WorldWideScience

Sample records for burst slug monitors

  1. Detecting pipe bursts by monitoring water demand

    NARCIS (Netherlands)

    Bakker, M.; Vreeburg, J.H.G.; Van der Roer, M.; Sperber, V.

    2012-01-01

    An algorithm which compares measured and predicted water demands to detect pipe bursts was developed and tested on three data sets of water demand and reported pipe bursts of three years. The algorithm proved to be able to detect bursts where the water loss exceeds 30% of the average water demand in

  2. Long X-ray burst monitoring with INTEGRAL

    DEFF Research Database (Denmark)

    X-ray bursts are thermonuclear explosions on the surface of accreting neutron stars in low mass X-ray binary systems. In the frame of the INTEGRAL observational Key Programme over the Galactic Center a good number of the known X-ray bursters are frequently being monitored. An international....... Of special interest are low luminosity bursting sources that exhibit X-ray bursts of very different durations allowing to study the transition from a hydrogen-rich bursting regime to a pure helium regime and from helium burning to carbon burning. I will present results obtained from INTEGRAL archive data...... and from our previous proposal for the observation period 2006-2007. Comparing these observations with the current burst theories confirms the relation between bursting regimes and the accretion states of the system....

  3. Part 1: The detection of criticality accidents in the Commissariat a l'Energie Atomique. Part 2: The Burst Slug Detection

    International Nuclear Information System (INIS)

    In all installations where fissionable materials are handled in quantities virtually greater than the critical mass, there exists permanent risk of accidental nuclear excursion entailing a serious irradiation hazard to the personnel, in spite of all the precautions that might be taken. Immediate detection followed by rapid evacuation greatly limits the risks of irradiation due to the fission products or to the sustained nuclear reaction. The necessity for a suitable equipment for the detection of accidents of criticality is imposed by the fact that the physical phenomena accompanying a nuclear, excursion are insufficient to follow the alarm, and may lead to confusion. Taking into account the accidents which have occurred and the role expected from a detector, we choose a dose integration device for the detecting probe proper, and a system based on the coincidence of several information to trigger the alarm. At the demand of the Commission des Masses Critiques, the minimal physical and electronic features required to obtain a very reliable system with minimal risk of false alarm has been established. These features are described in some detail. The equipment constructed at the Commissariat a l'Energie Atomique on the basis of these recommendations has been tested systematically under actual conditions of nuclear excursions at the Health Physics Research Reactor of the National Laboratory at Oak Ridge. These tests have served to determine two types of detection probes which will be described: a photomultiplier and a semiconductor probe. Finally the authors present an example of a complete unit for the detection of criticality accidents in an installation for the processing of fissile material. B - The evolution of the installations for burst slug detection (BSD) in french reactors. The main part of the effort in the field of the Burst Slug Detection has been orientated on the large gas-cooled reactors where the problem of bursts slugs is associated with the economics

  4. INTEGRAL monitoring of unusually long X-ray bursts

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Falanga, M.; Kuulkers, E.;

    2008-01-01

    exceptional burst events lasting more than ~10 minutes. Half of the dozen so-called intermediate long bursts registered so far have been observed by INTEGRAL. The goal is to derive a comprehensive picture of the relationship between the nuclear ignition processes and the accretion states of the system leading......X-ray bursts are thermonuclear explosions on the surface of accreting neutron stars in X-ray binaries. As most of the known X-ray bursters are frequently observed by INTEGRAL, an international collaboration have been taking advantage of its instrumentation to specifically monitor the occurrence of...

  5. Fermi/GAMMA-RAY BURST MONITOR OBSERVATIONS OF SGR J0501+4516 BURSTS

    International Nuclear Information System (INIS)

    We present our temporal and spectral analyses of 29 bursts from SGR J0501+4516, detected with the gamma-ray burst monitor on board the Fermi Gamma-ray Space Telescope during 13 days of the source's activation in 2008 (August 22- September 3). We find that the T90 durations of the bursts can be fit with a log-normal distribution with a mean value of ∼123 ms. We also estimate for the first time event durations of soft gamma repeater (SGR) bursts in photon space (i.e., using their deconvolved spectra) and find that these are very similar to the T90 values estimated in count space (following a log-normal distribution with a mean value of ∼124 ms). We fit the time-integrated spectra for each burst and the time-resolved spectra of the five brightest bursts with several models. We find that a single power law with an exponential cutoff model fits all 29 bursts well, while 18 of the events can also be fit with two blackbody functions. We expand on the physical interpretation of these two models and we compare their parameters and discuss their evolution. We show that the time-integrated and time-resolved spectra reveal that Epeak decreases with energy flux (and fluence) to a minimum of ∼30 keV at F = 8.7 x 10-6 erg cm-2 s-1, increasing steadily afterward. Two more sources exhibit a similar trend: SGRs J1550-5418 and 1806-20. The isotropic luminosity, Liso, corresponding to these flux values is roughly similar for all sources (0.4-1.5 x 1040 erg s-1).

  6. INTEGRAL monitoring of unusually long X-ray bursts

    DEFF Research Database (Denmark)

    of the known X-ray bursters are frequently observed by INTEGRAL, in particular in the frame of the Key Programmes. Taking advantage of the INTEGRAL instrumentation, an international collaboration led by the JEM-X team at the Danish National Space Institute has been monitoring the occurrence of uncommon burst...

  7. THE FERMI-GBM X-RAY BURST MONITOR: THERMONUCLEAR BURSTS FROM 4U 0614+09

    Energy Technology Data Exchange (ETDEWEB)

    Linares, M.; Chakrabarty, D. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, Cambridge, MA 02139 (United States); Connaughton, V.; Bhat, P. N.; Briggs, M. S.; Preece, R. [CSPAR and Physics Department, University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Jenke, P.; Kouveliotou, C.; Wilson-Hodge, C. A. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Van der Horst, A. J. [Astronomical Institute ' Anton Pannekoek' , University of Amsterdam, NL-1090-GE Amsterdam (Netherlands); Camero-Arranz, A.; Finger, M.; Paciesas, W. S. [Universities Space Research Association, Huntsville, AL 35805 (United States); Beklen, E. [Physics Department, Suleyman Demirel University, 32260 Isparta (Turkey); Von Kienlin, A. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, D-85748 Garching (Germany)

    2012-12-01

    Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the NS interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor aboard the Fermi Gamma-ray Space Telescope we have detected 15 thermonuclear bursts from the NS low-mass X-ray binary 4U 0614+09 when it was accreting at nearly 1% of the Eddington limit. We measured an average burst recurrence time of 12 {+-} 3 days (68% confidence interval) between 2010 March and 2011 March, classified all bursts as normal duration bursts and placed a lower limit on the recurrence time of long/intermediate bursts of 62 days (95% confidence level). We discuss how observations of thermonuclear bursts in the hard X-ray band compare to pointed soft X-ray observations and quantify such bandpass effects on measurements of burst radiated energy and duration. We put our results for 4U 0614+09 in the context of other bursters and briefly discuss the constraints on ignition models. Interestingly, we find that the burst energies in 4U 0614+09 are on average between those of normal duration bursts and those measured in long/intermediate bursts. Such a continuous distribution in burst energy provides a new observational link between normal and long/intermediate bursts. We suggest that the apparent bimodal distribution that defined normal and long/intermediate duration bursts during the last decade could be due to an observational bias toward detecting only the longest and most energetic bursts from slowly accreting NSs.

  8. The Fermi-GBM X-Ray Burst Monitor: Thermonuclear Bursts from 4U 0614+09

    Science.gov (United States)

    Linares, M.; Connaughton, V.; Jenke, P.; van der Horst, A. J.; Camero-Arranz, A.; Kouveliotou, C.; Chakrabarty, D.; Beklen, E.; Bhat, P. N.; Briggs, M. S.; Finger, M.; Paciesas, W. S.; Preece, R.; von Kienlin, A.; Wilson-Hodge, C. A.

    2012-12-01

    Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the NS interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor aboard the Fermi Gamma-ray Space Telescope we have detected 15 thermonuclear bursts from the NS low-mass X-ray binary 4U 0614+09 when it was accreting at nearly 1% of the Eddington limit. We measured an average burst recurrence time of 12 ± 3 days (68% confidence interval) between 2010 March and 2011 March, classified all bursts as normal duration bursts and placed a lower limit on the recurrence time of long/intermediate bursts of 62 days (95% confidence level). We discuss how observations of thermonuclear bursts in the hard X-ray band compare to pointed soft X-ray observations and quantify such bandpass effects on measurements of burst radiated energy and duration. We put our results for 4U 0614+09 in the context of other bursters and briefly discuss the constraints on ignition models. Interestingly, we find that the burst energies in 4U 0614+09 are on average between those of normal duration bursts and those measured in long/intermediate bursts. Such a continuous distribution in burst energy provides a new observational link between normal and long/intermediate bursts. We suggest that the apparent bimodal distribution that defined normal and long/intermediate duration bursts during the last decade could be due to an observational bias toward detecting only the longest and most energetic bursts from slowly accreting NSs.

  9. Study on Monitoring Rock Burst through Drill Pipe Torque

    Directory of Open Access Journals (Sweden)

    Zhonghua Li

    2015-01-01

    Full Text Available This paper presents a new method to identify the danger of rock burst from the response of drill pipe torque during drilling process to overcome many defects of the conventional volume of drilled coal rubble method. It is based on the relationship of rock burst with coal stress and coal strength. Through theoretic analysis, the change mechanism of drill pipe torque and the relationship of drill pipe torque with coal stress, coal strength, and drilling speed are investigated. In light of the analysis, a new device for testing drill pipe torque is developed and a series of experiments is performed under different conditions; the results show that drill pipe torque linearly increases with the increase of coal stress and coal strength; the faster the drilling speed, the larger the drill pipe torque, and vice versa. When monitoring rock burst by drill pipe torque method, the index of rock burst is regarded as a function in which coal stress index and coal strength index are principal variables. The results are important for the forecast of rock burst in coal mine.

  10. Monitoring burst (M-burst) — A novel framework of failure localization in all-optical mesh networks

    KAUST Repository

    Ali, Mohammed L.

    2011-10-10

    Achieving instantaneous and precise failure localization in all-optical wavelength division multiplexing (WDM) networks has been an attractive feature of network fault management systems, and is particularly important when failure-dependent protection is employed. The paper introduces a novel framework of real-time failure localization in all-optical WDM mesh networks, called monitoring-burst (m-burst), which aims to initiate a graceful compromise between consumed monitoring resources and monitoring delay. Different from any previously reported solution, the proposed m-burst framework has a single monitoring node (MN) which launches optical bursts along a set of pre-defined close-loop routes, called monitoring cycles (m-cycles), to probe the links along the m-cycles. Bursts along different m-cycles are kept non-overlapping through any link of the network. By identifying the lost bursts due to single link failure events only, the MN can unambiguously localize the failed link in at least 3-connected networks. We will justify the feasibility and applicability of the proposed m-burst framework in the scenario of interest. To avoid possible collision among optical bursts launched by the MN, we define the problem of collision-free scheduling and formulate it into an integer linear program (ILP) in order to minimize the monitoring delay. Numerical results demonstrate the effectiveness of the proposed framework and the proposed solution.

  11. The Fermi-GBM X-ray burst monitor: thermonuclear bursts from 4U 0614+09

    CERN Document Server

    Linares, M; Jenke, P; van der Horst, A J; Camero-Arranz, A; Kouveliotou, C; Chakrabarty, D; Beklen, E; Bhat, P N; Briggs, M S; Finger, M; Paciesas, W; Preece, R; von Kienlin, A; Wilson-Hodge, C A

    2012-01-01

    Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the neutron star interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor (GBM) aboard the Fermi Gamma-ray Space Telescope we have detected 15 thermonuclear bursts from the NS low-mass X-ray binary 4U 0614+09, when it was accreting at nearly 1% of the Eddington limit. We measured an average burst recurrence time of 12+/-3 d (68% confidence interval) between March 2010 and March 2011, classified all bursts as normal duration bursts and placed a lower limit on the recurrence time of long/intermediate bursts of 62 d (95% confidence level). We discuss how observations of thermonuclear bursts in the hard X-ray band compare to pointed soft X-ray observations, and quantify such bandpass effects on measurements of burst radiated energy and duration. We put our results for 4U 0614+09 in the context of other bu...

  12. Localization of Gamma-Ray Bursts using the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Connaughton, V; Goldstein, A; Meegan, C A; Paciesas, W S; Preece, R D; Wilson-Hodge, C A; Gibby, M H; Greiner, J; Gruber, D; Jenke, P; Kippen, R M; Pelassa, V; Xiong, S; Yu, H -F; Bhat, P N; Burgess, J M; Byrne, D; Fitzpatrick, G; Foley, S; Giles, M M; Guiriec, S; van der Horst, A J; von Kienlin, A; McBreen, S; McGlynn, S; Tierney, D; Zhang, B -B

    2014-01-01

    The Fermi Gamma-ray Burst Monitor (GBM) has detected over 1400 Gamma-Ray Bursts (GRBs) since it began science operations in July, 2008. We use a subset of over 300 GRBs localized by instruments such as Swift, the Fermi Large Area Telescope, INTEGRAL, and MAXI, or through triangulations from the InterPlanetary Network (IPN), to analyze the accuracy of GBM GRB localizations. We find that the reported statistical uncertainties on GBM localizations, which can be as small as 1 degree, underestimate the distance of the GBM positions to the true GRB locations and we attribute this to systematic uncertainties. The distribution of systematic uncertainties is well represented (68% confidence level) by a 3.7 degree Gaussian with a non-Gaussian tail that contains about 10% of GBM-detected GRBs and extends to approximately 14 degrees. A more complex model suggests that there is a dependence of the systematic uncertainty on the position of the GRB in spacecraft coordinates, with GRBs in the quadrants on the Y-axis better l...

  13. LOCALIZATION OF GAMMA-RAY BURSTS USING THE FERMI GAMMA-RAY BURST MONITOR

    Energy Technology Data Exchange (ETDEWEB)

    Connaughton, V.; Briggs, M. S.; Burgess, J. M. [CSPAR and Physics Department, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Goldstein, A.; Wilson-Hodge, C. A. [Astrophysics Office, ZP12, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Meegan, C. A.; Jenke, P.; Pelassa, V.; Xiong, S.; Bhat, P. N. [CSPAR, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Paciesas, W. S. [Universities Space Research Association, Huntsville, AL (United States); Preece, R. D. [Department of Space Science, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Gibby, M. H. [Jacobs Technology, Inc., Huntsville, AL (United States); Greiner, J.; Yu, H.-F. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Gruber, D. [Planetarium Südtirol, Gummer 5, I-39053 Karneid (Italy); Kippen, R. M. [Los Alamos National Laboratory, NM 87545 (United States); Byrne, D.; Fitzpatrick, G.; Foley, S., E-mail: valerie@nasa.gov [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); and others

    2015-02-01

    The Fermi Gamma-ray Burst Monitor (GBM) has detected over 1400 gamma-ray bursts (GRBs) since it began science operations in 2008 July. We use a subset of over 300 GRBs localized by instruments such as Swift, the Fermi Large Area Telescope, INTEGRAL, and MAXI, or through triangulations from the InterPlanetary Network, to analyze the accuracy of GBM GRB localizations. We find that the reported statistical uncertainties on GBM localizations, which can be as small as 1°, underestimate the distance of the GBM positions to the true GRB locations and we attribute this to systematic uncertainties. The distribution of systematic uncertainties is well represented (68% confidence level) by a 3.°7 Gaussian with a non-Gaussian tail that contains about 10% of GBM-detected GRBs and extends to approximately 14°. A more complex model suggests that there is a dependence of the systematic uncertainty on the position of the GRB in spacecraft coordinates, with GRBs in the quadrants on the Y axis better localized than those on the X axis.

  14. Localization of Gamma-Ray Bursts Using the Fermi Gamma-Ray Burst Monitor

    Science.gov (United States)

    Connaughton, V.; Briggs, M. S.; Goldstein, A.; Meegan, C. A.; Paciesas, W. S.; Preece, R. D.; Wilson-Hodge, C. A.; Gibby, M. H.; Greiner, J.; Gruber, D.; Jenke, P.; Kippen, R. M.; Pelassa, V.; Xiong, S.; Yu, H.-F.; Bhat, P. N.; Burgess, J. M.; Byrne, D.; Fitzpatrick, G.; Foley, S.; Giles, M. M.; Guiriec, S.; van der Horst, A. J.; von Kienlin, A.; McBreen, S.; McGlynn, S.; Tierney, D.; Zhang, B.-B.

    2015-02-01

    The Fermi Gamma-ray Burst Monitor (GBM) has detected over 1400 gamma-ray bursts (GRBs) since it began science operations in 2008 July. We use a subset of over 300 GRBs localized by instruments such as Swift, the Fermi Large Area Telescope, INTEGRAL, and MAXI, or through triangulations from the InterPlanetary Network, to analyze the accuracy of GBM GRB localizations. We find that the reported statistical uncertainties on GBM localizations, which can be as small as 1°, underestimate the distance of the GBM positions to the true GRB locations and we attribute this to systematic uncertainties. The distribution of systematic uncertainties is well represented (68% confidence level) by a 3.°7 Gaussian with a non-Gaussian tail that contains about 10% of GBM-detected GRBs and extends to approximately 14°. A more complex model suggests that there is a dependence of the systematic uncertainty on the position of the GRB in spacecraft coordinates, with GRBs in the quadrants on the Y axis better localized than those on the X axis.

  15. Gas slug ascent through rheologically stratified conduits

    Science.gov (United States)

    Capponi, Antonio; James, Mike R.; Lane, Steve J.

    2016-04-01

    Textural and petrological evidence has indicated the presence of viscous, degassed magma layers at the top of the conduit at Stromboli. This layer acts as a plug through which gas slugs burst and it is thought to have a role in controlling the eruptive dynamics. Here, we present the results of laboratory experiments which detail the range of slug flow configurations that can develop in a rheologically stratified conduit. A gas slug can burst (1) after being fully accommodated within the plug volume, (2) whilst its base is still in the underlying low-viscosity liquid or (3) within a low-viscosity layer dynamically emplaced above the plug during the slug ascent. We illustrate the relevance of the same flow configurations at volcanic-scale through a new experimentally-validated 1D model and 3D computational fluid dynamic simulations. Applied to Stromboli, our results show that gas volume, plug thickness, plug viscosity and conduit radius control the transition between each configuration; in contrast, the configuration distribution seems insensitive to the viscosity of magma beneath the plug, which acts mainly to deliver the slug into the plug. Each identified flow configuration encompasses a variety of processes including dynamic narrowing and widening of the conduit, generation of instabilities along the falling liquid film, transient blockages of the slug path and slug break-up. All these complexities, in turn, lead to variations in the slug overpressure, mirrored by changes in infrasonic signatures which are also associated to different eruptive styles. Acoustic amplitudes are strongly dependent on the flow configuration in which the slugs burst, with both acoustic peak amplitudes and waveform shapes reflecting different burst dynamics. When compared to infrasonic signals from Stromboli, the similarity between real signals and laboratory waveforms suggests that the burst of a slug through a plug may represent a viable first-order mechanism for the generation of

  16. SGR J1550-5418 BURSTS DETECTED WITH THE FERMI GAMMA-RAY BURST MONITOR DURING ITS MOST PROLIFIC ACTIVITY

    Energy Technology Data Exchange (ETDEWEB)

    Van der Horst, A. J.; Finger, M. H. [Universities Space Research Association, NSSTC, Huntsville, AL 35805 (United States); Kouveliotou, C. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gorgone, N. M. [Connecticut College, New London, CT 06320 (United States); Kaneko, Y.; Goegues, E.; Lin, L. [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Guiriec, S.; Bhat, P. N.; Chaplin, V. L.; Goldstein, A. [University of Alabama, Huntsville, CSPAR, Huntsville, AL 35805 (United States); Granot, J. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Watts, A. L. [Astronomical Institute ' Anton Pannekoek' , University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Bissaldi, E.; Gruber, D. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, 85748 Garching (Germany); Gehrels, N.; Harding, A. K. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Gibby, M. H.; Giles, M. M., E-mail: A.J.VanDerHorst@uva.nl [Jacobs Technology, Inc., Huntsville, AL (United States); and others

    2012-04-20

    We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in 2009 January, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles, and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law (PL) with an exponential cutoff (Comptonized model), and two blackbody (BB) functions (BB+BB). In the spectral fits with the Comptonized model, we find a mean PL index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlation between the Comptonized E{sub peak} and the burst fluence and average flux. For the BB+BB fits, we find that the fluences and emission areas of the two BB functions are correlated. The low-temperature BB has an emission area comparable to the neutron star surface area, independent of the temperature, while the high-temperature BB has a much smaller area and shows an anti-correlation between emission area and temperature. We compare the properties of these bursts with bursts observed from other SGR sources during extreme activations, and discuss the implications of our results in the context of magnetar burst models.

  17. The CALET Gamma-ray Burst Monitor (CGBM)

    CERN Document Server

    Yamaoka, Kazutaka; Sakamoto, Takanori; Takahashi, Ichiro; Hara, Takumi; Yamamoto, Tatsuma; Kawakubo, Yuta; Inoue, Ry ota; Terazawa, Shunsuke; Fujioka, Rie; Senuma, Kazumasa; Nakahira, Satoshi; Tomida, Hiroshi; Ueno, Shiro; Torii, Shoji; Cherry, Michael L; Ricciarini, Sergio

    2013-01-01

    The CALET Gamma-ray Burst Monitor (CGBM) is the secondary scientific instrument of the CALET mission on the International Space Station (ISS), which is scheduled for launch by H-IIB/HTV in 2014. The CGBM provides a broadband energy coverage from 7 keV to 20 MeV, and simultaneous observations with the primary instrument Calorimeter (CAL) in the GeV - TeV gamma-ray range and Advanced Star Camera (ASC) in the optical for gamma-ray bursts (GRBs) and other X-gamma-ray transients. The CGBM consists of two kinds of scintillators: two LaBr$_3$(Ce) (7 keV - 1 MeV) and one BGO (100 keV - 20 MeV) each read by a single photomultiplier. The LaBr$_3$(Ce) crystal, used in space for the first time here for celestial gamma-ray observations, enables GRB observations over a broad energy range from low energy X-ray emissions to gamma rays. The detector performance and structures have been verified using the bread-board model (BBM) via vibration and thermal vacuum tests. The CALET is currently in the development phase of the prot...

  18. FERMI/Gamma-ray Burst Monitor upper limits assuming a magnetar origin for the repeating Fast Radio Burst source, FRB 121102

    Science.gov (United States)

    Younes, George; Kouveliotou, Chryssa; Huppenkothen, Daniela; Gogus, Ersin; Kaneko, Yuki; van der Horst, Alexander

    2016-03-01

    Spitler et al. (2016, 10.1038/nature17168) reported a repeating Fast Radio Burst source, FRB 121102, with a rate of about 3 bursts/hr. We searched the FERMI/Gamma-ray Burst Monitor (GBM) for possible gamma-ray counterparts for these events.

  19. SGR J1550-5418 bursts detected with the Fermi Gamma-ray Burst Monitor during its most prolific activity

    CERN Document Server

    van der Horst, A J; Gorgone, N M; Kaneko, Y; Baring, M G; Guiriec, S; Gogus, E; Granot, J; Watts, A L; Lin, L; Bhat, P N; Bissaldi, E; Chaplin, V L; Connaughton, V; Finger, M H; Gehrels, N; Gibby, M H; Giles, M M; Goldstein, A; Gruber, D; Harding, A K; Kaper, L; von Kienlin, A; van der Klis, M; McBreen, S; Mcenery, J; Meegan, C A; Paciesas, W S; Pe'er, A; Preece, R D; Ramirez-Ruiz, E; Rau, A; Wachter, S; Wilson-Hodge, C; Woods, P M; Wijers, R A M J

    2012-01-01

    We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in January 2009, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law with an exponential cutoff (Comptonized model), and two black-body functions (BB+BB). In the spectral fits with the Comptonized model we find a mean power-law index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlati...

  20. Initiation of slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Hanratty, T.J.; Woods, B.D. [Univ. of Illinois, Urbana, IL (United States)

    1995-12-31

    The initiation of slug flow in a horizontal pipe can be predicted either by considering the stability of a slug or by considering the stability of a stratified flow. Measurements of the shedding rate of slugs are used to define necessary conditions for the existence of a slug. Recent results show that slugs develop from an unstable stratified flow through the evolution of small wavelength waves into large wavelength waves that have the possibility of growing to form a slug. The mechanism appears to be quite different for fluids with viscosities close to water than for fluids with large viscosities (20 centipoise).

  1. The Fermi-GBM X-ray burst monitor

    Science.gov (United States)

    Linares, M.; Fermi GBM X-ray Burst Collaboration

    2010-12-01

    We discuss the first results of the Fermi-GBM all-sky search for X-ray bursts. The very large field of view and X-ray response of the Fermi-GBM make it a unique instrument to study rare, bright and short-lived X-ray bursts. We are performing a systematic search that exploits such capabilities. We present results on long/intermediate type I X-ray bursts, an unusual kind of thermonuclear bursts from accreting neutron stars, and show how Fermi-GBM is giving for the first time robust measurements of their recurrence time.

  2. Real-Time Supernova Neutrino Burst Monitor at Super-Kamiokande

    OpenAIRE

    Abe, K.; Haga, Y.; Hayato, Y.; Ikeda, M; Iyogi, K.; Kameda, J.; Kishimoto, Y.; Miura, M.; Moriyama, S.; Nakahata, M.(University of Tokyo, Institute for Cosmic Ray Research, Kamioka Observatory, Kamioka, Japan); Nakano, Y.; Nakayama, S.; Sekiya, H.; Shiozawa, M; Suzuki, Y

    2016-01-01

    We present a real-time supernova neutrino burst monitor at Super-Kamiokande (SK). Detecting supernova explosions by neutrinos in real time is crucial for giving a clear picture of the explosion mechanism. Since the neutrinos are expected to come earlier than light, a fast broadcasting of the detection may give astronomers a chance to make electromagnetic radiation observations of the explosions right at the onset. The role of the monitor includes a fast announcement of the neutrino burst dete...

  3. Real-time supernova neutrino burst monitor at Super-Kamiokande

    Science.gov (United States)

    Abe, K.; Haga, Y.; Hayato, Y.; Ikeda, M.; Iyogi, K.; Kameda, J.; Kishimoto, Y.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakano, Y.; Nakayama, S.; Sekiya, H.; Shiozawa, M.; Suzuki, Y.; Takeda, A.; Tanaka, H.; Tomura, T.; Ueno, K.; Wendell, R. A.; Yokozawa, T.; Irvine, T.; Kajita, T.; Kametani, I.; Kaneyuki, K.; Lee, K. P.; McLachlan, T.; Nishimura, Y.; Richard, E.; Okumura, K.; Labarga, L.; Fernandez, P.; Berkman, S.; Tanaka, H. A.; Tobayama, S.; Gustafson, J.; Kearns, E.; Raaf, J. L.; Stone, J. L.; Sulak, L. R.; Goldhaber, M.; Carminati, G.; Kropp, W. R.; Mine, S.; Weatherly, P.; Renshaw, A.; Smy, M. B.; Sobel, H. W.; Takhistov, V.; Ganezer, K. S.; Hartfiel, B. L.; Hill, J.; Keig, W. E.; Hong, N.; Kim, J. Y.; Lim, I. T.; Akiri, T.; Himmel, A.; Scholberg, K.; Walter, C. W.; Wongjirad, T.; Ishizuka, T.; Tasaka, S.; Jang, J. S.; Learned, J. G.; Matsuno, S.; Smith, S. N.; Hasegawa, T.; Ishida, T.; Ishii, T.; Kobayashi, T.; Nakadaira, T.; Nakamura, K.; Oyama, Y.; Sakashita, K.; Sekiguchi, T.; Tsukamoto, T.; Suzuki, A. T.; Takeuchi, Y.; Bronner, C.; Hirota, S.; Huang, K.; Ieki, K.; Kikawa, T.; Minamino, A.; Murakami, A.; Nakaya, T.; Suzuki, K.; Takahashi, S.; Tateishi, K.; Fukuda, Y.; Choi, K.; Itow, Y.; Mitsuka, G.; Mijakowski, P.; Hignight, J.; Imber, J.; Jung, C. K.; Yanagisawa, C.; Wilking, M. J.; Ishino, H.; Kibayashi, A.; Koshio, Y.; Mori, T.; Sakuda, M.; Yamaguchi, R.; Yano, T.; Kuno, Y.; Tacik, R.; Kim, S. B.; Okazawa, H.; Choi, Y.; Nishijima, K.; Koshiba, M.; Suda, Y.; Totsuka, Y.; Yokoyama, M.; Martens, K.; Marti, Ll.; Vagins, M. R.; Martin, J. F.; de Perio, P.; Konaka, A.; Chen, S.; Zhang, Y.; Connolly, K.; Wilkes, R. J.

    2016-08-01

    We present a real-time supernova neutrino burst monitor at Super-Kamiokande (SK). Detecting supernova explosions by neutrinos in real time is crucial for giving a clear picture of the explosion mechanism. Since the neutrinos are expected to come earlier than light, a fast broadcasting of the detection may give astronomers a chance to make electromagnetic radiation observations of the explosions right at the onset. The role of the monitor includes a fast announcement of the neutrino burst detection to the world and a determination of the supernova direction. We present the online neutrino burst detection system and studies of the direction determination accuracy based on simulations at SK.

  4. Real-Time Supernova Neutrino Burst Monitor at Super-Kamiokande

    CERN Document Server

    Abe, K; Hayato, Y; Ikeda, M; Iyogi, K; Kameda, J; Kishimoto, Y; Miura, M; Moriyama, S; Nakahata, M; Nakano, Y; Nakayama, S; Sekiya, H; Shiozawa, M; Suzuki, Y; Takeda, A; Tanaka, H; Tomura, T; Ueno, K; Wendell, R A; Yokozawa, T; Irvine, T; Kajita, T; Kametani, I; Kaneyuki, K; Lee, K P; McLachlan, T; Nishimura, Y; Richard, E; Okumura, K; Labarga, L; Fernandez, P; Berkman, S; Tanaka, H A; Tobayama, S; Gustafson, J; Kearns, E; Raaf, J L; Stone, J L; Sulak, L R; Goldhaber, M; Carminati, G; Kropp, W R; Mine, S; Weatherly, P; Renshaw, A; Smy, M B; Sobel, H W; Takhistov, V; Ganezer, K S; Hartfiel, B L; Hill, J; Keig, W E; Hong, N; Kim, J Y; Lim, I T; Akiri, T; Himmel, A; Scholberg, K; Walter, C W; Wongjirad, T; Ishizuka, T; Tasaka, S; Jang, J S; Learned, J G; Matsuno, S; Smith, S N; Hasegawa, T; Ishida, T; Ishii, T; Kobayashi, T; Nakadaira, T; Nakamura, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Suzuki, A T; Takeuchi, Y; Bronner, C; Hirota, S; Huang, K; Ieki, K; Kikawa, T; Minamino, A; Murakami, A; Nakaya, T; Suzuki, K; Takahashi, S; Tateishi, K; Fukuda, Y; Choi, K; Itow, Y; Mitsuka, G; Mijakowski, P; Hignight, J; Imber, J; Jung, C K; Yanagisawa, C; Wilking, M J; Ishino, H; Kibayashi, A; Koshio, Y; Mori, T; Sakuda, M; Yamaguchi, R; Yano, T; Kuno, Y; Tacik, R; Kim, S B; Okazawa, H; Choi, Y; Nishijima, K; Koshiba, M; Suda, Y; Totsuka, Y; Yokoyama, M; Martens, K; Marti, Ll; Vagins, M R; Martin, J F; de Perio, P; Konaka, A; Chen, S; Zhang, Y; Connolly, K; Wilkes, R J

    2016-01-01

    We present a real-time supernova neutrino burst monitor at Super-Kamiokande (SK). Detecting supernova explosions by neutrinos in real time is crucial for giving a clear picture of the explosion mechanism. Since the neutrinos are expected to come earlier than light, a fast broadcasting of the detection may give astronomers a chance to make electromagnetic radiation observations of the explosions right at the onset. The role of the monitor includes a fast announcement of the neutrino burst detection to the world and a determination of the supernova direction. We present the online neutrino burst detection system and studies of the direction determination accuracy based on simulations at SK.

  5. Anomalies in low-energy Gamma-Ray Burst spectra with the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Tierney, Dave; Preece, Robert D; Fitzpatrick, Gerard; Foley, Suzanne; Guiriec, Sylvain; Bissaldi, Elisabetta; Briggs, Michael S; Burgess, J Michael; Connaughton, Valerie; Goldstein, Adam; Greiner, Jochen; Gruber, David; Kouveliotou, Chryssa; McGlynn, Sinead; Paciesas, William S; Pelassa, Veronique; von Kienlin, Andreas

    2013-01-01

    A Band function has become the standard spectral function used to describe the prompt emission spectra of gamma-ray bursts (GRBs). However, deviations from this function have previously been observed in GRBs detected by BATSE and in individual GRBs from the \\textit{Fermi} era. We present a systematic and rigorous search for spectral deviations from a Band function at low energies in a sample of the first two years of high fluence, long bursts detected by the \\textit{Fermi} Gamma-Ray Burst Monitor (GBM). The sample contains 45 bursts with a fluence greater than 2$\\times10^{-5}$ erg / cm$^{2}$ (10 - 1000 keV). An extrapolated fit method is used to search for low-energy spectral anomalies, whereby a Band function is fit above a variable low-energy threshold and then the best fit function is extrapolated to lower energy data. Deviations are quantified by examining residuals derived from the extrapolated function and the data and their significance is determined via comprehensive simulations which account for the ...

  6. Remote monitoring within the framework of rock burst prevention. Fernueberwachung in der Gebirgsschlagverhuetung

    Energy Technology Data Exchange (ETDEWEB)

    Hahnekamp, H.G.; Koenig, W.; Kuzia, M.

    1991-12-12

    The DMT Institute for Rock Control and Backfilling of Cavities has developed a technically simple remote monitoring system for use within the framwork of rock burst prevention. With this system coal faces can be continuously monitored even under difficult underground conditions without serious operating problems. For the monitoring the variables measured underground, viz. rock pressure, rock movement and deformation of test boreholes, are transmitted via the telecommunication network of the colliery to a computer on the surface, where they are evaluated online with regard to recognition of a rock burst hazard. Display of the actual monitoring situation on the computer screen permits immediate initiation of safety measures in the event of danger. (orig.).

  7. Time Resolved Spectroscopy of SGR J1550-5418 Bursts Detected with Fermi/Gamma-Ray Burst Monitor

    Science.gov (United States)

    Younes, G.; Kouveliotou, C.; van der Horst, A. J.; Baring, M. G.; Granot, J.; Watts, A. L.; Bhat, P. N.; Collazzi, A.; Gehrels, N.; Gorgone, N.; Göğüş, E.; Gruber, D.; Grunblatt, S.; Huppenkothen, D.; Kaneko, Y.; von Kienlin, A.; van der Klis, M.; Lin, L.; Mcenery, J.; van Putten, T.; Wijers, R. A. M. J.

    2014-04-01

    We report on a time-resolved spectroscopy of the 63 brightest bursts of SGR J1550-5418, detected with the Fermi/Gamma-ray Burst Monitor during its 2008-2009 intense bursting episode. We performed spectral analysis down to 4 ms timescales to characterize the spectral evolution of the bursts. Using a Comptonized model, we find that the peak energy, E peak, anti-correlates with flux, while the low-energy photon index remains constant at ~ - 0.8 up to a flux limit F ≈ 10-5 erg s-1 cm-2. Above this flux value, the E peak-flux correlation changes sign, and the index positively correlates with the flux reaching ~1 at the highest fluxes. Using a two blackbody model, we find that the areas and fluxes of the two emitting regions correlate positively. Further, we study here for the first time the evolution of the temperatures and areas as a function of flux. We find that the area-kT relation follows the lines of constant luminosity at the lowest fluxes, R 2vpropkT -4, with a break at the higher fluxes (F > 10-5.5 erg s-1 cm-2). The area of the high-kT component increases with the flux while its temperature decreases, which we interpret as being due to an adiabatic cooling process. The area of the low-kT component, on the other hand, appears to saturate at the highest fluxes, toward R max ≈ 30 km. Assuming that crust quakes are responsible for soft gamma repeater (SGR) bursts and considering R max as the maximum radius of the emitting photon-pair plasma fireball, we relate this saturation radius to a minimum excitation radius of the magnetosphere, and we put a lower limit on the internal magnetic field of SGR J1550-5418, B int >~ 4.5 × 1015 G.

  8. Do the Fermi Gamma-Ray Burst Monitor and Swift Burst Alert Telescope see the Same Short Gamma-Ray Bursts?

    CERN Document Server

    Burns, Eric; Zhang, Bin-Bin; Lien, Amy; Briggs, Michael S; Goldstein, Adam; Pelassa, Veronique; Troja, Eleonora

    2015-01-01

    Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. We find that the Swift BAT triggers on weaker SGRBs than Fermi GBM, providing they occur close to the center of the BAT field-of-view, and that the Fermi GBM SGRB detection threshold remains flatter across its field-of-view. Overall, these effects combine to give the instruments the same average sensitivity, and account for the SGRBs that trigger one instrument but not the other. We do not find any evidence that the BAT and...

  9. Continued Radio Monitoring of the Gamma Ray Burst 991208

    CERN Document Server

    Galama, T J; Sari, R; Berger, E; Taylor, G B; Kulkarni, S R

    2003-01-01

    We present radio observations of the afterglow of the bright gamma-ray burst GRB 991208 at frequencies of 1.4, 4.9 and 8.5 GHz, taken between two weeks and 300 days after the burst. The well-sampled radio light curve at 8.5 GHz shows that the peak flux density peaked about 10 days after the burst and decayed thereafter as a power-law t^-1.07. This decay rate is more shallow than the optical afterglow with t^-2.2, which was measured during the first week. These late-time data are combined with extensive optical, millimeter and centimeter measurements and fitted to the standard relativistic blast wave model. In agreement with previous findings, we find that an isotropic explosion in a constant density or wind-blown medium cannot explain these broadband data without modifying the assumption of a single power-law slope for the electron energy distribution. A jet-like expansion provides a reasonable fit to the data. In this case, the flatter radio light curve compared to the optical may be due to emission from an ...

  10. Time resolved spectroscopy of SGR J1550–5418 bursts detected with Fermi/gamma-ray burst monitor

    Energy Technology Data Exchange (ETDEWEB)

    Younes, G. [Universities Space Research Association, 6767 Old Madison Pike, Suite 450, Huntsville, AL 35806 (United States); Kouveliotou, C.; Collazzi, A. [Astrophysics Office, ZP 12, NASA-Marshall Space Flight Center, Huntsville, AL 35812 (United States); Van der Horst, A. J.; Watts, A. L.; Huppenkothen, D.; Van der Klis, M.; Van Putten, T. [Astronomical Institute " Anton Pannekoek," University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Granot, J. [Department of Natural Sciences, The Open University of Israel, 1 University Road, P.O. Box 808, Raánana 43537 (Israel); Bhat, P. N.; Gorgone, N. [University of Alabama in Huntsville CSPAR, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Gehrels, N.; Mcenery, J. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Göğüş, E.; Kaneko, Y.; Lin, L. [Sabancı University, Orhanlı-Tuzla, İstanbul 34956 (Turkey); Gruber, D.; Von Kienlin, A. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, D-85748 Garching (Germany); Grunblatt, S. [University of Hawaii at Manoa, 2500 Campus Road, Honolulu, HI 96822 (United States); and others

    2014-04-10

    We report on a time-resolved spectroscopy of the 63 brightest bursts of SGR J1550–5418, detected with the Fermi/Gamma-ray Burst Monitor during its 2008-2009 intense bursting episode. We performed spectral analysis down to 4 ms timescales to characterize the spectral evolution of the bursts. Using a Comptonized model, we find that the peak energy, E {sub peak}, anti-correlates with flux, while the low-energy photon index remains constant at ∼ – 0.8 up to a flux limit F ≈ 10{sup –5} erg s{sup –1} cm{sup –2}. Above this flux value, the E {sub peak}–flux correlation changes sign, and the index positively correlates with the flux reaching ∼1 at the highest fluxes. Using a two blackbody model, we find that the areas and fluxes of the two emitting regions correlate positively. Further, we study here for the first time the evolution of the temperatures and areas as a function of flux. We find that the area–kT relation follows the lines of constant luminosity at the lowest fluxes, R {sup 2}∝kT {sup –4}, with a break at the higher fluxes (F > 10{sup –5.5} erg s{sup –1} cm{sup –2}). The area of the high-kT component increases with the flux while its temperature decreases, which we interpret as being due to an adiabatic cooling process. The area of the low-kT component, on the other hand, appears to saturate at the highest fluxes, toward R {sub max} ≈ 30 km. Assuming that crust quakes are responsible for soft gamma repeater (SGR) bursts and considering R {sub max} as the maximum radius of the emitting photon-pair plasma fireball, we relate this saturation radius to a minimum excitation radius of the magnetosphere, and we put a lower limit on the internal magnetic field of SGR J1550–5418, B {sub int} ≳ 4.5 × 10{sup 15} G.

  11. An assessment of burst strength distribution data for monitoring quality of condom stocks in developing countries.

    Science.gov (United States)

    Free, M J; Hutchings, J; Lubis, F; Natakusumah, R

    1986-03-01

    Laboratory tests were conducted on condoms to examine the changes that occur over time in indicators of condom burst strength, and to determine the relationship between laboratory-assessed condom burst strength and breakage during use in a developing country setting. Three groups of unaged condoms purchased directly from the manufacturer were used: one group exposed to UV light for 10 hours; one group exposed for five hours; and one group unexposed. A sample of each of these groups was tested according to ISO condom air burst test protocols. The remaining condoms were individually packaged in coded polyethylene bags for shipment to the developing country study site. Also used in the study was a group of condoms that had been aged for over 40 months under field conditions in a tropical climate; a sample from this group was tested by the ISO air burst test protocol and the remainder distributed to the study site. One-hundred-thirty Indonesian urban males participated in the double-blind study. Volunteers were not relying on the condom for contraceptive purposes. Each volunteer was given one individually packaged untreated condom, one condom from each treatment group, and four condoms aged in the field. Study participants were instructed to return all used condoms. Each condom that was returned after use was examined for breakage, and the unbroken condoms were subjected to an air inflation test to determine volume and pressure at burst. A comparison of the air burst volume data for a sample of unused and used condoms from the same treatment group indicates that most of the condoms that broke during use had air burst volumes below 11 liters. Therefore, a significant downward shift in the burst strength distribution as measured in the laboratory is likely to result in an increased breakage rate during use. A Condom Deterioration Index calculated from regular periodic testing of stored condom stocks is a convenient and sensitive means of monitoring trends in the

  12. Magnetar Bursts

    Science.gov (United States)

    Kouveliotou, Chryssa

    2014-01-01

    The Fermi/Gamma-ray Burst Monitor (GBM) was launched in June 2008. During the last five years the instrument has observed several hundreds of bursts from 8 confirmed magnetars and 19 events from unconfirmed sources. I will discuss the results of the GBM magnetar burst catalog, expand on the different properties of their diverse source population, and compare these results with the bursting activity of past sources. I will then conclude with thoughts of how these properties fit the magnetar theoretical models.

  13. Bubble, Burp, Bang! Self-organizing Cyclicity in Slug-driven Eruptions

    Science.gov (United States)

    Llewellin, E. W.; Del Bello, E.; Mathias, S.; Taddeucci, J.; Lane, S. J.; Scarlato, P.

    2011-12-01

    Strombolian volcanic activity is generally thought to be driven by the ascent and bursting of large slugs of magmatic gas; a similar slug-drive mechanism is likely to operate in geysers and some mud volcanoes. We present the results of field measurements, laboratory experiments and numerical modelling of the ascent and bursting of gas slugs. Our results quantify the physical controls on the development of overpressure in slug-driven eruptions and demonstrate that rhythmic eruptions - commonly observed in strombolian activity - can emerge as a consequence of the complex interplay between the evolving pressure in the slug, and the conditions at the vent and in the subsurface reservoir. We have conducted analogue experiments in which gas slugs ascend vertical pipes filled with various liquids. Our analogue conduits range in scale from 2cm diameter, 2m height, to 25cm diameter, 13m height, allowing us to investigate slug Reynolds numbers in the range 10-4 gas slug and the rheology of the liquid phase are the most influential parameters in controlling slug overpressure at bursting: larger slugs and higher liquid viscosity lead to more energetic eruptions. Based on our results, we develop a dimensionless analytical treatment which allows burst overpressure to be determined for slug-driven eruptions of all kinds. We compare our model predictions with field data from Stromboli volcano and find that our model can explain the entire spectrum of observed eruptive behaviour - from low-energy puffing, through normal strombolian eruptions, up to paroxysmal explosions - as manifestations of a single underlying physical process. We also develop a numerical model which determines the evolution, over time, of slug overpressure during ascent. We find that, when the vent is either constricted, or filled with a liquid possessing a yield stress, the ascending and expanding gas slug causes the liquid beneath it to flow back down the conduit and re-enter the subsurface reservoir. When the

  14. Indication of radio frequency interference (RFI) sources for solar burst monitoring in Malaysia

    Science.gov (United States)

    Hamidi, Z. S.; Abidin, Z. Z.; Ibrahim, Z. A.; Shariff, N. N. M.

    2012-06-01

    Apart of monitoring the Sun project, the Radio Frequency Interference (RFI) surveying in the region of (1-1200) MHz has been conducted. The main objective of this surveying is to test and qualify the potential of monitoring a continuous radio emission of Solar in Malaysia. This work is also an initiative of International Space Weather Initiative (ISWI) project where Malaysia is one of the country that participate a e-Callisto Spectrometer network in order to study the behavior of Solar radio burst in frequency of (45-800) MHz region which will be install in this October. Detail results will indicate the potential of monitoring a solar in Malaysia.

  15. Probing the Nature of Short Swift Bursts via Deep INTEGRAL Monitoring of GRB 050925

    Science.gov (United States)

    Sakamoto, T.; Barbier, L.; Barthelmy, S. D.; Cummings, J. R.; Fenimore, E. E.; Gehrels, N.; Krimm, H. A.; Markwardt, C. B.; Palmer, D. M.; Parsons, A. M.; Sato, G.; Stamatikos, M.; Tueller, J.

    2010-01-01

    We present results from Swift, XMM-Newton, and deep INTEGRAL monitoring in the region of GRB 050925. This short Swift burst is a candidate for a newly discovered soft gamma-ray repeater (SGR) with the following observational burst properties: 1) galactic plane (b=-0.1 deg) localization, 2) 150 msec duration, and 3) a blackbody rather than a simple power-law spectral shape (with a significance level of 97%). We found two possible X-ray counterparts of GRB 050925 by comparing the X-ray images from Swift XRT and XMM-Newton. Both X-ray sources show the transient behavior with a power-law decay index shallower than -1. We found no hard X-ray emission nor any additional burst from the location of GRB 050925 in approximately 5 Ms of INTEGRAL data. We discuss about the three BATSE short bursts which might be associated with GRB 050925, based on their location and the duration. Assuming GRB 050925 is associated with the H(sub II), regions (W 58) at the galactic longitude of 1=70 deg, we also discuss the source frame properties of GRB 050925.

  16. Rest-frame properties of gamma-ray bursts observed by the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Gruber, David

    2012-01-01

    In this talk I present the main spectral and temporal properties of Fermi/GBM gamma-ray bursts (GRBs) with known redshift. Key properties of these GRBs in the rest-frame of the progenitor are investigated to better understand the intrinsic nature of these events. The sample comprises 47 GRBs with measured redshift that were observed by GBM until May 2012. 39 sources belong to the long-duration population and 8 events were classified as short bursts. For all of these events we derive, where possible, the intrinsic peak energy in the {\

  17. Rest-frame properties of 32 gamma-ray bursts observed by the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Gruber, D; von Kienlin, A; Rau, A; Briggs, M S; Connaughton, V; Goldstein, A; van der Horst, A J; Nardini, M; Bhat, P N; Bissaldi, E; Burgess, J M; Chaplin, V L; Diehl, R; Fishman, G J; Fitzpatrick, G; Foley, S; Gibby, M H; Giles, M M; Guiriec, S; Kippen, R M; Kouveliotou, C; Lin, L; McBreen, S; Meegan, C A; E., F Olivares; Paciesas, W S; Preece, R D; Tierney, D; Wilson-Hodge, C

    2011-01-01

    Aims: In this paper we study the main spectral and temporal properties of gamma-ray bursts (GRBs) observed by Fermi/GBM. We investigate these key properties of GRBs in the rest-frame of the progenitor and test for possible intra-parameter correlations to better understand the intrinsic nature of these events. Methods: Our sample comprises 32 GRBs with measured redshift that were observed by GBM until August 2010. 28 of them belong to the long-duration population and 4 events were classified as short/hard bursts. For all of these events we derive, where possible, the intrinsic peak energy in the $\

  18. All-Sky Earth Occultation Observations with the Fermi Gamma Ray Burst Monitor

    CERN Document Server

    Wilson-Hodge, Colleen A; Bhat, P N; Briggs, M S; Chaplin, V; Connaughton, V; Camero-Arranz, A; Case, G; Cherry, M; Rodi, J; Finger, M H; Jenke, P; Haynes, R H

    2009-01-01

    Using the Gamma Ray Burst Monitor (GBM) on-board Fermi, we are monitoring the hard X-ray/soft gamma ray sky using the Earth occultation technique. Each time a source in our catalog enters or exits occultation by the Earth, we measure its flux using the change in count rates due to the occultation. Currently we are using CTIME data with 8 energy channels spanning 8 keV to 1 MeV for the GBM NaI detectors and spanning 150 keV to 40 MeV for the GBM BGO detectors. Our preliminary catalog consists of galactic X-ray binaries, the Crab Nebula, and active galactic nuclei. In addition, to Earth occultations, we have observed numerous occultations with Fermi's solar panels. We will present early results. Regularly updated results can be found on our website http://gammaray.nsstc.nasa.gov/gbm/science/occultation

  19. Slug control system; Sistema de controle de golfadas

    Energy Technology Data Exchange (ETDEWEB)

    Borges Filho, Alvaro de Miranda; Meira, Marco Antonio Alves de; Vaz, Celio Eduardo Martins [PETROBRAS, Macae, RJ (Brazil). Unidade de Negocios da Bacia de Campos

    2004-07-01

    Due to the characteristics of flow, gas can separate from oil in the pipelines and risers that link subsea manifolds to production offshore platforms, forming liquid and gas slugs in the production separator. Liquid slugs can cause overflow in the separators. Gas slugs can cause burning in the flare due to the limitation in the turbo-compressors acceleration. In both cases the consequences are loss of production or shut-downs. This paper presents a Slug Control System designed to attenuate severe gas and liquid flow variations. The system consist of a control valve installed in the separator inlet, transmitters, a controller, control algorithm and a monitoring station. This system is operating since October 2003 in a production offshore platform, in Campus Basin, Brazil, with excellent results, reducing the gas burning in 45% without oil production loss. (author)

  20. The First Fermi Gamma-ray Burst Monitor (GBM) Terrestrial Gamma-ray Flash (TGF) Catalog

    Science.gov (United States)

    Briggs, Michael; Connaughton, Valerie; Stanbro, Matthew; Zhang, Binbin; Bhat, Narayana; Fishman, Gerald; Roberts, Oliver; Fitzpatrick, Gerard; McBreen, Shelia; Grove, Eric; Chekhtman, Alexandre

    2015-04-01

    We present summary results from the first catalog of Terrestrial Gamma-ray Flashes (TGFs) detected with the Gamma-ray Burst Monitor (GBM) on the Fermi Space Telescope. The catalog reports parameters for over 2700 TGFs. Since the launch of Fermi in 2008 the TGF detection sensitivity of GBM has been improved several times, both in the flight software and in ground analysis. Starting in 2010 July individual photons were downloaded for portions of the orbits, enabling an off-line search that found weaker and shorter TGFs. Since 2012 November 26 this telemetry mode has been extended to continuous coverage. The TGF sample is reliable, with cosmic rays rejected using data both from Fermi GBM and from the Large Area Telescope on Fermi. The online catalog include times (UTC and solar), spacecraft geographic positions, durations, count intensities and Bayesian Block durations. The catalog includes separate tables for bright TGFs detected by the flight software and for Terrestrial Electron Beams (TEBs).

  1. Analysis of Precursors Prior to Rock Burst in Granite Tunnel Using Acoustic Emission and Far Infrared Monitoring

    Directory of Open Access Journals (Sweden)

    Zhengzhao Liang

    2013-01-01

    Full Text Available To understand the physical mechanism of the anomalous behaviors observed prior to rock burst, the acoustic emission (AE and far infrared (FIR techniques were applied to monitor the progressive failure of a rock tunnel model subjected to biaxial stresses. Images of fracturing process, temperature changes of the tunnel, and spatiotemporal serials of acoustic emission were simultaneously recorded during deformation of the model. The b-value derived from the amplitude distribution data of AE was calculated to predict the tunnel rock burst. The results showed that the vertical stress enhanced the stability of the tunnel, and the tunnels with higher confining pressure demonstrated a more abrupt and strong rock burst. Abnormal temperature changes around the wall were observed prior to the rock burst of the tunnel. Analysis of the AE events showed that a sudden drop and then a quiet period could be considered as the precursors to forecast the rock burst hazard. Statistical analysis indicated that rock fragment spalling occurred earlier than the abnormal temperature changes, and the abnormal temperature occurred earlier than the descent of the AE b-value. The analysis indicated that the temperature changes were more sensitive than the AE b-value changes to predict the tunnel rock bursts.

  2. Time-Resolved Spectroscopy of the 3 Brightest and Hardest Short Gamma-Ray Bursts Observed with the FGST Gamma-Ray Burst Monitor

    CERN Document Server

    Guiriec, Sylvain; Connaugthon, Valerie; Kara, Erin; Daigne, Frederic; Kouveliotou, Chryssa; van der Horst, Alexander J; Paciesas, William; Meegan, Charles A; Bhat, P N; Foley, Suzanne; Bissaldi, Elisabetta; Burgess, Michael; Chaplin, Vandiver; Diehl, Roland; Fishman, Gerald; Gibby, Melissa; Giles, Misty; Goldstein, Adam; Greiner, Jochen; Gruber, David; von Kienlin, Andreas; Kippen, Marc; McBreen, Sheila; Preece, Robert; Rau, Arne; Tierney, Dave; Wilson-Hodge, Colleen

    2010-01-01

    From July 2008 to October 2009, the Gamma-ray Burst Monitor (GBM) on board the Fermi Gamma-ray Space Telescope (FGST) has detected 320 Gamma-Ray Bursts (GRBs). About 20% of these events are classified as short based on their T90 duration below 2 s. We present here for the first time time-resolved spectroscopy at timescales as short as 2 ms for the three brightest short GRBs observed with GBM. The time-integrated spectra of the events deviate from the Band function, indicating the existence of an additional spectral component, which can be fit by a power-law with index ~-1.5. The time-integrated Epeak values exceed 2 MeV for two of the bursts, and are well above the values observed in the brightest long GRBs. Their Epeak values and their low-energy power-law indices ({\\alpha}) confirm that short GRBs are harder than long ones. We find that short GRBs are very similar to long ones, but with light curves contracted in time and with harder spectra stretched towards higher energies. In our time-resolved spectrosco...

  3. Improved limits on sterile neutrino dark matter using full-sky Fermi Gamma-ray Burst Monitor data

    NARCIS (Netherlands)

    K.C.Y. Ng; S. Horiuchi; J.M. Gaskins; M. Smith; R. Preece

    2015-01-01

    A sterile neutrino of similar to keV mass is a well-motivated dark matter candidate. Its decay generates an x-ray line that offers a unique target for x-ray telescopes. For the first time, we use the Gamma-ray Burst Monitor (GBM) onboard the Fermi Gamma-Ray Space Telescope to search for sterile neut

  4. Passive slug mitigation by applying wavy pipes

    OpenAIRE

    Xing, Lanchang

    2011-01-01

    This work is to develop a passive slug mitigation technique based on a novel flow conditioner, wavy pipe, through laboratory experiment and numerical simulation. The wavy pipe has been applied to two types of slug flows: severe slugging in pipeline/riser systems and hydrodynamic slug flow in horizontal pipelines. The experiment of severe slugging mitigation was conducted on the 2” and 4” pipeline/riser systems in the Three-Phase Test Facility in PSE (Process Systems Engineer...

  5. ALFABURST: A realtime fast radio burst monitor for the Arecibo telescope

    CERN Document Server

    Chennamangalam, Jayanth; MacMahon, David; Armour, Wes; Cobb, Jeff; Lorimer, Duncan; Rajwade, Kaustubh; Siemion, Andrew; Werthimer, Dan; Williams, Christopher

    2015-01-01

    Fast radio bursts (FRBs) constitute an emerging class of fast radio transient whose origin continues to be a mystery. Realizing the importance of increasing coverage of the search parameter space, we have designed, built, and deployed a realtime monitor for FRBs at the 305-m Arecibo radio telescope. Named 'ALFABURST', it is a commensal instrument that is triggered whenever the 1.4 GHz seven-beam Arecibo $L$-Band Feed Array (ALFA) receiver commences operation. The ongoing commensal survey we are conducting using ALFABURST has an instantaneous field of view of 0.02 sq. deg. within the FWHM of the beams, with the realtime software configurable to use up to 300 MHz of bandwidth. We search for FRBs with dispersion measure up to 2560 cm$^{-3}$ pc and pulse widths ranging from 0.128 ms to 16.384 ms. Commissioning observations performed over the past few months have demonstrated the capability of the instrument in detecting single pulses from known pulsars. In this paper, I describe the instrument and the associated ...

  6. Quasi -Periodic Pulsations in Solar Flares: new clues from the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Gruber, D; Bissaldi, E; Briggs, M S; Connaughton, V; Greiner, J; van der Horst, A J; Kanbach, G; Rau, A; Bhat, P N; Diehl, R; von Kienlin, A; Kippen, R M; Meegan, C A; Paciesas, W S; Preece, R D; Wilson-Hodge, C

    2011-01-01

    In the last four decades it has been observed that solar flares show quasi-periodic pulsations (QPPs) from the lowest, i.e. radio, to the highest, i.e. gamma-ray, part of the electromagnetic spectrum. To this day, it is still unclear which mechanism creates such QPPs. In this paper, we analyze four bright solar flares which show compelling signatures of quasi-periodic behavior and were observed with the Gamma-Ray Burst Monitor (\\gbm) onboard the Fermi satellite. Because GBM covers over 3 decades in energy (8 keV to 40 MeV) it can be a key instrument to understand the physical processes which drive solar flares. We tested for periodicity in the time series of the solar flares observed by GBM by applying a classical periodogram analysis. However, contrary to previous authors, we did not detrend the raw light curve before creating the power spectral density spectrum (PSD). To assess the significance of the frequencies we made use of a method which is commonly applied for X-ray binaries and Seyfert galaxies. This...

  7. The Fermi Gamma-ray Burst Monitor (GBM) Terrestrial Gamma-ray Flash (TGF) Catalog

    Science.gov (United States)

    Stanbro, M.; Briggs, M. S.; Roberts, O.; McBreen, S.; Bhat, N.; Fitzpatrick, G.

    2015-12-01

    We present results from the catalog of Terrestrial Gamma-ray Flashes (TGFs) detected with the Gamma-ray Burst Monitor (GBM) on the Fermi Gamma-ray Space Telescope. The first release, in January 2015, provided data on 2700 TGFs. Updates are extending the catalog at a rate of ~800 TGFs per year. The TGF sample is reliable, with cosmic rays rejected using data both from Fermi GBM and from the Large Area Telescope on Fermi. The online catalog include times (UTC and solar), spacecraft geographic positions, durations, count intensities and other Bayesian Block durations. The catalog includes separate tables for bright TGFs detected by the flight software and for Terrestrial Electron Beams (TEBs). In January 2016 additional data will be released online from correlating these TGFs with sferics detected by the World Wide Lightning Location Network (WWLLN). Maps of sferics in the vicinity of each TGF will be provided, as will the locations and times of sferics found to be associated with TGFs.

  8. Real-time monitoring of oxidative burst from single plant protoplasts using microelectrochemical sensors modified by platinum nanoparticles.

    Science.gov (United States)

    Ai, Feng; Chen, Hong; Zhang, Shu-Hui; Liu, Sheng-Yi; Wei, Fang; Dong, Xu-Yan; Cheng, Jie-Ke; Huang, Wei-Hua

    2009-10-15

    Oxidative bursts from plants play significant roles in plant disease defense and signal transduction; however, it has not hitherto been investigated on individual living plant cells. In this article, we fabricated a novel sensitive electrochemical sensor based on electrochemical deposition of Pt nanoparticles on the surface of carbon fiber microdisk electrodes via a nanopores containing polymer matrix, Nafion. The numerous hydrophilic nanochannels in the Nafion clusters coated on the electrode surface served as the molecular template for the deposition and dispersion of Pt, which resulted in the uniform construction of small Pt nanoparticles. The novel sensor displayed a high sensitivity for detection of H(2)O(2) with a detection limit of 5.0 x 10(-9) M. With the use of this microelectrochemical sensor, the oxidative burst from individual living plant protoplasts have been real-time monitored for the first time. The results showed that oxidative burst from single protoplasts triggered by a pathogen analogue were characterized by quanta release with a large number of "transient oxidative microburst" events, and protoplasts from the transgenic plants biologically displayed better disease-resistance and showed a distinguished elevation and longer-lasting oxidative burst.

  9. A Glue from Slug Slime?

    Science.gov (United States)

    Buttemer, Helen A.

    2009-01-01

    "Yuuuck!" "Gross!" "Cool!" The response to slugs is never indifference. These slimy creatures are perfect for captivating students' imagination and curiosity, and they are ideal subjects to introduce investigative science. This article describes a classroom activity in which students design a research investigation to answer the question: "Is slug…

  10. Gas slug ascent in a stratified magma: Implications of flow organisation and instability for Strombolian eruption dynamics

    Science.gov (United States)

    Capponi, A.; James, M. R.; Lane, S. J.

    2016-02-01

    The canonical Strombolian paradigm of a gas slug ascending and bursting in a homogeneous low-viscosity magma cannot explain the complex details in eruptive dynamics recently revealed by field measurements and textural and geochemical analyses. Evidence points to the existence of high-viscosity magma at the top of the conduit of Strombolian-type volcanoes, acting as a plug. Here, new experiments detail the range of flow configurations that develop during the ascent and burst of a slug through rheologically stratified magma within a conduit. End-member scenarios of a tube fully filled with either high- or low-viscosity liquid bracket three main flow configurations: (1) a plug sufficiently large to fully accommodate an ascending gas slug; (2) A plug that can accommodate the intrusion of low-viscosity liquid driven by the gas expansion, but not all the slug volume, so the slug bursts with the nose in the plug whilst the base is still in the low-viscosity liquid; (3) Gas expansion is sufficient to drive the intrusion of low-viscosity liquid through the plug, with the slug bursting in the low-viscosity layer emplaced dynamically above the plug. We show that the same flow configurations are viable at volcanic-scale through a new experimentally-validated 1D model and 3D computational fluid dynamic simulations. Applied to Stromboli, our results demonstrate that the key parameters controlling the transition between each configuration are gas volume, plug thickness and plug viscosity. The flow processes identified include effective dynamic narrowing and widening of the conduit, instabilities within the falling magma film, transient partial and complete blockage of the conduit, and slug disruption. These complexities influence eruption dynamics and vigour, promoting magma mingling and resulting in pulsatory release of gas.

  11. High-resolution slug testing.

    Science.gov (United States)

    Zemansky, G M; McElwee, C D

    2005-01-01

    The hydraulic conductivity (K) variation has important ramifications for ground water flow and the transport of contaminants in ground water. The delineation of the nature of that variation can be critical to complete characterization of a site and the planning of effective and efficient remedial measures. Site-specific features (such as high-conductivity zones) need to be quantified. Our alluvial field site in the Kansas River valley exhibits spatial variability, very high conductivities, and nonlinear behavior for slug tests in the sand and gravel aquifer. High-resolution, multilevel slug tests have been performed in a number of wells that are fully screened. A general nonlinear model based on the Navier-Stokes equation, nonlinear frictional loss, non-Darcian flow, acceleration effects, radius changes in the wellbore, and a Hvorslev model for the aquifer has been used to analyze the data, employing an automated processing system that runs within the Excel spreadsheet program. It is concluded that slug tests can provide the necessary data to identify the nature of both horizontal and vertical K variation in an aquifer and that improved delineation or higher resolution of K structure is possible with shorter test intervals. The gradation into zones of higher conductivity is sharper than seen previously, and the maximum conductivity observed is greater than previously measured. However, data from this project indicate that well development, the presence of fines, and the antecedent history of the well are important interrelated factors in regard to slug-test response and can prevent obtaining consistent results in some cases.

  12. Modeling cross-hole slug tests in an unconfined aquifer

    Science.gov (United States)

    Malama, Bwalya; Kuhlman, Kristopher L.; Brauchler, Ralf; Bayer, Peter

    2016-09-01

    A modified version of a published slug test model for unconfined aquifers is applied to cross-hole slug test data collected in field tests conducted at the Widen site in Switzerland. The model accounts for water-table effects using the linearized kinematic condition. The model also accounts for inertial effects in source and observation wells. The primary objective of this work is to demonstrate applicability of this semi-analytical model to multi-well and multi-level pneumatic slug tests. The pneumatic perturbation was applied at discrete intervals in a source well and monitored at discrete vertical intervals in observation wells. The source and observation well pairs were separated by distances of up to 4 m. The analysis yielded vertical profiles of hydraulic conductivity, specific storage, and specific yield at observation well locations. The hydraulic parameter estimates are compared to results from prior pumping and single-well slug tests conducted at the site, as well as to estimates from particle size analyses of sediment collected from boreholes during well installation. The results are in general agreement with results from prior tests and are indicative of a sand and gravel aquifer. Sensitivity analysis show that model identification of specific yield is strongest at late-time. However, the usefulness of late-time data is limited due to the low signal-to-noise ratios.

  13. Modeling cross-hole slug tests in an unconfined aquifer

    CERN Document Server

    Malama, Bwalya; Brauchler, Ralf; Bayer, Peter

    2016-01-01

    A modified version of a published slug test model for unconfined aquifers is applied to cross-hole slug test data collected in field tests conducted at the Widen site in Switzerland. The model accounts for water-table effects using the linearised kinematic condition. The model also accounts for inertial effects in source and observation wells. The primary objective of this work is to demonstrate applicability of this semi-analytical model to multi-well and multi-level pneumatic slug tests. The pneumatic perturbation was applied at discrete intervals in a source well and monitored at discrete vertical intervals in observation wells. The source and observation well pairs were separated by distances of up to 4 m. The analysis yielded vertical profiles of hydraulic conductivity, specific storage, and specific yield at observation well locations. The hydraulic parameter estimates are compared to results from prior pumping and single-well slug tests conducted at the site, as well as to estimates from particle size ...

  14. Detection of Gas Slugs in Heat Pipes

    Science.gov (United States)

    Jones, J. A.

    1985-01-01

    Temperature sensing system detects presence of gas slugs in heat pipes. System designed for operation between zero and 70 degrees C and detects noncondensable pockets of gas that result from decomposition of ammonia cooling fluid. Slugs 1 in. (25mm) in length detected.

  15. Compton scattering in terrestrial gamma-ray flashes detected with the Fermi gamma-ray burst monitor

    CERN Document Server

    Fitzpatrick, Gerard; McBreen, Sheila; Briggs, Michael S; Foley, Suzanne; Tierney, David; Chaplin, Vandiver L; Connaughton, Valerie; Stanbro, Matthew; Xiong, Shaolin; Dwyer, Joseph; Fishman, Gerald J; Roberts, Oliver J; von Kienlin, Andreas

    2015-01-01

    Terrestrial gamma-ray flashes (TGFs) are short intense flashes of gamma rays associated with lightning activity in thunderstorms. Using Monte Carlo simulations of the relativistic runaway electron avalanche (RREA) process, theoretical predictions for the temporal and spectral evolution of TGFs are compared to observations made with the Gamma-ray Burst Monitor (GBM) on board the Fermi Gamma-ray Space Telescope. Assuming a single source altitude of 15 km, a comparison of simulations to data is performed for a range of empirically chosen source electron variation time scales. The data exhibit a clear softening with increased source distance, in qualitative agreement with theoretical predictions. The simulated spectra follow this trend in the data, but tend to underestimate the observed hardness. Such a discrepancy may imply that the basic RREA model is not sufficient. Alternatively, a TGF beam that is tilted with respect to the zenith could produce an evolution with source distance that is compatible with the da...

  16. Investigation of 300 Area slug pickling operation

    Energy Technology Data Exchange (ETDEWEB)

    Corlett, R.F.

    1955-08-03

    The recent modernization program for the 300 area metal preparation process has included installation of automatic spray pickling machines. Operative problems have accompanied start-up of the new machine including too rapid reoxidation of slugs leaving the pickle operation. Numerous slugs have had to be repickled with consequent interruption to canning operations. Investigations were conducted in cooperation with Coatings and Corrosion Unit, Fuel Technology Sub-Section and Process Improvement Unit, Metal Preparation Section, to obtain basis information about slug oxide removal and reoxidation. Findings and conclusions from the investigation are presented in this document.

  17. Terrestrial Gamma-ray Flash (TGF) Observations with the Gamma-ray Burst Monitor on the Fermi Observatory

    Science.gov (United States)

    Fishman, Gerald J.

    2009-01-01

    Terrestrial Gamma-ray Flashes (TGFs) have now been detected with four different orbiting spacecraft. The latest observations are being made with the scintillation detectors of Gamma-ray Burst Monitor (GBM) on the Fermi Gamma-ray Space Telescope Observatory (Fermi). Although this experiment was designed and optimized for the observation of cosmic gamma-ray bursts (GRBs), it has unprecedented capabilities for TGF observations, surpassing those of the experiment that discovered TGFs, the BATSE experiment on the Compton Gamma-ray Observatory. Launched in June 2008 from the Kennedy Space Center, the Fermi-GBM has been detecting about one TGF every four weeks. The thick bismuth germinate (BGO) scintillation detectors of the GBM have now observed photon energies from TGFs at energies up to approx.40 MeV. Individual photons are detected with an absolute timing accuracy of 2 microsec. Unlike the BATSE instrument, the GBM data system allows higher counting rates to be recorded and deadtime characteristics are well-known and correctable; thus the saturation effects seen with BATSE are avoided. TGF pulses as narrow as approx.0.1ms have been observed with the GBM. Like BATSE (and unlike RHESSI) an on-board trigger is required to detect TGFs. The minimum time window for this trigger is 16ms. A trigger window this wide greatly reduces the number of detected TGFs, since they most often have a much shorter duration than this window, thus reducing the signal-to-background. New on-board trigger algorithms based on detected photon energies are about to be implemented; this should increase the number of TGF triggers. High-energy spectra from TGFs observed with Fermi-GBM will be described.

  18. Shell tension forces propel Dictyostelium slugs forward

    International Nuclear Information System (INIS)

    The Dictyostelium slug is an excellent model system for studying collective movements, as it is comprised of about 105 cells all moving together in the same direction. It still remains unclear how this movement occurs and what the physical mechanisms behind it are. By applying our recently developed 3D traction force microscopy, we propose a simple explanation for slug propulsion. Most of the forces are exerted by the sheath surrounding the slug. This secreted shell is under a rather uniform tension (around 50 mN m−1) and will give rise to a tissue under pressure. Finally, we propose that this pressure will naturally push the slug tip forwards if a gradient of shell mechanical properties takes place in the very anterior part of the raised tip. (paper)

  19. Shell tension forces propel Dictyostelium slugs forward.

    Science.gov (United States)

    Rieu, Jean-Paul; Delanoë-Ayari, Hélène

    2012-12-01

    The Dictyostelium slug is an excellent model system for studying collective movements, as it is comprised of about 10(5) cells all moving together in the same direction. It still remains unclear how this movement occurs and what the physical mechanisms behind it are. By applying our recently developed 3D traction force microscopy, we propose a simple explanation for slug propulsion. Most of the forces are exerted by the sheath surrounding the slug. This secreted shell is under a rather uniform tension (around 50 mN m(-1)) and will give rise to a tissue under pressure. Finally, we propose that this pressure will naturally push the slug tip forwards if a gradient of shell mechanical properties takes place in the very anterior part of the raised tip.

  20. Monitoring the burst-out of Enteromorpha prolifera in the Yellow Sea of China

    Science.gov (United States)

    Li, Haiying; Peng, Hongchun; Zhang, Hui; Huang, Chunlin

    2012-10-01

    In the eve of the Beijing Olympics Games, Qingdao in China, as the host city of OSC of Beijing 2008 Olympic Games, was surrounded by Enteromorpha prolifera, which was followed with interest by whole China and the world. The Enteromorpha often comes from other ocean, monitoring the drifting path of the Enteromorpha will become very important.The Study area is mainly the Yellow Sea. And the data sources are Terra MODIS 1B images from 2000-2010 years. The data preprocessing include BOW-TIE processing, image registration, clip, merge, and masking. And the NDVI was selected as the index of derived Enteromorpha prolifera information, to get the range of Enteromorpha prolifera, and get that of dynamic change with time, and monitor the drifting path of the Enteromorpha.

  1. Pulse properties of terrestrial gamma-ray flashes detected by the Fermi Gamma-Ray Burst Monitor

    CERN Document Server

    Foley, Suzanne; Briggs, Michael S; Connaughton, Valerie; Tierney, David; McBreen, Sheila; Dwyer, Joseph; Chaplin, Vandiver L; Bhat, P Narayana; Byrne, David; Cramer, Eric; Fishman, Gerald J; Xiong, Shaolin; Greiner, Jochen; Kippen, R Marc; Meegan, Charles A; Paciesas, William S; Preece, Robert D; von Kienlin, Andreas; Wilson-Hodge, Colleen

    2015-01-01

    The Gamma-ray Burst Monitor (GBM) on board the Fermi Gamma-ray Space Telescope has triggered on over 300 terrestrial gamma-ray flashes (TGFs) since its launch in June 2008. With 14 detectors, GBM collects on average ~100 counts per triggered TGF, enabling unprecedented studies of the time profiles of TGFs. Here we present the first rigorous analysis of the temporal properties of a large sample of TGFs (278), including the distributions of the rise and fall times of the individual pulses and their durations. A variety of time profiles are observed with 19 of TGFs having multiple pulses separated in time and 31 clear cases of partially overlapping pulses. The effect of instrumental dead time and pulse pileup on the temporal properties are also presented. As the observed gamma ray pulse structure is representative of the electron flux at the source, TGF pulse parameters are critical to distinguish between relativistic feedback discharge and lightning leader models. We show that at least 67% of TGFs at satellite ...

  2. Suzaku Wide-band All-sky Monitor measurements of duration distributions of gamma-ray bursts

    Science.gov (United States)

    Ohmori, Norisuke; Yamaoka, Kazutaka; Ohno, Masanori; Sugita, Satoshi; Kinoshita, Ryuuji; Nishioka, Yusuke; Hurley, Kevin; Hanabata, Yoshitaka; Tashiro, Makoto S.; Enomoto, Junichi; Fujinuma, Takeshi; Fukazawa, Yasushi; Iwakiri, Wataru; Kawano, Takafumi; Kokubun, Motohide; Makishima, Kazuo; Matsuoka, Shunsuke; Nagayoshi, Tsutomu; Nakagawa, Yujin E.; Nakaya, Souhei; Nakazawa, Kazuhiro; Takahashi, Tadayuki; Takeda, Sawako; Terada, Yukikatsu; Urata, Yuji; Yabe, Seiya; Yasuda, Tetsuya; Yamauchi, Makoto

    2016-06-01

    We report on the T90 and T50 duration distributions and their relations with spectral hardness using 1464 gamma-ray bursts (GRBs), which were observed by the Suzaku Wide-band All-sky Monitor (WAM) from 2005 August 4 to 2010 December 29. The duration distribution is clearly bimodal in three energy ranges (50-120, 120-250, and 250-550 keV), but is unclear in the 550-5000 keV range, probably because of the limited sample size. The WAM durations decrease with energy according to a power-law index of -0.058(-0.034, +0.033). The hardness-duration relation reveals the presence of short-hard and long-soft GRBs. The short:long event ratio tends to be higher with increasing energy. We compared the WAM distribution with ones measured by eight other GRB instruments. The WAM T90 distribution is very similar to those of INTEGRAL/SPI-ACS and Granat/PHEBUS, and least likely to match the Swift/BAT distribution. The WAM short:long event ratio (0.25:0.75) is much different from Swift/BAT (0.08:0.92), but is almost the same as CGRO/BATSE (0.25:0.75). To explain this difference for BAT, we examined three effects: BAT trigger types, energy dependence of the duration, and detection sensitivity differences between BAT and WAM. As a result, we found that the ratio difference could be explained mainly by energy dependence including soft extended emissions for short GRBs and much better sensitivity for BAT which can detect weak/long GRBs. The reason for the same short:long event ratio for BATSE and WAM was confirmed by calculation using the trigger efficiency curve.

  3. Determination of slug permeability factor for pressure drop prediction of slug flow pneumatic conveying

    Institute of Scientific and Technical Information of China (English)

    Shengming Tan; Kenneth C.Williams; Mark G.Jones; Tobias Krull

    2008-01-01

    Current models for pressure drop prediction of slug flow pneumatic conveying in a horizontal pipeline system assume some type of steady state conditions for prediction,which limits their capability for increased predictive accuracy relative to experimental data.This is partly because of the nature of slug flow pneumatic conveying system,which,as a dynamic system,never becomes stable.By utilising conservation of mass (airflow),a dynamic pressure analysis model is proposed on the basis of the derivative of the upstream pressure behaviour.The rate of air permeation through slug,one of the important factors in the conservation model,is expressed as a function of a slug permeability factor.Other factors such as slug velocity,slug length and the fraction of stationary layer were also considered.Several test materials were conveyed in single-slug tests to verify the proposed pressure drop model,showing good agreement between the model and experimental results.

  4. Lagrangian-Eulerian simulation of slugging fluidized bed

    Institute of Scientific and Technical Information of China (English)

    Guorong Wu; Jie Ouyang; Binxin Yang; Qiang Li; Fang Wang

    2012-01-01

    This work studies gas-solid slugging fluidized beds with Type-D particles,using two-dimensional simulations based on discrete element model (DEM).DEM performance is quantitatively validated by two commonly accepted correlations for determining slugging behavior.The voidage profiles simulated with bed height corresponding to Baeyens and Geldart (1974) correlation for onset of slugging demonstrate a transitional flow pattern from free bubbling to slugging.The present calculated values for the maximum slugging bed height are in good agreement with the correlation from Matsen et al.(1969).Simulations show that fluidized beds with Type-D particles can operate in the round-nosed slugging regime and also shows that wall slugs and square-nosed slugs tend to be formed with increase in superficial gas velocity and in bed height,respectively.

  5. Modeling of two-phase slug flow

    International Nuclear Information System (INIS)

    When gas and liquid flow in a pipe, over a range of flow rates, a flow pattern results in which sequences of long bubbles, almost filling the pipe cross section, are successively followed by liquid slugs that may contain small bubbles. This flow pattern, usually called slug flow, is encountered in numerous practical situations, such as in the production of hydrocarbons in wells and their transportation in pipelines; the production of steam and water in geothermal power plants; the boiling and condensation in liquid-vapor systems of thermal power plants; emergency core cooling of nuclear reactors; heat and mass transfer between gas and liquid in chemical reactors. This paper provides a review of two phase slug flow modeling

  6. Shotgun slug injuries: case report and literature review.

    Science.gov (United States)

    Gestring, M L; Geller, E R; Akkad, N; Bongiovanni, P J

    1996-04-01

    Shotguns are usually used to fire multiple pellets; however, they are capable of firing a single projectile in the form of a slug. Although rare, shotgun slug injuries are severe, producing wounds comparable to those inflicted by high-velocity weapons with the potential for even more tissue destruction because of the slug's size and mass. We report the first survivor of a close range shotgun slug injury, with a review of this weapon's unique projectile ballistics and the relevant literature. PMID:8614051

  7. Mitigation of terrain induced slugging using mixer devices

    NARCIS (Netherlands)

    Brasjen, B.J.; Veltin, J.; Hansen, J.H.

    2014-01-01

    The present work focuses on experimental evidence of slug mitigation via various devices. The slug mitigation potential of a number of mixers was tested using a laboratory scale air/water setup to compare their effect on the incoming slugs just upstream of the separator inlet. Dedicated methods and

  8. Clinicopathologic significance of slug expression in human intrahepatic cholangiocarcinoma

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To explore the expression and function of slug,a transcriptional repressor,in human intrahepatic cholangiocarcinoma(IHCC)and identify its role in IHCC progression.METHODS:Expression of slug was detected in 36 cases of IHCC and 12 cases of normal intrahepatic bile ducts and liver parenchyma by immunohistochemistry.The patients were divided into low slug expression group(< 20%of carcinoma cells stained)and high slug expression group(≥20%of carcinoma cells stained).Slug expression was correlated with clini...

  9. Computational modelling of slug flow in a capillary microreactor

    Science.gov (United States)

    Kashid, M. N.; Platte, F.; Agar, D. W.; Turek, S.

    2007-06-01

    The benefits of slug flow capillary microreactor exhibit the ability to adjust two individual transport mechanisms, i.e., convection inside the slug and diffusion between two consecutive slugs. The mass transfer rate is enhanced by internal circulation, which arises due to the shear between slug axis and continuous phase or capillary wall. The knowledge of circulation patterns within the slug plays an important role in the design of a capillary microreactor. Apart from this, well defined slug flow generation is a key activity in the development of methodology to study hydrodynamics and mass transfer. In the present paper we discuss computational fluid dynamics (CFD) modelling aspects of internal circulations (single phase) and slug flow generation (two-phase).

  10. Slug modeling with 1D two-fluid model

    International Nuclear Information System (INIS)

    Simulations of condensation-induced water hammer with one-dimensional two-fluid model requires explicit modeling of slug formation, slug propagation, and in some cases slug decay. Stratified flow correlations that are more or less well known in 1D two-fluid models, are crucial for accurate description of the initial phase of the slug formation and slug propagation. Slug formation means transition to other flow regime that requires different set of correlations. To use such two-fluid model for condensation induced water hammer simulations, a single slug must be explicitly recognized and captured. In the present work two cases of condensation-induced water hammer simulations performed with WAHA code, are described and discussed: injection of cold liquid into horizontal pipe filled with steam and injection of hot steam into horizontal pipe partially filled with cold liquid. (author)

  11. The Five Year Fermi/GBM Magnetar Burst Catalog

    NARCIS (Netherlands)

    A.C. Collazzi; C. Kouveliotou; A.J. van der Horst; G.A. Younes; Y. Kaneko; E. Göğüş; L. Lin; J. Granot; M.H. Finger; V.L. Chaplin; D. Huppenkothen; A.L. Watts; A. von Kienlin; M.G. Baring; D. Gruber; P.N. Bhat; M.H. Gibby; N. Gehrels; J. Mcenery; M. van der Klis; R.A.M.J. Wijers

    2015-01-01

    Since launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has detected many hundreds of bursts from magnetar sources. While the vast majority of these bursts have been attributed to several known magnetars, there is also a small sample of magnetar-like bursts of unknown origin. Here, we present

  12. Conducting Slug Tests in Mini-Piezometers

    Energy Technology Data Exchange (ETDEWEB)

    Fritz, Brad G.; Mackley, Rob D.; Arntzen, Evan V.

    2016-03-18

    Slug tests performed using mini-piezometers with diameters as small as 0.43 cm can provide a cost effective tool for hydraulic characterization. We evaluated the hydraulic properties of the apparatus in an infinite hydraulic conductivity environment and compared those results with field tests of mini-piezometers installed into locations with varying hydraulic properties. Based on our evaluation, slug tests conducted in mini-piezometers using the fabrication and installation approach described here are effective within formations where the hydraulic conductivity is less than 1 x 10-3 cm/s. While these constraints limit the potential application of this method, the benefits to this approach are that the installation, measurement and analysis is extremely cost effective, and the installation can be completed in areas where other (larger diameter) methods might not be possible. Additionally, this methodology could be applied to existing mini-piezometers previously installed for other purposes. Such analysis of existing installations could be beneficial in interpreting previously collected data (e.g. water quality data or hydraulic head data).

  13. A Burst to See

    Science.gov (United States)

    2008-04-01

    On 19 March, Nature was particularly generous and provided astronomers with the wealth of four gamma-ray bursts on the same day. But that was not all: one of them is the most luminous object ever observed in the Universe. Despite being located in a distant galaxy, billions of light years away, it was so bright that it could have been seen, for a brief while, with the unaided eye. ESO PR Photo 08a/08 ESO PR Photo 08a/08 The REM Telescope and TORTORA Camera Gamma-ray bursts (GRBs) are short flashes of energetic gamma-rays lasting from less than a second to several minutes. They release a tremendous quantity of energy in this short time making them the most powerful events since the Big Bang. It is now widely accepted that the majority of the gamma-ray bursts signal the explosion of very massive, highly evolved stars that collapse into black holes. Gamma-ray bursts, which are invisible to our eyes, are discovered by telescopes in space. After releasing their intense burst of high-energy radiation, they become detectable for a short while in the optical and in the near-infrared. This 'afterglow' fades very rapidly, making detailed analysis possible for only a few hours after the gamma-ray detection. This analysis is important in particular in order to determine the GRB's distance and, hence, intrinsic brightness. The gamma-ray burst GRB 080319B was detected by the NASA/STFC/ASI Swift satellite. "It was so bright that it almost blinded the Swift instruments for a while," says Guido Chincarini, Italian principal investigator of the mission. A bright optical counterpart was soon identified in the Boötes Constellation (the "Bear Driver" or "Herdsman"). A host of ground-based telescopes reacted promptly to study this new object in the sky. In particular, the optical emission was detected by a few wide-field cameras on telescopes that constantly monitor a large fraction of the sky, including the TORTORA camera in symbiosis with the 0.6-m REM telescope located at La Silla

  14. Toward A 3-D Picture of Hydraulic Conductivity With Multilevel Slug Tests

    Science.gov (United States)

    McElwee, C. D.; McElwee, C. D.; Ross, H. C.

    2001-12-01

    The GEMS (Geohydrologic Experiment and Monitoring Site) field area has been established (in the Kansas River valley near Lawrence, Kansas) for a variety of reasons relating to research and teaching in hydrogeology at the University of Kansas. Over 70 wells have been installed for various purposes. The site overlies an alluvial aquifer with a total thickness of about 70 feet. The water table is typically about 20 feet below the surface, giving a total saturated thickness of about 50 feet. The upper part of the aquifer is finer material consisting of silt and clay. Typically, the lower 35 feet of the aquifer is sand and gravel. A number of wells through out the site are fully screened through the sand and gravel aquifer. Some of these fully screened wells are larger diameters; however, most wells are constructed of 2 inch PVC casing. Slug tests are widely used in hydrogeology to measure hydraulic conductivity. Over the last several years we have been conducting research to improve the slug test method. We have previously reported the detailed structure of hydraulic conductivity that can be seen in a 5 inch well (McElwee and Zemansky, EOS, v. 80, no. 46, p. F397, 1999) at this site, using multilevel slug tests. The existing 2 inch, fully screened wells are spread out over the site and offer the opportunity for developing a 3-D picture of the hydraulic conductivity distribution. However, it is difficult to develop a system that allows multilevel slug tests to be done accurately and efficiently in a 2 inch well. This is especially true in regions of very high hydraulic conductivity, where the water velocity in the casing will be relatively high. The resistance caused by frictional forces in the equipment must be minimized and a model taking account of these forces must be used. We have developed a system (equipment, software, and technique) for performing multilevel slug tests in 2 inch wells. Some equipment configurations work better than others. The data that we have

  15. Follow the BAT: Monitoring Swift BAT FoV for Prompt Optical Emission from Gamma-ray Bursts

    CERN Document Server

    Ukwatta, T N; Dhuga, K S; Gehrels, N

    2011-01-01

    We investigate the feasibility of implementing a system called 'Follow the BAT' that will coordinate ground-based robotic optical and near infrared (NIR) telescopes to monitor the Swift BAT field-of-view (FoV). The system will optimize the monitoring locations in the BAT FoV based on individual robotic telescopes' location, FoV, sensitivity and local weather conditions. The aim is to perform coordinated BAT FoV monitoring by professional as well as amateur astronomers around the world. The scientific goal of the proposed system is to facilitate detection of prompt optical and NIR emission from GRBs, especially from short duration GRBs. We have performed a Monte Carlo simulation to investigate the feasibility of the project.

  16. X-ray bursts observed with JEM-X

    DEFF Research Database (Denmark)

    Brandt, Søren Kristian; Chenevez, Jérôme; Lund, Niels;

    2006-01-01

    We report on the search for X-ray bursts in the JEM-X X-ray monitor on INTEGRAL during the first two years of operations. More than 350 bursts from 25 different type-I X-ray burst sources were found.......We report on the search for X-ray bursts in the JEM-X X-ray monitor on INTEGRAL during the first two years of operations. More than 350 bursts from 25 different type-I X-ray burst sources were found....

  17. Two-phase slug flow in vertical and inclined tubes

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    Gas-liquid slug flow is investigated experimentally in vertical and inclined tubes.The non-invasive measuremnts of the gas-liquid slug flow are taken by using the EKTAPRO 1000 High Speed Motion Analyzer.The information on the velocity of the Talyor bubble,the size distribution of the dispersed bubbles in the liquid slugs and some characteristics of the liquid film around the Taylor bubble are obtained.The experimental results are in good agreement with the available data.

  18. An artificial neural network strategy for monitoring of gas/oil systems in slug flow pattern; Aplicacao de redes neurais artificiais no monitoramento do escoamento de sistemas gas/oleo em regime de golfadas

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Fernando H.B. [Universidade Tiradentes (UNIT), Aracaju, SE (Brazil). Instituto de Tecnologia e Pesquisa; Universidade Federal de Campina Grande (UFCG), PB (Brazil); Silva, Rosivania P.; Fortuny, Montserrat; Santos, Alexandre F. [Universidade Tiradentes (UNIT), Aracaju, (Brazil). Instituto de Tecnologia e Pesquisa; Nunes, Giovani C. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES)

    2008-07-01

    In the petroleum industry, the design of multiphase production systems requires an accurate estimation of the gas-oil ratio (GOR) in the transporting pipelines. However, existing GOR estimation methods are often inadequate in terms of desired accuracy and application range, due to the complex phase distributions and the wide range of fluid properties encountered in production operations. In this paper, the effectiveness of using artificial neural networks in determining GOR values is evaluated, proving to be a reasonable way to monitor this property during oil transportation. (author)

  19. Severe Slugging in Air-Water Hybrid Riser System

    OpenAIRE

    Gong, Jing; Yang, Zhiyuan; Ma, Liang; Ping WANG

    2014-01-01

    In the subsea pipeline gathering system, severe slugging flow is prone to occur. Severe slugging flow brings major threat to production and flow assurance in oil and gas industry due to periodical pressure oscillation and large liquid volume. Currently many researchers pay much more attention on L-shaped riser, catenaries, and S-shaped riser; little research has been made on hybrid riser, which is applied in the Africa West and Gulf of Mexico oil fields. Flow characteristics simulation for hy...

  20. Two-Phase Slug Flow Experiments with Viscous Liquids

    OpenAIRE

    Diaz, Mariana J.C.

    2016-01-01

    The challenges behind the multiphase transport of oil and gas mixtures are increasing as the oil and gas industry is moving towards production from non-conventional reservoirs and in remote locations. Transport of high viscosity fluids in long multiphase pipelines is a particular challenge. Previous experiments have shown that gas-liquid slug flow is a frequent two-phase flow pattern at high liquid viscosities. The slug flow regime is an unstable flow, which may lead to operati...

  1. Numerical Simulation of slug flow in a micro-channel

    OpenAIRE

    Carlson, Andreas

    2007-01-01

    Multiphase dynamics and characteristics of slug flow in micro channels are investigated computationally by means of advanced numerical simulation methods. Although, due to its importance in many engineering and biomedical applications, the topic has been studied previously, methods for robust and accurate simulation of slug flow remain elusive. Evaluation of current state-of-the-art Computational Multi Fluid Dynamics (CMFD) technology depicts deficiency with advanced computational methods (Vo...

  2. Fully developed turbulence in slugs of pipe flows

    Science.gov (United States)

    Cerbus, Rory; Liu, Chien-Chia; Sakakibara, Jun; Gioia, Gustavo; Chakraborty, Pinaki

    2015-11-01

    Despite over a century of research, transition to turbulence in pipe flows remains a mystery. In theory the flow remains laminar for arbitrarily large Reynolds number, Re. In practice, however, the flow transitions to turbulence at a finite Re whose value depends on the disturbance, natural or artificial, in the experimental setup. The flow remains in the transition state for a range of Re ~ 0 (1000) ; for larger Re the flow becomes fully developed. The transition state for Re > 3000 consists of axially segregated regions of laminar and turbulent patches. These turbulent patches, known as slugs, grow as they move downstream. Their lengths span anywhere between a few pipe diameters to the whole length of the pipe. Here we report Stereo Particle Image Velocimetry measurements in the cross-section of the slugs. Notwithstanding the continuous growth of the slugs, we find that the mean velocity and stress profiles in the slugs are indistinguishable from that of statistically-stationary fully-developed turbulent flows. Our results are independent of the length of the slugs. We contrast our results with the well-known work of Wygnanski & Champagne (1973), whose measurements, we argue, are insufficient to draw a clear conclusion regarding fully developed turbulence in slugs.

  3. The Double Firing Burst

    Science.gov (United States)

    2008-09-01

    this nearly head-on alignment to occur is only about once a decade," added his colleague Cristiano Guidorzi. GRB 080319B was detected by the NASA/STFC/ASI Swift satellite towards the constellation of Boötes, the "Herdsman". A host of ground-based telescopes reacted promptly to study this new object in the sky, including ESO's Very Large Telescope, which was the first to provide the distance of the object, 7.5 billion light-years. The visible light from the burst was detected by a handful of wide-field cameras worldwide that are mounted on telescopes constantly monitoring a large fraction of the sky. One of these was the TORTORA camera mounted on the 0.6-m REM telescope at ESO's La Silla Observatory (ESO 26/07). TORTORA's rapid imaging provides the most detailed look yet at the visible light associated with the initial blast of a gamma-ray burst. "We've been waiting a long time for this one," says TORTORA senior scientist Grigory Beskin of Russia's Special Astrophysical Observatory. The data collected simultaneously by TORTORA and the Swift satellite allowed astronomers to explain the properties of this burst.

  4. Slug catcher conceptual design as separator for heavy oil

    Energy Technology Data Exchange (ETDEWEB)

    Marquez, J.G.; Manzanilla, C.L.; Trujillo, J.N. [PDVSA Petroleos de Venezuela SA, Caracas (Venezuela, Bolivarian Republic of)

    2009-07-01

    Gas-liquid separation processes in heavy and extra heavy oil fields are typically performed using gravity conventional separators. However, the separation efficiency of the equipment depends on the operating conditions, appropriate design and properties of the fluids. Therefore, the separation efficiency is influenced by the liquid's high viscosity, low pressures and low gas flow rate that are present in heavy and extra heavy oil fields. These conditions increase the probability of slug flow formation through pipelines that cause operational problems, primarily in the separation process. Therefore, there is a need to design a gas-liquid separator that can handle viscous liquid, reduce the effects of slug flow and perform an efficient separation. The finger type slug catcher is a technology that can help to improve the gas-liquid separation. This paper presented an improvement in the methodology of Sarica et al. (1990), predicting the dimensions of finger type slug catcher for heavy oil fields. It was derived from the effect of the transition of stratified flow to non-stratified flow when the liquid phase was viscous and only considered slug flow characteristics under normal flow. Based on the improvement the required diameter and length of the finger were determined. This improvement was used to design a finger type slug catcher for heavy oil fields in Venezuela's Orinoco belt and an economic comparison against conventional separators was presented, demonstrating the finger type slug catcher to be more economical than the conventional separator. 17 refs., 4 tabs., 4 figs.

  5. Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Zhang Shaoyan

    2011-05-01

    Full Text Available Abstract Background Esophageal squamous cell carcinoma (ESCC is one of the most aggressive carcinomas of the gastrointestinal tract. We assessed the relevance of Slug in measuring the invasive potential of ESCC cells in vitro and in vivo in immunodeficient mice. Methods We utilized RNA interference to knockdown Slug gene expression, and effects on survival and invasive carcinoma were evaluated using a Boyden chamber transwell assay in vitro. We evaluated the effect of Slug siRNA-transfection and Slug cDNA-transfection on E-cadherin and Bcl-2 expression in ESCC cells. A pseudometastatic model of ESCC in immunodeficient mice was used to assess the effects of Slug siRNA transfection on tumor metastasis development. Results The EC109 cell line was transfected with Slug-siRNA to knockdown Slug expression. The TE13 cell line was transfected with Slug-cDNA to increase Slug expression. EC109 and TE13 cell lines were tested for the expression of apoptosis-related genes bcl-2 and metastasis-related gene E-cadherin identified previously as Slug targets. Bcl-2 expression was increased and E-cadherin was decreased in Slug siRNA-transfected EC109 cells. Bcl-2 expression was increased and E-cadherin was decreased in Slug cDNA-transfected TE13 cells. Invasion of Slug siRNA-transfected EC109 cells was reduced and apoptosis was increased whereas invasion was greater in Slug cDNA-transfected cells. Animals injected with Slug siRNA-transfected EC109 cells exhihited fewer seeded nodes and demonstrated more apoptosis. Conclusions Slug down-regulation promotes cell apoptosis and decreases invasion capability in vitro and in vivo. Slug inhibition may represent a novel strategy for treatment of metastatic ESCC.

  6. Experiments in a combined up stream downstream slug flow

    Directory of Open Access Journals (Sweden)

    Toledo-Velázquez M.

    2013-04-01

    Full Text Available Slug flow induced by the combination of a downstream and an upstream two phase flow is very common in the oil industry, mainly when the pipelines are installed on hilly terrains. This phenomenon can be dangerous for the equipment operation because it induces vibrations due to the slugs intermittent movement into the separators. A loop, where it is possible to change the flow conditions and the loop geometrical parameters as the length and inclination angle of the pipe sections was built. Instruments for slug detection and for measuring their characteristic parameters as hold up, frequency, length, and velocity were installed. Three conductive probes were used for the hold-up measurement in different points; all of them were designed, constructed, tested andcalibrated. Experimental runs for a set of four alternated sections upstream downstream W shaped pipe have been undertaken. The gas and liquid flow rates were selected in order to obtain stratified flow at the inlet, which is the condition to induce the severe slugging. The main conclusions of the experimental results analysis are presented in this paper. The Barnea's criterion has been compared against our experimental results, three slugging regions have been found.

  7. Secondary oil recovery process. [two separate surfactant slugs

    Energy Technology Data Exchange (ETDEWEB)

    Fallgatter, W.S.

    1969-01-14

    Oil recovery by two separate surfactant slugs is greater than for either one alone. One slug contains a surfactant(s) in either oil or water. The other slug contains surfactant(s) in thickened water. The surfactants are sodium petroleum sulfonate (Promor SS20), polyoxyethylene sorbitan trioleate (Tween 85), lauric acid diethanolamide (Trepoline L), and sodium tridecyl sulfate polyglycol ether (Trepenol S30T). The thickener is carboxymethyl cellulose (Hercules CMC 70-S Medium thickener) or polyvinyl alcohol (Du Pont Elvanol 50-42). Consolidated sandstone cores were flooded with water, followed with Hawes crude, and finally salt water (5 percent sodium chloride) which recovered about 67 percent of the crude. A maximum of 27.5 percent of the residual oil was recovered by surfactant(s) in oil or water followed by fresh water, then surfactant(s) plus thickener in water followed by fresh water. Either surfactant slug may be injected first. Individually, each of the surfactant slugs can recover from about 3 to 11 percent less residual oil than their total recovery when used consecutively.

  8. Modelling of slug dissipation and generation in a hilly-terrain pipeline

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, H.-Q.; El-Safran, E.M.; Jayawardena, S.S.; Redus, C.L.; Brill, J.P. [University of Tulsa (United States). Dept. of Petroleum Engineering

    2000-07-01

    Hilly-terrain pipelines consist of interconnected horizontal, uphill and downhill sections. Slug flow experiences a transition from one state to another as the pipe inclination angle changes. Normally, slugs dissipate if the upward inclination becomes smaller or the downward inclination becomes larger, and slug generation occurs vice versa. Appropriate prediction of the slug characteristics is crucial for the design of pipeline and downstream facilities. In this study, slug dissipation and generation in a valley pipeline configuration (horizontal-downhill-uphill-horizontal) were modeled by use of the method proposed by Zhang et al. The method was developed from the unsteady continuity and momentum equations for slug flow by considering the entire film zone as the control volume. Computed results are compared with experimental measurements at different gas-liquid flow rate combinations. Good agreement is observed for the change of slug body length to slug unit length ratio. (author)

  9. Simulation of horizontal slug-flow pneumatic conveying with kinetic theory

    Institute of Scientific and Technical Information of China (English)

    GU Zhengmeng; GUO Liejin

    2007-01-01

    Wavelike slug-flow is a representative flow type in horizontal pneumatic conveying.Kinetic theory was introduced to establish a 3D kinetic numerical model for wavelike slug gas-solid flow in this paper.Wavelike motion of particulate slugs in horizontal pipes was numerically investigated.The formation and motion process of slugs and settled layer were simulated.The characteristics of the flow,such as pressure drop,air velocity distribution,slug length and settled layer thickness,and the detailed changing characteristics of slug length and settled layer thickness with air velocity were obtained.The results indicate that kinetic theory can represent the physical characteristics of the non-suspension dense phase flow of wavelike slug pneumatic conveying.The experiment in this paper introduced a new idea for the numerical calculation of slug-flow pneumatic conveying.

  10. Stability of void fraction waves and bubble-slug transition

    International Nuclear Information System (INIS)

    The propagation of natural void fraction disturbances in a nitrogen-water flow has been studied, through the statistical analysis of conductivity probe signals, for void fractions ranging from .1 to .5 and including the bubble slug transition. The power spectral density function and the standard deviation of the void fraction signal have been computed for each probe, as well as the phase factor (wave velocity), the coherence function and the gain factor between each pair of consecutive probes as a function of frequency. For bubble flows, the results are in agreement with the results obtained by other authors. The transition from bubble to slug flow is related to void fraction wave instabilities, two kinds of instabilities occurring simultaneously: amplitude increase (gain factor > 1) and wave-breaking. A criterion for the flow-pattern transition between bubble and slug flow (maximum of standard deviation) is proposed

  11. A new general pressure-analysis procedure for slug tests

    Energy Technology Data Exchange (ETDEWEB)

    Peres, A.M.M.; Onur, M.; Reynolds, A.C. (Univ. of Tulsa, OK (United States))

    1993-12-01

    A new analysis procedure for determining formation flow capacity and skin factor from slug-test data is presented. The procedure arises from exact deconvolution equations that convert measured slug-test pressure data into equivalent pressure and pressure-derivative responses that would be obtained if the well were produced at a constant surface flow rate. The converted data then can be analyzed by use of existing wellbore-storage and skin type curves for the particular reservoir or well model represented by the field data. For cases where the slug test is short, the authors show that flow rate convolution can be incorporated to improve analysis reliability. The analysis procedures do not require direct knowledge of the sandface flow rate.

  12. Moraxella osloensis Gene Expression in the Slug Host Deroceras reticulatum

    Directory of Open Access Journals (Sweden)

    Sreevatsan Srinand

    2008-01-01

    Full Text Available Abstract Background The bacterium Moraxella osloensis is a mutualistic symbiont of the slug-parasitic nematode Phasmarhabditis hermaphrodita. In nature, P. hermaphrodita vectors M. osloensis into the shell cavity of the slug host Deroceras reticulatum in which the bacteria multiply and kill the slug. As M. osloensis is the main killing agent, genes expressed by M. osloensis in the slug are likely to play important roles in virulence. Studies on pathogenic interactions between bacteria and lower order hosts are few, but such studies have the potential to shed light on the evolution of bacterial virulence. Therefore, we investigated such an interaction by determining gene expression of M. osloensis in its slug host D. reticulatum by selectively capturing transcribed sequences. Results Thirteen M. osloensis genes were identified to be up-regulated post infection in D. reticulatum. Compared to the in vitro expressed genes in the stationary phase, we found that genes of ubiquinone synthetase (ubiS and acyl-coA synthetase (acs were up-regulated in both D. reticulatum and stationary phase in vitro cultures, but the remaining 11 genes were exclusively expressed in D. reticulatum and are hence infection specific. Mutational analysis on genes of protein-disulfide isomerase (dsbC and ubiS showed that the virulence of both mutants to slugs was markedly reduced and could be complemented. Further, compared to the growth rate of wild-type M. osloensis, the dsbC and ubiS mutants showed normal and reduced growth rate in vitro, respectively. Conclusion We conclude that 11 out of the 13 up-regulated M. osloensis genes are infection specific. Distribution of these identified genes in various bacterial pathogens indicates that the virulence genes are conserved among different pathogen-host interactions. Mutagenesis, growth rate and virulence bioassays further confirmed that ubiS and dsbC genes play important roles in M. osloensis survival and virulence, respectively

  13. Treatment of Uranium Slugs at the CEA Marcoule site - 12026

    International Nuclear Information System (INIS)

    The decladding units on the Marcoule nuclear site in southeast France were commissioned in the early 1960's to receive spent fuel cartridge for interim storage in pools and to prepare them for dissolution. After decladding, the uranium slugs were sent to the reprocessing plant for dissolution. The units were shut down in 1997. All the operational and process equipment was dismantled and transferred to the ANDRA waste repository between 1998 and 2001. During cleanup of the G2-G3 interim storage pool all the internal components (baskets and machinery) mounted on the civil engineering structures were cut up. In November 2007, a UNGG fuel slug in its aluminum cartridge was found at the bottom of the pool. Similarly, while iron slugs (used to control plutonium-producing reactors) were being sorted, five de-cladded uranium slugs were found between 2006 and 2008. As the processing facilities had already been dismantled, it was decided to send these fuel cartridges to a laboratory for dissolution. The project was to recover and condition the cartridge and slugs and transport them safely to the laboratory. This required the design of dedicated equipment due in particular to the high dose rate and pyro-phoricity hazard. The procedure also required safety clearance by the regulatory authorities for the operations within the facility and for the transport of radioactive materials. The cartridge was dissolved in May 2009, 18 months after it was discovered. Based on the experience acquired, the retrieval of the uranium slugs was completed in March 2011 after a year of preparation. (authors)

  14. Long liquid slugs in stratified gas/liquid flow in horizontal and slightly inclined pipes

    OpenAIRE

    Kadri, U.

    2009-01-01

    Long liquid slugs reaching several hundreds pipe diameter may appear when transporting gas and liquid in horizontal and near horizontal pipes. The long slugs cause system vibration and separation difficulties that may lead to operational failures. Identifying and predicting the time and length scales of slugging is important for gas and oil production technologies (e.g. for the design of offshore gas and oil pipelines and process facilities). Although mainly short hydrodynamic slugs (40 pipe ...

  15. On technology of electromagnetic radiation monitoring and treatment on rock burst in island working face%孤岛工作面冲击地压电磁辐射监测与治理技术研究

    Institute of Scientific and Technical Information of China (English)

    陈杨

    2014-01-01

    Taking the 1304 island working face in Yangcheng Mine as the example,based on the principle of electromagnetic radiation predicting rock burst and combining with support pres-sure distribution law in island working face,the paper analyzes the electromagnetic radiation mo-nitoring method and layout of measuring points.By using a variety of monitoring and treatment means centered on the electromagnetic radiation monitoring technology,a new technical method of monitoring and controlling for rock burst in island working face is established,including elec-tromagnetic radiation warning,rock burst hazard identification by drilling cuttings method,un-loading pressure by deep-hole blasting in coal and electromagnetic radiation testing the stress re-lease effect,which has obtained good effectiveness.%以阳城煤矿1304孤岛工作面为例,基于电磁辐射预测冲击地压原理,结合孤岛工作面支承压力分布规律,分析了电磁辐射监测方法及测点布置方式,通过采用以电磁辐射监测技术为核心的多种监测与治理手段,建立了电磁辐射预警→钻屑法危险识别→煤体深孔爆破卸压→电磁辐射卸压效果检验的孤岛工作面冲击地压危险监测与治理技术,并取得了良好的效果。

  16. Slug to churn transition analysis using wire-mesh sensor

    Science.gov (United States)

    H. F. Velasco, P.; Ortiz-Vidal, L. E.; Rocha, D. M.; Rodriguez, O. M. H.

    2016-06-01

    A comparison between some theoretical slug to churn flow-pattern transition models and experimental data is performed. The flow-pattern database considers vertical upward air-water flow at standard temperature and pressure for 50 mm and 32 mm ID pipes. A briefly description of the models and its phenomenology is presented. In general, the performance of the transition models is poor. We found that new experimental studies describing objectively both stable and unstable slug flow-pattern are required. In this sense, the Wire Mesh Sensor (WMS) can assist to that aim. The potential of the WMS is outlined.

  17. Internal Representation and Memory Formation of Odor Preference Based on Oscillatory Activities in a Terrestrial Slug

    Science.gov (United States)

    Sekiguchi, Tatsuhiko; Furudate, Hiroyuki; Kimura, Tetsuya

    2010-01-01

    The terrestrial slug "Limax" exhibits a highly developed ability to learn odors with a small nervous system. When a fluorescent dye, Lucifer Yellow (LY), is injected into the slug's body cavity after odor-taste associative conditioning, a group of neurons in the procerebral (PC) lobe, an olfactory center of the slug, is labeled by LY. We examined…

  18. Characterisation and monitoring of the Excavation Disturbed Zone (EDZ) in fractured gneisses of the Roselend underground laboratory: permeability measurements, transport property changes and related radon bursts

    Science.gov (United States)

    Wassermann, Jérôme; Sabroux, Jean-Christophe; Richon, Patrick; Pontreau, Sébastien; Guillon, Sophie; Pili, Eric

    2010-05-01

    pressure measurements between an obturated borehole and the tunnel is conducted to monitor the possible modifications of the transport properties of the EDZ due to hydraulical and/or mechanical sollicitations of the nearby Roselend reservoir lake. As radon level is controlled by emanation and transport path through the medium. The observed bursts of radon should be due to changes of the radon transport properties (Trique et al. 1999) of the EDZ. A correlation between the differential pressure variations and radon bursts is clearly observed. Radon bursts seem to be related to overpressure events that take place in the instrumented borehole. Which external sollicitations, hydraulical or mechanical, or both, induce such a behaviour? References Bossart, P., Meier, P. M., Moeri, A., Trick, T., and J.-C. Mayor (2002). Geological and hydraulic characterisation of the excavation disturbed zone in the Opalinus Clay of the Mont Terri Rock Laboratory, Engineering Geology, 66, 19-38. Dezayes, C., and T. Villemin (2002). Etat de la fracturation dans la galerie CEA de Roselend et analyse de la déformation cassante dans le massif du Méraillet, technical report, Lab. de Geodyn. de Chaisnes Alp., Univ. de Savoie, Savoie, France. Jakubick, A. T., and T. Franz (1993). Vacuum testing of the permeability of the excavation damaged zone, Rock Mech. Rock Engng., 26(2), 165-182. Patriarche, D., Pili, E., Adler, P. M., and J.-F. Thovert (2007). Stereological analysis of fractures in the Roselend tunnel and permeability determination, Water Resour. Res., 43, W09421. Richon, P., Perrier, F., Sabroux, J.-C., Trique, M., Ferry, C., Voisin, V., and E. Pili (2004). Spatial and time variations of radon-222 concentration in the atmosphere of a dead-end horizontal tunnel, J. Environ. Radioact., 78, 179-198. Richon, P., Perrier, F., Pili, E., and J.-C. Sabroux (2009). Detectability and significance of the 12hr barometric tide in radon-222 signal, dripwater flow rate, air temperature and carbon dioxide

  19. New Results on the Spectral Evolution of Magnetar Bright Bursts

    Science.gov (United States)

    Younes, George A.; Kouveliotou, C.; van der Horst, A.; GBM Magnetar Team

    2013-04-01

    Magnetars are isolated neutron stars characterized by long spin periods (2-12 s) and large spin down rates, implying a very strong magnetic field, B>10E14 G. Magnetars exhibit short bursts of hard X-/soft gamma-rays with luminosities ranging from 10E37 to 10E41 erg/s. The magnetar SGR J1550-5418 entered an extremely active bursting episode, starting on 2008 October 03 until 2009 April 17, during which Fermi Gamma-ray Burst Monitor (GBM) observed several hundred bursts from this source. Such wealth of bursts resulted in the largest catalog of detailed temporal and spectral results for SGR J1550-5418. Here, we discuss new results from time-resolved spectral analysis of the brightest bursts from this source. Our analysis, together with the comparison of our results with other magnetar bursts, enabled us to put strong constraints on the theories underlying the magnetar bursts emission mechanism.

  20. The Five Year Fermi/GBM Magnetar Burst Catalog

    Science.gov (United States)

    Collazzi, A. C.; Kouveliotou, C.; van der Horst, A. J.; Younes, G. A.; Kaneko, Y.; Göğüş, E.; Lin, L.; Granot, J.; Finger, M. H.; Chaplin, V. L.; Huppenkothen, D.; Watts, A. L.; von Kienlin, A.; Baring, M. G.; Gruber, D.; Bhat, P. N.; Gibby, M. H.; Gehrels, N.; McEnery, J.; van der Klis, M.; Wijers, R. A. M. J.

    2015-05-01

    Since launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has detected many hundreds of bursts from magnetar sources. While the vast majority of these bursts have been attributed to several known magnetars, there is also a small sample of magnetar-like bursts of unknown origin. Here, we present the Fermi/GBM magnetar catalog, providing the results of the temporal and spectral analyses of 440 magnetar bursts with high temporal and spectral resolution. This catalog covers the first five years of GBM magnetar observations, from 2008 July to 2013 June. We provide durations, spectral parameters for various models, fluences, and peak fluxes for all the bursts, as well as a detailed temporal analysis for SGR J1550-5418 bursts. Finally, we suggest that some of the bursts of unknown origin are associated with the newly discovered magnetar 3XMM J185246.6+0033.7.

  1. The Five Year Fermi/GBM Magnetar Burst Catalog

    CERN Document Server

    Collazzi, A C; van der Horst, A J; Younes, G A; Kaneko, Y; Gogus, E; Lin, L; Granot, J; Finger, M H; Chaplin, V L; Huppenkothen, D; Watts, A L; von Kienlin, A; Baring, M G; Gruber, D; Bhat, P N; Gibby, M H; Gehrels, N; McEnery, J; van der Klis, M; Wijers, R A M J

    2015-01-01

    Since launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has detected many hundreds of bursts from magnetar sources. While the vast majority of these bursts have been attributed to several known magnetars, there is also a small sample of magnetar-like bursts of unknown origin. Here we present the Fermi/GBM magnetar catalog, giving the results of the temporal and spectral analyses of 440 magnetar bursts with high temporal and spectral resolution. This catalog covers the first five years of GBM magnetar observations, from July 2008 to June 2013. We provide durations, spectral parameters for various models, fluences and peak fluxes for all the bursts, as well as a detailed temporal analysis for SGR J1550-5418 bursts. Finally, we suggest that some of the bursts of unknown origin are associated with the newly discovered magnetar 3XMM J185246.6+0033.7.

  2. THE FIVE YEAR FERMI/GBM MAGNETAR BURST CATALOG

    Energy Technology Data Exchange (ETDEWEB)

    Collazzi, A. C. [SciTec, Inc., 100 Wall Street, Princeton, NJ 08540 (United States); Kouveliotou, C.; Horst, A. J. van der; Younes, G. A. [Department of Physics, The George Washington University, 725 21st Street NW, Washington, DC 20052 (United States); Kaneko, Y.; Göğüş, E. [Sabancı University, Orhanlı-Tuzla, İstanbul 34956 (Turkey); Lin, L. [François Arago Centre, APC, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris (France); Granot, J. [Department of Natural Sciences, The Open University of Israel, 1 University Road, P.O. Box 808, Raanana 43537 (Israel); Finger, M. H. [Universities Space Research Association, NSSTC, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Chaplin, V. L. [School of Medicine, Vanderbilt University, 1161 21st Avenue S, Nashville, TN 37232 (United States); Huppenkothen, D. [Center for Data Science, New York University, 726 Broadway, 7th Floor, New York, NY 10003 (United States); Watts, A. L. [Anton Pannekoek Institute, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Kienlin, A. von [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Gruber, D. [Planetarium Südtirol, Gummer 5, I-39053 Karneid (Italy); Bhat, P. N. [CSPAR, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Gibby, M. H., E-mail: acollazzi@scitec.com [Jacobs Technology, Inc., Huntsville, AL (United States); and others

    2015-05-15

    Since launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has detected many hundreds of bursts from magnetar sources. While the vast majority of these bursts have been attributed to several known magnetars, there is also a small sample of magnetar-like bursts of unknown origin. Here, we present the Fermi/GBM magnetar catalog, providing the results of the temporal and spectral analyses of 440 magnetar bursts with high temporal and spectral resolution. This catalog covers the first five years of GBM magnetar observations, from 2008 July to 2013 June. We provide durations, spectral parameters for various models, fluences, and peak fluxes for all the bursts, as well as a detailed temporal analysis for SGR J1550–5418 bursts. Finally, we suggest that some of the bursts of unknown origin are associated with the newly discovered magnetar 3XMM J185246.6+0033.7.

  3. SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis

    Directory of Open Access Journals (Sweden)

    Uygur Berna

    2011-11-01

    Full Text Available Abstract Background SLUG is a zinc-finger transcription factor of the Snail/Slug zinc-finger family that plays a role in migration and invasion of tumor cells. Mechanisms by which SLUG promotes migration and invasion in prostate cancers remain elusive. Methods Expression level of CXCR4 and CXCL12 was examined by Western blot, RT-PCR, and qPCR analyses. Forced expression of SLUG was mediated by retroviruses, and SLUG and CXCL12 was downregulated by shRNAs-expressing lentiviruses. Migration and invasion of prostate cancer were measured by scratch-wound assay and invasion assay, respectively. Research We demonstrated that forced expression of SLUG elevated CXCR4 and CXCL12 expression in human prostate cancer cell lines PC3, DU145, 22RV1, and LNCaP; conversely, reduced expression of SLUG by shRNA downregulated CXCR4 and CXCL12 expression at RNA and protein levels in prostate cancer cells. Furthermore, ectopic expression of SLUG increased MMP9 expression and activity in PC3, 22RV1, and DU-145 cells, and SLUG knockdown by shRNA downregulated MMP9 expression. We showed that CXCL12 is required for SLUG-mediated MMP9 expression in prostate cancer cells. Moreover, we found that migration and invasion of prostate cancer cells was increased by ectopic expression of SLUG and decreased by SLUG knockdown. Notably, knockdown of CXCL12 by shRNA impaired SLUG-mediated migration and invasion in prostate cancer cells. Lastly, our data suggest that CXCL12 and SLUG regulate migration and invasion of prostate cancer cells independent of cell growth. Conclusion We provide the first compelling evidence that upregulation of autocrine CXCL12 is a major mechanism underlying SLUG-mediated migration and invasion of prostate cancer cells. Our findings suggest that CXCL12 is a therapeutic target for prostate cancer metastasis.

  4. Modelling Morphogenesis: From Single Cells to Crawling Slugs

    NARCIS (Netherlands)

    Savill, N.J.; Hogeweg, P.

    2002-01-01

    We present a three-dimensional hybrid cellular automata (CA)/partial differential equation (PDE) model that allows for the study of morphogenesis in simple cellular systems. We apply the model to the cellular slime mold Dictyostelium discoideum "from single cells to crawling slug". Using simple loca

  5. Individual based model of slug population and spatial dynamics

    NARCIS (Netherlands)

    Choi, Y.H.; Bohan, D.A.; Potting, R.P.J.; Semenov, M.A.; Glen, D.M.

    2006-01-01

    The slug, Deroceras reticulatum, is one of the most important pests of agricultural and horticultural crops in UK and Europe. In this paper, a spatially explicit individual based model (IbM) is developed to study the dynamics of a population of D. reticulatum. The IbM establishes a virtual field wit

  6. Propylene polymerization in a circulating slugging fluidized bed reactor

    NARCIS (Netherlands)

    Putten, van Inge Cornelia

    2004-01-01

    The work presented in this thesis is concerned with research on the riser of a circulating fluidized bed system for olefin polymerization. In the riser section, fluidization takes place in the transporting slugging mode and polymer particles are produced in the riser in a non-isothermal way. Propert

  7. Simulation of horizontal pipe two-phase slug flows using the two-fluid model

    Energy Technology Data Exchange (ETDEWEB)

    Ortega Malca, Arturo J. [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Mecanica. Nucleo de Simulacao Termohidraulica de Dutos (SIMDUT); Nieckele, Angela O. [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Mecanica

    2005-07-01

    Slug flow occurs in many engineering applications, mainly in the transport of hydrocarbon fluids in pipelines. The intermittency of slug flow causes severe unsteady loading on the pipelines carrying the fluids, which gives rise to design problems. Therefore, it is important to be able to predict the onset and development of slug flow as well as slug characteristics. The present work consists in the simulation of two-phase flow in slug pattern through horizontal pipes using the two-fluid model in its transient and one-dimensional form. The advantage of this model is that the flow field is allowed to develop naturally from a given initial conditions as part of the transient calculation; the slug evolves automatically as a product of the computed flow development. Simulations are then carried out for a large number of flow conditions that lead a slug flow. (author)

  8. How Long does a Burst Burst?

    CERN Document Server

    Zhang, Bin-Bin; Murase, Kohta; Connaughton, Valerie; Briggs, Michael S

    2013-01-01

    Several gamma-ray bursts (GRBs) last much longer (~ hours) in gamma-rays than typical long GRBs (~ minutes), and recently it was proposed that these "ultra-long GRBs" may form a distinct population, probably with a different (e.g. blue supergiant) progenitor than typical GRBs. However, Swift observations have suggested that many GRBs have extended central engine activities manifested as flares and internal plateaus in X-rays. We perform a comprehensive study on a large sample of Swift GRBs with XRT observations to investigate GRB central engine activity duration and to check whether ultra-long GRBs are special. We define burst duration t_{burst} based on both gamma-ray and X-ray light curves rather than using gamma-ray observations only. We show that the distribution of t_{burst} peaks at ~ 320s for the entire sample, with 17.6% GRBs having t_{burst} > 10^3 s and 5.4% GRBs having t_{burst} > 10^4 s. The distribution shows a tail at the long t_{burst} end. The existence of a separate population is not ruled ou...

  9. Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer

    Directory of Open Access Journals (Sweden)

    Kristine von Maltzan

    2016-02-01

    Full Text Available The Slug transcription factor plays an important role in ultraviolet radiation (UVR-induced skin carcinogenesis, particularly in the epithelial-mesenchymal transition (EMT occurring during tumor progression. In the present studies, we investigated the role of Slug in two-stage chemical skin carcinogenesis. Slug and the related transcription factor Snail were expressed at high levels in skin tumors induced by 7,12-dimethylbenz[α]anthracene application followed by 12-O-tetradecanoylphorbol-13-acetate (TPA treatment. TPA-induced transient elevation of Slug and Snail proteins in normal mouse epidermis and studies in Slug transgenic mice indicated that Slug modulates TPA-induced epidermal hyperplasia and cutaneous inflammation. Although Snail family factors have been linked to inflammation via interactions with the cyclooxygenase-2 (COX-2 pathway, a pathway that also plays an important role in skin carcinogenesis, transient TPA induction of Slug and Snail appeared unrelated to COX-2 expression. In cultured human keratinocytes, TPA induced Snail mRNA expression while suppressing Slug expression, and this differential regulation was due specifically to activation of the TPA receptor. These studies show that Slug and Snail exhibit similar patterns of expression during both UVR and chemical skin carcinogenesis, that Slug and Snail can be differentially regulated under some conditions and that in vitro findings may not recapitulate in vivo results.

  10. Experimental investigation of the effect of liquid viscosity on slug flow in small diameter bubble column

    Directory of Open Access Journals (Sweden)

    Azzopardi Barry John

    2012-04-01

    Full Text Available The effect of liquid viscosity on slug flow in a 50 mm diameter bubble column was investigated experimentally using air-silicone oil as operating fluid with silicone oil of viscosities 5, 100, 1000 and 5000 mPa.s. Data was collected using Electrical Capacitance Tomography (ECT, a non-intrusive advanced instrumentation measuring technique and the high Speed Video Camera, through which the slug parameters such as length of Taylor bubbles and liquid slug, void fraction in Taylor bubbles and liquid slug, slug frequency, film thickness and pressure gradient in the slug, were measured and analyzed. The analysis was done using the void fraction time series, probability density function and power spectral density plots. Superficial gas velocities of 0.02≤Ugs≤0.361 m/s were used in the experiment. It was also observed that as viscosity increases, slug frequency, structure velocity, length of liquid slug, void fraction in liquid slug and void fraction in Taylor bubbles decreases; while the length of Taylor bubble, film thickness and pressure gradient in the slug increases.

  11. 300 Area VOC Program Slug Test Characterization Results for Selected Test/Depth Intervals for Wells 399-2-5, 399-3-22, and 399-4-14

    Energy Technology Data Exchange (ETDEWEB)

    Newcomer, Darrell R.

    2008-03-01

    Multiple, stress-level slug tests were performed at selected test/depth intervals within wells 399-2-5, 399-3-22, and 399-4-14 as part of the 300 Area volatile organic compound characterization program at the Hanford Site in Washington State. The temporary test screen lengths were characterized as the boreholes were advanced to their final drill depths and before their completion as monitor-well facilities. Following well completion, slug tests were performed in the final, completed well-screen sections. The objectives of the slug tests were to provide the vertical distribution of hydraulic conductivity with depth at these locations and to support selection of the final well screen-depth interval for each of these monitor-well facilities.

  12. 300 Area VOC Program Slug Test Characterization Results for Selected Test/Depth Intervals for Wells 399-2-5, 399-3-22, and 399-4-14

    International Nuclear Information System (INIS)

    Multiple, stress-level slug tests were performed at selected test/depth intervals within wells 399-2-5, 399-3-22, and 399-4-14 as part of the 300 Area volatile organic compound characterization program at the Hanford Site in Washington State. The temporary test screen lengths were characterized as the boreholes were advanced to their final drill depths and before their completion as monitor-well facilities. Following well completion, slug tests were performed in the final, completed well-screen sections. The objectives of the slug tests were to provide the vertical distribution of hydraulic conductivity with depth at these locations and to support selection of the final well screen-depth interval for each of these monitor-well facilities.

  13. PIV Investigations on Secondary Flow Structures in Horizontal Slug Flows

    OpenAIRE

    Aguas Fernández, Pedro José

    2011-01-01

    Liquid and gas phases circulate horizontally through the same channel in many industrial processes. They can do it following different patterns of so-called two-phase flow. Depending on the superficial velocity of each one of the phases, the flow can vary. The different types of flows observed in horizontal pipes are bubbly flow, stratified flow,wavy flow, slug flowand annular flow. The first formal classification of flow patterns was carried out by Taitel and Dukler during the...

  14. Severe slugging in gas-liquid two-phase pipe flow

    OpenAIRE

    Malekzadeh, R.

    2012-01-01

    transportation facilities. In an offshore oil and gas production facility, pipeline-riser systems are required to transport two-phase hydrocarbons from subsurface oil and gas wells to a central production platform. Severe slugs reaching several thousands pipe diameters may occur when transporting gas and liquid in these pipeline-riser systems. Severe slugging creates potential problems in the platform facilities, e.g. separators, pumps, and compressors. Severe slugging may cause flooding and ...

  15. Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia

    OpenAIRE

    Kazumi Ebine; Chow, Christina R.; DeCant, Brian T.; Hattaway, Holly Z.; Grippo, Paul J.; Krishan Kumar; Munshi, Hidayatullah G.

    2016-01-01

    Cells in the pancreas that have undergone acinar-ductal metaplasia (ADM) can transform into premalignant cells that can eventually become cancerous. Although the epithelial-mesenchymal transition regulator Snail (Snai1) can cooperate with Kras in acinar cells to enhance ADM development, the contribution of Snail-related protein Slug (Snai2) to ADM development is not known. Thus, transgenic mice expressing Slug and Kras in acinar cells were generated. Surprisingly, Slug attenuated Kras-induced...

  16. Evaluation of local tolerance of a plant extract by the slug mucosal irritation (SMI) assay

    OpenAIRE

    Veryser, Lieselotte; Lenoir, Joke; Boonen, Jente; Bracke, Nathalie; Wynendaele, Evelien; ADRIAENS, Els; Nelis, Hans; Wever, Bram De; Remon, Jean Paul; De Spiegeleer, Bart

    2015-01-01

    This article describes the performance of a laboratory exercise, the Slug Mucosal Irritation (SMI) assay, carried out by third year undergraduate students, to investigate the local tolerance of an ethanolic plant extract. The plant extract, Spilanthes acmella, contains various bio-active compounds, such as the N-alkylamide spilanthol. After administration of the plant extract to the slugs, they were observed for possible discomfort and tissue damage. When slugs are exposed to a substance with...

  17. Stability of stratified flow and slugging in horizontal gas-liquid flow

    Institute of Scientific and Technical Information of China (English)

    GU Hanyang; GUO Liejin

    2005-01-01

    A transient one-dimensional two-fluid model is proposed to investigate numerically the interfacial instability and the onset of slugging for liquid-gas flow in a horizontal duct. In the present model, the effects of surface tension and transverse variations in dynamic pressure are taken into account. The evolution of interfacial disturbances is displayed and compared with the linear viscous KelvinHelmholtz stability analyses. It shows that interfacial wave is more instable due to the non-linear effect. The model predicts well the stability limit of stratified flow in comparison with the experimental data, and also automatically tracks the onset of slugging. The results show that the initiation of hydrodynamic slugging is related to local interfacial instability. Based on the cycle of slugging, a model for slug frequency is presented, which predicts the trends of slug frequencies with gas/liquid flow rate well in comparison with the available data. The effects of physical properties on slugging have been examined. It is found that with the increase in the gas viscosity and liquid density the slugging would be inhibited, whereas, with the increase in liquid viscosity and gas density, the slugging can be promoted.

  18. Online Slug Detection in Multi-phase Transportation Pipelines Using Electrical Tomography

    DEFF Research Database (Denmark)

    Pedersen, Simon; Mai, Christian; Hansen, Leif;

    2015-01-01

    Slugging flow in offshore oil & gas multi-phase transportation pipelines cause big challenges as the flow regime induces flow and pressure oscillations in the multi-phase pipelines. The negative impacts of the most severe slugs are significant and thus the elimination of slugging flow...... in the back pressure from control valves. The biggest limitation using ERT is the lack of ability to distinguish between gas and oil, and thus the ERT can only be used as an effective slug detect measurement when the oil-to-water ratio is low....

  19. Three-dimensional numerical simulations of three-phase slug flows in horizontal pipes

    Science.gov (United States)

    Wang, Yan; Yang, Junfeng; Matar, Omar

    2015-11-01

    One of the most common flow regimes in pipelines is that of slug flow: slug bodies corresponding to alternating blocks of aerated liquid which bridge the pipe, separated by elongated bubbles; the latter ride atop a liquid layer. The slugs travel at velocities that exceed the mixture superficial velocity; this can potentially cause structural damage, particularly at pipe bends and junctions. Two-phase slug flows have received considerable attention in the literature both experimentally and computationally but there has been very little work carried out on three-phase slugging. In the present work, the evolution of oil-water-air three-phase slug flow in a horizontal cylindrical pipe is investigated using two-dimensional and three-dimensional computational fluid dynamics simulations. The parameters characterising three-phase slug flow, e.g. slug length, propagation velocity, and slug formation frequency, are determined for various gas and liquid superficial velocities for a given pipe geometry. The results of this work are compared to available experimental data and numerical solutions based on approximate, one-dimensional models relying on the use of empirical correlations. EPSRC Programme Grant, MEMPHIS, EP/K0039761/1.

  20. A Probabilistic Approach for Predicting Average Slug Frequency in Horizontal Gas/Liquid Pipe Flow

    Directory of Open Access Journals (Sweden)

    Kadri U.

    2013-02-01

    Full Text Available In this paper, we present a model for predicting the average slug frequency in horizontal gas/liquid pipe flow. The model considers the probability of slug formation if slugs are triggered at the antinodes of a sinusoidal perturbation, along the pipe at the frequency of oscillation of the interface. A slug is assumed to form if and only if triggered at a space-time far enough from existing slugs. The probability of forming slugs is found to decrease with distance from the inlet, since the downstream passage of existing slugs prevents the formation of new slugs. Predictions by the model are compared with air/water, freon/water and air/oil measurements found in literature, with a satisfactory agreement. However, a deviation from measurements is observed when considering high viscosity liquid. The model contributes to the prediction of slug flow regime and can act as a guideline toward the design of gas/liquid horizontal pipe flow.

  1. Experiments on slug impact loading of the reactor vessel head during a postulated steam explosion

    International Nuclear Information System (INIS)

    A steam explosion in a reactor pressure vessel could cause a strong molten fuel slug impact on the vessel head, whose failure would question the integrity of the reactor containment. The capacity of a typical pressurized water reactor vessel head to carry slug impacts is therefore investigated. The slug interaction with the complex upper internal structures is taken into account. This interaction increases the capacity of the head and reduces its parameter sensitivity. Rough theoretical assessments are presented in this paper. Model experiments are being prepared to obtain reliable results. The similarity conditions for slug-structure impact problems are discussed. (orig.)

  2. SDSS Pre-Burst Observations of Recent Gamma-Ray Burst Fields

    CERN Document Server

    Cool, R J; Brinkmann, J; Eisenstein, D J; Hogg, D W; Schlegel, D J; Schneider, D P; Vanden Berk, Daniel E; Berk, Daniel E. Vanden; Blanton, Michael R.; Cool, Richard J.; Eisenstein, Daniel J.; Hogg, David W.; Schlegel, David J.; Schneider, Donald P.

    2006-01-01

    In this paper, we present Sloan Digital Sky Survey (SDSS) photometry and spectroscopy in the fields of 24 gamma-ray bursts (GRBs) observed by Swift, including bursts localized by Swift, HETE-2, and INTEGRAL, after December 2004. After this bulk release, we plan to provide individual releases of similar data shortly after the localization of future bursts falling in the SDSS survey area. These data provide a solid basis for the astrometric and photometric calibration of follow-up afterglow searches and monitoring. Furthermore, the images provided with this release will allow observers to find transient objects up to a magnitude fainter than possible with Digitized Sky Survey image comparisons.

  3. The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma

    Directory of Open Access Journals (Sweden)

    Wang Xin-sheng

    2010-07-01

    Full Text Available Abstract Objectives This study explored the expression and function of Slug in human extrahepatic hilar cholangiocarcinoma (EHC to identify its role in tumor progression. Methods The expression of Snail and Slug mRNA in 52 human tissue samples of EHC was investigated. The mRNA of Snail and Slug were quantified using reverse transcriptase-PCR, and correlations with E-cadherin expression and clinicopathological factors were investigated. We then investigated transfection of Slug cDNA in endogenous E-cadherin-positive human EHC FRH0201 cells, selectively induced the loss of E-cadherin protein expression, and then small interfering RNA (siRNA for inhibition of Slug expression in endogenous Slug-positive human EHC QBC939 cells, selectively induced the loss of Slug protein expression. A Boyden chamber transwell assay was used for invasion. Results Slug mRNA was overexpressed in 18 cases (34.6% of EHC compared with adjacent noncancerous tissue. E-Cadherin protein expression determined in the same 52 cases by immunohistochemistry was significantly down-regulated in those cases with Slug mRNA overexpression (P = 0.0001. The tumor and nontumor ratio of Slug mRNA was correlated with nodal metastasis(p = 0.0102, distant metastasis (p = 0.0001and Survival time(p = 0.0443. However, Snail mRNA correlated with neither E-cadherin expression nor tumor invasiveness. By inhibiting Slug expression by RNA interference, we found that reduced Slug levels upregulated E-cadherin and decreased invasion in QBC939 cell. When the QBC939 cells was infected with Slug cDNA,, significant E-cadherin was downregulated and increased invasion in QBC939 cell. Conclusions The results suggested that Slug expression plays an important role in both the regulation of E-cadherin expression and in the acquisition of invasive potential in human EHC. Slug is possibly a potential target for an antitumor therapy blocking the functions of invasion and metastasis in human EHCs.

  4. Observations of cosmic gamma ray bursts with WATCH on EURECA

    DEFF Research Database (Denmark)

    Brandt, Søren; Lund, N.; Castro-Tirado, A. J.

    1995-01-01

    19 Cosmic Gamma-Ray Bursts were detected by the WATCH wide field X-ray monitor during the 11 months flight of EURECA. The identification of the bursts were complicated by a high frequency of background of events caused by high energy cosmic ray interactions in the detector and by low energy......, trapped particle streams. These background events may simulate the count rate increases characteristic of cosmic gamma bursts. For 12 of the detected events, their true cosmic nature have been confirmed through consistent localizations of the burst sources based on several independent WATCH data sets...

  5. Tandonia kusceri (Pulmonata: Milacidae, a slug new for Slovakia

    Directory of Open Access Journals (Sweden)

    Ondřej Korábek

    2016-07-01

    Full Text Available Tandonia kusceri (Wagner, 1931 is reported from Slovakia for the first time. The slug was found in the Ružinov and Petržalka housing estates, Bratislava, in 2014 and 2015, respectively. Our observations suggest that the species is well established in the Slovak capital. This finding calls for verification of some of the older reports of a similar species Tandonia rustica beyond the eastern border of its native range. Owing to unresolved taxonomic issues, the name T. kusceri should be applied only tentatively.

  6. Anti-Slug Control with Non-Linear State Estimation

    OpenAIRE

    Syre, Terese Vardenær

    2012-01-01

    In offshore production, the two-phase mixture of oil and gas is transported from the seabed oil wells to the surface facilities by pipelines and risers. The two-phase flow can have different flow regimes, where severe slugging is one undesirable flow regime and an effective solution is needed to prevent it. The recommended solution is active control of the top-side choke valve. Previously, controllability analysis is done of two-phase flow in a 4-state pipeline-riser model. This analyze concl...

  7. Transformation of a Water Slug in Free Fall Under the Conditions of Exposure to an Air Flow Orthogonal to the Direction of the Slug Motion

    Science.gov (United States)

    Volkov, R. S.; Zabelin, M. V.; Kuznetsov, G. V.; Strizhak, P. A.

    2016-07-01

    An experimental study has been made of the influence of an orthogonal (side) air flow propagating with a velocity to 5 m/s on the phases of transformation of a water slug with an initial volume of 0.05-0.5 liter in free fall from a height of 3 m. Use was made of Phantom V411 and Phantom Miro M310 high-speed video cameras and a Tema Automotive software system with the function of continuous tracking. The laws of retardation of the phases of transformation of the water slug from the instant of formation to that of formation of a droplet cloud under the action of the air flow orthogonal to the direction of the slug motion, and also of the deceleration, removal, and destruction of the droplets and fragments of water separating from the slug surface, have been established.

  8. Long liquid slugs in stratified gas/liquid flow in horizontal and slightly inclined pipes

    NARCIS (Netherlands)

    Kadri, U.

    2009-01-01

    Long liquid slugs reaching several hundreds pipe diameter may appear when transporting gas and liquid in horizontal and near horizontal pipes. The long slugs cause system vibration and separation difficulties that may lead to operational failures. Identifying and predicting the time and length scale

  9. Slug inhibition increases radiosensitivity of oral squamous cell carcinoma cells by upregulating PUMA.

    Science.gov (United States)

    Jiang, Fangfang; Zhou, Lijie; Wei, Changbo; Zhao, Wei; Yu, Dongsheng

    2016-08-01

    As a new strategy, radio-gene therapy was widely used for the treatment of cancer patients in recent few years. Slug was involved in the radioresistance of various cancers and has been found to have an anti-apoptotic effect. This study aims to investigate whether the modulation of Slug expression by siRNA affects oral squamous cell carcinoma sensitivity to X-ray irradiation through upregulating PUMA. Two oral squamous cell carcinoma cell lines (HSC3 and HSC6) were transfected with small interfering RNA (siRNA) targeting Slug and subjected to radiotherapy in vitro. After transfection with Slug siRNA, both HSC3 and HSC6 cells showed relatively lower expression of Slug and higher expression of PUMA. The Slug siRNA transfected cells showed decreased survival and proliferation rates, an increased apoptosis rate and enhanced radiosensitivity to X-ray irradiation. Our results revealed that Slug siRNA transfection in combination with radiation increased the expression of PUMA, which contributed to radiosensitivity of oral squamous cell carcinoma cells. Thus, controlling the expression of Slug might contribute to enhance sensitivity of HSC3 and HSC6 cells toward X-ray irradiation in vitro by upregulating PUMA. PMID:27277529

  10. Experimental investigation of terrain slugging: formation mechanism and potential mitigation methods

    NARCIS (Netherlands)

    Schiferli, W.; Hansen, J.H.; Brasjen, B.J.; Belfroid, S.P.C.

    2013-01-01

    An experimental study on terrain-induced slugging on shallow inclines (typically less than 3°) has been conducted, using three setups with a pipe diameter of around 1”, with incline lengths of 1 m, 3 m and 24 m. In addition to an extensive characterization of the formation and evolution of slugs as

  11. Severe slugging in oil-well simulations using a drift flux code

    NARCIS (Netherlands)

    Belfroid, S.P.C.; Linden, R.J.P. van der; Alberts, G.J.N.; Aasheim, R.; Schulkes, R.

    2010-01-01

    To design and evaluate slugging control strategies, a simulator that is capable to simulate severe slugging accurately with limited CPU-needs is required; therefore a drift flux simulator was developed. The drift-flux simulator was used to simulate a field case. The pressure drop was predicted very

  12. Relationships Between Aphids (Insecta: Homoptera: Aphididae) and Slugs (Gastropoda: Stylommatophora: Agriolimacidae) Pests of Legumes (Fabaceae: Lupinus).

    Science.gov (United States)

    Kozłowski, Jan; Strażyński, Przemysław; Jaskulska, Monika; Kozłowska, Maria

    2016-01-01

    Lupin plants are frequently damaged by various herbivorous invertebrates. Significant among these are slugs and aphids, which sometimes attack the same plants. Relationships between aphids, slugs and food plant are very interesting. Grazing by these pests on young plants can lead to significant yield losses. There is evidence that the alkaloids present in some lupin plants may reduce grazing by slugs, aphids and other invertebrates. In laboratory study was analyzed the relationships between aphid Aphis craccivora and slug Deroceras reticulatum pests of legumes Lupinus angustifolius. It was found that the presence of aphids significantly reduced slug grazing on the plants. The lupin cultivars with high alkaloid content were found to be less heavily damaged by D. reticulatum, and the development of A. craccivora was found to be inhibited on such plants. PMID:27324580

  13. Fabrication of rare-earth bearing fuel slug by injection casting method

    International Nuclear Information System (INIS)

    Herein, U.10wt%Zr fuel slugs containing 0, 3, and 7 wt%RE were prepared by an injection casting method and their characteristics were evaluated. The as-cast fuel slugs were generally sound and fabricated to the full length of the mold. However, the increased amount of the charged RE noticeably deteriorated the quality of the casting components such as melting crucible. Chemical analysis of the U.10Zr and U.10Zr.3RE slugs showed that the target composition was matched to within 1.0 wt%. In contrast, the composition of the U.10Zr.7RE fuel slug differed by as much as 4.6 wt% from the target. Therefore, more protective casting variables should be considered, when casting high RE-bearing fuel slugs. KAERI seeks to develop and demonstrate the technologies needed to transmute the long-lived transuranic actinide isotopes in spent nuclear fuel into shorter-lived fission products

  14. Recreating Riser Slugging Flow Based on an Economic Lab-sized Setup

    DEFF Research Database (Denmark)

    Hansen, Lasse; Pedersen, Simon; Yang, Zhenyu;

    2013-01-01

    As a kind of periodic phenomenon, the slugging flow in the offshore oil & gas production addresses a lot of attentions, due to its limitation of production rate, periodic overload processing facilities, and even direct cause of emergent shutdown. This work studies the emulation of the riser...... slugging flow in the offshore oil & gas production, by constructing an economical lab-sized setup in the university campus. Firstly, the construction and used components for the lab setup are illustrated; then, the constructed setup is validated by checking the consistency with some existing typical riser...... slug model, besides extensive experimental tests. The theoretical analysis and experimental results show that this simple setup can recreate the key features of slugging flow phenomenon reasonably precise, and it serves as a good platform for further slug control study....

  15. An Experimental Study of the Flowrate Transients in Slug Flow

    Institute of Scientific and Technical Information of China (English)

    HELimin; CHENZhenyu; 等

    2002-01-01

    An investigation of the characteristics of flowrate transients within slug flow was conducted in a largescale outdoor testing facility.The test section consisted of a 378m long,7.62cm diameter stainless steel pipe. Air and water were used as the test fluids.The response to a change of flowrate o either phase or two phases was measured using a series of pressure transducers and differential pressure transducers.An increase or decrease in gas flowrate caused a pressure overshoot above the value at new steady state or led to a pressure undershoot to form a temporary stratified flow.Pressure waves existed in the pipeline,spreading from the entrance to the exit.The magnitude of pressure overshoot in “up-gas”transient or of pressure undershoot and period of the temporary stratified flow in “Down-gas” transient are related to the change of gas flowrate and the distance away from the entrance.In contrast,the change in liquid flowrate was accommodated by smooth transitions between the corresponding steady states,and only one obvious change was found in the slug frequency.According to experimental results,the pressure overshoot,pressure undershoot and the pressure wave propagation were analyzed,and the phenomena were explained reasonably.Some correlations for the calculation of the pressure overshoot and undershoot were proposed.

  16. Laboratory Tests for Group and Individual Exposures of Arion lusitanicus Mabille Slugs to Different Molluscicide Baits

    Directory of Open Access Journals (Sweden)

    Bojan Stojnić

    2008-01-01

    Full Text Available Molluscicide baits based on different active ingredients were tested in a seven-day laboratory trial on juveniles and young adults of Arion lusitanicus Mabille slug collected in ruderal sites during June and July of 2008. Before setting the trial, the slugs were adapted to laboratory conditions. The testing was conducted using a modified version of the method proposed by Godan (1983 and Wiktor (1989. The slugs were kept in arenas under controlled conditions (20-24oC temperature, 80-90% relative air humidity, no air stream, diffuse daylight. Smaller(15.5 x 15.5 x 7 cm and larger (28 x 17.5 x 7 cm arenas were used, depending on slug numbers, and different rates of food and bait were administered. Plastic boxes with perforated coverage, lined with multi-ply paper moistened on a daily basis, were used as arenas. The slugs were fed on fresh salad daily, while baits were administered in open 35 mm petri dishes once for the duration of experiment. The first trial involved single-slug exposures to bait in 20 arenas per each of four treatments with two replicates and a total of 160 slugs. The second trial, group exposure, involved four treatments of five slugs per arena in six replicates with a total of 120 slugs. The products Arion and Pužomor demonstrated the highest efficacy (77.5% in the single-slug trial. The average efficacy of the product Carakol after seven days of exposure was 60.0%. Regarding group exposure, Pužomor pellets achieved 79.3% efficacy after three days and this efficacy rate remained for the rest of the experiment. On the seventh day ofexposure, Arion and Carakol had 33.3% and 40.0% efficacy, respectively.

  17. Influence of the initial conditions for the numerical simulation of two-phase slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Pachas Napa, Alex A.; Morales, Rigoberto E.M.; Medina, Cesar D. Perea

    2010-07-01

    Multiphase flows in pipelines commonly show several patterns depending on the flow rate, geometry and physical properties of the phases. In oil production, the slug flow pattern is the most common among the others. This flow pattern is characterized by an intermittent succession in space and time of an aerated liquid slug and an elongated gas bubble with a liquid film. Slug flow is studied through the slug tracking model described as one-dimensional and Lagrangian frame referenced. In the model, the mass and the momentum balance equations are applied in control volumes constituted by the gas bubble and the liquid slug. Initial conditions must be determined, which need to reproduce the intermittence of the flow pattern. These initial conditions are given by a sequence of flow properties for each unit cell. Properties of the unit cell in initial conditions should reflect the intermittence, for which they can be analyzed in statistical terms. Therefore, statistical distributions should be obtained for the slug flow variables. Distributions are complemented with the mass balance and the bubble design model. The objective of the present work is to obtain initial conditions for the slug tracking model that reproduce a better adjustment of the fluctuating properties for different pipe inclinations (horizontal, vertical or inclined). The numerical results are compared with experimental data obtained by PFG/FEM/UNICAMP for air-water flow at 0 deg, 45 deg and 90 deg and good agreement is observed. (author)

  18. Experimental characterization of solid particle transport by slug flow using Particle Image Velocimetry

    Science.gov (United States)

    Goharzadeh, A.; Rodgers, P.

    2009-02-01

    This paper presents an experimental study of gas-liquid slug flow on solid particle transport inside a horizontal pipe with two types of experiments conducted. The influence of slug length on solid particle transportation is characterized using high speed photography. Using combined Particle Image Velocimetry (PIV) with Refractive Index Matching (RIM) and fluorescent tracers (two-phase oil-air loop) the velocity distribution inside the slug body is measured. Combining these experimental analyses, an insight is provided into the physical mechanism of solid particle transportation due to slug flow. It was observed that the slug body significantly influences solid particle mobility. The physical mechanism of solid particle transportation was found to be discontinuous. The inactive region (in terms of solid particle transport) upstream of the slug nose was quantified as a function of gas-liquid composition and solid particle size. Measured velocity distributions showed a significant drop in velocity magnitude immediately upstream of the slug nose and therefore the critical velocity for solid particle lifting is reached further upstream.

  19. A Hydrodynamic Model for Slug Frequency in Horizontal Gas-Liquid Two-Phase Flow

    Institute of Scientific and Technical Information of China (English)

    刘磊; 孙贺东; 胡志华; 周芳德

    2003-01-01

    The prediction of slug frequency has important significance on gas-liquid two-phase flow. A hydrodynamic model was put forward to evaluate slug frequency for horizontal two-phase flow, based on the dependence of slug frequency on the frequency of unstable interfacial wave. Using air and water, experimental verification of the model was carried out in a large range of flow parameters. Six electrical probes were installed at different positions of a horizontal plexiglass pipe to detect slug frequency development. The pipe is 30 m long and its inner diameter is 24 ram. It is observed experimentally that the interracial wave frequency at the inlet is about i to 3 times the frequency of stable slug. The slug frequencies predicted by the model fit well with Tronconi (1990) model and the experimental data. The combination of the hydrodynamic model and the experimental data results in a conclusion that the frequency of equilibrium liquid slug is approximately half the minimum frequency of interfacial wave.

  20. Snails and slugs damaging the cut foliage, Cordyline fruticosa and use of biorationals towards their management.

    Science.gov (United States)

    Karthiga, S; Jegathambigai, V; Karunarathne, M D S D; Svinningen, A; Mikunthan, G

    2012-01-01

    Snails and slugs became a serious molluscan pests and damaging leaves of purple compacta, Cordyline fruticosa extensively grown for export at Green Farm Ltd, Sri Lanka. The export quality of leaves of C. fruticosa is lowered due to feeding of snails, Achantina fulica (Bowditch), Opeas pyrgula Schmacker and Boettgerx and Helix aspersa Muller and slugs incurring great loss to cut foliage industry. Paucity of information is available to understand snails and slugs damage and their host range that limits to develop suitable management practices. Therefore this study was aimed to determine damage, alternate hosts and to develop possible management practices. Snails and slugs damaged mainly fresh leaves of C. fruticosa. The severity of damage was 44.5% in infested field based on the visual rating method. Leaves of cassava, sting bean, okra, cucumber, passion fruit, papaya, Glyricidia and shoe flower were identified as alternate hosts and neem, Ixora and Dracaena spp were not served as alternate hosts. Among the plant materials tested for their repellence against snails and slugs revealed that neem seed powder was an irritant; neem leaves, mint leaves and Lantana leaves were acted as anti-feedant and Salt as chemical repellent. Among the barrier and bait experiments Bordeaux mixture exhibited a significant barrier effect against horizontal movement of snails. Baits made out of Metaldehyde bait, vegetables bait and jaggery had a strong effect in repelling the snails and slugs. Mulching with Madhuca longifolia punnac was the best to reduce the snails and slugs population compared to M. longifolia seed kernel powder. Oil from M. longifolia failed to reduce their population. Hence the results revealed that saponin containing M. longifolia punnac helped to eliminate snails and slugs when used as mulch. Metaldehyde, vegetable and jaggery baits are also useful to minimize their colonization further. Hence combination of these methods will help to prevent snails and slugs from

  1. Snails and slugs damaging the cut foliage, Cordyline fruticosa and use of biorationals towards their management.

    Science.gov (United States)

    Karthiga, S; Jegathambigai, V; Karunarathne, M D S D; Svinningen, A; Mikunthan, G

    2012-01-01

    Snails and slugs became a serious molluscan pests and damaging leaves of purple compacta, Cordyline fruticosa extensively grown for export at Green Farm Ltd, Sri Lanka. The export quality of leaves of C. fruticosa is lowered due to feeding of snails, Achantina fulica (Bowditch), Opeas pyrgula Schmacker and Boettgerx and Helix aspersa Muller and slugs incurring great loss to cut foliage industry. Paucity of information is available to understand snails and slugs damage and their host range that limits to develop suitable management practices. Therefore this study was aimed to determine damage, alternate hosts and to develop possible management practices. Snails and slugs damaged mainly fresh leaves of C. fruticosa. The severity of damage was 44.5% in infested field based on the visual rating method. Leaves of cassava, sting bean, okra, cucumber, passion fruit, papaya, Glyricidia and shoe flower were identified as alternate hosts and neem, Ixora and Dracaena spp were not served as alternate hosts. Among the plant materials tested for their repellence against snails and slugs revealed that neem seed powder was an irritant; neem leaves, mint leaves and Lantana leaves were acted as anti-feedant and Salt as chemical repellent. Among the barrier and bait experiments Bordeaux mixture exhibited a significant barrier effect against horizontal movement of snails. Baits made out of Metaldehyde bait, vegetables bait and jaggery had a strong effect in repelling the snails and slugs. Mulching with Madhuca longifolia punnac was the best to reduce the snails and slugs population compared to M. longifolia seed kernel powder. Oil from M. longifolia failed to reduce their population. Hence the results revealed that saponin containing M. longifolia punnac helped to eliminate snails and slugs when used as mulch. Metaldehyde, vegetable and jaggery baits are also useful to minimize their colonization further. Hence combination of these methods will help to prevent snails and slugs from

  2. Laboratory tests for group and individual exposures of Arion lusitanicus Mabille slugs to different molluscicide baits

    OpenAIRE

    Bojan Stojnić; Marina Vukša; Goran Jokić

    2008-01-01

    Molluscicide baits based on different active ingredients were tested in a seven-day laboratory trial on juveniles and young adults of Arion lusitanicus Mabille slug collected in ruderal sites during June and July of 2008. Before setting the trial, the slugs were adapted to laboratory conditions. The testing was conducted using a modified version of the method proposed by Godan (1983) and Wiktor (1989). The slugs were kept in arenas under controlled conditions (20-24oC temperature, 80-90% rela...

  3. Review of Slug Detection, Modeling and Control Techniques for Offshore Oil & Gas Production Processes

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2015-01-01

    of these methods can simultaneously reduce the oil & gas production, which is a very big concern as the production rate is the key evaluation parameter for offshore production. We conclude that the slugging flow is a well-defined phenomenon, even though this subject has been extensively investigated in the past......The current offshore oil & gas multi-phase production and transportation installations have big challenges related with the slugging flow: An unstable multi-phase flow regime where the flow rates, pressures and temperatures oscillate in the considered processes. Slug can be caused by different...

  4. Cold tolerance and freeze-induced glucose accumulation in three terrestrial slugs

    DEFF Research Database (Denmark)

    Slotsbo, Stine; Hansen, Lars Monrad; Jordaens, Kurt;

    2012-01-01

    Cold tolerance and metabolic responses to freezing of three slug species common in Scandinavia (Arion ater, Arion rufus and Arion lusitanicus) are reported. Autumn collected slugs were cold acclimated in the laboratory and subjected to freezing conditions simulating likely winter temperatures in....... Glucose increased from about 6 to 22 µg/mg dry tissue upon freezing in A. rufus, but less so in A. ater and A. lusitanicus. Glucose may thus act as a cryoprotectant in these slugs, although the concentrations are not as high as reported for other freeze tolerant invertebrates....

  5. Interplanetary Type IV Bursts

    CERN Document Server

    Hillaris, Alexander; Nindos, Alexander

    2016-01-01

    In this work we study the characteristics of moving type IV radio bursts which extend to the hectometric wavelengths (interplanetary type IV or type IV IP bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprised 48 Interplanetary type IV bursts observed by the Wind/WAVES in the 13.825 MHz?20 KHz frequency range. The dynamic spec tra of the RSTN, DAM, ARTEMIS-IV, CULGOORA, Hiraiso and IZMIRAN Radio-spectrographs were used to track the evolution of the events in the low corona; these were supplemented with SXR ?ux recordings from GOES and CME data from LASCO. Positional information for the coronal bursts were obtained by the Nan\\c{c}ay radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs and SXR ?ares. The majority of the events (45) were characterized as compact; their duration was on average 106 min. This type of events were, mostly, associated with M and X class ?ares (40 out of 45) and fast CMEs; 32 of these events had CME...

  6. Interplanetary Type IV Bursts

    Science.gov (United States)

    Hillaris, A.; Bouratzis, C.; Nindos, A.

    2016-08-01

    We study the characteristics of moving type IV radio bursts that extend to hectometric wavelengths (interplanetary type IV or type {IV}_{{IP}} bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprises 48 interplanetary type IV bursts observed with the Radio and Plasma Wave Investigation (WAVES) instrument onboard Wind in the 13.825 MHz - 20 kHz frequency range. The dynamic spectra of the Radio Solar Telescope Network (RSTN), the Nançay Decametric Array (DAM), the Appareil de Routine pour le Traitement et l' Enregistrement Magnetique de l' Information Spectral (ARTEMIS-IV), the Culgoora, Hiraso, and the Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation (IZMIRAN) Radio Spectrographs were used to track the evolution of the events in the low corona. These were supplemented with soft X-ray (SXR) flux-measurements from the Geostationary Operational Environmental Satellite (GOES) and coronal mass ejections (CME) data from the Large Angle and Spectroscopic Coronagraph (LASCO) onboard the Solar and Heliospheric Observatory (SOHO). Positional information of the coronal bursts was obtained by the Nançay Radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs, and SXR flares. The majority of the events (45) were characterized as compact, their duration was on average 106 minutes. This type of events was, mostly, associated with M- and X-class flares (40 out of 45) and fast CMEs, 32 of these events had CMEs faster than 1000 km s^{-1}. Furthermore, in 43 compact events the CME was possibly subjected to reduced aerodynamic drag as it was propagating in the wake of a previous CME. A minority (three) of long-lived type {IV}_{{IP}} bursts was detected, with durations from 960 minutes to 115 hours. These events are referred to as extended or long duration and appear to replenish their energetic electron content, possibly from electrons escaping from the corresponding coronal

  7. Experimental Study of Stable Surfaces for Anti-Slug Control in Multi-phase Flow

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Stampe, Kasper;

    2016-01-01

    Severe slugging flow is always challenging in oil & gas production, especially for the current offshore based production. The slugging flow can cause a lot of problems, such as those relevant to production safety, fatigue as well as capability. As one typical phenomenon in multi-phase flow dynamics......, the slug can be avoided or eliminated by proper facility design or control of operational conditions. Based on a testing facility which can emulate a pipeline-riser or a gas-lifted production well in a scaled-down manner, this paper experimentally studies the correlations of key operational parameters...... with severe slugging flows. These correlations are reflected through an obtained stable surface in the parameter space, which is a natural extension of the bifurcation plot. The maximal production opportunity without compromising the stability is also studied. Relevant studies have already showed...

  8. Experimental Study of Stable Surfaces for Anti-Slug Control in Multi-phase Flow

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2014-01-01

    -phase flow dynamics, the slug can be avoided or eliminated by proper facility design and control of operational conditions. Based on a testing facility which can emulate a pipeline-riser or a gas-lifted production well in a scaled-down manner, this paper experimentally studies the correlations of key......The severe slugging flow is always challenging in oil & gas production, especially for the current offshore based production. The slugging flow can cause a lot of potential problems, such as those relevant to production safety, fatigue as well as capability. As one typical phenomenon in multi...... operational parameters with severe slugging flows. These correlations are reflected through an obtained stable surface in the parameter space, which is a natural extension of the bifurcation plot. The maximal production opportunity without compromising the stability is also studied. Relevant studies have...

  9. A Repeating Fast Radio Burst

    CERN Document Server

    Spitler, L G; Hessels, J W T; Bogdanov, S; Brazier, A; Camilo, F; Chatterjee, S; Cordes, J M; Crawford, F; Deneva, J; Ferdman, R D; Freire, P C C; Kaspi, V M; Lazarus, P; Lynch, R; Madsen, E C; McLaughlin, M A; Patel, C; Ransom, S M; Seymour, A; Stairs, I H; Stappers, B W; van Leeuwen, J; Zhu, W W

    2016-01-01

    Fast Radio Bursts are millisecond-duration astronomical radio pulses of unknown physical origin that appear to come from extragalactic distances. Previous follow-up observations have failed to find additional bursts at the same dispersion measures (i.e. integrated column density of free electrons between source and telescope) and sky position as the original detections. The apparent non-repeating nature of the fast radio bursts has led several authors to hypothesise that they originate in cataclysmic astrophysical events. Here we report the detection of ten additional bursts from the direction of FRB121102, using the 305-m Arecibo telescope. These new bursts have dispersion measures and sky positions consistent with the original burst. This unambiguously identifies FRB121102 as repeating and demonstrates that its source survives the energetic events that cause the bursts. Additionally, the bursts from FRB121102 show a wide range of spectral shapes that appear to be predominantly intrinsic to the source and wh...

  10. Photoprotection in sequestered plastids of sea slugs and respective algal sources

    OpenAIRE

    Cruz, Sónia; Cartaxana, Paulo; Newcomer, Rebecca; Dionísio, Gisela; Calado, Ricardo; Serôdio, João; Pelletreau, Karen N.; Rumpho, Mary E.

    2015-01-01

    Some sea slugs are capable of retaining functional sequestered chloroplasts (kleptoplasts) for variable periods of time. The mechanisms supporting the maintenance of these organelles in animal hosts are still largely unknown. Non-photochemical quenching (NPQ) and the occurrence of a xanthophyll cycle were investigated in the sea slugs Elysia viridis and E. chlorotica using chlorophyll fluorescence measurements and pigment analysis. The photoprotective capacity of kleptoplasts was compared to ...

  11. Distribution of void fraction for gas-liquid slug flow in an inclined pipe

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In order to investigate the effect of inclination angle on the spatial distribution of phases, experiments on gas-liquid two-phase slug flow in an inclined pipe were carried out by using the optical probe and an EKTAPRO 1000 high speed motion analyzer. It has been demonstrated that the inclination angle and the mixture velocity are important parameters to influence the distribution of void fraction for upward slug flow in the inclined pipe. At high mixture velocity, the gas phase profile is axial symmetry in the cross-section of the pipe. This is similar to that for vertical slug flow. In contrast, most of the gas phase is located near the upper pipe wall at low mixture velocity. By measuring the axial variation of void fraction along the liquid slug, it can be concluded that there is a high void fraction wake region with length of 3~4D in the front of liquid slug. In the fully developed zone of liquid slug, the peak value of the void fraction is near the upper wall.

  12. Polymorphisms of the maternal Slug gene in fetal neural tube defects in a Chinese population

    Institute of Scientific and Technical Information of China (English)

    Li Guo; Hong Zhao; Yuheng Pei; Quanren He; Wan-I Li; Ting Zhang; Xiaoying Zheng; Ran Zhou; Jun Xie

    2010-01-01

    Several studies have demonstrated that Slug,which encodes a zinc finger of the Snail family of transcription factors,is a potential risk factor for neural tube defects.Neural tube defects tend to occur with a high rate in Shanxi province,China.The present case-control study investigated genotypic distributions and allele frequencies of Slug C1548A polymorphisms in DNA samples from59 women with a history of neural tube defect pregnancies and 73 controls during the same period from Shanxi Province,China.Results demonstrated that women with a history of neural tube defect pregnancies had significantly greater genotypic distributions of Slug AA genotypes and A allele frequencies compared with controls,and A allele Slug C1548A was a risk factor for neural tube defects(odds ratio = 3.444;95% confidence interval;2.021-5.868,P < 0.05).Three-dimensional structure prediction revealed that Slug C1548A resulted in transition of aspartic acid into glutamate at position 119.This indicated that these mutations could lead to damaged protein structure and function.These findings suggest that Slug C1548A gene polymorphism is closely related to neural tube defects in a population of Han Chinese origin from Shanxi Province,China

  13. Thermal Capacitance (Slug) Calorimeter Theory Including Heat Losses and Other Decaying Processes

    Science.gov (United States)

    Hightower, T. Mark; Olivares, Ricardo A.; Philippidis, Daniel

    2008-01-01

    A mathematical model, termed the Slug Loss Model, has been developed for describing thermal capacitance (slug) calorimeter behavior when heat losses and other decaying processes are not negligible. This model results in the temperature time slope taking the mathematical form of exponential decay. When data is found to fit well to this model, it allows a heat flux value to be calculated that corrects for the losses and may be a better estimate of the cold wall fully catalytic heat flux, as is desired in arc jet testing. The model was applied to the data from a copper slug calorimeter inserted during a particularly severe high heating rate arc jet run to illustrate its use. The Slug Loss Model gave a cold wall heat flux 15% higher than the value of 2,250 W/sq cm obtained from the conventional approach to processing the data (where no correction is made for losses). For comparison, a Finite Element Analysis (FEA) model was created and applied to the same data, where conduction heat losses from the slug were simulated. The heat flux determined by the FEA model was found to be in close agreement with the heat flux determined by the Slug Loss Model.

  14. The Etiology and Outcome Analysis of Neonatal Burst Suppression EEG

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lian; ZHOU Yanxia; XU Sanqing

    2007-01-01

    The neonatal burst suppression is a severe EEG pattern and always demonstrates serious damage of nerve system. But the outcome of these patients depends on the different etiology. A total of 256 cases of video EEG recordings were analyzed in order to summarize the etiology and outcome of burst suppression. The results showed that some patients in all 17 cases of burst suppression showed EEG improvement. The etiology was the dominant factor in long term outcome. It was sug-gested that effective video EEG monitoring is helpful for etiologic study and prognosis evaluation.

  15. Investigation of Non-Linear Dynamics of the Rock Massive,Using Seismological Catalogue data and Induction Electromagnetic Monitoring Data in a Rock Burst Mine.

    Science.gov (United States)

    Hachay, O. A.; Khachay, O. Y.; Klimko, V. K.; Shipeev, O. V.

    2012-04-01

    Geological medium is an open dynamical system, which is influenced on different scales by natural and man-made impacts, which change the medium state and lead as a result to a complicated many ranked hierarchic evolution. That is the subject of geo synergetics. Paradigm of physical mesomechanics, which was advanced by academician Panin V.E. and his scientific school, which includes the synergetic approach is a constructive method for research and changing the state of heterogenic materials [1]. That result had been obtained on specimens of different materials. In our results of research of no stationary geological medium in a frame of natural experiments in real rock massifs, which are under high man-made influence it was shown, that the state dynamics can be revealed with use synergetics in hierarchic medium. Active and passive geophysical monitoring plays a very important role for research of the state of dynamical geological systems. It can be achieved by use electromagnetic and seismic fields. Our experience of that research showed the changing of the system state reveals on the space scales and times in the parameters, which are linked with the peculiarities of the medium of the second or higher ranks [2-5]. Results of seismological and electromagnetic information showed the mutual additional information on different space-time levels of rock massive state, which are energetic influenced by explosions, used in mining technology. It is revealed a change of nonlinearity degree in time of the massive state by active influence on it. The description of massive movement in a frame of linear dynamical system does not satisfy the practical situation. The received results are of great significance because for the first time we could find the coincidences with the mathematical theory of open systems and experimental natural results with very complicated structure. On that base we developed a new processing method for the seismological information which can be used in

  16. A simple model for two-phase slug flow induced damping

    International Nuclear Information System (INIS)

    The two-phase flows are prevalent in various industrial fields such as nuclear engineering, chemical engineering and the petroleum industry. At high speeds, flows through piping may generate significant excitation forces, particularly at joints and bends in piping systems. Interestingly, the flows may also generate significant damping forces which can be desirable from a vibration damping point of view. The question of exactly how internal two-phase flows generate damping remains largely unanswered. Indeed so is the question for external two-phase flows, which are even more complex. The problem addressed in this study is related to the behavior of tubular structures subjected to internal two-phase slug flow or nearly slug flow. The observation of slug flow subjected to transverse vibration led to consideration of the effects of sloshing liquid slugs due to the external vibration. Indeed, in flow visualization tests, the upper free surface of the slugs in vertical flow was found to deform significantly as the tube vibrated. This suggested a possible mechanism for energy transfer from the structure to the fluid which could be (at least partially) responsible for the observed two-phase flow-induced damping. An analytical model is developed aimed at incorporating the most basic sloshing effects of liquid slugs travelling through a tube at low speed. The first part of the work demonstrates that considering slugs as as simple points masses travelling through the tube leads only to low energy transfer from the tube to the flow and thus cannot explain the level of energy transfer observed in experimental damping tests. In the second part of the work, the flow dynamics within the slug are modeled to account for linear order free surface oscillations related to first mode sloshing. Numerical solution of the resulting equations shows that the energy transfer is much higher and results in damping levels of the same order as found in experimental measurements. The results

  17. Photocontrol of fluid slugs in liquid crystal polymer microactuators

    Science.gov (United States)

    Lv, Jiu-An; Liu, Yuyun; Wei, Jia; Chen, Erqiang; Qin, Lang; Yu, Yanlei

    2016-09-01

    The manipulation of small amounts of liquids has applications ranging from biomedical devices to liquid transfer. Direct light-driven manipulation of liquids, especially when triggered by light-induced capillary forces, is of particular interest because light can provide contactless spatial and temporal control. However, existing light-driven technologies suffer from an inherent limitation in that liquid motion is strongly resisted by the effect of contact-line pinning. Here we report a strategy to manipulate fluid slugs by photo-induced asymmetric deformation of tubular microactuators, which induces capillary forces for liquid propulsion. Microactuators with various shapes (straight, ‘Y’-shaped, serpentine and helical) are fabricated from a mechanically robust linear liquid crystal polymer. These microactuators are able to exert photocontrol of a wide diversity of liquids over a long distance with controllable velocity and direction, and hence to mix multiphase liquids, to combine liquids and even to make liquids run uphill. We anticipate that this photodeformable microactuator will find use in micro-reactors, in laboratory-on-a-chip settings and in micro-optomechanical systems.

  18. Stability Analysis of Reactive Multiphase Slug Flows in Microchannels

    Directory of Open Access Journals (Sweden)

    Alejandro A. Munera Parra

    2014-05-01

    Full Text Available Conducting multiphase reactions in micro-reactors is a promising strategy for intensifying chemical and biochemical processes. A major unresolved challenge is to exploit the considerable benefits offered by micro-scale operation for industrial scale throughputs by numbering-up whilst retaining the underlying advantageous flow characteristics of the single channel system in multiple parallel channels. Fabrication and installation tolerances in the individual micro-channels result in different pressure losses and, thus, a fluid maldistribution. In this work, an additional source of maldistribution, namely the flow multiplicities, which can arise in a multiphase reactive or extractive flow in otherwise identical micro-channels, was investigated. A detailed experimental and theoretical analysis of the flow stability with and without reaction for both gas-liquid and liquid-liquid slug flow has been developed. The model has been validated using the extraction of acetic acid from n-heptane with the ionic liquid 1-Ethyl-3-methylimidazolium ethyl sulfate. The results clearly demonstrate that the coupling between flow structure, the extent of reaction/extraction and pressure drop can result in multiple operating states, thus, necessitating an active measurement and control concept to ensure uniform behavior and optimal performance.

  19. Photocontrol of fluid slugs in liquid crystal polymer microactuators.

    Science.gov (United States)

    Lv, Jiu-An; Liu, Yuyun; Wei, Jia; Chen, Erqiang; Qin, Lang; Yu, Yanlei

    2016-01-01

    The manipulation of small amounts of liquids has applications ranging from biomedical devices to liquid transfer. Direct light-driven manipulation of liquids, especially when triggered by light-induced capillary forces, is of particular interest because light can provide contactless spatial and temporal control. However, existing light-driven technologies suffer from an inherent limitation in that liquid motion is strongly resisted by the effect of contact-line pinning. Here we report a strategy to manipulate fluid slugs by photo-induced asymmetric deformation of tubular microactuators, which induces capillary forces for liquid propulsion. Microactuators with various shapes (straight, 'Y'-shaped, serpentine and helical) are fabricated from a mechanically robust linear liquid crystal polymer. These microactuators are able to exert photocontrol of a wide diversity of liquids over a long distance with controllable velocity and direction, and hence to mix multiphase liquids, to combine liquids and even to make liquids run uphill. We anticipate that this photodeformable microactuator will find use in micro-reactors, in laboratory-on-a-chip settings and in micro-optomechanical systems. PMID:27604946

  20. A repeating fast radio burst

    Science.gov (United States)

    Spitler, L. G.; Scholz, P.; Hessels, J. W. T.; Bogdanov, S.; Brazier, A.; Camilo, F.; Chatterjee, S.; Cordes, J. M.; Crawford, F.; Deneva, J.; Ferdman, R. D.; Freire, P. C. C.; Kaspi, V. M.; Lazarus, P.; Lynch, R.; Madsen, E. C.; McLaughlin, M. A.; Patel, C.; Ransom, S. M.; Seymour, A.; Stairs, I. H.; Stappers, B. W.; van Leeuwen, J.; Zhu, W. W.

    2016-03-01

    Fast radio bursts are millisecond-duration astronomical radio pulses of unknown physical origin that appear to come from extragalactic distances. Previous follow-up observations have failed to find additional bursts at the same dispersion measure (that is, the integrated column density of free electrons between source and telescope) and sky position as the original detections. The apparent non-repeating nature of these bursts has led to the suggestion that they originate in cataclysmic events. Here we report observations of ten additional bursts from the direction of the fast radio burst FRB 121102. These bursts have dispersion measures and sky positions consistent with the original burst. This unambiguously identifies FRB 121102 as repeating and demonstrates that its source survives the energetic events that cause the bursts. Additionally, the bursts from FRB 121102 show a wide range of spectral shapes that appear to be predominantly intrinsic to the source and which vary on timescales of minutes or less. Although there may be multiple physical origins for the population of fast radio bursts, these repeat bursts with high dispersion measure and variable spectra specifically seen from the direction of FRB 121102 support an origin in a young, highly magnetized, extragalactic neutron star.

  1. Oscillatory Motion of a Bi-Phasic Slug in a Teflon Reactor

    Science.gov (United States)

    Abolhasani, Milad; Jensen, Klavs

    2015-11-01

    Bi-phasic physical/chemical processes require transfer of solute/reagent molecules across the interface. Continuous multi-phase flow approaches (using gas as the continuous phase), usually fail in providing sufficient interfacial area for transfer of molecules between the aqueous and organic phases. In continuous segmented flow platforms (with a fluorinated polymer-based reactor), the higher surface tension of the aqueous phase compared to the organic phase of a bi-phasic slug, in combination with the low surface energy of the reactor wall result in a more facile motion of the aqueous phase. Thus, upon applying a pressure gradient across the bi-phasic slug, the aqueous phase of the slug moves through the organic phase and leads the bi-phasic slug, thereby limiting the available interfacial area for the bi-phasic mass transfer only to the semi-spherical interface between the two phases. Disrupting the quasi-equilibrium state of the bi-phasic slug through reversing the pressure gradient across the bi-phasic slug causes the aqueous phase to move back through the organic phase. In this work, we experimentally investigate the dynamics of periodic alteration of the pressure gradient across a bi-phasic slug, and characterize the resulting enhanced interfacial area on the bi-phasic mass transfer rate. We demonstrate the enhanced mass transfer rate of the oscillatory flow strategy compared to the continuous multi-phase approach using bi-phasic Pd catalyzed carbon-carbon and carbon-nitrogen cross coupling reactions. NSERC Postdoctoral Fellowship, Novartis Center for Continuous Manufacturing.

  2. Experimental studies of the pressures generated by a liquid oxygen slug in a magnetic field

    Science.gov (United States)

    Boulware, Jeffrey C.; Ban, Heng; Jensen, Scott; Wassom, Steve

    2010-07-01

    The strong paramagnetic susceptibility of liquid oxygen (LOX) has established it as a good candidate for a cryogenic magnetic fluid system. While its properties have been known for several decades, a fundamental understanding of the behavior of LOX in a magnetically controlled fluid system is needed for the development of a suitable space application that can operate reliably and efficiently. This study conducted quantitative experiments on the dynamics of a LOX slug in a tube when subjected to electrically-induced magnetic fields within a solenoid. The experiments used a quartz tube with an inner diameter of 1.9 mm and LOX slugs of 0.6, 1.3, 1.9, 2.5, and 3.2 mm length at various initial positions relative to the solenoid. The pressures generated by the motion of the LOX slug under the magnetic force were recorded to characterize the pressure differential generated and the breakdown of the slug. The highest attainable pressure differential was found to be 1.45 kPa, which correlated well to theoretical predictions once the analysis accounted for the resistance heating of the solenoid. The noted differences between experimental results and theory could also be attributed to impeded slug motion from shear and mass forces. Within the workable pressure range, however, an optimal slug length was found which appropriately balances the pressure, shear, and magnetic forces in the system. This paper presents the experimental data on the dynamics and the maximum pressure differential generated by a LOX slug in a magnetic field and discusses the viability of LOX in a magnetic fluid management system intended for space applications.

  3. Slug responses to grassland cutting and fertilizer application under plant functional group removal

    Science.gov (United States)

    Everwand, Georg; Scherber, Christoph; Tscharntke, Teja

    2013-04-01

    Current studies on trophic interactions in biodiversity experiments have largely relied on artificially sown gradients in plant diversity, but removal experiments with their more natural plant community composition are more realistic. Slugs are a major part of the invertebrate herbivore community, with some species being common pests in agriculture. We therefore investigated how strongly slugs are influenced by grassland management, plant biodiversity and composition. Here we analysed the effects of cutting frequency, fertilizer application and plant functional group composition on slug densities and their contribution to herbivory on Rumex acetosa in a removal experiment within a >100-year old grassland in Northern Germany. The experiment was laid out as a Latin rectangle with full factorial combinations of (i) plant functional group removal (3 levels) using herbicides, (ii) fertilizer application (2 levels) and (iii) cutting frequency (2 levels). The resulting 12 treatment combinations were replicated 6 times, resulting in 72 plots. We collected a total of 1020 individuals belonging to three species Arion distinctus (60.4% of individuals), Deroceras reticulatum (34.7%) and Arion lusitanicus (4.9%) using a cover board technique and additionally measured herbivore damage to R. acetosa. We found the highest slug abundance on plots with a low cutting frequency and high food resource availability (increased cover of forbs and taller vegetation). Fertilizer application had no significant effect on slug abundance, but caused higher herbivore damage to on R. acetosa, possibly as a result of increased tissue quality. The negative effect of higher cutting frequency on slug abundance was lowest in control plots with their naturally developed graminoid-forb communities (cutting reduced slug density by 6% in the control vs. 29% in herbicide plots). Our experiments therefore support the idea that more natural plant species compositions reduce the impact of disturbances (e

  4. Observation of solar radio bursts using swept-frequency radiospectrograph in 20 - 40 MHz band

    International Nuclear Information System (INIS)

    A new station for the observation of solar decametric radio bursts has been developed at Miyagi Vocational Training College in Tsukidate, Miyagi, Japan. Using the swept frequency radiospectrograph covering a frequency range from 20 MHz to 40 MHz within 200 msec, with bandwidth of 30 kHz, the radio outbursts from the sun have been currently monitored with colored dynamic spectrum display. After July 1982, successful observations provide the data which include all types of solar radio bursts such as type I, II, III, IV and V in the decametric wavelength range. In addition to these typical radio bursts, rising tone bursts with fast drift rate followed by strong type III bursts and a series of bursts repeating rising and falling tone bursts with slow drift rate have been observed. (author)

  5. Influence of Catalysis and Oxidation on Slug Calorimeter Measurements in Arc Jets

    Science.gov (United States)

    Nawaz, Anuscheh; Driver, Dave; TerrazasSalinas, Imelda

    2012-01-01

    Arc jet tests play a critical role in the characterization and certification of thermal protection materials and systems (TPS). The results from these arc jet tests feed directly into computational models of material response and aerothermodynamics to predict the performance of the TPS in flight. Thus the precise knowledge of the plasma environment to which the test material is subjected, is invaluable. As one of the environmental parameters, the heat flux is commonly measured. The measured heat flux is used to determine the plasma enthalpy through analytical or computational models. At NASA Ames Research Center (ARC), slug calorimeters of a geometrically similar body to the test article are routinely used to determine the heat flux. A slug calorimeter is a thermal capacitance-type calorimeter that uses the temperature rise in a thermally insulated slug to determine the heat transfer rate, see Figure 1(left). Current best practices for measuring the heat flux with a slug calorimeter are described in ASTM E457 - 96. Both the calorimeter body and slug are made of Oxygen Free High Conductivity Copper, and are cleaned before each run.

  6. An Investigation on the Void Fraction for upward Gas-Liquid Slug Flow in Vertical Pipe

    Institute of Scientific and Technical Information of China (English)

    夏国栋; 周芳德; 胡明胜

    2001-01-01

    In order to investigate the influence of the entrance effect on the spatial distribution of phases, the experiments on gas-liquid two-phase slug flow in a vertical pipe of 0.03m ID were carried out by using optical probes and an EKTAPRO 1000 high speed motion analyzer. It demonstrates that the radial profile of slug flow void fraction is parabolic. Influenced by the falling liquid film, the radial profile curve of liquid slug void fraction in the wake region is also parabolic. Since fully turbulent velocity distribution is built up in the developed region,the void fraction profile in this region is the saddle type. At given superficial liquid velocity, the liquid slug void fraction increases with gas velocity. The radial profiles of liquid slug void fraction at different axial locations are all saddle curves, but void fraction is obviously high around the centerline in the entrance region. The nearer the measuring station is from the entrance, the farther the peak location is away from the wall.

  7. Modelling and control of growing slugs in horizontal multiphase pipe flows

    Directory of Open Access Journals (Sweden)

    Steinar M. Elgsæter

    2006-07-01

    Full Text Available In this paper, the use of active control to restrict the length of growing slugs in horizontal pipelines is investigated. Specifically, the paper attempts to determine if such control can be attained with realistic measurements and actuators. Simulations in OLGA2000 show that a feedback controller can use measurements or estimates of slug length to control the growth of a slug in a horizontal pipeline by partially closing inlet or outlet chokes. A control-volume approach is used to develop a low-order model of inlet choke-slug growth dynamics based on mass- and impulse balances. The resulting model is a system of nonlinear differential-algebraic equations, which is suitable for observer-design. The tuned model is found to be in good agreement with experiments and OLGA2000-simulations. Linearizations of the model are found to be observable around realistic trajectories when rates and pressures at the inlet and outlet are measured. An extended Luenberger-observer is shown to give good estimates of slug length and -position in simulations even under model uncertainty.

  8. Slug tuner effect on the field stabilization of the drift tube linac

    Science.gov (United States)

    Kim, Han-Sung

    2015-02-01

    In a drift tube linac (DTL), the accelerating field is stabilized against external perturbation, through resonant coupling between each cell by using post couplers. For proper field stabilization tuning, the frequency band between the post mode and the cavity mode should be closed. In addition, the field profile along the beam axis of the highest post mode should be similar to that of the TM011 cavity mode. As a conventional method to correct the resonance frequency and to make the accelerating field flat, slug tuners are incorporated. We observed that the similarity of field profiles between the highest post mode and the TM011 cavity mode disappeared when the slug tuners were inserted too much into the DTL tank. To achieve field stabilization tuning, we limited the slug tuner insertion and used a tuning ring around each post coupler to tune the resonant frequency of the DTL tank. The details of the effect of a slug tuner on the field stabilization tuning and the solution to the resonant frequency tuning problem caused by limited slug insertion will be presented in this paper.

  9. Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

    Directory of Open Access Journals (Sweden)

    Sarah Phillips

    2014-05-01

    Full Text Available Perturbations in stem cell activity and differentiation can lead to developmental defects and cancer. We use an approach involving a quantitative model of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates mammary epithelial stem cell activity and differentiation in vivo. In the absence of SLUG, stem cells fail to transition into basal progenitor cells, while existing basal progenitor cells undergo luminal differentiation; together, these changes result in abnormal mammary architecture and defects in tissue function. Furthermore, we show that in the absence of SLUG, mammary stem cell activity necessary for tissue regeneration and cancer initiation is lost. Mechanistically, SLUG regulates differentiation and cellular plasticity by recruiting the chromatin modifier lysine-specific demethylase 1 (LSD1 to promoters of lineage-specific genes to repress transcription. Together, these results demonstrate that SLUG plays a dual role in repressing luminal epithelial differentiation while unlocking stem cell transitions necessary for tumorigenesis.

  10. Evaluation of near-critical overdamping effects in slug-test response

    Science.gov (United States)

    Weeks, Edwin P.; Clark, Arthur C.

    2013-01-01

    A slug test behaves as a harmonic oscillator, subject to both inertial effects and viscous damping. When viscous and inertial forces are closely balanced, the system is nearly critically damped, and water-level recovery is affected by inertial effects, but does not exhibit oscillation. These effects were investigated by use of type curves, generated both by modification of Kipp's (1985) computer program and by use of the Butler-Zhan (2004) model. Utility of the type curves was verified by re-analysis of the Regina slug test previously analyzed by Kipp. These type curves indicate that near-critical inertial effects result in early-time delayed water-level response followed by merger with, or more rapid recovery than, response for the fully damped case. Because of this early time response, slug tests in the moderately over-damped range are best analyzed using log-log type curves of (1 − H/H0) vs. Tt/. Failure to recognize inertial effects in slug test data could result in an over-estimate of transmissivity, and a too-small estimate of storage coefficient or too-large estimate of well skin. However, application of the widely used but highly empirical Hvorslev (1951) method to analyze both the Regina slug test and type-curve generated data indicate that such analyses provide T values within a factor of 2 of the true value.

  11. Water slug formation and motion in gas flow channels: the effects of geometry, surface wettability, and gravity.

    Science.gov (United States)

    Cheah, May J; Kevrekidis, Ioannis G; Benziger, Jay B

    2013-08-01

    Water emerging from ∼100 μm pores into millimeter-size gas flow channels forms drops that grow and become slugs which span the flow channel. Flowing gas causes the slugs to detach and move down the channel. The effect of channel geometry, surface wettability, and gravity on the formation and motion of water slugs has been analyzed using high-speed video images of the drops and differential pressure-time traces. Drops grow and appear, assuming a sequence of shapes that minimize the total interfacial energy of the gas-liquid and liquid-solid interfaces. The drops are initially spherical caps centered on the pore (the liquid contacts one wall). Above a certain size, the drops move to the corner, forming "corner drops" (the liquid contacts two walls). Corner drops grow across the channel, evolving into partial liquid bridges (drops confined by three walls), and finally the drops span the channel cross-section forming slugs (contacting all four walls). Smaller slugs are formed in channels with hydrophobic walls than in channels with hydrophilic walls. Smaller slugs are formed in channels with curved walls than in square or rectangular channels. Slugs move when the differential gas pressure overcomes the force to move the advancing and receding gas-liquid-solid contact lines of the slugs. Residual water left behind in corners by moving slugs reduces the barriers for drops to form slugs, causing the steady-state slug volumes to be smaller than those seen at start-up in dry channels.

  12. Risk evaluation of rock burst through theory of static and dynamic stresses superposition

    Institute of Scientific and Technical Information of China (English)

    李振雷; 蔡武; 窦林名; 何江; 王桂峰; 丁言露

    2015-01-01

    Rock burst is one of the most catastrophic dynamic hazards in coal mining. A static and dynamic stresses superposition-based (SDSS-based) risk evaluation method of rock burst was proposed to pre-evaluate rock burst risk. Theoretical basis of this method is the stress criterion incurring rock burst and rock burst risk is evaluated according to the closeness degree of the total stress (due to the superposition of static stress in the coal and dynamic stress induced by tremors) with the critical stress. In addition, risk evaluation criterion of rock burst was established by defining the “Satisfaction Degree” of static stress. Furthermore, the method was used to pre-evaluate rock burst risk degree and prejudge endangered area of an insular longwall face in Nanshan Coal Mine in China. Results show that rock burst risk is moderate at advance extent of 97 m, strong at advance extent of 97−131 m, and extremely strong (i.e. inevitable to occur) when advance extent exceeds 131 m (mining is prohibited in this case). The section of two gateways whose floor abuts 15−3 coal seam is a susceptible area prone to rock burst. Evaluation results were further compared with rock bursts and tremors detected by microseismic monitoring. Comparison results indicate that evaluation results are consistent with microseismic monitoring, which proves the method’s feasibility.

  13. The Fermi–GBM Three-year X-Ray Burst Catalog

    Science.gov (United States)

    Jenke, P. A.; Linares, M.; Connaughton, V.; Beklen, E.; Camero-Arranz, A.; Finger, M. H.; Wilson-Hodge, C. A.

    2016-08-01

    The Fermi Gamma-ray Burst Monitor (GBM) is an all-sky gamma-ray monitor well known in the gamma-ray burst (GRB) community. Although GBM excels in detecting the hard, bright extragalactic GRBs, its sensitivity above 8 keV and its all-sky view make it an excellent instrument for the detection of rare, short-lived Galactic transients. In 2010 March, we initiated a systematic search for transients using GBM data. We conclude this phase of the search by presenting a three-year catalog of 1084 X-ray bursts. Using spectral analysis, location, and spatial distributions we classified the 1084 events into 752 thermonuclear X-ray bursts, 267 transient events from accretion flares and X-ray pulses, and 65 untriggered gamma-ray bursts. All thermonuclear bursts have peak blackbody temperatures broadly consistent with photospheric radius expansion (PRE) bursts. We find an average rate of 1.4 PRE bursts per day, integrated over all Galactic bursters within about 10 kpc. These include 33 and 10 bursts from the ultra-compact X-ray binaries 4U 0614+09 and 2S 0918-549, respectively. We discuss these recurrence times and estimate the total mass ejected by PRE bursts in our Galaxy.

  14. Introduction to Optical Burst Switching

    OpenAIRE

    KERNÁCS János; SZILÁGYI Szabolcs

    2010-01-01

    Optical Burst Switching (OBS) isconsidered a popular switching paradigm for therealization of all-optical networks due to the balance itoffers between the coarse-grained Optical CircuitSwitching (OSC) and fine-grained Optical PacketSwitching (OPS). Given that the data are switched allopticallyat the burst level, Optical Burst Switchingcombines the transparency of Optical CircuitSwitching with the benefits of statistical multiplexingin Optical Packet Switching.

  15. BROADBAND SPECTRAL INVESTIGATIONS OF SGR J1550-5418 BURSTS

    Energy Technology Data Exchange (ETDEWEB)

    Lin Lin; Goegues, Ersin; Kaneko, Yuki [Faculty of Engineering and Natural Sciences, Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I Tuzla, Istanbul 34956 (Turkey); Baring, Matthew G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Granot, Jonathan [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Kouveliotou, Chryssa [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Van der Horst, Alexander; Watts, Anna L. [Astronomical Institute ' Anton Pannekoek' , University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Gruber, David; Von Kienlin, Andreas [Max-Planck-Institut fuer extraterrestrische Physik, Postfach 1312, D-85748 Garching bei Mnchen (Germany); Younes, George [USRA, National Space Science and Technology Center, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Gehrels, Neil, E-mail: linlin@sabanciuniv.edu [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2012-09-01

    We present the results of our broadband spectral analysis of 42 SGR J1550-5418 bursts simultaneously detected with the Swift/X-ray Telescope (XRT) and the Fermi/Gamma-ray Burst Monitor (GBM), during the 2009 January active episode of the source. The unique spectral and temporal capabilities of the XRT windowed timing mode have allowed us to extend the GBM spectral coverage for these events down to the X-ray domain (0.5-10 keV). Our earlier analysis of the GBM data found that the SGR J1550-5418 burst spectra were described equally well with either a Comptonized model or with two blackbody functions; the two models were statistically indistinguishable. Our new broadband (0.5-200 keV) spectral fits show that, on average, the burst spectra are better described with two blackbody functions than with the Comptonized model. Thus, our joint XRT-GBM analysis clearly shows for the first time that the SGR J1550-5418 burst spectra might naturally be expected to exhibit a more truly thermalized character, such as a two-blackbody or even a multi-blackbody signal. Using the Swift and RXTE timing ephemeris for SGR J1550-5418 we construct the distribution of the XRT burst counts with spin phase and find that it is not correlated with the persistent X-ray emission pulse phase from SGR J1550-5418. These results indicate that the burst emitting sites on the neutron star need not to be co-located with hot spots emitting the bulk of the persistent X-ray emission. Finally, we show that there is a significant pulse phase dependence of the XRT burst counts, likely demonstrating that the surface magnetic field of SGR J1550-5418 is not uniform over the emission zones, since it is anticipated that regions with stronger surface magnetic field could trigger bursts more efficiently.

  16. Broadband Spectral Investigations of SGR J1550-5418 Bursts

    Science.gov (United States)

    Lin, Lin; Goegues, Ersin; Baring, Matthew G.; Granot, Jonathan; Kouveliotou, Chryssa; Kaneko, Yuki; van der Horst, Alexander; Gruber, David; von Kienlin, Andreas; Younes, George; Watts, Anna L.; Gehrels, Neil

    2012-01-01

    We present the results of our broadband spectral analysis of 42 SGR J1550-5418 bursts simultaneously detected with the Swift/X-ray Telescope (XRT) and the Fermi/Gamma-ray Burst Monitor (GBM), during the 2009 January active episode of the source. The unique spectral and temporal capabilities of the XRT windowed timing mode have allowed us to extend the GBM spectral coverage for these events down to the X-ray domain (0.5-10 keV). Our earlier analysis of the GBM data found that the SGR J1550-5418 burst spectra were described equally well with either a Comptonized model or with two blackbody functions; the two models were statistically indistinguishable. Our new broadband (0.5-200 keV) spectral fits show that, on average, the burst spectra are better described with two blackbody functions than with the Comptonized model. Thus, our joint XRT-GBM analysis clearly shows for the first time that the SGR J1550-5418 burst spectra might naturally be expected to exhibit a more truly thermalized character, such as a two-blackbody or even a multi-blackbody signal. Using the Swift and RXTE timing ephemeris for SGR J1550-5418 we construct the distribution of the XRT burst counts with spin phase and find that it is not correlated with the persistent X-ray emission pulse phase from SGR J1550-5418. These results indicate that the burst emitting sites on the neutron star need not to be co-located with hot spots emitting the bulk of the persistent X-ray emission. Finally, we show that there is a significant pulse phase dependence of the XRT burst counts, likely demonstrating that the surface magnetic field of SGR J1550-5418 is not uniform over the emission zones, since it is anticipated that regions with stronger surface magnetic field could trigger bursts more efficiently.

  17. Gamma-ray burst spectra

    Science.gov (United States)

    Teegarden, B. J.

    1982-01-01

    A review of recent results in gamma-ray burst spectroscopy is given. Particular attention is paid to the recent discovery of emission and absorption features in the burst spectra. These lines represent the strongest evidence to date that gamma-ray bursts originate on or near neutron stars. Line parameters give information on the temperature, magnetic field and possibly the gravitational potential of the neutron star. The behavior of the continuum spectrum is also discussed. A remarkably good fit to nearly all bursts is obtained with a thermal-bremsstrahlung-like continuum. Significant evolution is observed of both the continuum and line features within most events.

  18. BP-5 Remedial Investigation Slug-Test Characterization Results for Well 699-52-55A

    Energy Technology Data Exchange (ETDEWEB)

    Newcomer, Darrell R.

    2008-07-21

    Pacific Northwest National Laboratory conducted slug-test characterization at the final, completed BP-5 Remedial Investigation well 699-52-55A near the 200-East Area at the Hanford Site on April 22, 2008. The slug-test characterization was in support of the BP-5 Remedial Investigation. The portion of the unconfined aquifer tested is composed of sediments of the lower Ringold Formation and the underlying Elephant Mountain basalt flowtop. The basalt flowtop unit was included as part of the effective test-interval length for the slug-test analysis because the flowtop unit is hydraulically communicative with the unconfined aquifer. Estimates of hydraulic conductivity for the effective test-interval length represent composite values for the lower Ringold Formation and the underlying Elephant Mountain basalt flow top.

  19. The Slug Mucosal Irritation (SMI) assay: a tool for the evaluation of nasal discomfort.

    Science.gov (United States)

    Lenoir, Joke; Bachert, Claus; Remon, Jean-Paul; Adriaens, Els

    2013-09-01

    In this research project, the Slug Mucosal Irritation (SMI) assay was applied to predict nasal discomfort, investigating the correlation between responses in slugs and humans. Several SMI experiments and a Human Nose Irritation Test (HNIT) were performed with five NaCl solutions (0.4%, 1.3%, 2.6%, 5.4% and 10.4%) and two benzalkonium chloride solutions (BAC 0.02% and BAC 0.05%). In the HNIT, subjective evaluation of clinical discomfort was performed by 24 participants at several time points. Analyzes reveal that (1) a significant positive association existed between immediate stinging reaction reported by the participants and the mean total mucus production of the slugs (Spearman's Rank correlation=0.963, pSMI assay is a promising evaluation method for clinical nasal discomfort. Screening (prototype) formulations with this assay allows formula optimization prior to a clinical trial.

  20. Applicability of slug interference tests under Hanford Site test conditions: Analytical assessment and field test evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Spane, F.A. Jr.

    1992-04-01

    Slug interference testing may be a useful technique for characterizing the hydraulic properties of high conductivity formations where problems associated with disposal of contaminated ground water make pumping tests undesirable. The suitability of the slug interference method for characterizing the unconfined aquifer at the Hanford Site was evaluated in a two-phase investigation. The first phase consisted of an analytical assessment. Slug interference responses were predicted over the range of conditions expected for the aquifer. The effects of partial penetration, delayed-yield and aquifer anisotropy on expected test results were also evaluated and possible analytical corrections are presented. The field test evaluation was conducted at a site with two observation wells and a stress well. Results verified the analytical evaluation and gave reasonable values of hydraulic conductivity and storativity. Test design considerations that optimize the observed response are discussed.

  1. Dark Gamma Ray Bursts

    OpenAIRE

    Brdar, Vedran; Kopp, Joachim; Liu, Jia

    2016-01-01

    Many theories of dark matter (DM) predict that DM particles can be captured by stars via scattering on ordinary matter. They subsequently condense into a DM core close to the center of the star and eventually annihilate. In this work, we trace DM capture and annihilation rates throughout the life of a massive star and show that this evolution culminates in an intense annihilation burst coincident with the death of the star in a core collapse supernova. The reason is that, along with the stell...

  2. Gamma Ray Bursts

    Science.gov (United States)

    Gehrels, Neil; Meszaros, Peter

    2012-01-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma-rays coming from the cosmos. They occur roughly once per day ,last typically lOs of seconds and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this review we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglows.

  3. Gamma-Ray Bursts

    Science.gov (United States)

    Gehrels, Neil; Mészáros, Péter

    2012-08-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma rays coming from the cosmos. They occur roughly once per day, typically last for tens of seconds, and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this Review, we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglow.

  4. Gamma Ray Bursts

    CERN Document Server

    Gehrels, Neil; 10.1126/science.1216793

    2012-01-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma-rays coming from the cosmos. They occur roughly once per day, last typically 10s of seconds and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this review we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglows.

  5. Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions.

    Science.gov (United States)

    Cech, Jiří; Přibyl, Michal; Snita, Dalimil

    2013-01-01

    Here, we introduce a solution to low stability of a two-phase slug flow with a chemical reaction occurring at the phase interface in a microfluidic reactor where substantial merging of individual reacting slugs results in the loss of uniformity of the flow. We create a three-phase slug flow by introducing a third fluid phase into the originally two-phase liquid-liquid slug flow, which generates small two-phase liquid slugs separated by gas phase. Introduction of the third phase into our system efficiently prevents merging of slugs and provides beneficial reaction conditions, such as uniform flow pattern along the whole reaction capillary, interfacial area with good reproducibility, and intensive water-oil interface renewal. We tested the three-phase flow on an enzyme hydrolysis of soybean oil and compared the reaction conversion with those from unstable two-phase slug flows. We experimentally confirmed that the three-phase slug flow arrangement provides conversions and pressure drops comparable or even better with two-phase liquid-liquid arrangements.

  6. The Gastropod Menace: Slugs on Brassica Plants Affect Caterpillar Survival through Consumption and Interference with Parasitoid Attraction.

    Science.gov (United States)

    Desurmont, Gaylord A; Zemanova, Miriam A; Turlings, Ted C J

    2016-03-01

    Terrestrial molluscs and insect herbivores play a major role as plant consumers in a number of ecosystems, but their direct and indirect interactions have hardly been explored. The omnivorous nature of slugs makes them potential disrupters of predator-prey relationships, as a direct threat to small insects and through indirect, plant-mediated effects. Here, we examined the effects of the presence of two species of slugs, Arion rufus (native) and A. vulgaris (invasive) on the survivorship of young Pieris brassicae caterpillars when feeding on Brassica rapa plants, and on plant attractiveness to the main natural enemy of P. brassicae, the parasitoid Cotesia glomerata. In two separate predation experiments, caterpillar mortality was significantly higher on plants co-infested with A. rufus or A. vulgaris. Moreover, caterpillar mortality correlated positively with slug mass and leaf consumption by A. vulgaris. At the third trophic level, plants infested with slugs and plants co-infested with slugs and caterpillars were far less attractive to parasitoids than plants damaged by caterpillars only, independently of slug species. Chemical analyses confirmed that volatile emissions, which provide foraging cues for parasitoids, were strongly reduced in co-infested plants. Our study shows that the presence of slugs has the potential to affect insect populations, directly via consumptive effects, and indirectly via changes in plant volatiles that result in a reduced attraction of natural enemies. The fitness cost for P. brassicae imposed by increased mortality in presence of slugs may be counterbalanced by the benefit of escaping its parasitoids. PMID:27002323

  7. Image processing analysis on the air-water slug two-phase flow in a horizontal pipe

    Science.gov (United States)

    Dinaryanto, Okto; Widyatama, Arif; Majid, Akmal Irfan; Deendarlianto, Indarto

    2016-06-01

    Slug flow is a part of intermittent flow which is avoided in industrial application because of its irregularity and high pressure fluctuation. Those characteristics cause some problems such as internal corrosion and the damage of the pipeline construction. In order to understand the slug characteristics, some of the measurement techniques can be applied such as wire-mesh sensors, CECM, and high speed camera. The present study was aimed to determine slug characteristics by using image processing techniques. Experiment has been carried out in 26 mm i.d. acrylic horizontal pipe with 9 m long. Air-water flow was recorded 5 m from the air-water mixer using high speed video camera. Each of image sequence was processed using MATLAB. There are some steps including image complement, background subtraction, and image filtering that used in this algorithm to produce binary images. Special treatments also were applied to reduce the disturbance effect of dispersed bubble around the bubble. Furthermore, binary images were used to describe bubble contour and calculate slug parameter such as gas slug length, gas slug velocity, and slug frequency. As a result the effect of superficial gas velocity and superficial liquid velocity on the fundamental parameters can be understood. After comparing the results to the previous experimental results, the image processing techniques is a useful and potential technique to explain the slug characteristics.

  8. Naturally-Forced Slug Flow Expander for Application in a Waste-Heat Recovery Cycle

    Directory of Open Access Journals (Sweden)

    Ben de Witt

    2014-11-01

    Full Text Available This paper investigates a slug-flow expander (SFE for conversion of high-pressure gas/vapor into kinetic energy of liquid slugs. The energy transfer from high-pressure to kinetic energy is quantified using thrust plate measurements. Non-dimensional thrust data is used to quantify performance by normalizing measured thrust by thrust for the same water flow rate at zero air flow rate. A total of 13 expander configurations are investigated and geometries with the shortest cavity length and the smallest exit diameter are found to result in the largest non-dimensional thrust increase. Results show that thrust augmentation increases with the initiation of slug flow in the SFE. The analysis performed on the normalized thrust readings suggested that as the water and air flow were increased to critical conditions, the liquid slugs produced by the SFE augmented the thrust measurements. The final performance evaluation was based on linear regression of the normalized thrust measurements where slug flow was generated for each SFE architecture. Greater magnitudes of the slope from the linear regression indicated the propensity of the SFE to augment thrust. This analysis confirmed that for the SFE configurations over the range of values investigated, the SFE increased thrust up to three times its original value at no air flow. Given the inherent multiphase nature of the slug-flow expander, application to systems involving expansion of wetting fluids (water as part of a waste-heat recovery system or air with water droplet formation (as part of a compressed-air energy storage system could be considered.

  9. A localized differentiation-inducing-factor sink in the front of the Dictyostelium slug.

    OpenAIRE

    Kay, R R; Large, S.; Traynor, D.; Nayler, O

    1993-01-01

    Differentiation-inducing factor 1 [DIF-1; 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-hexan-1-one] induces stalk cell differentiation during Dictyostelium development. It is present as a gradient in the multicellular slug, its lowest concentration being in the anterior. Here we demonstrate the existence of a localized sink for DIF-1, also in the anterior of the slug, which could be responsible for generating the DIF-1 gradient. DIF-1 is metabolized extensively by developing cells, initiall...

  10. Dark Gamma Ray Bursts

    CERN Document Server

    Brdar, Vedran; Liu, Jia

    2016-01-01

    Many theories of dark matter (DM) predict that DM particles can be captured by stars via scattering on ordinary matter. They subsequently condense into a DM core close to the center of the star and eventually annihilate. In this work, we trace DM capture and annihilation rates throughout the life of a massive star and show that this evolution culminates in an intense annihilation burst coincident with the death of the star in a core collapse supernova. The reason is that, along with the stellar interior, also its DM core heats up and contracts, so that the DM density increases rapidly during the final stages of stellar evolution. We argue that, counterintuitively, the annihilation burst is more intense if DM annihilation is a p-wave process than for s-wave annihilation because in the former case, more DM particles survive until the supernova. If among the DM annihilation products are particles like dark photons that can escape the exploding star and decay to Standard Model particles later, the annihilation bu...

  11. Monitor

    Data.gov (United States)

    US Agency for International Development — A custom-built, dual-language (English and Spanish) system (http://www.monitor.net.co/) developed by DevTech that debuted in January 2011. It features a central PMP...

  12. Burst Mode Transmission in GPON

    Institute of Scientific and Technical Information of China (English)

    LI Liang-chuan; ZHANG Yan-gan; LI Ling; XU Da-xiong

    2004-01-01

    In this paper, a newly approved standard G.984 for Gigabit-capable Passive Optical Networks (GPON) is introduced. Technical challenges about high-speed burst-mode data transmission in GPON are discussed and key issues such as Forward Error Correction (FEC), timing to uplink performance of burst mode are high-lighted.

  13. Short duration gamma ray bursts

    Indian Academy of Sciences (India)

    Patrick Das Gupta

    2004-10-01

    After a short review of gamma ray bursts (GRBs), we discuss the physical implications of strong statistical correlations seen among some of the parameters of short duration bursts (90 < 2 s). Finally, we conclude with a brief sketch of a new unified model for long and short GRBs.

  14. Thermonuclear bursts from slowly and rapidly accreting neutron stars

    Science.gov (United States)

    Linares, Manuel

    2012-07-01

    Models of thermonuclear burning on accreting neutron stars predict different ignition regimes, depending mainly on the mass accretion rate per unit area. For more than three decades, testing these regimes observationally has met with only partial success. I will present recent results from the Fermi-GBM all-sky X-ray burst monitor, which is yielding robust measurements of recurrence time of rare and highly energetic thermonuclear bursts at the lowest mass accretion rates. I will also present RXTE observations of thermonuclear bursts at high mass accretion rates, including the discovery of millihertz quasi-periodic oscillations and several bursting regimes in a neutron star transient and 11 Hz X-ray pulsar. This unusual neutron star, with higher magnetic field and slower rotation than any other known burster, showed copious bursting activity when the mass accretion rate varied between 10% and 50% of the Eddington rate. I will discuss the role of fuel composition and neutron star spin in setting the burst properties of this system, and the possible implications for the rest of thermonuclear bursters.

  15. Bursts de raios gama

    Science.gov (United States)

    Braga, J.

    2003-02-01

    Nos últimos anos, graças principalmente aos dados obtidos pelo Compton Gamma-Ray Observatory e pelo satélite ítalo-holandês BeppoSAX, grandes avanços foram obtidos no nosso conhecimento sobre os fascinantes e enigmáticos fenômenos conhecidos por "bursts"de raios gama. Neste trabalho é feita uma revisão sobre a fenomenologia desses misteriosos objetos e são apresentados os desenvolvimentos recentes nessa área palpitante da astrofísica moderna, ressaltando tanto os resultados observacionais obtidos até o momento quanto os modelos teóricos propostos para explixá-los.

  16. Development of Liquid Slug Length in Gas-Liquid Slug Flow along Horizontal Pipeline: Experiment and Simulation%水平管内气液段塞流液塞长度发展规律的实验和模拟研究

    Institute of Scientific and Technical Information of China (English)

    王鑫; 郭烈锦; 张西民

    2006-01-01

    The liquid slug length distribution is crucial for designing the downstream processing system with multiphase pipeline. Experiments were conducted in a 133m long horizontal test loop. The measurements were performed by conductivity probes to determine the liquid slug length distribution. The data covered both the slug and plug flow regimes. From experimental results, the mean liquid slug lengths were relatively insensitive to gas and liquid flow rates in the higher mixture velocity range. But in the lower mixture velocity range, the mean liquid slug length decreased and then increased with mixture velocity. It shows that the development length of slug flow was longer than χ/D=1157. A slug tracking model was adapted to study the evolution of liquid slug length distribution in a horizontal pipeline. In the present model, the wake effect of elongated bubble and the pressure drop due to acceleration are taken into account and random slug lengths are introduced at the entrance. The results of the model are compared with the measured slug length distributions of slug flow regime. It shows that the predicted mean and maximum slug lengths are in agreement with the experimental data at x/D=1157 and the form of the slug length distributions is also predicted well by the model.

  17. Draft Genome Sequence of Hawaiian Sea Slug Symbiont Vibrio sp. Strain ER1A

    OpenAIRE

    Davis, Jeanette; Hill, Russell T.

    2014-01-01

    Bacteria belonging to the genus Vibrio are prevalent in the marine environment and are known for forming symbiotic relationships with hosts. Vibrio sp. strain ER1A is a dominant symbiont of the Hawaiian sea slug, Elysia rufescens. Here we report the draft genome sequence of Vibrio sp. ER1A.

  18. Acquired phototrophy through retention of functional chloroplasts increases growth efficiency of the sea slug Elysia viridis.

    Directory of Open Access Journals (Sweden)

    Finn A Baumgartner

    Full Text Available Photosynthesis is a fundamental process sustaining heterotrophic organisms at all trophic levels. Some mixotrophs can retain functional chloroplasts from food (kleptoplasty, and it is hypothesized that carbon acquired through kleptoplasty may enhance trophic energy transfer through increased host growth efficiency. Sacoglossan sea slugs are the only known metazoans capable of kleptoplasty, but the relative fitness contributions of heterotrophy through grazing, and phototrophy via kleptoplasts, are not well understood. Fitness benefits (i.e. increased survival or growth of kleptoplasty in sacoglossans are commonly studied in ecologically unrealistic conditions under extended periods of complete darkness and/or starvation. We compared the growth efficiency of the sacoglossan Elysia viridis with access to algal diets providing kleptoplasts of differing functionality under ecologically relevant light conditions. Individuals fed Codium fragile, which provide highly functional kleptoplasts, nearly doubled their growth efficiency under high compared to low light. In contrast, individuals fed Cladophora rupestris, which provided kleptoplasts of limited functionality, showed no difference in growth efficiency between light treatments. Slugs feeding on Codium, but not on Cladophora, showed higher relative electron transport rates (rETR in high compared to low light. Furthermore, there were no differences in the consumption rates of the slugs between different light treatments, and only small differences in nutritional traits of algal diets, indicating that the increased growth efficiency of E. viridis feeding on Codium was due to retention of functional kleptoplasts. Our results show that functional kleptoplasts from Codium can provide sacoglossan sea slugs with fitness advantages through photosynthesis.

  19. Severe slugging in gas-liquid two-phase pipe flow

    NARCIS (Netherlands)

    Malekzadeh, R.

    2012-01-01

    transportation facilities. In an offshore oil and gas production facility, pipeline-riser systems are required to transport two-phase hydrocarbons from subsurface oil and gas wells to a central production platform. Severe slugs reaching several thousands pipe diameters may occur when transporting g

  20. Transient drift flux modelling of severe slugging in pipeline-riser systems

    NARCIS (Netherlands)

    Malekzadeh, R.; Belfroid, S.P.C.; Mudde, R.F.

    2012-01-01

    A large number of pipelines in the petroleum industry simultaneously transport gas and liquid. Transient behaviour of multiphase flow is frequently encountered in these pipelines. A common example is severe slugging that can occur in multiphase flow systems where a pipeline segment with a downward o

  1. Influence of riser-induced slugs on the downstream separation processes

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2016-01-01

    gives the best average production rate. Furthermore, it is confirmed that a PWT-ecient riser bottom pressure (Prb) anti-slug control strategy has to guarantee stabilization of the mass inflow rate to the separator for archiving acceptable hydrocyclone separation. A stable !sep;in is observed...... not to be directly linked to a stable Prb....

  2. On the hydrodynamics of liquid–liquid slug flow capillary microreactors

    NARCIS (Netherlands)

    Kashid, M.N.; Fernandez Rivas, D.; Agar, D.W.; Turek, S.

    2008-01-01

    Microreactor technology is an important method of process intensification. Liquid–liquid slug flow capillary microreactors have been used to intensify the reactions with heat and mass transfer limitations. In this type of reactor, either two liquids flow alternate to each other in a capillary or one

  3. Experimental investigation of terrain slugging formation, evolution and potential for mitigation

    NARCIS (Netherlands)

    Brasjen, B.J.; Hansen, J.H.; Schiferli, W.; Belfroid, S.P.C.

    2013-01-01

    The formation and evolution of slugs formed in air/water mixture in inclined pipes has been characterized as a function of flow conditions, pipe length and inclination angle. Good agreement was found with model predictions and experimental observations available from literature. Two regimes were ide

  4. Lactic Acid Extraction and Mass Transfer Characteristics in Slug Flow Capillary Microreactors

    NARCIS (Netherlands)

    Susanti,; Winkelman, Jozef G.M.; Schuur, Boelo; Heeres, Hero J.; Yue, Jun

    2016-01-01

    Capillary microreactors operated under the slug flow regime were investigated for the separation of lactic acid from the aqueous phase using liquid–liquid reactive extraction. The experiments were performed at a 1:1 flow ratio of the aqueous to organic phases in a setup consisting of an inlet Y-type

  5. Why it is time to look beyond algal genes in photosynthetic slugs

    NARCIS (Netherlands)

    C. Rauch (Cessa); J. de Vries (Jan); S. Rommel (Sophie); L.E. Rose (Laura E.); C. Woehle (Christian); G. Christa (Gregor); E.M. Laetz (Elise M.); H. Wägele (Heike); A.G.M. Tielens (Aloysius); J. Nickelsen (Jörg); T. Schumann (Tobias); P. Jahns (Peter); D.B. Gould (Douglas )

    2015-01-01

    textabstractEukaryotic organelles depend on nuclear genes to perpetuate their biochemical integrity. This is true for mitochondria in all eukaryotes and plastids in plants and algae. Then how do kleptoplasts, plastids that are sequestered by some sacoglossan sea slugs, survive in the animals' digest

  6. The Fermi GBM gamma-ray burst time-resolved spectral catalog: brightest bursts in the first four years

    CERN Document Server

    Yu, Hoi-Fung; Greiner, Jochen; Bhat, P Narayana; Bissaldi, Elisabetta; Briggs, Michael S; Cleveland, William H; Connaughton, Valerie; Goldstein, Adam; von Kienlin, Andreas; Kouveliotou, Chryssa; Mailyan, Bagrat; Meegan, Charles A; Paciesas, William S; Rau, Arne; Roberts, Oliver J; Veres, Péter; Wilson-Hodge, Colleen; Zhang, Bin-Bin; van Eerten, Hendrik J

    2016-01-01

    We aim to obtain high-quality time-resolved spectral fits of gamma-ray bursts (GRBs) observed by the Gamma-ray Burst Monitor (GBM) on board the Fermi Gamma-ray Space Telescope. We perform time-resolved spectral analysis with high temporal and spectral resolution of the brightest bursts observed by Fermi GBM in its first 4 years of mission. We present the complete catalog containing 1,491 spectra from 81 bursts with high spectral and temporal resolution. Distributions of parameters, statistics of the parameter populations, parameter-parameter and parameter-uncertainty correlations, and their exact values are obtained and presented as main results in this catalog. We report a criterion that is robust enough to automatically distinguish between different spectral evolutionary trends between bursts. We also search for plausible blackbody emission components and find that only 3 bursts (36 spectra in total) show evidence of a pure Planck function. It is observed that the averaged time-resolved low-energy power-law...

  7. MicroRNA-1(miR-1) inhibits chordoma cell migration and invasion by targeting Slug

    Science.gov (United States)

    Osaka, Eiji; Yang, Xiaoqian; Shen, Jacson K.; Yang, Pei; Feng, Yong; Mankin, Henry J.; Hornicek, Francis J.; Duan, Zhenfeng

    2014-01-01

    Recent studies have revealed that expression of miRNA-1(miR-1) is frequently downregulated in several cancer types including chordoma. Identifying and validating novel targets of miR-1 is useful for understanding the roles of miR-1 in chordoma. We aimed to further investigate the functions of miR-1 in chordoma. Specifically, we assessed whether restoration of miR-1 affects cell migration and invasion in chordoma, and focused on the miR-1 potential target Slug gene. Migratory and invasive activities were assessed by wound healing and Matrigel invasion assays, respectively. Cell proliferation was determined by MTT assay. Slug expression was evaluated by Western blot, immunofluorescence, and immunohistochemistry. Restoration of miR-1 expression suppressed the migratory and invasive activities of chordoma cells. Transfection of miR-1 inhibited cell proliferation both time- and dose-dependently in chordoma. miR-1 transfected cells showed inhibited Slug expression. Slug was overexpressed in chordoma cell lines and advanced chordoma tissues. In conclusion, we have shown that miR-1 directly targets the Slug gene in chordoma. Restoration of miR-1 suppressed not only proliferation, but also migratory and invasive activities, and reduced the Slug expression in chordoma cells. These results collectively indicate that miR-1/Slug pathway is a potential therapeutic target because of its crucial roles in chordoma cell growth and migration. PMID:24760686

  8. Identification of a nonlinear groundwater flow at a slug test in fractured rock and its influence on the test

    Science.gov (United States)

    Ji, S.; Koh, Y.

    2013-12-01

    Many laboratory and numerical studies reported that a groundwater flow through a fracture at sufficiently high Reynolds numbers does not obey the cubic law which assumes a linear relation between the hydraulic gradient and the flux. Most of them observed that the transitions from a linear to nonlinear flow arose at the Reynolds numbers greater than 10. A slug test is one of the common hydraulic tests, and used for estimation of the hydraulic properties of an aquifer by analyzing the recovery after a sudden change in hydraulic pressure. In this study, we conducted a series of slug tests with various initial head displacements at an experimental borehole at KAERI's (Korea Atomic Energy Research Institute) underground research tunnel whose host rock is Jurassic granite. The Reynolds number at a fracture during slug tests was calculated using the geophysical logging data and slug test results, and the nonlinear flow regime at slug tests was identified. From changes in the Reynolds number during the tests and estimates of the hydraulic properties from the tests, the influence of a nonlinear flow on a slug test was discussed. Our results indicate that the nonlinearity of groundwater flow at a slug test became more severe and the estimated hydraulic conductivity decreased as the initial head displacement increased.

  9. Monitoring

    Science.gov (United States)

    ... its main source of fuel. To keep your blood sugar level on target and avoid problems with your eyes, kidneys, heart and feet, you should eat right ... better. And monitoring doesn’t stop at measuring blood sugar levels. Because ... blood testing) Eye health (eye exams) Foot health (foot exams and ...

  10. Severe slugging in a flexible S-shaped riser system: Experimental studies and transient simulation

    Science.gov (United States)

    Li, Wensheng; Guo, Liejin; Li, Nailiang

    2013-07-01

    Severe slugging, which could induce large-amplitude pressure and flow rate fluctuations, is a major and expensive problem in multiphase transportation systems of offshore oil production system. To avoid such problem is a basic requirement for flow assurance management. This study is an experimental and numerical investigation of severe slugging in a relatively long pipeline-riser system. A series of experiments on two-phase, air-water flow in a flexible Sshaped riser were carried out. The experimental system has a 114m long horizontal pipeline connected to a 19m long pipe which is inclined to -2degree from horizontal, followed by a 15.3m high riser operating at atmospheric end pressure. Four types of flow patterns were found and characterized by the pressure fluctuations at the bottom of the riser. A flow patter map for the prediction of severe slugging was developed based on the experimental results. The detailed characteristics of severe slugging such as pressure fluctuations, liquid holdup, under different gas-liquid superficial velocities were provided. A transient model to predict the flow behavior in the pipeline-S-shaped riser system was developed based on an existing model (OLGA). The modified model, which was tested against new experimental results obtained in this study, showed that the four types of flow patterns observed in the experiment were predicted with acceptable discrepancies. The flow pattern map was obtained using present model, as well as the detailed characteristics of severe slugging. In addition, the reasons for the difference between experimental and numerical results were analysed in this article. The motive of the numerical studies was to identify the areas that could not be reproduced by the present model and to give some suggestions for future models.

  11. Posttranslationally caused bioluminescence burst of the Escherichia coli luciferase reporter strain.

    Science.gov (United States)

    Ideguchi, Yamato; Oshikoshi, Yuta; Ryo, Masashi; Motoki, Shogo; Kuwano, Takashi; Tezuka, Takafumi; Aoki, Setsuyuki

    2016-01-01

    We continuously monitored bioluminescence from a wild-type reporter strain of Escherichia coli (lacp::luc+/WT), which carries the promoter of the lac operon (lacp) fused with the firefly luciferase gene (luc+). This strain showed a bioluminescence burst when shifted into the stationary growth phase. Bioluminescence profiles of other wild-type reporter strains (rpsPp::luc+ and argAp::luc+) and gene-deletion reporter strains (lacp::luc+/crp- and lacp::luc+/lacI-) indicate that transcriptional regulation is not responsible for generation of the burst. Consistently, changes in the luciferase protein levels did not recapitulate the profile of the burst. On the other hand, dissolved oxygen levels increased over the period across the burst, suggesting that the burst is, at least partially, caused by an increase in intracellular oxygen levels. We discuss limits of the firefly luciferase when used as a reporter for gene expression and its potential utility for monitoring metabolic changes in cells.

  12. Concept for LEU Burst Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Steven Karl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kimpland, Robert Herbert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-07

    Design and performance of a proposed LEU burst reactor are sketched. Salient conclusions reached are the following: size would be ~1,500 kg or greater, depending on the size of the central cavity; internal stresses during burst require split rings for relief; the reactor would likely require multiple control and safety rods for fine control; the energy spectrum would be comparable to that of HEU machines; and burst yields and steady-state power levels will be significantly greater in an LEU reactor.

  13. Numerical investigation of temporal changes in volcanic deformation caused by a gas slug ascent in the conduit

    Science.gov (United States)

    Kawaguchi, Ryohei; Nishimura, Takeshi

    2015-09-01

    Strombolian type eruptions are considered to be generated by a sudden release of a large gas slug that migrates upward in the conduit filled with a low viscous basaltic magma. We examine volcano deformations caused by such a gas slug to understand the Strombolian eruption mechanism from geodetic observation data. We model spatio-temporal pressure changes in the conduit by using a gas slug ascent model presented by James et al. (2008). As a gas slug ascends in the conduit, its volume expands because of depressurization. Hence, the magma head lifts up in the conduit and the upper part of the conduit wall is stressed. In the conduit, magma pressure increases with depth according to the bulk density of magma: the gas slug part with a low density is characterized by a small pressure gradient, while the other parts, consisting of melt, are characterized by a large pressure gradient. We numerically calculate volcano deformations caused by the spatio-temporal changes of magma pressure predicted from the basic equations representing gas slug locations in the conduit. Simulation results show that the radial and vertical displacements and tilt changes indicate volcano deformations that represent the inflation originating from the stress increase at the upper part of conduit. As the gas slug reaches the shallow part of conduit, the rate of inflation observed in the radial displacement decreases, the vertical displacement starts to move downward, and the tilt turns to show down toward the crater. These deflation signals are caused by a moving deflation source in the conduit that is formed beneath the gas slug. Since these predicted features are not observed in the tilt records associated with explosions at Stromboli volcano (Genco and Ripepe, 2010), it is necessary to modify the gas slug ascent model or to introduce other mechanisms to better understand the magma dynamics of Strombolian eruption.

  14. Learning control for riser-slug elimination and production-rate optimization for an offshore oil and gas production process

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2014-01-01

    Slugging flow in the offshore oil & gas production attracts lot of attention due to it's limitation of production rate, periodic overload on processing facilities, and even direct cause of emergency shutdown. This work aims at two correlated objectives: (i) Preventing slugging flow; and meanwhile......, (ii) maximizing the production rate at the riser of an offshore production platform, by manipulating a topside choke valve through a learning switching model-free PID controller. The results show good steady-state performance, though a long settling time due to the unknown reference for no slugging...

  15. SWIFT and BATSE bursts' classification

    CERN Document Server

    Horvath, I; Balazs, L G; Tusnady, G; Veres, P

    2009-01-01

    Two classes of gamma-ray bursts were identified in the BATSE catalogs characterized by their durations. There were also some indications for the existence of a third type of gamma-ray bursts. Swift satellite detectors have different spectral sensitivity than pre-Swift ones for GRBs. Therefore in this paper we analyze the bursts' duration distribution and also the duration-hardness bivariate distribution, published in The First BAT Catalog. Similarly to the BATSE data, to explain the BAT GRBs' duration distribution three components are needed. Although, the relative frequencies of the groups are different than they were in the BATSE GRB sample, the difference in the instrument spectral sensitivities can explain this bias in a natural way. This means theoretical models may have to explain three different type of gamma-ray bursts.

  16. FERMIGBRST - Fermi GBM Burst Catalog

    Data.gov (United States)

    National Aeronautics and Space Administration — This table lists all of the triggers observed by a subset of the 14 GBM detectors (12 NaI and 2 BGO) which have been classified as gamma-ray bursts (GRBs). Note...

  17. Chimera states in bursting neurons

    OpenAIRE

    Bera, Bidesh K.; Ghosh, Dibakar; Lakshmanan, M.

    2015-01-01

    We study the existence of chimera states in pulse-coupled networks of bursting Hindmarsh-Rose neurons with nonlocal, global and local (nearest neighbor) couplings. Through a linear stability analysis, we discuss the behavior of stability function in the incoherent (i.e. disorder), coherent, chimera and multi-chimera states. Surprisingly, we find that chimera and multi-chimera states occur even using local nearest neighbor interaction in a network of identical bursting neurons alone. This is i...

  18. Disinhibition Bursting of Dopaminergic Neurons

    Directory of Open Access Journals (Sweden)

    Collin J Lobb

    2011-05-01

    Full Text Available Substantia nigra pars compacta (SNpc dopaminergic neurons receive strong tonic inputs from GABAergic neurons in the substantia nigra pars reticulata (SNpr and globus pallidus (GP, and glutamatergic neurons in the subthalamic nucleus. The presence of these tonic inputs raises the possibility that phasic disinhibition may trigger phasic bursts in dopaminergic neurons. We first applied constant NMDA and GABAA conductances onto a two-compartment single cell model of the dopaminergic neuron (Kuznetsov et al., 2006. The model exhibited disinhibition bursting upon stepwise removal of inhibition. A further bifurcation analysis suggests that disinhibition may be more robust than excitation alone in that for most levels of NMDA conductance, the cell remains capable of bursting even after a complete removal of inhibition, whereas too much excitatory input will drive the cell into depolarization block. To investigate the network dynamics of disinhibition, we used a modified version of an integrate-and-fire based model of the basal ganglia (Humphries et al., 2006. Synaptic activity generated in the network was delivered to the two-compartment single cell dopaminergic neuron. Phasic activation of the D1-expressing medium spiny neurons in the striatum (D1STR produced disinhibition bursts in dopaminergic neurons through the direct pathway (D1STR to SNpr to SNpc. Anatomical studies have shown that D1STR neurons have collaterals that terminate in GP. Adding these collaterals to the model, we found that striatal activation increased the intra-burst firing frequency of the disinhibition burst as the weight of this connection was increased. Our studies suggest that striatal activation is a robust means by which disinhibition bursts can be generated by SNpc dopaminergic neurons, and that recruitment of the indirect pathway via collaterals may enhance disinhibition bursting.

  19. A Study of Bubble and Slug Gas-Liquid Flow in a Microgravity Environment

    Science.gov (United States)

    McQuillen, J.

    2000-01-01

    The influence of gravity on the two-phase flow dynamics is obvious.As the gravity level is reduced,there is a new balance between inertial and interfacial forces, altering the behavior of the flow. In bubbly flow,the absence of drift velocity leads to spherical-shaped bubbles with a rectilinear trajectory.Slug flow is a succession of long bubbles and liquid slug carrying a few bubbles. There is no flow reversal in the thin liquid film as the long bubble and liquid slug pass over the film. Although the flow structure seems to be simpler than in normal gravity conditions,the models developed for the prediction of flow behavior in normal gravity and extended to reduced gravity flow are unable to predict the flow behavior correctly.An additional benefit of conducting studies in microgravity flows is that these studies aide the development of understanding for normal gravity flow behavior by removing the effects of buoyancy on the shape of the interface and density driven shear flows between the gas and the liquid phases. The proposal calls to study specifically the following: 1) The dynamics of isolated bubbles in microgravity liquid flows will be analyzed: Both the dynamics of spherical isolated bubbles and their dispersion by turbulence, their interaction with the pipe wall,the behavior of the bubbles in accelerated or decelerated flows,and the dynamics of isolated cylindrical bubbles, their deformation in accelerated/decelerated flows (in converging or diverging channels), and bubble/bubble interaction. Experiments will consist of the use of Particle Image Velocimetry (PIV) and Laser Doppler Velocimeters (LDV) to study single spherical bubble and single and two cylindrical bubble behavior with respect to their influence on the turbulence of the surrounding liquid and on the wall 2) The dynamics of bubbly and slug flow in microgravity will be analyzed especially for the role of the coalescence in the transition from bubbly to slug flow (effect of fluid properties and

  20. Fermi/GBM Observations of SGRJ0501 + 4516 Bursts

    Science.gov (United States)

    Lin, Lin; Kouveliotou, Chryssa; Baring, Matthew G.; van der Horst, Alexander J.; Guiriec, Sylvain; Woods, Peter M.; Goegues, Ersin; Kaneko, Yuki; Scargle, Jeffrey; Granot, Jonathan; Preece, Robert; von Kienlin, Andreas; Chaplin, Vandiver; Watts, Anna L.; Wijers, Ralph A. M. J.; Zhang, Shuang Nan; Bhat, Narayan; Finger, Mark H.; Gehrels. Neil; Harding, Alice; Kaper, Lex; Kaspi, Victoria; Mcenery, Julie; Meegan, Charles A.; Wilson-Hodge, Colleen

    2011-01-01

    We present our temporal and spectral analyses of 29 bursts from SGRJ0501+4516, detected with the Gamma-ray Burst Monitor onboard the Fermi Gamma-ray Space Telescope during the 13 days of the source activation in 2008 (August 22 to September 3). We find that the T(sub 90) durations of the bursts can be fit with a log-normal distribution with a mean value of approx. 123 ms. We also estimate for the first time event durations of Soft Gamma Repeater (SGR) bursts in photon space (i.e., using their deconvolved spectra) and find that these are very similar to the T(sub 90)s estimated in count space (following a log-normal distribution with a mean value of approx. 124 ms). We fit the time-integrated spectra for each burst and the time-resolved spectra of the five brightest bursts with several models. We find that a single power law with an exponential cutoff model fits all 29 bursts well, while 18 of the events can also be fit with two black body functions. We expand on the physical interpretation of these two models and we compare their parameters and discuss their evolution. We show that the time-integrated and time-resolved spectra reveal that E(sub peak) decreases with energy flux (and fluence) to a minimum of approx. 30 keV at F = 8.7 x 10(exp -6)erg/sq cm/s, increasing steadily afterwards. Two more sources exhibit a similar trend: SGRs J1550 - 5418 and 1806 - 20. The isotropic luminosity, L(sub iso), corresponding to these flux values is roughly similar for all sources (0.4 - l.5 x 10(exp 40) erg/s.

  1. Activity from Magnetar Candidate 4U 0142+61: Bursts and Emission Lines

    CERN Document Server

    Gavriil, Fotis P; Kaspi, Victoria M

    2007-01-01

    After 6 years of quiescence, Anomalous X-ray Pulsar (AXP) 4U 0142+61 entered an active phase in 2006 March that lasted several months. During the active phase, several bursts were detected, and many aspects of the X-ray emission changed. We report on the discovery of six X-ray bursts, the first ever seen from this AXP in ~10 years of Rossi X-ray Timing Explorer (RXTE) monitoring. All the bursts occurred in the interval between 2006 April 6 and 2007 February 7. The bursts had the canonical fast rise slow decay profiles characteristic of SGR/AXP bursts. The burst durations ranged from 8-3x10^3 s as characterized by T90,these are very long durations even when compared to the broad T90 distributions of other bursts from SGRs and AXPs. The first five burst spectra are well modeled by simple blackbodies, with temperature kT ~2-6 keV. However, the sixth burst had a complicated spectrum consisting of at least three emission lines with possible additional emission and absorption lines. The most significant feature was...

  2. Swift-BAT: The First Year of Gamma-Ray Burst Detections

    Science.gov (United States)

    Krimm, Hans A.

    2006-01-01

    The Burst Alert Telescope (BAT) on the Swift has been detecting gamma-ray bursts (GRBs) since Dec. 17,2004 and automated burst alerts have been distributed since Feb. 14,2005. Since commissioning the BAT has triggered on more than 100 GRBs, nearly all of which have been followed up by the narrow-field instruments on Swift through automatic repointing, and by ground and other satellite telescopes after rapid notification. Within seconds of a trigger the BAT produces and relays to the ground a position good to three arc minutes and a four channel light curve. A full ten minutes of event data follows on subsequent ground station passes. The burst archive has allowed us to determine ensemble burst parameters such as fluence, peak flux and duration. An overview of the properties of BAT bursts and BAT'S performance as a burst monitor will be presented in this talk. BAT is a coded aperture imaging system with a wide (approx.2 sr) field of view consisting of a large coded mask located 1 m above a 5200 cm2 array of 32.768 CdZnTe detectors. All electronics and other hardware systems on the BAT have been operating well since commissioning and there is no sign of any degradation on orbit. The flight and ground software have proven similarly robust and allow the real time localization of all bursts and the rapid derivation of burst light curves, spectra and spectral fits on the ground.

  3. A mini slug test method for determination of a local hydraulic conductivity of an unconfined sandy aquifer

    DEFF Research Database (Denmark)

    Hinsby, Klaus; Bjerg, Poul Løgstrup; Andersen, Lars J.;

    1992-01-01

    A new and efficient mini slug test method for the determination of local hydraulic conductivities in unconfined sandy aquifers is developed. The slug test is performed in a small-diameter (1 inch) driven well with a 0.25 m screen just above the drive point. The screened drive point can be driven...... from level to level and thereby establish vertical profiles of the hydraulic conductivity. The head data from the test well are recorded with a 10 mm pressure transducer, and the initial head difference required is established by a small vacuum pump. The method described has provided 274 spatially...... distributed measurements of a local hydraulic conductivity at a tracer test site at Vejen, Denmark. The mini slug test results calculated by a modified Dax slug test analysing method, applying the elastic storativity in the Dax equations instead of the specific yield, are in good accordance with the results...

  4. Testing for Nonlinearity in Dynamic Characteristics of Vertical Upward Oil-Gas-Water Three-phase Bubble and Slug Flows

    Institute of Scientific and Technical Information of China (English)

    朱雷; 金宁德; 高忠科; 杜萌; 王振亚

    2012-01-01

    Based on the conductance fluctuation signals measured from vertical upward oil-gas-water three-phase flow experiment, time frequency representation and surrogate data method were used to investigate dynamical characteristics of oil-in-water type bubble and slug flows. The results indicate that oil-in-water type bubble flow will turn to deterministic motion with the increase of oil phase fraction f o and superficial gas velocity U sg under fixed flowrate of oil-water mixture Q mix . The dynamics of oil-in-water type slug flow becomes more complex with the increase of U sg under fixed flowrate of oil-water mixture. The change of f o leads to irregular influence on the dynamics of slug flow. These interesting findings suggest that the surrogate data method can be a faithful tool for characterizing dynamic characteristics of oil-in-water type bubble and slug flows.

  5. Broadband Spectral Investigations of SGR J1550-5418 Bursts

    CERN Document Server

    Lin, Lin; Baring, Matthew G; Granot, Jonathan; Kouveliotou, Chryssa; Kaneko, Yuki; van der Horst, Alexander; Gruber, David; von Kienlin, Andreas; Younes, George; Watts, Anna L; Gehrels, Neil

    2012-01-01

    We present the results of our broadband spectral analysis of 42 SGR J1550-5418 bursts simultaneously detected with the Swift/X-ray Telescope (XRT) and the Fermi/Gamma-ray Burst Monitor (GBM), during the 2009 January active episode of the source. The unique spectral and temporal capabilities of the XRT Windowed Timing mode have allowed us to extend the GBM spectral coverage for these events down to the X-ray domain (0.5-10 keV). Our earlier analysis of the GBM data found that the SGR J1550-5418 burst spectra were described equally well with a Comptonized model or with two blackbody functions; the two models were statistically indistinguishable. Our new broadband (0.5 - 200 keV) spectral fits show that, on average, the burst spectra are better described with two blackbody functions than with the Comptonized model. Thus, our joint XRT/GBM analysis clearly shows for the first time that the SGR J1550-5418 burst spectra might naturally be expected to exhibit a more truly thermalized character, such as a two-blackbo...

  6. Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition.

    Directory of Open Access Journals (Sweden)

    Guanxiong Ding

    Full Text Available Though prostate cancer (PCa has slow progression, the hormone refractory (HRCP and metastatic entities are substantially lethal and lack effective treatments. Transcription factor Slug is critical in regulating metastases of various tumors including PCa. Here we studied targeted therapy against Slug using combination of 3 drugs targeting 3 pathways respectively converging via Slug and further regulating PCa metastasis. Using in vitro assays we confirmed that Slug up-regulation incurred inhibition of E-cadherin that was anti-metastatic, and inhibited Bim-regulated cell apoptosis in PCa. Upstream PTEN/Akt, mTOR, Erk, and AR/Hsp90 pathways were responsible for Slug up-regulation and each of these could be targeted by rapamycin, CI-1040, and 17-AAG respectively. In 4 PCa cell lines with different traits in terms of PTEN loss and androgen sensitivity we tested the efficacy of mono- and combined therapy with the drugs. We found that metastatic capacity of the cells was maximally inhibited only when all 3 drugs were combined, due to the crosstalk between the pathways. 17-AAG decreases Slug expression via blockade of HSP90-dependent AR stability. Combination of rapamycin and CI-1040 diminishes invasiveness more potently in PCa cells that are androgen insensitive and with PTEN loss. Slug inhibited Bim-mediated apoptosis that could be rescued by mTOR/Erk/HSP90 inhibitors. Using mouse models for circulating PCa DNA quantification, we found that combination of mTOR/Erk/HSP90 inhibitors reduced circulating PCa cells in vivo significantly more potently than combination of 2 or monotherapy. Conclusively, combination of mTOR/Erk/Hsp90 inhibits metastatic capacity of prostate cancer via Slug inhibition.

  7. Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity

    Directory of Open Access Journals (Sweden)

    Giovanna Ferrari-Amorotti

    2014-12-01

    Full Text Available Most triple-negative breast cancers (TNBCs exhibit gene expression patterns associated with epithelial-to-mesenchymal transition (EMT, a feature that correlates with a propensity for metastatic spread. Overexpression of the EMT regulator Slug is detected in basal and mesenchymal-type TNBCs and is associated with reduced E-cadherin expression and aggressive disease. The effects of Slug depend, in part, on the interaction of its N-terminal SNAG repressor domain with the chromatin-modifying protein lysine demethylase 1 (LSD1; thus, we investigated whether tranylcypromine [also known as trans-2-phenylcyclopropylamine hydrochloride (PCPA or Parnate], an inhibitor of LSD1 that blocks its interaction with Slug, suppresses the migration, invasion, and metastatic spread of TNBC cell lines. We show here that PCPA treatment induces the expression of E-cadherin and other epithelial markers and markedly suppresses migration and invasion of TNBC cell lines MDA-MB-231 and BT-549. These effects were phenocopied by Slug or LSD1 silencing. In two models of orthotopic breast cancer, PCPA treatment reduced local tumor growth and the number of lung metastases. In mice injected directly in the blood circulation with MDA-MB-231 cells, PCPA treatment or Slug silencing markedly inhibited bone metastases but had no effect on lung infiltration. Thus, blocking Slug activity may suppress the metastatic spread of TNBC and, perhaps, specifically inhibit homing/colonization to the bone.

  8. INFLUENCE OF INCLINATION ANGLE ON THE MOTION OF TAYLOR BUBBLES IN UPWARD SLUG FLOW

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The motion of the Taylor bubbles in vertical and near-vertical tubes was investigated. The non-invasive measurements were conducted by using a high-speed motion analyzer. For the vertical slug flow, the coefficient C1 was found to be very close to the ratio of the maximum velocity to the average velocity in the profile. For the inclined slug flow, the value of C1 is smaller than that for the vbertical case because the nose tip of the Taylor bubble usually deviates from the centerline. The drift velocity is increased with the decrease of inclination angle. Based on the theoretical analysis and experimental data, the bubble velocity correlations were obtained. The results are in good agreement with the available data.

  9. Antifeedant compounds from three species of Apiaceae active against the field slug, Deroceras reticulatum (Muller).

    Science.gov (United States)

    Birkett, Michael A; Dodds, Catherine J; Henderson, Ian F; Leake, Lucy D; Pickett, John A; Selby, Martin J; Watson, Peter

    2004-03-01

    Extracts of volatiles from foliage of three plants in the Apiaceae, Conium maculatum L. (hemlock), Coriandrum sativum L. (coriander), and Petroselinum crispum Mill. (Nym.) (parsley), previously shown to exhibit antifeedant activity in assays with the field slug, Deroceras reticulatum (Muller) (Limacidae: Pulmonata), were studied further to identify the active components. Coupled gas chromatography-mass spectrometry (GC-MS) and neurophysiological assays using tentacle nerve preparations resulted in the identification of 11 active compounds from the three extracts. Wheat flour feeding bioassays were used to determine which of these compounds had the highest antifeedant activity. One of the most active compounds was the alkaloid gamma-coniceine, from C. maculatum. The role of potentially toxic alkaloids as semiochemicals and the potential for using such compounds as crop protection agents to prevent slug feeding damage is discussed. PMID:15139308

  10. Slug Test in a Large Dip Angle Fracture Zone: Model and Field Experiment

    Directory of Open Access Journals (Sweden)

    Ying Liu and Chia-Shyun Chen

    2015-01-01

    Full Text Available A single-porosity model is developed to deal with a fracture zone slug test in a large dip angle by assuming the fracture zone causes a downward regional flow. For the oscillatory response, a larger dip angle causes larger amplitude while introduces little impact on period. The effective water length, an important parameter necessary for analyzing the oscillatory response, is proven to be independent of the dip angle and can be evaluated using the available horizontal formation methods. The dip angle effect is more pronounced for a larger storage coefficient. An empirical relationship is developed to evaluate the limiting dip angle, below which the dip angle effect is negligible. Field data analysis of a slug test in a _ dip angle fracture zone indicates that neglecting the dip angle can result in a 27% transmissivity over estimation and a 53% storage coefficient under estimation.

  11. A criterion for the onset of slugging in horizontal stratified air-water countercurrent flow

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Moon-Hyun; Lee, Byung-Ryung; Kim, Yang-Seok [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)] [and others

    1995-09-01

    This paper presents an experimental and theoretical investigation of wave height and transition criterion from wavy to slug flow in horizontal air-water countercurrent stratified flow conditions. A theoretical formula for the wave height in a stratified wavy flow regime has been developed using the concept of total energy balance over a wave crest to consider the shear stress acting on the interface of two fluids. From the limiting condition of the formula for the wave height, a necessary criterion for transition from a stratified wavy flow to a slug flow has been derived. A series of experiments have been conducted changing the non-dimensional water depth and the flow rates of air in a horizontal pipe and a duct. Comparisons between the measured data and the predictions of the present theory show that the agreement is within {plus_minus}8%.

  12. Broadband Spectral Study of Magnetar Bursts

    Science.gov (United States)

    Kirmizibayrak, Demet; Gogus, Ersin; Sasmaz Mus, Sinem; Kaneko, Yuki

    2016-07-01

    Magnetar bursts occur sporadically on random occasions, and every burst-active episode carries unique information about the bursting magnetar. Therefore, in-depth spectral and temporal analyses of each of the magnetar bursts provide new insights into the bursting and radiation mechanisms. There have been a number of studies over the last decade, investigating the spectral and temporal properties of magnetar bursts. The spectra of typical magnetar bursts were generally described with the Comptonized model or the sum of two blackbody functions. However, it was recently shown that the actual spectral nature of these bursts can be conclusively determined if the spectral analysis is performed on a wide energy coverage. We present the results of in-depth systematic broadband (2 - 250 keV) spectral analysis of a large number of bursts originated from three magnetars: SGR 1806-20, SGR 1900+14, and SGR J1550-5418, observed with the Rossi X-ray Timing Explorer.

  13. Slug-annular transition with particular reference to narrow rectangular ducts

    International Nuclear Information System (INIS)

    The transition from slug-flow to annular-flow in two-phase, gas-liquid mixtures is analyzed. A transition equation is derived which agrees well when compared with objective data determined from the disappearance of the low-void peak in the void fluctuation probability density in a rectangular duct. Application to other geometries is suggested and tabular recommendations given for determination of the drift flux coefficient, K, based on results in the literature

  14. Slug initiation and prediction using high accuracy methods - applications with field data

    OpenAIRE

    Kalogerakos, Stamatis

    2011-01-01

    The sponsoring company of the project is BP. The framework within which the research is placed is that of the Transient Multiphase Flow Programme (TMF-4), a consortium of companies that are interested in phenomena related to flow of liquids and gases, in particular with relevance to oil, water and air. The deliverables agreed for the project were: • validating EMAPS through simulations of known problems and experimental and field data concerning slug flow • introducing numer...

  15. Flow near the meniscus of a pressure-driven water slug in microchannels

    International Nuclear Information System (INIS)

    Micro-PIV system with a high speed CCD camera is used to measure the flow field near the advancing meniscus of a water slug in microchannels. Image shifting technique combined with meniscus detecting technique is proposed to measure the relative velocity of the liquid near the meniscus in a moving reference frame. The proposed method is applied to an advancing front of a slug in microchannels with rectangular cross section. In the case of hydrophilic channel, strong flow from the center to the side wall along the meniscus occurs, while in the case of the hydrophobic channel, the fluid flows in the opposite direction. Further, the velocity near the side wall is higher than the center region velocity, exhibiting the characteristics of a strong shear-driven flow. This phenomenon is explained to be due to the existence of small gaps between the slug and the channel wall at each capillary corner so that the gas flows through the gaps inducing high shear on the slug surface. Simulation of the shape of a static droplet inside a cubic cell obtained by using the Surface Evolver program is supportive of the existence of the gap at the rectangular capillary corners. The flow fields in the circular capillary, in which no such gap exists, are also measured. The results show that a similar flow pattern to that of the hydrophilic rectangular capillary (i.e., center-to-wall flow) is always exhibited regardless of the wettability of the channel wall, which is also indicative of the validity of the above-mentioned assertion

  16. CFD modelling of liquid–liquid multiphase microstructured reactor: Slug flow generation

    OpenAIRE

    Kashid, Madhvanand Namadeo; Renken, Albert; Kiwi-Minsker, Lioubov

    2010-01-01

    Microreactor technology, an important method of process intensification, offers numerous potential benefits for the process industries. Fluid–fluid reactions with mass transfer limitations have already been advantageously carried out in small-scale geometries. In liquid–liquid microstructured reactors (MSR), alternating uniform slugs of the twophase reaction mixture exhibit well-defined interfacial mass transfer areas and flow patterns. The improved control of highly exothermic and hazardous ...

  17. Experimental and modelling studies on liquid-liquid slug flow capillary microreactors

    OpenAIRE

    Kashid, Madhvanand N.

    2008-01-01

    Microreactor technology, an important method of process intensification, offers potential benefits to the chemical process industries due to the well-defined high specific interfacial area available for heat and mass transfer, which increases transfer rates, and enhances safety resulting from low hold-ups. The liquid-liquid slug flow capillary microreactor intensifies the mass transfer in biphasic systems through internal circulation caused by the shear between continuous phase/wall surface a...

  18. A field proof-of-concept of tomographic slug tests in an anisotropic littoral aquifer

    Science.gov (United States)

    Paradis, Daniel; Gloaguen, Erwan; Lefebvre, René; Giroux, Bernard

    2016-05-01

    Hydraulic tomography is increasingly recognized as a characterization approach that can image pathways or barriers to flow as well as their connectivity. In this study, we assess the performance of a transient analysis of tomographic slug test head data in estimating heterogeneity in horizontal hydraulic conductivity (Kh), hydraulic conductivity anisotropy (the ratio between vertical and horizontal hydraulic conductivity - Kv/Kh) and specific storage (Ss) under actual field conditions. The tomographic experiment was carried out between two wells in a moderately heterogeneous and highly anisotropic silt and sand littoral aquifer. In this field proof-of-concept, the inversion of the two-dimensional (2D) head dataset was computed with a 2D radial flow algorithm that considers Kh, Kv/Kh, Ss and wellbore storage effects. This study demonstrated that a transient analysis of tomographic slug tests is able to capture the key features of the littoral environment of the test: the vertical profiles of Kh and Kv are indeed in agreement with those from other field and laboratory tests, and Ss values exhibit physically plausible profiles. Furthermore, the simulation of independent inter-well hydraulic tests (slug and pumping tests screened over the entire aquifer) using resolved Kh, Kv/Kh and Ss tomograms produce responses very close to field observations. This study demonstrates that the effects of fine scale heterogeneity that induces K-anisotropy at larger scales can be captured through a transient analysis of tomographic slug tests, which are very difficult to quantify otherwise with conventional hydraulic tests, thus allowing a better representation of properties controlling flow and transport in aquifer systems.

  19. Liquid-liquid Slug Flow in a Microchannel Reactor and its Mass Transfer Properties - A Review

    Directory of Open Access Journals (Sweden)

    Rahul Antony

    2014-10-01

    Full Text Available Mass transfer is a basic phenomenon behind many processes like reaction, absorption, extraction etc. Mass transfer plays a significant role in microfluidic systems where the chemical / biological process systems are shrinkened down to a micro scale. Micro reactor system, with its high compatibility and performance, gains a wide interest among the researchers in the recent years. Micro structured reac-tors holds advantages over the conventional types in chemical processes. The significance of micro re-actor not limited to its scalability but to energy efficiency, on-site / on-demand production, reliability, safety, highly controlled outputs, etc. Liquid-liquid two phase reaction in a microreactor system is highly demandable when both reactants are liquids or when air medium cannot be suitable. This arti-cle overviews various liquid-liquid flow regimes in a microchannel. Discussions on the hydrodynamics of flow in micro scale are made. Considering the importance of mass transfer in liquid-liquid systems and the advantage of slug regime over other regimes, the article focuses especially on the mass trans-fer between two liquid phases in slug flow and the details of experimental studies carried out in this area. The advantages of slug flow over other flow regimes in micro structured reactor applications are showcased. © 2014 BCREC UNDIP. All rights reservedReceived: 31st May 2014; Revised: 6th August 2014; Accepted: 14th August 2014How to Cite: Antony, R., Giri Nandagopal, M.S., Sreekumar, N., Rangabhashiyam, S., Selvaraju, N. (2014. Liquid-liquid Slug Flow in a Microchannel Reactor and its Mass Transfer Properties - A Review. Bulletin of Chemical Reaction Engineering & Catalysis,9(3: 207-223. (doi:10.9767/bcrec.9.3.6977.207-223Permalink/DOI: http://dx.doi.org/10.9767/bcrec.9.3.6977.207-223

  20. Numerical simulation of slug flow regime for an air water two-phase flow in horizontal pipes

    International Nuclear Information System (INIS)

    Slug flow is a quite common multiphase flow regime in horizontal pipelines and channels, which can be potentially hazardous to the structure of the pipe system or to apparatus and processes following the slug flow pipe section due to the strong oscillating pressure levels formed behind liquid slugs. Areas of application are in the chemical and process industry as well as in safety research and thermo-hydraulic engineering for nuclear power plants. The intended paper deals with the feasibility and accuracy of CFD simulations for an air-water slug flow in a horizontal circular pipe of diameter D = 0.054 m and a pipe length of up to 8 m. In the past most investigations of the slug flow regime in horizontal pipelines and channels have been carried out on experimental test rigs. Due to the transient and three-dimensional character of slug flow regime and the resulting numerical effort only a few attempts of numerical simulation have been made. In principal three different computational approaches can be applied for the simulation of horizontal slug flows: - 'frozen slug' in a domain with moving wall boundaries, where the absolute value of the prescribed wall velocity is equal to the slug propagation velocity in the pipe. The slug propagation velocity and the slug length/period has to be known in advance. - Transient 3-D simulation in a short computational domain with periodic boundary conditions. A driving pressure force has to be prescribed to compensate the kinetic energy losses due to wall friction. Furthermore it has to be ensured, that the geometrical dimensions of the computational domain do not affect the computed slug flow length and time scales. - Transient 3. simulation of slug flow in a long pipe segment with inlet/outlet boundary conditions. The later of the three computational approaches provides the highest predictive capability, also it is the most computational intensive approach. The presented paper will discuss the general aspects of feasibility

  1. Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma.

    Science.gov (United States)

    Lee, Hsin-Jung; Jeng, Yung-Ming; Chen, Yu-Ling; Chung, Ling; Yuan, Ray-Hwang

    2014-04-01

    Hepatocellular carcinoma (HCC) is one of the most common fatal cancers worldwide. Other than the sorafenib treatment, no effective systemic therapy has been available thus far. Most targets in molecularly targeted therapy for cancer are receptor tyrosine kinases (RTKs). Therefore, identifying activated RTKs in HCC is critical for developing new molecularly targeted therapies. Using a phospho-RTK array, we found that Axl is one of the most frequently activated RTKs in liver cancer cell lines. The knockdown of Axl by RNA interference significantly reduced cell migration and invasion in the HCC cell lines HA22T and Mahlavu. Stimulation of HCC cell lines by Axl ligand growth arrest-specific 6 (Gas6) enhanced cell migration and invasion. The Gas6/Axl pathway enhanced the expression of the epithelial-mesenchymal transition-inducing transcription factor Slug, which is essential for the invasion-promoting activity of Axl. Treating HCC cells with the Axl inhibitor bosutinib suppressed Slug expression and decreased the invasiveness of HCC cell lines. These findings indicate that Gas6/Axl regulates tumor invasion through the transcriptional activation of Slug.

  2. Interfacial area, velocity and void fraction in two-phase slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Kojasoy, G. [Univ. of Wisconsin, Milwaukee, WI (United States); Riznic, J.R. [Atomic Energy Control Board, Ottawa (Canada)

    1997-12-31

    The internal flow structure of air-water plug/slug flow in a 50.3 mm dia transparent pipeline has been experimentally investigated by using a four-sensor resistivity probe. Liquid and gas volumetric superficial velocities ranged from 0.55 to 2.20 m/s and 0.27 to 2.20 m/s, respectively, and area-averaged void fractions ranged from about 10 to 70%. The local distributions of void fractions, interfacial area concentration and interface velocity were measured. Contributions from small spherical bubbles and large elongated slug bubbles toward the total void fraction and interfacial area concentration were differentiated. It was observed that the small bubble void contribution to the overall void fraction was small indicating that the large slug bubble void fraction was a dominant factor in determining the total void fraction. However, the small bubble interfacial area contribution was significant in the lower and upper portions of the pipe cross sections.

  3. Investigation of redshift- and duration-dependent clustering of gamma-ray bursts

    Science.gov (United States)

    Ukwatta, T. N.; Woźniak, P. R.

    2016-01-01

    Gamma-ray bursts (GRBs) are detectable out to very large distances and as such are potentially powerful cosmological probes. Historically, the angular distribution of GRBs provided important information about their origin and physical properties. As a general population, GRBs are distributed isotropically across the sky. However, there are published reports that once binned by duration or redshift, GRBs display significant clustering. We have studied the redshift- and duration-dependent clustering of GRBs using proximity measures and kernel density estimation. Utilizing bursts detected by Burst and Transient Source Experiment, Fermi/gamma-ray burst monitor, and Swift/Burst Alert Telescope, we found marginal evidence for clustering in very short duration GRBs lasting less than 100 ms. Our analysis provides little evidence for significant redshift-dependent clustering of GRBs.

  4. GRANAT/WATCH catalogue of cosmic gamma-ray bursts: December 1989 to September 1994

    DEFF Research Database (Denmark)

    Sazonov, S.Y.; Sunyaev, R.A.; Terekhov, O.V.;

    1998-01-01

    We present the catalogue of gamma-ray bursts (GRB) observed with the WATCH all-sky monitor on board the GRANAT satellite during the period December 1989 to September 1994. The cosmic origin of 95 bursts comprising the catalogue is confirmed either bg their localization with WATCH...... or by their detection with other GRB experiments. For each burst its time history and information on its intensity in the two energy ranges 8-20 keV and 30-60 keV are presented, Most events show hardening of the energy spectrum near the burst peak. In part of the bursts an X-ray precursor or a tail is seen at 8-20 ke...

  5. Bursts in intermittent aeolian saltation

    CERN Document Server

    Carneiro, M V; Herrmann, H J

    2014-01-01

    Close to the onset of Aeolian particle transport through saltation we find in wind tunnel experiments a regime of intermittent flux characterized by bursts of activity. Scaling laws are observed in the time delay between each burst and in the measurements of the wind fluctuations at the critical Shields number $\\theta_c$. The time delay between each burst decreases on average with the increase of the Shields number until saltation becomes non-intermittent and the sand flux becomes continuous. A numerical model for saltation including the wind-entrainment from the turbulent fluctuations can reproduce these observations and gives insight about their origin. We present here also for the first time measurements showing that with feeding it becomes possible to sustain intermittent flux even below the threshold $\\theta_c$ for natural saltation initiation.

  6. Chimera states in bursting neurons

    Science.gov (United States)

    Bera, Bidesh K.; Ghosh, Dibakar; Lakshmanan, M.

    2016-01-01

    We study the existence of chimera states in pulse-coupled networks of bursting Hindmarsh-Rose neurons with nonlocal, global, and local (nearest neighbor) couplings. Through a linear stability analysis, we discuss the behavior of the stability function in the incoherent (i.e., disorder), coherent, chimera, and multichimera states. Surprisingly, we find that chimera and multichimera states occur even using local nearest neighbor interaction in a network of identical bursting neurons alone. This is in contrast with the existence of chimera states in populations of nonlocally or globally coupled oscillators. A chemical synaptic coupling function is used which plays a key role in the emergence of chimera states in bursting neurons. The existence of chimera, multichimera, coherent, and disordered states is confirmed by means of the recently introduced statistical measures and mean phase velocity.

  7. Modeling gamma-ray bursts

    Science.gov (United States)

    Maxham, Amanda

    central engine activity and compare the model results with the observational data. We show that the observed X-ray flare phenomenology can be explained within the internal shock model. The number, width and occurring time of flares are then used to diagnose the central engine activity, putting constraints on the energy, ejection time, width and number of ejected shells. We find that the observed X-ray flare time history generally reflects the time history of the central engine, which reactivates multiple times after the prompt emission phase with progressively reduced energy. This shell model code can be used to constrain broadband observations of GRB 090926A, which showed two flares in both the Swift UVOT and XRT bands. Using the prompt emission fluence to constrain the total energy contained in the blastwave, the internal shock model requires that Lorentz factors of the shells causing flares must be less than the Lorentz factor of the blastwave when the shells are ejected. Recent observations of Gamma-Ray Bursts (GRBs) by the Fermi Large Area Telescope (LAT) revealed a power law decay feature of the high energy emission (above 100 MeV), which led to the suggestion that it originates from an external shock. We analyze four GRBs (080916C, 090510, 090902B and 090926A) jointly detected by Fermi LAT and Gamma-ray Burst Monitor (GBM), which have high quality lightcurves in both instrument energy bands. Using the MeV prompt emission (GBM) data, we can record the energy output from the central engine as a function of time. Assuming a constant radiative efficiency, we are able to track energy accumulation in the external shock using our internal/external shell model code and show that the late time lightcurves fit well within the external shock model, but the early time lightcurves are dominated by the internal shock component which has a shallow decay phase due to the initial pile-up of shells onto the blast wave.

  8. US Army Nuclear Burst Detection System (NBDS)

    International Nuclear Information System (INIS)

    The Nuclear Burst Detection System (NBDS) was developed to meet the Army requirements of an unattended, automatic nuclear burst reporting system. It provides pertinent data for battlefield commanders on a timely basis with high reliability

  9. Slug length evolution of gas-liquid slug flow in combined riser pipe with small length-diameter ratio%小长径比组合立管内液塞长度演化规律

    Institute of Scientific and Technical Information of China (English)

    王立满; 何利民; 罗小明

    2015-01-01

    The evolution of slug length distribution was investigated in a combined riser pipe, which is the pipe in front of the inlet of gas-liquid cylindrical cyclone separator ( GLCC) with small length-diameter ratio. It is found that the slug velocity decreases as the slug flows from horizontal inlet to vertical section and increases as it passes through the vertical section. This phenomenon affects the calculation of slug length. The slug length distributions of the inlet, vertical pipe and outlet all con-form to log-normal distribution. With the increase of gas superficial velocity, the mean slug length of the inlet section firstly increases then decreases, and the mean slug length of outlet section decreases. With the increase of gas superficial velocity, the mean slug length of the vertical section decreases at low liquid superficial velocity, and firstly increases then decreases at high liquid superficial velocity. The mean slug length firstly increases then decreases from inlet to outlet of the combined riser pipe.%以气液柱状旋流分离器( GLCC)入口管之前的小长径比组合立管为对象,建立一套气液两相流试验系统,实验研究组合立管内不同位置的液塞长度统计分布规律。结果表明:液塞从水平入口段进入立管段直至排出的过程中存在液塞减速与加速现象,计算液塞长度时必须考虑。水平入口段、立管段及水平出口段的液塞长度分布均符合对数正态分布;随折算气速增大,入口段平均液塞长度先增大后减小,出口段平均液塞长度则呈减小趋势。在低折算液速下,立管段平均液塞长度随折算气速增大而减小;高折算液速时,平均液塞长度随折算气速增大先增大后减小。液塞通过整个组合立管的过程中,平均液塞长度先增大后减小。

  10. Millisecond extragalactic radio bursts as magnetar flares

    CERN Document Server

    Popov, S B

    2013-01-01

    Properties of the population of millisecond extragalactic radio bursts discovered by Thornton et al. (2013) are in good correspondence with the hypothesis that such events are related to hyperflares of magnetars, as was proposed by us after the first observation of an extragalactic millisecond radio burst by Lorimer et al. (2007). We also point that some of multiple millisecond radio bursts from M31 discovered by Rubio-Herrera et al. (2013) also can be related to weaker magnetar bursts.

  11. The Fermi-GBM 3-year X-ray Burst Catalog

    CERN Document Server

    Jenke, P A; Connaughton, V; Beklen, E; Camero-Arranz, A; Finger, M H; Wilson-Hodge, C A

    2016-01-01

    The Fermi Gamma Ray Burst Monitor (GBM) is an all sky gamma-ray monitor well known in the gamma-ray burst community. Although GBM excels in detecting the hard, bright extragalactic GRBs, its sensitivity above 8 keV and all-sky view make it an excellent instrument for the detection of rare, short-lived Galactic transients. In March 2010, we initiated a systematic search for transients using GBM data. We conclude this phase of the search by presenting a 3 year catalog of 1084 non-solar events. Using spectral analysis, location and spatial distributions we subdivided the 1084 events into 752 thermonuclear X-ray bursts, 267 transient events from accretion flares and X-ray pulses, and 65 untriggered gamma-ray bursts.

  12. Long Type I X-ray Bursts and Neutron Star Interior Physics

    OpenAIRE

    Cumming, Andrew; Macbeth, Jared; Zand, J. J. M. in't; Page, Dany

    2005-01-01

    Superbursts are very energetic Type I X-ray bursts discovered in recent years by long term monitoring of X-ray bursters, believed to be due to unstable ignition of carbon in the deep ocean of the neutron star. A number of "intermediate duration" bursts have also been observed, probably associated with ignition of a thick helium layer. We investigate the sensitivity of these long X-ray bursts to the thermal profile of the neutron star crust and core. We first compare cooling models of superbur...

  13. MULTIPHASE DROPLET/SLUG BREAK-UP MECHANISM IN MICROFLUIDIC T-JUNCTIONS AT VARIOUS WEBER NUMBERS

    Directory of Open Access Journals (Sweden)

    Wan Leng (Dawn Leow

    2011-10-01

    Full Text Available Normal 0 false false false EN-MY X-NONE X-NONE The formation of immiscible liquid droplets, or slugs, in microchannels features the advantages of volume control and mixing enhancement over single-phase microflows. Although the applications of droplet-based microfluidics have been widely demonstrated, the fundamental physics governing droplet break-up remains an area of active research. This study defines an effective Weber (Weeff number that characterizes the interplay of interfacial tension, shear stress and channel pressure drop in driving slug formation in T-junction microchannel for a relative range of low, intermediate and high flow rates. The immiscible fluid system in this study consists of Tetradecane slug formation in Acetonitrile. The progressive deformation of slug interfaces during break-up events is observed. Experimental results indicate that, at a relatively low Weeff, clean slug break-up occurs at the intersection of the side and main channels. At intermediate Weeff, the connecting neck of the dispersed phase is stretched to a short and thin trail of laminar flow prior to breaking up a short distance downstream of the T-junction. At a relatively high Weeff, the connecting neck develops into a longer and thicker trail of laminar flow that breaks up further downstream of the main channel.

  14. Off-take and slug transition at T-junction of vertical-up branch in the horizontal pipe

    International Nuclear Information System (INIS)

    The off-take and the slug transition on air-water interface are experimentally investigated at the T-junction of the horizontal pipe with a vertical upward branch to simulate the loss-of-residual-heat-removal during a mid-loop operation in the Korea standard nuclear power plant. Scaling analysis is performed to scale down the experimental facility to the reference nuclear power plant. Two different diameters of branch pipes are used to verify the scaling laws and their scale effects. Air is used as working gaseous fluid and no water flow exists. Off-take behavior on horizontal stratified and slug flows is visually observed in the horizontal pipe. The experimental data are divided into three categories; onset of liquid entrainment at T-junctions, onset of slug transition in the horizontal pipe, and discharge quality in the branch pipe. It is found out that the scale effect of the branch diameter on the onset of liquid entrainment is small and the existing correlations for it are applicable. Also, the onset of slug transition shows a discrepancy with Taitel-Dukler's correlation and has a strong influence on the discharge quality. New correlations for discharge quality are developed considering the critical dependency of the onset of slugging. (author)

  15. The distributed-order fractional diffusion-wave equation of groundwater flow: Theory and application to pumping and slug tests

    Science.gov (United States)

    Su, Ninghu; Nelson, Paul N.; Connor, Sarah

    2015-10-01

    We present a distributed-order fractional diffusion-wave equation (dofDWE) to describe radial groundwater flow to or from a well, and three sets of solutions of the dofDWE for flow from a well for aquifer tests: one for pumping tests, and two for slug tests. The dofDWE is featured by two temporal orders of fractional derivatives, β1 and β2, which characterise small and large pores, respectively. By fitting the approximate solutions of the dofDWE to data from slug tests in the field, we determined the effective saturated hydraulic conductivity, Ke, transmissivity, Tf, and the order of fractional derivatives, β2 in one test and β2 and β1 in the second test. We found that the patterns of groundwater flow from a well during the slug tests at this site belong to the class of sub-diffusion with β2 concept of the critical time to link Ke as a function of β2 and β1. The importance of the orders of fractional derivatives is obvious in the approximate solutions: for short time slug tests only the parameter β2 for flow in large pores is present while for long time slug tests the parameters β2 and β1 are present indicating both large and small pores are functioning.

  16. Palatability of weeds from different European origins to the slugs Deroceras reticulatum Müller and Arion lusitanicus Mabille

    Science.gov (United States)

    Keller, Michael; Kollmann, Johannes; Edwards, Peter J.

    1999-04-01

    As part of a study on the significance of seed provenances in schemes to enhance biodiversity in agricultural habitats, juvenile plants of Cichorium intybus, Daucus carota, Leucanthemum vulgare and Silene alba of different European origins were exposed to grazing by two slug species, Deroceras reticulatum and Arion lusitanicus. Living plants were offered in trays, either in a glasshouse ( Deroceras) or outdoors ( Arion). The amount of herbivory was origin-dependent, with higher losses for all four species from German and Hungarian provenances compared with English and Swiss plants. The main trend was similar for both slug species except in the case of Daucus, and there was a significant 'origin × plant species' interaction. We found strong correlations between provenance-specific herbivory and certain climatic characteristics of the corresponding regions, i.e. winter minimum temperatures, and dryness in spring and late summer, which are crucial for the development of slugs. The results can be interpreted in terms of a SW-NE European climatic gradient and may be a consequence of differences in the need for plant defences against herbivory by slugs. Additionally, the data on palatability were compared with susceptibility towards two parasites which occurred in a field experiment, a leaf miner on Leucanthemum vulgare and a rust fungus on Silene alba. While specific leaf mining frequencies on Leucanthemum contrasted with the palatability of the different provenances to slugs, the rust infection on Silene was low on local and German plants, and higher on the more distant provenances from England and Hungary.

  17. Maxi observations of long X-ray bursts

    CERN Document Server

    Serino, Motoko; Tamagawa, Toru; Sakamoto, Takanori; Nakahira, Satoshi; Matsuoka, Masaru; Yamaoka, Kazutaka; Negoro, Hitoshi

    2016-01-01

    We report nine long X-ray bursts from neutron stars, detected with Monitor of All-sky X-ray Image (MAXI). Some of these bursts lasted for hours, and hence are qualified as superbursts, which are prolonged thermonuclear flashes on neutron stars and are relatively rare events. MAXI observes roughly 85% of the whole sky every 92 minutes in the 2-20 keV energy band, and has detected nine bursts with a long e-folding decay time, ranging from 0.27 to 5.2 hours, since its launch in 2009 August until 2015 August. The majority of the nine events were found to originate from transient X-ray sources. The persistent luminosities of the sources, when these prolonged bursts were observed, were lower than 1% of the Eddington luminosity for five of them and lower than 20% for the rest. This trend is contrastive to the 18 superbursts observed before MAXI, all but two of which originated from bright persistent sources. The distribution of the total emitted energy, i.e., the product of e-folding time and luminosity, of these bu...

  18. Slugs' last meals: molecular identification of sequestered chloroplasts from different algal origins in Sacoglossa (Opisthobranchia, Gastropoda).

    Science.gov (United States)

    Händeler, Katharina; Wägele, Heike; Wahrmund, Ute; Rüdinger, Mareike; Knoop, Volker

    2010-11-01

    Some sacoglossan sea slugs have become famous for their unique capability to extract and incorporate functional chloroplasts from algal food organisms (mainly Ulvophyceae) into their gut cells. The functional incorporation of the so-called kleptoplasts allows the slugs to rely on photosynthetic products for weeks to months, enabling them to survive long periods of food shortage over most of their life-span. The algal food spectrum providing kleptoplasts as temporary, non-inherited endosymbionts appears to vary among sacoglossan slugs, but detailed knowledge is sketchy or unavailable. Accurate identification of algal donor species, which provide the chloroplasts for long-term retention is of primary importance to elucidate the biochemical mechanisms allowing long-term functionality of the captured chloroplast in the foreign animal cell environment. Whereas some sacoglossans forage on a variety of algal species, (e.g. Elysia crispata and E. viridis) others are more selective. Hence, characterizing the range of functional sacoglossan-chloroplast associations in nature is a prerequisite to understand the basis of this enigmatic endosymbiosis. Here, we present a suitable chloroplast gene (tufA) as a marker, which allows identification of the respective algal kleptoplast donor taxa by analysing DNA from whole animals. This novel approach allows identification of donor algae on genus or even species level, thus providing evidence for the taxonomic range of food organisms. We report molecular evidence that chloroplasts from different algal sources are simultaneously incorporated in some species of Elysia. NeigborNet analyses for species assignments are preferred over tree reconstruction methods because the former allow more reliable statements on species identification via barcoding, or rather visualize alternative allocations not to be seen in the latter. PMID:21565106

  19. Gamma-Ray Bursts: The End Game

    Science.gov (United States)

    Lamb, Don

    1997-11-01

    The nature of gamma-ray bursts has been one of the greatest unsolved mysteries in astrophysics for more than a quarter century. A major reason for this is that no definite counterparts to the bursts could be found at other wavelengths, despite intense efforts spanning more than two decades. Consequently, the study of gamma-ray bursts has been isolated from the rest of astronomy. Scientists studying them have had only the laws of physics and the bursts themselves to guide them in attempting to solve the burst mystery. All of this changed dramatically with the discovery earlier this year of fading X-ray and optical sources in the arcminute-sized positional error boxes of several gamma-ray bursts. For the first time, temporal, as well as spatial, coincidence could be used to associate these X-ray and optical sources with the gamma-ray bursts. As a result, the odds are great that the fading X-ray and optical sources are counterparts of the bursts, and that the study of gamma-ray bursts has finally been connected with the rest of astronomy. In this talk, we describe the dramatic new information about the nature of gamma-ray bursts that the X-ray, optical, and radio observations of the fading sources have provided, and emphasize the implications that this information has for the distance scale to the bursts.

  20. Spindle Bursts in Neonatal Rat Cerebral Cortex

    Directory of Open Access Journals (Sweden)

    Jenq-Wei Yang

    2016-01-01

    Full Text Available Spontaneous and sensory evoked spindle bursts represent a functional hallmark of the developing cerebral cortex in vitro and in vivo. They have been observed in various neocortical areas of numerous species, including newborn rodents and preterm human infants. Spindle bursts are generated in complex neocortical-subcortical circuits involving in many cases the participation of motor brain regions. Together with early gamma oscillations, spindle bursts synchronize the activity of a local neuronal network organized in a cortical column. Disturbances in spindle burst activity during corticogenesis may contribute to disorders in cortical architecture and in the activity-dependent control of programmed cell death. In this review we discuss (i the functional properties of spindle bursts, (ii the mechanisms underlying their generation, (iii the synchronous patterns and cortical networks associated with spindle bursts, and (iv the physiological and pathophysiological role of spindle bursts during early cortical development.

  1. Spindle Bursts in Neonatal Rat Cerebral Cortex.

    Science.gov (United States)

    Yang, Jenq-Wei; Reyes-Puerta, Vicente; Kilb, Werner; Luhmann, Heiko J

    2016-01-01

    Spontaneous and sensory evoked spindle bursts represent a functional hallmark of the developing cerebral cortex in vitro and in vivo. They have been observed in various neocortical areas of numerous species, including newborn rodents and preterm human infants. Spindle bursts are generated in complex neocortical-subcortical circuits involving in many cases the participation of motor brain regions. Together with early gamma oscillations, spindle bursts synchronize the activity of a local neuronal network organized in a cortical column. Disturbances in spindle burst activity during corticogenesis may contribute to disorders in cortical architecture and in the activity-dependent control of programmed cell death. In this review we discuss (i) the functional properties of spindle bursts, (ii) the mechanisms underlying their generation, (iii) the synchronous patterns and cortical networks associated with spindle bursts, and (iv) the physiological and pathophysiological role of spindle bursts during early cortical development.

  2. 2800 MHz Solar Radio Bursts: A Statistical Analysis of 40 years of Data

    Science.gov (United States)

    Balachandran, B.; Lanzerotti, L. J.; Gary, D. E.

    2001-12-01

    The daily values of solar flux and radio bursts at 2800 MHz (10.7 cm wavelength) are known to be closely related to various manifestations of solar activity. The flux values, which vary slowly with time, have long been used as indicators of solar activity. Also, the number of radio bursts shows a variation with the phase of the solar cycle. The close relationships between the 2800 MHz bursts, the associated flares and geophysical phenomena such as shortwave fadeouts have been studied extensively and were established as early as the 1960s. Therefore, a constant monitoring of the Sun at this frequency would enable us to forecast the terrestrial disturbances following the solar activity. Moreover, a detailed study based on past data would help understand solar activity phenomena as well as the origin of these burst events. In the present analysis, we are revisiting some of these points by carrying out an analysis of 40 year data of solar radio bursts with special emphasis on 2800 MHz bursts. A scatter plot of the intensity vs duration shows that the distribution is not completely random but is double--pronged. This result is consistent with earlier works (e.g., Covington, 1959). The two-pronged distribution suggests the existence of two distinct types of burst events: impulsive and gradual rise and fall. The mechanisms that cause the emission of the two types of bursts are also different: the former due to nonthermal processes and the latter due to thermal processes. Our present analysis shows that the intensity--duration plot has a significant variation with the phase of the solar cycle. In addition to this, we present the behaviour of risetime vs duration as well as the frequency distribution of peak flux of these events. The analysis has also been extended to high frequency (> 10 GHz) bursts and the behaviour is contrasted to that of 2800 MHz bursts.

  3. Implementation of a new bubbly-slug interphase drag model in RELAP5/MOD2

    International Nuclear Information System (INIS)

    The implementation of a new bubbly-slug interphase drag model in the RELAP5/MOD2 code is described. The model is based on the determination of an effective interphase drag coefficient from a set of best-estimate void fraction correlations covering the full range of geometries and flow conditions encountered in PWR safety analysis. Calculations are reported which show that the new model leads to a much better prediction of void fraction profile for low flows in rod bundles than the standard model. Further work is necessary to derive a model formulation which can be guaranteed to produce physical drag coefficients in all flow situations. (author)

  4. Drift flux model as approximation of two fluid model for two phase dispersed and slug flow in tube

    International Nuclear Information System (INIS)

    The analysis of one-dimensional schematizing for non-steady two-phase dispersed and slug flow in tube is presented. Quasi-static approximation, when inertia forces because of the accelerations of the phases may be neglected, is considered. Gas-liquid bubbly and slug vertical upward flows are analyzed. Non-trivial theoretical equations for slip velocity for these flows are derived. Juxtaposition of the derived equations for slip velocity with the famous Zuber-Findlay correlation as cross correlation coefficients is criticized. The generalization of non-steady drift flux Wallis theory taking into account influence of wall friction on the bubbly or slug flows for kinematical waves is considered

  5. The slug mucosal irritation (SMI) assay: development of a screening tool for the evaluation of ocular discomfort caused by shampoos.

    Science.gov (United States)

    Lenoir, Joke; Claerhout, Ilse; Kestelyn, Philippe; Klomp, Andre; Remon, Jean-Paul; Adriaens, Els

    2011-12-01

    In this research, the slug mucosal irritation (SMI) assay was applied to predict ocular discomfort caused by shampoos to investigate the correlation between responses in slugs and humans. Several SMI experiments and a human eye irritation test (HEIT) were performed with 1 artificial tear solution (ArtTear) and 5 shampoos (A-E; 5%-dilution). In the HEIT, evaluation was performed by participants and an ophthalmologist at several time points. Analyses reveal that (1) a significant positive association existed between immediate stinging reaction reported by the participants and the mean total mucus produced by the slugs (MTMP) (Spearman's Rank correlation=0.986, pSMI assay is a promising evaluation method for discomfort in the human eye. Screening prototype (eye) formulations with this assay allows formula optimization prior to a HEIT.

  6. A PHYSICAL MODEL FOR PREDICTING THE PRESSURE DROP OF GAS-LIQUID SLUG FLOW IN HORIZONTAL PIPES

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A comprehensive treatment of all sources of pressure drop within intermittent gas-liquid flow is presented. A slug unit is divided into three parts and the pressure gradient of each part is calculated separately. In the mixing zone the momentum theory is employed and the mixing process between the film and slug is simulated by a two-dimensional wall jet entering a large reservoir to calculate the mixing length. The boundary layer theory is utilized to calculate the pressure drop for the slug body and the momentum equation of the film zone is integrated to calculate the pressure drop for the film zone. The pressure drop predicted in present model is in good agreement with all the measurements.

  7. An Analytical-Numerical Model for Two-Phase Slug Flow through a Sudden Area Change in Microchannels

    Directory of Open Access Journals (Sweden)

    A. Mehdizadeh Momen

    2016-01-01

    Full Text Available In this paper, two new analytical models have been developed to calculate two-phase slug flow pressure drop in microchannels through a sudden contraction. Even though many studies have been reported on two-phase flow in microchannels, considerable discrepancies still exist, mainly due to the difficulties in experimental setup and measurements. Numerical simulations were performed to support the new analytical models and to explore in more detail the physics of the flow in microchannels with a sudden contraction. Both analytical and numerical results were compared to the available experimental data and other empirical correlations. Results show that models, which were developed based on the slug and semi-slug assumptions, agree well with experiments in microchannels. Moreover, in contrast to the previous empirical correlations which were tuned for a specific geometry, the new analytical models are capable of taking geometrical parameters as well as flow conditions into account.

  8. Drift flux model as approximation of two fluid model for two phase dispersed and slug flow in tube

    Energy Technology Data Exchange (ETDEWEB)

    Nigmatulin, R.I.

    1995-09-01

    The analysis of one-dimensional schematizing for non-steady two-phase dispersed and slug flow in tube is presented. Quasi-static approximation, when inertia forces because of the accelerations of the phases may be neglected, is considered. Gas-liquid bubbly and slug vertical upward flows are analyzed. Non-trivial theoretical equations for slip velocity for these flows are derived. Juxtaposition of the derived equations for slip velocity with the famous Zuber-Findlay correlation as cross correlation coefficients is criticized. The generalization of non-steady drift flux Wallis theory taking into account influence of wall friction on the bubbly or slug flows for kinematical waves is considered.

  9. Removal of Molluscicidal Bait Pellets by Earthworms and its Impact on Control of the Gray Field Slug, Derocerus reticulatum Mueller, in Western Oregon Grass Seed Fields

    Science.gov (United States)

    Slugs are common pests of grass seed fields in western Oregon and are currently controlled using bait pellets that often fail to give adequate protection. Here we demonstrate the loss of bait pellet products to earthworms and its adverse effects on controlling slugs. Three years of field and greenho...

  10. Integrated Proteomics and Genomics Analysis Reveals a Novel Mesenchymal to Epithelial Reverting Transition in Leiomyosarcoma through Regulation of Slug*

    Science.gov (United States)

    Yang, Jilong; Eddy, James A.; Pan, Yuan; Hategan, Andrea; Tabus, Ioan; Wang, Yingmei; Cogdell, David; Price, Nathan D.; Pollock, Raphael E.; Lazar, Alexander J. F.; Hunt, Kelly K.; Trent, Jonathan C.; Zhang, Wei

    2010-01-01

    Leiomyosarcoma is one of the most common mesenchymal tumors. Proteomics profiling analysis by reverse-phase protein lysate array surprisingly revealed that expression of the epithelial marker E-cadherin (encoded by CDH1) was significantly elevated in a subset of leiomyosarcomas. In contrast, E-cadherin was rarely expressed in the gastrointestinal stromal tumors, another major mesenchymal tumor type. We further sought to 1) validate this finding, 2) determine whether there is a mesenchymal to epithelial reverting transition (MErT) in leiomyosarcoma, and if so 3) elucidate the regulatory mechanism responsible for this MErT. Our data showed that the epithelial cell markers E-cadherin, epithelial membrane antigen, cytokeratin AE1/AE3, and pan-cytokeratin were often detected immunohistochemically in leiomyosarcoma tumor cells on tissue microarray. Interestingly, the E-cadherin protein expression was correlated with better survival in leiomyosarcoma patients. Whole genome microarray was used for transcriptomics analysis, and the epithelial gene expression signature was also associated with better survival. Bioinformatics analysis of transcriptome data showed an inverse correlation between E-cadherin and E-cadherin repressor Slug (SNAI2) expression in leiomyosarcoma, and this inverse correlation was validated on tissue microarray by immunohistochemical staining of E-cadherin and Slug. Knockdown of Slug expression in SK-LMS-1 leiomyosarcoma cells by siRNA significantly increased E-cadherin; decreased the mesenchymal markers vimentin and N-cadherin (encoded by CDH2); and significantly decreased cell proliferation, invasion, and migration. An increase in Slug expression by pCMV6-XL5-Slug transfection decreased E-cadherin and increased vimentin and N-cadherin. Thus, MErT, which is mediated through regulation of Slug, is a clinically significant phenotype in leiomyosarcoma. PMID:20651304

  11. Analysis of Slug Flow in Multiphase Subsea Pipeline%混输管线段塞流分析

    Institute of Scientific and Technical Information of China (English)

    鞠朋朋; 秦家钧; 刘培林

    2012-01-01

    段塞流是混输管线流动保障中遇到的最严重问题之一.随着水深加大,其严重性也随之增加,影响到下游工艺设备的正常操作,甚至引起生产关断,因而在制定油气田前期开发方案时须要统筹考虑.分析了段塞流的产生机理,并分项阐明生产段塞、地形段塞和清管段塞等管线的段塞流情况,以及为降低段塞流对生产设备的影响而采取的措施.根据南海某项目具体情况,利用OLGA软件进行分析,对各种工况下的段塞流提出了解决方案.%Slug flow is a severe problem for multiphase subsea pipeline flow assurance, and becomes more import with the increase of water depth. It can result in unsmooth operation of process equipment, and serious shut-down of process flow. Therefore, it is import to ensure solving methods of slug flow at feed design stage. In the article, forming theory of slug flow is expatiated, and production slug flow, terrain slug flow and pigging slug flow are explained respectively. Simultaneously, defend measures are introduced in order to keep reliable operation. For a NanHai deepwater project, resolving concept is discussed with software OLGA.

  12. 微通道内气-液弹状流动及传质特性研究进展 (Review on flow and mass transfer characteristics of gas-liquid slug flow in microchannels)

    NARCIS (Netherlands)

    Yao, Chaoqun; Yue, Jun; Zhao, Yuchao; Chen, Guangwen; Yuan, Quan

    2015-01-01

    Gas-liquid slug flow (also termed as Taylor flow) is a flow pattern characterized by the alternate movement of elongated bubbles and liquid slugs. Gas-liquid slug flow operation in microchannels has been found important implications in the enhancement of gas-liquid reactions due to its advantages su

  13. Fermi/GBM Observations of SGR J0501+4516 Bursts

    CERN Document Server

    Lin, Lin; Baring, Matthew G; van der Horst, Alexander J; Guiriec, Sylvain; Woods, Peter M; Gogus, Ersin; Kaneko, Yuki; Scargle, Jeffrey; Granot, Jonathan; Preece, Robert; von Kienlin, Andreas; Chaplin, Vandiver; Watts, Anna L; Wijers, Ralph A M J; Zhang, Shuang Nan; Bhat, Narayan; Finger, Mark H; Gehrels, Neil; Harding, Alice; Kaper, Lex; Kaspi, Victoria; Mcenery, Julie; Meegan, Charles A; Paciesas, William S; Pe'er, Asaf; Ramirez-Ruiz, Enrico; van der Klis, Michiel; Wachter, Stefanie; Wilson-Hodge, Colleen

    2011-01-01

    We present our temporal and spectral analyses of 29 bursts from SGR J0501+4516, detected with the Gamma-ray Burst Monitor onboard the Fermi Gamma-ray Space Telescope during the 13 days of the source activation in 2008 (August 22 to September 3). We find that the T90 durations of the bursts can be fit with a log-normal distribution with a mean value of ~ 123 ms. We also estimate for the first time event durations of Soft Gamma Repeater (SGR) bursts in photon space (i.e., using their deconvolved spectra) and find that these are very similar to the T90s estimated in count space (following a log-normal distribution with a mean value of ~ 124 ms). We fit the time-integrated spectra for each burst and the time-resolved spectra of the five brightest bursts with several models. We find that a single power law with an exponential cutoff model fits all 29 bursts well, while 18 of the events can also be fit with two black body functions. We expand on the physical interpretation of these two models and we compare their p...

  14. Wire-mesh and ultrasound techniques applied for the characterization of gas-liquid slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Ofuchi, Cesar Y.; Sieczkowski, Wytila Chagas; Neves Junior, Flavio; Arruda, Lucia V.R.; Morales, Rigoberto E.M.; Amaral, Carlos E.F.; Silva, Marco J. da [Federal University of Technology of Parana, Curitiba, PR (Brazil)], e-mails: ofuchi@utfpr.edu.br, wytila@utfpr.edu.br, neves@utfpr.edu.br, lvrarruda@utfpr.edu.br, rmorales@utfpr.edu.br, camaral@utfpr.edu.br, mdasilva@utfpr.edu.br

    2010-07-01

    Gas-liquid two-phase flows are found in a broad range of industrial applications, such as chemical, petrochemical and nuclear industries and quite often determine the efficiency and safety of process and plants. Several experimental techniques have been proposed and applied to measure and quantify two-phase flows so far. In this experimental study the wire-mesh sensor and an ultrasound technique are used and comparatively evaluated to study two-phase slug flows in horizontal pipes. The wire-mesh is an imaging technique and thus appropriated for scientific studies while ultrasound-based technique is robust and non-intrusive and hence well suited for industrial applications. Based on the measured raw data it is possible to extract some specific slug flow parameters of interest such as mean void fraction and characteristic frequency. The experiments were performed in the Thermal Sciences Laboratory (LACIT) at UTFPR, Brazil, in which an experimental two-phase flow loop is available. The experimental flow loop comprises a horizontal acrylic pipe of 26 mm diameter and 9 m length. Water and air were used to produce the two phase flow under controlled conditions. The results show good agreement between the techniques. (author)

  15. Origin of the hungry caterpillar: Evolution of fasting in slug moths (Insecta: Lepidoptera: Limacodidae).

    Science.gov (United States)

    Zaspel, J M; Weller, S J; Epstein, M E

    2016-01-01

    Studies of caterpillar defense strategy evolution typically focus on aposematic coloration, gregarious behavior, and/or chemical defense. In the slug moth family Limacodidae, the evolution of chemical defense is coupled to the life history trait of first instar feeding behaviors. In nettle caterpillars, the first instars fast and molt into a second instar that feeds. In contrast, gelatines and monkey slug larval forms feed in the first instar. This study focused on whether the evolution of fasting associated with the nettle morphology was a derived trait of single or multiple origins. Twenty-nine species of Limacodidae (including one Chrysopolominae) representing 27 genera and four outgroup species with known first and final instar morphologies and behaviors were included. Four out-group species representing Megalopygidae (1 sp), Dalceridae (1 sp) and Aididae (2 sp) were included. These were sequenced for three molecular markers for a total of 4073 bp, mitochondrial COI (∼1500 bp), 18S (∼1900 bp) and the D2 region of 28S (approximately 670 bp). Maximum likelihood and Bayesian analyses were conducted. The resulting phylogeny and comparative analysis of feeding strategy revealed that the nettle caterpillar morphology and behavior of larval fasting may have a single origin. PMID:26432392

  16. Proposals for improving interphase drag modelling for the bubbly and slug regimes in RELAP5

    International Nuclear Information System (INIS)

    The proposal is put forward that the effective interphase drag coefficient for the bubbly and slug regimes in RELAP5 should be calculated using best-estimate void fraction correlations. It is argued that this will lead to improvements in the code's modelling of interphase drag and evidence is given to corroborate this. The need for such improvements has been prompted by the poor performance of the current models in simulating rod bundle experiments. There is also concern that the models do not account for profile slip effects, which could be important in a variety of geometries, and that the slug flow equations may not be appropriate for large diameter vertical pipes. To support the proposal, a set of void fraction correlations is identified which is believed to cover the full range of geometries and flow conditions encountered in PWR safety analysis including the analysis of small-scale experimental facilities. This set is selected from a detailed appraisal of the most appropriate correlations found in the literature which takes account of comparisons with experimental data and physical considerations. This Report forms part of the UK's commitment to the ICAP Code Improvement Plan. The recommendations will now be implemented in a development version of RELAP5/MOD3 and a preliminary assessment made. The interphase drag models used in the annular-mist regime will also be examined and, if necessary, appropriate improvements will be proposed. (author)

  17. A Review of the Multilevel Slug Test for Characterizing Aquifer Heterogeneity

    Directory of Open Access Journals (Sweden)

    Chia-Shyun Chen

    2012-01-01

    Full Text Available All aquifers are heterogeneous to a certain degree. The spatial distribution of hydraulic conductivity K(x, y, z, or aquifer heterogeneity, significantly influences the groundwater flow movement and associated solute transport. Of particular importance in designing an in-situ remediation plan is a knowledge of low-K layers because they are less accessible to remedial agents and form a bottleneck in remediation. The characterization of aquifer heterogeneity is essential to the solution of many practical and scientific groundwater problems. This article reviews the field technique using the multilevel slug test (MLST, which determines a series of K estimates at depths of interest in a well by making use of a double-packer system. The K(z obtained manifests the vertical variation of hydraulic conductivity in the vicinity of the test well, and the combination of K(z from different wells gives rise to a three-dimensional description of K(x, y, z. The MLST response is rather sensitive to hydraulic conductivity variation; e.g., it is oscillatory for highly permeable conditions (K > 5 × 10-4 m s-1 and a nonoscillatory for K < 5 × 10-4 m s-1. In this article we discuss the instrumentation of the double-packer system, the implementation of the depth-specific slug test, the data analysis methods for a spectrum of response characteristics usually observed in the field, and field applications of the MLST.

  18. Chondrogenic potential of human mesenchymal stem cells and expression of Slug transcription factor.

    Science.gov (United States)

    Brini, Anna T; Niada, Stefania; Lambertini, Elisabetta; Torreggiani, Elena; Arrigoni, Elena; Lisignoli, Gina; Piva, Roberta

    2015-06-01

    The scientific literature rarely reports experimental failures or inconsistent outcomes in the induction of cell differentiation; however, researchers commonly experience poor or unsuccessful responses to differentiating agents when culturing stem cells. One way of investigating the underlying reasons for such responses is to look at the basal expression levels of specific genes in multipotent stem cells before the induction of differentiation. In addition to shedding light on the complex properties of stem cells and the molecular modulation of differentiation pathways, this strategy can also lead to the development of important time- and money-saving tools that aid the efficient selection of cellular specimens--in this case, stem cells that are more prone to differentiate towards specific lineages and are therefore more suitable for cell-based therapeutic protocols in regenerative medicine. To address this latter aspect, this study focused on understanding the reasons why some human mesenchymal stem cell (hMSC) samples are less efficient at differentiating towards chondrogenesis. This study shows that analysis of the basal expression levels of Slug, a negative regulator of chondrogenesis in hMSC, provides a rapid and simple tool for distinguishing stem cell samples with the potential to form a cartilage-like matrix, and that are therefore suitable for cartilage tissue engineering. It is shown that high basal levels of Slug prevent the chondrogenic differentiation of hMSCs, even in the presence of transforming growth factor-β and elevated levels of Sox9.

  19. CFD Analysis of a Slug Mixing Experiment Conducted on a VVER-1000 Model

    Directory of Open Access Journals (Sweden)

    F. Moretti

    2009-01-01

    Full Text Available A commercial CFD code was applied, for validation purposes, to the simulation of a slug mixing experiment carried out at OKB “Gidropress” scaled facility in the framework of EC TACIS project R2.02/02: “Development of safety analysis capabilities for VVER-1000 transients involving spatial variations of coolant properties (temperature or boron concentration at core inlet.” Such experimental model reproduces a VVER-1000 nuclear reactor and is aimed at investigating the in-vessel mixing phenomena. The addressed experiment involves the start-up of one of the four reactor coolant pumps (the other three remaining idle, and the presence of a tracer slug on the starting loop, which is thus transported to the reactor pressure vessel where it mixes with the clear water. Such conditions may occur in a boron dilution scenario, hence the relevance of the addressed phenomena for nuclear reactor safety. Both a pretest and a posttest CFD simulations of the mentioned experiment were performed, which differ in the definition of the boundary conditions (based either on nominal quantities or on measured quantities, resp.. The numerical results are qualitatively and quantitatively analyzed and compared against the measured data in terms of space and time tracer distribution at the core inlet. The improvement of the results due to the optimization of the boundary conditions is evidenced, and a quantification of the simulation accuracy is proposed.

  20. Drought tolerance in eggs and juveniles of the Iberian slug, Arion lusitanicus.

    Science.gov (United States)

    Slotsbo, Stine; Fisker, Karina Vincents; Hansen, Lars Monrad; Holmstrup, Martin

    2011-12-01

    The spread of invasive species is an increasing problem world wide. The invasive slug Arion lusitanicus has spread to most parts of Europe, where it often is considered as a serious pest. There is a need for better knowledge of its ecophysiology to be able to predict the effect of climatic factors, such as temperature and humidity on the population dynamics and abundance. The aim of the present study was to assemble data on the water balance and drought tolerance of eggs and juveniles of A. lusitanicus. Both eggs and juveniles had little capacity to prevent evaporative water loss and lost water when the ambient humidity fell below 99.8 and 99.5%, respectively. The water conductance of the cuticle of juveniles was 242 μg cm(-2) h(-1) mmHg(-1) and resembles that of other slug species. Both eggs and juveniles of A. lusitanicus tolerate a substantial water loss. There was no difference in water loss resistance between eggs and juveniles, but the eggs were slightly more tolerant to water loss than the juveniles. The percent water loss causing 50% mortality was 72% for the juveniles and 81% for the eggs. Despite A. lusitanicus' tolerance of substantial water loss, its survival depends on humid habitats.

  1. Detection of Spectral Evolution in the Bursts Emitted During the 2008-2009 Active Episode of SGR J1550 - 5418

    Science.gov (United States)

    von Kienlin, Andreas; Gruber, David; Kouveliotou, Chryssa; Granot, Jonathan; Baring, Matthew G.; Gogus, Ersin; Huppenkothen, Daniela; Kaneko, Yuki; Lin, Lin; Watts, Anna L.; Bhat, Narayana; Guiriec, Sylvain; van der Horst, Alexander J.; Bissaldi, Elisabetta; Greiner, Jochen; Meegan, Charles A.; Paciesas, William S.; Preece, Robert D.; Rau, Arne

    2012-01-01

    In early October 2008, the Soft Gamma Repeater SGRJ1550 - 5418 (1E1547.0 - 5408, AXJ155052 - 5418, PSR J1550 - 5418) became active, emitting a series of bursts which triggered the Fermi Gamma-ray Burst Monitor (GBM) after which a second especially intense activity period commenced in 2009 January and a third, less active period was detected in 2009 March-April. Here we analyze the GBM data of all the bursts from the first and last active episodes. We performed temporal and spectral analysis for all events and found that their temporal characteristics are very similar to the ones of other SGR bursts, as well the ones reported for the bursts of the main episode (average burst durations 170ms). In addition, we used our sample of bursts to quantify the systematic uncertainties of the GBM location algorithm for soft gamma-ray transients to less than or equal to 8 degrees. Our spectral analysis indicates significant spectral evolution between the first and last set of events. Although the 2008 October events are best fit with a single blackbody function, for the 2009 bursts an Optically Thin Thermal Bremsstrahlung (OTTB) is clearly preferred. We attribute this evolution to changes in the magnetic field topology of the source, possibly due to effects following the very energetic main bursting episode.

  2. The 2006-2007 Active Phase of Anomalous X-ray Pulsar 4U 0142+61: Radiative and Timing Changes, Bursts, and Burst Spectral Features

    CERN Document Server

    Gavriil, Fotis P; Kaspi, Victoria M

    2009-01-01

    After at least 6 years of quiescence, Anomalous X-ray Pulsar (AXP) 4U 0142+61 entered an active phase in 2006 March that lasted several months and included six X-ray bursts as well as many changes in the persistent X-ray emission. The bursts, the first seen from this AXP in >11 years of Rossi X-ray Timing Explorer monitoring, all occurred in the interval between 2006 April 6 and 2007 February 7. The burst durations ranged from 8-3x10^3 s. The first five burst spectra are well modeled by blackbodies, with temperatures kT ~ 2-6 keV. However, the sixth burst had a complicated spectrum that is well characterized by a blackbody plus three emission features whose amplitude varied throughout the burst. The most prominent feature was at 14.0 keV. Upon entry into the active phase the pulsar showed a significant change in pulse morphology and a likely timing glitch. The glitch had a total frequency jump of 1.9+/-0.4 x 10^-7 Hz, which recovered with a decay time of 17+/-2 days by more than the initial jump, implying a n...

  3. Online recognition of the multiphase flow regime and study of slug flow in pipeline

    Science.gov (United States)

    Liejin, Guo; Bofeng, Bai; Liang, Zhao; Xin, Wang; Hanyang, Gu

    2009-02-01

    single sensor performance. Among various flow patterns of gas-liquid flow, slug flow occurs frequently in the petroleum, chemical, civil and nuclear industries. In the offshore oil and gas field, the maximum slug length and its statistical distribution are very important for the design of separator and downstream processing facility at steady state operations. However transient conditions may be encountered in the production, such as operational upsets, start-up, shut-down, pigging and blowdown, which are key operational and safety issues related to oil field development. So it is necessary to have an understanding the flow parameters under transient conditions. In this paper, the evolution of slug length along a horizontal pipe in gas-liquid flow is also studied in details and then an experimental study of flowrate transients in slug flow is provided. Also, the special gas-liquid flow phenomena easily encountered in the life span of offshore oil fields, called severe slugging, is studied experimentally and some results are presented.

  4. Online recognition of the multiphase flow regime and study of slug flow in pipeline

    Energy Technology Data Exchange (ETDEWEB)

    Guo Liejin; Bai Bofeng; Zhao Liang; Wang Xin; Gu Hanyang, E-mail: lj-guo@mail.xjtu.edu.c [Xi' an Jiaotong University, Xi' an 710049 (China)

    2009-02-01

    sensor performance. Among various flow patterns of gas-liquid flow, slug flow occurs frequently in the petroleum, chemical, civil and nuclear industries. In the offshore oil and gas field, the maximum slug length and its statistical distribution are very important for the design of separator and downstream processing facility at steady state operations. However transient conditions may be encountered in the production, such as operational upsets, start-up, shut-down, pigging and blowdown, which are key operational and safety issues related to oil field development. So it is necessary to have an understanding the flow parameters under transient conditions. In this paper, the evolution of slug length along a horizontal pipe in gas-liquid flow is also studied in details and then an experimental study of flowrate transients in slug flow is provided. Also, the special gas-liquid flow phenomena easily encountered in the life span of offshore oil fields, called severe slugging, is studied experimentally and some results are presented.

  5. Observations of Gamma-ray Bursts in the Fermi era

    CERN Document Server

    Vianello, Giacomo

    2013-01-01

    The Fermi observatory, with its Gamma-Ray Bursts monitor (GBM) and Large Area Telescope (LAT), is observing Gamma-ray Bursts with unprecedented spectral coverage and sensitivity, from ~10 keV to > 300 GeV. In the first 3 years of the mission it observed emission above 100 MeV from 35 GRBs, an order of magnitude gain with respect to previous observations in this energy range. In this paper we review the main results obtained on such sample, highlighting also the relationships with the low-energy features (as measured by the GBM), and with measurements from observatories at other wavelengths. We also briefly discuss prospects for detection of GRBs by future Very-High Energy observatories such as HAWC and CTA, and by Gravitational Wave experiments.

  6. Physics of gamma-ray bursts

    Science.gov (United States)

    Lamb, D. Q.

    1984-01-01

    Attention is given to the accumulating evidence for the view that gamma-ray bursts come from strongly magnetic neutron stars, discussing the physical properties of the emission region and the radiation processes expected in strong magnetic fields, and emphasizing that the observed burst spectra require that the emission region be optically thin. This entails that the energy of the emitting plasma and/or the plasma itself be continuously replenished during a burst, and that the cooling time scale of the emitting plasma be much shorter than the observed duration of the bursts. This characteristic of the cooling time scale implies that the burst intensity and spectrum can vary on extremely short time scales, and that the burst duration must have a separate explanation. It is emphasized that synchrotron emission is favored as the gamma-ray production mechanism; it is the only mechanism capable of satisfying the optical thinness constraint while producing the observed luminosity.

  7. Pulse Phase Dependence of the Magnetar Bursts

    Indian Academy of Sciences (India)

    Chetana Jain; Anjan Dutta; Biswajit Paul

    2007-12-01

    We report here results from a study of X-ray bursts from 3 magnetar candidates (SGR 1806–20, SGR 1900+14 and AXP 1E 2259+586). We have searched for a pulse phase dependence of the X-ray burst rate from these sources. X-ray light curves were obtained with the Proportional Counter Array on-board the Rossi X-ray Timing Explorer during the periods of intense burst activity in these sources. On detailed analysis of the three sources, we found a very significant burst rate for all pulsar phases. However, some locations appear to produce bursts slightly more often, rendering the non-isotropic distribution. Only in the case of SGR 1900+14, there is a clear pulse phase dependence of burst rate.

  8. Bursting for enhanced ablation of materials

    Science.gov (United States)

    Hendow, Sami; Rea, Edward; Kosa, Nadhir; Bengtsson, Magnus; Shakir, Sami

    2014-03-01

    A significant enhancement in the rate of material removal is demonstrated using a nanosecond-pulsed UV fiber laser in multi-pulsing burst mode, as compared to the case without bursting. Percussion drilling and scribing of thin-film and bulk material tests show that, in general, laser bursts with increased pulse count and reduced pulse spacing show higher rates of material removal. A considerable improvement in removal rate is demonstrated, when bursting is applied to scribing of mono-crystalline silicon (m-Si) and up to 30% in percussion drilling speed. Likewise, improved material removal is demonstrated for scribing of thin film of indium tin oxide (ITO) on glass or metal film on sapphire. Examples of material processing are given with and without bursting at similar experimental conditions of average power, scan speed, and burst/pulse energies. Experimental results included are for m-Si, ITO thin films on glass, and metal films on sapphire.

  9. Banana Slug

    Science.gov (United States)

    First, Lucas

    2009-01-01

    Everyone insists that a person should go to a college that is right for him/her, somewhere that fits who he/she is, a place where a they belong. There are more than 4,000 colleges and universities in this country; how will a person find the one that is right for them? In this article, the author suggests that one should follow the mascot when…

  10. United assembly algorithm for optical burst switching

    Institute of Scientific and Technical Information of China (English)

    Jinhui Yu(于金辉); Yijun Yang(杨教军); Yuehua Chen(陈月华); Ge Fan(范戈)

    2003-01-01

    Optical burst switching (OBS) is a promising optical switching technology. The burst assembly algorithm controls burst assembly, which significantly impacts performance of OBS network. This paper provides a new assembly algorithm, united assembly algorithm, which has more practicability than conventional algorithms. In addition, some factors impacting selections of parameters of this algorithm are discussed and the performance of this algorithm is studied by computer simulation.

  11. Bubble burst as jamming phase transition

    CERN Document Server

    Nishinari, Katsuhiro; Saito, Yukiko Umeno; Watanabe, Tsutomu

    2010-01-01

    Recently research on bubble and its burst attract much interest of researchers in various field such as economics and physics. Economists have been regarding bubble as a disorder in prices. However, this research strategy has overlooked an importance of the volume of transactions. In this paper, we have proposed a bubble burst model by focusing the transactions incorporating a traffic model that represents spontaneous traffic jam. We find that the phenomenon of bubble burst shares many similar properties with traffic jam formation by comparing data taken from US housing market. Our result suggests that the transaction could be a driving force of bursting phenomenon.

  12. Two classes of gamma-ray bursts

    CERN Document Server

    Katz, J I

    1995-01-01

    Data from the 3B Catalogue suggest that short and long GRB are the results of different classes of events, rather than different parameter values within a single class: Short bursts have harder spectra in the BATSE bands, but chiefly long bursts are detected at photon energies over 1 MeV, implying that their hard photons are radiated by a process not found in short bursts. The values of \\langle V/V_{max} \\rangle for short and long bursts differ by 4.3 \\sigma, implying different spatial distributions. Only the soft gamma-ray radiation mechanisms are the same in both classes.

  13. Bursting behaviour in coupled Josephson junctions.

    Science.gov (United States)

    Hongray, Thotreithem; Balakrishnan, J; Dana, Syamal K

    2015-12-01

    We report an interesting bow-tie shaped bursting behaviour in a certain parameter regime of two resistive-capacitative shunted Josephson junctions, one in the oscillatory and the other in the excitable mode and coupled together resistively. The burst emerges in both the junctions and they show near-complete synchronization for strong enough couplings. We discuss a possible bifurcation scenario to explain the origin of the burst. An exhaustive study on the parameter space of the system is performed, demarcating the regions of bursting from other solutions. PMID:26723143

  14. Gamma-Ray Bursts 2012 Conference

    Science.gov (United States)

    It is a pleasure to announce the next combined Fermi/Swift GRB conference covering recent advances in all aspects of gamma-ray burst observations and theory. This conference will be held in Munich, Germany, on 7-11 May 2012, and follows similar previous combined Fermi/Swift meetings in Huntsville (Oct. 2008) and Annapolis (Nov. 2010). Gamma-ray bursts are the most energetic explosions in the Universe and are thought to be the birth signatures of black holes. This is an exciting time in the GRB field as various missions provide a wealth of new data on this still puzzling phenomenon. The Fermi misson provides unprecedented spectral coverage over 7 decades in energy, and among others discovered new spectral components which challenge our standard picture of the prompt emission. The Swift mission continuous to swiftly monitor and locate GRBs in multiple wavebands, providing the basis for all ground-based follow-up observations towards redshift measurements and afterglow and host property investigations. AGILE, INTEGRAL, Suzaku and Konus continue to provide crucial information on GRB properties, and the MAXI mission provides an all sky X-ray monitoring of transients. There is also growing capability for follow-up observations by ground-based telescopes at basically all wavelengths. Besides the classical optical/infrared/radio observations, searches are underway for TeV emission, neutrinos and gravitational waves. Moreover, new experiments are expected to have returned first data, among others POGO on the prompt polarization properties, UFFO on very early optical emission, or ALMA on sub-millimeter properties. And last but not least, the unexpected is bringing us child-like astonishments at least once per year with a "GRB-trigger" which turns out to be not related to GRBs. Complementing all these new observational results, a huge theoretical effort is underway to understand the GRB phenomenon and keep up with the constant new puzzles coming from the data. This conference

  15. The effect of climate manipulations on the herbivory of the pest slug Deroceras reticulatum (Müller, 1774) (Pulmonata: Agriolimacidae)

    Science.gov (United States)

    El-Danasoury, H.; Iglesias-Piñeiro, J.; Córdoba, M.

    2016-01-01

    The pestiferous status of the terrestrial slug Deroceras reticulatum and the strong dependence of its biology and ecology on climatic factors have driven research on the potential responses of the slug to predicted scenarios of climate change. Here, we report two short-term experiments performed outdoors, under seminatural conditions, to assess the behavioural response of D. reticulatum to different climate manipulations in terms of herbivory, by measuring over 7 days the damage inflicted by slug populations to lettuce seedlings. The climate manipulations tested emulate predicted climatic conditions for northwest Spain, specifically winter warming and increased summer rainfall, in contrast respectively with normal winter conditions and summer without rain conditions. In a winter experiment, we compared a normal winter treatment with a winter warming treatment; with respect to the normal winter treatment, the winter warming treatment was characterised by higher temperature, lower relative humidity and the absence of rainfall. In a summer experiment, we compared a summer drought treatment with an increased summer rainfall treatment; with respect to the summer drought treatment, the increased summer rainfall treatment was characterised by the presence of rainfall, while the conditions of temperature and relative humidity were similar in both treatments. Neither winter warming nor increased summer rainfall did lead to a significant increase on the number of seedlings damaged by the slugs. However, with both treatments, we found a moderate increase on the amount of damage suffered by the seedlings. The results are discussed in the context of the potential responses of D. reticulatum to future climatic conditions.

  16. MATHEMATICAL MODELING OF THE PROCESSES OF RADIATION-CONVECTIVE HEAT EXCHANGE AT HEATING OF STEEL SLUGS IN METHODICAL TRANSFER FURNACES

    Directory of Open Access Journals (Sweden)

    I. A. Trusova

    2010-01-01

    Full Text Available The investigations on rational placement of burner devices in reheating furnaces with mechanized sole at the example of reheating furnace of mill 850 of RUP “BMZ” and determination of their force in dependence with grade assortment and slugs dimension types are given.

  17. Terrestrial Slugs as a Model Organism for Inquiry-Based Experimentation in a Majors General Biology Laboratory

    Science.gov (United States)

    Peters, Brenda J.; Blair, Amy C.

    2013-01-01

    Many biology educators at the undergraduate level are revamping their laboratory curricula to incorporate inquiry-based research experiences so that students can directly participate in the process of science and improve their scientific reasoning skills. Slugs are an ideal organism for use in such a student-directed, hypothesis-driven experience.…

  18. Field experiments using the rhabditid nematode Phasmarhabditis hermaphrodita or salt as control measures against slugs in green asparagus

    NARCIS (Netherlands)

    Ester, A.; Rozen, van K.; Molendijk, L.P.G.

    2003-01-01

    Green asparagus (Asparagus officinalis L.) crops are frequently damaged by the grey field slug (Deroceras reticulatum). Most damage occurs in the soil, although some asparagus spears are attacked above ground. In the Netherlands damage occurs especially during the first 5 weeks of harvesting, from t

  19. Plastid-bearing sea slugs fix CO2 in the light but do not require photosynthesis to survive

    NARCIS (Netherlands)

    G. Christa (Gregor); V. Zimorski (Verena); C. Woehle (Christian); A.G.M. Tielens (Aloysius); H. Wägele (Heike); W. Martin (William); D.B. Gould (Douglas )

    2013-01-01

    textabstractSeveral sacoglossan sea slugs (Plakobranchoidea) feed upon plastids of large unicellular algae. Four species-called long-term retention (LtR) species-are known to sequester ingested plastids within specialized cells of the digestive gland. There, the stolen plastids (kleptoplasts) remain

  20. Plastid-bearing sea slugs fix CO2 in the light but do not require photosynthesis to survive

    NARCIS (Netherlands)

    Christa, Gregor; Zimorski, Verena; Woehle, Christian; Tielens, Aloysius G M; Wägele, Heike; Martin, William F; Gould, Sven B

    2014-01-01

    Several sacoglossan sea slugs (Plakobranchoidea) feed upon plastids of large unicellular algae. Four species--called long-term retention (LtR) species--are known to sequester ingested plastids within specialized cells of the digestive gland. There, the stolen plastids (kleptoplasts) remain photosynt

  1. Helium bubble bursting in tungsten

    Energy Technology Data Exchange (ETDEWEB)

    Sefta, Faiza [University of California, Berkeley, California 94720 (United States); Juslin, Niklas [University of Tennessee, Knoxville, Tennessee 37996 (United States); Wirth, Brian D., E-mail: bdwirth@utk.edu [University of Tennessee, Oak Ridge National Laboratory, Knoxville, Tennessee 37996 (United States)

    2013-12-28

    Molecular dynamics simulations have been used to systematically study the pressure evolution and bursting behavior of sub-surface helium bubbles and the resulting tungsten surface morphology. This study specifically investigates how bubble shape and size, temperature, tungsten surface orientation, and ligament thickness above the bubble influence bubble stability and surface evolution. The tungsten surface is roughened by a combination of adatom “islands,” craters, and pinholes. The present study provides insight into the mechanisms and conditions leading to various tungsten topology changes, which we believe are the initial stages of surface evolution leading to the formation of nanoscale fuzz.

  2. 水平管内油气两相弹状流的产生%AN EXPERIMENTAL INVESTIGATION ON ONSET OF SLUGGING IN HORIZONTAL OIL-GAS PIPE FLOW

    Institute of Scientific and Technical Information of China (English)

    蔡继勇; 罗毓珊; 陈听宽

    1999-01-01

    In this paper,the method of linear stability analysis is used to study the onset of slugging for oil-gas two-phase flow in a horizontal tube.The relation between the appearance of wavy stratified flow,the formation of slugs and the transition to stable slug flow is quantitatively investigated.A criterion for the transition to stable slug flow is derived from an initial condition of slug growth.The results analysed by the theoretical method compare well with the experimental results.

  3. Transcriptional burst frequency and burst size are equally modulated across the human genome

    Energy Technology Data Exchange (ETDEWEB)

    Dar, Roy D. [University of Tennessee, Knoxville (UTK); Simpson, Michael L [ORNL; Weinberger, Leor S. [University of California, San Diego; Razooky, B [University of California, San Diego; Cox, Chris D. [University of Tennessee, Knoxville (UTK); McCollum, James M. [Miami University; Trimeloni, Tom [Virginia Commonwealth University, Richland; Singh, A [University of California, San Diego

    2012-01-01

    Gene expression occurs either as an episodic process, characterized by pulsatile bursts or as a constitutive, Poisson-like accumulation of gene products. It is not clear which mode of gene expression (constitutive versus bursty) predominates across a genome or how transcriptional dynamics are influenced by genomic position and promoter sequence. Here, we use time-lapse fluorescence microscopy, building off of theoretical studies that exploit the time-resolved structure of stochastic fluctuations in gene expression, to develop a three-dimensional method for mapping underlying gene-regulatory mechanisms. Over 8,000 individual human genomic loci were analyzed, and at virtually all loci, episodic bursting as opposed to constitutive expression was found to be the predominant mode of expression. Quantitative analysis of the expression dynamics at these 8,000 loci indicates that both frequency and size of transcriptional bursts vary equally across the human genome independent of promoter sequence. Strikingly, weaker expression loci modulate burst frequency to increase activity, while stronger expression loci modulate burst size to increase activity. Transcriptional activators, such as TNF, generate similar patterns of change in burst frequency and burst size. In summary, transcriptional bursting dominates across the human genome, both burst frequency and burst size vary by chromosomal location, and transcriptional activators alter burst frequency and burst size, depending on the expression level of the locus.

  4. Analysis of historic bursts and burst detection in water supply areas of different size

    NARCIS (Netherlands)

    Bakker, M.; Trietsch, E.A.; Vreeburg, J.H.G.; Rietveld, L.C.

    2014-01-01

    Pipe bursts in water distribution networks lead to water losses and a risk of damaging the urban environment. We studied hydraulic data and customer contact records of 44 real bursts for a better understanding of the phenomena. We found that most bursts were reported to the water company shortly aft

  5. Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

    Directory of Open Access Journals (Sweden)

    Bhatnagar Dinesh

    2009-09-01

    Full Text Available Abstract Background Cancer progression is linked to a partially dedifferentiated epithelial cell phenotype. The signaling pathways Wnt, Hedgehog, TGF-β and Notch have been implicated in experimental and developmental epithelial mesenchymal transition (EMT. Recent findings from our laboratory confirm that active Wnt/β-catenin signaling is critically involved in invasive ductal carcinomas (IDCs of breast. Methods In the current study, we analyzed the expression patterns and relationships between the key Wnt/β-catenin signaling components- E-cadherin, Slug and GSK3β in IDCs of breast. Results Of the 98 IDCs analyzed, 53 (54% showed loss/or reduced membranous staining of E-cadherin in tumor cells. Nuclear accumulation of Slug was observed in 33 (34% IDCs examined. Loss or reduced level of cytoplasmic GSK3β expression was observed in 52/98 (53% cases; while 34/98 (35% tumors showed nuclear accumulation of GSK3β. Statistical analysis revealed associations of nuclear Slug expression with loss of membranous E-cadherin (p = 0.001; nuclear β-catenin (p = 0.001, and cytoplasmic β-catenin (p = 0.005, suggesting Slug mediated E-cadherin suppression via the activation of Wnt/β-catenin signaling pathway in IDCs. Our study also demonstrated significant correlation between GSK3β nuclear localization and tumor grade (p = 0.02, suggesting its association with tumor progression. Conclusion The present study for the first time provided the clinical evidence in support of Wnt/β-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3β with β-catenin in implementing EMT in these cells.

  6. Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression.

    Science.gov (United States)

    Pan, Yi; Li, Jing; Zhang, Yaqin; Wang, Nan; Liang, Hongwei; Liu, Yuan; Zhang, Chen-Yu; Zen, Ke; Gu, Hongwei

    2016-01-01

    It is generally regarded that E-cadherin is downregulated during tumorigenesis via Snail/Slug-mediated E-cadherin transcriptional reduction. However, this transcriptional suppressive mechanism cannot explain the failure of producing E-cadherin protein in metastatic breast cancer cells after overexpressing E-cadherin mRNA. Here we reveal a novel mechanism that E-cadherin is post-transcriptionally regulated by Slug-promoted miR-221, which serves as an additional blocker for E-cadherin expression in metastatic tumor cells. Profiling the predicted E-cadherin-targeting miRNAs in breast cancer tissues and cells showed that miR-221 was abundantly expressed in breast tumor and metastatic MDA-MB-231 cells and its level was significantly higher in breast tumor or MDA-MB-231 cells than in distal non-tumor tissue and low-metastatic MCF-7 cells, respectively. MiR-221, which level inversely correlated with E-cadherin level in breast cancer cells, targeted E-cadherin mRNA open reading frame (ORF) and suppressed E-cadherin protein expression. Depleting or increasing miR-221 level in breast cancer cells induced or decreased E-cadherin protein level, leading to suppressing or promoting tumor cell progression, respectively. Moreover, miR-221 was specifically upregulated by Slug but not Snail. TGF-β treatment enhanced Slug activity and thus increased miR-221 level in MCF-7 cells. In summary, our results provide the first evidence that Slug-upregulated miR-221 promotes breast cancer progression via reducing E-cadherin expression. PMID:27174021

  7. 应用拱顶沉降监测技术预报软弱围岩隧道突泥突水%The Application of the Monitoring Techniques for Vault Settlement to the Forecast of Water and. Mud Burst from the Soft

    Institute of Scientific and Technical Information of China (English)

    史付生

    2011-01-01

    In soft-rocked tunnels, water will build up pressure which may lead to the deformation of the surrounding rock of the tunnel, as a result of which the possibility of water and mud burst may be predicted by monitoring the displacement rate of the vault nea%在隧道软弱岩层中存在具有一定压力的水体会使周边围岩产生变形,因此可通过监测临近掌子面的拱顶位移速率来推测前方是否可能发生突水突泥。具体过程为通过统计已有测量的拱顶下沉速率量与突水突泥的事件发生的相关度,得出一个阈值。然后,根据这个阈值来推测前方是否可能发生突泥突水。石林软岩隧道的应用实例说明此方法具体可行,为超前地质预报提供了一个新的途径。

  8. Spatial variability of hydraulic conductivity of an unconfined sandy aquifer determined by a mini slug test

    DEFF Research Database (Denmark)

    Bjerg, Poul Løgstrup; Hinsby, Klaus; Christensen, Thomas Højlund;

    1992-01-01

    The spatial variability of the hydraulic conductivity in a sandy aquifer has been determined by a mini slug test method. The hydraulic conductivity (K) of the aquifer has a geometric mean of 5.05 × 10−4 m s−1, and an overall variance of 1n K equal to 0.37 which corresponds quite well to the results...... obtained by two large scale tracer experiments performed in the aquifer. A geological model of the aquifer based on 31 sediment cores, proposed three hydrogeological layers in the aquifer concurrent with the vertical variations observed with respect to hydraulic conductivity. The horizontal correlation...... length of the hydraulic conductivity has been determined for each of the three hydrogeological layers and is found to be small (1–2.5 m). The asymptotic longitudinal dispersivity of the aquifer has been estimated from the variance in hydraulic conductivity and the horizontal correlation length...

  9. Sea slugs, subliminal pictures and vegetative state patients: Boundaries of consciousness in classical conditioning.

    Directory of Open Access Journals (Sweden)

    Tristan A Bekinschtein

    2011-12-01

    Full Text Available Classical (trace conditioning is a specific variant of associative learning in which a neutral stimulus leads to the subsequent prediction of an emotionally charged or noxious stimulus after a temporal gap. When conditioning is concurrent with a distraction task, only participants who can report the relationship (the contingency between stimuli explicitly show associative learning. This suggests that consciousness is a prerequisite for trace conditioning. We review and question three main controversies concerning this view. Firstly, virtually all animals, even invertebrate sea slugs, show this type of learning; secondly, unconsciously perceived stimuli may elicit trace conditioning; and thirdly, some vegetative state patients show trace learning. We discuss and analyze these seemingly contradictory arguments to find the theoretical boundaries of consciousness in classical conditioning. We conclude that trace conditioning remains one of the best measures to test conscious processing in the absence of explicit reports.

  10. Study on the tuning of the DTL cavity using slug tuners

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, H. J.; Jo, Y. S.; Shim, C. B. [KAERI, Taejon (Korea, Republic of)

    2003-07-01

    20MeV DTL (Drift Tube Linac) is being developed as a low energy proton accelerator by PEFP (Proton Engineering Frontier Project). A DTL cavity consists of several tens of cells, and the errors of resonant frequency and accelerating field profile of the DTL cavity produced by machining and alignment errors can be adjusted and corrected by using slug tuners. To reduce time and effort to tune the cavity, tuning method including resonant frequency adjustment and field profile correction was developed. To validate the tuning method, numerical simulation about the first tank of the DTL was carried out. In this paper, the summary of the proposed tuning method and the simulation results are presented.

  11. SLUG - Stochastically Lighting Up Galaxies. II: Quantifying the Effects of Stochasticity on Star Formation Rate Indicators

    CERN Document Server

    da Silva, Robert L; Krumholz, Mark R

    2014-01-01

    The integrated light of a stellar population, measured through photometric filters that are sensitive to the presence of young stars, is often used to infer the star formation rate (SFR) for that population. However, these techniques rely on an assumption that star formation is a continuous process, whereas in reality stars form in discrete spatially- and temporally-correlated structures. This discreteness causes the light output to undergo significant time-dependent fluctuations, which, if not accounted for, introduce errors and biases in the inferred SFRs. We use SLUG (a code that Stochastically Lights Up Galaxies) to simulate galaxies undergoing stochastic star formation. We then use these simulations to present a quantitative analysis of these effects and provide tools for calculating probability distribution functions of SFRs given a set of observations. We show that, depending on the SFR tracer used, stochastic fluctuations can produce non-trivial errors at SFRs as high as 1 Msun/yr, and we suggest meth...

  12. Transition from slug to annular flow in horizontal air-water flow

    International Nuclear Information System (INIS)

    The transition from slug to annular flow in horizontal air-water and steam-water flow was investigated. Test sections of 50; 66.6 and 80 mm ID were used. The system pressure was 0.2 and 0.5 MPa in the air-water experiments and 2.5; 5; 7.5 and 10 MPa in the steam-water experiments. For flow pattern detection local impedance probes were used. This method was compared in a part of the experiments with differential pressure and gamma-beam measurements. The flow regime boundary is shifting strongly to smaller values of the superficial gas velocity with increasing pressure. Correlations from literature fit unsatisfactorily the experimental results. A new correlation is presented. (orig.)

  13. Coupling and noise induced spiking-bursting transition in a parabolic bursting model.

    Science.gov (United States)

    Ji, Lin; Zhang, Jia; Lang, Xiufeng; Zhang, Xiuhui

    2013-03-01

    The transition from tonic spiking to bursting is an important dynamic process that carry physiologically relevant information. In this work, coupling and noise induced spiking-bursting transition is investigated in a parabolic bursting model with specific discussion on their cooperation effects. Fast/slow analysis shows that weak coupling may help to induce the bursting by changing the geometric property of the fast subsystem so that the original unstable periodical solution are stabilized. It turned out that noise can play the similar stabilization role and induce bursting at appropriate moderate intensity. However, their cooperation may either strengthen or weaken the overall effect depending on the choice of noise level.

  14. The role of genetic and chemical variation of Pinus sylvestris seedlings in influencing slug herbivory.

    Science.gov (United States)

    O'Reilly-Wapstra, Julianne M; Iason, Glenn R; Thoss, Vera

    2007-05-01

    This study investigated the genetic and chemical basis of resistance of Pinus sylvestris seedlings to herbivory by a generalist mollusc, Arion ater. Using feeding trials with captive animals, we examined selective herbivory by A. ater of young P. sylvestris seedlings of different genotypes and correlated preferences with seedling monoterpene levels. We also investigated the feeding responses of A. ater to artificial diets laced with two monoterpenes, Delta(3)-carene and alpha-pinene. Logistic regression indicated that two factors were the best predictors of whether seedlings in the trial would be consumed. Individual slug variation (replicates) was the most significant factor in the model; however, alpha-pinene concentration (also representing beta-pinene, Delta(3)-carene and total monoterpenes due to multicollinearity) of needles was also a significant factor. While A. ater did not select seedlings on the basis of family, seedlings not eaten were significantly higher in levels of alpha-pinene compared to seedlings that were consumed. We also demonstrated significant genetic variation in alpha-pinene concentration of seedlings between different families of P. sylvestris. Nitrogen and three morphological seedling characteristics (stem length, needle length and stem diameter) also showed significant genetic variation between P. sylvestris families. Artificial diets laced with high (5 mg g(-1) dry matter) quantities of either Delta(3)-carene or alpha-pinene, were eaten significantly less than control diets with no added monoterpenes, supporting the results of the seedling feeding trial. This study demonstrates that A. ater selectively feed on P. sylvestris seedlings and that this selection is based, in part, on the monoterpene concentration of seedlings. These results, coupled with significant genetic variation in alpha-pinene concentration of seedlings and evidence that slug herbivory is detrimental to P. sylvestris fitness, are discussed as possible evidence for A

  15. The Case of the Disappearing Spindle Burst.

    Science.gov (United States)

    Tiriac, Alexandre; Blumberg, Mark S

    2016-01-01

    Sleep spindles are brief cortical oscillations at 10-15 Hz that occur predominantly during non-REM (quiet) sleep in adult mammals and are thought to contribute to learning and memory. Spindle bursts are phenomenologically similar to sleep spindles, but they occur predominantly in early infancy and are triggered by peripheral sensory activity (e.g., by retinal waves); accordingly, spindle bursts are thought to organize neural networks in the developing brain and establish functional links with the sensory periphery. Whereas the spontaneous retinal waves that trigger spindle bursts in visual cortex are a transient feature of early development, the myoclonic twitches that drive spindle bursts in sensorimotor cortex persist into adulthood. Moreover, twitches-and their associated spindle bursts-occur exclusively during REM (active) sleep. Curiously, despite the persistence of twitching into adulthood, twitch-related spindle bursts have not been reported in adult sensorimotor cortex. This raises the question of whether such spindle burst activity does not occur in adulthood or, alternatively, occurs but has yet to be discovered. If twitch-related spindle bursts do occur in adults, they could contribute to the calibration, maintenance, and repair of sensorimotor systems. PMID:27119028

  16. Photospheric radius expansion during magnetar bursts

    NARCIS (Netherlands)

    A.L. Watts; C. Kouveliotou; A.J. van der Horst; E. Göğüş; Y. Kaneko; M. van der Klis; R.A.M.J. Wijers; A.K. Harding; M.G. Baring

    2010-01-01

    On 2008 August 24 the new magnetar SGR 0501+4516 (discovered by Swift) emitted a bright burst with a pronounced double-peaked structure in hard X-rays, reminiscent of the double-peaked temporal structure seen in some bright thermonuclear bursts on accreting neutron stars. In the latter case this is

  17. The SVOM gamma-ray burst mission

    CERN Document Server

    Cordier, B; Atteia, J -L; Basa, S; Claret, A; Daigne, F; Deng, J; Dong, Y; Godet, O; Goldwurm, A; Götz, D; Han, X; Klotz, A; Lachaud, C; Osborne, J; Qiu, Y; Schanne, S; Wu, B; Wang, J; Wu, C; Xin, L; Zhang, B; Zhang, S -N

    2015-01-01

    We briefly present the science capabilities, the instruments, the operations, and the expected performance of the SVOM mission. SVOM (Space-based multiband astronomical Variable Objects Monitor) is a Chinese-French space mission dedicated to the study of Gamma-Ray Bursts (GRBs) in the next decade. The SVOM mission encompasses a satellite carrying four instruments to detect and localize the prompt GRB emission and measure the evolution of the afterglow in the visible band and in X-rays, a VHF communication system enabling the fast transmission of SVOM alerts to the ground, and a ground segment including a wide angle camera and two follow-up telescopes. The pointing strategy of the satellite has been optimized to favor the detection of GRBs located in the night hemisphere. This strategy enables the study of the optical emission in the first minutes after the GRB with robotic observatories and the early spectroscopy of the optical afterglow with large telescopes to measure the redshifts. The study of GRBs in the...

  18. TORTORA discovery of Naked-Eye Burst fast optical variability

    Science.gov (United States)

    Beskin, Grigory; Karpov, Sergey; Bondar, Sergey; Greco, Giuseppe; Guarnieri, Adriano; Bartolini, Corrado; Piccioni, Adalberto; Molinari, Emilio; Chincarini, Guido

    2008-10-01

    Features characterizing gamma-ray bursts in the different spectral bands may be a clue for the nature of their inner engine. Up to now, only several bursts have been observed in optical band during the gamma activity, and the only one-GRB080319B-was covered from rise till fall with high temporal resolution. Here we discuss these data, acquired with TORTORA fast wide-field monitoring optical camera, as well as results of its analysis. The camera observed the position of Naked-Eye Burst, GRB080318B, before, during and after the trigger. It detected the fast rise of optical emission, which reached the peak of V 5.3 at the eighteenth second, had a complex evolution till T+43s and monotonously faded then. The brightest part of the light curve contains two 15-20 s segments with different fluxes, each having two clearly-seen peaks of 5-8 s duration; all four peaks look quasi-periodic with separation of 9 s. There is no clear evidence of any sub-second variability. However, there are signs of quasi-periodic variability on 1s time scale at around the last peak (T+40 till T+50). The general properties of the optical light curve and its variability time scales look similar to the gamma one, but there is no clear correlation between them. This raises serious problems in interpretation of mechanisms generating such variability.

  19. IMAGING DIAGNOSIS OF THORACOLUMBAR BURST FRACTURES

    Institute of Scientific and Technical Information of China (English)

    Li-yang Dai

    2004-01-01

    Objective To review imaging use in the diagnosis ofthoracolumbar burst fractures and to determine the diagnostic value of different imaging methods.Methods One hundred and fourteen patients with 120 thoracolumbar burst fractures were retrospectively reviewed. Plain radiographs were available in all cases; CT scans and MRI were obtained in 96 and 74 cases, respectively.Results A total of 27 burst fractures were misdiagnosed as other types of fractures on radiographs alone, and accounted for 22.5% of all fractures. The results indicated that plain radiographs often fail to delineate the pathological features of thoracolumbar burst fractures, leading to delay in diagnosis.Conclusion In regard to thoracolumbar injury diagnosis, burst fractures should be differentiated from compression fractures. CT should be routinely indicated and MRI examination, when necessary, may be simultaneously considered.

  20. Bright 30 THz Impulsive Solar Bursts

    CERN Document Server

    Kaufmann, P; Marcon, R; Kudaka, A S; Cabezas, D P; Cassiano, M M; Francile, C; Fernandes, L O T; Ramirez, R F Hidalgo; Luoni, M; Marun, A; Pereyra, P; de Souza, R V

    2015-01-01

    Impulsive 30 THz continuum bursts have been recently observed in solar flares, utilizing small telescopes with a unique and relatively simple optical setup concept. The most intense burst was observed together with a GOES X2 class event on October 27, 2014, also detected at two sub-THz frequencies, RHESSI X-rays and SDO/HMI and EUV. It exhibits strikingly good correlation in time and in space with white light flare emission. It is likely that this association may prove to be very common. All three 30 THz events recently observed exhibited intense fluxes in the range of 104 solar flux units, considerably larger than those measured for the same events at microwave and sub-mm wavelengths. The 30 THz burst emission might be part of the same spectral burst component found at sub-THz frequencies. The 30 THz solar bursts open a promising new window for the study of flares at their origin

  1. Microsecond flares in gamma-ray bursts

    Science.gov (United States)

    Schaefer, Bradley E.; Cohen, Justin; Teegarden, Bonnard J.; Cline, Thomas L.; Fishman, Gerald J.; Meegan, Charles A.; Wilson, Robert B.; Paciesas, William S.; Pendleton, Geoffrey N.; Matteson, James L.

    1993-01-01

    It has been suggested that gamma-ray burst light curves may consist of many superposed flares with a duration shorter than 30/microsec. If true, the implications for the interpretation of burst data are enormous. With the launch of the Compton Gamma-Ray Observatory, four predictions of Mitrofanov's (1989) suggestion can be tested. Our results which contradict this suggestion are (1) the photon arrival times are not correlated between independent detectors, (2) the spectral hardness and intensity does not depend on the detector area, (3) the bursts seen by detectors which measure photon positions do not see microsecond flares, and (4) burst positions deduced from detectors with different projected areas are close to the positions deduced from time-of-flight differences between separated spacecraft. We conclude, therefore, that gamma-ray bursts are not composed of microsecond flares.

  2. FRBCAT: The Fast Radio Burst Catalogue

    Science.gov (United States)

    Petroff, E.; Barr, E. D.; Jameson, A.; Keane, E. F.; Bailes, M.; Kramer, M.; Morello, V.; Tabbara, D.; van Straten, W.

    2016-09-01

    Here, we present a catalogue of known Fast Radio Burst sources in the form of an online catalogue, FRBCAT. The catalogue includes information about the instrumentation used for the observations for each detected burst, the measured quantities from each observation, and model-dependent quantities derived from observed quantities. To aid in consistent comparisons of burst properties such as width and signal-to-noise ratios, we have re-processed all the bursts for which we have access to the raw data, with software which we make available. The originally derived properties are also listed for comparison. The catalogue is hosted online as a Mysql database which can also be downloaded in tabular or plain text format for off-line use. This database will be maintained for use by the community for studies of the Fast Radio Burst population as it grows.

  3. Bursting neurons and ultrasound avoidance in crickets.

    Science.gov (United States)

    Marsat, Gary; Pollack, Gerald S

    2012-01-01

    Decision making in invertebrates often relies on simple neural circuits composed of only a few identified neurons. The relative simplicity of these circuits makes it possible to identify the key computation and neural properties underlying decisions. In this review, we summarize recent research on the neural basis of ultrasound avoidance in crickets, a response that allows escape from echolocating bats. The key neural property shaping behavioral output is high-frequency bursting of an identified interneuron, AN2, which carries information about ultrasound stimuli from receptor neurons to the brain. AN2's spike train consists of clusters of spikes - bursts - that may be interspersed with isolated, non-burst spikes. AN2 firing is necessary and sufficient to trigger avoidance steering but only high-rate firing, such as occurs in bursts, evokes this response. AN2 bursts are therefore at the core of the computation involved in deciding whether or not to steer away from ultrasound. Bursts in AN2 are triggered by synaptic input from nearly synchronous bursts in ultrasound receptors. Thus the population response at the very first stage of sensory processing - the auditory receptor - already differentiates the features of the stimulus that will trigger a behavioral response from those that will not. Adaptation, both intrinsic to AN2 and within ultrasound receptors, scales the burst-generating features according to the stimulus statistics, thus filtering out background noise and ensuring that bursts occur selectively in response to salient peaks in ultrasound intensity. Furthermore AN2's sensitivity to ultrasound varies adaptively with predation pressure, through both developmental and evolutionary mechanisms. We discuss how this key relationship between bursting and the triggering of avoidance behavior is also observed in other invertebrate systems such as the avoidance of looming visual stimuli in locusts or heat avoidance in beetles.

  4. Quasi-periodic Oscillations and Broadband Variability in Short Magnetar Bursts

    Science.gov (United States)

    Huppenkothen, Daniela; Watts, Anna L.; Uttley, Phil; van der Horst, Alexander J.; van der Klis, Michiel; Kouveliotou, Chryssa; Göǧüş, Ersin; Granot, Jonathan; Vaughan, Simon; Finger, Mark H.

    2013-05-01

    The discovery of quasi-periodic oscillations (QPOs) in magnetar giant flares has opened up prospects for neutron star asteroseismology. However, with only three giant flares ever recorded, and only two with data of sufficient quality to search for QPOs, such analysis is seriously data limited. We set out a procedure for doing QPO searches in the far more numerous, short, less energetic magnetar bursts. The short, transient nature of these bursts requires the implementation of sophisticated statistical techniques to make reliable inferences. Using Bayesian statistics, we model the periodogram as a combination of red noise at low frequencies and white noise at high frequencies, which we show is a conservative approach to the problem. We use empirical models to make inferences about the potential signature of periodic and QPOs at these frequencies. We compare our method with previously used techniques and find that although it is on the whole more conservative, it is also more reliable in ruling out false positives. We illustrate our Bayesian method by applying it to a sample of 27 bursts from the magnetar SGR J0501+4516 observed by the Fermi Gamma-ray Burst Monitor, and we find no evidence for the presence of QPOs in any of the bursts in the unbinned spectra, but do find a candidate detection in the binned spectra of one burst. However, whether this signal is due to a genuine quasi-periodic process, or can be attributed to unmodeled effects in the noise is at this point a matter of interpretation.

  5. QUASI-PERIODIC OSCILLATIONS AND BROADBAND VARIABILITY IN SHORT MAGNETAR BURSTS

    Energy Technology Data Exchange (ETDEWEB)

    Huppenkothen, Daniela; Watts, Anna L.; Uttley, Phil; Van der Horst, Alexander J.; Van der Klis, Michiel [Astronomical Institute ' ' Anton Pannekoek' ' , University of Amsterdam, Postbus 94249, 1090-GE Amsterdam (Netherlands); Kouveliotou, Chryssa [Office of Science and Technology, ZP12, NASA Marshall Space Flight Center, Huntsville, AL 35812 (United States); Goegues, Ersin [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Granot, Jonathan [The Open University of Israel, 1 University Road, P.O. Box 808, Ra' anana 43537 (Israel); Vaughan, Simon [X-Ray and Observational Astronomy Group, University of Leicester, Leicester LE1 7RH (United Kingdom); Finger, Mark H., E-mail: D.Huppenkothen@uva.nl [Universities Space Research Association, Huntsville, AL 35805 (United States)

    2013-05-01

    The discovery of quasi-periodic oscillations (QPOs) in magnetar giant flares has opened up prospects for neutron star asteroseismology. However, with only three giant flares ever recorded, and only two with data of sufficient quality to search for QPOs, such analysis is seriously data limited. We set out a procedure for doing QPO searches in the far more numerous, short, less energetic magnetar bursts. The short, transient nature of these bursts requires the implementation of sophisticated statistical techniques to make reliable inferences. Using Bayesian statistics, we model the periodogram as a combination of red noise at low frequencies and white noise at high frequencies, which we show is a conservative approach to the problem. We use empirical models to make inferences about the potential signature of periodic and QPOs at these frequencies. We compare our method with previously used techniques and find that although it is on the whole more conservative, it is also more reliable in ruling out false positives. We illustrate our Bayesian method by applying it to a sample of 27 bursts from the magnetar SGR J0501+4516 observed by the Fermi Gamma-ray Burst Monitor, and we find no evidence for the presence of QPOs in any of the bursts in the unbinned spectra, but do find a candidate detection in the binned spectra of one burst. However, whether this signal is due to a genuine quasi-periodic process, or can be attributed to unmodeled effects in the noise is at this point a matter of interpretation.

  6. Time Lags between the 22 and 37 GHz Bursts of 48 Radio-loud AGNs

    Institute of Scientific and Technical Information of China (English)

    Wen-Guo Deng; Jin-Ming Bai; Li Zhang; Xian Yang

    2008-01-01

    Based on the light curves at 22 and 37 GHz from the Metsahovi monitoring pro-gram, we investigate the time lags between the two radio bands for 48 radio-loud AGNs. DCF and ZDCF analyses are applied to the data. Our results show that there is a strong correlation between the two radio frequencies for all the sources, with the variations in the light curvesat 37 GHz leading the ones at 22 GHz in general. There is no obvious differences between different sub-class AGNs as regards the time lag. In two sources, it was found that the bursts at the lower frequency lead the ones at the higher frequency. One possible explanation is that electron acceleration dominates the light curve until the radiation reaches the maximum. Some sources, such as 3C 273, 3C 279, 3C 345 and 3C 454.3, have good enough data, so we can calculate their lags burst-by-burst. Our calculations show that different outbursts have dif- ferent lags. Some bursts have positive lags, most of bursts have no clear lags, and a few have negative lags. This result means that different bursts are triggered by different mechanisms, and the interpretation for the result involves both an intrinsic and a geometric mechanism. The positive lags are well consistent with the shock model, and we use these lags to calculate the typical magnetic field strength of the radiating region.

  7. Spatiotemporal chaos from bursting dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Berenstein, Igal; De Decker, Yannick [Nonlinear Physical Chemistry Unit and Interdisciplinary Center for Nonlinear Phenomena and Complex Systems (CENOLI), Faculté des Sciences, Université libre de Bruxelles (ULB), Campus Plaine, C.P. 231, B-1050 Brussels (Belgium)

    2015-08-14

    In this paper, we study the emergence of spatiotemporal chaos from mixed-mode oscillations, by using an extended Oregonator model. We show that bursting dynamics consisting of fast/slow mixed mode oscillations along a single attractor can lead to spatiotemporal chaotic dynamics, although the spatially homogeneous solution is itself non-chaotic. This behavior is observed far from the Hopf bifurcation and takes the form of a spatiotemporal intermittency where the system locally alternates between the fast and the slow phases of the mixed mode oscillations. We expect this form of spatiotemporal chaos to be generic for models in which one or several slow variables are coupled to activator-inhibitor type of oscillators.

  8. Comparison of WATCH and IPN Locations of Gamma-Ray Bursts

    DEFF Research Database (Denmark)

    Hurley, K.; Lund, Niels; Brandt, Søren;

    1994-01-01

    The WATCH all sky monitors aboard the Granat and EURECA spacecraft have the capability of independently localizing gamma‐ray bursts to error circles whose 3 sigma radii are 1 degree or less. These are the most accurate single‐experiment localizations currently achievable. In those cases where bot...

  9. AIRSLUG: A fortran program for the computation of type curves to estimate transmissivity and storativity from prematurely terminated air-pressurized slug tests

    Science.gov (United States)

    Greene, E.A.; Shapiro, A.M.

    1998-01-01

    The Fortran code AIRSLUG can be used to generate the type curves needed to analyze the recovery data from prematurely terminated air-pressurized slug tests. These type curves, when used with a graphical software package, enable the engineer or scientist to analyze field tests to estimate transmissivity and storativity. Prematurely terminating the slug test can significantly reduce the overall time needed to conduct the test, especially at low-permeability sites, thus saving time and money.The Fortran code AIRSLUG can be used to generate the type curves needed to analyze the recovery data from prematurely terminated air-pressurized slug tests. These type curves, when used with a graphical software package, enable the engineer or scientist to analyze field tests to estimate transmissivity and storativity. Prematurely terminating the slug test can significantly reduce the overall time needed to conduct the test, especially at low-permeability sites, thus saving time and money.

  10. Observing a Burst with Sunglasses

    Science.gov (United States)

    2003-11-01

    Unique Five-Week VLT Study of the Polarisation of a Gamma-Ray Burst Afterglow "Gamma-ray bursts (GRBs)" are certainly amongst the most dramatic events known in astrophysics. These short flashes of energetic gamma-rays, first detected in the late 1960's by military satellites, last from less than one second to several minutes. GRBs have been found to be situated at extremely large ("cosmological") distances. The energy released in a few seconds during such an event is larger than that of the Sun during its entire lifetime of more than 10,000 million years. The GRBs are indeed the most powerful events since the Big Bang known in the Universe, cf. ESO PR 08/99 and ESO PR 20/00. During the past years circumstantial evidence has mounted that GRBs signal the collapse of extremely massive stars, the so-called hypernovae. This was finally demonstrated some months ago when astronomers, using the FORS instrument on ESO's Very Large Telescope (VLT), documented in unprecedented detail the changes in the spectrum of the light source ("the optical afterglow") of the gamma-ray burst GRB 030329 (cf. ESO PR 16/03). A conclusive and direct link between cosmological gamma-ray bursts and explosions of very massive stars was provided on this occasion. Gamma-Ray Burst GRB 030329 was discovered on March 29, 2003 by NASA's High Energy Transient Explorer spacecraft. Follow-up observations with the UVES spectrograph at the 8.2-m VLT KUEYEN telescope at the Paranal Observatory (Chile) showed the burst to have a redshift of 0.1685 [1]. This corresponds to a distance of about 2,650 million light-years, making GRB 030329 the second-nearest long-duration GRB ever detected. The proximity of GRB 030329 resulted in very bright afterglow emission, permitting the most extensive follow-up observations of any afterglow to date. A team of astronomers [2] led by Jochen Greiner of the Max-Planck-Institut für extraterrestrische Physik (Germany) decided to make use of this unique opportunity to study the

  11. A numerical study of rock burst development and strain energy release

    Institute of Scientific and Technical Information of China (English)

    Wang Li; Lu ZhongLiang; Gao Qian

    2012-01-01

    We consider rock burst to be a dynamic disaster similar to earthquakes,rapid land sliding,or coal mine gas dynamic disasters.Multi-scale mechanical principles imply the same mechanism of damage evolution proceeds the catastrophe.Damage may occur at various scales from a meso-scopic scale to a macroscopic,or engineering scale.Rock burst is a catastrophe at the scale of the engineering structure,such as a tunnel cross section or the work face of a long wall mine.It results from dynamic fracture of the structure where microscopic damage nucleates,expands,and finally propagates into a macroscopic sized fracture band.Rock burst must,therefore,undergo a relatively long development,or gestation,time before its final appearance.In this paper,a study of rock burst within a deeply buried tunnel by numerical methods is described.The results show that during rock burst gestation the distributed microscopic damage in the rock surrounding the tunnel localizes,intersects,and then evolves into a set of concentrated “V” shaped damage bands.These concentrated damage bands propagate in the direction of maximum shear as shearing slide bands take shape.Rock burst happens within the wedge separated by the shear bands from the native tunnel rock.An analysis of the wedge fracture shows that the unloading effects result in rock burst and rapid release of the strain energy.The implications for rock burst prediction in tunnels are that: (1)rock burst develops in the upper arch corners of in the tunnel cross section prior to developing in other zones,so good attention must be paid there; (2) all monitoring,prevention,and treatment of rock burst should be done during the gestation phase; (3) the shear bands contain abundant information concerning the physics and mechanics of the process and they are the foundation of physical and mechanical monitoring of acoustic emission,micro seismic events,stress,and the like.Thus a special study of the shearing mechanism is required.

  12. The Case of the Disappearing Spindle Burst

    Directory of Open Access Journals (Sweden)

    Alexandre Tiriac

    2016-01-01

    Full Text Available Sleep spindles are brief cortical oscillations at 10–15 Hz that occur predominantly during non-REM (quiet sleep in adult mammals and are thought to contribute to learning and memory. Spindle bursts are phenomenologically similar to sleep spindles, but they occur predominantly in early infancy and are triggered by peripheral sensory activity (e.g., by retinal waves; accordingly, spindle bursts are thought to organize neural networks in the developing brain and establish functional links with the sensory periphery. Whereas the spontaneous retinal waves that trigger spindle bursts in visual cortex are a transient feature of early development, the myoclonic twitches that drive spindle bursts in sensorimotor cortex persist into adulthood. Moreover, twitches—and their associated spindle bursts—occur exclusively during REM (active sleep. Curiously, despite the persistence of twitching into adulthood, twitch-related spindle bursts have not been reported in adult sensorimotor cortex. This raises the question of whether such spindle burst activity does not occur in adulthood or, alternatively, occurs but has yet to be discovered. If twitch-related spindle bursts do occur in adults, they could contribute to the calibration, maintenance, and repair of sensorimotor systems.

  13. Bursting neurons and ultrasound avoidance in crickets

    Directory of Open Access Journals (Sweden)

    Gary eMarsat

    2012-07-01

    Full Text Available Decision making in invertebrates often relies on simple neural circuits composed of only a few identified neurons. The relative simplicity of these circuits makes it possible to identify the key computation and neural properties underlying decisions. In this review, we summarize recent research on the neural basis of ultrasound avoidance in crickets, a response that allows escape from echolocating bats. The key neural property shaping behavioral output is high-frequency bursting of an identified interneuron, AN2, which carries information about ultrasound stimuli from receptor neurons to the brain. AN2's spike train consists of clusters of spikes –bursts– that may be interspersed with isolated, non-burst spikes. AN2 firing is necessary and sufficient to trigger avoidance steering but only high-rate firing, such as occurs in bursts, evokes this response. AN2 bursts are therefore at the core of the computation involved in deciding whether or not to steer away from ultrasound. Bursts in AN2 are triggered by synaptic input from nearly synchronous bursts in ultrasound receptors. Thus the population response at the very first stage of sensory processing –the auditory receptor- already differentiates the features of the stimulus that will trigger a behavioral response from those that will not. Adaptation, both intrinsic to AN2 and within ultrasound receptors, scales the burst-generating features according to the stimulus statistics, thus filtering out background noise and ensuring that bursts occur selectively in response to salient peaks in ultrasound intensity. Furthermore AN2’s sensitivity to ultrasound varies adaptively with predation pressure, through both developmental and evolutionary mechanisms. We discuss how this key relationship between bursting and the triggering of avoidance behavior is also observed in other invertebrate systems such as the avoidance of looming visual stimuli in locusts or heat avoidance in beetles.

  14. Load carrying capacity of the reactor pressure vessel head in case of a molten fuel slug impact caused by a steam explosion. Discussion of different solution methods

    International Nuclear Information System (INIS)

    Extensive research work is being carried out at KfK on slug impact on the reactor pressure vessel head. Important considerations on and possible solutions to this problem are discussed. In order to separate the work from the parallel investigations of steam explosions, the tasks were modified. The speeds of impinging slug are determined, which the reactor pressure vessel head can reliably withstand. (orig./HP)

  15. Gamma-Ray Bursts: Jets and Energetics

    CERN Document Server

    Frail, D A

    2003-01-01

    The relativistic outflows from gamma-ray bursts are now thought to be narrowly collimated into jets. After correcting for this jet geometry there is a remarkable constancy of both the energy radiated by the burst and the kinetic energy carried by the outflow. Gamma-ray bursts are still the most luminous explosions in the Universe, but they release energies that are comparable to supernovae. The diversity of cosmic explosions appears to be governed by the fraction of energy that is coupled to ultra-relativistic ejecta.

  16. EXIST's Gamma-Ray Burst Sensitivity

    OpenAIRE

    Band, D. L.; Grindlay, J. E.; Hong, J.; Fishman, G.; Hartmann, D. H.; Garson III, A.; Krawczynski, H.; Barthelmy, S.; Gehrels, N.; Skinner, G.

    2007-01-01

    We use semi-analytic techniques to evaluate the burst sensitivity of designs for the EXIST hard X-ray survey mission. Applying these techniques to the mission design proposed for the Beyond Einstein program, we find that with its very large field-of-view and faint gamma-ray burst detection threshold, EXIST will detect and localize approximately two bursts per day, a large fraction of which may be at high redshift. We estimate that EXIST's maximum sensitivity will be ~4 times greater than that...

  17. The Arecibo Fast Radio Burst: Dense Circum-burst Medium

    CERN Document Server

    Kulkarni, S R; Neill, J D

    2015-01-01

    The nature of fast radio bursts (FRB) has been extensively debated. Here we investigate FRB121102, detected at Arecibo telescope and remarkable for its unusually large spectral index. After extensive study we conclude that the spectral index is caused by a nebula with free-free absorption. We find that putative nebula must lie beyond the Milky Way. We conclude that FRBs are of extra-galactic origin and that they arise in dense star-forming regions. The challenge with extra-galactic models is the the high volumetric rate of FRBs. This high rate allows us to eliminate all models of catastrophic stellar deaths. Hyper-giant flares from young magnetars emerge as the most likely progenitors. Some of the consequences are: (i) Intergalactic FRB models can be safely ignored. (ii) The rich ISM environment of young magnetars can result in significant contribution to DM, Rotation Measure (RM) and in some cases to significant free-free optical depth. (iii) The star-forming regions in the host galaxies can contribute signi...

  18. Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity123

    Science.gov (United States)

    Ferrari-Amorotti, Giovanna; Chiodoni, Claudia; Shen, Fei; Cattelani, Sara; Soliera, Angela Rachele; Manzotti, Gloria; Grisendi, Giulia; Dominici, Massimo; Rivasi, Francesco; Colombo, Mario Paolo; Fatatis, Alessandro; Calabretta, Bruno

    2014-01-01

    Most triple-negative breast cancers (TNBCs) exhibit gene expression patterns associated with epithelial-to-mesenchymal transition (EMT), a feature that correlates with a propensity for metastatic spread. Overexpression of the EMT regulator Slug is detected in basal and mesenchymal-type TNBCs and is associated with reduced E-cadherin expression and aggressive disease. The effects of Slug depend, in part, on the interaction of its N-terminal SNAG repressor domain with the chromatin-modifying protein lysine demethylase 1 (LSD1); thus, we investigated whether tranylcypromine [also known as trans-2-phenylcyclopropylamine hydrochloride (PCPA) or Parnate], an inhibitor of LSD1 that blocks its interaction with Slug, suppresses the migration, invasion, and metastatic spread of TNBC cell lines. We show here that PCPA treatment induces the expression of E-cadherin and other epithelial markers and markedly suppresses migration and invasion of TNBC cell lines MDA-MB-231 and BT-549. These effects were phenocopied by Slug or LSD1 silencing. In two models of orthotopic breast cancer, PCPA treatment reduced local tumor growth and the number of lung metastases. In mice injected directly in the blood circulation with MDA-MB-231 cells, PCPA treatment or Slug silencing markedly inhibited bone metastases but had no effect on lung infiltration. Thus, blocking Slug activity may suppress the metastatic spread of TNBC and, perhaps, specifically inhibit homing/colonization to the bone. PMID:25499218

  19. Assessment of Mass Transfer Coefficients in Coalescing Slug Flow in Vertical Pipes and Applications to Tubular Airlift Membrane Bioreactors

    DEFF Research Database (Denmark)

    Ratkovich, Nicolas Rios; Berube, P.R.; Nopens, I.

    2011-01-01

    ) cannot be applied directly. As an alternative, in this work, a multidisciplinary approach was selected, by exploiting dimensionless analysis using the Sherwood number. Mass transfer coefficients were measured at various superficial velocities of gas and liquid flow in a tubular system. Due......One of the operational challenges associated with membrane bioreactors (MBRs) is the fouling of the membranes. In tubular side-stream MBRs, fouling reduction can be achieved through controlling the hydrodynamics of the two-phase slug flow near the membrane surface. The two-phase slug flow induces...... higher shear stresses near the membrane surface, which generate high mass transfer coefficients from the surface to the bulk region. However, measuring the mass transfer coefficient is difficult in complex heterogeneous mixtures like activated sludge and existing techniques (e.g. electrochemical methods...

  20. VizieR Online Data Catalog: Slug analysis of star clusters in NGC 628 & 7793 (Krumholz+, 2015)

    Science.gov (United States)

    Krumholz, M. R.; Adamo, A.; Fumagalli, M.; Wofford, A.; Calzetti, D.; Lee, J. C.; Whitmore, B. C.; Bright, S. N.; Grasha, K.; Gouliermis, D. A.; Kim, H.; Nair, P.; Ryon, J. E.; Smith, L. J.; Thilker, D.; Ubeda, L.; Zackrisson, E.

    2016-02-01

    In this paper we use slug, the Stochastically Lighting Up Galaxies code (da Silva et al. 2012ApJ...745..145D, 2014MNRAS.444.3275D; Krumholz et al. 2015MNRAS.452.1447K), and its post-processing tool for analysis of star cluster properties, cluster_slug, to analyze an initial sample of clusters from the LEGUS (Calzetti et al. 2015AJ....149...51C). A description of the steps required to produce final cluster catalogs of the Legacy Extragalactic UV Survey (LEGUS) targets can be found in Calzetti et al. (2015AJ....149...51C), and in A. Adamo et al. (2015, in preparation). LEGUS is an HST Cycle 21 Treasury program that is imaging 50 nearby galaxies in five broadbands with the WFC3/UVIS, from the NUV to the I band. (1 data file).

  1. ESTIMATE OF BURSTING PRESSURE OF MILD STEEL PRESSURE VESSEL AND PRESENTATION OF BURSTING FORMULA

    Institute of Scientific and Technical Information of China (English)

    ZHENG Chuanxiang

    2006-01-01

    In order to get more precise bursting pressure formula of mild steel, hundreds of bursting experiments of mild steel pressure vessels such as Q235(Gr.D) and 20R(1020) are done. Based on statistical data of bursting pressure and modification of Faupel formula, a more precise modified formula is given out according to the experimental data. It is proved to be more accurate after examining other bursting pressure value presented in many references. This bursting formula is very accurate in these experiments using pressure vessels with different diameter and shell thickness.Obviously, this modified bursting formula can be used in mild steel pressure vessels with different diameter and thickness of shell.

  2. Closed-analytical mixing model describing the slug transport from the inlet nozzle to the reactor core in PWR

    International Nuclear Information System (INIS)

    A closed-analytical model describing the slug transport from the inlet nozzle to the reactor core is presented. For the time being, it is applicable only to steady flow and probably only for symmetrical flow conditions. Using an analytical solution of the 1D diffusion equation for linear time-variable diffusion coefficients found by the authors, mixing in a transient flow may be modelled as well. (orig.)

  3. Ecoulements Diphasiques à poches en conduite horizontale Horizontal Slug Flow in Pipes

    Directory of Open Access Journals (Sweden)

    Ferré D.

    2006-11-01

    Full Text Available Cette étude a eu pour objectif de préciser certains phénomènes caractéristiques des écoulements diphasiques rencontrés lors du transport par oléoducs des bruts pétroliers à teneur en gaz faible ou moyenne. Des expériences ont été réalisées à basse pression sur une boucle diphasique eau-air de diamètre 0,045 m et de longueur 50 m. Les mesures de présence de phase locale et de pression effectuées à la paroi pour des vitesses débitantes du liquide et du gaz variant respectivement entre 0,5 et 2 m/s et 0,3 et 10 m/s, ont permis d'accéder aux principales grandeurs cinématiques des écoulements à poches. A l'aide des méthodes classiques de l'analyse statistique, on a caractérisé l'aspect aléatoire de ces écoulements, la longueur d'établissement des régimes, la coalescence des poches. Enfin, en appliquant les équations diphasiques générales intégrées, on a précisé les ordres de grandeur et les tendances d'évolution de quelques lois phénoménologiques, pour en déduire une loi approchée du gradient de pression. The aim of this study is to describe various characteristic phenomena of two-phase flow encountered in the pipelining of crude oil with a love or medium gas content. Love-pressure experiments were performed with a two-phase water-air loop 0.045 mm in diameter and 50 m long. Measurements at the wall of local phase and pressure for liquid and gas flowrates varying between 0.5 and 2 m/s and 0.3 and 10 m/s revealed the leading kinematic magnitudes of slug flow. Conventional statistical-analysis methods were used ta characterize the random aspect of such flows, the length required for flow conditions ta be established and thé coalescence of slugs. General integrated two-phase équations were used to determine the orders of magnitude and variation tendencies of various phenomenological laves so as to deduce on approximate lave for the pressure gradient.

  4. THE FERMI GBM GAMMA-RAY BURST CATALOG: THE FIRST TWO YEARS

    Energy Technology Data Exchange (ETDEWEB)

    Paciesas, William S.; Bhat, P. N.; Briggs, Michael S.; Burgess, J. Michael; Chaplin, Vandiver; Connaughton, Valerie; Goldstein, Adam; Guiriec, Sylvain [Center for Space Plasma and Aeronomic Research, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Meegan, Charles A.; Van der Horst, Alexander J. [Universities Space Research Association, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Von Kienlin, Andreas; Diehl, Roland; Foley, Suzanne; Greiner, Jochen; Gruber, David [Max-Planck-Institut fuer extraterrestrische Physik, Giessenbachstrasse 1, 85748 Garching (Germany); Bissaldi, Elisabetta [Institute of Astro and Particle Physics, University Innsbruck, Technikerstrasse 25, 6176 Innsbruck (Austria); Fishman, Gerald J. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Fitzpatrick, Gerard [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Gibby, Melissa; Giles, Misty [Jacobs Technology, Inc., 1525 Perimeter Pkwy NW, Huntsville, AL 35806 (United States); and others

    2012-03-01

    The Fermi Gamma-ray Burst Monitor (GBM) is designed to enhance the scientific return from Fermi in studying gamma-ray bursts (GRBs). In its first two years of operation GBM triggered on 491 GRBs. We summarize the criteria used for triggering and quantify the general characteristics of the triggered GRBs, including their locations, durations, peak flux, and fluence. This catalog is an official product of the Fermi GBM science team, and the data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center.

  5. SROSS C-2 Detections of Gamma Ray Bursts and the SGR 1627-41

    Indian Academy of Sciences (India)

    S. Sinha; P. Sreekumar; K. Kasturirangan

    2002-03-01

    The GRB monitor (GRBM) on board the Indian SROSS C-2 satellite has detected 53 classical gamma ray bursts since its launch in May, 1994 till its re-entry in July, 2001. For a subset of 26 events, locations were obtained from simultaneous observations by other gamma-ray detectors in space. The sky distribution of these 26 SROSS C-2 bursts is consistent with isotropy. The distribution of event durations shows evidence for bimodality. There is an evidence for a moderate hardness ratio-intensity (HIC) correlation in the data. The SROSS C-2 GRBM has also detected three episodes of emission from the SGR 1627-41.

  6. The Fermi GBM Gamma-Ray Burst Catalog: The First Two Years

    CERN Document Server

    Paciesas, William S; von Kienlin, Andreas; Bhat, P N; Bissaldi, Elisabetta; Briggs, Michael S; Burgess, J Michael; Chaplin, Vandiver; Connaughton, Valerie; Diehl, Roland; Fishman, Gerald J; Fitzpatrick, Gerard; Foley, Suzanne; Gibby, Melissa; Giles, Misty; Goldstein, Adam; Greiner, Jochen; Gruber, David; Guiriec, Sylvain; van der Horst, Alexander J; Kippen, R Marc; Kouveliotou, Chryssa; Lichti, Giselher; Lin, Lin; McBreen, Sheila; Preece, Robert D; Rau, Arne; Tierney, Dave; Wilson-Hodge, Colleen

    2012-01-01

    The Fermi Gamma-ray Burst Monitor (GBM) is designed to enhance the scientific return from Fermi in studying gamma-ray bursts (GRBs). In its first two years of operation GBM triggered on 491 GRBs. We summarize the criteria used for triggering and quantify the general characteristics of the triggered GRBs, including their locations, durations, peak flux, and fluence. This catalog is an official product of the Fermi GBM science team, and the data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center (HEASARC).

  7. Opisthobranchia (Mollusca, Gastropoda) - more than just slimy slugs. Shell reduction and its implications on defence and foraging.

    Science.gov (United States)

    Wägele, Heike; Klussmann-Kolb, Annette

    2005-02-16

    BACKGROUND: In general shell-less slugs are considered to be slimy animals with a rather dull appearance and a pest to garden plants. But marine slugs usually are beautifully coloured animals belonging to the less-known Opisthobranchia. They are characterized by a large array of interesting biological phenomena, usually related to foraging and/or defence. In this paper our knowledge of shell reduction, correlated with the evolution of different defensive and foraging strategies is reviewed, and new results on histology of different glandular systems are included. RESULTS: Based on a phylogeny obtained by morphological and histological data, the parallel reduction of the shell within the different groups is outlined. Major food sources are given and glandular structures are described as possible defensive structures in the external epithelia, and as internal glands. CONCLUSION: According to phylogenetic analyses, the reduction of the shell correlates with the evolution of defensive strategies. Many different kinds of defence structures, like cleptocnides, mantle dermal formations (MDFs), and acid glands, are only present in shell-less slugs. In several cases, it is not clear whether the defensive devices were a prerequisite for the reduction of the shell, or reduction occurred before. Reduction of the shell and acquisition of different defensive structures had an implication on exploration of new food sources and therefore likely enhanced adaptive radiation of several groups. PMID:15715915

  8. Opisthobranchia (Mollusca, Gastropoda – more than just slimy slugs. Shell reduction and its implications on defence and foraging

    Directory of Open Access Journals (Sweden)

    Wägele Heike

    2005-02-01

    Full Text Available Abstract Background In general shell-less slugs are considered to be slimy animals with a rather dull appearance and a pest to garden plants. But marine slugs usually are beautifully coloured animals belonging to the less-known Opisthobranchia. They are characterized by a large array of interesting biological phenomena, usually related to foraging and/or defence. In this paper our knowledge of shell reduction, correlated with the evolution of different defensive and foraging strategies is reviewed, and new results on histology of different glandular systems are included. Results Based on a phylogeny obtained by morphological and histological data, the parallel reduction of the shell within the different groups is outlined. Major food sources are given and glandular structures are described as possible defensive structures in the external epithelia, and as internal glands. Conclusion According to phylogenetic analyses, the reduction of the shell correlates with the evolution of defensive strategies. Many different kinds of defence structures, like cleptocnides, mantle dermal formations (MDFs, and acid glands, are only present in shell-less slugs. In several cases, it is not clear whether the defensive devices were a prerequisite for the reduction of the shell, or reduction occurred before. Reduction of the shell and acquisition of different defensive structures had an implication on exploration of new food sources and therefore likely enhanced adaptive radiation of several groups.

  9. Binary tree-based fault location algorithm for optical burst switching network

    Institute of Scientific and Technical Information of China (English)

    WANG Ru-yan; LIU Dan; PENG Huan-jia; LV Ke-wei

    2009-01-01

    This paper proposes an effective method of fault location based on a binary tree for optical burst switching (OBS) network. To minimize the monitoring cost, we divide the network into several monitor domains by introducing monitoring-cycle algorithms. In order to generate an exclusive code, we modify the monitoring cycle algorithm when two nodes have the same code. Through the binary tree algorithm, a pre-computation of faults in the OBS network can be achieved. When a fault happens, we can locate it immediately and accurately. Examples have proved that the algorithm has general applicability.

  10. Long Burst Error Correcting Codes Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Long burst error mitigation is an enabling technology for the use of Ka band for high rate commercial and government users. Multiple NASA, government, and...

  11. Bursts of intermediate ions in atmospheric air

    Science.gov (United States)

    Hõrrak, U.; Salm, J.; Tammet, H.

    1998-06-01

    The mobility spectrum of air ions has been measured at Tahkuse Observatory in Estonia for several years. The average concentration of intermediate ions with mobilities of 0.05-0.5 cm2 V-1 s-1 in atmospheric air is about 50 cm-3. On the level of this low background, high concentration bursts of intermediate air ions occur occasionally. A burst can be followed by subsequent evolution of intermediate ions into larger ones. To explain the bursts of intermediate air ions, two hypotheses can be advanced: (1)A burst of neutral particles occurs due to homogeneous nucleation, and the particles are charged by the attachment of cluster ions. (2) The cluster ions grow by ion-induced nucleation in proper environmental conditions.

  12. CMEs and frequency cutoff of solar bursts

    Science.gov (United States)

    Stanislavsky, Al.; Konovalenko, Al.; Koval, Ar.; Volvach, Y.; Zarka, P.

    2016-05-01

    Radio observations of solar bursts with high-frequency cutoff by the radio telescope UTR-2 (near Kharkiv, Ukraine) at 8-33 MHz on 17-19 August 2012 are presented. Such cutoff may be attributed to the emergence of the burst sources behind limb of the Sun with respect to an observer on the Earth. The events are strongly associated with solar eruptions occurred in a new active region. Ray tracing simulations show that the CMEs play a constructive role for the behind-limb bursts to be detected in ground-based observations. Likely, due to tunnel-like cavities with low density in CMEs, the radio emission of behind-limb solar bursts can be directed towards the Earth.

  13. FRBCAT: The Fast Radio Burst Catalogue

    CERN Document Server

    Petroff, E; Jameson, A; Keane, E F; Bailes, M; Kramer, M; Morello, V; Tabbara, D; van Straten, W

    2016-01-01

    Here we present a catalogue of known Fast Radio Burst (FRB) sources in the form of an online catalogue, FRBCAT. The catalogue includes information about the instrumentation used for the observations for each detected burst, the measured quantities from each observation, and model-dependent quantities derived from observed quantities. To aid in consistent comparisons of burst properties such as width and signal-to-noise ratios we have reprocessed all the bursts for which we have access to the raw data, with software which we make available. The originally derived properties are also listed for comparison. The catalogue is hosted online as a MySQL database which can also be downloaded in tabular or plain text format for off-line use. This database will be maintained for use by the community for studies of the FRB population as it grows.

  14. Axion Stars and Fast Radio Bursts

    CERN Document Server

    Iwazaki, A

    2014-01-01

    We show that fast radio bursts arise from collisions between axion stars and neutron stars. The bursts are emitted in the atmosphere of the neutron stars. The observed frequencies of the bursts are given by the axion mass $m_a$ such as $m_a/2\\pi\\simeq 1.4\\,\\mbox{GHz}\\,\\big(m_a/(6\\times 10^{-6}\\mbox{eV})\\big)$. From the event rate $\\sim 10^{-3}$ per year in a galaxy, we can determine the mass $\\sim 10^{-11}M_{\\odot}$ of the axion stars. Using these values we can explain short durations ( $\\sim $ms ) and amount of radiation energies ( $\\sim 10^{43}$GeV ) of the bursts.

  15. Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU UP-1 Wells 299-W19-48, 699-30-66, and 699-36-70B

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.; Newcomer, Darrell R.

    2010-06-15

    This report presents test descriptions and analysis results for multiple, stress-level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) UP-1 wells: 299-W19-48 (C4300/Well K), 699-30-66 (C4298/Well R), and 699-36-70B (C4299/Well P). These wells are located within, adjacent to, and to the southeast of the Hanford Site 200-West Area. The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OU UP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.

  16. Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU ZP-1 Wells 299-W11-43, 299-W15-50, and 299-W18-16

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.; Newcomer, Darrell R.

    2010-06-21

    The following report presents test descriptions and analysis results for multiple, stress level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) ZP-1 wells: 299-W11-43 (C4694/Well H), 299-W15-50 (C4302/Well E), and 299-W18-16 (C4303/Well D). These wells are located within south-central region of the Hanford Site 200-West Area (Figure 1.1). The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OU ZP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.

  17. Design of assembly control algorithm based on burst-size feedback for optical burst switching network

    Institute of Scientific and Technical Information of China (English)

    Minglei Fu; Zichun Le

    2009-01-01

    A novel assembly control algorithm named burst-size feedback adaptive assembly period(BFAAP)is proposed.The major difference between BFAAP and other similar adaptive assembly algorithms is that the control curve of BFAAP is dynamically adjusted according to the feedback of outgoing burst size.BFAAP is compared with two typical algorithms fixed assembly period(FAP)aild min-burst length max assembly period(MBMAP)in simulation in terms of burst size distribution and assembly period.Moreover,the transmission control protocol(TCP)performance over BFAAP is also considered and simulated.

  18. Syudy of Token Generation for Burst Traffic Shaping in Optical Burst Switching Networks

    Institute of Scientific and Technical Information of China (English)

    Tang Wan; So Won-ho; Lu Ji-guang; Kim Young-chon

    2004-01-01

    Traffic shaping is one of important control operation to guarantee the Quality of Service (QoS) in optical burst switching (OBS) networks. The efficiency of traffic shaping is mainly determined by token generation method. In this paper, token generation methods of traffic shaping are evaluated by using three kinds of probability distribution, and are analyzed in terms of burst blocking probability, throughput and correlation by simulation. The simulation results show that the token generation methods decrease the burst correlation of Label Switched Paths (LSPs), and solve traffic congestion as well. The different burst arrival processes have small impact on the blocking probability for OBS networks.

  19. Optimal Codes for the Burst Erasure Channel

    Science.gov (United States)

    Hamkins, Jon

    2010-01-01

    Deep space communications over noisy channels lead to certain packets that are not decodable. These packets leave gaps, or bursts of erasures, in the data stream. Burst erasure correcting codes overcome this problem. These are forward erasure correcting codes that allow one to recover the missing gaps of data. Much of the recent work on this topic concentrated on Low-Density Parity-Check (LDPC) codes. These are more complicated to encode and decode than Single Parity Check (SPC) codes or Reed-Solomon (RS) codes, and so far have not been able to achieve the theoretical limit for burst erasure protection. A block interleaved maximum distance separable (MDS) code (e.g., an SPC or RS code) offers near-optimal burst erasure protection, in the sense that no other scheme of equal total transmission length and code rate could improve the guaranteed correctible burst erasure length by more than one symbol. The optimality does not depend on the length of the code, i.e., a short MDS code block interleaved to a given length would perform as well as a longer MDS code interleaved to the same overall length. As a result, this approach offers lower decoding complexity with better burst erasure protection compared to other recent designs for the burst erasure channel (e.g., LDPC codes). A limitation of the design is its lack of robustness to channels that have impairments other than burst erasures (e.g., additive white Gaussian noise), making its application best suited for correcting data erasures in layers above the physical layer. The efficiency of a burst erasure code is the length of its burst erasure correction capability divided by the theoretical upper limit on this length. The inefficiency is one minus the efficiency. The illustration compares the inefficiency of interleaved RS codes to Quasi-Cyclic (QC) LDPC codes, Euclidean Geometry (EG) LDPC codes, extended Irregular Repeat Accumulate (eIRA) codes, array codes, and random LDPC codes previously proposed for burst erasure

  20. Neutrinos from Gamma Ray Bursts

    CERN Document Server

    Mannheim, K

    2000-01-01

    The observed fluxes of cosmic rays and gamma rays are used to infer the maximum allowed high-energy neutrino flux allowed for Gamma Ray Bursts (GRBs), following Mannheim, Protheroe, and Rachen (2000). It is shown that if GRBs produce the ultrahigh-energy cosmic rays, they should contribute (a) at least 10% of the extragalactic gamma ray background between 3 MeV and 30 GeV, contrary to their observed energy flux which is only a minute fraction of this flux, and (b) a cumulative neutrino flux a factor of 20 below the AMANDA (Neutrino 2000) limit on isotropic neutrinos. This could have two implications, either GRBs do not produce the ultrahigh energy cosmic rays or that the GRBs are strongly beamed and emit most of their power at energies well above 100 GeV implausibly increasing the energy requirements, but consistent with the marginal detections of a few low-redshift GRBs by MILAGRITO, HEGRA-AIROBICC, and the Tibet-Array. All crucial measurements to test the models will be available in the next few years. Thes...

  1. Bursting the Taylor cone bubble

    Science.gov (United States)

    Pan, Zhao; Truscott, Tadd

    2014-11-01

    A soap bubble fixed on a surface and placed in an electric field will take on the shape of a cone rather than constant curvature (dome) when the electrical field is not present. The phenomenon was introduced by J. Zeleny (1917) and studied extensively by C.T. Wilson & G.I. Taylor (1925). We revisit the Taylor cone problem by studying the deformation and bursting of soap bubbles in a point charge electric field. A single bubble takes on the shape of a cone in the electric field and a high-speed camera equipped with a micro-lens is used to observe the unsteady dynamics at the tip. Rupture occurs as a very small piece of the tip is torn away from the bubble toward the point charge. Based on experiments, a theoretical model is developed that predicts when rupture should occur. This study may help in the design of foam-removal techniques in engineering and provide a better understanding of an electrified air-liquid interface.

  2. Gamma-ray Burst Cosmology

    CERN Document Server

    Wang, F Y; Liang, E W

    2015-01-01

    Gamma-ray bursts (GRBs) are the most luminous electromagnetic explosions in the Universe, which emit up to $8.8\\times10^{54}$ erg isotropic equivalent energy in the hard X-ray band. The high luminosity makes them detectable out to the largest distances yet explored in the Universe. GRBs, as bright beacons in the deep Universe, would be the ideal tool to probe the properties of high-redshift universe: including the cosmic expansion and dark energy, star formation rate, the reionization epoch and the metal enrichment history of the Universe. In this article, we review the luminosity correlations of GRBs, and implications for constraining the cosmological parameters and dark energy. Observations show that the progenitors of long GRBs are massive stars. So it is expected that long GRBs are tracers of star formation rate. We also review the high-redshift star formation rate derived from GRBs, and implications for the cosmic reionization history. The afterglows of GRBs generally have broken power-law spectra, so it...

  3. Gamma Ray Bursts as Neutrino Sources

    CERN Document Server

    Mészáros, P

    2015-01-01

    Gamma-ray burst sources appear to fulfill all the conditions for being efficient cosmic ray accelerators, and being extremely compact, are also expected to produce multi-GeV to PeV neutrinos. I review the basic model predictions for the expected neutrino fluxes in classical GRBs as well as in low luminosity and choked bursts, discussing the recent IceCube observational constraints and implications from the observed diffuse neutrino flux.

  4. Supernovae and gamma-ray bursts connection

    Science.gov (United States)

    Valle, Massimo Della

    2015-12-01

    I'll review the status of the Supernova/Gamma-Ray Burst connection. Several pieces of evidence suggest that long duration Gamma-ray Bursts are associated with bright SNe-Ic. However recent works suggest that GRBs might be produced in tight binary systems composed of a massive carbon-oxygen cores and a neutron star companion. Current estimates of the SN and GRB rates yield a ratio GRB/SNe-Ibc in the range ˜ 0.4% - 3%.

  5. Black Hole Lensing and Wave Bursts

    CERN Document Server

    Gogberashvili, Merab

    2016-01-01

    It is shown that close to a black hole horizon wave equations have real-valued exponentially time-dependent solutions and to investigate strong gravitational lensing we need to introduce an effective negative cosmological constant between the Schwarzschild and photon spheres. Then exponentially amplified reflected waves from this effective AdS space could explain properties of some gamma ray bursts, fast radio bursts and gravitational waves.

  6. Supernovae and gamma-ray bursts connection

    Energy Technology Data Exchange (ETDEWEB)

    Valle, Massimo Della [INAF-Napoli, Capodimonte Observatory, Salita Moiariello, 16, I-80131 Napoli (Italy); International Center for Relativistic Astrophysics Network, Piazzale della Repubblica 10, I-65122, Pescara (Italy)

    2015-12-17

    I’ll review the status of the Supernova/Gamma-Ray Burst connection. Several pieces of evidence suggest that long duration Gamma-ray Bursts are associated with bright SNe-Ic. However recent works suggest that GRBs might be produced in tight binary systems composed of a massive carbon-oxygen cores and a neutron star companion. Current estimates of the SN and GRB rates yield a ratio GRB/SNe-Ibc in the range ∼ 0.4% − 3%.

  7. Autaptic Connections Shift Network Excitability and Bursting

    OpenAIRE

    Wiles, Laura; Gu, Shi; Pasqualetti, Fabio; Bassett, Danielle S.; Meaney, David F.

    2016-01-01

    Network architecture forms a critical constraint on neuronal function. Here we examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal activity, we study how autaptic connections affect activity patterns, and evaluate if neuronal degree or controllability are significant factors that affect changes in bursting from these autaptic connections. We observed that adding increasing numbers of a...

  8. Cosmological parametrization of $\\gamma$ ray burst models

    CERN Document Server

    Linder, E V

    1996-01-01

    Using three parametrizations of the gamma ray burst count data comparison is made to cosmological source models. While simple models can fit and faint end slope constraints, the addition of a logarithmic count range variable describing the curvature of the counts shows that models with no evolution or evolution power law in redshift with index less than 10 fail to satisfy simultaneously all three descriptors of the burst data. The cosmological source density that would be required for a fit is illustrated.

  9. MIRAX sensitivity for Gamma Ray Bursts

    Science.gov (United States)

    Sacahui, J. R.; Penacchioni, A. V.; Braga, J.; Castro, M. A.; D'Amico, F.

    2016-03-01

    In this work we present the detection capability of the MIRAX (Monitor e Imageador de RAios-X) experiment for Gamma-Ray Bursts (GRBs). MIRAX is an X-ray astronomy mission designed to perform a wide band hard X-ray (10-200 keV) survey of the sky, especially in the Galactic plane. With a total detection area of 169 cm2, large field of view (FoV, 20 ° × 20 °), angular resolution of 1°45‧ and good spectral and time resolution (∼8% at 60 keV, 10 μs), MIRAX will be optimized for the detection and study of transient sources, such as accreting neutron stars (NS), black holes (BH), Active Galactic Nuclei (AGNs), and both short and long GRBs. This is especially important because MIRAX is expected to operate in an epoch when probably no other hard X-ray wide-field imager will be active. We have performed detailed simulations of MIRAX GRB observations using the GEANT4 package, including the background spectrum and images of GRB sources in order to provide accurate predictions of the sensitivity for the expected GRB rate to be observed. MIRAX will be capable of detecting ∼44 GRBs per year up to redshifts of ∼4.5. The MIRAX mission will be able to contribute significantly to GRB science by detecting a large number of GRBs per year with wide band spectral response. The observations will contribute mainly to the part of GRB spectra where a thermal emission is predicted by the Fireball model. We also discuss the possibility of detecting GRB afterglows in the X-ray band with MIRAX.

  10. Two-fluid model for transient analysis of slug flow in oil wells

    Energy Technology Data Exchange (ETDEWEB)

    Cazarez-Candia, O., E-mail: ocazarez@imp.mx [Instituto Mexicano del Petroleo, Eje central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico D.F. 07730 (Mexico); Instituto Tecnologico de Zacatepec, Depto. de Metal-Mecanica, Calzada Tecnologico, No. 27, Zacatepec, Morelos 62780 (Mexico); Benitez-Centeno, O.C. [Centro Nacional de Investigacion y Desarrollo Tecnologico, Depto. de Mecanica, Interior Internado Palmira s/n, Col. Palmira, Cuernavaca, Morelos 62490 (Mexico); Espinosa-Paredes, G. [Area de Ingenieria en Recursos Energeticos, Universidad Autonoma Metropolitana-Iztapalapa, Av San Rafael Atlixco No 186, Col. Vicentina 55-534, Mexico D.F. 09340 (Mexico)

    2011-06-15

    In this work it is presented a transient, one-dimensional, adiabatic model for slug flow simulation, which appears when liquid (mixture of oil and water) and gas flow simultaneously through pipes. The model is formed by space and time averaged conservation equations for mass, momentum and energy for each phase, the numerical solution is based on the finite difference technique in the implicit scheme. Velocity, pressure, volumetric fraction and temperature profiles for both phases were predicted for inclination angles from the horizontal to the vertical position (unified model) and ascendant flow. Predictions from the model were validated using field data and ten correlations commonly used in the oil industry. The effects of gas heating or cooling, due to compression and expansion processes, on the predictions and numerical stability, were studied. It was found that when these effects are taken into account, a good behavior of temperature predictions and numerical stability are obtained. The model presents deviations lower than 14% regarding field data and it presents better predictions than most of the correlations.

  11. Two-fluid model for transient analysis of slug flow in oil wells

    International Nuclear Information System (INIS)

    In this work it is presented a transient, one-dimensional, adiabatic model for slug flow simulation, which appears when liquid (mixture of oil and water) and gas flow simultaneously through pipes. The model is formed by space and time averaged conservation equations for mass, momentum and energy for each phase, the numerical solution is based on the finite difference technique in the implicit scheme. Velocity, pressure, volumetric fraction and temperature profiles for both phases were predicted for inclination angles from the horizontal to the vertical position (unified model) and ascendant flow. Predictions from the model were validated using field data and ten correlations commonly used in the oil industry. The effects of gas heating or cooling, due to compression and expansion processes, on the predictions and numerical stability, were studied. It was found that when these effects are taken into account, a good behavior of temperature predictions and numerical stability are obtained. The model presents deviations lower than 14% regarding field data and it presents better predictions than most of the correlations.

  12. Neuronal responses to water flow in the marine slug tritonia diomedea

    Directory of Open Access Journals (Sweden)

    Jeffrey Blackwell

    2005-07-01

    Full Text Available The marine slug Tritonia diomedea must rely on its ability to touch and smell in order to navigate because it is blind. The primary factor that influences its crawling direction is the direction of water flow (caused by tides in nature. The sensory cells that detect flow and determine flow direction have not been identified. The lateral branch of Cerebral Nerve 2 (latCeN2 has been identified as the nerve that carries sensory axons to the brain from the flow receptors inthe oral tentacles. Backfilling this nerve to the brain resulted in the labeling of a number of cells located throughout the brain. Most of the labeled cells are concentrated in the cerebral ganglion where the nerve enters the brain. The medial and lateral branches of CeN2 were backfilled for comparison of the pattern of cells from each nerve. A map of the cells innervated by latCeN2 reveals the location of the stained cells. Extracellular recording from latCeN2 revealed its involvement in the detection of water flow and orientation. The nerve becomes active in response to water flow stimulation. Intracellular recordings of the electrical activity of these cells in a live animal will be the next step to determine if these cells are the flow receptors.

  13. Neuronal Responses to Water Flow in the Marine Slug Tritonia diomedea

    Directory of Open Access Journals (Sweden)

    James A. Murray

    2005-01-01

    Full Text Available The marine slug Tritonia diomedea mustrely on its ability to touch and smell in order to navigate because it is blind. The primaryfactor that influences its crawling direction is the direction of water flow (caused bytides in nature. The sensory cells that detect flow and determine flow directionhave not been identified. The lateral branch of Cerebral Nerve 2 (latCeN2 has beenidentified as the nerve that carries sensory axons to the brain from the flow receptors inthe oral tentacles. Backfilling this nerve to the brain resulted in the labeling of a numberof cells located throughout the brain. Most of the labeled cells are concentrated in the cerebral ganglion where the nerve enters thebrain. The medial and lateral branches of CeN2 were backfilled for comparison of thepattern of cells from each nerve. A map of the cells innervated by latCeN2 reveals thelocation of the stained cells. Extracellular recording from latCeN2 revealed itsinvolvement in the detection of water flow and orientation. The nerve becomes activein response to water flow stimulation. Intracellular recordings of the electricalactivity of these cells in a live animal will be the next step to determine if these cells arethe flow receptors.

  14. Detection of spectral evolution in the bursts emitted during the 2008-2009 active episode of SGR J1550 - 5418

    CERN Document Server

    von Kienlin, Andreas; Kouveliotou, Chryssa; Granot, Jonathan; Baring, Matthew G; Göğüş, Ersin; Huppenkothen, Daniela; Kaneko, Yuki; Lin, Lin; Watts, Anna L; Bhat, P Narayana; Guiriec, Sylvain; van der Horst, Alexander J; Bissaldi, Elisabetta; Greiner, Jochen; Meegan, Charles A; Paciesas, William S; Preece, Robert D; Rau, Arne

    2012-01-01

    In early October 2008, the Soft Gamma Repeater SGRJ1550 - 5418 (1E 1547.0 - 5408, AXJ155052 - 5418, PSR J1550 - 5418) became active, emitting a series of bursts which triggered the Fermi Gamma-ray Burst Monitor (GBM) after which a second especially intense activity period commenced in 2009 January and a third, less active period was detected in 2009 March-April. Here we analyze the GBM data all the bursts from the first and last active episodes. We performed temporal and spectral analysis for all events and found that their temporal characteristics are very similar to the ones of other SGR bursts, as well the ones reported for the bursts of the main episode (average burst durations \\sim 170 ms). In addition, we used our sample of bursts to quantify the systematic uncertainties of the GBM location algorithm for soft gamma-ray transients to < 8 deg. Our spectral analysis indicates significant spectral evolution between the first and last set of events. Although the 2008 October events are best fit with a sin...

  15. A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to cAMP and differential sensitivity to suppression of chemotaxis by ammonia

    Indian Academy of Sciences (India)

    Ira N Feit; Jeffrey Pawlikowski; Caroline Zawilski

    2007-03-01

    The three basic cell types in the migrating slug of Dictyostelium discoideum show differential chemotactic response to cyclic AMP (cAMP) and differential sensitivity to suppression of the chemotaxis by ammonia. The values of these parameters indicate a progressive maturation of chemotactic properties during the transdifferentiation of slug cell types. We present a model that explains the localization of the three cell types within the slug based on these chemotactic differences and on the maturation of their chemotactic properties.

  16. A novel data channel fault detection mechanism in optical burst switching networks

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Fault detection in optical burst switching (OBS) networks will be a challenging task in the future. A novel mechanism based on probe burst (PB) and a new key concept is proposed to detect faults of OBS networks by sampling the health of data channels, which solve the difficulty of optical monitoring schemes while keeps the transparency of data network to Internet protocol (IP) packets. It takes full advantage of the characteristics of OBS, including architecture and signalling scheme, and introduces the excellent performances of single-hop-test used in electrical communication networks into OBS environment while avoids the shortcoming that any optical burst must undergo an optical-electric-optical (OEO) conversion.Well designed PB can provide exact criterion for judging whether protection/restoration should be excuted according to hard or soft fault identification.

  17. Radiosensitivity of AsPC-1 cell to γ-rays enhanced by up-regulation of PUMA induced by targeted Slug gene

    International Nuclear Information System (INIS)

    Objective: To explore the influence of PUMA on radiosensitivity of pancreatic cancer AsPC-1 cells after Slug gene inhibition by transfected short interferencing RNA (siRNA). Methods: The AsPC-1 cells were infected with MOI 10, 50, 100 for 72 h, respectively. The expression of Slug and PUMA was analyzed by Western blotting and immunohistochemistry methods. The transfected and control cells were exposed to 4 Gy γ-rays. The cells inhibition rate was examined by MTT, Hoechst 33342 and IP double staining. DNA ladder and Giemsa staning was used to observe apoptosis. Results: The relative value of Slug expression was 0.831±0.14, 0.546±0.12 and 0.178±0.08 after AsPC-1 was infected with Slug-siRNA (MOI 10, 50, 100) for 72 h, significantly lower than that of control group (F=4.992, P<0.05). The relative value of PUMA was 0.325±0.07, 0.593±0.11 and 0.978±0.12, after AsPC-1 was infected with Slug-siRNA (MOI 10, 50, 100) for 72 h, significantly higher than that of control group (F=4.324, P<0.05). The cell proliferation rate was (78.76±9.36)% in transfection combined with radiosensitivity group, significantly higher than that of transfection group [(43.68±6.71)%] and radiosensitivity group alone [(19.25±3.72)%] (F=5.056, P<0.05). The apoptosis of transfection combined with radiosensitivity group was significantly higher than that of others. Conclusions: Slug gene targeting siRNA could inhibit the expression of Slug, and consequently increase the activation of PUMA expression, and so enhance the radiosensitivity to γ-rays. (authors)

  18. Ling Zhi-8 reduces lung cancer mobility and metastasis through disruption of focal adhesion and induction of MDM2-mediated Slug degradation.

    Science.gov (United States)

    Lin, Tung-Yi; Hsu, Hsien-Yeh

    2016-06-01

    We recently reported that recombinant Ling Zhi-8 (rLZ-8), a medicinal mushroom Ganoderma lucidum recombinant protein, effectively prevents lung cancer cells proliferation in vivo mice model. In our current study, we demonstrated that rLZ-8 suppressed tumor metastasis and increased the survival rate in Lewis lung carcinoma cell-bearing mice. The epithelial to mesenchymal transition (EMT) process is regarded as the critical event in tumor metastasis. Herein, we showed that rLZ-8 effectively induced changes in EMT by interfering with cell adhesion and focal adhesion kinase (FAK) functions in lung cancer cells. Slug, a transcription factor, represses E-cadherin transcription and is regarded as a critical event in EMT and tumor metastasis. Functional studies revealed that downregulation of Slug as a result of rLZ-8-induced FAK inactivation enhanced E-cadherin expression and repressed cancer cell mobility. Moreover, we found that rLZ-8 enhanced the ubiquitination proteasome pathway (UPP)-mediated degradation of Slug in CL1-5 cells. Mechanistically, we demonstrated that rLZ-8 promoted the interaction between MDM2 and Slug, resulting in Slug degradation; however, MDM2-shRNA abolished rLZ-8-enhanced Slug degradation. This study is the first to determine anti-metastatic activity of rLZ-8 and its potential mechanism, with how the regulation of EMT and cell mobility is via the negative modulation of FAK, and thereby leading to the ubiquitination and degradation of Slug. Our findings suggest that the targets of FAK play a key role in metastasis. Moreover, rLZ-8 may be useful as a chemotherapeutic agent for treating lung cancer. PMID:26992741

  19. TEMPORAL DECONVOLUTION STUDY OF LONG AND SHORT GAMMA-RAY BURST LIGHT CURVES

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, P. N.; Briggs, Michael S.; Connaughton, Valerie; Paciesas, William; Burgess, Michael; Chaplin, Vandiver; Goldstein, Adam; Guiriec, Sylvain [Center for Space Plasma and Aeronomic Research (CSPAR), University of Alabama in Huntsville, NSSTC, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Kouveliotou, Chryssa; Fishman, Gerald [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Van der Horst, Alexander J.; Meegan, Charles A. [Center for Space Plasma and Aeronomic Research (CSPAR), Universities Space Research Association, NSSTC, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Bissaldi, Elisabetta [Institute of Astro and Particle Physics, University of Innsbruck, Technikerstr. 25, 6020 Innsbruck (Austria); Diehl, Roland; Foley, Suzanne; Greiner, Jochen; Gruber, David [Max-Planck-Institut fuer Extraterrestrische Physik, Giessenbachstrasse 1, 85748 Garching (Germany); Fitzpatrick, Gerard [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Gibby, Melissa; Giles, Misty M. [Jacobs Technology, Inc., Huntsville, AL 35806 (United States); and others

    2012-01-10

    The light curves of gamma-ray bursts (GRBs) are believed to result from internal shocks reflecting the activity of the GRB central engine. Their temporal deconvolution can reveal potential differences in the properties of the central engines in the two populations of GRBs which are believed to originate from the deaths of massive stars (long) and from mergers of compact objects (short). We present here the results of the temporal analysis of 42 GRBs detected with the Gamma-ray Burst Monitor onboard the Fermi Gamma-ray Space Telescope. We deconvolved the profiles into pulses, which we fit with lognormal functions. The distributions of the pulse shape parameters and intervals between neighboring pulses are distinct for both burst types and also fit with lognormal functions. We have studied the evolution of these parameters in different energy bands and found that they differ between long and short bursts. We discuss the implications of the differences in the temporal properties of long and short bursts within the framework of the internal shock model for GRB prompt emission.

  20. The Interplanetary Network Supplement to the Fermi GBM Catalog of Cosmic Gamma-Ray Bursts

    CERN Document Server

    Hurley, K; Aptekar, R L; Golenetskii, S V; Frederiks, D D; Mazets, E P; Svinkin, D S; Briggs, M S; Connaughton, V; Meegan, C; Goldsten, J; Boynton, W; Fellows, C; Harshman, K; Mitrofanov, I G; Golovin, D V; Kozyrev, A S; Litvak, M L; Sanin, A B; Rau, A; von Kienlin, A; Zhang, X; Yamaoka, K; Fukazawa, Y; Hanabata, Y; Ohno, M; Takahashi, T; Tashiro, M; Terada, Y; Murakami, T; Makishima, K; Barthelmy, S; Cline, T; Gehrels, N; Cummings, J; Krimm, H A; Smith, D M; Del Monte, E; Feroci, M; Marisaldi, M

    2013-01-01

    We present Interplanetary Network (IPN) data for the gamma-ray bursts in the first Fermi Gamma-Ray Burst Monitor (GBM) catalog. Of the 491 bursts in that catalog, covering 2008 July 12 to 2010 July 11, 393 were observed by at least one other instrument in the 9-spacecraft IPN. Of the 393, the localizations of 146 could be improved by arrival time analysis (or "triangulation"). For any given burst observed by the GBM and one other distant spacecraft, triangulation gives an annulus of possible arrival directions whose half-width varies between about 0.4 arcminutes and 32 degrees, depending on the intensity, time history, and arrival direction of the burst, as well as the distance between the spacecraft. We find that the IPN localizations intersect the 1 sigma GBM error circles in only 52% of the cases, if no systematic uncertainty is assumed for the latter. If a 6 degree systematic uncertainty is assumed and added in quadrature, the two localization samples agree about 87% of the time, as would be expected. If ...

  1. Temporal Deconvolution study of Long and Short Gamma-Ray Burst Light curves

    CERN Document Server

    Bhat, P N; Connaughton, Valerie; Kouveliotou, Chryssa; van der Horst, Alexander J; Paciesas, William; Meegan, Charles A; Bissaldi, Elisabetta; Burgess, Michael; Chaplin, Vandiver; Diehl, Roland; Fishman, Gerald; Fitzpatrick, Gerard; Foley, Suzanne; Gibby, Melissa; Giles, Misty M; Goldstein, Adam; Greiner, Jochen; Gruber, David; Guiriec, Sylvain; von Kienlin, Andreas; Kippen, Marc; McBreen, Sheila; Preece, Robert; Rau, Arne; Tierney, Dave; Wilson-Hodge, Colleen

    2011-01-01

    The light curves of Gamma-Ray Bursts (GRBs) are believed to result from internal shocks reflecting the activity of the GRB central engine. Their temporal deconvolution can reveal potential differences in the properties of the central engines in the two populations of GRBs which are believed to originate from the deaths of massive stars (long) and from mergers of compact objects (short). We present here the results of the temporal analysis of 42 GRBs detected with the Gamma-ray Burst Monitor onboard the Fermi Gamma-ray Space Telescope. We deconvolved the profiles into pulses, which we fit with lognormal functions. The distributions of the pulse shape parameters and intervals between neighboring pulses are distinct for both burst types and also fit with lognormal functions. We have studied the evolution of these parameters in different energy bands and found that they differ between long and short bursts. We discuss the implications of the differences in the temporal properties of long and short bursts within t...

  2. Efficient inhibition of bursts by bursts in the auditory system of crickets.

    Science.gov (United States)

    Marsat, G; Pollack, G S

    2007-06-01

    In crickets, auditory information about ultrasound is carried bilaterally to the brain by the AN2 neurons. The ON1 neuron provides contralateral inhibitory input to AN2, thereby enhancing bilateral contrast between the left and right AN2s, an important cue for sound localization. We examine how the structures of the spike trains of these neurons affect this inhibitory interaction. As previously shown for AN2, ON1 responds to salient peaks in stimulus amplitude with bursts of spikes. Spike bursts, but not isolated spikes, reliably signal the occurrence of specific features of the stimulus. ON1 and AN2 burst at similar times relative to the amplitude envelope of the stimulus, and bursts are more tightly time-locked to stimulus feature than the isolated spikes. As a consequence, spikes that, in the absence of contralateral inhibition, would occur within AN2 bursts are more likely to be preceded by spikes in ON1 (mainly also in bursts) than are isolated AN2 spikes. This leads to a large decrease in the burst rate of the inhibited AN2. We conclude that the match in coding properties of ON1 and AN2 allows contralateral inhibition to be most efficient for those portions of the response that carry the behaviourally relevant information, i.e. for bursts.

  3. QKD-Based Secured Burst Integrity Design for Optical Burst Switched Networks

    Science.gov (United States)

    Balamurugan, A. M.; Sivasubramanian, A.; Parvathavarthini, B.

    2016-03-01

    The field of optical transmission has undergone numerous advancements and is still being researched mainly due to the fact that optical data transmission can be done at enormous speeds. It is quite evident that people prefer optical communication when it comes to large amount of data involving its transmission. The concept of switching in networks has matured enormously with several researches, architecture to implement and methods starting with Optical circuit switching to Optical Burst Switching. Optical burst switching is regarded as viable solution for switching bursts over networks but has several security vulnerabilities. However, this work exploited the security issues associated with Optical Burst Switching with respect to integrity of burst. This proposed Quantum Key based Secure Hash Algorithm (QKBSHA-512) with enhanced compression function design provides better avalanche effect over the conventional integrity algorithms.

  4. An Intelligent Segmented Burst Assembly Mechanism in Optical Burst Switching Networks

    Institute of Scientific and Technical Information of China (English)

    XIE Yi-Yuan; ZHANG Jian-Guo

    2008-01-01

    We focus on the burst assembly mechanism and propose a new intelligent method in which the burst is assembled from several internet protocol (IP) packets in which the number of IP packets is changed according to the traffic load and the burst is segmented into several parts, called the ISOBS mechanism. The average burst assembly time of the ISOBS mechanism decreases as compared with the fixed-assembly-time and fixed-assembly-time-and-length mechanisms. The loss ratio decreases 50% as compared with the general optical burst switching (OBS) mechanism. The last segment can carry high quality of service (QOS) information. We can achieve that the loss ratio of the last segment is almost zero when the traffic load is less than 0.05. When the traffic load is 0.9, the loss ratio of the last segment is 0.0041. The ISOBS can support to transmit different QOS data.

  5. An Intelligent Segmented Burst Assembly Mechanism in Optical Burst Switching Networks

    International Nuclear Information System (INIS)

    We focus on the burst assembly mechanism and propose a new intelligent method in which the burst is assembled from several internet protocol (IP) packets in which the number of IP packets is changed according to the traffic load and the burst is segmented into several parts, called the ISOBS mechanism. The average burst assembly time of the ISOBS mechanism decreases as compared with the fixed-assembly-time and fixed-assembly-time-and-length mechanisms. The loss ratio decreases 50% as compared with the general optical burst switching (OBS) mechanism. The last segment can carry high quality of service (QOS) information. We can achieve that the loss ratio of the last segment is almost zero when the traffic load is less than 0.05. When the traffic load is 0.9, the loss ratio of the last segment is 0.0041. The ISOBS can support to transmit different QOS data. (fundamental areas of phenomenology (including applications))

  6. Diagnostics From Three Rising Submillimeter Bursts

    CERN Document Server

    Zhou, Ai-Hua; Wang, Xin-Dong

    2015-01-01

    In the paper we investigate three novel rising submillimeter (THz) bursts occurred sequentially in a super-Active Region NOAA 10486. The average rising rate of the flux density above 200 GHz is only 20 sfu/GHz (corresponding spectral index $\\alpha$ of 1.6) for the THz spectral components of 2003 October 28 and November 4 bursts, while it can attain values of 235 sfu/GHz ($\\alpha$=4.8) for 2003 November 2 burst. The steeply rising THz spectrum can be produced by a population of high relativistic electrons with a low-energy cutoff of 1 MeV , while it only requires a low-energy cutoff of 30 keV for the two slowly rising THz bursts, via gyrosynchrotron (GS) radiation based on our numerical simulations of burst spectra in the magnetic dipole field case. The electron density variation is much larger in the THz source than that in microwave (MW) one. It is interesting that the THz source radius decreased by 20--50$\\%$ during the decay phase for the three events, but the MW one increased by 28$\\%$ for the 2003 Novemb...

  7. Sources of type III solar microwave bursts

    Science.gov (United States)

    Zhdanov, Dmitriy; Lesovoi, Sergey; Tokhchukova, Susanna

    2016-06-01

    Microwave fine structures allow us to study plasma evolution in an energy release region. The Siberian Solar Radio Telescope (SSRT) is a unique instrument designed to examine fine structures at 5.7 GHz. A complex analysis of data from RATAN-600, 4-8 GHz spectropolarimeter, and SSRT, simultaneously with extreme UV data, made it possible to localize sources of III type microwave drift bursts in August 10, 2011 event within the entire frequency band of burst occurrences, as well as to determine the most probable region of primary energy release. To localize sources of III type bursts from RATAN-600 data, an original method for data processing has been worked out. At 5.7 GHz, the source of bursts was determined along two coordinates whereas at 4.5, 4.7, 4.9, 5.1, 5.3, 5.5 and 6.0 GHz, their locations were identified along one coordinate. The size of the burst source at 5.1 GHz was found to be maximum as compared to source sizes at other frequencies.

  8. Bursting synchronization in clustered neuronal networks

    Institute of Scientific and Technical Information of China (English)

    Yu Hai-Tao; Wang Jiang; Deng Bin; Wei Xi-Le

    2013-01-01

    Neuronal networks in the brain exhibit the modular (clustered) property,i.e.,they are composed of certain subnetworks with differential internal and external connectivity.We investigate bursting synchronization in a clustered neuronal network.A transition to mutual-phase synchronization takes place on the bursting time scale of coupled neurons,while on the spiking time scale,they behave asynchronously.This synchronization transition can be induced by the variations of inter-and intracoupling strengths,as well as the probability of random links between different subnetworks.Considering that some pathological conditions are related with the synchronization of bursting neurons in the brain,we analyze the control of bursting synchronization by using a time-periodic external signal in the clustered neuronal network.Simulation results show a frequency locking tongue in the driving parameter plane,where bursting synchronization is maintained,even in the presence of external driving.Hence,effective synchronization suppression can be realized with the driving parameters outside the frequency locking region.

  9. Focal mechanism caused by fracture or burst of a coal pillar

    Institute of Scientific and Technical Information of China (English)

    CAO An-ye; DOU Lin-ming; CHEN Guo-xiang; GONG Si-yuan; WANG Yu-gang; LI Zhi-hua

    2008-01-01

    As a regional, real-time and dynamic method, microseismic monitoring technology is quite an appropriate technology for forecasting geological hazards, such as rock bursts, mine tremors, coal and gas outbursts and can even be used to prevent or at least reduce these disasters. The study of the focal mechanisms of different seismic sources is the prerequisite and basis for forecasting rock burst by microseismic monitoring technology. Based on the analysis on the mechanism and fracture course of coal pillars where rock bursts occur mostly, the equivalent point source model of the seismicity caused by a coal pillar was created. Given the model, the seismic displacement equation of a coal pillar was analyzed and the seismic mechanism was pointed out by seismic wave theory. The course of the fracture of the coal pillar was simulated closely in the laboratory and the equivalent microseismic signals of the fractures of the coal pillar were acquired using a TDS-6 experimental system. The results show that, by the pressure and friction of a medium near the seismic source, both a compression wave and a shear wave will be emitted and shear fracture will be induced at the moment of breakage. The results can be used to provide an academic basis to forecast and prevent rock bursts or tremors in a coal pillar.

  10. Slug impact loading on the vessel head during a postulated in-vessel steam explosion in pressurized water reactors -- Assessments and discussion of the investigation strategy

    International Nuclear Information System (INIS)

    The most severe consequence of a pressurized water reactor in-vessel steam explosion is a molten fuel slug impact against the head of the reactor pressure vessel that could cause a failure of this head and lead to missiles endangering the reactor containment. An investigation is described that attempts to determine the maximum slug impact that a vessel head is capable of withstanding without failing and, consequently, without impairing the containment safety-related function. Preliminary theoretical assessments are presented that suggest that the head might be able to withstand rather strong impacts and that the shape of the fuel slug will have only a moderate influence on the results, provided the upper internal structures are taken into account. A low sensitivity against the slug shape is an essential prerequisite for a reliable safety proof. However, investigations primarily based on computational models are not sufficient; therefore, an investigation concept is proposed that relies on model experiments in which the geometry is scaled down by factors of 10 and 20, respectively. Theoretical and experimental investigations for liquid-structure impact problems in different scales are discussed to assess the degree of similarity that can be obtained. Finally, model experiments are described in some detail simulating the molten fuel slug impact on the vessel head

  11. 3-dimensional Simulation of an Air-lift Pump from Bubbly to Slug Flow

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Hongrae; Jo, Daeseong [Kyungpook National Univ, Daegu (Korea, Republic of)

    2015-10-15

    The air-lift pump has been used in various applications with its merit that it can pump up without any moving parts. E.g. coffee percolator, petroleum industry, suction dredge, OTEC i.e. ocean thermal energy conversion and so on. By the merit, it has high durability for high temperature water or vapor, and fluid-solid mixture like waste water, muddy water and crude, which cause problems when it's pumped up with general pumps. In this regard, the air-lift pump has been one of the most desirable technology. A typical air-lift pump configuration is illustrated in Figure 01. The principle of this pump is very simple. When air is injected from the injector at bottom of a submerged tube, i.e., air bubbles are suspended in the liquid, the average density of the mixture in the tube is less than that of the surrounding fluid in the reservoir. Then hydrostatic pressure over the length of the tube is decreased. This buoyancy force causes a pumping action. The comparison of the simulated results, experimental result, and theoretical result is been able by data shown as Figure 04. They have similar trends but they also have a little differences because there are some limits of simulating the flow regimes. At the different flow condition, different coefficients for friction factor or pressure drop should be used, but this simulation uses a laminar condition and the theoretical equations are valid only for slug regime where the air flow rate is lower than the other regimes. From these causes, the differences has arisen, and difference comes bigger as the air flow rate increases, i.e., becoming annular flow regime or churn flow regime.

  12. THE FIRST FERMI-LAT GAMMA-RAY BURST CATALOG

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, M. [Deutsches Elektronen Synchrotron DESY, D-15738 Zeuthen (Germany); Ajello, M. [Space Sciences Laboratory, 7 Gauss Way, University of California, Berkeley, CA 94720-7450 (United States); Asano, K. [Interactive Research Center of Science, Tokyo Institute of Technology, Meguro City, Tokyo 152-8551 (Japan); Axelsson, M. [Department of Astronomy, Stockholm University, SE-106 91 Stockholm (Sweden); Baldini, L. [Università di Pisa and Istituto Nazionale di Fisica Nucleare, Sezione di Pisa I-56127 Pisa (Italy); Ballet, J. [Laboratoire AIM, CEA-IRFU/CNRS/Université Paris Diderot, Service d' Astrophysique, CEA Saclay, 91191 Gif sur Yvette (France); Barbiellini, G. [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, I-34127 Trieste (Italy); Bastieri, D. [Istituto Nazionale di Fisica Nucleare, Sezione di Padova, I-35131 Padova (Italy); Bechtol, K.; Bloom, E. D. [W. W. Hansen Experimental Physics Laboratory, Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, Stanford, CA 94305 (United States); Bellazzini, R.; Bregeon, J. [Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, I-56127 Pisa (Italy); Bhat, P. N. [Center for Space Plasma and Aeronomic Research (CSPAR), University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Bissaldi, E. [Institut für Astro- und Teilchenphysik and Institut für Theoretische Physik, Leopold-Franzens-Universität Innsbruck, A-6020 Innsbruck (Austria); Bonamente, E. [Istituto Nazionale di Fisica Nucleare, Sezione di Perugia, I-06123 Perugia (Italy); Bonnell, J.; Brandt, T. J. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Bouvier, A., E-mail: nicola.omodei@stanford.edu, E-mail: giacomov@slac.stanford.edu [Santa Cruz Institute for Particle Physics, Department of Physics and Department of Astronomy and Astrophysics, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); and others

    2013-11-01

    In three years of observations since the beginning of nominal science operations in 2008 August, the Large Area Telescope (LAT) on board the Fermi Gamma-Ray Space Telescope has observed high-energy (∼> 20 MeV) γ-ray emission from 35 gamma-ray bursts (GRBs). Among these, 28 GRBs have been detected above 100 MeV and 7 GRBs above ∼20 MeV. The first Fermi-LAT catalog of GRBs is a compilation of these detections and provides a systematic study of high-energy emission from GRBs for the first time. To generate the catalog, we examined 733 GRBs detected by the Gamma-Ray Burst Monitor (GBM) on Fermi and processed each of them using the same analysis sequence. Details of the methodology followed by the LAT collaboration for the GRB analysis are provided. We summarize the temporal and spectral properties of the LAT-detected GRBs. We also discuss characteristics of LAT-detected emission such as its delayed onset and longer duration compared with emission detected by the GBM, its power-law temporal decay at late times, and the fact that it is dominated by a power-law spectral component that appears in addition to the usual Band model.

  13. THE FIRST FERMI-LAT GAMMA-RAY BURST CATALOG

    International Nuclear Information System (INIS)

    In three years of observations since the beginning of nominal science operations in 2008 August, the Large Area Telescope (LAT) on board the Fermi Gamma-Ray Space Telescope has observed high-energy (∼> 20 MeV) γ-ray emission from 35 gamma-ray bursts (GRBs). Among these, 28 GRBs have been detected above 100 MeV and 7 GRBs above ∼20 MeV. The first Fermi-LAT catalog of GRBs is a compilation of these detections and provides a systematic study of high-energy emission from GRBs for the first time. To generate the catalog, we examined 733 GRBs detected by the Gamma-Ray Burst Monitor (GBM) on Fermi and processed each of them using the same analysis sequence. Details of the methodology followed by the LAT collaboration for the GRB analysis are provided. We summarize the temporal and spectral properties of the LAT-detected GRBs. We also discuss characteristics of LAT-detected emission such as its delayed onset and longer duration compared with emission detected by the GBM, its power-law temporal decay at late times, and the fact that it is dominated by a power-law spectral component that appears in addition to the usual Band model

  14. The First Fermi-LAT Gamma-Ray Burst Catalog

    Science.gov (United States)

    Ackermann, M.; Ajello, M.; Asano, K.; Axelsson, M.; Baldini, L.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Bechtol, K.; Bellazzini, R.; Bhat, P. N.; Bissaldi, E.; Bloom, E. D.; Bonamente, E.; Bonnell, J.; Bouvier, A.; Brandt, T. J.; Bregeon, J.; Brigida, M.; Bruel, P.; Buehler, R.; Burgess, J. Michael; Buson, S.; Byrne, D.; Caliandro, G. A.; Cameron, R. A.; Caraveo, P. A.; Cecchi, C.; Charles, E.; Chaves, R. C. G.; Chekhtman, A.; Chiang, J.; Chiaro, G.; Ciprini, S.; Claus, R.; Cohen-Tanugi, J.; Connaughton, V.; Conrad, J.; Cutini, S.; D'Ammando, F.; de Angelis, A.; de Palma, F.; Dermer, C. D.; Desiante, R.; Digel, S. W.; Dingus, B. L.; Di Venere, L.; Drell, P. S.; Drlica-Wagner, A.; Dubois, R.; Favuzzi, C.; Ferrara, E. C.; Fitzpatrick, G.; Foley, S.; Franckowiak, A.; Fukazawa, Y.; Fusco, P.; Gargano, F.; Gasparrini, D.; Gehrels, N.; Germani, S.; Giglietto, N.; Giommi, P.; Giordano, F.; Giroletti, M.; Glanzman, T.; Godfrey, G.; Goldstein, A.; Granot, J.; Grenier, I. A.; Grove, J. E.; Gruber, D.; Guiriec, S.; Hadasch, D.; Hanabata, Y.; Hayashida, M.; Horan, D.; Hou, X.; Hughes, R. E.; Inoue, Y.; Jackson, M. S.; Jogler, T.; Jóhannesson, G.; Johnson, A. S.; Johnson, W. N.; Kamae, T.; Kataoka, J.; Kawano, T.; Kippen, R. M.; Knödlseder, J.; Kocevski, D.; Kouveliotou, C.; Kuss, M.; Lande, J.; Larsson, S.; Latronico, L.; Lee, S.-H.; Longo, F.; Loparco, F.; Lovellette, M. N.; Lubrano, P.; Massaro, F.; Mayer, M.; Mazziotta, M. N.; McBreen, S.; McEnery, J. E.; McGlynn, S.; Michelson, P. F.; Mizuno, T.; Moiseev, A. A.; Monte, C.; Monzani, M. E.; Moretti, E.; Morselli, A.; Murgia, S.; Nemmen, R.; Nuss, E.; Nymark, T.; Ohno, M.; Ohsugi, T.; Omodei, N.; Orienti, M.; Orlando, E.; Paciesas, W. S.; Paneque, D.; Panetta, J. H.; Pelassa, V.; Perkins, J. S.; Pesce-Rollins, M.; Piron, F.; Pivato, G.; Porter, T. A.; Preece, R.; Racusin, J. L.; Rainò, S.; Rando, R.; Rau, A.; Razzano, M.; Razzaque, S.; Reimer, A.; Reimer, O.; Reposeur, T.; Ritz, S.; Romoli, C.; Roth, M.; Ryde, F.; Saz Parkinson, P. M.; Schalk, T. L.; Sgrò, C.; Siskind, E. J.; Sonbas, E.; Spandre, G.; Spinelli, P.; Suson, D. J.; Tajima, H.; Takahashi, H.; Takeuchi, Y.; Tanaka, Y.; Thayer, J. G.; Thayer, J. B.; Thompson, D. J.; Tibaldo, L.; Tierney, D.; Tinivella, M.; Torres, D. F.; Tosti, G.; Troja, E.; Tronconi, V.; Usher, T. L.; Vandenbroucke, J.; van der Horst, A. J.; Vasileiou, V.; Vianello, G.; Vitale, V.; von Kienlin, A.; Winer, B. L.; Wood, K. S.; Wood, M.; Xiong, S.; Yang, Z.

    2013-11-01

    In three years of observations since the beginning of nominal science operations in 2008 August, the Large Area Telescope (LAT) on board the Fermi Gamma-Ray Space Telescope has observed high-energy (gsim 20 MeV) γ-ray emission from 35 gamma-ray bursts (GRBs). Among these, 28 GRBs have been detected above 100 MeV and 7 GRBs above ~20 MeV. The first Fermi-LAT catalog of GRBs is a compilation of these detections and provides a systematic study of high-energy emission from GRBs for the first time. To generate the catalog, we examined 733 GRBs detected by the Gamma-Ray Burst Monitor (GBM) on Fermi and processed each of them using the same analysis sequence. Details of the methodology followed by the LAT collaboration for the GRB analysis are provided. We summarize the temporal and spectral properties of the LAT-detected GRBs. We also discuss characteristics of LAT-detected emission such as its delayed onset and longer duration compared with emission detected by the GBM, its power-law temporal decay at late times, and the fact that it is dominated by a power-law spectral component that appears in addition to the usual Band model.

  15. Bursting activity spreading through asymmetric interactions

    CERN Document Server

    Onaga, Tomokatsu

    2014-01-01

    People communicate with those who have the same background or share a common interest by using a social networking service (SNS). News or messages propagate through inhomogeneous connections in an SNS by sharing or facilitating additional comments. Such human activity is known to lead to endogenous bursting in the rate of message occurrences. We analyze a multi-dimensional self-exciting process to reveal dependence of the bursting activity on the topology of connections and the distribution of interaction strength on the connections. We determine the critical conditions for the cases where interaction strength is regulated at either the point of input or output for each person. In the input regulation condition, the network may exhibit bursting with infinitesimal interaction strength, if the dispersion of the degrees diverges as in the scale-free networks. In contrast, in the output regulation condition, the critical value of interaction strength, represented by the average number of events added by a single ...

  16. Variable protostellar accretion with episodic bursts

    CERN Document Server

    Vorobyov, Eduard I

    2015-01-01

    We present the latest development of the disk gravitational instability and fragmentation model, originally introduced by us to explain episodic accretion bursts in the early stages of star formation. Using our numerical hydrodynamics model with improved disk thermal balance and star-disk interaction, we computed the evolution of protostellar disks formed from the gravitational collapse of prestellar cores. In agreement with our previous studies, we find that cores of higher initial mass and angular momentum produce disks that are more favorable to gravitational instability and fragmentation, while a higher background irradiation and magnetic fields moderate the disk tendency to fragment. The protostellar accretion in our models is time-variable, thanks to the nonlinear interaction between different spiral modes in the gravitationally unstable disk, and can undergo episodic bursts when fragments migrate onto the star owing to the gravitational interaction with other fragments or spiral arms. Most bursts occur...

  17. Gamma-ray bursts and cosmology.

    Science.gov (United States)

    Lamb, D Q

    2007-05-15

    I review the current status of the use of gamma-ray bursts (GRBs) as probes of the early Universe and cosmology. I describe the promise of long GRBs as probes of the high redshift (z>4) and very high redshift (z>5) Universe, and several key scientific results that have come from observations made possible by accurate, rapid localizations of these bursts by Swift. I then estimate the fraction of long GRBs that lie at very high redshifts and discuss ways in which it may be possible to rapidly identify-and therefore study-a larger number of these bursts. Finally, I discuss the ways in which both long and short GRBs can be made 'standard candles' and used to constrain the properties of dark energy. PMID:17301023

  18. Study on fault induced rock bursts

    Institute of Scientific and Technical Information of China (English)

    LI Zhi-hua; DOU Lin-ming; LU Cai-ping; MU Zong-long; CAO An-ye

    2008-01-01

    In order to study the rules of rock bursts caused by faults by means of mechanical analysis of a roof rock-mass balanced structure and numerical simulation about fault slip destabilization, the effect of coal mining operation on fault plane stresses and slip displacement were studied. The results indicate that the slip displacement sharply increases due to the decrease of normal stress and the increase of shear stress at the fault plane when the working face advances from the footwall to the fault itself, which may induce a fault rock burst. However, this slip displacement will be very small due to the increase of normal stress and the decrease of shear stress when the working face advances from the hanging wall to the fault itself, which results in a very small risk of a fault rock burst.

  19. On the bursting of gene products

    CERN Document Server

    Yvinec, Romain

    2011-01-01

    In this article we demonstrate that the so-called bursting production of molecular species during gene expression may be an artifact caused by low time resolution in experimental data collection and not an actual burst in production. We reach this conclusion through an analysis of a two-stage and binary model for gene expression, and demonstrate that in the limit when mRNA degradation is much faster than protein degradation they are equivalent. The negative binomial distribution is shown to be a limiting case of the binary model for fast "on to off" state transitions and high values of the ratio between protein synthesis and degradation rates. The gene products population increases by unity but multiple times in a time interval orders of magnitude smaller than protein half-life or the precision of the experimental apparatus employed in its detection. This rare-and-fast one-by-one protein synthesis has been interpreted as bursting.

  20. Gamma Ray Bursts Observations and Theoretical Conjectures

    CERN Document Server

    Alagoz, E; Carrillo, C; Golup, G T; Grimes, M; Herrera, Mora C; Gallo, Palomino J L; López, Vega A; Wicht, J

    2008-01-01

    Gamma Ray Bursts (GRBs) are short bursts of very high energy photons which were discovered in the late 1960s. Ever since their discovery, scientists have wondered about their origin. Nowadays it is known that they originate outside the Milky Way because of their high red shift rst measured in the afterglows thanks to the Beppo-SAX satellite and ground-based observations. However, theoreticians still do not agree about the mechanism that generates the bursts, and different competing models are animatedly debated. Current GRB experiments include the Swift satellite and the Pierre Auger Observatory that could detect GRBs with an increase of the background. A forthcoming dedicated experiment is GLAST, a satellite observatory for detecting gamma rays with energies up to 300 GeV, whose launch is scheduled for early 2008.

  1. A mechanism for fast radio bursts

    CERN Document Server

    Romero, Gustavo E; Vieyro, Florencia L

    2015-01-01

    Fast radio bursts are mysterious transient sources likely located at cosmological distances. The derived brightness temperatures exceed by many orders of magnitude the self-absorption limit of incoherent synchrotron radiation, implying the operation of a coherent emission process. We propose a radiation mechanism for fast radio bursts where the emission arises from collisionless Bremsstrahlung in strong plasma turbulence excited by relativistic electron beams. We discuss possible astrophysical scenarios in which this process might operate. The emitting region is a turbulent plasma hit by a relativistic jet, where Langmuir plasma waves produce a concentration of intense electrostatic soliton-like regions (cavitons). The resulting radiation is coherent and, under some physical conditions, can be polarised and have a power-law distribution in energy. We obtain radio luminosities in agreement with the inferred values for fast radio bursts. The timescale of the radio flare in some cases can be extremely fast, of t...

  2. Investigation of Primordial Black Hole Bursts Using Interplanetary Network Gamma-ray Bursts

    Science.gov (United States)

    Ukwatta, T. N.; Hurley, K.; MacGibbon, J. H.; Svinkin, D. S.; Aptekar, R. L.; Golenetskii, S. V.; Frederiks, D. D.; Pal'shin, V. D.; Goldsten, J.; Boynton, W.; Kozyrev, A. S.; Rau, A.; von Kienlin, A.; Zhang, X.; Connaughton, V.; Yamaoka, K.; Ohno, M.; Ohmori, N.; Feroci, M.; Frontera, F.; Guidorzi, C.; Cline, T.; Gehrels, N.; Krimm, H. A.; McTiernan, J.

    2016-07-01

    The detection of a gamma-ray burst (GRB) in the solar neighborhood would have very important implications for GRB phenomenology. The leading theories for cosmological GRBs would not be able to explain such events. The final bursts of evaporating primordial black holes (PBHs), however, would be a natural explanation for local GRBs. We present a novel technique that can constrain the distance to GRBs using detections from widely separated, non-imaging spacecraft. This method can determine the actual distance to the burst if it is local. We applied this method to constrain distances to a sample of 36 short-duration GRBs detected by the Interplanetary Network (IPN) that show observational properties that are expected from PBH evaporations. These bursts have minimum possible distances in the 1013–1018 cm (7–105 au) range, which are consistent with the expected PBH energetics and with a possible origin in the solar neighborhood, although none of the bursts can be unambiguously demonstrated to be local. Assuming that these bursts are real PBH events, we estimate lower limits on the PBH burst evaporation rate in the solar neighborhood.

  3. On the bimodal distribution of gamma-ray bursts

    Science.gov (United States)

    Mao, Shude; Narayan, Ramesh; Piran, Tsvi

    1994-01-01

    Kouveliotou et al. recently confirmed that gamma-ray bursts are bimodal in duration. In this paper we compute the statistical properties of the short (less than or = 2 s) and long (greater than 2 s) bursts using a method of analysis that makes no assumption regarding the location of the bursts, whether in the Galaxy or at a cosmological distance. We find the 64 ms channel on Burst and Transient Source Experiment (BATSE) to be more sensitive to short bursts and the 1024 ms channel to be more sensitive to long bursts. We show that all the currently available data are consistent with the simple hypothesis that both short and long bursts have the same spatial distribution and that within each population the sources are standard candles. The rate of short bursts per unit volume is about 40% of the rate of long bursts. Although the durations of short and long gamma-ray bursts span several orders of magnitude and the total energy of a typical short burst is smaller than that of a typical long burst by a factor of about 20, surprisingly the peak luminosities of the two kinds of bursts are equal to within a factor of about 2.

  4. The short gamma-ray burst revolution

    International Nuclear Information System (INIS)

    Swift, a dedicated gamma-ray burst (GRB) satellite with ultrarapid slewing capability, and a suite of ground-based (ESO) telescopes have recently achieved a major breakthrough: detecting the first afterglows of short-duration GRBs. The faintness of these afterglows and the diversity of old and young host galaxies lend support to the emerging 'standard model', in which they are created during the merging of two compact objects. However, the afterglow light-curve properties and possible high-redshift origin of some short bursts suggests that more than one progenitor type may be involved. (orig.)

  5. Processor Reformats Data For Transmission In Bursts

    Science.gov (United States)

    Steele, Glen F.

    1991-01-01

    Data-processor-and-buffer electronic system receives audio signals digitized in first standard format at relatively low data rate, rearranges data for transmission in bursts in second standard format at relatively high rate, stores second-format bursts, and releases them at higher rate upon request. Conceived for asynchronous, one-way transmission of digitized speech in outer-space communications, concept of system applied in other digital communication systems in which data transmitted from low-rate sources to high-rate sinks not synchronized with sources.

  6. Distribution of whistler mode bursts at Venus

    Science.gov (United States)

    Scarf, F. L.; Jordan, K. F.; Russell, C. T.

    1987-01-01

    Several thousand impulsive whistler mode noise bursts were detected by the Pioneer Venus wave instrument during the first 10 seasons with nightside traversals at low altitudes. The altitude distribution for these events shows that essentially all of the bursts were detected when the orbiter was less than 2000 km above the planet, suggesting that the varying plasma conditions could not maintain coherent whistler mode field-aligned guidance over greater distances. Within the 2000-km range, the distribution of the number of events versus altitude shows that there are two distinct subregions. These results are interpreted in terms of two types of whistler mode propagation from sources below the ionosphere.

  7. A Shotgun Model for $\\gamma$ Ray Bursts

    CERN Document Server

    Heinz, S

    1999-01-01

    We propose that gamma ray bursts (GRBs) are produced by a shower of heavy blobs running into circumstellar material at highly relativistic speeds. The gamma ray emission is produced in the shocks these bullets drive into the surrounding medium. The short term variability seen in GRBs is set by the slowing-down time of the bullets while the overall duration of the burst is set by the lifetime of the central engine. A requirement of this model is that the ambient medium be dense, consistent with a strong stellar wind. In contrast to other external shock scenarios, the efficiency of the shock can be close to unity.

  8. Exploratory depth-of-burst experiments

    Energy Technology Data Exchange (ETDEWEB)

    Reichenbach, H.; Behrens, K. [Fraunhofer-Institut fuer Kurzzeitdynamik - Ernst-Mach-Institut (EMI), Freiburg im Breisgau (Germany); Kuhl, A. [R and D Associates, Los Angeles, CA (United States)

    1991-12-12

    This report describes the first small-scale explosion experiments with aerated grout (i.e., YTONG). Apart from data referring to crater depth and volume versus depth of burst (DOB), isobaric DOB curves in the range of 1.5 psi {le} p {le} 15 psi were established. The comparison with previous HOB values shows that the ground range to a given overpressure is considerably reduced with increasing depth of burst. The authors plan to continue the airblast investigations with different types of soil materials.

  9. Threats in Optical Burst Switched Network

    Directory of Open Access Journals (Sweden)

    P. Siva Subramanian

    2011-05-01

    Full Text Available Optical network is a viable network for future communication, which transmits data at an average rate of 50Tb/s. Optical Burst Switching is a trusted mechanism used for Optical network. There is a good amount of research done in the area of security in Optical networks. In addition, the issues related to physical network security has been dealt with respect to Optical networks. Our proposed work is intend to find the possible security threats that may happen in Optical Burst Switched Networks and the counter measures are examined separately. The NS-2 simulator with modified OBS patch is used to verify and validate the proposed mechanism

  10. Multi-level slug tests in highly permeable formations: 1. Modification of the Springer-Gelhar (SG) model

    Science.gov (United States)

    Zlotnik, V.A.; McGuire, V.L.

    1998-01-01

    A multi-level slug test model and a method for the evaluation of vertical profiles of hydraulic conductivity in highly permeable formations are developed. A double-packer system is employed to estimate local hydraulic conductivity. Depending on the formation and double-packer system parameters, the water level recovery in the tested well can exhibit a monotonic or oscillatory response. To discern information on aquifer properties from artifacts introduced by the measurement system, the theory of flow in an aquifer and a double-packer system is developed. The mathematical model incorporates features of the Springer and Gelhar (1991) model and reduces to the Bouwer and Rice (1976) model in a special case. The model involves equations of momentum and mass conservation for the double-packer system with quasi-steady well-aquifer interaction equations. The method is uniformly applicable for both monotonic and oscillatory well responses and can produce profiles of hydraulic conductivity for the tested well. The criterion is given to determine the type of well response for given slug test conditions.A multi-level slug test model and a method for the evaluation of vertical profiles of hydraulic conductivity in highly permeable formations are developed. A double-packer system is employed to estimate local hydraulic conductivity. Depending on the formation and double-packer system parameters, the water level recovery in the tested well can exhibit a monotonic or oscillatory response. To discern information on aquifer properties from artifacts introduced by the measurement system, the theory of flow in an aquifer and a double-packer system is developed. The mathematical model incorporates features of the Springer and Gelhar (1991) model and reduces to the Bouwer and Rice (1976) model in a special case. The model involves equations of momentum and mass conservation for the double-packer system with quasi-steady well-aquifer interaction equations. The method is uniformly

  11. Analytic benchmark solution to the linear, time-dependent multiregion isothermal slug flow fission-product plateout problem

    Energy Technology Data Exchange (ETDEWEB)

    Durkee, J.W. Jr.; Lee, C.E. (Texas A and M Univ., College Station (USA). Dept. of Nuclear Engineering)

    1984-01-01

    The analytic solution to the time-dependent, linear, convective-diffusion equation with radioactive decay is derived for axisymmetric slug flow through multiple materials in a cylindrical pipe under isothermal conditions. The Davidson variable metric minimization algorithm is used to determine the coupling coefficients: These solutions, which describe the transport of fission products in a flowing stream, are then used to determine the concentration of radioactive material deposited on a conduit wall and on the adsorber materials using a standard mass-transfer model.

  12. Onset of slugging criterion based on characteristics and stability analysis of transient one-dimensional two-phase flow equations of two-fluid model

    International Nuclear Information System (INIS)

    A two-step approach has been used to obtain a new onset of slug formation criterion for the stratified and nonstratified flows in horizontal pipes: (1) In the first step, a more general expression than the existing models for the onset of slug flow criterion has been derived from the analysis of singular points and neutral stability conditions of the transient one-dimensional two-phase flow equations of two-fluid model. (2) In the second step, introducing simplifications and incorporating a parameter into the general expression obtained in the first step to satisfy a number of physical conditions a priori specified, a new onset of slug flow criterion for horizontal pipes has been derived. Comparisons of the present model with the experimental data and existing theories show that the present model agrees very closely with the best existing model

  13. SLUG -- Stochastically Lighting Up Galaxies. III: A Suite of Tools for Simulated Photometry, Spectroscopy, and Bayesian Inference with Stochastic Stellar Populations

    CERN Document Server

    Krumholz, Mark R; da Silva, Robert L; Rendahl, Theodore; Parra, Jonathan

    2015-01-01

    Stellar population synthesis techniques for predicting the observable light emitted by a stellar population have extensive applications in numerous areas of astronomy. However, accurate predictions for small populations of young stars, such as those found in individual star clusters, star-forming dwarf galaxies, and small segments of spiral galaxies, require that the population be treated stochastically. Conversely, accurate deductions of the properties of such objects also requires consideration of stochasticity. Here we describe a comprehensive suite of modular, open-source software tools for tackling these related problems. These include: a greatly-enhanced version of the slug code introduced by da Silva et al. (2012), which computes spectra and photometry for stochastically- or deterministically-sampled stellar populations with nearly-arbitrary star formation histories, clustering properties, and initial mass functions; cloudy_slug, a tool that automatically couples slug-computed spectra with the cloudy r...

  14. ESTIMATION OF THE BURST LENGTH IN OBS NETWORKS

    Directory of Open Access Journals (Sweden)

    Pallavi S.

    2014-05-01

    Full Text Available This paper presents an overview of the optical burst switching (OBS and discusses the major components. In OBS, the length of the burst arriving at a particular node is unknown, and hence, node design is very complex. In OBS first control, packet is transmitted and reserve the path as in circuit switching, thereafter, the data bursts is transmitted. In this paper, a poisson arrival of packets is considered and estimation is made on the size of the burst length. The results presented in the paper clearly reveal that, the very large burst length is un-common. Therefore, most of the times, very short or average length burst is expected. Therefore it is concluded in this paper, buffering of burst at the contending nodes is a good option which increases the throughput and reduces the average delay. Finally, the buffering in conjunction with deflection of bursts will provide very effective solution.

  15. Power Enhancement Cavity for Burst-Mode Laser Pulses

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yun [ORNL

    2015-01-01

    We demonstrate a novel optical cavity scheme and locking method that can realize the power enhancement of picosecond UV laser pulses operating at a burst mode with arbitrary burst (macropulse) lengths and repetition rates.

  16. The future Gamma-Ray Burst Mission SVOM

    CERN Document Server

    Schanne, S; Wei, J; Zhang, S -N; Basa, S; Atteia, J -L; Barret, D; Claret, A; Cordier, B; Daigne, F; Godet, O; Götz, D; Mandrou, P

    2010-01-01

    We present the Space-based multi-band astronomical Variable Object Monitor (SVOM), a future satellite mission for Gamma-Ray Burst (GRB) studies, developed in cooperation between the Chinese National Space Agency (CNSA), the Chinese Academy of Science (CAS), the French Space Agency (CNES) and French research institutes. The scientific objectives of the SVOM GRB studies cover their classification (GRB diversity and unity of the model), their physics (particle acceleration and radiation mechanisms), their progenitors, cosmological studies (host galaxies, star formation history, re-ionization, cosmological parameters), and fundamental physics (origin of cosmic rays, Lorentz invariance, gravitational wave sources). From 2015 on, SVOM will provide fast and accurate localizations of all known types of GRB, and determine the temporal and spectral properties of the GRB emission, thanks to a set of four onboard instruments. The trigger system of the coded-mask telescope ECLAIRs onboard SVOM images the sky in the 4-120 ...

  17. The Spectral Sharpness Angle of Gamma-ray Bursts

    CERN Document Server

    Yu, Hoi-Fung; Greiner, Jochen; Sari, Re'em; Bhat, P Narayana; von Kienlin, Andreas; Paciesas, William S; Preece, Robert D

    2016-01-01

    We explain the results of Yu et al. (2015b) of the novel sharpness angle measurement to a large number of spectra obtained from the Fermi gamma-ray burst monitor. The sharpness angle is compared to the values obtained from various representative emission models: blackbody, single-electron synchrotron, synchrotron emission from a Maxwellian or power-law electron distribution. It is found that more than 91% of the high temporally and spectrally resolved spectra are inconsistent with any kind of optically thin synchrotron emission model alone. It is also found that the limiting case, a single temperature Maxwellian synchrotron function, can only contribute up to 58+23 -18% of the peak flux. These results show that even the sharpest but non-realistic case, the single-electron synchrotron function, cannot explain a large fraction of the observed spectra. Since any combination of physically possible synchrotron spectra added together will always further broaden the spectrum, emission mechanisms other than optically...

  18. Powerful Radio Burst Indicates New Astronomical Phenomenon

    Science.gov (United States)

    2007-09-01

    Astronomers studying archival data from an Australian radio telescope have discovered a powerful, short-lived burst of radio waves that they say indicates an entirely new type of astronomical phenomenon. Region of Strong Radio Burst Visible-light (negative greyscale) and radio (contours) image of Small Magellanic Cloud and area where burst originated. CREDIT: Lorimer et al., NRAO/AUI/NSF Click on image for high-resolution file ( 114 KB) "This burst appears to have originated from the distant Universe and may have been produced by an exotic event such as the collision of two neutron stars or the death throes of an evaporating black hole," said Duncan Lorimer, Assistant Professor of Physics at West Virginia University (WVU) and the National Radio Astronomy Observatory (NRAO). The research team led by Lorimer consists of Matthew Bailes of Swinburne University in Australia, Maura McLaughlin of WVU and NRAO, David Narkevic of WVU, and Fronefield Crawford of Franklin and Marshall College in Lancaster, Pennsylvania. The astronomers announced their findings in the September 27 issue of the online journal Science Express. The startling discovery came as WVU undergraduate student David Narkevic re-analyzed data from observations of the Small Magellanic Cloud made by the 210-foot Parkes radio telescope in Australia. The data came from a survey of the Magellanic Clouds that included 480 hours of observations. "This survey had sought to discover new pulsars, and the data already had been searched for the type of pulsating signals they produce," Lorimer said. "We re-examined the data, looking for bursts that, unlike the usual ones from pulsars, are not periodic," he added. The survey had covered the Magellanic Clouds, a pair of small galaxies in orbit around our own Milky Way Galaxy. Some 200,000 light-years from Earth, the Magellanic Clouds are prominent features in the Southern sky. Ironically, the new discovery is not part of these galaxies, but rather is much more distant

  19. Fast Radio Bursts: Searches, Sensitivities & Implications

    CERN Document Server

    Keane, E F

    2016-01-01

    Fast radio bursts (FRBs) are millisecond-duration transient signals discovered over the past decade. Here we describe the scientific usefulness of FRBs, consider ongoing work at the Parkes telescope, and examine some relevant search sensitivity and completeness considerations. We also look ahead to the results from ongoing and future planned studies in the field.

  20. Gamma-ray bursts at high redshift

    NARCIS (Netherlands)

    R.A.M.J. Wijers

    1999-01-01

    Gamma-ray bursts are much brighter than supernovae, and could therefore possibly probe the Universe to high redshift. The presently established GRB redshifts range from 0.83 to 5, and quite possibly even beyond that. Since most proposed mechanisms for GRB link them closely to deaths of massive stars

  1. Neutrino Balls and Gamma-Ray Bursts

    CERN Document Server

    Holdom, B

    1994-01-01

    We propose a mechanism by which the neutrino emission from a supernova-type explosion can be converted into a gamma-ray burst of total energy $\\sim 10^{50}$ ergs. This occurs naturally if the explosion is situated inside a ball of trapped neutrinos, which in turn may lie at a galactic core. There are possible unique signatures of this scenario.

  2. Methods and results of a search for gravitational waves associated with gamma-ray bursts using the GEO600, LIGO, and Virgo detectors

    OpenAIRE

    Aasi, J.; Abbott, B. P.; Abbott, R.; Abbott, T; Abernathy, M. R.; Acernese, F; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Gustafson, E. K.; Gustafson, R.; Ha, J.; Hall, E. D.

    2014-01-01

    In this paper we report on a search for short-duration gravitational wave bursts in the frequency range 64 Hz–1792 Hz associated with gamma-ray bursts (GRBs), using data from GEO 600 and one of the LIGO or Virgo detectors. We introduce the method of a linear search grid to analyze GRB events with large sky localization uncertainties, for example the localizations provided by the Fermi Gamma-ray Burst Monitor (GBM). Coherent searches for gravitational waves (GWs) can be computationally intensi...

  3. BurstMem: A High-Performance Burst Buffer System for Scientific Applications

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Teng [Auburn University, Auburn, Alabama; Oral, H Sarp [ORNL; Wang, Yandong [Auburn University, Auburn, Alabama; Settlemyer, Bradley W [ORNL; Atchley, Scott [ORNL; Yu, Weikuan [Auburn University, Auburn, Alabama

    2014-01-01

    The growth of computing power on large-scale sys- tems requires commensurate high-bandwidth I/O system. Many parallel file systems are designed to provide fast sustainable I/O in response to applications soaring requirements. To meet this need, a novel system is imperative to temporarily buffer the bursty I/O and gradually flush datasets to long-term parallel file systems. In this paper, we introduce the design of BurstMem, a high- performance burst buffer system. BurstMem provides a storage framework with efficient storage and communication manage- ment strategies. Our experiments demonstrate that BurstMem is able to speed up the I/O performance of scientific applications by up to 8.5 on leadership computer systems.

  4. $\\gamma$-ray Burst Positions from the ASM on RXTE

    CERN Document Server

    Bradt, H V; Bradt, Hale V.; Smith, Donald A.

    1999-01-01

    The RXTE/ASM has detected and positioned 14 confirmed GRB bursts (at this writing, Jan. 1999) including six whose positions were comunicated to the community 2 to 32 hours after the burst. Two of these latter bursts led to measurements of optical red shifts but one, despite an easily detected x-ray afterglow, produced no detectable optical or radio afterglow.

  5. AGILE Mini-Calorimeter gamma-gay burst catalog

    CERN Document Server

    Galli, M; Fuschino, F; Labanti, C; Argan, A; Barbiellini, G; Bulgarelli, A; Cattaneo, P W; Colafrancesco, S; Del Monte, E; Feroci, M; Giannotti, F; Giuliani, A; Longo, F; Mereghetti, S; Morselli, A; Pacciani, L; Pellizzoni, A; Pittori, C; Rapisarda, M; Rappoldi, A; Tavani, M; Trifoglio, M; Trois, A; Vercellone, S; Verrecchia, F

    2013-01-01

    The Mini-Calorimeter of the AGILE satellite can observe the high-energy part of gamma-ray bursts with good timing capability. We present the data of the 85 hard gamma-gay bursts observed by the Mini-Calorimeter since the launch (April 2007) until October 2009. We report the timing data for 84 and spectral data for 21 burst.

  6. IGR J17254-3257, a new bursting neutron star

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Falanga, M.; Kuulkers, E.;

    2007-01-01

    Aims. The study of the observational properties of uncommonly long bursts from low luminosity sources is important when investigating the transition from a hydrogen - rich bursting regime to a pure helium regime and from helium burning to carbon burning as predicted by current burst theories. On ...

  7. Burst Assembly Schemes and Performance Evaluation in Optical Burst Switching Networks

    Institute of Scientific and Technical Information of China (English)

    TANG Jian-jun; JI Yue-feng

    2004-01-01

    Several proposed assemble algorithms for Optical Burst Switching (OBS) network is described, and the feature relative merits is discussed and analyzed in this paper. The authors propose an assembly mechanism FAT where time threshold is fluctuating randomly to reduce continuous blocking rate. With network simulation, the basic performance of these assembly schemes is compared and analyzed. The results show that burst loss ratio and assembly delay of the proposed FAT mechanism is better than that of exist assemble mechanism.

  8. Improved adaptive-threshold burst assembly in optical burst switching networks

    Institute of Scientific and Technical Information of China (English)

    Jiuru Yang; Gang Wang; Shilou Jia

    2007-01-01

    An improved adaptive-threshold burst assembly algorithm is proposed to alleviate the limitation of conventional assembly schemes on data loss and delay. The algorithm will adjust the values of assembly factors according to variant traffic regions. And the simulation results show that, by using the adaptive-factor adaptive assembly scheme, the performance of networks is extensively enhanced in terms of burst loss probability and average queuing delay.

  9. Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo

    Directory of Open Access Journals (Sweden)

    Anastassiou Dimitris

    2011-12-01

    Full Text Available Abstract Background The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT. Methods We used xenograft models of human cancer cells in immunocompromised mice, profiling the harvested tumors separately with species-specific probes and computationally analyzing the results. Results Here we show that human cancer cells express in vivo a precise multi-cancer invasion-associated gene expression signature that prominently includes many EMT markers, among them the transcription factor Slug, fibronectin, and α-SMA. We found that human, but not mouse, cells express the signature and Slug is the only upregulated EMT-inducing transcription factor. The signature is also present in samples from many publicly available cancer gene expression datasets, suggesting that it is produced by the cancer cells themselves in multiple cancer types, including nonepithelial cancers such as neuroblastoma. Furthermore, we found that the presence of the signature in human xenografted cells was associated with a downregulation of adipocyte markers in the mouse tissue adjacent to the invasive tumor, suggesting that the signature is triggered by contextual microenvironmental interactions when the cancer cells encounter adipocytes, as previously reported. Conclusions The known, precise and consistent gene composition of this cancer mesenchymal transition signature, particularly when combined with simultaneous analysis of the adjacent microenvironment, provides unique opportunities for shedding light on the underlying mechanisms of cancer invasiveness as well as identifying potential diagnostic markers and targets for metastasis-inhibiting therapeutics.

  10. Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug

    Science.gov (United States)

    Tamminen, J A; Parviainen, V; Rönty, M; Wohl, A P; Murray, L; Joenväärä, S; Varjosalo, M; Leppäranta, O; Ritvos, O; Sengle, G; Renkonen, R; Myllärniemi, M; Koli, K

    2013-01-01

    Malignant mesothelioma is a form of cancer that is highly resistant to conventional cancer therapy for which no major therapeutic advances have been introduced. Here, we identify gremlin-1, a known bone morphogenetic protein inhibitor crucial for embryonic development, as a potential therapeutic target for mesothelioma. We found high expression levels of gremlin-1 in the mesothelioma tumor tissue, as well as in primary mesothelioma cells cultured from pleural effusion samples. Downregulation of gremlin-1 expression by siRNA-mediated silencing in a mesothelioma cell line inhibited cell proliferation. This was associated with downregulation of the transcription factor slug as well as mesenchymal proteins linked to cancer epithelial-to-mesenchymal transition. Further, resistance to paclitaxel-induced cell death was associated with high gremlin-1 and slug expression. Treatment of gremlin-1-silenced mesothelioma cells with paclitaxel or pemetrexed resulted in efficient loss of cell survival. Finally, our data suggest that concomitant upregulation of fibrillin-2 in mesothelioma provides a mechanism for extracellular localization of gremlin-1 to the tumor microenvironment. This was supported by the demonstration of interactions between gremlin-1, and fibrillin-1 and -2 peptides as well as by colocalization of gremlin-1 to fibrillin microfibrils in cells and tumor tissue samples. Our data suggest that gremlin-1 is also a potential target for overcoming drug resistance in mesothelioma. PMID:23978876

  11. Measurment of gas-liquid two-phase slug flow with a Venturi meter based on blind source separation☆

    Institute of Scientific and Technical Information of China (English)

    Weiwei Wang; Xiao Liang; Mingzhu Zhang

    2015-01-01

    We propose a novel flow measurement method for gas–liquid two-phase slug flow by using the blind source sep-aration technique. The flow measurement model is established based on the fluctuation characteristics of differ-ential pressure (DP) signals measured from a Venturi meter. It is demonstrated that DP signals of two-phase flow are a linear mixture of DP signals of single phase fluids. The measurement model is a combination of throttle re-lationship and blind source separation model. In addition, we estimate the mixture matrix using the independent component analysis (ICA) technique. The mixture matrix could be described using the variances of two DP sig-nals acquired from two Venturi meters. The validity of the proposed model was tested in the gas–liquid two-phase flow loop facility. Experimental results showed that for most slug flow the relative error is within 10%. We also find that the mixture matrix is beneficial to investigate the flow mechanism of gas–liquid two-phase flow.

  12. SVOM Gamma Ray Monitor

    CERN Document Server

    Dong, Yongwei; Li, Yanguo; Zhang, Yongjie; Zhang, Shuangnan

    2009-01-01

    The Space-based multi-band astronomical Variable Object Monitor (SVOM) mission is dedicated to the detection, localization and broad-band study of Gamma-Ray Bursts (GRBs) and other high-energy transient phenomena. The Gamma Ray Monitor (GRM) onboard is designed to observe the GRBs up to 5 MeV. With this instrument one of the key GRB parameter, Epeak, can be easily measured in the hard x-ray band. It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  13. SVOM gamma ray monitor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The space-based multi-band astronomical Variable Object Monitor(SVOM) mission is dedicated to the detection,localization and broad-band study of gamma-ray bursts(GRBs) and other high-energy transient phenomena.The gamma ray monitor(GRM) onboard is designed to observe GRBs up to 5 MeV.With this instrument,one of the key GRB parameters,Epeak,can be easily measured in the hard X-ray band.It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  14. Investigation of Primordial Black Hole Bursts using Interplanetary Network Gamma-ray Bursts

    CERN Document Server

    Ukwatta, T N; MacGibbon, J H; Svinkin, D S; Aptekar, R L; Golenetskii, S V; Frederiks, D D; Pal'shin, V D; Goldsten, J; Boynton, W; Fellows, C; Harshman, K; Mitrofanov, I G; Golovin, D V; Kozyrev, A S; Litvak, M L; Sanin, A B; Rau, A; Kienlin, A; Zhang, X; Briggs, M S; Connaughton, V; Meegan, C; Yamaoka, K; Fukazawa, Y; Ohno, M; Ohmori, N; Takahashi, T; Tashiro, M; Terada, Y; Murakami, T; Makishima, K; Feroci, M; Frontera, F; Guidorzi, C; Barthelmy, S; Cline, T; Gehrels, N; Cummings, J; Krimm, H A; Smith, D M; McTiernan, J

    2015-01-01

    The detection of a gamma-ray burst (GRB) in the solar neighborhood would have very important implications for GRB phenomenology. The leading theories for cosmological GRBs would not be able to explain such events. The final bursts of evaporating Primordial Black Holes (PBHs), however, would be a natural explanation for local GRBs. We present a novel technique that can constrain the minimum distance to gamma-ray bursts using detections from widely separated spacecraft. We applied this method to constrain distances to a sample of 36 short duration GRBs detected by the Interplanetary Network (IPN) that show observational properties that are expected from PBH evaporations. These bursts have minimum possible distances in the 10^13-10^18 cm (7-10^5 AU) range, consistent with the expected PBH energetics and with a possible origin in the solar neighborhood, although none of the bursts can be unambiguously demonstrated to be local. Assuming these bursts are real PBH events, we estimate for the first time lower limits ...

  15. Powerful Radio Burst Indicates New Astronomical Phenomenon

    Science.gov (United States)

    2007-09-01

    Astronomers studying archival data from an Australian radio telescope have discovered a powerful, short-lived burst of radio waves that they say indicates an entirely new type of astronomical phenomenon. Region of Strong Radio Burst Visible-light (negative greyscale) and radio (contours) image of Small Magellanic Cloud and area where burst originated. CREDIT: Lorimer et al., NRAO/AUI/NSF Click on image for high-resolution file ( 114 KB) "This burst appears to have originated from the distant Universe and may have been produced by an exotic event such as the collision of two neutron stars or the death throes of an evaporating black hole," said Duncan Lorimer, Assistant Professor of Physics at West Virginia University (WVU) and the National Radio Astronomy Observatory (NRAO). The research team led by Lorimer consists of Matthew Bailes of Swinburne University in Australia, Maura McLaughlin of WVU and NRAO, David Narkevic of WVU, and Fronefield Crawford of Franklin and Marshall College in Lancaster, Pennsylvania. The astronomers announced their findings in the September 27 issue of the online journal Science Express. The startling discovery came as WVU undergraduate student David Narkevic re-analyzed data from observations of the Small Magellanic Cloud made by the 210-foot Parkes radio telescope in Australia. The data came from a survey of the Magellanic Clouds that included 480 hours of observations. "This survey had sought to discover new pulsars, and the data already had been searched for the type of pulsating signals they produce," Lorimer said. "We re-examined the data, looking for bursts that, unlike the usual ones from pulsars, are not periodic," he added. The survey had covered the Magellanic Clouds, a pair of small galaxies in orbit around our own Milky Way Galaxy. Some 200,000 light-years from Earth, the Magellanic Clouds are prominent features in the Southern sky. Ironically, the new discovery is not part of these galaxies, but rather is much more distant

  16. Phantom bursting is highly sensitive to noise and unlikely to account for slow bursting in beta-cells

    DEFF Research Database (Denmark)

    Pedersen, Morten Gram

    2007-01-01

    Pancreatic beta-cells show bursting electrical activity with a wide range of burst periods ranging from a few seconds, often seen in isolated cells, over tens of seconds (medium bursting), usually observed in intact islets, to several minutes. The phantom burster model [Bertram, R., Previte, J., ...

  17. The Decay of Optical Emission Form the Gamma-Ray Burst GRB 970228

    Science.gov (United States)

    Galama, T.; Groot, P. J.; vanParadijs, J.; Kouvellotou, C.; Robinson, C. R.; Fishmans, G. J.; Meegan, C. A.; Sahu, K. C.; Livio, M.; Petro, L.

    1997-01-01

    The origin of gamma-ray bursts has been one of the great unsolved mysteries in high-energy astrophysics for almost 30 years. The recent discovery of fading sources at X-ray and optical wave-lengths coincident with the location of the gamma-ray burst GRB970228 therefore provides an unprecedented opportunity to probe the nature of these high-energy events. The optical counterpart appears to be a transient point source embedded in a region of extended nebulosity, the latter having been tentatively identified as a high-redshift galaxy. This would seem to favour models that place gamma-ray bursts at cosmological distances, although a range of mechanisms for producing the bursts is still allowed. A crucial piece of information for distinguishing between such models is how the brightness of the optical counterpart evolves with time. Here we re-evaluate the existing photometry of the optical counterpart of GRB970228 to construct an optical light curve for the transient event. We find that between 21 hours and six days after the burst, the R-band brightness decreased by a factor of approx. 50, with any subsequent decrease in brightness occurring at a much slower rate. As the point source faded, it also became redder. The initial behaviour of the source appears to be consistent with the 'fireball' model, in which the burst results from the merger of two neutron stars, but the subsequent decrease in the rate of fading may prove harder to explain. The gamma-ray burst of 28 February 1997, detected with the Gamma-Ray Burst Monitor on board the BeppoSAX satellite, and located with an approx. 3 feet radius position with the Wide Field Camera on the same satellite, was the first for which a fading X-ray and optical counterpart were discovered. The optical Counterpart was discovered from a comparison of V- and I-band images taken with the William Herschel Telescope (WHT) on February 28.99 UT, and the Isaac Newton Telescope (INT; V band) and the WHT (I band) on March 8.8 uT.

  18. Gravitational-wave bursts with memory and experimental prospects

    International Nuclear Information System (INIS)

    The authors show that for any kind of detector the best way to search for a ''bursts with memory'' (BWM) gravitation wave is to integrate up the signal for an integration time tau-circumflex approx.= 1/fsub(opt), where fsub(opt) is the frequency at which the detector has optimal amplitude sensitivity to ordinary bursts (bursts with memory). In such a search the sensitivity to BWM with duration Δt < or approx. 1/fsub(opt) is independent of the burst duration Δt and is approximately equal to the sensitivity to ordinary bursts one cycle long with frequency fsub(opt). (author)

  19. X-Ray Observations of Gamma-Ray Burst Afterglows

    OpenAIRE

    Frontera, Filippo

    2004-01-01

    The discovery by the BeppoSAX satellite of X-ray afterglow emission from the gamma-ray burst which occurred on 28 February 1997 produced a revolution in our knowledge of the gamma-ray burst phenomenon. Along with the discovery of X-ray afterglows, the optical afterglows of gamma-ray bursts were discovered and the distance issue was settled, at least for long $\\gamma$-ray bursts. The 30 year mystery of the gamma-ray burst phenomenon is now on the way to solution. Here I rewiew the observationa...

  20. Rock Burst Mechanics: Insight from Physical and Mathematical Modelling

    OpenAIRE

    Vacek, J.; J. Chocholoušová

    2008-01-01

    Rock burst processes in mines are studied by many groups active in the field of geomechanics. Physical and mathematical modelling can be used to better understand the phenomena and mechanisms involved in the bursts. In the present paper we describe both physical and mathematical models of a rock burst occurring in a gallery of a coal mine.For rock bursts (also called bumps) to occur, the rock has to possess certain particular rock burst properties leading to accumulation of energy and the pot...

  1. GeV emission from Gamma Ray Bursts: a radiative fireball?

    CERN Document Server

    Ghisellini, G; Nava, L

    2009-01-01

    We study the emission observed at energies >100 MeV of 11 Gamma Ray Bursts (GRBs) detected by the Fermi Large Area Telescope (LAT) until October 2009. The GeV emission has three main properties: (i) its duration is longer than the duration of the softer emission detected by the Gamma Burst Monitor (GBM) onboard Fermi; (ii) its spectrum is consistent with F(v) propto v^(-1) and does not show strong spectral evolution; (iii) for the brighest bursts, the flux detected by the LAT decays as a power law with a typical slope: t^(-1.5). We argue that the observed >0.1 GeV flux can be interpreted as afterglow emission shortly following the start of the prompt emission as seen at smaller frequencies. The decay slope is what expected if the fireball emission is produced in the radiative regime, i.e. all dissipated energy is radiated away. We also argue that the detectability in the GeV energy range depends on the bulk Lorentz factor Gamma of the bursts, being strongly favoured in the case of large Gamma. This implies th...

  2. High Energy Observations of XRF 030723: Evidence for an Off-axis Gamma-Ray Burst?

    CERN Document Server

    Butler, N R; Suzuki, M; Kawai, N; Lamb, D Q; Graziani, C; Donaghy, T Q; Dullighan, A; Vanderspek, R; Crew, G B; Ford, P; Ricker, G; Atteia, J L; Yoshida, A; Shirasaki, Y; Tamagawa, T; Torii, K; Matsuoka, M; Fenimore, E E; Galassi, M; Doty, J; Villaseñor, J D; Prigozhin, G Y; Jernigan, J G; Barraud, C; Boër, M; Dezalay, J P; Olive, J F; Hurley, K; Levine, A; Martel, F; Morgan, E; Woosley, S E; Cline, T; Braga, J; Manchanda, R K; Pizzichini, G

    2004-01-01

    We report High Energy Transient Explorer 2 (HETE-2) Wide Field X-ray Monitor/French Gamma Telescope observations of XRF030723 along with observations of the XRF afterglow made using the 6.5m Magellan Clay telescope and the Chandra X-ray Observatory. The observed peak energy E_pk_obs of the nu F_nu burst spectrum is found to lie within (or below) the WXM 2-25 keV passband at 98.5% confidence, and no counts are detected above 30 keV. Our best fit value is E_pk_obs=8.4+3.5/-3.4 keV. The ratio of X-ray to Gamma-ray flux for the burst follows a correlation found for GRBs observed with HETE-2, and the duration of the burst is similar to that typical of long-duration GRBs. If we require that the burst isotropic equivalent energy E_iso and E_pk_rest satisfy the relation discovered by Amati et al. (2002), a redshift of z=0.38+0.36/-0.18 can be determined, in agreement with constraints determined from optical observations. We are able to fit the X-ray afterglow spectrum and to measure its temporal fade. Although the be...

  3. Adaptive Kalman Filter Based on Adjustable Sampling Interval in Burst Detection for Water Distribution System

    Directory of Open Access Journals (Sweden)

    Doo Yong Choi

    2016-04-01

    Full Text Available Rapid detection of bursts and leaks in water distribution systems (WDSs can reduce the social and economic costs incurred through direct loss of water into the ground, additional energy demand for water supply, and service interruptions. Many real-time burst detection models have been developed in accordance with the use of supervisory control and data acquisition (SCADA systems and the establishment of district meter areas (DMAs. Nonetheless, no consideration has been given to how frequently a flow meter measures and transmits data for predicting breaks and leaks in pipes. This paper analyzes the effect of sampling interval when an adaptive Kalman filter is used for detecting bursts in a WDS. A new sampling algorithm is presented that adjusts the sampling interval depending on the normalized residuals of flow after filtering. The proposed algorithm is applied to a virtual sinusoidal flow curve and real DMA flow data obtained from Jeongeup city in South Korea. The simulation results prove that the self-adjusting algorithm for determining the sampling interval is efficient and maintains reasonable accuracy in burst detection. The proposed sampling method has a significant potential for water utilities to build and operate real-time DMA monitoring systems combined with smart customer metering systems.

  4. Time resolved spectroscopy of SGR J1550-5418 bursts detected with Fermi/GBM

    CERN Document Server

    Younes, G; van der Horst, A J; Baring, M G; Granot, J; Watts, A L; Bhat, P N; Collazzi, A; Gehrels, N; Gorgone, N; Gogus, E; Gruber, D; Grunblatt, S; Huppenkothen, D; Kaneko, Y; von Kienlin, A; van der Klis, M; Lin, L; Mcenery, J; van Putten, T; Wijers, R A M J

    2014-01-01

    We report on time-resolved spectroscopy of the 63 brightest bursts of SGR J1550-5418, detected with Fermi/Gamma-ray Burst Monitor during its 2008-2009 intense bursting episode. We performed spectral analysis down to 4 ms time-scales, to characterize the spectral evolution of the bursts. Using a Comptonized model, we find that the peak energy, E_peak, anti-correlates with flux, while the low-energy photon index remains constant at -0.8 up to a flux limit F~10^-5 erg s-1 cm-2. Above this flux value the E_peak-flux correlation changes sign, and the index positively correlates with flux reaching 1 at the highest fluxes. Using a two black-body model, we find that the areas and fluxes of the two emitting regions correlate positively. Further, we study here for the first time, the evolution of the temperatures and areas as a function of flux. We find that the area-kT relation follows lines of constant luminosity at the lowest fluxes, R^2 \\propto kT^-4, with a break at higher fluxes ($F>10^-5.5 erg s-1 cm-2). The are...

  5. Long Type I X-ray Bursts and Neutron Star Interior Physics

    CERN Document Server

    Cumming, A; in 't Zand, J J M; Page, D; Cumming, Andrew; Macbeth, Jared; Page, Dany

    2005-01-01

    Superbursts are very energetic Type I X-ray bursts discovered in recent years by long term monitoring of X-ray bursters, believed to be due to unstable ignition of carbon in the deep ocean of the neutron star. A number of "intermediate duration" bursts have also been observed, probably associated with ignition of a thick helium layer. We investigate the sensitivity of these long X-ray bursts to the thermal profile of the neutron star crust and core. We first compare cooling models of superburst lightcurves with observations, and derive constraints on the ignition mass and energy release, and then calculate ignition models for superbursts and pure helium bursts, and compare to observations. The superburst lightcurves and ignition models imply that the carbon mass fraction is approximately 20% or greater in the fuel layer, constraining models of carbon production. However, the most important result is that when Cooper pairing neutrino emission is included in the crust, the temperature is too low to support unst...

  6. An Analysis of Burst Disc Pressure Instability

    Energy Technology Data Exchange (ETDEWEB)

    S. L. Robinson; B. C. Odegard, Jr.; N. r. Moody; S. H. Goods

    2000-06-01

    During the development stage of the 1X Acorn burst disc, burst pressure test results exhibited an unexpected increase of 8 to 14% over times of 90--100 days from initial fabrication. This increase is a concern where design constraints require stability. The disc material, 316L stainless steel sheet, is formed to a dome-like geometry and scored to produce a thin-walled, high-strength ligament. The fracture events controlling burst occur in that ligament. Thus it has been characterized both for tensile properties and microstructure through nanoindentation, magnetic measurements, optical and transmission electron microscopy. These results compare favorably with finite element simulation of the properties of the ligament. The ligament exhibits a highly heterogeneous microstructure; its small volume and microstructural heterogeneity make it difficult to identify which microstructural feature controls fracture and hence burst pressure. Bulk mechanical test specimens were fabricated to emulate mid-ligament properties, and aged at both room and elevated temperatures to characterize and accelerate the temporal behavior of the burst disc. Property changes included yield and ultimate tensile strength increases, and fracture strain decreases with aging. Specimens were subjected to a reversion anneal identical to that given the burst disc to eliminate the martensite phase formed during rolling. Reversion-annealed samples exhibited no change in properties in room temperature or accelerated aging, showing that the reversion-anneal eliminated the aging phenomenon. Aging was analyzed in terms of diffusion controlled precipitate growth kinetics, showing that carbon migration to dislocations is consistent with the strength increases. A vacancy-assisted diffusion mechanism for carbon transport is proposed, giving rise to rapid aging, which replaces interstitial carbon diffusion until excess vacancies from deformation are consumed. Mechanical activation parameters in stress relaxation

  7. Susceptibility of the eggs of the field slug Deroceras reticulatum to contact with pesticides and substances of biological origin on artificial soil

    NARCIS (Netherlands)

    Iglesias, J.; Castillejo, J.; Ester, A.; Castro, R.; Lombardia, M.J.

    2002-01-01

    The toxicity of 14 substances, including a number of pesticides, to the eggs of the pest slug Deroceras reticulatum was determined in laboratory experiments. Eggs were kept in contact with a precisely defined artificial soil to which a range of concentrations of the test substances had been applied.

  8. Gas-liquid two-phase severe slugging in a pipeline-riser system with S-shaped flexible riser: Experiments and modeling

    Science.gov (United States)

    Li, Nailiang; Guo, Liejin; Li, Wensheng

    2013-07-01

    The objective of the present work is to investigate the air-water two-phase flow patterns in pipeline-riser system with an S-shaped flexible riser. The test loop with 50 mm ID consists of a horizontal pipeline with 114 m in length, a downward inclined section with 16 m in length, and an S-shaped flexible riser with 24 m in height when downward section inclined at -2° with respective to the horizontal. The inclination angle of the downward section varied from -2° to -5°. The liquid superficial velocity ranged from 0.03 to 1.5 m/s, and the gas superficial velocity from 0.4 to 6.0 m/s. Identification and characterization of flow regimes were attained by pressure at riser-base and liquid holdup at riser top. Severe slugging I, severe slugging II, transition flow and stable flows are observed to exist. Flow pattern maps for each declination are presented and the transition criteria are proposed. It's found that as higher liquid and gas velocity is required for the transition of the flow in the pipeline from stratified to intermittent with increasing the declination angle, severe slugging was observed to occur over a wilder range of flow conditions. The effect of riser geometry and separator pressure on the occurrence of the flow patterns was also examined. It shows that the S-bend tends to suppress the initiation of severe slugging.

  9. Depletion of Serotonin Selectively Impairs Short-Term Memory without Affecting Long-Term Memory in Odor Learning in the Terrestrial Slug "Limax Valentianus"

    Science.gov (United States)

    Santa, Tomofumi; Kirino, Yutaka; Watanabe, Satoshi; Shirahata, Takaaki; Tsunoda, Makoto

    2006-01-01

    The terrestrial slug "Limax" is able to acquire short-term and long-term memories during aversive odor-taste associative learning. We investigated the effect of the selective serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) on memory. Behavioral studies indicated that 5,7-DHT impaired short-term memory but not long-term memory. HPLC…

  10. Subsea hydrocarbon mixing transportation section of the pipeline slug flow serious problem%海底油气混输管道严重段塞流问题

    Institute of Scientific and Technical Information of China (English)

    张松; 王迪; 段瑞溪

    2015-01-01

    严重段塞流是海底油气混输管道常见问题,本文分析了段塞流产生的机理与危害,严重段塞流有四个过程,段塞流对生产设施造成冲击并对下游生产设施造成很大的波动;总结了七种严重段塞流控制方法的原理,分析了各种控制方法在海洋油气田中的适用性。%Severe slugging flow is mixed seabe d oil and gas pipelines frequentl questions.This paper analyzes the mechanism and harm resulting slug flow,slug flow has four serious process,slug flow impact on the production facilities and downstream production facilities caused great fluctuations;summarizes the plug flow control method of the seven principles of severe analyzed the applicability of various control methods of oil and gas fields in the sea.

  11. On associating Fast Radio Bursts with afterglows

    CERN Document Server

    Vedantham, H K; Mooley, K; Frail, D; Hallinan, G; Kulkarni, S R

    2016-01-01

    A radio source that faded over 6 days, with a redshift $z\\approx0.5$ host, has been identified by Keane et al. (2016) as the transient afterglow to a Fast Radio Burst (FRB 150418). We report follow-up radio and optical observations of the afterglow candidate, and find a source that is consistent with an active galactic nucleus (AGN). If the afterglow-candidate is nonetheless a prototypical FRB afterglow, existing surveys limit the fraction of FRBs that produce afterglows to 0.25 for modulation-index $m=\\Delta S/\\bar{S}\\geq0.7$, and 0.07 for $m\\geq1$, at 95\\% confidence. Afterglow associations with the barrage of bursts expected from future FRB surveys must satisfy constraints on the afterglow rate set by state of the art slow-transient surveys.

  12. The Supernova -- Gamma-Ray Burst Connection

    CERN Document Server

    Woosley, S E

    2006-01-01

    Observations show that at least some gamma-ray bursts (GRBs) happen simultaneously with core-collapse supernovae (SNe), thus linking by a common thread nature's two grandest explosions. We review here the growing evidence for and theoretical implications of this association, and conclude that most long-duration soft-spectrum GRBs are accompanied by massive stellar explosions (GRB-SNe). The kinetic energy and luminosity of well-studied GRB-SNe appear to be greater than those of ordinary SNe, but evidence exists, even in a limited sample, for considerable diversity. The existing sample also suggests that most of the energy in the explosion is contained in nonrelativistic ejecta (producing the supernova) rather than in the relativistic jets responsible for making the burst and its afterglow. Neither all SNe, nor even all SNe of Type Ibc produce GRBs. The degree of differential rotation in the collapsing iron core of massive stars when they die may be what makes the difference.

  13. Bursting behaviours in cascaded stimulated Brillouin scattering

    Institute of Scientific and Technical Information of China (English)

    Liu Zhan-Jun; He Xian-Tu; Zheng Chun-Yang; Wang Yu-Gang

    2012-01-01

    Stimulated Brillouin scattering is studied by numerically solving the Vlasov-Maxwell system.A cascade of stimulated Brillouin scattering can occur when a linearly polarized laser pulse propagates in a plasma.It is found that a stimulated Brillouin scattering cascade can reduce the scattering and increase the transmission of light,as well as introduce a bursting behaviour in the evolution of the laser-plasma interaction.The bursting time in the reflectivity is found to be less than half the ion acoustic period.The ion temperature can affect the stimulated Brillouin scattering cascade,which can repeat several times at low ion temperatures and can be completely eliminated at high ion temperatures.For stimulated Brillouin scattering saturation,higher-harmonic generation and wave-wave interaction of the excited ion acoustic waves can restrict the amplitude of the latter.In addition,stimulated Brillouin scattering cascade can restrict the amplitude of the scattered light.

  14. Are gamma-ray bursts cosmological?

    CERN Document Server

    Horvath, I

    2015-01-01

    Gamma-ray burst sources are distributed with a high level of isotropy, which is compatible with either a cosmological origin or an extended Galactic halo origin. The brightness distribution is another indicator used to characterize the spatial distribution in distance. In this paper the author discusses detailed fits of the BATSE gamma-ray burst peak-flux distributions with Friedmann models taking into account possible density evolution and standard candle luminosity functions. A chi-square analysis is used to estimate the goodness of the fits and the author derives the significance level of limits on the density evolution and luminosity function parameters. Cosmological models provide a good fit over a range of parameter space which is physically reasonable

  15. Coherence resonance in bursting neural networks

    Science.gov (United States)

    Kim, June Hoan; Lee, Ho Jun; Min, Cheol Hong; Lee, Kyoung J.

    2015-10-01

    Synchronized neural bursts are one of the most noticeable dynamic features of neural networks, being essential for various phenomena in neuroscience, yet their complex dynamics are not well understood. With extrinsic electrical and optical manipulations on cultured neural networks, we demonstrate that the regularity (or randomness) of burst sequences is in many cases determined by a (few) low-dimensional attractor(s) working under strong neural noise. Moreover, there is an optimal level of noise strength at which the regularity of the interburst interval sequence becomes maximal—a phenomenon of coherence resonance. The experimental observations are successfully reproduced through computer simulations on a well-established neural network model, suggesting that the same phenomena may occur in many in vivo as well as in vitro neural networks.

  16. Bursts of activity in collective cell migration

    CERN Document Server

    Chepizhko, Oleksandr; Mastrapasqua, Eleonora; Nourazar, Mehdi; Ascagni, Miriam; Sugni, Michela; Fascio, Umberto; Leggio, Livio; Malinverno, Chiara; Scita, Giorgio; Santucci, Stephane; Alava, Mikko J; Zapperi, Stefano; La Porta, Caterina A M

    2016-01-01

    Dense monolayers of living cells display intriguing relaxation dynamics, reminiscent of soft and glassy materials close to the jamming transition, and migrate collectively when space is available, as in wound healing or in cancer invasion. Here we show that collective cell migration occurs in bursts that are similar to those recorded in the propagation of cracks, fluid fronts in porous media and ferromagnetic domain walls. In analogy with these systems, the distribution of activity bursts displays scaling laws that are universal in different cell types and for cells moving on different substrates. The main features of the invasion dynamics are quantitatively captured by a model of interacting active particles moving in a disordered landscape. Our results illustrate that collective motion of living cells is analogous to the corresponding dynamics in driven, but inanimate, systems.

  17. Burst Detector X-Ray IIR

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The Burst Detector X-Ray (BDX) instrument for the Block IIR series of Global Positioning System satellites is described. The BDX instrument can locate and characterize exoatmospheric nuclear detonations by using four sensors consisting of sets of filters over silicon diodes to detect x rays of various energies from the burst. On the BDX-IIR, a fifth sensor with a response spanning those of the other sensors confirms coincidences among the four main channels. The mechanical and electronic features of the BDX-IIR and its sensors are described. The calibrations and the system tests used in flight are presented. The commands for the BDX-IIR are given. The messages sent from the BDX-IIR are described in detail.

  18. Environmental Effects of Gamma Ray Bursts

    International Nuclear Information System (INIS)

    Gamma rays bursts, coming from very massive stars, are the most powerful explosions in our Universe. Some authors have linked them to some of the climatic changes and consequent biological mass extinctions of the Phanerozoic eon. However, the consequences of their direct impact on primitive Earth, is today a hot topic of debate. On the other hand, it is usually assumed that they were more common in earlier stages of our galaxy. So it is important to evaluate its potential effects on terrestrial paleoenvironments. We outline some simple models to estimate their influence mainly on the primordial atmospheric chemistry of Earth and on the climate in general. To do that, we consider different scenarios where the atmospheric composition diverges substantially from the atmosphere today, and compute the evolution of principal chemical species under the intense radiational stress of a gamma ray burst. Furthermore, the possible impact on the isotopic composition, geochemistry and the biosphere are mentioned in general way

  19. Coherence resonance in bursting neural networks.

    Science.gov (United States)

    Kim, June Hoan; Lee, Ho Jun; Min, Cheol Hong; Lee, Kyoung J

    2015-10-01

    Synchronized neural bursts are one of the most noticeable dynamic features of neural networks, being essential for various phenomena in neuroscience, yet their complex dynamics are not well understood. With extrinsic electrical and optical manipulations on cultured neural networks, we demonstrate that the regularity (or randomness) of burst sequences is in many cases determined by a (few) low-dimensional attractor(s) working under strong neural noise. Moreover, there is an optimal level of noise strength at which the regularity of the interburst interval sequence becomes maximal-a phenomenon of coherence resonance. The experimental observations are successfully reproduced through computer simulations on a well-established neural network model, suggesting that the same phenomena may occur in many in vivo as well as in vitro neural networks.

  20. 矩形截面螺旋通道内弹状流的流动特性%Flow characteristics of slug flow in helical rectangular channel

    Institute of Scientific and Technical Information of China (English)

    刘献飞; 夏国栋; 杨光

    2014-01-01

    Experimental investigations on slug flow were carried out in horizontal helical rectangular channel by using high speed flow visualization. Evolution of slug in the whole helical rectangular channel was presented and the fine features of slug flow in different positions were illustrated. The slug characteristics changed along the axial direction due to the combined effects of gravitational and centrifugal force. Based on the experimental data, slug velocity, slug frequency and length distribution in different positions were given. The present topography measurement illustrated the evolution features of liquid film thickness, which was determined by the effect of centrifugal force and gravity. Liquid film falling velocity decreased as the slug moved upward and was visibly increasing in the downward flow.%对水平放置矩形截面螺旋通道内弹状流的流动特性进行了实验研究。通过实验获得了不同周角下的气弹演变过程和局部流动特征,结果表明,其流动特性会随着螺旋周角位置的变化而变化。根据实验数据分析发现,同一工况下,不同转角气弹的运动速度、频率和长度分布不尽相同。重力和离心力的相对大小决定着内外壁面液膜的厚度,给出了同一条件下,不同时刻的液膜厚度的演变过程。最后对下降液膜的运动速度展开了分析研究,在螺旋上升过程中,液膜下降速度逐渐减小,在螺旋下降段,液膜速度明显增大。

  1. GAMMA-RAY BURSTS, NEW COSMOLOGICAL BEACONS

    Directory of Open Access Journals (Sweden)

    V. Avila-Reese

    2009-01-01

    Full Text Available Long Gamma-Ray Bursts (GRBs are the brightest electromagnetic explosions in the Universe, associated to the death of massive stars. As such, GRBs are potential tracers of the evolution of the cosmic massive star formation, metallicity, and Initial Mass Function. GRBs also proved to be appealing cosmological distance indicators. This opens a unique opportunity to constrain the cosmic expansion history up to redshifts 5-6. A brief review on both subjects is presented here.

  2. Identifying crucial parameter correlations maintaining bursting activity.

    Directory of Open Access Journals (Sweden)

    Anca Doloc-Mihu

    2014-06-01

    Full Text Available Recent experimental and computational studies suggest that linearly correlated sets of parameters (intrinsic and synaptic properties of neurons allow central pattern-generating networks to produce and maintain their rhythmic activity regardless of changing internal and external conditions. To determine the role of correlated conductances in the robust maintenance of functional bursting activity, we used our existing database of half-center oscillator (HCO model instances of the leech heartbeat CPG. From the database, we identified functional activity groups of burster (isolated neuron and half-center oscillator model instances and realistic subgroups of each that showed burst characteristics (principally period and spike frequency similar to the animal. To find linear correlations among the conductance parameters maintaining functional leech bursting activity, we applied Principal Component Analysis (PCA to each of these four groups. PCA identified a set of three maximal conductances (leak current, [Formula: see text]Leak; a persistent K current, [Formula: see text]K2; and of a persistent Na+ current, [Formula: see text]P that correlate linearly for the two groups of burster instances but not for the HCO groups. Visualizations of HCO instances in a reduced space suggested that there might be non-linear relationships between these parameters for these instances. Experimental studies have shown that period is a key attribute influenced by modulatory inputs and temperature variations in heart interneurons. Thus, we explored the sensitivity of period to changes in maximal conductances of [Formula: see text]Leak, [Formula: see text]K2, and [Formula: see text]P, and we found that for our realistic bursters the effect of these parameters on period could not be assessed because when varied individually bursting activity was not maintained.

  3. Are Gamma-Ray Bursts Standard Candles?

    OpenAIRE

    Li, Li-Xin

    2007-01-01

    By dividing a sample of 48 long-duration gamma-ray bursts (GRBs) into four groups with redshift from low to high and fitting each group with the Amati relation log Eiso = a + b log Epeak, I find that parameters a and b vary with the mean redshift of the GRBs in each group systematically and significantly. The results suggest that GRBs evolve strongly with the cosmic redshift and hence are not standard candles.

  4. The Euclidean distribution of Fast Radio Bursts

    OpenAIRE

    Oppermann, Niels; Connor, Liam; Pen, Ue-Li

    2016-01-01

    We investigate whether current data on the distribution of observed flux densities of Fast Radio Bursts (FRBs) are consistent with a constant source density in Euclidean space. We use the number of FRBs detected in two surveys with different characteristics along with the observed signal-to-noise ratios of the detected FRBs in a formalism similar to a V/V_max-test to constrain the distribution of flux densities. We find consistency between the data and a Euclidean distribution. Any extension ...

  5. Bursting of sensitive polymersomes induced by curling

    OpenAIRE

    Mabrouk, Elyes; Cuvelier, Damien; Brochard-Wyart, Françoise; Nassoy, Pierre; Li, Min-Hui

    2009-01-01

    Polymersomes, which are stable and robust vesicles made of block copolymer amphiphiles, are good candidates for drug carriers or micro/nanoreactors. Polymer chemistry enables almost unlimited molecular design of responsive polymersomes whose degradation upon environmental changes has been used for the slow release of active species. Here, we propose a strategy to remotely trigger instantaneous polymersome bursting. We have designed asymmetric polymer vesicles, in which only one leaflet is com...

  6. Gamma Ray Bursts and their Optical Counterparts

    International Nuclear Information System (INIS)

    Gamma Ray Bursts (GRB) have been discovered 38 years ago and still remain one of the most intriguing puzzles of astrophysics. In this paper we remind briefly the history of GRB studies and review the current experimental evidence with the emphasis on GRB optical counterparts. At the end we introduce '' π of the Sky '' project designed to catch prompt optical emission from GRB sources. (author)

  7. Gamma-ray bursts - a critical review

    International Nuclear Information System (INIS)

    We present a short general introduction into the field of gamma-ray bursts (GRBs) research, summarizing the past and the present status. We give an general view of the GRBs observations to date, both in the prompt emission phase as well as in the afterglow phase, and a brief primer into the theory, mainly in the frame-work of the fireball model. (authors)

  8. A Fast Radio Burst Host Galaxy

    CERN Document Server

    Keane, E F; Bhandari, S; Barr, E; Bhat, N D R; Burgay, M; Caleb, M; Flynn, C; Jameson, A; Kramer, M; Petroff, E; Possenti, A; van Straten, W; Bailes, M; Burke-Spolaor, S; Eatough, R P; Stappers, B W; Totani, T; Honma, M; Furusawa, H; Hattori, T; Morokuma, T; Niino, Y; Sugai, H; Terai, T; Tominaga, N; Yamasaki, S; Yasuda, N; Allen, R; Cooke, J; Jencson, J; Kasliwal, M M; Kaplan, D L; Tingay, S J; Williams, A; Wayth, R; Chandra, P; Perrodin, D; Berezina, M; Mickaliger, M; Bassa, C

    2016-01-01

    In recent years, millisecond duration radio signals originating from distant galaxies appear to have been discovered in the so-called Fast Radio Bursts. These signals are dispersed according to a precise physical law and this dispersion is a key observable quantity which, in tandem with a redshift measurement, can be used for fundamental physical investigations. While every fast radio burst has a dispersion measurement, none before now have had a redshift measurement, due to the difficulty in pinpointing their celestial coordinates. Here we present the discovery of a fast radio burst and the identification of a fading radio transient lasting $\\sim 6$ days after the event, which we use to identify the host galaxy; we measure the galaxy's redshift to be $z=0.492\\pm0.008$. The dispersion measure and redshift, in combination, provide a direct measurement of the cosmic density of ionised baryons in the intergalactic medium of $\\Omega_{\\mathrm{IGM}}=4.9 \\pm 1.3\\%$, in agreement with the expectation from WMAP, and i...

  9. The Swift Gamma-Ray Burst Mission

    CERN Document Server

    Gehrels, N; Burrows, D N; Chincarini, G L; Cominsky, L R; Giommi, P; Hurley, K C; Marshall, F E; Mason, K O; Mészáros, P; Nousek, J A; Roming, P W A; Wells, A A; White, N E; Team, Swift Science

    2004-01-01

    The Swift mission, scheduled for launch in early 2004, is a multiwavelength observatory for gamma-ray burst (GRB) astronomy. It is the first-of-its-kind autonomous rapid-slewing satellite for transient astronomy and pioneers the way for future rapid-reaction and multiwavelength missions. It will be far more powerful than any previous GRB mission, observing more than 100 bursts per year and performing detailed X-ray and UV/optical afterglow observations spanning timescales from 1 minute to several days after the burst. The objectives are to determine the origin of GRBs; classify GRBs and search for new types; study the interaction of the ultra-relativistic outflows of GRBs with their surrounding medium; and use GRBs to study the early universe out to z>10. The mission is being developed by a NASA-led international collaboration. It will carry three instruments: a new-generation wide-field gamma-ray (15-150 keV) detector; a narrow-field X-ray telescope; and a narrow-field UV/optical telescope. Redshift determin...

  10. Supercollapsars and their X-ray Bursts

    CERN Document Server

    Komissarov, S S

    2009-01-01

    The very first stars in the Universe can be very massive, frequently reaching $10^3M_\\odot$. If born in large numbers such massive stars can have strong impact on the subsequent star formation producing strong ionising radiation and contaminating the primordial gas with heavy elements. They would leave behind massive black holes that could act as seeds for growing supermassive black holes of active galactic nuclei. Given the anticipated fast rotation such stars would end their live as supermassive collapsars and drive powerful magnetically-dominated jets. In this letter we investigate the possibility of observing the bursts of high-energy emission similar to the Long Gamma Ray Bursts associated with normal collapsars. We show that during the collapse of supercollapsars, the Blandford-Znajek mechanism can extract up to $10^{56}$erg at a rate of few$\\times10^{52}$erg/s. Due to the higher intrinsic time scale and higher redshift the observed burst duration increases by a factor of $\\simeq 1000$ and can reach one...

  11. Composite-flywheel burst-containment study

    Energy Technology Data Exchange (ETDEWEB)

    Sapowith, A D; Handy, W E

    1982-04-08

    A key component impacting total flywheel energy storage system weight is the containment structure. This report addresses the factors that shape this structure and define its design criteria. In addition, containment weight estimates are made for the several composite flywheel designs of interest so that judgements can be made as to the relative weights of their containment structure. The requirements set down for this program were that all containment weight estimates be based on a 1 kWh burst. It should be noted that typical flywheel requirements for regenerative braking of small automobiles call for deliverable energies of 0.25 kWh. This leads to expected maximum burst energies of 0.5 kWh. The flywheels studied are those considered most likely to be carried further for operational design. These area: The pseudo isotropic disk flywheel, sometimes called the alpha ply; the SMC molded disk; either disk with a carbon ring; the subcircular rim with cruciform hub; and Avco's bi-directional circular weave disk. The flywheel materials for the disk are S-glass; the subcircular rim is Kevlar over S-glass. Test data on flywheel bursts and containment failures were analyzed. Recommendations are made for further testing.

  12. Dihydroxyoctadecamonoenoate esters inhibit the neutrophil respiratory burst

    Indian Academy of Sciences (India)

    David Alan Thompson; Bruce D Hammock

    2007-03-01

    The leukotoxins [9(10)- and 12(13)-EpOME] are produced by activated inflammatory leukocytes such as neutrophils. High EpOME levels are observed in disorders such as acute respiratory distress syndrome and in patients with extensive burns. Although the physiological significance of the EpOMEs remains poorly understood, in some systems, the EpOMEs act as a protoxin, with their corresponding epoxide hydrolase metabolites, 9,10- and 12,13-DiHOME, specifically exerting toxicity. Both the EpOMEs and the DiHOMEs were also recently shown to have neutrophil chemotactic activity. We evaluated whether the neutrophil respiratory burst, a surge of oxidant production thought to play an important role in limiting certain bacterial and fungal infections, is modulated by members of the EpOME metabolic pathway. We present evidence that the DiHOMEs suppress the neutrophil respiratory burst by a mechanism distinct from that of respiratory burst inhibitors such as cyclosporin H or lipoxin A4, which inhibit multiple aspects of neutrophil activation.

  13. Radio flares from gamma-ray bursts

    CERN Document Server

    Kopac, D; Kobayashi, S; Virgili, F J; Harrison, R; Japelj, J; Guidorzi, C; Melandri, A; Gomboc, A

    2015-01-01

    We present predictions of centimeter and millimeter radio emission from reverse shocks in the early afterglows of gamma-ray bursts with the goal of determining their detectability with current and future radio facilities. Using a range of GRB properties, such as peak optical brightness and time, isotropic equivalent gamma-ray energy and redshift, we simulate radio light curves in a framework generalized for any circumburst medium structure and including a parametrization of the shell thickness regime that is more realistic than the simple assumption of thick- or thin-shell approximations. Building on earlier work by Mundell et al. (2007) and Melandri et al. (2010) in which the typical frequency of the reverse shock was suggested to lie at radio, rather than optical wavelengths at early times, we show that the brightest and most distinct reverse-shock radio signatures are detectable up to 0.1 -- 1 day after the burst, emphasizing the need for rapid radio follow-up. Detection is easier for bursts with later opt...

  14. Automatic Cloud Bursting under FermiCloud

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Hao [Fermilab; Shangping, Ren [IIT; Garzoglio, Gabriele [Fermilab; Timm, Steven [Fermilab; Bernabeu, Gerard [Fermilab; Kim, Hyun Woo; Chadwick, Keith; Jang, Haengjin [KISTI, Daejeon; Noh, Seo-Young [KISTI, Daejeon

    1900-01-01

    Cloud computing is changing the infrastructure upon which scientific computing depends from supercomputers and distributed computing clusters to a more elastic cloud-based structure. The service-oriented focus and elasticity of clouds can not only facilitate technology needs of emerging business but also shorten response time and reduce operational costs of traditional scientific applications. Fermi National Accelerator Laboratory (Fermilab) is currently in the process of building its own private cloud, FermiCloud, which allows the existing grid infrastructure to use dynamically provisioned resources on FermiCloud to accommodate increased but dynamic computation demand from scientists in the domains of High Energy Physics (HEP) and other research areas. Cloud infrastructure also allows to increase a private cloud’s resource capacity through “bursting” by borrowing or renting resources from other community or commercial clouds when needed. This paper introduces a joint project on building a cloud federation to support HEP applications between Fermi National Accelerator Laboratory and Korea Institution of Science and Technology Information, with technical contributions from the Illinois Institute of Technology. In particular, this paper presents two recent accomplishments of the joint project: (a) cloud bursting automation and (b) load balancer. Automatic cloud bursting allows computer resources to be dynamically reconfigured to meet users’ demands. The load balance algorithm which the cloud bursting depends on decides when and where new resources need to be allocated. Our preliminary prototyping and experiments have shown promising success, yet, they also have opened new challenges to be studied

  15. A Hydrodynamic Model for Slug Frequency in Horizontal Gas-Liquid Two-Phase Flow%水平管气液两相弹状流液弹频率的水动力学新模型

    Institute of Scientific and Technical Information of China (English)

    刘磊; 孙贺东; 胡志华; 周芳德

    2003-01-01

    The prediction of slug frequency has important significance on gas-liquid two-phase flow. A hydrodynamic model was put forward to evaluate slug frequency for horizontal two-phase flow, based on the dependence of slug frequency on the frequency of unstable interfacial wave. Using air and water, experimental verification of the model was carried out in a large range of flow parameters. Six electrical probes were installed at different positions of a horizontal plexiglass pipe to detect slug frequency development. The pipe is 30 m long and its inner diameter is 24 mm. It is observed experimentally that the interfacial wave frequency at the inlet is about 1 to 3 times the frequency of stable slug. The slug frequencies predicted by the model fit well with Tronconi (1990) model and the experimental data. The combination of the hydrodynamic model and the experimental data results in a conclusion that the frequency of equilibrium liquid slug is approximately half the minimum frequency of interfacial wave.

  16. Experimental Investigation of Slug Development on Horizontal Two-phase Flow%水平管内气液段塞流液塞发展特性实验研究

    Institute of Scientific and Technical Information of China (English)

    顾汉洋; 郭烈锦

    2008-01-01

    Slug initiation and subsequent evolution along a 5.0 cm ID, 16m long horizontal pipe are experimen-tally studied. The transient characteristics of interfacial structures are described by using simultaneous measure-ments of the liquid height at multiple locations along the pipe. Various effects of superficial gas and liquid velocities and pressure oscillation on the slug initiation and evolution along the pipe are illustrated. It is found that the slug is initiated by a deterministic process with replenishment and depletion of liquid near the inlet for the superficial gas velocity USG3.0 m·s-1 and by a stochastic process with wave coalescence along the pipe for USG>3.0 m·s-1. The evolution of the slugs is strongly affected by superficial gas and liquid velocities for USG<3.0 m·s-1 but weakly af-fected by the superficial gas velocity for USG>3.0 m·s-1. The suppression of pressure oscillation at the pipe inlet significantly delays the onset of slugging, with slugs forming postponed further downstream. The slug frequency at the outlet is, however, not affected by the variation in the pressure oscillation.

  17. Numerical study on the effect of initial flow velocity on liquid film thickness of accelerated slug flow in a micro tube

    International Nuclear Information System (INIS)

    Highlights: • We examine liquid film thickness of accelerated slug flows with initial velocity. • Liquid film of accelerated flow is thinner than that of steady flow. • Liquid film is thinner for smaller initial flow velocity and larger acceleration. • Velocity profile in the liquid slug is approximated by that of single phase flow. • New correlation for liquid film thickness of accelerated slug flow is developed. - Abstract: Numerical simulation of air–water slug flows accelerated from steady states with different initial velocities in a micro tube is conducted. It is shown that the liquid film formed between the gas bubble and the wall in an accelerated flow is significantly thinner than that in a steady flow at the same instantaneous capillary number. Specifically, the liquid film thickness is kept almost unchanged just after the onset of acceleration, and then gradually increases and eventually converges to that of an accelerated flow from zero initial velocity. Due to the flow acceleration, the Stokes layer is generated from the wall, and the instant velocity profile can be given by superposition of the Stokes layer and the initial parabolic velocity profile of a steady flow. It is found that the velocity profile inside a liquid slug away from the bubble can be well predicted by the analytical solution of a single-phase flow with acceleration. The change of the velocity profile in an accelerated flow changes the balance between the inertia, surface tension and viscous forces around the meniscus region, and thus the resultant liquid film thickness. By introducing the displacement thickness, the existing correlation for liquid film thickness in a steady flow (Han and Shikazono, 2009) is extended so that it can be applied to a flow with acceleration from an arbitrary initial velocity. It is demonstrated that the proposed correlation can predict liquid film thickness at Re < 4600 within the range of ±10% accuracy

  18. Dynamic encoding of natural luminance sequences by LGN bursts.

    Directory of Open Access Journals (Sweden)

    Nicholas A Lesica

    2006-07-01

    Full Text Available In the lateral geniculate nucleus (LGN of the thalamus, visual stimulation produces two distinct types of responses known as tonic and burst. Due to the dynamics of the T-type Ca(2+ channels involved in burst generation, the type of response evoked by a particular stimulus depends on the resting membrane potential, which is controlled by a network of modulatory connections from other brain areas. In this study, we use simulated responses to natural scene movies to describe how modulatory and stimulus-driven changes in LGN membrane potential interact to determine the luminance sequences that trigger burst responses. We find that at low resting potentials, when the T channels are de-inactivated and bursts are relatively frequent, an excitatory stimulus transient alone is sufficient to evoke a burst. However, to evoke a burst at high resting potentials, when the T channels are inactivated and bursts are relatively rare, prolonged inhibitory stimulation followed by an excitatory transient is required. We also observe evidence of these effects in vivo, where analysis of experimental recordings demonstrates that the luminance sequences that trigger bursts can vary dramatically with the overall burst percentage of the response. To characterize the functional consequences of the effects of resting potential on burst generation, we simulate LGN responses to different luminance sequences at a range of resting potentials with and without a mechanism for generating bursts. Using analysis based on signal detection theory, we show that bursts enhance detection of specific luminance sequences, ranging from the onset of excitatory sequences at low resting potentials to the offset of inhibitory sequences at high resting potentials. These results suggest a dynamic role for burst responses during visual processing that may change according to behavioral state.

  19. Crawling through time: Transition of snails to slugs dating back to the Paleozoic, based on mitochondrial phylogenomics.

    Science.gov (United States)

    Medina, Mónica; Lal, Shruti; Vallès, Yvonne; Takaoka, Tori L; Dayrat, Benoît A; Boore, Jeffrey L; Gosliner, Terrence

    2011-03-01

    Sea slugs (Gastropoda: Opisthobranchia) are characterized by extensive morphological homoplasy. In particular, reduced or absent shells are predominant throughout the group. This trend towards shell loss has resulted in a poor fossil record. DNA-based phylogenies have been helpful in improving our understanding of the evolution of this group and major clades are emerging. We report 13 new complete opisthobranch mitochondrial genomes that provide robust support for some of these emerging nodes. We name three new clades within the Opisthobranchia, the Actopleura (Acteonoidea plus Nudipleura), Placoesophaga (Cephalaspidea plus Anaspidea), and Siphoglossa (Sacoglossa plus the Siphonaria). Finally we use molecular clock dating that suggests an earlier opisthobranch divergence than previously reported. The implications of this evolutionary scenario are discussed. PMID:21429465

  20. FERMI DETECTION OF DELAYED GeV EMISSION FROM THE SHORT GAMMA-RAY BURST 081024B

    International Nuclear Information System (INIS)

    We report on the detailed analysis of the high-energy extended emission from the short gamma-ray burst (GRB) 081024B detected by the Fermi Gamma-ray Space Telescope. Historically, this represents the first clear detection of temporal extended emission from a short GRB. The light curve observed by the Fermi Gamma-ray Burst Monitor lasts approximately 0.8 s whereas the emission in the Fermi Large Area Telescope lasts for about 3 s. Evidence of longer lasting high-energy emission associated with long bursts has been already reported by previous experiments. Our observations, together with the earlier reported study of the bright short GRB 090510, indicate similarities in the high-energy emission of short and long GRBs and open the path to new interpretations.

  1. Mating behaviour in the sea slug Elysia timida (Opisthobranchia, Sacoglossa: hypodermic injection, sperm transfer and balanced reciprocity

    Directory of Open Access Journals (Sweden)

    Anthes Nils

    2007-07-01

    Full Text Available Abstract Background In simultaneous hermaphrodites with copulation and internal fertilization it is often unclear whether reciprocal sperm exchange results from the unconditional willingness of both partners to donate and receive sperm, or whether it follows from a more controlled process such as conditional reciprocal sperm exchange, i.e. sperm trading. While in some sea slugs mating is assumed to be based on sperm trading, it seems to be unconditional in others. Here, we describe the unusual mating behaviour of Elysia timida, a small sacoglossan, focussing on indications for conditional reciprocity. Results E. timida shows an as yet unique combination of a long series of hypodermic transfers followed by a short phase with standard insemination into a female genital aperture. Hypodermic transfer takes place in the form of repeated small injections into the dorsal surface of the partner, interrupted by synchronised circling movements. In the final mating phase sperm is transferred into the female genital aperture in a short period. In both phases the two mating individuals show a high degree of transfer symmetry and synchrony. While total duration and number of transfers were balanced within pairs, they varied significantly between pairs. Furthermore, looking at individual hypodermic transfers within pairs, reciprocal transfers lasted longer than unilateral transfers. Final sperm transfers were always reciprocal except for two cases which also diverted from the usual pattern in ways that were suggestive of a conflict over reciprocity. Conclusion Our results suggest that individual mating decisions in E. timida depend on what the partner does, indicating conditional reciprocity. If hypodermic transfers also involve the transfer of sperm (which remains to be confirmed, this system represents an up to now unique transition stage between hypodermic and standard insemination, both of which are widespread in this group of sea slugs, but never have

  2. SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype

    Directory of Open Access Journals (Sweden)

    Bhat-Nakshatri Poornima

    2010-08-01

    Full Text Available Abstract Background Breast cancer cells with CD44+/CD24- cell surface marker expression profile are proposed as cancer stem cells (CSCs. Normal breast epithelial cells that are CD44+/CD24- express higher levels of stem/progenitor cell associated genes. We, amongst others, have shown that cancer cells that have undergone epithelial to mesenchymal transition (EMT display the CD44+/CD24- phenotype. However, whether all genes that induce EMT confer the CD44+/CD24- phenotype is unknown. We hypothesized that only a subset of genes associated with EMT generates CD44+/CD24- cells. Methods MCF-10A breast epithelial cells, a subpopulation of which spontaneously acquire the CD44+/CD24- phenotype, were used to identify genes that are differentially expressed in CD44+/CD24- and CD44-/CD24+ cells. Ingenuity pathway analysis was performed to identify signaling networks that linked differentially expressed genes. Two EMT-associated genes elevated in CD44+/CD24- cells, SLUG and Gli-2, were overexpressed in the CD44-/CD24+ subpopulation of MCF-10A cells and MCF-7 cells, which are CD44-/CD24+. Flow cytometry and mammosphere assays were used to assess cell surface markers and stem cell-like properties, respectively. Results Two thousand thirty five genes were differentially expressed (p Conclusions EMT-mediated generation of CD44+/CD24- or CD44+/CD24+ cells depends on the genes that induce or are associated with EMT. Our studies reveal a role for TNF in altering the phenotype of breast CSC. Additionally, the CD44+/CD24+ phenotype, in the context of SLUG overexpression, can be associated with breast CSC "stemness" behavior based on mammosphere forming ability.

  3. Observations of Gamma-ray Bursts with the Fermi Large Area Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Longo, Francesco, E-mail: francesco.longo@ts.infn.it [Dipartimento di Fisica, Università di Trieste and INFN, sezione di Trieste, via Valerio 2, I-34127 Trieste (Italy); Vianello, Giacomo; Omodei, Nicola [Stanford University (HEPL), 452 Lomita Mall, Stanford, CA 94205 (United States); Piron, Frederic; Vasilieou, Vlasios [Laboratoire Univers et Particules de Montpellier, Universite de Montpellier II, CNRS/IN2P3, CC72, Place E. Bataillon, F-34095 Montpellier Cedex 5 (France); Razzaque, Soebur [Department of Physics, University of Johannesburg, P.O. Box 524, Auckland Park 2006 (South Africa)

    2014-04-01

    The Fermi observatory, with its Gamma-ray Bursts Monitor (GBM) and Large Area Telescope (LAT), is observing Gamma-ray Bursts (GRBs) with a very large spectral coverage and unprecedented sensitivity, from ∼10keV to >300GeV. In the first 3 years of the mission it observed emission above 100 MeV from 35 GRBs. In this paper we review the main results obtained on such a sample, highlighting also the relationships with the low-energy spectral and temporal features (as measured by the GBM). Some recent results on high energy photons from GRBs obtained with the preliminary Pass 8 new event-level reconstruction will be discussed.

  4. THE FERMI GBM GAMMA-RAY BURST SPECTRAL CATALOG: THE FIRST TWO YEARS

    Energy Technology Data Exchange (ETDEWEB)

    Goldstein, Adam; Burgess, J. Michael; Preece, Robert D.; Briggs, Michael S.; Guiriec, Sylvain; Connaughton, Valerie; Paciesas, William S.; Bhat, P. N.; Chaplin, Vandiver [Physics Department, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Van der Horst, Alexander J.; Meegan, Charles A. [Universities Space Research Association, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Wilson-Hodge, Colleen A.; Fishman, Gerald J. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Von Kienlin, Andreas; Bissaldi, Elisabetta; Diehl, Roland; Foley, Suzanne [Max-Planck-Institut fuer extraterrestrische Physik, Giessenbachstrasse 1, 85748 Garching (Germany); Fitzpatrick, Gerard [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Gibby, Melissa; Giles, Misty [Jacobs Technology, 1500 Perimeter Parkway, Huntsville, AL 35806 (United States); and others

    2012-03-01

    We present systematic spectral analyses of gamma-ray bursts (GRBs) detected by the Fermi Gamma-Ray Burst Monitor (GBM) during its first two years of operation. This catalog contains two types of spectra extracted from 487 GRBs, and by fitting four different spectral models, this results in a compendium of over 3800 spectra. The models were selected based on their empirical importance to the spectral shape of many GRBs, and the analysis performed was devised to be as thorough and objective as possible. We describe in detail our procedure and criteria for the analyses, and present the bulk results in the form of parameter distributions. This catalog should be considered an official product from the Fermi GBM Science Team, and the data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center.

  5. Jamming effects on code synchronization of burst-mode frequency-hop spread-spectrum

    Science.gov (United States)

    van Grouw, Mike G.; Wicker, Mark A.

    The authors characterize the performance of a multiple-dwell FHSS (frequency-hopping spread-spectrum) code synchronization scheme in the presence of channel dynamics. Random hop jamming is assumed. The coarse acquisition system uses both passive and active correlation to implement a serial search of the code-uncertainty region. The in-lock monitoring is accomplished using a two-dwell active correlator with a relatively long integration time. Both burst- and continuous-mode communications links are considered. Appropriate performance parameters are developed, and design considerations are discussed. Performance curves are given for the various cases considered. Although a fixed-threshold multiple-dwell synchronization scheme adequately mitigates the effects of dynamic jamming in a continuous-mode communications link, it is shown to be inadequate for a burst-mode communications link.

  6. Implications for Understanding Short Gamma-Ray Bursts Detected by {\\it Swift}

    CERN Document Server

    Shao, Lang; Fan, Yi-Zhong; Zhang, Fu-Wen; Jin, Zhi-Ping; Wei, Da-Ming

    2011-01-01

    In an effort to understand the puzzle of classifying Gamma-Ray Bursts (GRBs), we have a systematic study of {\\it Swift} GRBs and investigate several issues on short GRBs. Though short GRBs have a short ($\\lesssim2$ s) prompt duration as monitored by {\\it Swift} Burst Alert Telescope (BAT), the composite light curves including both the prompt and afterglow emission suggest that most of them have a similar radiative feature as the long GRBs. Besides, some well-studied short GRBs might also have an intrinsically long prompt duration, which renders them a type of short GRB imposters. Genuine short GRBs might be rare so that to discriminate the observed short GRBs is, not surprisingly, troublesome. In particular, the observational biases in the host identification and redshift measurement of GRBs should be taken with great caution. The redshift distribution which has been proposed to be different for long and short GRBs might have been strongly affected by the measurement methods.

  7. Strain bursts in plastically deforming Molybdenum micro- and nanopillars

    OpenAIRE

    Zaiser, Michael; Schwerdtfeger, Jan; Schneider, Andreas; Frick, Carl; Clark, Blythe Gore; Gruber, Patric; Arzt, Eduard

    2009-01-01

    Abstract Plastic deformation of micron and sub-micron scale specimens is characterized by intermittent sequences of large strain bursts (dislocation avalanches) which are separated by regions of near-elastic loading. In the present investigation we perform a statistical characterization of strain bursts observed in stress-controlled compressive deformation of monocrystalline molybdenum micropillars. We characterize the bursts in terms of the associated elongation increments and pea...

  8. Full System Bifurcation Analysis of Endocrine Bursting Models

    OpenAIRE

    Rieß, Thorsten; Sherman, Arthur; Tsaneva-Atanasova, KT; Osinga, HM

    2010-01-01

    Plateau bursting is typical of many electrically excitable cells, such as endocrine cells that secrete hormones and some types of neurons that secrete neurotransmitters. Although in many of these cell types the bursting patterns are regulated by the interplay between voltage-gated calcium channels and calcium-sensitive potassium channels, they can be very different. For example, in insulin-secreting pancreatic β-cells, plateau bursting is characterized by well-defined spikes during the depola...

  9. A Limited Deflection Routing Algorithm Based on Burst Loss Threshold in OBS Networks

    Institute of Scientific and Technical Information of China (English)

    WANG Ru-yan; LONG Ke-ping; WU Wei; YANG Xiao-long; ZHU Wei-le

    2005-01-01

    The deflection routing protocol is an effective contention resolution in Optical Burst Switching network. However, it can worsen loss performance of non-deflected burst on the deflection route. To improve the burst loss performance, a limited deflection routing scheme based on burst loss threshold is proposed to prevent injudicious deflection routing. By using threshold check function, it restrainedly allows the deflected burst to preemptive network resource, consequently, improve the QoS performance of non-deflected burst. Simulation results show that the scheme can efficiently prevent deflected burst contending with non-deflected burst on deflection route, and effectively improve the burst loss performance of entire networks.

  10. ESTIMATION OF THE BURST LENGTH IN OBS NETWORKS

    OpenAIRE

    Pallavi S.; M. Lakshmi

    2014-01-01

    This paper presents an overview of the optical burst switching (OBS) and discusses the major components. In OBS, the length of the burst arriving at a particular node is unknown, and hence, node design is very complex. In OBS first control, packet is transmitted and reserve the path as in circuit switching, thereafter, the data bursts is transmitted. In this paper, a poisson arrival of packets is considered and estimation is made on the size of the burst length. The results presented in the p...

  11. The long and the short of gamma-ray bursts

    CERN Document Server

    Katz, J I

    1995-01-01

    We report evidence from the 3B Catalogue that long (T_{90} > 10 s) and short (T_{90} 1 MeV. This implies different spatial origin and physical processes for long and short bursts. Long bursts may be explained by accretion-induced collapse. Short bursts require another mechanism, for which we suggest neutron star collisions. These are capable of producing neutrino bursts as short as a few ms, consistent with the shortest observed time scales in GRB. We briefly investigate the parameters of clusters in which neutron star collisons may occur, and discuss the nuclear evolution of expelled and accelerated matter.

  12. The First Swift BAT Gamma-Ray Burst Catalog

    OpenAIRE

    Sakamoto, T.; Barthelmy, S. D.; Barbier, L.; Cummings, J. R.; Fenimore, E. E.; Gehrels, N.; Hullinger, D.; Krimm, H. A.; Markwardt, C. B.; Palmer, D. M.; Parsons, A. M.; Sato, G.; Stamatikos, M.; Tueller, J.; Ukwatta, T. N.

    2007-01-01

    We present the first Swift Burst Alert Telescope (BAT) catalog of gamma-ray bursts (GRBs), which contains bursts detected by the BAT between 2004 December 19 and 2007 June 16. This catalog (hereafter BAT1 catalog) contains burst trigger time, location, 90% error radius, duration, fluence, peak flux, and time averaged spectral parameters for each of 237 GRBs, as measured by the BAT. The BAT-determined position reported here is within 1.75' of the Swift X-ray Telescope (XRT)-determined position...

  13. Study on cosmic gamma bursts in the ''KONUS'' experiment

    International Nuclear Information System (INIS)

    Made are the investigations of cosmic gamma bursts with the help of the ''Konus'' apparatus, positioned on the ''Venera 11'' and ''Venera 12'' automatic interplanetary stations. 37 gamma bursts have been recorded in the energy range from 50 to 150 keV during the observation period from September to December 1978. Time profiles of bursts on 4, 9 and 24.11.1978 are presented. For the most events the time of burst increase and decrease constitute parts and units of seconds. Differential energy spectra are measured for all recorded bursts. In many cases the spectrum shape is similar to the grade one with the 1.5-2.3 index. In a graphical form built up are the integral distributions of gamma bursts appearence frequency in dependence on their intensity and maximum capacity in the burst peak. Galaxy coordinates of the 17-teen bursts, for which a simple localization is possible, are put on the celestial sphere map. The type of the integral distributions and the source distribution about the celestial sphere show that the gamma burst sources are whithin the Galaxy

  14. Observations of the structure of Type IIIb radio bursts

    International Nuclear Information System (INIS)

    The authors have observed short duration, narrow band Type IIIb radio bursts that occur just before the onset of a normal Type III burst. These observations were made with a multichannel radiometer with a center frequency of 25 MHz, time constant of 10 milliseconds and frequency resolution of 100 KHz. The average half power duration of a typical element of a Type III burst was determined. It was found to be very similar to the time profile of a normal Type III burst, i.e., sharp rise and exponential type decay. (Auth.)

  15. Percussion drilling of metals using bursts of nanosecond pulses.

    Science.gov (United States)

    Hendow, Sami T; Romero, Rosa; Shakir, Sami A; Guerreiro, Paulo T

    2011-05-23

    The effect of ns bursting on percussion drilling of metal is investigated experimentally and analytically, and compared with the efficiency and quality of drilling using single ns pulses. Key advantages are demonstrated, correlating well with the results from a thermal theoretical model. The 1064 nm bursts contain up to 14 pulses of various pulse widths and spacing, and at frequencies of tens of MHz within the burst. The individual pulses have pulse widths of 10 to 200 ns, and up to 12 kW peak power. Burst repetition frequency is single shot to 500 kHz. PMID:21643280

  16. A behavioral role for feature detection by sensory bursts.

    Science.gov (United States)

    Marsat, Gary; Pollack, Gerald S

    2006-10-11

    Brief episodes of high-frequency firing of sensory neurons, or bursts, occur in many systems, including mammalian auditory and visual systems, and are believed to signal the occurrence of particularly important stimulus features, i.e., to function as feature detectors. However, the behavioral relevance of sensory bursts has not been established in any system. Here, we show that bursts in an identified auditory interneuron of crickets reliably signal salient stimulus features and reliably predict behavioral responses. Our results thus demonstrate the close link between sensory bursts and behavior.

  17. Coupled hydro-neutronic calculations for fast burst reactor accidents

    International Nuclear Information System (INIS)

    Methods are described for determining the fully coupled neutronic/hydrodynamic response of fast burst reactors (FBR) under disruptive accident conditions. Two code systems, PAD (1 -D Lagrangian) and NIKE-PAGOSA (3-D Eulerian) were used to accomplish this. This is in contrast to the typical methodology that computes these responses by either single point kinetics or in a decoupled manner. This methodology is enabled by the use of modem supercomputers (CM-200). Two examples of this capability are presented: an unreflected metal fast burst assembly, and a reflected fast burst assembly typical of the Skua or SPR-III class of fast burst reactor

  18. Emergent synchronous bursting of oxytocin neuronal network.

    Directory of Open Access Journals (Sweden)

    Enrico Rossoni

    Full Text Available When young suckle, they are rewarded intermittently with a let-down of milk that results from reflex secretion of the hormone oxytocin; without oxytocin, newly born young will die unless they are fostered. Oxytocin is made by magnocellular hypothalamic neurons, and is secreted from their nerve endings in the pituitary in response to action potentials (spikes that are generated in the cell bodies and which are propagated down their axons to the nerve endings. Normally, oxytocin cells discharge asynchronously at 1-3 spikes/s, but during suckling, every 5 min or so, each discharges a brief, intense burst of spikes that release a pulse of oxytocin into the circulation. This reflex was the first, and is perhaps the best, example of a physiological role for peptide-mediated communication within the brain: it is coordinated by the release of oxytocin from the dendrites of oxytocin cells; it can be facilitated by injection of tiny amounts of oxytocin into the hypothalamus, and it can be blocked by injection of tiny amounts of oxytocin antagonist. Here we show how synchronized bursting can arise in a neuronal network model that incorporates basic observations of the physiology of oxytocin cells. In our model, bursting is an emergent behaviour of a complex system, involving both positive and negative feedbacks, between many sparsely connected cells. The oxytocin cells are regulated by independent afferent inputs, but they interact by local release of oxytocin and endocannabinoids. Oxytocin released from the dendrites of these cells has a positive-feedback effect, while endocannabinoids have an inhibitory effect by suppressing the afferent input to the cells.

  19. Analysis of the PSD and PDF characteristics of gas-liquid slug flow%气液两相段塞流的PSD和PDF特征分析

    Institute of Scientific and Technical Information of China (English)

    肖荣鸽; 魏炳乾; 沙海涛; 姚培芬; 易冬蕊

    2012-01-01

    在气液两相段塞流理论基础上,通过大量实验,利用LabVIEW平台进行数据采集和处理,并引进数字信号理论和统计学分析方法,得出了段塞流在不同时期、不同形态的概率密度函数(PDF)特征和功率谱密度函数(PSD)特征.段塞流的压力概率密度函数呈现单峰、双峰、多峰分布,尤以双峰分布最为普遍;段塞流的压差概率密度函数分布符合正态分布,呈现单峰分布;段塞流的功率谱在整个频率范围内随着频率增大而缓慢下降,频率范围内出现两个幅度比较明显的特征峰.利用PSD和PDF特征分析可以进行气液两相流的流型识别,为研究流型和管道系统设计提供帮助.%In the gas-liquid pipeline transmission, slug flow is the most common flow regime, which brings a lot of trouble to normal running of the pipeline.The probability density function (PDF) and the power spectral density function (PSD) characteristics of the pressure and the pressure difference of the slug flow under different conditions are obtained by a lot of experiments and the statistical a-nalysis of experimental results. The experimental results are collected and processed using LabVIEW platform. It is shown that,the pres-sure PDF of the slug flow may present single-peak,double-peak or multi-peak distribution and the double-peak distribution is the most common; the pressure difference PDF of slug flow accords with normal distribution, that is, it presents single-peak distribution; The PSD of slug flow gradually reduces with the increase of frequency, and two obvious characteristic peaks appear in the frequency range. The PSD and PDF characteristics of gas-liquid slug flow can be used for the identification of the flow patterns of gas-liquid two-phase flow, which can guide effectively the design and running of the multiphase pipeline system.

  20. Fast Radio Bursts - I: Initial Cogitation

    CERN Document Server

    Keane, E F

    2014-01-01

    Fast radio bursts (FRBs) are millisecond-duration radio signals thought to originate from cosmological distances. Many authors are endeavouring to explain their progenitors, with others outlining their potential uses as cosmological probes. Here we describe some sub-optimal performance in existing FRB search software, which can reduce the volume probed by over 20%, and result in missed discoveries and incorrect flux densities and sky rates. Recalculating some FRB flux densities, we find that FRB 010125 was approximately 50% brighter than previously reported. Furthermore we consider incompleteness factors important to the population statistics. Finally we make data for the archival FRBs easily available, along with software to analyse these.