling of reduced carbon into biofuel products must be developed. The objective of the proposed Center for Advanced Biofuel Systems (CABS) was to increase the thermodynamic and kinetic efficiency of select plant- and algal-based fuel production systems using rational metabolic engineering approaches grounded in modern systems biology. The overall strategy was to increase the efficiency of solar energy conversion into oils and other specialty biofuel components by channeling metabolic flux toward products using advanced catalysts and sensible design:1) employing novel protein catalysts that increase the thermodynamic and kinetic efficiencies of photosynthesis and oil biosynthesis; 2) engineering metabolic networks to enhance acetyl-CoA production and its channeling towards lipid synthesis; and 3) engineering new metabolic networks for the

  6. Measuring and modeling air exchange rates inside taxi cabs in Los Angeles, California

    Science.gov (United States)

    Shu, Shi; Yu, Nu; Wang, Yueyan; Zhu, Yifang

    2015-12-01

    Air exchange rates (AERs) have a direct impact on traffic-related air pollutant (TRAP) levels inside vehicles. Taxi drivers are occupationally exposed to TRAP on a daily basis, yet there is limited measurement of AERs in taxi cabs. To fill this gap, AERs were quantified in 22 representative Los Angeles taxi cabs including 10 Prius, 5 Crown Victoria, 3 Camry, 3 Caravan, and 1 Uplander under realistic driving (RD) conditions. To further study the impacts of window position and ventilation settings on taxi AERs, additional tests were conducted on 14 taxis with windows closed (WC) and on the other 8 taxis with not only windows closed but also medium fan speed (WC-MFS) under outdoor air mode. Under RD conditions, the AERs in all 22 cabs had a mean of 63 h-1 with a median of 38 h-1. Similar AERs were observed under WC condition when compared to those measured under RD condition. Under WC-MFS condition, AERs were significantly increased in all taxi cabs, when compared with those measured under RD condition. A General Estimating Equation (GEE) model was developed and the modeling results showed that vehicle model was a significant factor in determining the AERs in taxi cabs under RD condition. Driving speed and car age were positively associated with AERs but not statistically significant. Overall, AERs measured in taxi cabs were much higher than typical AERs people usually encounter in indoor environments such as homes, offices, and even regular passenger vehicles.

  7. Analysis of fatalities in extended cab pickup trucks using an estimating equation method.

    Science.gov (United States)

    Anderson, C L; Agran, P; Winn, D

    2000-01-01

    We compared the fatality risk for occupants of rear passenger seats in extended cab and crew cab pickup trucks to the fatality risk for front seat occupants of the same vehicles using the (US) Fatality Analysis Reporting System (FARS) for 1982-1997. A 10-digit truncated vehicle identification number was used to classify the pickup trucks. The data were analyzed with an estimating equation for data having few observations per stratum. We identified 549 extended cab pickup trucks with one or more occupants of rear passenger seats and one or more occupant deaths. Occupants of rear passenger seats had a fatality risk 43% lower than front seat occupants (95% confidence interval 32% to 52%), controlling for age, sex, and restraint use. Occupants of rear seats of extended cabs in compact pickup trucks did not experience any higher fatality risk (relative to front-seat occupants of the same vehicles) than rear seat occupants of extended cabs in full-size pickup trucks and large 4-door crew cabs. PMID:11558103

  8. Abscisic Acid Control of rbcS and cab Transcription in Tomato Leaves.

    Science.gov (United States)

    Bartholomew, D M; Bartley, G E; Scolnik, P A

    1991-05-01

    Leaves of tomato (Lycopersicon esculentum) plants grown in soil in which moisture was lowered from field capacity to levels approaching permanent wilting point show a 10-fold increase in abscisic acid (ABA) and a 60 to 70 percent decrease in rbcS and cab steady-state mRNA levels. As indicated by transcription run-on experiments, the effect occurs primarily at the transcriptional level. Similar water deficit had only a minor effect on ABA level and on rbcS and cab expression in leaves of sitiens, an ABA mutant of tomato. Expression of rbcL, the chloroplast gene coding for the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase, is not affected by water stress. Application of exogenous ABA results in decreased rbcS and cab expression in both wild-type and sitiens leaves. Analysis of the expression of individual members of the rbcS gene family indicates that under water-deficit conditions, expression derives primarily from only three of the five rbcS genes. Effects of dark adaptation and water deficit are additive for cab but not for rbcS expression. These results support the hypothesis that, at least under water-deficit conditions, ABA or a derivative thereof mediates a negative regulation of rbcS and cab transcription in tomato plants. PMID:16668167

  9. The ethanol response gene Cab45 can modulate the impairment elicited by ethanol and ultraviolet in PC12 cells

    Institute of Scientific and Technical Information of China (English)

    Yunfeng Zhu; Quanli Wang; Wangru Xu; Sha Li

    2008-01-01

    High consumption of ethanolic beverages facilitates neurodegeneration,but the mechanism of this process still remained elusive.Suppression subtractive hybridization (SSH) is a technique for detection of rare transcripts.With SSH approach,we identified one ethanol response gene Cab45,which was down-regulated by ethanol with time-dependent manner in B104 cells.The full-length sequence of Cab45 gene was obtained by 5'-RACE (5'Rapid Amplification of cDNA Ends) for the first time in rat.Based on the sequence of deduced amino acid of rat Cab45,the alignment was conducted with its counterparts in different species and displayed a high conservation.Using different tissues in rat and cell lines,Cab45 was characterized by a ubiquitous expression and differentiation dependent down-regulation.Given that ethanol facilitates some cell differentiation,we hypothesize that Cab45 is involved in ethanol-mediated differentiation.With transient transfection,the function of Cab45 was investigated by up-regulation and down-regulation in PC12 cells.Ethanol treatment and UV exposure were conducted subsequently and cell proliferations were detected by MTT (Methyl Thiazolyl Tetrazolium) approach.It revealed that the up-regulation of Cab45 modulated the impairment elicited by ethanol and UV in transfected cells.As a member of new calcium binding protein family,the exact role of Cab45 still remains unclear.

  10. The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity.

    Science.gov (United States)

    Su, Hong-Wei; Zhu, Jun-Hao; Li, Hao; Cai, Rong-Jun; Ealand, Christopher; Wang, Xun; Chen, Yu-Xiang; Kayani, Masood Ur Rehman; Zhu, Ting F; Moradigaravand, Danesh; Huang, Hairong; Kana, Bavesh D; Javid, Babak

    2016-01-01

    Although regulation of translation fidelity is an essential process(1-7), diverse organisms and organelles have differing requirements of translational accuracy(8-15), and errors in gene translation serve an adaptive function under certain conditions(16-20). Therefore, optimal levels of fidelity may vary according to context. Most bacteria utilize a two-step pathway for the specific synthesis of aminoacylated glutamine and/or asparagine tRNAs, involving the glutamine amidotransferase GatCAB(21-25), but it had not been appreciated that GatCAB may play a role in modulating mistranslation rates. Here, by using a forward genetic screen, we show that the mycobacterial GatCAB enzyme complex mediates the translational fidelity of glutamine and asparagine codons. We identify mutations in gatA that cause partial loss of function in the holoenzyme, with a consequent increase in rates of mistranslation. By monitoring single-cell transcription dynamics, we demonstrate that reduced gatCAB expression leads to increased mistranslation rates, which result in enhanced rifampicin-specific phenotypic resistance. Consistent with this, strains with mutations in gatA from clinical isolates of Mycobacterium tuberculosis show increased mistranslation, with associated antibiotic tolerance, suggesting a role for mistranslation as an adaptive strategy in tuberculosis. Together, our findings demonstrate a potential role for the indirect tRNA aminoacylation pathway in regulating translational fidelity and adaptive mistranslation. PMID:27564922

  11. 49 CFR 238.209 - Forward end structure of locomotives, including cab cars and MU locomotives.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Forward end structure of locomotives, including... SAFETY STANDARDS Specific Requirements for Tier I Passenger Equipment § 238.209 Forward end structure of locomotives, including cab cars and MU locomotives. (a)(1) The skin covering the forward-facing end of...

  12. Protection of the vehicle cab environment against bacteria, fungi and endotoxins in composting facilities.

    Science.gov (United States)

    Schlosser, O; Huyard, A; Rybacki, D; Do Quang, Z

    2012-06-01

    Microbial quality of air inside vehicle cabs is a major occupational health risk management issue in composting facilities. Large differences and discrepancies in protection factors between vehicles and between biological agents have been reported. This study aimed at estimating the mean protection efficiency of the vehicle cab environment against bioaerosols with higher precision. In-cab measurement results were also analysed to ascertain whether or not these protection systems reduce workers' exposure to tolerable levels. Five front-end loaders, one mobile mixer and two agricultural tractors pulling windrow turners were investigated. Four vehicles were fitted with a pressurisation and high efficiency particulate air (HEPA) filtration system. The four others were only equipped with pleated paper filter without pressurisation. Bacteria, fungi and endotoxins were measured in 72 pairs of air samples, simultaneously collected inside the cab and on the outside of the cab with a CIP 10-M sampler. A front-end loader, purchased a few weeks previously, fitted with a pressurisation and high efficiency particulate air (HEPA) filtration system, and with a clean cab, exhibited a mean protection efficiency of between 99.47% CI 95% [98.58-99.97%] and 99.91% [99.78-99.98%] depending on the biological agent. It is likely that the lower protection efficiency demonstrated in other vehicles was caused by penetration through the only moderately efficient filters, by the absence of pressurisation, by leakage in the filter-sealing system, and by re-suspension of particles which accumulated in dirty cabs. Mean protection efficiency in regards to bacteria and endotoxins ranged between 92.64% [81.87-97.89%] and 98.61% [97.41-99.38%], and between 92.68% [88.11-96.08%] and 98.43% [97.44-99.22%], respectively. The mean protection efficiency was the lowest when confronted with fungal spores, from 59.76% [4.19-90.75%] to 94.71% [91.07-97.37%]. The probability that in-cab exposure to fungi

  13. Physiological and Genetic Description of Dissimilatory Perchlorate Reduction by the Novel Marine Bacterium Arcobacter sp. Strain CAB

    OpenAIRE

    Carlström, Charlotte I.; Wang, Ouwei; Melnyk, Ryan A.; Bauer, Stefan; Lee, Joyce; Engelbrektson, Anna; Coates, John D.

    2013-01-01

    ABSTRACT A novel dissimilatory perchlorate-reducing bacterium (DPRB), Arcobacter sp. strain CAB, was isolated from a marina in Berkeley, CA. Phylogenetically, this halophile was most closely related to Arcobacter defluvii strain SW30-2 and Arcobacter ellisii. With acetate as the electron donor, strain CAB completely reduced perchlorate (ClO4 −) or chlorate (ClO3 −) [collectively designated (per)chlorate] to innocuous chloride (Cl−), likely using the perchlorate reductase (Pcr) and chlorite di...

  14. The daily life of a medium-size Data Centre. The CAB astronomical data center

    Science.gov (United States)

    Solano, Enrique

    2015-12-01

    The Centro de Astrobiología (CAB) Data Centre is the most important astronomical data centre managed by a Spanish institution. Among others, it contains the Gran Telescopio Canarias (GTC) and the Calar Alto (CAHA) scientific archives. Nevertheless, our activities go well beyond data curation. Generation of high level data products (reduced datasets, catalogues,...), knowledge transfer to other Spanish data centres, development of tools to publish astronomical data in VO-compliant archives and services, development of data mining and analysis tools for an optimum scientific exploitation of our data collections and collaboration with scientific groups with research lines using CAB archive data are some of the topics that will be described in this presentation.

  15. Hybrid modelling and damping collaborative optimisation of Five-suspensions for coupling driver-seat-cab system

    Science.gov (United States)

    Zhao, Leilei; Zhou, Changcheng; Yu, Yuewei; Yang, Fuxing

    2016-05-01

    For the complex structure and vibration characteristics of coupling driver-seat-cab system of trucks, there is no damping optimisation theory for its suspensions at present, which seriously restricts the improvement of vehicle ride comfort. Thus, in this paper, the seat suspension was regarded as 'the fifth suspension' of cab, the 'Five-suspensions' for this system was proposed. Based on this, using the mechanism modelling method, a 4 degree-of-freedom coupling driver-seat-cab system model was presented; then, by the tested cab suspensions excitation and seat acceleration response, its parameters identification mathematical model was established. Based on this, taking optimal ride comfort as target, its damping collaborative optimisation mathematical model was built. Combining the tested signals and a simulation model with the mathematical models of parameters identification and damping collaborative optimisation, a complete flow of hybrid modelling and damping collaborative optimisation of Five-suspensions was presented. With a practical example of seat and cab system, the damping parameters were optimised and validated by simulation and bench test. The results show that the model and method proposed are correct and reliable, providing a valuable reference for the design of seat suspension and cab suspensions.

  16. Sleeper Cab Climate Control Load Reduction for Long-Haul Truck Rest Period Idling

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J. A.; Kreutzer, C.; Adelman, S.; Yeakel, S.; Zehme, J.

    2015-04-29

    Annual fuel use for long-haul truck rest period idling is estimated at 667 million gallons in the United States. The U.S. Department of Energy’s National Renewable Energy Laboratory’s CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck climate control systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In order for candidate idle reduction technologies to be implemented at the original equipment manufacturer and fleet level, their effectiveness must be quantified. To address this need, a number of promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. For this study, load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, and conductive pathways. The technologies selected for a complete-cab package of technologies were “ultra-white” paint, advanced insulation, and advanced curtains. To measure the impact of these technologies, a nationally-averaged solar-weighted reflectivity long-haul truck paint color was determined and applied to the baseline test vehicle. Using the complete-cab package of technologies, electrical energy consumption for long-haul truck daytime rest period air conditioning was reduced by at least 35% for summer weather conditions in Colorado. The National Renewable Energy Laboratory's CoolCalc model was then used to extrapolate the performance of the thermal load reduction technologies nationally for 161 major U.S. cities using typical weather conditions for each location over an entire year.

  17. Flexible protein-peptide docking using CABS-dock with knowledge about the binding site

    OpenAIRE

    Kurcinski, Mateusz; Ciemny, Maciej Pawel; Blaszczyk, Maciej; Kolinski, Andrzej; Kmiecik, Sebastian

    2016-01-01

    Despite considerable efforts, structural prediction of protein-peptide complexes is still a very challenging task, mainly due to two reasons: high flexibility of the peptides and transient character of their interactions with proteins. Recently we have developed an automated web server CABS-dock (http://biocomp.chem.uw.edu.pl/CABSdock), which conducts flexible protein-peptide docking without any knowledge about the binding site. Our method allows for full flexibility of the peptide, whereas t...

  18. Antistaphylococcal Activity of CB-181963 (CAB-175), an Experimental Parenteral Cephalosporin

    OpenAIRE

    Hoellman, Dianne B.; Pankuch, Glenn A.; Appelbaum, Peter C.

    2004-01-01

    Among 265 methicillin-susceptible and -resistant staphylococci, CB-181963 (CAB-175) had a 50% minimum inhibitory concentration of 2 μg/ml and a 90% minimum inhibitory concentration of 4 μg/ml. All strains except two vancomycin-resistant S. aureus and 5 vancomycin-intermediate S. aureus strains were also susceptible to vancomycin and teicoplanin, and all were susceptible to linezolid, ranbezolid, tigecycline, and quinupristin-dalfopristin. Most methicillin-resistant strains were levofloxacin r...

  19. STUDY OF TRANSMISSION LINES EFFECT ON THE SYSTEM OPERATIONON OF CONTINUOUS AUTOMATIC CAB SIGNALLING

    OpenAIRE

    Hololobova, O.; Havryliuk, V.; Kovryhin, M.; Buriak, S.

    2014-01-01

    Purpose. To conduct an effect research of the electromagnetic field of high-voltage transmission lines (HVTL) (750 kV, 50 Hz) on the track circuits and continuous automatic cab signalling (CACS) with a signal current of 50 Hz in the areas of convergence and intersection with the transmission lines and to propose possible methods to improve noise immunity of CACS. Methodology. The measurements were performed both by means of car-laboratory and directly on rail lines. During the study the elect...

  20. Easy synthesis of CaB2O4 via pyrolysis of calcium fructoborate

    Directory of Open Access Journals (Sweden)

    Claudia Cecilia Wagner

    2008-12-01

    Full Text Available The investigation of the thermal behavior of calcium fructoborate samples of composition Ca(C6H10O6BO2.3.5H 2O showed that CaB2O4 is generated as the final solid pyrolysis residue. On the basis of these observations a new, very easy, synthetic procedure for the preparation of high purity samples of this calcium borate is proposed. The material was characterized by X ray powder diffractometry and IR spectroscopy.

  1. Low frequency sound field control for loudspeakers in rectangular rooms using CABS (Controlled Acoustical Bass System)

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2010-01-01

    Rectangular rooms are the most common shape for sound reproduction, but at low frequencies the reflections from the boundaries of the room cause large spatial variations in the sound pressure level.  Variations up to 30 dB are normal, not only at the room modes, but basically at all frequencies. As...... distribution in the room at low frequencies by using multiple loudspeakers together with an optimal placement of the loudspeakers.  At low frequencies CABS will create a plane wave from the front wall loudspeakers which will be absorbed by additional loudspeakers at the rear wall giving an almost homogeneous...

  2. Homogeneous preparation of cellulose acetate propionate (CAP) and cellulose acetate butyrate (CAB) from sugarcane bagasse cellulose in ionic liquid.

    Science.gov (United States)

    Huang, Kelin; Wang, Ben; Cao, Yan; Li, Huiquan; Wang, Jinshu; Lin, Weijiang; Mu, Chaoshi; Liao, Dankui

    2011-05-25

    Cellulose acetate butyrate (CAB) and cellulose acetate propionate (CAP) were prepared homogeneously in a 1-allyl-3-methylimidazolium chloride (AmimCl) ionic liquid system from sugarcane bagasse (SB). The reaction temperature, reaction time, and molar ratio of butyric (propionic) anhydride/anhydroglucose units in the cellulose affect the butyryl (B) or propionyl (P) content of CAB or CAP samples. The (13)C NMR data revealed the distribution of the substituents of CAB and CAP. The thermal stability of sugar cane bagasse cellulose was found by thermogravimetric analysis to have decreased after chemical modification. After reaction, the ionic liquid was effectively recycled and reused. This study provides a new way for high-value-added utilization of SB and realizing the objective of turning waste into wealth. PMID:21452895

  3. Integración de la unidad de dirección para el iCab2

    OpenAIRE

    Lara Sánchez, Gerardo

    2011-01-01

    El iCab (Intelligent Car Automobile) surge de un vehículo eléctrico de transporte al cual se le han realizado modificaciones hardware y software para el control automático de la plataforma (a través de un ordenador) o manual (por medio de un joystick y pedales). Las plataformas iCab integran un conjunto de elementos que les permiten interactuar y conocer el entorno. Estos sistemas que se le integran son: un láser, un sistema de visión estereoscópica y un sistema GPS con sensores i...

  4. Dikegulac-Sodium Effect on Micropropagation and Biochemical Parameters in the Cherry Rootstocks CAB-6P and Gisela 6

    OpenAIRE

    SARROPOULOU, VIRGINIA; DIMASSITHERIOU, Kortessa; Therios, Ioannis

    2014-01-01

    The effects of dikegulac-sodium (DS) alone and in combination with benzyladenine (BA) οn the morphogenetic and biochemical responses in the cherry rootstocks CAB-6P (Prunus cerasus L.) and Gisela 6 (Prunus cerasus x Prunus canescens) were investigated. In the CAB-6P rootstock, DS did not promote shoot proliferation whereas its application at 40, 120 and 150 μΜ suppressed shoot length. In the Gisela 6 rootstock, the number of shoots per explant and shoot proliferation rate were greater with 80...

  5. Electron dynamics in CaB6 induced by one- and two-color femtosecond laser

    International Nuclear Information System (INIS)

    We simulate nonlinear electron dynamics in CaB6 crystal within the framework of time-dependent density functional theory (TDDFT) under one-color femtosecond laser fields (400 nm, 800 nm) and two-color cases (400 nm+800 nm) with different relative phases of ϕ=0, ϕ=π/4, ϕ=π/2. The time-dependent Kohn–Sham equation (TDKS) is solved in real-time and real-space evolution scheme. We investigate the energy absorption and the electron excitation of CaB6 crystal in detail. Besides, the electron density distributions and occupations are shown after each external field ends. Computational results indicate that for one-color case, the excitation behaviors are distinct due to the different frequencies; for two-color laser, we adjust the phase and obtain the asymmetric field, which causes the change of the dynamics response comparing with the symmetric field. At the end of laser, the electron occupation is broadly distributed in the energy range of 2.4–42.4 eV, which means a high excitation rate in the narrow-gap semiconductor under intense laser field. The occurrence of the breakdown is also checked for each case in the Letter.

  6. embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation

    OpenAIRE

    Plinke, C.; Cox, H. S.; Zarkua, N.; Karimovich, H. A.; Braker, K; Diel, R; Rusch-Gerdes, S.; Feuerriegel, S; Niemann, S.

    2010-01-01

    Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key role, a significant number of phenotypically ethambutol-resistant strains do not carry mutations in this codon. Here, other mutations in the embCAB operon are suggested to be involved in resistance development.

  7. Controlled Acoustic Bass System (CABS) A Method to Achieve Uniform Sound Field Distribution at Low Frequencies in Rectangular Rooms

    DEFF Research Database (Denmark)

    Celestinos, Adrian; Nielsen, Sofus Birkedal

    2008-01-01

    The sound field produced by loudspeakers at low frequencies in small- and medium-size rectangular listening rooms is highly nonuniform due to the multiple reflections and diffractions of sound on the walls and different objects in the room. A new method, called controlled acoustic bass system (CABS...

  8. 75 FR 1179 - Passenger Equipment Safety Standards; Front End Strength of Cab Cars and Multiple-Unit Locomotives

    Science.gov (United States)

    2010-01-08

    ... Transportation (Secretary) convened a meeting of representatives from all sectors of the rail industry with the... Issues Identified for Future Rulemaking C. RSAC Overview D. Establishment of the Passenger Safety Working.... Accident History D. FRA and Industry Standards for Front End Frame Structures of Cab Cars and...

  9. Physiological and genetic description of dissimilatory perchlorate reduction by the novel marine bacterium Arcobacter sp. strain CAB.

    Science.gov (United States)

    Carlström, Charlotte I; Wang, Ouwei; Melnyk, Ryan A; Bauer, Stefan; Lee, Joyce; Engelbrektson, Anna; Coates, John D

    2013-01-01

    A novel dissimilatory perchlorate-reducing bacterium (DPRB), Arcobacter sp. strain CAB, was isolated from a marina in Berkeley, CA. Phylogenetically, this halophile was most closely related to Arcobacter defluvii strain SW30-2 and Arcobacter ellisii. With acetate as the electron donor, strain CAB completely reduced perchlorate (ClO4(-)) or chlorate (ClO3(-)) [collectively designated (per)chlorate] to innocuous chloride (Cl(-)), likely using the perchlorate reductase (Pcr) and chlorite dismutase (Cld) enzymes. When grown with perchlorate, optimum growth was observed at 25 to 30°C, pH 7, and 3% NaCl. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) preparations were dominated by free-swimming straight rods with 1 to 2 polar flagella per cell. Strain CAB utilized a variety of organic acids, fructose, and hydrogen as electron donors coupled to (per)chlorate reduction. Further, under anoxic growth conditions strain CAB utilized the biogenic oxygen produced as a result of chlorite dismutation to oxidize catechol via the meta-cleavage pathway of aerobic catechol degradation and the catechol 2,3-dioxygenase enzyme. In addition to (per)chlorate, oxygen and nitrate were alternatively used as electron acceptors. The 3.48-Mb draft genome encoded a distinct perchlorate reduction island (PRI) containing several transposases. The genome lacks the pcrC gene, which was previously thought to be essential for (per)chlorate reduction, and appears to use an unrelated Arcobacter c-type cytochrome to perform the same function. IMPORTANCE The study of dissimilatory perchlorate-reducing bacteria (DPRB) has largely focused on freshwater, mesophilic, neutral-pH environments. This study identifies a novel marine DPRB in the genus Arcobacter that represents the first description of a DPRB associated with the Campylobacteraceae. Strain CAB is currently the only epsilonproteobacterial DPRB in pure culture. The genome of strain CAB lacks the pcrC gene found in all

  10. Low-temperature thermal conductivity of CaB6 and EuB6

    International Nuclear Information System (INIS)

    The thermal conductivities of stoichiometric CaB6, vacancy-doped Ca1-δB6, and EuB6 have been measured between 6 and 300 K. All our data may be rather well described across the entire temperature regime covered on the basis of a Debye-type relaxation-time approximation and by assuming the concurring influence of various scattering channels on the mean free path of the phonons. An unusual and strong resonance in the scattering rate of the phonons of all investigated materials is attributed to a strong interaction between acoustic itinerant and localized modes, the latter arising from oscillations of the metal cations around their equilibrium position

  11. Challenges of establishing a Community Advisory Board (CAB in a low-income, low-resource setting: experiences from Bagamoyo, Tanzania

    Directory of Open Access Journals (Sweden)

    Shubis Kafuruki

    2009-06-01

    Full Text Available Abstract Objective Community Advisory Boards are now seen as standard practice for clinical vaccine and drug trials worldwide. In the past, most Community Advisory Boards (CABs were established by activists and lobbyists to monitor HIV/AIDS vaccine and drug trials in developed countries. In Africa the first CAB was established in Uganda in 1990 in conjunction with an HIV vaccine project and has since been followed by others in South Africa, Zimbabwe, and Kenya. In 2007, the Bagamoyo branch of the Ifakara Health Institute initiated the formation of a CAB. The aim was to properly educate and empower elected CAB members to become full partners in all research activities concerning the public within the Bagamoyo area. Methods and Results Beginning in 2007, staff visited each of the 24 villages within the study area to inform the communities about the proposed CAB and asked them to elect two individuals to represent their village on the CAB. The first attempt was hampered by community leaders selecting themselves, which led to inconsistent attendance, gender imbalance, and political infighting. New criteria for the selection of representatives were implemented to exclude governmental leaders, illiterate representatives and to promote a one-to-one gender balance. The newly appointed representatives underwent training and have participated in CAB meetings largely devoid of the negative issues previously encountered. Conclusion The successfully established CAB has led to improved relations with the community and facilitated the recruitment of study subjects. Our experiences show that, it is possible to establish a non-specific CAB in a low-income setting.

  12. Formation and Optical Properties of Ag Nanoparticles in CaB4O7–Ag2O and CaB4O7–Gd2O3–Ag2O Tetraborate Glasses

    Directory of Open Access Journals (Sweden)

    V.T. Adamiv

    2014-11-01

    Full Text Available Formation of Ag nanoparticles (NPs in the near-surface layer of CaB4O7–Ag2O and CaB4O7 –Gd2O3–Ag2O glasses by annealing in vacuum or in air is reported. It is concluded that annealing in vacuum does not necessary require the presence of reducing ions. Intensive plasmon absorption bands peaked at 403, 406 and 413.3 nm were observed in the absorption spectra of glasses with Ag NPs. Average radius of nanoparticles was calculated from the plasmon band half width and falls within 1.3-3.3 nm. It is concluded that calculated from normalized transmission spectra and absorption spectra the non-linear refractive index n2 increases due to the plasmon resonance in Ag NPs.

  13. Formation and Optical Properties of Ag Nanoparticles in CaB4O7–Ag2O and CaB4O7–Gd2O3–Ag2O Tetraborate Glasses

    OpenAIRE

    V.T. Adamiv; Ya.V. Burak; R.V. Gamernyk; R.M. Dutka; I.M. Teslyuk

    2014-01-01

    Formation of Ag nanoparticles (NPs) in the near-surface layer of CaB4O7–Ag2O and CaB4O7 –Gd2O3–Ag2O glasses by annealing in vacuum or in air is reported. It is concluded that annealing in vacuum does not necessary require the presence of reducing ions. Intensive plasmon absorption bands peaked at 403, 406 and 413.3 nm were observed in the absorption spectra of glasses with Ag NPs. Average radius of nanoparticles was calculated from the plasmon band half width and falls within 1.3-3.3 nm. It i...

  14. In vivo binding of hot pepper bZIP transcription factor CabZIP1 to the G-box region of pathogenesis-related protein 1 promoter

    International Nuclear Information System (INIS)

    We find that salicylic acid and ethephon treatment in hot pepper increases the expression of a putative basic/leucine zipper (bZIP) transcription factor gene, CabZIP1. CabZIP1 mRNA is expressed ubiquitously in various organs. The green fluorescent protein-fused transcription factor, CabZIP1::GFP, can be specifically localized to the nucleus, an action that is consistent with the presence of a nuclear localization signal in its protein sequence. Transient overexpression of the CabZIP1 transcription factor results in an increase in PR-1 transcripts level in Nicotiana benthamiana leaves. Using chromatin immunoprecipitation, we demonstrate that CabZIP1 binds to the G-box elements in native promoter of the hot pepper pathogenesis-related protein 1 (CaPR-1) gene in vivo. Taken together, our results suggest that CabZIP1 plays a role as a transcriptional regulator of the CaPR-1 gene

  15. PENGARUH PENERAPAN PRINSIP GOOD CORPORATE GOVERNANCE TERHADAP KINERJA KEUANGAN PERUSAHAAN PERUM PERUMNAS REGIONAL VII CAB. SULSEL I

    OpenAIRE

    MAULIDIAH. K, ANDI LINA

    2007-01-01

    (Andi Lina Maulidiah), Pengaruh Penerapan Prinsip Good Corporate Governance terhadap Kinerja Keuangan Kantor Perum Perumnas Regional VII Cab. Sulsel I (Pembimbing I : Dra. Hj. Nurlaeni, M.Si. Ak. Pembimbing II : Dra. Aini Indrijawati, M.Si, Ak) Keywords : good corporate governance, kinerja keuangan Good corporate governance (Corporate Governance) can be interpreted as a process and structure used by the organs of the company to enhance shareholder value and compa...

  16. "Dammed Taxi Cab"--How Silent Communication in Questionnaires Can Be Understood and Used to Give Voice to Children's Experiences

    Science.gov (United States)

    Alerby, E.; Kostenius, C.

    2011-01-01

    "Dammed taxi cab"--a 12-year-old boy wrote these words in the margins of a questionnaire, and within this paper they will serve as a point of departure for the discussion of the use of questionnaires as a way to voice children's experiences. The overall aim of this paper is to enable understanding of and discuss the use of questionnaires as a way…

  17. Optimization of a neutron transmission beamline applied to materials science for the CAB linear accelerator

    International Nuclear Information System (INIS)

    The Neutrons and Reactors Laboratory (NYR) of CAB (Centro Atomico Bariloche) is equipped with a linear electron accelerator (LINAC - Linear particle accelerator). This LINAC is used as a neutron source from which two beams are extracted to perform neutron transmission and dispersion experiments. Through these experiments, structural and dynamic properties of materials can be studied. The neutron transmission experiments consist in a collimated neutron beam which interacts with a sample and a detector behind the sample. Important information about the microstructural characteristics of the material can be obtained from the comparison between neutron spectra before and after the interaction with the sample. In the NYR Laboratory, cylindrical samples of one inch of diameter have been traditionally studied. Nonetheless, there is a great motivation for doing systematic research on smaller and with different geometries samples; particularly sheets and samples for tensile tests. Hence, in the NYR Laboratory it has been considered the possibility of incorporating a neutron guide into the existent transmission line. According to all mentioned above, the main objective of this work consisted in the optimization of the flight transmission tube optics of neutrons. This optimization not only improved the existent line but also contributed to an election criterion for the neutron guide acquisition.

  18. In-cab technologies : an eco-system that can improve efficiency and save you money

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, T. [Geotrac International Inc., Calgary, AB (Canada); Doherty, R. [Verigo Inc., Edmonton, AB (Canada); Clarotta, C. [Intermec Technologies Canada Ltd., Toronto, ON (Canada); Lamb, J. [Vistavu Solutions, Calgary, AB (Canada); Haber, T. [Telus Energy Sector Organization, Calgary, AB (Canada)

    2008-07-01

    Various in-cab technologies were presented by representative from leading oil and gas communications technology experts. The presentation included details of new aircard data and cell phone data plans as well as data modem plans developed for truck fleets by Geotrac International Incorporated. Details of the company's new high speed cellular modems and messaging and mapping systems designed specifically for oil and gas fleets were also presented. The systems were capable of measuring fuel consumption and idling times as well as calculating savings for up to 50 trucks. Details of a driver fatigue and alertness study were presented by Verigo Incorporated, who have developed a system using electronic on-board recorders and wireless logs designed to provide on-line auditing and reports. The presentation provided details of amounts of time saved using the wireless logging and inspection tools. Details of field ticketing, preventative maintenance programs, and unit cost and asset management software tools developed by Vistavu Solutions were presented. New fleet mobility strategies developed by Intermec were also presented. The company specializes in the construction of rugged hand-held computers built to military specifications. It was concluded that use of the computers can provide significant cost savings for oil and gas companies. tabs., figs.

  19. Field measurements of mixed exposure of operators to radioactive aerosol, gas and quartz in confinement of mining equipment cabs during open-pit mining of high-grade uranium ores

    International Nuclear Information System (INIS)

    A series of field measurements of miners mixed exposure to radon and daughters, uranium ore dust and respirable quartz, was conducted in an open-pit mine in Northern Saskatchewan during 1980-81. Control of radon gas levels in the mining equipment cabs is required. Dust may be reduced by minimizing the resuspension of dust from contaminated surfaces within the cabs

  20. Active low frequency sound field control in a listening room using CABS (Controlled Acoustic Bass System) will also reduce the sound transmitted to neighbour rooms

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    is possible at modal frequencies. For that reason the modal frequencies in the source room will also have big impact on the transmission to neighbour rooms. These low frequency resonance frequencies are very audible in the source room but also in neighbour rooms as a booming bass. CABS (Controlled...... Acoustic Bass System) is a time based room correction system for reproduced sound using loudspeakers. The system can remove room modes at low frequencies, by active cancelling the reflection from at the rear wall to a normal stereo setup. Measurements in a source room using CABS and in two neighbour rooms...

  1. PET neuroimaging studies of [(18)F]CABS13 in a double transgenic mouse model of Alzheimer's disease and nonhuman primates.

    Science.gov (United States)

    Liang, Steven H; Holland, Jason P; Stephenson, Nickeisha A; Kassenbrock, Alina; Rotstein, Benjamin H; Daignault, Cory P; Lewis, Rebecca; Collier, Lee; Hooker, Jacob M; Vasdev, Neil

    2015-04-15

    Fluorine-18 labeled 2-fluoro-8-hydroxyquinoline ([(18)F]CABS13) is a promising positron emission tomography (PET) radiopharmaceutical based on a metal chelator developed to probe the "metal hypothesis of Alzheimer's disease". Herein, a practical radiosynthesis of [(18)F]CABS13 was achieved by radiofluorination followed by deprotection of an O-benzyloxymethyl group. Automated production and formulation of [(18)F]CABS13 resulted in 19 ± 5% uncorrected radiochemical yield, relative to starting [(18)F]fluoride, with ≥95% chemical and radiochemical purities, and high specific activity (>2.5 Ci/μmol) within 80 min. Temporal PET neuroimaging studies were carried out in female transgenic B6C3-Tg(APPswe,PSEN 1dE9)85Dbo/J (APP/PS1) and age-matched wild-type (WT) B6C3F1/J control mice at 3, 7, and 10 months of age. [(18)F]CABS13 showed an overall higher uptake and retention of radioactivity in the central nervous system of APP/PS1 mice versus WT mice with increasing age. However, PET/magnetic resonance imaging in normal nonhuman primates revealed that the tracer had low uptake in the brain and rapid formation of a hydrophilic radiometabolite. Identification of more metabolically stable (18)F-hydroxyquinolines that can be readily accessed by the radiochemical strategy presented herein is underway. PMID:25776827

  2. Pepper CabZIP63 acts as a positive regulator during Ralstonia solanacearum or high temperature-high humidity challenge in a positive feedback loop with CaWRKY40.

    Science.gov (United States)

    Shen, Lei; Liu, Zhiqin; Yang, Sheng; Yang, Tong; Liang, Jiaqi; Wen, Jiayu; Liu, Yanyan; Li, Jiazhi; Shi, Lanping; Tang, Qian; Shi, Wei; Hu, Jiong; Liu, Cailing; Zhang, Yangwen; Lin, Wei; Wang, Rongzhang; Yu, Huanxin; Mou, Shaoliang; Hussain, Ansar; Cheng, Wei; Cai, Hanyang; He, Li; Guan, Deyi; Wu, Yang; He, Shuilin

    2016-04-01

    CaWRKY40 is known to act as a positive regulator in the response of pepper (Capsicum annuum) to Ralstonia solanacearum inoculation (RSI) or high temperature-high humidity (HTHH), but the underlying mechanism remains elusive. Herein, we report that CabZIP63, a pepper bZIP family member, participates in this process by regulating the expression of CaWRKY40. CabZIP63 was found to localize in the nuclei, be up-regulated by RSI or HTHH, bind to promoters of both CabZIP63(pCabZIP63) and CaWRKY40(pCaWRKY40), and activate pCabZIP63- and pCaWRKY40-driven β-glucuronidase expression in a C- or G-box-dependent manner. Silencing of CabZIP63 by virus-induced gene silencing (VIGS) in pepper plants significantly attenuated their resistance to RSI and tolerance to HTHH, accompanied by down-regulation of immunity- or thermotolerance-associated CaPR1, CaNPR1, CaDEF1, and CaHSP24. Hypersensitive response-mediated cell death and expression of the tested immunity- and thermotolerance-associated marker genes were induced by transient overexpression (TOE) of CabZIP63, but decreased by that of CabZIP63-SRDX. Additionally, binding of CabZIP63 to pCaWRKY40 was up-regulated by RSI or HTHH, and the transcript level of CaWRKY40 and binding of CaWRKY40 to the promoters of CaPR1, CaNPR1, CaDEF1 and CaHSP24 were up-regulated by TOE of CabZIP63. On the other hand, CabZIP63 was also up-regulated transcriptionally by TOE of CaWRKY40. The data suggest collectively that CabZIP63 directly or indirectly regulates the expression of CaWRKY40 at both the transcriptional and post-transcriptional level, forming a positive feedback loop with CaWRKY40 during pepper's response to RSI or HTHH. Altogether, our data will help to elucidate the underlying mechanism of crosstalk between pepper's response to RSI and HTHH. PMID:26936828

  3. Structural,Electronic Properties and Chemical Bonding of Borate Li4CaB2O6 under High Pressure:an Ab Initio Investigation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hong; TANG Jin; CHENG Xin-Lu

    2008-01-01

    We calculate structural,electromc properties and chemical bonding of borate Li4CaB2O6 under high pressure by means of the local density-functional pseudopotential approach.The equilibrium lattice constants,density of states,Mulliken population,bond lengths,bond angles as well as the pressure dependence of the band gap are presented.Analysis of the simulated high pressure band structure suggests that borate Li4CaB2O6 can be used as the semi-conductor optical material.Based on the Mulliken population analysis,it is found that the electron transfer of the Li atom is very different from that of other atoms in the studied range of high pressures.The charge populations of the Li atom decrease with the pressure up to 60GPa,then increase with the pressure.

  4. Ergonomics Study on Tractor Cab Based on Manikin%基于人体模型的拖拉机驾驶室人机工程学研究

    Institute of Scientific and Technical Information of China (English)

    梁海莎; 章倩; 朱思洪

    2012-01-01

    基于样机“黄海金马1024”型拖拉机驾驶室的数据,在Pro/E中建立了优化设计后的拖拉机驾驶室三维模型。利用CATIA软件中的HumanBuilder模块,编写了符合我国人体测量数据的中国人群文件程序,建立了我国拖拉机驾驶员的人体模型。在CATIA软件平台下,利用人体模型对拖拉机驾驶室人机工程学设计进行了研究,可为今后人机工程学在拖拉机驾驶室设计领域的应用研究提供参考依据。%Based on manikin according to the data of the "Huanghai Jinma 1204" type tractor cab, the paper built 3D model of the improved tractor cab in Pro/E, established Chinese population document program, and built Chinese tractor drivers' manikin with the tool "Human Builder" in CATIA. This paper mainly studies the tractor cab design based on ergonomics in CATIA with the created Chinese tractor driver manikin,and which can provide a reference for the further study in this area.

  5. In-vivo identification of direct electron transfer from Shewanella oneidensis MR-1 to electrodes via outer-membrane OmcA-MtrCAB protein complexes

    Energy Technology Data Exchange (ETDEWEB)

    Okamoto, Akihiro [Department of Applied Chemistry, School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Nakamura, Ryuhei, E-mail: nakamura@light.t.u-tokyo.ac.jp [Department of Applied Chemistry, School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Hashimoto, Kazuhito, E-mail: hashimoto@light.t.u-tokyo.ac.jp [Department of Applied Chemistry, School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); ERATO/JST, HASHIMOTO Light Energy Conversion Project (Japan)

    2011-06-30

    Graphical abstract: . Display Omitted Highlights: > Monolayer biofilm of Shewanella cells was prepared on an ITO electrode. > Extracellular electron transfer (EET) process was examined with series of mutants. > Direct ET was confirmed with outer-membrane-bound OmcA-MtrCAB complex. > The EET process was not prominently influenced by capsular polysaccharide. - Abstract: The direct electron-transfer (DET) property of Shewanella bacteria has not been resolved in detail due to the complexity of in vivo electrochemistry in whole-cell systems. Here, we report the in vivo assignment of the redox signal indicative of the DET property in biofilms of Shewanella oneidensis MR-1 by cyclic voltammetry (CV) with a series of mutants and a chemical marking technique. The CV measurements of monolayer biofilms formed by deletion mutants of c-type cytochromes ({Delta}mtrA, {Delta}mtrB, {Delta}mtrC/{Delta}omcA, and {Delta}cymA), and pilin ({Delta}pilD), capsular polysaccharide ({Delta}SO3177) and menaquinone ({Delta}menD) biosynthetic proteins demonstrated that the electrochemical redox signal with a midpoint potential at 50 mV (vs. SHE) was due to an outer-membrane-bound OmcA-MtrCAB protein complex of decaheme cytochromes, and did not involve either inner-membrane-bound CymA protein or secreted menaquinone. Using the specific binding affinity of nitric monoxide for the heme groups of c-type cytochromes, we further confirmed this conclusion. The heterogeneous standard rate constant for the DET process was estimated to be 300 {+-} 10 s{sup -1}, which was two orders of magnitude higher than that previously reported for the electron shuttling process via riboflavin. Experiments using a mutant unable to produce capsular polysaccharide ({Delta}SO3177) revealed that the DET property of the OmcA-MtrCAB complex was not influenced by insulating and hydrophilic extracellular polysaccharide. Accordingly, under physiological conditions, S. oneidensis MR-1 utilizes a high density of outer

  6. Low frequency sound field control in rectangular listening rooms using CABS (Controlled Acoustic Bass System) will also reduce sound transmission to neighbor rooms

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2011-01-01

    Sound reproduction is often taking place in small and medium sized rectangular rooms. As rectangular rooms have 3 pairs of parallel walls the reflections at especially low frequencies will cause up to 30 dB spatial variations of the sound pressure level in the room. This will take place not only at...... resonance frequencies, but more or less at all frequencies. A time based room correction system named CABS (Controlled Acoustic Bass System) has been developed and is able to create a homogeneous sound field in the whole room at low frequencies by proper placement of multiple loudspeakers. A normal setup...

  7. Optimizacion de una linea de espectrometria neutronica de transmision aplicada a ciencia de materiales para el acelerador lineal del CAB

    International Nuclear Information System (INIS)

    The Neutrons and Reactors Laboratory (NYR) of CAB (Centro Atomico Bariloche) is equipped with a linear electron accelerator (LINAC) Linear particle accelerator). This LINAC is used as a neutron source from which two beams are extracted to perform neutron transmission and dispersion experiments. Through these experiments, structural and dynamic properties of materials can be studied. The neutron transmission experiments consist in a collimated neutron beam which interacts with a sample and a detector behind the sample. Important information about the microstructural characteristics of the material can be obtained from the comparison between neutron spectra before and after the interaction with the sample. This experimental technique has been extensively used to determine cross sections, lattice parameters of a crystalline solid, vibration frequencies of atoms or the strain field of a material. In the NYR Laboratory, cylindrical samples of one inch of diameter have been traditionally studied. Nonetheless, there is a great motivation for doing systematic research on smaller and with different geometries samples; particularly sheets and samples for tensile tests. In such cases, a reduction of the spot size of the beam and an increase of its intensity would have a direct impact on minimizing measurement times. Hence, in the NYR Laboratory it has been considered the possibility of incorporating a neutron guide into the existent transmission line. According to all mentioned above, the main objective of this work consisted in the optimization of the flight transmission tube optics of neutrons. This optimization not only improved the existent line but also contributed to an election criterion for the neutron guide acquisition. The optimization was directed towards maximize the neutron flux on samples of mentioned geometries and to form the divergence of the incident beam upon them. It was then necessary to study the instrument neutron optics, i.e. the characteristics of the

  8. Synthesis, crystal structure refinement, and nonlinear-optical properties of CaB3O5(OH): Comparative crystal chemistry of calcium triborates

    International Nuclear Information System (INIS)

    Calcium triborate CaB3O5(OH) obtained by hydrothermal synthesis in the Ca(OH)2–H3BO3–Na2CO3–KCl system is studied by single-crystal X-ray diffraction. The parameters of the orthorhombic unit cell are as follows: a = 13.490(1), b = 6.9576(3), and c = 4.3930(2) Å; V = 412.32(3) Å3 and space group Pna21. The structure is refined in the anisotropic approximation of the atomic displacement parameters to R = 4.28% using 972 vertical bar F vertical bar > 4σ(F). It is confirmed that the crystal structure of Ca triborate CaB3O5(OH) is identical to that described earlier. The hydrogen atom is localized. An SHG signal stronger than that of the quartz standard is registered. The phase transition of calcium triborate into calciborite is found on heating. The comparative crystal-chemical analysis of a series of borates with the general chemical formula 2CaO · 3B2O3 · nH2O (n = 0–13) with the constant CaO: B2O3= 2: 3 ratio and variable content of water is performed

  9. CAB models for water: A new evaluation of the thermal neutron scattering laws for light and heavy water in ENDF-6 format

    International Nuclear Information System (INIS)

    Highlights: • We present a new evaluation of the thermal scattering laws for light and heavy water. • This evaluation is based on molecular and experimental data, with no free parameters. • Calculations with these libraries compare well with experimental values. • Libraries result in an improvement over existing ENDF scattering law files. - Abstract: In this work we present the CAB models for water: a set of new models for the evaluation of the thermal neutron scattering laws for light and heavy water in ENDF-6 format, using the LEAPR module of NJOY. These models are based on experimental structure data and frequency spectra computed from molecular dynamics simulations. The calculations show a significant improvement over ENDF/B-VI and ENDF/B-VII when compared with measurements of differential and integral scattering data

  10. Développement de liants basé sur CAB pour le moulage par injection de poudre (PIM) et le micro moulage l'injection de poudre (µ-PIM) de Zircon et Invar poudres

    OpenAIRE

    Hidalgo Garcia, Javier

    2014-01-01

    This PhD Thesis studied the use of binders based on cellulose acetate butyrate (CAB) andpoly(ethylene glycol) (PEG) in different type of materials, including a ceramic, the zirconiumsilicate, and a metallic alloy, the Invar 36. These materials share their low dimensionalstability with temperature with low coefficients of thermal expansion.The scope of this work is the study and comprehension of the behaviour of the mentionedbinder systems when they are employed in different PIM processes and ...

  11. 基于俯仰角加速度的驾驶室悬置系统修改%Modification of Cab Suspension System Based on Pitch Angular Acceleration

    Institute of Scientific and Technical Information of China (English)

    张军峰; 贺岩松; 杨海威; 黄勇

    2012-01-01

    A multi-body dynamics model based on flexible suspension cab was built. The excitation and validation signals were acquired through road-test. The accuracy of the model was investigated in three ways by degree of freedom, acceleration RMS and system mode shapes. Taking weighted pitch angular acceleration RMS as the evaluation target,the orthogonal test for matching parameters of the cab suspension was conducted in the frequency domain,the driver's seat weighted pitch angular acceleration RMS is reduced by 9% on average at various speeds, the weighted vertical acceleration RMS is reduced by 14% on average and reduction of the dynamic deflection of cab suspension is as 18%. Finally,the cab suspension springs were redesigned according to the calculation results.%采用柔性化的驾驶室建立驾驶室悬置系统的多体动力学模型,通过道路试验测得仿真模型的激励和验证信号,从自由度、加速度均方根值和系统模态等三个方面验证了模型的正确性.以俯仰角加权加速度均方根值为优化目标,在频域内对驾驶室悬置参数进行了正交试验匹配,使得不同车速下座椅处的俯仰角加权加速度均方根值平均降低14%,垂向加权加速度均方根值平均降低9%,驾驶室悬置动扰度平均降低18%.最后重新设计了驾驶室前后悬置弹簧.

  12. A Novel Two Domain-Fusion Protein in Cyanobacteria with Similarity to the CAB/ELIP/HLIP Superfamily: Evolutionary Implications and Regulation

    Institute of Scientific and Technical Information of China (English)

    Oliver Kilian; Anne Soisig Steunou; Arthur R.Grossman; Devaki Bhaya

    2008-01-01

    Vascular plants contain abundant, light-harvesting complexes in the thylakoid membrane that are non-covalently associated with chlorophylls and carotenoids. These light-harvesting chlorophyll a/b binding (LHC) proteins are members of an extended CAB/ELIP/HLIP superfamily of distantly related polypeptides, which have between one and four transmembrane helices (TMH). This superfamily includes the single TMH, high-light-inducible proteins (Hlips), found in cyanobacteria that are induced by various stress conditions, including high light, and are considered ancestral to the LHC proteins. The roles of, and evolutionary relationships between, these superfamily members are of particular interest,since they function in both light harvesting and photoprotection and may have evolved through tandem gene duplication and fusion events. We have investigated the Hlips (hli gene family) in the thermophilic unicellular cyanobacterium Synechococcus OS-B'. The five hli genes present on the genome of Synechococcus OS-B' are relatively similar, but transcript analyses indicate that there are different patterns of transcript accumulation when the cells are exposed to various growth conditions, suggesting that different Hlips may have specific functions. Hlip5 has an additional TMH at the N-terminus as a result of a novel fusion event. This additional TMH is very similar to a conserved hypothetical, single membrane-spanning polypeptide present in most cyanobacteria. The evolutionary significance of these results is discussed.

  13. Thermoluminescence studies of manganese doped calcium tetraborate (CaB4O7:Mn) nanocrystal synthesized by co-precipitation method

    International Nuclear Information System (INIS)

    Manganese (Mn) doped bone-equivalent calcium tetraborate (CaB4O7) nanocrystals were synthesized using co-precipitation and thermal treatment techniques. The synthesized nanophosphors are found to possess the monoclinic structure and have the particle size about 9 nm. They showed good luminescence quantum efficiency and enough potential for radiation dose measurement in medical and industrial purposes. The variation of dopant concentrations was investigated from 0.1 to 2 mol% and it was found that the optimal concentration of 1.4 mol% Mn has the highest sensitivity among other concentrations. The results revealed that Mn enhance the thermoluminescence (TL) sensitivity about 80 times higher than the un-doped samples at 1 kGy and the TL response over a wide range of doses from 0.05 Gy to 2.0 kGy increased linearly with increasing the absorbed dose. - Highlights: • The TL characterization of calcium tetraborate nanoparticles was reported for the first time. • The addition of manganese to host lattice can enhance the TL efficiency well. • The interesting feature of this study is a linearity of nanophosphor for wide range of doses. • The nanophosphor showed simple glow curve, good reproducibility and high sensitivity

  14. 空间与身份--论美籍韩裔作家佩蒂·金的《“可靠的”的士》%Space and Identity:On A Cab Called Reliable by Korean-American

    Institute of Scientific and Technical Information of China (English)

    洪雪花

    2015-01-01

    In Korean -American writer Patti Kim’s novel A Cab Called Reliable,the heroine,who is from a Korean immigrant family,narrates a tongue -tied story of identity dilemma confronted by new -generation Korean immigrants.The novel highlights the heroine’s perception of space and paradox in identity.After wit-nessing her mother leaving home,the heroine begins to pursue her self -identity through the seeking of the re-liable cab.This paper analyses Patti Kim’s A Cab Called Reliable by integrating space theory with identity theory and then probes into the connection between space and identity.%美籍韩裔作家佩蒂·金的小说《“可靠的”的士》中以移民美国的一个韩国家庭的故事展现了新一代美籍韩裔所面临的身份的尴尬处境。这部作品的主要特征在于主人公对空间的感知与矛盾的身份。作品讲述的是主人公在亲眼目睹了母亲出走后,借由对“可靠的”的士的寻找而开始的对自我身份的探求的心路历程。将空间理论和身份认同理论结合起来解读美籍韩裔作品《“可靠的”的士》,可以较好地探讨空间与身份的关系。

  15. 依据历史轨迹构建城市出租车移动概率模型%The moving probability model of urban cabs based on history trajectory

    Institute of Scientific and Technical Information of China (English)

    马武彬; 刘明星; 黄宏斌; 邓苏

    2014-01-01

    The model of urban cabs moving is one of the key issues for model building.The model needs reflecting moving state information of cabs.More importantly,users can quickly query the moving cabs.Under the condition of real time information of cabs which is hard to obtain,we should model the moving points and forecast the state information according to the moving history.A method which applies Hidden Markov theory to model of the moving trajectory is proposed.Through an analysis of real trajectory data of San Francisco,the caps moving model which is used to query the caps by users was constructed.Experiment with real datasets shows that the method proposed can simulate the moving state of caps.Users can also quickly obtain the useful location information from the model.%针对无法在线实时获取移动出租车实时状态信息的条件下,根据对历史轨迹信息的处理分析,提出将隐马尔科夫理论应用到城市出租车移动轨迹模型中,通过实际数据的分析建立出租车运动模型,通过对模型的计算来预测节点的位置分布概率,并在此模型上针对不同的用户需求进行查询处理,为用户提供搭车路线决策支持。通过利用真实数据集的实验证明,模型能够较好的模拟出出租车节点的运动状态,用户也能够从模型中获取较高精度的位置状态信息。

  16. Comportamiento asertivo y adaptación social : adaptación de una escala de comportamiento asertivo (CABS) para escolares de enseñanza primaria (6-12 años)

    OpenAIRE

    Peña, V. de la; Hernández Granda, Eva; Rodríguez Díaz, Francisco Javier

    2003-01-01

    Este trabajo es un estudio de la Escala de Comportamiento Asertivo (CABS) en una muestra de alumnos de Enseñanza Primaria de la Comunidad Autónoma del Principado de Asturias ( 2º Curso: N=119 y 4º y 6º: N=260). El objetivo es lograr una escala breve para discriminar el estilo asertivo frente a los no asertivos en las edades iniciales de escolarización. Para ello hemos eliminado los ítems redundantes (que producían una matriz de covarianzas con determinante 0) y, posteriormente, se ha evaluado...

  17. The mechanism for the nonlinear optical properties in La9Na3B8O27, La2Na3B3O9 and La2CaB10O19: ab initio studies

    International Nuclear Information System (INIS)

    The nonlinear optical (NLO) properties in La9Na3B8O27, La2Na3B3O9 and La2CaB10O19 are investigated using a plane-wave pseudopotential method. Based on the first-principles electronic band structures, the birefringence and second harmonic generation (SHG) coefficients for the three crystals are determined. The calculated values match well with the experimental results. In order to elucidate the microscopic origins of the NLO performances in these crystals, a real-space atom-cutting method is adopted to calculate the contribution from the respective ions and groups. It is revealed that the La cations have covalent interactions with the neighbor O ions so as to form the La–O groups. The La–O bond covalency, combined with the distortion of La–O groups, makes the large contribution to the overall SHG coefficients in addition to the B–O groups, as also intuitively demonstrated by a SHG-density analysis. (paper)

  18. Induction and Partial Characterization of CAB Fish Cell (Blastulae Embryonic Cell Line of Crucian Carp) Interferon%鲫鱼囊胚细胞干扰素的诱导及部分特性

    Institute of Scientific and Technical Information of China (English)

    张义兵; 王铁辉; 李戈强; 贾方钧; 俞小牧

    2000-01-01

    用紫外线灭活的草鱼呼肠孤病毒(GCRV)诱导鲫鱼囊胚细胞(CAB)能产生一种高滴度的抗病毒物质.这种物质在56℃及pH 2~11稳定;对胰蛋白酶敏感;抗病毒活性受被保护细胞的密度、培养温度及保护时间的影响;不能被GCRV的特异性抗体中和;无直接杀病毒作用;抗病毒机制依赖于细胞内RNA和蛋白质的合成;在多种鱼类培养细胞中具有抑制病毒作用.这些特性与哺乳类α/β干扰素一致,是一种鲫鱼干扰素.

  19. Análisis bibliométrico de la producción científica de México en ciencias agricolas a través de las bases de datos internacionales, "Agricola", "Agris", "Cab Abstracts", "Science Citation Index", "Social Science Citation Index" y "Tropag & Rural", en el periodo 1983-2002

    OpenAIRE

    Bravo Vinaja, Ángel

    2006-01-01

    En este trabajo de investigación se caracteriza la producción científica mexicana en el área de las Ciencias Agrícolas, utilizando para ello indicadores bibliométricos unidimensionales y multidimensionales de actividad científica, mediante los cuales se analiza por un lado la producción obtenida en las bases de datos: Agricola, Agris, Cab Abstracts, Tropag & Rural, Science Citation Index (SCI) y Social Science Citation Index (SSCI), y por el otro, la producción indexada solamente en las bases...

  20. Astrobiology with Robotic Telescopes at CAB

    OpenAIRE

    Jorge Navas; Antonio Pérez-Verde; Aurora Ullán; Luis Cuesta; M. Teresa Eibe

    2010-01-01

    The key objectives of RTRCAB are the identification of new exoplanets and especially the characterization of the known exoplanets by observing photometric and systematic monitoring of their transits. These telescopes, equipped with advanced technology, optimized control programs, and optical and technical characteristics adequate for this purpose, are ideal to make the observations that are required to carry out these programs. The achievement of these goals is ensured by the existence of thr...

  1. Astrobiology with Robotic Telescopes at CAB

    Directory of Open Access Journals (Sweden)

    Luis Cuesta

    2010-01-01

    Full Text Available The key objectives of RTRCAB are the identification of new exoplanets and especially the characterization of the known exoplanets by observing photometric and systematic monitoring of their transits. These telescopes, equipped with advanced technology, optimized control programs, and optical and technical characteristics adequate for this purpose, are ideal to make the observations that are required to carry out these programs. The achievement of these goals is ensured by the existence of three separated geographical stations. In this sense, there are several planned missions that have the same objectives among their scientific goals, like Kepler, CoRoT, GAIA, and PLATO.

  2. Barwood CNG Cab Fleet Study: Final Results

    Energy Technology Data Exchange (ETDEWEB)

    Whalen, P.; Kelly, K.; John, M.

    1999-05-03

    This report describes a fleet study conducted over a 12-month period to evaluate the operation of dedicated compress natural gas (CNG) Ford Crown Victoria sedans in a taxicab fleet. In the study, we assess the performance and reliability of the vehicles and the cost of operating the CNG vehicles compared to gasoline vehicles. The study results reveal that the CNG vehicles operated by this fleet offer both economic and environmental advantages. The total operating costs of the CNG vehicles were about 25% lower than those of the gasoline vehicles. The CNG vehicles performed as well as the gasoline vehicles, and were just as reliable. Barwood representatives and drivers have come to consider the CNG vehicles an asset to their business and to the air quality of the local community.

  3. Projeto de cabine de unidade mecânica de auxílio à colheita da cana-de-açúcar (unimac cana com base na ergonomia Cab design for a sugar cane harvesting machine based on ergonomics principles

    Directory of Open Access Journals (Sweden)

    Emanuel Antonio Barreto

    2013-05-01

    Full Text Available A mecanização da colheita da cana-de-açúcar parece ser o caminho para solução dos problemas decorrentes dos impactos ambientais das queimadas e do trabalho extremamente fatigante na colheita manual. Por outro lado, a mecanização total da colheita levaria milhares de trabalhadores ao desemprego. Para minimizar os impactos ambientais e manter parte desses empregos, a Agricef e a Unicamp estão desenvolvendo o projeto da unidade mecânica de auxílio à colheita da cana-de-açúcar (UNIMAC CANA, baseado em um conceito alternativo representado pela mecanização parcial da colheita, que está em fase de prototipagem. Particularmente, esta pesquisa teve como objetivo o dimensionamento da cabine desse dispositivo e o posicionamento de seus comandos e painéis, com base nas características antropométricas do operador brasileiro. Utilizou-se a metodologia projetual orientada pela preocupação com aspectos ergonômicos. As alternativas de projeto geradas através de quadros morfológicos culminaram no dimensionamento da cabine da máquina com sua disposição de comandos, painel e assento, de modo a acomodar o operador de forma segura e confortável. Através de simulação do campo visual do operador, concluiu-se que a cabine, adotando posição móvel em relação à maquina, seria uma opção viável de projeto nos atributos conforto e dirigibilidade.Sugar cane harvesting mechanization seems to be the solution for the problems related to the environment impact of sugar cane burning and to facilitate manual harvesting, which also is a extremely hard task. By the other way, full harvest mechanization would lead to a massive unemployment. To minimize environment impact and keep some of the harvesting jobs, Unicamp and Agricef are designing and building a harvesting machine that represents an alternative concept due to it partial harvesting mechanization. The main objective of this research is the design of the cab for this machine and the

  4. Signal Transduction Pathways that Regulate CAB Gene Expression

    Energy Technology Data Exchange (ETDEWEB)

    Chory, Joanne

    2006-01-16

    The process of chloroplast differentiation, involves the coordinate regulation of many nuclear and chloroplast genes. The cues for the initiation of this developmental program are both extrinsic (e.g., light) and intrinsic (cell-type and plastid signals). During this project period, we utilized a molecular genetic approach to select for Arabidopsis mutants that did not respond properly to environmental light conditions, as well as mutants that were unable to perceive plastid damage. These latter mutants, called gun mutants, define two retrograde signaling pathways that regulate nuclear gene expression in response to chloroplasts. A major finding was to identify a signal from chloroplasts that regulates nuclear gene transcription. This signal is the build-up of Mg-Protoporphyrin IX, a key intermediate of the chlorophyll biosynthetic pathway. The signaling pathways downstream of this signal are currently being studied. Completion of this project has provided an increased understanding of the input signals and retrograde signaling pathways that control nuclear gene expression in response to the functional state of chloroplasts. These studies should ultimately influence our abilities to manipulate plant growth and development, and will aid in the understanding of the developmental control of photosynthesis.

  5. Signal Transduction Pathways that Regulate CAB Gene Expression

    Energy Technology Data Exchange (ETDEWEB)

    Chory, Joanne

    2004-12-31

    The process of chloroplast differentiation, involves the coordinate regulation of many nuclear and chloroplast genes. The cues for the initiation of this developmental program are both extrinsic (e.g., light) and intrinsic (cell-type and plastid signals). During this project period, we utilized a molecular genetic approach to select for Arabidopsis mutants that did not respond properly to environmental light conditions, as well as mutants that were unable to perceive plastid damage. These latter mutants, called gun mutants, define two retrograde signaling pathways that regulate nuclear gene expression in response to chloroplasts. A major finding was to identify a signal from chloroplasts that regulates nuclear gene transcription. This signal is the build-up of Mg-Protoporphyrin IX, a key intermediate of the chlorophyll biosynthetic pathway. The signaling pathways downstream of this signal are currently being studied. Completion of this project has provided an increased understanding of the input signals and retrograde signaling pathways that control nuclear gene expression in response to the functional state of chloroplasts. These studies should ultimately influence our abilities to manipulate plant growth and development, and will aid in the understanding of the developmental control of photosynthesis.

  6. Optimized sub thermal neutron source to Linac of CAB

    International Nuclear Information System (INIS)

    We present the results of calculations performed with the code M C N P relative to the neutron field behavior within the moderator for the Bariloche-Linac cold neutron source, using polyethylene as pre moderator and solid mesitylene as moderating material at 90 K.The optimum dimensions for a moderator were obtained, with and without a pre moderator, from the point of view of neutron production and time-width of the neutron pulse.Finally, we adopted for our cold neutron source, a slab pre moderator of P L E at room temperature, and a cylindrical moderator of mesitylene at 90 K with a cooler system of stainless steel with windows of Zircaloy-4

  7. Taxi-cabs as Subjects for a Population Study

    Science.gov (United States)

    Bishop, J. A.; Bradley, J. S.

    1972-01-01

    Describes the use of capture-recapture techniques to estimate the population of taxis in Liverpool and demonstrates the points of similarity to animal population estimation. Considers advantages of studying taxis rather than organisms in introductory studies of the techniques. (AL)

  8. Slow Thinking and Deep Learning: Tversky and Kahneman's Taxi Cabs

    Science.gov (United States)

    Bedwell, Mike

    2015-01-01

    This article is based on classroom application of a problem story constructed by Amos Tversky in the 1970s. His intention was to evaluate human beings' intuitions about statistical inference. The problem was revisited by his colleague, the Nobel Prize winner Daniel Kahneman. The aim of this article is to show how popular science textbooks can…

  9. Post-perovskite transitions in CaB4+O3 at high pressure

    Science.gov (United States)

    Akaogi, M.; Shirako, Y.; Kojitani, H.; Takamori, S.; Yamaura, K.; Takayama-Muromachi, E.

    2010-03-01

    High-pressure phase transitions in CaRhO3 were examined using a multianvil apparatus up to 27 GPa and 1930 oC. CaRhO3 perovskite transforms to post-perovskite via a monoclinic intermediate phase with increasing pressure. Volume changes for the transitions of perovskite - intermediate phase and of intermediate phase - post-perovskite are -1.1 and -0.7 %, respectively. CaRhO3 post-perovskite is the fourth quenchable post-perovskite oxide found so far. By high-temperature calorimetric experiments, enthalpy of the perovskite - post-perovskite transition in CaRuO3 was measured as 15.2±3.3 kJ/mol. Combining the datum with those of CaIrO3, it is shown that CaIrO3 perovskite is energetically less stable than CaRuO3 perovskite. This is consistent with the fact that orthorhombic distortion of CaIrO3 perovskite is larger than CaRuO3, as indicated with the tilt-angle of octahedral framework of perovskite structure. The transition pressure from perovskite to post-perovskite in CaBO3 (B = Ru, Rh, Ir) increases almost linearly with decreasing the tilt-angle, suggesting that the perovskite - post-perovskite transition may result from instability of the perovskite structure with pressure.

  10. Development of a control system for automated cab roof deflectors for articulated trucks

    OpenAIRE

    Berkenbusch, Jan

    2015-01-01

    The adverse effects of emissions from the global transport industry on the environment have become increasingly apparent, with significant emphasis placed on their reduction through various initiatives. In the UK, Heavy Goods Vehicles (HGV’s) are used to transport 68 % of all goods. The majority of trucks are articulated (Truck and Trailer) – rather than rigid vehicles. Surveys show that within the UK in 2014, HGV’s travelled approximately 18,769 million kilometres (1). The CO2 emissions from...

  11. Greening London's black cabs: a study of driver's preferences for fuel cell taxis

    International Nuclear Information System (INIS)

    Road transport accounts for about a quarter of all carbon emissions in the UK, highlighting the need for low carbon alternatives to current fuels and vehicles. Running on hydrogen and virtually emissions-free, fuel cell vehicles are considered to be one of the most promising ways of reducing transport-related emissions. Understanding the user benefits of fuel cell vehicles and the determinants of demand is essential for their successful penetration. This contingent valuation study investigates the preferences of London taxi drivers for driving emissions-free hydrogen fuel cell taxis, both in the short term as part of a pilot project, and in the longer term if production line fuel cell taxis become available. The results show that willingness to pay to participate in a pilot project seems to be driven mostly by drivers' expectation of personal financial gains. In contrast, however, environmental considerations are found to affect taxi drivers' longer-term vehicle purchasing decisions. The results also reveal that driving hydrogen-fuelled vehicles does not seem to raise safety concerns amongst taxi drivers

  12. Design of a cold neutron source for 25MeV Linac of CAB (Centro Atomico Bariloche - Argentina)

    International Nuclear Information System (INIS)

    Cold neutrons are widely used in fields of research such as the dynamics of solids and liquids, the investigation of magnetic materials, material science, biology, and nuclear physics in general. Accelerator-based cold neutron sources have already proved to be well adapted to perform neutron scattering studies in all those fields.In this work we present the design of a cold neutron source in the electron Linac-based pulsed source at Centro Atomico Bariloche.The objective of this work is to develop an inexpensive yet efficient cold source with a simple moderator material.Although ideal materials for that purpose would be solid methane or liquid H2, due to economical and safety reasons light water ice, benzene or solid mesitylene were considered as cold moderators. In order to proceed with the design and optimization process of the neutron source, total cross sections for light water ice, benzene and mesitylene were measured at low temperature and thermal nuclear data libraries for such materials had to be developed.The purpose of these calculations was to optimize shape and size for the moderator at a working temperature.To calculations were performed using the MCNP-4C code and our libraries, together with files for (free-atom) carbon, hydrogen and oxygen at that temperature.The geometry studied consisted of a neutron source and different moderator (slab, cylindrical slab, grids, and sets premoderator - moderator with and without coupled).To simplify the system cooler, the slab geometry was changed to a coin shaped moderator using liquid nitrogen as cooler.From the variety of simulations performed, it was clear that a premoderator was necessary to obtain higher intensities.Furthermore, with a premoderator the thickness of the moderator was reduced, simplifying the cooling system.Finally, we adopted for our cold neutron source, a slab premoderator of PLE at room temperature, and a cylindrical moderator of mesitylene at 89K with a cooler system of stainless steel with windows of Zircaloy-4

  13. Main: LRENPCABE [PLACE

    Lifescience Database Archive (English)

    Full Text Available LRE NPCABE ... S000231 17-May-1998 (last modifie d) ke hi LRE ; A positive ... light re gulatory e le me nt in t ... obacco (N.p.) CAB (cab-E ) ge ne ; Locate d at -241; CAB; cab; cab-E ; CABE ; lig ... ht; le af; shoot; tobacco (Nicotiana plumbaginifolia) ACGT ...

  14. Ecosystem monitoring information collected in Hanna Shoal in the Chukchi Sea for the COMIDA CAB project from August 2012 to August 2013 (NODC Accession 0123220)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains physical, chemical, and biological data collected during research cruises for the Hanna Shoal Ecosystem Study. The study occurred at 138...

  15. In Vitro Activities of a Novel Cephalosporin, CB-181963 (CAB-175), against Methicillin-Susceptible or -Resistant Staphylococcus aureus and Glycopeptide-Intermediate Susceptible Staphylococci

    OpenAIRE

    Huang, Vanthida; Brown, William J.; Rybak, Michael J.

    2004-01-01

    We examined the activity of CB-181963, a novel cephalosporin, against methicillin-resistant Staphylococcus aureus (MRSA) (n = 200), methicillin-susceptible S. aureus (MSSA) (n = 50), glycopeptide-intermediate Staphylococcus species (GISS) (n = 47), and VRSA (n = 2) isolates. CB-181963 exhibited MIC profiles similar to those of linezolid against MRSA and GISS; however, activity against MSSA was similar to that of vancomycin. Time-kill study results of investigations of activity against MRSA, M...

  16. Development of binder systems based on CAB powder injection moulding (PIM) and micro powder injection moulding (μ-PIM) of zircon and invar powders

    OpenAIRE

    Hidalgo García, Javier

    2014-01-01

    Powder injection moulding (PIM), in its different versions, is a manufacturing method that in the last decades has been consolidated as an effective and competitive alternative to fabricate small size and complex geometry parts in large batches. Its future expansion to new applications and sectors requires an exhaustive research in new materials and the improvement of the manufacturing process itself. A better understanding between the variables materialprocessing- properties i...

  17. Thermoluminescent dosimetry properties of double doped calcium tetraborate (CaB4O7:Cu–Mn) nanophosphor exposed to gamma radiation

    International Nuclear Information System (INIS)

    Highlights: • TL properties of CaBT:Cu–Mn nanoparticles was reported for the first time. • The combined impurities of Cu and Mn ions could enhance the TL efficiency well. • Striking feature of this study is linearity dose response for a long span of exposures. • This nanophosphor showed simple glow curves, good re-usability and high sensitivity. -- Abstract: This study reports the dosimeteric properties of double Cu–Mn doped calcium tetraborate nanophosphor prepared by co-precipitation technique. The structure and the morphology of the synthesized nanocrystals were characterized by X-ray diffraction and transmission electron microscope. The presented XRD patterns showed the monoclinic structure and transmission electron microscopy revealed the formation of spherical shape nanoparticles with an average particle size of 8 nm. The results demonstrated that the synthesized calcium borate nanophosphor has the highest dosimetric sensitivity at combined concentration of 2% and 1%, copper and manganese molar ratio, respectively. TL glow curve of this material showed two well resolved peaks located at around 124 and 256 °C. The most striking dosimeteric feature of this nanomaterial is the linearity response, which has a long range of 0.05–3000 Gy for both temperature peaks

  18. Transportation-related barriers to care among African American women living with HIV/AIDS: “What you getting out of the cab for?”

    OpenAIRE

    Evans, Shenell D.; Williams, Bryman E.

    2013-01-01

    Transportation-related problems have been consistently reported as barriers to accessing and remaining in HIV medical care, particularly among African American women living in under-resourced areas. With emphasis on the Southern region of the United States, this commentary presents a brief overview of the HIV/AIDS epidemic among African Americans, barriers to remaining in HIV care, and pilot data from a study conducted among African American women living in Mississippi. A small focus group st...

  19. Transportation-related barriers to care among African American women living with HIV/AIDS: “What you getting out of the cab for?”

    Science.gov (United States)

    Evans, Shenell D.; Williams, Bryman E.

    2015-01-01

    Transportation-related problems have been consistently reported as barriers to accessing and remaining in HIV medical care, particularly among African American women living in under-resourced areas. With emphasis on the Southern region of the United States, this commentary presents a brief overview of the HIV/AIDS epidemic among African Americans, barriers to remaining in HIV care, and pilot data from a study conducted among African American women living in Mississippi. A small focus group study was conducted to examine the relative influence of transportation-related barriers on attendance and motivation to attend HIV medical care appointments. Eight African American women (mean age of 43.50, SD = 10.82) who were engaged in medical care participated in one focus group session. Time since diagnosis ranged from 6 to 17 years. Participants reported transportation-related barriers that were generally consistent with previous research, including lack of personal transportation, limited financial resources to pay family and friends for transportation or gasoline, and inconveniences associated with sharing van services with other patients. Participants appeared to have learned how to successfully navigate these barriers in order to remain in care. Interestingly, participants reported significant fear of disclosure related to use of transportation services provided by insurance providers and community organizations. Specifically, many of the women indicated that family, friends, and neighbors questioned them about where they were going and why they used taxis. These types of encounters might influence whether individuals utilize available transportation services. Participants provided several recommendations for improving the transportation system. Additional research is warranted to obtain a more representative sampling of opinions among African American women living in under-resourced areas. PMID:26523160

  20. Luminescence of Bi3+ in the orthorhombic perovskites CaB4+O3 (B4+=Zr, sn): Crossover from localized to D-state emission

    Science.gov (United States)

    Srivastava, Alok M.

    2016-08-01

    The optical properties of Bi3+ in the orthorhombic perovskites CaZrO3 and CaSnO3 are investigated. The Stokes shift of Bi3+ emission in CaZrO3 is small (∼0.80 eV) with the peak wavelength of the emission band occurring in the ultraviolet. This emission is attributed to the localized 3P0,1 → 1S0 optical transition. In contrast, the Stokes shift of the Bi3+ emission in CaSnO3 is large (>1 eV) with the emission band peaking in the visible. The emission band is also considerably broadened in CaSnO3. It is claimed that Bi3+ luminescence in CaSnO3 corresponds with the Bi3+ (6s2) -Sn4+ (5s°) charge transfer emission (D-state emission). The energy of the 1S0→3P1 (A-band) excitation band in both perovskites are very nearly the same. Physical reasoning is advanced for the occurrence and lack thereof of the D-state emission in these perovskites.

  1. Low frequency sound field control in rectangular listening rooms using CABS (Controlled Acoustic Bass System) will also reduce sound transmission to neighbor rooms

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2011-01-01

    Sound reproduction is often taking place in small and medium sized rectangular rooms. As rectangular rooms have 3 pairs of parallel walls the reflections at especially low frequencies will cause up to 30 dB spatial variations of the sound pressure level in the room. This will take place not only ...

  2. Ergonomic driver`s cab analysis at MAN, Munich: A comparative study with real and virtual persons; Ergonomische Fahrerplatzanalyse bei MAN: eine Vergleichsstudie mit realen und virtuellen Menschen

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, W. [MAN Nutzfahrzeuge AG, Muenchen (Germany); Koos, H. [MAN Nutzfahrzeuge AG, Muenchen (Germany); Lippmann, R. [IST GmbH, Kandern (Germany)

    1997-03-01

    At present, rational planning and development technologies are just as much in demand as rational production processes. In the continuous search for efficient development methods, ergonomy must also be taken into account. However, the extent to which ergonomic principles are applied depends to a high degree on persons who are called upon to contribute their expertise in this field creatively in product development in addition to their normal jobs. If the constructors and designers succeed in using tools with which ergonomic design principles can be implemented more quickly and reliably as the basis of their design process, this is then an important contribution to minimising development times and costs. After extensive research, the designer team decided to test the efficiency of an ergonomy tool in routine use on a project with limited time for which values for comparison are available from previous tests. A specific urgent task was a welcome opportunity for MAN AG to test a certain combined computer-aided ergonomy method in order to determine from the experience gained with it whether and how it may be applied in future and what the output of the application actually has to offer to the developers and the product. (orig.) [Deutsch] Rationelle Planungs- und Entwicklungstechnologien - die Ergonomie eingeschlossen - sind heute genauso gefragt wie rationelle Produktionsverfahren. Wenn es den Konstrukteuren und Designern gelingt, Werkzeuge einzusetzen, mit denen ergonomische Gestaltungsprinzpien als Grundlage ihres Entwurfsprozesses schneller und sicherer erarbeitet werden koennen, dann ist auch dies ein wichtiger Beitrag zur Minimierung der Entwicklungszeiten und -kosten. Deshalb entschied sich das Designerteam, die Effizienz eines Ergonomiewerkzeuges im Betriebsalltag an einem zeitlich begrenzten Projekt, fuer das Vergleichswerte aus zurueckliegenden Pruefungen mit anderen Methoden vorliegen, zu testen. Dabei sollte festgestellt werden, ob und wie es vielleicht zukuenftig eingesetzt werden kann und welchen Wert das Anwendungsergebnis ingesamt fuer die Entwickler und fuer das Produkt darstellt. (orig.)

  3. 2007年欧洲五款"最大型"驾驶室测评%Evaluating and testing of Europe five large-size cabs, 2007

    Institute of Scientific and Technical Information of China (English)

    吕明娟

    2007-01-01

    @@ 这是一次车型部件品质领域的较量.参赛对象有:德国的奔驰Axor和曼TGA LX驾驶室,瑞典的沃尔沃FM 400 Globetrotter驾驶室,法国的最新雷诺Premium Privilege驾驶室和荷兰的新款达夫CF85驾驶室(超大空间).

  4. Isolation, characterization and evolutionary relatedness of three members from the soybean multigene family encoding chlorophyll a/b binding proteins.

    OpenAIRE

    Walling, L L; Chang, Y.C.; Demmin, D S; Holzer, F M

    1988-01-01

    The soybean light-harvesting complex II (LHC II) was composed of one major and three minor chlorophyll a/b (Cab) binding proteins. This study demonstrated that the soybean genome contained at least 11 genes that code for these Cab proteins. Three members of the soybean Cab gene family were characterized. Cab 3 coded for a 25.7 kD mature apoprotein with a 32 amino acid transit peptide. Comparisons with previously published Cab protein sequences indicated that Cab 3 coded for the major Cab prot...

  5. Özel Sayı: Gül Sempozyumu

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2014-07-01

    Full Text Available Zentralblatt MATH, ChemicalAbstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, ChemicalAbstract, CAB Abstractand EBSCO Host indexes

  6. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-09-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  7. A Computational fluid dynamics model of viscous coupling of sensory hairs

    DEFF Research Database (Denmark)

    Lewin, Gregory C.; Hallam, John

    2010-01-01

    Abstracts in Anthropology, Academic OneFile, AGRICOLA, Biological Abstracts, BIOSIS, CAB Abstracts, CAB International, Chemical Abstracts Service (CAS), CSA, Current Abstracts, Current Contents/ Life Sciences, EBSCO, Elsevier Biobase, EMBASE, Gale, Global Health, Google Scholar, Health Reference...

  8. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-09-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  9. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-06-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  10. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-01-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  11. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-07-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  12. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2013-12-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  13. Özel Sayı: Biyomekanik

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-01-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  14. Özel Sayı: 7. Ulusal Lüminesans Dozimetri Kongresi

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2013-12-01

    Full Text Available Zentralblatt MATH, ChemicalAbstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, ChemicalAbstract, CAB Abstractand EBSCO Host indexes

  15. Özel Sayı: Geleceğin Mühendislik Eğitiminde Endüstri ile İşbirliği Sempozyumu

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-07-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  16. Primary production off Southern California relative to surface layer carbon budgets: A component of the California Basins Study, CaBS. Final report, [1 June 1989--14 November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Trees, C.C.

    1994-04-22

    This study started on 1 June 1989 and ended 14 November 1991. Two moored in situ natural fluorometers were deployed in January 1990 to collect bio-optical data for one year, making ground truth measurements around the mooring during 4 cruises. This one-year time series would investigate how the short-term physical forcing aliases the long-term primary production record such that the apparent, larger interannual variability in the record is in reality ``noise`` due to short-term fluctuations in the rate of nutrient input to the euphotic zone. These continuous measurements from moored bio-optical instruments would also allow better estimates of the mean and variance in primary production in these waters than has previously been available from shipboard measurements, as well as, phytoplankton response to short-term physical events. Ancillary measurements that were made were: (1) characterization of the apparent and inherent optical properties, (2) photosynthetic pigment distributions using both HPLC and standard fluorometric methods, (3) carbon, hydrogen and nitrogen content of suspended particulate matter, (4) primary production using conventional {sup 14}C methods from simulated in situ experiments.

  17. Functional assignments for the carboxyl-terminal domains of the ferrochelatase from Synechocystis PCC 6803: The CAB domain plays a regulatory role, and region II is essential for catalysis

    Czech Academy of Sciences Publication Activity Database

    Sobotka, Roman; Tichý, Martin; Wilde, A.; Hunter, C. N.

    2011-01-01

    Roč. 155, č. 4 (2011), 1735-1747. ISSN 0032-0889 R&D Projects: GA ČR GAP501/10/1000 Institutional research plan: CEZ:AV0Z50200510 Keywords : TRANSFER-RNA REDUCTASE * DELTA-AMINOLEVULINIC-ACID * PHOTOSYSTEM-II Subject RIV: EE - Microbiology, Virology Impact factor: 6.535, year: 2011

  18. 拖拉机驾驶室悬架油气弹簧设计与试验%Design and Experiment of Hydro-pneumatic Spring of Tractor Cab Suspension

    Institute of Scientific and Technical Information of China (English)

    朱思洪; 李科; 李朝全; 吕宝占; 徐刚

    2014-01-01

    基于CF700型拖拉机驾驶室悬架参数要求和流体力学理论建立了一种油气弹簧的弹性力及阻尼力模型.计算了油气弹簧关键参数,设计了阻尼可调的油气弹簧.试验研究了激励、节流阀开度及单向阀开度对油气弹簧输出力的影响.试验结果表明,所研制的油气弹簧有较大的阻尼力调节范围,节流阀开度同时对油气弹簧压缩与复原行程输出力有影响,单向阀开度只对压缩行程输出力有影响,节流阀开度对输出力影响较单向阀明显.试验验证了设计思路和方法的有效性,为拖拉机驾驶室油气悬架减振性能的研究奠定了基础.

  19. Chemical and benthos data collected from CTD, bottle, and other instruments in the Chukchi Sea in 2009-2010 as part of the Chukchi Sea Offshore Monitoring in Drilling Area - (Chemical and Benthos) (COMIDA-CAB) project (NODC Accession 0095566)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains physical, chemical, and biological data collected during research cruises for the Chukchi Sea Offshore Monitoring in Drilling Area (Chemical...

  20. 77 FR 21311 - Locomotive Safety Standards

    Science.gov (United States)

    2012-04-09

    ..., locomotive cab securement, equipping new and remanufactured locomotive cabs with air conditioning units, and... equipping new locomotives with air conditioning units inside the locomotive cab and maintaining those units... all air brake filtering devices to be changed annually and the air ] compressor to be overhauled...

  1. NCBI nr-aa BLAST: CBRC-PHAM-01-1625 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-PHAM-01-1625 emb|CAB42602.1| hyperpolarization-activated cation channel HCN2 [...Homo sapiens] emb|CAB42630.1| hyperpolarization-activated cyclic nucleotide-gated channel hHCN2 [Homo sapiens] CAB42602.1 8e-05 34% ...

  2. NCBI nr-aa BLAST: CBRC-PTRO-16-0005 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-PTRO-16-0005 emb|CAB42602.1| hyperpolarization-activated cation channel HCN2 [...Homo sapiens] emb|CAB42630.1| hyperpolarization-activated cyclic nucleotide-gated channel hHCN2 [Homo sapiens] CAB42602.1 0.0 94% ...

  3. Time based room correction system for low frequencies using multiple loudspeakers

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2007-01-01

    -domain by the construction of a finite-difference time-domain approximation program (FDTD) has lead to a novel and simple solution also working in the time-domain called Controlled Acoustically Bass System (CABS). Working in the time-domain CABS includes additional cancelling loudspeakers at the back wall...... and software has been made from scratch for further development of CABS....

  4. NCBI nr-aa BLAST: CBRC-HSAP-15-0018 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-HSAP-15-0018 emb|CAB42602.1| hyperpolarization-activated cation channel HCN2 [...Homo sapiens] emb|CAB42630.1| hyperpolarization-activated cyclic nucleotide-gated channel hHCN2 [Homo sapiens] CAB42602.1 0.0 94% ...

  5. NCBI nr-aa BLAST: CBRC-RMAC-14-0006 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-RMAC-14-0006 emb|CAB42602.1| hyperpolarization-activated cation channel HCN2 [...Homo sapiens] emb|CAB42630.1| hyperpolarization-activated cyclic nucleotide-gated channel hHCN2 [Homo sapiens] CAB42602.1 6e-05 34% ...

  6. Profiling antibody responses to infections by Chlamydia abortus enables identification of potential virulence factors and candidates for serodiagnosis.

    Directory of Open Access Journals (Sweden)

    Vera Forsbach-Birk

    Full Text Available Enzootic abortion of ewes (EAE due to infection with the obligate intracellular pathogen Chlamydia (C. abortus is an important zoonosis leading to considerable economic loss to agriculture worldwide. The pathogen can be transmitted to humans and may lead to serious infection in pregnant women. Knowledge about epidemiology, clinical course and transmission to humans is hampered by the lack of reliable diagnostic tools. Immunoreactive proteins, which are expressed in infected animals and humans, may serve as novel candidates for diagnostic marker proteins and represent putative virulence factors. In order to broaden the spectrum of immunogenic C. abortus proteins we applied 2D immunoblot analysis and screening of an expression library using human and animal sera. We have identified 48 immunoreactive proteins representing potential diagnostic markers and also putative virulence factors, such as CAB080 (homologue of the "macrophage infectivity potentiator", MIP, CAB167 (homologue of the "translocated actin recruitment protein", TARP, CAB712 (homologue of the "chlamydial protease-like activity factor", CPAF, CAB776 (homologue of the "Polymorphic membrane protein D", PmpD, and the "hypothetical proteins" CAB063, CAB408 and CAB821, which are predicted to be type III secreted. We selected two putative virulence factors for further characterization, i.e. CAB080 (cMIP and CAB063, and studied their expression profiles at transcript and protein levels. Analysis of the subcellular localization of both proteins throughout the developmental cycle revealed CAB063 being the first C. abortus protein shown to be translocated to the host cell nucleus.

  7. Spectrophotometric analysis of Cabergoline in pharmaceutical preparations

    OpenAIRE

    Salman, Demet; Dogan, Aysegul; Basci, Nursabah E.

    2011-01-01

    Cabergoline (CAB) is a synthetic ergoline dopamine agonist with high affinity to D2 receptors, thus used for the treatment of Parkinson's patients and hyperprolactinemia disorders. In this study, simple, fast, reliable and validated UV-VIS and 2nd order derivative spectrophotometric methods for determination of CAB in pharmaceutical preparations were developed without any previous sample preparation step. Determination of CAB was performed at 280 nm wavelength by UV-VIS spectrophotometry and ...

  8. 41 CFR 101-26.501-2 - Standardized buying programs.

    Science.gov (United States)

    2010-07-01

    ... and 6×4 cab-chassis, stake, van, dump, and truck-tractor; 19,000 to 60,000 pounds GVWR. (ii) 4×4 and 6×4 cab-chassis, stake, dump, and truck-tractor; 26,000 to 52,000 pounds GVWR. (iii) 1,200 and 2,000... Federal Specification No. KKK-A-1822): Type I, modular body on cab-chassis; Type II, van body with...

  9. Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline.

    Science.gov (United States)

    Lin, Shao Jian; Leng, Zhi Gen; Guo, Yu Hang; Cai, Lin; Cai, Yu; Li, Ning; Shang, Han Bing; Le, Wei-Dong; Zhao, Wei Guo; Wu, Zhe Bao

    2015-11-17

    Cabergoline (CAB), the first-line drug for treatment of prolactinomas, is effective in suppressing prolactin hypersecretion, reducing tumor size, and restoring gonadal function. However, mechanisms for CAB-mediated tumor shrinkage are largely unknown. Here we report a novel cytotoxic mechanism for CAB. CAB induced formation of autophagosome in rat pituitary tumor MMQ and GH3 cells at the early stage through inhibiting mTOR pathway, resulting in higher conversion rates of LC3-I to LC3-II, GFP-LC3 aggregation, and increased autophagosome formation. Interestingly, CAB treatment augmented lysosome acidification and resulted in impaired proteolytic degradation within autolysosomes. This blocked the autophagic flux, leading to the accumulation of p62 aggregation and undigested autolysosomes. Knockdown of ATG7, ATG5, or Becn1, could significantly rescue the CAB-mediated cell death of MMQ cells (p < 0.05). CAB-induced autophagy and blockade of autophagy flux participated in antitumoral action in vivo. In conclusion, our study provides evidence that CAB concomitantly induces autophagy and inhibits the autophagic flux, leading to autophagy-dependent cell death. These findings elucidate novel mechanisms for CAB action. PMID:26513171

  10. Role of Salmonella enterica Serovar Typhimurium Two-Component System PreA/PreB in Modulating PmrA-Regulated Gene Transcription

    OpenAIRE

    Merighi, Massimo; Carroll-Portillo, Amanda; Septer, Alecia N.; Bhatiya, Aditi; Gunn, John S.

    2006-01-01

    The PmrA/PmrB two-component system encoded by the pmrCAB operon regulates the modification of Salmonella enterica serovar Typhimurium lipopolysaccharide leading to polymyxin B resistance. PmrA and PhoP are the only known activators of pmrCAB. A transposon mutagenesis screen for additional regulators of a pmrC::MudJ fusion led to the identification of a two-component system, termed PreA/PreB (pmrCAB regulators A and B), that controls the transcription of the pmrCAB operon in response to unknow...

  11. Role of Salmonella enterica serovar Typhimurium two-component system PreA/PreB in modulating PmrA-regulated gene transcription.

    Science.gov (United States)

    Merighi, Massimo; Carroll-Portillo, Amanda; Septer, Alecia N; Bhatiya, Aditi; Gunn, John S

    2006-01-01

    The PmrA/PmrB two-component system encoded by the pmrCAB operon regulates the modification of Salmonella enterica serovar Typhimurium lipopolysaccharide leading to polymyxin B resistance. PmrA and PhoP are the only known activators of pmrCAB. A transposon mutagenesis screen for additional regulators of a pmrC::MudJ fusion led to the identification of a two-component system, termed PreA/PreB (pmrCAB regulators A and B), that controls the transcription of the pmrCAB operon in response to unknown signals. The initial observations indicated that insertions in, or a deletion of, the preB sensor, but not the preA response regulator, caused upregulation of pmrCAB. Interestingly, the expression of pmrCAB was not upregulated in a preAB mutant grown in LB broth, implicating PreA in the increased expression of pmrCAB in the preB strain. This was confirmed by overexpression of preA(+) in preAB or preB backgrounds, which resulted in significant upregulation or further upregulation of pmrCAB. No such effect was observed in any tested preB(+) backgrounds. Additionally, an ectopic construct expressing a preA[D51A] allele also failed to upregulate pmrC in any of the pre backgrounds tested, which implies that there is a need for phosphorylation in the activation of the target genes. The observed upregulation of pmrCAB occurred independently of the response regulators PmrA and PhoP. Although a preB mutation led to increased transcription of pmrCAB, this did not result in a measurable effect on polymyxin B resistance. Our genetic data support a model of regulation whereby, in response to unknown signals, the PreB sensor activates PreA, which in turn indirectly upregulates pmrCAB transcription. PMID:16352830

  12. NCBI nr-aa BLAST: CBRC-CBRE-01-0958 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRE-01-0958 ref|NP_496808.1| F15D4.7 [Caenorhabditis elegans] emb|CAB02490.2|... Hypothetical protein F15D4.7 [Caenorhabditis elegans] emb|CAB60425.1| Hypothetical protein F15D4.7 [Caenorhabditis elegans] NP_496808.1 0.0 38% ...

  13. NCBI nr-aa BLAST: CBRC-CBRI-05-0314 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRI-05-0314 ref|NP_506256.2| F15B9.7 [Caenorhabditis elegans] emb|CAB01449.2|... Hypothetical protein F15B9.7 [Caenorhabditis elegans] emb|CAB01427.2| Hypothetical protein F15B9.7 [Caenorhabditis elegans] NP_506256.2 0.0 84% ...

  14. NCBI nr-aa BLAST: CBRC-CELE-05-0524 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CELE-05-0524 ref|NP_506256.2| F15B9.7 [Caenorhabditis elegans] emb|CAB01449.2|... Hypothetical protein F15B9.7 [Caenorhabditis elegans] emb|CAB01427.2| Hypothetical protein F15B9.7 [Caenorhabditis elegans] NP_506256.2 0.0 95% ...

  15. NCBI nr-aa BLAST: CBRC-CBRE-01-0069 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRE-01-0069 ref|NP_496808.1| F15D4.7 [Caenorhabditis elegans] emb|CAB02490.2|... Hypothetical protein F15D4.7 [Caenorhabditis elegans] emb|CAB60425.1| Hypothetical protein F15D4.7 [Caenorhabditis elegans] NP_496808.1 0.0 34% ...

  16. NCBI nr-aa BLAST: CBRC-CELE-05-0706 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CELE-05-0706 ref|NP_507019.1| C06C6.1 [Caenorhabditis elegans] emb|CAB07561.1|... Hypothetical protein C06C6.1 [Caenorhabditis elegans] emb|CAB07667.1| Hypothetical protein C06C6.1 [Caenorhabditis elegans] NP_507019.1 0.0 94% ...

  17. NCBI nr-aa BLAST: CBRC-CREM-01-1025 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CREM-01-1025 ref|NP_496808.1| F15D4.7 [Caenorhabditis elegans] emb|CAB02490.2|... Hypothetical protein F15D4.7 [Caenorhabditis elegans] emb|CAB60425.1| Hypothetical protein F15D4.7 [Caenorhabditis elegans] NP_496808.1 0.0 33% ...

  18. Sensitivity of Ground-Based Remote Sensing Estimates of Wheat Chlorophyll Content to Variation in Soil Reflectance

    Science.gov (United States)

    Most ground-based optical sensors utilize spectral indices (SI) to estimate wheat (Triticum aestivum L.) chlorophyll a and b content (Cab) critical for advising in-season nitrogen fertilizer needs. These indices are sensitive to Cab, leaf area index (LAI), and soil background variation, but relative...

  19. Country analysis briefs: 1994. Profiles of major world energy producers, consumers, and transport centers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    Country Analysis Briefs: 1994 is a compilation of country profiles prepared by the Energy Markets and Contingency Information Division (EMCID) of the Office of Energy Markets and End Use. EMCID maintains Country Analysis Briefs (CABs) for specific countries or geographical areas that are important to world energy markets. As a general rule, CABs are prepared for all members of the Organization of Petroleum Exporting Countries (OPEC), major non-OPEC oil producers (i.e., the North Sea, Russia), major energy transit areas (i.e., Ukraine), and other areas of current interest to energy analysts and policy makers. As of January 1995, EMCID maintained over 40 CABs, updated on an annual schedule and subject to revision as events warrant. This report includes 25 CABs updated during 1994. All CABs contain a profile section, a map showing the country`s location, and a narrative section. The profile section includes outlines of the country`s economy, energy sector, and environment. The narrative provides further information and discussion of these topics. Some CABs also include a detailed map displaying locations of major oil and gas fields, pipelines, ports, etc. These maps were created as a result of special individual requests and so are not typically a standard feature of the CABs. They are presented here wherever available as a supplement to the information contained in the CABs.

  20. 49 CFR 238.405 - Longitudinal static compressive strength.

    Science.gov (United States)

    2010-10-01

    ... crash refuge for crewmembers occupying the cab of a power car, the underframe of the cab of a power car... volumes of a power car or a trailer car designed to crush as part of the crash energy management design...) The underframe of the occupied volume of each trailer car shall resist a minimum longitudinal...

  1. Early Identification of High-Ability Students: Clinical Assessment of Behavior

    Science.gov (United States)

    Bracken, Bruce A.; Brown, Elissa F.

    2008-01-01

    This study investigated the ability of teachers to accurately rate the cognitive and academic functioning of 1,375 students in kindergarten through the third grade on the Clinical Assessment of Behavior (CAB), as compared to two objective cognitive ability tests. CAB teacher ratings were compared for high-ability students who were currently…

  2. Controlled and high throughput fabrication of poly(trimethylene terphthalate) nanofibers via melt extrusion of immiscible blends

    Science.gov (United States)

    Immiscible blends of cellulose acetate butyrate (CAB) and poly(trimethylene terephthalate) (PTT) were melt extruded through a two strand rod die. The extrudates were hot-drawn at the die exit at different draw ratios. PTT fibers were obtained by removal of the CAB matrix from the drawn extrudates, a...

  3. Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam.

    Science.gov (United States)

    Reese, Melinda J; Bowers, Gary D; Humphreys, Joan E; Gould, Elizabeth P; Ford, Susan L; Webster, Lindsey O; Polli, Joseph W

    2016-01-01

    1. Cabotegravir (CAB; GSK1265744) is a potent HIV integrase inhibitor in clinical development as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. 2. This work investigated if CAB was a substrate for efflux transporters, the potential for CAB to interact with drug-metabolizing enzymes and transporters to cause clinical drug interactions, and the effect of CAB on the pharmacokinetics of midazolam, a CYP3A4 probe substrate, in humans. 3. CAB is a substrate for Pgp and BCRP; however, its high intrinsic membrane permeability limits the impact of these transporters on its intestinal absorption. 4. At clinically relevant concentrations, CAB did not inhibit or induce any of the CYP or UGT enzymes evaluated in vitro and had no effect on the clinical pharmacokinetics of midazolam. 5. CAB is an inhibitor of OAT1 (IC50 0.81 µM) and OAT3 (IC50 0.41 µM) but did not or only weakly inhibited Pgp, BCRP, MRP2, MRP4, MATE1, MATE2-K, OATP1B1, OATP1B3, OCT1, OCT2 or BSEP. 6. Based on regulatory guidelines and quantitative extrapolations, CAB has a low propensity to cause clinically significant drug interactions, except for coadministration with OAT1 or OAT3 substrates. PMID:26340566

  4. De invloed van kortere remtijden op de verkeersveiligheid : beschouwingen over een gecombineerd gas- en rempedaal.

    NARCIS (Netherlands)

    Kampen, L.T.B. van & Schoon, C.C.

    1991-01-01

    A combined accelerator-brake pedal in passenger cars is a device that combines the accelerating and braking functions in one pedal. This device is known as the CAB system. The aim of the CAB system is to save the time that is normally spent in moving the foot from the accelerator to the brake pedal.

  5. 49 CFR 236.588 - Periodic test.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Periodic test. 236.588 Section 236.588..., Train Control and Cab Signal Systems Inspection and Tests; Locomotive § 236.588 Periodic test. Except as provided in § 236.586, periodic test of the automatic train stop, train control, or cab signal...

  6. Gene : CBRC-ATHA-05-0021 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-ATHA-05-0021 Novel 5 D UNKNOWN POLX_TOBAC 5e-44 28% emb|CAB10225.1| retrovirus -related like ... polyprotein [Arabidopsis thaliana] emb|CAB78488.1| retrovirus -related like polyprotein [Arabidopsis thaliana] 1e ...

  7. NCBI nr-aa BLAST: CBRC-RMAC-18-0006 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-RMAC-18-0006 emb|CAB91059.1| NADH dehydrogenase subunit 4 [Drosophila melanogas...ter] gb|AAF77234.1| NADH dehydrogenase subunit 4 [Drosophila melanogaster] gb|AAF77246.1| NADH dehydrogenase subunit 4 [Drosophila melanogaster] CAB91059.1 0.16 26% ...

  8. ALP conversion and the soft X-ray excess in the outskirts of the Coma cluster

    International Nuclear Information System (INIS)

    It was recently found that the soft X-ray excess in the center of the Coma cluster can be fitted by conversion of axion-like-particles (ALPs) of a cosmic axion background (CAB) to photons. We extend this analysis to the outskirts of Coma, including regions up to 5 Mpc from the center of the cluster. We extract the excess soft X-ray flux from ROSAT All-Sky Survey data and compare it to the expected flux from ALP to photon conversion of a CAB. The soft X-ray excess both in the center and the outskirts of Coma can be simultaneously fitted by ALP to photon conversion of a CAB. Given the uncertainties of the cluster magnetic field in the outskirts we constrain the parameter space of the CAB. In particular, an upper limit on the CAB mean energy and a range of allowed ALP-photon couplings are derived

  9. ALP conversion and the soft X-ray excess in the outskirts of the Coma cluster

    Energy Technology Data Exchange (ETDEWEB)

    Kraljic, David; Rummel, Markus; Conlon, Joseph P., E-mail: David.Kraljic@physics.ox.ac.uk, E-mail: Markus.Rummel@physics.ox.ac.uk, E-mail: j.conlon1@physics.ox.ac.uk [Rudolf Peierls Centre for Theoretical Physics, University of Oxford, 1 Keble Road, Oxford, OX1 3NP (United Kingdom)

    2015-01-01

    It was recently found that the soft X-ray excess in the center of the Coma cluster can be fitted by conversion of axion-like-particles (ALPs) of a cosmic axion background (CAB) to photons. We extend this analysis to the outskirts of Coma, including regions up to 5 Mpc from the center of the cluster. We extract the excess soft X-ray flux from ROSAT All-Sky Survey data and compare it to the expected flux from ALP to photon conversion of a CAB. The soft X-ray excess both in the center and the outskirts of Coma can be simultaneously fitted by ALP to photon conversion of a CAB. Given the uncertainties of the cluster magnetic field in the outskirts we constrain the parameter space of the CAB. In particular, an upper limit on the CAB mean energy and a range of allowed ALP-photon couplings are derived.

  10. 竹炭有机肥对有机卷心菜叶绿素荧光特性和相对叶绿素含量的影响%Effect of bamboo charcoal organic fertilizer on chlorophyll fluores-cence characteristics and relative chlorophyll content of organic cab-bage

    Institute of Scientific and Technical Information of China (English)

    马锦丽; 黄鹤凤; 江洪; 舒海燕; 张金梦; 吴丹娜; 孙文文; 吴孟霖; 方成圆; 陈晓峰

    2015-01-01

    Selecting organic cabbage in Chongming of Shanghai dol y farm as the research object, and set up three bamboo charcoal organic fertilizer processing:BC180 (180 kg/20 m × 20 m), BC60 (60 kg/20 m × 20 m), CK (control), During July(Rosette period) and August(Fruit period) in 2014, its chlorophyl fluorescence kinetics parameter and relative chlorophyl content is determined by a random and relative method, in order to analyze the influence of bamboo charcoal organic fertilizer on the organic cabbage.The results showed that different growth period under the same processing, organic cabbage leaf blade light systemⅡ(PSⅡ), initial fluorescence (F0), the largest fluorescence (Fm), maximum photochemical efficiency (Fv/Fm), potential photosynthetic activity (Fv/F0), the actual photochemical efficiency (Yield) were rosette period > fruit period; Apparent photosynthetic electron transport rate (ETR), coefficient of photochemical quenching (qP) and relative chlorophyl content (SPAD) was fruit period>rosette period. The same growth period under different processing, Fv/Fm, Fv/F0, Yield, ETR, qP were increasing as fertilizer rate increasing, NPQ increases during rosette period, and became lower during knot bal period. Different growth period and fertilizer's interaction on Fm, Fv/Fm, Fv/F0, NPQ were very significant (P结球期;表观光合电子传递速率(ETR)、光化学淬灭系数(qP)、相对叶绿素含量(SPAD)为结球期>莲座期。同一生长期不同处理下,Fv/Fm、Fv/F0、Yield、ETR、qP均是随着施肥量增加而增加,NPQ则为莲座期增加,结球期又降低。不同生长期不同施肥量交互作用对Fm、Fv/Fm、Fv/F0、NPQ影响极显著(P<0.01),对qP影响显著(P<0.05)。这说明增施竹炭有机肥对有机卷心菜叶绿素荧光指标和相对叶绿素含量有显著影响,且BC60处理下更有助于其光合固碳,增加产量,符合低碳有机农业宗旨。

  11. Second attempt of Cabergoline withdrawal in patients with prolactinomas after a failed first attempt : is it worthwhile?

    Directory of Open Access Journals (Sweden)

    Lucio eVilar

    2015-02-01

    Full Text Available Successful discontinuation of cabergoline (CAB treatment has been reported in 31 to 74% of prolactinomas patients treated for at least two years. In contrast, it is not well established whether CAB therapy can be successfully withdrawn after a failed first attempt. This prospective open trial was designed to address this topic and to try to identify possible predictor factors.Among 180 patients with prolactinomas on CAB therapy, the authors selected those who fulfilled very strict criteria, particularly additional CAB therapy for at least 2 years, normalization of serum prolactin (PRL levels following CAB restart, no tumor remnant > 10 mm, no previous pituitary radiotherapy or surgery; and current CAB dose ≤1.0 mg/week. Recurrence was defined as an increase of PRL levels above the upper limit of normal.A total of 34 patients (70.6% female treated with CAB for 24-30 months were recruited. Ten patients (29.4 % remained without evidence of recurrence after 24–26 months of follow-up. Twenty-four patients (70.6% recurred within 15 months (75% within 12 months after drug withdrawal and ~80% were restarted CAB. Median time to recurrence was 10.5 months (range, 3–15. Despite overlapping values, non-recurring patients had significantly lower mean PRL levels before withdrawal. Moreover, the recurrence rate was lower in subjects without visible tumor on pituitary MRI than in those with small remnant tumor (60 vs. 79%, though the difference was not statistically significant (P= 0.20. No other characteristic could be identified as a predictor of successful CAB discontinuation.In conclusion, a second attempt of CAB withdrawal after 2 additional years of therapy may be successful, particularly in patients with lower PRL levels and no visible tumor on pituitary MRI. Close monitoring of PRL level is mandatory, especially within the first year after withdrawal, where most recurrences are detected.

  12. Protonated form: the potent form of potassium-competitive acid blockers.

    Directory of Open Access Journals (Sweden)

    Hua-Jun Luo

    Full Text Available Potassium-competitive acid blockers (P-CABs are highly safe and active drugs targeting H+,K+-ATPase to cure acid-related gastric diseases. In this study, we for the first time investigate the interaction mechanism between the protonated form of P-CABs and human H+,K+-ATPase using homology modeling, molecular docking, molecular dynamics and binding free energy calculation methods. The results explain why P-CABs have higher activities with higher pKa values or at lower pH. With positive charge, the protonated forms of P-CABs have more competitive advantage to block potassium ion into luminal channel and to bind with H+,K+-ATPase via electrostatic interactions. The binding affinity of the protonated form is more favorable than that of the neutral P-CABs. In particular, Asp139 should be a very important binding site for the protonated form of P-CABs through hydrogen bonds and electrostatic interactions. These findings could promote the rational design of novel P-CABs.

  13. Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme

    OpenAIRE

    WU, Jing; Bu, Weishu; Sheppard, Kelly; Kitabatake, Makoto; Kwon, Suk-Tae; Söll, Dieter; Smith, Janet L.

    2009-01-01

    Many bacteria form Gln-tRNAGln and Asn-tRNAAsn by conversion of the misacylated Glu-tRNAGln and Asp-tRNAAsn species catalyzed by the GatCAB amidotransferase in the presence of ATP and an amide donor (glutamine or asparagine). Here we report the crystal structures of GatCAB from the hyperthermophilic bacterium Aquifex aeolicus complexed with glutamine, asparagine, aspartate, ADP, or ATP. In contrast to the Staphylococcus aureus GatCAB, the A. aeolicus enzyme formed acyl-enzyme intermediates wi...

  14. Neutron inelastic scattering from fumed silica

    International Nuclear Information System (INIS)

    Neutron inelastic scattering measurement have been performed on samples of fumed silica ('Cab-O-Sil') as a function of energy, momentum-transfer vector Q, and temperature T, and compared with analogous results for amorphous quartz. No evidence seen for a sharp crossover in the vibrational density of states of Cab-O-Sil between phonon and fracton regimes, but the inelastic scattering shows anomalous behavior in several respects. Neither the T dependence nor the Q dependence nor the absolute intensity of the scattering from Cab-O-Sil is in accord with simple phonon models. (author)

  15. Structural dynamics modeling and testing of the Department of Energy tractor/trailer combination

    Energy Technology Data Exchange (ETDEWEB)

    Field, R.V. Jr.; Hurtado, J.E.; Carne, T.G.; Dohrmann, C.R.

    1996-12-31

    This study presents a combined analytical and experimental effort to characterize and improve the ride quality of the Department of Energy tractor/trailer combination. The focus is to augment the experimental test results with the use of a high quality computer model. The discussion includes an overview of the finite element model of the vehicle and experimental modal test results. System identification techniques are employed to update the mathematical model. The validated model is then used to illustrate the benefits of incorporating two major design changes, namely the switch from a separate cab/sleeper configuration to an integrated cab, and the use of a cab suspension system.

  16. Manejo Integral de Agua y Suelo en Centroamérica. Bases científicas para el desarrollo rural comunitario.

    OpenAIRE

    Algeet Abarquero, Nur; Fernández Moya, Jesús; Lianes Revilla, Elena; Marchamalo Sacristán, Miguel; Martínez Marín, Rubén; Rejas, Juan Gregorio; Alvarado, Alfredo; Abreu, A; Perez, Alexandra; Irias, Alicia; Sanchez, Alexis; Avarela, A.; Aguirre, Carmen; Cruz, Mirna; Moreno, Eduardo

    2012-01-01

    Este libro recoge los frutos de la colaboración y trabajo conjunto de un grupo de Universidades Iberoamericanas entre 2007 y 2012 el marco de las actividades del Programa de Cooperación Comunidad, Agua y Bosque en Centroamérica (CAB Centroamérica, http://www2.caminos.upm.es/Departamentos/imt/Topografia/Cab/cab.html ). Las actividades se han realizado con el apoyo del Programa de Cooperación Universitaria PCI-AECID IBEROAMÉRICA, de la Dirección de Cooperación para el Desarrollo de la Universid...

  17. Alcohol Energy Drinks

    Science.gov (United States)

    ... Home / About Addiction / Alcohol / Alcohol Energy Drinks Alcohol Energy Drinks Read 17728 times font size decrease font size increase font size Print Email Alcohol energy drinks (AEDs) or Caffeinated alcoholic beverages (CABs) are ...

  18. Serious Concerns Over Alcoholic Beverages with Added Caffeine

    Science.gov (United States)

    ... Espanol Serious Concerns Over Alcoholic Beverages with Added Caffeine Please share copies of this printer-friendly PDF ( ... beverages, or CABs, are alcoholic beverages that contain caffeine as an additive and are packaged in combined ...

  19. Controlled-release cellulose esters matrices for water-soluble diclofenac sodium: compression and dissolution studies.

    Science.gov (United States)

    Obeidat, W M; Alzoubi, N M

    2014-02-01

    Matrix tablets comprising of a blend of cellulose acetate butyrate (CAB) or cellulose acetate propionate (CAP) and alpha-lactose monohydrate were prepared by direct compression to control the release of diclofenac sodium. Tablet formulations containing CAP75000 or CAB50-54 exhibited highest extents, but lowest onsets of plastic deformation and lowest release rates in buffer medium, while tablets containing CAP15000 or CAB35-39 exhibited lowest extents, but highest rates of plastic deformation and highest release rates in buffer medium. The DA values obtained from Heckel plots and the DI values obtained from Kawakita plots showed similar trends. A plot of compression pressure or crushing strengths against T50% showed curvilinear relationship for all tablets. Tablets containing 40 % CAB35-39 (formulation F7D) was considered the best formulation in terms of T50%, compressibility and compactability. PMID:24640597

  20. NCBI nr-aa BLAST: CBRC-PTRO-07-0067 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  1. NCBI nr-aa BLAST: CBRC-TGUT-05-0032 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  2. NCBI nr-aa BLAST: CBRC-DRER-20-0002 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  3. NCBI nr-aa BLAST: CBRC-TBEL-01-1883 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  4. NCBI nr-aa BLAST: CBRC-TNIG-14-0023 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  5. NCBI nr-aa BLAST: CBRC-GACU-18-0022 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  6. NCBI nr-aa BLAST: CBRC-FRUB-02-0074 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  7. NCBI nr-aa BLAST: CBRC-LAFR-01-1734 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  8. NCBI nr-aa BLAST: CBRC-CJAC-01-1332 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  9. NCBI nr-aa BLAST: CBRC-OLAT-24-0009 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  10. NCBI nr-aa BLAST: CBRC-TNIG-10-0006 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  11. NCBI nr-aa BLAST: CBRC-MMUS-04-0013 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  12. NCBI nr-aa BLAST: CBRC-OANA-01-2200 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  13. NCBI nr-aa BLAST: CBRC-ACAR-01-0845 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  14. NCBI nr-aa BLAST: CBRC-RNOR-05-0081 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  15. NCBI nr-aa BLAST: CBRC-DNOV-01-3023 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0195 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  17. NCBI nr-aa BLAST: CBRC-HSAP-06-0074 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  18. NCBI nr-aa BLAST: CBRC-EEUR-01-1648 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  19. NCBI nr-aa BLAST: CBRC-OCUN-01-1522 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  20. NCBI nr-aa BLAST: CBRC-ETEL-01-1516 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  1. NCBI nr-aa BLAST: CBRC-RMAC-04-0050 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  2. NCBI nr-aa BLAST: CBRC-CFAM-12-0016 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  3. NCBI nr-aa BLAST: CBRC-FCAT-01-1020 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  4. NCBI nr-aa BLAST: CBRC-PABE-07-0058 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available l cannabinoid receptor emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal... cannabinoid receptor type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid

  5. Alcohol Energy Drinks

    Science.gov (United States)

    ... Home / About Addiction / Alcohol / Alcohol Energy Drinks Alcohol Energy Drinks Read 14466 times font size decrease font size increase font size Print Email Alcohol energy drinks (AEDs) or Caffeinated alcoholic beverages (CABs) are ...

  6. 78 FR 71710 - Notice of Application for Approval of Discontinuance or Modification of a Railroad Signal System

    Science.gov (United States)

    2013-11-29

    ... published on April 11, 2000 (65 FR 19477). Robert C. Lauby, Associate Administrator for Railroad Safety... will be provided at all CPs in the event of an onboard cab failure while in route. The reason given...

  7. Children in pickup trucks. American Academy of Pediatrics. Committee on Injury and Poison Prevention.

    Science.gov (United States)

    2000-10-01

    Pickup trucks have become increasingly popular in the United States. A recent study found that in crashes involving fatalities, cargo area passengers were 3 times more likely to die than were occupants in the cab. Compared with restrained cab occupants, the risk of death for those in the cargo area was 8 times higher. Furthermore, the increased use of extended-cab pickup trucks and air bag-equipped front passenger compartments creates concerns about the safe transport of children. The most effective preventive strategies are the legislative prohibition of travel in the cargo area and requirements for age-appropriate restraint use and seat selection in the cab. Parents should select vehicles that are appropriate for the safe transportation needs of the family. Physicians have an important role in counseling families and advocating public policy measures to reduce the number of deaths and injuries to occupants of pickup trucks. PMID:11015537

  8. Geological, biological, and chemical data for Benthic Sediment Baseline Study of Mobile Bay from 3 Apr 1980 to 26 Aug 1981 (NODC Accession 0117430)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Abstract: Beginning in late 1979, the Alabama Coastal Area Board (CAB) funded a series of baseline surveys on the coastal resources of Alabama, from which they...

  9. Biological Data for Biological Baseline Studies of Mobile Bay: Benthic Fauna 1980-1981 (NODC Accession 0116100)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Beginning in late 1979, the Alabama Coastal Area Board (CAB) funded a series of baseline surveys on the coastal resources of Alabama, from which they could develop...

  10. Air service to small communities, directions for the future. [conference

    Science.gov (United States)

    Vittek, J. F., Jr. (Editor)

    1974-01-01

    The seminar on the problems of providing air service to low and medium density points is reported. National transport policies and programs are discussed along with the technology aspects. Recommendations for ATC, CAB, and FAA are included.

  11. The role of abdominal compliance, the neglected parameter in critically ill patients - a consensus review of 16. Part 2: measurement techniques and management recommendations.

    Science.gov (United States)

    Malbrain, Manu L N G; De Laet, Inneke; De Waele, Jan J; Sugrue, Michael; Schachtrupp, Alexander; Duchesne, Juan; Van Ramshorst, Gabrielle; De Keulenaer, Bart; Kirkpatrick, Andrew W; Ahmadi-Noorbakhsh, Siavash; Mulier, Jan; Pelosi, Paolo; Ivatury, Rao; Pracca, Francisco; David, Marcelo; Roberts, Derek J

    2014-01-01

    The recent definitions on intra-abdominal pressure (IAP), intra-abdominal volume (IAV) and abdominal compliance (Cab) are a step forward in understanding these important concepts. They help our understanding of the pathophysiology, aetiology, prognosis, and treatment of patients with low Cab. However, there is still a relatively poor understanding of the different methods used to measure IAP, IAV and Cab and how certain conditions may affect the results. This review will give a concise overview of the different methods to assess and estimate Cab; it will list important conditions that may affect baseline values and suggest some therapeutic options. Abdominal compliance (Cab), defined as a measure of the ease of abdominal expansion, is measured differently than IAP. The compliance of the abdominal wall is only a part of the total abdominal pressure-volume (PV) relationship. Measurement or estimation of Cab is difficult at the bedside and can only be done in a case of change (removal or addition) in IAV. The different measurement techniques will be discussed in relation to decreases (ascites drainage, haematoma evacuation, gastric suctioning) or increases in IAV (gastric insufflation, laparoscopy with CO₂ pneumoperitoneum, peritoneal dialysis). More specific techniques using the interactions between the thoracic and abdominal compartment during positive pressure ventilation will also be discussed (low flow PV loop, respiratory IAP variations, respiratory abdominal variation test, mean IAP and abdominal pressure variation), together with the concept of the polycompartment model. The relation between IAV and IAP is linear at low IAV and becomes curvilinear and exponential at higher volumes. Specific conditions in relation to increased (previous pregnancy or laparoscopy, gynoid fat distribution, ellipse-shaped internal abdominal perimeter) or decreased Cab (obesity, fluid overload, android fat distribution, sphere-shaped internal abdominal perimeter) will be discussed

  12. Information for Authors

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    General Asian Journal ofAndrology (AJA) is the official publication of the Asian Society of Andrology sponsored by the Shanghai Institute of Materia Medica, Chinese Academy of Sciences. The Journal has been included in 11 international indexing systems, including BIOSIS, CAB Abstracts, CAB Health, Chemical Abstracts, Current Contents/Clinical Medicine, EMBASE, Index Medicus, MEDLINE, PASCAL, Research Alert, and SCI Expanded. The Impact Factor is 1.064 and ranks third among the international andrology journals.

  13. Information for Authors

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    1 General Asian Journal of Andrology (AJA) is the official publication of the Asian Society of Andrology sponsored by the Shanghai Institute of Materia Medica, Chinese Academy of Sciences. The Journal has been included in 11 international indexing systems, including BIOSIS, CAB Abstracts, CAB Health, Chemical Abstracts, Current Contents/Clinical Medicine, EMBASE, Index Medicus, MEDLINE, PASCAL, Research Alert, and SCI Expanded. The Impact Factor is 0.827 and ranks third among the international andrology journals.

  14. Using leaf chlorophyll to parameterize light-use-efficiency within a thermal-based carbon, water and energy exchange model

    OpenAIRE

    HOUBORG RASMUS; Anderson, Martha C.; Daughtry, C.S.T.; W. P. Kustas; Rodell, Matthew

    2011-01-01

    Chlorophylls absorb photosynthetically active radiation and thus function as vital pigments for photosynthesis, which makes leaf chlorophyll content (Cab) useful for monitoring vegetation productivity and an important indicator of the overall plant physiological condition. This study investigates the utility of integrating remotely sensed estimates of Cab into a thermal-based Two-Source Energy Balance (TSEB) model that estimates land-surface CO2 and energy fluxes using an analytic...

  15. Antibiofilm Activity of Biosurfactant Producing Coral Associated Bacteria Isolated from Gulf of Mannar

    OpenAIRE

    Padmavathi, Alwar Ramanujam; Pandian, Shunmugiah Karutha

    2014-01-01

    Coral Associated Bacteria (CAB) (N = 22) isolated from the mucus of the coral Acropora digitifera were screened for biosurfactants using classical screening methods; hemolysis test, lipase production, oil displacement, drop collapse test and emulsifying activity. Six CAB (U7, U9, U10, U13, U14, and U16) were found to produce biosurfactants and were identified by 16S ribosomal RNA gene sequencing as Providencia rettgeri, Psychrobacter sp., Bacillus flexus, Bacillus anthracis, Psychrobacter sp....

  16. Cellulose fiber reinforced thermoplastic composites: Processing and Product Charateristics

    OpenAIRE

    Razaina Mat TAIB

    1998-01-01

    Cellulose Fiber-Reinforced Thermoplastic Composites: Process and Product Characterization Razaina Mat Taib ( Abstract ) Steam exploded fibers from Yellow Poplar (Liriodendron tulipifera) wood were assessed in terms of (a) their impact on torque during melt processing of a thermoplastic cellulose ester (plasticized CAB); (b) their fiber incorporation and dispersion characteristics in a CAB-based composite by SEM and image analysis, respectively; and (c) their impact on the me...

  17. Combining Coarse-Grained Protein Models with Replica-Exchange All-Atom Molecular Dynamics

    OpenAIRE

    Andrzej Koliński; Maksim Kouza; Dominik Gront; Sebastian Kmiecik; Jacek Wabik

    2013-01-01

    We describe a combination of all-atom simulations with CABS, a well-established coarse-grained protein modeling tool, into a single multiscale protocol. The simulation method has been tested on the C-terminal beta hairpin of protein G, a model system of protein folding. After reconstructing atomistic details, conformations derived from the CABS simulation were subjected to replica-exchange molecular dynamics simulations with OPLS-AA and AMBER99sb force fields in explicit solvent. Such a combi...

  18. Epidemiology, microbiology and mortality associated with community-acquired bacteremia in northeast Thailand: a multicenter surveillance study.

    Directory of Open Access Journals (Sweden)

    Manas Kanoksil

    Full Text Available BACKGROUND: National statistics in developing countries are likely to underestimate deaths due to bacterial infections. Here, we calculated mortality associated with community-acquired bacteremia (CAB in a developing country using routinely available databases. METHODS/PRINCIPAL FINDINGS: Information was obtained from the microbiology and hospital database of 10 provincial hospitals in northeast Thailand, and compared with the national death registry from the Ministry of Interior, Thailand for the period between 2004 and 2010. CAB was defined in patients who had pathogenic organisms isolated from blood taken within 2 days of hospital admission without a prior inpatient episode in the preceding 30 days. A total of 15,251 CAB patients identified, of which 5,722 (37.5% died within 30 days of admission. The incidence rate of CAB between 2004 and 2010 increased from 16.7 to 38.1 per 100,000 people per year, and the mortality rate associated with CAB increased from 6.9 to 13.7 per 100,000 people per year. In 2010, the mortality rate associated with CAB was lower than that from respiratory tract infection, but higher than HIV disease or tuberculosis. The most common causes of CAB were Escherichia coli (23.1%, Burkholderia pseudomallei (19.3%, and Staphylococcus aureus (8.2%. There was an increase in the proportion of Extended-Spectrum Beta-Lactamases (ESBL producing E. coli and Klebsiella pneumoniae over time. CONCLUSIONS: This study has demonstrated that national statistics on causes of death in developing countries could be improved by integrating information from readily available databases. CAB is neglected as an important cause of death, and specific prevention and intervention is urgently required to reduce its incidence and mortality.

  19. Collaboration among community members, local health service providers, and researchers in an urban research center in Harlem, New York.

    OpenAIRE

    Galea, S.; Factor, S. H.; Bonner, S.; Foley, M; Freudenberg, N; Latka, M; Palermo, A. G.; Vlahov, D

    2001-01-01

    The Urban Research Center at the Center for Urban Epidemiologic Studies brings together community members and researchers working in Harlem, New York. A Community Advisory Board (CAB) composed of community members, service providers, public health professionals, and researchers was formed to assist the Center's research and interventions and to guide community partnerships. Through a collaborative process, the CAB identified three public health problems-substance use, infectious diseases, and...

  20. Controlled and high throughput fabrication of poly(trimethylene terephthalate) nanofibers via melt extrusion of immiscible blends

    International Nuclear Information System (INIS)

    Immiscible blends of cellulose acetate butyrate (CAB) and poly(trimethylene terephthalate) (PTT) were melt extruded through a two strand rod die. The extrudates were hot-drawn at the die exit at different draw ratios. PTT fibers were obtained by removal of the CAB matrix from the drawn extrudates, and the morphology evolution of the formed fibers was investigated by scanning electron microscopy. PTT nanofibers with an average diameter of 55 nm were produced by controlling the drawing ratio.

  1. Cyclic peptides identified by phage display are competitive inhibitors of the tRNA-dependent amidotransferase of Helicobacter pylori.

    Science.gov (United States)

    Pham, Van Hau; Maaroufi, Halim; Levesque, Roger C; Lapointe, Jacques

    2016-05-01

    In Helicobacter pylori, the heterotrimeric tRNA-dependent amidotransferase (GatCAB) is essential for protein biosynthesis because it catalyzes the conversion of misacylated Glu-tRNA(Gln) and Asp-tRNA(Asn) into Gln-tRNA(Gln) and Asn-tRNA(Asn), respectively. In this study, we used a phage library to identify peptide inhibitors of GatCAB. A library displaying loop-constrained heptapeptides was used to screen for phages binding to the purified GatCAB. To optimize the probability of obtaining competitive inhibitors of GatCAB with respect to its substrate Glu-tRNA(Gln), we used that purified substrate in the biopanning process of the phage-display technique to elute phages bound to GatCAB at the third round of the biopanning process. Among the eluted phages, we identified several that encode cyclic peptides rich in Trp and Pro that inhibit H. pylori GatCAB in vitro. Peptides P10 and P9 were shown to be competitive inhibitors of GatCAB with respect to its substrate Glu-tRNA(Gln), with Ki values of 126 and 392μM, respectively. The docking models revealed that the Trp residues of these peptides form π-π stacking interactions with Tyr81 of the synthetase active site, as does the 3'-terminal A76 of tRNA, supporting their competitive behavior with respect to Glu-tRNA(Gln) in the transamidation reaction. These peptides can be used as scaffolds in the search for novel antibiotics against the pathogenic bacteria that require GatCAB for Gln-tRNA(Gln) and/or Asn-tRNA(Asn) formation. PMID:26976271

  2. Bibliometric analysis of systematics production in Latin America

    International Nuclear Information System (INIS)

    I compare six bibliographic databases with information on Latin American systematics: Biosis, CAB, periodica, SCI, scopus and Zoological record. the databases are characterized and compared considering their content, temporal, typological, geographical, thematical coverage, kind of access and new taxon description, to identify which and how many should be used to be more representative. Of the 1363 journals analyzed, 36.5% are found in more than one database and 63.46% are recorded in a single one. zoological record contains 63421 documents, Biosis 19079, CAB 14363, periodica 11185, SCI 3257 and scopus 916. CAB and ZR are the oldest databases, the average number of articles published per year was 6417 for Biosis, 433 for ZR, 361 for periodica, 145 for CAB, 91 for SCI and 30 for Scopus. According to the network analysis, there are stronger relations between SCI and Biosis, which share at least 16% of titles, CAB and Biosis share 15%, Biosis and ZR 14%, and CAB and ZR 11%. Based on the cladogram obtained from a parsimony analysis on the shared journals, the strongest relation is between Biosis and SCI; periodica has the largest number of exclusive journals with 285. ZR has 72.9% of published articles with descriptions of new taxa and an average of 322 a year, CAB 54.6% with 82, and periodica 24.6% with 90. None of databases meets the characteristics to be used as a single source of information, therefore it would be appropriate to use different combinations according to the aim of the analysis. biosis has the most comprehensive information on any current taxon, zoological record and CAB have a broader temporal coverage and include mainly animals or plants, respectively. SCI has the largest number of documents in mainstream journals, with references, citations and bibliometric indicators. periodica has the largest number of documents and temporal coverage published in the area. The cladogram proved to be an optimal visualization tool to represent the main features of

  3. Human Factors Engineering Guidelines for Overhead Cranes

    Science.gov (United States)

    Chandler, Faith; Delgado, H. (Technical Monitor)

    2001-01-01

    This guideline provides standards for overhead crane cabs that can be applied to the design and modification of crane cabs to reduce the potential for human error due to design. This guideline serves as an aid during the development of a specification for purchases of cranes or for an engineering support request for crane design modification. It aids human factors engineers in evaluating existing cranes during accident investigations or safety reviews.

  4. The circulating air barrier: Effective prevention of liquid contaminant movement through soil

    International Nuclear Information System (INIS)

    Objectives of this task included design, modeling, selection of drilling and surface processing equipment, and development of test procedures and cost estimates for conducting a cold test demonstration of the Circulating Air Barrier (CAB) process. The demonstration configuration is scaled to a prototype CAB system designed specifically for the C Tank Farm at the Hanford Site. The CAB system is designed to function as a containment barrier to prevent contamination of the water table located approximately 200 feet below the base of the C-Tank-Farm underground storage tanks. The CAB system is a desiccant-type barrier designed to prevent the migration of liquid contaminants toward the ground water by using an air circulation and processing system to lower the saturation in a targeted subsurface zone below the saturation level required for liquid flow through that zone. The CAB system offers several important advantages, including the fact that it is a non-physical confinement technology, it has an active monitoring and leak detection capability, it is based on proven, commercially available equipment and oil and gas technologies; it has excellent potential for emergency response and rapid deployment; and offers high potential for integration with other remediation technologies. Demonstration- and full-scale CAB systems have been designed for the Hanford Site as part of this task

  5. [A short psychometric scale to evaluate the cognitive status of aged Spanish speakers].

    Science.gov (United States)

    Sánchez-Ayéndez, Melba; Cabán, Carlos A; Fernández, Leticia; Rosich, Walter; Dávila, Ana L; Larriuz, María Celeste; Hernández, Johan; García Guruxarri, Alberto; Palloni, Alberto

    2003-12-01

    During the last ten years there has been an interest for determining the prevalence and incidence of dementia among older adults and for cognitive tests that do to discriminate by level of education. This article revolves around the validation of a minimental exam, the Cabán minimental, to measure the cognitive capacity of Spanish-speaking adults 60 years of age and older; a test that is not affected by level of education. The factors measured in the Cabán minimental are: orientation, visual and motor coordination, learning, recent memory and abstraction. The validation process underwent two phases. During the first one, the Cabán test was subjected to construct validation and internal and predictive consistency tests. The second stage comprised a comparison between the Cabán and Folstein minimentals. The Cabán showed a statistically significant difference to discriminate for subjects with dementia. Results also suggest that the Cabán is not as much affected as the Folstein by differences in education. PMID:14768504

  6. Outcomes associated with conventional versus lipid-based formulations of amphotericin B in propensity-matched groups

    Directory of Open Access Journals (Sweden)

    Campbell RS

    2013-10-01

    Full Text Available Rebecca S Campbell,1 Paresh Chaudhari,2 Harlen D Hays,1 Robert J Taylor,1 Brian H Nathanson,3 Samuel A Bozzette,1 David Horn4 1Cerner Research, Culver City, CA, USA; 2Astellas Scientific and Medical Affairs, Inc., Northbrook, IL, USA; 3OptiStatim, LLC, Longmeadow, MA, USA; 4David Horn LLC, Doylestown, PA, USA Background: Lipid-based formulations of amphotericin B (LF-AMB are indicated for treatment of invasive fungal infections in patients intolerant to conventional amphotericin B (CAB or with refractory infections. Physicians still may choose to administer CAB to such patients. We described the use of CAB and LF-AMB in this population and quantified differences in post-amphotericin B length of stay (LOS among survivors and hospital mortality in matched patients. Methods: Data were extracted from Health Facts (Cerner Corporation, Kansas City, MO, USA for a retrospective cohort analysis. Inpatients aged ≥18 years with evidence of fungal infection and with orders for LF-AMB or CAB on  ≥2 days from January 2001 to June 2010 were identified. Patients were required to have renal insufficiency or other relative contraindications to use of CAB, exposure to nephrotoxic agents, or evidence of a CAB-refractory infection. Multilevel (hierarchical mixed-effects logistic regression was used to determine factors associated with initial exposure to LF-AMB versus CAB. Multivariate adjustment of outcomes was done using propensity score matching. Results: 655 patients were identified: 322 patients initiated therapy with CAB and 333 initiated treatment with LF-AMB. Compared to those initiating CAB, patients initiating LF-AMB had greater acuity and underlying disease severity. In unadjusted analyses, hospital mortality was significantly higher in the LF-AMB group (32.2% versus 23.7%; P = 0.02. After propensity score matching and covariate adjustment, mortality equalized and observed differences in LOS after amphotericin B initiation decreased. Conclusion

  7. Citizen advisory boards: An empirical model for choosing goals and methods

    Energy Technology Data Exchange (ETDEWEB)

    Kunsberg, P.

    1994-12-01

    This is a study of Citizen Advisory Boards (CABS) undertaken for the Department of Energy (DOE) to draw practical insights from the accumulated experience of CAB members and agency officials who have worked with these boards over many years. Hence the main research tool is in-depth interviews of these individuals. In addition, the study relies on field observations of CABs at work, historical documentation of individual boards, and a large body of academic, professional, and government literature. The DOE is in the process of establishing Site Specific Advisory Boards (SSABs) at most of its major facilities in order to provide for community involvement in the DOE environmental restoration and environmental management programs, but these boards initiated by DOE do not yet have enough of a track-record for a study of this type. Consequently, the study focused on CABs at six other federal agencies which have had substantial experience with boards that are similar in composition and purpose to the SSABs. The study examined common problem that confront virtually every CAB in its organization and its decision-making process. For example, each board faces difficult issues in defining its goals and representational responsibilities, selection of members, selection of issues, reaching agreement on recommendations to the parent agency, getting responsive action from the parent agency, and evaluating the board`s success over time. An effort was made to identify solutions or best approaches to these fundamental problems such that the recommended approach has broad application to citizen advisory boards concerned with environmental issues. The conclusions of the study are summarized in a model which incorporates the optimal approaches discovered with respect to each of the critical issues. While acknowledging that the particular circumstances of a CAB may call for individual variations, the model provides a fairly comprehensive description of recommended features of a CAB.

  8. Citizen advisory boards: An empirical model for choosing goals and methods

    International Nuclear Information System (INIS)

    This is a study of Citizen Advisory Boards (CABS) undertaken for the Department of Energy (DOE) to draw practical insights from the accumulated experience of CAB members and agency officials who have worked with these boards over many years. Hence the main research tool is in-depth interviews of these individuals. In addition, the study relies on field observations of CABs at work, historical documentation of individual boards, and a large body of academic, professional, and government literature. The DOE is in the process of establishing Site Specific Advisory Boards (SSABs) at most of its major facilities in order to provide for community involvement in the DOE environmental restoration and environmental management programs, but these boards initiated by DOE do not yet have enough of a track-record for a study of this type. Consequently, the study focused on CABs at six other federal agencies which have had substantial experience with boards that are similar in composition and purpose to the SSABs. The study examined common problem that confront virtually every CAB in its organization and its decision-making process. For example, each board faces difficult issues in defining its goals and representational responsibilities, selection of members, selection of issues, reaching agreement on recommendations to the parent agency, getting responsive action from the parent agency, and evaluating the board's success over time. An effort was made to identify solutions or best approaches to these fundamental problems such that the recommended approach has broad application to citizen advisory boards concerned with environmental issues. The conclusions of the study are summarized in a model which incorporates the optimal approaches discovered with respect to each of the critical issues. While acknowledging that the particular circumstances of a CAB may call for individual variations, the model provides a fairly comprehensive description of recommended features of a CAB

  9. Caffeinated and non-caffeinated alcohol use and indirect aggression: The impact of self-regulation.

    Science.gov (United States)

    Sheehan, Brynn E; Linden-Carmichael, Ashley N; Lau-Barraco, Cathy

    2016-07-01

    Research shows that heavier alcohol use is associated with physical aggression. Scant research has examined the way in which alcohol relates to other forms of aggression, such as indirect aggression (e.g., malicious humor, social exclusion). Given the possible negative consequences of indirect aggression and the limited evidence suggesting alcohol use can elicit indirectly aggressive responses, research is needed to further investigate the association between drinking behavior and indirect aggression. Additionally, specific alcoholic beverages, such as caffeinated alcoholic beverages (CABs; e.g., Red Bull and vodka), may potentiate aggression above the influence of typical use, and thus warrant examination with regard to indirect aggression. One factor that may impact the strength of the alcohol-indirect aggression and CAB-indirect aggression relationships is one's level of self-regulation. Consequently, our study examined the relationships between (1) alcohol use and indirect aggression, (2) CAB use and indirect aggression, and (3) self-regulation as a moderator. Participants were 733 (67.6% female) undergraduate students who reported their CAB and alcohol use, self-regulation, and aggressive behaviors. Results revealed that heavier alcohol use was associated with more frequent indirect aggression after controlling for dispositional aggression. Heavier CAB use was related to more frequent indirect aggression after accounting for typical use and dispositional aggression. Self-regulation moderated these associations such that for those with lower self-regulation, greater alcohol and CAB consumption was associated with greater indirect aggression. Our findings suggest that heavier alcohol and CAB consumption may be risk factors for engaging in indirect aggression and this risk is impacted by one's regulatory control. PMID:26905765

  10. Disease stress detection on citrus using a leaf optical model and field spectroscopy

    Science.gov (United States)

    Badnakhe, Mrunalini R.; Durbha, Surya; Adinarayana, J.

    2015-10-01

    As citrus is progressively contributing to horticultural production, wealth and economy of a country, it is necessary to understand the factors impacting citrus production. Gummosis is one of the most serious diseases causing considerable loss of overall citrus production and yield quality. A qualitative and quantitative analysis of citrus leaf biochemical properties are necessary to monitor the crop health, disease /pest stress and production. Total leaf chlorophyll content (Cab) represents one of the key biochemical factors which contributes in water, carbon, and energy exchange processes. Photosynthesis process in citrus will be disturbed as gummosis disease life cycle progresses. It is important to study Cab to evaluate the photosynthesis rate and disease stress. In this study the potential of Radiative Transfer (RT) PROSPECT model to retrieve Cab in citrus orchards was undertaken at different sites. The main goal is to evaluate the relationship between Cab and gummosis disease stress for citrus at various phenological stages. Inversion of PROSPECT model on measured hyperspectral data is carried out to extract the leaf level parameters influencing the disease. This model was inverted with the ground truth hyperspectral reading. The testing was separately initiated for healthy and infected plant leaves. This can lead to understand the disease stress on citrus leaves. For accuracy, raw spectra are filtered and processed which is an input parameter for Inversion PROSPECT model. Here, retrieved Cab content was correlated with gummosis disease stress in terms of oozing with R2 = 0.6021 and RMSE= 0.481272.

  11. Study on the hardening mechanism of cement asphalt binder

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The hydration and hardening mechanism of cement asphalt binder(CAB) was studied.The early hydration process,hydration products and paste microstructure of CAB made by Portland cement and anionic asphalt emulsion were investigated by calorimetry,X-ray diffraction,and environmental scanning electron microscopy.The early hydration process of CAB can be characterized as 5 stages similar to those of Portland cement.There is no chemical reaction detected between cement and asphalt,hence no new hydration products other than those of Portland cement are produced.The hardening of CAB begins with the hydration of cement.When the hydration of cement comes into the acceleration period and its exothermic rate comes to the maximum,the coalescence of asphalt particles in asphalt emulsion is triggered.In the hardened system of CAB,it was found that the hydration products of cement form the skeleton and are covered by the continuous asphalt film.They formed an interpenetrating network system.The emulsifiers in the asphalt emulsion may retard the hydration process of cement.

  12. Purification and immunochemical characterization of the cytoplasmic androgen-binding protein of rat liver

    International Nuclear Information System (INIS)

    The cytoplasmic androgen-binding (CAB) protein of the male rate liver has been implicated to play a role in the androgen-dependent regulation of α2u-globulin synthesis. The liver of the adult male rat contains about 50 fmol of specific high-affinity androgen-binding activity per milligram of total cytosolic protein. Photoaffinity labeling with [3H]R-1881 followed by SDS-polyacrylamide gel electrophoresis and autoradiography shows that the CAB is a 31-kilodalton protein. By means of DEAE-cellulose chromatography and preparative SCS-polyacrylamide gel electrophoresis, the authors have purified the CAB protein to electrophoretic homogeneity and have raised polyclonal rabbit antiserum that is monospecific to this protein. In the sucrose density gradient, the antiserum reacted with the androgen-binding component of the male liver cytosol prelabeled with tritiated dihydrotestosterone. Western blot analysis of the liver cytosol showed that the antiserum recognizes only the 31-kDa androgen-binding component. Such immunoblotting also showed that unlike the young adult, the androgen-insensitive states during prepuberty and senescence are associated with a marked reduction in the hepatic concentration of the immunoreactive CAB protein. No immunochemical cross-reactivity between CAB and another androgen-binding component of Mr 29K was observed. The latter finding favors the possibility that 31- and 29-kDa androgen-binding components may have distinct sequence structure

  13. Cine Club

    CERN Multimedia

    Cine Club

    2015-01-01

    Thursday 19 February 2015 at 20:00 CERN Council Chamber Mystery Train     Directed by Jim Jarmusch - USA, 1989, 110 minutes A Japanese couple obsessed with 1950s America goes to Memphis because the male half of the couple emulates Carl Perkins. Chance encounters link three different stories in the city, with the common thread being the seedy hotel where they are all staying. Original version English; French subtitles   Thursday 26 February 2015 at 20:00 CERN Council Chamber Night on Earth     Directed by Jim Jarmusch - USA, 1991, 129 minutes A collection of five stories involving cab drivers in five different cities. Los Angeles - A talent agent for the movies discovers her cab driver would be perfect to cast, but the cabbie is reluctant to give up her solid cab driver's career. New York - An immigrant cab driver is continually lost in a city and culture he doesn't understand. Paris - A blind girl takes a ride with a cab driv...

  14. GnRH agonists and the rapidly increasing use of combined androgen blockade in prostate cancer.

    Science.gov (United States)

    Labrie, Fernand

    2014-08-01

    The discovery of medical castration with GnRH agonists in 1979 rapidly replaced surgical castration and high doses of estrogens for the treatment of prostate cancer. Soon afterwards, it was discovered that androgens were made locally in the prostate from the inactive precursor DHEA of adrenal origin, a mechanism called intracrinology. Taking into account these novel facts, combined androgen blockade (CAB) using a pure antiandrogen combined with castration in order to block the two sources of androgens was first published in 1982. CAB was the first treatment shown in randomized and placebo-controlled trials to prolong life in prostate cancer, even at the metastatic stage. Most importantly, the results recently obtained with the novel pure antiandrogen enzalutamide as well as with abiraterone, an inhibitor of 17α-hydroxylase in castration-resistant prostate cancer, has revitalized the CAB concept. The effects of CAB observed on survival of heavily pretreated patients further demonstrates the importance of the androgens made locally in the prostate and are a strong motivation to apply CAB to efficiently block all sources of androgens earlier at start of treatment and, even better, before metastasis occurs. The future of research in this field thus seems to be centered on the development of more potent blockers of androgens formation and action in order to obtain better results at the metastatic stage and, for the localized stage, reduce the duration of treatment required to achieve complete apoptosis and control of prostate cancer proliferation before it reaches the metastatic or noncurable stage. PMID:24825748

  15. CoolCalc: A Long-Haul Truck Thermal Load Estimation Tool

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J. A.; Rugh, J. P.; Rister, B. R.; Venson, T. S.

    2011-01-01

    In the United States, intercity long-haul trucks idle approximately 1,800 hrs annually for sleeper cab hotel loads, consuming 838 million gallons of diesel fuel per year. The objective of the CoolCab project is to work closely with industry to design efficient thermal management systems for long-haul trucks that keep the cab comfortable with minimized engine idling. Truck engine idling isprimarily done to heat or cool the cab/sleeper, keep the fuel warm in cold weather, and keep the engine warm for cold temperature startup. Reducing the thermal load on the cab/sleeper will decrease air conditioning system requirements, improve efficiency, and help reduce fuel use. CoolCalc is an easy-to-use, simplified, physics-based HVAC load estimation tool that requires no meshing, hasflexible geometry, excludes unnecessary detail, and is less time-intensive than more detailed computer-aided engineering modeling approaches. It is intended for rapid trade-off studies, technology impact estimation, and preliminary HVAC sizing design and to complement more detailed and expensive CAE tools by exploring and identifying regions of interest in the design space. This paper describesthe CoolCalc tool, provides outdoor long-haul truck thermal testing results, shows validation using these test results, and discusses future applications of the tool.

  16. Prolactinomas, cabergoline, and pregnancy.

    Science.gov (United States)

    Glezer, Andrea; Bronstein, Marcello D

    2014-09-01

    Hyperprolactinemia, frequently caused by a prolactinoma, is an important cause of infertility among young women. Dopamine agonists (DA) are the treatment of choice. Although cabergoline (CAB) is currently considered the gold standard DA, bromocriptine (BRC) remains the drug of choice for women desiring pregnancy, as it was proven to be safe in more than 6,000 pregnancies. The purpose of this review is to perform a critical evaluation of CAB safety in pregnancy, as it is used by most patients harboring prolactinomas. Although the number of CAB-induced pregnancies (about 800) is still reduced as compared with those under BRC treatment, data in the literature do not point to increase risk of preterm delivery or fetal malformations, comparing to pregnancies induced by BRC and those in the general population. Moreover, CAB use throughout pregnancy was reported in about ten cases, without evidence of any harm to fetal development. Therefore, even though BRC still remains the recommended DA drug for pregnancy induction or use during pregnancy in women with prolactinomas, increasing evidences point to the safety of CAB for this purpose. PMID:24985062

  17. Hippocampal volume and cingulum bundle fractional anisotropy are independently associated with verbal memory in older adults.

    Science.gov (United States)

    Ezzati, Ali; Katz, Mindy J; Lipton, Michael L; Zimmerman, Molly E; Lipton, Richard B

    2016-09-01

    The objective of this study was to investigate the relationship of medial temporal lobe and posterior cingulate cortex (PCC) volumetrics as well as fractional anisotropy of the cingulum angular bundle (CAB) and the cingulum cingulate gyrus (CCG) bundle to performance on measures of verbal memory in non-demented older adults. The participants were 100 non-demented adults over the age of 70 years from the Einstein Aging Study. Volumetric data were estimated from T1-weighted images. The entire cingulum was reconstructed using diffusion tensor MRI and probabilistic tractography. Association between verbal episodic memory and MRI measures including volume of hippocampus (HIP), entorhinal cortex (ERC), PCC and fractional anisotropy of CAB and CCG bundle were modeled using linear regression. Relationships between atrophy of these structures and regional cingulum fractional anisotropy were also explored. Decreased HIP volume on the left and decreased fractional anisotropy of left CAB were associated with lower memory performance. Volume changes in ERC, PCC and CCG disruption were not associated with memory performance. In regression models, left HIP volume and left CAB-FA were each independently associated with episodic memory. The results suggest that microstructural changes in the left CAB and decreased left HIP volume independently influence episodic memory performance in older adults without dementia. The importance of these findings in age and illness-related memory decline require additional exploration. PMID:26424564

  18. Transparent Blend of Poly(Methylmethacrylate/Cellulose Acetate Butyrate for the Protection from Ultraviolet

    Directory of Open Access Journals (Sweden)

    Raouf Mahmood Raouf

    2016-04-01

    Full Text Available The use of transparent polymers as an alternative to glass has become widespread. However, the direct exposure of these materials to climatic conditions of sunlight and heat decrease the lifetime cost of these products. The aim of this study was to minimize the harm caused by ultraviolet (UV radiation exposure to transparent poly(methylmethacrylate (PMMA, which usually leads to changes in the physical and chemical properties of these materials and reduced performance. This was achieved using environmentally friendly cellulose acetate butyrate (CAB. The optical, morphological, and thermal properties of CAB blended with transparent PMMA was studied using UV-VIS spectrophotometry, scanning electron microscopy, X-ray diffraction, dynamic mechanical analysis, and thermal gravimetric analysis. The results show that CAB was able to reduce the effects of UV radiation by making PMMA more transparent to UV light, thereby preventing the negative effects of trapped radiation within the compositional structure, while maintaining the amorphous structure of the blend. The results also show that CAB blended with PMMA led to some properties commensurate with the requirements of research in terms of a slight increase in the value of the modulus and the glass transition temperature for the PMMA/CAB blend.

  19. Suplemento múltiplo com ionóforos para novilhos em pasto: desempenho

    OpenAIRE

    M.H.F. Mourthe; R.B. Reis; M.M. Ladeira; R.C. Souza; S.G. Coelho; H.M. Saturnino

    2011-01-01

    Avaliou-se o desempenho de 25 novilhos Holandês x Zebu, castrados, com média de peso vivo inicial de 265±50 kg, sob pastejo emBrachiaria decumbens, distribuídos em cinco grupos e em cinco piquetes, segundo os tratamentos: controle - suplementação múltipla sem ionóforos (CONT); suplementação múltipla com 100mg/cab/dia de monensina (M100); suplementação múltipla com 200mg/cab/dia de monensina (M200); suplementação múltipla com 100mg/cab/dia de lasalocida (L100); suplementação múltipla com 200mg...

  20. Enabling the Tablet Product Development of 5-Fluorocytosine by Conjugate Acid Base Cocrystals.

    Science.gov (United States)

    Perumalla, Sathyanarayana R; Paul, Shubhajit; Sun, Changquan C

    2016-06-01

    5-Fluorocytosine (FC) is a high-dose antifungal drug that challenges the development of a tablet product due to poor solid-state stability and tabletability. Using 2 pharmaceutically acceptable conjugate acid base (CAB) cocrystals of FC with HCl and acesulfame, we have developed commercially viable high loading FC tablets. The tablets were prepared by direct compression using nano-coated microcrystalline cellulose Avicel PH105 as a tablet binder, which provided both excellent tabletability and good flowability. Commercial manufacturability of formulations based on both CAB cocrystals was verified on a compaction simulator. The results from an expedited friability study were used to set the compaction force, which yielded tablets with sufficient mechanical strength and rapid tablet disintegration. This work demonstrates the potential value of CAB cocrystals in drug product development. PMID:27238493

  1. Highly Scalable Trip Grouping for Large Scale Collective Transportation Systems

    DEFF Research Database (Denmark)

    Gidofalvi, Gyozo; Pedersen, Torben Bach; Risch, Tore;

    2008-01-01

    techniques and support input rates that can be orders of magnitude larger. The following three contributions make the grouping algorithms scalable. First, the basic grouping algorithm is expressed as a continuous stream query in a data stream management system to allow for a very large flow of requests......Transportation-related problems, like road congestion, parking, and pollution, are increasing in most cities. In order to reduce traffic, recent work has proposed methods for vehicle sharing, for example for sharing cabs by grouping "closeby" cab requests and thus minimizing transportation cost and...... utilizing cab space. However, the methods published so far do not scale to large data volumes, which is necessary to facilitate large-scale collective transportation systems, e.g., ride-sharing systems for large cities. This paper presents highly scalable trip grouping algorithms, which generalize previous...

  2. Diagnosis and medical treatment of prolactinomas

    International Nuclear Information System (INIS)

    The first-line treatment of prolactinomas is medical therapy with dopamine receptor agonists. Bromocriptine (BC) has been used over the past 30 years, while cabergoline (CAB) is increasingly used in recent years because of its enhanced efficacy and better tolerability. Cabergoline is highly effective in normalizing elevated prolactin, recovering hypogonadism, and achieving a successful pregnancy in patients with tumoral and non-tumoral hyperprolactinemia. Also, CAB has a greater ability to shrink prolactinomas (PRLomas) than BC and often extinguishes them. Regarding the diagnosis, it requires demonstrating hyperprolactinemia on at least two separate occasions, excluding other causes of hyperprolactinemia than PRLomas, and detecting pituitary tumor on magnetic resonance imaging. Final diagnosis in non-operated cases is made empirically by attaining unequivocal tumor shrinkage or disappearance with CAB treatment. (author)

  3. Fem års koronararteriebypasskirurgi (1995-2000) på Odense Universitetshospital

    DEFF Research Database (Denmark)

    Ømark, Henrik; Gregersen, Nanna; Clausen, Betina;

    2005-01-01

    -three percent were elective operations, and 7% were acute. The risk score estimated 20% of the patients to be in high-risk groups, 22% in the 5% group and 53% in the low-risk group. There was three-vessel disease in 68% and left main stenosis in 24%. The EF was normal in 73% of the patients, while 4% had EF <30......%. RESULTS: The total early mortality rate was 3%, the primary elective CABS rate was 2.6%, and we found a statistically significant higher mortality for elective reoperations (5.9%) and for acute CABS (7%). Comparison with the Danish background population indicates a better survival rate for the CABS...... had a statistically significant higher late mortality rate. About 20% suffered from recurrent angina in the observation period, one-fourth had wound healing of the graft leg and 96% did not regret the operation. DISCUSSION: Apart from the rather high reoperation rate because of bleeding and the...

  4. Comparison of two methodologies to estimate microbial activity in a pumpkin crop (Cucurbita maxima) in blooming and maturity phases

    International Nuclear Information System (INIS)

    The measure of soil microbial activity is a significant feature in fertility and conservation diagnostic thinking about it, we compared two methodologies: volumetric Calcimeter that measures CO2 released by soil into closed atmospheric system (glass tubes), cab method that retains CO2 released during incubation phase in a closed system (glass bottles) at 23 degrades celsius subsequently titrate with HCL 0.5N. Results showed microbial activity in a pumpkin crop (Cucurbita maxima) in Palmira, Valle del Cauca - Colombia, is higher in maturity than blooming phase. It occurs beca use contribution of nutritive substances from pumpkin's roots as it is in physiological maturity and microclimate offered by full foliage of pumpkin. Because in CAB method, soil is put on trial with its natural wet the numeric results express as mgC-CO2.g1 of soil are most reliable than volumetric Calcimeter method. The cost analysis showed that cab is twenty percent cheaper than volumetric Calcimeter method

  5. Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jing; Bu, Weishu; Sheppard, Kelly; Kitabatake, Makoto; Kwon, Suk-Tae; Söll, Dieter; Smith, Janet L.; (Yale); (Michigan); (Kyoto)

    2010-08-17

    Many bacteria form Gln-tRNA{sup Gln} and Asn-tRNA{sup ASN} by conversion of the misacylated Glu-tRNA{sup Gln} and Asp-tRNA{sup ASN} species catalyzed by the GatCAB amidotransferase in the presence of ATP and an amide donor (glutamine or asparagine). Here, we report the crystal structures of GatCAB from the hyperthermophilic bacterium Aquifex aeolicus, complexed with glutamine, asparagine, aspartate, ADP, or ATP. In contrast to the Staphylococcus aureus GatCAB, the A. aeolicus enzyme formed acyl-enzyme intermediates with either glutamine or asparagine, in line with the equally facile use by the amidotransferase of these amino acids as amide donors in the transamidation reaction. A water-filled ammonia channel is open throughout the length of the A. aeolicus GatCAB from the GatA active site to the synthetase catalytic pocket in the B-subunit. A non-catalytic Zn{sup 2+} site in the A. aeolicus GatB stabilizes subunit contacts and the ammonia channel. Judged from sequence conservation in the known GatCAB sequences, the Zn{sup 2+} binding motif was likely present in the primordial GatB/E, but became lost in certain lineages (e.g., S. aureus GatB). Two divalent metal binding sites, one permanent and the other transient, are present in the catalytic pocket of the A. aeolicus GatB. The two sites enable GatCAB to first phosphorylate the misacylated tRNA substrate and then amidate the activated intermediate to form the cognate products, Gln-tRNA{sup Gln} or Asn-tRNA{sup ASN}.

  6. A novel mechanism for antibody-based anthrax toxin neutralization: inhibition of prepore-to-pore conversion.

    Science.gov (United States)

    Mechaly, Adva; Levy, Haim; Epstein, Eyal; Rosenfeld, Ronit; Marcus, Hadar; Ben-Arie, Einat; Shafferman, Avigdor; Ordentlich, Arie; Mazor, Ohad

    2012-09-21

    Protective antigen (PA), a key component of anthrax toxin, mediates the entry of lethal factor (LF) or edema factor (EF) through a membranal pore into target cells. We have previously reported the isolation and chimerization of cAb29, an anti-PA monoclonal antibody that effectively neutralizes anthrax toxin in an unknown mechanism. The aim of this study was to elucidate the neutralizing mechanism of this antibody in vitro and to test its ability to confer post-exposure protection against anthrax in vivo. By systematic evaluation of the steps taking place during the PA-based intoxication process, we found that cAb29 did not interfere with the initial steps of intoxication, namely its ability to bind to the anthrax receptor, the consecutive proteolytic cleavage to PA(63), oligomerization, prepore formation, or LF binding. However, the binding of cAb29 to the prepore prevented its pH-triggered transition to the transmembranal pore, thus preventing the last step of intoxication, i.e. the translocation of LF/EF into the cell. Epitope mapping, using a phage display peptide library, revealed that cAb29 binds the 2α(1) loop in domain 2 of PA, a loop that undergoes major conformational changes during pore formation. In vivo, we found that 100% of anthrax-infected rabbits survived when treated with cAb29 12 h after exposure. In conclusion, these experiments demonstrate that cAb29 exerts its potent neutralizing activity in a unique manner by blocking the prepore-to-pore conversion process. PMID:22869370

  7. Advances of evolutionary computation methods and operators

    CERN Document Server

    Cuevas, Erik; Oliva Navarro, Diego Alberto

    2016-01-01

    The goal of this book is to present advances that discuss alternative Evolutionary Computation (EC) developments and non-conventional operators which have proved to be effective in the solution of several complex problems. The book has been structured so that each chapter can be read independently from the others. The book contains nine chapters with the following themes: 1) Introduction, 2) the Social Spider Optimization (SSO), 3) the States of Matter Search (SMS), 4) the collective animal behavior (CAB) algorithm, 5) the Allostatic Optimization (AO) method, 6) the Locust Search (LS) algorithm, 7) the Adaptive Population with Reduced Evaluations (APRE) method, 8) the multimodal CAB, 9) the constrained SSO method.

  8. Ballmilling of metal borohydrides for hydrogen storage

    DEFF Research Database (Denmark)

    Sommer, Sanna

    2014-01-01

    ’s dehydrogenated state. Specifically, the research undertaken targets CaB6 whose boron is in a octahedral network, or AlB2 whose boron is layered. These compounds were then reactive ball milled with alkali and alkaline earth metal under hydrogen pressure, with the intention of forming metal borohydrides. For CaB6...... investigation is to hydrogenate simple compounds such as metalborides and hydrides with the intention of forming a new and more hydrogen rich borohydride. In contrast to mainstream research, the method of synthesis has been based on reactants that are expected to be found in the metal borohydride...

  9. PdMn and PdFe: New Materials for Temperature Measurement Near 2K

    International Nuclear Information System (INIS)

    Interest in the critical dynamics of superfluid 4 He in microgravity conditions has motivated the development of new high resolution thermometry technol- ogy for use in space experiments near 2K. The current material commonly used as the temperature sensing element for high resolution thermometers (HRTs) is copper ammonium bromide [Cu(NH4)2Br42H20) or ''CAB'', which undergoes a ferromagnetic phase transition at 1.8K1. HRTs made from CAB have demonstrated low drift (-13 K/s

  10. Population dynamics of Virginia's hunted black bear (Ursus americanus) population.

    OpenAIRE

    Klenzendorf, Sybille A.

    2002-01-01

    The Cooperative Alleghany Bear Study (CABS) was initiated in 1994 by the Virginia Department of Game and Inland Fisheries (VDGIF) and the Virginia Polytechnic Institute and State University (VPI&SU) to investigate population dynamics on Virginiaâ s hunted bear population. CABS personnel handled 746 different bears (1.5M:1F) 1,368 times on its northern study area during June 1994 to September 2000. The sex ratio for summer captures was 1.5M:1F, which differed from 1:1 (n = 1,008, Z = 6.17,...

  11. Cloning, characterization, and heterologous expression of the Saccharopolyspora erythraea (Streptomyces erythraeus) gene encoding an EF-hand calcium-binding protein.

    OpenAIRE

    Swan, D G; Cortes, J; Hale, R S; Leadlay, P F

    1989-01-01

    The regulatory effects of Ca2+ in eucaryotic cells are mostly mediated by a superfamily of Ca2+-binding proteins (CABs) that contain one or more characteristic Ca2+-binding structural motifs, referred to as EF hands. We have cloned and sequenced the structural gene for an authentic EF-hand CAB from the spore-forming gram-positive bacterium Saccharopolyspora erythraea (formerly Streptomyces erythraeus). When the gene was introduced into Streptomyces lividans on the high-copy plasmid vector pIJ...

  12. Analysis of Two Putative Candida albicans Phosphopantothenoylcysteine Decarboxylase / Protein Phosphatase Z Regulatory Subunits Reveals an Unexpected Distribution of Functional Roles

    Science.gov (United States)

    Petrényi, Katalin; Molero, Cristina; Kónya, Zoltán; Erdődi, Ferenc; Ariño, Joaquin; Dombrádi, Viktor

    2016-01-01

    Protein phosphatase Z (Ppz) is a fungus specific enzyme that regulates cell wall integrity, cation homeostasis and oxidative stress response. Work on Saccharomyces cerevisiae has shown that the enzyme is inhibited by Hal3/Vhs3 moonlighting proteins that together with Cab3 constitute the essential phosphopantothenoylcysteine decarboxylase (PPCDC) enzyme. In Candida albicans CaPpz1 is also involved in the morphological changes and infectiveness of this opportunistic human pathogen. To reveal the CaPpz1 regulatory context we searched the C. albicans database and identified two genes that, based on the structure of their S. cerevisiae counterparts, were termed CaHal3 and CaCab3. By pull down analysis and phosphatase assays we demonstrated that both of the bacterially expressed recombinant proteins were able to bind and inhibit CaPpz1 as well as its C-terminal catalytic domain (CaPpz1-Cter) with comparable efficiency. The binding and inhibition were always more pronounced with CaPpz1-Cter, indicating a protective effect against inhibition by the N-terminal domain in the full length protein. The functions of the C. albicans proteins were tested by their overexpression in S. cerevisiae. Contrary to expectations we found that only CaCab3 and not CaHal3 rescued the phenotypic traits that are related to phosphatase inhibition by ScHal3, such as tolerance to LiCl or hygromycin B, requirement for external K+ concentrations, or growth in a MAP kinase deficient slt2 background. On the other hand, both of the Candida proteins turned out to be essential PPCDC components and behaved as their S. cerevisiae counterparts: expression of CaCab3 and CaHal3 rescued the cab3 and hal3 vhs3 S. cerevisiae mutations, respectively. Thus, both CaHal3 and CaCab3 retained the PPCDC related functions and have the potential for CaPpz1 inhibition in vitro. The fact that only CaCab3 exhibits its phosphatase regulatory potential in vivo suggests that in C. albicans CaCab3, but not CaHal3, acts as a

  13. Improvement of operator's environment in excavator

    OpenAIRE

    Håkansson, Jon

    2004-01-01

    According to the report Ergonomic on-Site Assessment of Excavator Work, one big problem is the risk of falling accidents when entering and exiting the cab. The solution could be lowering the cab to the ground in front of the machine, this could also help during cleaning of windows. The mechanism needed for this operation could also be used for adjusting the cabin in height and tilting it, in order to solve the problem with neck and back injuries. In Umeå I had a meeting with professor Ivan We...

  14. Thermal-hydraulic characteristics of the RBMK control and protection system channels

    International Nuclear Information System (INIS)

    The thermal-hydraulic characteristics of the RBMK-1000 control and protection system channel with rod cluster control have been calculated under different operational disturbance regimes. It has been shown that the temperature of the rod cluster control structural materials increases considerably if loss of coolant occurs. The critical element is the sleeve made of CAB1 aluminum alloy

  15. Correction of the dynamic blur in liver scintigraphy by microcomputer and associated microelectronics

    International Nuclear Information System (INIS)

    The liver scintigraphic images can be blurred. This blur falsifies the interpretation of these images for a diagnostic. A pre-processing is necessary. We define the liver movement, together with theoretical approaches for its correction. A real time corrector is proposed, this microcomputerized system with associated microelectronics is gathered around a fast processor, the ''cab''

  16. Sequence Classification: 785961 [

    Lifescience Database Archive (English)

    Full Text Available hways (157.5 kD) (aex-3) || http://www.ncbi.nlm.nih.gov/protein/25147747 ... ...ulsion defective AEX-3, Rab3 Guanine nucleotide Exchange Factor, regulator of presynaptic activity, regulates the rab-3 and cab-1 pat

  17. 49 CFR 236.722 - Circuit, cut-in.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Circuit, cut-in. 236.722 Section 236.722 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Circuit, cut-in. A roadway circuit at the entrance to automatic train stop, train control or cab...

  18. 49 CFR 236.563 - Delay time.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Delay time. 236.563 Section 236.563 Transportation... Cab Signal Systems Rules and Instructions; Locomotives § 236.563 Delay time. Delay time of automatic... requirements of § 236.24 shall take into consideration the delay time....

  19. 49 CFR 236.564 - Acknowledging time.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Acknowledging time. 236.564 Section 236.564..., Train Control and Cab Signal Systems Rules and Instructions; Locomotives § 236.564 Acknowledging time. Acknowledging time of intermittent automatic train-stop device shall be not more than 30 seconds....

  20. NCBI nr-aa BLAST: CBRC-CELE-02-0102 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CELE-02-0102 ref|NP_495888.2| T07D4.1 [Caenorhabditis elegans] emb|CAA90404.3|... Hypothetical protein T07D4.1 [Caenorhabditis elegans] emb|CAB76411.2| Hypothetical protein T07D4.1 [Caenorhabditis elegans] NP_495888.2 0.0 89% ...

  1. NCBI nr-aa BLAST: CBRC-MMUR-01-0557 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUR-01-0557 ref|NP_510481.1| hypothetical protein F45B8.3 [Caenorhabditis elegan...s] emb|CAB05726.2| C. elegans protein F45B8.3, confirmed by transcript evidence [Caenorhabditis elegans] NP_510481.1 8e-04 30% ...

  2. NCBI nr-aa BLAST: CBRC-CBRE-01-0902 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRE-01-0902 ref|NP_001040957.1| JC8.12a [Caenorhabditis elegans] gb|AAK49908....1| JC8.12-like protein [Caenorhabditis elegans] emb|CAB54268.2| Hypothetical protein JC8.12a [Caenorhabditis elegans] NP_001040957.1 2e-80 67% ...

  3. NCBI nr-aa BLAST: CBRC-CBRI-01-0011 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRI-01-0011 ref|NP_492273.1| F16D3.7 [Caenorhabditis elegans] emb|CAB01500.1|... Hypothetical protein F16D3.7 [Caenorhabditis elegans] emb|CAA16515.1| Hypothetical protein F16D3.7 [Caenorhabditis elegans] NP_492273.1 0.0 79% ...

  4. NCBI nr-aa BLAST: CBRC-CELE-04-0119 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CELE-04-0119 ref|NP_001040957.1| JC8.12a [Caenorhabditis elegans] gb|AAK49908....1| JC8.12-like protein [Caenorhabditis elegans] emb|CAB54268.2| Hypothetical protein JC8.12a [Caenorhabditis elegans] NP_001040957.1 1e-175 100% ...

  5. NCBI nr-aa BLAST: CBRC-CBRE-01-1159 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRE-01-1159 ref|NP_492273.1| F16D3.7 [Caenorhabditis elegans] emb|CAB01500.1|... Hypothetical protein F16D3.7 [Caenorhabditis elegans] emb|CAA16515.1| Hypothetical protein F16D3.7 [Caenorhabditis elegans] NP_492273.1 0.0 77% ...

  6. NCBI nr-aa BLAST: CBRC-CREM-01-1184 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CREM-01-1184 ref|NP_001040957.1| JC8.12a [Caenorhabditis elegans] gb|AAK49908....1| JC8.12-like protein [Caenorhabditis elegans] emb|CAB54268.2| Hypothetical protein JC8.12a [Caenorhabditis elegans] NP_001040957.1 1e-121 70% ...

  7. NCBI nr-aa BLAST: CBRC-CBRE-01-0098 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CBRE-01-0098 ref|NP_507941.2| B0250.9 [Caenorhabditis elegans] gb|AAQ14296.1|A...F264764_1 sterol reductase [Caenorhabditis elegans] emb|CAB03797.2| Hypothetical protein B0250.9 [Caenorhabditis elegans] NP_507941.2 2e-59 81% ...

  8. NCBI nr-aa BLAST: CBRC-CREM-01-0535 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CREM-01-0535 ref|NP_492273.1| F16D3.7 [Caenorhabditis elegans] emb|CAB01500.1|... Hypothetical protein F16D3.7 [Caenorhabditis elegans] emb|CAA16515.1| Hypothetical protein F16D3.7 [Caenorhabditis elegans] NP_492273.1 0.0 83% ...

  9. NCBI nr-aa BLAST: CBRC-CELE-01-0020 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CELE-01-0020 ref|NP_492273.1| F16D3.7 [Caenorhabditis elegans] emb|CAB01500.1|... Hypothetical protein F16D3.7 [Caenorhabditis elegans] emb|CAA16515.1| Hypothetical protein F16D3.7 [Caenorhabditis elegans] NP_492273.1 0.0 96% ...

  10. NCBI nr-aa BLAST: CBRC-CREM-01-1287 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CREM-01-1287 ref|NP_001040957.1| JC8.12a [Caenorhabditis elegans] gb|AAK49908....1| JC8.12-like protein [Caenorhabditis elegans] emb|CAB54268.2| Hypothetical protein JC8.12a [Caenorhabditis elegans] NP_001040957.1 1e-119 71% ...

  11. NCBI nr-aa BLAST: CBRC-DSIM-04-0030 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-DSIM-04-0030 ref|NP_001011594.1| G-protein coupled receptor [Apis mellifera] e...mb|CAB76374.1| G-protein coupled receptor [Apis mellifera] gb|ABI94393.1| tyramine receptor [Apis mellifera]... gb|ABI94394.1| tyramine receptor [Apis mellifera] NP_001011594.1 2e-61 36% ...

  12. 78 FR 76191 - Operational Tests and Inspections for Compliance With Maximum Authorized Train Speeds and Other...

    Science.gov (United States)

    2013-12-16

    ... also demonstrates the importance of operational testing that pertains to ensuring employee compliance... train, operating in a push-pull configuration (a control cab locomotive is both a passenger car, in that... highlights the need to remain vigilant in ensuring employee compliance with operational speed limits...

  13. Main: ZDNAFORMINGATCAB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ZDNAFORMINGATCAB1 S000321 13-August-2005 (last modified) kehi Z-DNA-forming sequenc...t redundantly to induce Z-box containing promoters in white light; cab1; light; Z-DNA; leaf; shoot; HY5; COP1; LRE; Z-box; ZBF1; Z-box binding factor; Arabidopsis thaliana ATACGTGT ...

  14. Identification and Diagnostics of Entomopathogenic Protozoa

    Czech Academy of Sciences Publication Activity Database

    Oborník, Miroslav

    Wallingford : CAB International, 2009 - (Stock, S.; Vandenberg, J.; Glazer, I.; Boemare, N.), s. 101-128 ISBN 978-1-84593-478-1 Institutional research plan: CEZ:AV0Z60220518 Keywords : entomopathogenic protozoa * diagnostics * strains specific PCR Subject RIV: EB - Genetics ; Molecular Biology

  15. Dimensions of Air Traffic Control Tower Information Needs: From Information Requests to Display Design

    Science.gov (United States)

    Durso, Francis T.; Johnson, Brian R.; Crutchfield, Jerry M.

    2010-01-01

    In an effort to determine the information needs of tower air traffic controllers, instructors from the Federal Aviation Administration's Academy in Oklahoma City were asked to control traffic in a high-fidelity tower cab simulator. Information requests were made apparent by eliminating access to standard tower information sources. Instead,…

  16. Draft Genome Sequence of "Candidatus Methylacidiphilum kamchatkense" Strain Kam1, a Thermoacidophilic Methanotrophic Verrucomicrobium.

    Science.gov (United States)

    Erikstad, Helge-André; Birkeland, Nils-Kåre

    2015-01-01

    "Candidatus Methylacidiphilum kamchatkense" strain Kam1 is an aerobic methane-oxidizing thermoacidophilic bacterium belonging to the Verrucomicrobia phylum. It was recovered from an acidic geothermal site in Uzon Caldera, Kamchatka, Russian Federation. Its genome possesses three complete pmoCAB gene clusters encoding particulate methane monooxygenase enzymes and a complete Calvin-Benson-Bassham cycle for carbon assimilation. PMID:25745002

  17. Draft Genome Sequence of "Candidatus Methylacidiphilum kamchatkense" Strain Kam1, a Thermoacidophilic Methanotrophic Verrucomicrobium.

    OpenAIRE

    Erikstad, Helge Andre; Birkeland, Nils-Kåre

    2015-01-01

    "Candidatus Methylacidiphilum kamchatkense" strain Kam1 is an aerobic methane-oxidizing thermoacidophilic bacterium belonging to the Verrucomicrobia phylum. It was recovered from an acidic geothermal site in Uzon Caldera, Kamchatka, Russian Federation. Its genome possesses three complete pmoCAB gene clusters encoding particulate methane monooxygenase enzymes and a complete Calvin-Benson-Bassham cycle for carbon assimilation.

  18. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Science.gov (United States)

    2010-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  19. Shifting with the Paradigm: LJ's Picks & Pans for ALA in Disneyland

    Science.gov (United States)

    Berry, John N., III

    2008-01-01

    The feelings of librarians planning for the American Library Association (ALA) conference at Disneyland (aka Anaheim, California, June 26-July 2) range from moderate pleasure to dread. Some remember the joys and difficulties of Orlando, especially the exorbitant cab fares and mediocre restaurants. Others quail at screaming kids and tourists in…

  20. Optimized Hyper Beamforming of Linear Antenna Arrays Using Collective Animal Behaviour

    Directory of Open Access Journals (Sweden)

    Gopi Ram

    2013-01-01

    Full Text Available A novel optimization technique which is developed on mimicking the collective animal behaviour (CAB is applied for the optimal design of hyper beamforming of linear antenna arrays. Hyper beamforming is based on sum and difference beam patterns of the array, each raised to the power of a hyperbeam exponent parameter. The optimized hyperbeam is achieved by optimization of current excitation weights and uniform interelement spacing. As compared to conventional hyper beamforming of linear antenna array, real coded genetic algorithm (RGA, particle swarm optimization (PSO, and differential evolution (DE applied to the hyper beam of the same array can achieve reduction in sidelobe level (SLL and same or less first null beam width (FNBW, keeping the same value of hyperbeam exponent. Again, further reductions of sidelobe level (SLL and first null beam width (FNBW have been achieved by the proposed collective animal behaviour (CAB algorithm. CAB finds near global optimal solution unlike RGA, PSO, and DE in the present problem. The above comparative optimization is illustrated through 10-, 14-, and 20-element linear antenna arrays to establish the optimization efficacy of CAB.

  1. Why Include Bibliometric Analysis in the Activities of a Library Specialized in Astronomy? — Notes From the Libraries of INTA

    Science.gov (United States)

    Alonso-Valdivielso, M. Á.; Antonio, E. G.

    2010-10-01

    We describe the different possibilities that several bibliometric studies offer the National Institute of Aerospace Technology (INTA) and the Center for Astrobiology (CAB) libraries. The main object in this paper is to show how the results of these investigations are useful for various matters, such as preservation options, exploitation and diffusion of these results, and facilitating internal information management.

  2. Airports, Hotel, and Ground Transportation Information | Division of Cancer Prevention

    Science.gov (United States)

    Airports in and near Washington, DC Reagan National Approximate 30 minute drive from Rockville* Has its own Metro stop on the blue and yellow lines in Virginia NOTE: This airport may be the closest and easiest option if not renting a car or do not want to pay for an airport cab/shuttle.   Dulles International Approximate 1 hour drive from Rockville* |

  3. Antithrombin III for critically ill patients

    DEFF Research Database (Denmark)

    Allingstrup, Mikkel; Wetterslev, Jørn; Ravn, Frederikke B.;

    2016-01-01

    PURPOSE: Antithrombin III (AT III) is an anticoagulant with anti-inflammatory properties. We assessed the benefits and harms of AT III in critically ill patients. METHODS: We searched from inception to 27 August 2015 in CENTRAL, MEDLINE, EMBASE, CAB, BIOSIS and CINAHL. We included randomized cont...

  4. The Evolution of Light Stress Proteins in Photosynthetic Organisms

    Directory of Open Access Journals (Sweden)

    Iwona Adamska

    2006-04-01

    Full Text Available The Elip (early light-inducible protein family in pro- and eukaryotic photosynthetic organisms consists of more than 100 different stress proteins. These proteins accumulate in photosynthetic membranes in response to light stress and have photoprotective functions. At the amino acid level, members of the Elip family are closely related to light-harvesting chlorophyll a/b-binding (Cab antenna proteins of photosystem I and II, present in higher plants and some algae. Based on their predicted secondary structure, members of the Elip family are divided into three groups: (a one-helix Hlips (high light-induced proteins, also called Scps (small Cab-like proteins or Ohps (one-helix proteins; (b two-helix Seps (stress-enhanced proteins; and (c three-helix Elips and related proteins. Despite having different physiological functions it is believed that eukaryotic three-helix Cab proteins evolved from the prokaryotic Hlips through a series of duplications and fusions. In this review we analyse the occurrence of Elip family members in various photosynthetic prokaryotic and eukaryotic organisms and discuss their evolutionary relationship with Cab proteins.

  5. 49 CFR 238.425 - Electrical system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Electrical system. 238.425 Section 238.425... Equipment § 238.425 Electrical system. (a) Circuit protection. (1) The main propulsion power line shall be.... (b) Main battery system. (1) The main batteries shall be isolated from the cab and passenger...

  6. Behavioral Identification and Assessment of Gifted and Talented Students

    Science.gov (United States)

    Bracken, Bruce A.; Brown, E. F.

    2006-01-01

    Forty-five gifted students and 45 regular education students without identified exceptionalities were rated by teachers and administrators on the Clinical Assessment of Behavior (CAB), a third-party behavior rating scale that rates students' adaptive and behavior problems. The gifted students in this study were rated significantly higher on three…

  7. 49 CFR 230.46 - Badge plates.

    Science.gov (United States)

    2010-10-01

    ... TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Boilers and Appurtenances Steam Gauges § 230.46 Badge plates. A metal badge plate showing the allowed steam pressure shall be attached to the boiler backhead in the cab. If boiler backhead is lagged, the lagging and jacket shall be cut away...

  8. CUL1 Regulates TOC1 Protein Stability in the Arabidopsis Circadian Clock

    Science.gov (United States)

    The circadian clock is the endogenous timer that coordinates physiological processes with daily and seasonal environmental changes. In Arabidopsis thaliana, establishment of the circadian period relies on targeted degradation of TIMING OF CAB EXPRESSION 1 (TOC1) by the 26S proteasome. ZEITLUPE (ZTL)...

  9. 49 CFR 236.531 - Trip arm; height and distance from rail.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Trip arm; height and distance from rail. 236.531... Train Stop, Train Control and Cab Signal Systems Rules and Instructions; Roadway § 236.531 Trip arm; height and distance from rail. Trip arm of automatic train stop device when in the stop position shall...

  10. NCBI nr-aa BLAST: CBRC-STRI-01-2565 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  11. NCBI nr-aa BLAST: CBRC-OPRI-01-0982 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  12. NCBI nr-aa BLAST: CBRC-VPAC-01-1554 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  13. NCBI nr-aa BLAST: CBRC-GGOR-01-1297 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  14. NCBI nr-aa BLAST: CBRC-TTRU-01-0117 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  15. NCBI nr-aa BLAST: CBRC-TSYR-01-1316 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  16. NCBI nr-aa BLAST: CBRC-MDOM-02-0334 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  17. NCBI nr-aa BLAST: CBRC-PVAM-01-1403 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  18. NCBI nr-aa BLAST: CBRC-MLUC-01-1112 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  19. NCBI nr-aa BLAST: CBRC-PHAM-01-1594 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  20. NCBI nr-aa BLAST: CBRC-MMUR-01-1494 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  1. NCBI nr-aa BLAST: CBRC-PCAP-01-1368 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available usculus] emb|CAB42647.1| cannabinoid CB1 receptor [Mus musculus] gb|AAS91800.1| striatal cannabinoid recepto...r type 1 protein [Mus musculus] gb|AAS91801.1| striatal cannabinoid receptor type 1 protein [Mus musculus] g

  2. 49 CFR 238.114 - Rescue access windows.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION PASSENGER EQUIPMENT SAFETY STANDARDS Safety Planning and General Requirements..., electrical locker, or kitchen); and (B) There are no more than eight seats in the seating area. (4) Cars with... bathroom, kitchen, or locomotive cab is not considered a “compartment.” (5) Dual-function windows. If,...

  3. 49 CFR 238.113 - Emergency window exits.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION PASSENGER EQUIPMENT SAFETY STANDARDS Safety Planning and General Requirements..., electrical locker, or kitchen); and (B) There are no more than eight seats in the seating area. (4) Cars with...), a bathroom, kitchen, or locomotive cab is not considered a “compartment.” (b) Ease of...

  4. 49 CFR 236.23 - Aspects and indications.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Aspects and indications. 236.23 Section 236.23...: All Systems Roadway Signals and Cab Signals § 236.23 Aspects and indications. (a) Aspects shall be... conditions: (1) Night aspects of roadway signals, except qualifying appurtenances, shall be shown by...

  5. SNCF experience in anthropometrics

    Science.gov (United States)

    Boutonnet, J. C.

    1986-07-01

    The lecturer describes the methods and the means to design in relation with anthropometrics datas the driving cab of modern SNCF vehicles such as the SYBIC universal locomotive and the TGV-Atlantique power car vehicle is to operate in the end of the decade.

  6. Virginia Tech Bear Researchers Ensure Populations

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The Cooperative Alleghany Bear Study (CABS) was initiated in 1994 as a 10-year study to ensure survival of Virginia's hunted black bear population of western Virginia. During the first six years of the study, researchers have placed radio collars on 376 of the 746 bears captured.

  7. NCBI nr-aa BLAST: CBRC-LAFR-01-0761 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-LAFR-01-0761 ref|NP_593897.1| hypothetical protein SPAC6F6.04c [Schizosaccharomyces... pombe 972h-] emb|CAB11728.1| SPAC6F6.04c [Schizosaccharomyces pombe] NP_593897.1 2.5 29% ...

  8. EST Table: DC547437 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DC547437 E_FL_phe-_10I02_F_0 10/09/28 low homology 10/09/02 low homology 10/08/28 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  9. EST Table: FY015520 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY015520 rbmov14e18 11/11/04 low homology 11/11/04 low homology 11/11/04 46 %/101 aa DY3.1#CE157 ... 45#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  10. EST Table: FS840482 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS840482 E_FL_fner_09K17_F_0 10/09/28 low homology 10/09/10 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  11. EST Table: FS906714 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS906714 E_FL_fufe_09A08_F_0 10/09/28 low homology 10/09/12 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  12. EST Table: BY942076 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BY942076 E_FL_e100_17P17_F_0 10/09/28 low homology 10/08/30 low homology 10/08/28 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  13. EST Table: FS816318 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS816318 E_FL_fmgV_48E11_F_0 10/09/28 low homology 10/09/09 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  14. EST Table: FY018370 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY018370 rbmov22c14 11/11/04 low homology 11/11/04 low homology 11/11/04 46 %/101 aa DY3.1#CE157 ... 45#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  15. EST Table: FS727495 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS727495 E_FL_bmmt_10I12_F_0 10/09/28 low homology 10/09/03 low homology 10/08/28 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  16. EST Table: FS769764 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS769764 E_FL_fcaL_53D03_F_0 10/09/28 low homology 10/09/08 low homology 10/08/28 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  17. EST Table: FS915720 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS915720 E_FL_fufe_36C24_F_0 10/09/28 low homology 10/09/12 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  18. EST Table: FS835316 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS835316 E_FL_fmgV_48E11_R_0 10/09/28 low homology 10/09/10 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  19. EST Table: FS899621 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS899621 E_FL_ftes_35G18_R_0 10/09/28 low homology 10/09/12 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  20. EST Table: FS920114 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS920114 E_FL_fufe_49G13_F_0 10/09/28 low homology 10/09/13 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  1. EST Table: FS917360 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS917360 E_FL_fufe_41C07_F_0 10/09/28 low homology 10/09/12 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  2. EST Table: FS907544 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS907544 E_FL_fufe_11I07_F_0 10/09/28 low homology 10/09/12 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  3. EST Table: FS843600 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS843600 E_FL_fner_18H08_F_0 10/09/28 low homology 10/09/10 low homology 10/08/29 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  4. EST Table: DC545363 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DC545363 E_FL_phe-_02N02_F_0 10/09/28 low homology 10/09/02 low homology 10/08/28 46 %/101 aa DY ... 3.1#CE15745#WBGene00006574#locus:tin - 13#status:Confirmed#UniProt:O45319#protein_id:CAB ...

  5. EST Table: FS920155 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available /09/13 78 %/233 aa FBpp0232921|DvirPros28.1-PA 10/08/29 62 %/212 aa C36B1.4#CE05371#WBGene00003925#locus:pas-4#proteasome A-type subm...it#status:Confirmed#UniProt:Q95005#protein_id:CAB022 69.

  6. EST Table: FS752223 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available /09/08 75 %/224 aa FBpp0232921|DvirPros28.1-PA 10/08/28 58 %/205 aa C36B1.4#CE05371#WBGene00003925#locus:pas-4#proteasome A-type subm...it#status:Confirmed#UniProt:Q95005#protein_id:CAB022 69.

  7. Mathematical applications in radio-chemistry

    International Nuclear Information System (INIS)

    The french little computer CAB 500 has been used to solve some mathematical problems connected with physical measurements in a radiochemical analysis laboratory. Programs have been written for: - standardisation by β - γcoincidences technique, - unfolding of α spectra by a simple method, - extrapolation of β absorption curve by the least squares method, - gross activation, - filiation problems, and so on... (authors)

  8. Hindi Films, Shah Rukh and Kajol Are Hits in Lhasa

    Institute of Scientific and Technical Information of China (English)

    GAUTAMDATT

    2004-01-01

    If you hire a cab in Lhasa don't be surprise if the driver is playing the song from Aamir Khan's award winning film Lagaan. Indian films and music is a hit in Tibet. Nobody understands the language but everybody loves to listen to Indian film songs.

  9. 49 CFR 399.207 - Truck and truck-tractor access requirements.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Truck and truck-tractor access requirements. 399... Vehicles § 399.207 Truck and truck-tractor access requirements. (a) General rule. Any person entering or exiting the cab or accessing the rear portion of a high profile COE truck or truck-tractor shall...

  10. An Economic Evaluation of Voriconazole versus Amphotericin B for the Treatment of Invasive Aspergillosis in Canada

    Directory of Open Access Journals (Sweden)

    Coleman Rotstein

    2004-01-01

    Full Text Available BACKGROUND: Invasive aspergillosis (IA is a serious fungal infection that affects immunocompromised patients. The Global Comparative Aspergillosis study demonstrated that voriconazole, a new broad-spectrum triazole, had better responses and improved survival compared with conventional amphotericin B deoxycholate (CAB and other licensed antifungal therapy (OLAT for the treatment of definite or probable aspergillosis.

  11. NCBI nr-aa BLAST: CBRC-FCAT-01-0809 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-FCAT-01-0809 ref|NP_626507.1| multi-domain regulatory protein [Streptomyces co...elicolor A3(2)] emb|CAB61705.1| putative multi-domain regulatory protein. [Streptomyces coelicolor A3(2)] NP_626507.1 0.017 26% ...

  12. NCBI nr-aa BLAST: CBRC-TGUT-29-0001 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-TGUT-29-0001 ref|NP_626507.1| multi-domain regulatory protein [Streptomyces co...elicolor A3(2)] emb|CAB61705.1| putative multi-domain regulatory protein. [Streptomyces coelicolor A3(2)] NP_626507.1 3e-05 32% ...

  13. NCBI nr-aa BLAST: CBRC-CFAM-20-0010 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CFAM-20-0010 ref|NP_626507.1| multi-domain regulatory protein [Streptomyces co...elicolor A3(2)] emb|CAB61705.1| putative multi-domain regulatory protein. [Streptomyces coelicolor A3(2)] NP_626507.1 9e-10 32% ...

  14. NCBI nr-aa BLAST: CBRC-LAFR-01-1405 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-LAFR-01-1405 ref|NP_627255.1| integral membrane regulatory protein [Streptomyc...es coelicolor A3(2)] emb|CAB88917.1| putative integral membrane regulatory protein [Streptomyces coelicolor A3(2)] NP_627255.1 0.42 32% ...

  15. Unigene BLAST: CBRC-OLAT-24-0017 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-OLAT-24-0017 gnl|UG|Ola#S34478590 AM349219 Oryzias latipes whole embryo Cab stages 18, 24, ... 00006-DPE-R_G18 /gb=AM349219 /gi=112346346 /ug=Ola.12345 ... /len=771 2.5 34% ...

  16. Injuries to occupants in cargo areas of pickup trucks.

    Science.gov (United States)

    Agran, P; Winn, D; Anderson, C

    1994-11-01

    Transporting passengers in the cargo area of pickup trucks is a public health safety issue in the United States. Our study compared crashes involving passengers in the cargo area with those involving passengers in the cab. We obtained data for all injury events of pickup occupants for 1990 from the California Highway Patrol. A total of 702 traffic reports coded as having passengers riding in pickup truck beds involved 1,685 passengers in the cargo area and 865 in the cab. Significantly more events involving passengers in the cargo area occurred in summer in rural areas and were noncollisions than did events with only cab passengers. Crashes with passengers in the cargo area resulted in death in 5% of passengers. Of the drivers, 81% were male and 22% were younger than 20 years. Among the 1,685 passengers in the cargo area, 65% were male, 36% were younger than 15 years, and 30% were ages 15 to 19 years. Passengers in the cargo area were more frequently ejected and more seriously injured than their counterparts in the cab. Legislation to restrict travel in truck beds and the design of restraints for this area are some measures that may reduce the risk of injury. PMID:7810125

  17. Chapter 1. Complex processing of borosilicate ores. 1.1. Properties of borate ores

    International Nuclear Information System (INIS)

    This article is devoted to properties of borate ores, including borax (mineral), boric acid (H3BO3), ulexite (mineral), kernite (mineral), hydrocarbocyte (mineral) Ca Mg(B3O4(OH)3)2·3H2O, datolite (mineral) Ca[B OH(Si-4)], and danburite.

  18. 76 FR 23992 - Meeting To Review and Solicit Input on Tests for Inclusion in the Project 25 Compliance...

    Science.gov (United States)

    2011-04-29

    ... National Institute of Standards and Technology Meeting To Review and Solicit Input on Tests for Inclusion... related to the Program. The scope of a CAB can range from policy to guidance, covering issues such as... conformance tests' suitability for inclusion in the P25 CAP. The following criteria are provided as a...

  19. 49 CFR 236.587 - Departure test.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Departure test. 236.587 Section 236.587..., Train Control and Cab Signal Systems Inspection and Tests; Locomotive § 236.587 Departure test. (a) The...: (1) Operation over track elements; (2) Operation over test circuit; (3) Use of portable...

  20. Destination: New Orleans

    Science.gov (United States)

    Principal, 2009

    2009-01-01

    One can't make the trip to New Orleans for NAESP's Annual Convention and Exposition without checking out a few of the historic and cultural attractions that are within a short walk, or streetcar or cab ride, from the Morial Convention Center and the convention hotels. This article presents a taste of what one can explore between convention events.

  1. 49 CFR 393.201 - Frames.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Frames. 393.201 Section 393.201 Transportation... SAFE OPERATION Frames, Cab and Body Components, Wheels, Steering, and Suspension Systems § 393.201 Frames. (a) The frame or chassis of each commercial motor vehicle shall not be cracked, loose, sagging...

  2. 49 CFR 229.139 - Sanitation, servicing requirements.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Sanitation, servicing requirements. 229.139... Cab Equipment § 229.139 Sanitation, servicing requirements. (a) The sanitation compartment of each... present that prevents waste from evacuating the bowl. (c) The sanitation compartment of each...

  3. 49 CFR 229.137 - Sanitation, general requirements.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Sanitation, general requirements. 229.137 Section... Cab Equipment § 229.137 Sanitation, general requirements. (a) Sanitation compartment. Except as provided in paragraph (b) of this section, all lead locomotives in use shall be equipped with a...

  4. Inhibition of quorum sensing regulated biofilm formation in Serratia marcescens causing nosocomial infections.

    Science.gov (United States)

    Bakkiyaraj, Dhamodharan; Sivasankar, Chandran; Pandian, Shunmugiah Karutha

    2012-05-01

    Serratia marcescens is an opportunistic pathogen causing severe urinary tract infections in hospitalized individuals. Infections of S. marcescens are of great concern because of its increasing resistance towards conventional antibiotics. Quorum sensing (QS)-a cell to cell communication-system of S. marcescens acts as a global regulator of almost all the virulence factors and majorly its biofilm formation. Since, the QS system of S. marcescens directly accords to its pathogenesis, targeting QS system will provide an improved strategy to combat drug resistant pathogens. In the present study, QS system of S. marcescens has been used as target and its inhibition has been studied upon exposure to bioactives from coral associated bacteria (CAB). This study also emphasises the potential of CAB in producing bioactive agents with anti-QS and antibiofilm properties. Two CAB isolates CAB 23 and 41 have shown to inhibit biofilm formation and the production of QS dependent virulence factors like prodigiosin, protease, lipase and swarming motility. The study, on the whole explicates the potential of QS system as a target to treat drug resistant bacterial infections. PMID:22487181

  5. Test Review: Bracken, B. A., & Keith, L. K. (2004). "Clinical Assessment of Behavior." Lutz, FL: Psychological Assessment Resources

    Science.gov (United States)

    Beran, Tanya N.

    2006-01-01

    The Clinical Assessment of Behavior (CAB) is designed to assess both adaptive and problematic behaviors of children and adolescents from age 2 to 18 years. It can be individually or group administered, measures behaviors in different contexts, and includes both parent and teacher forms. The test was developed to be consistent with current…

  6. 49 CFR 236.562 - Minimum rail current required.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Minimum rail current required. 236.562 Section 236..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Automatic Train Stop, Train Control and Cab Signal Systems Rules and Instructions; Locomotives § 236.562...

  7. 49 CFR 236.51 - Track circuit requirements.

    Science.gov (United States)

    2010-10-01

    ..., MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Rules and Instructions..., or cab signal system shall be deenergized in the rear of the point where any of the following conditions exist: (a) When a rail is broken or a rail or switch-frog is removed except when a rail is...

  8. 49 CFR 236.719 - Circuit, acknowledgment.

    Science.gov (United States)

    2010-10-01

    ..., MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.719... track rails at each signal in territory where an automatic train stop system or cab signal system of the... engineman at each signal displaying an aspect requiring a stop....

  9. 49 CFR 236.529 - Roadway element inductor; height and distance from rail.

    Science.gov (United States)

    2010-10-01

    ... rail. 236.529 Section 236.529 Transportation Other Regulations Relating to Transportation (Continued... THE INSTALLATION, INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Automatic Train Stop, Train Control and Cab Signal Systems Rules and...

  10. 14 CFR Sec. 19-7 - Passenger origin-destination survey.

    Science.gov (United States)

    2010-01-01

    ... reporting purposes. The sample shall consist of at least 1 percent of the total lifted ticket flight coupons... Director, Office of Airline Information under the procedures in Sec. 1-2 of 14 CFR part 241. The data to be.... The authority for these instructions is found in 14 CFR part 241, section 19-7, and in the CAB...

  11. Taxonomy, Identification, Genetic Relationships and Distribution of Large Heracleum Species in Europe

    Czech Academy of Sciences Publication Activity Database

    Jahodová, Šárka; Fröberg, L.; Pyšek, Petr; Geltman, D.; Trybush, S.; Karp, A.

    Wallingford : CAB International, 2007 - (Pyšek, P.; Cock, M.; Nentwig, W.; Ravn, H.), s. 1-19 ISBN 978-1-84593-206-0 Grant ostatní: -(XE) EVK2-CT-2001-00128 Institutional research plan: CEZ:AV0Z60050516 Keywords : Heracleum * genetic relationship * distribution Subject RIV: EF - Botanics

  12. Accumulation of the Type IV prepilin triggers degradation of SecY and YidC and inhibits synthesis of Photosystem II proteins in the cyanobacterium Synechocystis PCC 6803

    Czech Academy of Sciences Publication Activity Database

    Linhartová, Markéta; Bučinská, Lenka; Halada, Petr; Ječmen, T.; Šetlík, Jiří; Komenda, Josef; Sobotka, Roman

    2014-01-01

    Roč. 93, č. 6 (2014), s. 1207-1223. ISSN 0950-382X R&D Projects: GA MŠk CZ.2.16/3.1.00/24023; GA ČR GA14-13967S Institutional support: RVO:61388971 Keywords : prepilin * cab-like proteins * Synechocystit Subject RIV: EE - Microbiology, Virology Impact factor: 4.419, year: 2014

  13. Trends in literature on new oilseed crops and related species: Seeking evidence of increasing or waning interest

    Science.gov (United States)

    Bibliographic records on eight new crop species Camelina, Crambe, Cuphea, Physaria, Limnanthes, Stokesia, Thlaspi, and Vernonia from Agricola, CAB Abstracts, Scopus, and Web of Science were analyzed for historical and recent trends in the areas of research, author distribution, and quantity and impa...

  14. "I Always Wanted to Be a Hero." Life without Parole

    Science.gov (United States)

    Roth, Angela M.

    2013-01-01

    In this article, the author recalls her face-to-face meeting with a prison inmate. Paul Jensen is currently serving a life sentence without parole in South Dakota for a crime committed at age 14. In January 1996, Paul was involved in a robbery that went tragically wrong and resulted in the shooting death of taxi cab driver Michael Hare. Three…

  15. Utilization of a Technical Peer Review to Support the Mission of the Nevada Test Site Community Advisory Board

    International Nuclear Information System (INIS)

    The U. S. Department of Energy's (DOE) National Nuclear Security Administration Nevada Operations Office (NNSA/NV) Environmental Management (EM) Underground Test Area (UGTA) project addresses the characterization and needs for long-term monitoring of the subsurface contamination resulting from 828 underground nuclear weapon tests at the Nevada Test Site (NTS). EM promotes, and is required, to include stakeholders in its program. However, UGTA is a very complex program not easily understood by members of the public. The NTS Community Advisory Board (CAB), a federally chartered Site Specific Advisory Board (SSAB), has studied the UGTA project since 1996, and has found it a challenge to completely comprehend and provide NNSA/NV meaningful citizen input. The CAB realized the benefit of a technical peer review and in 2000 recommended to NNSA/NV that a peer review of the UGTA strategy would provide valuable feedback to the program to address underground contamination at the NTS. N NSA agreed to the CAB's recommendation, and moved forward with a scope of work to have the American Society of Mechanical Engineers (ASME) perform the peer review of the UGTA strategy. The ASME began the peer review in June 2001, and their final report was published in November 2001. In January 2002, the CAB devoted their monthly meeting in Las Vegas, Nevada to reporting the results of the peer review of the UGTA strategy to the public. Two public workshops were later held in the community of Amargosa, Nevada during the month of January to help educate and build interest in the CAB February 2002 monthly meeting which was also held in Amargosa. The CAB recommendation to NNSA to utilize a technical peer review has provided valuable information to NNSA, the State of Nevada, and the CAB. At other DOE sites SSABs are challenged by a number of complex, technical programs requiring considerable time and resources for the board to comprehend. It is worth considering the utilization of an independent

  16. A Spatiotemporal Analysis on the Correlation of Leaf Chlorophyll With Light-use-efficiencies Across a Heterogeneous Corn Field

    Science.gov (United States)

    Houborg, R.; Anderson, M. C.; Kustas, W. P.; Daughtry, C.

    2009-05-01

    Chlorophylls absorb photosynthetically active radiation and thus function as vital pigments for photosynthesis, which makes leaf chlorophyll content (Cab) useful for monitoring vegetation productivity and an important indicator of the overall plant physiological condition. This study investigates the utility of spatiotemporal Cab estimates for optimizing CO2 fluxes simulated by a coupled water and carbon cycle model that implements an analytical, light-use-efficiency (LUE) based model of canopy resistance within a two-source energy balance scheme. The LUE model component computes canopy-scale carbon assimilation and transpiration fluxes and incorporates LUE modifications from a nominal value (LUEn) in response to variations in humidity, CO2 concentration, temperature (soil and air), wind speed, and direct beam vs. diffuse light composition. LUEn is typically indexed by vegetation class assuming conservation of LUE for major vegetation types under unstressed environmental conditions. LUEn is highly influential in modifying CO2 assimilation rates and may need further adjustment on a daily timescale to accommodate changes in plant phenology, physiological condition and nutrient status. Day to day variations in LUEn was assessed for a heterogeneous corn crop field in Maryland, U.S.A. through model calibration with eddy covariance CO2 flux tower observations. The optimized daily LUEn values were then compared to estimates of Cab integrated from gridded Cab maps as a weighted sum over the tower flux source area. A continuous spatiotemporal Cab record (spanning the period from 3 weeks after leaf emergence through corn tasseling and silking and a stage of leaf senescence) was generated by fusing extensive in-situ measurements with retrievals generated from 1 m resolution aircraft imagery using an integrated radiative transfer modeling tool (validated to 10% accuracy). Extreme environmental conditions imposed highly variable degrees of plant stress across the field due to

  17. Estudio retrospectivo sobre las posibles complicaciones maternofetales de la exposición a cabergolina Retrospective Study of any potencial Adverse Effects of Cabergoline on Pregnancy and Embryofetal Development

    Directory of Open Access Journals (Sweden)

    G. Stalldecker

    2010-09-01

    Full Text Available Objetivos: Estimar la frecuencia de complicaciones maternofetales en mujeres que se embarazaron durante el tratamiento con cabergolina (CAB. Estimar la frecuencia de patología detectada posnacimiento en los niños producto de dichos embarazos. Material y métodos: Estudio retrospectivo y multicéntrico de 86 embarazos en 78 mujeres con hiperprolactinemia idiopática (7 o tumoral (44 micro y 27 macro, en tratamiento con CAB en el momento de la concepción. Edad: 20 a 45 años; PRL inicial: 30 a 1429 ng/ml; duración del tratamiento previo al embarazo 1 a 120 meses; dosis: 0.125 a 4 mg/semana. El rango de exposición embriofetal a la CAB fue de 3 a 27 semanas, el 96.39% de las pacientes la recibió durante el primer trimestre y el 3.61% hasta el segundo. Resultados: No hubo complicaciones mayores durante el embarazo. Se registraron 7 abortos espontáneos (8.1% y 75 partos, de los cuales 49 fueron vaginales y 26 cesáreas. Se registraron 69 recién nacidos, 63 fueron a término y 6 pretérmino (8.8%, ninguno bajo peso para la edad gestacional. En 3 (5.2% recién nacidos se observó: 1 malformación mayor (Síndrome de Down y 2 menores (hernia umbilical e inguinal. Se obtuvo seguimiento de 42 recién nacidos; se diagnosticó epilepsia refractaria en uno y un trastorno generalizado del desarrollo en otro. No se halló una mayor frecuencia de complicaciones en los embarazos ni en los recién nacidos expuestos a CAB que en la población normal. Sería necesario mayor número de pacientes para concluir sobre la seguridad de CAB durante el embarazo.Objectives: To assess the rate of any potential adverse effects on pregnancy and embryo-fetal development in women who became pregnant under treatment with cabergoline (CAB. To follow up medical data of children who were born from mothers exposed to Cab in early weeks of gestation. Material and methods: Observational, retrospective and multicenter study on 86 pregnancies in 78 women with idiopathic or tumoral

  18. APPLICATION OF CHEMICALLY ACCELERATED BIOTREATMENT TO REDUCE RISKIN OIL-IMPACTED SOILS

    Energy Technology Data Exchange (ETDEWEB)

    J.R. Paterek; W.W.Bogan; V. Trbovic; W. Sullivan

    2003-01-07

    The drilling and operation of gas/petroleum exploratory wells and the operations of natural gas and petroleum production wells generate a number of waste materials that are usually stored and/or processed at the drilling/operations site. Contaminated soils result from drilling operations, production operations, and pipeline breaks or leaks where crude oil and petroleum products are released into the surrounding soil or sediments. In many cases, intrinsic biochemical remediation of these contaminated soils is either not effective or is too slow to be an acceptable approach. This project targeted petroleum-impacted soil and other wastes, such as soil contaminated by: accidental release of petroleum and natural gas-associated organic wastes from pipelines or during transport of crude oil or natural gas; production wastes (such as produced waters, and/or fuels or product gas). Our research evaluated the process designated Chemically-Accelerated Biotreatment (CAB) that can be applied to remediate contaminated matrices, either on-site or in situ. The Gas Technology Institute (GTI) had previously developed a form of CAB for the remediation of hydrocarbons and metals at Manufactured Gas Plant (MGP) sites and this research project expanded its application into Exploration and Production (E&P) sites. The CAB treatment was developed in this project using risk-based endpoints, a.k.a. environmentally acceptable endpoints (EAE) as the treatment goal. This goal was evaluated, compared, and correlated to traditional analytical methods (Gas Chromatography (GC), High Precision Liquid Chromatography (HPLC), or Gas Chromatography-Mass Spectrometry (CGMS)). This project proved that CAB can be applied to remediate E&P contaminated soils to EAE, i.e. those concentrations of chemical contaminants in soil below which there is no adverse affect to human health or the environment. Conventional approaches to risk assessment to determine ''how clean is clean'' for soils

  19. DEMOLISHING A COLD-WAR-ERA FUEL-STORAGE BASIN SUPERSTRUCTURE LADEN WITH ASBESTOS

    International Nuclear Information System (INIS)

    The K East (KE) Basin facilities are located near the north end of the Hanford Site's 100 K area. The facilities were built in 1950 as part of the KE Reactor complex and constructed within 400 meters of the Columbia River, which is the largest river in the Pacific Northwest and by volume the fourth largest river in the United States. The basin, located adjacent to the reactor, was used for the underwater storage of irradiated nuclear fuel discharged from the reactor. The basin was covered by a superstructure comprising steel columns and beams, concrete, and cement asbestos board (CAB) siding. The project's mission was to complete demolition of the structure over the K East basin within six months of tumover from facility deactivation activities. The demolition project team implemented open-air demolition techniques to demolish the facility to slab-on-grade. Several innovative techniques were used to control contamination and maintain contamination control within the confines of the demolition exclusion zone. The techniques, which focused on a defense-in-depth approach, included spraying fixatives on interior and exterior surfaces before demolition began; applying fixatives; misting using a fine spray of water during demolition; and demolishing the facility systematically. Another innovation that aided demolition was to demolish the building with the non-friable CAB remaining in place. The CAB siding covered the exterior of the building, portions of the interior walls, and was an integral part of the multiple layered roof. The project evaluated the risks involved in removing the CAB material in a radiologically contaminated environment and determined that radiological dose rates and exposure to radiological contamination and industrial hazards would be significantly reduced by removing the CAB during demolition using heavy equipment. The ability to perform this demolition safely and without spreading contamination (radiological or asbestos) demonstrates that similar

  20. DEMOLISHING A COLD-WAR-ERA FUEL STORAGE BASIN SUPERSTRUCTURE LADEN WITH ASBESTOS

    Energy Technology Data Exchange (ETDEWEB)

    LLOYD ER; ORGILL TK; DAGAN EB

    2008-11-25

    The K East (KE) Basin facilities are located near the north end of the Hanford Site's 100 K area. The facilities were built in 1950 as part of the KE Reactor complex and constructed within 400 meters of the Columbia River, which is the largest river in the Pacific Northwest and by volume the fourth largest river in the United States. The basin, located adjacent to the reactor, was used for the underwater storage of irradiated nuclear fuel discharged from the reactor. The basin was covered by a superstructure comprising steel columns and beams, concrete, and cement asbestos board (CAB) siding. The project's mission was to complete demolition of the structure over the K East basin within six months of tumover from facility deactivation activities. The demolition project team implemented open-air demolition techniques to demolish the facility to slab-on-grade. Several innovative techniques were used to control contamination and maintain contamination control within the confines of the demolition exclusion zone. The techniques, which focused on a defense-in-depth approach, included spraying fixatives on interior and exterior surfaces before demolition began; applying fixatives; misting using a fine spray of water during demolition; and demolishing the facility systematically. Another innovation that aided demolition was to demolish the building with the non-friable CAB remaining in place. The CAB siding covered the exterior of the building, portions of the interior walls, and was an integral part of the multiple layered roof. The project evaluated the risks involved in removing the CAB material in a radiologically contaminated environment and determined that radiological dose rates and exposure to radiological contamination and industrial hazards would be significantly reduced by removing the CAB during demolition using heavy equipment. The ability to perform this demolition safely and without spreading contamination (radiological or asbestos) demonstrates

  1. DEMOLISHING A COLD-WAR-ERA FULE-STORAGE BASIN SUPERSTRUCTURE LADEN WITH ASBESTOS

    International Nuclear Information System (INIS)

    The K East (KE) Basin facilities are located near the north end of the Hanford Site's 100 K area. The facilities were built in 1950 as part of the KE Reactor complex and constructed within 400 meters of the Columbia River, which is the largest river in the Pacific Northwest and by volume the fourth largest river in the United States. The basin, located adjacent to the reactor, was used for the underwater storage of irradiated nuclear fuel discharged from the reactor. The basin was covered by a superstructure comprising steel columns and beams, concrete, and cement asbestos board (CAB) siding. The project's mission was to complete demolition of the structure over the KE Basin within six months of turnover from facility deactivation activities. The demolition project team applied open-air demolition techniques to bring the facility to slab-on-grade. Several innovative techniques were used to control contamination and maintain contamination control within the confines of the demolition exclusion zone. The techniques, which focused on a defense-in-depth approach, included spraying fixatives on interior and exterior surfaces before demolition began; applying fixatives during the demolition; misting using a fine spray of water during demolition; and demolishing the facility systematically. Another innovative approach that made demolition easier was to demolish the building with the non-friable CAB remaining in place. The CAB siding covered the exterior of the building and portions of the interior walls, and was an integral part of the multiple-layered roof. The project evaluated the risks involved in removing the CAB material in a radiologically contaminated environment and determined that radiological dose rates and exposure to radiological contamination and industrial hazards would be significantly reduced by using heavy equipment to remove the CAB during demolition. The ability to perform this demolition safely and without spreading contamination (radiological or

  2. DEMOLISHING A COLD WARE ERA FULE STORAGE BASIN SUPERSTRUCTURE LADEN WITH ASBESTOS

    Energy Technology Data Exchange (ETDEWEB)

    LLOYD ER; STEVENS JM; DAGAN EB; ORGILL TK; GREEN MA; LARSON CH; ZINSLI LC

    2009-01-12

    The K East (KE) Basin facilities are located near the north end of the Hanford Site's 100 K area. The facilities were built in 1950 as part of the KE Reactor complex and constructed within 400 meters of the Columbia River, which is the largest river in the Pacific Northwest and by volume the fourth largest river in the United States. The basin, located adjacent to the reactor, was used for the underwater storage of irradiated nuclear fuel discharged from the reactor. The basin was covered by a superstructure comprising steel columns and beams, concrete, and cement asbestos board (CAB) siding. The project's mission was to complete demolition of the structure over the KE Basin within six months of turnover from facility deactivation activities. The demolition project team applied open-air demolition techniques to bring the facility to slab-on-grade. Several innovative techniques were used to control contamination and maintain contamination control within the confines of the demolition exclusion zone. The techniques, which focused on a defense-in-depth approach, included spraying fixatives on interior and exterior surfaces before demolition began; applying fixatives during the demolition; misting using a fine spray of water during demolition; and demolishing the facility systematically. Another innovative approach that made demolition easier was to demolish the building with the non-friable CAB remaining in place. The CAB siding covered the exterior of the building and portions of the interior walls, and was an integral part of the multiple-layered roof. The project evaluated the risks involved in removing the CAB material in a radiologically contaminated environment and determined that radiological dose rates and exposure to radiological contamination and industrial hazards would be significantly reduced by using heavy equipment to remove the CAB during demolition. The ability to perform this demolition safely and without spreading contamination

  3. Investigation on the long-term stability of IRMM-1027 series of Large-Sized Dried (LSD) spikes

    International Nuclear Information System (INIS)

    The IRMM-1027 is a certified reference material for nuclear material control and accountancy. Each individual spike contains about 50 mg uranium (m(235U)/m(U) ∼ 20%) and about 1.8 mg plutonium (m(239Pu)/m(Pu) ∼ 98%) in dried form. They are used for the determination of U and Pu content of spent fuel solutions with isotope dilution mass spectrometry (IDMS) by plant operators and safeguards authorities. The dried uranyl and plutonium nitrates are embedded in an organic substance, which provides a stable layer at the bottom of the vial and preserves the integrity of the spike during storage and transport. Cellulose acetate butyrate (CAB) with 19 wt% butyryl content has been applied on the IRMM-1027 spikes for the last decade. However, the cellulose matrix containing the spike material tends to flake off after about two years. In order to prolong the shelf life of the spikes, JRC-IRMM has been investigating CABs with higher butyryl contents – 35 wt% and 52 wt% –, to optimize the chemical stability and to achieve a longer lasting layer. Empirical tests have shown that the higher the butyryl content, chemically the more stable and the more resistant the CAB is. Accordingly, future series of LSD spikes will be prepared with CAB containing 35 wt% butyryl, which should remain intact for at least 4 years. Furthermore, JRC-IRMM together with CPMT is investigating the chemical and mechanical properties of the three different CABs to further improve understanding on their stability and durability.

  4. Mechanical Demolition of Buildings with Concrete Asbestos Board Siding: Methodology, Precautions, and Results at the Hanford Central Plateau - 12417

    Energy Technology Data Exchange (ETDEWEB)

    Kehler, Kurt [Decommissioning and Demolition, CH2M HILL Plateau Remediation Company, Richland, Washington (United States)

    2012-07-01

    Since the start of its contract in 2008, the CH2M Hill Plateau Remediation Company (CH2M HILL) has demolished 25 buildings with concrete asbestos board (CAB) siding using mechanical means. While the asbestos contained in CAB siding is not friable in its manufactured form, concerns persist that mechanical methods of demolition have the potential to render the asbestos friable and airborne, therefore posing a health risk to demolition workers and the public. CH2M HILL's experience demonstrates that when carefully managed, mechanical demolition of CAB siding can be undertaken safely, successfully, and in compliance with regulatory requirements for the disposal of Class II Asbestos-Containing Material (ACM). While the number of buildings demolished at Hanford and the number of samples collected does not make a conclusive argument that CAB cannot be made friable with normal demolition techniques, it certainly provides a significant body of evidence for the success of the approach. Of course, there are many factors that affect how to demolish a structure and dispose of the waste. These factors will impact the success depending on each site. The most obvious factors which contribute to this success at Hanford are: 1. The availability of onsite waste disposal where the handling and cost of asbestos-containing waste is not much different than other potentially contaminated waste. Therefore, segregation of demolition debris from the potential asbestos contamination is not necessary from a debris handling or asbestos disposal aspect. 2. The space between structures is typically significant enough to allow for large exclusion zones. There are not many restrictions due to cohabitation issues or potential contamination of adjacent facilities. 3. The willingness of the regulators and client to understand the industrial safety issues associated with manual CAB removal. (authors)

  5. Mechanical Demolition of Buildings with Concrete Asbestos Board Siding: Methodology, Precautions, and Results at the Hanford Central Plateau - 12417

    International Nuclear Information System (INIS)

    Since the start of its contract in 2008, the CH2M Hill Plateau Remediation Company (CH2M HILL) has demolished 25 buildings with concrete asbestos board (CAB) siding using mechanical means. While the asbestos contained in CAB siding is not friable in its manufactured form, concerns persist that mechanical methods of demolition have the potential to render the asbestos friable and airborne, therefore posing a health risk to demolition workers and the public. CH2M HILL's experience demonstrates that when carefully managed, mechanical demolition of CAB siding can be undertaken safely, successfully, and in compliance with regulatory requirements for the disposal of Class II Asbestos-Containing Material (ACM). While the number of buildings demolished at Hanford and the number of samples collected does not make a conclusive argument that CAB cannot be made friable with normal demolition techniques, it certainly provides a significant body of evidence for the success of the approach. Of course, there are many factors that affect how to demolish a structure and dispose of the waste. These factors will impact the success depending on each site. The most obvious factors which contribute to this success at Hanford are: 1. The availability of onsite waste disposal where the handling and cost of asbestos-containing waste is not much different than other potentially contaminated waste. Therefore, segregation of demolition debris from the potential asbestos contamination is not necessary from a debris handling or asbestos disposal aspect. 2. The space between structures is typically significant enough to allow for large exclusion zones. There are not many restrictions due to cohabitation issues or potential contamination of adjacent facilities. 3. The willingness of the regulators and client to understand the industrial safety issues associated with manual CAB removal. (authors)

  6. HFC-152a and HFC-134a emission estimates and characterization of CFCs, CFC replacements, and other halogenated solvents measured during the 2008 ARCTAS campaign (CARB phase over the South Coast Air Basin of California

    Directory of Open Access Journals (Sweden)

    B. Barletta

    2011-03-01

    Full Text Available This work presents results from the NASA Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS study. Whole air samples were obtained on board research flights that flew over California during June 2008 and analyzed for selected volatile organic compounds, including several halogenated species. Samples collected over the South Coast Air Basin of California (SoCAB, which includes much of Los Angeles (LA County, were compared with samples from inflow air masses over the Pacific Ocean. The levels of many halocarbon species were enhanced significantly over the SoCAB, including compounds regulated by the Montreal Protocol and subsequent amendments. Emissions estimates of HFC-152a (1,1-difluoroethane, CH3CHF2; 0.82 ± 0.11 Gg and HFC-134a (1,1,1,2-tetrafluoroethane, CH2FCF3; 1.16 ± 0.22 Gg in LA County for 2008 were obtained using the observed HFC:carbon monoxide (CO enhancement ratio. Emission rates also were calculated for the SoCAB (1.60 ± 0.22 Gg yr−1 for HFC-152a and 2.12 ± 0.28 Gg yr−1 for HFC-134a and then extrapolated to the United States (32 ± 4 Gg yr−1 for HFC-152a and 43 ± 6 Gg yr−1 for HFC-134a using population data. In addition, emission rates of the two HFCs in LA County and SoCAB were calculated by a second method that utilizes air quality modeling. Emissions estimates obtained using both methods differ by less than 25% for the LA County and less than 45% for the SoCAB.

  7. HFC-152a and HFC-134a emission estimates and characterization of CFCs, CFC replacements, and other halogenated solvents measured during the 2008 ARCTAS campaign (CARB phase) over the South Coast Air Basin of California

    Science.gov (United States)

    Barletta, B.; Nissenson, P.; Meinardi, S.; Dabdub, D.; Sherwood Rowland, F.; Vancuren, R. A.; Pederson, J.; Diskin, G. S.; Blake, D. R.

    2011-03-01

    This work presents results from the NASA Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) study. Whole air samples were obtained on board research flights that flew over California during June 2008 and analyzed for selected volatile organic compounds, including several halogenated species. Samples collected over the South Coast Air Basin of California (SoCAB), which includes much of Los Angeles (LA) County, were compared with samples from inflow air masses over the Pacific Ocean. The levels of many halocarbon species were enhanced significantly over the SoCAB, including compounds regulated by the Montreal Protocol and subsequent amendments. Emissions estimates of HFC-152a (1,1-difluoroethane, CH3CHF2; 0.82 ± 0.11 Gg) and HFC-134a (1,1,1,2-tetrafluoroethane, CH2FCF3; 1.16 ± 0.22 Gg) in LA County for 2008 were obtained using the observed HFC:carbon monoxide (CO) enhancement ratio. Emission rates also were calculated for the SoCAB (1.60 ± 0.22 Gg yr-1 for HFC-152a and 2.12 ± 0.28 Gg yr-1 for HFC-134a) and then extrapolated to the United States (32 ± 4 Gg yr-1 for HFC-152a and 43 ± 6 Gg yr-1 for HFC-134a) using population data. In addition, emission rates of the two HFCs in LA County and SoCAB were calculated by a second method that utilizes air quality modeling. Emissions estimates obtained using both methods differ by less than 25% for the LA County and less than 45% for the SoCAB.

  8. 7-Chloroarctinone-b as a new selective PPARγ antagonist potently blocks adipocyte differentiation

    Institute of Scientific and Technical Information of China (English)

    Yong-tao LI; Li LI; Jing CHEN; Tian-cen HU; Jin HUANG; Yue-wei GUO; Hua-liang JIANG; Xu SHEN

    2009-01-01

    Aim: Peroxisome proliferator-activated receptor gamma (PPARy) is a therapeutic target for obesity, cancer and diabetes mellitus. In order to develop potent lead compounds for obesity treatment, we screened a natural product library for novel PPARy antagonists with inhibitory effects on adipocyte differentiation. Methods: Surface plasmon resonance (SPR) technology and cell-based transactivation assay were used to screen for PPARy antago-nists. To investigate the antagonistic mechanism of the active compound, we measured its effect on PPARy/RXRα heterodimerization and PPARy co-activator recruitment using yeast two-hybrid assay, Gal4/UAS cell-based assay and SPR based assay. The 3T3-L1 cell differentiation assay was used to evaluate the effect of the active compound on adipocyte differentiation. Results: A new thiophene-acetylene type of natural product, 7-chloroarctinone-b (CAB), isolated from the roots of Rhaponticum uniflo-rum, was discovered as a novel PPARγ antagonist capable of inhibiting rosiglitazone-induced PPARγ transcriptional activity. SPR analy-sis suggested that CAB bound tightly to PPARγ and considerably antagonized the potent PPARy agonist rosigtitazone-stimulated PPARγ-LBD/RXRα-LBD binding. Gal4/UAS and yeast two-hybrid assays were used to evaluate the antagonistic activity of CAB on rosiglitazone-induced recruitment of the coactivator for PPARy. CAB could efficiently antagonize both hormone and rosiglitazone-induced adipocyte differentiation in cell culture. Conclusion: CAB shows antagonistic activity to PPARγ and can block the adipocyte differentiation, indicating it may be of potential use as a lead therapeutic compound for obesity.

  9. Electronic structures, mechanical and thermodynamic properties of cubic alkaline-earth hexaborides from first principles calculations

    International Nuclear Information System (INIS)

    Highlights: • The band gaps for CaB6, SrB6 and BaB6 depend sensitively on the values of lattice constant a and positional parameter z. • The order in elastic anisotropy is CaB6 > SrB6 > BaB6. • There are LO/TO splitting lines in the range of 5–10 THz at G point. - Abstract: The electronic structures, mechanical and thermodynamic properties of alkaline-earth hexaborides MB6 (M = Ca, Sr or Ba) are calculated from first principles using density functional theory combined with the quasi-harmonic approximation. These three alkaline-earth hexaborides are semiconductors with a slightly increased trend for their band gaps as M orders from Ca to Ba. Their band gaps depend sensitively on the values of lattice constant a and internal parameter z. The polycrystalline values of the elastic constants and bulk, shear and Young’s moduli are consistent with those determined experimentally. All alkaline-earth hexaborides have strongly anisotropic elastic properties in the order of CaB6 > SrB6 > BaB6. By using the phonon calculations, the thermodynamic properties are investigated. The obtained phonon dispersion relations for CaB6, SrB6, and BaB6 show similar features and there are LO/TO splitting lines in the range of 5–10 THz. Finally, the thermal conductivities of CaB6, SrB6 and BaB6 are evaluated via Clarke’s model and Cahill’s model

  10. Factors relating to the development of respiratory symptoms in coffee process workers.

    Science.gov (United States)

    Thomas, K E; Trigg, C J; Baxter, P J; Topping, M; Lacey, J; Crook, B; Whitehead, P; Bennett, J B; Davies, R J

    1991-05-01

    After several cases of occupational asthma had been reported in a coffee processing factory in England, 197 coffee workers representing 80% of the production workforce were studied to determine the factors affecting the development of work related respiratory symptoms of wheeze, cough, and dyspnoea. Two computer administered questionnaires concerning the presence of respiratory symptoms and the occurrence of work related respiratory symptoms were used. Workers underwent skin prick testing to green coffee bean extract (GCB) and 11 common inhalant allergen extracts and bronchial provocation testing with methacholine. The presence of specific immunoglobulin E (IgE) antibodies to GCB and castor bean extract (CAB) were determined by a radioallergosorbent test (RAST). The prevalence of work related respiratory symptoms was 12.7%, bronchial hyperresponsiveness 30%, atopy 54%, positive GCB skin prick test 14.7%, positive GCB RAST 14%, and positive CAB RAST 14.7%. None of the workers was sensitised to fungi present in the factory and the numbers of certain species of fungi, despite being greater than may be found out of doors or in an uncontaminated indoor environment, were fewer than are generally associated with the presence of work related respiratory symptoms among agricultural workers. Storage mites were not isolated. Green coffee bean extract and CAB RAST were significantly correlated using the McNemar test but there was limited allergenic cross reactivity in RAST inhibition studies of the two extracts. The only factors that were significantly and independently associated with work related symptoms were CAB RAST and duration of employment. Bronchial hyperresponsiveness was not independently associated with work related respiratory symptoms. The significant independent associations of bronchial hyperresponsiveness included GCB RAST, duration of employment, and resting forced expiratory volume in one second. Exposure to CAB, a highly potent antigen, may be overriding

  11. Rapid, controllable and environmentally benign fabrication of thermoplastic nanofibers and applications

    Science.gov (United States)

    Wang, Dong

    In situ fibrillar and lamellar hybrid morphology was found in various immiscible polymer blends prepared by melt ram extrusion of cellulose acetate butyrate (CAB)/Thermoplastics at a weight ratio of 80 to 20. The formation process was analyzed and proposed. The presence of the elongational flow field determines the formation of the fibrils, and the improvement of the mixing efficiency can significantly reduce the dimensions of formed fibrils into the submicro- or nano-scale. With above results, continuous and uniform yarns of thermoplastic nanofibers were prepared via direct melt twin-screw extrusion, providing better mixing efficiency of immiscible blends of thermoplastic polymers with cellulose acetate butyrate (CAB), and subsequent extraction removal of CAB matrix. The thermoplastics which can be made into nanofibers include polyesters, polyolefins, thermoplastic polyurethane and functional copolymers, such as PE-co-GMA (Poly(Ethylene-co-Glycidyl Methacrylate)), PVA-co-PE (Poly(Vinyl Alcohol-co-Ethylene)). Ratios of thermoplastics to sacrificial CAB matrix, melt viscosity, and interfacial tensions affect formation of the nanofibers. Moreover, the crystal structures of isotactic polypropylene (iPP) nanofiber prepared were characterized with DSC and WAXD. To further demonstrate the size and shape controllability of the thermoplastic nanomaterials, polyethylene materials were selected and prepared into micro- or submicrospheres or nanofibers with different diameters and shapes by varying the composition ratio and modifying the interface properties via melt blending or extrusion of cellulose acetate butyrate (CAB)/LDPE melt blends and subsequent removal of the CAB. The surface structures of the LDPE micro- or submicrospheres and nanofibers were analyzed using SEM, FTIR-ATR spectroscopy, DSC and torque rheometer. The biotechnological applications of the thermoplastic nanofibers are also exploited. Poly(ethylene-co-glycidyl methacrylate) (PE-co-GMA) nanofibers with

  12. Suplemento múltiplo com ionóforos para novilhos em pasto: consumo, fermentação ruminal e degradabilidade in situ

    OpenAIRE

    M.H.F. Mourthe; R.B. Reis; M.M. Ladeira; R.C. Souza; S.G. Coelho; H.M. Saturnino

    2011-01-01

    Avaliou-se o efeito do suplemento múltiplo com ionóforos sobre o consumo, a fermentação ruminal e a degradabilidade in situ da matéria seca da forragem. Utilizaram-se cinco novilhos Holandês x Zebu fistulados no rúmen, com peso vivo médio de 350kg, em delineamento em quadrado latino. Os tratamentos foram: suplementação múltipla sem ionóforos (CONT); suplementação múltipla com 100mg/cab/dia de monensina (M100); suplementação múltipla com 200mg/cab/dia de monensina (M200); suplementação múltipl...

  13. Study of the characterization and formulation of the decontamination gels

    International Nuclear Information System (INIS)

    To develop a chemical gel decontamination technology for a removal of non-fixed contaminants during the maintenance and decommissioning works of high radiation hot cells which have been used for a recycling or treatment of spent fuels we have prepare gels with CAB-O-SIL M-5 or Aerosil 380 as viscosifier and some non-ionic surfactants such as diethylene glycol hexyl ether, triethylene glycol dodecyl ether, polyethylene glycol 600, and triethylene glycol butyl ether. Surfactants are playing important roles in manipulating the properties of decontamination the gels. We have found the CAB-O-SIL with triethylene glycol butyl ether and Aerosil with triethylene glycol dodecyl ether systems promising for the decontamination work

  14. Combining Coarse-Grained Protein Models with Replica-Exchange All-Atom Molecular Dynamics

    Directory of Open Access Journals (Sweden)

    Andrzej Koliński

    2013-05-01

    Full Text Available We describe a combination of all-atom simulations with CABS, a well-established coarse-grained protein modeling tool, into a single multiscale protocol. The simulation method has been tested on the C-terminal beta hairpin of protein G, a model system of protein folding. After reconstructing atomistic details, conformations derived from the CABS simulation were subjected to replica-exchange molecular dynamics simulations with OPLS-AA and AMBER99sb force fields in explicit solvent. Such a combination accelerates system convergence several times in comparison with all-atom simulations starting from the extended chain conformation, demonstrated by the analysis of melting curves, the number of native-like conformations as a function of time and secondary structure propagation. The results strongly suggest that the proposed multiscale method could be an efficient and accurate tool for high-resolution studies of protein folding dynamics in larger systems.

  15. KINETICS OF OXIDATION OF SALBUTAMOL BY CHLORAMINE-B IN NaOH MEDIUM: A MECHANISTIC APPROACH

    Directory of Open Access Journals (Sweden)

    Iyengar Pushpa

    2012-04-01

    Full Text Available The kinetics of oxidation of salbutamol (SBL by N-chlorobenzenesulphonamide (CAB in NaOH medium has been investigated at 303K. The reaction rate shows a first order dependence on [CAB]0 , fractional order with respect to [SBL]0 and a negative fractional order with respect to [OH-] . The addition of the reduction product, benzenesulphonamide , retards the reaction rate. The effect of dielectric constant of the medium by varying [MeOH] shows an inverse effect. The addition of chloride ions and variation of ionic strength of the medium have no significant effect on the rate of the reaction. The reaction fails to initiate polymerization of acrylamide. The oxidation products were identified. The Michaelis – Menten type of kinetics has been proposed. The reaction was studied at different temperatures and the values of thermodynamic parameters were computed. A mechanism consistent with the observed kinetics is proposed.

  16. Human calumenin localizes to the secretory pathway and is secreted to the medium

    DEFF Research Database (Denmark)

    Vorum, H; Hager, H; Christensen, Birgitte Mønster; Nielsen, Søren; Honoré, B

    1999-01-01

    Calumenin belongs to a family of multiple EF-hand proteins that include reticulocalbin, ERC-55, and Cab45. Reticulocalbin and ERC-55 localize to the ER due to a C-terminal HDEL retrieval signal. Cab45 contains a HEEF C-terminal sequence and is localized to the Golgi apparatus. The murine homologue...... of calumenin is reported to be present in the ER due to a C-terminal HDEF retrieval signal. The human homologue differs from the murine at 7 amino acid positions but the HDEF signal is conserved. However, in the cultured human cell lines, HaCaT keratinocytes, normal and transformed MRC-5 fibroblasts......, as well as in transfected COS-1 cells, human calumenin could be demonstrated in the ER as well as in the Golgi complex. Especially in MRC-5 cells, a certain heterogeneity was observed, with some of the cells having calumenin localized solely to the ER while in other cells calumenin could be...

  17. Combining Coarse-Grained Protein Models with Replica-Exchange All-Atom Molecular Dynamics

    CERN Document Server

    Wabik, Jacek; Gront, Dominik; Kouza, Maksim; Kolinski, Andrzej

    2013-01-01

    We describe a combination of all-atom simulations with CABS, a well-established coarse-grained protein modeling tool, into a single multiscale protocol. The simulation method has been tested on the C-terminal beta hairpin of protein G, a model system of protein folding. After reconstructing atomistic details, conformations derived from the CABS simulation were subjected to replica-exchange molecular dynamics simulations with OPLS-AA and AMBER99sb force fields in explicit solvent. Such a combination accelerates system convergence several times in comparison with all-atom simulations starting from the extended chain conformation, demonstrated by the analysis of melting curves, the number of native-like conformations as a function of time and secondary structure propagation. The results strongly suggest that the proposed multiscale method could be an efficient and accurate tool for high-resolution studies of protein folding dynamics in larger systems.

  18. Analytical and experimental assessment of heavy truck ride

    Energy Technology Data Exchange (ETDEWEB)

    Field, R.V. Jr.; Hurtado, J.E.; Carne, T.G.

    1997-12-01

    This study is the second phase in a combined analytical and experimental effort to characterize and improve the ride quality of the Department of Energy tractor/trailer. The discussion includes a brief overview of the finite element model of the vehicle and experimental road and modal test results. A novel system identification approach is used, employing both lab-based modal tests, and modal data derived using the Natural Excitation Technique (NExT), a scheme that utilizes the roadway surface as a natural forcing function. The use of a cab isolation system is investigated with the computer model for purposes of improving the ride quality of the vehicle. To validate these analytical predictions, an engineering prototype vehicle was developed, which included a cab isolation system, to experimentally assess ride quality. Ride quality improvements due to the addition of the isolation system are then assessed both experimentally and analytically, and the results are compared.

  19. The nuclear research centre at Bariloche, Argentina

    International Nuclear Information System (INIS)

    The nuclear research centre at Bariloche (CAB) is one of the four centres under the Atomic Energy Commission of Argentina (CNEA). The research programme of CAB addresses various issues like nuclear reactor development, nuclear fuel and fuel cycle, applications of radioisotopes and radiation, and waste management. There is also a basic nuclear science component. The human resource development in the areas of physics and nuclear engineering is done in an associated Balseiro Institute which has undergraduate and graduate programmes as well as doctoral and postdoctoral research. The Centre interacts well with the society and provides services in the nuclear area. It has a close interaction with the nuclear sector of Argentina as also with many international organisations. Regulatory control over the Centre is carried out by the Nuclear Regulatory Authority of Argentina. (author)

  20. Gene : CBRC-MMUS-04-0019 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-04-0019 4 A Odorant/olfactory and gustatory receptors O13J1_HUMAN 1e-145 ...82% ref|NP_062359.1| olfactory receptor 71 [Mus musculus] emb|CAB55597.1| olfactory receptor [Mus musculus] ...emb|CAB96152.1| olfactory receptor [Mus musculus] gb|AAL60904.1| olfactory receptor MOR262-4 [Mus musculus] ...gb|AAP70821.1| olfactory receptor Olfr71 [Mus musculus] emb|CAM17056.1| olfactory receptor 71 [Mus mus...culus] gb|AAI41883.1| Olfactory receptor 71 [Mus musculus] gb|AAI41893.1| Olfactory receptor 71 [Mus musculus

  1. Aspects to improve cabin comfort of wheel loaders and excavators according to operators.

    Science.gov (United States)

    Kuijt-Evers, L F M; Krause, F; Vink, P

    2003-05-01

    Comfort plays an increasingly important role in interior design of earth moving equipment. Although research has been conducted on vehicle interiors of wheel loaders and excavators, hardly any information is known about the operator's opinion. In this study a questionnaire was completed by machine operators to get their opinion about aspects which need to be improved in order to design a more comfortable vehicle interior. The results show that almost half of the operators rate the comfort of their cabin "average" or "poor". According to the operators, cab comfort of wheel loaders can be increased by improving seat comfort. Besides improving seat comfort, cabin comfort of excavators can be improved by changing the cab design (including dimensions, ingress/egress), view, reliability, and climate control. PMID:12737927

  2. Preparation of collagen modified photopolymers: a new type of biodegradable gel for cell growth.

    Science.gov (United States)

    Bayramoğlu, Gülay; Kayaman-Apohan, Nilhan; Akçakaya, Handan; Vezir Kahraman, Memet; Erdem Kuruca, Serap; Güngör, Atilla

    2010-02-01

    In this study a new branched methacrylated poly(propylene glycol-co-lactic acid) (PPG-PLA-IEM) and methacrylated cellulose acetate butyrate resin (CAB-IEM) were synthesized. Hydrogels with various amounts of PPG-PLA-IEM and CAB-IEM (25, 50 and 75 wt% IEM modified) were prepared by photopolymerization. Collagen tethered PEG-monoacrylate (PEGMA-collagen) was prepared and introduced as a bioactive moiety to modify the hydrogel in order to enhance cell affinity. In vitro attachment and growth of 3T3 mouse fibroblasts and human umbilical vein endothelial cells (HUVEC) on the hydrogels with and without collagen were also investigated. It was observed that, the collagen improves the cell adhesion onto the hydrogel surface. With the increasing amount of collagen, cell viability increased by 28% for ECV304 (P < 0.05) and 30% for 3T3 (P < 0.05). PMID:19936889

  3. Are interventions for improving the quality of services provided by specialized drug shops effective in sub-Saharan Africa? A systematic review of the literature

    OpenAIRE

    Wafula, Francis N.; Goodman, Catherine A

    2010-01-01

    Purpose We set out to determine effectiveness of interventions for improving the quality of services provided by specialized drug shops in sub-Saharan Africa. Data sources We searched PubMed, CAB Abstracts, Web of Science, PsycINFO and Eldis databases and websites for organizations such as WHO and Management Sciences for Health. Finally, we searched manually through the references of retrieved articles. Study selection Our search strategy included randomized trials, time-series studies and be...

  4. Suplemento múltiplo com ionóforos para novilhos em pasto: desempenho

    Directory of Open Access Journals (Sweden)

    M.H.F Mourthe

    2011-02-01

    Full Text Available Avaliou-se o desempenho de 25 novilhos Holandês x Zebu, castrados, com média de peso vivo inicial de 265±50 kg, sob pastejo emBrachiaria decumbens, distribuídos em cinco grupos e em cinco piquetes, segundo os tratamentos: controle - suplementação múltipla sem ionóforos (CONT; suplementação múltipla com 100mg/cab/dia de monensina (M100; suplementação múltipla com 200mg/cab/dia de monensina (M200; suplementação múltipla com 100mg/cab/dia de lasalocida (L100; suplementação múltipla com 200mg/cab/dia de lasalocida (L200. O período experimental foi de 105 dias, com rotação dos grupos nos piquetes a cada 21 dias. A suplementação foi fornecida ad libitum. A avaliação de desempenho ocorreu mediante a pesagem dos animais, em jejum de alimento e água de 14 horas, no início de cada período e término do experimento. Os animais alimentados com suplementos com ionóforos apresentaram maior ganho de peso em relação aos do controle (0,357 vs. 0,268; P = 0,0068. Entre os ionóforos, os animais alimentados com lasalocida ganharam mais peso (0,398 vs. 0,333; P=0,0175. O melhor desempenho pode ser explicado pelo maior consumo dos suplementos pelos animais alimentados com lasalocida (0,53 vs. 0,42; P<0,0001

  5. Increased Lipid Levels Improves after Treatment with Cabergolin in Patients with Prolactinoma

    OpenAIRE

    Tuna, Mazhar Muslum; Aycicek Dogan, Bercem; Navdar Basaran, Mehtap; Arduc, Ayse; Berker, Dilek; Guler, Serdar

    2015-01-01

    AbstractIt has been suggested that hyperprolactinemia may be associated with obesity and dyslipidemia. However it is not fully understood that dyslipidemia is occurs independently or due to obesity. The study was aimed to investigate lipid abnormalities and androgen hormone levels before and after cabergolin (CAB) treatment in non- obese premenauposal patients with prolactinoma. This study was a single-centre, prospective, case–control study, consisted of 53 patients with symptomatic prolacti...

  6. The development of a frameless glass door made for wheel loaders

    OpenAIRE

    Hult, Josefin

    2014-01-01

    This thesis performed on master level covers an assignment given by the cab division at Volvo Construction Equipment (Eskilstuna, Sweden). The thesis has been carried out by Josefin Hult during the period 2014-01-23 to 2014-05-30 at Mälardalen University. Volvo Construction Equipment manufactures products including wheel loaders, backhoe loaders and articulated haulers. The assignment involves developing the standard door for larger wheel loaders. The current door has a welded frame surroundi...

  7. Effects in service of the staggered construction of cable-stayed bridges built on temporary supports

    OpenAIRE

    Lozano Galant, Jose Antonio; Paya-Zaforteza, Ignacio; Turmo Coderque, José

    2015-01-01

    Cable-stayed bridges can be rarely built on a single construction stage and staggered construction is commonly used. The effects of this staggered construction are not only economical as they might also play an important role in the structural behaviour in service. Despite of this importance, these effects are rarely included into the definition of the structural response in service. In order to fill this gap, this paper deals with the effects in service of the staggered erection of steel cab...

  8. Preliminary technical data summary No. 3 for the Defense Waste Processing Facility

    International Nuclear Information System (INIS)

    This document presents an update on the best information presently available for the purpose of establishing the basis for the design of a Defense Waste Processing Facility. Objective of this project is to provide a facility to fix the radionuclides present in Savannah River Plant (SRP) high-level liquid waste in a high-integrity form (glass). Flowsheets and material balances reflect the alternate CAB case including the incorporation of low-level supernate in concrete

  9. 49 CFR Appendix A to Part 533 - Example of Calculating Compliance Under § 533.5 Paragraph (g)

    Science.gov (United States)

    2010-10-01

    ... ECONOMY STANDARDS Pt. 533, App. A Appendix A to Part 533—Example of Calculating Compliance Under § 533.5... 2012 as follows: Appendix A, Table 1 Model type Group Carline name Basic engine(L) Transmission class Description Actualmeasured fuel economy (mpg) Volume 1 Pickup A 2WD 4 A5 Reg cab, MB 27.1 800 2 Pickup B 2WD...

  10. Intake fraction of primary pollutants: motor vehicle emissions in the South Coast Air Basin

    OpenAIRE

    J. D. Marshall; W. J. Riley; McKone, T.E.; Nazaroff, William W.

    2003-01-01

    The intake fraction is defined for a specific species and emission source as the ratio of attributable population intake to total emissions. Focusing on California's South Coast Air Basin (SoCAB) as a case study, we combine ambient monitoring data with time-activity patterns to estimate the population intake of carbon monoxide and benzene emitted from motor vehicles during 1996-1999. In addition to exposures to ambient concentrations, three microenvironments are considered in which the exposu...

  11. Railway driving operations and cognitive ergonomics issues in the Norwegian railway : a systems analysis

    OpenAIRE

    2007-01-01

    In this study, an initial systems-based analysis was performed within the Norwegian railway. This approach to system safety attempts to provide information regarding the latent, system-related factors leading up to an unwanted event. The primary data includes two semi structured group interviews with safety officials, two individual semi structured interviews with safety officials, one cognitive interview (CI) with a certified train driver, and two ethnographic observations with in-cab interv...

  12. An Italian Biomedical Publications Database

    OpenAIRE

    De Robbio, Antonella; Mozzati, Paola; Lazzari, Luigina; Maguolo, Dario; Dolfino, Manuela; Gradito, Paola

    2002-01-01

    Periodical scientific literature is one of the most important information sources for the scientific community and particularly for biomedicine. As regards Italian publications today, a part from very few laudable exceptions, there is a lack of the instruments necessary for accessing the information that they contain. With over 700 Italian biomedical texts, only 25% are mentioned in the more important biomedical data banks, such as Medline, Embase, Pascal, CAB, with unfortunately a great deal...

  13. Historical dynamics of Heracleum mantegazzianum invasion on regional and local scales

    Czech Academy of Sciences Publication Activity Database

    Pyšek, Petr; Müllerová, Jana; Jarošík, Vojtěch

    Wallingford: CAB International, 2007 - (Pyšek, P.; Cock, M.; Nentwig, W.; Ravn, H.), s. 42-54 ISBN 978-1-84593-206-0 R&D Projects: GA MŠk(CZ) LC06073 Grant ostatní: -(XE) EVK2-CT-2001-00128 Institutional research plan: CEZ:AV0Z60050516 Keywords : alien plant * aerial photographs * course of invasion Subject RIV: EF - Botanics

  14. Solar Control Glazing for Trucks

    OpenAIRE

    Tavast, Johan

    2007-01-01

    This thesis concerns the use of solar control and electrochromic glazing in trucks. The purpose has been to study the decrease in solar energy transport into the cab and how to utilize the technology. The solar spectrum consists of both visible light and near-IR radiation, and solar control glazing transmits the majority of the visible light and reflects or absorbs most of the near-IR radiation. Electrochromic glazing has variable transmittance, which enables the driver to regulate the energy...

  15. Final Report of the International Agribusiness Task Force

    OpenAIRE

    Boland, Michael A.

    2012-01-01

    Background: The National Food and Agribusiness Management Education Commission (NFAMEC whose materials can be found at https://www.agecon.purdue.edu/cab/NFAMEC/home.htm) issued a set of recommendations to the U.S. Department of Agriculture in December 2006 based upon an extensive three year study of agribusiness management curricula in more than 160 four year programs and 40 two year programs in the United States. The NFAMEC worked with over 40 faculty and industry representatives in preparin...

  16. CRANIUM: Device for Improving Crane Productivity and Safety

    OpenAIRE

    ECT Team, Purdue

    2007-01-01

    Cranes are the most important pieces of equipment on many construction sites. CRANIUM is a video system designed to improve productivity and safety of crane operations by improving communications. A video camera mounted on the crane bottom transmits an image to the television monitor in the crane cab. The operator has a real-time picture of the loads and craftsmen that might otherwise be out of the direct line of sight.

  17. Quantifying Molecular Hydrogen Emissions and an Industrial Leakage Rate for the South Coast Air Basin of California

    Science.gov (United States)

    Irish, M. C.; Schroeder, J.; Beyersdorf, A. J.; Blake, D. R.

    2015-12-01

    The poorly understood atmospheric budget and distribution of molecular hydrogen (H2) have invited further research since the discovery that emissions from a hydrogen-based economy could have negative impacts on the global climate system and stratospheric ozone. The burgeoning fuel cell electric vehicle industry in the South Coast Air Basin of California (SoCAB) presents an opportunity to observe and constrain urban anthropogenic H2 emissions. This work presents the first H2 emissions estimate for the SoCAB and calculates an upper limit for the current rate of leakage from production and distribution infrastructure within the region. A top-down method utilized whole air samples collected during the Student Airborne Research Program (SARP) onboard the NASA DC-8 research aircraft from 23-25 June 2015 to estimate H2 emissions from combustion and non-combustion sources. H2:carbon monoxide (CO) and H2:carbon dioxide ratios from airborne observations were compared with experimentally established ratios from pure combustion source ratios and scaled with the well-constrained CO emissions inventory to yield H2 emissions of 24.9 ± 3.6 Gg a-1 (1σ) from combustion engines and 8.2 ± 4.7 Gg a-1 from non-combustion sources. Total daily production of H2 in the SoCAB was compared with the top-down results to estimate an upper limit leakage rate (5%) where all emissions not accounted for by incomplete combustion in engines were assumed to be emitted from H2 infrastructure. For bottom-up validation, the NOAA Hybrid Single Particle Lagrangian Integrated Trajectory dispersion model was run iteratively with all known stationary sources in attempt to constrain emissions. While this investigation determined that H2 emissions from non-combustion sources in the SoCAB are likely significant, more in-depth analysis is required to better predict the atmospheric implications of a hydrogen economy.

  18. Inefficiency of sanitation measures aboard commercial aircraft: environmental pollution and disease.

    Science.gov (United States)

    Kikuchi, R

    1977-07-01

    Recent investigations at Tokyo International Airport have proven that environmental pollution resulting from the inefficient disposal of human excretion aboard aircraft is an important problem from the standpoint of quarantine. It is, therefore, recommended that the worldwide aviation industry take immediate measures to improve conditions and eliminate this problem, which has thus far been ignored by aircraft designers, airport administration, and CAB personnel. PMID:329830

  19. Long-Haul Truck Sleeper Heating Load Reduction Package for Rest Period Idling: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, Jason; Kekelia, Bidzina; Tomerlin, Jeff; Kreutzer, Cory; Adelman, Steve; Yeakel, Skip; Luo, Zhiming; Zehme, John

    2016-03-24

    Annual fuel use for sleeper cab truck rest period idling is estimated at 667 million gallons in the United States, or 6.8% of long-haul truck fuel use. Truck idling during a rest period represents zero freight efficiency and is largely done to supply accessory power for climate conditioning of the cab. The National Renewable Energy Laboratory's CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck thermal management systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In addition, if the fuel savings provide a one- to three-year payback period, fleet owners will be economically motivated to incorporate them. For candidate idle reduction technologies to be implemented by original equipment manufacturers and fleets, their effectiveness must be quantified. To address this need, several promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. Load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, conductive pathways, and efficient equipment. Technologies in each of these focus areas were investigated in collaboration with industry partners. The most promising of these technologies were then combined with the goal of exceeding a 30% reduction in HVAC loads. These technologies included 'ultra-white' paint, advanced insulation, and advanced curtain design. Previous testing showed more than a 35.7% reduction in air conditioning loads. This paper describes the overall heat transfer coefficient testing of this advanced load reduction technology package that showed more than a 43% reduction in heating load. Adding an additional layer of advanced insulation

  20. Performance of cellulose acetate butyrate membranes in hyperfiltration of sodium chloride and urea feed solution

    Science.gov (United States)

    Wydeven, T.; Leban, M.

    1973-01-01

    Cellulose acetate butyrate (CAB) membranes are shown to give high salt and urea rejection with water flux of about 3 gallons/sq ft per day at 600 psig. Membranes prepared from a formulation containing glyoxal show a significant increase in flux and decrease in salt and urea rejection with drying time. Zero drying time gives maximum urea and salt rejection and is therefore most suitable for hyperfiltration of sodium chloride and urea feed solution.

  1. Preliminary technical data summary No. 3 for the Defense Waste Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Landon, L.F. (comp.)

    1980-05-01

    This document presents an update on the best information presently available for the purpose of establishing the basis for the design of a Defense Waste Processing Facility. Objective of this project is to provide a facility to fix the radionuclides present in Savannah River Plant (SRP) high-level liquid waste in a high-integrity form (glass). Flowsheets and material balances reflect the alternate CAB case including the incorporation of low-level supernate in concrete. (DLC)

  2. Instituting a filtration/pressurization system to reduce dust concentrations in a control room at a mineral processing plant

    OpenAIRE

    Noll, J; Cecala, A.; Hummer, J.

    2015-01-01

    The National Institute for Occupational Safety and Health has observed that many control rooms and operator compartments in the U.S. mining industry do not have filtration systems capable of maintaining low dust concentrations in these areas. In this study at a mineral processing plant, to reduce respirable dust concentrations in a control room that had no cleaning system for intake air, a filtration and pressurization system originally designed for enclosed cabs was modified and installed. T...

  3. Use of zeolite-rich rocks and waste materials for the production of structural lightweight concretes

    OpenAIRE

    De' Gennaro, Roberto; Langella, Alessio; D'Amore, Marco; Dondi, Michele; Colella, Abner; Cappelletti, Piergiulio; De Gennaro, Maurizio

    2009-01-01

    This paper aims at testing the use of mixtures constituted by natural zeolitized products and SiC-bearing industrial wastes (sludge deriving from polishing of porcelain stoneware tiles, hereafter DPM) for the production of lightweight expanded aggregates as constituents of structural and/or thermo-insulating lightweight concretes. Two commercial products have been used as zeolite natural source: Cab70 (Yellow facies of Campanian Ignimbrite) and IZclino (Turkish clinoptilolite-rich epiclastite...

  4. Konvence a experiment: Rosova pravidla českého pravopisu

    Czech Academy of Sciences Publication Activity Database

    Koupil, Ondřej

    -, č. 3 /42/ (2015), s. 93-104. ISSN 0323-0813 R&D Projects: GA MK(CZ) DF12P01OVV028 Keywords : orthography of Czech * Václav Jan Rosa * 17th century Subject RIV: AI - Linguistics http://www.ceeol.com/aspx/getdocument.aspx?logid=5&id=541f4c9b-cab9-4861-8f6e-9dd5f23ae2cb

  5. Neural correlate of spatial presence in an arousing and noninteractive virtual reality: an EEG and psychophysiology study

    OpenAIRE

    Baumgartner, Thomas; Valko, Lilian; Esslen, Michaela; Jäncke, Lutz

    2006-01-01

    Using electroencephalography (EEG), psychophysiology, and psychometric measures, this is the first study which investigated the neurophysiological underpinnings of spatial presence. Spatial presence is considered a sense of being physically situated within a spatial environment portrayed by a medium (e.g., television, virtual reality). Twelve healthy children and 11 healthy adolescents were watching different virtual roller coaster scenarios. During a control session, the roller coaster cab d...

  6. Molecular genetics, physiology and biology of self-incompatibility in Brassicaceae

    OpenAIRE

    Watanabe, Masao; Suwabe, Keita; Suzuki, Go

    2012-01-01

    Self-incompatibility (SI) is defined as the inability to produce zygotes after self-pollination in a fertile hermaphrodite plant, which has stamens and pistils in the same flower. This structural organization of the hermaphrodite flower increases the risk of self-pollination, leading to low genetic diversity. To avoid this problem plants have established several pollination systems, among which the most elegant system is surely SI. The SI trait can be observed in Brassica crops, including cab...

  7. Lyocell Fiber-Reinforced Cellulose Ester Composites - Surface and Consolidation Considerations, and Properties

    OpenAIRE

    Seavey, Kevin Christopher

    1999-01-01

    The objective of this thesis was to further develop the polymer composite system consisting of cellulose acetate butyrate (CAB) and high modulus, continuous, regenerated cellulose fiber (lyocell). Of particular concern were both the interfacial adhesion between the fiber and matrix and the consolidation process in the manufacture of these composite materials. Interfacial adhesion was found to be substantial due to the relative lack of the fiber pull-out phenomenon observed after tensil...

  8. Lyocell Fiber-Reinforced Cellulose Ester Composites-Manufacturing Considerations and Properties.

    OpenAIRE

    Ghosh, Indrajit

    1999-01-01

    Biodegradable thermoplastic composites were prepared using high modulus lyocell fibers and cellulose acetate butyrate (CAB). Two reinforcement fiber types: fabric and continuous fiber tow were used. Fabric had advantages of uniform alignment and easier processing, but lacked the use as a unidirectional reinforcement and a continuous method of matrix application. Three different matrix application methods were screened for both fiber types. Matrix application by suspension of particles in wate...

  9. Effect of the particle size and solids volume fraction on the thermal degradation behaviour of Invar 36 feedstocks

    OpenAIRE

    Hidalgo García, Javier; Fernández-Blázquez, J.P.; Jiménez Morales, Antonia; Barriere, T.; Gelin, J. C.; Torralba, José Manuel

    2014-01-01

    Degradation kinetics and the thermal stability of Invar 36 powder injection moulding feedstocks (PIM) based on cellulose acetate butyrate (CAB) and polyethylene glycol (PEG) binders were investigated using simultaneous thermogravimetric analysis (STA) and differential scanning calorimetry (DSC). The initial decomposition temperature (IDT) and the integral procedure decomposition temperature (IPDT) were used to analyse the thermal stability of the binder system as a function of the solid loadi...

  10. Thermal stability and degradation kinetics of feedstocks for powder injection moulding - A new way to determine optimal solid loading?

    OpenAIRE

    Hidalgo García, Javier; Jiménez Morales, Antonia; Torralba, José Manuel

    2013-01-01

    Degradation kinetics and the thermal stability of zircon powder injection moulding feedstocks (PIM) based on cellulose acetate butyrate (CAB) and polyethylene glycol (PEG) binders were investigated using simultaneous thermogravimetric analysis (STA). The initial decomposition temperature (IDT) and the integral procedure decomposition temperature (IPDT) were used to analyse the thermal stability of the binder system as a function of the solid loading content. The degradation kinetics was studi...

  11. Observer-based chaos synchronization in the generalized chaotic Lorenz systems and its application to secure encryption

    Czech Academy of Sciences Publication Activity Database

    Čelikovský, Sergej; Lynnyk, Volodymyr; Šebek, Michael

    San Diego: Omnipress, 2006, s. 3783-3788. ISBN 1-4244-0171-2. [IEEE Conference on Decision and Control /45./. San Diego (US), 13.12.2006-15.12.2006] R&D Projects: GA ČR GA102/05/0011 Institutional research plan: CEZ:AV0Z10750506 Keywords : nonlinear systems * chaotic systems Subject RIV: BC - Control Systems Theory http://www.ieeecss.org/CAB/conferences/cdc2006/index.php

  12. Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy

    OpenAIRE

    Weng, Stephen Franklin; Redsell, Sarah A; Swift, Judy A.; Yang, Min; Glazebrook, Cristine P

    2012-01-01

    Objective To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. Design Systematic review and meta-analysis. Search strategy Electronic database search of MEDLINE, EMBASE, PubMed and CAB Abstracts. Eligibility criteria Prospective observational studies following up children from birth for at least 2 years. Results Thirty prospective studies were identified. Significant and strong ind...

  13. Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy

    OpenAIRE

    Weng, Stephen Franklin; Redsell, Sarah A; Swift, Judy A.; Yang, Min; Glazebrook, Cristine P

    2012-01-01

    Objective To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. Design Systematic review and meta-analysis. Search strategy Electronic database search of MEDLINE, EMBASE, PubMed and CAB Abstracts. Eligibility criteria Prospective observational studies following up children from birth for at least 2 years. Results Thirty prospective studies were identified....

  14. Long-Term Acclimation of the Cyanobacterium Synechocystis sp PCC 6803 to High Light Is Accompanied by an Enhanced Production of Chlorophyll That Is Preferentially Channeled to Trimeric Photosystem I

    Czech Academy of Sciences Publication Activity Database

    Kopečná, Jana; Komenda, Josef; Bučinská, Lenka; Sobotka, Roman

    2012-01-01

    Roč. 160, č. 4 (2012), s. 2239-2250. ISSN 0032-0889 R&D Projects: GA MŠk(CZ) ED2.1.00/03.0110; GA ČR GAP501/10/1000; GA ČR GBP501/12/G055 Institutional support: RVO:61388971 Keywords : CAB-LIKE-PROTEINS * SP PCC-6803 * PHOTOSYNTHETIC APPARATUS Subject RIV: EE - Microbiology, Virology Impact factor: 6.555, year: 2012

  15. Congenital adrenal hyperplasia, CYP21 deficiency, screening and clinical aspects

    OpenAIRE

    Nordenström, Anna

    2001-01-01

    Congenital adrenal hyperplasia (CAH) is a group of recessively inherited disorders. More than 90% of all cases of CAB are caused by 21-hydroxylase deficiency. This enzyme deficiency results in reduced ability to synthesize cortisol and aldosterone and at the same time increased secretion of androgens. There is a wide spectrum of severity of the disease. The most severe forms of CAH are life-threatening, with the risk of a salt crisis in the neonatal period. CAH has special i...

  16. Posterior segment ocular manifestations of HIV/AIDS patients

    OpenAIRE

    Chiotan, C; Radu, L; Serban, R; Cornăcel, C; Cioboată, M; Anghelie, A

    2014-01-01

    Abstract Human immunodeficiency virus (HIV) has the ability to affect any organ in the body. In 70% of HIV -infected patients ocular manifestations were observed, these, in the vast majority reflect the systemic disease and may be the first signs of disseminated infections. Aim: The purpose of this paper is to determine the prevalence of posterior segment ocular manifestations in HIV / AIDS (Acquired Immunodeficiency Syndrome) patients. Method: The study is retrospective, conducted in the Cab...

  17. HFC-152a and HFC-134a emission estimates and characterization of CFCs, CFC replacements, and other halogenated solvents measured during the 2008 ARCTAS campaign (CARB phase over the South Coast Air Basin of California

    Directory of Open Access Journals (Sweden)

    B. Barletta

    2010-11-01

    Full Text Available This work presents results from the NASA Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS study. Whole air samples were obtained on board research flights that flew over California during June 2008 and analyzed for selected volatile organic compounds, including several halogenated species. Samples collected over the South Coast Air Basin of California (SoCAB, which includes much of Los Angeles (LA County, were compared with samples from inflow air masses over the Pacific Ocean. The levels of many halocarbon species were enhanced significantly over the SoCAB, including compounds regulated by the Montreal Protocol and subsequent amendments (e.g., enhancements of 13 pptv and 11 pptv for CFC-11 and CFC-12, respectively. Emissions estimates of HFC-152a (0.98±0.05 Gg and HFC-134a (1.40±0.11 Gg in LA County for 2008 were obtained using the observed HFC:CO enhancement ratio. The emission rates were extrapolated to the SoCAB (1.48±0.07 Gg for HFC-152a and 2.12±0.17 Gg for HFC-134a and US (30.1±1.5 Gg for HFC-152a and 43.0±3.4 Gg for HFC-134a using population data. In addition, emission rates of the two HFCs in LA County and SoCAB also were calculated by a second method that utilizes air quality modeling. Estimates obtained using both methods agree well.

  18. Balancing of the anthropomorphous robot walking

    Science.gov (United States)

    Devaev, V. M.; Nikitina, D. V.; Fadeev, A. Y.

    2016-06-01

    Anthropomorphic robots are designed a human environment operates: buildings and structures, cabs and etc. The movement of these robots is carried out by walking which provides high throughput to overcome natural and manmade obstacles. The article presents some algorithm results for dynamic walking on the anthropomorphic robot AR601 example. The work is performed according to the Russian Government Program of Competitive Growth of Kazan Federal University.

  19. Molecular Analysis of the pmo (Particulate Methane Monooxygenase) Operons from Two Type II Methanotrophs

    OpenAIRE

    Gilbert, Bettina; McDonald, Ian R.; Finch, Ruth; Stafford, Graham P.; Nielsen, Allan K.; Murrell, J. Colin

    2000-01-01

    The particulate methane monooxygenase gene clusters, pmoCAB, from two representative type II methanotrophs of the α-Proteobacteria, Methylosinus trichosporium OB3b and Methylocystis sp. strain M, have been cloned and sequenced. Primer extension experiments revealed that the pmo cluster is probably transcribed from a single transcriptional start site located 300 bp upstream of the start of the first gene, pmoC, for Methylocystis sp. strain M. Immediately upstream of the putative start site, co...

  20. Can LTE become an alternative to GSM-R?

    OpenAIRE

    Sniady, Aleksander; Soler, José

    2013-01-01

    GSM-R is the first widely adopted international mobile communication network for railways. It is a part of the European Rail Traffic Management System (ERTMS), which substitutes legacy national railway signaling technologies. GSM-R is designed to provide two fundamental services: transmission of the European Train Control System (ETCS) messages and voice communication for railways. ETCS system offers safe and reliable in-cab signaling and train supervision, which reduces the risk of train dri...

  1. Background material properties of selected silicone potting compounds and raw materials for their substitutes

    Energy Technology Data Exchange (ETDEWEB)

    Flowers, G.L.; Switzer, S.T.

    1978-05-01

    Since Dow Corning discontinued production of 93-119, 93-120, 93-122, Pantex joined with the Lawrence Livermore Laboratory to develop substitutes for these materials. Raw materials chosen for this project include Sylgard 184, Sylgard 186, Q3-6527 Dielectric Gel, Q3-6559 Accelerator, DC 1107 and Cab-o-Sil MS-75. This report deals with physical and chemical properties of these materials.

  2. Effect of Water Stress on The Some Evegatif Growth Parameters of Cultivar Grafted on Different Rootstocks 0900 Ziraat Sweet Cherry

    OpenAIRE

    Cenk KÜÇÜKYUMUK; Sarısu, Hasan Cumhur; Halit YILDIZ; KAÇAL, Emel; KOÇAL, Hakkı

    2015-01-01

    Sweet cherry production areas have been increasing in last years and rootstocks which have different growing characteristic are being used. Therefore, responses of new and present rootstocks to water stress must be determined. For this purpose, one year old 0900 Ziraat sweet cherry variety grafted on Mahaleb (Prunus mahalep L.), Mazzard (Prunus avium L.), Ma x Ma 14 (Prunus mahalep L. x Prunus avium L.), CAB 6 (Prunus cerasus L.) ve Gisela 6 (Prunus cerasus x P. canescens L.) rootstocks were ...

  3. Optimized Hyper Beamforming of Linear Antenna Arrays Using Collective Animal Behaviour

    OpenAIRE

    Gopi Ram; Durbadal Mandal; Rajib Kar; Sakti Prasad Ghoshal

    2013-01-01

    A novel optimization technique which is developed on mimicking the collective animal behaviour (CAB) is applied for the optimal design of hyper beamforming of linear antenna arrays. Hyper beamforming is based on sum and difference beam patterns of the array, each raised to the power of a hyperbeam exponent parameter. The optimized hyperbeam is achieved by optimization of current excitation weights and uniform interelement spacing. As compared to conventional hyper beamforming of linear antenn...

  4. Study on neutron scattering in light water

    Directory of Open Access Journals (Sweden)

    Scotta Juan Pablo

    2016-01-01

    Full Text Available It is presented a method to produce covariance matrices of the light water total cross section from thermal scattering laws of the JEFF-3.1.1 nuclear data library and CAB model. The generalized least square method was used to fit the LEAPR module parameters of the processing tool NJOY with light water experimental transmission measurements at 293.6K with CONRAD code. The marginalization technique was applied to account for systematic uncertainties.

  5. Association between self-reported oral health, tooth loss and atherosclerotic burden

    Directory of Open Access Journals (Sweden)

    Maximiliano Schünke Gomes

    2012-10-01

    Full Text Available Previous studies have suggested that oral diseases may influence the development of atherosclerosis. The aim of this study was to test the hypothesis that poor self-reported oral health (SROH and tooth loss are positively associated with coronary atherosclerotic burden (CAB. 382 consecutive subjects undergoing coronary angiography were included. Socio-demographic characteristics, cardiovascular risk factors and oral health status were collected using a standardized questionnaire, including data on SROH and use of dental prosthesis. Number of teeth and anthropometric measures were collected through clinical examinations. CAB at coronary angiography was quantified using the Friesinger score (FS. Prevalence ratios (PR were calculated with Poisson regression analyses. Mean age was 60.3 ± 10.8 years, with 63.2% males. In the bivariate analysis, there was a significant association (p 60y (PR = 1.01, 95%CI = 1.02-1.16, male gender (PR = 1.11, 95%CI = 1.03-1.19, smoking (PR = 1.08, 95%CI = 1.01- 1.16, hypertension (PR = 1.12, 95%CI = 1.03-1.22, diabetes (PR = 1.17, 95%CI = 1.05-1.21, poor SROH (PR = 1.22, 95%CI = 1.02-1.46 and tooth loss (< 20teeth present (PR = 1.10, 95%CI = 1.02-1.19. The use of dental prosthesis was not associated with CAB. The multivariate models, adjusted for age, gender, smoking, hypertension, diabetes and dyslipidemia showed that poor SROH (p = 0.03 and tooth loss (p = 0.02 were independently associated with CAB, confirming the study hypothesis.

  6. Diesel locomotive MaK 2000 in a configuration with hydrodynamic transmission; Auslegung der Diesellokomotive MaK 2000 mit hydrodynamischer Leistungsuebertragung. Teil 2

    Energy Technology Data Exchange (ETDEWEB)

    Schwab, W.; Zwicker, D. [Vossloh Locomotives GmbH, Kiel (Germany)

    2005-07-01

    The MaK 2000 locomotive from Vossloh Locomotives GmbH was designed as a four-axle bogie loco with tractive power of 2240 kW, hydrodynamic transmission, two end cabs and a length between buffers of 17.4 m. A new version with power raised to 2700 kW while retaining the major components of the power train and the loco structure will shortly be ready for the market. (orig.)

  7. A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes

    OpenAIRE

    Wiebe Natasha; Padwal Raj; Field Catherine; Marks Seth; Jacobs Rene; Tonelli Marcello

    2011-01-01

    Abstract Background The major metabolic complications of obesity and type 2 diabetes may be prevented and managed with dietary modification. The use of sweeteners that provide little or no calories may help to achieve this objective. Methods We did a systematic review and network meta-analysis of the comparative effectiveness of sweetener additives using Bayesian techniques. MEDLINE, EMBASE, CENTRAL and CAB Global were searched to January 2011. Randomized trials comparing sweeteners in obese,...

  8. An Algorithm for Global Optimization Inspired by Collective Animal Behavior

    OpenAIRE

    Erik Cuevas; Mauricio González; Daniel Zaldivar; Marco Pérez-Cisneros; Guillermo García

    2012-01-01

    A metaheuristic algorithm for global optimization called the collective animal behavior (CAB) is introduced. Animal groups, such as schools of fish, flocks of birds, swarms of locusts, and herds of wildebeest, exhibit a variety of behaviors including swarming about a food source, milling around a central locations, or migrating over large distances in aligned groups. These collective behaviors are often advantageous to groups, allowing them to increase their harvesting efficiency, to follow b...

  9. Cities with camera-equipped taxicabs experience reduced taxicab driver homicide rates: United States, 1996–2010

    OpenAIRE

    Chaumont Menéndez, Cammie; Amandus, Harlan; Damadi, Parisa; Wu, Nan; Konda, Srinivas; Hendricks, Scott

    2014-01-01

    Background Driving a taxicab remains one of the most dangerous occupations in the United States, with leading homicide rates. Although safety equipment designed to reduce robberies exists, it is not clear what effect it has on reducing taxicab driver homicides. Findings Taxicab driver homicide crime reports for 1996 through 2010 were collected from 20 of the largest cities (>200,000) in the United States: 7 cities with cameras installed in cabs, 6 cities with partitions installed, and 7 citie...

  10. Ultraviolet-B responses of nuclear genes encoding light-harvesting complex II proteins in pea (Pisum sativum) are altered by norflurazon- and photobleaching-induced chloroplast changes

    International Nuclear Information System (INIS)

    The role of functional and intact chloroplasts in mediating the ultraviolet-B (UV-B, 290–320 nm) regulation of two nuclear genes encoding light-harvesting complex II proteins in pea (Pisum sativum L. cv. Extra Early Alaska) was studied. Plants with chloroplasts lacking or containing carotenoids and functional photosystem II were obtained by growth under dim red light (0.2 µmol m−2 s−1) in the presence or absence of norflurazon (NF), an inhibitor of carotenoid biosynthesis. The NF-treatment resulted in an increase in AB80 (lhcb1*2) mRNA but no substantial change in Cab-8 (lhcb1*4) mRNA, indicating that the mRNA accumulations for AB80 and Cab-8 were differently correlated with the presence and absence of carotenoids. The mRNA levels for both Cab-8 and AB80 in the NF-treated plants were reduced to the same extent by partially photobleaching the chloroplasts with 3 h of higher intensity white light (W, 110 µmol m−2 s−1), suggesting that chloroplast integrity was equally important for transcript accumulation of both genes. The mRNAs of both Cab-8 and AB80 in non-NF-treated control plants were decreased by UV-B irradiation, with the level of AB80 mRNA reduced to a greater extent. The UV-B-induced mRNA reduction of both genes was inhibited by NF. The difference between the UV-B responses of the two genes was unaffected by NF, but was abolished by photobleaching the NF-treated plants prior to the UV-B irradiation. Therefore, the presence of carotenoids enhanced rather than prevented the UV-B down-regulation, and the difference in UV-B responses of the two genes may be dependent on chloroplast integrity. (author)

  11. Effects of uranium mine effluents (Caldas, Southeastern Brazil) on the aquatic biota: preliminary study on the phytoplankton community

    International Nuclear Information System (INIS)

    The present study assessed the composition of the phytoplankton community and the physicochemical variables in an area located within the ore treatment unit - Brazilian Nuclear Industries, in Caldas and also in 'Antas' dam, which is under the influence of the treatment unit. Water samples were taken from three sites; one located within the treatment unit (site CM), which receives non-treated effluents generated during the mining process; and the other sites are located in 'Antas' dam (sites Cab and 41). We determined the values of dissolved oxygen, pH, chlorophyll a, hardness, thorium, uranium, sulfate and total organic nitrogen in water samples, and identified the phytoplankton community in October 2008 and January 2009. Water samples from the site CM exhibited lower pH medium values (3.9) than from the site 41 (6.9). The highest medium value of chlorophyll a was detected in water samples at site CM (5 μg L-1), whereas the lowest value was recorded at site 41 (0.47 μg L-1). Higher medium values of sulfate were detected in water samples from site CM (1743 mg L-1) compared to site Cab (110.11 mg L-1). We identified six classes in the phytoplankton community at site CM and eight classes at sites Cab and 41. Total average density of phytoplankton were 444 ind mL-1, 316 ind mL-1 and 303 ind mL-1 at points Cab, 41 and CM, respectively. The results obtained show that the environmental conditions at site CM are not favorable to the maintenance of a high density in the phytoplankton community. (author)

  12. Seed ecology of Heracleum mantegazzianum and H. sosnowskyi, two invasive species with different distributions in Europe

    Czech Academy of Sciences Publication Activity Database

    Moravcová, Lenka; Pyšek, Petr; Pergl, Jan; Perglová, Irena; Gudžinskas, Z.

    Wallingford: CAB International, 2007 - (Pyšek, P.; Cock, M.; Nentwig, W.; Ravn, H.), s. 157-169 ISBN 978-1-84593-206-0 R&D Projects: GA ČR(CZ) GA206/05/0323 Grant ostatní: -(XE) EVK2-CT-2001-00128 Institutional research plan: CEZ:AV0Z60050516 Keywords : Seed Bank * germination * distribution Subject RIV: EF - Botanics

  13. Evaluating the safety and immunogenicity of yellow fever vaccines: a systematic review

    OpenAIRE

    Thomas, Roger

    2015-01-01

    Roger E Thomas Department of Family Medicine, G012 Health Sciences Center, University of Calgary Medical School, Calgary, AB, Canada Purpose: To review the safety and immunogenicity of yellow fever vaccines. Literature search: The Cochrane Library (including the Cochrane CENTRAL Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and the NHS Database of Abstracts of Reviews of Effects); MEDLINE; EMBASE; BIOSIS Previews; Global Health; CAB Abstracts; and the Lilacs Dat...

  14. Nanostructures on spin-coated polymer films controlled by solvent composition and polymer molecular weight

    Energy Technology Data Exchange (ETDEWEB)

    Dario, Aline F.; Macia, Henrique B.; Petri, Denise F.S., E-mail: dfsp@iq.usp.br

    2012-12-01

    In this study we systematically investigated how the solvent composition used for polymer dissolution affects the porous structures of spin-coated polymers films. Cellulose acetate butyrate (CAB) and poly(methyl methacrylate) with low (PMMA-L) and high (PMMA-H) molecular weights were dissolved in mixtures of acetone (AC) and ethyl acetate (EA) at constant polymer concentration of 10 g/L The films were spin-coated at a relative air humidity of 55 {+-} 5%, their thickness and index of refraction were determined by means of ellipsometry and their morphology was analyzed by atomic force microscopy. The dimensions and frequency of nanocavities on polymer films increased with the acetone content ({phi}{sub AC}) in the solvent mixture and decreased with increasing polymer molecular weight. Consequently, as the void content increased in the films, their apparent thicknesses increased and their indices of refraction decreased, creating low-cost anti-reflection surface. The void depth was larger for PMMA-L than for CAB. This effect was attributed to different activities of EA and AC in CAB or PMMA-L solution, the larger mobility of chains and the lower polarity of PMMA-L in comparison to CAB. - Highlights: Black-Right-Pointing-Pointer Nanostructures in spin-coated polymer films depend on the solvent vapor pressure. Black-Right-Pointing-Pointer Anti-reflection polymer films are produced at high solvent vapor pressure. Black-Right-Pointing-Pointer Only shallow cavities are obtained in films of polymers with high molecular weight.

  15. Loss and recovery of an 192Ir gamma radiography exposure device

    International Nuclear Information System (INIS)

    A radiography exposure device containing 88.8 GBq (2.4 Ci) of 192Ir is inadvertently left in a taxi cab which has sped off before the equipment could be unloaded. The joint effort between the licensee and Philippine Nuclear Research Institute (PNRI) utilizing the tri-media in searching for the missing device resulted in its recovery 32 days later. The regulatory actions taken by the PNRI during and after the accident are discussed. (author). 3 refs

  16. Some examples of spin-off technologies: San Carlos de Bariloche

    International Nuclear Information System (INIS)

    The Bariloche Atomic Center (CAB) and the Balseiro Institute, both in San Carlos de Bariloche, are mainly devoted to scientific research and development, the first one; and to education and training the second one. Besides providing specialists in physics and nuclear engineering for research centers in Argentina and abroad, both establishments are transferring technologies and providing services in different fields such as waste management, metallurgy, forensic sciences, medicine, geology, modeling, archaeology, paleontology, etc

  17. Traktionsantrieb mit linearem geschalteten Reluktanzmotor für ein autonomes Bahnfahrzeug

    OpenAIRE

    Schneider, Tobias

    2014-01-01

    Im Rahmen des NBP-Projekts wird ein Bahnsystem entwickelt, welches auf kleinen, autonom verkehrenden Fahrzeugen beruht. Diese so genannten RailCabs werden fahrerlos betrieben und können sich selbstständig zu Konvois zusammenschließen. Die Traktionskraft und damit die Beschleunigung der Fahrzeuge wird über das magnetische Luftspaltfeld eines Linearmotors erzeugt. Die Luftspaltbreite zwischen den strecken- und fahrzeugseitigen Motorteilen ist sowohl durch Witterungsbedingungen als auch durch Al...

  18. Porovnání traktorů výkonové třídy nad 300 kW

    OpenAIRE

    Klimešová, Radka

    2012-01-01

    This thesis aims to compare the performance class of tractors above 300 kW according to technical parameters and Exploitation, propose suitable machinery for the tractor trains and lines. The initialport of the thesis is devoted to the technical parameters of tractors, especially the engine, transmission system, chassis, cab, electro-hydraulic system and electronic equipment. In the conclusion, the individual tractors are compared and evaluated according to the selected method.

  19. Fine-scale simulation of ammonium and nitrate over the South Coast Air Basin and San Joaquin Valley of California during CalNex-2010

    Science.gov (United States)

    Kelly, James T.; Baker, Kirk R.; Nowak, John B.; Murphy, Jennifer G.; Markovic, Milos Z.; VandenBoer, Trevor C.; Ellis, Raluca A.; Neuman, J. Andrew; Weber, Rodney J.; Roberts, James M.; Veres, Patrick R.; Gouw, Joost A.; Beaver, Melinda R.; Newman, Sally; Misenis, Chris

    2014-03-01

    National ambient air quality standards (NAAQS) have been set for PM2.5 due to its association with adverse health effects. PM2.5 design values in the South Coast Air Basin (SoCAB) and San Joaquin Valley of California exceed NAAQS levels, and NH4+ and NO3- make up the largest fraction of total PM2.5 mass on polluted days. Here we evaluate fine-scale simulations of PM2.5 NH4+ and NO3- with the Community Multiscale Air Quality model using measurements from routine networks and the California Research at the Nexus of Air Quality and Climate Change 2010 campaign. The model correctly simulates broad spatial patterns of NH4+ and NO3- including the elevated concentrations in eastern SoCAB. However, areas for model improvement have been identified. NH3 emissions from livestock and dairy facilities appear to be too low, while those related to waste disposal in western SoCAB may be too high. Analyses using measurements from flights over SoCAB suggest that problems with NH3 predictions can influence NO3- predictions there. Offline ISORROPIA II calculations suggest that overpredictions of NHx in Pasadena cause excessive partitioning of total nitrate to the particle phase overnight, while underpredictions of Na+ cause too much partitioning to the gas phase during the day. Also, the model seems to underestimate mixing during the evening boundary layer transition leading to excessive nitrate formation on some nights. Overall, the analyses demonstrate fine-scale variations in model performance within and across the air basins. Improvements in inventories and spatial allocations of NH3 emissions and in parameterizations of sea spray emissions, evening mixing processes, and heterogeneous ClNO2 chemistry could improve model performance.

  20. Simulerings- och optimeringsmodell för vibrationsdämpande förarhyttupphängning

    OpenAIRE

    Hansson, Per-Anders

    1991-01-01

    A time domain simulation model for the dynamic system chassi-suspension-cab is described and used. The validation showed good agreement between model and experimental results. The influence of different suspension parameters on vibration damping capacity and the requirement for free space in the construction were investigated. Particular emphasis was placed on the effects of passive non-linear suspension elements. An optimization model has been developed and used to optimize suspension parame...

  1. Evaluation of the efficiency of systems to reduce vibration on modern tracklaying tractors

    OpenAIRE

    Domenico Pessina; Davide Facchinetti; Valentina Bonalume

    2012-01-01

    Agricultural operators run a very high risk of exposure to mechanical vibration. To improve comfort, many different devices have recently been fitted to agricultural self-propelled machinery, especially on the most modern high-powered wheeled tractors. In contrast, agricultural tracklaying tractors are not equipped with a suspended cab floor and frequently poor or no seat suspension is fitted. Consequently, the levels of vibration measured in the driving seat of tracklaying tractors often wid...

  2. Quadratic Assignment of Hubs in p-Hub Median Problem

    DEFF Research Database (Denmark)

    Gelareh, Shahin

    We introduce Generalized p-Hub Median Problem (GpHMP) that seeks to locate p hub nodes and install p distinct hub facilities/operators on the hubs while discount factor resulted by consolidation of flow on the hub links depends on the facilities/operators that are installed/operating on both hub ......-points. The mathematical model is presented and numerical results on the instances of CAB and AP data sets are reported....

  3. Vehicle for underground hard coal mining. Fahrzeug fuer den untertaegigen Steinkohlenbergbau

    Energy Technology Data Exchange (ETDEWEB)

    Runge, W.; Kolk, T.

    1982-06-16

    The invention concerns a vehicle for underground hard coal mining, particularly for transport without rails, which is provided with a Diesel engine, for example and is made as a transport, tractor and/or carrier vehicle for working equipment. It consists in the main of a sub-frame carrying the required machine units and equipped with at least four wheels, on which a cab is set for the driver and other personnel.

  4. Fairing Well: Aerodynamic Truck Research at NASA Dryden Flight Research Center. From Shoebox to Bat Truck and Beyond

    Science.gov (United States)

    Gelzer, Christian

    2011-01-01

    In 1973 engineers at Dryden began investigating ways to reduce aerodynamic drag on land vehicles. They began with a delivery van whose shape they changed dramatically, finally reducing its aerodynamic drag by more than 5 percent. They then turned their attention to tracator-trailers, modifying a cab-over and reducing its aerodynamic drag by nearly 25 percent. Further research identified additional areas worth attention, but in the intervening decades few of those changes have appeared.

  5. Impact of Paint Color on Rest Period Climate Control Loads in Long-Haul Trucks: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J.; Kreutzer, C.; Jeffers, M.; Adelman, S.; Yeakel, S.; Brontz, P.; Olson, K.; Ohlinger, J.

    2014-02-01

    Cab climate conditioning is one of the primary reasons for operating the main engine in a long-haul truck during driver rest periods. In the United States, sleeper cab trucks use approximately 667 million gallons of fuel annually for rest period idling. The U.S. Department of Energy's National Renewable Energy Laboratory's (NREL) CoolCab Project works closely with industry to design efficient thermal management systems for long-haul trucks that minimize engine idling and fuel use while maintaining occupant comfort. Heat transfer to the vehicle interior from opaque exterior surfaces is one of the major heat pathways that contribute to air conditioning loads during long-haul truck daytime rest period idling. To quantify the impact of paint color and the opportunity for advanced paints, NREL collaborated with Volvo Group North America, PPG Industries, and Dometic Environmental Corporation. Initial screening simulations using CoolCalc, NREL's rapid HVAC load estimation tool, showed promising air-conditioning load reductions due to paint color selection. Tests conducted at NREL's Vehicle Testing and Integration Facility using long-haul truck cab sections, 'test bucks,' showed a 31.1% of maximum possible reduction in rise over ambient temperature and a 20.8% reduction in daily electric air conditioning energy use by switching from black to white paint. Additionally, changing from blue to an advanced color-matched solar reflective blue paint resulted in a 7.3% reduction in daily electric air conditioning energy use for weather conditions tested in Colorado. National-level modeling results using weather data from major U.S. cities indicated that the increase in heating loads due to lighter paint colors is much smaller than the reduction in cooling loads.

  6. Long-Haul Truck Sleeper Heating Load Reduction Package for Rest Period Idling

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, Jason; Kekelia, Bidzina; Tomerlin, Jeff; Kreutzer, Cory; Adelman, Steve; Yeakel, Skip; Luo, Zhiming; Zehme, John

    2016-06-01

    Annual fuel use for sleeper cab truck rest period idling is estimated at 667 million gallons in the United States, or 6.8% of long-haul truck fuel use. Truck idling during a rest period represents zero freight efficiency and is largely done to supply accessory power for climate conditioning of the cab. The National Renewable Energy Laboratory's CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck thermal management systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In addition, if the fuel savings provide a one- to three-year payback period, fleet owners will be economically motivated to incorporate them. For candidate idle reduction technologies to be implemented by original equipment manufacturers and fleets, their effectiveness must be quantified. To address this need, several promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. Load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, conductive pathways, and efficient equipment. Technologies in each of these focus areas were investigated in collaboration with industry partners. The most promising of these technologies were then combined with the goal of exceeding a 30% reduction in HVAC loads. These technologies included 'ultra-white' paint, advanced insulation, and advanced curtain design. Previous testing showed more than a 35.7% reduction in air conditioning loads. This paper describes the overall heat transfer coefficient testing of this advanced load reduction technology package that showed more than a 43% reduction in heating load. Adding an additional layer of advanced insulation

  7. Seed germination, Dispersal and Seed Bank in Heracleum mantegazzianum

    Czech Academy of Sciences Publication Activity Database

    Moravcová, Lenka; Pyšek, Petr; Krinke, L.; Pergl, Jan; Perglová, Irena; Thompson, K.

    Wallingford: CAB International, 2007 - (Pyšek, P.; Cock, M.; Nentwig, W.; Ravn, H.), s. 74-91 ISBN 978-1-84593-206-0 R&D Projects: GA ČR(CZ) GA206/05/0323 Grant ostatní: -(XE) EVK2-CT-2001-00128 Institutional research plan: CEZ:AV0Z60050516 Keywords : Germination * Dormancy * Seed Bank Subject RIV: EF - Botanics

  8. Effect of membrane polymeric materials on relationship between surface pore size and membrane fouling in membrane bioreactors

    Science.gov (United States)

    Miyoshi, Taro; Yuasa, Kotaku; Ishigami, Toru; Rajabzadeh, Saeid; Kamio, Eiji; Ohmukai, Yoshikage; Saeki, Daisuke; Ni, Jinren; Matsuyama, Hideto

    2015-03-01

    We investigated the effect of different membrane polymeric materials on the relationship between membrane pore size and development of membrane fouling in a membrane bioreactor (MBR). Membranes with different pore sizes were prepared using three different polymeric materials, cellulose acetate butyrate (CAB), polyvinyl butyral (PVB), and polyvinylidene fluoride (PVDF), and the development of membrane fouling in each membrane was evaluated by batch filtration tests using a mixed liquor suspension obtained from a laboratory-scale MBR. The results revealed that the optimal membrane pore size to mitigate membrane fouling differed depending on membrane polymeric material. For PVDF membranes, the degree of membrane fouling decreased as membrane pore size increased. In contrast, CAB membranes with smaller pores had less fouling propensity than those with larger ones. Such difference can be attributed to the difference in major membrane foulants in each membrane; in PVDF, they were small colloids or dissolved organics in which proteins are abundant, and in CAB, microbial flocs. The results obtained in this study strongly suggested that optimum operating conditions of MBRs differ depending on the characteristics of the used membrane.

  9. Effect of amino-terminated substrates onto surface properties of cellulose esters and their interaction with lectins

    International Nuclear Information System (INIS)

    Films of cellulose acetate butyrate (CAB) and carboxymethylcellulose acetate butyrate (CMCAB) were deposited from ethyl acetate solutions onto bare silicon wafers (Si/SiO2) or amino-terminated surfaces (APS) by means of equilibrium adsorption. All surfaces were characterized by means of ellipsometry, atomic force microscopy (AFM) and contact angle measurements. The presence of amino groups on the support surface favored the adsorption of CAB and CMCAB, inducing the orientation of most polar groups to the surface and the exposition of alkyl group to the air. Such molecular orientation caused increase of the dispersive component of surface energy (γsd) and decrease of the polar component of surface energy (γsp) of cellulose esters in comparison to those values determined for films deposited onto bare Si/SiO2 wafers. Adsorption behavior of jacalin or concanavalin A onto CAB and CMCAB films was also investigated. The adsorbed amounts of lectins were more pronounced on cellulose esters with high (γsp) and total surface energy (γst) values. - Highlights: ► Amino groups on the substrate induce the orientation of cellulose esters polar groups. ► Amino terminated substrate caused decrease of surface energy of cellulose ester films. ► Lectins adsorbed preferentially onto cellulose esters with high surface energy.

  10. A Retrospective Management Perspective on Nearly 20 Years of the Savannah River Site Citizen Advisory Board - 13078

    Energy Technology Data Exchange (ETDEWEB)

    Belencan, Helen L.; Guevara, Karen C.; Spears, Terrel J. [DOE Savannah River Site, Aiken SC (United States)

    2013-07-01

    The Department of Energy, Office of Environmental Management (DOE EM) program has invested in site specific advisory boards since 1994. These boards have served as a portal to the communities surrounding the DOE sites, provided a key avenue for public involvement, and have actively engaged in providing input and feedback that has informed clean up and priority decisions made by EM. Although the EM program has made considerable progress in completing its mission, work will continue for decades, including work at the Savannah River Site (SRS). It is reasonable to assume the advisory boards will continue in their role providing input and feedback to EM. The SRS Citizen Advisory Board (CAB) formed in 1994 and has issued 298 recommendations through September 2012. Although the effectiveness of the board is not measured by the number of recommendations issued, the recommendations themselves serve to illustrate the areas in which the CAB is particularly interested, and offer insight to the overall effectiveness of the CAB as a means for public participation in the EM decision making process. (authors)

  11. Oxidation of Tetracaine Hydrochloride by Chloramine-B in Acid Medium: Kinetic Modeling

    Directory of Open Access Journals (Sweden)

    Jayachamarajapura Pranesh Shubha

    2014-01-01

    Full Text Available Tetracaine hydrochloride (TCH is one of the potent local anaesthetics. A kinetic study of oxidation of tetracaine hydrochloride by sodium N-chlorobenzenesulfonamide (chloramine-B or CAB has been carried in HClO4 medium at 303 K. The rate shows first-order dependence on [CAB]o, shows fractional–order dependence on [substrate]o, and is self-governing on acid concentration. Decrease of dielectric constant of the medium, by adding methanol, increased the rate. Variation of ionic strength and addition of benzenesulfonamide or NaCl have no significant effect on the rate. The reaction was studied at different temperatures and the activation parameters have been evaluated. The stoichiometry of the reaction was found to be 1 : 5 and the oxidation products were identified by spectral analysis. The conjugate free acid C6H5SO2NHCl of CAB is postulated as the reactive oxidizing species. The observed results have been explained by plausible mechanism and the related rate law has been deduced.

  12. Morphological examination of the corpora lutea from pregnant bitches treated with different abortifacient regimes.

    Science.gov (United States)

    Martin, N; Höftmann, T; Politt, E; Hoppen, H O; Sohr, M; Günzel-Apel, A R; Einspanier, A

    2009-07-01

    Different abortifacient regimes in dogs were analysed for their effect on the pregnancy corpora lutea (CL), namely, prostaglandin F2a analogue cloprostenol (CLO) combined with dopamine agonist cabergoline (CAB), or progesterone (P4) receptor antagonist aglepristone (AGL). Ovaries were collected after 6-10 days of treatment during first trimester. The CL of the control-group showed strong expression of relaxin (RLX), its receptor RXFP1 and enzymes of steroid biosynthesis (HSD) with high peripheral P4-levels. Whereas RXL, RXFP1 and HSD were lowest expressed in the CLO/CAB-group with a massive degeneration of CL and their blood vessels combined with low peripheral P4-level. The AGL-group showed less extensive CL degeneration and more intensive staining of the examined factors than CLO/CAB. In summary, all examined factors are associated with normal luteal function and are useful tools to stage luteolysis. Although both treatments have the same abortive action, their sequence of events on the CL is different. PMID:19754564

  13. A Retrospective Management Perspective on Nearly 20 Years of the Savannah River Site Citizen Advisory Board - 13078

    International Nuclear Information System (INIS)

    The Department of Energy, Office of Environmental Management (DOE EM) program has invested in site specific advisory boards since 1994. These boards have served as a portal to the communities surrounding the DOE sites, provided a key avenue for public involvement, and have actively engaged in providing input and feedback that has informed clean up and priority decisions made by EM. Although the EM program has made considerable progress in completing its mission, work will continue for decades, including work at the Savannah River Site (SRS). It is reasonable to assume the advisory boards will continue in their role providing input and feedback to EM. The SRS Citizen Advisory Board (CAB) formed in 1994 and has issued 298 recommendations through September 2012. Although the effectiveness of the board is not measured by the number of recommendations issued, the recommendations themselves serve to illustrate the areas in which the CAB is particularly interested, and offer insight to the overall effectiveness of the CAB as a means for public participation in the EM decision making process. (authors)

  14. Estimating the ozone-forming potential of urban trees and shrubs

    Science.gov (United States)

    Benjamin, Michael T.; Winer, Arthur M.

    A method is presented for estimating the ozone-forming potential of biogenic hydrocarbon emissions from trees and shrubs, using the California South Coast Air Basin (SoCAB) as a case study. Hourly isoprene and monoterpenes emission rates for 308 tree and shrub species found in the SoCAB were combined with diurnal temperature and light intensity data for a representative summer day in the SoCAB to develop daily emission rates. These daily emission rates for each species were then normalized to a per tree basis using vegetation class biomass factors derived from reported leaf mass constants and tree canopy volumes. The ozone-forming potential for each of the tree and shrub species was estimated by combining the daily per tree emission rates with published maximum incremental reactivities (MIRs) for isoprene and monoterpenes. The resulting ranking of trees by ozone-forming potential can be used in tree species selection for future large-scale tree planting programs, and provides a more appropriate basis for selection than using only mass emissions of biogenic hydrocarbons.

  15. Envisioning Communications with Future Stakeholders - A Case Study Using the In-Situ Decommissioning of P-Reactor

    International Nuclear Information System (INIS)

    This paper will explore opportunities to expand the CAB's public outreach by the incorporation of technologies typically used in social networks and distance learning. Envisioning opportunities to engage next generation CAB members in public involvement will be delineated by retracing the decision process used with the in-situ decommissioning of P-Reactor at the Savannah River Site (SRS). This paper will discuss existing opportunities to enable another group of stakeholders to take part in the environmental policy decision making process regarding the inclusion of some very long lived radioactive constituents. The aim of the paper will be to locate places in the current process where alternate or parallel informational dissemination pathways could exist. These alternatives will incorporate the next generation's expectation for instantaneous information and universal ownership of hand-held communication devices. The goal of this paper is to use the present framework of CAB communications and add the components of virtual networking and distance learning in hopes of bridging the generational technology gap and extending the dialog to future stakeholders. (authors)

  16. The Reduction of Risk Perception: Consensus-Making versus Truth-Seeking

    International Nuclear Information System (INIS)

    We concluded last year that the U.S. Department of Energy's (DOE's) policy of consensus-seeking (CR) for its Citizen Advisory Boards (CAB's or Boards) promoted risk mis-perception, a lack of education, and an anti-science bias about DOE's mission to cleanup its sites. Our conclusions countered an earlier study of the CAB's funded by DOE; using only subjective data, it had concluded that consensus-seeking was an improvement in American democracy. However, our conclusion was reached by comparing decision-making at the CAB's with results in the field at the DOE sites associated with the Boards. To extend our earlier findings, we looked at recent meetings of the Board Chairs and preliminary results from the laboratory. We hypothesize that CR and the truth-seeking from majority rules (MR) reflect a tradeoff between a single world view derived from risk perceptions versus specific guidance from risk determinations. Based on both the field evidence and preliminary data from the experiment, we find that this tradeoff impacts site operations. At DOE's Hanford site, the risk perceptions of its Advisory Board (HAB) have contributed to 'gridlock'; at DOE's Savannah River Site (SRS), the specific recommendations by its Board (SAB) have contributed to accelerating cleanup. (authors)

  17. Pediatric injuries in the back of pickup trucks.

    Science.gov (United States)

    Agran, P F; Winn, D G; Castillo, D N

    1990-08-01

    Travel in the back of pickup trucks has not been adequately addressed as an occupant protection issue. This study compares injuries sustained by children riding in the back of pickup trucks with those of children riding in the cab. Data were obtained from a multihospital monitoring system and the coroner in a single urban county. The series of injured children consisted of 290 children 0 through 14 years of age, 201 of whom had been riding in the cab and 89 in the back. Age distribution of the children demonstrated that it is most frequently the 10- to 14-year-olds who travel in the back. Children riding in the back were more frequently injured in noncrash events (absence of a collision), had more ejections, had more injuries, and sustained more severe injuries as measured by the Maximum Injury Score. With increased restraint use in the cab, it is likely that even greater differentials in injury severity and patterns would be realized. Education regarding the hazards of travel in the back of pickups and stronger legislation limiting the transport of children in the back of trucks are recommended. PMID:2374274

  18. Modelling cognitive affective biases in major depressive disorder using rodents.

    Science.gov (United States)

    Hales, Claire A; Stuart, Sarah A; Anderson, Michael H; Robinson, Emma S J

    2014-10-01

    Major depressive disorder (MDD) affects more than 10% of the population, although our understanding of the underlying aetiology of the disease and how antidepressant drugs act to remediate symptoms is limited. Major obstacles include the lack of availability of good animal models that replicate aspects of the phenotype and tests to assay depression-like behaviour in non-human species. To date, research in rodents has been dominated by two types of assays designed to test for depression-like behaviour: behavioural despair tests, such as the forced swim test, and measures of anhedonia, such as the sucrose preference test. These tests have shown relatively good predictive validity in terms of antidepressant efficacy, but have limited translational validity. Recent developments in clinical research have revealed that cognitive affective biases (CABs) are a key feature of MDD. Through the development of neuropsychological tests to provide objective measures of CAB in humans, we have the opportunity to use 'reverse translation' to develop and evaluate whether similar methods are suitable for research into MDD using animals. The first example of this approach was reported in 2004 where rodents in a putative negative affective state were shown to exhibit pessimistic choices in a judgement bias task. Subsequent work in both judgement bias tests and a novel affective bias task suggest that these types of assay may provide translational methods for studying MDD using animals. This review considers recent work in this area and the pharmacological and translational validity of these new animal models of CABs. PMID:24467454

  19. Effect of amino-terminated substrates onto surface properties of cellulose esters and their interaction with lectins

    Energy Technology Data Exchange (ETDEWEB)

    Amim, Jorge [Instituto de Quimica, Universidade de Sao Paulo, Av. Prof. Lineu Prestes 748, 05508-000 Sao Paulo (Brazil); Instituto de Quimica, Universidade Federal do Rio de Janeiro, Campus Macae, Av. Aluizio Gomes da Silva 50, 27930-560, Macae (Brazil); Petri, Denise F.S., E-mail: dfsp@usp.br [Instituto de Quimica, Universidade de Sao Paulo, Av. Prof. Lineu Prestes 748, 05508-000 Sao Paulo (Brazil)

    2012-02-01

    Films of cellulose acetate butyrate (CAB) and carboxymethylcellulose acetate butyrate (CMCAB) were deposited from ethyl acetate solutions onto bare silicon wafers (Si/SiO{sub 2}) or amino-terminated surfaces (APS) by means of equilibrium adsorption. All surfaces were characterized by means of ellipsometry, atomic force microscopy (AFM) and contact angle measurements. The presence of amino groups on the support surface favored the adsorption of CAB and CMCAB, inducing the orientation of most polar groups to the surface and the exposition of alkyl group to the air. Such molecular orientation caused increase of the dispersive component of surface energy ({gamma}{sub s}{sup d}) and decrease of the polar component of surface energy ({gamma}{sub s}{sup p}) of cellulose esters in comparison to those values determined for films deposited onto bare Si/SiO{sub 2} wafers. Adsorption behavior of jacalin or concanavalin A onto CAB and CMCAB films was also investigated. The adsorbed amounts of lectins were more pronounced on cellulose esters with high ({gamma}{sub s}{sup p}) and total surface energy ({gamma}{sub s}{sup t}) values. - Highlights: Black-Right-Pointing-Pointer Amino groups on the substrate induce the orientation of cellulose esters polar groups. Black-Right-Pointing-Pointer Amino terminated substrate caused decrease of surface energy of cellulose ester films. Black-Right-Pointing-Pointer Lectins adsorbed preferentially onto cellulose esters with high surface energy.

  20. Antibiofilm activity of biosurfactant producing coral associated bacteria isolated from gulf of mannar.

    Science.gov (United States)

    Padmavathi, Alwar Ramanujam; Pandian, Shunmugiah Karutha

    2014-12-01

    Coral Associated Bacteria (CAB) (N = 22) isolated from the mucus of the coral Acropora digitifera were screened for biosurfactants using classical screening methods; hemolysis test, lipase production, oil displacement, drop collapse test and emulsifying activity. Six CAB (U7, U9, U10, U13, U14, and U16) were found to produce biosurfactants and were identified by 16S ribosomal RNA gene sequencing as Providencia rettgeri, Psychrobacter sp., Bacillus flexus, Bacillus anthracis, Psychrobacter sp., and Bacillus pumilus respectively. Their cell surface hydrophobicity was determined by Microbial adhesion to hydrocarbon assay and the biosurfactants produced were extracted and characterized by Fourier Transform Infrared spectroscopy. Since the biosurfactants are known for their surface modifying capabilities, antibiofilm activity of positive isolates was evaluated against biofilm forming Pseudomonas aeruginosa ATCC10145. Stability of the active principle exhibiting antibiofilm activity was tested through various temperature treatments ranging from 60 to 100 °C and Proteinase K treatment. CAB isolates U7 and U9 exhibited stable antibiofilm activity even after exposure to higher temperatures which is promising for the development of novel antifouling agents for diverse industrial applications. Further, this is the first report on biosurfactant production by a coral symbiont. PMID:25320434

  1. Development of torodial magnetic thermometry to study new phenomena associated with the superfluid transition in liquid 4He

    International Nuclear Information System (INIS)

    A new type of paramagnetic susceptibility thermometry called toroidal magnetic thermometry (TMT) has been developed. These TMT thermometers have a thermal resolution of five nanoKelvin near the 4He superfluid transition temperature Tλ = 2.172K, making TMT roughly a factor of fifty times better in resolution than conventional germanium resistance thermometry which is commercially available. The dramatic improvement in thermal resolution provided by TMT has been used to observe new phenomena associated with the superfluid transition in pure liquid 4He. Such phenomena include a component of the thermal boundary (Kapitza) resistance RK which is singular at the superfluid transition temperature Tλ. In addition to the boundary effects described above, these TMT thermometers have been used to detect the depression of Tλ be a heat current Q flowing through the liquid helium. When these values of ΔTλ(Q) were used to calculate the depression of the superfluid density Δρs(Q) the results agreed well with a prediction based on the theory of Ginzburg and Pitaevskii. The calibration of the TMT thermometers provide high-resolution measurements of the a.c. paramagnetic susceptibility of their magnetic salt: Copper ammonium bromide (CAB). These calibration parameters, together with power dissipation data near the CAB Curie temperature Tc = 1.79K, provide information on the magnetic critical behavior of this nearly ideal Heisenberg ferromagnet. Throughout the detailed description of the TMT design, aspects of the CAB magnetic critical phenomena are discussed

  2. Evaluation of Various Spectral Inputs for Estimation of Forest Biochemical and Structural Properties from Airborne Imaging Spectroscopy Data

    Science.gov (United States)

    Homolová, L.; Janoutová, R.; Malenovský, Z.

    2016-06-01

    In this study we evaluated various spectral inputs for retrieval of forest chlorophyll content (Cab) and leaf area index (LAI) from high spectral and spatial resolution airborne imaging spectroscopy data collected for two forest study sites in the Czech Republic (beech forest at Štítná nad Vláří and spruce forest at Bílý Kříž). The retrieval algorithm was based on a machine learning method - support vector regression (SVR). Performance of the four spectral inputs used to train SVR was evaluated: a) all available hyperspectral bands, b) continuum removal (CR) 645 - 710 nm, c) CR 705 - 780 nm, and d) CR 680 - 800 nm. Spectral inputs and corresponding SVR models were first assessed at the level of spectral databases simulated by combined leaf-canopy radiative transfer models PROSPECT and DART. At this stage, SVR models using all spectral inputs provided good performance (RMSE for Cab images of the spruce site produced unacceptably overestimated values, only the beech site results were analysed. The best performance for the Cab estimation was found for CR bands in range of 645 - 710 nm, whereas CR bands in range of 680 - 800 nm were the most suitable for LAI retrieval. The CR transformation reduced the across-track bidirectional reflectance effect present in airborne images due to large sensor field of view.

  3. Alterations in chlorophyll a/b binding proteins in Solanaceae cybrids.

    Science.gov (United States)

    Babiychuk, E; Schantz, R; Cherep, N; Weil, J H; Gleba, Y; Kushnir, S

    1995-12-20

    In this study we have constructed a number of plants (cybrids), in which the nuclear genome of Nicotiana plumbaginifolia is combined with the plastome of Atropa belladonna, or the nuclear genome of N. tabacum with plastomes of Lycium barbarum, Scopolia carniolica, Physochlaine officinalis or Nolana paradoxa. Our biochemical and immunological analyses prove that in these cybrids the biogenesis of the chlorophyll a/b binding proteins (CAB) of the light harvesting complex II (LHCII) is altered. Besides normal sized CAB polypeptides of 27, 25.5 and 25 kDa, which become less abundant, the cybrids analyzed have additional polypeptides of 26, 24.5 and 24 kDa. Direct protein micro-sequencing showed that at least two truncated 26 kDa CAB polypeptides in plant cells containing a nucleus of N. plumbaginifolia and plastids of A. belladonna are encoded by the type 1 Lhcb genes. These polypeptides are 11-12 amino acids shorter at the N-terminus than the expected size. Based on the available data we conclude that the biogenesis of the LHCII in vivo may depend on plastome-encoded factor(s). These results suggest that plastome-encoded factors that cause specific protein degradation and/or abnormal processing might determine compartmental genetic incompatibility in plants. PMID:8544830

  4. Alteration of gene expression in Pisum sativum tissue cultures caused by the free radical-generating agent 2,2`-azobis (2-amidinipropane) dihydrochloride

    Energy Technology Data Exchange (ETDEWEB)

    Henkow, L. [Sveriges Lantbruksuniv., Inst. foer Vaextfoeraedling, Uppsala (Sweden); Strid, Aa.; Rydstroem, J. [Goeteborgs Univ. och Chalmers Tekniska Hoegskola, Inst. foer Biokemi och Biofysik, Goeteborg (Sweden); Berglund, T.; Ohlsson, A.B. [Kungliga Tekniska Hoegskolan, Inst. foer Biokemi och biokemisk Teknologi, Stockholm (Sweden)

    1996-04-01

    Root-differentiated tissue cultures (PS-R) from Pisum sativum (cv. Greenfeast) were exposed to a 5 mM solution of the free radical-generating compound 2,2`-azobis (2-amidinopropane) dihydrochloride (AAPH). The levels of mRNA transcripts for two genes were examined: chs2, encoding a chalcone synthase isozyme, and cab, encoding the chlorophyll a/b-binding protein of the light-harvesting antenna complex. In light-grown PS-R, cab mRNA transcript levels decreased to 14% of controls after 6 h of exposure, whereas chs2 mRNA levels increased 50-fold. In dark-grown PS-R, chs2 mRNA transcripts increased by 40-fold compared with the controls. Glutathione determination inlight-grown PS-R showed no substantial difference in total glutathione (GSH{sub tot}), whereas oxidized glutathione (GSSG) increased by 66% after 12 h of exposure. However, in dark-grown PS-R a decrease in both GSH{sub tot} and GSSG after 6 h was followed by an increase of about 70%, as compared with the controls, after 12 h of exposure. In conclusion AAPH generated oxidative stress, reflected in changed glutathione levels and induced expression of the chs2 gene of the flavonoid biosynthetic pathway and also caused a decreased level of mRNA for the photosynthetic cab gene. (au) 39 refs.

  5. Suplemento múltiplo com ionóforos para novilhos em pasto: consumo, fermentação ruminal e degradabilidade in situ

    Directory of Open Access Journals (Sweden)

    M.H.F Mourthe

    2011-02-01

    Full Text Available Avaliou-se o efeito do suplemento múltiplo com ionóforos sobre o consumo, a fermentação ruminal e a degradabilidade in situ da matéria seca da forragem. Utilizaram-se cinco novilhos Holandês x Zebu fistulados no rúmen, com peso vivo médio de 350kg, em delineamento em quadrado latino. Os tratamentos foram: suplementação múltipla sem ionóforos (CONT; suplementação múltipla com 100mg/cab/dia de monensina (M100; suplementação múltipla com 200mg/cab/dia de monensina (M200; suplementação múltipla com 100mg/cab/dia de lasalocida (L100; e suplementação múltipla com 200mg/cab/dia de lasalocida (L200. O uso de ionóforos no suplemento não influenciou o consumo de forragem, que foi, em média, 7,24kg MS/dia. A presença de ionóforos resultou em ligeiro aumento do pH ruminal em relação à ausência desses aditivos (P<0,05. Houve diferença na concentração do N-NH3 apenas para os teores de ionóforos em que 200mg/cab/dia reduziu a quantidade de N-NH3. As concentrações de acetato, propionato e butirato não foram influenciadas pela inclusão, pelo tipo ou pelos teores de ionóforos. A fração solúvel média (A da Brachiaria decumbens foi igual a 22%, e a fração insolúvel potencialmente degradável média (B igual a 65%, resultando em degradação potencial média de 87%. A taxa de degradação média (c foi de 0,03/hora. Os ionóforos não alteraram a degradação in situ da matéria seca

  6. Avaliação epidemiológica, clínica, anatomopatológica e etiológica de surtos de ataxia em cabritos e cordeiros

    Directory of Open Access Journals (Sweden)

    Santos Néria Vania Marcos dos

    2006-01-01

    Full Text Available Nos anos de 2001 e 2002, 46 cabritos (CAB e 35 cordeiros (COR de uma propriedade do agreste do Estado de Pernambuco foram acometidos por ataxia enzoótica (AE de forma tardia. Houve aumento da incidência do 1o ano (46,3% - CAB; 24,2% COR para o ano subseqüente (100% - CAB e COR. Somente no ano de 2001, houve maior incidência em CAB (P<0,002 que nos COR. Todos os animais acometidos sucumbiram, com exceção de um CAB e um de COR. O quadro clínico variou de acordo com a idade em que surgiram os sintomas, ou seja, de 30 a 45 dias os animais manifestaram paralisia dos membros anteriores e posteriores, acompanhada de espasticidade muscular e morte; com mais de 45 dias, ocorreu paralisia flácida ou espástica apenas dos membros posteriores e morte; somente os cabritos com menos de 45 dias apresentaram movimentos verticais de cabeça. As lesões histopatológicas evidenciadas foram: degeneração axonal, esferóides, gliose e dismielinização no segmento ventral e lateral da medula espinhal. Nos animais com menos de 45 dias, essas lesões foram evidentes na região cervical e nos animas mais velhos na região lombar. Apenas nos cabritos foi constatada lesão degenerativa no cerebelo. A dieta oferecida ao rebanho continha quantidades adequadas de cobre, porém os animais acometidos por AE apresentaram baixos teores de cobre no fígado (45,8mg kg-1 MS. Os elementos antagonizantes do cobre, Mo, S, e Zn, estavam normais, com exceção do ferro, que estava em alta concentração tanto no solo (8600mg kg-1 quanto nos alimentos (284mg kg-1. O excesso de ingestão de ferro sugere ter provocado a carência de cobre nos animais.

  7. 气调箱贮藏甜樱桃品质变化研究%Changes of Qualites in Sweet Cherry Stored with CA Box

    Institute of Scientific and Technical Information of China (English)

    王宝刚; 李文生; 冯晓元; 石磊; 杨媛; 张开春

    2011-01-01

    以‘美早’和‘萨米脱’甜樱桃为试材,研究了气调箱保鲜处理对甜樱桃果实贮藏期间品质变化的影响.结果显示,2个品种甜樱桃贮藏过程中,气调箱内CO2浓度基本维持在12%~15%,O2浓度不低于6%;气调箱处理甜樱桃果实硬度显著高于对照果实;气调箱处理轻微降低了可溶性固形物的含量,但却保持了果实较高的可滴定酸以及维生素C含量.气调处理最明显的效果就是降低了甜樱桃果实的腐烂率.2个品种相比较,‘萨米脱’的腐烂率要远低于美早,耐贮性较好.2个品种果实经0℃贮藏60天后仍具有较好的感官品质,并可以保证3天的常温货架期.综上所述,气调箱能够保持果实较好的贮藏品质,可以用于贮运甜樱桃果实,具有很好的推广前景.%Sweet cherry fruit {Prunus avium L. Cv. Tieton and cv. Summit) were held into controlling atmosphere box (CAB), and then stored at (0 ± 0.5)t. The postharvest qualities of sweet cherry fruit were investigated at interval. Results showed that the carbon dioxide concentration in CAB were 12%-15%, and 6% higher O2 concentration. Firmness in fruit stored in CAB was higher than those in control. CAB treatment decreased the soluble solids content of sweet cherry fruit, but maintained the higher tritratable acidity and Vc content in contrast to control. CAB treatment inhibited significantly the decay incidence of sweet cherry fruit during storage and shelf-life. The lower decay incidence was found in 'Summit' fruit compared with 'Tieton' fruit. The sweet cherry fruit treated by CAB still had good sensory quality significantly after 60 days of storage and 3 days of shelf-life at ambient temperature. In general, CAB can keep better qualities, and be suitable for transportation and sales industry of sweet cherry fruit.

  8. Enfoques metodológicos para identificar y caracterizar la investigación mexicana en química en bases de datos bibliográficas Methodological approaches to identify and describe Mexican chemistry research in bibliographic databases

    Directory of Open Access Journals (Sweden)

    Yoscelina Hernández García

    2013-04-01

    Full Text Available Las distintas visiones que dan las diferentes fuentes de información con respecto a un campo de investigación en particular es un fenómeno conocido en los estudios bibliométricos y cienciométricos. El presente artículo tiene por propósito entender el impacto de las fuentes de información en la identificación y la caracterización de un campo científico en un contexto particular: la química en México. No se trata de comparar la producción científica en este campo extraída de varias bases de datos bibliográficas, sino de partir de una metodología original que consiste en construir estrategias de búsqueda adecuadas para cada fuente y procesos de normalización, análisis y visualización de los resultados, mostrar que la definición del campo científico estudiado depende de las fuentes de información usadas. Se usaron fuentes nacionales e internacionales especializadas, o relacionadas con las ciencias químicas, así como recursos multidisciplinarios, a saber Web of Science (WoS, Chemical Abstracts Service (CAS, PERIÓDICA y CAB Abstracts (CAB en el periodo de 2000-2004. Los resultados apuntan al impacto de las especificidades de la estructura de cada base de datos en los resultados de las búsquedas; en PERIÓDICA, la producción se concentra en 37 revistas (44% mientras que los trabajos en revistas internacionales se encuentran repartidas en un total de 1559 publicaciones (WoS, 188 (CAB y 1640 (CAS.The varying visions of a particular research field in diverse information sources are a recognized phenomenon in bibliometric and scientometric studies. The purpose of this paper is to provide an understanding of the impact of using distinct information sources for the identification and description of a scientific field in a specific context, in this instance the field of chemistry in Mexico. We use both international and national sources specializing in or related to chemistry, as well as suitable multidisciplinary services

  9. Biomarker characterization of the record of the OAE1a (early Aptian) in Betic and Cantabrian basins (Spain)-Sedimentary implications

    Science.gov (United States)

    Quijano, María. Luisa; Castro, José Manuel; Pancost, Richard D.; de Gea, Ginés. A.; Najarro, María.; Aguado, Roque; Rosales, Idoia; Martín-Chivelet, Javier

    2010-05-01

    Molecular analyses of sedimentary organic matter are powerful tools in assessing the origin of organic matter and its thermal maturity as well as constraining ancient environmental conditions, such as as marine productivity, anoxia in bottom waters or the photic zone and sea surface temperatures. This communication presents the study of four sections recording the OAE1a (early Aptian) in Spain, which are located in two broad basins respectively located in the South and the North of Iberia: the Southern Iberian Palaeomargin (Carbonero - CAB, La Frontera - XF and Cau - CAU sections) and the Cantabrian Basin (Puente Nansa - PN section). These sections represent depositional settings ranging from platform (CAU, PN) to pelagic environments (CAB, XF). C-isotope profiles and biostratigraphic data are used to define the interval corresponding to the OAE 1a. Here we focus on the biomarker composition of the organic-rich facies, and the integration of these data with the sedimentology, stratigraphy and paleogeography. The study has been based mainly upon the analysis of samples with Gas Chromatography-Mass Spectrometry (GCMS). Four main groups of compounds are present in all sections: n-alkanes, isoprenoids, hopanes and steranes. n-Alkanes and isoprenoids (pristane and phytane) are dominant in most samples. To facilitate interpretation of these distributions, we have calculated the TAR (terrestrial aquatic ratio derived from the ratio of long to short chain compounds) and also the OEP (odd over even predominance of n-alkanes). The ratio of pristane to phytane and various isoprenoid/n-alkanes ratios have also been calculated. The hopanes are represented by a range of C27 to C35 components, with the specific isomers varying amongst the sections due to differences in thermal maturity. Steranes occur as a range of C27, C28 and C29 isomers, whereas diasteranes only occur in the most thermally mature section (CAB). Other compounds of interest include gammacerane and dinosterane

  10. Finding the Public Voice: A Few Observations After Experience on the SRS Citizens Advisory Board - 12226

    International Nuclear Information System (INIS)

    This Paper reflects my views on some of the difficulties and successes in seeking and reflecting the opinions and input of the typical citizen relative to the Savannah River Site (SRS) cleanup programs. These views are based on four years of membership on the SRS Citizens Advisory Board (CAB). The Savannah River Site Citizens Advisory Board was established by Department of Energy- Environmental Management in 1994 with the goal of improving cleanup decisions by reflecting priorities and concerns of stakeholders and generally improving communication with the public, particularly in the areas most impacted by site operations. The SRS CAB has been a successful venture and has had a notable record of accomplishments with approximately 285 recommendations over its 17-year history. Many of these recommendations have been very specific and have impacted Site priorities on many issues of concern to the public. However, attaining this success and truly reflecting the views of the typical citizen is a difficult proposition. This concept begs such questions as: where do you get the input? how do you get these views? and how do you know when you've gotten it right? As a Board we have had to deal with groups who seem to have a bias either in favor of or strongly opposed to certain cleanup actions or other groups who have a total focus on a single topic such as jobs. It is our role to ensure that a balanced approach is adopted which reflects the sentiments of the general public. After some four years experience on the Board I have formulated a few ideas that should make the Board one that more completely reflects public sentiments and makes useful thoughtful input. Therefore, this paper looks at the manner and difficulty of seeking input and generally communicating with the public while offering some views on how to improve the process. The Citizens Advisory Board was envisioned as a body of private citizens who looked at cleanup activities of the Site and reflected the public

  11. Experimental evaluation of venosclerosis of aortocoronary femoral vein bypass graft in control and aspirin-persantine-treated dogs: Correlation with atherosclerosis

    International Nuclear Information System (INIS)

    Coronary artery bypass surgery (CABS) improves the quality of life, decreases myocardial ischemia and angina pectoris or chest pain, and increases patient survival in a selected group of patients with coronary artery disease who do not improve upon medical treatment. This group includes patients with chest pain and more than 50% narrowing of the luminal diameter of the left main coronary artery. CABS has been performed about 500,000 times in the United States during the last 15 years in 600 hospitals. Presently, about 100,000 CABS are done every year at an expense of 2 billion dollars. A major limitation of this procedure is the high frequency of occlusion of the vein graft secondary to thrombosis or intimal proliferation or both. Our knowledge about arteriosclerosis and vascular occlusion is based on models using arteries. Little is known on the behavior of veins when transporting arterial blood. There is evidence that a vein graft due to its inherent environment and damage during harvesting and implantation undergoes biochemical and pathological changes similar to atherosclerosis. The authors used the dog model to study the pathobiology of grafted femoral veins in the aortocoronary position, although they realized that dogs are not prone to diet-induced arterosclerosis, like rabbits, pigs, and monkeys. The effect of aspirin-Persantine on thrombotic occlusion was studied with 111In-labeled platelets and 125I-labeled fibrinogen, and cholesterol uptake and de-endothelialization was evaluated, the extracellular space was measured with 82Br-bromide and edema was evaluated by transmission electron microscopy. Attempts were made to correlate the findings in atherosclerosis with those of vein-graft sclerosis (venosclerosis)

  12. The beta-adrenergic blocker carvedilol restores L-type calcium current in a myocardial infarction model of rabbit

    Institute of Scientific and Technical Information of China (English)

    LI Xia; HUANG Cong-xin; JIANG Hong; CAO Feng; WANG Teng

    2005-01-01

    Background Carvedilol, an antagonist of α1- and β-adrenergic receptors, has shown efficacy in reducing all-cause death and arrhythmia death for ischemic heart disease and congestive heart failure in several large-scale trials. It has been found to prevent ventricular remodeling, and recently was reported to reverse down-regulation of Na+ channel in a chronic heart failure model. This study was conducted to investigate whether carvedilol could reverse the ion remodeling in a myocardial infarction model of rabbit.Methods After the procedure of coronary ligation, animals were randomized to placebo or carvedilol treatment (5 mg/kg). Action potentials, L-type calcium current (Ica L) and the effect of isoproterenol stimulation on Ica L were measured using whole-cell patch method. Evaluation of the expression of calcium channel subunits was carried out by RT-PCR and Western blot. Results The results indicate that mean peak Ica L densities (pA/pF) at +10 mV was reduced in postinfarction myocytes (5.33±0.45, n=25) compared to sham myocytes (6.52±0.21, n=20). Treatment of myocardial infarction rabbits with carvedilol could restore it partially (5.91±0.39, n=20, P<0.05). However, steady-state activation parameters were similar in three groups. With stimulation by isoproterenol (1 μmol/L) Ica L increased in all three groups, but the increase was smaller in postinfarction myocytes. mRNA levels of calcium channel subunit CaA1 gene was decreased but CaB2a, CaB2b and CaB3 mRNA levels did not change after MI. Corresponding change in CaA1 protein was also observed. Conclusions The results demonstrate that carvedilol restores Ica L density and reverse the downregulation of CaA1 postinfarction.

  13. Investigating the usefulness of satellite-derived fluorescence data in inferring gross primary productivity within the carbon cycle data assimilation system

    Science.gov (United States)

    Koffi, E. N.; Rayner, P. J.; Norton, A. J.; Frankenberg, C.; Scholze, M.

    2015-07-01

    Simulations of carbon fluxes with terrestrial biosphere models still exhibit significant uncertainties, in part due to the uncertainty in model parameter values. With the advent of satellite measurements of solar induced chlorophyll fluorescence (SIF), there exists a novel pathway for constraining simulated carbon fluxes and parameter values. We investigate the utility of SIF in constraining gross primary productivity (GPP). As a first test we assess whether SIF simulations are sensitive to important parameters in a biosphere model. SIF measurements at the wavelength of 755 nm are simulated by the Carbon-Cycle Data Assimilation System (CCDAS) which has been augmented by the fluorescence component of the Soil Canopy Observation, Photochemistry and Energy fluxes (SCOPE) model. Idealized sensitivity tests of the SCOPE model stand-alone indicate strong sensitivity of GPP to the carboxylation capacity (Vcmax) and of SIF to the chlorophyll AB content (Cab) and incoming short wave radiation. Low sensitivity is found for SIF to Vcmax, however the relationship is subtle, with increased sensitivity under high radiation conditions and lower Vcmax ranges. CCDAS simulates well the patterns of satellite-measured SIF suggesting the combined model is capable of ingesting the data. CCDAS supports the idealized sensitivity tests of SCOPE, with SIF exhibiting sensitivity to Cab and incoming radiation, both of which are treated as perfectly known in previous CCDAS versions. These results demonstrate the need for careful consideration of Cab and incoming radiation when interpreting SIF and the limitations of utilizing SIF to constrain Vcmax in the present set-up in the CCDAS system.

  14. Constitutive, light-responsive and circadian clock-responsive factors compete for the different l box elements in plant light-regulated promoters.

    Science.gov (United States)

    Borello, U; Ceccarelli, E; Giuliano, G

    1993-10-01

    The l box is a conserved regulatory motif which is found upstream of plant genes (rbcS, cab and nia) whose transcription is regulated by light and the circadian clock. Gel retardation and UV cross-linking assays were used to resolve two different groups of I box binding factors (IBFs) in tomato nuclear extracts. Active components of the first group (IBF-1) recognize the l box of the light-responsive rbcS promoter; one factor within this group, IBF-1a, also recognizes the adjacent G box, which has been shown previously to bind a different class of plant transcription factors, the G box binding factors (GBFs). To the limit of experimental resolution, IBF-1a and GBF compete for the same nucleotides on the G box. Nevertheless, these two activities are biochemically and immunologically distinct. The relative abundance of IBF-1a shows a vast decrease in dark-adapted plants. Factors in the second group (IBF-2), recognize the l box of the nia promoter, which is regulated both by light and the circadian clock; one factor within this group, IBF-2a, also binds the l box of a second promoter showing similar regulation, the cab promoter. The IBF-2a binding sites on the cab and nia promoters show extensive homology to a circadian clock-responsive promoter element from wheat. The abundance of IBF-2a is diurnally regulated and shows a dramatic induction around the onset of the light period. Transfer of the plants in continuous darkness demonstrates that this induction is under the control of a circadian clock.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8252065

  15. The influence of secondary processing on the structural relaxation dynamics of fluticasone propionate.

    Science.gov (United States)

    Depasquale, Roberto; Lee, Sau L; Saluja, Bhawana; Shur, Jagdeep; Price, Robert

    2015-06-01

    This study investigated the structural relaxation of micronized fluticasone propionate (FP) under different lagering conditions and its influence on aerodynamic particle size distribution (APSD) of binary and tertiary carrier-based dry powder inhaler (DPI) formulations. Micronized FP was lagered under low humidity (LH 25 C, 33% RH [relative humidity]), high humidity (HH 25°C, 75% RH) for 30, 60, and 90 days, respectively, and high temperature (HT 60°C, 44% RH) for 14 days. Physicochemical, surface interfacial properties via cohesive-adhesive balance (CAB) measurements and amorphous disorder levels of the FP samples were characterized. Particle size, surface area, and rugosity suggested minimal morphological changes of the lagered FP samples, with the exception of the 90-day HH (HH90) sample. HH90 FP samples appeared to undergo surface reconstruction with a reduction in surface rugosity. LH and HH lagering reduced the levels of amorphous content over 90-day exposure, which influenced the CAB measurements with lactose monohydrate and salmeterol xinafoate (SX). CAB analysis suggested that LH and HH lagering led to different interfacial interactions with lactose monohydrate but an increasing adhesive affinity with SX. HT lagering led to no detectable levels of the amorphous disorder, resulting in an increase in the adhesive interaction with lactose monohydrate. APSD analysis suggested that the fine particle mass of FP and SX was affected by the lagering of the FP. In conclusion, environmental conditions during the lagering of FP may have a profound effect on physicochemical and interfacial properties as well as product performance of binary and tertiary carrier-based DPI formulations. PMID:25398478

  16. A Contrastive Genre Analysis of Chinese and American University Ad-mission Brochures

    Institute of Scientific and Technical Information of China (English)

    占小海; 许云柯

    2015-01-01

    This study mainly uses the move and step analysis to conduct a contrastive genre analysis on the selected 20 Chinese ad⁃mission brochures (CABs) and 20 American admission brochures (AABs). Differences in moves, move sequences and step arrange⁃ments have revealed themselves in this comparison. Firstly, Chinese university admission brochures cast more focus on basic infor⁃mation about the university, the application procedure and admission criteria, while American universities, besides offering such in⁃formation, also emphasize the promotional function of the admission brochures. They use appealing and creative moves to commer⁃cially‘sell’advantages of the university to the potential applicants. Secondly, based on Kress&van Leeuwen’s visual grammar symbolic meaning, images and colors in admission brochures are also explored and analyzed as language. For one thing, after count⁃ing the frequency of the four categories of images, namely portrait, campus scenery, campus life pictures and graphs, it is found that, compared with CABs, AABs have a highly more obvious tendency in using images. The images are used as an effective tool to increase the sense of credibility, identity-recognition, attract reader’s attention, and help understanding, making the facts and in⁃formation more intuitive. For another thing, the main colors used in the brochures are yet another noticeable feature. Especially in American brochures, universities tend to use their‘traditional colors’in the brochure to achieve a sense of consistency. Some Chi⁃nese brochures also follow this promotional strategy, yet a large percentage of them do not use any recognizable colors other than the printed black and white. Based on these differences, suggestions are put forward from perspectives including choice of moves and steps to improve the quality of CABs, hopefully raising their acceptance in the international level.

  17. Effect of the size of silica nanoparticles on wettability and surface chemistry of sol–gel superhydrophobic and oleophobic nanocomposite coatings

    Energy Technology Data Exchange (ETDEWEB)

    Lakshmi, R.V., E-mail: lakshmi_rv@nal.res.in; Bera, Parthasarathi; Anandan, C.; Basu, Bharathibai J.

    2014-11-30

    Highlights: • Superhydrophobic coatings from Cab-O-Sil EH5 and M5 particles in MTEOS sol. • Particle size of Cab-O-Sil influenced its optimum concentration in coating. • FAS-13 modification improved the oleophobicity of the coating. • Coating surface exhibited porous structure with nanovoids and microscale bumps. • Coatings with Cab-O-Sil EH5 retained water repelling property for a long time. - Abstract: Superhydrophobic sol–gel nanocomposite coatings have been fabricated by incorporating silica nanoparticles with different particle sizes separately in an acid-catalyzed sol of methyltriethoxysilane (MTEOS). Water contact angle (WCA) of the coatings increased with increase in the concentration of silica nanoparticles in both the cases. The coatings became superhydrophobic at an optimum silica concentration. The water repellency was further improved by the addition of fluoroalkylsilane (FAS). The optimum silica concentration was found to depend on the size of silica nanoparticles and FAS content and the coatings exhibited WCA of about 160° and water sliding angle (WSA) of <2°. FAS addition also improved the oleophobicity of the coatings. The coatings exhibited oil-repellency with a lubricant oil contact angle of 126° and ethylene glycol contact angle of 153.3°. Surface morphology of the coatings analyzed using field emission scanning electron microscopy (FESEM) showed a rough surface with microscale bumps and nanoscale pores. XPS was used to study the surface composition of the coatings. The superhydrophobic property of the coatings was due to the synergistic effect of surface chemistry and surface microstructure and can be explained using Cassie-Baxter model.

  18. Effect of the size of silica nanoparticles on wettability and surface chemistry of sol–gel superhydrophobic and oleophobic nanocomposite coatings

    International Nuclear Information System (INIS)

    Highlights: • Superhydrophobic coatings from Cab-O-Sil EH5 and M5 particles in MTEOS sol. • Particle size of Cab-O-Sil influenced its optimum concentration in coating. • FAS-13 modification improved the oleophobicity of the coating. • Coating surface exhibited porous structure with nanovoids and microscale bumps. • Coatings with Cab-O-Sil EH5 retained water repelling property for a long time. - Abstract: Superhydrophobic sol–gel nanocomposite coatings have been fabricated by incorporating silica nanoparticles with different particle sizes separately in an acid-catalyzed sol of methyltriethoxysilane (MTEOS). Water contact angle (WCA) of the coatings increased with increase in the concentration of silica nanoparticles in both the cases. The coatings became superhydrophobic at an optimum silica concentration. The water repellency was further improved by the addition of fluoroalkylsilane (FAS). The optimum silica concentration was found to depend on the size of silica nanoparticles and FAS content and the coatings exhibited WCA of about 160° and water sliding angle (WSA) of <2°. FAS addition also improved the oleophobicity of the coatings. The coatings exhibited oil-repellency with a lubricant oil contact angle of 126° and ethylene glycol contact angle of 153.3°. Surface morphology of the coatings analyzed using field emission scanning electron microscopy (FESEM) showed a rough surface with microscale bumps and nanoscale pores. XPS was used to study the surface composition of the coatings. The superhydrophobic property of the coatings was due to the synergistic effect of surface chemistry and surface microstructure and can be explained using Cassie-Baxter model

  19. Exposure to particulates, microorganisms, beta(1-3)-glucans, and endotoxins during soybean harvesting.

    Science.gov (United States)

    Roy, Chad J; Thorne, Peter S

    2003-01-01

    Sclerotinia sclerotiorum is an emerging fungal pathogen affecting soybeans in the United States. In response to its emergence, exposures to particulates, bioaerosols, endotoxins, S. sclerotiorum, and beta(1-3)-glucans were characterized during soybean harvesting. Air sampling was performed on soybean harvesters (combines) and on the farmers in closed cabs as personal samples during harvesting at 17 farms in 1997 and repeated at 15 in 1998. S. sclerotiorum infestation was evident in the fields at 8 of the sites (44%). The geometric mean concentrations (and geometric standard deviations) measured on the combines in 1998 were as follows: total dust, 11.9 (2.8) mg/m(3); inhalable dust 11.7 (6.4) mg/m(3); and beta(1-3)-glucans, 5027 (7) ng/m(3). Values for the personal samples in 1998 were as follows: total dust, 1.2 (6.7) mg/m(3); inhalable dust, 1.1 (5.3); and beta(1-3)-glucans, 674 (9) ng/m(3). These concentrations were two- to threefold higher than in the previous year. Ambient endotoxin concentrations were 4438 EU/m(3) in Year I and 459 EU/m(3) in Year II. Particle size distribution measurements on the combines yielded mass median aerodynamic diameters of 6.6 microm on the combine and 4.0 microm inside the combine cab. Closed combine cabs provided an average workplace protection factor of 11.7 for total dust. Nevertheless, personal exposures to organisms inside combine cabins ranged from 3.6 x 10(4) to 4.0 x 10(8) organisms/m(3). These data indicate the potential exists for high exposures to organic dust and bioaerosols during soybean harvesting. PMID:12908864

  20. Identification of antiviralrelevant genes in the cultured fish cells induced by UV-inactivated virus

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    UV-inactivated grass carp hemorrhage virus (GCHV) can induce high titer of interferon in cultured CAB (crucian carp (Carassius auratus L.) blastulae) cells, and thus defend host cells against the virus invasion. The mechanism is proposed that an antiviral state should be established in the host cells by activating expression of a set of antivi-ral-relevant genes. In this study, suppressive subtractive hy-bridization is applied to constructing a subtracted cDNA library with mRNAs isolated from UV-inactivated GCHV infected and mock-infected CAB cells. 272 differential cDNA fragments are identified by both PCR and dot blot from the subtractive cDNA library. Sequencing analysis reveals 69 genes, including 46 known gene homologues, and 23 unknown putative genes. The known genes include the genes involved in interferon signaling pathways, such as Stat1 and Jak1, the antiviral genes, such as Mx and Viperin, and a set of interferon-stimulated genes observed in mammalian cells. Most of the unknown putative genes contain AU-rich ele-ment in their sequences. Differential expressions of these genes are further confirmed by virtual Northern blot and RT-PCR. The data imply that UV-inactivated GCHV is not only able to induce production of interferon in the infected CAB cells, but also leads to the expression of a series of antiviral-relevant genes or immune-relevant genes, and therefore reveals that the signaling pathway of interferon system and antiviral mechanism in fish are similar to those in mammals.

  1. Quantifying the Stress Responses of Brassica Rapa Genotypes, With Experimental Drought in Two Nitrogen Treatments

    Science.gov (United States)

    Hickerson, J. L.; Pleban, J. R.; Mackay, D. S.; Aston, T.; Ewers, B. E.; Weinig, C.

    2014-12-01

    In a greenhouse study designed to quantify and compare stress responses of four genotypes of Brassica rapa, broccolette (bro), cabbage (cab), turnip (tur), and oil, leaf water potential and net CO2 assimilations were measured. Individuals from each genotype, grown either with high or low nitrogen, were exposed to experimental drought of the same duration. One hypothesis was that the genotypes would differ significantly in their responses to periodic drought. The other hypothesis was that the nitrogen treatment versus no nitrogen treatment would play a significant role in the stress responses during drought. It would be expected that the nitrogen treated would have greater dry leaf mass. A LI-6400 XT portable photosynthesis system was used to obtain A/Ci curves (net CO2 assimilation rate versus substomatal CO2) for each treatment group. Predawn and midday water potentials were obtained throughout the hydrated and drought periods using a Model 670 pressure chamber. The dry leaf mass was significantly greater among the high nitrogen group versus the low nitrogen group for each genotype. Nitrogen and genotype were both determinants in variation of water potentials and net CO2 assimilation. Bro and cab genotypes with high nitrogen showed the highest net CO2 assimilation rates during hydration, but the assimilation rates dropped to the lowest during droughts. The water potentials for bro and cab were lower than values for tur and oil. Nitrogen treated genotypes had lower water potentials, but higher net CO2 assimilation rates. Bayesian ecophysiological modeling with the TREES model showed significant differences in trait expression, quantified in terms of differences in model parameter posteriors, among the four genotypes.

  2. Butyl acetate synthesis using immobilized lipase in calcium alginate beads

    International Nuclear Information System (INIS)

    The esterification reaction of acetic acid and n-butanol using immobilized lipase encapsulated in calcium alginate beads (Lipase - CAB) and in chitosan coated calcium alginate beads (Lipase-CCAB) in n-hexane under mild reaction conditions were studied. Effects of temperature and substrate concentration (acetic acid and n-butanol) using Lipase - CAB, Lipase - CCAB and free lipase on the esterification reaction and their thermal stability towards esterification reaction were investigated. Results of temperature studies showed that the butyl acetate conversion increased with increase of temperature and reached the highest yield of about 70% around 50 degree Celsius for both immobilized systems but the yield of product catalyzed by free enzyme decreased as temperature was increased. Thermal stabilities studies showed that the Lipase-CCAB and Lipase-CAB were stable throughout the temperature range of 30-60 degree Celsius. However, free lipase became less stable at temperatures higher than 50 degree Celsius. The substrates, n-butanol and acetic acid exerted different effects on the esterification reaction and the reaction was favoured by higher acetic acid concentration than butanol. Kinetics parameters, Km and Vmax values for both substrates and the specific activities of the three enzyme system were also determined. The beads morphology was examined using SEM. Batch-wise operational stability studies for both immobilized systems demonstrated that the immobilized lipase performed better in the batch wise reactor system than the continuous bioreactor system and that the immobilized lipase remained active for at least 5 cycles of batch wise esterification reactions. (author)

  3. Effektiv tillsyn av pågående verksamheter i Piteå kommun med MIFO fas 1 som verktyg : Underlag för strategival

    OpenAIRE

    Pettersson, Jakob

    2014-01-01

    The purpose of the study was to investigate how inventories of suspected polluted areas as a part of the planned control of existing companies cab be designed in order to achieve as great effect as possible. The study was conducted in cooperation with Piteå municipality. An analysis of regional inventory projects, local municipal strategies and a pilot study in Piteå was conducted. The experience from both the regional projects and the pilot study was that in order to achieve an effective con...

  4. Software supervisor: extension to the on-line codes utilization in order to help the process control

    International Nuclear Information System (INIS)

    Calculation is a complex problem, which is usually solved by human experts. The complexity and the potentiality of the software increases. The introduction of the calculations in real time systems needs additional specifications. These aims cab be achieved by means of the control of the knowledge based systems, as well as by the introduction of the software techniques in the existing computer world. The following examples are given: the automatic generation of the calculation methods (in control language) in the modular code systems; the calculations monitoring by the expert systems, in order to help the on-line operations

  5. Effects of Different Sweet Cherry Rootstocks and Drought Stress on

    OpenAIRE

    KÜÇÜKYUMUK, Zeliha

    2015-01-01

    Relation between drought stress, genotypic differences and nutrients are important in plant growth. The aim of the study was to determine the effects of different sweet cherry rootstocks grown in 50-liter pots and drought stress on nutrient (N, P, K, Ca, Mg, Zn, Mn, and Cu) concentrations of leaves. In this study 0900 Ziraat sweet cherry variety grafted on five different rootstocks (P. mahaleb, Mazzard, Gisela-6, MaxMa 14, CAB 6) were used. Four irrigation treatments (control or 100%, 75%, 50...

  6. Calumenin interacts with serum amyloid P component

    DEFF Research Database (Denmark)

    Vorum, H; Jacobsen, Christian; Honoré, Bent

    secretory pathway that include reticulocalbin, ERC-55, Cab45 and crocalbin. In order to further investigate the extracellular functions of calumenin we immobilized the recombinant protein to a column. After application of a placental tissue extract we were able to elute one protein that interacts with...... calumenin in the presence of Ca(2+). Amino acid sequencing identified this protein as serum amyloid P component (SAP). Furthermore, we verified and characterized the calumenin-SAP interaction by the surface plasmon resonance technique. The findings indicate that calumenin may participate in the...

  7. Uric acid is associated with features of insulin resistance syndrome in obese children at prepubertal stage

    OpenAIRE

    Gil-Campos, Mercedes; C.M Aguilera; Ca??ete, Ram??n; Gil Hern??ndez, ??ngel

    2009-01-01

    Los niveles elevados de ??cido ??rico plasm??ticos se asocian a la obesidad y pueden ser la expresi??n de un estado de resistencia insul??nica. El objetivo de este estudio ha sido evaluar la concentraci??n plasm??tica de ??cido ??rico en ni??os obesos y normales, exclusivamente en edad prepuberal, y determinar su relaci??n con las medidas antropom??tricas, la ingesta diet??tica y los par??metros asociados al s??ndrome de resistencia insul??nica. El estudio se llev?? a cab...

  8. Estudio sobre la adopción de variedades mejoradas de frijol en las principales zonas productoras de frijol de la Región Brunca de Costa Rica

    OpenAIRE

    Juan Carlos Hern\\u00E1ndez-Fonseca; Flor Ivette Elizondo-Porras

    2006-01-01

    En Costa Rica, en el periodo 2000- 2004 se liberaron tres variedades de frijol grano rojo: Bribri (2000), Cabécar (2003) y Telire (2004). El proceso de generación y difusión de estas variedades, se efectuó bajo la estrategia de Fitomejoramiento Participativo (FP). En el estudio se entrevistaron 201 productores de cuatro localidades y 16 caseríos de la Región Brunca. El estudio consideró los años 2002, 2003 y 2004. En el periodo agrícola 2004 el 70% del área de siembra ...

  9. El desarrollo del lenguaje en el segundo ciclo de educación infantil: propuesta didáctica

    OpenAIRE

    Cea Pérez de, María Elena

    2014-01-01

    El trabajo que se presenta a continuación se basa en la importancia que tiene el lenguaje, tanto oral como escrito, en el segundo ciclo de educación infantil, ya que a través de su utilización los niños serán capaces de expresar sus intereses, emociones, sentimientos, etc. y comunicarse con ellos mismos y con las personas de su entorno, para lograr integrarse en la sociedad en la que viven. Una vez expuesto el desarrollo del lenguaje, propongo una unidad didáctica que puede llevarse a cab...

  10. Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan

    OpenAIRE

    Martínez, Allyson K.; GORDON, EMILY; Sengupta, Arnab; Shirole, Nitin; Klepacki, Dorota; Martinez-Garriga, Blanca; Brown, Lewis M.; Benedik, Michael J.; Yanofsky, Charles; Mankin, Alexander S.; Vazquez-Laslop, Nora; Sachs, Matthew S.; Cruz-Vera, Luis R.

    2013-01-01

    A transcriptional attenuation mechanism regulates expression of the bacterial tnaCAB operon. This mechanism requires ribosomal arrest induced by the regulatory nascent TnaC peptide in response to free L-tryptophan (L-Trp). In this study we demonstrate, using genetic and biochemical analyses, that in Escherichia coli, TnaC residue I19 and 23S rRNA nucleotide A2058 are essential for the ribosome’s ability to sense free L-Trp. We show that the mutational change A2058U in 23S rRNA reduces the con...

  11. Preliminary design of the cold neutron source for the Centro Atomico Bariloche Electron LINAC Facility. I. Solid benzene as moderating material

    International Nuclear Information System (INIS)

    We present the results of preliminary calculations performed with the code MCNP-4C relative to the neutron field behavior within the moderator for the CAB-LINAC cold neutron source, using benzene at 89 K as moderating material. Throughout the design calculations nuclear data libraries previously generated and validated were used. The optimum dimensions for a slab and a grid moderator were calculated, with and without a pre moderator, from the point of view of neutron production and the time-width of the neutron pulse. (author)

  12. Placarding of road vehicles carrying radioactive materials

    International Nuclear Information System (INIS)

    The purpose of this Code is to give guidance on the placarding requirements for vehicles carrying radioactive materials by road in Great Britain and on the continent of Europe. Additional placards may be required regarding dangerous properties other than radioactivity. The labelling of packages for transport is dealt with in AECP 1030. This Code deals with two aspects of road vehicle placarding:-(a) placarding on the outside of road vehicles in Great Britain and on the continent of Europe, (b) a fireproof placard fixed in the driver's cab. Responsibility for placarding the vehicle rests with the carrier, but in practice the consignor may need to provide the placards. (U.K.)

  13. Reassessment of the economics of a coast advice system for go transit. CIGGT report No. 89-1

    Energy Technology Data Exchange (ETDEWEB)

    English, G.W.; Moynihan, T.W.; Boumeester, H.

    1989-01-01

    A team of Australian researchers developed a prototype train-borne computer system that provides visual advice to drivers on fuel efficient driving tactics. The system was tested in Australian service and demonstrated a mean fuel saving of 15% and greatly improved timekeeping. In February 1988, the system was tested on GO Transit revenue service trains in normal service on the Lakeshore route. A one-locomotive, four-coach consist with a cab control cubicle in the last coach was selected for the demonstration. This report describes the testing, the data collection, the model validation, fuel saving predictions, and economic benefits.

  14. LOSS OF HETEROZYGOSITY FOR MARKERS ON 22 CHROMOSOME IN SPORADIC SCHWANNOMA

    Institute of Scientific and Technical Information of China (English)

    卞留贯; 沈建康; 孙青芳; 邱永明; 徐纪文; 罗其中

    2000-01-01

    ffeSUnt6 Objectif Analyser la carte d' hetdrozgritd(LOH, lass of heterozgrity) pour marqueurs sur chromosome22 (CHR22 ) et son rapest avec scs manifeStations cliniques. afl~ In frdquence de LOH CHR22 a ate obServde chez 36sehwennomes per gel an poly-acrylamide denature et coloration an sel d' argent. L' indice de Proliferation de schndnnome etaitcolculd per immunohistochimie Ki-67, PCNA. haultats 15 SChwennomes (41. 6% ) out ~id une d' alldle. L' indian de ~if betion cab ieS fornd~ awe ~ etait significoti~t...

  15. Characterization of Summer Savory (Satureja hortensis L.) Honey by Physico-Chemical Parameters and Chromatographic / Spectroscopic Techniques (GC-FID/MS, HPLC-DAD, UV/VIS and FTIR-ATR)

    OpenAIRE

    Igor Jerković; Carlo Ignazio Giovanni Tuberoso; Goran Baranović; Zvonimir Marijanović; Marina Kranjac; Lidija Svečnjak; Piotr Marek Kuś

    2015-01-01

    Satureja hortensis L. unifloral honey was characterized by pollen analysis, electrical conductivity, pH and extensively by chromatographic and spectroscopic techniques. UV / VIS spectro-scopy measurements revealed total phenol content of 682.1 mg GAE / kg by Folin-Ciocalteu assay, antiox-idant capacity by DPPH assay of 1.7 mmol TEAC / kg and by FRAP assay of 4.3 mmol Fe2+ / kg as well as CIE L*a*b*Cab*h°ab chromaticity coordinates. GC-MS after headspace solid-phase microextraction (HS-SPME) r...

  16. Factores socioculturales que influyen en la práctica de la lactancia entre mujeres de baja renta en Fortaleza, Ceará, Brasil. Una perspectiva a partir del modelo del sol naciente de Leininger.

    OpenAIRE

    Henry, Beth A.; Nicolau, Ana I.O.; Américo, Camila F.; Ximenes, Lorena B.; Bernheim, Ruth G.; Oriá, Mónica OB.

    2010-01-01

    Esta investigación fue desarrollada para analizar los factores socioculturales que pueden influir en la práctica de la lactancia entre mujeres de baja renta en Fortaleza, Ceará, Brasil. Este estudio de observación utilizó la Teoría del Cuidado Cultural de Leininger para identificar y analizar los factores socioculturales clave. El estudio involucró a 12 gestantes y nodrizas. Usando un formulario de observación creado de acuerdo con el modelo del Sol Naciente (Leininger), fueron llevadas a cab...

  17. The GTC Public Archive

    Science.gov (United States)

    Alacid, J. Manuel; Solano, Enrique

    2015-12-01

    The Gran Telescopio Canarias (GTC) archive is operational since November 2011. The archive, maintained by the Data Archive Unit at CAB in the framework of the Spanish Virtual Observatory project, provides access to both raw and science ready data and has been designed in compliance with the standards defined by the International Virtual Observatory Alliance (IVOA) to guarantee a high level of data accessibility and handling. In this presentation I will describe the main capabilities the GTC archive offers to the community, in terms of functionalities and data collections, to carry out an efficient scientific exploitation of GTC data.

  18. NCBI nr-aa BLAST: CBRC-XTRO-01-2190 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-XTRO-01-2190 ref|NP_005468.1| hyperpolarization activated cyclic nucleotide-ga...ted potassium channel 4 [Homo sapiens] sp|Q9Y3Q4|HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyc...lic nucleotide-gated channel 4 emb|CAB42604.1| hyperpolarization-activated cyclic nucleotide gated cation ch...annel hHCN4 [Homo sapiens] gb|EAW77925.1| hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Homo sapiens] NP_005468.1 5e-71 75% ...

  19. Guaifenesin and increased sperm motility: a preliminary case report

    OpenAIRE

    Gary Means; Cristóbal S Berry-Cabán; Kurt Hammermeuller

    2010-01-01

    Gary Means1, Cristóbal S Berry-Cabán2, Kurt Hammermeuller11Department of Family Medicine, 2Department of Research, Womack Army Medical Center, Fort Bragg, NC, USABackground: A review of the literature and an extensive Medline search revealed that this is the first case report of the use of guaifenesin to increase sperm motility.Case: A 32-year-old male presented for an infertility evaluation. He reported an inability to conceive with his wife after 18 months of unprotect...

  20. A Theoretical Study of the Separation Principle in Size Exclusion Chromatography

    DEFF Research Database (Denmark)

    Wang, Yanwei; Teraoka, Iwao; Hansen, Flemming Yssing;

    2010-01-01

    The principle of polymer separation in size exclusion chromatography (SEC) is studied based on a classical equilibrium partitioning theory. The task is to examine the correlation between the mean span dimension of polymer chains and their equilibrium partition coefficients with confining pores....... Using an extended formulation of the recently developed confinement analysis from bulk structures (CABS) method, we calculate the partition coefficients for both linear and branched polymer chains with cylindrical pores—a model pore geometry that is considered to be more realistic for voids in SEC...

  1. Dynamic chemistry of disulfide terminated oligonucleotides in duplexes and double-crossover tiles

    DEFF Research Database (Denmark)

    Stefano, Mattia De; Gothelf, Kurt Vesterager

    2016-01-01

    Designed nanostructures formed by self-assembly of multiple DNA strands suffer from low stability at elevated temperature and under other denaturing conditions. Here, we propose a method to covalent coupling of all DNA strands in such structures by formation of disulfides, which also allows...... demonstrated. All the strands in the fully disulfide-linked structures are covalently and geometrically interlocked and it is demonstrated that the structures are stable towards heating and denaturants. Such a reversible system cab be exploited in applications where higher stability of DNA assemblies is needed...

  2. Diseño de sistema de control para coche inteligente

    OpenAIRE

    Belmonte Hernández, Pablo

    2009-01-01

    El presente proyecto es parte del Proyecto iCab que se está desarrollando en la Universidad Carlos III de Madrid. El objetivo es desarrollar vehículos autónomos que puedan desenvolverse por el Campus de Leganés sin necesitar ningún tipo de ayuda humana en la conducción. Se parte de un vehículo eléctrico comercial al que se le han realizado varias modificaciones para que pueda ser controlado por un PC, tanto la velocidad, como la aceleración, como el giro de las ruedas. La primera parte del pr...

  3. Top-down estimate of surface flux in the Los Angeles Basin using a mesoscale inverse modeling technique: assessing anthropogenic emissions of CO, NOx and CO2 and their impacts

    Directory of Open Access Journals (Sweden)

    S. C. Wofsy

    2012-12-01

    Full Text Available We present top-down estimates of anthropogenic CO, NOx and CO2 surface fluxes at mesoscale using a Lagrangian model in combination with three different WRF model configurations, driven by data from aircraft flights during the CALNEX campaign in southern California in May–June 2010. The US EPA National Emission Inventory 2005 (NEI 2005 was the prior in the CO and NOx inversion calculations. The flux ratio inversion method, based on linear relationships between chemical species, was used to calculate the CO2 inventory without prior knowledge of CO2 surface fluxes. The inversion was applied to each flight to estimate the variability of single-flight-based flux estimates. In Los Angeles (LA County, the uncertainties on CO and NOx fluxes were 10% and 15%, respectively. Compared with NEI 2005, the CO posterior emissions were lower by 43% ± 6% in LA County and by 37% ± 10% in the South Coast Air Basin (SoCAB. NOx posterior emissions were lower by 32% ± 10% in LA County and by 27% ± 15% in the SoCAB. NOx posterior emissions were 40% lower on weekends relative to weekdays. The CO2 posterior estimates were 183 ± 18 Tg yr−1 in SoCAB. A flight during ITCT in 2002 was used to estimate emissions in the LA Basin in 2002. From 2002 to 2010, the CO and NOx posterior emissions decreased by 41% and 37%, respectively, in agreement with previous studies. Over the same time period, CO2 emissions increased by 10% ± 14% in LA County but decreased by 4% ± 10% in the SoCAB, a statistically insignificant change. Overall, the posterior estimates were in good agreement with the California Air Resources Board (CARB inventory, with differences of 15% or less. However, the posterior spatial distribution in the basin was significantly different from CARB for NOx emissions. WRF-Chem mesoscale chemical-transport model simulations allowed an evaluation of differences in chemistry using different inventory assumptions, including NEI 2005, CARB 2010 and the posterior

  4. Top-down estimate of surface flux in the Los Angeles Basin using a mesoscale inverse modeling technique: assessing anthropogenic emissions of CO, NOx and CO2 and their impacts

    Directory of Open Access Journals (Sweden)

    J. Brioude

    2013-04-01

    Full Text Available We present top-down estimates of anthropogenic CO, NOx and CO2 surface fluxes at mesoscale using a Lagrangian model in combination with three different WRF model configurations, driven by data from aircraft flights during the CALNEX campaign in southern California in May–June 2010. The US EPA National Emission Inventory 2005 (NEI 2005 was the prior in the CO and NOx inversion calculations. The flux ratio inversion method, based on linear relationships between chemical species, was used to calculate the CO2 inventory without prior knowledge of CO2 surface fluxes. The inversion was applied to each flight to estimate the variability of single-flight-based flux estimates. In Los Angeles (LA County, the uncertainties on CO and NOx fluxes were 10% and 15%, respectively. Compared with NEI 2005, the CO posterior emissions were lower by 43% in LA County and by 37% in the South Coast Air Basin (SoCAB. NOx posterior emissions were lower by 32% in LA County and by 27% in the SoCAB. NOx posterior emissions were 40% lower on weekends relative to weekdays. The CO2 posterior estimates were 183 Tg yr−1 in SoCAB. A flight during ITCT (Intercontinental Transport and Chemical Transformation in 2002 was used to estimate emissions in the LA Basin in 2002. From 2002 to 2010, the CO and NOx posterior emissions decreased by 41% and 37%, respectively, in agreement with previous studies. Over the same time period, CO2 emissions increased by 10% in LA County but decreased by 4% in the SoCAB, a statistically insignificant change. Overall, the posterior estimates were in good agreement with the California Air Resources Board (CARB inventory, with differences of 15% or less. However, the posterior spatial distribution in the basin was significantly different from CARB for NOx emissions. WRF-Chem mesoscale chemical-transport model simulations allowed an evaluation of differences in chemistry using different inventory assumptions, including NEI 2005, a gridded CARB

  5. AcEST: DK961774 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 8. 5' end sequence. DK961774 CL1Contig7 Show DK961774 Clone id TST39A01NGRL0011_B08 Library TST39 Length 673... Definition Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0011_B08. 5' end sequence. Accession DK961774...generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK96177...Oryza sativa subsp. japonica GN=CAB1R PE=2 SV=2 Length = 265 Score = 319 bits (818), Expect = 7e-87 Identities = 152/177... (85%), Positives = 162/177 (91%), Gaps = 4/177 (2%) Frame = +3 Query

  6. Comparative Analysis of the Conventional and Novel pmo (Particulate Methane Monooxygenase) Operons from Methylocystis Strain SC2

    OpenAIRE

    Ricke, Peter; Erkel, Christoph; Kube, Michael; Reinhardt, Richard; Liesack, Werner

    2004-01-01

    In addition to the conventional pmoA gene (pmoA1) encoding the active site polypeptide of particulate methane monooxygenase, a novel pmoA gene copy (pmoA2) is widely distributed among type II methanotrophs (methane-oxidizing bacteria [MOB]) (M. Tchawa Yimga, P. F. Dunfield, P. Ricke, J. Heyer, and W. Liesack, Appl. Environ. Microbiol. 69:5593-5602, 2003). Here we report that the pmoA1 and pmoA2 gene copies in the type II MOB Methylocystis strain SC2 are each part of a complete pmoCAB gene clu...

  7. El arbitraje en materia de propiedad intelectual

    OpenAIRE

    Montesinos García, Ana

    2013-01-01

    En el presente artículo se analiza la conveniencia del arbitraje como fórmula alternativa de solución de controversias en el ámbito de la propiedad intelectual. Se estudia tanto el arbitraje general conforme a la Ley 60/2003, de Arbitraje, como el arbitraje especial de la Comisión de la Propiedad Intelectual previsto en el artículo 158 del Texto Refundido de la Ley de Propiedad Intelectual y regulado en el RD 1889/2011, de 30 de diciembre. Se concluye con las últimas tendencias llevadas a cab...

  8. A statistical mixture method to reveal bottom-up and top-down factors guiding the eye-movements

    OpenAIRE

    Couronné, Thomas; Guérin-Dugué, Anne; Michel DUBOIS; Faye, Pauline; MARENDAZ, Christian

    2010-01-01

    When people gaze at real scenes, their visual attention is driven both by a set of bottom-up processes coming from the signal properties of the scene and also from top-down effects such as the task, the affective state, prior knowledge, or the semantic context. The context of this study is an assessment of manufactured objects (here car cab interior). From this dedicated context, this work describes a set of methods to analyze the eye-movements during the visual scene evaluation. But these me...

  9. Can LTE become an alternative to GSM-R?

    DEFF Research Database (Denmark)

    Sniady, Aleksander; Soler, José

    the European Train Control System (ETCS) messages and voice communication for railways. ETCS system offers safe and reliable in-cab signaling and train supervision, which reduces the risk of train driver error and increases the track occupancy. Thus, GSM-R, as a basis for ETCS, contributes to the......GSM-R is the first widely adopted international mobile communication network for railways. It is a part of the European Rail Traffic Management System (ERTMS), which substitutes legacy national railway signaling technologies. GSM-R is designed to provide two fundamental services: transmission of...

  10. An overview of GSM-R technology and its shortcomings

    DEFF Research Database (Denmark)

    Sniady, Aleksander; Soler, José

    2012-01-01

    Railway communication technologies undergo a revolutionary change bringing them from the analog to the digital era. The European Rail Traffic Management System (ERTMS) replaces numerous incompatible analog radio systems, classical side-track signs and legacy in-cab signaling with an integrated...... comprehensive solution. This paper presents an overview of GSM-Railways (GSM-R), which is the unified communication technology supporting ERTMS. Its shortcoming in terms of capacity and capability are discussed as a foundation for the need for further developments....

  11. Efeito da massa molar do acetobutirato de celulose e da adição de poli(3-hidroxibutirato sobre as características das microesferas e o prolongamento da liberação do cetoprofeno

    Directory of Open Access Journals (Sweden)

    BRUNA SILVA de OLIVEIRA

    2011-06-01

    Full Text Available No presente trabalho, foram elaboradas microesferas de acetobutirato de celulose (ABC contendo cetoprofeno com o objetivo de prolongar a liberação do fármaco. Utilizou-se a técnica de emulsão e evaporação do solvente, variando-se os seguintes parâmetros: massa molar do ABC e a adição ou não de poli(3-hidroxibutirato (PHB, segundo um planejamento fatorial 22. Maiores eficiências de encapsulação do cetoprofeno foram obtidas quando utilizado ABC com maior massa molar e a adição do PHB levou a uma diminuição do percentual de fármaco encapsulado. Todas as formulações originaram partículas esféricas, com cristais de fármacos aderidos à superfície externa e matriz polimérica porosa quando adicionado o PHB. Os perfis de liberação in vitro indicaram que o aumento da massa molar do ABC levou a uma diminuição do percentual de fármaco inicialmente liberado e a um prolongamento de sua liberação. Por outro lado, a adição do PHB acelerou a liberação do cetoprofeno a partir das microesferas. Palavras-chave: Microesferas. Cetoprofeno. Preparações de liberação retardada. ABSTRACT Effects of cellulose acetate butyrate molar weight and addition of poly(3-hydroxybutyrate on microsphere morphology and ketoprofen prolonged release In the present study, cellulose acetate butyrate (CAB microspheres containing ketoprofen were produced, with the objective of prolonging its release. The emulsion/solvent evaporation technique was used to make the spheres, varying the parameters (1 CAB molecular weight and (2 addition or not of poly(3-hydroxybutyrate [PHB], to optimize drug encapsulation, following a 2² factorial design. Higher ketoprofen encapsulation efficiency was obtained when higher molecular weight CAB was used, while the addition of PHB caused a decrease in the percentage of encapsulated drug. All the preparations produced spherical particles, with drug crystals adhering to the external surface, and a porous polymer matrix

  12. Mélanges de polymères thermoplastiques à matrice biosourcée : amélioration de la résistance au choc d'un dérivé cellulosique

    OpenAIRE

    Besson, François

    2013-01-01

    This work has been funded by the Industrial Chair in Biopalstics, financed by MINES ParisTech and fives industrial partners: Arkema, L'Oréal, Nestlé, PSA Peugeot-Citroën and Schneider Electric, whose objective is to develop new durable biobased materials. The aim of this thesis is to find new properties for an old-fashioned biobased plastic - cellulose esters - by blending with polyolefins. We started the project with a screening of the cellulose ester (cellulose acetate butyrate or CAB) prop...

  13. Micro scale distribution of nanoparticles studied with X-ray near-field scattering

    International Nuclear Information System (INIS)

    In the present study, we investigate the micron-scale inhomogeneous distribution of silica nanoparticles with X-ray near-field scattering. This technique allows us to measure structures of soft matters on a large size scale that is complementary to conventional ultra-small-angle X-ray scattering and/or X-ray imaging. We applied the technique to the observation of the anisotropic structural distribution of silica aggregates in uniaxially stretched rubber. The scattering images show anisotropic butterfly patterns that correspond to the inhomogeneous density distribution of silica aggregates. The spatial distribution of the inhomogeneity in the stretched rubber cab also be determined by this technique. (author)

  14. Podnikatelský plán

    OpenAIRE

    Neuvirt, Jakub

    2014-01-01

    The diploma thesis consist of the theoretical and the practical part. In the theoretical part concepts regarding to business activities are explained. Also you can find there detailed explaining of the structure of the business plan. The aim of the theoretical part is to provide instructions for making a business plan. The Practical part is focused on the business plan of founding the cab service in Chotěboř. It contains an analysis of this plan. The aim is to found out, if the business plan ...

  15. Remobilization of leaf S compounds and senescence in response to restricted sulphate supply during the vegetative stage of oilseed rape are affected by mineral N availability

    OpenAIRE

    Dubousset, L.; Abdallah, M.; Desfeux, A. S.; Etienne, P.; MEURIOT, F.; Hawkesford, M. J.; Gombert, J.; Ségura, R.; Bataillé, M-P.; Rezé, S.; Bonnefoy, J.; Ameline, A. F.; OURRY, A.; Dily, F. Le; Avice, J. C.

    2009-01-01

    The impact of sulphur limitation on the remobilization of endogenous S compounds during the rosette stage of oilseed rape, and the interactions with N availability on these processes, were examined using a long-term 34SO4 2− labelling method combined with a study of leaf senescence progression (using SAG12/Cab as a molecular indicator) and gene expression of the transporters, BnSultr4;1 and BnSultr4;2, involved in vacuolar sulphate efflux. After 51 d on hydroponic culture at 0.3 mM 34SO4 2− (...

  16. The risk of injury to children in compact pickup trucks.

    Science.gov (United States)

    Winston, Flaura K; Durbin, Dennis

    2002-01-01

    Nearly one million compact pickup trucks were sold last year in the US. Manufacturers now produce extended-cab models of pickups such as the Ford Ranger, Chevrolet S-10, Dodge Dakota, and Toyota Tacoma that can accommodate at least two rear-seated passengers, making them attractive to families with children. However, the safety of these rear seats for children has not been determined. This Issue Brief summarizes a new study that examines and quantifies the risk of injury to children riding in compact pickup trucks. Based on these findings, parents should be advised against using these vehicles as family transportation. PMID:12528740

  17. Gene : CBRC-HSAP-06-0074 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-HSAP-06-0074 6 A Cannabinoids receptors CB1b CNR1_PANTR 0.0 100% ref|NP_057167.2| central c ... o sapiens] emb|CAB96726.1| cannabinoid receptor 1 (brain ) [Homo sapiens] gb|AAO67710.1| cannabinoid recepto ... mo sapiens] gb|AAI00970.1| Cannabinoid receptor 1 (brain ) [Homo sapiens] gb|AAI00971.1| Cannabinoid recepto ... r 1 (brain ) [Homo sapiens] gb|AAI00969.1| Cannabinoid recepto ... r 1 (brain ) [Homo sapiens] gb|EAW48574.1| cannabinoid recepto ...

  18. Adaptación de modelos de datos tácticos de sistemas de información para mando y control a la gestión de emergencias

    OpenAIRE

    Carvajal Rodrigo, Federico Jesús

    2008-01-01

    Con la presente Tesis doctoral se pretende profundizar en la problemática del modelado de datos en el ámbito militar, analizar las diferentes soluciones de interoperabilidad entre sistemas C2IS que están vigentes hoy en día y las que están en fase de experimentación en la actualidad, para adaptarlas al entorno de la gestión y coordinación de crisis civiles en las que participan distintos cuerpos de seguridad y servicios de emergencia. Para conseguir este objetivo global se ha llevado a cab...

  19. Improving room acoustics at low frequencies with multiple loudspeakers and time based room correction

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2008-01-01

    Small and medium size rectangular rooms are often used for sound reproduction. These rooms have substantial acoustical problems at low frequencies primarily caused by the reflections from the room boundaries. The spatial variation in sound pressure level (SPL) can be up to 30 dB in a room at low...... wall. With the back wall reflection removed a homogeneous sound field will be created in the whole room at low frequencies. Simulations and measurements of normal size listening rooms show that 4 loudspeakers are enough to even the sound field in a room. The CABS system is controlled by a developed DSP...

  20. Eficacia de la terapia cognitivo conductual (TCC) y de la TCC-focalizada en el trauma en infancia maltratada

    OpenAIRE

    Prieto Larrocha, Macarena

    2016-01-01

    Objetivo: El propósito fundamental del presente trabajo fue proporcionar evidencia empírica acerca de la eficacia del modelo de Terapia Cognitivo Conductual (TCC) en general, y del modelo de TCC-Focalizada en el Trauma (TCC-FT) en particular, para el tratamiento del estrés postraumático, la sintomatología depresiva y los problemas del comportamiento, en niños y adolescentes víctimas de maltrato intrafamiliar crónico en situación de acogimiento residencial o familiar. Para ello, se llevó a cab...