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Sample records for byssinosis

  1. First report of byssinosis in Hong Kong.

    OpenAIRE

    Morgan, P G; Ong, S. G.

    1981-01-01

    There has been no report of byssinosis in Hong Kong although the textile industry has been one of the leading industries for many years. Three workers with a long history of exposure to cotton dust had chronic obstructive airways disease precipitated by their work environment. One had irreversible airways obstruction but none had chronic bronchitis, emphysema, or asthma. Only one gave a history of "Monday morning tightness," and this was attributed to the fact that most of the textile workers...

  2. Mondays without dread: the Trade Union response to byssinosis in the Lancashire cotton industry in the twentieth century.

    Science.gov (United States)

    Bowden, Sue; Tweedale, Geoffrey

    2003-04-01

    Trade unions have often been criticized for their failure to address occupational health issues. This article explores their response to byssinosis-a chronic respiratory disease caused by exposure to cotton dust that was rife in the Lancashire cotton industry in the early nineteenth and twentieth centuries. Using the archives of the cardroom and spinning unions, it is demonstrated that trade union efforts to combat byssinosis began before the First World War and were sustained for over 70 years. During that period, byssinosis became a recognized medical condition and a compensatable disease, due in no small measure to the trade unions campaigning tirelessly for better dust control, compensation for all affected workers, and more medical research. PMID:14598818

  3. Bissinose no município da capital do Estado de S. Paulo, Brasil Byssinosis in the county of S. Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Diogo Pupo Nogueira

    1973-09-01

    Full Text Available Seguindo-se uma sistemática epidemiológica, foram estudados os trabalhadores de 3 fiações de algodão, com diferentes quantidades de poeira de algodão em suspensão na atmosfera dos locais de trabalho, comparando-se com 135 pessoas do grupo controle não exposto a essas poeiras. Pelas respostas ao questionário padrão internacional sobre doenças respiratórias, verificou-se que os trabalhadores das fábricas, onde era mais elevada a concentração de poeira de algodão, apresentavam um ou mais sintomas característicos da bissinose; por outro lado, as provas de função pulmonar, realizadas imediatamente antes e após o início do trabalho às segundas-feiras, mostravam-se alteradas. Como no grupo controle, verificou-se melhoria significativa da função pulmonar no término do dia de trabalho. E como tal fato não foi observado mesmo na fábrica onde a concentração de poeira no ar era muito baixa e onde não se notou piora das provas de função pulmonar entre seus trabalhadores, levantou-se a hipótose de que essa ausência de melhoria possa constituir um sintoma precoce da bissinose.Workers of three cotton spinneries, with different amounts of cotton dust in the athmosphere of work places, were studied according to the epidemiological method of study proposed by Schilling, as compared with 135 workers not exposed to cotton dust. Through the answers to the international questionnaire on lung diseases, it was disclosed that workers from mills with highest concentration of cotton dust in the air presented symptoms characteristic of byssinosis; on the other hand, lung function tests performed on mondays immediately after the period of work showed impairment of lung function when compared with tests performed immediately before starting work. As in the control group lung function tests actually became better after the period of work, it is supposed that the non-existence of changes in lung function after work in mills the amount of cotton

  4. Otras enfermedades obstructivas: bisinosis, bronquitis crónica y EPOC de origen laboral y bronquitis eosinofílica Other obstructive diseases: byssinosis, chronic bronchitis and occupational COPD and eosinophilic bronchitis

    Directory of Open Access Journals (Sweden)

    F. J. Michel De la Rosa

    2005-01-01

    Full Text Available Además del asma ocupacional y las enfermedades derivadas de la inhalación aguda, otras enfermedades obstructivas también reconocen un origen laboral. Aunque en la actualidad la bisinosis es una enfermedad rara en España, describimos las características de la misma por su interés histórico dentro de las enfermedades respiratorias de origen laboral y porque todavía sigue vigente en los países en vías de desarrollo. La bronquitis crónica también puede estar relacionada con la exposición laboral a polvos y humos, con frecuencia denominada "bronquitis industrial". La relación ocupacional de la EPOC ha sido más controvertida a lo largo de la historia, pero en la actualidad esta relación está aceptada; describimos la evidencia actual que sustenta esta relación. En último lugar, describimos la bronquitis eosinofílica sin asma, entidad descrita por primera vez en 1989 y que en ocasiones también puede tener un origen laboral, compartiendo agentes etiológicos con el asma ocupacional.Besides occupational asthma and diseases derived from acute inhalation, other obstructive diseases also have an occupational origin. Although at present byssinosis is a rare disease in Spain, we describe its characteristics because of its historical interest amongst occupational respiratory diseases and because it is still relevant in developing countries. Chronic bronchitis can also be related to exposure at work to dust and smoke, and is often referred to as "industrial bronchitis". Historically, the relation of CPOD to occupation has been subject to controversy, but nowadays this relationship is accepted; we describe the present evidence supporting this relationship. Finally, we describe eosinophilic bronchitis without asthma, an entity that was described for the first time in 1989 and that can sometimes have an occupational origin, sharing aetiological agents with occupational asthma.

  5. Enterobacter agglomerans lipopolysaccharide-induced changes in pulmonary surfactant as a factor in the pathogenesis of byssinosis.

    OpenAIRE

    DeLucca, A J; Brogden, K.A.; Engen, R

    1988-01-01

    Lipopolysaccharide (LPS) from Enterobacter agglomerans and pulmonary surfactant mixtures were centrifuged in discontinuous sucrose gradients to determine whether LPS bound to surfactant and examined in a Langmuir trough with a Wilhelmy balance to determine whether LPS altered the surface activity of surfactant. The LPS was found to bind to the surfactant and altered its surface tension properties. The binding of LPS to surfactant in the lung may change the physiological properties of surfacta...

  6. Work-Related Respiratory Disorders in Persons Employed in Quebec Cotton Textile Mills – 1980 to 1995

    Directory of Open Access Journals (Sweden)

    Raymond Bégin

    1997-01-01

    Full Text Available Byssinosis, a chronic lung disease of cotton mill workers, is characterized by repeated episodes of reversible airway obstruction, which can lead to permanent alterations of lung function. When this occurs in Quebec the worker must be removed from further exposure in accordance with the provincial compensation rules. The current Quebec Occupational Safety and Health Regulation has a permissible exposure limit of 500 μg/m3, resulting in a prevalence rate of byssinosis of 2% to 5% in cotton workers. In this study the incidence of new respiratory disorders in persons employed in Quebec cotton mills from 1980 to 1995 was assessed and factors that identified byssinosis cases were analyzed. Incidence of the disease was assessed on the basis of cases referred to the Commission de Santé & Sécurité au travail du Québec (Quebec Workers’ Compensation Board from all Quebec textile plants. Analyses of age, years of employment, job description, smoking history, bronchial reactivity and lung function before and at work were used for diagnostic purposes. Incidence of new byssinosis cases from 1990 to 1995 was 2.8 cases per year per 5000 workers, slightly above the incidence from 1980 to 1989, at 1.7 cases per year. The incidence of chronic cases was stable at 1.5 cases per year, whereas that of early cases increased from 0.3 cases per year (1980 to 1989 to 1.25 cases per year (1990 to 1995. In comparison with chronic byssinosis cases, the average time of work before symptom appearance was 17±4 versus 32±1 years, P<0.001. Bronchial reactivity to methacholine (PC20 at work was below 2 mg/mL in 100% of byssinosis cases versus 14% in subjects not diagnosed with byssinosis. Decreases in forced expiratory volume in 1 s (FEV1 at work averaged 30% in the byssinosis and 6% in the nonbyssinosis subjects; peak flow rates were not different between those with and those without byssinosis. Early byssinosis cases were from three distinct plants in different

  7. Pneumoconiosis. May 1978-March 1990 (A Bibliography from the Life Sciences Collection data base). Report for May 1978-March 1990

    International Nuclear Information System (INIS)

    This bibliography contains citations concerning the lung diseases generally termed pneumoconiosis. Anthracosilicosis, asbestosis, silicosis, and byssinosis are most prominently mentioned. Chest radiography studies and pulmonary function studies are considered. Studies on human leukocyte antigen (HLA) phenotypes and their relation to the disease are also discussed. (This updated bibliography contains 180 citations, 92 of which are new entries to the previous edition.)

  8. Study of respiratory effect of short- and long-term cotton gin exposure.

    Science.gov (United States)

    Larson, R K; Barman, M L; Smith, D W; Nicol, L

    1981-04-01

    No excess of obstructive airway disease was found in a group of 265 cotton gin workers when compared with other San Joaquin Valley agricultural workers. After an average of eight weeks' employment in San Joaquin Valley cotton gins, 125 workers showed no appreciable deterioration of pulmonary function compared with pre-employment measurements. In studies of pulmonary function during a workshift, cotton gin workers showed slightly greater mean decrements than control agricultural workers. These differences did not reach a level of statistical significance and were lower than those usually found in byssinosis. The unusual temporal pattern of employment in cotton gins in California precludes a simple approach to diagnosis by symptoms. No correlation was found in this study between symptoms of byssinosis and objective decrements in FEV1. The questionnaire as proposed by the Cotton Dust Standard was found to be of no value in detecting reactors in this study of gin workers. PMID:7471886

  9. Immunologic responses to inhaled cotton dust.

    OpenAIRE

    Salvaggio, J E; O'Neil, C E; Butcher, B T

    1986-01-01

    Byssinosis, a respiratory disease of workers on cotton, flax, and soft hemp, is classically characterized as shortness of breath, cough, and chest tightness on Mondays or the first day of return to work after a time off. Exposure to these vegetable dusts can also result in other respiratory diseases, and the term cotton dust-induced respiratory disease (CDIRD) is introduced. Although clinically characterized for more than a century, the underlying pathogenesis of CDIRD remains obscure. An all...

  10. Proposed national strategies for the prevention of leading work-related diseases and injuries. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Preliminary strategies developed at the National Symposium on the Prevention of Leading Work Related Diseases and Injuries, held in Atlanta, Georgia on May 1 to 3, 1985 were revised, elaborated, and further developed. Strategies were developed for the prevention of occupational lung diseases, musculoskeletal injuries, occupational cancers, severe occupational traumatic injuries, and occupational cardiovascular diseases. Lung diseases considered included silicosis, asbestosis, lung cancer mesothelioma, coal workers' pneumoconiosis, byssinosis, occupational asthma, hypersensitivity pneumonitis, asphyxiation, irritation, pulmonary edema, brucellosis, psitticosis, anthrax, mycobacterioses, histoplasmosis, aspergillosis, and coccidioidomycosis. Occupational cancers were discussed as they occur in the lung, pleura, peritoneum, bladder, kidneys, blood, nasal cavity, skin, nasal sinuses, and liver.

  11. A longitudinal study of pulmonary function in cotton gin workers in the San Joaquin Valley.

    Science.gov (United States)

    Larson, R K; Barman, M L

    1989-10-01

    In a previous study we found no significant effects of acute exposure to the cotton gin environment on FEV1 in San Joaquin Valley gin workers compared with concurrent control subjects, nor was there an excess of obstructive lung disease among the same gin workers. The present study looked at the mean annual decline in FEV1, FEV1/FVC, and FEF25-75% in San Joaquin Valley cotton gin workers vs concurrent control subjects over four years. The FEV1 of gin workers completing all four years of the study declined 27.3 ml vs 35.5 ml in control subjects (p = 0.37); FEV1/FVC declined 0.21 percent in gin workers and 0.23 percent in control subjects (p = 0.86); FEF25-75% declined 0.058 L/s in gin workers and 0.066 L/s in control subjects (p = 0.68). Also, the mean annual rate of change of FEV1 was less among the gin workers who did not complete all four years than the gin workers completing all four years. The presence of "byssinosis" symptoms did not significantly influence the results. This prospective, longitudinal study failed to find any detrimental effect of the cotton gin environment on the rate of decline of FEV1, FEV1/FVC, and FEF25-75%. This result was independent of "byssinosis" symptoms and the effect of "dropouts." PMID:2791678

  12. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) (Northern Ireland) Regulations 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-04-04

    Under the Pneumoconiosis etc. (Workers' Compensation) Act (Northern Ireland) 1979 ('the Order') lump sum payments may be made to certain persons disabled by a disease to which the Order applies, or to dependants of persons who were so disabled immediately before they died. These Regulations further amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations (Northern Ireland) 1988 so as to increase the amounts payable under the Order. The increase in each case is 3.9 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Order applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening.

  13. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) (Northern Ireland) Regulations 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-21

    Under the Pneumoconiosis etc. (Workers' Compensation) Act (Northern Ireland) 1979 ('the Order') lump sum payments may be made to certain persons disabled by a disease to which the Order applies, or to dependants of persons who were so disabled immediately before they died. These Regulations further amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations (Northern Ireland) 1988 so as to increase the amounts payable under the Order. The increase in each case is 2.7 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Order applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening. A full regulatory impact assessment has not been produced for this instrument as it has no impact on the costs of business.

  14. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) (Northern Ireland) Regulations 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-03-29

    Under the Pneumoconiosis etc. (Workers' Compensation) Act (Northern Ireland) 1979 ('the Order') lump sum payments may be made to certain persons disabled by a disease to which the Order applies, or to dependants of persons who were so disabled immediately before they died. These Regulations further amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations (Northern Ireland) 1988 so as to increase the amounts payable under the Order. The increase in each case is 3.6 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Order applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening. A full regulatory impact assessment has not been produced for this instrument as it has no impact on the costs of business, charities or voluntary bodies.

  15. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) Regulations 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-23

    Under the Pneumoconiosis etc. (Workers' Compensation) Act 1979 'the Act' lump sum payments may be made to certain persons disabled by a disease to which the Act applies, or to dependants of persons who were so disabled immediately before they died. These Regulations amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations 1988, so as to increase the amount payable under the Act. The increase in each case is 2.7 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Act applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening. A full regulatory impact assessment has not been produced for this instrument as it has no impact on the cost of business.

  16. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) Regulations 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-03-13

    Under the Pneumoconiosis etc. (Workers' Compensation) Act 1979 'the Act' lump sum payments may be made to certain persons disabled by a disease to which the Act applies, or to dependants of persons who were so disabled immediately before they died. These Regulations amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations 1988 (SI 1988/668), so as to increase the amount payable under the Act. The increase in each case is 3.6 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Act applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening. A full regulatory impact assessment has not been produced for this instrument as it has no impact on the cost of business, charities and voluntary bodies.

  17. The Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) (Amendment) Regulations 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-03-14

    Under the Pneumoconiosis etc. (Workers' Compensation) Act 1979 'the Act' lump sum payments may be made to certain persons disabled by a disease to which the Act applies, or to dependants of persons who were so disabled immediately before they died. These Regulations amend the Pneumoconiosis etc. (Workers' Compensation) (Payment of Claims) Regulations 1988 (SI 1988/668), so as to increase the amount payable under the Act. The increase in each case is 3.9 per cent, rounded up or down to the nearest one pound as appropriate. The diseases to which the Act applies are pneumoconiosis, byssinosis, diffuse mesothelioma, primary carcinoma of the lung (where accompanied by asbestosis or diffuse pleural thickening) and diffuse pleural thickening. A full regulatory impact assessment has not been produced for this instrument as it has no impact on the cost of business, charities and voluntary bodies.

  18. Pantoea agglomerans: a marvelous bacterium of evil and good.Part I. Deleterious effects: Dust-borne endotoxins and allergens - focus on cotton dust.

    Science.gov (United States)

    Dutkiewicz, Jacek; Mackiewicz, Barbara; Lemieszek, Marta Kinga; Golec, Marcin; Milanowski, Janusz

    2015-01-01

    The ubiquitous Gram-negative bacterium Pantoea agglomerans (synonyms: Enterobacter agglomerans, Erwinia herbicola) is known both as an epiphytic microbe developing on the surface of plants and as an endophytic organism living inside the plants. The bacterium occurs also abundantly in plant and animal products, in the body of arthropods and other animals, in water, soil, dust and air, and occasionally in humans. From the human viewpoint, the role of this organism is ambiguous, both deleterious and beneficial: on one side it causes disorders in people exposed to inhalation of organic dusts and diseases of crops, and on the other side it produces substances effective in the treatment of cancer and other diseases of humans and animals, suppresses the development of various plant pathogens, promotes plant growth, and appears as a potentially efficient biofertilizer and bioremediator. P. agglomerans was identified as a predominant bacterium on cotton plant grown all over the world, usually as an epiphyte, rarely as pathogen. It is particularly numerous on cotton bract after senescence. During processing of cotton in mills, bacteria and their products are released with cotton dust into air and are inhaled by workers, causing respiratory and general disorders, usually defined as byssinosis. The most adverse substance is endotoxin, a heteropolymer macromolecule present in the outermost part of the cell wall, consisting of lipopolysaccharide (LPS) as a major constituent, phospholipids and protein. The numerous experiments carried out in last quarter of XXth century on laboratory animals and human volunteers supported a convincing evidence that the inhaled endotoxin produced by P. agglomerans causes numerous pathologic effects similar to those elicited by cotton dust, such as influx of free lung cells into airways and activation of alveolar macrophages which secrete mediators (prostaglandins, platelet-activating factor, interleukin-1, tumor necrosis factor) that cause

  19. Pantoea agglomerans: a marvelous bacterium of evil and good.Part I. Deleterious effects: Dust-borne endotoxins and allergens – focus on cotton dust

    Directory of Open Access Journals (Sweden)

    Jacek Dutkiewicz

    2015-12-01

    Full Text Available The ubiquitous Gram-negative bacterium Pantoea agglomerans (synonyms: Enterobacter agglomerans, Erwinia herbicola is known both as an epiphytic microbe developing on the surface of plants and as an endophytic organism living inside the plants. The bacterium occurs also abundantly in plant and animal products, in the body of arthropods and other animals, in water, soil, dust and air, and occasionally in humans. From the human viewpoint, the role of this organism is ambiguous, both deleterious and beneficial: on one side it causes disorders in people exposed to inhalation of organic dusts and diseases of crops, and on the other side it produces substances effective in the treatment of cancer and other diseases of humans and animals, suppresses the development of various plant pathogens, promotes plant growth, and appears as a potentially efficient biofertilizer and bioremediator. P. agglomerans was identified as a predominant bacterium on cotton plant grown all over the world, usually as an epiphyte, rarely as pathogen. It is particularly numerous on cotton bract after senescence. During processing of cotton in mills, bacteria and their products are released with cotton dust into air and are inhaled by workers, causing respiratory and general disorders, usually defined as byssinosis. The most adverse substance is endotoxin, a heteropolymer macromolecule present in the outermost part of the cell wall, consisting of lipopolysaccharide (LPS as a major constituent, phospholipids and protein. The numerous experiments carried out in last quarter of XXth century on laboratory animals and human volunteers supported a convincing evidence that the inhaled endotoxin produced by P. agglomerans causes numerous pathologic effects similar to those elicited by cotton dust, such as influx of free lung cells into airways and activation of alveolar macrophages which secrete mediators (prostaglandins, platelet-activating factor, interleukin-1, tumor necrosis factor

  20. Ventilatory impairment from pre-harvest retted flax.

    Science.gov (United States)

    Jamison, J P; Langlands, J H; Lowry, R C

    1986-12-01

    A new method of retting flax recently developed to suit the United Kingdom climate has allowed the reintroduction of flax growing to this country. The weed killer glyphosate is sprayed on the crop which then rets before harvesting six weeks later. The acute bronchoconstrictor responses of 11 normal subjects to dust from dew retted and from pre-harvest retted flaxes were compared in a double blind crossover fashion. There were no significant differences in the dust levels nor in the size of the dust particles in the experimental dust room. The decreases in pulmonary function after six hours of dust inhalation were significantly larger after pre-harvest retted flax dust than after dew retted flax dust (delta FEV1, -0.21 and -0.40 1; delta MEF50, -0.72 and -1.211/s; delta sGaw (specific airway conductance), -0.17 and -0.65 kPa/s for dew retted and pre-harvest retted respectively). The subjects also reported more symptoms after inhaling pre-harvest retted flax dust. It is concluded that the acute bronchoconstrictor response to flax dust is increased by pre-harvest retting, suggesting an increased risk of byssinosis. PMID:3801332

  1. Cotton Dust Exposure and Respiratory Disorders among Textile Workers at a Textile Company in the Southern Part of Benin.

    Science.gov (United States)

    Hinson, Antoine Vikkey; Lokossou, Virgil K; Schlünssen, Vivi; Agodokpessi, Gildas; Sigsgaard, Torben; Fayomi, Benjamin

    2016-01-01

    The textile industry sector occupies a prominent place in the economy of Benin. It exposes workers to several occupational risks, including exposure to cotton dust. To assess the effect of exposure to cotton dust on the health of workers, this study was initiated and conducted in a Beninese cotton industry company. The objective of the study was to evaluate the respiratory disorders among the textile workers exposed to cotton dust and the cross-sectional study involved 656 subjects exposed to cotton dust and 113 non-exposed subjects. The methods used are mainly based on a survey using a questionnaire of organic dust designed by the International Commission of Occupational Health (ICOH); and on the measures of lung function parameters (FEV₁ and FVC). The main results of the different analyzes revealed that subjects exposed to cotton dust have more respiratory symptoms than unexposed subjects (36.9% vs. 21.2%). The prevalence of chronic cough, expectorations, dyspnoea, asthma and chronic bronchitis are 16.8%, 9.8%, 17.3%, 2.6%, and 5.9% respectively among the exposed versus 2.6%, 0.8%, 16.8%, 0% and 0.8% among the unexposed subjects. The prevalence of byssinosis is 44.01%.The prevalence of symptoms is dependent on the sector of activity and the age of the subject. These results should encourage medical interventions and technical prevention especially since the textile industry occupies an important place in the Benin's economy.

  2. A CROSS SECTIONAL STUDY OF RESP I RATORY CONDITION IN NON TEXTILE AND TEXTILE WORKERS

    Directory of Open Access Journals (Sweden)

    Avinash P.

    2015-02-01

    Full Text Available The purpose of this study was to determine the prevalence of respiratory symptoms among cotton - ginning workers. Byssinosis is a respiratory disease caused by inhalation of cotton dust for prolonged period of time. This is most frequently occurs in the cotton mill workers. The Aim of the study is 1. Determining the proportion of workers experiencing difficulty in breathing, chest tightness, chest pain, coughing, wheezing and phlegm. 2. To evaluate the pulmonary function test variation in textile workers with non - textile workers. The present study was conducted on three groups (I, II, III of male subjects of age ranging 30 to 40 yrs, 41 to 50 yrs & 51 to 60 yrs. And each of the group is divided again into textile workers & non - textile workers. A structured questionnaire enquiring about the respiratory health was administered to the employees. And our result shows the Byssinotic symptoms were too high in cotton mill workers than control group. The pulmonary function test shows a significant reduction in lung capacity, and the mean values of FVC, FEV1, FEV1%, FEF 50%, were on negative side among cotton mill workers compared to control group and which is statistically significant.

  3. Cotton Dust Exposure and Respiratory Disorders among Textile Workers at a Textile Company in the Southern Part of Benin.

    Science.gov (United States)

    Hinson, Antoine Vikkey; Lokossou, Virgil K; Schlünssen, Vivi; Agodokpessi, Gildas; Sigsgaard, Torben; Fayomi, Benjamin

    2016-01-01

    The textile industry sector occupies a prominent place in the economy of Benin. It exposes workers to several occupational risks, including exposure to cotton dust. To assess the effect of exposure to cotton dust on the health of workers, this study was initiated and conducted in a Beninese cotton industry company. The objective of the study was to evaluate the respiratory disorders among the textile workers exposed to cotton dust and the cross-sectional study involved 656 subjects exposed to cotton dust and 113 non-exposed subjects. The methods used are mainly based on a survey using a questionnaire of organic dust designed by the International Commission of Occupational Health (ICOH); and on the measures of lung function parameters (FEV₁ and FVC). The main results of the different analyzes revealed that subjects exposed to cotton dust have more respiratory symptoms than unexposed subjects (36.9% vs. 21.2%). The prevalence of chronic cough, expectorations, dyspnoea, asthma and chronic bronchitis are 16.8%, 9.8%, 17.3%, 2.6%, and 5.9% respectively among the exposed versus 2.6%, 0.8%, 16.8%, 0% and 0.8% among the unexposed subjects. The prevalence of byssinosis is 44.01%.The prevalence of symptoms is dependent on the sector of activity and the age of the subject. These results should encourage medical interventions and technical prevention especially since the textile industry occupies an important place in the Benin's economy. PMID:27618081

  4. Cotton Dust Exposure and Respiratory Disorders among Textile Workers at a Textile Company in the Southern Part of Benin

    Science.gov (United States)

    Hinson, Antoine Vikkey; Lokossou, Virgil K.; Schlünssen, Vivi; Agodokpessi, Gildas; Sigsgaard, Torben; Fayomi, Benjamin

    2016-01-01

    The textile industry sector occupies a prominent place in the economy of Benin. It exposes workers to several occupational risks, including exposure to cotton dust. To assess the effect of exposure to cotton dust on the health of workers, this study was initiated and conducted in a Beninese cotton industry company. The objective of the study was to evaluate the respiratory disorders among the textile workers exposed to cotton dust and the cross-sectional study involved 656 subjects exposed to cotton dust and 113 non-exposed subjects. The methods used are mainly based on a survey using a questionnaire of organic dust designed by the International Commission of Occupational Health (ICOH); and on the measures of lung function parameters (FEV1 and FVC). The main results of the different analyzes revealed that subjects exposed to cotton dust have more respiratory symptoms than unexposed subjects (36.9% vs. 21.2%). The prevalence of chronic cough, expectorations, dyspnoea, asthma and chronic bronchitis are 16.8%, 9.8%, 17.3%, 2.6%, and 5.9% respectively among the exposed versus 2.6%, 0.8%, 16.8%, 0% and 0.8% among the unexposed subjects. The prevalence of byssinosis is 44.01%.The prevalence of symptoms is dependent on the sector of activity and the age of the subject. These results should encourage medical interventions and technical prevention especially since the textile industry occupies an important place in the Benin’s economy. PMID:27618081

  5. Pulmonary Symptoms and Functions in Cotton Factory Workers

    Directory of Open Access Journals (Sweden)

    Candan Öğüş

    2004-01-01

    Full Text Available To determine the effects of chronic cotton dust exposure on respiratorytract.We planned a cross sectional study in cotton textile workers. Meanworking period of all subjects had been calculated as 18.0 ± 3.7 years. Atotal of 250 (95.4% out of 262 were administered a respiratoryquestionnaire and all subjects were examined, and subjected to spirometricevaluation. 146 (%58.4 workers were exposed to cotton dust.Onehundredfour (41.6% subjects working in places without dust wereregarded as control group.No statistically significant difference in respiratory symptoms, signs andspirometric parameters was found between study groups. In spirometricevaluations, in those having complained of symptoms compatible withallergic rhinitis and byssinosis PEFR, in those with bronchialhyperreactivity FEV1, PEFR and MMEF and in those with physicalexamination findings FVC, FEV1, FEV1/FVC, PEFR, MMEF values weresignificantly lower.No statistically significant impairment of pulmonary system wasdetected in workers due to chronic cotton dust exposure for 18 years.

  6. Gene-environment interaction from international cohorts: impact on development and evolution of occupational and environmental lung and airway disease.

    Science.gov (United States)

    Gaffney, Adam; Christiani, David C

    2015-06-01

    Environmental and occupational pulmonary diseases impose a substantial burden of morbidity and mortality on the global population. However, it has been long observed that only some of those who are exposed to pulmonary toxicants go on to develop disease; increasingly, it is being recognized that genetic differences may underlie some of this person-to-person variability. Studies performed throughout the globe are demonstrating important gene-environment interactions for diseases as diverse as chronic beryllium disease, coal workers' pneumoconiosis, silicosis, asbestosis, byssinosis, occupational asthma, and pollution-associated asthma. These findings have, in many instances, elucidated the pathogenesis of these highly complex diseases. At the same time, however, translation of this research into clinical practice has, for good reasons, proceeded slowly. No genetic test has yet emerged with sufficiently robust operating characteristics to be clearly useful or practicable in an occupational or environmental setting. In addition, occupational genetic testing raises serious ethical and policy concerns. Therefore, the primary objective must remain ensuring that the workplace and the environment are safe for all. PMID:26024343

  7. [The role of the "Clinica del Lavoro Luigi Devoto" in international research].

    Science.gov (United States)

    Bertazzi, P A; Forni, Alessandra M

    2003-01-01

    During its long history, the Clinica del Lavoro Luigi Devoto has produced numerous internationally recognized scientific contributions in the specific field of occupational medicine and health, and in other broader areas as, for example, immunology, toxicology, cytogenetics. Pivotal in this activity was the figure of Enrico C. Vigliani, director of the Clinica for over 35 years. We mention here, in particular, the results of the study of "early" markers of lead intoxication; the research on the carcinogenicity of benzene and aromatic amines; the study of the pathogenesis of silicosis and byssinosis; the study of cytogenetic damage after exposure to industrial toxic chemicals; the technical research for dust abatement in mines. Such research also played a major role in the development of pulmonary medicine, toxicology and immunology in Italy, and conferred scientific dignity on the newborn "industrial hygiene" discipline thanks to the work of Nicola Zurlo. Today, the Clinica's research is maintained at international standards especially by the work of thematic Research Centers recently established within the Clinica, covering fields such as occupational and environmental toxicology, occupational oncology, ergonomics, respiratory disease and allergy, psycho-social risk factors. These Centers are also devoted to the development of innovative methods in epidemiology, toxicology, psychology, molecular biology, and ergonomic measurement for the identification and evaluation of health risks at work.

  8. Work-related lung diseases.

    Science.gov (United States)

    Weston, Ainsley

    2011-01-01

    Work-related respiratory diseases affect people in every industrial sector, constituting approximately 60% of all disease and injury mortality and 70% of all occupational disease mortality. There are two basic types: interstitial lung diseases, that is the pneumoconioses (asbestosis, byssinosis, chronic beryllium disease, coal workers' pneumoconiosis (CWP), silicosis, flock workers' lung, and farmers' lung disease), and airways diseases, such as work-related or exacerbated asthma, chronic obstructive pulmonary disease and bronchiolitis obliterans (a disease that was recognized in the production of certain foods only 10 years ago). Common factors in the development of these diseases are exposures to dusts, metals, allergens and other toxins, which frequently cause oxidative damage. In response, the body reacts by activating primary immune response genes (i.e. cytokines that often lead to further oxidative damage), growth factors and tissue remodelling proteins. Frequently, complex imbalances in these processes contribute to the development of disease. For example, tissue matrix metalloproteases can cause the degradation of tissue, as in the development of CWP small profusions, but usually overexpression of matrix metalloproteases is controlled by serum protein inhibitors. Thus, disruption of such a balance can lead to adverse tissue damage. Susceptibility to these types of lung disease has been investigated largely through candidate gene studies, which have been characteristically small, often providing findings that have been difficult to corroborate. An important exception to this has been the finding that the HLA-DPB11(E69) allele is closely associated with chronic beryllium disease and beryllium sensitivity. Although chronic beryllium disease is only caused by exposure to beryllium, inheritance of HLA-DPB1(E69) carries an increased risk of between two- and 30-fold in beryllium exposed workers. Most, if not all, of these occupationally related diseases are

  9. Occupational causes of chronic obstructive pulmonary disease.

    Science.gov (United States)

    Rushton, Lesley

    2007-01-01

    The relation between Chronic Obstructive Pulmonary Disease (COPD, including chronic bronchitis and emphysema (CBE), and exposure to coal dust is well established. This paper reviews the evidence relating to other occupational causes of COPD, including industries associated with exposure to fumes, chemical substances, and dusts. A review of key literature has been carried out with a focus on the magnitude of risks and levels of exposure causing disabling health effects. The literature suggests that elevated risks of developing COPD are clearly associated with several occupations, with risk estimates being high in some, even after taking into account the effect of confounders, such as smoking. Of particular concern are agricultural workers who can be exposed to a variety of gases and organic dusts, among whom CBE is clearly elevated, particularly for pig farmers and exposure to endotoxins, with an increased annual decline in lung function. Similarly, cotton textile workers are exposed to a mixture of substances affecting development of atopy, byssinosis, and CBE, and across-shift and long-term decline in lung function. Atopy also has an important role in the development of COPD in flour mill workers and bakers, with those sensitized to bakery allergens having a greater lung function decline than non-sensitized individuals. Welding processes involve a range of potential chemical, physical and radiation hazards. The average reduction in FEV1 associated with welding fumes is similar to that associated with smoking. Challenges in assessing the evidence include variation in diagnostic methods; concurrent exposure to cigarette smoke (direct or second-hand) and multiple work-place irritants; healthy worker selection/survivor effects; poor exposure definition. Raising awareness of occupational causes of COPD among employers, employees, and health service professionals is important.

  10. Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention.

    Science.gov (United States)

    Smolensky, Michael H; Hermida, Ramon C; Reinberg, Alain; Sackett-Lundeen, Linda; Portaluppi, Francesco

    2016-01-01

    pressure 24 h patterns (nocturnal hypertension); delayed sleep phase syndrome, non-24 h sleep/wake disorder; recurrent hypersomnia; SW intolerance; delirium; peptic ulcer disease; kidney failure; depression; mania; bipolar disorder; Parkinson's disease; Smith-Magenis syndrome; fatal familial insomnia syndrome; autism spectrum disorder; asthma; byssinosis; cancers; hand, foot and mouth disease; post-operative state; and ICU outcome. Poorly conceived medical interventions, for example nighttime dosing of synthetic corticosteroids and certain β-antagonists and cyclic nocturnal enteral or parenteral nutrition, plus lifestyle habits, including atypical eating times and chronic alcohol consumption, also can be causal of CD. Just as surprisingly are the many proven chronotherapeutic strategies available today to manage the CD of several of these medical conditions. In clinical medicine, CD seems to be a common, yet mostly unrecognized, pathologic mechanism of human disease as are the many effective chronotherapeutic interventions to remedy it. PMID:27308960