WorldWideScience

Sample records for Pythagorean theorem geometric transformation Euclidean geometry MSC 2000 51M04, 51M05, 51N20

  1. Experimental Conditions: SE51_S01_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available SE51_S01_M01_D01 SE51 RIKEN tandem mass spectral database (ReSpect) for phytochemic...als: A plant-specific MS/MS-based data resource and database SE51_S01 L. japonicus accessions SE51_S01_M01 N

  2. The cross section measurements for the 51V(n, α)48Sc and 51V(n,p)51Ti reactions

    International Nuclear Information System (INIS)

    Hu Shangbin; Kong Xiangzhong; Yang Jingkang

    1999-01-01

    The cross sections for 51 V(n, α) 48 Sc and 51 V(n,p) 51 Ti have been measured by using the activation method relative to the cross sections of 27 Al(n, α) 24 Na in the neutron energy range 13.4 --14.8 MeV. The results are compared with the published data. The neutron energies were determined by the method of cross section ratios for the reactions 90 Zr(n.2n) 89 Zr by 93 Nb(n,2n) 92m Nb

  3. Far infrared polarimetry of W51A and M42

    Energy Technology Data Exchange (ETDEWEB)

    Cudlip, W; Furniss, I; King, K J; Jennings, R E [University Coll., London (UK). Dept. of Physics and Astronomy

    1982-09-01

    A far infrared polarimeter has been designed for use with a balloon-borne telescope. It uses a rapidly rotating wire grid polarizer with the chopping secondary mirror of the telescope synchronized to the rate of rotation. Observations of M42 using this system show a far infrared polarization of 2.2 +- 0.4 per cent, nearly orthogonal to the near infrared polarization which is usually attributed to dust absorption. Observations of W51A show a much smaller value of the polarization of 0.8 +- 0.5 per cent.

  4. The Population of Supernova Remnants in M51

    Science.gov (United States)

    Long, Knox S.; Blair, William P.; Kuntz, K. D.; Winkler, P. Frank

    2017-08-01

    The nearby, actively star-forming, nearly face-on spiral galaxy, M51 (NGC 5194/5), has been the site of four supernovae since 1941. As a result it should have a rich population of young supernova remnants (SNRs). Here we describe a search for optical SNRs in M51 among the 298 X-ray sources discovered inside the D25 contour in deep Chandra observations. The search uses interference filter images obtained with the WFC3 on Hubble Space Telescope and more recent images from GMOS on Gemini North. Of 80 emission nebulae identified in the HST images as SNR candidates based on elevated [SII]: Ha ratios compared to HII regions, 40 have X-ray counterparts. The diameters of the SNRs and SNR candidates detected with HST are systematically smaller than seen in SNR populations of other galaxies at comparable distances. However, this is most likely an instrumental effect, which our ongoing analysis of the new GMOS images will correct. At that point, we will be able to make of fair multi-wavelength comparison of the SNR population in M51 with other nearby, actively star-forming spiral galaxies, such as M83 and NGC6946.

  5. Discovery of two eclipsing X-ray binaries in M 51

    Science.gov (United States)

    Wang, Song; Soria, Roberto; Urquhart, Ryan; Liu, Jifeng

    2018-04-01

    We discovered eclipses and dips in two luminous (and highly variable) X-ray sources in M 51. One (CXOM51 J132943.3+471135) is an ultraluminous supersoft source, with a thermal spectrum at a temperature of about 0.1 keV and characteristic blackbody radius of about 104 km. The other (CXOM51 J132946.1+471042) has a two-component spectrum with additional thermal-plasma emission; it approached an X-ray luminosity of 1039erg s-1 during outbursts in 2005 and 2012. From the timing of three eclipses in a series of Chandra observations, we determine the binary period (52.75 ± 0.63 hr) and eclipse fraction (22% ± 0.1%) of CXOM51 J132946.1+471042. We also identify a blue optical counterpart in archival Hubble Space Telescope images, consistent with a massive donor star (mass of ˜20-35M⊙). By combining the X-ray lightcurve parameters with the optical constraints on the donor star, we show that the mass ratio in the system must be M_2/M_1 ≳ 18, and therefore the compact object is most likely a neutron star (exceeding its Eddington limit in outburst). The general significance of our result is that we illustrate one method (applicable to high-inclination sources) of identifying luminous neutron star X-ray binaries, in the absence of X-ray pulsations or phase-resolved optical spectroscopy. Finally, we discuss the different X-ray spectral appearance expected from super-Eddington neutron stars and black holes at high viewing angles.

  6. DEEP IMAGING OF M51: A NEW VIEW OF THE WHIRLPOOL’S EXTENDED TIDAL DEBRIS

    International Nuclear Information System (INIS)

    Watkins, Aaron E.; Mihos, J. Christopher; Harding, Paul

    2015-01-01

    We present deep, wide-field imaging of the M51 system using CWRU’s Burrell Schmidt Telescope at KPNO to study the faint tidal features that constrain its interaction history. Our images trace M51's tidal morphology down to a limiting surface brightness of μ B,lim ∼ 30 mag arcsec −2 and provide accurate colors (σ B−V <0.1) down to μ B ∼ 28. We identify two new tidal streams in the system (the south and northeast plumes) with surface brightnesses of μ B = 29 and luminosities of ∼10 6 L ⊙,B . While the northeast plume may be a faint outer extension of the tidal “crown” north of NGC 5195 (M51b), the south plume has no analog in any existing M51 simulation and may represent a distinct tidal stream or disrupted dwarf galaxy. We also trace the extremely diffuse northwest plume out to a total extent of 20′ (43 kpc) from NGC 5194 (M51a) and show it to be physically distinct from the overlapping bright tidal streams from M51b. The northwest plume’s morphology and red color (B−V=0.8) instead argue that it originated from tidal stripping of M51a’s extreme outer disk. Finally, we confirm the strong segregation of gas and stars in the southeast tail and do not detect any diffuse stellar component in the H i portion of the tail. Extant simulations of M51 have difficulty matching both the wealth of tidal structure in the system and the lack of stars in the H i tail, motivating new modeling campaigns to study the dynamical evolution of this classic interacting system

  7. 20 CFR 901.51 - Decision of the Joint Board.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Decision of the Joint Board. 901.51 Section 901.51 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE... final decision. In making its decision the Joint Board will review the record of such portions thereof...

  8. Study of the V{sup 51} (p,n)Cr{sup 51} reaction and the energy levels in Cr{sup 51}; Etude de la reaction {sup 51}V (p,n){sup 51}Cr et contribution a la spectroscopie de {sup 51}Cr

    Energy Technology Data Exchange (ETDEWEB)

    Cassacnou, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-07-01

    Neutrons and gamma rays from the reaction {sup 51}V(p,n){sup 51}Cr have been studied between 2.3 and 5.1 MeV Energy levels of {sup 51}Cr at 0.75, 1.15, 1.35, 1.47 and 1.56 MeV and unresolved levels at 1.94, 2.4, 2.75 and 2.9 MeV are observed. The gamma ray cascades of the low-lying states of {sup 51}Cr up to 2.5 MeV excitation energy have been completely determined through coincidence measurements. From the cascade ratios and gamma ray yields, excitation functions for the {sup 51}V(p,n){sup 51}Cr reactions, leading to the five lowest levels of {sup 51}Cr have been obtained from reaction threshold to 4.6 MeV. The analysis of cross section fluctuations with good resolution shows they are due to the excitation of unresolved compound nucleus isolated resonances. From the decay scheme and an Hauser-Feshbach calculation of the {sup 51}V(p,n) excitation functions, spin assignments of 3/2{sup -}, or 5/2{sup -} (0.75 MeV), 7/2{sup -} (1.15 MeV), 3/2{sup -} (1.35 MeV), 5/2{sup -} (1.47 MeV) are proposed. (author) [French] La reaction {sup 51}V(p,n){sup 51}Cr a ete etudiee entre 2,3 et 5,1 MeV en detectant les neutrons et le rayonnement gamma de desexcitation des niveaux de {sup 51}Cr a 0,75, 1,15, 1,35, 1,47 et 1,56 MeV et de groupes non resolus de niveaux a 1,94, 2,4, 2,75 et 2,9 MeV. Des mesures de coincidence ont permis de determiner completement les desexcitations en cascade dans {sup 51}Cr jusqu'a 2,5 MeV et d'etablir, a partir des mesures de rayonnement gamma, les fonctions d'excitation des reactions {sup 51}V(p,n){sup 51}Cr formant les cinq premiers niveaux de {sup 51}Cr depuis le seuil jusqu'a 4,6 MeV. L'analyse en bonne resolution des fluctuations observees sur les sections efficaces montrent qu'elles sont dues a des resonances isolees du noyau compose non resolubles dans cette experience. Le schema de desexcitation de {sup 51}Cr et un calcul Hauser-Feshbach des fonctions d'excitation conduisent a proposer les spins suivants: 3/2{sup -} ou 5/2{sup -} pour le niveau

  9. DENSITY WAVE KINEMATICS AND GIANT MOLECULAR ASSOCIATION FORMATION IN M51

    NARCIS (Netherlands)

    RAND, RJ

    1993-01-01

    New spectroscopic observations of the ionized gas (Halpha and [N II] lines) in M51 are combined with existing CO, H I, and Halpha data to look for kinematic evidence that the gas is responding to a spiral density wave. Possible mechanisms for the formation of the approximately 3 x 10(7) M. giant

  10. 20 CFR 222.51 - When a natural child is dependent.

    Science.gov (United States)

    2010-04-01

    ... FAMILY RELATIONSHIPS Child Support and Dependency § 222.51 When a natural child is dependent. The... employee's earnings record and the relationship of the child to the employee, the child will be considered... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When a natural child is dependent. 222.51...

  11. Photometric study of the M51 system

    International Nuclear Information System (INIS)

    Burkhead, M.S.

    1978-01-01

    Photoelectric and photographic data are presented for the two components of the M51 system, NGC 5194 and NGC 5195. The photoelectric observations (UBV and I) are presented as a series of drift scans with various diaphragm sizes covering the bright central and faint outer regions. These data indicate the complexity and the very large extent of the system. Colors and magnitudes of the spiral arms are presented. The I data in particular show the broad spiral features first shown photographically by Zwicky. Deep, integrated photographic plates (IIIa-J) also show the large, structured outer regions and the complex nature of the region between the two galaxies. Calibrated contour maps and integrated luminosities of the system are presented.The maximum detected extent of the system is 40 arcmin or 120kpc. If a M/L ratio of 10 is assumed, the mass in the outer envelope is equal to the mass obtained for the more familiar bright optical components.These data and their presentation in the form of photoelectric drift scans, composite photographs, contour maps, and three-dimensional plots show the marvelous complexity of the system. It would seem that the individual galaxies, NGC 5194 and NGC 5195, cannot be considered separately but must be studied in the context of their being members of the M51 system

  12. Amorphous-to-Cu51Zr14 phase transformation in Cu60Ti20Zr20 alloy

    International Nuclear Information System (INIS)

    Cao, Q P; Zhou, Y H; Horsewell, A; Jiang, J Z

    2003-01-01

    The kinetics of an amorphous-to-Cu 51 Zr 14 phase transformation in an as-cast Cu 60 Ti 20 Zr 20 rod have been investigated by differential scanning calorimetry. The relative volume fractions of the transferred crystalline phase as a function of annealing time, obtained at 713, 716, 723, 728, and 733 K, have been analysed in detail using 14 nucleation and growth models together with the JMA model. A time-dependent nucleation process is revealed. A steady-state nucleation rate of the order of 10 22 - 10 23 nuclei m -3 s -1 in the temperature range 713-733 K and an activation energy of the order of 550 kJmol -1 for the phase transformation in the as-cast Cu 60 Ti 20 Zr 20 rod were detected, for which some possible reasons are suggested

  13. EnviroAtlas - Cleveland, OH - 51m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. In this community, vegetated cover is defined as Trees & Forest,...

  14. Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.

    Science.gov (United States)

    Warrilow, Andrew G; Parker, Josie E; Kelly, Diane E; Kelly, Steven L

    2013-03-01

    Candida albicans CYP51 (CaCYP51) (Erg11), full-length Homo sapiens CYP51 (HsCYP51), and truncated Δ60HsCYP51 were expressed in Escherichia coli and purified to homogeneity. CaCYP51 and both HsCYP51 enzymes bound lanosterol (K(s), 14 to 18 μM) and catalyzed the 14α-demethylation of lanosterol using Homo sapiens cytochrome P450 reductase and NADPH as redox partners. Both HsCYP51 enzymes bound clotrimazole, itraconazole, and ketoconazole tightly (dissociation constants [K(d)s], 42 to 131 nM) but bound fluconazole (K(d), ~30,500 nM) and voriconazole (K(d), ~2,300 nM) weakly, whereas CaCYP51 bound all five medical azole drugs tightly (K(d)s, 10 to 56 nM). Selectivity for CaCYP51 over HsCYP51 ranged from 2-fold (clotrimazole) to 540-fold (fluconazole) among the medical azoles. In contrast, selectivity for CaCYP51 over Δ60HsCYP51 with agricultural azoles ranged from 3-fold (tebuconazole) to 9-fold (propiconazole). Prothioconazole bound extremely weakly to CaCYP51 and Δ60HsCYP51, producing atypical type I UV-visible difference spectra (K(d)s, 6,100 and 910 nM, respectively), indicating that binding was not accomplished through direct coordination with the heme ferric ion. Prothioconazole-desthio (the intracellular derivative of prothioconazole) bound tightly to both CaCYP51 and Δ60HsCYP51 (K(d), ~40 nM). These differences in binding affinities were reflected in the observed 50% inhibitory concentration (IC(50)) values, which were 9- to 2,000-fold higher for Δ60HsCYP51 than for CaCYP51, with the exception of tebuconazole, which strongly inhibited both CYP51 enzymes. In contrast, prothioconazole weakly inhibited CaCYP51 (IC(50), ~150 μM) and did not significantly inhibit Δ60HsCYP51.

  15. EnviroAtlas - Durham, NC - 51m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the...

  16. EnviroAtlas - Portland, ME - 51m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the...

  17. EnviroAtlas - Fresno, CA - 51m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the...

  18. EnviroAtlas - Phoenix, AZ - 51m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the...

  19. EnviroAtlas - Durham, NC - 51m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the...

  20. Classical geometry Euclidean, transformational, inversive, and projective

    CERN Document Server

    Leonard, I E; Liu, A C F; Tokarsky, G W

    2014-01-01

    Features the classical themes of geometry with plentiful applications in mathematics, education, engineering, and science Accessible and reader-friendly, Classical Geometry: Euclidean, Transformational, Inversive, and Projective introduces readers to a valuable discipline that is crucial to understanding bothspatial relationships and logical reasoning. Focusing on the development of geometric intuitionwhile avoiding the axiomatic method, a problem solving approach is encouraged throughout. The book is strategically divided into three sections: Part One focuses on Euclidean geometry, which p

  1. THE DISTANCE TO M51

    Energy Technology Data Exchange (ETDEWEB)

    McQuinn, Kristen B. W. [University of Texas at Austin, McDonald Observatory, 2515 Speedway, Stop C1400 Austin, TX 78712 (United States); Skillman, Evan D. [Minnesota Institute for Astrophysics, School of Physics and Astronomy, 116 Church Street, S.E., University of Minnesota, Minneapolis, MN 55455 (United States); Dolphin, Andrew E. [Raytheon Company, 1151 E. Hermans Road, Tucson, AZ 85756 (United States); Berg, Danielle [Center for Gravitation, Cosmology and Astrophysics, Department of Physics, University of Wisconsin Milwaukee, 1900 East Kenwood Boulevard, Milwaukee, WI 53211 (United States); Kennicutt, Robert, E-mail: kmcquinn@astro.as.utexas.edu [Institute for Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom)

    2016-07-20

    Great investments of observing time have been dedicated to the study of nearby spiral galaxies with diverse goals ranging from understanding the star formation process to characterizing their dark matter distributions. Accurate distances are fundamental to interpreting observations of these galaxies, yet many of the best studied nearby galaxies have distances based on methods with relatively large uncertainties. We have started a program to derive accurate distances to these galaxies. Here we measure the distance to M51—the Whirlpool galaxy—from newly obtained Hubble Space Telescope optical imaging using the tip of the red giant branch method. We measure the distance modulus to be 8.58 ± 0.10 Mpc (statistical), corresponding to a distance modulus of 29.67 ± 0.02 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian Maximum Likelihood technique that reduces measurement uncertainties.

  2. EnviroAtlas - New York, NY - 51m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. In this community, forest is defined as Trees & Forest. There is a...

  3. Glomerular filtration rate by {sup 51}chomium and {sup 113m}indium labeled EDTA in horses; Taxa de filtracao glomerular pelo EDTA marcado com {sup 51}cromo e com {sup 113m}indio em equinos

    Energy Technology Data Exchange (ETDEWEB)

    Maliska, C.; D' Almeida, J.; Pellegrini, P.M.; Schimit, T.S. [Hospital Central do Exercito (HCE), Rio de Janeiro, RJ (Brazil). Servico de Medicina Nuclear; Pinho, W.R. [Centro de Ensino Superior, Valenca, RJ (Brazil). Fac. de Medicina Veterinaria; Lima, J.E.T. [Instituto Nacional do Cancer (INCa), Rio de Janeiro, RJ (Brazil). Servico de Medicina Nuclear

    2009-07-01

    The glomerular filtration rate was determined in nine healthy horses, six male and three female, aged two to 12-year-old, by means of {sup 51}Cr and {sup 113m}In labeled EDTA single injection technique. The glomerular filtration rate was calculated from the plasma disappearance curve and the volume of distribution of the radiotracer, {sup 51}Cr-EDTA or {sup 113m}In-EDTA. The result (mean +- standard deviation) was 148.80 +- 26.42 m L.min{sup -1}.100 kg. It is concluded that the measurement of glomerular filtration rate by {sup 51}Cr-EDTA or {sup 113m}In-EDTA by single injection technique eliminates the bladder catheterization, and for its simplicity, convenience, accuracy, and low dose of radiation, can be used in horses as a method of choice in clinical routine. (author)

  4. Spacetime and Euclidean geometry

    Science.gov (United States)

    Brill, Dieter; Jacobson, Ted

    2006-04-01

    Using only the principle of relativity and Euclidean geometry we show in this pedagogical article that the square of proper time or length in a two-dimensional spacetime diagram is proportional to the Euclidean area of the corresponding causal domain. We use this relation to derive the Minkowski line element by two geometric proofs of the spacetime Pythagoras theorem.

  5. 22 CFR 51.26 - Photographs.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Photographs. 51.26 Section 51.26 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.26 Photographs. The applicant must submit with his or her application photographs as prescribed by the Department that are a...

  6. EnviroAtlas - Minneapolis/St. Paul, MN - 51m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. In this community, forest is defined as Trees and Forest and Woody...

  7. 27 CFR 5.1 - General.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false General. 5.1 Section 5.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF DISTILLED SPIRITS Scope § 5.1 General. The regulations in this...

  8. 22 CFR 5.1 - Introduction.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Introduction. 5.1 Section 5.1 Foreign Relations DEPARTMENT OF STATE GENERAL ORGANIZATION § 5.1 Introduction. The sections in this part 5 are issued pursuant to section 3 of the Administrative Procedure Act, 5 U.S.C. 552, effective July 4, 1967. ...

  9. 24 CFR 51.105 - Exceptions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Exceptions. 51.105 Section 51.105... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for non... acceptability standard of 65 decibels, the Acceptable Zone may be shifted to Ldn 70 on a case-by-case basis if...

  10. Biliary excretion and distribution of 51Cr(III) and 51Cr(VI) in rats

    International Nuclear Information System (INIS)

    Cikrt, M.; Bencko, V.

    1979-01-01

    The biliary excretion and distribution of 51 Cr after intravenous administration of 51 Cr(III) ( 51 CrCl 3 ) or 51 Cr(VI) (Na 2 51 CrO 4 .4H 2 O) were studied in rats. The cumulative biliary excretion of 51 Cr 24 hrs after the injection was significantly higher after administration of 51 Cr(VI) than of 51 Cr(III) (3.51+-0.7% and 0.51+-0.05% of administered dose, respectively). This difference was especially due to a higher rate of biliary excretion of 51 Cr in the first hours after 51 Cr(VI) administration. The excretion of 51 Cr via feces was also higher after administration of 51 Cr(VI) (7.35+-0.45%) of administered dose, as against 4.23+-0.23% after 51 Cr(III). On the other hand, no significant difference in urinary excretion of 51 Cr was found. Statistically significant differences were also observed in the distribution of 51 Cr in the organism after administration of both valence states of the metal. (author)

  11. The Distance to M51

    Science.gov (United States)

    McQuinn, Kristen. B. W.; Skillman, Evan D.; Dolphin, Andrew E.; Berg, Danielle; Kennicutt, Robert

    2016-07-01

    Great investments of observing time have been dedicated to the study of nearby spiral galaxies with diverse goals ranging from understanding the star formation process to characterizing their dark matter distributions. Accurate distances are fundamental to interpreting observations of these galaxies, yet many of the best studied nearby galaxies have distances based on methods with relatively large uncertainties. We have started a program to derive accurate distances to these galaxies. Here we measure the distance to M51—the Whirlpool galaxy—from newly obtained Hubble Space Telescope optical imaging using the tip of the red giant branch method. We measure the distance modulus to be 8.58 ± 0.10 Mpc (statistical), corresponding to a distance modulus of 29.67 ± 0.02 mag. Our distance is an improvement over previous results as we use a well-calibrated, stable distance indicator, precision photometry in a optimally selected field of view, and a Bayesian Maximum Likelihood technique that reduces measurement uncertainties. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  12. Disappearance of the Supergiant Progenitor of SN 2011dh in M51

    Science.gov (United States)

    Van Dyk, Schuyler D.; Filippenko, Alexei V.; Fox, Ori; Kelly, Patrick; Smith, Nathan

    2013-03-01

    We report that in Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) observations at F555W and F814W with the UVIS channel, conducted on 2013 March 2 UT as part of our Cycle 20 Snapshot program GO-13029 (PI: A. Filippenko), we have discovered that the yellow supergiant star, identified by Van Dyk et al. (2011, ApJ, 741, L28) and Maund et al. (2011, MNRAS, 739, L37) at the position of the Type IIb SN 2011dh in M51, has vanished.

  13. Chromium-51-EDTA and technetium-99m-DTPA excretion for assessment of small bowel Crohn's disease

    International Nuclear Information System (INIS)

    O'Morain, C.; Chervu, L.; Milstein, D.M.; Das, K.M.

    1984-01-01

    In the present study, 4 patients with radiologically documented Crohn's disease were given 100 μCi of Cr-51-EDTA and 5 mCi of Tc-99m-DTPA together orally in 10ml of water, and urine was collected during the following 24 hr period. Sequential imaging of the stomach and the GI tract was done with a LFOV gamma camera at 10 min intervals until the activity cleared the small bowel. The images failed to show any localization of the activity in any disease process and no extraintestinal accumulation site was observed scintigraphically. Mean 24 hr urinary excretion for Tc-99m-DTPA was 4.8 +- 2.6% comparable to that of Cr-51-EDTA in these patients. This study suggests that a comparable oral dose of Tc-99m-DTPA could be substituted for Cr-51-EDTA as a far more readily available agent for documenting small bowel Crohn's disease by quantitative assessment of its urinary excretion

  14. Radioactivity of {sup 51}Cr in stainless steel collected from residences in the JCO neighborhood

    Energy Technology Data Exchange (ETDEWEB)

    Endo, S. E-mail: endos@ipc.hiroshima-u.ac.jp; Tosaki, N.; Shizuma, K.; Ishikawa, M.; Takada, J.; Suga, S.; Kitagawa, K.; Hoshi, M

    2000-08-01

    Stainless-steel (SS) samples activated by fission neutrons from the JCO criticality accident have been measured by low-background germanium spectrometers. The SS-samples, comprising 14 spoons and 4 other items, were collected from residences located at 130-700 m from the JCO site. Five SS-samples from within a ground distance of 400 m from JCO were identified as containing {sup 51}Cr activity, which was produced by the {sup 50}Cr(n, {gamma}){sup 51}Cr reaction. The chromium specific activities of {sup 51}Cr/Cr are preliminarily obtained to be 0.45-0.04 Bq/g-Cr for the 5 samples collected at 130-400 m distance.

  15. 22 CFR 192.51 - Death benefit.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Death benefit. 192.51 Section 192.51 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Compensation for Disability or Death § 192.51 Death benefit. (a) The Secretary of State or Agency Head may provide for payment...

  16. Contribution to the study of the red blood cells labelled with chromium-51 and technetium-99 m

    International Nuclear Information System (INIS)

    Canine, M.S.

    1983-01-01

    Although the bindings of Cr-51 and Tc-99 m were both in the β chain of hemoglobin molecule, the results obtained after previous incubations of the RBC with chromium and technetium, and the determinations of the efficiency of the labeling of RBC showed that the points of fixing of chromium and technetium with β chain of hemoglobin were probably different. The observations through the optic microscope allowed the verification that, at the concentration of 100 mg/ml of Cr-50, there were morphologic in the RBC. These modifications were not found after the other treatments. The comparison between scintigraphy obtained with Tc-99 m or Cr-51 RBC suggested that the technique which employs Tc-99 m can be more adequate than the one with Cr-51. (author)

  17. DYNAMICALLY DRIVEN EVOLUTION OF THE INTERSTELLAR MEDIUM IN M51

    International Nuclear Information System (INIS)

    Koda, Jin; Scoville, Nick; Potts, Ashley E.; Carpenter, John M.; Corder, Stuartt A.; Patience, Jenny; Sargent, Anneila I.; Sawada, Tsuyoshi; La Vigne, Misty A.; Vogel, Stuart N.; White, Stephen M.; Zauderer, B. Ashley; Pound, Marc W.; Wright, Melvyn C. H.; Plambeck, Richard L.; Bock, Douglas C. J.; Hawkins, David; Hodges, Mark; Lamb, James W.; Kemball, Athol

    2009-01-01

    Massive star formation occurs in giant molecular clouds (GMCs); an understanding of the evolution of GMCs is a prerequisite to develop theories of star formation and galaxy evolution. We report the highest-fidelity observations of the grand-design spiral galaxy M51 in carbon monoxide (CO) emission, revealing the evolution of GMCs vis-a-vis the large-scale galactic structure and dynamics. The most massive GMCs (giant molecular associations (GMAs)) are first assembled and then broken up as the gas flow through the spiral arms. The GMAs and their H 2 molecules are not fully dissociated into atomic gas as predicted in stellar feedback scenarios, but are fragmented into smaller GMCs upon leaving the spiral arms. The remnants of GMAs are detected as the chains of GMCs that emerge from the spiral arms into interarm regions. The kinematic shear within the spiral arms is sufficient to unbind the GMAs against self-gravity. We conclude that the evolution of GMCs is driven by large-scale galactic dynamics-their coagulation into GMAs is due to spiral arm streaming motions upon entering the arms, followed by fragmentation due to shear as they leave the arms on the downstream side. In M51, the majority of the gas remains molecular from arm entry through the interarm region and into the next spiral arm passage.

  18. A deep NuSTAR observation of M51: Investigating its Compton-thick nucleus, LINER companion and ULXs above 10 keV

    Science.gov (United States)

    Brightman, Murray; Annuar, Ady; Alexander, David M.; Earnshaw, Hannah; Gandhi, Poshak; Hornschemeier, Ann E.; Lehmer, Bret; Ptak, Andrew; Rangelov, Blagoy; Roberts, Tim P.; Stern, Daniel; Zezas, Andreas

    2017-08-01

    We present the results from a deep 200ks observation of M51 with NuSTAR. This observation was taken simultaneously with Chandra to provide soft-X-ray-coverage as well as to resolve the different point sources. We detect the Compton-thick nucleus of M51a, the LINER nucleus of M51b and several ultraluminous X-ray sources located in the galaxies above 10 keV. From X-ray torus modeling, we find that the covering factor of the torus in the nucleus of M51a is ~40% and supports a decline in the obscured fration at low X-ray luminosities. We find that the X-ray spectrum of the intermediate mass black hole candidate, ULX-7, is consistent with a power-law up to high energies, supporting its IMBH status. We further resolve the nucleus of M51b into two X-ray sources with Chandra, and measure its X-ray luminosity.

  19. Chromium 51 EDTA/technetium 99m MDP plasma ratio to measure total skeletal function

    Energy Technology Data Exchange (ETDEWEB)

    Nisbet, A.P.; Edwards, S.; Lazarus, C.R.; Malamitsi, J.; Maisey, M.N.; Mashiter, G.D.; Winn, P.J. (Guy' s Hospital, London (UK))

    1984-08-01

    A method is described for the quantitation of total skeletal activity during bone scans. The method requires a single plasma sample only, taken at the time of imaging. The ratio of % injected dose of /sup 51/Cr EDTA to that of /sup 99/Tcsup(m) MDP is calculated from this sample following combined injection of the two radiopharmaceuticals. The /sup 51/Cr EDTA level corrects for the glomerular filtration of /sup 99/Tcsup(m) MDP. Using this method, which only requires a gamma counter, significant differences from normal controls have been shown in patients with osteomalacia, renal osteodystrophy, Paget's disease and hypercalcaemia. The method provides routine quantitative data to add to the imaging information in the bone scan.

  20. 27 CFR 6.51 - General.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false General. 6.51 Section 6.51 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Paying for Advertising, Display Or Distribution Service...

  1. Analogy to Derive an Extended Pythagorean Theorem to ''N'' Dimensions

    Directory of Open Access Journals (Sweden)

    Acosta-Robledo J.U.

    2012-01-01

    Full Text Available This article demonstrates that it is possible to extend the Pythagorean Theorem to ''N'' dimensions. This demonstration is mainly done based on linear algebra, especially in the vector product of ''N'' dimensions.

  2. 24 CFR 51.302 - Coverage.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Coverage. 51.302 Section 51.302 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... significantly prolongs the physical or economic life of existing facilities or which, in the case of Accident...

  3. REGIONAL VARIATIONS IN THE DENSE GAS HEATING AND COOLING IN M51 FROM HERSCHEL FAR-INFRARED SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Parkin, T. J.; Wilson, C. D.; Schirm, M. R. P.; Foyle, K. [Department of Physics and Astronomy, McMaster University, Hamilton, Ontario, L8S 4M1 (Canada); Baes, M.; De Looze, I. [Sterrenkundig Observatorium, Universiteit Gent, Krijgslaan 281 S9, B-9000 Gent (Belgium); Boquien, M.; Boselli, A. [Laboratoire d' Astrophysique de Marseille-LAM, Université d' Aix-Marseille and CNRS, UMR7326, 38 rue F. Joliot-Curie, F-13388 Marseille Cedex 13 (France); Cooray, A. [Department of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Cormier, D. [Institut für Theoretische Astrophysik, Zentrum für Astronomie der Universität Heidelberg, Albert-Ueberle Str. 2, D-69120 Heidelberg (Germany); Karczewski, O. Ł. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Lebouteiller, V.; Madden, S. C.; Sauvage, M. [CEA, Laboratoire AIM, Irfu/SAp, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Roussel, H. [Institut d' Astrophysique de Paris, UMR7095 CNRS, Université Pierre and Marie Curie, 98 bis Boulevard Arago, F-75014 Paris (France); Spinoglio, L., E-mail: parkintj@mcmaster.ca [Istituto di Astrofisica e Planetologia Spaziali, INAF-IAPS, Via Fosso del Cavaliere 100, I-00133 Roma (Italy)

    2013-10-20

    We present Herschel PACS and SPIRE spectroscopy of the most important far-infrared cooling lines in M51, [C II](158 μm), [N II](122 and 205 μm), [O I](63 and 145 μm), and [O III](88 μm). We compare the observed flux of these lines with the predicted flux from a photon-dominated region model to determine characteristics of the cold gas such as density, temperature, and the far-ultraviolet (FUV) radiation field, G{sub 0}, resolving details on physical scales of roughly 600 pc. We find an average [C II]/F{sub TIR} of 4 × 10{sup –3}, in agreement with previous studies of other galaxies. A pixel-by-pixel analysis of four distinct regions of M51 shows a radially decreasing trend in both the FUV radiation field, G{sub 0}, and the hydrogen density, n, peaking in the nucleus of the galaxy, and then falling off out to the arm and interarm regions. We see for the first time that the FUV flux and gas density are similar in the differing environments of the arm and interarm regions, suggesting that the inherent physical properties of the molecular clouds in both regions are essentially the same.

  4. RAD51AP2, a novel vertebrate- and meiotic-specific protein, sharesa conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51

    Energy Technology Data Exchange (ETDEWEB)

    Kovalenko, Oleg V.; Wiese, Claudia; Schild, David

    2006-07-25

    Many interacting proteins regulate and/or assist the activities of RAD51, a recombinase which plays a critical role in both DNA repair and meiotic recombination. Yeast two-hybrid screening of a human testis cDNA library revealed a new protein, RAD51AP2 (RAD51 Associated Protein 2), that interacts strongly with RAD51. A full-length cDNA clone predicts a novel vertebrate specific protein of 1159 residues, and the RAD51AP2 transcript was observed only in meiotic tissue (i.e. adult testis and fetal ovary), suggesting a meiotic-specific function for RAD51AP2. In HEK293 cells the interaction of RAD51 with an ectopically-expressed recombinant large fragment of RAD51AP2 requires the C-terminal 57 residues of RAD51AP2. This RAD51-binding region shows 81% homology to the C-terminus of RAD51AP1/PIR51, an otherwise totally unrelated RAD51-binding partner that is ubiquitously expressed. Analyses using truncations and point mutations in both RAD51AP1 and RAD51AP2 demonstrate that these proteins use the same structural motif for RAD51 binding. RAD54 shares some homology with this RAD51-binding motif, but this homologous region plays only an accessory role to the adjacent main RAD51-interacting region, which has been narrowed here to 40 amino acids. A novel protein, RAD51AP2, has been discovered that interacts with RAD51 through a C-terminal motif also present in RAD51AP1.

  5. Transformational plane geometry

    CERN Document Server

    Umble, Ronald N

    2014-01-01

    Axioms of Euclidean Plane Geometry The Existence and Incidence Postulates The Distance and Ruler Postulates The Plane Separation Postulate The Protractor Postulate The Side-Angle-Side Postulate and the Euclidean Parallel Postulate Theorems of Euclidean Plane Geometry The Exterior Angle Theorem Triangle Congruence Theorems The Alternate Interior Angles Theorem and the Angle Sum Theorem Similar Triangles Introduction to Transformations, Isometries, and Similarities Transformations Isometries and SimilaritiesAppendix: Proof of Surjectivity Translations, Rotations, and Reflections Translations Rotations Reflections Appendix: Geometer's Sketchpad Commands Required by Exploratory Activities Compositions of Translations, Rotations, and Reflections The Three Points Theorem Rotations as Compositions of Two Reflections Translations as Compositions of Two Halfturns or Two Reflections The Angle Addition Theorem Glide Reflections Classification of Isometries The Fundamental Theorem and Congruence Classification of Isometr...

  6. Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51.

    Directory of Open Access Journals (Sweden)

    Shamila S Gunatilleke

    Full Text Available Chagas Disease, a WHO- and NIH-designated neglected tropical disease, is endemic in Latin America and an emerging infection in North America and Europe as a result of population moves. Although a major cause of morbidity and mortality due to heart failure, as well as inflicting a heavy economic burden in affected regions, Chagas Disease elicits scant notice from the pharmaceutical industry because of adverse economic incentives. The discovery and development of new routes to chemotherapy for Chagas Disease is a clear priority.The similarity between the membrane sterol requirements of pathogenic fungi and those of the parasitic protozoon Trypanosoma cruzi, the causative agent of Chagas human cardiopathy, has led to repurposing anti-fungal azole inhibitors of sterol 14α-demethylase (CYP51 for the treatment of Chagas Disease. To diversify the therapeutic pipeline of anti-Chagasic drug candidates we exploited an approach that included directly probing the T. cruzi CYP51 active site with a library of synthetic small molecules. Target-based high-throughput screening reduced the library of ∼104,000 small molecules to 185 hits with estimated nanomolar K(D values, while cross-validation against T. cruzi-infected skeletal myoblast cells yielded 57 active hits with EC(50 <10 µM. Two pools of hits partially overlapped. The top hit inhibited T. cruzi with EC(50 of 17 nM and was trypanocidal at 40 nM.The hits are structurally diverse, demonstrating that CYP51 is a rather permissive enzyme target for small molecules. Cheminformatic analysis of the hits suggests that CYP51 pharmacology is similar to that of other cytochromes P450 therapeutic targets, including thromboxane synthase (CYP5, fatty acid ω-hydroxylases (CYP4, 17α-hydroxylase/17,20-lyase (CYP17 and aromatase (CYP19. Surprisingly, strong similarity is suggested to glutaminyl-peptide cyclotransferase, which is unrelated to CYP51 by sequence or structure. Lead compounds developed by pharmaceutical

  7. Radioimmunoscintigraphy of experimental internal carotid arterial thrombi in dogs with 99mTc-labelled monoclonal anti-activated platelet antibody SZ-51

    International Nuclear Information System (INIS)

    Bao Shiyao; Li Wen; He Guangren; Shao Guofu; Zhang Zhilin; Wu Jinchang

    1995-05-01

    The capacity of McAbSZ-51, which is specific for an α-granule membrane protein (GMP-140) expressed on the surface of activated platelets, to bind to the grafted human thrombus in rabbits was studied. The feasibility of imaging thrombus with 99m Tc-labelled McAbSZ-51 in the internal carotid artery of dog was also explored. The results showed that McAbSZ-51 could bind to the grafted human thrombus in rabbits. The thrombus in internal carotid artery was clearly discerned at 2 to 6 h after injection of 99m Tc-SZ-51, with the optimal imaging time at 2 to 4 h after injection. The radioactivity ratio of thrombus to blood was 6.03 +- 1.09 at 6 to 8 h after injection. It is thus concluded that by using the 99m Tc-labelled McAbSZ-51, the early and specific detection of thrombi formed in vivo was fairly possible and feasible. (3 figs., 1 tab.)

  8. 19 CFR 210.51 - Period for concluding investigation.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Period for concluding investigation. 210.51 Section 210.51 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Determinations and Actions Taken § 210.51 Period for...

  9. SPIRAL STRUCTURE OF M51 - DISTRIBUTION AND KINEMATICS OF THE ATOMIC AND IONIZED HYDROGEN

    NARCIS (Netherlands)

    TILANUS, RPJ; ALLEN, RJ

    The atomic hydrogen (H I) and the H-alpha emission lines in the grand-design spiral galaxy M51 have been observed with the Westerbork Synthesis Radio Telescope and the TAURUS Fabry-Perot imaging spectrometer, respectively. Across the inner spiral arms significant tangential and radial velocity

  10. 25 CFR 23.51 - Grant carry-over authority.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Grant carry-over authority. 23.51 Section 23.51 Indians... Uniform Grant Administration Provisions and Requirements § 23.51 Grant carry-over authority. Unless... two years beyond the initial grant funding period and must be utilized only for the intent, purpose...

  11. 19 CFR 146.51 - Customs control of merchandise.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Customs control of merchandise. 146.51 Section 146.51 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) FOREIGN TRADE ZONES Handling of Merchandise in a Zone § 146.51 Customs...

  12. 26 CFR 1.381(c)(5)-1 - Inventories.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Inventories. 1.381(c)(5)-1 Section 1.381(c)(5)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Insolvency Reorganizations § 1.381(c)(5)-1 Inventories. (a) Carryover requirement—(1...

  13. On the Spatially Resolved Star Formation History in M51. I. Hybrid UV+IR Star Formation Laws and IR Emission from Dust Heated by Old Stars

    Science.gov (United States)

    Eufrasio, R. T.; Lehmer, B. D.; Zezas, A.; Dwek, E.; Arendt, R. G.; Basu-Zych, A.; Wiklind, T.; Yukita, M.; Fragos, T.; Hornschemeier, A. E.; Markwardt, L.; Ptak, A.; Tzanavaris, P.

    2017-12-01

    We present LIGHTNING, a new spectral energy distribution fitting procedure, capable of quickly and reliably recovering star formation history (SFH) and extinction parameters. The SFH is modeled as discrete steps in time. In this work, we assumed lookback times of 0-10 Myr, 10-100 Myr, 0.1-1 Gyr, 1-5 Gyr, and 5-13.6 Gyr. LIGHTNING consists of a fully vectorized inversion algorithm to determine SFH step intensities and combines this with a grid-based approach to determine three extinction parameters. We apply our procedure to the extensive far-UV-to-far-IR photometric data of M51, convolved to a common spatial resolution and pixel scale, and make the resulting maps publicly available. We recover, for M51a, a peak star formation rate (SFR) between 0.1 and 5 Gyr ago, with much lower star formation activity over the past 100 Myr. For M51b, we find a declining SFR toward the present day. In the outskirt regions of M51a, which includes regions between M51a and M51b, we recover an SFR peak between 0.1 and 1 Gyr ago, which corresponds to the effects of the interaction between M51a and M51b. We utilize our results to (1) illustrate how UV+IR hybrid SFR laws vary across M51 and (2) provide first-order estimates for how the IR luminosity per unit stellar mass varies as a function of the stellar age. From the latter result, we find that IR emission from dust heated by stars is not always associated with young stars and that the IR emission from M51b is primarily powered by stars older than 5 Gyr.

  14. 40 CFR 51.355 - Test frequency and convenience.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Test frequency and convenience. 51.355 Section 51.355 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Requirements § 51.355 Test frequency and convenience. (a) The performance standards for I/M programs assume an...

  15. Spiral Structure and Global Star Formation Processes in M 51

    Science.gov (United States)

    Gruendl, Robert A.

    1994-12-01

    The nearby grand design spiral galaxy, M 51, is an obvious proving ground for studies of spiral structure and large scale star formation processes. New near--infrared observations of M 51 made with COB (Cryogenic Optical Bench) on the Kitt Peak 1.3m allow us to examine the stellar distribution and the young star formation regions as well as probe regions of high extinction such as dust lanes. We also present an analysis of the kinematics of the ionized gas observed with the Maryland--Caltech Imaging Fabry Perot. The color information we derive from the near--infrared bands provides a more accurate tracer of extinction than optical observations. We find that the dust extinction and CO emission in the arms are well correlated. Our kinematic data show unambiguously that these dense gas concentrations are associated with kinematic perturbations. In the inner disk, these perturbations are seen to be consistent with the streaming motions predicted by classical density wave theory. The dust lanes, and presumably the molecular arms, form a narrow ridge that matches these velocity perturbations wherever the viewing angle is appropriate. This interpretation requires that the corotation radius be inward of the outer tidal arms. The outer tidal arms however show streaming velocities of the sign that would be expected interior to the corotation point. This can be reconciled if the outer arms are part of a second spiral pattern, most likely due to the interaction with the companion NGC 5195. The near--infrared observations also show emission from the massive star forming regions. These observations are less affected by extinction than optical observations of H II regions and show clearly that the sites of massive star formation are correlated with but downstream from the concentrations of dense molecular material. This provides clear evidence that the ISM has been organized by the streaming motions which have in turn triggered massive star formation.

  16. 40 CFR 51.356 - Vehicle coverage.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Vehicle coverage. 51.356 Section 51.356....356 Vehicle coverage. The performance standard for enhanced I/M programs assumes coverage of all 1968 and later model year light duty vehicles and light duty trucks up to 8,500 pounds GVWR, and includes...

  17. Sequencing and Analysis of the Pseudomonas fluorescens GcM5-1A Genome: A Pathogen Living in the Surface Coat of Bursaphelenchus xylophilus.

    Directory of Open Access Journals (Sweden)

    Kai Feng

    Full Text Available It is known that several bacteria are adherent to the surface coat of pine wood nematode (Bursaphelenchus xylophilus, but their function and role in the pathogenesis of pine wilt disease remains debatable. The Pseudomonas fluorescens GcM5-1A is a bacterium isolated from the surface coat of pine wood nematodes. In previous studies, GcM5-1A was evident in connection with the pathogenicity of pine wilt disease. In this study, we report the de novo sequencing of the GcM5-1A genome. A 600-Mb collection of high-quality reads was obtained and assembled into sequence contigs spanning a 6.01-Mb length. Sequence annotation predicted 5,413 open reading frames, of which 2,988 were homologous to genes in the other four sequenced P. fluorescens isolates (SBW25, WH6, Pf0-1 and Pf-5 and 1,137 were unique to GcM5-1A. Phylogenetic studies and genome comparison revealed that GcM5-1A is more closely related to SBW25 and WH6 isolates than to Pf0-1 and Pf-5 isolates. Towards study of pathogenesis, we identified 79 candidate virulence factors in the genome of GcM5-1A, including the Alg, Fl, Waa gene families, and genes coding the major pathogenic protein fliC. In addition, genes for a complete T3SS system were identified in the genome of GcM5-1A. Such systems have proved to play a critical role in subverting and colonizing the host organisms of many gram-negative pathogenic bacteria. Although the functions of the candidate virulence factors need yet to be deciphered experimentally, the availability of this genome provides a basic platform to obtain informative clues to be addressed in future studies by the pine wilt disease research community.

  18. Multiband counterparts of two eclipsing ultraluminous X-ray sources in M 51

    Science.gov (United States)

    Urquhart, R.; Soria, R.; Johnston, H. M.; Pakull, M. W.; Motch, C.; Schwope, A.; Miller-Jones, J. C. A.; Anderson, G. E.

    2018-04-01

    We present the discovery and interpretation of ionized nebulae around two ultraluminous X-ray sources in M 51; both sources share the rare property of showing X-ray eclipses by their companion stars and are therefore prime targets for follow-up studies. Using archival Hubble Space Telescope images, we found an elongated, 100-pc-long emission-line structure associated with one X-ray source (CXOM51 J132940.0+471237; ULX-1 for simplicity), and a more circular, ionized nebula at the location of the second source (CXOM51 J132939.5+471244; ULX-2 for simplicity). We observed both nebulae with the Large Binocular Telescope's Multi-Object Double Spectrograph. From our analysis of the optical spectra, we argue that the gas in the ULX-1 bubble is shock-ionized, consistent with the effect of a jet with a kinetic power of ≈2 × 1039 erg s-1. Additional X-ray photoionization may also be present, to explain the strength of high-ionization lines such as He II λ4686 and [Ne V] λ3426. On the other hand, the emission lines from the ULX-2 bubble are typical for photoionization by normal O stars suggesting that the nebula is actually an H II region not physically related to the ULX but is simply a chance alignment. From archival Very Large Array data, we also detect spatially extended, steep-spectrum radio emission at the location of the ULX-1 bubble (consistent with its jet origin), but no radio counterpart for ULX-2 (consistent with the lack of shock-ionized gas around that source).

  19. A production method for Cr-51 at IEN's cyclotron

    International Nuclear Information System (INIS)

    Bastos, M.A.V.; Britto, J.L.Q. de; Vinagre, U.M.; Silva, A.G. da.

    1989-01-01

    Thick target yields for the reactions 51 V(p,n) 51 Cr and 51 V(d,2n) 51 Cr were measured and compared with literature values. The excitation function for the 51 V(p,n) 51 Cr reaction was also measured. A method for the production and separation of this radioisotope was developed via the 51 V(p,n) 51 Cr reaction and a combination of Fe +3 co-precipitation and an anion exchange technique using a Dowex 1x8(100-200 mesh) resin in hydrochloric acid medium [pt

  20. 46 CFR 188.10-51 - Ocean.

    Science.gov (United States)

    2010-10-01

    ... Terms Used in This Subchapter § 188.10-51 Ocean. Under this designation shall be included all vessels navigating the waters of any ocean, or the Gulf of Mexico more than 20 nautical miles offshore. ... 46 Shipping 7 2010-10-01 2010-10-01 false Ocean. 188.10-51 Section 188.10-51 Shipping COAST GUARD...

  1. A production method for Cr-51 at IEN's cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Bastos, M A.V.; Britto, J L.Q. de; Vinagre, U M; Silva, A.G. da [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia

    1990-01-01

    Thick target yields for the reactions {sup 51} V(p,n){sup 51} Cr and {sup 51} V(d, 2 n){sup 51} Cr were measured and compared with literature values. The excitation function for the {sup 51} V(p,n){sup 51} Cr reaction was also measured. A method for the production and separation of this radioisotope was developed via the {sup 51} V(p,n){sup 51} Cr reaction and a combination of Fe+3 coprecipitation and an anion exchange technique using a Dowex 1X8(100-200 mesh) resin in hydrochloric acid medium. (author).

  2. A production method for Cr-51 at IEN's cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Bastos, M A.V.; Britto, J L.Q. de; Vinagre, U M; Silva, A.G. da [Instituto de Engenharia Nuclear, Rio de Janeiro (Brazil). Dept. de Fisica

    1990-01-01

    Thick target yields for the reactions {sup 51}V(p,n){sup 51}Cr and {sup 51}V(d,2n){sup 51}Cr were measured and compared with literature values. The excitation function for the {sup 51}V(p,n){sup 51}Cr reaction was also measured. A method for the production and separation of this radioisotope was developed via the {sup 51}V(p,n){sup 51}Cr reaction and a combination of Fe{sup +3} coprecipitation and an anion exchange technique using a Dowex 1X8 (100-200 mesh) resin in hydrochloric acid medium. (orig.).

  3. The PdBI arcsecond whirlpool survey (PAWS): Environmental dependence of giant molecular cloud properties in M51

    International Nuclear Information System (INIS)

    Colombo, Dario; Hughes, Annie; Schinnerer, Eva; Meidt, Sharon E.; Leroy, Adam K.; Pety, Jérôme; Dumas, Gaëlle; Schuster, Karl F.; Dobbs, Clare L.; García-Burillo, Santiago; Thompson, Todd A.; Kramer, Carsten

    2014-01-01

    Using data from the PdBI Arcsecond Whirlpool Survey (PAWS), we have generated the largest extragalactic giant molecular cloud (GMC) catalog to date, containing 1507 individual objects. GMCs in the inner M51 disk account for only 54% of the total 12 CO(1-0) luminosity of the survey, but on average they exhibit physical properties similar to Galactic GMCs. We do not find a strong correlation between the GMC size and velocity dispersion, and a simple virial analysis suggests that ∼30% of GMCs in M51 are unbound. We have analyzed the GMC properties within seven dynamically motivated galactic environments, finding that GMCs in the spiral arms and in the central region are brighter and have higher velocity dispersions than inter-arm clouds. Globally, the GMC mass distribution does not follow a simple power-law shape. Instead, we find that the shape of the mass distribution varies with galactic environment: the distribution is steeper in inter-arm region than in the spiral arms, and exhibits a sharp truncation at high masses for the nuclear bar region. We propose that the observed environmental variations in the GMC properties and mass distributions are a consequence of the combined action of large-scale dynamical processes and feedback from high-mass star formation. We describe some challenges of using existing GMC identification techniques for decomposing the 12 CO(1-0) emission in molecule-rich environments, such as M51's inner disk.

  4. Spiral arm amplitude variations and pattern speeds in the grand design galaxies M51, M81, and M100

    International Nuclear Information System (INIS)

    Elmegreen, B.G.; Seiden, P.E.; Elmegreen, D.M.

    1989-01-01

    In the modal theory of galactic spiral structure, the amplitude of a prominent two-arm spiral pattern should oscillate slightly with galactocentric distance because of an interference between the outward and inward propagating waves. In the stellar dynamical theory, the spiral arm amplitudes should oscillate because of differential crowding near and between wave-orbit resonances. Two and three cycles of such oscillations have been found in computer-enhanced images at B and I passbands of the grand design galaxies M81 and M100, respectively, and what is probably one cycle of such an amplitude variation in M51. These three galaxies are the most symmetric and global of the two-arm spirals in the near-IR survey of Elmegreen (1981), so the occurrence of such spiral amplitude oscillations could be common among galaxies of this type. The positions of the features discussed are used to suggest possible arm pattern speeds. 23 refs

  5. 18 CFR 415.51 - Prior non-conforming structures.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Prior non-conforming structures. 415.51 Section 415.51 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... damaged by any means, including a flood, to the extent of 50 percent or more of its market value at that...

  6. 36 CFR 51.51 - What special terms must I know to understand leasehold surrender interest?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false What special terms must I know to understand leasehold surrender interest? 51.51 Section 51.51 Parks, Forests, and Public... Interest § 51.51 What special terms must I know to understand leasehold surrender interest? To understand...

  7. The resolved star formation history of M51a through successive Bayesian marginalization

    Science.gov (United States)

    Martínez-García, Eric E.; Bruzual, Gustavo; Magris C., Gladis; González-Lópezlira, Rosa A.

    2018-02-01

    We have obtained the time and space-resolved star formation history (SFH) of M51a (NGC 5194) by fitting Galaxy Evolution Explorer (GALEX), Sloan Digital Sky Survey and near-infrared pixel-by-pixel photometry to a comprehensive library of stellar population synthesis models drawn from the Synthetic Spectral Atlas of Galaxies (SSAG). We fit for each space-resolved element (pixel) an independent model where the SFH is averaged in 137 age bins, each one 100 Myr wide. We used the Bayesian Successive Priors (BSP) algorithm to mitigate the bias in the present-day spatial mass distribution. We test BSP with different prior probability distribution functions (PDFs); this exercise suggests that the best prior PDF is the one concordant with the spatial distribution of the stellar mass as inferred from the near-infrared images. We also demonstrate that varying the implicit prior PDF of the SFH in SSAG does not affect the results. By summing the contributions to the global star formation rate of each pixel, at each age bin, we have assembled the resolved SFH of the whole galaxy. According to these results, the star formation rate of M51a was exponentially increasing for the first 10 Gyr after the big bang, and then turned into an exponentially decreasing function until the present day. Superimposed, we find a main burst of star formation at t ≈ 11.9 Gyr after the big bang.

  8. Proofs and generalizations of the pythagorean theorem

    Directory of Open Access Journals (Sweden)

    Lialda B. Cavalcanti

    2011-01-01

    Full Text Available This article explores a topic developed by a group of researchers of the Science and Technology Teaching School of Instituto Federal de Pernambuco, Brazil (IFPE, in assistance to the development of the Mathematics Practical and Teaching Laboratory of the distance learning Teaching Licensure, financed by the Universidad Abierta de Brasil. In this article, we describe the peculiarities present in the proofs of the Pythagorean theorem with the purpose of illustrating some of these methods. The selection of these peculiarities was founded and based on the comparison of areas by means of the superimposition of geometrical shapes and used several different class resources. Some generalizations of this important theorem in mathematical problem-solving are also shown.

  9. 22 CFR 226.51 - Monitoring and reporting program performance.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Monitoring and reporting program performance. 226.51 Section 226.51 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF... more frequently than quarterly or, less frequently than annually. Annual reports shall be due 90...

  10. 51Cr release and oxidative stress in the lens

    International Nuclear Information System (INIS)

    Stewart-DeHaan, P.J.; Sanwal, M.; Creighton, M.O.; Inch, W.R.; Trevithick, J.R.

    1989-01-01

    Examination of the opaque areas of human cortical cataracts has shown that a large portion of the opacity could be attributed to the globules found there. We tested models involving globule formation as a result of oxidative damage to rat lens cells in culture and whole chick embryo lenses. When cell monolayers from a lens cell line were exposed to oxidizing conditions they developed globules on the cell surface. The cells were protected from damage by the addition of glutathione and vitamin C. Thirteen-day chick embryo lenses were also incubated in oxidizing conditions and the amount of cellular damage was assessed using a chromium-51 release assay we have developed. After 24 hr the percent 51Cr in the medium increased by an average of 20% as a result of 10 mM hydrogen peroxide treatment. The addition of the 10 mM vitamin C to the hydrogen peroxide significantly reduced the 51Cr leakage to the control level. Light microscopy of sections of the lens showed a breakdown of the equatorial fibre arrangement in the presence of H2O2, while addition of vitamin C restored the fibre organization to almost normal. The findings suggest that oxidative stress is an important step in cataractogenesis and point towards the use of water soluble antioxidants as protective agents

  11. MAPPING THE RECENT STAR FORMATION HISTORY OF THE DISK OF M51

    International Nuclear Information System (INIS)

    Kaleida, Catherine; Scowen, Paul A.

    2010-01-01

    Using data acquired as part of a unique Hubble Heritage imaging program of broadband colors of the interacting spiral system M51/NGC 5195, we have conducted a photometric study of the stellar associations across the entire disk of the galaxy in order to assess trends in size, luminosity, and local environment associated with the recent star formation (SF) activity in the system. Starting with a sample of over 900 potential associations, we have produced color-magnitude and color-color diagrams for the 120 associations that were deemed to be single-aged. It has been found that main-sequence (MS) turnoffs are not evident for the vast majority of the stellar associations in our set, potentially due to the overlap of isochronal tracks at the high mass end of the MS, and the limited depth of our images at the distance of M51. In order to obtain ages for more of our sample, we produced model spectral energy distributions (SEDs) to fit to the data from the GALEXEV simple stellar population models of Bruzual and Charlot. These SEDs can be used to determine age, size, mass, metallicity, and dust content of each association via a simple χ 2 minimization to each association's B-, V-, and I-band fluxes. The derived association properties are mapped as a function of location, and recent trends in SF history of the galaxy are explored in light of these results. This work is the first phase in a program that will compare these stellar systems with their environments using ultraviolet data from the Galaxy Evolution Explorer and infrared data from Spitzer, and ultimately we plan to apply the same stellar population mapping methodology to other nearby face-on spiral galaxies.

  12. 27 CFR 4.51 - Exhibiting certificates to Government officials.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Exhibiting certificates to Government officials. 4.51 Section 4.51 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Requirements for...

  13. 21 CFR 1250.51 - Railroad conveyances; discharge of wastes.

    Science.gov (United States)

    2010-04-01

    ..., Center for Food Safety and Applied Nutrition, Manager, Interstate Travel Sanitation Sub-Program, HFF-312... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Railroad conveyances; discharge of wastes. 1250.51 Section 1250.51 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  14. Chromium-51-EDTA clearance in adults with a single-plasma sample.

    Science.gov (United States)

    Mårtensson, J; Groth, S; Rehling, M; Gref, M

    1998-12-01

    In 1996, a committee on renal clearance recommended a mean sojourn time-based methodology for single-sample determination of plasma clearance of 99mTc-diethylenetriamine pentaacetic acid (DTPA) to be used on adults if the patient's glomerular filtration rate (GFR) is suspected to be >30 ml/min. The main purpose of this study was to derive a mean sojourn time-based formula for calculation of 51Cr-ethylenediamine tetraacetic acid (EDTA) clearance in adults. Two groups of patients with 51Cr-EDTA clearance (Cl) between 16 and 172 ml/min were studied. In Group I (n = 46), reference Cl was determined as a multiplasma sample, single-injection method (ClSM). Sixteen blood samples were drawn from 0 until 5 hr after a single intravenous injection of 51Cr-EDTA. In Group II (n = 1046), reference Cl was determined by the Brøchner-Mortensen four-sample clearance method (ClBM). The plasma time-activity curves of Group I were used to derive two mean sojourn time-based formulas (Formulas 1 and 2) for calculation of a single-sample clearance. Formula 1 was derived from the entire time-activity curve, whereas the derivation of Formula 2 used only the final slope of the time-activity curve. The accuracy of the two formulas and the Christensen and Groth 99mTc-DTPA formula was tested on Group II. Chromium-51-EDTA Cl calculated by Formula 1 was almost identical to the Cl calculated by the reference Cl method (r = 0.982; SDdiff = 5.82 ml/min). Both 51Cr-EDTA Cl calculated by Formula 2 and by the 99mTc-DTPA formula showed close correlation with the reference method (r = 0.976, r = 0.985, respectively) but systematically overestimated GFR for the whole range of clearance values by 3.5 and 3.2 ml/min (ptime methodology. The determination is marginally more accurate (ptime-activity curve than from only the final slope. The single-sample formula derived for determination of 99mTc-DTPA Cl tends slightly to overestimate GFR if used to calculate 51Cr-EDTA Cl.

  15. Promotion of Homologous Recombination and Genomic Stability byRAD51AP1 via RAD51 Recombinase Enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Wiese, Claudia; Dray, Eloise; Groesser, Torsten; San Filippo,Joseph; Shi, Idina; Collins, David W.; Tsai, Miaw-Sheue; Williams,Gareth; Rydberg, Bjorn; Sung, Patrick; Schild, David

    2007-04-11

    Homologous recombination (HR) repairs chromosome damage and is indispensable for tumor suppression in humans. RAD51 mediates the DNA strand pairing step in HR. RAD51AP1 (RAD51 Associated Protein 1) is a RAD51-interacting protein whose function has remained elusive. Knockdown of RAD51AP1 in human cells by RNA interference engenders sensitivity to different types of genotoxic stress. Moreover, RAD51AP1-depleted cells are impaired for the recombinational repair of a DNA double-strand break and exhibit chromatid breaks both spontaneously and upon DNA damaging treatment. Purified RAD51AP1 binds dsDNA and RAD51, and it greatly stimulates the RAD51-mediated D-loop reaction. Biochemical and cytological results show that RAD51AP1 functions at a step subsequent to the assembly of the RAD51-ssDNA nucleoprotein filament. Our findings provide the first evidence that RAD51AP1 helps maintain genomic integrity via RAD51 recombinase enhancement.

  16. A miR-590/Acvr2a/Rad51b Axis Regulates DNA Damage Repair during mESC Proliferation

    Directory of Open Access Journals (Sweden)

    Qidong Liu

    2014-12-01

    Full Text Available Embryonic stem cells (ESCs enable rapid proliferation that also causes DNA damage. To maintain genomic stabilization during rapid proliferation, ESCs must have an efficient system to repress genotoxic stress. Here, we show that withdrawal of leukemia inhibitory factor (LIF, which maintains the self-renewal capability of mouse ESCs (mESCs, significantly inhibits the cell proliferation and DNA damage of mESCs and upregulates the expression of miR-590. miR-590 promotes single-strand break (SSB and double-strand break (DSB damage repair, thus slowing proliferation of mESCs without influencing stemness. miR-590 directly targets Activin receptor type 2a (Acvr2a to mediate Activin signaling. We identified the homologous recombination-mediated repair (HRR gene, Rad51b, as a downstream molecule of the miR-590/Acvr2a pathway regulating the SSB and DSB damage repair and cell cycle. Our study shows that a miR-590/Acvr2a/Rad51b signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.

  17. HIRFL Power Controller Based On RTX51

    International Nuclear Information System (INIS)

    Li Guihua; Qiao Weimin; Jing Lan; Liu Caihong

    2009-01-01

    This system is used to control HIRFL power. The design of system is based on RTX51 tiny OS. We developed programmes on the MSC1210. The HIRFL power controller software is adopted multitask structure. It can deal with multi-instruction in the same period. The article introduces designs of the hardware and the software in the HIRFL power controller. The last is the report of using. (authors)

  18. Production possibility of 51Mn via natV(3He,x)51Mn nuclear process for combined positron emission tomography and magnetic resonance imaging studies

    International Nuclear Information System (INIS)

    Szelecsenyi, F.; Kovacs, Z.; Suzuki, K.; Mukai, K.; Japan Steel Works, Yokohama

    2007-01-01

    Complete text of publication follows. It is very difficult to quantify the uptake kinetics and bio-distribution of magneto pharmaceuticals in humans using MRI (Magnetic Resonance Imaging). The well-know PET (Positron Emission Tomography) technique, however, could give a solution to this problem in the case of those MRI contrast agents that are based on manganese as paramagnetic contrast enhancer. Luckily manganese has a proper radioisotope, namely the 51 Mn (T 1/2 = 46.2 min, β + = 97%), which can be easily employed (in the form of 51 Mn-labelled contrast agents) for PET studies. Recently, for the production of this radioisotope proton and deuteron induced nuclear reactions were suggested using natural and enriched Cr targets, respectively. In this work we studied the nat V( 3 He,x) 51 Mn nuclear processes in detail from their respective threshold energies up to 40 MeV. For natural vanadium, the 51 V( 3 He,3n) 51 Mn reaction (natural isotopic composition of 51 V: 99.75%) forms the majority of the required radioisotope. The cross-sections were measured by the conventional stacked-foil method. Two stacks containing 10 and 8 pieces of thin natural V foils were irradiated in external collimated 3 He beams of the AVF-930 isochronous cyclotron of NIRS. Thin copper and titanium foils served as energy degraders. The activations lasted for 1 h with a beam current of 100 nA. The activity of the irradiated samples was measured without chemical separation by using the usual gamma-ray spectroscopy. Since the 51 Mn has a very weak gamma-line at 749 keV (Iγ=0.265%) its activity was measured via decay curve analysis of the annihilation peaks. We also measured the excitation functions of those reactions which form the major radio-contaminants i.e. 52m Mn (T 1/2 =21.1 min, Eγ=1434.068 keV(Iγ=98.3%)) and 52 Mn (T 1/2 = 5.591 d, Eγ=744.223 keV (Iγ=90%), Eγ=935.538 keV (Iγ=94.5%)). The excitation function curve of the nat V( 3 He,x) 51 Mn nuclear process shows one maximum of

  19. 51Cr diffusion in Zr-Sn alloys

    International Nuclear Information System (INIS)

    Nicolai, L.I.; Migoni, R.L.; Hojvat de Tendler, Ruth

    1982-01-01

    The 51 Cr volume diffusion in Zr-Sn alloys is measured in polycrystals with big grains by the thin-film method. The Sn content in the alloys ranges from 0.39% at to 6.66 % at. In the beta-phase the analysed temperature range is 982 deg C-1240 deg C. The Sn dehances the 51 Cr diffusion in beta-Zr, the effect being small but well defined. Assuming the formation of Sn-Cr dimers, the linear dehancement coefficient b and the parameters for the variation of b with temperature were calculated. The parameters Q and D o were calculated for the more diluted alloys and, upon application of the Zener theory for D o , a negative contribution to the activation entropy is found. Three experiments at different temperatures were performed in the alpha-phase. 51 Cr diffuses very fast in alpha-Zr-Sn. No definite correlation is found between the 51 Cr diffusivity and the increasing Sn concentration, probably due to the anisotropy of the alfa-phase. (M.E.L.) [es

  20. Science Library of Test Items. Volume Thirteen. Mastery Testing Program. [Mastery Tests Series 5.] Tests M51-M65.

    Science.gov (United States)

    New South Wales Dept. of Education, Sydney (Australia).

    As part of a series of tests to measure mastery of specific skills in the natural sciences, copies of tests 51 through 65 include: (51) interpreting atomic and mass numbers; (52) extrapolating from a geological map; (53) matching geological sections and maps; (54) identifying parts of the human eye; (55) identifying the functions of parts of a…

  1. EnviroAtlas - Durham, NC - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas ) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets ).

  2. EnviroAtlas - Portland, Maine - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  3. EnviroAtlas - Portland, ME - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  4. EnviroAtlas - Austin, TX - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. Vegetated cover is defined as Trees & Forest and Grass & Herbaceous. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  5. EnviroAtlas - Memphis, TN - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. Forest is defined as Trees & Forest and Woody Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  6. EnviroAtlas - Portland, OR - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area.This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (http:/www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  7. EnviroAtlas - Milwaukee, WI - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  8. EnviroAtlas - Pittsburgh, PA - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  9. EnviroAtlas - Fresno, CA - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area.This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  10. EnviroAtlas - Woodbine, Iowa - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area.This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  11. EnviroAtlas - Phoenix, AZ - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  12. EnviroAtlas - Phoenix, AZ - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  13. EnviroAtlas - Tampa, FL - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  14. EnviroAtlas - Woodbine, IA - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  15. EnviroAtlas - Milwaukee, WI - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  16. EnviroAtlas - Portland, OR - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (http:/www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  17. EnviroAtlas - Cleveland, OH - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. In this community, forest is defined as Trees & Forest and Woody Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas ) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  18. EnviroAtlas - Pittsburgh, PA - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  19. EnviroAtlas - Fresno, CA - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  20. EnviroAtlas - Durham, NC - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas ) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets ).

  1. EnviroAtlas - Paterson, NJ - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. EnviroAtlas defines tree buffer for this community as only trees and forest. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  2. EnviroAtlas - Tampa, FL - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  3. EnviroAtlas - Austin, TX - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. Forest is defined as Trees & Forest. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  4. 2018-05-05T10:34:51Z https://www.ajol.info/index.php/index/oai oai ...

    African Journals Online (AJOL)

    article/46923 2018-05-05T10:34:51Z eamj:ART Emotional And Behavioural Disorders In HIV Seropositive Adolescents In ... Almost two thirds (60.9%) of them were in the HIV/ AIDS clinical disease stage III or IV and were not on ARVs drugs.

  5. 19 CFR 133.51 - Relief from forfeiture or liquidated damages.

    Science.gov (United States)

    2010-04-01

    ... following conditions and such other conditions as may be specified by the appropriate Customs authority: (1... 19 Customs Duties 1 2010-04-01 2010-04-01 false Relief from forfeiture or liquidated damages. 133.51 Section 133.51 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY...

  6. 40 CFR 73.51 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false [Reserved] 73.51 Section 73.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Allowance Transfers § 73.51 [Reserved] ...

  7. 22 CFR 214.51 - Administrative review of denial for public access to records.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Administrative review of denial for public access to records. 214.51 Section 214.51 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADVISORY COMMITTEE MANAGEMENT Administrative Remedies § 214.51 Administrative review of denial for public access to...

  8. 7 CFR 1900.51 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Definitions. 1900.51 Section 1900.51 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... GENERAL Adverse Decisions and Administrative Appeals § 1900.51 Definitions. Act means the Federal Crop...

  9. 40 CFR 51.1000 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Definitions. 51.1000 Section 51.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS REQUIREMENTS FOR... Ambient Air Quality Standards § 51.1000 Definitions. The following definitions apply for purposes of this...

  10. 7 CFR 51.893 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.893 Section 51.893 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Table Grapes (European or Vinifera Type) 1 Definitions § 51.893 Firm. Firm means...

  11. 7 CFR 51.57 - Facilities.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Facilities. 51.57 Section 51.57 Agriculture... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.57 Facilities. Each packing plant shall be equipped with adequate sanitary facilities and accommodations, including but not...

  12. 14 CFR 93.51 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area § 93.51... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Applicability. 93.51 Section 93.51..., Terminal Area. [Doc. No. FAA-2002-13235, 68 FR 9795, Feb. 28, 2003] ...

  13. 7 CFR 51.900 - Sunburn.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Sunburn. 51.900 Section 51.900 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Table Grapes (European or Vinifera Type) 1 Definitions § 51.900 Sunburn. Sunburn...

  14. 45 CFR 86.51 - Employment.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Employment. 86.51 Section 86.51 Public Welfare... in Employment in Education Programs or Activities Prohibited § 86.51 Employment. (a) General. (1) No... subjected to discrimination in employment, or recruitment, consideration, or selection therefor, whether...

  15. HLA-B51 IN BEHÇET’S DISEASE

    Directory of Open Access Journals (Sweden)

    F Davatchi

    2008-12-01

    Full Text Available "nThere is some data in the literature on the association of HLA-B5 and some manifestations of Behçet's disease (BD, especially ocular lesions. We studied 433 patients to see if there was any relationship between B51 and the manifestations of the disease. Clinical manifestations of BD were compared in patients having HLA-B51 (155 patients and those lacking HLA-B51 (278 patients. Oral aphthosis, genital aphthosis, skin manifestations, joint manifestations, gastrointestinal manifestations, phlebitis and neurological manifestations showed no significant difference in patients with and without HLA-B51. Ophthalmologic manifestations were seen in 52% of patients having B51 and in 42% of patients lacking it (χ2: 4.451, P = 0.035. Considering different lesions of ocular manifestations separately, no significant difference was found regarding the presence or absence of B51. Pathergy phenomenon was detected in 55% of B51 positive patients and in 45% of B51 negative patients (χ2: 4.111, P = 0.043. It seems that HLA-B51 may play a role in the pathogenesis of Behçet's disease, but cannot be used as predictive value for the occurrence of organ involvement, except for the eye.

  16. Berkeley 51 Kümesinin Temel ve Astrofiziksel Parametrelerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    İnci Akkaya Oralhan

    2016-10-01

    Full Text Available Galaksimizin birinci çeyreğinde bulunan ve daha önce çok az çalışılmış açık yıldız kümelerinden biri olan Berkeley 51 kümesinin temel astrofiziksel ve yapısal parametreleri CCD UBV(RIC ve 2MASS JHKS verileri kullanılarak elde edilmiştir. Kümeye ait CCD UBV(RIC verileri Meksika’da bulunan San Pedro Martir Ulusal Gözlemevi’nden 84cm’lik teleskop ile alınmıştır. Küme üyeliklerinin belirlenmesinde ise PPMXL kataloğundaki öz hareket verileri kullanılmıştır. Buna küre bu küme için elde edilen limit yarıçap Rlim=2.5 yay dakikası, kızarma E(B-V=0.85±0.05 kadir, E(J-H=0.28±0.02 kadir, uzaklık modülü DM=(m-M0=10.66±0.04 pc, uzaklığı d=1355±27 pc ve logaritmik yaş log(A=9.54±0.03 Myıl olarak bulunmuştur. Küme için ilk kez bulunan metal ve ağır element bolluğu ise sırasıyla [Fe/H]=-0.38 ve Z=0.006 olarak elde edilmiştir.Anahtar kelimeler: Açık yıldız kümeleri-Berkeley 51

  17. Characterization of tank 51 sludge samples (HTF-51-17-44/ HTF-51-17-48) in support of sludge batch 10 processing

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-08-17

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) Engineering (SRR-E) to provide sample characterization and analyses of Tank 51 sludge samples in support of Sludge Batch (SB) 10. The two Tank 51 sludge samples were sampled and delivered to SRNL in May of 2017. These two tank 51 sludge samples were combined into one composite sample and analyzed for corrosion controls analytes, select radionuclides, chemical elements, density and weight percent total solids and aluminum hydroxides (gibbsite and boehmite) by x-ray diffraction.

  18. 7 CFR 51.1551 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.1551 Section 51.1551 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Potatoes 1 Definitions § 51.1551 Firm. Firm means that the potato is not shriveled...

  19. 7 CFR 51.696 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.696 Section 51.696 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... § 51.696 Firm. Firm as applied to common oranges, means that the fruit is not soft, or noticeably...

  20. 7 CFR 51.1353 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.1353 Section 51.1353 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Pears for Canning Definitions § 51.1353 Firm. Firm means that the pear is fairly solid and...

  1. 7 CFR 51.1006 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.1006 Section 51.1006 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Persian (Tahiti) Limes Definitions § 51.1006 Firm. Firm means that the fruit is not soft or...

  2. 7 CFR 51.1824 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.1824 Section 51.1824 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Florida Tangerines Definitions § 51.1824 Firm. Firm means that the flesh is not soft...

  3. 7 CFR 51.765 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.765 Section 51.765 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Florida Grapefruit Definitions § 51.765 Firm. Firm means that the fruit is not soft...

  4. 7 CFR 29.51 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Administration. 29.51 Section 29.51 Agriculture... INSPECTION Regulations Administration § 29.51 Administration. The Director is charged with the supervision of the Division and the performance of all duties assigned thereto in the administration of the Act...

  5. EnviroAtlas - Cleveland, OH - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. In this community, vegetated cover is defined as Trees & Forest, Grass & Herbaceous, Woody Wetlands, and Emergent Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas ) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  6. EnviroAtlas - Paterson, NJ - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. EnviroAtlas defines vegetated buffer for this community as trees and forest and grass and herbaceous. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  7. EnviroAtlas - Memphis, TN - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. Vegetated cover is defined as Trees & Forest, Grass & Herbaceous, Woody Wetlands, and Emergent Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  8. 7 CFR 51.634 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.634 Section 51.634 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...) Definitions § 51.634 Firm. Firm means that the fruit is not soft, or noticeably wilted or flabby, and the skin...

  9. 38 CFR 51.210 - Administration.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Administration. 51.210 Section 51.210 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) PER DIEM FOR NURSING HOME CARE OF VETERANS IN STATE HOMES Standards § 51.210 Administration. A facility must be...

  10. 7 CFR 51.911 - Container.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Container. 51.911 Section 51.911 Agriculture... Standards for Grades of Table Grapes (European or Vinifera Type) 1 Definitions § 51.911 Container. Container... of grapes in packages containing 5 pounds or less, mean the master container in which the individual...

  11. 7 CFR 51.2083 - Clean.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Clean. 51.2083 Section 51.2083 Agriculture Regulations... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Almonds in the Shell Definitions § 51.2083 Clean. Clean means that the shell is...

  12. Coke battery with 51-m{sup 3} furnace chambers and lateral supply of mixed gas

    Energy Technology Data Exchange (ETDEWEB)

    V.I. Rudyka; N.Y. Chebotarev; O.N. Surenskii; V.V. Derevich [Giprokoks, the State Institute for the Design of Coke-Industry Enterprises, Kharkov (Ukraine)

    2009-07-15

    The basic approaches employed in the construction of coke battery 11A at OAO Magnitogorskii Metallurgicheskii Kombinat are outlined. This battery includes 51.0-m{sup 3} furnaces and a dust-free coke-supply system designed by Giprokoks with lateral gas supply; it is heated exclusively by low-calorific mixed gas consisting of blast-furnace gas with added coke-oven gas. The 82 furnaces in the coke battery are divided into two blocks of 41. The gross coke output of the battery (6% moisture content) is 1140000 t/yr.

  13. 7 CFR 51.1156 - Firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Firm. 51.1156 Section 51.1156 Agriculture Regulations... Standards for Grades of Florida Oranges and Tangelos Definitions § 51.1156 Firm. Firm as applied to common... oranges of the Mandarin group (Satsumas, King, Mandarin), “firm” means that the fruit is not extremely...

  14. 28 CFR 33.51 - Audit.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Audit. 33.51 Section 33.51 Judicial... Additional Requirements § 33.51 Audit. Pursuant to Office of Management and Budget Circular A-128 “Audits of State and Local Governments,” all grantees and subgrantees must provide for an independent audit of...

  15. 34 CFR 106.51 - Employment.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Employment. 106.51 Section 106.51 Education Regulations... Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 106.51 Employment. (a) General. (1) No person shall, on the basis of sex, be excluded from participation in, be...

  16. 7 CFR 51.912 - Export.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Export. 51.912 Section 51.912 Agriculture Regulations... Standards for Grades of Table Grapes (European or Vinifera Type) 1 Definitions § 51.912 Export. When designated as Export, grapes shall be packed with any of the customary protective materials such as cushions...

  17. 32 CFR 1605.51 - Area.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Area. 1605.51 Section 1605.51 National Defense... ORGANIZATION Local Boards § 1605.51 Area. (a) The Director of Selective Service shall divide each State into local board areas and establish local boards. There shall be at least one local board in each county...

  18. 36 CFR 5.1 - Advertisements.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Advertisements. 5.1 Section 5.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR COMMERCIAL AND PRIVATE OPERATIONS § 5.1 Advertisements. Commercial notices or advertisements shall not be displayed, posted, or distributed on federally owned o...

  19. 4 CFR 5.1 - Pay.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Pay. 5.1 Section 5.1 Accounts GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL SYSTEM COMPENSATION § 5.1 Pay. (a) Pay principles. Pay of the employees of GAO shall be fixed by the Comptroller General consistent with the principles that— (1) There be equal pay for work of...

  20. Accumulation and distribution patterns of trivalent 51Cr in rats

    International Nuclear Information System (INIS)

    Zimakov, I.E.; Sin'kov, V.I.; Zakharova, L.L.

    1986-01-01

    The effect of stable isotope of trivalent chromium on the behaviour of its radioactive isotope 54 Cr in the feed-animal food chain is studied. It is shown that the doses of stable chromium of 5 mg/kg and less practically exert no influence on the regularities of 51 Cr behaviour in the organism animals statistically the reliable effect on the Cr 51 level in separate organs and tissues of animals is noted at the doses of stable isotope carrier of 20 and 40 mg/kg. To establish the stable carrier effect f 1 and f 2 their values have been compared in case of 51 Cr single intake without carrier and with stable isotope carrier in the amount of 50 mg/kg. In the last case for kidneys the Ff 2 value decreased and became 0.04 whereas for the spleen practically remained the same

  1. On the Spatially Resolved Star Formation History in M51. II. X-Ray Binary Population Evolution

    Science.gov (United States)

    Lehmer, B. D.; Eufrasio, R. T.; Markwardt, L.; Zezas, A.; Basu-Zych, A.; Fragos, T.; Hornschemeier, A. E.; Ptak, A.; Tzanavaris, P.; Yukita, M.

    2017-12-01

    We present a new technique for empirically calibrating how the X-ray luminosity function (XLF) of X-ray binary (XRB) populations evolves following a star formation event. We first utilize detailed stellar population synthesis modeling of far-UV-to-far-IR photometry of the nearby face-on spiral galaxy M51 to construct maps of the star formation histories (SFHs) on subgalactic (≈400 pc) scales. Next, we use the ≈850 ks cumulative Chandra exposure of M51 to identify and isolate 2-7 keV detected point sources within the galaxy, and we use our SFH maps to recover the local properties of the stellar populations in which each X-ray source is located. We then divide the galaxy into various subregions based on their SFH properties (e.g., star formation rate (SFR) per stellar mass ({M}\\star ) and mass-weighted stellar age) and group the X-ray point sources according to the characteristics of the regions in which they are found. Finally, we construct and fit a parameterized XLF model that quantifies how the XLF shape and normalization evolves as a function of the XRB population age Our best-fit model indicates that the XRB XLF per unit stellar mass declines in normalization, by ˜3-3.5 dex, and steepens in slope from ≈10 Myr to ≈10 Gyr. We find that our technique recovers results from past studies of how XRB XLFs and XRB luminosity scaling relations vary with age and provides a self-consistent picture for how XRB XLFs evolve with age.

  2. Atmospheres of Two Super-Puffs: Transmission Spectra of Kepler 51b and Kepler 51d

    Science.gov (United States)

    Roberts, Jessica; Berta-Thompson, Zachory K.; Desert, Jean-Michel; Deck, Katherine; Fabrycky, Daniel; Fortney, Jonathan J.; Line, Michael R.; Lopez, Eric; Masuda, Kento; Morley, Caroline; Sanchis Ojeda, Roberto; Winn, Joshua N.

    2018-06-01

    The Kepler 51 system hosts three transiting, extremely low-mass, low-density exoplanets. These planets orbit a young G type star at periods of 45, 85 and 130 days, placing them outside of the regime for the inflated hot-Jupiters. Instead, the Kepler 51 planets are part of a rare class of exoplanets: the super-puffs. Models suggest these H/He-rich planets formed outside of the snow-line and migrated inwards, which might imply abundant water in their atmospheres. Because Kepler 51b and 51d have low surface gravities, they also have scale heights 10x larger than a typical hot-Jupiter, making them prime targets for atmospheric investigation. Kepler 51c, while also possessing a large scale height, only grazes its star during transit. We are also presented with a unique opportunity to study two super-puffs in very different temperature regimes around the same star. Therefore, we observed two transits each of both Kepler 51b and 51d with the Hubble Space Telescope’s Wide Field Camera 3 G141 grism spectroscopy. Using these data we created spectroscopic light curves that allow us to compute a transmission spectrum for each planet. We conclude that both planets have a flat transmission spectrum with a precision better than 0.6 scale heights between 1.1 and 1.7 microns. We also analyzed the transit timing variations of each planet by combining re-fitted Kepler mid-transit times with our measured HST times. From these additional timing points, we are able to better constrain the planetary masses and the dynamics of the system. With these updated masses and revisited stellar parameters, we determine precise measurements on the densities of these planets. We will present these results as well as discuss the implications for high altitude aerosols in both Kepler 51b and 51d.

  3. Euclidean geometry and its subgeometries

    CERN Document Server

    Specht, Edward John; Calkins, Keith G; Rhoads, Donald H

    2015-01-01

    In this monograph, the authors present a modern development of Euclidean geometry from independent axioms, using up-to-date language and providing detailed proofs. The axioms for incidence, betweenness, and plane separation are close to those of Hilbert. This is the only axiomatic treatment of Euclidean geometry that uses axioms not involving metric notions and that explores congruence and isometries by means of reflection mappings. The authors present thirteen axioms in sequence, proving as many theorems as possible at each stage and, in the process, building up subgeometries, most notably the Pasch and neutral geometries. Standard topics such as the congruence theorems for triangles, embedding the real numbers in a line, and coordinatization of the plane are included, as well as theorems of Pythagoras, Desargues, Pappas, Menelaus, and Ceva. The final chapter covers consistency and independence of axioms, as well as independence of definition properties. There are over 300 exercises; solutions to many of the...

  4. 34 CFR 5.1 - Act.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Act. 5.1 Section 5.1 Education Office of the Secretary...-10) Definitions § 5.1 Act. As used in this part, Act means section 552 of title 5, United States Code, as amended by Pub. L. 90-23, codifying the Act of July 4, 1966, sometimes referred to as the “Freedom...

  5. EnviroAtlas - New Bedford, MA - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  6. EnviroAtlas - Des Moines, IA - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. Forest is defined as Trees & Forest. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://enviroatlas.epa.gov/EnviroAtlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  7. EnviroAtlas - New York, NY - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. In this community, forest is defined as Trees & Forest. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  8. EnviroAtlas - Green Bay, WI - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets ).

  9. EnviroAtlas - Des Moines, IA - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. Vegetated cover is defined as Trees & Forest and Grass & Herbaceous. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://enviroatlas.epa.gov/EnviroAtlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  10. EnviroAtlas - Green Bay, WI - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area.This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets ).

  11. EnviroAtlas - New Bedford, MA - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  12. Melanin production by a yeast strain XJ5-1 of Aureobasidium melanogenum isolated from the Taklimakan desert and its role in the yeast survival in stress environments.

    Science.gov (United States)

    Jiang, Hong; Liu, Nan-Nan; Liu, Guang-Lei; Chi, Zhe; Wang, Jian-Ming; Zhang, Ly-Ly; Chi, Zhen-Ming

    2016-07-01

    The yeast strain XJ5-1 isolated from the Taklimakan desert soil was identified to be a strain of Aureobasdium melanogenum and could produce a large amount of melanin when it was grown in the PDA medium, but its melanin biosynthesis and expression of the PKS gene responsible for the melanin biosynthesis was significantly repressed in the presence of (NH4)2SO4. However, A. melanogenum P5 strain isolated from a mangrove ecosystem grown in both the presence and the absence of (NH4)2SO4 did not produce any melanin. The cell size of A. melanogenum XJ5-1 strain was much higher than that of A. melanogenum P5 strain. The melanized cells of the yeast strain XJ5-1 had higher tolerance to UV radiation, oxidation (200.0 mM H2O2), heat treatment (40 °C), salt shock (200.0 g/L NaCl), desiccation and strong acid hydrolysis (6.0 M HCl) at high temperature (80 °C) than the non-melanized cells of the same yeast strain XJ5-1. At the same time, the melanized cells of the yeast strain XJ5-1 also had higher tolerance to UV radiation, oxidation (200.0 mM H2O2), desiccation and strong acid hydrolysis (6.0 M HCl) at high temperature (80 °C) than A. melanogenum P5 strain, but had similar resistance to heat treatment (40 °C) and salt shock (200.0 g/L NaCl) compared to those of A. melanogenum P5 strain. All the results revealed that many characteristics of A. melanogenum XJ5-1 isolated from the Taklimakan desert soil was different from those of A. melanogenum P5 strain isolated from the mangrove ecosystem.

  13. Characterization of recombinant B. abortus strain RB51SOD towards understanding the uncorrelated innate and adaptive immune responses induced by RB51SOD compared to its parent vaccine strain RB51

    Directory of Open Access Journals (Sweden)

    Jianguo eZhu

    2011-11-01

    Full Text Available Brucella abortus is a Gram-negative, facultative intracellular pathogen for several mammals, including humans. Live attenuated B. abortus strain RB51 is currently the official vaccine used against bovine brucellosis in the United States and several other countries. Overexpression of protective B. abortus antigen Cu/Zn superoxide dismutase (SOD in a recombinant strain of RB51 (strain RB51SOD significantly increases its vaccine efficacy against virulent B. abortus challenge in a mouse model. An attempt has been made to better understand the mechanism of the enhanced protective immunity of RB51SOD compared to its parent strain RB51. We previously reported that RB51SOD stimulated enhanced Th1 immune response. In this study, we further found that T effector cells derived from RB51SOD-immunized mice exhibited significantly higher cytotoxic T lymphocyte (CTL activity than T effector cells derived from RB51-immunized mice against virulent B. abortus-infected target cells. Meanwhile, the macrophage responses to these two strains were also studied. Compared to RB51, RB51SOD cells had a lower survival rate in macrophages and induced lower levels of macrophage apoptosis and necrosis. The decreased survival of RB51SOD cells correlates with the higher sensitivity of RB51SOD, compared to RB51, to the bactericidal action of either Polymyxin B or sodium dodecyl sulfate (SDS. Furthermore, a physical damage to the outer membrane of RB51SOD was observed by electron microscopy. Possibly due to the physical damage, overexpressed Cu/Zn SOD in RB51SOD was found to be released into the bacterial cell culture medium. Therefore, the stronger adaptive immunity induced by RB51SOD did not correlate with the low level of innate immunity induced by RB51SOD compared to RB51. This unique and apparently contradictory profile is likely associated with the differences in outer membrane integrity and Cu/Zn SOD release.

  14. Glomerular filtration rate measured by 51Cr-EDTA clearance: evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis

    International Nuclear Information System (INIS)

    Chaves, Anna Alice Rolim; Buchpiguel, Carlos Alberto; Praxedes, Jose Nery; Bortolotto, Luiz Aparecido; Sapienza, Marcelo Tatit

    2010-01-01

    Introduction: renal artery stenosis can lead to renovascular hypertension; however, the detection of stenosis alone does not guarantee the presence of renovascular hypertension. Renovascular hypertension depends on activation of the renin-angiotensin system, which can be detected by functional tests such as captopril renal scintigraphy. A method that allows direct measurement of the baseline and post-captopril glomerular filtration rate using chromium-51 labeled ethylenediamine tetraacetic acid ( 51 Cr-EDTA) could add valuable information to the investigation of hypertensive patients with renal artery stenosis. The purposes of this study were to create a protocol to measure the baseline and post-captopril glomerular filtration rate using 51 Cr-EDTA, and to verify whether changes in the glomerular filtration rate permit differentiation between hypertensive patients with and without renal artery stenosis. Methods: this prospective study included 41 consecutive patients with poorly controlled severe hypertension. All patients had undergone a radiological investigation of renal artery stenosis within the month prior to their inclusion. The patients were divided into two groups: patients with (n=21) and without renal artery stenosis, (n=20). In vitro glomerular filtration rate analysis ( 51 Cr-EDTA) and 99m Tc-DMSA scintigraphy were performed before and after captopril administration in all patients. Results: the mean baseline glomerular filtration rate was 48.6±21.8 ml/kg/1.73 m 2 in the group with renal artery stenosis, which was significantly lower than the GFR of 65.1±28.7 ml/kg/1.73m 2 in the group without renal artery stenosis (p=0.04). Captopril induced a significant reduction of the glomerular filtration rate in the group with renal artery stenosis (to 32.6±14.8 ml/kg/1.73m 2 , p=0.001) and an insignificant change in the group without RAS (to 62.2±23.6 ml/kg/1.73m 2 , p=0.68). Scintigraphy with technetium-99m dimercapto-succinic acid (DMSA) did not show

  15. MPT-51/CpG DNA vaccine protects mice against Mycobacterium tuberculosis.

    Science.gov (United States)

    Silva, Bruna Daniella de Souza; da Silva, Ediane Batista; do Nascimento, Ivan Pereira; Dos Reis, Michelle Cristina Guerreiro; Kipnis, André; Junqueira-Kipnis, Ana Paula

    2009-07-16

    Tuberculosis (TB) is a severe infectious disease that kills approximately two million people worldwide every year. Because BCG protection is variable and does not protects adults, there is a great need for a new vaccine against TB that does not represent a risk for immunocompromised patients and that is also capable of protecting adult individuals. MPT-51 is a protein found in the genome of mycobacteria and binds to the fibronectin of the extracellular matrix, which may have a role in host tissue attachment and virulence. In order to test the usefulness of MPT-51 as a subunit vaccine, BALB/c were vaccinated and challenged with Mycobacterium tuberculosis. The infection of BALB/c with M. tuberculosis increased the number of IFN-gamma(+) T lymphocytes specific to MPT-51 in the spleen and lungs. Inoculation with rMPT-51/FIA and with rMPT-51/CpG DNA in non-infected BALB/c increased the amounts of IFN-gamma(+) T lymphocytes. Inoculation with rMPT-51/FIA also induced a humoral response specific to MPT-51. CFU counts of lung tissues done 60 days after infection showed a reduction of about 2 log in the bacteria load in the group of animals inoculated with rMPT-51/CpG DNA. These results make MPT-51 a valuable component to be further evaluated in the development of other subunit vaccines.

  16. Analytical study on abnormal change in time-variable gravity at Yichang seismostation before the M5.1 Badong earthquake

    Directory of Open Access Journals (Sweden)

    Wei Jin

    2014-02-01

    Full Text Available An M5.1 earthquake occurred in Badong County, only 66 km from the Three Gorges Dam, on December 16, 2013. The continuous gravity observation data obtained at Yichang seismostation nearest to the epicenter (96 km were analyzed, and it was found that the continuous gravity observation data obtained in this rainy season did not exhibit a characteristic of seasonal change in gravity identical to that in the past years, and thereafter the M5.1 Badong earthquake occurred. Numerical simulation revealed that the water storage and discharge of the Three Gorges reservoir generated seasonal change in gravity, and the changes in atmospheric pressure and gravity load were not the main sources of the seasonal change of continuous gravity observation data whether in respect of magnitude or phase and did not have obvious breaking change on annual variation before the earthquake. Through analysis of the seasonal change data observed on the same site including cavern temperature, rainfall data and global terrestrial water model (CPC simulated water load, it was thought that, in the observation room with cavern temperature change of only −0.11 °C/a at Yichang seismostation, the seasonal change of continuous gravity observation result mainly originated from the seasonal change in rainfall. In the case that the changes in rainfall and its water load did not have evident breaking change on annual variation law before the earthquake, if the M5.1 Badong earthquake was the cause of the breaking change on annual variation law in Yichang this time, then it was believed through analysis of crust expansion ratio that similar anomaly should occur at a crust expansion and compression intersection, no more than 100 km away from the epicenter.

  17. Physical, biochemical and genetic characterization of enterocin CE5-1 produced by Enterococcus faecium CE5-1 isolated from Thai indigenous chicken intestinal tract

    Directory of Open Access Journals (Sweden)

    Kraiyot Saelim

    2015-06-01

    Full Text Available Enterocin CE5-1 produced by Enterococcus faecium CE5-1 isolated from the chicken gastrointestinal tract was active in the wide range of pH 2-10 and temperature 30-100°C and sensitive to proteolytic enzymes and -amylase. It remained active after storage at -20°C for 2 months. Moreover, enterocin CE5-1 showed antibacterial activity against lactobacilli, bacilli, listeria, staphylococci and enterococci, especially antibiotic-resistant enterococci. In vitro study of enterocin CE5-1 decreased the population of Ent. faecalis VanB from 6.03 to 4.03 log CFU/ml. The lethal mode of action of enterocin CE5-1 appeared to be pore and filament formation in the cell wall. PCR sequencing analysis revealed the presence of two open reading frames (ORFs, containing enterocin CE5-1 (entCE5-1 and enterocin immunity (entI gene. Therefore, enterocin CE5-1 from Ent. faecium CE5-1 could possibly be used as an antimicrobial agent to control foodborne pathogen, spoilage bacteria and antibiotic-resistant enterococci in foods, feeds and the environments.

  18. Physical, biochemical and genetic characterization of enterocin CE5-1 produced by Enterococcus faecium CE5-1 isolated from Thai indigenous chicken intestinal tract

    OpenAIRE

    Kraiyot Saelim; Sireewan Kaewsuwan; Akio Tani; Suppasil Maneerat

    2015-01-01

    Enterocin CE5-1 produced by Enterococcus faecium CE5-1 isolated from the chicken gastrointestinal tract was active in the wide range of pH 2-10 and temperature 30-100°C and sensitive to proteolytic enzymes and -amylase. It remained active after storage at -20°C for 2 months. Moreover, enterocin CE5-1 showed antibacterial activity against lactobacilli, bacilli, listeria, staphylococci and enterococci, especially antibiotic-resistant enterococci. In vitro study of enterocin CE5-1 decr...

  19. A novel interation of nucleolin with Rad51

    International Nuclear Information System (INIS)

    De, Ananya; Donahue, Sarah L.; Tabah, Azah; Castro, Nancy E.; Mraz, Naomi; Cruise, Jennifer L.; Campbell, Colin

    2006-01-01

    Nucleolin associates with various DNA repair, recombination, and replication proteins, and possesses DNA helicase, strand annealing, and strand pairing activities. Examination of nuclear protein extracts from human somatic cells revealed that nucleolin and Rad51 co-immunoprecipitate. Furthermore, purified recombinant Rad51 associates with in vitro transcribed and translated nucleolin. Electroporation-mediated introduction of anti-nucleolin antibody resulted in a 10- to 20-fold reduction in intra-plasmid homologous recombination activity in human fibrosarcoma cells. Additionally, introduction of anti-nucleolin antibody sensitized cells to death induced by the topoisomerase II inhibitor, amsacrine. Introduction of anti-Rad51 antibody also reduced intra-plasmid homologous recombination activity and induced hypersensitivity to amsacrine-induced cell death. Co-introduction of anti-nucleolin and anti-Rad51 antibodies did not produce additive effects on homologous recombination or on cellular sensitivity to amsacrine. The association of the two proteins raises the intriguing possibility that nucleolin binding to Rad51 may function to regulate homologous recombinational repair of chromosomal DNA

  20. Glomerular filtration rate measured by {sup 51}Cr-EDTA clearance: evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis

    Energy Technology Data Exchange (ETDEWEB)

    Chaves, Anna Alice Rolim; Buchpiguel, Carlos Alberto; Praxedes, Jose Nery; Bortolotto, Luiz Aparecido; Sapienza, Marcelo Tatit, E-mail: annaalice100@yahoo.com.b [Universidade de Sao Paulo (USP), SP (Brazil). Faculdade de Medicina. Dept. de Neurologia

    2010-07-01

    Introduction: renal artery stenosis can lead to renovascular hypertension; however, the detection of stenosis alone does not guarantee the presence of renovascular hypertension. Renovascular hypertension depends on activation of the renin-angiotensin system, which can be detected by functional tests such as captopril renal scintigraphy. A method that allows direct measurement of the baseline and post-captopril glomerular filtration rate using chromium-51 labeled ethylenediamine tetraacetic acid ({sup 51}Cr-EDTA) could add valuable information to the investigation of hypertensive patients with renal artery stenosis. The purposes of this study were to create a protocol to measure the baseline and post-captopril glomerular filtration rate using {sup 51}Cr-EDTA, and to verify whether changes in the glomerular filtration rate permit differentiation between hypertensive patients with and without renal artery stenosis. Methods: this prospective study included 41 consecutive patients with poorly controlled severe hypertension. All patients had undergone a radiological investigation of renal artery stenosis within the month prior to their inclusion. The patients were divided into two groups: patients with (n=21) and without renal artery stenosis, (n=20). In vitro glomerular filtration rate analysis ({sup 51}Cr-EDTA) and {sup 99m}Tc-DMSA scintigraphy were performed before and after captopril administration in all patients. Results: the mean baseline glomerular filtration rate was 48.6+-21.8 ml/kg/1.73 m{sup 2} in the group with renal artery stenosis, which was significantly lower than the GFR of 65.1+-28.7 ml/kg/1.73m{sup 2} in the group without renal artery stenosis (p=0.04). Captopril induced a significant reduction of the glomerular filtration rate in the group with renal artery stenosis (to 32.6+-14.8 ml/kg/1.73m{sup 2}, p=0.001) and an insignificant change in the group without RAS (to 62.2+-23.6 ml/kg/1.73m{sup 2}, p=0.68). Scintigraphy with technetium-99m dimercapto

  1. 40 CFR 406.51 - Specialized definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Specialized definitions. 406.51 Section 406.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GRAIN MILLS POINT SOURCE CATEGORY Normal Rice Milling Subcategory § 406.51 Specialized definitions...

  2. 49 CFR 1242.65 - Other and casualties and insurance (accounts XX-51-99 and 50-51-00).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Other and casualties and insurance (accounts XX-51... RAILROADS 1 Operating Expenses-Transportation § 1242.65 Other and casualties and insurance (accounts XX-51... separation of administration (account XX-51-01). yard operations ...

  3. 24 CFR 51.203 - Safety standards.

    Science.gov (United States)

    2010-04-01

    ... Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.203 Safety standards. The following... facilities or areas shall not exceed 0.5 psi. (c) If a hazardous substance constitutes both a thermal...

  4. 7 CFR 51.1831 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.1831 Section 51.1831 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Florida Tangerines Definitions § 51.1831 Fairly firm. Fairly firm means that the...

  5. 7 CFR 51.774 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.774 Section 51.774 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Florida Grapefruit Definitions § 51.774 Fairly firm. Fairly firm means that the...

  6. 7 CFR 51.3204 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.3204 Section 51.3204 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Bermuda-Granex-Grano Type Onions Definitions § 51.3204 Fairly firm. Fairly firm...

  7. 7 CFR 51.1167 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.1167 Section 51.1167 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Florida Oranges and Tangelos Definitions § 51.1167 Fairly firm. Fairly firm as...

  8. 7 CFR 51.1904 - Maturity classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Maturity classification. 51.1904 Section 51.1904... STANDARDS) United States Consumer Standards for Fresh Tomatoes Size and Maturity Classification § 51.1904 Maturity classification. Tomatoes which are characteristically red when ripe, but are not overripe or soft...

  9. 14 CFR 33.51 - Operation test.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Operation test. 33.51 Section 33.51... STANDARDS: AIRCRAFT ENGINES Block Tests; Reciprocating Aircraft Engines § 33.51 Operation test. The operation test must include the testing found necessary by the Administrator to demonstrate backfire...

  10. 40 CFR 51.854 - Conformity analysis.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Conformity analysis. 51.854 Section 51... FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Determining Conformity of General Federal Actions to State or Federal Implementation Plans § 51.854 Conformity analysis. Link to an...

  11. 17 CFR 240.3a51-1 - Definition of “penny stock”.

    Science.gov (United States)

    2010-04-01

    ...), including hybrid products and derivative securities products, the national securities exchange or registered... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definition of âpenny stockâ. 240.3a51-1 Section 240.3a51-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

  12. 7 CFR 51.705 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.705 Section 51.705 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... § 51.705 Fairly firm. Fairly firm as applied to common oranges, means that the fruit may be slightly...

  13. 7 CFR 51.1012 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.1012 Section 51.1012 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Persian (Tahiti) Limes Definitions § 51.1012 Fairly firm. Fairly firm means that the fruit is...

  14. 7 CFR 51.2112 - Mixed varieties.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed varieties. 51.2112 Section 51.2112 Agriculture... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Shelled Almonds Mixed Varieties § 51.2112 Mixed varieties. Any lot of shelled...

  15. 7 CFR 51.1860 - Color classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Color classification. 51.1860 Section 51.1860... STANDARDS) United States Standards for Fresh Tomatoes 1 Color Classification § 51.1860 Color classification... illustrating the color classification requirements, as set forth in this section. This visual aid may be...

  16. 1 CFR 5.1 - Publication policy.

    Science.gov (United States)

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication... Federal Register shall publish a serial publication called the Federal Register to contain the following...

  17. 7 CFR 51.1240 - Paper ends.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Paper ends. 51.1240 Section 51.1240 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Cleaned Virginia Type Peanuts in the Shell Definitions § 51.1240 Paper ends. Paper ends means...

  18. 7 CFR 51.2295 - Half kernel.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Half kernel. 51.2295 Section 51.2295 Agriculture... Standards for Shelled English Walnuts (Juglans Regia) Definitions § 51.2295 Half kernel. Half kernel means the separated half of a kernel with not more than one-eighth broken off. ...

  19. 28 CFR 51.6 - Political subunits.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Political subunits. 51.6 Section 51.6 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE ADMINISTRATION OF SECTION 5 OF THE VOTING RIGHTS ACT OF 1965, AS AMENDED General Provisions § 51.6 Political subunits. All political...

  20. EnviroAtlas - New York, NY - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. In this community, vegetated cover is defined as Trees & Forest and Grass & Herbaceous. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets)

  1. 7 CFR 51.643 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.643 Section 51.643 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...) Definitions § 51.643 Fairly firm. Fairly firm means that the fruit may be slightly soft, but not bruised, and...

  2. 7 CFR 1218.51 - Financial statements.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Financial statements. 1218.51 Section 1218.51... § 1218.51 Financial statements. (a) As requested by the Secretary, the Council shall prepare and submit financial statements to the Secretary on a periodic basis. Each such financial statement shall include, but...

  3. 7 CFR 3550.51 - Program objectives.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Program objectives. 3550.51 Section 3550.51... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Section 502 Origination § 3550.51 Program objectives..., applicants are required to use section 502 funds in conjunction with funding or financing from other sources...

  4. 7 CFR 51.1903 - Size classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Size classification. 51.1903 Section 51.1903... STANDARDS) United States Consumer Standards for Fresh Tomatoes Size and Maturity Classification § 51.1903 Size classification. The following terms may be used for describing the size of the tomatoes in any lot...

  5. 41 CFR 51-10.102 - Application.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Application. 51-10.102 Section 51-10.102 Public Contracts and Property Management Other Provisions Relating to Public Contracts... WHO ARE BLIND OR SEVERELY DISABLED § 51-10.102 Application. This part applies to all programs or...

  6. 28 CFR 51.7 - Political parties.

    Science.gov (United States)

    2010-07-01

    ... THE VOTING RIGHTS ACT OF 1965, AS AMENDED General Provisions § 51.7 Political parties. Certain activities of political parties are subject to the preclearance requirement of section 5. A change affecting... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Political parties. 51.7 Section 51.7...

  7. A study of the 51Cr release assay system in micro-method

    International Nuclear Information System (INIS)

    Kiya, Katsuzo; Harada, Kiyoshi; Uozumi, Tohru; Toge, Tetsuya; Hattori, Takao.

    1981-01-01

    Conditions of 51 Cr release assay in microculture were investigated to measure the natural cytotoxic (NC) activity of mouse spleen cells. Malignant glioma (MG) cells of C57BL/6 mouse, induced by 20-methylcholanthrene, were labeled with Na 2 51 CrO 4 . Spleen cells collected from the same mouse strain were suspended in Eagle's MEM. Labeled MG cells and spleen cells were incubated for several hours in a CO 2 incubator. Then the activity of the supernatant was measured by an automatic gamma counter. The optimum conditions of 51 Cr release assay in micro-culture were, (1) number of the target cells: 5 x 10 3 / well (2) FCS concentration: 10% (3) E/T ratio: less than 100 : 1, 50 : 1 was possible (4) incubation time: 15 hours. The number of the target cells at labeling incubation was set to 2 x 10 6 /ml. Though the natural release of 51 Cr was not effected by the viability of the target cells, it was suggested that the NC activity was dependent on the viability of both cells, target and effector cells. (Tsunoda, M.)

  8. The young star cluster population of M51 with LEGUS - I. A comprehensive study of cluster formation and evolution

    Science.gov (United States)

    Messa, M.; Adamo, A.; Östlin, G.; Calzetti, D.; Grasha, K.; Grebel, E. K.; Shabani, F.; Chandar, R.; Dale, D. A.; Dobbs, C. L.; Elmegreen, B. G.; Fumagalli, M.; Gouliermis, D. A.; Kim, H.; Smith, L. J.; Thilker, D. A.; Tosi, M.; Ubeda, L.; Walterbos, R.; Whitmore, B. C.; Fedorenko, K.; Mahadevan, S.; Andrews, J. E.; Bright, S. N.; Cook, D. O.; Kahre, L.; Nair, P.; Pellerin, A.; Ryon, J. E.; Ahmad, S. D.; Beale, L. P.; Brown, K.; Clarkson, D. A.; Guidarelli, G. C.; Parziale, R.; Turner, J.; Weber, M.

    2018-01-01

    Recently acquired WFC3 UV (F275W and F336W) imaging mosaics under the Legacy Extragalactic UV Survey (LEGUS), combined with archival ACS data of M51, are used to study the young star cluster (YSC) population of this interacting system. Our newly extracted source catalogue contains 2834 cluster candidates, morphologically classified to be compact and uniform in colour, for which ages, masses and extinction are derived. In this first work we study the main properties of the YSC population of the whole galaxy, considering a mass-limited sample. Both luminosity and mass functions follow a power-law shape with slope -2, but at high luminosities and masses a dearth of sources is observed. The analysis of the mass function suggests that it is best fitted by a Schechter function with slope -2 and a truncation mass at 1.00 ± 0.12 × 105 M⊙. Through Monte Carlo simulations, we confirm this result and link the shape of the luminosity function to the presence of a truncation in the mass function. A mass limited age function analysis, between 10 and 200 Myr, suggests that the cluster population is undergoing only moderate disruption. We observe little variation in the shape of the mass function at masses above 1 × 104 M⊙ over this age range. The fraction of star formation happening in the form of bound clusters in M51 is ∼ 20 per cent in the age range 10-100 Myr and little variation is observed over the whole range from 1 to 200 Myr.

  9. The indolinone MAZ51 induces cell rounding and G2/M cell cycle arrest in glioma cells without the inhibition of VEGFR-3 phosphorylation: involvement of the RhoA and Akt/GSK3β signaling pathways.

    Directory of Open Access Journals (Sweden)

    Joo-Hee Park

    Full Text Available MAZ51 is an indolinone-based molecule originally synthesized as a selective inhibitor of vascular endothelial growth factor receptor (VEGFR-3 tyrosine kinase. This study shows that exposure of two glioma cell lines, rat C6 and human U251MG, to MAZ51 caused dramatic shape changes, including the retraction of cellular protrusions and cell rounding. These changes were caused by the clustering and aggregation of actin filaments and microtubules. MAZ51 also induced G2/M phase cell cycle arrest. This led to an inhibition of cellular proliferation, without triggering significant cell death. These alterations induced by MAZ51 occurred with similar dose- and time-dependent patterns. Treatment of glioma cells with MAZ51 resulted in increased levels of phosphorylated GSK3β through the activation of Akt, as well as increased levels of active RhoA. Interestingly, MAZ51 did not affect the morphology and cell cycle patterns of rat primary cortical astrocytes, suggesting it selectively targeted transformed cells. Immunoprecipitation-western blot analyses indicated that MAZ51 did not decrease, but rather increased, tyrosine phosphorylation of VEGFR-3. To confirm this unanticipated result, several additional experiments were conducted. Enhancing VEGFR-3 phosphorylation by treatment of glioma cells with VEGF-C affected neither cytoskeleton arrangements nor cell cycle patterns. In addition, the knockdown of VEGFR-3 in glioma cells did not cause morphological or cytoskeletal alterations. Furthermore, treatment of VEGFR-3-silenced cells with MAZ51 caused the same alterations of cell shape and cytoskeletal arrangements as that observed in control cells. These data indicate that MAZ51 causes cytoskeletal alterations and G2/M cell cycle arrest in glioma cells. These effects are mediated through phosphorylation of Akt/GSK3β and activation of RhoA. The anti-proliferative activity of MAZ51 does not require the inhibition of VEGFR-3 phosphorylation, suggesting that it is

  10. 47 CFR 51.503 - General pricing standard.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false General pricing standard. 51.503 Section 51.503... Pricing of Elements § 51.503 General pricing standard. (a) An incumbent LEC shall offer elements to... commission— (1) Pursuant to the forward-looking economic cost-based pricing methodology set forth in §§ 51...

  11. 7 CFR 51.1402 - Size classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Size classification. 51.1402 Section 51.1402... STANDARDS) United States Standards for Grades of Pecans in the Shell 1 Size Classification § 51.1402 Size classification. Size of pecans may be specified in connection with the grade in accordance with one of the...

  12. 7 CFR 51.17 - Official sampling.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Official sampling. 51.17 Section 51.17 Agriculture... Inspection Service § 51.17 Official sampling. Samples may be officially drawn by any duly authorized... time and place of the sampling and the brands or other identifying marks of the containers from which...

  13. 7 CFR 51.47 - Political activity.

    Science.gov (United States)

    2010-01-01

    ... Miscellaneous § 51.47 Political activity. All inspectors are forbidden, during the period of their respective appointments or while holding a valid inspectors' license to take an active part in political campaigns and a... 7 Agriculture 2 2010-01-01 2010-01-01 false Political activity. 51.47 Section 51.47 Agriculture...

  14. 7 CFR 51.2283 - Off color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Off color. 51.2283 Section 51.2283 Agriculture... Standards for Shelled English Walnuts (Juglans Regia) Color Requirements § 51.2283 Off color. The term “off color” is not a color classification, but shall be applied to any lot which fails to meet the...

  15. 14 CFR 294.51 - Presidential review.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Presidential review. 294.51 Section 294.51... REGULATIONS CANADIAN CHARTER AIR TAXI OPERATORS Cancellation of Registration and Presidential Review § 294.51 Presidential review. A Department order under § 294.50 (e), (g) or (i) shall be subject to stay or disapproval...

  16. 7 CFR 51.1441 - Half-kernel.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Half-kernel. 51.1441 Section 51.1441 Agriculture... Standards for Grades of Shelled Pecans Definitions § 51.1441 Half-kernel. Half-kernel means one of the separated halves of an entire pecan kernel with not more than one-eighth of its original volume missing...

  17. 49 CFR 1242.56 - Engine crews and train crews (accounts XX-51-56 and XX-51-57).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Engine crews and train crews (accounts XX-51-56 and XX-51-57). 1242.56 Section 1242.56 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Transportation § 1242.56 Engine crews and train crews (accounts XX-51-56 and...

  18. 28 CFR 345.51 - Inmate pay.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Inmate pay. 345.51 Section 345.51... (FPI) INMATE WORK PROGRAMS Inmate Pay and Benefits § 345.51 Inmate pay. (a) Grade levels. Inmate workers in FPI locations receive pay at five levels ranging from 5th grade pay (lowest) to 1st grade pay...

  19. The Gd14Ag51 structure type and its relation to some complex amalgam structures

    International Nuclear Information System (INIS)

    Tambornino, Frank; Sappl, Jonathan; Hoch, Constantin

    2015-01-01

    Highlights: • The Gd 14 Ag 51 structure type has been revisited on the basis of single crystal diffraction data. • Symmetry analysis from electron density and TEM shows the space group P6/m to be true. • Gd 14 Ag 51 shows good metallic behaviour. • Structure relations to alkali, alkaline-earth and rare-earth metal amalgams can be established. • Complexity values for the RE 14 Ag 51 structure family were calculated. - Abstract: A plethora of binary and ternary intermetallic compounds has been assigned to the Gd 14 Ag 51 structure type, crystallising in the hexagonal system (space group P6/m, a = 1264.30(18) pm, c = 933.58(11) pm for Gd 14 Ag 51 ). Starting in the late 1960s, much work has been invested in the structural elucidation of these crystal structures. However, reliable single crystal data are scarce, and most structure type assignments have been performed merely on the basis of powder data. We have redetermined four representatives of the binary RE 14 Ag 51 structure type (RE = Y, Ce, Gd, Tb) with modern high-precision single crystal X-ray methods. The assignment of the Gd 14 Ag 51 structure type to space group P6/m was additionally verified by careful analysis of high resolution transmission electron micrographs. We emphasise the close relation of the Gd 14 Ag 51 structure type to the structures of some recently described amalgams of similar composition focussing on disorder phenomena and structural complexity. Furthermore, we provide detailed information on synthesis as well as electrical and magnetic properties for Gd 14 Ag 51 , the parent compound of this structure family

  20. Non-Euclidean geometry

    CERN Document Server

    Kulczycki, Stefan

    2008-01-01

    This accessible approach features two varieties of proofs: stereometric and planimetric, as well as elementary proofs that employ only the simplest properties of the plane. A short history of geometry precedes a systematic exposition of the principles of non-Euclidean geometry.Starting with fundamental assumptions, the author examines the theorems of Hjelmslev, mapping a plane into a circle, the angle of parallelism and area of a polygon, regular polygons, straight lines and planes in space, and the horosphere. Further development of the theory covers hyperbolic functions, the geometry of suff

  1. 28 CFR 65.51 - Recordkeeping.

    Science.gov (United States)

    2010-07-01

    ... examination, to any books, documents, and records of recipients of Federal law enforcement assistance provided... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Recordkeeping. 65.51 Section 65.51 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) EMERGENCY FEDERAL LAW ENFORCEMENT ASSISTANCE...

  2. 'Scan GFR' as an alternative to 51Cr-EDTA clearance

    International Nuclear Information System (INIS)

    Osman, E.A.; Clarke, M.B.; Barrett, J.J.; Parsons, V.; Dulwich Hospital, London

    1989-01-01

    In this report 39 patients had their GFR assessed by 51 Cr-EDTA in a single shot-multiple sampling technique and also by measuring the quantitative renal uptake of 99m Tc-DTPA during a standard renal imaging test. The results showed a correlation coefficient of 0.96 between the two techniques. By using linear regression analysis the GFR was derived from the % renal uptake of DTPA in a further series of 24 patients in whom the 51 Cr-EDTA method was also employed. The two methods were compared and showed a correlation coefficient of 0.94 with a mean GFR difference of 7 ± 4.5 ml/min over a 51 Cr-EDTA range of 38-150 ml/min. (orig.) [de

  3. 7 CFR 51.1140 - General.

    Science.gov (United States)

    2010-01-01

    .... paradisi and C. grandis). Separate U.S. standards apply to tangerines. The standards for internal quality... 7 Agriculture 2 2010-01-01 2010-01-01 false General. 51.1140 Section 51.1140 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  4. 7 CFR 51.1560 - Damage.

    Science.gov (United States)

    2010-01-01

    ... of defects, which materially detracts from the edible or marketing quality, or the internal or... 7 Agriculture 2 2010-01-01 2010-01-01 false Damage. 51.1560 Section 51.1560 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  5. Factoring 51 and 85 with 8 qubits.

    Science.gov (United States)

    Geller, Michael R; Zhou, Zhongyuan

    2013-10-28

    We construct simplified quantum circuits for Shor's order-finding algorithm for composites N given by products of the Fermat primes 3, 5, 17, 257, and 65537. Such composites, including the previously studied case of 15, as well as 51, 85, 771, 1285, 4369, … have the simplifying property that the order of a modulo N for every base a coprime to N is a power of 2, significantly reducing the usual phase estimation precision requirement. Prime factorization of 51 and 85 can be demonstrated with only 8 qubits and a modular exponentiation circuit consisting of no more than four CNOT gates.

  6. Factoring 51 and 85 with 8 qubits

    Science.gov (United States)

    Geller, Michael R.; Zhou, Zhongyuan

    2013-10-01

    We construct simplified quantum circuits for Shor's order-finding algorithm for composites N given by products of the Fermat primes 3, 5, 17, 257, and 65537. Such composites, including the previously studied case of 15, as well as 51, 85, 771, 1285, 4369, … have the simplifying property that the order of a modulo N for every base a coprime to N is a power of 2, significantly reducing the usual phase estimation precision requirement. Prime factorization of 51 and 85 can be demonstrated with only 8 qubits and a modular exponentiation circuit consisting of no more than four CNOT gates.

  7. 7 CFR 906.51 - Reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Reports. 906.51 Section 906.51 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and..., pursuant to which the fruit was handled, together with the destination of each lot of fruit handled...

  8. 28 CFR 51.59 - Redistrictings.

    Science.gov (United States)

    2010-07-01

    ... extent to which the plan departs from objective redistricting criteria set by the submitting jurisdiction... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Redistrictings. 51.59 Section 51.59 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE ADMINISTRATION OF SECTION 5 OF...

  9. 51Cr-ethylenediaminetetraacetic acid absorption test

    International Nuclear Information System (INIS)

    Aabakken, L.

    1989-01-01

    The 51 Cr-ethylenediaminetetraacetic acid (EDTA) absorption test was evaluated in 83 healthy, male volunteers. Base-line 24 h excretion after peroral administration ranged from 0.88% to 7.96%, with a higher median absorption than reported by most authors (2.45%). However, the reproducibility and stability of the method and the reproducibility of the results were satisfactory. Urinary excretion after intraduodenal installation (n=18) was comparable to that seen after peroral test dose administration, indicating a limited significance of gastric 51 Cr-EDTA absorption under normal conditions. In 16 subjects a single intake of alcohol immediately before the test gave a modest and short-lasting increase in 51 Cr-EDTA absorption. No correlation was seen to body mass index, creatinine clearance, urinary volume, or small-bowel transit time, possibly reducing the number of confounding factors in the evaluation of absorption data. A small but significant negative correlation was, however, found to body surface area and age

  10. 7 CFR 51.632 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.632 Section 51.632 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards..., and Arizona) Definitions § 51.632 Similar varietal characteristics. Similar varietal characteristics...

  11. 7 CFR 51.694 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.694 Section 51.694 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards..., and Arizona) Definitions § 51.694 Similar varietal characteristics. Similar varietal characteristics...

  12. RAD51B in Familial Breast Cancer.

    Directory of Open Access Journals (Sweden)

    Liisa M Pelttari

    Full Text Available Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC that were genotyped on a custom chip (iCOGS. We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients and subsequently genotyped the mutation in additional breast cancer cases (n = 5259 and population controls (n = 3586 from Finland and Belarus. No significant association with breast cancer risk was seen in the meta-analysis of the Finnish datasets or in the large BCAC dataset. The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR: 1.15, 95% confidence interval (CI: 1.11-1.19, P = 8.88 x 10-16 and among familial cases (OR: 1.24, 95% CI: 1.16-1.32, P = 6.19 x 10-11, compared to the haplotype with the respective protective alleles. Our results suggest that loss-of-function mutations in RAD51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk.

  13. RAD51B in Familial Breast Cancer

    Science.gov (United States)

    Pelttari, Liisa M.; Khan, Sofia; Vuorela, Mikko; Kiiski, Johanna I.; Vilske, Sara; Nevanlinna, Viivi; Ranta, Salla; Schleutker, Johanna; Winqvist, Robert; Kallioniemi, Anne; Dörk, Thilo; Bogdanova, Natalia V.; Figueroa, Jonine; Pharoah, Paul D. P.; Schmidt, Marjanka K.; Dunning, Alison M.; García-Closas, Montserrat; Bolla, Manjeet K.; Dennis, Joe; Michailidou, Kyriaki; Wang, Qin; Hopper, John L.; Southey, Melissa C.; Rosenberg, Efraim H.; Fasching, Peter A.; Beckmann, Matthias W.; Peto, Julian; dos-Santos-Silva, Isabel; Sawyer, Elinor J.; Tomlinson, Ian; Burwinkel, Barbara; Surowy, Harald; Guénel, Pascal; Truong, Thérèse; Bojesen, Stig E.; Nordestgaard, Børge G.; Benitez, Javier; González-Neira, Anna; Neuhausen, Susan L.; Anton-Culver, Hoda; Brenner, Hermann; Arndt, Volker; Meindl, Alfons; Schmutzler, Rita K.; Brauch, Hiltrud; Brüning, Thomas; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; Hartikainen, Jaana M.; Chenevix-Trench, Georgia; Van Dyck, Laurien; Janssen, Hilde; Chang-Claude, Jenny; Rudolph, Anja; Radice, Paolo; Peterlongo, Paolo; Hallberg, Emily; Olson, Janet E.; Giles, Graham G.; Milne, Roger L.; Haiman, Christopher A.; Schumacher, Fredrick; Simard, Jacques; Dumont, Martine; Kristensen, Vessela; Borresen-Dale, Anne-Lise; Zheng, Wei; Beeghly-Fadiel, Alicia; Grip, Mervi; Andrulis, Irene L.; Glendon, Gord; Devilee, Peter; Seynaeve, Caroline; Hooning, Maartje J.; Collée, Margriet; Cox, Angela; Cross, Simon S.; Shah, Mitul; Luben, Robert N.; Hamann, Ute; Torres, Diana; Jakubowska, Anna; Lubinski, Jan; Couch, Fergus J.; Yannoukakos, Drakoulis; Orr, Nick; Swerdlow, Anthony; Darabi, Hatef; Li, Jingmei; Czene, Kamila; Hall, Per; Easton, Douglas F.; Mattson, Johanna; Blomqvist, Carl; Aittomäki, Kristiina; Nevanlinna, Heli

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC) that were genotyped on a custom chip (iCOGS). We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients and subsequently genotyped the mutation in additional breast cancer cases (n = 5259) and population controls (n = 3586) from Finland and Belarus. No significant association with breast cancer risk was seen in the meta-analysis of the Finnish datasets or in the large BCAC dataset. The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR): 1.15, 95% confidence interval (CI): 1.11–1.19, P = 8.88 x 10−16) and among familial cases (OR: 1.24, 95% CI: 1.16–1.32, P = 6.19 x 10−11), compared to the haplotype with the respective protective alleles. Our results suggest that loss-of-function mutations in RAD51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk. PMID:27149063

  14. Pir51, a Rad51-interacting protein with high expression in aggressive lymphoma, controls mitomycin C sensitivity and prevents chromosomal breaks

    Energy Technology Data Exchange (ETDEWEB)

    Henson, Sarah E. [Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Tsai, Shih-Chang [Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Malone, Cindy Sue [Department of Biology, California State University Northridge, Northridge, CA 91330 (United States); Soghomonian, Shahe V. [Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Ouyang, Yan [Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Wall, Randolph [Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Molecular Biology Institute and Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Marahrens, York [Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States) and Molecular Biology Institute and Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States)]. E-mail: YMarahrens@mednet.ucla.edu; Teitell, Michael A. [Molecular Biology Institute and Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States) and Department of Pathology and Laboratory Medicine, California NanoSystems Institute, and Institute for Stem Cell Biology and Medicine, University of California Los Angeles, Los Angeles, CA 90095 (United States)]. E-mail: mteitell@ucla.edu

    2006-10-10

    Pir51, a protein of unknown function that interacts with Rad51, was identified in a screen for genes that were highly expressed in aggressive mantle cell lymphoma (MCL) versus indolent small lymphocytic lymphoma (SLL) patient samples. We show that Pir51 is a nuclear protein expressed in a variety of cell types and that its expression is regulated during the cell cycle in a pattern nearly identical to Rad51. Also similar to Rad51, Pir51 levels did not change in response to a variety of DNA damaging agents. siRNA depletion of Pir51 did not reduce homologous recombination repair (HRR), but sensitized cells to mitomycin C (MMC)-induced DNA crosslinking and resulted in elevated levels of double-strand breaks (DSBs) in metaphase chromosome spreads and reduced colony formation. Therefore, Pir51 maintains genomic integrity and potentially connects the early response to DNA crosslinks, orchestrated by the ATR kinase and Fanconi Anemia (FA) proteins, to later stages of Rad51-dependent repair. Our results provide the first example of a Rad51-binding protein that influences DNA crosslink repair without affecting homologous recombination repair.

  15. Pir51, a Rad51-interacting protein with high expression in aggressive lymphoma, controls mitomycin C sensitivity and prevents chromosomal breaks

    International Nuclear Information System (INIS)

    Henson, Sarah E.; Tsai, Shih-Chang; Malone, Cindy Sue; Soghomonian, Shahe V.; Ouyang, Yan; Wall, Randolph; Marahrens, York; Teitell, Michael A.

    2006-01-01

    Pir51, a protein of unknown function that interacts with Rad51, was identified in a screen for genes that were highly expressed in aggressive mantle cell lymphoma (MCL) versus indolent small lymphocytic lymphoma (SLL) patient samples. We show that Pir51 is a nuclear protein expressed in a variety of cell types and that its expression is regulated during the cell cycle in a pattern nearly identical to Rad51. Also similar to Rad51, Pir51 levels did not change in response to a variety of DNA damaging agents. siRNA depletion of Pir51 did not reduce homologous recombination repair (HRR), but sensitized cells to mitomycin C (MMC)-induced DNA crosslinking and resulted in elevated levels of double-strand breaks (DSBs) in metaphase chromosome spreads and reduced colony formation. Therefore, Pir51 maintains genomic integrity and potentially connects the early response to DNA crosslinks, orchestrated by the ATR kinase and Fanconi Anemia (FA) proteins, to later stages of Rad51-dependent repair. Our results provide the first example of a Rad51-binding protein that influences DNA crosslink repair without affecting homologous recombination repair

  16. Biosafety of parenteral Brucella abortus RB51 vaccine in bison calves

    Science.gov (United States)

    Roffe, T.J.; Olsen, S.C.; Gidlewski, T.; Jensen, A.E.; Palmer, M.V.; Huber, R.

    1999-01-01

    Vaccination is considered among the primary management tools for reducing brucellosis prevalence in Greater Yellowstone Area (GYA) ungulates. Before their use, however, vaccine safety and efficacy must be demonstrated. Twenty-seven female bison (Bison bison) calves (approx 5 months old) were vaccinated with Brucella abortus Strain RB51 (1.5 x 1010 colony forming units [CFU], subcutaneously) as part of routine management. We assessed the persistence, pathology, shedding, and transmission associated with RB51 by serial necropsy, bacteriology, histopathology, and serology of 20 of these 27 vaccinated calves, and RB51 serology of 10 nonvaccinated, commingling adult females. With the exception of 1 calf, RB51 dot-blot titers at necropsy were <1:80. Strain RB51 was cultured from lymph nodes in 4 of 4 calves at 14 weeks postvaccination (PV), 4 of 4 calves at 18 weeks PV, 1 of 4 calves at 22 weeks PV, 3 of 4 at 26 weeks PV, and 0 of 4 calves at 30 weeks PV. No gross lesions were observed. Mild histologic changes occurred only in a few draining lymph nodes early in sampling. Adverse clinical effects were not observed in vaccinates. Swabs from nasopharynx, conjunctiva, rectum, and vagina were uniformly culture negative for RB51. Strain RB51 dot-blot assays of bison cows were negative at a 1:20 dilution at 26 weeks PV. Our results suggest that RB51 persists longer in bison calves than in domestic cattle and is systemically distributed within lymphatic tissues. However, bison apparently clear the RB51 vaccine strain without shedding, transmission, or significant adverse reactions.

  17. 29 CFR 1926.51 - Sanitation.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Sanitation. 1926.51 Section 1926.51 Labor Regulations... Sanitation. (a) Potable water. (1) An adequate supply of potable water shall be provided in all places of...; (iv) Combustion toilets. (4) The requirements of this paragraph (c) for sanitation facilities shall...

  18. Matrices and Graphs in Euclidean Geometry

    Czech Academy of Sciences Publication Activity Database

    Fiedler, Miroslav

    2005-01-01

    Roč. 14, - (2005), s. 51-58 E-ISSN 1081-3810 R&D Projects: GA AV ČR IAA1030302 Institutional research plan: CEZ:AV0Z10300504 Keywords : Euclidean space * Gram matrix * biorthogonal bases * simplex * interior angle * Steiner circumscribed ellipsoid * right simplex Subject RIV: BA - General Mathematics http://www.math.technion.ac.il/iic/ ela / ela -articles/14.html

  19. Half-life of 51Mn

    Science.gov (United States)

    Graves, Stephen A.; Ellison, Paul A.; Valdovinos, Hector F.; Barnhart, Todd E.; Nickles, Robert J.; Engle, Jonathan W.

    2017-07-01

    The half-life of 51Mn was measured by serial gamma spectrometry of the 511-keV annihilation photon following decay by β+ emission. Data were collected every 100 seconds for 100,000-230,000 seconds within each measurement (n =4 ). The 511-keV incidence rate was calculated from the 511-keV spectral peak area and count duration, corrected for detector dead time and radioactive decay. Least-squares regression analysis was used to determine the half-life of 51Mn while accounting for the presence of background contaminants, notably 55Co. The result was 45.59 ±0.07 min, which is the highest precision measurement to date and disagrees with the current Nuclear Data Sheets value by over 6 σ .

  20. Genome sequence of Stachybotrys chartarum Strain 51-11

    Science.gov (United States)

    Stachybotrys chartarum strain 51-11 genome was sequenced by shotgun sequencing utilizing Illumina Hiseq 2000 and PacBio long read technology. Since Stachybotrys chartarum has been implicated in health impacts within water-damaged buildings, any information extracted from the geno...

  1. Thermodynamic properties of 5-(1-adamantyl)tetrazole

    Energy Technology Data Exchange (ETDEWEB)

    Stepurko, Elena N.; Paulechka, Yauheni U.; Blokhin, Andrey V., E-mail: blokhin@bsu.by; Kabo, Gennady J.; Voitekhovich, Sergei V.; Lyakhov, Alexander S.; Kohut, Sviataslau V.; Kazarovets, Tatiana E.

    2014-09-20

    Highlights: • Heat capacity, enthalpy of formation, vapor pressure, and enthalpy of sublimation were measured for 5-(1-adamantyl)tetrazole. • Crystal structure of the compound was determined from the X-ray diffraction analysis. • Ideal-gas thermodynamic properties of 5-(1-adamantyl)tetrazole were calculated. - Abstract: Temperature dependence of the heat capacity of 5-(1-adamantyl)tetrazole was studied between (5 and 370) K in a vacuum adiabatic calorimeter. From obtained data the thermodynamic properties of the compound in the condensed state were evaluated over the range of (0–370) K. The crystal structure of 5-(1-adamantyl)tetrazole was determined from the X-ray diffraction analysis. The saturated vapor pressure for crystalline 5-(1-adamantyl)tetrazole in the temperature ranges from (394 to 419) K was measured by the Knudsen effusion method, and its enthalpy of sublimation was obtained using these results. The standard enthalpy of formation for crystalline 5-(1-adamantyl)tetrazole at 298.15 K was determined in a static bomb combustion calorimeter. From these data, the standard enthalpy of formation for gaseous 5-(1-adamantyl)tetrazole was evaluated. The enthalpy of formation calculated using quantum chemical methods is in an excellent agreement with the experimental value. The thermodynamic properties of 5-(1-adamantyl)tetrazole in the ideal-gas state were calculated in the temperature range from (0 to 1000) K. The calculated entropy of gaseous 5-(1-adamantyl)tetrazole is in a good agreement with the one obtained from the experimental data.

  2. Thermodynamic properties of 5-(1-adamantyl)tetrazole

    International Nuclear Information System (INIS)

    Stepurko, Elena N.; Paulechka, Yauheni U.; Blokhin, Andrey V.; Kabo, Gennady J.; Voitekhovich, Sergei V.; Lyakhov, Alexander S.; Kohut, Sviataslau V.; Kazarovets, Tatiana E.

    2014-01-01

    Highlights: • Heat capacity, enthalpy of formation, vapor pressure, and enthalpy of sublimation were measured for 5-(1-adamantyl)tetrazole. • Crystal structure of the compound was determined from the X-ray diffraction analysis. • Ideal-gas thermodynamic properties of 5-(1-adamantyl)tetrazole were calculated. - Abstract: Temperature dependence of the heat capacity of 5-(1-adamantyl)tetrazole was studied between (5 and 370) K in a vacuum adiabatic calorimeter. From obtained data the thermodynamic properties of the compound in the condensed state were evaluated over the range of (0–370) K. The crystal structure of 5-(1-adamantyl)tetrazole was determined from the X-ray diffraction analysis. The saturated vapor pressure for crystalline 5-(1-adamantyl)tetrazole in the temperature ranges from (394 to 419) K was measured by the Knudsen effusion method, and its enthalpy of sublimation was obtained using these results. The standard enthalpy of formation for crystalline 5-(1-adamantyl)tetrazole at 298.15 K was determined in a static bomb combustion calorimeter. From these data, the standard enthalpy of formation for gaseous 5-(1-adamantyl)tetrazole was evaluated. The enthalpy of formation calculated using quantum chemical methods is in an excellent agreement with the experimental value. The thermodynamic properties of 5-(1-adamantyl)tetrazole in the ideal-gas state were calculated in the temperature range from (0 to 1000) K. The calculated entropy of gaseous 5-(1-adamantyl)tetrazole is in a good agreement with the one obtained from the experimental data

  3. 47 CFR 51.607 - Wholesale pricing standard.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Wholesale pricing standard. 51.607 Section 51.607 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Resale § 51.607 Wholesale pricing standard. The wholesale rate that an incumbent LEC may charge...

  4. Virial theorem and hypervirial theorem in a spherical geometry

    International Nuclear Information System (INIS)

    Li Yan; Chen Jingling; Zhang Fulin

    2011-01-01

    The virial theorem in the one- and two-dimensional spherical geometry are presented in both classical and quantum mechanics. Choosing a special class of hypervirial operators, the quantum hypervirial relations in the spherical spaces are obtained. With the aid of the Hellmann-Feynman theorem, these relations can be used to formulate a perturbation theorem without wavefunctions, corresponding to the hypervirial-Hellmann-Feynman theorem perturbation theorem of Euclidean geometry. The one-dimensional harmonic oscillator and two-dimensional Coulomb system in the spherical spaces are given as two sample examples to illustrate the perturbation method. (paper)

  5. 7 CFR 51.567 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.567 Section 51... STANDARDS) United States Standards for Celery Definitions § 51.567 Similar varietal characteristics. Similar varietal characteristics means that the stalks in any package have the same general appearance and...

  6. 49 CFR 230.51 - Number and location.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Number and location. 230.51 Section 230.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Water Glasses and Gauge Cocks § 230.51 Number and location. Every boiler shall be equipped with at least...

  7. 7 CFR 948.51 - Colorado Potato Committee.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Colorado Potato Committee. 948.51 Section 948.51... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN COLORADO Order Regulating Handling Committees § 948.51 Colorado Potato Committee. The Colorado Potato Committee...

  8. The effect of hafnium content on the transformation temperatures of Ni49Ti51-xHfx shape memory alloys

    International Nuclear Information System (INIS)

    Angst, D.R.; Thoma, P.E.; Kao, M.Y.

    1995-01-01

    Ternary alloys of NiTiHf, having higher transformation temperatures than binary NiTi shape memory alloys, have been produced and analyzed. Beginning with a base composition of Ni 49 Ti 51 , Hf was substituted for Ti up to 30 atomic percent. Differential scanning calorimetry was used to determine the transformation temperatures of the as-cast alloys. The peak martensite temperature of the Ni 49 Ti 51 alloy was 69 C and increased to 525 C for the Ni 49 Ti 21 Hf 30 alloy. The peak austenite temperature of the Ni 49 Ti 51 alloy was 114 C and increased to 622 C for the Ni 49 Ti 21 Hf 30 alloy. An apparent minimum in the peak transformation temperatures occurred between 0 and 3 atomic percent Hf. Preliminary experiments were also conducted to determine the effect of thermomechanical processing on the shape memory properties of the Ni 49 Ti 41 Hf 10 . Data are presented on the effect of cold work and heat treatment on the transformation temperatures of this alloy. (orig.)

  9. FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

    Science.gov (United States)

    Sato, Koichi; Shimomuki, Mayo; Katsuki, Yoko; Takahashi, Daisuke; Kobayashi, Wataru; Ishiai, Masamichi; Miyoshi, Hiroyuki; Takata, Minoru; Kurumizaka, Hitoshi

    2016-01-01

    The FANCI-FANCD2 (I-D) complex is considered to work with RAD51 to protect the damaged DNA in the stalled replication fork. However, the means by which this DNA protection is accomplished have remained elusive. In the present study, we found that the I-D complex directly binds to RAD51, and stabilizes the RAD51-DNA filament. Unexpectedly, the DNA binding activity of FANCI, but not FANCD2, is explicitly required for the I-D complex-mediated RAD51-DNA filament stabilization. The RAD51 filament stabilized by the I-D complex actually protects the DNA end from nucleolytic degradation by an FA-associated nuclease, FAN1. This DNA end protection is not observed with the RAD51 mutant from FANCR patient cells. These results clearly answer the currently enigmatic question of how RAD51 functions with the I-D complex to prevent genomic instability at the stalled replication fork. PMID:27694619

  10. 41 CFR 109-27.102-51 - Policy.

    Science.gov (United States)

    2010-07-01

    ...-INVENTORY MANAGEMENT 27.1-Stock Replenishment § 109-27.102-51 Policy. Systems contracting for supply... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Policy. 109-27.102-51 Section 109-27.102-51 Public Contracts and Property Management Federal Property Management Regulations...

  11. 28 CFR 51.3 - Delegation of authority.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Delegation of authority. 51.3 Section 51.3 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE ADMINISTRATION OF SECTION 5 OF THE VOTING RIGHTS ACT OF 1965, AS AMENDED General Provisions § 51.3 Delegation of authority...

  12. 7 CFR 51.56 - Buildings and structures.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Buildings and structures. 51.56 Section 51.56... § 51.56 Buildings and structures. The packing plant buildings shall be properly constructed and... be sufficient light consistent with the use to which the particular portion of the building is...

  13. 7 CFR 51.2278 - U.S. Commercial.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial. 51.2278 Section 51.2278 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Shelled English Walnuts (Juglans Regia) Grades § 51.2278 U.S. Commercial. “U.S. Commercial...

  14. 7 CFR 981.51 - Requirements for reserve.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Requirements for reserve. 981.51 Section 981.51... Regulating Handling Volume Regulation § 981.51 Requirements for reserve. Each handler may satisfy his reserve... include grade requirements for reserve almonds delivered to human consumption outlets. [41 FR 26853, June...

  15. Correlation of RAD51 and radiosensitization of methotrexate

    International Nuclear Information System (INIS)

    Du Liqing; Bai Jianqiang; Liu Qiang; Wang Yan; Zhao Peng; Chen Fenghua; Wang Hong; Fan Feiyue

    2012-01-01

    Objective: To evaluate the correlation between homologous recombination repair protein RAD51 and methotrexate-enhanced radiosensitivity. Methods: Western blot and RT-PCR assays were used to detect RAD51 expression in HOS osteosarcoma cells exposed to γ-ray irradiation alone and in combination with methotrexate. Colony formation assay was used to test the survival fraction of HOS cells exposed to γ-rays and methotrexate. Results: Methotrexate inhibited both protein and RNA expressions of RAD51, and the combination of radiation and methotrexate enhanced the inhibition of RAD51 expression. Moreover, transfection of cells with RAD51 gene decreased cellular sensitivity to methotrexate and γ-rays. The sensitizer enhancement ratios after irradiation in combination with methotrexate were 1.51 and 0.99, respectively. Methotrexate was a preferred radiosensitizer to HOS cell. Conclusions: RAD51 might be involved in the methotrexate-enhanced radiosensitivity. (authors)

  16. 42 CFR 447.51 - Requirements and options.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Requirements and options. 447.51 Section 447.51 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES..., Premium Or Similar Cost Sharing Charge § 447.51 Requirements and options. (a) The plan must provide that...

  17. 32 CFR 536.51 - Collateral source rule.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Collateral source rule. 536.51 Section 536.51... AGAINST THE UNITED STATES Investigation and Processing of Claims § 536.51 Collateral source rule. Where permitted by applicable state or maritime law, damages recovered from collateral sources are payable under...

  18. 7 CFR 51.1578 - Off-Grade potatoes.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Off-Grade potatoes. 51.1578 Section 51.1578... STANDARDS) United States Consumer Standards for Potatoes Off-Grade § 51.1578 Off-Grade potatoes. Potatoes which fail to meet the requirements of any of the foregoing grades shall be Off-Grade potatoes...

  19. 7 CFR 51.2561 - Average moisture content.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Average moisture content. 51.2561 Section 51.2561... STANDARDS) United States Standards for Grades of Shelled Pistachio Nuts § 51.2561 Average moisture content. (a) Determining average moisture content of the lot is not a requirement of the grades, except when...

  20. 7 CFR 51.2647 - U.S. Commercial.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial. 51.2647 Section 51.2647 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades for Sweet Cherries 1 Grades § 51.2647 U.S. Commercial. “U.S. Commercial” consists of...

  1. 7 CFR 51.1542 - U.S. Commercial.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial. 51.1542 Section 51.1542 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Standards for Grades of Potatoes 1 Grades § 51.1542 U.S. Commercial. “U.S. Commercial” consists of potatoes...

  2. 42 CFR 51c.112 - Grantee accountability.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Grantee accountability. 51c.112 Section 51c.112 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR COMMUNITY HEALTH SERVICES General Provisions § 51c.112 Grantee accountability. (a) Accounting for grant award...

  3. 10 CFR 51.3 - Resolution of conflict.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Resolution of conflict. 51.3 Section 51.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS § 51.3 Resolution of conflict. In any conflict between a general rule in subpart A of...

  4. 7 CFR 51.1141 - U.S. Fancy.

    Science.gov (United States)

    2010-01-01

    ... tolerances see § 51.1151. (f) Internal quality: Lots meeting the internal requirements for “U.S. Grade AA... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Fancy. 51.1141 Section 51.1141 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  5. 42 CFR 51.26 - Conflicts of interest.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Conflicts of interest. 51.26 Section 51.26 Public... Priorities § 51.26 Conflicts of interest. The P&A system must develop appropriate policies and procedures to avoid actual or apparent conflict of interest involving clients, employees, contractors and...

  6. 47 CFR 76.51 - Major television markets.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Major television markets. 76.51 Section 76.51... CABLE TELEVISION SERVICE Carriage of Television Broadcast Signals § 76.51 Major television markets. For purposes of the cable television rules, the following is a list of the major television markets and their...

  7. 2018-04-29T16:13:51Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    article/44895 2018-04-29T16:13:51Z gjpas:ART Anthropometric Comparison Of Cephalic Indices Between The Urhobo And Itsekiri Ethnic Groups Of Nigeria Oladipo, GS Paul, CW Cephalic index, ethnic groups and anthropology. Cephalic index ...

  8. EnviroAtlas - Minneapolis/St. Paul, MN - 51m Riparian Buffer Forest Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. In this community, forest is defined as Trees and Forest and Woody Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  9. EnviroAtlas - Minneapolis/St. Paul, MN - 51m Riparian Buffer Vegetated Cover

    Science.gov (United States)

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. In this community, vegetated cover is defined as Trees and Forest, Grass and Herbaceous, Woody Wetlands, and Emergent Wetlands. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the EnviroAtlas community area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  10. 7 CFR 51.2277 - U.S. No. 1.

    Science.gov (United States)

    2010-01-01

    ..., decay, rancidity, and free from damage caused by shriveling, mold, discoloration of the meat or other means. (See § 51.2280.) (a) Color shall be specified in connection with this grade in terms of one of the color classifications. (See §§ 51.2276, 51.2281 and 51.2282.) (b) Size shall be specified in...

  11. 7 CFR 51.1011 - Good green color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Good green color. 51.1011 Section 51.1011 Agriculture... Standards for Persian (Tahiti) Limes Definitions § 51.1011 Good green color. Good green color means that the skin of the lime is of a good green color characteristic of the Persian variety. ...

  12. 7 CFR 51.2282 - Tolerances for color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Tolerances for color. 51.2282 Section 51.2282... STANDARDS) United States Standards for Shelled English Walnuts (Juglans Regia) Color Requirements § 51.2282 Tolerances for color. (a) All percentages shall be calculated on the basis of weight. (b) In order to allow...

  13. 41 CFR 51-6.14 - Replacement services.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Replacement services. 51-6.14 Section 51-6.14 Public Contracts and Property Management Other Provisions Relating to Public... § 51-6.14 Replacement services. If a service is on the Procurement List to meet the needs of a...

  14. 32 CFR 935.51 - Motor vehicle violations.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Motor vehicle violations. 935.51 Section 935.51... REGULATIONS WAKE ISLAND CODE Penalties § 935.51 Motor vehicle violations. Whoever is found guilty of a... than 30 days, or suspension or revocation of his motor vehicle operator's permit, or any combination or...

  15. 39 CFR 5.1 - Establishment and appointment.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment and appointment. 5.1 Section 5.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE COMMITTEES (ARTICLE V) § 5.1 Establishment and appointment. From time to time the Board may establish by resolution...

  16. 12 CFR 1703.51 - Service of process.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Service of process. 1703.51 Section 1703.51... OFHEO § 1703.51 Service of process. (a) Except as otherwise provided by OFHEO regulations, the Federal.... (b) Service of process upon the General Counsel may be effected by personally delivering a copy of...

  17. 39 CFR 777.51 - Acceptance of donations.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Acceptance of donations. 777.51 Section 777.51... ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent a person from making a gift or donation of real property or any part thereof, or any interest therein, or...

  18. 7 CFR 51.1403 - Kernel color classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Kernel color classification. 51.1403 Section 51.1403... STANDARDS) United States Standards for Grades of Pecans in the Shell 1 Kernel Color Classification § 51.1403 Kernel color classification. (a) The skin color of pecan kernels may be described in terms of the color...

  19. A RING/DISK/OUTFLOW SYSTEM ASSOCIATED WITH W51 NORTH: A VERY MASSIVE STAR IN THE MAKING

    International Nuclear Information System (INIS)

    Zapata, Luis A.; Schilke, Peter; Menten, Karl; Ho, Paul T. P.; Rodriguez, Luis F.; Palau, Aina; Garrod, Robin T.

    2009-01-01

    Sensitive and high angular resolution (∼0.''4) SO 2 [22 2,20 → 22 1,21 ] and SiO[5 → 4] line and 1.3 and 7 mm continuum observations made with the Submillimeter Array (SMA) and the Very Large Array (VLA) toward the young massive cluster W51 IRS2 are presented. We report the presence of a large (of about 3000 AU) and massive (40 M sun ) dusty circumstellar disk and a hot gas molecular ring around a high-mass protostar or a compact small stellar system associated with W51 North. The simultaneous observations of the silicon monoxide molecule, an outflow gas tracer, further revealed a massive (200 M sun ) and collimated (∼14 0 ) outflow nearly perpendicular to the dusty and molecular structures suggesting thus the presence of a single very massive protostar with a bolometric luminosity on the order of 10 5 L sun . A molecular hybrid local thermodynamic equilibrium model of a Keplerian and infalling disk with an inner cavity and a central stellar mass of more than 60 M sun agrees well with the SO 2 [22 2,20 → 22 1,21 ] line observations. Finally, these results suggest that mechanisms, such as mergers of low- and intermediate-mass stars, might not be necessary for forming very massive stars.

  20. Function of Rad51 paralogs in eukaryotic homologous recombinational repair

    International Nuclear Information System (INIS)

    Liu, N.; Skowronek, K.

    2003-01-01

    Full text: Homologous recombinational repair (HRR) is an important mechanism for maintaining genetic integrity and cancer prevention by accurately repair of DNA double strand breaks induced by environmental insults or occurred in DNA replication. A critical step in HRR is the polymerization of Rad51 on single stranded DNA to form nuclear protein filaments, the later conduct DNA strand paring and exchange between homologous strands. A number of proteins, including replication protein A (RPA), Rad52 and Rad51 paralogs, are suggested to modulate or facilitate the process of Rad51 filament formation. Five Rad51 paralogs, namely XRCC2, XRCC3, Rad51B, Rad51C and Rad51D have been identified in eucaryotic cells. These proteins show distant protein sequence identity to Rad51, to yeast Rad51 paralogs (Rad55 and Rad57) and to each other. Hamster or chicken mutants of Rad51 paralogs exhibit hypersensitivity to a variety of DNA damaging agents, especially cross-linking agents, and are defective in assembly of Rad51 onto HRR site after DNA damage. Recent data from our and other labs showed that Rad51 paralogs constitute two distinct complexes in cell extracts, one contains XRCC2, Rad51B, Rad51C and Rad51D, and the other contains Rad51C and XRCC3. Rad51C is involved in both complexes. Our results also showed that XRCC3-Rad51C complex interacts with Rad51 in vivo. Furthermore, overexpression of Rad52 can partially suppress the hypersensitivity of XRCC2 mutant irs1 to ionizing radiation and corrected the defects in Rad51 focus formation. These results suggest that XRCC2 and other Rad51 paralogs play a mediator function to Rad51 in the early stage of HRR

  1. 42 CFR 71.51 - Dogs and cats.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Dogs and cats. 71.51 Section 71.51 Public Health... QUARANTINE Importations § 71.51 Dogs and cats. (a) Definitions. As used in this section the term: Cat means all domestic cats. Confinement means restriction of a dog or cat to a building or other enclosure at a...

  2. Saksa asjalikkus ja kord 51. Mannheimi filmifesstivalil / Mart Kivastik

    Index Scriptorium Estoniae

    Kivastik, Mart, 1963-

    2002-01-01

    Mannheimi-Heidelbergi 51. filmifestival Saksamaal. Lähemalt kolmest mängufilmist rootslaste "Tokyo müra" ("Tokyo Noise") : režissöörid Kristian Petri, Jan Röed ja Johan Söderberg, ameeriklaste "Sitikas" ("Bug") : režissöör Matt Manfred ning hiinlaste "Kodutee" ("Wo de fu qin mu qin") : režissöör Zhang Yimou

  3. 7 CFR 1206.51 - Independent evaluation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Independent evaluation. 1206.51 Section 1206.51 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... INFORMATION Mango Promotion, Research, and Information Order Definitions Promotion, Research, and Information...

  4. 7 CFR 51.3741 - U.S. Commercial.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial. 51.3741 Section 51.3741 Agriculture... Standards for Grades of Honey Dew and Honey Ball Type Melons Grades § 51.3741 U.S. Commercial. “U.S. Commercial” consists of honey dew or honey ball type melons which meet the requirements of U.S. No. 1 grade...

  5. Rad51C deficiency destabilizes XRCC3, impairs recombination and radiosensitizes S/G2-phase cells

    Energy Technology Data Exchange (ETDEWEB)

    Lio, Yi-Ching; Schild, David; Brenneman, Mark A.; Redpath, J. Leslie; Chen, David J.

    2004-05-01

    The highly conserved Rad51 protein plays an essential role in repairing DNA damage through homologous recombination. In vertebrates, five Rad51 paralogs (Rad51B, Rad51C, Rad51D, XRCC2, XRCC3) are expressed in mitotically growing cells, and are thought to play mediating roles in homologous recombination, though their precise functions remain unclear. Here we report the use of RNA interference to deplete expression of Rad51C protein in human HT1080 and HeLa cells. In HT1080 cells, depletion of Rad51C by small interfering RNA caused a significant reduction of frequency in homologous recombination. The level of XRCC3 protein was also sharply reduced in Rad51C-depleted HeLa cells, suggesting that XRCC3 is dependent for its stability upon heterodimerization with Rad51C. In addition, Rad51C-depleted HeLa cells showed hypersensitivity to the DNA cross-linking agent mitomycin C, and moderately increased sensitivity to ionizing radiation. Importantly, the radiosensitivity of Rad51C-deficient HeLa cells was evident in S and G{sub 2}/M phases of the cell cycle but not in G{sub 1} phase. Together, these results provide direct cellular evidence for the importance of human Rad51C in homologous recombinational repair.

  6. Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy.

    Directory of Open Access Journals (Sweden)

    Eric K Hoobler

    Full Text Available We report the discovery of a novel dual inhibitor targeting fungal sterol 14α-demethylase (CYP51 or Erg11 and human 5-lipoxygenase (5-LOX with improved potency against 5-LOX due to its reduction of the iron center by its phenylenediamine core. A series of potent 5-LOX inhibitors containing a phenylenediamine core, were synthesized that exhibit nanomolar potency and >30-fold selectivity against the LOX paralogs, platelet-type 12-human lipoxygenase, reticulocyte 15-human lipoxygenase type-1, and epithelial 15-human lipoxygenase type-2, and >100-fold selectivity against ovine cyclooxygenase-1 and human cyclooxygnease-2. The phenylenediamine core was then translated into the structure of ketoconazole, a highly effective anti-fungal medication for seborrheic dermatitis, to generate a novel compound, ketaminazole. Ketaminazole was found to be a potent dual inhibitor against human 5-LOX (IC50 = 700 nM and CYP51 (IC50 = 43 nM in vitro. It was tested in whole blood and found to down-regulate LTB4 synthesis, displaying 45% inhibition at 10 µM. In addition, ketaminazole selectively inhibited yeast CYP51 relative to human CYP51 by 17-fold, which is greater selectivity than that of ketoconazole and could confer a therapeutic advantage. This novel dual anti-fungal/anti-inflammatory inhibitor could potentially have therapeutic uses against fungal infections that have an anti-inflammatory component.

  7. 40 CFR 439.51 - Special definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Special definitions. 439.51 Section 439.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND... purpose of this subpart, product means products or services resulting from research and product...

  8. 40 CFR 407.51 - Specialized definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Specialized definitions. 407.51 Section 407.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS CANNED AND PRESERVED FRUITS AND VEGETABLES PROCESSING POINT SOURCE CATEGORY Dehydrated Potato...

  9. Bicarbonate catalysis of exchange synthesis of [51Cr]Cr(III)-EDTA and other chromium complexes

    International Nuclear Information System (INIS)

    Aronson, F.L.; Strashun, A.M.; Lopez, C.; Steigman, J.

    1993-01-01

    Exchange syntheses of trivalent chromium complexes often require heating, thus limiting tagging of heat-sensitive biological compounds with 51 Cr. Bicarbonate at pH 6, accelerates the formation of mM Cr-EDTA. Accordingly, room temperature catalysis with [ 51 Cr]Cr(III) at 10 -7 -10 -8 M was investigated. Complexes were successfully formed with EDTA and iminodiacetic acid (electrophoretic analysis) and acetylacetone and tropolone (analyzed by chloroform extraction). The formation of these complexes normally requires extensive heating. (author)

  10. 7 CFR 51.576 - Mixed blanch.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed blanch. 51.576 Section 51.576 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946...

  11. 7 CFR 51.1997 - Similar type.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar type. 51.1997 Section 51.1997 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946...

  12. 40 CFR 51.359 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...

  13. Investigation on transition behavior and electrical properties of (K0.5Na0.51-xLixNb0.84Ta0.1Sb0.06O3 around polymorphic phase transition region

    Directory of Open Access Journals (Sweden)

    Chen Zhu

    2014-01-01

    Full Text Available (K0.5Na0.51-xLixNb0.84Ta0.1Sb0.06O3 (KNLNTS lead free ceramics with different Li concentration were fabricated by conventional solid-state reaction method. By increasing Li ions in KNLNTS, the grains grow up and the crystal structure changes from orthorhombic to tetragonal. When 0.03 ≤ x ≤ 0.05, the ceramics structure lays in PPT region. Polarization versus electric field (P-E hysteresis loops at room temperature show good ferroelectric properties and the remnant polarization decreases by increasing Li content while coercive electric keeps almost unchanged. In PPT region, taking x = 0.04 as an example, the sample shows excellent dielectric properties: the dielectric constant is 1159 and loss tangent is 0.04, while the piezoelectric constant d33 is 245 pC/N and kp is 0.44 at room temperature, it is promising for (K0.5Na0.51-xLixNb0.84Ta0.1Sb0.06O3 with 4 at. % Li to substitute PZT.

  14. Geometric Transformations in Engineering Geometry

    Directory of Open Access Journals (Sweden)

    I. F. Borovikov

    2015-01-01

    Full Text Available Recently, for business purposes, in view of current trends and world experience in training engineers, research and faculty staff there has been a need to transform traditional courses of descriptive geometry into the course of engineering geometry in which the geometrical transformations have to become its main section. On the basis of critical analysis the paper gives suggestions to improve a presentation technique of this section both in the classroom and in academic literature, extend an application scope of geometrical transformations to solve the position and metric tasks and simulation of surfaces, as well as to design complex engineering configurations, which meet a number of pre-specified conditions.The article offers to make a number of considerable amendments to the terms and definitions used in the existing courses of descriptive geometry. It draws some conclusions and makes the appropriate proposals on feasibility of coordination in teaching the movement transformation in the courses of analytical and descriptive geometry. This will provide interdisciplinary team teaching and allow students to be convinced that a combination of analytical and graphic ways to solve geometric tasks is useful and reasonable.The traditional sections of learning courses need to be added with a theory of projective and bi-rational transformations. In terms of application simplicity and convenience it is enough to consider the central transformations when solving the applied tasks. These transformations contain a beam of sub-invariant (low-invariant straight lines on which the invariant curve induces non-involution and involution projectivities. The expediency of nonlinear transformations application is shown in the article by a specific example of geometric modeling of the interfacing surface "spar-blade".Implementation of these suggestions will contribute to a real transformation of a traditional course of descriptive geometry to the engineering geometry

  15. 7 CFR 51.2843 - Fairly firm.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly firm. 51.2843 Section 51.2843 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Fairly firm. Fairly firm means that the onion may yield slightly to moderate pressure but is not...

  16. 7 CFR 51.2276 - Color chart.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Walnut Color Chart) to which reference is made in §§ 51.2281 and 51.2282 illustrates the four shades of...

  17. 28 CFR 51.34 - Expedited consideration.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Expedited consideration. 51.34 Section 51... consideration. (a) When a submitting authority is required under State law or local ordinance or otherwise finds... the submission be given expedited consideration. The submission should explain why such consideration...

  18. 7 CFR 51.2284 - Size classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Size classification. 51.2284 Section 51.2284... Size classification. The following classifications are provided to describe the size of any lot... shall conform to the requirements of the specified classification as defined below: (a) Halves. Lot...

  19. 41 CFR 51-5.1 - General.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true General. 51-5.1 Section 51-5.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts... commodities, information such as the latest solicitation and amendments, bid abstracts, procurement history...

  20. Increased FKBP51 in induced sputum cells of chronic obstructive pulmonary disease patients after therapy

    Directory of Open Access Journals (Sweden)

    Holownia A

    2009-12-01

    Full Text Available Abstract Objective Immunophilin FKBP51 assists polypeptide folding, participates in glucocorticoid actions and may play a role in glucocorticoid resistance. FKBP51 is altered in patients with asthma, but its role in chronic obstructive pulmonary disease (COPD characterized by dysregulation of several pro/antiinflammatory genes is less clear. Methods We assessed changes in nuclear/cytosolic FKBP51 protein using SDS-PAGE/WB and FKBP51 mRNA by qRT-PCR in cells isolated from induced sputum of stable COPD patients treated with formoterol/budesonide or formoterol/budesonide/theophylline for 4 wk. Results Expression of FKBP51 was higher in formoterol/budesonide/theophylline-treated patients, compared with formoterol/budesonide group in both cytosolic and nuclear fractions by about 57% and 31%, respectively (P Conclusions Increased FKBP51 in COPD patients treated with formoterol/budesonide/theophylline may be important in altering signaling from corticosteroid receptors.

  1. The Gd{sub 14}Ag{sub 51} structure type and its relation to some complex amalgam structures

    Energy Technology Data Exchange (ETDEWEB)

    Tambornino, Frank; Sappl, Jonathan; Hoch, Constantin, E-mail: constantin.hoch@cup.uni-muenchen.de

    2015-01-05

    Highlights: • The Gd{sub 14}Ag{sub 51} structure type has been revisited on the basis of single crystal diffraction data. • Symmetry analysis from electron density and TEM shows the space group P6/m to be true. • Gd{sub 14}Ag{sub 51} shows good metallic behaviour. • Structure relations to alkali, alkaline-earth and rare-earth metal amalgams can be established. • Complexity values for the RE{sub 14}Ag{sub 51} structure family were calculated. - Abstract: A plethora of binary and ternary intermetallic compounds has been assigned to the Gd{sub 14}Ag{sub 51} structure type, crystallising in the hexagonal system (space group P6/m, a = 1264.30(18) pm, c = 933.58(11) pm for Gd{sub 14}Ag{sub 51}). Starting in the late 1960s, much work has been invested in the structural elucidation of these crystal structures. However, reliable single crystal data are scarce, and most structure type assignments have been performed merely on the basis of powder data. We have redetermined four representatives of the binary RE{sub 14}Ag{sub 51} structure type (RE = Y, Ce, Gd, Tb) with modern high-precision single crystal X-ray methods. The assignment of the Gd{sub 14}Ag{sub 51} structure type to space group P6/m was additionally verified by careful analysis of high resolution transmission electron micrographs. We emphasise the close relation of the Gd{sub 14}Ag{sub 51} structure type to the structures of some recently described amalgams of similar composition focussing on disorder phenomena and structural complexity. Furthermore, we provide detailed information on synthesis as well as electrical and magnetic properties for Gd{sub 14}Ag{sub 51}, the parent compound of this structure family.

  2. A Submillimetre Study of Massive Star Formation Within the W51 Complex and Infrared Dark Clouds

    Science.gov (United States)

    Parsons, Harriet Alice Louise

    Despite its importance the fundamental question of how massive stars form remains unanswered, with improvements to both models and observations having crucial roles to play. To quote Bate et al. (2003) computational models of star formation are limited because "conditions in molecular clouds are not sufficiently well understood to be able to select a representative sample of cloud cores for the initial conditions". It is this notion that motivates the study of the environments within Giant Molecular Clouds (GMCs) and Infrared Dark Clouds (IRDCs), known sites of massive star formation, at the clump and core level. By studying large populations of these objects, it is possible to make conclusions based on global properties. With this in mind I study the dense molecular clumps within one of the most massive GMCs in the Galaxy: the W51 GMC. New observations of the W51 GMC in the 12CO, 13CO and C18O (3-2) transitions using the HARP instrument on the JCMT are presented. With the help of the clump finding algorithm CLUMPFIND a total of 1575 dense clumps are identified of which 1130 are associated with the W51 GMC, yielding a dense mass reservoir of 1.5 × 10^5 M contained within these clumps. Of these clumps only 1% by number are found to be super-critical, yielding a super-critical clump formation efficiency of 0.5%, below current SFE estimates of the region. This indicates star formation within the W51 GMC will diminish over time although evidence from the first search for molecular outflows presents the W51 GMC in an active light with a lower limit of 14 outflows. The distribution of the outflows within the region searched found them concentrated towards the W51A region. Having much smaller sizes and masses, obtaining global properties of clumps and cores within IRDCs required studying a large sample of these objects. To do this pre-existing data from the SCUBA Legacy Catalogue was utilised to study IRDCs within a catalogues based on 8 μm data. This data identified

  3. Characterization of the tank 51 alternate reductant sludge batch 9 slurry sample (HTF-51-15-130)

    Energy Technology Data Exchange (ETDEWEB)

    Reboul, S. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-02-01

    Tank 51 slurry sample HTF-51-15-130 was collected following sludge washing at the Tank Farm. The sample was received at SRNL and then characterized in preparation for qualification of the alternate reductant Sludge Batch 9 (SB9) flowsheet. In this characterization, densities, solids distribution, elemental constituents, anionic constituents, carbon content, and select radioisotopes were quantified.

  4. Diffusion of 51Cr along high-diffusivity paths in Ni-Fe alloys

    International Nuclear Information System (INIS)

    Cermak, J.

    1990-01-01

    Penetration profiles of 51 Cr in polycrystalline alloys Ni-xFe (x = 0, 20, 40, and 60 wt.% Fe) after diffusion anneals at temperatures between 693 and 1473 K are studied. Sectioning of diffusion zones of samples annealed above 858 K is carried out by grinding, at lower temperatures by DC glow discharge sputtering. The concentration of 51 Cr in depth x is assumed to be proportional to relative radioactivity of individual sections. With help of volume and pipe self-diffusion data taken from literature, the temperature dependence of product P = δD g (δ and D g are grain boundary width and grain boundary diffusion coefficient, respectively) is obtained: P = (2.68 - 0.88 +1.3 ) x 10 -11 exp [-(221.3 ± 3.0) kJ/mol/RT]m 3 /s. This result agrees well with the previous measurements of 51 Cr diffusivity in Fe-18 Cr-12 Ni and Fe-21 Cr-31 Ni. It indicates that the mean chemical composition of Fe-Cr-Ni ternary alloys is not a dominant factor affecting the grain boundary diffusivity of Cr in these alloys. (author)

  5. 25 CFR 900.51 - What is an Indian tribe or tribal organization's property management system expected to do?

    Science.gov (United States)

    2010-04-01

    ... Systems Property Management System Standards § 900.51 What is an Indian tribe or tribal organization's... 25 Indians 2 2010-04-01 2010-04-01 false What is an Indian tribe or tribal organization's property management system expected to do? 900.51 Section 900.51 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE...

  6. 16 CFR 1505.51 - Hot surfaces.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Hot surfaces. 1505.51 Section 1505.51 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS... into any opening in the toy. Unless the probe contacts a surface within 3 inches of the plane of the...

  7. 36 CFR 223.51 - Bid monitoring.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Bid monitoring. 223.51 Section 223.51 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND... Bid monitoring. Each Regional Forester shall monitor bidding patterns on timber sales to determine if...

  8. 34 CFR 674.51 - Special definitions.

    Science.gov (United States)

    2010-07-01

    ... from ages 3 through 21, inclusive, who requires special education and related services because he or... 34 Education 3 2010-07-01 2010-07-01 false Special definitions. 674.51 Section 674.51 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION...

  9. 40 CFR 164.51 - Other discovery.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Other discovery. 164.51 Section 164.51... GOVERNING HEARINGS, UNDER THE FEDERAL INSECTICIDE, FUNGICIDE, AND RODENTICIDE ACT, ARISING FROM REFUSALS TO... OTHER HEARINGS CALLED PURSUANT TO SECTION 6 OF THE ACT General Rules of Practice Concerning Proceedings...

  10. 41 CFR 51-4.1 - General.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true General. 51-4.1 Section 51-4.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts... nonprofit agency assigned by the Committee on the basis of the nonprofit agency's articles of incorporation...

  11. GAS SURFACE DENSITY, STAR FORMATION RATE SURFACE DENSITY, AND THE MAXIMUM MASS OF YOUNG STAR CLUSTERS IN A DISK GALAXY. II. THE GRAND-DESIGN GALAXY M51

    International Nuclear Information System (INIS)

    González-Lópezlira, Rosa A.; Pflamm-Altenburg, Jan; Kroupa, Pavel

    2013-01-01

    We analyze the relationship between maximum cluster mass and surface densities of total gas (Σ gas ), molecular gas (Σ H 2 ), neutral gas (Σ H I ), and star formation rate (Σ SFR ) in the grand-design galaxy M51, using published gas data and a catalog of masses, ages, and reddenings of more than 1800 star clusters in its disk, of which 223 are above the cluster mass distribution function completeness limit. By comparing the two-dimensional distribution of cluster masses and gas surface densities, we find for clusters older than 25 Myr that M 3rd ∝Σ H I 0.4±0.2 , whereM 3rd is the median of the five most massive clusters. There is no correlation withΣ gas ,Σ H2 , orΣ SFR . For clusters younger than 10 Myr, M 3rd ∝Σ H I 0.6±0.1 and M 3rd ∝Σ gas 0.5±0.2 ; there is no correlation with either Σ H 2 orΣ SFR . The results could hardly be more different from those found for clusters younger than 25 Myr in M33. For the flocculent galaxy M33, there is no correlation between maximum cluster mass and neutral gas, but we have determined M 3rd ∝Σ gas 3.8±0.3 , M 3rd ∝Σ H 2 1.2±0.1 , and M 3rd ∝Σ SFR 0.9±0.1 . For the older sample in M51, the lack of tight correlations is probably due to the combination of strong azimuthal variations in the surface densities of gas and star formation rate, and the cluster ages. These two facts mean that neither the azimuthal average of the surface densities at a given radius nor the surface densities at the present-day location of a stellar cluster represent the true surface densities at the place and time of cluster formation. In the case of the younger sample, even if the clusters have not yet traveled too far from their birth sites, the poor resolution of the radio data compared to the physical sizes of the clusters results in measuredΣ that are likely quite diluted compared to the actual densities relevant for the formation of the clusters.

  12. 7 CFR 51.15 - Financial interest of inspector.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Financial interest of inspector. 51.15 Section 51.15 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... STANDARDS) Regulations 1 Inspection Service § 51.15 Financial interest of inspector. No inspector shall...

  13. 40 CFR 230.51 - Recreational and commercial fisheries.

    Science.gov (United States)

    2010-07-01

    .... 230.51 Section 230.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... Potential Effects on Human Use Characteristics § 230.51 Recreational and commercial fisheries. (a... these impacts can be of short duration or prolonged, depending upon the physical and chemical impacts of...

  14. 7 CFR 1212.51 - Financial statements.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Financial statements. 1212.51 Section 1212.51... statements. (a) The Board shall prepare and submit financial statements to the Department on a periodic basis. Each such financial statement shall include, but not be limited to, a balance sheet, income statement...

  15. 41 CFR 51-10.140 - Employment.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Employment. 51-10.140... WHO ARE BLIND OR SEVERELY DISABLED § 51-10.140 Employment. No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity...

  16. 38 CFR 51.190 - Infection control.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Infection control. 51.190... FOR NURSING HOME CARE OF VETERANS IN STATE HOMES Standards § 51.190 Infection control. The facility management must establish and maintain an infection control program designed to provide a safe, sanitary, and...

  17. 9 CFR 147.51 - Authorized laboratory minimum requirements.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Authorized laboratory minimum requirements. 147.51 Section 147.51 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... Authorized Laboratories and Approved Tests § 147.51 Authorized laboratory minimum requirements. These minimum...

  18. 49 CFR 1242.55 - Administration (account XX-51-01).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Administration (account XX-51-01). 1242.55 Section...-Transportation § 1242.55 Administration (account XX-51-01). Separate common expenses according to distribution of common expenses in the following accounts: Engine Crews (XX-51-56) Train Crews (XX-51-57) Dispatching...

  19. Direct molecular diagnosis of aspergillosis and CYP51A profiling from respiratory samples of French patients

    Directory of Open Access Journals (Sweden)

    Yanan Zhao

    2016-07-01

    Full Text Available Background: Microbiological diagnosis of aspergillosis and triazole resistance is limited by poor culture yield. To better estimate this shortcoming, we compared culture and molecular detection of A. fumigatus in respiratory samples from French patients at risk for aspergillosis. Methods: A total of 97 respiratory samples including bronchoalveolar lavages (BAL, bronchial aspirates (BA, tracheal aspirates, sputa, pleural fluids, and lung biopsy were collected from 33 patients having invasive aspergillosis (n=12, chronic pulmonary aspergillosis (n=3, allergic bronchopulmonary aspergillosis (n=7 or colonization (n=11 and 28 controls. Each specimen was evaluated by culture, pan-Aspergillus qPCR, and CYP51A PCR and sequencing. Results: One A. flavus and 19 A. fumigatus with one multiazole resistant strain (5.3% were cultured from 20 samples. Culture positivity was 62.5%, 75%, 42.9%, and 15.8% in ABPA, CPA, IA and colonized patients, respectively. Aspergillus detection rate was significantly higher by pan-Aspergillus qPCR than by culture in IA (90.5% vs 42.9%; P<0.05 and colonization group (73.7% vs 15.8%; P<0.05. The CYP51A PCR found one TR34/L98H along with 5 novel cyp51A mutations (4 non-synonymous and 1 promoter mutations, yet no association can be established currently between these novel mutations and azole resistance. The analysis of 11 matched pairs of BA and BAL samples found that 9/11 BA carried greater fungal load than BAL and CYP51A detection was more sensitive in BA than in BAL. Conclusion: Direct molecular detection of Aspergillus spp. and azole resistance markers are useful adjunct tools for comprehensive aspergillosis diagnosis. The observed superior diagnostic value of BAs to BAL fluids warrants more in-depth study.

  20. Electron Temperatures in W51 Complex from High Resolution, Low ...

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... We have made continuum radio observations of these HII regions of the W51 complex at 240, 610, 1060 and 1400 MHz using GMRT with lower resolution (20'' × 15'') at the lowest frequency. The observed spectra of the prominent thermal subcomponents of W51 have been fitted to a free-free emission ...

  1. Comparative analysis of cytokeratin 15, TDAG51, cytokeratin 20 and androgen receptor in sclerosing adnexal neoplasms and variants of basal cell carcinoma.

    Science.gov (United States)

    Evangelista, Mara Therese P; North, Jeffrey P

    2015-11-01

    Desmoplastic trichoepithelioma (DTE), morpheaform basal cell carcinoma (BCC) and microcystic adnexal carcinoma (MAC) are sclerosing adnexal neoplasms with overlapping histopathologic features. We compared cytokeratin 15, (CK15), T-cell death-associated gene 51 (TDAG51), cytokeratin 20 (CK20) and androgen receptor (AR) in differentiating these tumors and assessed their expression in BCC subtypes. Fifteen DTE, 15 infundibulocystic BCC, 18 micronodular BCC, 18 morpheaform BCC and 6 MAC were assessed for CK15, TDAG51, CK20 and AR expression. Quantitative CK15 staining was higher in DTE compared with BCC (p < 0.0001) and MAC (p = 0.02). Quantitative TDAG51 staining was higher in DTE than BCC (p < 0.0001). The CK20+AR- immunophenotype was 100% sensitive and specific in diagnosing DTE. The CK20-AR+ immunophenotype was 95.24% specific and 83.33% sensitive for BCC. The CK20-AR- immunophenotype was 83.33% sensitive and 90.91% specific for MAC. CK15, CK20 and AR were positive in 87, 53 and 67% of infundibulocystic BCC cases, respectively. Combination of CK20 and AR best differentiated these sclerosing adnexal neoplasms. Greater positivity for CK15 and TDAG51 generally favors benign lesions. Infundibulocystic BCC has higher CK20 and lower AR immunopositivity than other BCC variants and a high degree of CK15 and TDAG51 positivity. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. 7 CFR 51.1435 - U.S. Commercial Pieces.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial Pieces. 51.1435 Section 51.1435 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... STANDARDS) United States Standards for Grades of Shelled Pecans Grades § 51.1435 U.S. Commercial Pieces. The...

  3. 7 CFR 51.1433 - U.S. Commercial Halves.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial Halves. 51.1433 Section 51.1433 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... STANDARDS) United States Standards for Grades of Shelled Pecans Grades § 51.1433 U.S. Commercial Halves. The...

  4. 7 CFR 51.1143 - U.S. No. 1.

    Science.gov (United States)

    2010-01-01

    ..., (22) Other means. (d) For tolerances see § 51.1151. (e) Internal quality: Lots meeting the internal... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1. 51.1143 Section 51.1143 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  5. 38 CFR 51.180 - Pharmacy services.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Pharmacy services. 51.180... FOR NURSING HOME CARE OF VETERANS IN STATE HOMES Standards § 51.180 Pharmacy services. The facility... aspects of the provision of pharmacy services in the facility; (2) Establishes a system of records of...

  6. Identification of CD4+ T-cell Epitopes on Mycobacterium Tuberculosis- Secreted MPB51 Protein in C57BL/6 Mice

    Directory of Open Access Journals (Sweden)

    A.R. Rafiei

    2006-01-01

    Full Text Available Introduction & Objective: Both CD4+ type 1 helper (Th1 cells and CD8+ T cells play effective roles in protection against Mycobacterium tuberculosis infection. DNA vaccine encoding MPB51 can induce Th1-type immune responses and protective immunity upon challenge with M.tuberculosis. This study address to identify T-cell immunodominant epitopes on MPB51 in C57BL/6 mice.Materials & Methods : We cloned DNA encoding MPB51 molecule in pCI plasmid. After constructing MPB51 DNA-covered gold cartridge, C57BL/6 mice were immunized by using a gene gun system. Two weeks after the last immunization, the immune spleen cells were cultured in the presence of a synthetic overlapping library peptides covering the mature MPB51 sequence or medium alone. Intracellular and cell culture supernatant gamma interferon (IFN- production was analyzed using flow cytometry and ELISA, respectively.Results : Mapping of T-cell epitopes on MPB51 molecule was performed in the spleen lymphocytes restimulated by 20-mer overlapping synthetic peptides of mature MPB51 sequence. Flow cytometric analysis with intracellular IFN- and the T-cell phenotype revealed that P171-190 and P191-210 peptides contain immunodominant CD4+ T-cell epitopes. Further analysis by using T-cell subset depletion and serial peptide dilution revealed that P171 and p191 are H2-Ab-restricted dominant and subdominant CD4+ T cell epitopes, respectively. Conclusion: This study proved that vaccination with plasmid DNA encoding M. tuberculosis-secreted MPB51 protein not only induce CD4+ T cells immune response but also is an appropriate method for identifying immunogenic peptides.

  7. 42 CFR 51.21 - Contracts for program operations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Contracts for program operations. 51.21 Section 51... APPLICABLE TO THE PROTECTION AND ADVOCACY FOR INDIVIDUALS WITH MENTAL ILLNESS PROGRAM Program Administration and Priorities § 51.21 Contracts for program operations. (a) An eligible P&A system should work...

  8. 41 CFR 109-28.000-51 - Storage guidelines.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Storage guidelines. 109-28.000-51 Section 109-28.000-51 Public Contracts and Property Management Federal Property Management...-STORAGE AND DISTRIBUTION § 109-28.000-51 Storage guidelines. (a) Indoor storage areas should be arranged...

  9. 7 CFR 51.1148 - U.S. No. 2.

    Science.gov (United States)

    2010-01-01

    ... tolerances see § 51.1151. (e) Internal quality: Lots meeting the internal requirements for “U.S. Grade AA... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2. 51.1148 Section 51.1148 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  10. 38 CFR 10.51 - Payments to minor child.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Payments to minor child. 10.51 Section 10.51 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUSTED COMPENSATION Payments § 10.51 Payments to minor child. Payments to minor child through legal guardian, natural...

  11. 37 CFR 2.51 - Drawing required.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Drawing required. 2.51... COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Drawing § 2.51 Drawing required. (a) In an application under section 1(a) of the Act, the drawing of the mark must be a substantially exact representation of the mark...

  12. STS-51B Crew Portrait

    Science.gov (United States)

    1985-01-01

    The crew assigned to the STS-51B mission included (seated left to right) Robert F. Overmyer, commander; and Frederick D. Gregory, pilot. Standing, left to right, are Don L. Lind, mission specialist; Taylor G. Wang, payload specialist; Norman E. Thagard, mission specialist; William E. Thornton, mission specialist; and Lodewijk van den Berg, payload specialist. Launched aboard the Space Shuttle Challenger on April 29, 1985 at 12:02:18 pm (EDT), the STS-51A mission's primary payload was the Spacelab-3.

  13. 7 CFR 51.2731 - U.S. Spanish Splits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Spanish Splits. 51.2731 Section 51.2731... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2731 U.S. Spanish Splits. “U.S. Spanish Splits” consists of shelled Spanish type peanut kernels which are split or broken...

  14. 40 CFR 51.117 - Additional provisions for lead.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Additional provisions for lead. 51.117... Additional provisions for lead. In addition to other requirements in §§ 51.100 through 51.116 the following requirements apply to lead. To the extent they conflict, there requirements are controlling over those of the...

  15. 25 CFR 36.51 - Standard XVIII-Office of Indian Education Programs and Agency monitoring and evaluation...

    Science.gov (United States)

    2010-04-01

    ... XVIII—Office of Indian Education Programs and Agency monitoring and evaluation responsibilities. (a) The... 25 Indians 1 2010-04-01 2010-04-01 false Standard XVIII-Office of Indian Education Programs and Agency monitoring and evaluation responsibilities. 36.51 Section 36.51 Indians BUREAU OF INDIAN AFFAIRS...

  16. Anisotropic diffusion of 51Cr in Zr-α monocrystals

    International Nuclear Information System (INIS)

    Varela, N.; Balart, S.; Tendler, R.

    1983-01-01

    The volume diffusion coefficients of the fast-diffusing solute 51 Cr were obtained in oriented α-Zr single-crystals, in the directions parallel and perpendicular to the c axis. The dependence of those diffusion coefficients with temperature was also measured between 750 0 C and 848 0 C. Single-crystals were grown by thermal cycling through the transformation α β (863 0 C). Diffusion coefficients were measured using the 'thin film' method. In some experiments non-gaussian penetration profiles were obtained and this behaviour is analyzed in the Appendix. The diffusion of 51 Cr is faster in the c axis direction, with Q sub(//) (1.59 eV) [pt

  17. 7 CFR 51.883 - U.S. Fancy Export.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Fancy Export. 51.883 Section 51.883 Agriculture... Standards for Grades of Table Grapes (European or Vinifera Type) 1 Grades § 51.883 U.S. Fancy Export. “U.S. Fancy Export” consists of grapes which meet the requirements for U.S. Fancy Table, except that bunches...

  18. 18 CFR 420.51 - Hydroelectric power plant water use charges.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Hydroelectric power... BASIN COMMISSION ADMINISTRATIVE MANUAL BASIN REGULATIONS-WATER SUPPLY CHARGES Hydroelectric Power Water Use Charges § 420.51 Hydroelectric power plant water use charges. (a) Annual base charges. Owners of...

  19. 17 CFR 270.2a51-2 - Definitions of beneficial owner for certain purposes under sections 2(a)(51) and 3(c)(7) and...

    Science.gov (United States)

    2010-04-01

    ... COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY ACT OF 1940 § 270.2a51-2 Definitions of... exception set forth in this subparagraph, be excluded from the definition of investment company solely by... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions of beneficial...

  20. Dynamic hyperbolic geometry: building intuition and understanding mediated by a Euclidean model

    Science.gov (United States)

    Moreno-Armella, Luis; Brady, Corey; Elizondo-Ramirez, Rubén

    2018-05-01

    This paper explores a deep transformation in mathematical epistemology and its consequences for teaching and learning. With the advent of non-Euclidean geometries, direct, iconic correspondences between physical space and the deductive structures of mathematical inquiry were broken. For non-Euclidean ideas even to become thinkable the mathematical community needed to accumulate over twenty centuries of reflection and effort: a precious instance of distributed intelligence at the cultural level. In geometry education after this crisis, relations between intuitions and geometrical reasoning must be established philosophically, rather than taken for granted. One approach seeks intuitive supports only for Euclidean explorations, viewing non-Euclidean inquiry as fundamentally non-intuitive in nature. We argue for moving beyond such an impoverished approach, using dynamic geometry environments to develop new intuitions even in the extremely challenging setting of hyperbolic geometry. Our efforts reverse the typical direction, using formal structures as a source for a new family of intuitions that emerge from exploring a digital model of hyperbolic geometry. This digital model is elaborated within a Euclidean dynamic geometry environment, enabling a conceptual dance that re-configures Euclidean knowledge as a support for building intuitions in hyperbolic space-intuitions based not directly on physical experience but on analogies extending Euclidean concepts.

  1. RAD51B in Familial Breast Cancer

    OpenAIRE

    Pelttari, L.M.; Khan, S.; et al.,

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737\\ud and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast\\ud cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer\\ud predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the\\ud coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for\\ud identifi...

  2. RAD51B in familial breast cancer

    OpenAIRE

    Pelttari, LM; Khan, S; Vuorela, M; Kiiski, JI; Vilske, S; Nevanlinna, V; Ranta, S; Schleutker, J; Winqvist, R; Kallioniemi, A; Dörk, T; Bogdanova, NV; Figueroa, J; Pharoah, PDP; Schmidt, MK

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possi...

  3. National instrument 51-101 : new rules are coming

    Energy Technology Data Exchange (ETDEWEB)

    Story, C.A. [Fraser Milner Casgrain LLP, Calgary, AB (Canada)

    2003-07-01

    This paper provides general information about National Instrument 51-101 developed by the Alberta Securities Commission. NI 51-101 requires public companies to file an annual statement regarding estimated oil and gas reserves and related information. The report must be accompanied by an independent qualified evaluator's report and any other information regarding oil and gas activities. NI 51-101 incorporates reserves definitions developed by the reserves committee at the Canadian Institute of Mining, Metallurgy and Petroleum (CIM). The paper also outlines some of the issues that should be considered in purchases, sales, mergers, and acquisitions. This paper described the timing and transition of NI 51-101 and included a list of information that must be disclosed in the annual statement. Materiality standards, and material change disclosure was also described along with issuer obligations. It was noted that NI 51-101 will impact prospectus disclosures as well as memorandum disclosures.

  4. 47 CFR 78.51 - Remote control operation.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Remote control operation. 78.51 Section 78.51 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY... shall also be equipped with suitable devices for observing the overall characteristics of the...

  5. 7 CFR 51.2116 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... blanchable varieties within the “California” Marketing Classification. In addition, Nonpareil or similar... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2116 Section 51.2116 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...

  6. 7 CFR 51.1154 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.1154 Section 51.1154 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... varietal characteristics. Similar varietal characteristics means that the fruits in any container are...

  7. 7 CFR 51.3202 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.3202 Section 51.3202 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Similar varietal characteristics. Similar varietal characteristics means that the onions in any container...

  8. Experimental infection of nontarget species of rodents and birds with Brucella abortus strain RB51 vaccine

    Science.gov (United States)

    Januszewski, M.C.; Olsen, S.C.; McLean, R.G.; Clark, L.; Rhyan, Jack C.

    2001-01-01

    The Brucella abortus vaccine strain RB51 (SRB51) is being considered for use in the management of bnucellosis in wild bison (Bison bison) and elk (Cervus elaphus) populations in the Greater Yellowstone Area (USA). Evaluation of the vaccines safety in non-target species was considered necessary prior to field use. Between June 1998 and December 1999, ground squirrels (Spermophilus richardsonii, n = 21), deer mice (Peromyscus maniculatus, n = 14), prairie voles (Microtus ochrogaster, n = 21), and ravens (Corvus corax, n = 13) were orally inoculated with SRB51 or physiologic saline. Oral and rectal swabs and blood samples were collected for bacteriologic evaluation. Rodents were necropsied at 8 to 10 wk and 12 to 21 wk post inoculation (PI), and ravens at 7 and 11 wk PI. Spleen, liver and reproductive tissues were collected for bacteriologic and histopathologic evaluation. No differences in clinical signs, appetite, weight loss or gain, or activity were observed between saline- and SRB51-inoculated animals in all four species. Oral and rectal swabs from all species were negative throughout the study. In tissues obtained from SRB51-inoculated animals, the organism was isolated from six of seven (86%) ground squirrels, one of six (17%) deer mice, none of seven voles, and one of five (20%) ravens necropsied at 8, 8, 10, and 7 wk PI, respectively. Tissues from four of seven (57%) SRB51-inoculated ground squirrels were culture positive for the organism 12 wk PI; SRB51 was not recovered from deer mice, voles. or ravens necropsied 12, 21, or 11 wk, respectively, PI. SRB51 was not recovered from saline-inoculated ground squirrels, deer mice, or voles at any time but was recovered from one saline-inoculated raven at necropsy, 7 wk PI, likely attributable to contact with SRB51-inoculated ravens in an adjacent aviary room. Spleen was time primary tissue site of colonization in ground squirrels, followed by the liver and reproductive organs. The results indicate oral exposure to

  9. Phase transformation in nanocrystalline α-quartz GeO2 up to 51.5 GPa

    International Nuclear Information System (INIS)

    Wang, H; Liu, J F; Wu, H P; He, Y; Chen, W; Wang, Y; Zeng, Y W; Wang, Y W; Luo, C J; Liu, J; Hu, T D; Stahl, K; Jiang, J Z

    2006-01-01

    The high-pressure behaviour of nanocrystalline α-quartz GeO 2 (q-GeO 2 ) with average crystallite sizes of 40 and 260 nm has been studied by in situ high-pressure synchrotron radiation x-ray diffraction measurements up to about 51.5 GPa at ambient temperature. Two phase transformations, q-GeO 2 to amorphous GeO 2 and amorphous GeO 2 to monoclinic GeO 2 , are detected. The onset and end of the transition pressures for the q-GeO 2 -to-amorphous GeO 2 phase transition are found to be approximately 10.8 and 14.9 GPa for the 40 nm q-GeO 2 sample, and 9.5 and 12.4 GPa for the 260 nm q-GeO 2 sample, respectively. The mixture of amorphous and monoclinic GeO 2 phases remains up to 51.5 GPa during compression and even after pressure release. This result strongly suggests that the difference of free energy between the amorphous phase and the monoclinic phase might be small. Consequently, defects in the starting material, which alter the free energies of the amorphous phase and the monoclinic phase, may play a key role for the phase transformation of q-GeO 2

  10. 7 CFR 51.2085 - Fairly uniform color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly uniform color. 51.2085 Section 51.2085 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... color. Fairly uniform color means that the shells do not show excessive variation in color, whether...

  11. 7 CFR 51.1550 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.1550 Section 51.1550 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the potatoes in any lot have the same general shape...

  12. 7 CFR 51.2756 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2756 Section 51.2756 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the peanut kernels in the lot are not of distinctly...

  13. 7 CFR 51.763 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.763 Section 51.763 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the fruits in any container are similar in color and...

  14. 7 CFR 51.3057 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.3057 Section 51.3057 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the avocados in any container are similar in shape...

  15. 7 CFR 51.2714 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2714 Section 51.2714 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the peanut kernels in the lot are not of distinctly...

  16. 7 CFR 51.603 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.603 Section 51.603 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the stalks in any container have the same character...

  17. 7 CFR 51.2650 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2650 Section 51.2650 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the cherries in any container are similar in color...

  18. 41 CFR 51-6.11 - Quality complaints.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Quality complaints. 51-6.11 Section 51-6.11 Public Contracts and Property Management Other Provisions Relating to Public... commodities received from Defense Logistics Agency supply centers, General Services Administration supply...

  19. 47 CFR 51.715 - Interim transport and termination pricing.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Interim transport and termination pricing. 51.715 Section 51.715 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Telecommunications Traffic § 51.715 Interim transport and termination pricing. (a) Upon request from a...

  20. 41 CFR 105-1.109-51 - Arrangement.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Arrangement. 105-1.109-51 Section 105-1.109-51 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

  1. 7 CFR 51.2832 - U.S. Commercial.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Commercial. 51.2832 Section 51.2832 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing.... Commercial. U.S. Commercial consists of onions which meet the following requirements: (a) Basic requirements...

  2. 7 CFR 51.1906 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.1906 Section 51.1906 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the tomatoes are alike as to color, i.e., bright red...

  3. 50 CFR 14.51 - Inspection of wildlife.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Inspection of wildlife. 14.51 Section 14.51 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  4. 7 CFR 51.2947 - Method of inspection.

    Science.gov (United States)

    2010-01-01

    ... internal defects. The nuts must meet the requirements for both external and internal quality in order to... 7 Agriculture 2 2010-01-01 2010-01-01 false Method of inspection. 51.2947 Section 51.2947 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...

  5. RAD51B in Familial Breast Cancer

    DEFF Research Database (Denmark)

    Pelttari, Liisa M; Khan, Sofia; Vuorela, Mikko

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition......, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD......51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC) that were genotyped on a custom chip (iCOGS). We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients...

  6. CORROSION RATE OF STEELS DX51D AND S220GD IN DIFFERENT CORROSION ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Alina Crina CIUBOTARIU

    2016-06-01

    Full Text Available Corrosion in the marine environment is an important issue because the costs causes by marine corrosion increased year upon year. It is necessary a correctly approach to materials selection, protection and corrosion control to reduce this burden of wasted materials, wasted energy and wasted money. Many different types of corrosion attack can be observed to structures, ships and other equipment used in sea water service. Shipping containers are exposed to various corrosive mediums like as airborne salt, industrial pollutants, rain and saltwater. Transport damage during loading onto and unloading off trucks, train beds and ships breaches the paint coating which further contributes to corrosion. The result is shortened container life and high costs for container repair or replacement. The paper intends to evaluate, by gravimetric method, the corrosion rate and corrosion penetration rate of two types of carbon steel DX51D and S220GD. Carbon steel DX51D and hot-dip galvanized steel S220GD are used in marine and industrial applications for buildings cargo vessels, container ships and oil tankers. For testing it was used different corrosive environments: 5% NaOH solution; 5% HCL solution and 0.5M NaCl solution. The samples were immersed in 400mL of testing solution for exposure period of 28 days. Periodically at 3 days, 7 days, 14 days, 21 days and 28 days was measured de mass loss and evaluate the corrosion rate and corrosion stability coefficient. The steel DX51D was stable in 5% NaOH solution for 28 days, the values of corrosion stability coefficient was 7 after 3 days and 6 after 28 days of immersion in corrosive medium. In 5% HCL solution steels DX51D and S220GD was completely corroded in 21 days with a corrosion stability coefficient equal with 9 for 7 days and 8 for 21 days of immersion in corrosive solution. It was observed a good resistance for 3 days in 0.5M NaCl solution with a corrosion stability coefficient equal with 5, but after that

  7. Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51

    Science.gov (United States)

    Thirty-one bison heifers were randomly assigned to saline (control; n=7) or single vaccination (n=24) with 1010 CFU of B. abortus strain RB51 (RB51). Some vaccinated bison were randomly selected for booster vaccination with 10**10 CFU of RB51 at 11 months after initial vaccination (n=16). When comp...

  8. PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.

    Science.gov (United States)

    Pinho, Sandra; Lacombe, Julie; Hanoun, Maher; Mizoguchi, Toshihide; Bruns, Ingmar; Kunisaki, Yuya; Frenette, Paul S

    2013-07-01

    The intermediate filament protein Nestin labels populations of stem/progenitor cells, including self-renewing mesenchymal stem cells (MSCs), a major constituent of the hematopoietic stem cell (HSC) niche. However, the intracellular location of Nestin prevents its use for prospective live cell isolation. Hence it is important to find surface markers specific for Nestin⁺ cells. In this study, we show that the expression of PDGFRα and CD51 among CD45⁻ Ter119⁻ CD31⁻ mouse bone marrow (BM) stromal cells characterizes a large fraction of Nestin⁺ cells, containing most fibroblastic CFUs, mesenspheres, and self-renewal capacity after transplantation. The PDGFRα⁺ CD51 ⁺subset of Nestin⁺ cells is also enriched in major HSC maintenance genes, supporting the notion that niche activity co-segregates with MSC activity. Furthermore, we show that PDGFRα⁺ CD51⁺ cells in the human fetal BM represent a small subset of CD146⁺ cells expressing Nestin and enriched for MSC and HSC niche activities. Importantly, cultured human PDGFRα⁺ CD51⁺ nonadherent mesenspheres can significantly expand multipotent hematopoietic progenitors able to engraft immunodeficient mice. These results thus indicate that the HSC niche is conserved between the murine and human species and suggest that highly purified nonadherent cultures of niche cells may represent a useful novel technology to culture human hematopoietic stem and progenitor cells.

  9. 10 CFR 51.90 - Final environmental impact statement-general.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Final environmental impact statement-general. 51.90... Implementing Section 102(2) Final Environmental Impact Statements-General Requirements § 51.90 Final environmental impact statement—general. After receipt and consideration of comments requested pursuant to §§ 51...

  10. Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52

    International Nuclear Information System (INIS)

    Veelen, Lieneke R. van; Essers, Jeroen; Rakt, Mandy W.M.M. van de; Odijk, Hanny; Pastink, Albert; Zdzienicka, MaIgorzata Z.; Paulusma, Coen C.; Kanaar, Roland

    2005-01-01

    Homologous recombination is of major importance for the prevention of genomic instability during chromosome duplication and repair of DNA damage, especially double-strand breaks. Biochemical experiments have revealed that during the process of homologous recombination the RAD52 group proteins, including Rad51, Rad52 and Rad54, are involved in an essential step: formation of a joint molecule between the broken DNA and the intact repair template. Accessory proteins for this reaction include the Rad51 paralogs and BRCA2. The significance of homologous recombination for the cell is underscored by the evolutionary conservation of the Rad51, Rad52 and Rad54 proteins from yeast to humans. Upon treatment of cells with ionizing radiation, the RAD52 group proteins accumulate at the sites of DNA damage into so-called foci. For the yeast Saccharomyces cerevisiae, foci formation of Rad51 and Rad54 is abrogated in the absence of Rad52, while Rad51 foci formation does occur in the absence of the Rad51 paralog Rad55. By contrast, we show here that in mammalian cells, Rad52 is not required for foci formation of Rad51 and Rad54. Furthermore, radiation-induced foci formation of Rad51 and Rad54 is impaired in all Rad51 paralog and BRCA2 mutant cell lines tested, while Rad52 foci formation is not influenced by a mutation in any of these recombination proteins. Despite their evolutionary conservation and biochemical similarities, S. cerevisiae and mammalian Rad52 appear to differentially contribute to the DNA-damage response

  11. Assessment of canine intestinal permeability, using 51Cr-labeled ethylenediaminetetraacetate

    International Nuclear Information System (INIS)

    Hall, E.J.; Batt, R.M.; Brown, A.

    1989-01-01

    The 51 Cr-labeled EDTA was validated as a suitable permeability probe in dogs for measurement of passive, unmediated diffusion across intestinal mucosa via intercellular pathways. The 51 Cr-labeled EDTA was stable in aqueous solution and did not bind to biologic tissue and fluids. After incubation of 51 Cr-labeled EDTA in isolated jejunal loops, analytic subcellular fractionation of jejunal mucosa on reorientating sucrose-density gradients was performed, and no association of 51 Cr-labeled EDTA with particulate intracellular organelles was detected. Intravenously administered 51 Cr-labeled EDTA was rapidly and completely excreted in urine. Intestinal permeability to 51 Cr-labeled EDTA after oral administration was assessed in healthy dogs. The percentage of the administered dose of 51 Cr-labeled EDTA excreted in the urine in 24 hours ranged from 2.3 to 17.6% (median, 13%)

  12. 7 CFR 301.51-2 - Regulated articles.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated articles. 301.51-2 Section 301.51-2... Regulated articles. The following are regulated articles: (a) Firewood (all hardwood species), and green... (sycamore), Populus (poplar), Salix (willow), Sorbus (mountain ash), and Ulmus (elm). (b) Any other article...

  13. 41 CFR 51-6.2 - Allocation process.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Allocation process. 51-6.2 Section 51-6.2 Public Contracts and Property Management Other Provisions Relating to Public... to furnish definite quantities of commodities or specific services upon receipt of an order from the...

  14. 42 CFR 51c.105 - Accord with health planning.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Accord with health planning. 51c.105 Section 51c... COMMUNITY HEALTH SERVICES General Provisions § 51c.105 Accord with health planning. A grant may be made... approval by the appropriate health planning agencies have been met. ...

  15. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ...: Discrimination prohibited. 51-10.149 Section 51-10.149 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  16. 41 CFR 51-10.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-07-01

    ... against discrimination. 51-10.130 Section 51-10.130 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED... THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.130 General...

  17. 46 CFR 111.51-3 - Protection of vital equipment.

    Science.gov (United States)

    2010-10-01

    ...-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-3 Protection of vital equipment. (a) The coordination of overcurrent protective devices must be demonstrated for all potential... 46 Shipping 4 2010-10-01 2010-10-01 false Protection of vital equipment. 111.51-3 Section 111.51-3...

  18. Simultaneous ATM/BRCA1/RAD51 expression variations associated with prognostic factors in Iranian sporadic breast cancer patients.

    Science.gov (United States)

    Hallajian, Zeinab; Mahjoubi, Frouzandeh; Nafissi, Nahid

    2017-07-01

    DNA double-strand breaks (DSBs) as a serious lesion are repaired by non-homologous end-joining and homologous recombination pathways. ATM, BRCA1, RAD51 genes are involved in HR pathways. While some studies have revealed individual expression changes of these genes in different types of cancer, there are limited studies attempting to evaluate correlation of expression variations of these genes in breast cancer pathogenesis. This study aimed to determine RAD51, ATM and BRCA1 gene expression level and its association with clinicopathological factors in fresh breast cancer tissues. Moreover, this study evaluates potential correlations among expression levels of these genes. 50 breast cancer tissues were collected and examined for BRCA1, RAD51 and ATM gene expression by Real Time PCR. Expression changes were analyzed with REST software version 2009. mRNA expression was reduced in all these three genes when compared with β-Actin as a control gene (P value  ATM, BRCA1 and RAD51 gene down expression (P value  ATM with stage (P value  < 0.05), necrosis (P value  < 0.05), perineural invasion (P value  < 0.05), vascular invasion (P value  < 0.01), malignancy (P value  ≤ 0.001), PR (P value  < 0.05) and ER status (P value  < 0.01). In addition, there was a significant association between down expression of BRCA1 with Ki67 (P value  ≤ 0.001). Moreover, there was a significant association between down expression of RAD51 with lymph node involvement (P value  < 0.01), auxiliary lymph node metastasis (P value  = 0.01), age (P = 0.001), grade (P value  < 0.05) and PR status (P value  < 0.05). This study suggests association between expression changes in several DSB repair genes in a common functional pathway in breast cancer and the significant association between abnormal expression of these genes and important clinical prognostic factors.

  19. 9 CFR 51.4 - Record of tests.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Record of tests. 51.4 Section 51.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... number of each brucellosis reactor registered animal. A copy of the applicable test record shall be given...

  20. 29 CFR 4.51 - Prevailing in the locality determinations.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Prevailing in the locality determinations. 4.51 Section 4.51... Procedures § 4.51 Prevailing in the locality determinations. (a) Information considered. The minimum monetary... benefits contained in collective bargaining agreements where they have been determined to prevail in a...

  1. 7 CFR 51.309 - Condition after storage or transit.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Condition after storage or transit. 51.309 Section 51... STANDARDS) United States Standards for Grades of Apples Condition After Storage Or Transit § 51.309 Condition after storage or transit. Decay, scald, or any other deterioration which may have developed on...

  2. 7 CFR 51.1146 - U.S. No. 1 Russet.

    Science.gov (United States)

    2010-01-01

    .... (a) For tolerances see § 51.1151. (b) Internal quality: Lots meeting the internal requirements for “U... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Russet. 51.1146 Section 51.1146 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  3. 7 CFR 51.1144 - U.S. No. 1 Golden.

    Science.gov (United States)

    2010-01-01

    ...) For tolerances see § 51.1151. (b) Internal quality: Lots meeting the internal requirements for “U.S... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Golden. 51.1144 Section 51.1144 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  4. A Proof of the Converse of the Pythagorean Proposition

    Science.gov (United States)

    Scimone, Aldo

    2009-01-01

    The article presents a demonstration of the converse of the Pythagorean Theorem based on the "reductio ad absurdum". This is necessary to overcome the discrepancy, noticed by pupils, between the Euclidean purpose to demonstrate that the given triangle is right-angled and the auxiliary figure by which the given triangle is drawn as if it were…

  5. 7 CFR 51.2833 - U.S. No. 1 Boilers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Boilers. 51.2833 Section 51.2833 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...) Grades § 51.2833 U.S. No. 1 Boilers. U.S. No. 1 Boilers consists of onions which meet all the...

  6. 7 CFR 51.1309 - Condition after storage or transit.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Condition after storage or transit. 51.1309 Section 51... STANDARDS) United States Standards for Winter Pears 1 Condition After Storage Or Transit § 51.1309 Condition after storage or transit. Decay, scald or other deterioration which may have developed on pears after...

  7. 7 CFR 51.1268 - Condition after storage or transit.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Condition after storage or transit. 51.1268 Section 51... STANDARDS) United States Standards for Summer and Fall Pears 1 Condition After Storage Or Transit § 51.1268 Condition after storage or transit. Decay, scald, or other deterioration which may have developed on pears...

  8. 7 CFR 51.1149 - U.S. No. 2 Russet.

    Science.gov (United States)

    2010-01-01

    ... tolerances see § 51.1151. (b) Internal quality: Lots meeting the internal requirements for “U.S. Grade AA... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Russet. 51.1149 Section 51.1149 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  9. 28 CFR 104.51 - Payments to eligible individuals.

    Science.gov (United States)

    2010-07-01

    ... COMPENSATION FUND OF 2001 Payment of Claims § 104.51 Payments to eligible individuals. Not later than 20 days... compensation due a claimant under the Fund, the Special Master shall authorize payment to such claimant of the...

  10. 40 CFR 51.307 - New source review.

    Science.gov (United States)

    2010-07-01

    ... and nonair quality environmental impacts of compliance, and the useful life of the source. (d) The... 40 Protection of Environment 2 2010-07-01 2010-07-01 false New source review. 51.307 Section 51... source review. (a) For purposes of new source review of any new major stationary source or major...

  11. 41 CFR 51-2.5 - Committee decision.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Committee decision. 51-2... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 2-COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-2.5 Committee decision. The Committee considers the...

  12. The problematic detection of 51Cr-labelled lymphocytes by autoradiography

    International Nuclear Information System (INIS)

    Rooijen, N. van; Molen, J. van der

    1978-01-01

    The results of a study to investigate the possibilities for autoradiographic detection of 51 Cr-labelled lymphocytes are reported. From the high background in the autoradiographs, caused by 51 Cr eluted from the cells and from the varying labelling results which were obtained it was deduced that the bulk of the 51 Cr was not fixed in the cells after fixation and cell death. Due either to the 51 Cr elution from the cells or to participation of gamma-rays in the autoradiographic results or both, grains were also formed at a distance of several microns from the 51 Cr labelled cells. It is concluded that although 51 Cr may be used as a lymphocyte label in some autoradiographic studies on cell smears, the use of this label for studies in which the tissue localization of labelled cells is intended, seems limited by these disadvantages of the 51 Cr labelling. (U.K.)

  13. 10 CFR 51.32 - Finding of no significant impact.

    Science.gov (United States)

    2010-01-01

    ... assessment is included, the finding need not repeat any of the discussion in the assessment but may... 10 Energy 2 2010-01-01 2010-01-01 false Finding of no significant impact. 51.32 Section 51.32... Section 102(2) Finding of No Significant Impact § 51.32 Finding of no significant impact. (a) A finding of...

  14. 7 CFR 51.2732 - U.S. No. 2 Spanish.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Spanish. 51.2732 Section 51.2732... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2732 U.S. No. 2 Spanish. “U.S. No. 2 Spanish” consists of shelled Spanish type peanut kernels which may be split or broken...

  15. 7 CFR 51.2730 - U.S. No. 1 Spanish.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Spanish. 51.2730 Section 51.2730... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2730 U.S. No. 1 Spanish. “U.S. No. 1 Spanish” consists of shelled Spanish type peanut kernels which are whole and free...

  16. 32 CFR 806b.51 - Privacy and the Web.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Privacy and the Web. 806b.51 Section 806b.51... PROGRAM Disclosing Records to Third Parties § 806b.51 Privacy and the Web. Do not post personal information on publicly accessible DoD web sites unless clearly authorized by law and implementing regulation...

  17. [51Cr]EDTA intestinal permeability in children with cow's milk intolerance

    International Nuclear Information System (INIS)

    Schrander, J.J.; Unsalan-Hooyen, R.W.; Forget, P.P.; Jansen, J.

    1990-01-01

    Making use of [ 51 Cr]EDTA as a permeability marker, we measured intestinal permeability in a group of 20 children with proven cow's milk intolerance (CMI), a group of 17 children with similar complaints where CMI was excluded (sick controls), and a group of 12 control children. [ 51 Cr]EDTA test results (mean +/- SD) were 6.85 +/- 3.64%, 3.42 +/- 0.94%, and 2.61 +/- 0.67% in the group with CMI, the sick control, and the control group, respectively. When compared to both control groups, patients with cow's milk intolerance (CMI) showed a significantly increased small bowel permeability. We conclude that the [ 51 Cr]EDTA test can be helpful for the diagnosis of cow's milk intolerance

  18. Bibliography on Cold Regions Science and Technology. Volume 51, Part 2.

    Science.gov (United States)

    1997-12-01

    1997, eng] 51-2291 PäIsson,O.P. Statistical methods in district heating in Iceland [1997, eng] 51-4259 Palta ,J.P. Molecular mechanisms of...Molecular mechanisms of herbaceous plant cold acclimation. Palta , J.P., et al, [I993,eng) 51-664 Mutations affecting freezing tolerance of plant tissues...51-2692 Molecular mechanisms of herbaceous plant cold acclimation. Palta , J.P, et al, [1993,eng] 51-664 Nitrification and denitrification enzyme

  19. The monoclonal antibody SM5-1 recognizes a fibronectin variant which is widely expressed in melanoma

    Directory of Open Access Journals (Sweden)

    Guo Yajun

    2006-01-01

    Full Text Available Abstract Background Previously we have generated the monoclonal antibody SM5-1 by using a subtractive immunization protocol of human melanoma. This antibody exhibits a high sensitivity for primary melanomas of 99% (248/250 tested and for metastatic melanoma of 96% (146/151 tested in paraffin embedded sections. This reactivity is superior to the one obtained by HMB-45, anti-MelanA or anti-Tyrosinase and is comparable to anti-S100. However, as compared to anti-S100, the antibody SM5-1 is highly specific for melanocytic lesions since 40 different neoplasms were found to be negative for SM5-1 by immunohistochemistry. The antigen recognized by SM5-1 is unknown. Methods In order to characterize the antigen recognized by mAb SM5-1, a cDNA library was constructed from the metastatic human melanoma cell line SMMUpos in the Uni-ZAP lambda phage and screened by mAb SM5-1. The cDNA clones identified by this approach were then sequenced and subsequently analyzed. Results Sequence analysis of nine independent overlapping clones (length 3100–5600 bp represent fibronectin cDNA including the ED-A, but not the ED-B region which are produced by alternative splicing. The 89aa splicing variant of the IIICS region was found in 8/9 clones and the 120aa splicing variant in 1/9 clones, both of which are included in the CS1 region of fibronectin being involved in melanoma cell adhesion and spreading. Conclusion The molecule recognized by SM5-1 is a melanoma associated FN variant expressed by virtually all primary and metastatic melanomas and may play an important role in melanoma formation and progression. This antibody is therefore not only of value in immunohistochemistry, but potentially also for diagnostic imaging and immunotherapy.

  20. 28 CFR 51.55 - Consistency with constitutional and statutory requirements.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Consistency with constitutional and statutory requirements. 51.55 Section 51.55 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... the Attorney General § 51.55 Consistency with constitutional and statutory requirements. (a...

  1. 40 CFR 51.305 - Monitoring for reasonably attributable visibility impairment.

    Science.gov (United States)

    2010-07-01

    ... visibility impairment. 51.305 Section 51.305 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Protection of Visibility § 51.305 Monitoring for reasonably attributable visibility impairment. (a) For the purposes of addressing reasonably attributable visibility impairment, each State containing a mandatory...

  2. Loss of 51chromium, lactate dehydrogenase, and 111indium as indicators of endothelial cell injury

    International Nuclear Information System (INIS)

    Chopra, J.; Joist, J.H.; Webster, R.O.

    1987-01-01

    Injury to endothelial cells appears to be an important initial event in the pathogenesis of many diseases such as acute lung injury, venous and arterial thromboembolism, and atherosclerosis. Different methods for detecting damage to cultured endothelial cells have been described. However, their relative sensitivity as markers of endothelial cell damage has not been adequately determined. We compared the loss of 51 Chromium ( 51 Cr), the cytoplasmic enzyme lactate dehydrogenase (LDH), and 111 Indium ( 111 In) from endothelial cells upon exposure to several injurious agents. Cultured bovine pulmonary artery endothelial cells in confluent monolayers were labeled with 51 Cr or 111 Inoxine and exposed to increasing concentrations of the nonionic detergent, Triton X-100 (0.2 to 1%), hydrogen peroxide (1 to 500 microM), or neutrophils stimulated with phorbol myristate acetate. With all forms of injury, loss of 51 Cr occurred earlier and to a greater extent than LDH loss which in turn was greater than loss of 111 In. Substantial loss of 51 Cr was observed in the absence of appreciable ultrastructural damage to endothelial cell external membranes. The findings may reflect the relative ease with which small molecules such as adenine nucleotides ( 51 Cr-labeled) escape whereas larger molecules such as LDH and proteins binding 111 In are retained intracellularly. Thus, 51 Cr loss appears to be a more sensitive indicator of sublytic endothelial cell injury than either 111 In or LDH release

  3. 32 CFR 310.51 - General.

    Science.gov (United States)

    2010-07-01

    ... PROGRAM Computer Matching Program Procedures § 310.51 General. (a) A computer matching program covers two... action against specific individuals. (2) Performed to support research or statistical projects...

  4. CHARACTERIZATION AND SETTLING TESTS WITH TANK 51H SLURRY SAMPLES HTF-076-081

    International Nuclear Information System (INIS)

    HAY, MICHAEL

    2006-01-01

    increase the settling rate of Tank 51H sludge by adjusting the sludge to a 1.0 M free hydroxide concentration and heating to 60-65 C for four days also showed no improvement in the settling rate. Limited flocculant addition testing has been performed with simulants to try and improve the settling rate and has been documented in a separate memorandum. Testing of additional additives with sludge simulants is being pursued and any found to be successful will be tested with the Tank 51H sludge sample

  5. Caffeine inhibits gene conversion by displacing Rad51 from ssDNA

    Science.gov (United States)

    Tsabar, Michael; Mason, Jennifer M.; Chan, Yuen-Ling; Bishop, Douglas K.; Haber, James E.

    2015-01-01

    Efficient repair of chromosomal double-strand breaks (DSBs) by homologous recombination relies on the formation of a Rad51 recombinase filament that forms on single-stranded DNA (ssDNA) created at DSB ends. This filament facilitates the search for a homologous donor sequence and promotes strand invasion. Recently caffeine treatment has been shown to prevent gene targeting in mammalian cells by increasing non-productive Rad51 interactions between the DSB and random regions of the genome. Here we show that caffeine treatment prevents gene conversion in yeast, independently of its inhibition of the Mec1ATR/Tel1ATM-dependent DNA damage response or caffeine's inhibition of 5′ to 3′ resection of DSB ends. Caffeine treatment results in a dosage-dependent eviction of Rad51 from ssDNA. Gene conversion is impaired even at low concentrations of caffeine, where there is no discernible dismantling of the Rad51 filament. Loss of the Rad51 filament integrity is independent of Srs2's Rad51 filament dismantling activity or Rad51's ATPase activity and does not depend on non-specific Rad51 binding to undamaged double-stranded DNA. Caffeine treatment had similar effects on irradiated HeLa cells, promoting loss of previously assembled Rad51 foci. We conclude that caffeine treatment can disrupt gene conversion by disrupting Rad51 filaments. PMID:26019181

  6. The FKBP51-Glucocorticoid Receptor Balance in Stress-Related Mental Disorders.

    Science.gov (United States)

    Fries, Gabriel R; Gassen, Nils C; Schmidt, Ulrike; Rein, Theo

    2015-01-01

    The immunophilin FK506 binding protein 51 (FKBP51) has emerged as one of the most intensely investigated proteins in stress-related mental disorders. It was originally characterized as Hsp90 cochaperone and part of the receptor-chaperone heterocomplex that governs the activity of steroid receptors. It turned out that the presence of FKBP51 in this heterocomplex leads to diminished activity of the corticosteroid receptors. In particular, based on its inhibitory action on the glucocorticoid receptor (GR), FKBP51 was included in a candidate gene approach to discover gene polymorphisms that might be relevant for the development and treatment of major depression. The discovery that polymorphisms in the gene coding for FKBP51 were linked to the treatment response of depressed patients intensified the research on the role of FKBP51 in stress-related diseases worldwide. It has become evident that FKBP51 is not only a regulator of GR action, but also a GR target. The function of this ultrashort intracellular feedback loop is critically important for cellular and physiological stress regulation as it does not only calibrate the function of GR, but also the levels of FKBP51. Given the pleiotropic functions of FKBP51, its levels might be equally important for mental disorders as GR function and hence for the development of potential FKBP51 drug targets.

  7. 40 CFR 264.51 - Purpose and implementation of contingency plan.

    Science.gov (United States)

    2010-07-01

    ... contingency plan. 264.51 Section 264.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 264.51 Purpose and implementation of contingency plan. (a) Each owner or operator must have a contingency plan for his facility. The contingency...

  8. Astaxanthin down-regulates Rad51 expression via inactivation of AKT kinase to enhance mitomycin C-induced cytotoxicity in human non-small cell lung cancer cells.

    Science.gov (United States)

    Ko, Jen-Chung; Chen, Jyh-Cheng; Wang, Tai-Jing; Zheng, Hao-Yu; Chen, Wen-Ching; Chang, Po-Yuan; Lin, Yun-Wei

    2016-04-01

    Astaxanthin has been demonstrated to exhibit a wide range of beneficial effects, including anti-inflammatory and anti-cancer properties. However, the molecular mechanism of astaxanthin-induced cytotoxicity in non-small cell lung cancer (NSCLC) cells has not been identified. Rad51 plays a central role in homologous recombination, and studies show that chemo-resistant carcinomas exhibit high levels of Rad51 expression. In this study, astaxanthin treatment inhibited cell viability and proliferation of two NSCLC cells, A549 and H1703. Astaxanthin treatment (2.5-20 μM) decreased Rad51 expression and phospho-AKT(Ser473) protein level in a time and dose-dependent manner. Furthermore, expression of constitutively active AKT (AKT-CA) vector rescued the decreased Rad51 mRNA and protein levels in astaxanthin-treated NSCLC cells. Combined treatment with phosphatidylinositol 3-kinase (PI3K) inhibitors (LY294002 or wortmannin) further decreased the Rad51 expression in astaxanthin-exposed A549 and H1703 cells. Knockdown of Rad51 expression by transfection with si-Rad51 RNA or cotreatment with LY294002 further enhanced the cytotoxicity and cell growth inhibition of astaxanthin. Additionally, mitomycin C (MMC) as an anti-tumor antibiotic is widely used in clinical NSCLC chemotherapy. Combination of MMC and astaxanthin synergistically resulted in cytotoxicity and cell growth inhibition in NSCLC cells, accompanied with reduced phospho-AKT(Ser473) level and Rad51 expression. Overexpression of AKT-CA or Flag-tagged Rad51 reversed the astaxanthin and MMC-induced synergistic cytotoxicity. In contrast, pretreatment with LY294002 further decreased the cell viability in astaxanthin and MMC co-treated cells. In conclusion, astaxanthin enhances MMC-induced cytotoxicity by decreasing Rad51 expression and AKT activation. These findings may provide rationale to combine astaxanthin with MMC for the treatment of NSCLC. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. 7 CFR 51.1179 - Method of juice extraction.

    Science.gov (United States)

    2010-01-01

    ... STANDARDS) United States Standards for Grades of Florida Oranges and Tangelos Standards for Internal Quality... 7 Agriculture 2 2010-01-01 2010-01-01 false Method of juice extraction. 51.1179 Section 51.1179 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...

  10. 40 CFR 265.51 - Purpose and implementation of contingency plan.

    Science.gov (United States)

    2010-07-01

    ... contingency plan. 265.51 Section 265.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED..., STORAGE, AND DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.51 Purpose and implementation of contingency plan. (a) Each owner or operator must have a contingency plan for his facility. The...

  11. 7 CFR 51.490 - Decay.

    Science.gov (United States)

    2010-01-01

    ... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Cantaloups 1 Definitions § 51.490 Decay. Decay means breakdown, disintegration or...

  12. Simultaneous administration of lactulose and 51Cr-ethylenediaminetetraacetic acid

    International Nuclear Information System (INIS)

    Jenkins, A.P.; Nukajam, W.S.; Menzies, S.; Creamer, B.

    1992-01-01

    In normal adults intestinal permeation of ingested 51 Cr-ethylenediaminetetraacetic acid (EDTA) is greater than that of lactulose. This difference is abolished in patients with ileostomies, suggesting that it results from colonic permeation of 51 Cr-EDTA, which, unlike lactulose, resists bacterial degradation. To investigate the effect of an increase in colonic permeability on absorption of the two molecules, lactulose and 51 Cr-EDTA were given orally in isosmolar solution to 11 patients with colitis, and their 24-h urinary excretion measured. By comparison the effect of an increase in small-intestinal permeability induced by ingestion of a hyperosmolar solution was measured in 10 healthy adults. Hyperosmolar stress increased the 24-h urinary excretion of 51 Cr-EDTA above the normal mean + 2 standard deviations in all 10 healthy subjects, and in all of these excretion of lactulose was also increased. In contrast, although seven colitics had a urinary excretion of 51 Cr-EDTA above the normal mean + 2 SD, in only two of these patients was recovery of lactulose increased. This suggests that simultaneous administration of lactulose and 51 Cr-EDTA may enable permeability changes affecting the colon alone to be distinguished from those involving the small intestine. 15 refs., 1 fig., 5 tabs

  13. 10 CFR 51.95 - Postconstruction environmental impact statements.

    Science.gov (United States)

    2010-01-01

    ... NRC staff will prepare a supplement to the final environmental impact statement on the construction... 10 Energy 2 2010-01-01 2010-01-01 false Postconstruction environmental impact statements. 51.95... Implementing Section 102(2) Final Environmental Impact Statements-Production and Utilization Facilities § 51.95...

  14. 41 CFR 109-26.501-51 - Used vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Used vehicles. 109-26.501-51 Section 109-26.501-51 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26...

  15. 41 CFR 51-6.4 - Military resale commodities.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Military resale commodities. 51-6.4 Section 51-6.4 Public Contracts and Property Management Other Provisions Relating to... stores, Armed Forces exchanges and like activities of other Government departments and agencies) shall...

  16. 41 CFR 51-5.2 - Mandatory source requirement.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Mandatory source requirement. 51-5.2 Section 51-5.2 Public Contracts and Property Management Other Provisions Relating to... such as the Defense Logistics Agency and the General Services Administration, and certain commercial...

  17. Food Fingerprinting: Characterization of the Ecuadorean Type CCN-51 of Theobroma cacao L. Using Microsatellite Markers.

    Science.gov (United States)

    Herrmann, Luise; Felbinger, Christine; Haase, Ilka; Rudolph, Barbara; Biermann, Bernhard; Fischer, Markus

    2015-05-13

    The cocoa type "Colección Castro Naranjal 51" (CCN-51) is known for its resistance to specific climate conditions and its high yield, but it shows a weaker flavor profile and therefore is marketed as bulk cocoa. In a previous study, the two cocoa types Arriba and CCN-51 could easily be distinguished, but differences among the CCN-51 samples were observed. This was unexpected, as CCN-51 is reported to be a clone. To confirm whether CCN-51 is a pure clone, 10 simple sequence repeats (SSR) located on the nuclear genome were used to analyze various CCN-51 samples in comparison to the cocoa varieties Arriba and Criollo. As expected, there are differences in the SSR pattern among CCN-51, Arriba, and Criollo, but a variability within the CCN-51 sample set was detected as well. The previously described sequence variation in the chloroplast genome was confirmed by a variability in the microsatellite loci of the nuclear genome for a comprehensive cultivar collection of CCN-51 of both bean and leaf samples. In summary, beneath somaclonal variation, misidentification of plant collections and also sexual reproduction of CCN-51 can be suggested.

  18. R&D Proposal RD51 Extension Beyond 2018

    CERN Document Server

    Dalla Torre, S; Ropelewski, L; Titov, M

    2018-01-01

    The RD51 Collaboration, in charge of the development and dissemination of MicroPattern Gaseous Detectors (MPGD) since 2008, proposes to extend its ac-tivity, after 2018, for a further five-year term. Since the RD51 initial years, the community of MPGD developers and users has grown considerably. It is reflected by the many MPGD-based applications in high energy and nuclear physics experi-ments as well as in other basic and applied-research fields. They rely on the parallel progress of detector concepts and associated technologies. The cultural, infrastruc-ture and networking support offered by RD51 has been essential in this process. The rich portfolio of MPGD projects, under constant expansion, is accompanied by novel ideas on further developments and applications. The proposed next term of RD51 activities aims at bringing a number of de-tector concepts to maturity, initiating new projects and continuing the support to the community. Among leading proposed projects are ultrafast, high-rate MPGDs; discharg...

  19. Characterization of Tank 51 Sludge Slurry Samples (HTF-51-17-67, -68, -69, -74, -75, and -76) in Support of Sludge Batch 10 Processing

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Reboul, S. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-11-09

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) Engineering (SRR-E) to provide sample characterization and analyses of Tank 51 sludge samples in support of Sludge Batch (SB) 10. The six Tank 51 sludge samples were sampled and delivered to SRNL in August of 2017. These six Tank 51 sludge samples, after undergoing physical characterizations which included rheology, weight percent total solid, dissolved solids and density measurements, were combined into one composite Tank 51 sample and analyzed for corrosion controls analytes, select radionuclides, chemical elements, density and weight percent total solids.

  20. Roles of Rad51 protein in homologous recombination in mammalian cells: relation with repair, replication and cell cycle

    International Nuclear Information System (INIS)

    Lambert, S.

    2001-01-01

    Homologous recombination (HR) is a fundamental process, allowing a faithful repair. In mammalian, MmRAD51, which is the homologue of Saccharomyces cerevisiae ScRAD51 key protein for HR, is an essential gene. This work is based on the characterisation of viable hyper and hypo-recombinant cell lines specifically affected in the Rad51 pathway. By expressing wild type and dominant negative forms of MmRad51, we demonstrated that Rad51 pathway participates to the repair by HR to induced DNA damages. However, inhibition of the Rad 51 pathway does not affect cell viability, spontaneously or after irradiation, whereas, radiation induced HR is inhibited. In the presence of DNA damages during late S and G2/M phase, inhibition of Rad51 pathway induced chromosomal aberrations, leading to a transient arrest in mitosis. This arrest is associated with an increased of cell death. However, a fraction of cells can escape from this transient arrest by forming tetraploid cells, associated with an absence of chromalid separation. Thus, in response to impaired Rad51 pathway, mitotic checkpoints seems to play an essential role. In line with this, we showed that the essential function of Rad51 is p53-dependent, which is in agreement with the role of p53 in tetraploidy inhibition. Our results suggest that the Rad51 protein could participate to the control of mitotic checkpoints and thus to the maintenance of genetic stability. This function could involve other Rad51 partners such as the tumour suppressors BRCA1, BRCA2 and p53. (author) [fr

  1. 45 CFR 260.51 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-10-01

    ... of Domestic Violence? § 260.51 What definitions apply to this subpart? Family Violence Option (or FVO... 45 Public Welfare 2 2010-10-01 2010-10-01 false What definitions apply to this subpart? 260.51 Section 260.51 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE...

  2. 9 CFR 145.51 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... purposes of meat or egg production and competitive showing. Game birds. Domesticated fowl such as pheasants... Waterfowl, Exhibition Poultry, and Game Bird Breeding Flocks and Products § 145.51 Definitions. Except where...

  3. 7 CFR 51.2555 - General.

    Science.gov (United States)

    2010-01-01

    ... Standards for Grades of Shelled Pistachio Nuts § 51.2555 General. (a) Compliance with the provisions of.... (b) These standards are applicable to raw, roasted, salted or salted/roasted pistachio kernels. [55...

  4. 7 CFR 51.1447 - Fairly uniform in color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly uniform in color. 51.1447 Section 51.1447... color. Fairly uniform in color means that 90 percent or more of the kernels in the lot have skin color within the range of one or two color classifications. ...

  5. 7 CFR 51.1407 - Fairly uniform in color.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fairly uniform in color. 51.1407 Section 51.1407 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... in color. Fairly uniform in color means that the shells do not show sufficient variation in color to...

  6. 28 CFR 550.51 - Drug abuse education course.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Drug abuse education course. 550.51... DRUG PROGRAMS Drug Abuse Treatment Program § 550.51 Drug abuse education course. (a) Purpose of the drug abuse education course. All institutions provide a drug abuse education course to: (1) Inform...

  7. 36 CFR 51.92 - What are standard proformas?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false What are standard proformas? 51.92 Section 51.92 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE... narrative description must include, but is not limited to, identification of the loan's collateral after...

  8. 7 CFR 51.481 - Very good internal quality.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Very good internal quality. 51.481 Section 51.481 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... quality. Very good internal quality means that the combined juice from the edible portion of a sample of...

  9. Analiza igre branilcev v conski obrambi 5:1 pri rokometu

    OpenAIRE

    Kozole, Rok

    2017-01-01

    V diplomski nalogi je predstavljena analiza igre branilcev v conski obrambi 5:1 pri rokometu. Obrambna formacija 5:1 je po obrambi 6:0 druga najpogosteje uporabljena obrambna formacija, katere se poslužujejo tako ekipe iz vrhunskega rokometa kot tudi ekipe, ki tekmujejo v ligah nižje kakovosti. V skladu s hitrim razvojem rokometne igre se je razvijala tudi obramba 5:1. Obrambna formacija 5:1 se pri mlajših rokometaših uporablja tudi kot prehodna obramba oz. temelj za prehod iz bolj globokih (...

  10. 24 CFR 51.200 - Purpose.

    Science.gov (United States)

    2010-04-01

    ... Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.200 Purpose. The purpose of this... store, handle, or process hazardous substances; (b) Alert those responsible for the siting of HUD...

  11. PEGASUS User's Guide. 5.1c

    Science.gov (United States)

    Suhs, Norman E.; Dietz, William E.; Rogers, Stuart E.; Nash, Steven M.; Onufer, Jeffrey T.

    2000-01-01

    PEGASUS 5.1 is the latest version of the PEGASUS series of mesh interpolation codes. It is a fully three-dimensional code. The main purpose for the development of this latest version was to significantly decrease the number of user inputs required and to allow for easier operation of the code. This guide is to be used with the user's manual for version 4 of PEGASUS. A basic description of methods used in both versions is described in the Version 4 manual. A complete list of all user inputs used in version 5.1 is given in this guide.

  12. Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament.

    Science.gov (United States)

    Ma, Chu Jian; Gibb, Bryan; Kwon, YoungHo; Sung, Patrick; Greene, Eric C

    2017-01-25

    Homologous recombination (HR) is a crucial pathway for double-stranded DNA break (DSB) repair. During the early stages of HR, the newly generated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly bound by replication protein A (RPA). RPA is then replaced by the DNA recombinase Rad51, which forms extended helical filaments on the ssDNA. The resulting nucleoprotein filament, known as the presynaptic complex, is responsible for pairing the ssDNA with homologous double-stranded DNA (dsDNA), which serves as the template to guide DSB repair. Here, we use single-molecule imaging to visualize the interplay between human RPA (hRPA) and human RAD51 during presynaptic complex assembly and disassembly. We demonstrate that ssDNA-bound hRPA can undergo facilitated exchange, enabling hRPA to undergo rapid exchange between free and ssDNA-bound states only when free hRPA is present in solution. Our results also indicate that the presence of free hRPA inhibits RAD51 filament nucleation, but has a lesser impact upon filament elongation. This finding suggests that hRPA exerts important regulatory influence over RAD51 and may in turn affect the properties of the assembled RAD51 filament. These experiments provide an important basis for further investigations into the regulation of human presynaptic complex assembly. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  13. 47 CFR 51.505 - Forward-looking economic cost.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Forward-looking economic cost. 51.505 Section... (CONTINUED) INTERCONNECTION Pricing of Elements § 51.505 Forward-looking economic cost. (a) In general. The forward-looking economic cost of an element equals the sum of: (1) The total element long-run incremental...

  14. 40 CFR 69.51 - Motor vehicle diesel fuel.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Motor vehicle diesel fuel. 69.51... (CONTINUED) SPECIAL EXEMPTIONS FROM REQUIREMENTS OF THE CLEAN AIR ACT Alaska § 69.51 Motor vehicle diesel... motor vehicle diesel fuel standards and dye provisions under 40 CFR 80.520 and associated requirements...

  15. 10 CFR 51.40 - Consultation with NRC staff.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Consultation with NRC staff. 51.40 Section 51.40 Energy....40 Consultation with NRC staff. (a) A prospective applicant or petitioner for rulemaking is encouraged to confer with NRC staff as early as possible in its planning process before submitting...

  16. 40 CFR 51.366 - Data analysis and reporting.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Data analysis and reporting. 51.366... Requirements § 51.366 Data analysis and reporting. Data analysis and reporting are required to allow for..., including the results of an analysis of the registration data base; (ii) The percentage of motorist...

  17. 12 CFR 208.51 - Real estate lending standards.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

  18. 41 CFR 51-9.102-1 - Specific exemptions.

    Science.gov (United States)

    2010-07-01

    ...-General Policy § 51-9.102-1 Specific exemptions. Systems of records maintained by the Committee which have... part. An individual shall have access to all exempted records containing information about him under procedures outlined in Subpart 51-9.3 of this part. Upon request, an individual shall receive an accounting...

  19. 7 CFR 51.2296 - Three-fourths half kernel.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Three-fourths half kernel. 51.2296 Section 51.2296 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...-fourths half kernel. Three-fourths half kernel means a portion of a half of a kernel which has more than...

  20. RAD51 interconnects between DNA replication, DNA repair and immunity.

    Science.gov (United States)

    Bhattacharya, Souparno; Srinivasan, Kalayarasan; Abdisalaam, Salim; Su, Fengtao; Raj, Prithvi; Dozmorov, Igor; Mishra, Ritu; Wakeland, Edward K; Ghose, Subroto; Mukherjee, Shibani; Asaithamby, Aroumougame

    2017-05-05

    RAD51, a multifunctional protein, plays a central role in DNA replication and homologous recombination repair, and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cytoplasm, triggering a STING-mediated innate immune response after replication stress and DNA damage. In the absence of RAD51, the unprotected newly replicated genome is degraded by the exonuclease activity of MRE11, and the fragmented nascent DNA accumulates in the cytosol, initiating an innate immune response. Our data suggest that in addition to playing roles in homologous recombination-mediated DNA double-strand break repair and replication fork processing, RAD51 is also implicated in the suppression of innate immunity. Thus, our study reveals a previously uncharacterized role of RAD51 in initiating immune signaling, placing it at the hub of new interconnections between DNA replication, DNA repair, and immunity. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  1. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  2. Germline RAD51B truncating mutation in a family with cutaneous melanoma

    DEFF Research Database (Denmark)

    Wadt, Karin A W; Aoude, Lauren G; Golmard, Lisa

    2015-01-01

    Known melanoma predisposition genes only account for around 40% of high-density melanoma families. Other rare mutations are likely to play a role in melanoma predisposition. RAD51B plays an important role in DNA repair through homologous recombination, and inactivation of RAD51B has been implicated...... in tumorigenesis. Thus RAD51B is a good candidate melanoma susceptibility gene, and previously, a germline splicing mutation in RAD51B has been identified in a family with early-onset breast cancer. In order to find genetic variants associated with melanoma predisposition, whole-exome sequencing was carried out...... on blood samples from a three-case cutaneous melanoma family. We identified a novel germline RAD51B nonsense mutation, and we demonstrate reduced expression of RAD51B in melanoma cells indicating inactivation of RAD51B. This is only the second report of a germline truncating RAD51B mutation. While...

  3. TH-EF-207A-02: Imaging Pancreatic Î{sup 2}-Cell Function with 51/52Mn-PET

    Energy Technology Data Exchange (ETDEWEB)

    Graves, S; Hernandez, R; England, C; Valdovinos, H; Jeffery, J; Barnhart, T; Cai, W; Nickles, R [University of Wisconsin, Madison, WI (United States)

    2016-06-15

    Purpose: To image β-cells noninvasively using radio-manganese PET and to develop efficient small cyclotron production of {sup 51}Mn (t1/2=46m, β{sup +}=97%) and {sup 52}Mn (t1/2=5.6d, β{sup +}=29%). Methods: {sup 51}Mn and {sup 52}Mn were produced by 16 MeV proton irradiation (GE PETtrace) of electrodeposited {sup 54}Fe on silver and Cr metal pressed into a silver disc, respectively. {sup 51}Mn was radiochemically isolated from target material by anion exchange chromatography and {sup 52}Mn was isolated by ethanolic anion exchange trap-and-release. A final injectable product of {sup 51}Mn{sup 2+} or {sup 52}Mn{sup 2+} was obtained in 0.01M pH 6.0 NaOAc. To assess pancreatic uptake, fasted ICR mice were administered and intravenous bolus or infusion of {sup 52}Mn{sup 2+}. Additionally, to demonstrate the correlation between β-cell function and {sup 52}Mn{sup 2+} pancreatic uptake, prior to tracer administration groups of ICR mice were administered glibenclamide (5mg/kg) and diazoxide (20 mg/kg) as an insulin release stimulator and blocker, respectively. To validate PET ROI quantification, ex vivo biodistribtution studies were conducted on each subject after the final imaging time-point. Results: Dynamic PET data using a left atrium ROI revealed that {sup 52}Mn{sup 2+} cleared from the blood with a 10 second half-life. Significant uptake was seen in the pancreas (approximately 20% ID/g, SUVmean= 5.5), liver, kidneys, intestine, heart, and thyroid. Pancreatic uptake was found to be highly sensitive to volatile anesthesia administration (p=0.0002), insulin release stimulation by glibenclamide (p=0.017), and by insulin release inhibition by diazoxide (p=0.046). Excellent agreement was found between in vivo PET ROI quantification and ex vivo biodistribution measurements. Conclusion: This work demonstrates the feasibility of using radiomanganese-PET for measuring functional β-cell mass in vivo. The decay characteristics and dosimetric properties of {sup 51}Mn are

  4. 7 CFR 51.2560 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... Standards for Grades of Shelled Pistachio Nuts § 51.2560 Definitions. (a) Well dried means the kernel is... than pistachio kernels. No allowable tolerances for metal or glass. (d) Whole kernel means 3/4 of a...

  5. 41 CFR 51-9.202 - Accounting of disclosures.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Accounting of disclosures... RULES 9.2-Disclosure of Records § 51-9.202 Accounting of disclosures. (a) Except for disclosures made pursuant to paragraphs (a) and (b) of § 51-9.201 of this part, an accurate accounting of each disclosure...

  6. 41 CFR 51-2.7 - Fair market price.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Fair market price. 51-2.7... WHO ARE BLIND OR SEVERELY DISABLED § 51-2.7 Fair market price. (a) The Committee is responsible for determining fair market prices, and changes thereto, for commodities and services on the Procurement List. The...

  7. Rheology of Savannah River site tank 42 and tank 51 HLW radioactive sludges

    International Nuclear Information System (INIS)

    Ha, B.C.; Bibler, N.E.

    1996-01-01

    Knowledge of the rheology of the radioactive sludge slurries at the Savannah River Site (SRS) is necessary in order to ensure that they can be retrieved from waste tanks and processed for final disposal. The high activity radioactive wastes stored as caustic slurries at SRS result from the neutralization of acid waste generated from production of nuclear defense materials. During storage, the wastes separate into a supernate layer and a sludge layer. In the Defense Waste Processing Facility (DWPF) at SRS, the radionuclides from the sludge and supernate will be immobilized into borosilicate glass for long term storage and eventual disposal. Before transferring the waste from a storage tank to the DWPF, a portion of the aluminum in the waste sludge will be dissolved and the sludge will be extensively washed to remove sodium. Tank 51 and Tank 42 radioactive sludges represent the first batch of HLW sludge to be processed in the DWPF. This paper presents results of rheology measurements of Tank 51 and Tank 42 at various solids concentrations. The rheologies of Tank 51 and Tank 42 radioactive slurries were measured remotely in the Shielded Cells Operations (SCO) at the Savannah River Technology Center (SRTC) using a modified Haake Rotovisco RV-12 with an M150 measuring drive unit and TI sensor system. Rheological properties of the Tank 51 and Tank 42 radioactive sludges were measured as a function of weight percent solids. The weight percent solids of Tank 42 sludge was 27, as received. Tank 51 sludge had already been washed. The weight percent solids were adjusted by dilution with water or by concentration through drying. At 12, 15, and 18 weight percent solids, the yield stresses of Tank 51 sludge were 5, 11, and 14 dynes/cm2, respectively. The apparent viscosities were 6, 10, and 12 centipoises at 300 sec-1 shear rate, respectively

  8. 7 CFR 51.2540 - General.

    Science.gov (United States)

    2010-01-01

    ... Standards for Grades of Pistachio Nuts in the Shell § 51.2540 General. (a) Compliance with the provisions of.... (b) These standards are applicable to pistachio nuts in the shell which may be in a natural, dyed...

  9. Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

    Energy Technology Data Exchange (ETDEWEB)

    Strushkevich, Natallia; Usanov, Sergey A.; Park, Hee-Won (Toronto); (IBC-Belarus)

    2010-09-22

    The obligatory step in sterol biosynthesis in eukaryotes is demethylation of sterol precursors at the C14-position, which is catalyzed by CYP51 (sterol 14-alpha demethylase) in three sequential reactions. In mammals, the final product of the pathway is cholesterol, while important intermediates, meiosis-activating sterols, are produced by CYP51. Three crystal structures of human CYP51, ligand-free and complexed with antifungal drugs ketoconazole and econazole, were determined, allowing analysis of the molecular basis for functional conservation within the CYP51 family. Azole binding occurs mostly through hydrophobic interactions with conservative residues of the active site. The substantial conformational changes in the B{prime} helix and F-G loop regions are induced upon ligand binding, consistent with the membrane nature of the protein and its substrate. The access channel is typical for mammalian sterol-metabolizing P450 enzymes, but is different from that observed in Mycobacterium tuberculosis CYP51. Comparison of the azole-bound structures provides insight into the relative binding affinities of human and bacterial P450 enzymes to ketoconazole and fluconazole, which can be useful for the rational design of antifungal compounds and specific modulators of human CYP51.

  10. Rheology of Savannah River Site Tank 51 HLW radioactive sludge

    International Nuclear Information System (INIS)

    Ha, B.C.

    1993-01-01

    Savannah River Site (SRS) Tank 51 HLW radioactive sludge represents a major portion of the first batch of sludge to be vitrified in the Defense Waste Processing Facility (DWPF) at SRS. The rheological properties of Tank 51 sludge will determine if the waste sludge can be pumped by the current DWPF process cell pump design and the homogeneity of melter feed slurries. The rheological properties of Tank 51 sludge and sludge/frit slurries at various solids concentrations were measured remotely in the Shielded Cells Operations (SCO) at the Savannah River Technology Center (SRTC) using a modified Haake Rotovisco viscometer system. Rheological properties of Tank 51 radioactive sludge/Frit 202 slurries increased drastically when the solids content was above 41 wt %. The yield stresses of Tank 51 sludge and sludge/frit slurries fall within the limits of the DWPF equipment design basis. The apparent viscosities also fall within the DWPF design basis for sludge consistency. All the results indicate that Tank 51 waste sludge and sludge/frit slurries are pumpable throughout the DWPF processes based on the current process cell pump design, and should produce homogeneous melter feed slurries

  11. Immune Responses and Protection against Experimental Brucella suis biovar 1 Challenge in Non-vaccinated or RB51-Vaccinated Cattle

    Science.gov (United States)

    Twenty Hereford heifers, approximately 9 months of age, were vaccinated with saline (control) or 2 x 10**10 CFU of Brucella abortus strain RB51 (RB51) vaccine. Immunologic responses after inoculation demonstrated significantly greater (P<0.05) antibody and proliferative responses to RB51 antigens i...

  12. Spectral line survey toward the spiral arm of M51 in the 3 and 2 mm bands

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Yoshimasa; Sakai, Nami; Yamamoto, Satoshi [Department of Physics, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Sorai, Kazuo, E-mail: nabe@taurus.phys.s.u-tokyo.ac.jp [Department of Physics/Department of Cosmoscience, Hokkaido University, Kita 10, Nishi 8, Kita-ku, Sapporo, Hokkaido 060-0810 (Japan)

    2014-06-10

    We have conducted a spectral line survey in the 3 and 2 mm bands toward two positions in a spiral arm of M51 (NGC 5194) with the Institut de Radioastronomie Millimétrique 30 m telescope. In this survey, we have identified 13 molecular species, including CN, CCH, N{sub 2}H{sup +}, HNCO, and CH{sub 3}OH. Furthermore, six isotopologues of the major species have been detected. On the other hand, SiO, HC{sub 3}N, CH{sub 3}CN, and deuterated species such as DCN and DCO{sup +} were not detected. The deuterium fractionation ratios are evaluated to be less than 0.8% and 1.2% for DCN/HCN and DCO{sup +}/HCO{sup +}, respectively. By comparing the results of the two positions with different star formation activities, we have found that the observed chemical compositions do not strongly depend on star formation activities. They seem to reflect a chemical composition averaged over the 1 kpc scale region including many giant molecular clouds. Among the detected molecules CN, CCH, and CH{sub 3}OH are found to be abundant. High abundances of CN and CCH are consistent with the above picture of a widespread distribution of molecules because they can be produced by photodissociation. On the other hand, it seems likely that CH{sub 3}OH is liberated in the gas phase by shocks associated with large-scale phenomena such as cloud-cloud collisions and/or by nonthermal desorption processes such as photoevaporation due to cosmic-ray-induced UV photons. The present result demonstrates a characteristic chemical composition of a giant molecular cloud complex in the spiral arm, which can be used as a standard reference for studying chemistry in active galactic nuclei and starbursts.

  13. The immunological response of RB51 vaccinated buffalo calves ...

    African Journals Online (AJOL)

    radosova

    2011-09-07

    Sep 7, 2011 ... Consequently, cattle vaccinated with RB51 do not sero- convert on conventional .... 1997), iELISAs using a 5% optical density heat-killed whole RB51 .... In: Yousef MK (Ed.), Stress Physiology in Livestock,. Ungulates, vol. 2.

  14. 22 CFR 51.61 - Denial of passports to certain convicted drug traffickers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Denial of passports to certain convicted drug... Denial, Revocation, and Restriction of Passports § 51.61 Denial of passports to certain convicted drug... felony conviction for a Federal or state drug offense, if the individual used a U.S. passport or...

  15. 10 CFR 51.85 - Draft environmental impact statement-rulemaking.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Draft environmental impact statement-rulemaking. 51.85... Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.85 Draft environmental impact... Commission has determined to prepare an environmental impact statement. ...

  16. 47 CFR 51.701 - Scope of transport and termination pricing rules.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Scope of transport and termination pricing rules. 51.701 Section 51.701 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... Telecommunications Traffic § 51.701 Scope of transport and termination pricing rules. (a) The provisions of this...

  17. 7 CFR 51.1260 - General.

    Science.gov (United States)

    2010-01-01

    ... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Summer and Fall Pears 1 General § 51.1260 General. These standards apply to varieties such as Bartlett, Hardy and other similar varieties. Grades ...

  18. 15 CFR 5.1 - Purpose.

    Science.gov (United States)

    2010-01-01

    ... includes vending machines). ... Foreign Trade Office of the Secretary of Commerce OPERATION OF VENDING STANDS § 5.1 Purpose. This part... the Randolph-Sheppard Vending Stand Act (49 Stat. 1559, as amended by the act of August 3, 1954, 68...

  19. 51Cr-bleomycin, a new oncophilic radiopharmaceutical. Pt. 2

    International Nuclear Information System (INIS)

    Liniecki, J.; Brykalski, D.; Pertynski, T.; Rembelska, M.J.; Durski, K.; Fajndt, S.

    1982-01-01

    51 Cr-bleomycin was used for the scintigraphic detection of tumours and the assessment of the spread of the disease in 20 patients with various malignances: 7 with Hodgkin's lymphoma, 5 with other malignant lymphomas, 4 cases of cervix carcinoma and 4 other tumours. The scintigraphy was performed using a Toshiba GC 401 gamma camera coupled to an MDSI computer Trinary. Active foci were scored using a semiquantitative scale of 0 to 5. Results of these studies were compared with those of tests similarity carried out with 57 Co-bleomycin (in 9 of the cases) and 67 Ga-citrate (11 cases); they demonstrated that the properties of 51 Cr-bleomycin for scintigraphic detection of neoplastic foci are similar to those of 57 Co-bleomycin. (orig.) [de

  20. Prolonged exposure to particulate chromate inhibits RAD51 nuclear import mediator proteins.

    Science.gov (United States)

    Browning, Cynthia L; Wise, John Pierce

    2017-09-15

    Particulate hexavalent chromium (Cr(VI)) is a human lung carcinogen and a human health concern. The induction of structural chromosome instability is considered to be a driving mechanism of Cr(VI)-induced carcinogenesis. Homologous recombination repair protects against Cr(VI)-induced chromosome damage, due to its highly accurate repair of Cr(VI)-induced DNA double strand breaks. However, recent studies demonstrate Cr(VI) inhibits homologous recombination repair through the misregulation of RAD51. RAD51 is an essential protein in HR repair that facilitates the search for a homologous sequence. Recent studies show prolonged Cr(VI) exposure prevents proper RAD51 subcellular localization, causing it to accumulate in the cytoplasm. Since nuclear import of RAD51 is crucial to its function, this study investigated the effect of Cr(VI) on the RAD51 nuclear import mediators, RAD51C and BRCA2. We show acute (24h) Cr(VI) exposure induces the proper localization of RAD51C and BRCA2. In contrast, prolonged (120h) exposure increased the cytoplasmic localization of both proteins, although RAD51C localization was more severely impaired. These results correlate temporally with the previously reported Cr(VI)-induced RAD51 cytoplasmic accumulation. In addition, we found Cr(VI) does not inhibit interaction between RAD51 and its nuclear import mediators. Altogether, our results suggest prolonged Cr(VI) exposure inhibits the nuclear import of RAD51C, and to a lesser extent, BRCA2, which results in the cytoplasmic accumulation of RAD51. Cr(VI)-induced inhibition of nuclear import may play a key role in its carcinogenic mechanism since the nuclear import of many tumor suppressor proteins and DNA repair proteins is crucial to their function. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. A general Euclidean connection for so(n,m) lie algebra and the algebraic approach to scattering

    International Nuclear Information System (INIS)

    Ionescu, R.A.

    1994-11-01

    We obtain a general Euclidean connection for so(n,m). This Euclidean connection allows an algebraic derivation of the S matrix and it reduces to the known one in suitable circumstances. (author). 8 refs

  2. 40 CFR 51.241 - Nonattainment areas for carbon monoxide and ozone.

    Science.gov (United States)

    2010-07-01

    ... Intergovernmental Consultation Agency Designation § 51.241 Nonattainment areas for carbon monoxide and ozone. (a... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Nonattainment areas for carbon monoxide and ozone. 51.241 Section 51.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  3. Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation

    Science.gov (United States)

    Dobson, Rachel; Stockdale, Christopher; Lapsley, Craig; Wilkes, Jonathan; McCulloch, Richard

    2011-01-01

    Homologous recombination in Trypanosoma brucei is used for moving variant surface glycoprotein (VSG) genes into expression sites during immune evasion by antigenic variation. A major route for such VSG switching is gene conversion reactions in which RAD51, a universally conserved recombinase, catalyses homology-directed strand exchange. In any eukaryote, RAD51-directed strand exchange in vivo is mediated by further factors, including RAD51-related proteins termed Rad51 paralogues. These appear to be ubiquitously conserved, although their detailed roles in recombination remain unclear. In T. brucei, four putative RAD51 paralogue genes have been identified by sequence homology. Here we show that all four RAD51 paralogues act in DNA repair, recombination and RAD51 subnuclear dynamics, though not equivalently, while mutation of only one RAD51 paralogue gene significantly impedes VSG switching. We also show that the T. brucei RAD51 paralogues interact, and that the complexes they form may explain the distinct phenotypes of the mutants as well as observed expression interdependency. Finally, we document the Rad51 paralogues that are encoded by a wide range of protists, demonstrating that the Rad51 paralogue repertoire in T. brucei is unusually large among microbial eukaryotes and that one member of the protein family corresponds with a key, conserved eukaryotic Rad51 paralogue. PMID:21615552

  4. Measurement of intestinal permeability using 51Cr-EDTA

    International Nuclear Information System (INIS)

    Peled, Y.; Watz, C.; Gilat, T.

    1985-01-01

    Intestinal permeability tests are a new class of tests of which the 51 Cr-EDTA seemed the easiest to perform. The authors have evaluated the 8- and 24-h urinary excretion of ingested 51 Cr-EDTA in 38 subjects. Twenty-seven patients with diseases not affecting the integrity of the small bowel served as controls. The test group consisted of two patients with celiac, six with Crohn's disease, and three with ulcerative colitis. Nineteen (70.37%) of the control patients had an abnormal test (more than 2.6% in 24 h). The patients with ulcerative colitis had normal excretion (mean 1.95% in 24 h). The patients with celiac disease had an elevated excretion (mean 3.62% in 24 h) and five out of six patients with Crohn's disease also had an increased excretion (mean 6.2% in 24 h). The elevated 51 Cr-EDTA excretion in the control patients casts serious doubts on the validity of the test. Possible causes for abnormal excretion in the controls include various medications used by the patients as well as changes in the chromatographic mobility of 51 Cr-EDTA, demonstrated after incubation with gastric juice

  5. 7 CFR 51.313 - Overripe.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.313 Overripe. “Overripe” means apples which have progressed...

  6. 7 CFR 51.320 - Diameter.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.320 Diameter. When measuring for minimum size, “diameter...

  7. 7 CFR 51.349 - Overripe.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples for Processing Definitions § 51.349 Overripe. Overripe means apples which are...

  8. 7 CFR 51.1300 - General.

    Science.gov (United States)

    2010-01-01

    ... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Winter Pears 1 General § 51.1300 General. These standards apply to varieties such as Anjou, Bosc, Winter Nelis, Comice, Flemish Beauty and other similar varieties. Grades ...

  9. 7 CFR 51.2339 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Kiwifruit § 51.2339 Definitions. Similar varietal characteristics means the fruit in...

  10. 48 CFR 51.201 - Policy.

    Science.gov (United States)

    2010-10-01

    ... GOVERNMENT SOURCES BY CONTRACTORS Contractor Use of Interagency Fleet Management System (IFMS) 51.201 Policy... contractors to obtain, for official purposes only, interagency fleet management system (IFMS) vehicles and... instance. (c) Government contractors shall not be authorized to obtain interagency fleet management system...

  11. 28 CFR 51.62 - Enforcement by the Attorney General.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Enforcement by the Attorney General. 51.62 Section 51.62 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE... Attorney General. (a) The Attorney General is authorized to bring civil actions for appropriate relief...

  12. 10 CFR 51.91 - Final environmental impact statement-contents.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Final environmental impact statement-contents. 51.91... Implementing Section 102(2) Final Environmental Impact Statements-General Requirements § 51.91 Final environmental impact statement—contents. (a)(1) The final environmental impact statement will include responses...

  13. Lorentz violation bounds from torsion trace fermion sector and galaxy M51 data and chiral dynamos

    Energy Technology Data Exchange (ETDEWEB)

    Garcia de Andrade, L.C. [IF-UERJ, Departamento de Fisica Teorica, Rio de Janeiro, RJ (Brazil)

    2017-06-15

    Earlier we have computed a Lorentz violation (LV) bound for torsion terms via galactic dynamos and found bounds similar to the one obtained by Kostelecky et al. (Phys Rev Lett 100:111102, 2008) which is of the order of 10{sup -31} GeV. Their result was found making use of the axial torsion vector in terms of Dirac spinors and minimal torsion coupling in flat space-time of fermions. In this paper, a torsion dynamo equation obtained using the variation of the torsion trace and galaxy M51 data of 500 pc are used to place an upper bound of 10{sup -26} GeV in LV, which agrees with the one by Kostelecky and his group using an astrophysical framework background. Their lowest bound was obtained in earth laboratory using dual masers. One of the purposes of this paper is to apply the Faraday self-induction magnetic equation, recently extended to torsioned space-time, by the author to show that it lends support to physics in Riemann-Cartan space-time, in several distinct physical backgrounds. Backreaction magnetic effects are used to obtain the LV bounds. Previously Bamba et al. (JCAP 10:058, 2012) have used the torsion trace in their teleparallel investigation of the IGMF, with the argument that the torsion trace leads to less weaker effects than the other irreducible components of the torsion tensor. LV is computed in terms of a chiral-torsion-like current in the new dynamo equation analogous to the Dvornikov and Semikoz dynamo equation with chiral magnetic currents. Making use of the chiral-torsion dynamo equation we estimate the LV bounds in the early universe to be of the order of 10{sup -24} GeV, which was the order of the charged-lepton sector. Our main result is that it is possible to obtain more stringent bounds than the ones found in the fermion sector of astrophysics in the new revised 2017 data table for CPT and Lorentz violation by Kostelecky and Mewes. They found in several astrophysical backgrounds, orders of magnitude such as 10{sup -24} and 10{sup -23} Ge

  14. (. gamma. , p) reaction of /sup 51/V and /sup 54/Fe

    Energy Technology Data Exchange (ETDEWEB)

    Tsubota, H [Tohoku Univ., Sendai (Japan). Coll. of General Education; Oikawa, S; Uegaki, J; Tamae, T

    1975-06-01

    The (..gamma.., p) reaction cross sections of /sup 51/V and /sup 54/Fe were measured for studying the isospin and the nuclear deformation effects. An approximate method of the analysis of the isospin effect is presented. The form and intensity of the (..gamma.., p) and (..gamma.., n) reaction cross sections in the giant resonance region of /sup 51/V and /sup 54/Fe can be explained qualitatively with a compound nucleus model and the assumption of a quantum number of good isospin.

  15. 7 CFR 51.45 - Fees and charges at shipping point areas.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Fees and charges at shipping point areas. 51.45 Section 51.45 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE..., AND STANDARDS) Regulations 1 Schedule of Fees and Charges at Shipping Point Areas § 51.45 Fees and...

  16. Precipitate-induced R-phase in martensitic transformation of as-spun and annealed Ti51Ni49 ribbons

    International Nuclear Information System (INIS)

    Wu, Ling-Mei; Chang, Shih-Hang; Wu, Shyi-Kaan

    2010-01-01

    Differential scanning calorimetry (DSC) results indicate that a two-step B2 → R → B19' martensitic transformation and a one-step B19' → B2 transformation exhibit in as-spun and in 200-600 o C annealed Ti 51 Ni 49 ribbons. Guinier-Preston (GP) zones and Ti 2 Ni precipitates are formed in ribbons annealed at ≤300 o C and ≥400 o C, respectively, and a conspicuous increase of DSC transformation peak temperature occurs in between 300 o C and 400 o C. The sizes of GP zones and Ti 2 Ni precipitates increase with increased annealing temperature. Transmission electron microscope (TEM) observations show that GP zones can induce the R-phase and both of them are formed along B2 directions. DSC and TEM tests show that Ti 2 Ni precipitates can induce the R-phase more than GP zones and the induced R-phase plates are also found along B2 directions. Experimental results show that the growing direction of R-phase plates is strongly confined by that of GP zones and Ti 2 Ni precipitates. The length of R-phase plates can reach about 2 μm in 300 o C annealed ribbon.

  17. Density functional calculations on the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 (M = Sc–Ni)

    International Nuclear Information System (INIS)

    Chun-Mei, Tang; Wei-Hua, Zhu; Kai-Ming, Deng

    2010-01-01

    This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C 20 F 20 (M = Sc–Ni). The geometric optimization shows that the cage centre is the most stable position for M, forming the structure named as M@C 20 F 20 -4. The inclusion energy, zero-point energy, and energy gap calculations tell us that N@C 20 F 20 -4 should be thermodynamically and kinetically stablest. M@C 20 F 20 -4 (M = Sc–Co) possesses high magnetic moments varied from 1 to 6 μ B , while Ni@C 20 F 20 -4 is nonmagnetic. The Ni–C bond in Ni@C 20 F 20 -4 contains both the covalent and ionic characters

  18. 7 CFR 51.2078 - U.S. No. 2 Mixed.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Mixed. 51.2078 Section 51.2078 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946...

  19. 7 CFR 51.2076 - U.S. No. 1 Mixed.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Mixed. 51.2076 Section 51.2076 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946...

  20. 9 CFR 51.29 - Destruction of animals; time limit.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Destruction of animals; time limit. 51.29 Section 51.29 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES ANIMALS DESTROYED...

  1. 10 CFR 51.70 - Draft environmental impact statement-general.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Draft environmental impact statement-general. 51.70... Implementing Section 102(2) Environmental Impact Statements § 51.70 Draft environmental impact statement—general. (a) The NRC staff will prepare a draft environmental impact statement as soon as practicable...

  2. 10 CFR 51.71 - Draft environmental impact statement-contents.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Draft environmental impact statement-contents. 51.71... Implementing Section 102(2) Environmental Impact Statements § 51.71 Draft environmental impact statement—contents. (a) Scope. The draft environmental impact statement will be prepared in accordance with the scope...

  3. 7 CFR 550.51 - Purpose of reports and records.

    Science.gov (United States)

    2010-01-01

    ... forth the procedures for monitoring and reporting on the Cooperator's financial and program performance... 7 Agriculture 6 2010-01-01 2010-01-01 false Purpose of reports and records. 550.51 Section 550.51... OF AGRICULTURE GENERAL ADMINISTRATIVE POLICY FOR NON-ASSISTANCE COOPERATIVE AGREEMENTS Management of...

  4. 7 CFR 51.1177 - U.S. Grade A Juice.

    Science.gov (United States)

    2010-01-01

    ... STANDARDS) United States Standards for Grades of Florida Oranges and Tangelos Standards for Internal Quality... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Grade A Juice. 51.1177 Section 51.1177 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards...

  5. 26 CFR 1.142(a)(5)-1 - Exempt facility bonds: Sewage facilities.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Exempt facility bonds: Sewage facilities. 1.142... Bonds § 1.142(a)(5)-1 Exempt facility bonds: Sewage facilities. (a) In general. Under section 103(a), a... in section 142(a) is a sewage facility. This section defines the term sewage facility for purposes of...

  6. 7 CFR 51.346 - Tolerances.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples for Processing Tolerances § 51.346 Tolerances. When a lot of apples is...

  7. 7 CFR 51.344 - Size.

    Science.gov (United States)

    2010-01-01

    ... the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples for Processing Size § 51.344 Size. (a) The minimum and maximum sizes or range...

  8. 7 CFR 51.343 - Culls.

    Science.gov (United States)

    2010-01-01

    ... of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples for Processing Culls § 51.343 Culls. “Culls” consist of apples which fail to...

  9. 7 CFR 51.306 - Tolerances.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Tolerances § 51.306 Tolerances. In order to allow for variations incident to...

  10. 7 CFR 51.314 - Clean.

    Science.gov (United States)

    2010-01-01

    ... of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.314 Clean. “Clean” means that the apples are free from...

  11. 7 CFR 51.2556 - Grades.

    Science.gov (United States)

    2010-01-01

    ... Standards for Grades of Shelled Pistachio Nuts § 51.2556 Grades. (a) “U.S. Fancy,” “U.S. Extra No. 1,” and “U.S. No. 1” consist of pistachio kernels which meet the following requirements: (1) Well dried, or...

  12. STS-51J Mission Insignia

    Science.gov (United States)

    1985-01-01

    The 51-J mission insignia, designed by Atlantis's first crew, pays tribute to the Statue of Liberty and the ideas it symbolizes. The historical gateway figure bears additional significance for Astronauts Karol J. Bobko, mission commander; and Ronald J. Grabe, pilot, both New Your Natives.

  13. 28 CFR 51.58 - Representation.

    Science.gov (United States)

    2010-07-01

    ... THE VOTING RIGHTS ACT OF 1965, AS AMENDED Determinations by the Attorney General § 51.58... which minorities have been denied an equal opportunity to participate meaningfully in the political... voting in the jurisdiction is racially polarized and political activities are racially segregated. (4...

  14. 7 CFR 51.638 - Discoloration.

    Science.gov (United States)

    2010-01-01

    ...) Definitions § 51.638 Discoloration. Discoloration means russeting of light shade of golden brown caused by... area, provided no discoloration caused by speck type melanose or other means may detract from the... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  15. Radioisotopic 51Cr-leukocyte adherence inhibition (LAI) assay. I

    International Nuclear Information System (INIS)

    Tsang, P.H.; Tangnavarad, K.; Lesnick, G.; Holland, J.F.; Bekesi, J.G.; Perloff, M.

    1980-01-01

    A simplified radioisotopic leukocyte adherence inhibition assay ( 51 Cr-LAI assay) was used to determine tumor-directed immune responses in patients with cancer of the breast. Essential steps in development of this assay are the standardization of conditions for optimal 51 Cr uptake by peripheral blood lymphocytes (PBL) and the inclusion of autologous or normal AB serum in the incubation media. A dextrose salt mixture (GNK) was found to enhance intracellular uptake of 51 Cr significantly (8-fold) without affecting viability of the cells or without causing selective loss of lymphocyte subpopulations. The presence of 10% autologous or normal AB serum prevented non-specific LAI responses to unrelated tumor antigens. Experimental results are presented and it is seen that this short term (4 h) 51 Cr-LAI assay provides reproducible and specific results analogous to those using tube-LAI assay. The test has the advantages of being accurate, sensitive and free from technical bias. (Auth.)

  16. Molecular Basis for Enhancement of the Meiotic DMCI Recombinase by RAD51AP1

    Energy Technology Data Exchange (ETDEWEB)

    Dray, Eloise; Dunlop, Myun Hwa; Kauppi, Liisa; San Filippo, Joseph San; Wiese, Claudia; Tsai, Miaw-Sheue; Begovic, Sead; Schild, David; Jasin, Maria; Keeney, Scott; Sung, Patrick

    2010-11-05

    Homologous recombination is needed for meiotic chromosome segregation, genome maintenance, and tumor suppression. RAD51AP1 (RAD51 Associated Protein 1) has been shown to interact with and enhance the recombinase activity of RAD51. Accordingly, genetic ablation of RAD51AP1 leads to enhanced sensitivity to and also chromosome aberrations upon DNA damage, demonstrating a role for RAD51AP1 in mitotic homologous recombination. Here we show physical association of RAD51AP1 with the meiosis-specific recombinase DMC1 and a stimulatory effect of RAD51AP1 on the DMC1-mediated D-loop reaction. Mechanistic studies have revealed that RAD51AP1 enhances the ability of the DMC1 presynaptic filament to capture the duplex DNA partner and to assemble the synaptic complex, in which the recombining DNA strands are homologously aligned. We also provide evidence that functional co-operation is dependent on complex formation between DMC1 and RAD51AP1, and that distinct epitopes in RAD51AP1 mediate interactions with RAD51 and DMC1. Finally, we show that RAD51AP1 is expressed in mouse testes, and that RAD51AP1 foci co-localize with a subset of DMC1 foci in spermatocytes. These results suggest that RAD51AP1 also serves an important role in meiotic homologous recombination.

  17. Excretion of radionuclides in human breast milk following administration of 125I-fibrinogen, 99Tc/sup m/-MAA and 51Cr-EDTA

    International Nuclear Information System (INIS)

    Mattsson, S.; Johansson, L.; Nosslin, B.; Ahlgren, L.

    1981-01-01

    Very few biokinetic and dosimetric data for estimating the absorbed dose to a breast-feeding child are available in the literature. The few available are usually case reports. We have measured the activity concentration in breast milk from one patient after administration of 125 I-fibrinogen, from two patients after administration of 99 Tc/sup m/-macroaggregated albumin, and from one patient after administration of 51 Cr-EDTA. We have compared our data with earlier published results and estimated the absorbed dose to the breast-feeding child using biokinetic data presented in this work and recently published S-values for new-born children

  18. 45 CFR 1309.51 - Submission of drawings and specifications.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Submission of drawings and specifications. 1309.51... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND... and Major Renovation § 1309.51 Submission of drawings and specifications. (a) The grantee may not...

  19. 41 CFR 51-2.6 - Reconsideration of Committee decision.

    Science.gov (United States)

    2010-07-01

    ... decision as factors weighing toward a decision to delete the item, and information concerning possible harm... Committee decision. 51-2.6 Section 51-2.6 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 2-COMMITTEE...

  20. Comparison between 125IUdR and 51Cr as cell labels in investigations of tumor cell migration

    DEFF Research Database (Denmark)

    Basse, P; Hokland, P; Hokland, M

    1991-01-01

    YAC-1 tumor cells double-labeled with Na2[51Cr]O4 [51Cr] and [125I]iododeoxyuridine [125IUdR] were injected intravenously into Balb/c mice in order to investigate their migration and fate 0-4 h after the injection. Whereas the clearance of tumor cells from the lung tissue was similar as judged...

  1. 12 CFR 5.1 - Scope.

    Science.gov (United States)

    2010-01-01

    ... COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES, POLICIES, AND PROCEDURES FOR CORPORATE ACTIVITIES § 5.1 Scope. This part establishes rules, policies and procedures of the Office of the Comptroller of the Currency (OCC) for corporate activities and transactions involving national banks. It contains...

  2. 42 CFR 456.51 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... institution for mental disease, as defined in § 440.10; (2) [Reserved] (3) Services provided in specialty hospitals and (b) Exclude services provided in mental hospitals. Utilization control requirements for mental... ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Hospitals § 456.51 Definitions. As used in this...

  3. 22 CFR 51.53 - Refunds.

    Science.gov (United States)

    2010-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Fees § 51.53 Refunds. (a) The Department will refund the passport application fee and the security surcharge to any person exempt from payment of passport... expedited passport processing fee if the Department fails to provide expedited passport processing as...

  4. 7 CFR 51.700 - Discoloration.

    Science.gov (United States)

    2010-01-01

    ... § 51.700 Discoloration. Discoloration means russeting of light shade of golden brown caused by rust..., provided no discoloration caused by melanose or other means may affect the appearance of the fruit to a... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...

  5. Generation of the V4.2m5 and AMPX and MPACT 51 and 252-Group Libraries with ENDF/B-VII.0 and VII.1

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kang Seog [Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). Consortium for Advanced Simulation of LWRs (CASL)

    2016-12-12

    The evaluated nuclear data file (ENDF)/B-7.0 v4.1m3 MPACT 47-group library has been used as a main library for the Consortium for Advanced Simulation of Light Water Reactors (CASL) neutronics simulator in simulating pressurized water reactor (PWR) problems. Recent analysis for the high void boiling water reactor (BWR) fuels and burnt fuels indicates that the 47-group library introduces relatively large reactivity bias. Since the 47- group structure does not match with the SCALE 6.2 252-group boundaries, the CASL Virtual Environment for Reactor Applications Core Simulator (VERA-CS) MPACT library must be maintained independently, which causes quality assurance concerns. In order to address this issue, a new 51-group structure has been proposed based on the MPACT 47- g and SCALE 252-g structures. In addition, the new CASL library will include a 19-group structure for gamma production and interaction cross section data based on the SCALE 19- group structure. New AMPX and MPACT 51-group libraries have been developed with the ENDF/B-7.0 and 7.1 evaluated nuclear data. The 19-group gamma data also have been generated for future use, but they are only available on the AMPX 51-g library. In addition, ENDF/B-7.0 and 7.1 MPACT 252-g libraries have been generated for verification purposes. Various benchmark calculations have been performed to verify and validate the newly developed libraries.

  6. Generation of the V4.2m5 and AMPX and MPACT 51 and 252-Group Libraries with ENDF/B-VII.0 and VII.1

    International Nuclear Information System (INIS)

    Kim, Kang Seog

    2016-01-01

    The evaluated nuclear data file (ENDF)/B-7.0 v4.1m3 MPACT 47-group library has been used as a main library for the Consortium for Advanced Simulation of Light Water Reactors (CASL) neutronics simulator in simulating pressurized water reactor (PWR) problems. Recent analysis for the high void boiling water reactor (BWR) fuels and burnt fuels indicates that the 47-group library introduces relatively large reactivity bias. Since the 47- group structure does not match with the SCALE 6.2 252-group boundaries, the CASL Virtual Environment for Reactor Applications Core Simulator (VERA-CS) MPACT library must be maintained independently, which causes quality assurance concerns. In order to address this issue, a new 51-group structure has been proposed based on the MPACT 47- g and SCALE 252-g structures. In addition, the new CASL library will include a 19-group structure for gamma production and interaction cross section data based on the SCALE 19- group structure. New AMPX and MPACT 51-group libraries have been developed with the ENDF/B-7.0 and 7.1 evaluated nuclear data. The 19-group gamma data also have been generated for future use, but they are only available on the AMPX 51-g library. In addition, ENDF/B-7.0 and 7.1 MPACT 252-g libraries have been generated for verification purposes. Various benchmark calculations have been performed to verify and validate the newly developed libraries.

  7. Nonextensive Pythagoras' Theorem

    OpenAIRE

    Dukkipati, Ambedkar

    2006-01-01

    Kullback-Leibler relative-entropy, in cases involving distributions resulting from relative-entropy minimization, has a celebrated property reminiscent of squared Euclidean distance: it satisfies an analogue of the Pythagoras' theorem. And hence, this property is referred to as Pythagoras' theorem of relative-entropy minimization or triangle equality and plays a fundamental role in geometrical approaches of statistical estimation theory like information geometry. Equvalent of Pythagoras' theo...

  8. 45 CFR 81.51 - Notice of hearing or opportunity for hearing.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Notice of hearing or opportunity for hearing. 81.51 Section 81.51 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRACTICE AND PROCEDURE FOR HEARINGS UNDER PART 80 OF THIS TITLE Proceedings Prior to Hearing § 81.51 Notice of hearing or opportunity for hearing....

  9. 32 CFR 728.51 - General provisions-the “Economy Act.”

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false General provisions-the âEconomy Act.â 728.51 Section 728.51 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Beneficiaries of Other Federal Agencies § 728.51 General provisions—th...

  10. The synthesis of 5-(1- sup 11 C)ethyl barbiturates from labelled malonic esters

    Energy Technology Data Exchange (ETDEWEB)

    Gee, A.; Laangstroem, B. (Uppsala Univ. (Sweden). Dept. of Organic Chemistry)

    1991-01-01

    The synthesis of ({sup 11}C)phenobarbital, ({sup 11}C)pentobarbital and({sup 11}C)amobarbital labelled in the 5-(1-{sup 11}C)ethyl position is reported. The malonic esters R- CH(CO{sub 2}Et){sub 2} R phenyl-, 1-methylbutyl-, and 3- methylbutyl- were alkylated with (1-{sup 11}C)ethyl iodide prepared from ({sup 11}C)carbon dioxide. Ring closure of the 2-(1-{sup 11}C)ethyl-labelled malonic esters with urea afforded 5-(1-{sup 11}C)ethyl-phenobarbital,-phenobarbital, -pentobarbital and -amobarbital synthesis times of 42-47 min, counted from ({sup 11}C) carbon dioxide. In typical syntheses starting with 3 GBq pentobarbitol and (81 mCi) ({sup 11}C)carbon dioxide, 150-215 MBq (4-6 mCi) were produced in 25-30% decay corrected -amobarbital radiochemical yields with radiochemical purities greater than 98%. (author).

  11. 40 CFR 51.860 - Mitigation of air quality impacts.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Mitigation of air quality impacts. 51... Federal Actions to State or Federal Implementation Plans § 51.860 Mitigation of air quality impacts. Link... mitigate air quality impacts must be identified and the process for implementation and enforcement of such...

  12. OsRAD51C Is Essential for Double Strand Break Repair in Rice Meiosis

    Directory of Open Access Journals (Sweden)

    Ding eTang

    2014-05-01

    Full Text Available RAD51C is one of the RAD51 paralogs that plays an important role in DNA double-strand break repair by homologous recombination. Here, we identified and characterized OsRAD51C, the rice homolog of human RAD51C. The Osrad51c mutant plant is normal in vegetative growth but exhibits complete male and female sterility. Cytological investigation revealed that homologous pairing and synapsis were severely disrupted. Massive chromosome fragmentation occurred during metaphase I in Osrad51c meiocytes, and was fully suppressed by the CRC1 mutation. Immunofluorescence analysis showed that OsRAD51C localized onto the chromosomes from leptotene to early pachytene during prophase I, and that normal loading of OsRAD51C was dependent on OsREC8, PAIR2, and PAIR3. Additionally, ZEP1 did not localize properly in Osrad51c, indicating that OsRAD51C is required for synaptonemal complex assembly. Our study also provided evidence in support of a functional divergence in RAD51C among organisms.

  13. Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells.

    Science.gov (United States)

    Choi, Eui-Hwan; Yoon, Seobin; Hahn, Yoonsoo; Kim, Keun P

    2017-02-01

    Homologous recombination (HR) is necessary for maintenance of genomic integrity and prevention of various mutations in tumor suppressor genes and proto-oncogenes. Rad51 and Rad54 are key HR factors that cope with replication stress and DNA breaks in eukaryotes. Rad51 binds to single-stranded DNA (ssDNA) to form the presynaptic filament that promotes a homology search and DNA strand exchange, and Rad54 stimulates the strand-pairing function of Rad51. Here, we studied the molecular dynamics of Rad51 and Rad54 during the cell cycle of HeLa cells. These cells constitutively express Rad51 and Rad54 throughout the entire cell cycle, and the formation of foci immediately increased in response to various types of DNA damage and replication stress, except for caffeine, which suppressed the Rad51-dependent HR pathway. Depletion of Rad51 caused severe defects in response to postreplicative stress. Accordingly, HeLa cells were arrested at the G2-M transition although a small amount of Rad51 was steadily maintained in HeLa cells. Our results suggest that cell cycle progression and proliferation of HeLa cells can be tightly controlled by the abundance of HR proteins, which are essential for the rapid response to postreplicative stress and DNA damage stress.

  14. Regulation of homologous recombination repair protein Rad51 by Ku70

    International Nuclear Information System (INIS)

    Du Liqing; Liu Qiang; Wang Yan; Xu Chang; Cao Jia; Fu Yue; Chen Fenghua; Fan Feiyue

    2013-01-01

    Objective: To explore the regulative effect of non-homologous end joining (NHEJ)protein Ku70 on homologous recombination repair protein Rad51, and to investigate the synergistic mechanism of homologous recombination repair in combination with NHEJ. Methods: Observed Rad51 protein expression after transfect Ku70 small interfering RNA or Ku70 plasmid DNA into tumor cells using Western blot. Results: Expression of Rad51 was obviously reduced after pretreated with Ku70 small interfering RNA. And with the increasing expression of Ku70 protein after transfection of Ku70 plasmid DNA PGCsi3.0-hKu70 into tumor cell lines, the Rad51 protein expression was increased. Conclusion: Ku70 protein has regulating effect on gene expression of Rad51, and it might participate in the collaboration between homologous recombination repair and NHEJ. (authors)

  15. Characterisation of the novel deleterious RAD51C p.Arg312Trp variant and prioritisation criteria for functional analysis of RAD51C missense changes.

    Science.gov (United States)

    Gayarre, Javier; Martín-Gimeno, Paloma; Osorio, Ana; Paumard, Beatriz; Barroso, Alicia; Fernández, Victoria; de la Hoya, Miguel; Rojo, Alejandro; Caldés, Trinidad; Palacios, José; Urioste, Miguel; Benítez, Javier; García, María J

    2017-09-26

    Despite a high prevalence of deleterious missense variants, most studies of RAD51C ovarian cancer susceptibility gene only provide in silico pathogenicity predictions of missense changes. We identified a novel deleterious RAD51C missense variant (p.Arg312Trp) in a high-risk family, and propose a criteria to prioritise RAD51C missense changes qualifying for functional analysis. To evaluate pathogenicity of p.Arg312Trp variant we used sequence homology, loss of heterozygosity (LOH) and segregation analysis, and a comprehensive functional characterisation. To define a functional-analysis prioritisation criteria, we used outputs for the known functionally confirmed deleterious and benign RAD51C missense changes from nine pathogenicity prediction algorithms. The p.Arg312Trp variant failed to correct mitomycin and olaparib hypersensitivity and to complement abnormal RAD51C foci formation according to functional assays, which altogether with LOH and segregation data demonstrated deleteriousness. Prioritisation criteria were based on the number of predictors providing a deleterious output, with a minimum of 5 to qualify for testing and a PredictProtein score greater than 33 to assign high-priority indication. Our study points to a non-negligible number of RAD51C missense variants likely to impair protein function, provides a guideline to prioritise and encourage their selection for functional analysis and anticipates that reference laboratories should have available resources to conduct such assays.

  16. 49 CFR 1.51 - Delegations to Federal Transit Administrator.

    Science.gov (United States)

    2010-10-01

    ... Plan No. 2 of 1968 (5 U.S.C. app. 1). (c) Section 10 of the Urban Mass Transportation Assistance Act of... 49 Transportation 1 2010-10-01 2010-10-01 false Delegations to Federal Transit Administrator. 1.51 Section 1.51 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF...

  17. Study of the /sup 51/Cr release assay system in micro-method

    Energy Technology Data Exchange (ETDEWEB)

    Kiya, K.; Harada, K.; Uozumi, T. (Hiroshima Univ. (Japan). School of Medicine); Toge, T.; Hattori, T.

    1981-05-01

    Conditions of /sup 51/Cr release assay in microculture were investigated to measure the natural cytotoxic (NC) activity of mouse spleen cells. Malignant glioma (MG) cells of C57BL/6 mouse, induced by 20-methylcholanthrene, were labeled with Na/sub 2//sup 51/CrO/sub 4/. Spleen cells collected from the same mouse strain were suspended in Eagle's MEM. Labeled MG cells and spleen cells were incubated for several hours in a CO/sub 2/ incubator. Then the activity of the supernatant was measured by an automatic gamma counter. The optimum conditions of /sup 51/Cr release assay in micro-culture were, (1) number of the target cells: 5 x 10/sup 3// well (2) FCS concentration: 10% (3) E/T ratio: less than 100 : 1, 50 : 1 was possible (4) incubation time: 15 hours. The number of the target cells at labeling incubation was set to 2 x 10/sup 6//ml. Though the natural release of /sup 51/Cr was not effected by the viability of the target cells, it was suggested that the NC activity was dependent on the viability of both cells, target and effector cells.

  18. The young star cluster population of M51 with LEGUS - II. Testing environmental dependences

    Science.gov (United States)

    Messa, Matteo; Adamo, A.; Calzetti, D.; Reina-Campos, M.; Colombo, D.; Schinnerer, E.; Chandar, R.; Dale, D. A.; Gouliermis, D. A.; Grasha, K.; Grebel, E. K.; Elmegreen, B. G.; Fumagalli, M.; Johnson, K. E.; Kruijssen, J. M. D.; Östlin, G.; Shabani, F.; Smith, L. J.; Whitmore, B. C.

    2018-06-01

    It has recently been established that the properties of young star clusters (YSCs) can vary as a function of the galactic environment in which they are found. We use the cluster catalogue produced by the Legacy Extragalactic UV Survey (LEGUS) collaboration to investigate cluster properties in the spiral galaxy M51. We analyse the cluster population as a function of galactocentric distance and in arm and inter-arm regions. The cluster mass function exhibits a similar shape at all radial bins, described by a power law with a slope close to -2 and an exponential truncation around 105 M⊙. While the mass functions of the YSCs in the spiral arm and inter-arm regions have similar truncation masses, the inter-arm region mass function has a significantly steeper slope than the one in the arm region, a trend that is also observed in the giant molecular cloud mass function and predicted by simulations. The age distribution of clusters is dependent on the region considered, and is consistent with rapid disruption only in dense regions, while little disruption is observed at large galactocentric distances and in the inter-arm region. The fraction of stars forming in clusters does not show radial variations, despite the drop in the H2 surface density measured as a function of galactocentric distance. We suggest that the higher disruption rate observed in the inner part of the galaxy is likely at the origin of the observed flat cluster formation efficiency radial profile.

  19. On Newton’s shell theorem

    Science.gov (United States)

    Borghi, Riccardo

    2014-03-01

    In the present letter, Newton’s theorem for the gravitational field outside a uniform spherical shell is considered. In particular, a purely geometric proof of proposition LXXI/theorem XXXI of Newton’s Principia, which is suitable for undergraduates and even skilled high-school students, is proposed. Minimal knowledge of elementary calculus and three-dimensional Euclidean geometry are required.

  20. Abundâncias químicas de uma amostra de nebulosas planetárias em M51

    Science.gov (United States)

    Uchida, M. M. M.; Costa, R. D. D.; Maciel, W. J.

    2003-08-01

    A derivação de abundâncias químicas de nebulosas planetárias permite a investigação dos processos de enriquecimento químico ocorridos durante a evolução das estrelas progenitoras, que têm massas entre 0.8 e 8 massas solares. Adicionalmente as abundâncias de elementos como oxigênio, argônio ou neônio, que não são produzidos por nucleossíntese na progenitora, refletem a evolução do meio interestelar: estrelas menos massivas, de evolução mais lenta, tipicamente originam-se de um meio interestelar mais pobre. Reportamos aqui a derivação de parâmetros físicos e abundâncias químicas de uma amostra de nebulosas planetárias da galáxia M51, uma galáxia de tipo Seyfert 2 pertencente ao Grupo de Sculptor. As observações foram feitas com o telescópio Gemini Norte, usando o espectrógrafo GMOS no modo multi-objeto. Os resultados indicam uma distribuição de abundâncias análoga àquela das planetárias da Galáxia. A amostra observada não permite estabelecer-se com clareza a existência de um gradiente radial como é esperado pelos modelos evolutivos de galáxias expirais; espera-se que uma extensão desta amostra deva indicá-lo posteriormente. (FAPESP/CNPq)