Sample records for burn direct injection

  1. The lean burn direct injection jet ignition gas engine

    Energy Technology Data Exchange (ETDEWEB)

    Boretti, Alberto A.; Watson, Harry C. [School of Science and Engineering, University of Ballarat, PO Box 663, Ballarat, Victoria 3353 (Australia)


    This paper presents a new in-cylinder mixture preparation and ignition system for various fuels including hydrogen, methane and propane. The system comprises a centrally located direct injection (DI) injector and a jet ignition (JI) device for combustion of the main chamber (MC) mixture. The fuel is injected in the MC with a new generation, fast actuating, high pressure, high flow rate DI injector capable of injection shaping and multiple events. This injector produces a bulk, lean stratified mixture. The JI system uses a second DI injector to inject a small amount of fuel in a small pre-chamber (PC). In the spark ignition (SI) version, a spark plug then ignites a slightly rich mixture. In the auto ignition version, a DI injector injects a small amount of higher pressure fuel in the small PC having a hot glow plug (GP) surface, and the fuel auto ignites in the hot air or when in contact with the hot surface. Either way the MC mixture is then bulk ignited through multiple jets of hot reacting gases. Bulk ignition of the lean, jet controlled, stratified MC mixture resulting from coupling DI with JI makes it possible to burn MC mixtures with fuel to air equivalence ratios reducing almost to zero for a throttle-less control of load diesel-like and high efficiencies over almost the full range of loads. (author)

  2. Detailed Characterization of Particulate Matter Emitted by Lean-Burn Gasoline Direct Injection Engine

    Energy Technology Data Exchange (ETDEWEB)

    Zelenyuk, Alla; Wilson, Jacqueline M.; Imre, Dan G.; Stewart, Mark L.; Muntean, George G.; Storey, John; Prikhodko, Vitaly; Lewis, Samuel T.; Eibl, Mary; Parks, James E.


    This study presents detailed characterization of the chemical and physical properties of PM emitted by a 2.0L BMW lean-burn turbocharged GDI engine operated under a number of combustion strategies that include lean homogeneous, lean stratified, stoichiometric, and fuel rich conditions. We characterized PM number concentrations, size distributions, and the size, mass, compositions, and effective density of fractal and compact individual exhaust particles. For the fractal particles, these measurements yielded fractal dimension, average diameter of primary spherules, and number of spherules, void fraction, and dynamic shape factors as function of particle size. Overall, the PM properties were shown to vary significantly with engine operation condition. Lean stratified operation yielded the most diesel-like size distribution and the largest PM number and mass concentrations, with nearly all particles being fractal agglomerates composed of elemental carbon with small amounts of ash and organics. In contrast, stoichiometric operation yielded a larger fraction of ash particles, especially at low speed and low load. Three distinct forms of ash particles were observed, with their fractions strongly dependent on engine operating conditions: sub-50 nm ash particles, abundant at low speed and low load, ash-containing fractal particles, and large compact ash particles that significantly contribute to PM mass loadings

  3. Multi-Element Lean Direct Injection Combustor Module Project (United States)

    National Aeronautics and Space Administration — We propose to develop a Multi-Element Lean Direct Injection, ME-LDI, Combustion concept with the following innovative features: 1. Independent, mini burning zones...

  4. Radial lean direct injection burner (United States)

    Khan, Abdul Rafey; Kraemer, Gilbert Otto; Stevenson, Christian Xavier


    A burner for use in a gas turbine engine includes a burner tube having an inlet end and an outlet end; a plurality of air passages extending axially in the burner tube configured to convey air flows from the inlet end to the outlet end; a plurality of fuel passages extending axially along the burner tube and spaced around the plurality of air passage configured to convey fuel from the inlet end to the outlet end; and a radial air swirler provided at the outlet end configured to direct the air flows radially toward the outlet end and impart swirl to the air flows. The radial air swirler includes a plurality of vanes to direct and swirl the air flows and an end plate. The end plate includes a plurality of fuel injection holes to inject the fuel radially into the swirling air flows. A method of mixing air and fuel in a burner of a gas turbine is also provided. The burner includes a burner tube including an inlet end, an outlet end, a plurality of axial air passages, and a plurality of axial fuel passages. The method includes introducing an air flow into the air passages at the inlet end; introducing a fuel into fuel passages; swirling the air flow at the outlet end; and radially injecting the fuel into the swirling air flow.

  5. UV-visible digital imaging of split injection in a Gasoline Direct Injection engine

    Directory of Open Access Journals (Sweden)

    Merola Simona Silvia


    Full Text Available Ever tighter limits on pollutant emissions and the need to improve energy conversion efficiency have made the application of gasoline direct injection (GDI feasible for a much wider scale of spark ignition engines. Changing the way fuel is delivered to the engine has thus provided increased flexibility but also challenges, such as higher particulate emissions. Therefore, alternative injection control strategies need to be investigated in order to obtain optimum performance and reduced environmental impact. In this study, experiments were carried out on a single-cylinder GDI optical engine fuelled with commercial gasoline in lean-burn conditions. The single-cylinder was equipped with the head of a commercial turbocharged engine with similar geometrical specifications (bore, stroke, compression ratio and wall guided fuel injection. Optical accessibility was ensured through a conventional elongated hollow Bowditch piston and an optical crown, accommodating a fused-silica window. Experimental tests were performed at fixed engine speed and injection pressure, whereas the injection timing and the number of injections were adjusted to investigate their influence on combustion and emissions. UV-visible digital imaging was applied in order to follow the combustion process, from ignition to the late combustion phase. All the optical data were correlated with thermodynamic analysis and measurements of exhaust emissions. Split injection strategies (i.e. two injections per cycle with respect to single injection increased combustion efficiency and stability thanks to an improvement of fuel air mixing. As a consequence, significant reduction in soot formation and exhaust emission with acceptable penalty in terms of HC and NOx were measured.

  6. Effect of water injection on nitric oxide emissions of a gas turbine combustor burning natural gas fuel (United States)

    Marchionna, N. R.; Diehl, L. A.; Trout, A. M.


    The effect of direct water injection on the exhaust gas emissions of a turbojet combustor burning natural gas fuel was investigated. The results are compared with the results from similar tests using ASTM Jet-A fuel. Increasing water injection decreased the emissions of oxides of nitrogen (NOX) and increased the emissions of carbon monoxide and unburned hydrocarbons. The greatest percentage decrease in NOX with increasing water injection was at the lowest inlet-air temperature tested. The effect of increasing inlet-air temperature was to decrease the effect of the water injection. The reduction in NOX due to water injection was almost identical to the results obtained with Jet-A fuel. However, the emission indices of unburned hydrocarbons, carbon monoxide, and percentage nitric oxide in NOX were not.

  7. Immunity of FPGA chips by direct injection


    Aurand, Tobias; Dawson, J.F.; Robinson, Martin Paul; Marvin, A.C.


    Immunity measurements of Xilinix XC3S200TQ144 and Altera EP3C10E144C7N FPGAs by direct injection are presented and the immunity of individual pins is shown to depend greatly on the load seen by nearby pins. The implications of this on in circuit immunity prediction are discussed.

  8. Burn injury reduces neutrophil directional migration speed in microfluidic devices.

    Directory of Open Access Journals (Sweden)

    Kathryn L Butler

    Full Text Available Thermal injury triggers a fulminant inflammatory cascade that heralds shock, end-organ failure, and ultimately sepsis and death. Emerging evidence points to a critical role for the innate immune system, and several studies had documented concurrent impairment in neutrophil chemotaxis with these post-burn inflammatory changes. While a few studies suggest that a link between neutrophil motility and patient mortality might exist, so far, cumbersome assays have prohibited exploration of the prognostic and diagnostic significance of chemotaxis after burn injury. To address this need, we developed a microfluidic device that is simple to operate and allows for precise and robust measurements of chemotaxis speed and persistence characteristics at single-cell resolution. Using this assay, we established a reference set of migration speed values for neutrophils from healthy subjects. Comparisons with samples from burn patients revealed impaired directional migration speed starting as early as 24 hours after burn injury, reaching a minimum at 72-120 hours, correlated to the size of the burn injury and potentially serving as an early indicator for concurrent infections. Further characterization of neutrophil chemotaxis using this new assay may have important diagnostic implications not only for burn patients but also for patients afflicted by other diseases that compromise neutrophil functions.

  9. Comparative study on direct burning of oil shale and coal (United States)

    Hammad, Ahmad; Al Asfar, Jamil


    A comparative study of the direct burning processes of oil shale and coal in a circulating fluidized bed (CFB) was done in this study using ANSYS Fluent software to solve numerically the governing equations of continuity, momentum, energy and mass diffusion using finite volume method. The model was built based on an existing experimental combustion burner unit. The model was validated by comparing the theoretical results of oil shale with proved experimental results from the combustion unit. It was found that the temperature contours of the combustion process showed that the adiabatic flame temperature was 1080 K for oil shale compared with 2260 K for coal, while the obtained experimental results of temperatures at various locations of burner during the direct burning of oil shale showed that the maximum temperature reached 962 K for oil shale. These results were used in economic and environmental analysis which show that oil shale may be used as alternative fuel for coal in cement industry in Jordan.


    Directory of Open Access Journals (Sweden)

    Usha Dev


    Full Text Available BACKGROUND AND OBJECTIVES: In patients with burn injury drug pharmacology will be altered and this poses special anaesthetic challenge when an subcutaneous injection of a non- depolarizing muscle relaxant occurs in such a patient. Small studies remain an important source of knowledge and hence this study aims to provide information on the anaesthetic management in a case of accidental subcutaneous injection of vecuronium bromide in a burns patient. PRESENTATION, DIAGNOSIS & MANAGEMENT: A 22 year young male with 4 days old hot water induced grade 1 burns involving 45% of body surface area was posted for burns dressing. Anaesthesia was induced with propofol and vecuronium bromide through an external jugular vein to aid tracheal intubation. As the patient was not anaesthetized even after 10 minutes routine check lead to the discovery of fullness at the tip of the intravenous catheter indicating an extravasation of the drugs. Hence the other external jugular vein was cannulated and the patient induced and intubated using propofol, sevoflurane, nitrous oxide and oxygen. The action of vecuronium outlasted the duration of surgery. So the patient continued to receive support of mechanical ventilation with nitrous oxide and oxygen. It took 130 minutes for the clinical signs of recovery from the muscle relaxant to manifest. He was then reversed & extubated with subsequent good recovery. CONCLUSION: Subcutaneous injection of these drugs poses problems of delayed onset of action and prolonged duration of action. In an inadvertent accidental subcutaneous 0.1 mg/kg vecuronium bromide injection in a patient with 4 day old 45% burns showed delayed onset action and prolonged neuromuscular blockade due to subcutaneous deposition of the drug which was managed with mechanical ventilation .The reported resistance to the action of NDMR drugs in patient with burns was not noticed here probably because of the age of the thermal injury.

  11. Mixture distribution measurement using laser induced breakdown spectroscopy in hydrogen direct injection stratified charge

    Energy Technology Data Exchange (ETDEWEB)

    Shudo, Toshio [Applied Energy System Group, Division of Energy and Environmental Systems, Hokkaido University, N13 W8 Kita-Ward, Sapporo, Hokkaido 060-8628 (Japan); Oba, Shuji [Mazda Motor Corporation, Hiroshima 730-8670 (Japan)


    Reduction in cooling loss due to the heat transfer from burning gas to the combustion chamber wall is very important for improving the thermal efficiency in hydrogen engines. The previous research has shown that the direct injection stratified charge can be a technique to reduce the cooling loss and improve thermal efficiency in hydrogen combustion. For effective reductions in cooling loss by the stratified charge, it is very important to know the relation between the fuel injection conditions and mixture distribution. The current research employs the laser induced breakdown spectroscopy as a method to measure the hydrogen concentration distribution in the direct injection stratified charge. Measurement of instantaneous local equivalence ratio by the method clears the characteristics of mixture formation in hydrogen direct injection stratified charge. This research also tries to actively control the mixture distribution using a split fuel injection. (author)

  12. Burns (United States)

    A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight, or radiation. Scalds from hot ... and gases are the most common causes of burns. Another kind is an inhalation injury, caused by ...

  13. Burn wound healing: present concepts, treatment strategies and future directions. (United States)

    Oryan, A; Alemzadeh, E; Moshiri, A


    Burns are the most extensive forms of soft tissue injuries occasionally resulting in extensive and deep wounds and death. Burns can lead to severe mental and emotional distress, because of excessive scarring and skin contractures. Treatment of burns has always been a difficult medical problem and many different methods have been used to treat such injuries, locally. Biofilms are a collection of microorganisms that delay wound healing. One of the new methods of prevention and treatment of burn wound infections is application of antimicrobials, which act on biofilms and prevent the wound infection. Biofilm initiates a persistent, low-grade, inflammatory response, impairing both the epithelialisation and granulation tissue formation. Skin grafts have been shown to dramatically reduce deaths from infection. However, grafting has considerable limitations. Such injuries are long-lasting and many patients suffer from chronic pain for a long time. Tissue engineering is a new approach in reducing the limitations of conventional treatments and producing a supply of immunologically tolerant artificial tissue, leading to a permanent solution for damaged tissues; such criteria make it a cost-effective and reliable treatment modality. To overcome the present limitations of burn wound healing, knowledge about the latest findings regarding healing mechanisms is important. Here the authors discuss the most important events regarding burn wound healing and review the latest treatment strategies that have been used for burn wounds from in vitro to clinical levels. Finally, we discuss the role of tissue engineering and regenerative medicine in the future of burn wound healing, modelling and remodelling.

  14. Blast furnace granular coal injection at Bethlehem Steel's Burns Harbor Plant

    Energy Technology Data Exchange (ETDEWEB)

    D. Gregory Hill; Leo I.E. Makovsky; Thomas A. Sarkus; Howard G. McIlvried [Bethlehem Steel Corporation, Chesterton, IN (USA)


    The paper discusses the demonstration of the British Steel/CPC-Macawber Blast Furnace Granular Coal Injection (BFGCI) technology that was installed on the blast furnaces at Bethlehem Steel's Burns Harbor Plant in Indiana as a highly successful Clean Coal Technology project, cofunded by the U.S. Department of Energy. In the BFGCI process, granular coal (10%-30% through a 200-mesh screen) is injected into a blast furnace as a fuel supplement to decrease coke requirements, thus reducing costs. Tests run to determine the effect of process variables on furnace operations showed that granular coal works as well as pulverized coal and is easier to handle and cheaper to produce because of reduced grinding costs.

  15. CMOS Direct-Injection Divide-by-3 Injection-Locked Frequency Dividers

    Institute of Scientific and Technical Information of China (English)

    Chia-Wei; Chang; Jhin-Fang; Huang; Sheng-Lyang; Jang; Ying-Hsiang; Liao; Miin-Horng; Juang


    <正>This paper proposes CMOS LC-tank divide-by-3 injection locked frequency dividers(ILFDs)fabricated in 0.18μn and 90nm CMOS process and describes the circuit design,operation principle and measurement results of the ILFDs.The ILFDs use two injection series-MOSFETs across the LC resonator and a differential injection signal is applied to the gates of injection MOSFETs.The direct-injection divide-by-3 ILFDs are potential for radio-frequency application and can have wide locking range.

  16. Burns (United States)

    To help prevent burns: Install smoke alarms in your home. Check and change batteries regularly. Teach children about fire safety and the danger of matches and fireworks. Keep children from climbing on top of a stove ...

  17. Direct detection of oxygen free radicals produced in theviscera of burned rats using electron paramagneticresonance spectroscopy

    Institute of Scientific and Technical Information of China (English)

    路卫; 陈玉琳; 夏照帆


    Objective: To detect superoxide anion (O-2) signalsin the heart, liver, lung and kidney tissues after burns.Methods: Twenty-four male rats were randomizedinto 4 groups. The rats of experimental groups wereimmersed in 100℃ water for 15 seconds and 25% third-degree burn was created. Thoracotomy or laparotomy wasperformed at 5, 10, 15, 20 and 30 minutes after burn, andspecimens of the heart, lung, liver kidney were obtained forburned rats. The specimens were then preserved in liquidnitrogen for cryo-preservation and detected immediatelyusing EPR.Results: The signals of superoxide O radicalappeared in the heart, lung, liver and kidney specimens10-15 minutes after burn.Conclusions: There is a direct evidence of oxygen freeradicals (OFRs) injury to viscera of burned rats between10-15 minutes after burn.

  18. Effects of Fischer-Tropsch diesel fuel on combustion and emissions of direct injection diesel engine

    Institute of Scientific and Technical Information of China (English)

    Yongcheng HUANG; Shangxue WANG; Longbao ZHOU


    Effects of Fischer-Tropsch (F-T) diesel fuel on the combustion and emission characteristics of a single-cylinder direct injection diesel engine under different fuel delivery advance angles were investigated. The experi-mental results show that F-T diesel fuel exhibits shorter ignition delay, lower peak values of premixed burning rate, lower combustion pressure and pressure rise rate, and higher peak value of diffusion burning rate than con-ventional diesel fuel when the engine remains unmodified. In addition, the unmodified engine with F-T diesel fuel has lower brake specific fuel consumption and higher effective thermal efficiency, and presents lower HC, CO, NOx and smoke emissions than conventional diesel fuel. When fuel delivery advance angle is retarded by 3 crank angle degrees, the combustion duration is obviously shor-tened; the peak values of premixed burning rate, the com-bustion pressure and pressure rise rate are further reduced; and the peak value of diffusion burning rate is further increased for F-T diesel fuel operation, Moreover, the retardation of fuel delivery advance angle results in a further significant reduction in NOx emissions with no penalty on specific fuel consumption and with much less penalty on HC, CO and smoke emissions.

  19. Direct Fuel Injection of LPG in Small Two-Stroke Engines

    Directory of Open Access Journals (Sweden)

    Yew Heng Teoh


    Full Text Available The commonly used carburetted two-stroke engines in developing countries have high exhaust emission and poor fuel efficiency. To meet more rigid emissions requirements, two-stroke vehicles are typically phase out in favour of four-stroke engines. The problems of ubiquitous legacy two-stroke vehicles remain unsolved by these measures and they are likely to be a major source of transport for many years to come. A number of technologies are available for solving the problems associated with two-stroke engines such as catalytic after-treatment and direct fuel injection (DI. However, these solutions are relatively high cost and have shown only slow market acceptance for applications in developing countries. Research in recent years has demonstrated that direct fuel injection is a well developed and readily deployable solution to existing two-stroke engines. Gaseous fuels such as Liquefied Petroleum Gas (LPG are considered a promising energy source and in many countries provide fuel cost savings. LPG coupled with DI two-stroke technologies, is expected to be clean and cost effective retrofit solution for two-stroke engines. In this research project, direct injection (DI of Liquefied Petroleum Gas (LPG is introduced and tested on a typical two-stroke engine. Results of in cylinder combustion pressure translated to fuel mass fraction burned, engine performance and exhaust emissions are taken and compared for various injection timings from premixed (early injection to fully direct injection mode (late injection. Results show that DI of LPG effectively reduces exhaust hydrocarbon and can substantially improve the fuel economy of two-stroke engines.

  20. Performance and combustion characteristics of a direct injection SI hydrogen engine

    Energy Technology Data Exchange (ETDEWEB)

    Mohammadi, Ali [Engine Technology, Powertrain, Toyota Motor Europe, Technical centre Hoge Wei 33 Zaventem 1930 (Belgium); Shioji, Masahiro; Nakai, Yasuyuki; Ishikura, Wataru [Graduate School of Energy Science, Kyoto University, Yoshida-honmachi Sakyo-ku Kyoto 605-8501 (Japan); Tabo, Eizo [Environmental and Technical Affairs Department, Mitsubishi Motors Co., 5-33-8 Shiba Minatoku Tokyo 108-8401 (Japan)


    Hydrogen with low spark-energy requirement, wide flammability range and high burning velocity is an important candidate for being used as fuel in spark-ignition engines. It also offers CO{sub 2} and HC free combustion and lean operation resulting in lower NO{sub x} emissions. However, well examined external mixing of hydrogen with intake air causes backfire and knock especially at higher engine loads. In addition, low heating value per unit of volume of hydrogen limits the maximum output power. In this study, attention was paid to full usage of hydrogen advantage employing internal mixing method. Hydrogen was directly injected into cylinder of a single-cylinder test engine using a high-pressure gas injector and effects of injection timing and spark timing on engine performance and NO{sub x} emission were investigated under wide engine loads. The results indicate that direct injection of hydrogen prevents backfire, and that high thermal efficiency and output power can be achieved by hydrogen injection during late compression stroke. Moreover, by further optimization of the injection timing for each engine load, NO{sub x} emission can be reduced under the high engine output conditions. (author)

  1. Combustion strategies for a SI direct injection natural gas engine; Darstellung verschiedener Betriebsstrategien an einem Erdgasmotor mit innerer Gemischbildung

    Energy Technology Data Exchange (ETDEWEB)

    Bohatsch, S.; Hoffmann, B.; Ferrari, A.; Chiodi, M.; Berner, H.J.; Bargende, M.


    Natural gas as a fuel for internal combustion engines is a combustion technology showing great promise for the reduction of CO{sub 2} and particulate matter. To demonstrate the potential of natural gas direct injection some experimental investigations were carried out using a single-cylinder engine with lateral injector position. For this different injection valve nozzles, piston crown geometries as well as operating strategies were investigated. First experimental results accompanied by additional CFD-simulation show that it is possible to control the burn rate by injection induced turbulence. Furthermore the results show that a short mixture preparation distance between injection nozzle and spark plug is necessary because of the poor fuel penetration during the injection process which is typical for gaseous fuels. (orig.)

  2. Investigations on high speed directly modulated microdisk lasers accounting for radial carrier hole burning (United States)

    Huang, Yong-Zhen; Lv, Xiao-Meng; Zou, Ling-Xiu; Long, Heng; Xiao, Jin-Long; Yang, Yue-De; Du, Yun


    High-speed modulation characteristics are investigated for microdisk lasers theoretically and experimentally. In rate equation analysis, the microdisk resonator is radially divided into two regions under uniform carrier density approximation in each region. The injection current profile, carrier spatial hole burning, and diffusion are accounted for in the evaluation of small-signal modulation curves and the simulation of large-signal responses. The numerical results indicate that a wide mode field pattern in radial direction has merit for high-speed modulation, which is expected for coupled modes in the microdisk lasers connected with an output waveguide. For a 15-μm-radius microdisk laser connected with a 2-μm-wide output waveguide, the measured small-signal response curves with a low-frequency roll-off are well in agreement with the simulated result at a 2-μm radial width for the mode intensity distribution. The resonant frequencies of 7.2, 5.9, and 3.9 GHz are obtained at the temperatures of 287, 298, and 312 K from the small-signal response curves, and clear eye diagrams at 12.5 Gb/s with an extinction ratio of 6.1 dB are observed for the microdisk laser at the biasing current of 38 mA and 287 K.

  3. 76 FR 8661 - Airworthiness Directives; Lycoming Engines, Fuel Injected Reciprocating Engines (United States)


    ...-14-07, Amendment 39-15602 (73 FR 39574), for certain fuel injected reciprocating engines manufactured... Directives; Lycoming Engines, Fuel Injected Reciprocating Engines AGENCY: Federal Aviation Administration... airworthiness directive (AD) that applies to certain fuel injected reciprocating engines manufactured...

  4. On the relationship between cardboard burning in a sunshine recorder and the direct solar irradiance. (United States)

    Sanchez, A.; Calbó, J.; González, J. A.


    Since the end of XIX century, the Campbell-Stokes recorder (CSR) has been the instrument used to measure the insolation (hours of sunshine during per day). Due to the large number of records that exist worldwide (some of them extending over more than 100 years), valuable climatic information can be extracted from them. There are various articles that relate the insolation with the cloudiness and the global solar irradiation (Angstrom-Prescott type formulas). Theoretically, the insolation is defined as the number of hours that direct solar irradiance (DSI) exceeds 120 W/m2, thus corresponding to the total length of the burning in the bands. The width of the burn has not been well studied, so the aim of this research is to relate this width, first with the DSI and then, with other variables. The research was carried out in Girona (NE Spain) for a period extending since February 2011. A CSR from Thies Clima and a pyrheliometer from Kipp&Zonen were used to measure insolation and the direct solar irradiance. Other meteorological variables were also stored for the study. For each band, we made two independent measurements of the width of the burn every 10 minutes: first, we measured directly the width of the perforated portion of the burn; second, we measured the width of the burn after applying a digital image process that increases the contrast of the burn. The burn in a band has a direct relationship with the DSI. Specifically, correlation coefficients of the perforation width and the burning width with DSI were 0.838 and 0.864 respectively. However, we found that there are times when despite of DSI is as high as 400 W/m2 (i.e. much greater than 120 W/m2), there is no burn in the band. Contrarily, sometimes a burn occurs with almost no DSI. Furthermore, a higher DSI does not always correspond to a wider burn of the band. Because of this, we consider that characteristics of band burns must also depend on other meteorological variables (temperature, humidity...). The

  5. NOx reduction by ozone injection and direct plasma treatment

    DEFF Research Database (Denmark)

    Stamate, Eugen; Salewski, Mirko


    NOx reduction by ozone injection and direct plasma treatment is investigated for different process parameters in a 6 m long serpentine reactor. Several aspects including the role of mixing scheme, water vapours, steep temperature gradient and time dependet NOx levels are taken into consideration....... The process chemistry is monitored by FTIR, chemiluminiscence and absorbtion spectroscopy. The kinetic mechanism is also investigated in 3D simulations....

  6. Closed-Loop Control of Chemical Injection Rate for a Direct Nozzle Injection System

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    Xiang Cai


    Full Text Available To realize site-specific and variable-rate application of agricultural pesticides, accurately metering and controlling the chemical injection rate is necessary. This study presents a prototype of a direct nozzle injection system (DNIS by which chemical concentration transport lag was greatly reduced. In this system, a rapid-reacting solenoid valve (RRV was utilized for injecting chemicals, driven by a pulse-width modulation (PWM signal at 100 Hz, so with varying pulse width the chemical injection rate could be adjusted. Meanwhile, a closed-loop control strategy, proportional-integral-derivative (PID method, was applied for metering and stabilizing the chemical injection rate. In order to measure chemical flow rates and input them into the controller as a feedback in real-time, a thermodynamic flowmeter that was independent of chemical viscosity was used. Laboratory tests were conducted to assess the performance of DNIS and PID control strategy. Due to the nonlinear input–output characteristics of the RRV, a two-phase PID control process obtained better effects as compared with single PID control strategy. Test results also indicated that the set-point chemical flow rate could be achieved within less than 4 s, and the output stability was improved compared to the case without control strategy.

  7. Performance of CO2 enrich CNG in direct injection engine (United States)

    Firmansyah, W. B.; Ayandotun, E. Z.; Zainal, A.; Aziz, A. R. A.; Heika, M. R.


    This paper investigates the potential of utilizing the undeveloped natural gas fields in Malaysia with high carbon dioxide (CO2) content ranging from 28% to 87%. For this experiment, various CO2 proportions by volume were added to pure natural gas as a way of simulating raw natural gas compositions in these fields. The experimental tests were carried out using a 4-stroke single cylinder spark ignition (SI) direct injection (DI) compressed natural gas (CNG) engine. The tests were carried out at 180° and 300° before top dead centre (BTDC) injection timing at 3000 rpm, to establish the effects on the engine performance. The results show that CO2 is suppressing the combustion of CNG while on the other hand CNG combustion is causing CO2 dissociation shown by decreasing CO2 emission with the increase in CO2 content. Results for 180° BTDC injection timing shows higher performance compared to 300° BTDC because of two possible reasons, higher volumetric efficiency and higher stratification level. The results also showed the possibility of increasing the CO2 content by injection strategy.

  8. Attempt of lean burn of a 4 cycle gasoline engine by the aid of low pressure air assisted in-cylinder injection; Tonai kuki nenryo funsha ni yoru lean burn no kokoromi

    Energy Technology Data Exchange (ETDEWEB)

    Hatakeyama, S.; Kondo, M.; Sekiya, Y.; Murayama, T. [Hokkaido Automotive Engineering College, Hokkaido (Japan)


    Comparable performance and exhaust emission with conventional carburetor was obtained by a low Pressure air assisted in-cylinder injection system. And lean burn of idling and light load operation till A/F=70 was realized by installing a spark Plug and a reed type injection nozzle in a divided combustion chambaer of a 4 cycle gasoline engine. 2 refs., 10 figs.

  9. Nonlinear Burn Control in Tokamaks using Heating, Non-axisymmetric Magnetic Fields, Isotopic fueling and Impurity injection (United States)

    Pajares, Andres; Schuster, Eugenio


    Plasma density and temperature regulation in future tokamaks such as ITER is arising as one of the main problems in nuclear-fusion control research. The problem, known as burn control, is to regulate the amount of fusion power produced by the burning plasma while avoiding thermal instabilities. Prior work in the area of burn control considered different actuators, such as modulation of the auxiliary power, modulation of the fueling rate, and controlled impurity injection. More recently, the in-vessel coil system was suggested as a feasible actuator since it has the capability of modifying the plasma confinement by generating non-axisymmetric magnetic fields. In this work, a comprehensive, model-based, nonlinear burn control strategy is proposed to integrate all the previously mentioned actuators. A model to take into account the influence of the in-vessel coils on the plasma confinement is proposed based on the plasma collisionality and the density. A simulation study is carried out to show the capability of the controller to drive the system between different operating points while rejecting perturbations. Supported by the US DOE under DE-SC0010661.

  10. The effect of water injection on nitric oxide emissions of a gas turbine combustor burning ASTM Jet-A fuel (United States)

    Marchionna, N. R.; Diehl, L. A.; Trout, A. M.


    Tests were conducted to determine the effect of water injection on oxides of nitrogen (NOx) emissions of a full annular, ram induction gas turbine combustor burning ASTM Jet-A fuel. The combustor was operated at conditions simulating sea-level takeoff and cruise conditions. Water at ambient temperature was injected into the combustor primary zone at water-fuel ratios up to 2. At an inlet-air temperature of 589 K (600 F) water injection decreased the NOx emission index at a constant exponential rate: NOx = NOx (o) e to the -15 W/F power (where W/F is the water-fuel ratio and NOx(o) indicates the value with no injection). The effect of increasing combustor inlet-air temperature was to decrease the effect of the water injection. Other operating variables such as pressure and reference Mach number did not appear to significantly affect the percent reduction in NOx. Smoke emissions were found to decrease with increasing water injection.

  11. Direct Injection Compression Ignition Diesel Automotive Technology Education GATE Program

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Carl L


    The underlying goal of this prqject was to provide multi-disciplinary engineering training for graduate students in the area of internal combustion engines, specifically in direct injection compression ignition engines. The program was designed to educate highly qualified engineers and scientists that will seek to overcome teclmological barriers preventing the development and production of cost-effective high-efficiency vehicles for the U.S. market. Fu1iher, these highly qualified engineers and scientists will foster an educational process to train a future workforce of automotive engineering professionals who are knowledgeable about and have experience in developing and commercializing critical advanced automotive teclmologies. Eight objectives were defmed to accomplish this goal: 1. Develop an interdisciplinary internal co1nbustion engine curriculum emphasizing direct injected combustion ignited diesel engines. 2. Encourage and promote interdisciplinary interaction of the faculty. 3. Offer a Ph.D. degree in internal combustion engines based upon an interdisciplinary cuniculum. 4. Promote strong interaction with indusuy, develop a sense of responsibility with industry and pursue a self sustaining program. 5. Establish collaborative arrangements and network universities active in internal combustion engine study. 6. Further Enhance a First Class educational facility. 7. Establish 'off-campus' M.S. and Ph.D. engine programs of study at various indusuial sites. 8. Extend and Enhance the Graduate Experience.

  12. Direct injection of superheated steam for continuous hydrolysis reaction

    KAUST Repository

    Wang, Weicheng


    The primary intent for previous continuous hydrolysis studies was to minimize the reaction temperature and reaction time. In this work, hydrolysis is the first step of a proprietary chemical process to convert lipids to sustainable, drop-in replacements for petroleum based fuels. To improve the economics of the process, attention is now focused on optimizing the energy efficiency of the process, maximizing the reaction rate, and improving the recovery of the glycerol by-product. A laboratory-scale reactor system has been designed and built with this goal in mind.Sweet water (water with glycerol from the hydrolysis reaction) is routed to a distillation column and heated above the boiling point of water at the reaction pressure. The steam pressure allows the steam to return to the reactor without pumping. Direct injection of steam into the hydrolysis reactor is shown to provide favorable equilibrium conditions resulting in a high quality of FFA product and rapid reaction rate, even without preheating the inlet water and oil and with lower reactor temperatures and lower fresh water demand. The high enthalpy of the steam provides energy for the hydrolysis reaction. Steam injection offers enhanced conditions for continuous hydrolysis of triglycerides to high-purity streams of FFA and glycerol. © 2012 Elsevier B.V.

  13. Characteristics of pressure wave in common rail fuel injection system of high-speed direct injection diesel engines

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Herfatmanesh


    Full Text Available The latest generation of high-pressure common rail equipment now provides diesel engines possibility to apply as many as eight separate injection pulses within the engine cycle for reducing emissions and for smoothing combustion. With these complicated injection arrangements, optimizations of operating parameters for various driving conditions are considerably difficult, particularly when integrating fuel injection parameters with other operating parameters such as exhaust gas recirculation rate and boost pressure together for evaluating calibration results. Understanding the detailed effects of fuel injection parameters upon combustion characteristics and emission formation is therefore particularly critical. In this article, the results and discussion of experimental investigations on a high-speed direct injection light-duty diesel engine test bed are presented for evaluating and analyzing the effects of main adjustable parameters of the fuel injection system on all regulated emission gases and torque performance. Main injection timing, rail pressure, pilot amount, and particularly pilot timing have been examined. The results show that optimization of each of those adjustable parameters is beneficial for emission reduction and torque improvement under different operating conditions. By exploring the variation in the interval between the pilot injection and the main injection, it is found that the pressure wave in the common rail has a significant influence on the subsequent injection. This suggests that special attentions must be paid for adjusting pilot timing or any injection interval when multi-injection is used. With analyzing the fuel amount oscillation of the subsequent injections to pilot separation, it demonstrates that the frequency of regular oscillations of the actual fuel amount or the injection pulse width with the variation in pilot separation is always the same for a specified fuel injection system, regardless of engine speed

  14. Improved direct torque control of induction motor with dither injection

    Indian Academy of Sciences (India)

    R K Behera; S P Das


    In this paper, a three-level inverter-fed induction motor drive operating under Direct Torque Control (DTC) is presented. A triangular wave is used as dither signal of minute amplitude (for torque hysteresis band and flux hysteresis band respectively) in the error block. This method minimizes flux and torque ripple in a three-level inverter fed induction motor drive while the dynamic performance is not affected. The optimal value of dither frequency and magnitude is found out under free running condition. The proposed technique reduces torque ripple by 60% (peak to peak) compared to the case without dither injection, results in low acoustic noise and increases the switching frequency of the inverter. A laboratory prototype of the drive system has been developed and the simulation and experimental results are reported.

  15. Design of an RFQ for direct plasma injection scheme

    Institute of Scientific and Technical Information of China (English)

    ZHANG Zhouli; R.A.Jameson; ZHAO Hongwei; XU Zhe; LIU Yong; ZHANG Shenghu; ZHANG Cong; SUN Liepeng; MEI Lirong; SHEN Xiaokang


    A high current radio frequency quadrupole (RFQ) is being studied at the Institute of Modern Physics,Chinese Academy of Sciences (IMP,CAS) for the direct plasma injection scheme (DPIS).Because of the strong space charge of beams from laser ion source,the beam dynamics design of the RFQ has been carried out with a new code,which can deal with space charge effectively.The design of the RFQ structure is performed with an electromagnetic simulation code and the determination of parameters of the structure has been done to maximize the shunt impedance when the frequency is kept fixed.The influences of dipole mode effect and flatness on beams were also discussed.

  16. Ducted combustion chamber for direct injection engines and method (United States)

    Mueller, Charles


    An internal combustion engine includes an engine block having a cylinder bore and a cylinder head having a flame deck surface disposed at one end of the cylinder bore. A piston connected to a rotatable crankshaft and configured to reciprocate within the cylinder bore has a piston crown portion facing the flame deck surface such that a combustion chamber is defined within the cylinder bore and between the piston crown and the flame deck surface. A fuel injector having a nozzle tip disposed in fluid communication with the combustion chamber has at least one nozzle opening configured to inject a fuel jet into the combustion chamber along a fuel jet centerline. At least one duct defined in the combustion chamber between the piston crown and the flame deck surface has a generally rectangular cross section and extends in a radial direction relative to the cylinder bore substantially along the fuel jet centerline.

  17. Turbulence-combustion interaction in direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Bencherif Mohamed


    Full Text Available The experimental measures of chemical species and turbulence intensity during the closed part of the engine combustion cycle are today unattainable exactly. This paper deals with numerical investigations of an experimental direct injection Diesel engine and a commercial turbocharged heavy duty direct injection one. Simulations are carried out with the kiva3v2 code using the RNG (k-ε model. A reduced mechanism for n-heptane was adopted for predicting auto-ignition and combustion processes. From the calibrated code based on experimental in-cylinder pressures, the study focuses on the turbulence parameters and combustion species evolution in the attempt to improve understanding of turbulence-chemistry interaction during the engine cycle. The turbulent kinetic energy and its dissipation rate are taken as representative parameters of turbulence. The results indicate that chemistry reactions of fuel oxidation during the auto-ignition delay improve the turbulence levels. The peak position of turbulent kinetic energy coincides systematically with the auto-ignition timing. This position seems to be governed by the viscous effects generated by the high pressure level reached at the auto-ignition timing. The hot regime flame decreases rapidly the turbulence intensity successively by the viscous effects during the fast premixed combustion and heat transfer during other periods. It is showed that instable species such as CO are due to deficiency of local mixture preparation during the strong decrease of turbulence energy. Also, an attempt to build an innovative relationship between self-ignition and maximum turbulence level is proposed. This work justifies the suggestion to determine otherwise the self-ignition timing.

  18. Effects of injection timing on nonlinear dynamics of the combustion process in the lean-burn premixed natural gas engine (United States)

    Ding, Shun-Liang; Song, En-Zhe; Yang, Li-Ping; Yao, Chong; Ma, Xiu-Zhen


    The nonlinear dynamics of the combustion process in the lean-burn premixed natural gas engine are studied in this paper. Based on nonlinear dynamic theory, the complexity of the combustion process is analyzed under different injection timing conditions. The phase spaces are reconstructed for the experimentally obtained in-cylinder pressure real-time series and the return maps are plotted for the IMEP time series. The results of phase space reconstruction manifest that the attractors are limited to the finite range in the reconstructed phase space. The attractors have a folded and twist geometry structure. The attractors under medium injection timing conditions are looser and more complex. The return maps indicate the coexistence of the stochastic and deterministic components in the patterns combustion process. With the injection timing increasing, there are both a transition from stochastic to deterministic and a transition from deterministic to stochastic, forming the region of deterministic behavior. The largest Lyapunov exponents (LLE) for in-cylinder pressure time series are calculated and the coefficients of variations (COV) of IMEP are also analyzed. The results express that the LLE values are positive. There are a "steep increase" and a "steep decrease" for the LLE and COV values as the injection timing increasing.

  19. LPG gaseous phase electronic port injection on performance, emission and combustion characteristics of Lean Burn SI Engine (United States)

    Bhasker J, Pradeep; E, Porpatham


    Gaseous fuels have always been established as an assuring way to lessen emissions in Spark Ignition engines. In particular, LPG resolved to be an affirmative fuel for SI engines because of their efficient combustion properties, lower emissions and higher knock resistance. This paper investigates performance, emission and combustion characteristics of a microcontroller based electronic LPG gaseous phase port injection system. Experiments were carried out in a single cylinder diesel engine altered to behave as SI engine with LPG as fuel at a compression ratio of 10.5:1. The engine was regulated at 1500 rpm at a throttle position of 20% at diverse equivalence ratios. The test results were compared with that of the carburetion system. The results showed that there was an increase in brake power output and brake thermal efficiency with LPG gas phase injection. There was an appreciable extension in the lean limit of operation and maximum brake power output under lean conditions. LPG injection technique significantly reduces hydrocarbon and carbon monoxide emissions. Also, it extremely enhances the rate of combustion and helps in extending the lean limit of LPG. There was a minimal increase of NOx emissions over the lean operating range due to higher temperature. On the whole it is concluded that port injection of LPG is best suitable in terms of performance and emission for LPG fuelled lean burn SI engine.

  20. Scaling of the direct ECC bypass during LBLOCA reflood phase with direct vessel injection system

    Energy Technology Data Exchange (ETDEWEB)

    Yun, B.J.; Kwon, T.S.; Song, C.H.; Jeong, J.J. [Korea Atomic Energy Research Inst., Taejon (Korea, Republic of); Cho, H.K.; Park, G.C. [Seoul National Univ., Dept. of Nuclear Engineering (Korea, Republic of)


    As one of the advanced design features of the Korea next generation reactor, direct vessel injection (DVI) system is being considered instead of conventional cold leg injection (CLI) system. It is known that the DVI system greatly enhances the reliability of the emergency core cooling (ECC) system. However, there is still a dispute on its performance in terms of water delivery to the reactor core during the reflood period of a large-break loss-of-coolant accident (LOCA). Thus, experimental validation is under progress. In this paper, a new scaling method, using time and velocity reduced linear scaling law, is suggested for the design of a scaled-down experimental facility to investigate the direct ECC bypass phenomena in PWR downcomer. (authors)

  1. Direct Energy Exchange Enhancement in Distributed Injection Light Gas Launchers

    Energy Technology Data Exchange (ETDEWEB)

    Alger, T W; Finucane, R G; Hall, J P; Penetrante, B M; Uphaus, T M


    initially contained in the reservoir. This results deserves emphasis: whereas conventional guns apply a few percent of the reservoir pressure to a fast moving projectile, our design is paradoxically capable of applying nearly double the contained pressure. We later confirmed this experimental result analytically and related it to a type of direct energy exchange between unsteady fluid flows. This physical approach was the basis for the German V-1 ''buzz bomb'' of World War II; it has been applied to a limited number of commercial applications. (This work should not be confused with the German WWII distributed injection missile launchers.) Direct fluid-energy exchange has not previously been applied to any gas-launcher technology. As a result of these discoveries, we estimate that a practical, 15 km/s, high-velocity launcher could be built using our direct-energy-exchange, distributed-injection approach. However, the radical nature of the results, the lack of confirming or allied work being carried out anywhere else, and the fact that it would take extensive time and resources to demonstrate targeted performance precluded further development. We plan to submit the results to a refereed journal to ensure that the work will not be lost to the launcher community.

  2. Direct observation of aqueous secondary organic aerosol from biomass-burning emissions (United States)

    Gilardoni, Stefania; Massoli, Paola; Paglione, Marco; Giulianelli, Lara; Carbone, Claudio; Rinaldi, Matteo; Decesari, Stefano; Sandrini, Silvia; Costabile, Francesca; Gobbi, Gian Paolo; Chiara Pietrogrande, Maria; Visentin, Marco; Scotto, Fabiana; Fuzzi, Sandro; Facchini, Maria Cristina


    The mechanisms leading to the formation of secondary organic aerosol (SOA) are an important subject of ongoing research for both air quality and climate. Recent laboratory experiments suggest that reactions taking place in the atmospheric liquid phase represent a potentially significant source of SOA mass. Here, we report direct ambient observations of SOA mass formation from processing of biomass-burning emissions in the aqueous phase. Aqueous SOA (aqSOA) formation is observed both in fog water and in wet aerosol. The aqSOA from biomass burning contributes to the “brown” carbon (BrC) budget and exhibits light absorption wavelength dependence close to the upper bound of the values observed in laboratory experiments for fresh and processed biomass-burning emissions. We estimate that the aqSOA from residential wood combustion can account for up to 0.1-0.5 Tg of organic aerosol (OA) per y in Europe, equivalent to 4-20% of the total OA emissions. Our findings highlight the importance of aqSOA from anthropogenic emissions on air quality and climate.

  3. Spin Injection from Ferromagnetic Metal Directly into Non-Magnetic Semiconductor under Different Injection Currents

    Institute of Scientific and Technical Information of China (English)

    DENG Ning; TANG Jian-Shi; ZHANG Lei; ZHANG Shu-Chao; CHEN Pei-Yi


    @@ For ferromagnetic metal(FM)/semiconductor(SC)structure with ohmic contact,the effect of carrier polarization in the semiconductor combined with drift part of injection current on current polarization is investigated.Based on the general model we established here,spin injection efficiency under different injection current levels is calculated.Under a reasonable high injection current,current polarization in the semiconductor is actually much larger than that predicted by the conductivity mismatch model because the effect of carrier polarization is enhanced by the increasing drift current.An appreciable current polarization of 1% could be achieved for the FM/SC structure via ohmic contact,which means that efficient spin injection from FM into SC via ohmic contact is possible.The reported dependence of current polarization on temperature is verified quantitatively.To achieve even larger spin injection efficiency,a gradient doping semiconductor is suggested to enhance the drift current effect.

  4. Admission Cell Free DNA as a Prognostic Factor in Burns: Quantification by Use of a Direct Rapid Fluorometric Technique

    Directory of Open Access Journals (Sweden)

    Yaron Shoham


    Full Text Available Background. Despite great advances in the treatment of burn patients, useful prognostic markers are sparse. During the past years there has been increasing interest in circulating plasma cell free DNA as a potential marker for tissue injury. We have developed a rapid direct fluorescent assay for cell free DNA quantification that allows obtaining accurate, fast, and inexpensive measurements. Objective. To use this technique for measuring plasma cell free DNA levels in burn patients and to further explore the use of cell free DNA as a potential marker of patient outcome in burns. Methods. Cell free DNA levels obtained from 14 burn victims within 6 hours of injury and 14 healthy controls were quantified by a direct rapid fluorometric assay. Results. Patient admission cell free DNA levels were significantly elevated compared with that of controls (1797 ± 1523 ng/mL versus 374 ± 245 ng/mL, P=0.004. There are statistically significant correlations between cell free DNA admission levels and burn degree (Spearman’s correlation = 0.78, P=0.001, total body surface area (Spearman’s correlation = 0.61, P=0.02, and total burn volume (Spearman’s correlation = 0.64, P=0.014. Conclusions. Admission cell free DNA levels can serve as a prognostic factor in burns and future routine use can be made possible by use of our direct rapid fluorometric assay.

  5. Local and distant chemical burns due to cetrimide injection in a massive dose

    Directory of Open Access Journals (Sweden)

    Kumar S


    Full Text Available Sixty ml of 20% cetrimide shampoo solution was injected subcutaneously around the left elbow by a drug addict to commit suicide. Edema, blisters with skip areas and, cellulitis were noted within 6 hours, not only around the site of the injection but also upto the wrist and the pectoral region. Muscles were protected by the tough deep fascia. There was no systemic toxidcity despite receiving at least 4 times the reported fatal dose. The patient was treated with multiple fasciotomies, broad spectrum antibiotics, an atory drugs, iunb elevation and daily dressings, followed by secondary suturing of fasciotomy wounds when the limb edema regressed. The cutaneous bums healed without needing skin grafts.

  6. Assessment of in-furnace dry sorbent injection experimental results burning low sulphur content coals

    Energy Technology Data Exchange (ETDEWEB)

    Collado, F.J. [Univ. de Zaragoza (Spain)


    In an effort to adjust the SO{sub 2} emissions of coal power stations to the current air pollutant standards, established by the EC, flue gas desulfurization tests with in-furnace dry sorbent injection technology in the Spanish coal power station ``Litoral`` (tangentially-fired) were performed. The measured retentions were lower than predicted through a one-dimensional model. Then, it was thought that a CFD 3D simulation of the injection would help to understand the complex relationships of the process. The simulation was divided in two stages: in the first one, the turbulent velocity and the temperature field were solved. In the second one, representative sorbent particles were injected in the turbulent field previously solved, the focus of this work being the global sulphur capture modeling and its validation through the experimental measurements obtained. After a revision of the models proposed in the specialized literature, a global sulfation model is chosen, being compared with the experimental data obtained in the power station. Because of the main results of this work, the authors can highlight the testing of the laboratory-scale correlations against full-scale results, and can mitigate the difficulty of estimating the actual temperature profile by experimenting with the particle and its residence time without the aid of a CFD code.

  7. Hydrogen Gas as a Fuel in Direct Injection Diesel Engine (United States)

    Dhanasekaran, Chinnathambi; Mohankumar, Gabriael


    Hydrogen is expected to be one of the most important fuels in the near future for solving the problem caused by the greenhouse gases, for protecting environment and saving conventional fuels. In this study, a dual fuel engine of hydrogen and diesel was investigated. Hydrogen was conceded through the intake port, and simultaneously air and diesel was pervaded into the cylinder. Using electronic gas injector and electronic control unit, the injection timing and duration varied. In this investigation, a single cylinder, KIRLOSKAR AV1, DI Diesel engine was used. Hydrogen injection timing was fixed at TDC and injection duration was timed for 30°, 60°, and 90° crank angles. The injection timing of diesel was fixed at 23° BTDC. When hydrogen is mixed with inlet air, emanation of HC, CO and CO2 decreased without any emission (exhaustion) of smoke while increasing the brake thermal efficiency.

  8. Separate direct injection of diesel and ethanol: A numerical analysis

    Directory of Open Access Journals (Sweden)

    Burnete Nicolae V.


    Full Text Available The purpose of this study is to investigate the theoretical possibility of using a pilot diesel injection for the auto-ignition of a main ethanol injection in a compression ignition engine. To this effect a predictive simulation model has been built based on experimental results for a diesel cycle (pilot and main injection at 1500 and 2500 min–1, respectively. For every engine speed, in addition to the diesel reference cycle, two more simulations were done: one with the same amount of fuel injected into the cylinder and one with the same amount of energy, which required an increase in the quantity of ethanol proportional to the ratio of its lower heating value and that of diesel. The simulations showed that in all cases the pilot diesel led to the auto-ignition of ethanol. The analysis of the in-cylinder traces at 1500 min–1 showed that combustion efficiency is improved, the peak temperature value decrease with approximately 240 K and, as a result, the NO emissions are 3.5-4 times lower. The CO and CO2 values depend on the amount of fuel injected into the cylinder. At 2500 min–1 there are similar trends but with the following observations: the ignition delay increases, while the pressure and temperature are lower.

  9. Dry low NOx combustion system with pre-mixed direct-injection secondary fuel nozzle (United States)

    Zuo, Baifang; Johnson, Thomas; Ziminsky, Willy; Khan, Abdul


    A combustion system includes a first combustion chamber and a second combustion chamber. The second combustion chamber is positioned downstream of the first combustion chamber. The combustion system also includes a pre-mixed, direct-injection secondary fuel nozzle. The pre-mixed, direct-injection secondary fuel nozzle extends through the first combustion chamber into the second combustion chamber.


    Directory of Open Access Journals (Sweden)

    Zbigniew Czyż


    Full Text Available The paper presents CFD analysis of fuel flow in the CNG injector. The issues such a pressure drop along an injector channel, mass flow through the key sections of the injector geometry, flow rates, the impact of the needle shape on the deflection of the sprayed gas cone and the impact of the wall head are analyzed in the article. The simulation was made in the transient states conditions for full injection process, including the opening and closing of the injector. An injection time of 6 ms, velocity of 0.33 mm/ms and a lift of 0.5 mm were selected for opening and closing of injector based on experimental test. The simulation shows that the volume inside the injector is a kind of fuel accumulator, and the opening process of the needle influence the flow parameters in an inlet cross-section after a certain time, depending on a channel cross section. The calculations allowed to select the ratio of an injector duct cross sectional area to the aperture area of the injection capable of the reducing pressure loss. The unusual location of the injector in the socket of a glow plug in the Andoria ADCR engine makes a stream be impaired by a part of the head. This research result would be useful in developing an injector construction which will be used for an investigation of CNG addition into diesel engine.


    Directory of Open Access Journals (Sweden)



    Full Text Available Existing diesel engines are under stringent emission regulation particularly of smoke and particulate matter in their exhaust. Compressed Natural Gas and Diesel dual fuel operation is regarded as one of the best ways to control emissions from diesel engines and simultaneously saving petroleum based diesel fuel. Dual fuel engineis a conventional diesel engine which burn either gaseous fuel or diesel or both at the same time. In the present paper an experimental research was carried out on a laboratory single cylinder, four-stroke variable compression ratio, direct injection diesel engine converted to CNG-Diesel dual fuel mode to analyze the performance and emission characteristics of pure diesel first and then CNG-Diesel dual fuel mode. The measurements were recorded for the compression ratio of 15 and 17.5 at CNG substitution rates of 30% and 60% and varying theload from idle to rated load of 3.5kW in steps of 1 up to 3kW and then to 3.5kW. The results reveal that brake thermal efficiency of dual fuel engine is in the range of 30%-40% at the rated load of 3.5 kW which is 11%-13% higher than pure diesel engine for 30% and 60% CNG substitution rates. This trend is observed irrespective of the compression ratio of the engine. Brake specific fuel consumption of dual fuel engine is found better than pure diesel engine at all engine loads and for both CNG substitution rates. It is found that there is drastic reduction in CO, CO2, HC, NOx and smoke emissions in the exhaust of dual fuel engine at all loads and for 30% and 60% CNG substitution rates by employing some optimum operating conditions set forth for experimental investigations in this study.

  12. [Case of continuous trans-arterial calcium gluconate infusion using a direct arterial sphygmomanometry line that exhibited dramatic improvement of chemical burns on the fingers caused by hydrofluoric acid]. (United States)

    Miyamoto, Kazuyuki; Shimizu, Makiko; Tanaka, Kotaro; Minemura, Atsuko; Tamatsukuri, Tatsuro; Miyake, Yasufumi; Aruga, Tohru


    Hydrofluoric acid (HFA) is commonly used and many injuries occur on the upper extremities following exposure to HFA. The use of calcium gluconate (CG) -containing gel or local injections of CG are widely used for the initial treatment of HFA exposure. However, severe pain continues in some cases despite the treatment. There was a report that trans-arterial CG infusion could improve HFA burns, however, such treatment is not an established clinical procedure. A 30-year-old male presented at our hospital with severe pain in his left thumb. He had been cleaning tiles with an HFA-containing detergent. We diagnosed him with a chemical burn due to HFA exposure. Local CG injections were tried several times, but his terrible pain continued. Therefore, a direct arterial sphygmomanometry line was inserted from the left radial artery, and continuous transarterial CG injection was performed. His terrible pain dramatically improved. Direct arterial sphygmomanometry systems are widely used in the critical care field to monitor the hemodynamics and ICU staffs are used to dealing with it. Moreover, continuous saline infusion prevents the tube obstruction. Continuous CG infusion from a direct arterial sphygmomanometry line is simple and safe way to administer CG in HFA burns.

  13. Effect of ignition timing and hydrogen fraction on combustion and emission characteristics of natural gas direct-injection engine

    Institute of Scientific and Technical Information of China (English)


    An experimental study on the combustion and emission characteristics of a direct-injection spark-ignited engine fueled with natural gas/hydrogen blends under various ignition timings was conducted.The results show that ignition timing has a significant influence on engine performance,combustion and emissions.The interval between the end of fuel injection and ignition timing is a very important parameter for direct-injection natural gas engines.The turbulent flow in the combustion chamber generated by the fuel jet remains high and relative strong mixture stratification is introduced when decreasing the angle interval between the end of fuel injection and ignition timing giving fast burning rates and high thermal efficiencies.The maximum cylinder gas pressure,maximum mean gas temperature,maximum rate of pressure rise and maximum heat release rate increase with the advancing of ignition timing.However,these parameters do not vary much with hydrogen addition under specific ignition timing indicating that a small hydrogen fraction addition of less than 20% in the present experiment has little influence on combustion parameters under specific ignition timing.The exhaust HC emission decreases while the exhaust CO2 concentration increases with the advancing of ignition timing.In the lean combustion condition,the exhaust CO does not vary much with ignition timing.At the same ignition timing,the exhaust HC decreases with hydrogen addition while the exhaust CO and CO2 do not vary much with hydrogen addition.The exhaust NOx increases with the advancing of' ignition timing and the behavior tends to be more obvious at large ignition advance angle.The brake mean effective pressure and the effective thermal efficiency of natural gas/hydrogen mixture combustion increase compared with those of natural gas combustion when the hydrogen fraction is over 10%.

  14. The Effect of Injection Timings on Performance and Emissions of Compressed Natural-Gas Direct Injection Engine

    Directory of Open Access Journals (Sweden)

    Saad Aljamali


    Full Text Available This experimental part investigates the effect of injection timing on performance and emissions of homogenous mixture compressed natural-gas direct injection. The engine of 1.6 L capacity, 4 cylinders, spark ignition, and compression ratio of 14 was used. Performance and emission were recorded under wide-open throttle using an engine control system (Rotronics and the portable exhaust gas analyser (Kane. The engine was tested at speed ranging from 1500 revolutions per minute (RPM to 4000 RPM with 500 RPM increments. The engine control unit (ECU was modified using Motec 800. The injection timings investigated were at the end of injection (EOI 120 bTDC, 180 bTDC, 300 bTDC, and 360 bTDC. Results show high brake power, torque, and BMEP with 120 as compared with the other injection timings. At 4000 RPM the power, torque, and BMEP with 120 were 5% compared to that with 180. Furthermore, it shows low BSFC and high fuel conversion efficiency with 120. With 360, the engine produced less CO and CO2 at higher speeds.

  15. Uncooled EGR as a means of limiting wall-wetting under early direct injection conditions

    NARCIS (Netherlands)

    Boot, M.D.; Luijten, C.C.M.; Somers, L.M.T.; Eguz, U.; Erp, D.D.T.M. van; Albrecht, A.; Baert, R.S.G.


    Collision of injected fuel spray against the cylinder liner (wall-wetting) is one of the main hurdles that must be overcome in order for early direct injection Premixed Charge Compression Ignition (EDI PCCI) combustion to become a viable alternative for conventional DI diesel combustion. Preferably,

  16. Safety and efficacy of excision and direct closure in acute burns surgery: outcome analysis in a prospective series of 100 patients and a survey of UK burns surgeons' attitudes. (United States)

    Bain, Charles J; Wang, Tim; McArthur, Gordon; Williams, Greg; Atkins, Joanne; Jones, Isabel


    Many burns surgeons avoid excision and direct closure of acute burns owing to concerns over wound dehiscence, scarring and infection. There is no evidence in the literature to support this practice. We present outcomes of a prospective series of 100 patients who underwent excision and direct closure of 138 burns over a 2-year period, along with results from a survey sent to 33 senior burns surgeons to gauge attitudes towards direct closure in burns surgery. 47% of survey respondents never perform direct closure. Dehiscence was cited as the most common concern, followed by hypertrophic scarring (HTS). In our cohort, the superficial dehiscence rate was 12% and the HTS rate was 16%, with no scarring contractures. Patients with healing time greater than 14 days were more likely to develop HTS (p=0.008), as were those with wound dehiscence (p=0.014). Patients undergoing part-grafting in addition to direct closure took significantly longer to heal than those undergoing direct closure alone (p=0.0002), with the donor site or graft delaying healing in the majority. Excision and direct closure of acute burn wounds avoids donor site morbidity and has an acceptable complication rate. It is a safe and effective treatment for full thickness burns in selected cases.

  17. Multi-Element Lean Direct Injection Combustor Single Element Demonstration Project (United States)

    National Aeronautics and Space Administration — We propose to demonstrate the feasibility in a single element of a Multi-Element Lean Direct Injection, ME-LDI, Combustion concept. The concept will have the...

  18. Production of horse foals via direct injection of roscovitine-treated donor cells and activation by injection of sperm extract. (United States)

    Hinrichs, K; Choi, Y H; Love, C C; Chung, Y G; Varner, D D


    We evaluated the effects of different donor cell treatments and activation methods on production of blastocysts after equine nuclear transfer. Nuclear transfer was performed by direct injection of donor cells, using a piezo drill, and standard activation was by injection of sperm factor followed by culture with 6-dimethylaminopurine. There was no difference in blastocyst development between embryos produced with roscovitine-treated or confluent donor cells (3.6% for either treatment). Addition of injection of roscovitine or culture with cycloheximide at the time of activation did not affect blastocyst development. Overall, transfer of eight blastocysts produced using roscovitine-treated donor cells and our standard activation protocol yielded three pregnancies, of which two (25% of transferred embryos) resulted in delivery of viable foals. Flow cytometric evaluation showed that roscovitine treatment significantly increased the proportion of cells classified as small, in comparison to growth to confluence or serum deprivation, but did not significantly affect the proportion of cells in G0/G1 (2N DNA content). Transfer of one blastocyst produced using roscovitine-treated donor cells, with addition of roscovitine injection at activation, yielded one pregnancy which was lost before 114 days' gestation. Transfer to recipients of two blastocysts produced using confluent donor cells with addition of cycloheximide at activation gave no resulting pregnancies. We conclude that roscovitine treatment of donor cells yields equivalent blastocyst production after nuclear transfer to that for confluent donor cells, and that direct injection of roscovitine-treated donor cells, followed by activation using sperm extract, is compatible with efficient production of viable cloned foals.

  19. Direct and indirect responses of tallgrass prairie butterflies to prescribed burning (United States)

    Vogel, Jennifer A.; Koford, Rolf R.; Debinski, Diane M.


    Fire is an important tool in the conservation and restoration of tallgrass prairie ecosystems. We investigated how both the vegetation composition and butterfly community of tallgrass prairie remnants changed in relation to the elapsed time (in months) since prescribed fire. Butterfly richness and butterfly abundance were positively correlated with the time since burn. Habitat-specialist butterfly richness recovery time was greater than 70 months post-fire and habitat-specialist butterfly abundance recovery time was approximately 50 months post-fire. Thus, recovery times for butterfly populations after prescribed fires in our study were potentially longer than those previously reported. We used Path Analysis to evaluate the relative contributions of the direct effect of time since fire and the indirect effects of time since fire through changes in vegetation composition on butterfly abundance. Path models highlighted the importance of the indirect effects of fire on habitat features, such as increases in the cover of bare ground. Because fire return intervals on managed prairie remnants are often less than 5 years, information on recovery times for habitat-specialist insect species are of great importance. ?? 2010 Springer Science+Business Media B.V.

  20. An evaluation of Emergency Management of Severe Burn (EMSB) course in Bangladesh: a strategic direction. (United States)

    Biswas, Animesh; Rahman, Fazlur; Maitz, Peter; Baset, Kamran Ul; Hossain, Jahangir; Mashreky, Saidur Rahman


    Burn is one of the major public health problems in Bangladesh. Specialized personnel and technologies are required, however, in many cases they are not readily available. Taking the situation into account, Interplast Australia and New Zealand, Australia & New Zealand Burn Association (ANZBA), and Centre for Injury Prevention and Research, Bangladesh (CIPRB) initiated Emergency Management of Severe Burn (EMSB) training programme for Bangladeshi physicians in 2008 to help improving their burn management skill. The study was designed to evaluate the effect of EMSB programme in Bangladesh. Both qualitative and quantitative methods were adopted. A cross-sectional survey was conducted to obtain quantitative information from 38 randomly selected EMSB-trained doctors among 380 trained physicians based on a five year database of EMSB (2008-2012). In-depth interviews (IDIs) and focus group discussion (FGD) were used as data collection techniques to get information. A total of 32 participants completed the interview. It was found that 87.5% (n=28) doctors were using their skill in burn management that they learnt from the EMSB course. About 43.8% (n=14) doctors felt that the course largely helped improve their confidence. Majority (56.2%, n=18) of doctors stated EMSB is essential for the Bangladeshi doctors to learn better management of burns. Qualitative findings show that the courses were organized successfully with an excellent coordination, maintaining same quality and standard as running anywhere in the world. For its effectiveness, the course has been recommended to train graduate nurses and junior doctors from the periphery of the country. EMSB has already created a large doctor community who are able to effectively manage burn patients. It also has proven its indispensability for learning burn management skill. The EMSB established a platform to serve the burn victims and reduce the burden of injuries in Bangladesh.

  1. Combustion characteristics of a direct-injection diesel engine fueled with Fischer-Tropsch diesel

    Institute of Scientific and Technical Information of China (English)

    HUANG Yongcheng; ZHOU Longbao; PAN Keyu


    Fischer-Tropsch (F-T) diesel fuel is characterized by a high cetane number, a near-zero sulphur content and a very low aromatic level. On the basis of the recorded incylinder pressures and injector needle lifts, the combustion characteristics of an unmodified single-cylinder directinjection diesel engine operating on F-T diesel fuel are analyzed and compared with those of conventional diesel fuel operation. The results show that F-T diesel fuel exhibits a slightly longer injection delay and injection duration, an average of 18.7% shorter ignition delay, and a comparable total combustion duration when compared to those of conventional diesel fuel. Meanwhile, F-T diesel fuel displays an average of 26.8% lower peak value of premixed burning rate and a higher peak value of diffusive burning rate. In addition, the F-T diesel engine has a slightly lower peak combustion pressure, a far lower rate of pressure rise, and a lower mechanical load and combustion noise than the conventional diesel engine. The brake specific fuel consumption is lower and the effective thermal efficiency is higher for F-T diesel fuel operation.

  2. New clinical guidelines for selective direct injection therapy of the parathyroid glands in chronic dialysis patients. (United States)

    Onoda, Noritaka; Fukagawa, Masafumi; Tominaga, Yoshihiro; Kitaoka, Masafumi; Akizawa, Tadao; Koiwa, Fumihiko; Kakuta, Takatoshi; Kurokawa, Kiyoshi


    In 2000, the Japanese Society for Parathyroid Intervention issued the 'Guidelines for percutaneous ethanol injection therapy of the parathyroid glands in chronic dialysis patients'. Since then, the concept of 'selective PEIT' has been well accepted and the number of patients treated by this method in Japan has increased. Recently, it has been reported that the effect of PEIT differs depending on the degree of nodular hyperplasia. Several new drugs have become available since 2000, and active vitamin D and its analogue have also been used for direct injection into the parathyroids. We present the new 'Guidelines for selective direct injection therapy of the parathyroid glands in chronic dialysis patients', a revised version of the 2000 Guidelines. We believe that these new guidelines are useful for selecting direct injection therapy in patients with advanced secondary hyperparathyroidism.

  3. Direct radiative effect of carbonaceous aerosols from crop residue burning during the summer harvest season in East China (United States)

    Yao, Huan; Song, Yu; Liu, Mingxu; Archer-Nicholls, Scott; Lowe, Douglas; McFiggans, Gordon; Xu, Tingting; Du, Pin; Li, Jianfeng; Wu, Yusheng; Hu, Min; Zhao, Chun; Zhu, Tong


    East China experiences extensive crop residue burnings in fields during harvest season. The direct radiative effect (DRE) of carbonaceous aerosols from crop residue burning in June 2013 in East China was investigated using the Weather Research and Forecasting Model coupled with Chemistry (WRF-Chem). Absorption of organic aerosol (OA) in the presence of brown carbon was considered using the parameterization of Saleh et al. (2014), in which the imaginary part of the OA refractive index is a function of wavelength and the ratio of black carbon (BC) and OA. The carbonaceous emissions from crop fires were estimated using the Moderate Resolution Imaging Spectroradiometer (MODIS) fire radiative power (FRP) product with a localized crop-burning-sourced BC-to-organic carbon (OC) ratio emission ratio of 0.27. Evaluation of the model results with in situ measurements of particulate matter with aerodynamic diameter less than 2.5 µm (PM2. 5) chemical composition, MODIS aerosol optical depth (AOD) detections and meteorological observations showed that this model was able to reproduce the magnitude, spatial variation and optical characteristics of carbonaceous aerosol pollution. The observed BC and OC peak concentrations at the site in Suixi, Anhui province, during the 2013 wheat burning season reached 55.3 µg m-3 and 157.9 µg m-3. WRF-Chem simulations reproduced these trends with a correlation coefficient of 0.74, estimating that crop residue burning contributed 86 and 90 % of peak BC and OC, respectively. The simulated hourly DRE from crop residue burning at the top of atmosphere (TOA) reached a maximum of +22.66 W m-2 at the Suixi site. On average, the simulations showed that the crop residue burning introduced a net positive DRE of +0.14 W m-2 at TOA throughout East China, with BC from this source as the main heating contributor (+0.79 W m-2). The OA DRE from crop burning (-0.22 W m-2) was a combined effect of the positive DRE of absorption (+0.21 W m-2) and a stronger

  4. Direct subcutaneous injection of polyethylene particles over the murine calvaria results in dramatic osteolysis. (United States)

    Rao, Allison J; Zwingenberger, Stefan; Valladares, Roberto; Li, Chenguang; Lane Smith, Robert; Goodman, Stuart B; Nich, Christophe


    The murine calvarial model has been widely employed for the in vivo study of particle-induced osteolysis, the most frequent cause of aseptic loosening of total joint replacements. Classically, this model uses an open surgical technique in which polyethylene (PE) particles are directly spread over the calvarium for the induction of osteolysis. We evaluated a minimally invasive modification of the calvarial model by using a direct subcutaneous injection of PE particles. Polyethylene (PE) particles were injected subcutaneously over the calvaria of C57BL6J ten-week-old mice ("injection" group) or were implanted after surgical exposure of the calvaria ("open" group) (n = 5/group). For each group, five additional mice received no particles and served as controls. Particle-induced osteolysis was evaluated two weeks after the procedure using high-definition microCT imaging. Polyethylene particle injection over the calvaria resulted in a 40% ± 1.8% decrease in the bone volume fraction (BVF), compared to controls. Using the "open surgical technique", the BVF decreased by 16% ± 3.8% as compared to controls (p subcutaneous injection of PE particles over the murine calvaria produced more profound resorption of bone. Polyethylene particle implantation by injection is less invasive and reliably induces osteolysis to a greater degree than the open technique. This subcutaneous injection method will prove useful for repetitive injections of particles, and the assessment of potential local or systemic therapies.

  5. The direct effects of strain on burning rates of composite solid propellants (United States)

    Langhenry, M. T.


    A mathematical model is developed to predict burn rate augmentation due to strain in a composite solid propellant. The model assumes the effect is due to the ability of the flame to penetrate the small fissures and voids that form when a propellant is strained. The number and size of these fissures is obtained by applying a flaw propagation analysis to randomly distributed flaws that form when the binder-oxidizer particle bonds break under stress. A flame height is calculated with Summerfield's burn rate equation and is used to compute the burn rate augmentation based upon the additional burn area created when the flame penetrates the fissures. Comparisons are made with data obtained from published sources. The existence of threshold pressure and strains, above which augmentation occurs, is verified although the model predicts a lower threshold pressure and higher threshold strain than expected. Further results and applications of the model are discussed.

  6. Influence of injection pressures till to 1,000 bar on the carburetion in a spark ignition engine with direct injection; Einfluss von Einspritzdruecken bis 1000 bar auf die Gemischbildung in einem Ottomotor mit Direkteinspritzung

    Energy Technology Data Exchange (ETDEWEB)

    Buri, Stefan; Schumann, Florian; Kubach, Heiko; Spicher, Ulrich [Karlsruher Institut fuer Technologie (KIT) (DE). Inst. fuer Kolbenmaschinen (IFKM); Kneifel, Alexander [MTU Friedrichshafen GmbH (Germany)


    This paper presents the results of optical investigations of the impact of injection pressures of up to 1000 bar on mixture formation in a spray-guided direct injection engine. The maximum load in stratified operation of an engine with such a spray-guided combustion system is limited by the achievable quality of the mixture. In particular, when using multi hole injectors, the limit of stratified operation is reached rather early, due to comparatively low flow rates and thus insufficient stratification. One measure to increase the flow rate is to increase the injection pressure. The goal of this measure is to generate a more compact stratification, leading to combustion at richer air fuel ratios. This enables reductions of burning duration, hydrocarbon- and particulate emissions. The fundamental impact of increasing the injection pressure from 200 up to 1000 bar on mixture formation was investigated by using LIF- and Mie-scattering in a pressure chamber. Following that, the mixture formation was investigated under real conditions in a single cylinder engine by visualizing the injection process using Mie-scattering. Finally the results of engine operation are compared with those from the pressure chamber. (orig.)

  7. Computer animation of the stratified mixture shape in gasoline direct injection engine

    Energy Technology Data Exchange (ETDEWEB)

    Sendyka, B.; Pisarczyk, W.; Pajak, M. [Cracow University of Technology (Poland); Lindberg, W. [University of Wyoming (United States)


    The present method of direct fuel injection in Gasoline Direct Injection Engines (GDIE) creates a conical fuel stream, which is inefficient for GDIE. In this paper we analyzed how to achieve stratified conical shape of the rich fuel mixture. The kernel of the rich mixture should be located between the electrodes of the spark plug. This is achieved when the conical stream is bounced back from the surface of the bowl of the piston. The computer animation of the trajectory of the convergent fuel stream was based on equations of the parameters for fuel stream, injection pressure and angle of fuel injector. The presented animation allows us to determine the movement of the stream, from the beginning of injection to the electrodes of the spark plug, where the combustion process of the rich mixture kernel starts. (author)

  8. Method for operating a spark-ignition, direct-injection internal combustion engine

    Energy Technology Data Exchange (ETDEWEB)

    Narayanaswamy, Kushal; Koch, Calvin K.; Najt, Paul M.; Szekely, Jr., Gerald A.; Toner, Joel G.


    A spark-ignition, direct-injection internal combustion engine is coupled to an exhaust aftertreatment system including a three-way catalytic converter upstream of an NH3-SCR catalyst. A method for operating the engine includes operating the engine in a fuel cutoff mode and coincidentally executing a second fuel injection control scheme upon detecting an engine load that permits operation in the fuel cutoff mode.

  9. Numerical modeling of a Jet Ignition Direct Injection (JIDI) LPG engine


    albert boretti


    The paper presents indirectly validated simulations of the operation of a LPG engine fitted with Direct Injection (DI) and Jet Ignition (JI). It is demonstrated that the engine may have diesel like efficiencies and load control by quantity of fuel injected.  As the liquid propane quickly evaporates after injection in the main chamber, the main chamber mixture may be much closer to stoichiometry than a diesel for a better specific power at low engine speeds. This design also works at the high ...

  10. Numerical investigation of natural gas direct injection properties and mixture formation in a spark ignition engine

    Directory of Open Access Journals (Sweden)

    Yadollahi Bijan


    Full Text Available In this study, a numerical model has been developed in AVL FIRE software to perform investigation of Direct Natural Gas Injection into the cylinder of Spark Ignition Internal Combustion Engines. In this regard two main parts have been taken into consideration, aiming to convert an MPFI gasoline engine to direct injection NG engine. In the first part of study multi-dimensional numerical simulation of transient injection process, mixing and flow field have been performed via three different validation cases in order to assure the numerical model validity of results. Adaption of such a modeling was found to be a challenging task because of required computational effort and numerical instabilities. In all cases present results were found to have excellent agreement with experimental and numerical results from literature. In the second part, using the moving mesh capability the validated model has been applied to methane Injection into the cylinder of a Direct Injection engine. Five different piston head shapes along with two injector types have been taken into consideration in investigations. A centrally mounted injector location has been adapted to all cases. The effects of injection parameters, combustion chamber geometry, injector type and engine RPM have been studied on mixing of air-fuel inside cylinder. Based on the results, suitable geometrical configuration for a NG DI Engine has been discussed.

  11. Direct fuel injection in spark ignition engines; Injecao direta de combustivel em motores de ignicao por centelha

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Rodrigo Fernando Estella dos; Hildebrand Junior, Leonidas; Passarini, Luis Carlos; Santos, Antonio Moreira dos; Bezerra, Adriano Carlos Nogueira [Sao Paulo Univ., Sao Carlos, SP (Brazil). Dept. de Engenharia Mecanica]. E-mail:


    This paper presents the state-of-art of the fuel direct electronic injection, specifically the Otto cycle, the present technology for feasibility of the utilization, the characteristics of the engine using this system, by comparison with systems using the indirect fuel injection, the obtained results with laboratory experiments performed in direct and indirect fuel injection and conclusions as well.

  12. Development of High Efficiency and Low Emission Low Temperature Combustion Diesel Engine with Direct EGR Injection (United States)

    Ho, R. J.; Kumaran, P.; Yusoff, M. Z.


    Focus on energy and environmental sustainability policy has put automotive research & development directed to developing high efficiency and low pollutant power train. Diffused flame controlled diesel combustion has reach its limitation and has driven R&D to explore other modes of combustions. Known effective mode of combustion to reduce emission are Low temperature combustion (LTC) and homogeneous charge combustion ignition by suppressing Nitrogen Oxide(NOx) and Particulate Matter (PM) formation. The key control to meet this requirement are chemical composition and distribution of fuel and gas during a combustion process. Most research to accomplish this goal is done by manipulating injected mass flow rate and varying indirect EGR through intake manifold. This research paper shows viable alternative direct combustion control via co-axial direct EGR injection with fuel injection process. A simulation study with OpenFOAM is conducted by varying EGR injection velocity and direct EGR injector diameter performed with under two conditions with non-combustion and combustion. n-heptane (C7H16) is used as surrogate fuel together with 57 species 290 semi-detailed chemical kinetic model developed by Chalmers University is used for combustion simulation. Simulation result indicates viability of co-axial EGR injection as a method for low temperature combustion control.

  13. Direct in vivo injection of ~(131)I-GMS and its distribution and excretion in rabbit

    Institute of Scientific and Technical Information of China (English)


    AIM: To explore the distribution and metabolism of 131 I-gelatin microspheres ( 131 I-GMSs) in rabbits after direct injection into rabbits’ livers.METHODS: Twenty-eight healthy New Zealand rabbits were divided into seven groups,with four rabbits per group.Each rabbit’s hepatic lobes were directly injected with 41.336 ± 5.106 MBq 131 I-GMSs.Each day after 131 I-GMSs administration,4 rabbits were randomly selected,and 250 μL of serum was collected for γ count.Hepatic and thyroid functions were tested on days ...

  14. Spray and combustion visualization of bio-diesel in a direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Pan Jianfeng


    Full Text Available By using the self-developed dynamic visualization photographic setup, this article investigated some major factors affecting the spray and combustion process of diesel engine fueled by biodiesel. The experimental results show: With the increase of biodiesel percentage, fuel injection advances slightly, the ignition delay becomes shorter and the duration of combustion lengthens. Engine speed has little effect on the spray. However, the combustion rate is increased and the burning time becomes shorter with the increase of engine speed, although the duration of combustion in terms of crank angle increases. With the increase of needle opening pressure, both the spray cone angle and the spray penetration of biodiesel increases, the atomization of spray improves, the ignition delay and the duration of combustion becomes shorter, the peak pressure increases.

  15. Numerical modeling of a Jet Ignition Direct Injection (JIDI LPG engine

    Directory of Open Access Journals (Sweden)

    albert boretti


    Full Text Available The paper presents indirectly validated simulations of the operation of a LPG engine fitted with Direct Injection (DI and Jet Ignition (JI. It is demonstrated that the engine may have diesel like efficiencies and load control by quantity of fuel injected.  As the liquid propane quickly evaporates after injection in the main chamber, the main chamber mixture may be much closer to stoichiometry than a diesel for a better specific power at low engine speeds. This design also works at the high engine speeds impossible for the diesel, as combustion within the main chamber is controlled by the turbulent mixing rather than the vaporization and diffusion processes of the injected fuel of the diesel. 

  16. Optical characterization of continental and biomass-burning aerosols over Bozeman, Montana: A case study of the aerosol direct effect (United States)

    Nehrir, Amin R.; Repasky, Kevin S.; Reagan, John A.; Carlsten, John L.


    Atmospheric aerosol optical properties were observed from 21 to 27 September 2009 over Bozeman, Montana, during a transitional period in which background polluted rural continental aerosols and well-aged biomass-burning aerosols were the dominant aerosol types of extremely fresh biomass-burning aerosols resulting from forest fires burning in the northwestern United States and Canada. Aerosol optical properties and relative humidity profiles were retrieved using an eye-safe micropulse water vapor differential absorption lidar (DIAL) (MP-DIAL), a single-channel backscatter lidar, a CIMEL solar radiometer as part of the Aerosol Robotic Network (AERONET), a ground-based integrating nephelometer, and aerosol products from Moderate Resolution Imaging Spectroradiometer (MODIS) Terra and Aqua. Aerosol optical depths (AODs) measured during the case study ranged between 0.03 and 0.17 (0.015 and 0.075) at 532 nm (830 nm) as episodic combinations of fresh and aged biomass-burning aerosols dominated the optical depth of the pristinely clean background air. Here, a pristinely clean background refers to very low AOD conditions, not that the aerosol scattering and absorption properties are necessarily representative of a clean aerosol type. Diurnal variability in the aerosol extinction to backscatter ratio (Sa) of the background atmosphere derived from the two lidars, which ranged between 55 and 95 sr (50 and 90 sr) at 532 nm (830 nm), showed good agreement with retrievals from AERONET sun and sky measurements over the same time period but were consistently higher than some aerosol models had predicted. Sa measured during the episodic smoke events ranged on average from 60 to 80 sr (50 to 70 sr) at 532 nm (830 nm) while the very fresh biomass-burning aerosols were shown to exhibit significantly lower Sa ranging between 20 and 40 sr. The shortwave direct radiative forcing that was due to the intrusion of biomass-burning aerosols was calculated to be on average -10 W/m2 and was

  17. Revisiting ocean carbon sequestration by direct injection: a global carbon budget perspective (United States)

    Reith, Fabian; Keller, David P.; Oschlies, Andreas


    In this study we look beyond the previously studied effects of oceanic CO2 injections on atmospheric and oceanic reservoirs and also account for carbon cycle and climate feedbacks between the atmosphere and the terrestrial biosphere. Considering these additional feedbacks is important since backfluxes from the terrestrial biosphere to the atmosphere in response to reducing atmospheric CO2 can further offset the targeted reduction. To quantify these dynamics we use an Earth system model of intermediate complexity to simulate direct injection of CO2 into the deep ocean as a means of emissions mitigation during a high CO2 emission scenario. In three sets of experiments with different injection depths, we simulate a 100-year injection period of a total of 70 GtC and follow global carbon cycle dynamics over another 900 years. In additional parameter perturbation runs, we varied the default terrestrial photosynthesis CO2 fertilization parameterization by ±50 % in order to test the sensitivity of this uncertain carbon cycle feedback to the targeted atmospheric carbon reduction through direct CO2 injections. Simulated seawater chemistry changes and marine carbon storage effectiveness are similar to previous studies. As expected, by the end of the injection period avoided emissions fall short of the targeted 70 GtC by 16-30 % as a result of carbon cycle feedbacks and backfluxes in both land and ocean reservoirs. The target emissions reduction in the parameter perturbation simulations is about 0.2 and 2 % more at the end of the injection period and about 9 % less to 1 % more at the end of the simulations when compared to the unperturbed injection runs. An unexpected feature is the effect of the model's internal variability of deep-water formation in the Southern Ocean, which, in some model runs, causes additional oceanic carbon uptake after injection termination relative to a control run without injection and therefore with slightly different atmospheric CO2 and

  18. Push-through direct injection NMR: an optimized automation method applied to metabolomics (United States)

    There is a pressing need to increase the throughput of NMR analysis in fields such as metabolomics and drug discovery. Direct injection (DI) NMR automation is recognized to have the potential to meet this need due to its suitability for integration with the 96-well plate format. ...

  19. 78 FR 70240 - Airworthiness Directives; Lycoming Engines, Fuel Injected Reciprocating Engines (United States)


    ..., Amendment 39-16894 (76 FR 79051, December 21, 2011), (``AD 2011-26-04''), for certain Lycoming Engines fuel...-16894 (76 FR 79051, December 21, 2011). (c) Applicability This AD applies to Lycoming Engines fuel... Directives; Lycoming Engines, Fuel Injected Reciprocating Engines AGENCY: Federal Aviation...

  20. Direct and semi-direct impacts of absorbing biomass burning aerosol on the climate of southern Africa: a Geophysical Fluid Dynamics Laboratory GCM sensitivity study

    Directory of Open Access Journals (Sweden)

    C. A. Randles


    Full Text Available Tropospheric aerosols emitted from biomass burning reduce solar radiation at the surface and locally heat the atmosphere. Equilibrium simulations using an atmospheric general circulation model (GFDL AGCM indicate that strong atmospheric absorption from these particles can cool the surface and increase upward motion and low-level convergence over southern Africa during the dry season. These changes increase sea level pressure over land in the biomass burning region and spin-up the hydrologic cycle by increasing clouds, atmospheric water vapor, and, to a lesser extent, precipitation. Cloud increases serve to reinforce the surface radiative cooling tendency of the aerosol. Conversely, if the climate over southern Africa were hypothetically forced by high loadings of scattering aerosol, then the change in the low-level circulation and increased subsidence would serve to decrease clouds, precipitation, and atmospheric water vapor. Surface cooling associated with scattering-only aerosols is mitigated by warming from cloud decreases. The direct and semi-direct climate impacts of biomass burning aerosol over southern Africa are sensitive to the total amount of aerosol absorption and how clouds change in response to the aerosol-induced heating of the atmosphere.

  1. Effect of diesel-biodiesel-ethanol blend on combustion, performance, and emissions characteristics on a direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Jamrozik Arkadiusz


    Full Text Available The paper presents results of co-combustion of diesel-biodiesel-ethanol fuel blend in direct injection Diesel engine. Test was performed at constant rotational speed at three commonly used loads of this engine: 100%, 85%, and 70% of load. During the test hydrated ethanol was used at a concentration of 89% of alcohol. In this study, the ethanol fuel was added to diesel-biodiesel fuel blend with concentrations up to 50% with the increment of 5%. The biodiesel was used as an additive to pre-vent the stratification of ethanol and diesel blends. Thermodynamic parameters of engine were analyzed, and combustion process and exhaust emission were characterized. It turned out that with the increase in engine load is possible to utilize larger ethanol fraction in blend. With the increase of ethanol fuel in blend the in-crease in ignition delay (38.5% for full load was observed, but burning duration decreased (49% for full load. The ethanol fuel share in blend generally causes the increase in NOx emission (42% for full load due to higher oxygen content and higher in-cylinder temperatures. It turned out that, at full load the unrepeatability of indicated mean effective pressure was near the same up to 50% of ethanol fuel in blend (about 2%. In case of partial load at higher ethanol fuel fraction the in-crease in indicated mean effective pressure un-repeatability was observed.

  2. Spatial variability of the direct radiative forcing of biomass burning aerosols and the effects of land use change in Amazonia

    Directory of Open Access Journals (Sweden)

    E. T. Sena


    Full Text Available This paper addresses the Amazonian shortwave radiative budget over cloud-free conditions after considering three aspects of deforestation: (i the emission of aerosols from biomass burning due to forest fires; (ii changes in surface albedo after deforestation; and (iii modifications in the column water vapour amount over deforested areas. Simultaneous Clouds and the Earth's Radiant Energy System (CERES shortwave fluxes and aerosol optical depth (AOD retrievals from the Moderate Resolution Imaging SpectroRadiometer (MODIS were analysed during the peak of the biomass burning seasons (August and September from 2000 to 2009. A discrete-ordinate radiative transfer (DISORT code was used to extend instantaneous remote sensing radiative forcing assessments into 24-h averages.

    The mean direct radiative forcing of aerosols at the top of the atmosphere (TOA during the biomass burning season for the 10-yr studied period was −5.6 ± 1.7 W m−2. Furthermore, the spatial distribution of the direct radiative forcing of aerosols over Amazonia was obtained for the biomass burning season of each year. It was observed that for high AOD (larger than 1 at 550 nm the maximum daily direct aerosol radiative forcing at the TOA may be as high as −20 W m−2 locally. The surface reflectance plays a major role in the aerosol direct radiative effect. The study of the effects of biomass burning aerosols over different surface types shows that the direct radiative forcing is systematically more negative over forest than over savannah-like covered areas. Values of −15.7 ± 2.4 W m−2τ550 nm and −9.3 ± 1.7 W m−2τ550 nm were calculated for the mean daily aerosol forcing efficiencies over forest and savannah-like vegetation respectively. The overall mean annual land use change radiative forcing due to deforestation over the state of Rondônia, Brazil, was determined as −7.3 ± 0.9 W m

  3. Exploring a direct injection method for microfluidic generation of polymer microgels. (United States)

    Wang, Yihe; Tumarkin, Ethan; Velasco, Diego; Abolhasani, Milad; Lau, Willie; Kumacheva, Eugenia


    Microfluidics (MFs) offers a promising method for the preparation of polymer microgels with exquisite control over their dimensions, shapes and morphologies. A challenging task in this process is the generation of droplets (precursors for microgels) from highly viscous polymer solutions. Spatial separation of MF emulsification and gelation of the precursor droplets on chip can address this challenge. In the present work, we explored the application of the "direct injection" method for the preparation of microgels by adding a highly concentrated polymer solution or a gelling agent directly into the precursor droplets. In the first system, primary droplets were generated from a dilute aqueous solution of agarose, followed by the injection of the concentrated agarose solution directly in the primary droplets. The secondary droplets served as precursors for microgels. In the second system, primary droplets were generated from the low-viscous solution of methyl-β-cyclodextrin and poly(ethylene glycol) end-terminated with octadecyl hydrophobic groups. Addition of surfactant directly into the primary droplets led to the binding of methyl-β-cyclodextrin to the surfactant, thereby releasing hydrophobized poly(ethylene glycol) to form polymer microgels. Our results show that, when optimized, the direct injection method can be used for microgel preparation from highly viscous liquids and thus this method expands the range of polymers used for MF generation of microgels.

  4. Effects of thermoacoustic oscillations on spray combustion dynamics with implications for lean direct injection systems (United States)

    Chishty, Wajid Ali

    Thermoacoustic instabilities in modern high-performance, low-emission gas turbine engines are often observable as large amplitude pressure oscillations and can result in serious performance and structural degradations. These acoustic oscillations can cause oscillations in combustor through-flows and given the right phase conditions, can also drive unsteady heat release. To curb the potential harms caused by the existence of thermoacoustic instabilities, recent efforts have focused on the active suppression of these instabilities. Intuitively, development of effective active combustion control methodologies is strongly dependent on the knowledge of the onset and sustenance of thermoacoustic instabilities. Specially, non-premixed spray combustion environment pose additional challenges due to the inherent unstable dynamics of sprays. The understanding of the manner in which the combustor acoustics affect the spray characteristics, which in turn result in heat release oscillation, is therefore, of paramount importance. The experimental investigations and the modeling studies conducted towards achieving this knowledge have been presented in this dissertation. Experimental efforts comprise both reacting and non-reacting flow studies. Reacting flow experiments were conducted on a overall lean direct injection, swirl-stabilized combustor rig. The investigations spanned combustor characterization and stability mapping over the operating regime. The onset of thermoacoustic instability and the transition of the combustor to two unstable regimes were investigated via phase-locked chemiluminescence imaging and measurement and phase-locked acoustic characterization. It was found that the onset of the thermoacoustic instability is a function of the energy gain of the system, while the sustenance of instability is due to the in-phase relationship between combustor acoustics and unsteady heat release driven by acoustic oscillations. The presence of non-linearities in the system

  5. Tailpipe emissions from gasoline direct injection (GDI) and port fuel injection (PFI) vehicles at both low and high ambient temperatures. (United States)

    Zhu, Rencheng; Hu, Jingnan; Bao, Xiaofeng; He, Liqiang; Lai, Yitu; Zu, Lei; Li, Yufei; Su, Sheng


    Vehicle emissions are greatly influenced by various factors that are related to engine technology and driving conditions. Only the fuel injection method and ambient temperature are investigated in this research. Regulated gaseous and particulate matter (PM) emissions from two advanced gasoline-fueled vehicles, one with direct fuel injection (GDI) and the other with port fuel injection (PFI), are tested with conventional gasoline and ethanol-blended gasoline (E10) at both -7 °C and 30 °C. The total particle number (PN) concentrations and size distributions are monitored with an Electrical Low Pressure Impactor (ELPI(+)). The solid PN concentrations are measured with a condensation particle counter (CPC) after removing volatile matters through the particle measurement program (PMP) system. The results indicate that decreasing the ambient temperature from 30 °C to -7 °C significantly increases the fuel consumption and all measured emissions except for NOx. The GDI vehicle exhibits lower fuel consumption than the PFI vehicle but emits more total hydrocarbons (THC), PM mass and solid PN emissions at 30 °C. The adaptability of GDI technology appears to be better than that of PFI technology at low ambient temperature. For example, the CO, THC and PM mass emission factors of the PFI vehicle are higher than those of the GDI vehicle and the solid PN emission factors are comparable in the cold-start tests at -7 °C. Specifically, during start-up the particulate matter emissions of the PFI are much higher than the GDI. In most cases, the geometric mean diameter (GMD) of the accumulation mode particles is 58-86 nm for both vehicles, and the GMD of the nucleation mode particles is 10-20 nm. The results suggest that the gaseous and particulate emissions from the PFI vehicle should not be neglected compared to those from the GDI vehicle especially in a cold environment. Copyright © 2016 Elsevier Ltd. All rights reserved.


    Directory of Open Access Journals (Sweden)

    IONESCU Cozmin


    Full Text Available One solution for attaching soles on footwear is to inject them directly into the upper part using moulds with unique cavities. Injection moulds are manufactured for each sole design, for each foot, right and left, and for each size number. As a result of the market demand for a large number of soles designs, the execution costs of moulds for each of them are substantial. In the case of small manufacturers, injection moulds wear out morally long before they wear out physically. This paper will present some design solutions for moulds that have reusable parts that can be used from one sole design to another, without changing the entire mould. Using these moulds, soles design can be modified by interchanging some modules which are fitted into the main mould cavities. These solutions represent a cheaper and faster alternative for classic moulds, with unique single cavities.

  7. High-pressure liquid chromatography with direct injection of gas sample. (United States)

    Astanin, Anton I; Baram, Grigory I


    The conventional method of using liquid chromatography to determine the composition of a gaseous mixture entails dissolving vapors in a suitable solvent, then obtaining a chromatograph of the resulting solution. We studied the direct introduction of a gaseous sample into a C18 reversed-phase column, followed by separation of the components by HPLC with UV detection. Since the chromatography was performed at high pressure, vapors readily dissolved in the eluent and the substances separated in the column as effectively as in liquid samples. Samples were injected into the column in two ways: a) through the valve without a flow stop; b) after stopping the flow and relieving all pressure. We showed that an injectable gas volume could reach 70% of column dead volume. When an injected gaseous sample volume was less than 10% of the column dead volume, the resulting peaks were symmetrical and the column efficiency was high. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Research on Continuous Injection Direct Rolling Process for PMMA Optical Plate

    Directory of Open Access Journals (Sweden)

    HaiXiong Wang


    Full Text Available Continuous injection direct rolling (CIDR combined intermittent injection and rolling process is a new technology for molding optical polymer plates with microstructured patterns; research on forming PMMA optical plates is an aspect of it in this paper. The equipment of CIDR process consists of plastic injection module, precision rolling module, and automatic coiling module. Based on the establishing mathematical CIDR models, numerical analysis was used to explode the distribution of velocity, temperature, and pressure in injection-rolling zone. The simulation results show that it is feasible to control the temperature, velocity, and injection-rolling force, so it can form polymer plate under certain process condition. CIDR experiment equipment has been designed and produced. PMMA optical plate was obtained by CIDR experiments, longitudinal thickness difference is 0.005 mm/200 mm, horizontal thickness difference is 0.02/200 mm, transmittance is 86.3%, Haze is 0.61%, and the difference is little compared with optical glasses. So it can be confirmed that CIDR process is practical to produce PMMA optical plates.

  9. Mepolizumab Injection (United States)

    ... or do not go away: pain, redness, swelling, warmth, burning, or itching in the place mepolizumab was injected headache dry and itchy skin with or without red, scaly rashes back pain muscle spasms Some side ...

  10. Evolocumab Injection (United States)

    ... autoinjector in hot water, microwave, or place in sunlight.Before you use evolocumab injection, look at the ... chills pain or burning during urination muscle or back pain dizziness stomach pain Some side effects can be ...

  11. The influence of thermal regime on gasoline direct injection engine performance and emissions (United States)

    Leahu, C. I.; Tarulescu, S.


    This paper presents the experimental research regarding to the effects of a low thermal regime on fuel consumption and pollutant emissions from a gasoline direct injection (GDI) engine. During the experimental researches, the temperature of the coolant and oil used by the engine were modified 4 times (55, 65, 75 and 85 oC), monitoring the effects over the fuel consumption and emissions (CO2, CO and NOx). The variations in temperature of the coolant and oil have been achieved through AVL coolant and oil conditioning unit, integrated in the test bed. The obtained experimental results reveals the poor quality of exhaust gases and increases of fuel consumption for the gasoline direct injection engines that runs outside the optimal ranges for coolant and oil temperatures.

  12. Properties of Laser-Produced Highly Charged Heavy Ions for Direct Injection Scheme

    CERN Document Server

    Sakakibara, Kazuhiko; Hayashizaki, Noriyosu; Ito, Taku; Kashiwagi, Hirotsugu; Okamura, Masahiro


    To accelerate highly charged intense ion beam, we have developed the Direct Plasma Injection Scheme (DPIS) with laser ion source. In this scheme an ion beam from a laser ion source is injected directly to a RFQ linac without a low energy beam transport (LEBT) and the beam loss in the LEBT can be avoided. We achieved high current acceleration of carbon ions (60mA) by DPIS with the high current optimized RFQ. As the next setp we will use heavier elements like Ag, Pb, Al and Cu as target in LIS (using CO2, Nd-YAG or other laser) for DPIS and will examine properties of laser-produced plasma (the relationship of between charge state and laser power density, the current dependence of the distance from the target, etc).

  13. About the constructive and functional particularities of spark ignition engines with gasoline direct injection: experimental results (United States)

    Niculae, M.; Ivan, F.; Neacsu, D.


    The paper aims to analyze and compare the environmental performances between a gasoline direct engine and a multi-point injection engine. There are analyzed the stages of emission formation during the New European Driving Cycle. The paper points out the dynamic, economic and environmental performances of spark ignition engines equipped with a GDI systems. Reason why, we believe the widespread implementation of this technology is today an immediate need.

  14. NOx reduction by ozone injection and direct plasma treatment


    Stamate, Eugen; Salewski, Mirko


    NOx reduction by ozone injection and direct plasma treatment is investigated for different process parameters in a 6 m long serpentine reactor. Several aspects including the role of mixing scheme, water vapours, steep temperature gradient and time dependet NOx levels are taken into consideration. The process chemistry is monitored by FTIR, chemiluminiscence and absorbtion spectroscopy. The kinetic mechanism is also investigated in 3D simulations.

  15. Spontaneous pseudoaneurysm of the uterine artery during pregnancy treated by direct thrombin injection: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jung Hee; Kim, See Hyung; Kim, Young Hwan [Dept. Radiology, Keimyung University School of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of)


    Pseudoaneurysm of uterine artery during pregnancy is a very rare disease. It is mostly associated with uterine artery injury, usually occurring after proceeding conditions such as history of gynecologic operation and infection. However, the best treatment modality has not been established yet. Herein, we reported a case of spontaneous formation of uterine artery pseudoaneurysm during pregnancy treated by direct thrombin injection without any complication or recurrence.

  16. Feedback Direct Injection Current Readout For Infrared Charge-Coupled Devices (United States)

    Kubo, Kazuya; Wakayama, Hiroyuki; Kajihara, Nobuyuki; Awamoto, Kenji; Miyamoto, Yoshihiro


    We are proposing current readout for infrared charge coupled devices (IRCCDs) which can operate at higher temperatures. Feedback direct injection (FDI) consists of a simple amplifier of gain, AFDI was used in a medium-wavelength IRCCD operating at a high temperature. We made a 64-element HgCdTe linear IRCCD using FDI. The device operates at 195 K with an NETD of 0.5 K.

  17. Direct microcomputer controlled determination of zinc in human serum by flow injection atomic absorption spectrometry

    DEFF Research Database (Denmark)

    Simonsen, Kirsten Wiese; Nielsen, Bent; Jensen, Arne


    A procedure is described for the direct determination of zinc in human serum by fully automated, microcomputer controlled flow injection atomic absorption spectrometry (Fl-AAS). The Fl system is pumpless, using the negative pressure created by the nebuliser. It only consists of a three-way valve......, programmable from the microcomputer, to control the sample volume. No pre-treatment of the samples is necessary. The limit of detection is 0.14 mg l–1, and only small amounts of serum (

  18. Modelling of the wall jet in a direct injection diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Desantes, J.M.; Lapuerta, M.; Salavert, J.M. (Universidad Politecnica de Valencia (ES). Dept. Maquinas y Motores Termicos)


    As a part of a phenomenological model, a method for simulating the wall/jet interaction in a direct injection diesel engine is proposed. The method is based on the application of the momentum conservation equation in the different directions in which the wall jet is spread, and takes into account both the interaction with the combustion chamber geometry and with swirl. It takes as initial conditions the results of calculating the free jet, which is divided into packages. The predictions provide good agreement with those by other researchers. (author).

  19. A prospective evaluation of complications of 10,000 fluoroscopically directed epidural injections. (United States)

    Manchikanti, Laxmaiah; Malla, Yogesh; Wargo, Bradley W; Cash, Kimberly A; Pampati, Vidyasagar; Fellows, Bert


    Among the multiple modalities of treatments available in managing chronic spinal pain, including surgery and multiple interventional techniques, epidural injections by various routes, such as interlaminar epidural injections, caudal epidural injections, transforaminal epidural injections, and percutaneous adhesiolysis are common. Even though the complications of fluoroscopically directed epidural injections are fewer than blind epidural injections, and have better effectiveness, multiple complications have been reported in scattered case reports, with only minor complications in randomized or non-randomized studies and systematic reviews. Thus, prospective studies with large patient series are essential to determine the types and incidences of complications. A prospective, non-randomized study of patients undergoing interventional techniques from May 2008 to December 2009. A private interventional pain management practice, a specialty referral center in the United States. To assess the complication rate of fluoroscopically directed epidural injections. This study was carried out over a period of 20 months and included over 10,000 procedures: 39% caudal epidurals, 23% cervical interlaminar epidurals, 14% lumbar interlaminar epidurals, 13% lumbar transforaminal epidurals, 8% percutaneous adhesiolysis, and 3% thoracic interlaminar epidural procedures. All of the interventions were performed under fluoroscopic guidance in an ambulatory surgery center by one of 3 physicians. The complications encountered during the procedure and postoperatively were prospectively evaluated. Measurable outcomes employed were intravascular entry of the needle, profuse bleeding, local hematoma, bruising, dural puncture and headache, nerve root or spinal cord irritation with resultant injury, infectious complications, vasovagal reactions, and facial flushing. Intravascular entry was higher for adhesiolysis (11.6%) and lumbar transforaminal (7.9%) procedures compared to other epidurals which

  20. Weed control by direct injection of plant protection products according to specific situations

    Directory of Open Access Journals (Sweden)

    Krebs, Mathias


    Full Text Available Precision Farming in agriculture allows a site-specific management of the crop. The aim of plant protection is to apply plant protection products (PPP according to the site specific requirements on the field. Within the context of a research program to promote innovation, a sprayer with direct injection of plant protection products was developed. The direct injection offers site specific spraying of different individual PPP in a single pass. The sprayer prototype is equipped with a special spray boom combining three nozzle lines. In order to prevent delay times, the nozzle lines are preloaded before spraying. First results for weed control from test stand measurements and field trials showed that the injection pumps work with high accuracy. The prototype can be used without delay times site specific with up to three different herbicides. Field trials for site-specific weed control in winter wheat demonstrate the applicability of the system under practical conditions. By treatment of subareas herbicides and therefore costs could be saved. A reduction in yield compared with the conventionally treated field areas could not be ascertained. Also an efficacy reduction through washout of active ingredient from target surfaces due to simultaneous use of all three nozzle lines with up to 1050 l/ha application rate could not be detected. At high water spray rates, the efficacy effect occurs delayed. Overall, the newly developed direct injection system proved fieldabillity during the first tests. So weed control can be carried out situation-responsive, which can save herbicides and environmental impacts are reduced.

  1. Numerical investigation of CAI Combustion in the Opposed- Piston Engine with Direct and Indirect Water Injection (United States)

    Pyszczek, R.; Mazuro, P.; Teodorczyk, A.


    This paper is focused on the CAI combustion control in a turbocharged 2-stroke Opposed-Piston (OP) engine. The barrel type OP engine arrangement is of particular interest for the authors because of its robust design, high mechanical efficiency and relatively easy incorporation of a Variable Compression Ratio (VCR). The other advantage of such design is that combustion chamber is formed between two moving pistons - there is no additional cylinder head to be cooled which directly results in an increased thermal efficiency. Furthermore, engine operation in a Controlled Auto-Ignition (CAI) mode at high compression ratios (CR) raises a possibility of reaching even higher efficiencies and very low emissions. In order to control CAI combustion such measures as VCR and water injection were considered for indirect ignition timing control. Numerical simulations of the scavenging and combustion processes were performed with the 3D CFD multipurpose AVL Fire solver. Numerous cases were calculated with different engine compression ratios and different amounts of directly and indirectly injected water. The influence of the VCR and water injection on the ignition timing and engine performance was determined and their application in the real engine was discussed.

  2. Influence of narrow fuel spray angle and split injection strategies on combustion efficiency and engine performance in a common rail direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Raouf Mobasheri


    Full Text Available Direct injection diesel engines have been widely used in transportation and stationary power systems because of their inherent high thermal efficiency. On the other hand, emission regulations such as NOx and particulates have become more stringent from the standpoint of preserving the environment in recent years. In this study, previous results of multiple injection strategies have been further investigated to analyze the effects of narrow fuel spray angle on optimum multiple injection schemes in a heavy duty common rail direct injection diesel engine. An advanced computational fluid dynamics simulation has been carried out on a Caterpillar 3401 diesel engine for a conventional part load condition in 1600 r/min at two exhaust gas recirculation rates. A good agreement of calculated and measured in-cylinder pressure, heat release rate and pollutant formation trends was obtained under various operating points. Three different included spray angles have been studied in comparison with the traditional spray injection angle. The results show that spray targeting is very effective for controlling the in-cylinder mixture distributions especially when it accompanied with various injection strategies. It was found that the optimum engine performance for simultaneous reduction of soot and NOx emissions was achieved with 105° included spray angle along with an optimized split injection strategy. The results show, in this case, the fuel spray impinges at the edge of the piston bowl and a counterclockwise flow motion is generated that pushes mixture toward the center of the piston bowl.

  3. Effect of fuel injection rate and timing on the physical, chemical, and biological character of particulate emissions from a direct injection diesel

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, J.; Scholl, J.; Hibbler, F.; Bagley, S.; Leddy, D.; Abata, D.; Johnson, J.


    Formation of pollutants from diesel combustion and methods for their control have been reviewed. Of these methods, fuel injection rate and timing were selected for a parametric study relative to total particulate, soluble organic fraction (SOF), sulfates, solids and NO and NO/sub 2/ emissions from a heavy-duty, turbocharged, after-cooled, direct-injection (DI) diesel. Chemical analyses of the SOF were performed at selected engine conditions to determine the effects of injection rate and timing on each of the eight chemical subfractions comprising the SOF. Biological character of the SOF was determined using the Ames Salmonella/microsome bioassay. 54 refs.

  4. Characterization of Swirl-Venturi Lean Direct Injection Designs for Aviation Gas-Turbine Combustion (United States)

    Heath, Christopher M.


    Injector geometry, physical mixing, chemical processes, and engine cycle conditions together govern performance, operability and emission characteristics of aviation gas-turbine combustion systems. The present investigation explores swirl-venturi lean direct injection combustor fundamentals, characterizing the influence of key geometric injector parameters on reacting flow physics and emission production trends. In this computational study, a design space exploration was performed using a parameterized swirl-venturi lean direct injector model. From the parametric geometry, 20 three-element lean direct injection combustor sectors were produced and simulated using steady-state, Reynolds-averaged Navier-Stokes reacting computations. Species concentrations were solved directly using a reduced 18-step reaction mechanism for Jet-A. Turbulence closure was obtained using a nonlinear ?-e model. Results demonstrate sensitivities of the geometric perturbations on axially averaged flow field responses. Output variables include axial velocity, turbulent kinetic energy, static temperature, fuel patternation and minor species mass fractions. Significant trends have been reduced to surrogate model approximations, intended to guide future injector design trade studies and advance aviation gas-turbine combustion research.

  5. Redistribution of contaminants from pig slurry after direct injection into soil

    DEFF Research Database (Denmark)

    Amin, Mostofa; Bech, T B; Forslund, A;


    The redistribution of pig manure-borne contaminants after direct injection to soil was investigated in a field study. The spatial distribution of Escherichia coli, Salmonella Typhimurium Bacteriophage 28B and other slurry components in and around the injection slit was measured on day 0.15, 1, 6......, 18, and 46/49 at Silstrup (sandy clay loam) and Estrup (sandy loam), Denmark. Transport of the slurry components away from the slit was slower at Silstrup in comparison to Estrup, probably because of a higher slurry dry matter content and soil clay content. Slurry NH4-N dissipated and....../or was nitrified gradually at Silstrup and more rapidly at Estrup, but had disappeared completely at both sites within 49 days. The rate of disappearance of E. coli at Estrup was lower than at Silstrup. Survival of E. coli was high in the upper soil layer at both sites. The overall persistence of the bacteriophage...

  6. Direct drive target survival during injection in an inertial fusion energy power plant (United States)

    Petzoldt, R. W.; Goodin, D. T.; Nikroo, A.; Stephens, E.; Siegel, N.; Alexander, N. B.; Raffray, A. R.; Mau, T. K.; Tillack, M.; Najmabadi, F.; Krasheninnikov, S. I.; Gallix, R.


    In inertial fusion energy (IFE) power plant designs, the fuel is a spherical layer of frozen DT contained in a target that is injected at high velocity into the reaction chamber. For direct drive, typically laser beams converge at the centre of the chamber (CC) to compress and heat the target to fusion conditions. To obtain the maximum energy yield from the fusion reaction, the frozen DT layer must be at about 18.5 K and the target must maintain a high degree of spherical symmetry and surface smoothness when it reaches the CC. During its transit in the chamber the cryogenic target is heated by radiation from the hot chamber wall. The target is also heated by convection as it passes through the rarefied fill-gas used to control chamber wall damage by x-rays and debris from the target explosion. This article addresses the temperature limits at the target surface beyond which target uniformity may be damaged. It concentrates on direct drive targets because fuel warm up during injection is not currently thought to be an issue for present indirect drive designs and chamber concepts. Detailed results of parametric radiative and convective heating calculations are presented for direct-drive targets during injection into a dry-wall reaction chamber. The baseline approach to target survival utilizes highly reflective targets along with a substantially lower chamber wall temperature and fill-gas pressure than previously assumed. Recently developed high-Z material coatings with high heat reflectivity are discussed and characterized. The article also presents alternate target protection methods that could be developed if targets with inherent survival features cannot be obtained within a reasonable time span.

  7. About methods to reduce emissions of turbo charged engine gasoline direct injection (United States)

    Neacsu, D.; Ivan, F.; Niculae, M.


    The paper aims to analyse and explain new methods applied on gasoline direct injection to reduce gas emissions and greenhouse effect. There are analysed the composition of emission inside the engine and which are the most harmful emission for the environment. Will be analysed the methods and systems which have a contribution to decrease emissions produced by the mixture of air and fuel. The paper contains details about after treatment systems which are designed to decrease gas emissions without any other negative consequence on the environment.

  8. Direct injection of functional single-domain antibodies from E. coli into human cells.

    Directory of Open Access Journals (Sweden)

    Ana Blanco-Toribio

    Full Text Available Intracellular proteins have a great potential as targets for therapeutic antibodies (Abs but the plasma membrane prevents access to these antigens. Ab fragments and IgGs are selected and engineered in E. coli and this microorganism may be also an ideal vector for their intracellular delivery. In this work we demonstrate that single-domain Ab (sdAbs can be engineered to be injected into human cells by E. coli bacteria carrying molecular syringes assembled by a type III protein secretion system (T3SS. The injected sdAbs accumulate in the cytoplasm of HeLa cells at levels ca. 10⁵-10⁶ molecules per cell and their functionality is shown by the isolation of sdAb-antigen complexes. Injection of sdAbs does not require bacterial invasion or the transfer of genetic material. These results are proof-of-principle for the capacity of E. coli bacteria to directly deliver intracellular sdAbs (intrabodies into human cells for analytical and therapeutic purposes.

  9. Stroke from Delayed Embolization of Polymerized Glue Following Percutaneous Direct Injection of a Carotid Body Tumor

    Energy Technology Data Exchange (ETDEWEB)

    Krishnamoorthy, Thamburaj; Gupta, Arun Kumar; Rajan, Jayadevan E; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, (India)


    Direct percutaneous embolization of hypervascular tumors results in more effective preoperative devascularization. Migration of glue is a well known complication of direct glue injection and it may lead to stroke or cranial nerve deficits. We report here on a case of carotid body tumor in a 52-year-old man; the tumor was mainly embolized by percutaneous injection of 50% glue and this was supported with balloon protection of the internal carotid artery. Thirteen hours later, he developed hemiparesis from delayed migration of glue. The possible mechanisms of this migration are discussed and preventive measures are suggested. Preoperative embolization of hypervascular tumors of the head and neck, including carotid body tumor, is often performed to decrease the amount of blood loss during surgery. Devascularization is mainly performed with particulate agents and by employing the transarterial route. More effective embolization may be achieved by performing percutaneous direct embolization of hypervascular tumors with liquid embolic agents. Even though there are few reports available on direct embolization, complications from glue migration have been reported, and this mainly happens during the procedure when the glue is in a liquid state. We report here on a case of delayed migration of polymerized glue (n-butyl-2-cyanoacrylate [NBCA]), many hours after the procedure, into the intracranial circulation and the final result was stroke. A 52-year-old male with right carotid body tumor underwent direct percutaneous glue (n-butylcyanoacrylate [NBCA]) embolization. Several hours later, he developed left hemiparesis from embolization of the polymerized glue cast. Migration of glue during percutaneous tumor embolization is presumed to occur only in the liquid state, which may lead to stroke or cranial nerve deficits. To the best of our knowledge, this is the first report of delayed glue embolization from a treated hypervascular tumor of the head and neck.

  10. Burn Pits (United States)

    ... Enter ZIP code here Enter ZIP code here Burn Pits Burn Pits Registry Studies Photo: U.S. Department ... the health of deployed Veterans. Health effects from burn pit smoke Toxins in burn pit smoke may ...

  11. Burn Institute (United States)

    ... Now Help keep local seniors safe from fire! Burn Survivor Support If you are reading this, chances ... year – a burn injury. Learn more Fire and Burn Prevention Each year, the Burn Institute provides fire ...

  12. Cellular changes following direct vitamin D injection into the uraemia-induced hyperplastic parathyroid gland (United States)

    Shiizaki, Kazuhiro; Hatamura, Ikuji; Negi, Shigeo; Nakazawa, Eiko; Tozawa, Ryoko; Izawa, Sayoko; Akizawa, Tadao; Kusano, Eiji


    Background. Hyperplasia of the parathyroid gland (PTG) is associated not only with excessive secretion of parathyroid hormone (PTH) but also with changes in the parathyroid cell (PTC) characteristics (i.e. hyperproliferative activity and low contents of vitamin D and calcium-sensing receptors). The control of PTG hyperplasia is most important in the management of secondary hyperparathyroidism (SHPT), because the advanced stage of hyperplasia is considered irreversible. For the better control of the PTH level in dialysis patients with such advanced SHPT, percutaneous vitamin D injection therapy (PDIT) under ultrasonographic guidance was developed and various cellular changes caused by this treatment were also investigated using an animal model. Methods. The PTGs of Sprague–Dawley rats, which had been 5/6-nephrectomized and fed a high-phosphate diet, were treated with the direct injections of vitamin D agents, and cellular effects focusing the above-mentioned characters were investigated. Results. An adequacy of the direct injection technique into the rats’ PTGs and the successful effects of this treatment in various biochemical parameters were confirmed. Such characteristics of advanced SHPT were simultaneously improved; in particular, it was confirmed that this treatment may be effective in controlling PTG hyperplasia by, at least in part, apoptosis-induced cell death. Conclusions. A locally high level of vitamin D strongly may suppress PTH secretion and regress hyperplasia, which is involved in the induction of apoptosis in PTCs, based on the simultaneous improvements of cellular characters of advanced SHPT. The PTH control introduced by this treatment successfully ameliorated osteitis fibrosa (high bone turnover rate). PMID:25983973

  13. Cellular changes following direct vitamin D injection into the uraemia-induced hyperplastic parathyroid gland. (United States)

    Shiizaki, Kazuhiro; Hatamura, Ikuji; Negi, Shigeo; Nakazawa, Eiko; Tozawa, Ryoko; Izawa, Sayoko; Akizawa, Tadao; Kusano, Eiji


    Background. Hyperplasia of the parathyroid gland (PTG) is associated not only with excessive secretion of parathyroid hormone (PTH) but also with changes in the parathyroid cell (PTC) characteristics (i.e. hyperproliferative activity and low contents of vitamin D and calcium-sensing receptors). The control of PTG hyperplasia is most important in the management of secondary hyperparathyroidism (SHPT), because the advanced stage of hyperplasia is considered irreversible. For the better control of the PTH level in dialysis patients with such advanced SHPT, percutaneous vitamin D injection therapy (PDIT) under ultrasonographic guidance was developed and various cellular changes caused by this treatment were also investigated using an animal model. Methods. The PTGs of Sprague-Dawley rats, which had been 5/6-nephrectomized and fed a high-phosphate diet, were treated with the direct injections of vitamin D agents, and cellular effects focusing the above-mentioned characters were investigated. Results. An adequacy of the direct injection technique into the rats' PTGs and the successful effects of this treatment in various biochemical parameters were confirmed. Such characteristics of advanced SHPT were simultaneously improved; in particular, it was confirmed that this treatment may be effective in controlling PTG hyperplasia by, at least in part, apoptosis-induced cell death. Conclusions. A locally high level of vitamin D strongly may suppress PTH secretion and regress hyperplasia, which is involved in the induction of apoptosis in PTCs, based on the simultaneous improvements of cellular characters of advanced SHPT. The PTH control introduced by this treatment successfully ameliorated osteitis fibrosa (high bone turnover rate).


    National Research Council Canada - National Science Library

    K R Patil; S S Thipse


      An experimental investigation has been carried out to evaluate the effect of kerosene as an additive to diesel fuel on the combustion, performance and emission characteristics of a direct-injection...

  15. Polymer-Derived In- Situ Metal Matrix Composites Created by Direct Injection of a Liquid Polymer into Molten Magnesium (United States)

    Sudarshan; Terauds, Kalvis; Anilchandra, A. R.; Raj, Rishi


    We show that a liquid organic precursor can be injected directly into molten magnesium to produce nanoscale ceramic dispersions within the melt. The castings made in this way possess good resistance to tensile deformation at 673 K (400 °C), confirming the non-coarsening nature of these dispersions. Direct liquid injection into molten metals is a significant step toward inserting different chemistries of liquid precursors to generate a variety of polymer-derived metal matrix composites.

  16. Combustion processes for a low pressure gasoline direct injection; Brennverfahrenskonzepte fuer eine Niederdruck-Direkteinspritzung bei Ottomotoren

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Stephan; Trattner, Alexander; Eichlseder, Helmut; Kirchberger, Roland [Technische Univ., Graz (Austria). Inst. fuer Verbrennungskraftmaschinen und Thermodynamik


    The gasoline direct injection becomes more and more important for small engines used in passenger cars. Lowering injection pressure and thus costs could enable the introduction of this technology in the small engine segment offering an alternative to today's MPFI engines. The results of these investigations made at TU Graz show the potential of low pressure direct injection in terms of improvement over standard MPFI engines (fuel economy, emissions, and engine operation stability) and reduced costs compared to high pressure GDI systems. (orig.)

  17. Computational Study of Combustion Dynamics in a Single-Element Lean Direct Injection Gas Turbine Combustor (United States)


    spray injection models , viz., Log Normal Distributed Drop Injection Model , Single Drop Injection Model and Hollow Cone Injection Model , have...not match experiment. The hollow cone injection model was able to predict the correct dominant acoustic mode (4L) but the pressure amplitude was...processes of pressure-swirl hollow - cone fuel sprays ," Atomization and Sprays , vol. 7, pp. 663-684, Nov-Dec 1997. 22 M. A. Patterson and R. D.

  18. Performance Analysis of AP1000 Passive Systems during Direct Vessel Injection (DVI Line Break

    Directory of Open Access Journals (Sweden)

    A.S. Ekariansyah


    Full Text Available Generation II Nuclear Power Plants (NPPs have a design weakness as shown by the Fukushima accident. Therefore, Generation III+ NPPs are developed with focus on improvements of fuel technology and thermal efficiency, standardized design, and the use of passive safety system. One type of Generation III+ NPP is the AP1000 that is a pressurized water reactor (PWR type that has received the final design acceptance from US-NRC and is already under construction at several sites in China as of 2015. The aim of this study is to investigate the behavior and performance of the passive safety system in the AP1000 and to verify the safety margin during the direct vessel injection (DVI line break as selected event. This event was simulated using RELAP5/SCDAP/Mod3.4 as a best-estimate code developed for transient simulation of light water reactors during postulated accidents. This event is also described in the AP1000 design control document as one of several postulated accidents simulated using the NOTRUMP code. The results obtained from RELAP5 calculation was then compared with the results of simulations using the NOTRUMP code. The results show relatively good agreements in terms of time sequences and characteristics of some injected flow from the passive safety system. The simulation results show that the break of one of the two available DVI lines can be mitigated by the injected coolant flowing, which is operated effectively by gravity and density difference in the cooling system and does not lead to core uncovery. Despite the substantial effort to obtain an apropriate AP1000 model due to lack of detailed geometrical data, the present model can be used as a platform model for other initiating event considered in the AP1000 accident analysis.

  19. Assessing the Climate Trade-Offs of Gasoline Direct Injection Engines. (United States)

    Zimmerman, Naomi; Wang, Jonathan M; Jeong, Cheol-Heon; Wallace, James S; Evans, Greg J


    Compared to port fuel injection (PFI) engine exhaust, gasoline direct injection (GDI) engine exhaust has higher emissions of black carbon (BC), a climate-warming pollutant. However, the relative increase in BC emissions and climate trade-offs of replacing PFI vehicles with more fuel efficient GDI vehicles remain uncertain. In this study, BC emissions from GDI and PFI vehicles were compiled and BC emissions scenarios were developed to evaluate the climate impact of GDI vehicles using global warming potential (GWP) and global temperature potential (GTP) metrics. From a 20 year time horizon GWP analysis, average fuel economy improvements ranging from 0.14 to 14% with GDI vehicles are required to offset BC-induced warming. For all but the lowest BC scenario, installing a gasoline particulate filter with an 80% BC removal efficiency and engine operation, and fuel composition. More work is needed to understand BC formation mechanisms in GDI engines to ensure that the climate impacts of this engine technology are minimal.

  20. Numerical studies of spray breakup in a gasoline direct injection (GDI engine

    Directory of Open Access Journals (Sweden)

    Jafarmadar Samad


    Full Text Available The objective of this study is to investigate Spray Breakup process of sprays injected from single and two-hole nozzles for gasoline direct Injection (GDI engines by using three dimensional CFD code. Spray characteristics were examined for spray tip penetration and other characteristics including: the vapor phase concentration distribution and droplet spatial distribution, which were acquired using the computational fluid dynamics (CFD simulation. Results showed that as the hole-axis-angle (γ of the two-hole nozzle decreased, the droplet coalescence increased and vapor mass decreased. The spray with cone angle (θ0 5 deg for single hole nozzle has the longest spray tip penetration and the spray with the γ of 30 deg and spray cone angle θ0=30 deg for two hole nozzles had the shortest one. Also, when the spray cone angle (θ0 and hole-axis-angle (γ increased from 5 to 30 deg, the Sauter mean diameter (SMD decreased for both single-hole and two-hole nozzles used in this study. For a single-hole nozzle, when spray cone angle increased from 5 to 30 deg, the vaporization rate very much because of low level of coalescence. The result of model for tip penetration is good agreement with the corresponding experimental data in the literatures.

  1. Direct injection HPLC method for the determination of selected benzodiazepines in plasma using a Hisep column. (United States)

    Pistos, C; Stewart, James T


    A direct plasma injection HPLC method has been developed for the determination of selected benzodiazepines (nitrazepam, clobazam, oxazepam, lorazepam). The method uses an analytical hydrophobic shielded phase (Hisep) column equipped with a Hisep guard column, are easy to perform and requires 20 ul of a filtered plasma sample. The chromatographic run time is less than 15 min using a mobile phase of 15:85 v/v acetonitrile-0.18 M ammonium acetate pH 2.5. The method is good for 175 injections before replacement of the guard column. The method was linear in the range 0.5-18 ug ml(-1) (r>0.99, n=6) for the analytes with R.S.D. less than 10.82%. Interday and intraday variability were found to be less than 14%. The limits of detection and quantitation were 0.16 (s/n>3) and 0.5 ug ml(-1) (s/n>10), respectively, for each of the four benzodiazepines.

  2. Aqueous-phase photochemical oxidation and direct photolysis of vanillin - a model compound of methoxy-phenols from biomass burning (United States)

    Li, Y. J.; Huang, D. D.; Cheung, H. Y.; Lee, A. K. Y.; Chan, C. K.


    We present here experimental results on aqueous-phase (A) photochemical oxidation (with UV and OH radicals generated from H2O2 photolysis) and (B) direct photolysis (with only UV irradiation) of a methoxy-phenol, vanillin (VL), as a model compound from biomass burning. Both on-line aerosol mass spectrometric (AMS) characterization and off-line chemical analyses were performed. AMS analyses of dried atomized droplets of the bulk reacting mixtures showed that VL almost entirely evaporates during the drying process. Large amounts of organic mass remained in the particle phase after reactions under both conditions. Under condition (A), AMS measured organic mass first increased rapidly and then decreased, attributable to the formation of non-volatile products and subsequent formation of smaller and volatile products, respectively. The oxygen-to-carbon (O:C) ratio of the products reached 1.5 after about 80 min, but dropped substantially thereafter. In contrast, organic mass increased slowly under condition (B). The O:C ratio reached 1.0 after 180 min. In off-line analyses, small oxygenates were detected under condition (A), while hydroxylated products and dimers of VL were detected under condition (B). Particle hygroscopic growth factor (GF) and cloud condensation nuclei (CCN) activity of the reacting mixtures were found to be dependent on both organic volume fraction and the degree of oxygenation of organics. Results show that (1) aqueous-phase processes can lead to the retention of a large portion of the organic mass in the particle phase; (2) once retained, this portion of organic mass significantly changes the hygroscopicity and CCN activity of the aerosol particles; (3) intensive photochemical oxidation gave rise to an O:C ratio as high as 1.5 but the ratio decreased as further oxidation led to smaller and more volatile products; and (4) polymerization occurred with direct photolysis, resulting in high-molecular-weight products of a yellowish color. This study

  3. Aqueous-phase photochemical oxidation and direct photolysis of vanillin - a model compound of methoxy phenols from biomass burning (United States)

    Li, Y. J.; Huang, D. D.; Cheung, H. Y.; Lee, A. K. Y.; Chan, C. K.


    We present here experimental results on aqueous-phase (A) photochemical oxidation (with UV and OH radicals generated from H2O2 photolysis) and (B) direct photolysis (with only UV irradiation) of a methoxy phenol, vanillin (VL), as a model compound from biomass burning. Both on-line aerosol mass spectrometric (AMS) characterization and off-line chemical analyses were performed. AMS analyses of dried atomized droplets of the bulk reacting mixtures showed that VL almost entirely evaporates during the drying process. Large amounts of organic mass remained in the particle phase after reactions under both conditions. Under condition (A), AMS measured organic mass first increased rapidly and then decreased, attributable to the formation of non-volatile products and subsequent formation of smaller and volatile products, respectively. The oxygen-to-carbon (O : C) ratio of the products reached 1.5 after about 80 min, but dropped substantially thereafter. In contrast, organic mass increased slowly under condition (B). The O : C ratio reached 1.0 after 180 min. In off-line analyses, small oxygenates were detected under condition (A), while hydroxylated products and dimers of VL were detected under condition (B). Particle hygroscopic growth factor (GF) and cloud condensation nuclei (CCN) activity of the reacting mixtures were found to depend on both organic volume fraction and the degree of oxygenation of organics. Results show that (1) aqueous-phase processes can lead to the retention of a large portion of the organic mass in the particle phase; (2) once retained, this portion of organic mass significantly changes the hygroscopicity and CCN activity of the aerosol particles; (3) intensive photochemical oxidation gave rise to an O : C ratio as high as 1.5 but the ratio decreased as further oxidation led to smaller and more volatile products; and (4) polymerization occurred with direct photolysis, resulting in high-molecular-weight products of a yellowish color. This study

  4. Application of an EGR system in a direct injection diesel engine to reduce NOx emissions (United States)

    De Serio, D.; De Oliveira, A.; Sodré, J. R.


    This work presents the application of an exhaust gas recirculation (EGR) system in a direct injection diesel engine operating with diesel oil containing 7% biodiesel (B7). EGR rates of up to 10% were applied with the primary aim to reduce oxides of nitrogen (NOx) emissions. The experiments were conducted in a 44 kW diesel power generator to evaluate engine performance and emissions for different load settings. The use of EGR caused a peak pressure reduction during the combustion process and a decrease in thermal efficiency, mainly at high engine loads. A reduction of NOx emissions of up to 26% was achieved, though penalizing carbon monoxide (CO) and total hydrocarbons (THC) emissions.

  5. Experimental Investigation of Performance and Emissions of a Stratified Charge CNG Direct Injection Engine with Turbocharger

    Directory of Open Access Journals (Sweden)

    Amiruddin Hilmi


    Full Text Available This paper presents the results from 1.6 litre, 4 cylinders stratified charge compressed natural gas (CNG direct injection engine with boosting device. A turbocharger with compressor trim of 40 was used to increase engine output. The engine was tested at wide open throttle (WOT and speed ranging from 1000 to 5000 rpm. Engine performance and emissions data were recorded under steady state condition. Results show turbocharged CNG engine produced an average of 26% increment in brake power and 24% additional maximum brake torque as compared with natural aspirated (NA CNG engine. Turbocharged CNG engine improved brake specific fuel consumption (BSFC and yielded higher fuel conversion efficiency (FCE. Relatively turbocharged CNG engine showed lower emission of hydrocarbon (HC and carbon monoxide (CO throughout tested engine speed. Conversely, the carbon dioxide (CO2 and nitrogen oxide (NOx emission produced were slightly higher compared with NA CNG engine.

  6. Role of Direct Laser Acceleration of Electrons in a Laser Wakefield Accelerator with Ionization Injection (United States)

    Shaw, J. L.; Lemos, N.; Amorim, L. D.; Vafaei-Najafabadi, N.; Marsh, K. A.; Tsung, F. S.; Mori, W. B.; Joshi, C.


    We show the first experimental demonstration that electrons being accelerated in a laser wakefield accelerator operating in the forced or blowout regimes gain significant energy from both the direct laser acceleration (DLA) and the laser wakefield acceleration mechanisms. Supporting full-scale 3D particle-in-cell simulations elucidate the role of the DLA of electrons in a laser wakefield accelerator when ionization injection of electrons is employed. An explanation is given for how electrons can maintain the DLA resonance condition in a laser wakefield accelerator despite the evolving properties of both the drive laser and the electrons. The produced electron beams exhibit characteristic features that are indicative of DLA as an additional acceleration mechanism.

  7. Experience of direct percutaneous sac injection in type II endoleak using cone beam computed tomography. (United States)

    Park, Yoong-Seok; Do, Young Soo; Park, Hong Suk; Park, Kwang Bo; Kim, Dong-Ik


    Cone beam CT, usually used in dental area, could easily obtain 3-dimensional images using cone beam shaped ionized radiation. Cone beam CT is very useful for direct percutaneous sac injection (DPSI) which needs very precise measurement to avoid puncture of inferior vena cava or vessel around sac or stent graft. Here we describe two cases of DPSI using cone beam CT. In case 1, a 79-year-old male had widening of preexisted type II endoleak after endovascular aneurysm repair (EVAR). However, transarterial embolization failed due to tortuous collateral branches of lumbar arteries. In case 2, a 72-year-old female had symptomatic sac enlargement by type II endoleak after EVAR. However, there was no route to approach the lumbar arteries. Therefore, we performed DPSI assisted by cone beam CT in cases 1, 2. Six-month CT follow-up revealed no sign of sac enlargement by type II endoleak.


    Directory of Open Access Journals (Sweden)



    Full Text Available Algal oil methyl ester was derived from microalgae (Spirulina sp. The microalga was cultivated in BG 11 media composition in a photobioreactor. Upon harvesting, the biomass was filtered and dried. The algal oil was obtained by a two step solvent extraction method using hexane and ether solvent. Cyclohexane was added to biomass to expel the remaining algal oil. By this method 92% of algal oil is obtained. Transesterification process was carried out to produce AOME by adding sodium hydroxide and methanol. The AOME was blended with straight diesel in 5%, 10% and 15% blend ratio. Combustion parameters were analyzed on a Kirloskar single cylinder direct injection compression ignition engine. The cylinder pressure characteristics, the rate of pressure rise, heat release analysis, performance and emissions were studied for straight diesel and the blends of AOME’s. AOME 15% blend exhibits significant variation in cylinder pressure and rate of heat release.

  9. An Idealized, Single Radial Swirler, Lean-Direct-Injection (LDI) Concept Meshing Script (United States)

    Iannetti, Anthony C.; Thompson, Daniel


    To easily study combustor design parameters using computational fluid dynamics codes (CFD), a Gridgen Glyph-based macro (based on the Tcl scripting language) dubbed BladeMaker has been developed for the meshing of an idealized, single radial swirler, lean-direct-injection (LDI) combustor. BladeMaker is capable of taking in a number of parameters, such as blade width, blade tilt with respect to the perpendicular, swirler cup radius, and grid densities, and producing a three-dimensional meshed radial swirler with a can-annular (canned) combustor. This complex script produces a data format suitable for but not specific to the National Combustion Code (NCC), a state-of-the-art CFD code developed for reacting flow processes.

  10. Determination of urinary vanillylmandelic acid by direct injection and coupled-column chromatography with electrochemical detection. (United States)

    Eriksson, B M; Persson, B A; Wikström, M


    An automated column-switching system for determination of vanillylmandelic acid in urine is described. The liquid chromatographic system was composed of two separation columns with different selectivity properties, an octadecyl column coated with tributyl phosphate as stationary liquid phase and a silica-based anion exchanger. Urine samples were injected directly onto the first column, where vanillylmandelic acid was separated from the main part of the sample matrix. The internal standard isovanillylmandelic acid was co-eluting with vanillylmandelic acid, and a fraction of the eluate containing both substances was switched to the second column, where separation was performed. To assess peak purity, detection was performed with dual working electrodes in parallel mode. A relative standard deviation of 3.5% was obtained for determination of human urine samples containing 3 microM vanillylmandelic acid, and less than 0.1 microM could be detected.

  11. Start of Injection Impacts on Performance of a Direct-injection Spark-ignition Engine%喷油开始时刻对缸内直喷汽油机性能的影响

    Institute of Scientific and Technical Information of China (English)

    韩文艳; 许思传; 周岳康; 任健康


    通过对某涡轮增压缸内直喷汽油机缸内流动、混合气形成及燃烧过程的数值模拟,并借助发动机台架试验中获得的油耗、排放及燃烧数据,研究了喷油开始时刻对发动机性能的影响.结果显示,对于5 000 r ·min-1工况,喷油开始时刻为400°曲轴转角是混合气雾化混合的最佳方案,此时混合气分布比较均匀且点火时刻火花塞附近具有较高的湍动能,10%~90%燃烧持续期最短且HC排放较低,从而使其具有最佳的燃油经济性与燃烧稳定性.而2 000 r· min-1工况的最佳喷油开始时刻推迟了30°曲轴转角.喷油提前,壁面油膜量增加,混合气当量比下降及火花塞附近较低的湍动能使得燃烧速率降低,因此HC排放、燃油经济性及燃烧稳定性均会变差.同样的情况也出现在推迟喷油中,由于混合不充分使得点火时刻混合气均匀度下降,从而使发动机性能恶化.%A numerical simulation was carried out on cylinder flow, mixture formation and combustion process of a turbo-charged gasoline direct injection engine, and then on the basis of the test data about the break specific fuel consumption, emission and combustion, an analysis was made of the best time to start the injection on engine performance.The results show in the case of 5 000 r·min-1, the injection started at 400° crank angle obtains an optimal mixture formation, when it presents the best fuel economy and combustion stability with distribution, the higher turbulence kinetic energy around the spark plug at spark time and the shortest 10% ~90% burning duration as well as the lower HC emission.While the best time to start the injection is retarded at 30° crank angle with 2 000 r·min-1.When the injection starts in advance, the wall film increases, and the decreased equivalence ratio and the lower turbulence kinetic energy around spark lead to a lower burning rate, so HC emissions, fuel economy and combustion stability may go bad

  12. Direct measurements of the effect of biomass burning over the Amazon on the atmospheric temperature profile

    Directory of Open Access Journals (Sweden)

    L. Remer


    Full Text Available Aerosols suspended in the atmosphere interact with solar radiation and clouds, thus change the radiation energy fluxes in the atmospheric column. In this paper we measure changes in the atmospheric temperature profile as a function of the smoke loading and the cloudiness, over the Amazon basin, during the dry seasons (August and September of 2005–2008. We show that as the aerosol optical depth (AOD increases from 0.02 to a value of ~0.6, there is a decrease of ~4°C at 1000 hPa, and an increase of ~1.5°C at 850 hPa. The warming of the aerosol layer at 850 hPa is likely due to aerosol absorption when the particles are exposed to direct illumination by the sun. The large values of cooling in the lower layers could be explained by a combination of aerosol extinction of the solar flux in the layers aloft together with an aerosol-induced increase of cloud cover which shade the lower atmosphere. We estimate that the increase in cloud fraction due to aerosol contributes about half of the observed cooling in the lower layers.

  13. Direct Top-down Estimates of Biomass Burning CO Emissions Using TES and MOPITT Versus Bottom-up GFED Inventory (United States)

    Pechony, Olga; Shindell, Drew T.; Faluvegi, Greg


    In this study, we utilize near-simultaneous observations from two sets of multiple satellite sensors to segregate Tropospheric Emission Spectrometer (TES) and Measurements of Pollution in the Troposphere (MOPITT) CO observations over active fire sources from those made over clear background. Hence, we obtain direct estimates of biomass burning CO emissions without invoking inverse modeling as in traditional top-down methods. We find considerable differences between Global Fire Emissions Database (GFED) versions 2.1 and 3.1 and satellite-based emission estimates in many regions. Both inventories appear to greatly underestimate South and Southeast Asia emissions, for example. On global scales, however, CO emissions in both inventories and in the MOPITT-based analysis agree reasonably well, with the largest bias (30%) found in the Northern Hemisphere spring. In the Southern Hemisphere, there is a one-month shift between the GFED and MOPITT-based fire emissions peak. Afternoon tropical fire emissions retrieved from TES are about two times higher than the morning MOPITT retrievals. This appears to be both a real difference due to the diurnal fire activity variations, and a bias due to the scarcity of TES data.

  14. Correcting the Science Record: Direct Stratospheric Injection vs. Asian Monsoon and the Solar Escalator (United States)

    Fromm, M. D.; Nedoluha, G. E.; Kablick, G. P.


    Two entries in the literature in 2012 make provocative but unsupportable claims regarding pollutant pathways from the Earth to the stratosphere. One claims the 13 June 2011 Nabro volcano (Eritrea) emitted gases and particles into the troposphere, and these constituents reached the stratosphere in great abundance via the Asian Monsoon circulation [Bourassa et al., 2012]. The other claims that smoke from the Black Saturday fire storms (Australia) was emitted into the troposphere, and was lofted ~15 km into the stratosphere by solar-induced diabatic heating [de Laat et al., 2012]. In both cases the stratospheric plumes attributed to these events spread around the globe and lasted for months. We will show that in both cases the postulated pathways are incorrect; the correct pathway is a direct convective injection by volcanic eruption and pyrocumulonimbus (pyroCb), respectively. We will present satellite data that will unambiguously reveal multiple, distinct stratospheric volcano-convection columns from Nabro connected to height-resolved volcanic SO2 and sulfate particles. In the case of Black Saturday we will characterize the pyroCb columns with ground-based radar and satellite imagery. The young pyroCb plume in the stratosphere will be characterized with a synergistic analysis of several NASA A-Train passive and active remote sensors. We will discuss the implications of our findings with respect to how satellite-based data are best used for tracking and characterizing point source injection plumes in the stratosphere. Bourassa et al. (2012), Large Volcanic Aerosol Load in the Stratosphere Linked to Asian Monsoon Transport, Science, 337, 78, DOI: 10:1126/Science.1219371 de Laat, et al. (2012), A solar escalator: Observational evidence of the self-lifting of smoke and aerosols by absorption of solar radiation in the February 2009 Australian Black Saturday plume, J. Geophys. Res., 117, D04204, doi:10.1029/2011JD017016.

  15. Release of biomarkers of myocardial damage after direct intramyocardial injection of genes and stem cells via the percutaneous transluminal route

    DEFF Research Database (Denmark)

    Baldazzi, F.; Jørgensen, Erik; Ripa, R.S.;


    no patient in the group receiving 0.2 mL had a more than two-fold CKMB increase. No patient developed new ECG changes. There were no clinically ventricular arrhythmias and no death. CONCLUSION: NOGA mapping followed by direct intramyocardial injections of stem cells or genes lead to measurable release......AIMS: We aimed to quantify the release of biomarkers of myocardial damage in relation to direct intramyocardial injections of genes and stem cells in patients with severe coronary artery disease. METHODS AND RESULTS: We studied 71 patients with 'no-option' coronary artery disease. Patients had, via...

  16. Combustion characteristics of a 4-stroke CI engine operated on Honge oil, Neem and Rice Bran oils when directly injected and dual fuelled with producer gas induction

    Energy Technology Data Exchange (ETDEWEB)

    Banapurmath, N.R.; Tewari, P.G. [Department of Mechanical Engineering, B.V.B. College of Engineering and Technology, Hubli 580031, Karnataka (India); Yaliwal, V.S. [Department of Mechanical Engineering, SDM College of Engineering and Technology, Dharwad Karnataka (India); Kambalimath, Satish [Wipro Technologies (India); Basavarajappa, Y.H. [K.L.E. Society' s Polytechnic, Hubli (India)


    Energy is an essential requirement for economic and social development of any country. Sky rocketing of petroleum fuel costs in present day has led to growing interest in alternative fuels like vegetable oils, alcoholic fuels, CNG, LPG, Producer gas, biogas in order to provide a suitable substitute to diesel for a compression ignition (CI) engine. The vegetable oils present a very promising alternative fuel to diesel oil since they are renewable, biodegradable and clean burning fuel having similar properties as that of diesel. They offer almost same power output with slightly lower thermal efficiency due to their lower energy content compared to diesel. Utilization of producer gas in CI engine on dual fuel mode provides an effective approach towards conservation of diesel fuel. Gasification involves conversion of solid biomass into combustible gases which completes combustion in a CI engines. Hence the producer gas can act as promising alternative fuel and it has high octane number (100-105) and calorific value (5-6 MJ/Nm{sup 3}). Because of its simpler structure with low carbon content results in substantial reduction of exhaust emission. Downdraft moving bed gasifier coupled with compression ignition engine are a good choice for moderate quantities of available mass up to 500 kW of electrical power. Hence bio-derived gas and vegetable liquids appear more attractive in view of their friendly environmental nature. Experiments have been conducted on a single cylinder, four-stroke, direct injection, water-cooled CI engine operated in single fuel mode using Honge, Neem and Rice Bran oils. In dual fuel mode combinations of Producer gas and three oils were used at different injection timings and injection pressures. Dual fuel mode of operation resulted in poor performance at all the loads when compared with single fuel mode at all injection timings tested. However, the brake thermal efficiency is improved marginally when the injection timing was advanced. Decreased

  17. Field Measurements of Gasoline Direct Injection Emission Factors: Spatial and Seasonal Variability. (United States)

    Zimmerman, Naomi; Wang, Jonathan M; Jeong, Cheol-Heon; Ramos, Manuel; Hilker, Nathan; Healy, Robert M; Sabaliauskas, Kelly; Wallace, James S; Evans, Greg J


    Four field campaigns were conducted between February 2014 and January 2015 to measure emissions from light-duty gasoline direct injection (GDI) vehicles (2013 Ford Focus) in an urban near-road environment in Toronto, Canada. Measurements of CO2, CO, NOx, black carbon (BC), benzene, toluene, ethylbenzene-xylenes (BTEX), and size-resolved particle number (PN) were recorded 15 m from the roadway and converted to fuel-based emission factors (EFs). Other than for NOx and CO, the GDI engine had elevated emissions compared to the Toronto fleet, with BC EFs in the 73rd percentile, BTEX EFs in the 80-90th percentile, and PN EFs in the 75th percentile during wintertime measurements. Additionally, for three campaigns, a second platform for measuring PN and CO2 was placed 1.5-3 m from the roadway to quantify changes in PN with distance from point of emission. GDI vehicle PN EFs were found to increase by up to 240% with increasing distance from the roadway, predominantly due to an increasing fraction of sub-40 nm particles. PN and BC EFs from the same engine technology were also measured in the laboratory. BC EFs agreed within 20% between the laboratory and real-world measurements; however, laboratory PN EFs were an order of magnitude lower due to exhaust conditioning.

  18. Comparison of Propane and Methane Performance and Emissions in a Turbocharged Direct Injection Dual Fuel Engine

    Energy Technology Data Exchange (ETDEWEB)

    Gibson, C. M.; Polk, A. C.; Shoemaker, N. T.; Srinivasan, K. K.; Krishnan, S. R.


    With increasingly restrictive NO x and particulate matter emissions standards, the recent discovery of new natural gas reserves, and the possibility of producing propane efficiently from biomass sources, dual fueling strategies have become more attractive. This paper presents experimental results from dual fuel operation of a four-cylinder turbocharged direct injection (DI) diesel engine with propane or methane (a natural gas surrogate) as the primary fuel and diesel as the ignition source. Experiments were performed with the stock engine control unit at a constant speed of 1800 rpm, and a wide range of brake mean effective pressures (BMEPs) (2.7-11.6 bars) and percent energy substitutions (PESs) of C 3 H 8 and CH 4. Brake thermal efficiencies (BTEs) and emissions (NO x, smoke, total hydrocarbons (THCs), CO, and CO 2) were measured. Maximum PES levels of about 80-95% with CH 4 and 40-92% with C 3 H 8 were achieved. Maximum PES was limited by poor combustion efficiencies and engine misfire at low loads for both C 3 H 8 and CH 4, and the onset of knock above 9 bar BMEP for C 3 H 8. While dual fuel BTEs were lower than straight diesel BTEs at low loads, they approached diesel BTE values at high loads. For dual fuel operation, NO x and smoke reductions (from diesel values) were as high as 66-68% and 97%, respectively, but CO and THC emissions were significantly higher with increasing PES at all engine loads

  19. National Combustion Code Validated Against Lean Direct Injection Flow Field Data (United States)

    Iannetti, Anthony C.


    Most combustion processes have, in some way or another, a recirculating flow field. This recirculation stabilizes the reaction zone, or flame, but an unnecessarily large recirculation zone can result in high nitrogen oxide (NOx) values for combustion systems. The size of this recirculation zone is crucial to the performance of state-of-the-art, low-emissions hardware. If this is a large-scale combustion process, the flow field will probably be turbulent and, therefore, three-dimensional. This research dealt primarily with flow fields resulting from lean direct injection (LDI) concepts, as described in Research & Technology 2001. LDI is a concept that depends heavily on the design of the swirler. The LDI concept has the potential to reduce NOx values from 50 to 70 percent of current values, with good flame stability characteristics. It is cost effective and (hopefully) beneficial to do most of the design work for an LDI swirler using computer-aided design (CAD) and computer-aided engineering (CAE) tools. Computational fluid dynamics (CFD) codes are CAE tools that can calculate three-dimensional flows in complex geometries. However, CFD codes are only beginning to correctly calculate the flow fields for complex devices, and the related combustion models usually remove a large portion of the flow physics.

  20. The Effect of Ethanol-Diesel Blends on The Performance of A Direct Injection Diesel Engine

    Directory of Open Access Journals (Sweden)

    Arifin Nur


    Full Text Available The experiment was conducted on a conventional direct injection diesel engine. Performance test was carried out to evaluate the performance and emission characteristics of a conventional diesel engine that operates on ethanol-diesel blends. The test procedure was performed by coupling the diesel engine on the eddy current dynamometer. Fuel consumption was measured using the AVL Fuel Balance, and a hotwire anemometer was used to measure the air consumption. Some of the emission test devices were mounted on the exhaust pipe. The test of fuel variations started from 100% diesel fuel (D100 to 2.5% (DE2.5, 5% (DE5, 7.5% (DE7.5, and 10% (DE10 ethanol additions. Performance test was conducted at 1500 rpm with load variations from 0 to 60 Nm by increasing the load on each level by 10 Nm. The addition of 5% ethanol to diesel (DE5 increased the average pressure of combustion chamber indication to 48% as well as reduced the specific fuel consumption to 9.5%. There were better exhaust emission characteristics at this mixture ratio than diesel engine which used pure diesel fuel (D100, the reduction of CO to 37%, HC to 44% and opacity to 15.9%.

  1. A Comparison of Combustion Dynamics for Multiple 7-Point Lean Direct Injection Combustor Configurations (United States)

    Tacina, K. M.; Hicks, Y. R.


    The combustion dynamics of multiple 7-point lean direct injection (LDI) combustor configurations are compared. LDI is a fuel-lean combustor concept for aero gas turbine engines in which multiple small fuel-air mixers replace one traditionally-sized fuel-air mixer. This 7-point LDI configuration has a circular cross section, with a center (pilot) fuel-air mixer surrounded by six outer (main) fuel-air mixers. Each fuel-air mixer consists of an axial air swirler followed by a converging-diverging venturi. A simplex fuel injector is inserted through the center of the air swirler, with the fuel injector tip located near the venturi throat. All 7 fuel-air mixers are identical except for the swirler blade angle, which varies with the configuration. Testing was done in a 5-atm flame tube with inlet air temperatures from 600 to 800 F and equivalence ratios from 0.4 to 0.7. Combustion dynamics were measured using a cooled PCB pressure transducer flush-mounted in the wall of the combustor test section.

  2. Multi-Segment Direct Inject nano-ESI-LTQ-FT-ICR-MS/MS For Protein Identification. (United States)

    Chen, Jing; Canales, Lorena; Neal, Rachel E


    Reversed phase high performance liquid chromatography (HPLC) interfaced to electrospray tandem mass spectrometry (MS/MS) is commonly used for the identification of peptides from proteolytically cleaved proteins embedded in a polyacrylamide gel matrix as well as for metabolomics screening. HPLC separations are time consuming (30-60 min average), costly (columns and mobile phase reagents), and carry the risk of column carry over between samples. The use of a chip-based nano-ESI platform (Advion NanoMate) based on replaceable nano-tips for sample introduction eliminates sample cross-contamination, provides unchanging sample matrix, and enhances spray stability with attendant increases in reproducibility. Recent papers have established direct infusion nano-ESI-MS/MS utilizing the NanoMate for protein identification of gel spots based on full range MS scans with data dependent MS/MS. In a full range scan, discontinuous ion suppression due to sample matrix can impair identification of putative mass features of interest in both the proteomic and metabolomic workflows. In the current study, an extension of an established direct inject nano-ESI-MS/MS method is described that utilizes the mass filtering capability of an ion-trap for ion packet separation into four narrow mass ranges (50 amu overlap) with segment specific dynamic data dependent peak inclusion for MS/MS fragmentation (total acquisition time of 3 minutes). Comparison of this method with a more traditional nanoLC-MS/MS based protocol utilizing solvent/sample stream splitting to achieve nanoflow demonstrated comparable results for protein identification from polyacrylamide gel matrices. The advantages of this method include full automation, lack of cross-contamination, low cost, and high throughput.

  3. Multi-Segment Direct Inject nano-ESI-LTQ-FT-ICR-MS/MS For Protein Identification

    Directory of Open Access Journals (Sweden)

    Neal Rachel E


    Full Text Available Abstract Reversed phase high performance liquid chromatography (HPLC interfaced to electrospray tandem mass spectrometry (MS/MS is commonly used for the identification of peptides from proteolytically cleaved proteins embedded in a polyacrylamide gel matrix as well as for metabolomics screening. HPLC separations are time consuming (30-60 min average, costly (columns and mobile phase reagents, and carry the risk of column carry over between samples. The use of a chip-based nano-ESI platform (Advion NanoMate based on replaceable nano-tips for sample introduction eliminates sample cross-contamination, provides unchanging sample matrix, and enhances spray stability with attendant increases in reproducibility. Recent papers have established direct infusion nano-ESI-MS/MS utilizing the NanoMate for protein identification of gel spots based on full range MS scans with data dependent MS/MS. In a full range scan, discontinuous ion suppression due to sample matrix can impair identification of putative mass features of interest in both the proteomic and metabolomic workflows. In the current study, an extension of an established direct inject nano-ESI-MS/MS method is described that utilizes the mass filtering capability of an ion-trap for ion packet separation into four narrow mass ranges (50 amu overlap with segment specific dynamic data dependent peak inclusion for MS/MS fragmentation (total acquisition time of 3 minutes. Comparison of this method with a more traditional nanoLC-MS/MS based protocol utilizing solvent/sample stream splitting to achieve nanoflow demonstrated comparable results for protein identification from polyacrylamide gel matrices. The advantages of this method include full automation, lack of cross-contamination, low cost, and high throughput.

  4. Enfuvirtide Injection (United States)

    ... inject enfuvirtide into any skin that has a tattoo, scar, bruise, mole, a burn site, or has ... Enfuvirtide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: itching, swelling, pain, tingling, discomfort, ...

  5. Performance of an Otto cycle motor with natural gas direct injection; Desempenho de um motor ciclo Otto com injecao direta de gas natural

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, Cleiton Rubens Formiga


    A Otto cycle engine with natural gas direct injection, during the inlet stroke, was submitted to runs with full power in a Foucaut dynamometer. The results obtained show a increase in the volumetric efficiency of the engine with natural gas direct injection when compared with natural gas injection applied in the inlet manifold, upstream of the throttle butterfly. In the conversion to natural gas direct injection, the technical characteristics were not changed. A kit for natural gas direct injection, with electronic management was located on the cylinder head of the test engine. Maintaining the pressure constant in the natural gas fuel line, using a reduction valve, the mass of fuel injected into the cylinder was regulated, varying the opening time of the solenoid valve fuel injector. Engine performance data is compared, emphasizing the factors that contribute to this increase in relative volumetric efficiency. Modifications are made to maximize the power of the engine with natural gas direct injection. (author)

  6. Filter-based control of particulate matter from a lean gasoline direct injection engine

    Energy Technology Data Exchange (ETDEWEB)

    Parks, II, James E [ORNL; Lewis Sr, Samuel Arthur [ORNL; DeBusk, Melanie Moses [ORNL; Prikhodko, Vitaly Y [ORNL; Storey, John Morse [ORNL


    New regulations requiring increases in vehicle fuel economy are challenging automotive manufacturers to identify fuel-efficient engines for future vehicles. Lean gasoline direct injection (GDI) engines offer significant increases in fuel efficiency over the more common stoichiometric GDI engines already in the marketplace. However, particulate matter (PM) emissions from lean GDI engines, particularly during stratified combustion modes, are problematic for lean GDI technology to meet U.S. Environmental Protection Agency Tier 3 and other future emission regulations. As such, the control of lean GDI PM with wall-flow filters, referred to as gasoline particulate filter (GPF) technology, is of interest. Since lean GDI PM chemistry and morphology differ from diesel PM (where more filtration experience exists), the functionality of GPFs needs to be studied to determine the operating conditions suitable for efficient PM removal. In addition, lean GDI engine exhaust temperatures are generally higher than diesel engines which results in more continuous regeneration of the GPF and less presence of the soot cake layer common to diesel particulate filters. Since the soot layer improves filtration efficiency, this distinction is important to consider. Research on the emission control of PM from a lean GDI engine with a GPF was conducted on an engine dynamometer. PM, after dilution, was characterized with membrane filters, organic vs. elemental carbon characterization, and size distribution techniques at various steady state engine speed and load points. The engine was operated in three primary combustion modes: stoichiometric, lean homogeneous, and lean stratified. In addition, rich combustion was utilized to simulate PM from engine operation during active regeneration of lean NOx control technologies. High (>95%) PM filtration efficiencies were observed over a wide range of conditions; however, some PM was observed to slip through the GPF at high speed and load conditions. The

  7. Onset of liquid droplet entrainment on a direct vessel injection system for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Han-sol; Lee, Jae-Young [Handong Global University, Pohang (Korea, Republic of); Kim, Jong-Rok; Euh, Dong-Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)


    In this research, a series of visualization works was conducted to understand droplet entrainment of the flow pattern generated in direct vessel injection system(DVI) of Korea nuclear power plant, APR 1400. In the emergency situation of a nuclear power plant, reliability of DVI cooling can be an important issue. It is known that, the amount and the rate of entrainment during the DVI cooling process can significantly affect the total heat removal. To visualize the film Reynolds number closely related with onset of droplet entrainment induced by falling film flow and lateral air flow in a small gap, confocal chromatic sensing method for measuring accurately film thickness and depth averaging particle image velocimetry for film velocity were used. The results have been post processed 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. To visualize the droplet entrainment induced by falling film flow and lateral air flow in a small gap, shadowgraph method with CCD camera (2200fps, 1280 pixel X 800 pixel, ) on coated plate with super water-repellent agent was used. The results have been post processed using 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. By adopting both super hydrophobic coating method and shadowgraph method, entrainment in a narrow gap was successfully visualized that has rarely performed before and meaningful results for DVI system research fields have been made.

  8. Measurement of elemental speciation by liquid chromatography -- inductively coupled plasma mass spectrometry (LC-ICP-MS) with the direct injection nebulizer (DIN)

    Energy Technology Data Exchange (ETDEWEB)

    Shum, S.


    This thesis is divided into 4 parts: elemental speciation, speciation of mercury and lead compounds by microbore column LC-ICP-MS with direct injection nebulization, spatially resolved measurements of size and velocity distributions of aerosol droplets from a direct injection nebulizer, and elemental speciation by anion exchange and size exclusion chromatography with detection by ICP-MS with direct injection nebulization. Tabs, figs, refs.

  9. Analysis of mixture formation of direct injection gasoline engine; Tonai funsha gasoline engine no kongoki keisei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kano, M.; Saito, K.; Basaki, M. [Nippon Soken, Inc., Tokyo (Japan); Matsushita, S.; Gono, T. [Toyota Motor Corp., Aichi (Japan)


    On direct injection gasoline engine, in order to achieve good stratified combustion, the extremely advanced control of air-fuel mixture is required. For this purpose, the method of diagnosing the quality of the state of mixture formation in combustion chambers becomes necessary. In this research, the state of air-fuel mixture in the combustion chamber of a TOYOTA D-4 was analyzed in space and time by visualization, A/F multi-point measurement and A/F high response measurement, thus the effects that injection timing, swirl and fuel pressure exerted to mixture formation were elucidated. 3 refs., 17 figs., 1 tab.

  10. Control of homogeneous charge compression ignition combustion in a two-cylinder gasoline direct injection engine with negative valve overlap

    Institute of Scientific and Technical Information of China (English)

    WANG Zhi; WANG Jianxin; SHUAI Shijin; MA Qingjun; TIAN Guohong


    Homogeneous charge compression ignition(HCCI) has challenges in ignition timing control,combustion rate control,and operating range extension.In this paper,HCCI combustion was studied in a two-cylinder gasoline direct injection (GDI) engine with negative valve overlap (NVO).A two-stage gasoline direct injection strategy combined with negative valve overlap was used to control mixture formation and combustion.The gasoline engine could be operated in HCCI combustion mode at a speed range of 800-2 200 r/min and load,indicated mean effective pressure (IMEP) range of 0.1-0.53 MPa.The engine fuel consumption 4× 10-5 without soot emission.The effect of different injection strategies on HCCI combustion was studied.The experimental results indicated that the coefficient of variation of the engine cycle decreased by using NVO with two-stage direct injection;the ignition timing and combustion rate could be controlled;and the operational range of HCCI combustion could be extended.

  11. Exploring Blueberry Aroma Complexity by Chromatographic and Direct-Injection Spectrometric Techniques

    Directory of Open Access Journals (Sweden)

    Brian Farneti


    pull of VOCs, for the most aldehydes, alcohols, terpenoids, and esters that can be used as putative biomarkers to rapidly evaluate the blueberry aroma variations related to ripening and/or senescence as well as to genetic background differences. Moreover, the obtained results demonstrated the complementarity between chromatographic and direct-injection mass spectrometric techniques to study the blueberry aroma.

  12. Exploring Blueberry Aroma Complexity by Chromatographic and Direct-Injection Spectrometric Techniques. (United States)

    Farneti, Brian; Khomenko, Iuliia; Grisenti, Marcella; Ajelli, Matteo; Betta, Emanuela; Algarra, Alberto Alarcon; Cappellin, Luca; Aprea, Eugenio; Gasperi, Flavia; Biasioli, Franco; Giongo, Lara


    , and esters that can be used as putative biomarkers to rapidly evaluate the blueberry aroma variations related to ripening and/or senescence as well as to genetic background differences. Moreover, the obtained results demonstrated the complementarity between chromatographic and direct-injection mass spectrometric techniques to study the blueberry aroma.

  13. Performance evaluation of common rail direct injection (CRDI engine fuelled with Uppage Oil Methyl Ester (UOME

    Directory of Open Access Journals (Sweden)

    D.N. Basavarajappa


    Full Text Available For economic and social development of any country energy is one of the most essential requirements. Continuously increasing price of crude petroleum fuels in the present days coupled with alarming emissions and stringent emission regulations has led to growing attention towards use of alternative fuels like vegetable oils, alcoholic and gaseous fuels for diesel engine applications. Use of such fuels can ease the burden on the economy by curtailing the fuel imports. Diesel engines are highly efficient and the main problems associated with them is their high smoke and NOx emissions. Hence there is an urgent need to promote the use of alternative fuels in place of high speed diesel (HSD as substitute. India has a large agriculture base that can be used as a feed stock to obtain newer fuel which is renewable and sustainable. Accordingly Uppage oil methyl ester (UOME biodiesel was selected as an alternative fuel. Use of biodiesels in diesel engines fitted with mechanical fuel injection systems has limitation on the injector opening pressure (300 bar. CRDI system can overcome this drawback by injecting fuel at very high pressures (1500-2500 bar and is most suitable for biodiesel fuels which are high viscous. This paper presents the performance and emission characteristics of a CRDI diesel engine fuelled with UOME biodiesel at different injection timings and injection pressures. From the experimental evidence it was revealed that UOME biodiesel yielded overall better performance with reduced emissions at retarded injection timing of -10° BTDC in CRDI mode of engine operation.

  14. Direct-acting mutagenicity of extracts of coal burning-derived particulates and contribution of nitropolycyclic aromatic hydrocarbons. (United States)

    Taga, Rina; Tang, Ning; Hattori, Tetsuyuki; Tamura, Kenji; Sakai, Shigekatsu; Toriba, Akira; Kizu, Ryoichi; Hayakawa, Kazuichi


    Benzene-ethanol extracts from particulates produced by coal burning were separated into four fractions by silica-gel column chromatography using n-hexane (240 ml), n-hexane-dichloromethane (3:1, v/v) (200 ml), dichloromethane (200 ml) and methanol (450 ml), as the corresponding eluents. The mutagenicity of each fraction was assayed by the Ames test using the Salmonellatyphimurium YG1024 strain. The nitropolycyclic aromatic hydrocarbons (NPAHs) of each fraction were assayed by high-performance liquid chromatography with chemiluminescence detection. The highest activity was observed in the n-hexane-dichloromethane fraction (Fr. 2). The mutagenic contribution of this fraction was 69.9% of the total of the four fractions. Ten of 11 NPAHs detected were in Fr. 2 and one (1-nitropyrene) was most concentrated in Fr. 3. Among the NPAHs examined, 3-nitrobenzanthrone made the largest mutagenic contribution. This is the first report of detection of 3-nitrobenzanthrone in coal burning-derived particulates.

  15. Direct injection into the IsoDAR Cyclotron using a RFQ (United States)

    Axani, Spencer; IsoDAR Collaboration


    Beginning in the 1970s, the use of Radio Frequency Quadrupoles (RFQs) has been pervasive in linear accelerators in order to accelerate, bunch, and separate ion species. Current research suggests this may be an ideal way to inject a low energy H2+ beam axially into a cyclotron. The IsoDAR (Isotope Decay At Rest) experiment aims to implement this injection system in order to achieve higher Low Energy Beam Transport (LEBT) efficiencies and ultimately construct a novel compact neutrino factory to test the hypothesis of sterile neutrinos. This talk will focus on the research and development needed to implement a RFQ into the IsoDAR experiment.

  16. Analyse de la sensibilité aux paramètres gazoles d'un moteur diesel d'automobile à injection directe Small Direct Injection Diesel Engine Sensitivity to the Diesel Fuel Characteristics

    Directory of Open Access Journals (Sweden)

    Montagne X.


    Full Text Available L'étude présentée a été réalisée dans le cadre du GMCL (Groupement Moteur Carburant Lubrifiant, organisme qui réunit des constructeurs d'automobiles, des raffineurs et des additiveurs, avec l'objectif d'examiner la sensibilité d'un moteur Diesel à injection directe d'automobile aux paramètres du gazole. Les partenaires de cette étude sont Elf, IFP, Octel, PSA, Renault et Total. Parmi les solutions technologiques permettant de disposer de convertisseurs d'énergie assurant de faibles niveaux d'émissions de polluants et de consommation, le moteur Diesel se place naturellement en bonne position. Dans ce contexte, on enregistre aujourd'hui l'émergence du moteur Diesel à injection directe pour les véhicules légers en raison de ses performances, notamment en regard de la consommation. Toutefois, cette technologie nécessite une technique d'injection performante, associée à la gestion électronique, demande de l'EGR et un catalyseur d'oxydation afin de régler les problèmes d'émissions polluantes et sonores. Il est donc de première importance de cerner avec précision la sensibilité du moteur Diesel à injection directe aux paramètres carburants afin de tirer le meilleur profit de cette technologie. À partir d'un ensemble de gazoles formulés pour faire varier la composition chimique, l'indice de cétane et la densité, un moteur Audi à injection directe de type 1Z a été testé au banc, dans des conditions standard de réglage (avance à l'injection et taux de gaz recyclés. Cet ensemble de résultats a ainsi permis de démontrer que l'accroissement de l'indice de cétane, la réduction de la densité et de la teneur en polyaromatiques ont une influence positive sensible sur les émissions de CO, d'hydrocarbures imbrûlés, des VOF. En ce qui concerne les émissions de particules, l'indice de cétane semble avoir une influence négative sur la fraction sèche dans certaines conditions. De plus, il apparaît que les

  17. Scald Burns (United States)

    Safety Tips & Info Scald Burns Thousands of scald burns occur annually, and ALL are preventable! The two high-risk populations are children under the age ... the single most important factor in preventing scald burns. Increased awareness is the key to scald prevention! ...

  18. Separation of inverse spin hall effect and spin rectification effect by inverting spin injection direction in NiFe/ta bilayers film (United States)

    Wang, Qiuru; Zhang, Wanli; Peng, Bin; Zhang, Wenxu


    The inverse spin Hall effect (ISHE) has been detected and separated from spin rectification effect (SRE) by inverting spin injection direction in metallic system. This work is based on the relation between the two effects and the spin injection direction: the sign of VISHE changes because of the reversing direction of spin injection while the VSRE is independent on it. According to the different voltage signals before and after the spin injection inverted, the pure VISHE and VSRE are calculated by utilizing the method of addition and subtraction. The signals can be separated in a wide range of frequency and power.

  19. Injeção subconjuntival de soro autógeno no tratamento de queimadura ocular por álcali em coelhos Subconjunctival injection of autogenous blood in the treatment of ocular alcali burn in rabbits

    Directory of Open Access Journals (Sweden)

    Marcela Colussi Cypel


    Full Text Available OBJETIVO: Estudar a ação da injeção subconjuntival de soro autógeno na evolução das complicações, após queimadura ocular grave por álcali induzida experimentalmente em coelhos. MÉTODOS: Foram utilizados trinta olhos de coelhos da raça Nova Zelândia, divididos em dois grupos, de 15 coelhos cada, ambos submetidos à queimadura grave por álcali. Em 15 olhos (grupo tratado, efetuamos, imediatamente após a queimadura, injeção de soro autógeno subconjuntival. Os resultados foram avaliados e comparados logo após a queimadura e nos dias 1, 3, 7, 15 e 30 por meio de ectoscopia biomicroscopia ocular. RESULTADOS: O grupo tratado apresentou melhor resposta de reepitelização da córnea, na fase inicial do processo do que o grupo controle (grupo sem soro autógeno, diferença esta estaticamente significante, assim como resultado final com um menor número de complicações. CONCLUSÃO: Os resultados obtidos neste estudo experimental sugerem que soro autógeno pode ter efeito no processo de cicatrização dos olhos após queimadura alcalina, diminuindo complicações tardias e melhorando o prognóstico quanto à estabilidade do processo inflamatório cicatricial.PURPOSE: To determine the activity of subconjunctival injection of autogenous serum in the treatment of ocular alkali burn induced experimentally in rabbits. METHODS: Thirty eyes of 30 New Zeland albino rabbits were divided into two groups of 15 and submitted to ocular alkali burn. One group (treated group received immediately after the alkali burn a subconjunctival injection of autogenous serum. The results were compared and recorded immediately after the alkali burn and on days 1, 3, 7, 15, and 30 by external ocular examination and manual portable slit lamp. RESULTS: The treated group presented a better reepithelialization of the cornea than the control group, in the beginning of the process, with a statistically significant difference; and a final result with less complications

  20. Directing Parthenogenetic Stem Cells Differentiate into Adipocytes for Engineering Injectable Adipose Tissue

    Directory of Open Access Journals (Sweden)

    Wei Liu


    Full Text Available The selection of appropriate seed cells is crucial for adipose tissue engineering. Here, we reported the stepwise induction of parthenogenetic embryonic stem cells (pESCs to differentiate into adipogenic cells and its application in engineering injectable adipose tissue with Pluronic F-127. pESCs had pluripotent differentiation capacity and could form teratomas that include the three primary germ layers. Cells that migrated from the embryoid bodies (EBs were selectively separated and expanded to obtain embryonic mesenchymal stem cells (eMSCs. The eMSCs exhibited similar cell surface marker expression profiles with bone morrow mesenchymal stem cells (BMSCs and had multipotent differentiation capacity. Under the induction of dexamethasone, indomethacin, and insulin, eMSCs could differentiate into adipogenic cells with increased expression of adipose-specific genes and oil droplet depositions within the cytoplasm. To evaluate their suitability as seed cells for adipose tissue engineering, the CM-Dil labelled adipogenic cells derived from eMSCs were seeded into Pluronic F-127 hydrogel and injected subcutaneously into nude mice. Four weeks after injection, glistering and semitransparent constructs formed in the subcutaneous site. Histological observations demonstrated that new adipose tissue was successfully fabricated in the specimen by the labelled cells. The results of the current study indicated that pESCs have great potential in the fabrication of injectable adipose tissue.


    Gas chromatography coupled to Fourier-transform infrared spectroscopy (GC/FT-IR) is rapidly becoming an accepted analytical technique complementary to GC/mass spectroscopy for identifying organic compounds in mixtures at low to moderate concentrations. irect aqueous injection (DA...

  2. The influence of fuel injection and heat release on bulk flow structures in a direct-injection, swirl-supported diesel engine (United States)

    Sterl, Andreas; van Oldenborgh, Geert Jan; Hazeleger, Wilco; Burgers, Gerrit


    Particle image velocimetry is applied to measure the vertical (r z) plane flow structures in a light-duty direct-injection diesel engine with a realistic piston geometry. The measurements are corrected for optical distortions due to the curved piston bowl walls and the cylindrical liner. Mean flow fields are presented and contrasted for operation both with and without fuel injection and combustion. For operation with combustion, the two-dimensional divergence of the measured mean velocity fields is employed as a qualitative indicator of the locations of mean heat release. In agreement with numerical simulations, dual-vortex, vertical plane mean flow structures that may enhance mixing rates are formed approximately mid-way through the combustion event. Late in the cycle a toroidal vortex forms outside the bowl mouth. Imaging studies suggest that soot and partially oxidized fuel trapped within this vortex are slow to mix with surrounding fluid; moreover, the vortex impedes mixing of fluid exiting the bowl with air within the squish volume.

  3. Performance evaluation of common rail direct injection (CRDI engine fuelled with Uppage Oil Methyl Ester (UOME

    Directory of Open Access Journals (Sweden)

    D.N. Basavarajappa


    Full Text Available For economic and social development of any country energy is one of the most essential requirements. Continuously increasing price of crude petroleum fuels in the present days coupled with alarming emissions and stringent emission regulations has led to growing attention towards use of alternative fuels like vegetable oils, alcoholic and gaseous fuels for diesel engine applications. Use of such fuels can ease the burden on the economy by curtailing the fuel imports. Diesel engines are highly efficient and the main problems associated with them is their high smoke and NOx emissions.  Hence there is an urgent need to promote the use of alternative fuels in place of high speed diesel (HSD as substitute. India has a large agriculture base that can be used as a feed stock to obtain newer fuel which is renewable and sustainable. Accordingly Uppage oil methyl ester (UOME biodiesel was selected as an alternative fuel. Use of biodiesels in diesel engines fitted with mechanical fuel injection systems has limitation on the injector opening pressure (300 bar. CRDI system can overcome this drawback by injecting fuel at very high pressures (1500-2500 bar and is most suitable for biodiesel fuels which are high viscous. This paper presents the performance and emission characteristics of a CRDI diesel engine fuelled with UOME biodiesel at different injection timings and injection pressures. From the experimental evidence it was revealed that UOME biodiesel yielded overall better performance with reduced emissions at retarded injection timing of -10° BTDC in CRDI mode of engine operation.

  4. Environmental Pollution Assessment of Different Diesel Injector Location Of Direct-Injection Diesel Engines: Theoretical Study

    Directory of Open Access Journals (Sweden)

    Eyad S.M. Abu-Nameh


    Full Text Available An Analytical investigation on the effect of injector location of a four-stroke DI diesel engine on its pollutants’ emissions was carried out under different injector locations ranging from central to peripheral at different engine speeds ranging from 1000 rpm to 3000 rpm. The simulation results clearly indicated the advantages and disadvantages of the central location over the peripheral one. It revealed that near central location gave less carbon dioxide, smoke level and particulate matter on one hand, and higher levels of NOx, cylinder temperature and pressure (hence increased the mechanical and thermal stresses on the other hand. Further, near central location resulted in more rapid rate of burning and less duration of combustion and rapid rate of NOx formation per crank angle.

  5. The effect of injection pressure on spread of the jet, formation of the mixture and engine parameters of a direct injection Diesel engine. Einfluss des Einspritzdruckes auf Strahlausbreitung, Gemischbildung und Motorkennwerte eines direkt einspritzenden Dieselmotors

    Energy Technology Data Exchange (ETDEWEB)

    Binder, K.


    By increasing the injection pressure, the air/fuel ratio in the fuel jet is raised. The increased air supply in the injected jet, together with a drop spectrum displaced in the direction of smaller fuel drops leads to a quicker evaporation of the fuel. As the injection retardation is simultaneously reduced, one can achieve lower emission of nitrogen oxide without disadvantage in the fuel consumption. (orig./HW).

  6. CFD Studies of Combustion in Direct Injection Single Cylinder Diesel Engine Using Non-Premixed Combustion Model

    Directory of Open Access Journals (Sweden)

    S Gavudhama Karunanidhi


    Full Text Available In this study the simulation process of non-premixed combustion in a direct injection single cylinder diesel engine has been described. Direct injection diesel engines are used both in heavy duty vehicles and light duty vehicles. The fuel is injected directly into the combustion chamber. The fuel mixes with the high pressure air in the combustion chamber and combustion occurs. Due to the non-premixed nature of the combustion occurring in such engines, non-premixed combustion model of ANSYS FLUENT 14.5 can be used to simulate the combustion process. A 4-stroke diesel engine corresponds to one fuel injector hole without considering valves was modeled and combustion simulation process was studied. Here two types of combustion chambers were compared. Combustion studies of both chambers:- shallow depth and hemispherical combustion chambers were carried out. Emission characteristics of both combustion chambers had also been carried out. The obtained results are compared. It has been found that hemispherical combustion chamber is more efficient as it produces higher pressure and temperature compared to that of shallow depth combustion chamber. As the temperature increases the formation of NOx emissions and soot formation also get increased.

  7. Replacement of diesel oil by hydrous ethyl alcohol in direct burning: a comparison; Substituicao do oleo diesel por alcool etilico hidratado na queima direta: uma comparacao

    Energy Technology Data Exchange (ETDEWEB)

    Perez, Edgar Paz; Carvalho Junior, Joao Andrade de; Carrocci, Luiz Roberto [Universidade Estadual Paulista (FEG/UNESP), Guaratingueta, SP (Brazil). Fac. de Engenharia], Emails:,,


    This article presents a study of the substitution of diesel fuel by ethyl alcohol in direct burning. The investigation is concentrated in the physical-chemical properties of the fuels, the combustion thermodynamics, the atomization, and the pollutants formation. Results show that hydrated ethyl alcohol can be an attractive alternative for diesel fuel, mainly by the benefits in the combustion process and the pollutants formation. Nevertheless, care must be taken in the substitution to prevent losses by evaporation, fire risks and material damage by corrosion. (author)

  8. Experimental and theoretical study on spray behaviors of modified bio-ethanol fuel employing direct injection system

    Directory of Open Access Journals (Sweden)

    Ghahremani Amirreza


    Full Text Available One of the key solutions to improve engine performance and reduce exhaust emissions of internal combustion engines is direct injection of bio-fuels. A new modified bio-ethanol is produced to be substituted by fossil fuels in gasoline direct injection engines. The key advantages of modified bio-ethanol fuel as an alternative fuel are higher octane number and oxygen content, a long-chain hydro-carbon fuel, and lower emissions compared to fossil fuels. In the present study spray properties of a modified bio-ethanol and its atomization behaviors have been studied experimentally and theoretically. Based on atomization physics of droplets dimensional analysis has been performed to develop a new non-dimensional number namely atomization index. This number determines the atomization level of the spray. Applying quasi-steady jet theory, air entrainment and fuel-air mixing studies have been performed. The spray atomization behaviors such as atomization index number, Ohnesorge number, and Sauter mean diameter have been investigated employing atomization model. The influences of injection and ambient conditions on spray properties of different blends of modified bio-ethanol and gasoline fuels have been investigated performing high-speed visualization technique. Results indicate that decreasing the difference of injection and ambient pressures increases spray cone angle and projected area, and decreases spray tip penetration length. As expected, increasing injection pressure improves atomization behaviors of the spray. Increasing percentage of modified bio-ethanol in the blend, increases spray tip penetration and decreases the projected area as well.

  9. Burn Rehabilitation

    Directory of Open Access Journals (Sweden)

    Koray Aydemir


    Full Text Available Burn injuries are important in terms of causing serious disability and threatening life. With the establishment of modern burn treatment units and advances in acute care management contributed to a reduced mortality rate over the last decades. As a result of improved outcome, more attention has to be given to a comprehensive burn rehabilitation program. Burn rehabilitation is a process that starts from day of admission and continues for months or sometimes years after the initial event. The term ‘burn rehabilitation’ incorporates the physical, physiological and social aspects of care. Burns can leave a patient with severely debilitating and deforming contractures, which can lead to significant disability when left untreated. Burn rehabilitation aims to prevent the possible complications, minimalize joint contractures and deformities, increase range of motion, control hypertrophic scarring, achieve the best possible functional capacity and to regain the patients vocational and recreational activities. (Journal of the Turkish Society Intensive Care 2011; 9 Suppl: 70-7

  10. Effect of hydrogen on ethanol-biodiesel blend on performance and emission characteristics of a direct injection diesel engine. (United States)

    Parthasarathy, M; Isaac JoshuaRamesh Lalvani, J; Dhinesh, B; Annamalai, K


    Environment issue is a principle driving force which has led to a considerable effort to develop and introduce alternative fuels for transportation. India has large potential for production of biofuels like biodiesel from vegetable seeds. Use of biodiesel namely, tamanu methyl ester (TME) in unmodified diesel engines leads to low thermal Efficiency and high smoke emission. To encounter this problem hydrogen was inducted by a port fueled injection system. Hydrogen is considered to be low polluting fuel and is the most promising among alternative fuel. Its clean burning characteristic and better performance attract more interest compared to other fuels. It was more active in reducing smoke emission in biodiesel. A main drawback with hydrogen fuel is the increased NOx emission. To reduce NOx emission, TME-ethanol blends were used in various proportions. After a keen study, it was observed that ethanol can be blended with biodiesel up to 30% in unmodified diesel engine. The present work deals with the experimental study of performance and emission characteristic of the DI diesel engine using hydrogen and TME-ethanol blends. Hydrogen and TME-ethanol blend was used to improve the brake thermal efficiency and reduction in CO, NOx and smoke emissions. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Optical chaos synchronization and encrypted communications of VCSEL by direct optical injection (United States)

    Hosomi, Naohito; Sasaki, Wakao


    In this work, we propose electro-optical nonlinear delayed feedback systems (NDFS) for optical secure communications using VCSEL for the first time. Its optical output can perform more sensitive chaotic dynamics by varying only a few mA of injection current range resulting in very significant charges of VCSEL's operation conditions from threshold to maximum rating. This enables us to vary chaotic output dynamically by a slight difference of initial values in NDFS. We have proposed a chaos synchronization system using two identical NDFS's of VCSEL, and realized chaos synchronization by optical injection. As a result of experiment the correlation coefficient up to about 0.88 was obtained. Moreover, by varying the delay time and feedback gain in the parameters of NDFSs, we have confirmed that the variations of these parameters may affect variations of correlation.

  12. An Analysis of Direct-injection spark-ignition (DISI) soot morphology

    Energy Technology Data Exchange (ETDEWEB)

    Barone, Teresa L [ORNL; Storey, John Morse [ORNL; Youngquist, Adam D [ORNL; Szybist, James P [ORNL


    We have characterized particle emissions produced by a 4-cylinder, 2.0 L DISI engine using transmission electron microscopy (TEM) and image analysis. Analyses of soot morphology provide insight to particle formation mechanisms and strategies for prevention. Particle emissions generated by two fueling strategies were investigated, early injection and injection modified for low particle number concentration emissions. A blend of 20% ethanol and 80% emissions certification gasoline was used for the study given the likelihood of increased ethanol content in widely available fuel. In total, about 200 particles and 3000 primary soot spherules were individually measured. For the fuel injection strategy which produced low particle number concentration emissions, we found a prevalence of single solid sub-25 nm particles and fractal-like aggregates. The modal diameter of single solid particles and aggregate primary particles was between 10 and 15 nm. Solid particles as small as 6 nm were present. Although nanoparticle aggregates had fractal-like morphology similar to diesel soot, the average primary particle diameter per aggregate had a much wider range that spanned from 7 to 60 nm. For the early fuel injection strategy, liquid droplets were prevalent, and the modal average primary particle diameter was between 20 and 25 nm. The presence of liquid droplets may have been the result of unburned fuel and/or lubricating oil originating from fuel impingement on the piston or cylinder wall; the larger modal aggregate primary particle diameter suggests greater fuel-rich zones in-cylinder than for the low particle number concentration point. However, both conditions produced aggregates with a wide range of primary particle diameters, which indicates heterogeneous fuel and air mixing.

  13. Successful endovascular treatment of a hemodialysis graft pseudoaneurysm by covered stent and direct percutaneous thrombin injection.

    LENUS (Irish Health Repository)

    Keeling, Aoife N


    Vascular access for hemodialysis remains a challenge for nephrologists, vascular surgeons, and interventional radiologists alike. Arteriovenous fistula and synthetic grafts remain the access of choice for long-term hemodialysis; however, they are subject to complications from infection and repeated needle cannulation. Pseudoaneurysms are an increasingly recognized adverse event. At present, there are many minimally invasive methods to repair these wall defects. We present a graft pseudoaneurysm, which required a combination of endovascular stent graft placement and percutaneous thrombin injection for successful occlusion.

  14. FITL: Extending LLVM for the Translation of Fault-Injection Directives

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seyong [ORNL; Vetter, Jeffrey S [ORNL


    The frequency of hardware errors in HPC systems continues to grow as system designs evolve toward exascale. Tolerating these errors efficiently and effectively will require software-based resilience solutions. With this requirement in mind, recent research has increasingly employed LLVM-based tools to simulate transient hardware faults in order to study the resilience characteristics of specific applications. However, such tools require researchers to configure their experiments at the level of the LLVM intermediate representation (LLVM IR) rather than at the source level of the applications under study. In this paper, we present FITL (Fault-Injection Toolkit for LLVM), a set of LLVM extensions to which it is straightforward to translate source-level pragmas that specify fault injection. While we have designed FITL not to be tied to any particular compiler front end or high-level language, we also describe how we have extended our OpenARC compiler to translate a novel set of fault-injection pragmas for C to FITL. Finally, we present several resilience studies we have conducted using FITL, including a comparison with a source-level fault injector we have built as part of OpenARC.

  15. Investigations of soot formation in an optically accessible gasoline direct injection engine by means of laser-induced incandescence (LII) (United States)

    Hertler, D.; Stirn, R.; Arndt, S.; Grzeszik, R.; Dreizler, A.


    This study presents the results of laser-induced incandescence (LII) measurements in an optically accessible gasoline direct injection engine. The focus was to evaluate LII as a particle measurement technique which is able to provide a deeper understanding of the underlying reaction and formation processes of soot in order to optimize the injection system to reduce exhaust gas emissions. A comparison of time-resolved LII, based on the model described by Michelsen, with an Engine Exhaust Particle Sizer (EEPS) was performed. In this context, the air-fuel ratio, the injection pressure and the injection timing have been varied while applying the measurement techniques in the exhaust system. In case of a variation of the air-fuel ratio, two-dimensional LII has been performed in the combustion chamber additionally. For each measurement, the Filter Smoke Number (FSN) was taken into account as well. Finally, a good agreement of the different techniques was achieved. Moreover, we found that by combining time-resolved LII and EEPS a differentiation of primary particles and agglomerates is possible. Consequently, a determination of the processes in the combustion chamber and agglomeration in the exhaust gas is feasible.

  16. Three-dimensional analysis of internal flow characteristics in the injection nozzle tip of direct-injection diesel engines; Sanjigen suchi kaiseki ni yoru DI diesel kikan no nenryo funsha nozzle nai ryudo tokusei no kaimei

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, H.; Matsui, Y.; Kimura, S. [Nissan Motor Co. Ltd. Tokyo (Japan)


    To reduce the exhaust emissions and fuel consumption of direct-injection diesel engines, it is essential to optimize the fuel injection equipment closely related to combustion and emission characteristics. In this study, three-dimensional computation has been applied to investigate the effects of the injection nozzle specifications (e.g., sac volume, round shape at the inlet of the nozzle hole) and needle tip deviation on internal flow characteristics. The computational results revealed that the effects of the nozzle specifications and needle tip deviation with a smaller needle lift on internal flow characteristics and a general approach to optimize the injection nozzle specifications were obtained. 3 refs., 10 figs., 1 tab.

  17. Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons. (United States)

    Yang, Xiao-Yang; Igarashi, Kazuhiko; Tang, Ning; Lin, Jin-Ming; Wang, Wei; Kameda, Takayuki; Toriba, Akira; Hayakawa, Kazuichi


    Particulates exhausted from two types of diesel engines (DEPs), burning-derived particulates from three types of coal (CBPs) and burning-derived particulates from three types of wood (WBPs) were separated into four fractions by silica-gel column chromatography using n-hexane, n-hexane-dichloromethane (3:1, v/v), dichloromethane and methanol, as the corresponding eluents. The indirect-acting mutagenicity of each fraction was assayed by the Ames test using the Salmonella typhimurium TA100 strain with S9 mix and the direct-acting mutagenicity was assayed using the S. typhimurium TA98 strain without S9 mix. The polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (NPAHs) of each fraction were determined by high-performance liquid chromatography (HPLC). Both direct- and indirect-acting of mutagenicities were the highest in samples of DEPs. The contributions of PAHs in samples of WBPs and NPAHs in DEPs were the largest, respectively. Copyright 2009 Elsevier B.V. All rights reserved.

  18. Assessing Rates of Global Warming Emissions from Port- Fuel Injection and Gasoline Direct Injection Engines in Light-Duty Passenger Vehicles (United States)

    Short, D.; , D., Vi; Durbin, T.; Karavalakis, G.; Asa-Awuku, A. A.


    Passenger vehicles are known emitters of climate warming pollutants. CO2 from automobile emissions are an anthropogenic greenhouse gas (GHG) and a large contributor to global warming. Worldwide, CO2 emissions from passenger vehicles are responsible for 11% of the total CO2 emissions inventory. Black Carbon (BC), another common vehicular emission, may be the second largest contributor to global warming (after CO2). Currently, 52% of BC emissions in the U.S are from the transportation sector, with ~10% originating from passenger vehicles. The share of pollutants from passenger gasoline vehicles is becoming larger due to the reduction of BC from diesel vehicles. Currently, the majority of gasoline passenger vehicles in the United States have port- fuel injection (PFI) engines. Gasoline direct injection (GDI) engines have increased fuel economy compared to the PFI engine. GDI vehicles are predicted to dominate the U.S. passenger vehicle market in the coming years. The method of gasoline injection into the combustion chamber is the primary difference between these two technologies, which can significantly impact primary emissions from light-duty vehicles (LDV). Our study will measure LDV climate warming emissions and assess the impact on climate due to the change in U.S vehicle technologies. Vehicles were tested on a light- duty chassis dynamometer for emissions of CO2, methane (CH4), and BC. These emissions were measured on F3ederal and California transient test cycles and at steady-state speeds. Vehicles used a gasoline blend of 10% by volume ethanol (E10). E10 fuel is now found in 95% of gasoline stations in the U.S. Data is presented from one GDI and one PFI vehicle. The 2012 Kia Optima utilizes GDI technology and has a large market share of the total GDI vehicles produced in the U.S. In addition, The 2012 Toyota Camry, equipped with a PFI engine, was the most popular vehicle model sold in the U.S. in 2012. Methane emissions were ~50% lower for the GDI technology

  19. TiO{sub 2} anatase films obtained by direct liquid injection atomic layer deposition at low temperature

    Energy Technology Data Exchange (ETDEWEB)

    Avril, L., E-mail: [Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS-Université de Bourgogne, 9 Av. A. Savary, BP 47 870, F-21078 Dijon Cedex (France); Reymond-Laruinaz, S. [Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS-Université de Bourgogne, 9 Av. A. Savary, BP 47 870, F-21078 Dijon Cedex (France); Decams, J.M. [Annealsys, rue de la Vieille Poste, 34055 Montpellier Cedex 1 (France); Bruyère, S.; Potin, V.; Lucas, M.C. Marco de; Imhoff, L. [Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS-Université de Bourgogne, 9 Av. A. Savary, BP 47 870, F-21078 Dijon Cedex (France)


    TiO{sub 2} thin films were grown by direct liquid injection atomic layer deposition (DLI-ALD) with infrared rapid thermal heating using titanium tetraisopropoxide and water as precursors. This titanium tetraisopropoxide/water process exhibited a growth rate of 0.018 nm/cycle in a self-limited ALD growth mode at 280 °C. Scanning electron microscopy and atomic force microscopy analyses have shown a smooth surface with a low roughness. XPS results demonstrated that the films were pure and close to the TiO{sub 2} stoichiometric composition in depth. Raman spectroscopy revealed that the films were crystallized to the anatase structure in the as-deposited state at low temperature without necessity of high temperature annealing. Results obtained demonstrate that the liquid injection ALD is an efficient method of elaborating titanium oxide films using titanium tetraisopropoxide as precursor.

  20. Studies of the Combustion Process with Simultaneous Formaldehyde and OH PLIF in a Direct-Injected HCCI Engine (United States)

    Richter, Mattias; Collin, Robert; Nygren, Jenny; Aldén, Marcus; Hildingsson, Leif; Johansson, Bengt

    This paper presents simultaneous laser based measurements of formaldehyde and OH-radical distributions in a 0.5 liter optical HCCI engine with direct injection. Formaldehyde is formed as an intermediate species when combusting hydrocarbons. The formation occurs through low temperature reactions in an early phase of the combustion process. Later in the process formaldehyde is being consumed. Formaldehyde is, therefore, used as indicator of the first stage of combustion and a marker of zones with low-temperature reactions. The OH radical is formed as an intermediate during the high temperature reactions, and is used as a marker of zones where the combustion is ongoing. The purpose of the investigation was to study how the combustion process is affected by the change in homogeneity that arises from early and late injection, respectively. The measurement technique used was planar laser-induced fluorescence where formaldehyde was excited at 355nm and OH at 283nm.

  1. Estimation of operational parameters for a direct injection turbocharged spark ignition engine by using regression analysis and artificial neural network

    Directory of Open Access Journals (Sweden)

    Tosun Erdi


    Full Text Available This study was aimed at estimating the variation of several engine control parameters within the rotational speed-load map, using regression analysis and artificial neural network techniques. Duration of injection, specific fuel consumption, exhaust gas at turbine inlet, and within the catalytic converter brick were chosen as the output parameters for the models, while engine speed and brake mean effective pressure were selected as independent variables for prediction. Measurements were performed on a turbocharged direct injection spark ignition engine fueled with gasoline. A three-layer feed-forward structure and back-propagation algorithm was used for training the artificial neural network. It was concluded that this technique is capable of predicting engine parameters with better accuracy than linear and non-linear regression techniques.

  2. Numerical Simulations of Two-Phase Reacting Flow in a Single-Element Lean Direct Injection (LDI) Combustor Using NCC (United States)

    Liu, Nan-Suey; Shih, Tsan-Hsing; Wey, C. Thomas


    A series of numerical simulations of Jet-A spray reacting flow in a single-element lean direct injection (LDI) combustor have been conducted by using the National Combustion Code (NCC). The simulations have been carried out using the time filtered Navier-Stokes (TFNS) approach ranging from the steady Reynolds-averaged Navier-Stokes (RANS), unsteady RANS (URANS), to the dynamic flow structure simulation (DFS). The sub-grid model employed for turbulent mixing and combustion includes the well-mixed model, the linear eddy mixing (LEM) model, and the filtered mass density function (FDF/PDF) model. The starting condition of the injected liquid spray is specified via empirical droplet size correlation, and a five-species single-step global reduced mechanism is employed for fuel chemistry. All the calculations use the same grid whose resolution is of the RANS type. Comparisons of results from various models are presented.

  3. Penetration of natural gas in industrial processes for direct burning: the case of ceramics, cement and glass industries; Penetracao do gas natural em processos industriais de queima direta: caso das industrias ceramica, cimento e vidro

    Energy Technology Data Exchange (ETDEWEB)

    Berni, Mauro Donizeti; Leite, Alvaro A. Furtado [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Dorileo, Ivo Leandro [Universidade Federal do Mato Grosso (NIEPE/UFMT), Cuiaba, MT (Brazil). Nucleo Interdisciplinar de Estudos em Planejamento Energetico; Bajay, Sergio Valdir [Universidade estadual de Campinas (FEM/UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica. Dept. de Energia], e-mail:


    Industrial sector can use the natural gas (NG) as raw material, as fuel and in co-generation. The NG as fuel is used, predominantly, to produce heat in the Brazilian industries. That rate, both main forms of industrial use of the NG are its direct burning in kilns - when the direct contact is had with the product - and the supply of process heat through boilers, for instance. Direct burning is used in the ceramic, cement and glass industries. This work discuss the penetration opportunity of the NG in the direct burning regarding the fuel oil and other energy that it can substitute, the environmental effects and the co-generation possibilities in each one of the analyzed industrial blanches in this work. (author)

  4. Immune tolerance induction using fetal directed placental injection in rodent models: a murine model.

    Directory of Open Access Journals (Sweden)

    Kei Takahashi

    Full Text Available Induction of the immune response is a major problem in replacement therapies for inherited protein deficiencies. Tolerance created in utero can facilitate postnatal treatment. In this study, we aimed to induce immune tolerance towards a foreign protein with early gestational cell transplantation into the chorionic villi under ultrasound guidance in the murine model.Pregnant C57BL/6 (B6 mice on day 10 of gestation were anesthetized and imaged by high resolution ultrasound. Murine embryos and their placenta were positioned to get a clear view in B-mode with power mode of the labyrinth, which is the equivalent of chorionic villi in the human. Bone marrow cells (BMCs from B6-Green Fluorescence Protein (B6GFP transgenic mice were injected into the fetal side of the placenta which includes the labyrinth with glass microcapillary pipettes. Each fetal mouse received 2 x 105 viable GFP-BMCs. After birth, we evaluated the humoral and cell-mediated immune response against GFP.Bone marrow transfer into fetal side of placenta efficiently distributed donor cells to the fetal mice. The survival rate of this procedure was 13.5%(5 out of 37. Successful engraftment of the B6-GFP donor skin grafts was observed in all recipient (5 out of 5 mice 6 weeks after birth. Induction of anti-GFP antibodies was completely inhibited. Cytotoxic immune reactivity of thymic cells against cells harboring GFP was suppressed by ELISPOT assay.In this study, we utilized early gestational placental injection targeting the murine fetus, to transfer donor cells carrying a foreign protein into the fetal circulation. This approach is sufficient to induce both humoral and cell-mediated immune tolerance against the foreign protein.

  5. Combined Flux Observer With Signal Injection Enhancement for Wide Speed Range Sensorless Direct Torque Control of IPMSM Drives

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Andreescu, G.-D.; Pitic, C.I.;


    This paper proposes a motion-sensorless control system using direct torque control with space vector modulation for interior permanent magnet synchronous motor (IPMSM) drives, for wide speed range operation, including standstill. A novel stator flux observer with variable structure uses a combined...... voltage-current model with PI compensator for low-speed operations. As speed increases, the observer switches gradually to a PI compensated closed-loop voltage model, which is solely used at high speeds. High-frequency rotating-voltage injection with a single D-module bandpass vector filter and a phase...

  6. Lube-oil dilution of gasoline direct-injection engines with ethanol fuels; Schmieroelverduennung von direkteinspritzenden Ottomotoren unter Kaltstartrandbedingungen

    Energy Technology Data Exchange (ETDEWEB)

    Kuepper, Carsten; Pischinger, Stefan [RWTH Aachen Univ. (Germany). Lehrstuhl fuer Verbrennungskraftmaschinen (VKA); Artmann, Chrsitina; Rabl, Hans-Peter [Hochschule Regensburg (Germany). Labor fuer Verbrennungsmotoren und Abgasnachbehandlung


    Ethanol fuel mixtures account for the majority of biofuels used worldwide. However, their properties make these fuels more difficult to use in cold conditions and especially when starting a cold engine. As part of the FVV research project 'Lubricant Dilution with Ethanol Fuels under Cold Start Conditions', the Institute for Combustion Engines (VKA) at RWTH Aachen University and the Combustion Engines and Emission Control Laboratory at Regensburg University of Applied Sciences have investigated the influence of the ethanol content in fuels on the dilution of the lubricating oil in modern direct-injection gasoline engines. (orig.)

  7. EGR and fuel sulphur influences on particle size distributions from a heavy duty direct injection diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, J.D.; Wedekind, B.; Widdicombe, K.A. [Ricardo Consulting Engineers Ltd., Shoreham-by-Sea (United Kingdom)


    Diesel exhaust particle emissions were determined from the EGR system of a heavy duty direct injection engine. Both mass and number weighted particle size distribution analyses were undertaken. Measurements were acquired from the inlet manifold at two levels of EGR with two levels of fuel sulphur. An increase in EGR level was found to increase particle numbers but had little influence on the mass weighted size distribution of the exhaust aerosol. Particle mass emissions were increased slightly. An increase in fuel sulphur influenced both the number and mass weighted size distributions measured. Particle mass emissions were minimally affected. (author)

  8. Performance and efficiency evaluation and heat release study of a direct-injection stratified-charge rotary engine (United States)

    Nguyen, H. L.; Addy, H. E.; Bond, T. H.; Lee, C. M.; Chun, K. S.


    A computer simulation which models engine performance of the Direct Injection Stratified Charge (DISC) rotary engines was used to study the effect of variations in engine design and operating parameters on engine performance and efficiency of an Outboard Marine Corporation (OMC) experimental rotary combustion engine. Engine pressure data were used in a heat release analysis to study the effects of heat transfer, leakage, and crevice flows. Predicted engine data were compared with experimental test data over a range of engine speeds and loads. An examination of methods to improve the performance of the rotary engine using advanced heat engine concepts such as faster combustion, reduced leakage, and turbocharging is also presented.

  9. Study of nozzle deposit formation mechanism for direct injection gasoline engines; Chokufun gasoline engine yo nozzle no deposit seisei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, M.; Saito, A. [Toyota Central Research and Development Labs., Inc., Aichi (Japan); Matsushita, S. [Toyota Motor Corp., Aichi (Japan); Shibata, H. [Nippon Soken, Inc., Tokyo (Japan); Niwa, Y. [Denso Corp., Aichi (Japan)


    Nozzles in fuel injectors for direct injection gasoline engines are exposed to high temperature combustion gases and soot. In such a rigorous environment, it is a fear that fuel flow rate changes in injectors by deposit formation on nozzles. Fundamental factors of nozzle deposit formation were investigated through injector bench tests and engine dynamometer tests. Deposit formation processes were observed by SEM through engine dynamometer tests. The investigation results reveal nozzle deposit formation mechanism and how to suppress the deposit. 4 refs., 8 figs., 3 tabs.

  10. Analysis and Verification of Direct Vessel Injection Line Break event tree for AP1000 reactor with TRACE code

    Energy Technology Data Exchange (ETDEWEB)

    Queral, C.; Montero-Mayorga, J.; Gonzalez-Cadelo, J.


    The AP1000 PRA thermal hydraulic simulations were performed with MAAP code, which allows simulating sequences with low computational efforts. On the other hand, the use of best estimate codes allows verifying PRA results as well as obtaining a greater knowledge of the phenomenology of such sequences. The initiating event with the greatest contribution to core damage is Direct Vessel Injection Line Break (DVILB). This paper presents a review of DVILB sequences of AP1000 with TRACE code for verifying sequences previously analyzed by Westinghouse with MAAP code. The sequences which configure the DVILB event tree during short term have been simulated. The results obtained confirm the ones obtained in AP1000 PRA.

  11. Numerical investigation of liver radioembolization via computational particle-hemodynamics: The role of the microcatheter distal direction and microsphere injection point and velocity. (United States)

    Aramburu, Jorge; Antón, Raúl; Rivas, Alejandro; Ramos, Juan Carlos; Sangro, Bruno; Bilbao, José Ignacio


    Liver radioembolization is a treatment option for patients with primary and secondary liver cancer. The procedure consists of injecting radiation-emitting microspheres via an intra-arterially placed microcatheter, enabling the deposition of the microspheres in the tumoral bed. The microcatheter location and the particle injection rate are determined during a pretreatment work-up. The purpose of this study was to numerically study the effects of the injection characteristics during the first stage of microsphere travel through the bloodstream in a patient-specific hepatic artery (i.e., the near-tip particle-hemodynamics and the segment-to-segment particle distribution). Specifically, the influence of the distal direction of an end-hole microcatheter and particle injection point and velocity were analyzed. Results showed that the procedure targeted the right lobe when injecting from two of the three injection points under study and the remaining injection point primarily targeted the left lobe. Changes in microcatheter direction and injection velocity resulted in an absolute difference in exiting particle percentage for a given liver segment of up to 20% and 30%, respectively. It can be concluded that even though microcatheter placement is presumably reproduced in the treatment session relative to the pretreatment angiography, the treatment may result in undesired segment-to-segment particle distribution and therefore undesired treatment outcomes due to modifications of any of the parameters studied, i.e., microcatheter direction and particle injection point and velocity.

  12. Multi-Dimensional Modeling of the Effects of Air Jet and Split Injection on Combustion and Emission of DirectInjection Diesel Engine

    Directory of Open Access Journals (Sweden)

    Mehdi Mansury


    Full Text Available One of the most important problems in reducing the emissions of diesel engines is to exchange between the oxides of nitrogen and soot emissions. Fuel multiple injection and air injection into combustion chamber are among the most powerful tools to concurrent reduction of these two emissions. In this research, the effect of multiple injection and air injection on combustion and emission parameters has been studied by AVL fire computational fluid dynamic software. Six states of base and modified combustion chamber have been studied in two different injection patterns including 90 (25 10 and 75 (25 25 mods. Results show that concurrent applying of both multiple injection and air injection methods has resulted in simultaneous reduction of oxide nitrogen and soot pollutants and a negligible loss is seen in the operational parameters of engine. Compression between six studied cases show that the 90 (25 10 mode of injection with modified combustion chamber is the optimum mode by decreasing of soot and oxides of nitrogen emissions about 29% and 20% respectively and 6% indicated power loss in compression to the base combustion chamber and single injection mode. The obtained results from the computational fluid dynamic code have been compared with the existing results in the technical literature and show acceptable behavior.

  13. Bright hybrid white light-emitting quantum dot device with direct charge injection into quantum dot (United States)

    Cao, Jin; Xie, Jing-Wei; Wei, Xiang; Zhou, Jie; Chen, Chao-Ping; Wang, Zi-Xing; Jhun, Chulgyu


    A bright white quantum dot light-emitting device (white-QLED) with 4-[4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl]-2- [3-(tri-phenylen-2-yl)phen-3-yl]quinazoline deposited on a thin film of mixed green/red-QDs as a bilayer emitter is fabricated. The optimized white-QLED exhibits a turn-on voltage of 3.2 V and a maximum brightness of 3660 cd/m2@8 V with the Commission Internationale de l’Eclairage (CIE) chromaticity in the region of white light. The ultra-thin layer of QDs is proved to be critical for the white light generation in the devices. Excitation mechanism in the white-QLEDs is investigated by the detailed analyses of electroluminescence (EL) spectral and the fluorescence lifetime of QDs. The results show that charge injection is a dominant mechanism of excitation in the white-QLED. Project supported by the National Natural Science Foundation of China (Grant No. 21302122) and the Science and Technology Commission of Shanghai Municipality, China (Grant No. 13ZR1416600).

  14. 76 FR 79051 - Airworthiness Directives; Lycoming Engines, Fuel Injected Reciprocating Engines (United States)


    ...-AD; Amendment 39-16894; AD 2011-26-04] RIN 2120-AA64 Airworthiness Directives; Lycoming Engines, Fuel... AD to prevent failure of the fuel injector fuel lines that would allow fuel to spray into the engine... response, any AD made applicable to TCM engines with externally mounted fuel injector lines, would have...

  15. Suppressing the relaxation oscillation noise of injection-locked WRC-FPLD for directly modulated OFDM transmission. (United States)

    Cheng, Min-Chi; Chi, Yu-Chieh; Li, Yi-Cheng; Tsai, Cheng-Ting; Lin, Gong-Ru


    By up-shifting the relaxation oscillation peak and suppressing its relative intensity noise in a weak-resonant-cavity Fabry-Perot laser diode (WRC-FPLD) under intense injection-locking, the directly modulated transmission of optical 16 quadrature amplitude modulation (QAM) orthogonal frequency division multiplexing (OFDM) data-stream is demonstrated. The total bit rate of up to 20 Gbit/s within 5-GHz bandwidth is achieved by using the OFDM subcarrier pre-leveling technique. With increasing the injection-locking power from -12 to -3 dBm, the effective reduction on threshold current of the WRC-FPLD significantly shifts its relaxation oscillation frequency from 5 to 7.5 GHz. This concurrently induces an up-shift of the peak relative intensity noise (RIN) of the WRC-FPLD, and effectively suppresses the background RIN level to -104 dBc/Hz within the OFDM band between 3 and 6 GHz. The enhanced signal-to-noise ratio from 16 to 20 dB leads to a significant reduction of bit-error-rate (BER) of the back-to-back transmitted 16-QAM-OFDM data from 1.3 × 10(-3) to 5 × 10(-5), which slightly degrades to 1.1 × 10(-4) after 25-km single-mode fiber (SMF) transmission. However, the enlarged injection-locking power from -12 to -3 dBm inevitably declines the modulation throughput and increases its negative throughput slope from -0.8 to -1.9 dBm/GHz. After pre-leveling the peak amplitude of the OFDM subcarriers to compensate the throughput degradation of the directly modulated WRC-FPLD, the BER under 25-km SMF transmission can be further improved to 3 × 10(-5) under a receiving power of -3 dBm.

  16. Influence of Injector Location on Part-Load Performance Characteristics of Natural Gas Direct-Injection in a Spark Ignition Engine

    Energy Technology Data Exchange (ETDEWEB)

    Sevik, James [Argonne National Lab. (ANL), Argonne, IL (United States); Pamminger, Michael [Argonne National Lab. (ANL), Argonne, IL (United States); Wallner, Thomas [Argonne National Lab. (ANL), Argonne, IL (United States); Scarcelli, Riccardo [Argonne National Lab. (ANL), Argonne, IL (United States); Boyer, Brad [Ford Motor Co., Detroit, MI (United States); Wooldridge, Steven [Ford Motor Co., Detroit, MI (United States); Hall, Carrie [Illinois Inst. of Technology, Chicago, IL (United States); Miers, Scott [Michigan Technological Univ., Houghton, MI (United States)


    Interest in natural gas as an alternative fuel source to petroleum fuels for light-duty vehicle applications has increased due to its domestic availability and stable price compared to gasoline. With its higher hydrogen-to-carbon ratio, natural gas has the potential to reduce engine out carbon dioxide emissions, which has shown to be a strong greenhouse gas contributor. For part-load conditions, the lower flame speeds of natural gas can lead to an increased duration in the inflammation process with traditional port-injection. Direct-injection of natural gas can increase in-cylinder turbulence and has the potential to reduce problems typically associated with port-injection of natural gas, such as lower flame speeds and poor dilution tolerance. A study was designed and executed to investigate the effects of direct-injection of natural gas at part-load conditions. Steady-state tests were performed on a single-cylinder research engine representative of current gasoline direct-injection engines. Tests were performed with direct-injection in the central and side location. The start of injection was varied under stoichiometric conditions in order to study the effects on the mixture formation process. In addition, exhaust gas recirculation was introduced at select conditions in order to investigate the dilution tolerance. Relevant combustion metrics were then analyzed for each scenario. Experimental results suggest that regardless of the injector location, varying the start of injection has a strong impact on the mixture formation process. Delaying the start of injection from 300 to 120°CA BTDC can reduce the early flame development process by nearly 15°CA. While injecting into the cylinder after the intake valves have closed has shown to produce the fastest combustion process, this does not necessarily lead to the highest efficiency, due to increases in pumping and wall heat losses. When comparing the two injection configurations, the side location shows the best

  17. Modeling of fault activation and seismicity by injection directly into a fault zone associated with hydraulic fracturing of shale-gas reservoirs (United States)

    LBNL, in consultation with the EPA, expanded upon a previous study by injecting directly into a 3D representation of a hypothetical fault zone located in the geologic units between the shale-gas reservoir and the drinking water aquifer.

  18. Demountable direct injection high efficiency nebulizer for inductively coupled plasma mass spectrometry (United States)

    Montaser, Akbar; Westphal, Craig S.; Kahen, Kaveh; Rutkowski, William F.; Acon, Billy W.


    A nebulizer adapted for adjusting a position of a capillary tube contained within the nebulizer is provided. The nebulizer includes an elongated tubular shell having a gas input port and a gas output port, a capillary adjustment adapter for displacing the capillary tube in a lateral direction via a rotational force, and a connector for connecting the elongated tubular shell, the capillary adjustment adapter and the capillary tube.

  19. [Reconstruction of facial burn sequelae]. (United States)

    Foyatier, J L; Comparin, J P; Boulos, J P; Bichet, J C; Jacquin, F


    The deep burns of the face can lead to horrible scars functionally and aesthetically. Treatment of these scars need several surgical interventions frequently and during many years. In our region we deal with this type of wounds as team work, multidisciplinary approach carrying out many process starting by emergency treatment of acute burns till the social rehabilitation. The expansion technique was great help in improving the shape of scars, by using the expanding skin as full thickness grafts. Reconstruction of the anatomical units and application of aesthetic techniques (like rhinoplasty, lifting, tattooing and autologous fat injections) participate equally in improving the quality of results. Many examples of treatments of burns scars are shown.

  20. Application of micro injection pump in liquid resuscitation during burn shock in children%微量泵在小儿烧伤休克期液体复苏中的应用

    Institute of Scientific and Technical Information of China (English)

    肖玉秋; 郑一双; 邢楠


    目的:探讨微量注射泵(以下简称微量泵)在小儿重度烧伤休克期液体复苏中的应用.方法:回顾2010年10月至2012年5月我科收治的77例中重度烧伤(TBSA>10%)患儿中,在休克期液体复苏时使用微量泵的41例作为试验组,在休克液体复苏中使用常规输液器进行液体复苏的36例作为对照组,比较两组患者的护理工作情况.结果:使用微量泵的试验组的BD留置针穿刺次数平均(1.34±0.57)次,数量少于常规输液的对照组的平均(2.36±0.83)次;试验组护士调节输液滴数的平均次数(1.22±1.03)次,少于对照组的(6.25±1.69)次.结论:中重度烧伤患儿休克期液体复苏时使用微量泵能减少留置针的穿刺,减轻护士工作量.%Objective To investigate the application of micro injection pump (hereinafter referred as micro pump) in liquid resuscitation during burn shock in children. Methods The data of 77 children with severe burn (TBSA > 10%) who had been hospitalized during the period of October 2010 to May 2012 were reviewed. 41 children who used micro pump in liquid resuscitation during burn shock were assigned to the study group, while 36 children who used conventional infusion pump fluid resuscitation were allocated to control group. Results The frequency of indwelling needle puncture was smaller in in the study group than in the control group [ (1.34 ± 0.57) times vs. (2.36 ± 0.83) times]. The frequecny of adjusting the drip speed by nurses was smaller in the study group than in the control group [(1.22 ± 1.03) times vs. (6.25 ± 1.69) times]. Conclusions Micro injection pump in liquid resuscitation during burn shock in children with moderate to severe burn can reduce frequency of indwelling needle puncture and relieve the workload in nurses.

  1. New methodology for in-cylinder pressure analysis in direct injection diesel engines—application to combustion noise (United States)

    Payri, F.; Broatch, A.; Tormos, B.; Marant, V.


    The objective of this paper is to present a new methodology for the analysis of in-cylinder pressure in direct injection (DI) diesel engines. Indeed, for some applications, the traditional study of total pressure is shown to be insufficient and the proposed technique is intended to be an alternative and more efficient tool, since it may provide a better understanding of the physical mechanisms. The main idea is to decompose the in-cylinder pressure evolution according to three phenomena taking place during diesel engine operation: pseudo-motored, combustion and resonance excitation. In order to validate this new method, it is applied to combustion noise analysis. Actually, the combustion process in DI diesel engines may be considered as an important source of noise, and the traditional approach is mainly based on the interpretation of objective overall spectral levels of both in-cylinder pressure and radiated noise, obtained from Fourier analysis. However, this approach has been shown unable to describe all the relevant aspects of the problem, whereas the results obtained from the proposed decomposition technique exhibit a fair qualitative correlation between in-cylinder pressure and combustion noise issues. Further development of this approach could provide a useful tool for the development of optimal injection strategies fulfilling not only performance considerations but also sound quality requirements for combustion noise in DI diesel engines.

  2. Direct and comprehensive analysis of ginsenosides and diterpene alkaloids in Shenfu injection by combinatory liquid chromatography-mass spectrometric techniques. (United States)

    Yang, Hua; Liu, Lei; Gao, Wen; Liu, Ke; Qi, Lian-Wen; Li, Ping


    Shenfu injection (SFI) is a widely used Chinese herbal formulation for cardiac diseases prepared from red ginseng and processed aconite root. Clinical observations and pharmacological effects on SFI have been well investigated. Chemical analysis and quality control studies of this formulation, however, are relatively limited, especially regarding toxic aconite alkaloids. In this work, a high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-QTOF MS) method was applied to comprehensive analysis of constituents in SFI. Highly sensitive MS allows direct analysis of injections without additional sample pretreatment required. Using diagnostic ions and fragmentation rules, we identified 23 trace diterpene alkaloids, nineteen ginseng saponins, one panaxytriol, and one 5-hydroxymethylfurfural in SFI. A LC-MS method with selected ion monitoring was then used to quantify 24 major alkaloids and ginsenosides. The method was validated in terms of linearity, accuracy and precision. Especially, the limits of quantification were low to 0.4-18ng/mL for diterpene alkaloids. The total concentrations of saponins and alkaloids were about 676-742μg/mL and 3-7μg/mL in five batches of SFI samples, respectively. Finally, cosine ratio and euclidean distance were introduced to evaluate the batch-to-batch reproducibility of SFI samples, and the results demonstrated high quality consistency. Global identification and quantification of complex constituents based on LC-MS promises wide applications in quality control and batch monitoring for herbal products.

  3. Rapid determination of piracetam in human plasma and cerebrospinal fluid by micellar electrokinetic chromatography with sample direct injection. (United States)

    Yeh, Hsin-Hua; Yang, Yuan-Han; Ko, Ju-Yun; Chen, Su-Hwei


    A simple micellar electrokinetic chromatography (MEKC) method with UV detection at 200 nm for analysis of piracetam in plasma and in cerebrospinal fluid (CSF) by direct injection without any sample pretreatment is described. The separation of piracetam from biological matrix was performed at 25 degrees C using a background electrolyte consisting of Tris buffer with sodium dodecyl sulfate (SDS) as the electrolyte solution. Several parameters affecting the separation of the drug from biological matrix were studied, including the pH and concentrations of the Tris buffer and SDS. Under optimal MEKC condition, good separation with high efficiency and short analyses time is achieved. Using imidazole as an internal standard (IS), the linear ranges of the method for the determination of piracetam in plasma and in CSF were all between 5 and 500 microg/mL; the detection limit of the drug in plasma and in CSF (signal-to-noise ratio=3; injection 0.5 psi, 5s) was 1.0 microg/mL. The applicability of the proposed method for determination of piracetam in plasma and CSF collected after intravenous administration of 3g piracetam every 6h and oral administration 1.2g every 6h in encephalopathy patients with aphasia was demonstrated.

  4. Determination of pesticides and pesticide degradates in filtered water by direct aqueous-injection liquid chromatography-tandem mass spectrometry (United States)

    Sandstrom, Mark W.; Kanagy, Leslie K.; Anderson, Cyrissa A.; Kanagy, Christopher J.


    A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of 229 pesticides compounds (113 pesticides and 116 pesticide degradates) in filtered water samples from stream and groundwater sites. The pesticides represent a broad range of chemical classes and were selected based on criteria such as current-use intensity, probability of occurrence in streams and groundwater, and toxicity to humans or aquatic organisms. More than half of the analytes are pesticide degradates. The method involves direct injection of a 100-microliter (μL) sample onto the LC-MS/MS without any sample preparation other than filtration. Samples are analyzed with two injections, one in electrospray ionization (ESI) positive mode and one in ESI negative mode, using dynamic multiple reaction monitoring (MRM) conditions, with two MRM transitions for each analyte. The LC-MS/MS instrument parameters were optimized for highest sensitivity for the most analytes. This report describes the analytical method and presents characteristics of the method validation including bias and variability, detection levels, and holding-time studies.

  5. Fast online emission monitoring of volatile organic compounds (VOC) in wastewater and product streams (using stripping with direct steam injection). (United States)

    Schocker, Alexander; Lissner, Bert


    Open-loop stripping analysis (also referred to as dynamic headspace) is a very flexible and robust technology for online monitoring of volatile organic compounds in wastewater or coolant. However, the quality and reliability of the analytical results depend strongly on the temperature during the stripping process. Hence, the careful and constant heating of the liquid phase inside the stripping column is a critical parameter. In addition, this stripping at high temperatures extends the spectrum of traceable organics to less volatile and more polar compounds with detection limits down to the ppm-level. This paper presents a novel and promising approach for fast, efficient, and constant heating by the direct injection of process steam into the strip medium. The performance of the system is demonstrated for temperatures up to 75 °C and traces of various hydrocarbons in water (e.g., tetrahydrofuran, methanol, 1-propanol, n-butanol, ethylbenzene).

  6. Integration of FTTH and GI-POF in-house networks based on injection locking and direct-detection techniques. (United States)

    Peng, Hsiao-Chun; Lu, Hai-Han; Li, Chung-Yi; Su, Heng-Sheng; Hsu, Chin-Tai


    An integration of fiber-to-the-home (FTTH) and graded-index plastic optical fiber (GI-POF) in-house networks based on injection-locked vertical cavity surface emitting lasers (VCSELs) and direct-detection technique is proposed and experimentally demonstrated. Sufficient low bit error rate (BER) values were obtained over a combination of 20-km single-mode fiber (SMF) and 50-m GI-POF links. Signal qualities satisfy the worldwide interoperability for microwave access (WiMAX) requirement with data signals of 20 Mbps/5.8 GHz and 70 Mbps/10 GHz, respectively. Since our proposed network does not use sophisticated and expensive RF devices in premises, it reveals a prominent one with simpler and more economic advantages. Our proposed architecture is suitable for the SMF-based primary and GI-POF-based in-house networks.

  7. Direct intramyocardial mesenchymal stromal cell injections in patients with severe refractory angina - one year follow-up

    DEFF Research Database (Denmark)

    Haack-Sørensen, Mandana; Friis, Tina; Mathiasen, Anders B;


    Aims: In patients with stable coronary artery disease (CAD) and refractory angina we performed direct intra-myocardial injections of autologous mesenchymal stromal cells (MSCs) and followed the safety and efficacy of the treatment for 12 months. Methods and Results: A total of 31 patients...... with stable CAD, moderate to severe angina, normal left ventricular ejection fraction and no further revascularization options, were included. Bone marrow MSCs were isolated and culture expanded for 6 - 8 weeks and then stimulated with vascular endothelial growth factor (VEGF) for one week.The 12 months...... follow-up demonstrated, that it was safe to culture expand MSCs and use the cells for clinical treatment. The patients maximal metabolic equivalent (MET) during exercise increased from 4.23 MET at baseline to 4.72 MET at 12 months follow-up (p...

  8. Direct current injection and thermocapillary flow for purification of aligned arrays of single-walled carbon nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Xu; Islam, Ahmad E.; Seabron, Eric; Dunham, Simon N.; Du, Frank; Lin, Jonathan; Wilson, William L.; Rogers, John A., E-mail: [Department of Materials Science and Engineering, Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States); Wahab, Muhammad A.; Alam, Muhammad A. [School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907 (United States); Li, Yuhang [Institute of Solid Mechanics, Beihang University, Beijing 100191 (China); Tomic, Bojan [Department of Electrical Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States); Huang, Jiyuan [Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States); Burns, Branden [Department of Physics, Purdue University, West Lafayette, Indiana 47907 (United States); Song, Jizhou [Department of Engineering Mechanics and Soft Matter Research Center, Zhejiang University, Hangzhou 310027 (China); Huang, Yonggang [Department of Civil and Environmental Engineering, Department of Mechanical Engineering, Center for Engineering and Health, and Skin Disease Research Center, Northwestern University, Evanston, Illinois 60208 (United States)


    Aligned arrays of semiconducting single-walled carbon nanotubes (s-SWNTs) represent ideal configurations for use of this class of material in high performance electronics. Development of means for removing the metallic SWNTs (m-SWNTs) in as-grown arrays represents an essential challenge. Here, we introduce a simple scheme that achieves this type of purification using direct, selective current injection through interdigitated electrodes into the m-SWNTs, to allow their complete removal using processes of thermocapillarity and dry etching. Experiments and numerical simulations establish the fundamental aspects that lead to selectivity in this process, thereby setting design rules for optimization. Single-step purification of arrays that include thousands of SWNTs demonstrates the effectiveness and simplicity of the procedures. The result is a practical route to large-area aligned arrays of purely s-SWNTs with low-cost experimental setups.

  9. Electrochemical Reduction of Carbon Dioxide to Methanol by Direct Injection of Electrons into Immobilized Enzymes on a Modified Electrode. (United States)

    Schlager, Stefanie; Dumitru, Liviu Mihai; Haberbauer, Marianne; Fuchsbauer, Anita; Neugebauer, Helmut; Hiemetsberger, Daniela; Wagner, Annika; Portenkirchner, Engelbert; Sariciftci, Niyazi Serdar


    We present results for direct bio-electrocatalytic reduction of CO2 to C1 products using electrodes with immobilized enzymes. Enzymatic reduction reactions are well known from biological systems where CO2 is selectively reduced to formate, formaldehyde, or methanol at room temperature and ambient pressure. In the past, the use of such enzymatic reductions for CO2 was limited due to the necessity of a sacrificial co-enzyme, such as nicotinamide adenine dinucleotide (NADH), to supply electrons and the hydrogen equivalent. The method reported here in this paper operates without the co-enzyme NADH by directly injecting electrons from electrodes into immobilized enzymes. We demonstrate the immobilization of formate, formaldehyde, and alcohol dehydrogenases on one-and-the-same electrode for direct CO2 reduction. Carbon felt is used as working electrode material. An alginate-silicate hybrid gel matrix is used for the immobilization of the enzymes on the electrode. Generation of methanol is observed for the six-electron reduction with Faradaic efficiencies of around 10%. This method of immobilization of enzymes on electrodes offers the opportunity for electrochemical application of enzymatic electrodes to many reactions in which a substitution of the expensive sacrificial co-enzyme NADH is desired.

  10. Room-temperature continuous-wave electrically injected InGaN-based laser directly grown on Si (United States)

    Sun, Yi; Zhou, Kun; Sun, Qian; Liu, Jianping; Feng, Meixin; Li, Zengcheng; Zhou, Yu; Zhang, Liqun; Li, Deyao; Zhang, Shuming; Ikeda, Masao; Liu, Sheng; Yang, Hui


    Silicon photonics would greatly benefit from efficient, visible on-chip light sources that are electrically driven at room temperature. To fully utilize the benefits of large-scale, low-cost manufacturing foundries, it is highly desirable to grow direct bandgap III-V semiconductor lasers directly on Si. Here, we report the demonstration of a blue-violet (413 nm) InGaN-based laser diode grown directly on Si that operates under continuous-wave current injection at room temperature, with a threshold current density of 4.7 kA cm-2. The heteroepitaxial growth of GaN on Si is confronted with a large mismatch in both the lattice constant and the coefficient of thermal expansion, often resulting in a high density of defects and even microcrack networks. By inserting an Al-composition step-graded AlN/AlGaN multilayer buffer between the Si and GaN, we have not only successfully eliminated crack formation, but also effectively reduced the dislocation density. The result is the realization of a blue-violet InGaN-based laser on Si.

  11. Experimental Studies of Diestrol-Micro Emulsion Fuel in a Direct Injection Compression Ignition Engine under Varying Injection Pressures and Timings (United States)

    Kannan, Gopal Radhakrishnan


    The research work on biodiesel becomes more attractive in the context of limited availability of petroleum fuels and rapid increase of harmful emissions from diesel engine using conventional fossil fuels. The present investigation has dealt with the influence of biodiesel-diesel-ethanol (diestrol) water micro emulsion fuel (B60D20E20M) on the performance, emission and combustion characteristics of a diesel engine under different injection pressure and timing. The results revealed that the maximum brake thermal efficiency of 32.4% was observed at an injection pressure of 260 bar and injection timing of 25.5°bTDC. In comparison with diesel, micro emulsion fuel showed reduction in carbon monoxide (CO) and total hydrocarbon (THC) by 40 and 24%, respectively. Further, micro emulsion fuel decreased nitric oxide (NO) emission and smoke emission by 7 and 20.7%, while the carbon dioxide (CO2) emission is similar to that of diesel.

  12. Direct visualization of neo-vessel formation following peripheral injection of bone marrow derived CD34+ cells in experimental myocardial damage. (United States)

    Ciulla, M M; Ferrero, S; Gianelli, U; Paliotti, R; Magrini, F; Braidotti, P


    The definitive fate of peripherally injected PKH26 labelled bone marrow mononuclear cells expressing the CD34+ antigen following experimental myocardial cryodamage in rats (n=10) has been examined by direct visualization on photoconverted light and electron microscopy images. One week after the injection in each rat of about 150,000 CD34+ cells early stage PKH26+ vascular structures were localized in the infarcted areas, suggesting that a potential benefit of this therapeutic approach consists in the regeneration of the vasculature.

  13. An Investigation on Injection Characteristics of Direct-Injected Heavy Duty Diesel Engine by Means of Multi-Zone Spray Modeling Étude sur les caractéristiques d’injection d’un moteur Diesel industriel à injection directe au moyen de la modélisation multi-zones de la pulvérisation

    Directory of Open Access Journals (Sweden)

    Javadi Rad G.


    Full Text Available The purpose of this study is to investigate the effect of injection parameters on a heavy duty diesel engine performance and emission characteristics. In order to analyze the injection and spray characteristics of diesel fuel with employing high-pressure common-rail injection system, the injection characteristics such as injection delay, injection duration, and injection rate and number of nozzle holes were investigated by using a quasi-dimensional model. In the present work, the variety of injection rate is performed at various injection parameters where as performance and emission of the engine will be simulated subsequently. Finally the best injection system for a high efficiency and low NOx emission heavy duty diesel engine was investigated. Le but de cette étude est d’étudier l’effet des paramètres d’injection sur les caractéristiques de performance et d’émissions d’un moteur Diesel industriel. Afin d’analyser les caractéristiques d’injection et de pulvérisation du gazole assurées par un système d’injection “common-rail” haute pression, les paramètres d’injection tels que le calage de l’injection, la durée de l’injection, le taux d’injection et le nombre de trous de l’injecteur ont été étudiés en utilisant un modèle quasi-dimensionnel. Dans l’étude présentée, les performances et les émissions du moteur sont simulées à différents taux d’injection en faisant varier des paramètres d’injection. Enfin, la meilleure définition du système d’injection a été recherchée pour obtenir un moteur Diesel industriel avec un haut rendement et de basses émissions de NOx.

  14. Multidimensional high-performance liquid chromatography on Pinkerton ISRP and RP18 columns: direct serum injection to quantify creatinine. (United States)

    Puhlmann, A; Dülffer, T; Kobold, U


    A two-dimensional high-performance liquid chromatographic method for the determination of creatinine with direct serum injection without sample pretreatment has been developed. The column-switching technique allowed a switch from columns packed with internal surface reversed-phase (ISRP) material to columns of almost any other material, even if the eluents necessary in a particular case do not appear to be directly compatible. A Pinkerton ISRP column, which stands out because of its very good stability when loaded with undiluted serum samples, was used as precolumn. The creatinine-containing fraction was switched to a reversed-phase Shandon RP18 column and was focused there by alteration of the eluent from pH 6.5 to phosphoric acid-ion-pair reagent. The separation occurs via a pH gradient, with ultraviolet detection at 234 nm. This method stands out particularly for its good long-term stability, simple sample handling without pretreatment, high selectivity, a broad linearity (0.3-30 mg/dl creatinine), good reproducibility (inter-assay coefficient of variation less than 3%) and high recovery (97-100%) relative to values obtained with gas chromatography-mass spectrometry.

  15. Development of a direct-injected natural gas engine system for heavy-duty vehicles: Final report phase 2

    Energy Technology Data Exchange (ETDEWEB)

    Cox, G.B.; DelVecchio, K.A.; Hays, W.J.; Hiltner, J.D.; Nagaraj, R.; Emmer, C.


    This report summarizes the results of Phase 2 of this contract. The authors completed four tasks under this phase of the subcontract. (1) They developed a computational fluid dynamics (CFD) model of a 3500 direct injected natural gas (DING) engine gas injection/combustion system and used it to identify DING ignition/combustion system improvements. The results were a 20% improvement in efficiency compared to Phase 1 testing. (2) The authors designed and procured the components for a 3126 DING engine (300 hp) and finished assembling it. During preliminary testing, the engine ran successfully at low loads for approximately 2 hours before injector tip and check failures terminated the test. The problems are solvable; however, this phase of the program was terminated. (3) They developed a Decision & Risk Analysis model to compare DING engine technology with various other engine technologies in a number of commercial applications. The model shows the most likely commercial applications for DING technology and can also be used to identify the sensitivity of variables that impact commercial viability. (4) MVE, Inc., completed a preliminary design concept study that examines the major design issues involved in making a reliable and durable 3,000 psi LNG pump. A primary concern is the life of pump seals and piston rings. Plans for the next phase of this program (Phase 3) have been put on indefinite hold. Caterpillar has decided not to fund further DING work at this time due to limited current market potential for the DING engine. However, based on results from this program, the authors believe that DI natural gas technology is viable for allowing a natural gas-fueled engine to achieve diesel power density and thermal efficiency for both the near and long terms.

  16. Ignition assist systems for direct-injected, diesel cycle, medium-duty alternative fuel engines: Final report phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Chan, A.K.


    This report is a summary of the results of Phase 1 of this contract. The objective was to evaluate the potential of assist technologies for direct-injected alternative fuel engines vs. glow plug ignition assist. The goal was to demonstrate the feasibility of an ignition system life of 10,000 hours and a system cost of less than 50% of the glow plug system, while meeting or exceeding the engine thermal efficiency obtained with the glow plug system. There were three tasks in Phase 1. Under Task 1, a comprehensive review of feasible ignition options for DING engines was completed. The most promising options are: (1) AC and the ''SmartFire'' spark, which are both long-duration, low-power (LDLP) spark systems; (2) the short-duration, high-power (SDHP) spark system; (3) the micropilot injection ignition; and (4) the stratified charge plasma ignition. Efforts concentrated on investigating the AC spark, SmartFire spark, and short-duration/high-power spark systems. Using proprietary pricing information, the authors predicted that the commercial costs for the AC spark, the short-duration/high-power spark and SmartFire spark systems will be comparable (if not less) to the glow plug system. Task 2 involved designing and performing bench tests to determine the criteria for the ignition system and the prototype spark plug for Task 3. The two most important design criteria are the high voltage output requirement of the ignition system and the minimum electrical insulation requirement for the spark plug. Under Task 3, all the necessary hardware for the one-cylinder engine test was designed. The hardware includes modified 3126 cylinder heads, specially designed prototype spark plugs, ignition system electronics, and parts for the system installation. Two 3126 cylinder heads and the SmartFire ignition system were procured, and testing will begin in Phase 2 of this subcontract.

  17. Mathematical study of methods to reduce emission of nitrogen oxides and particulate from a compression ignited, direct injection engine (United States)

    Gao, Zhiming


    A phenomenological model based on the multizone concept and a three-dimensional CFD model were used to predict the effect of engine modification on particulated and NOx emission from a compression ignited direct injection (CIDI) engine. The phenomenological model consisted of a spray model, an evaporation model, a heat release model, NOx formation, soot formation, and oxidation model, and can be used to predict the combustion process and pollutant emission in a CIDI diesel engine. The advantage of the multizone model over the 3-D CFD model is the small CPU and memory it requires for a simulation. In this study, the phenomenological model was used to investigate (1) the effect of increasing the intake-air O2 content on soot and NO x emission as a function of power level and wall temperature; and (2) the effect of exhaust gas recirculation (EGR) and split fuel injection on pollutant emission, and compare their soot penalty at a given NOx emission. The results indicate that EGR with a relatively low temperature can reduce NOx emission with a minimum penalty of soot particle emission. The use of EGR is promising for significantly reducing NOx emission with small or no penalty of soot particle emission. The effect of auxiliary gas injection (AGI) on diesel engine combustion and emission was studied using KIVA 3V, a multidimensional computation fluid dynamics code. AGI enhances the diesel combustion via mixing to reduce the emission of pollutants. The simulation of a high-speed gas jet model with a relatively coarse computational grids was described. The choice of turbulent length scale for optimum simulation suitability is dependent of local mesh grid. The results demonstrate that AGI creates a second-way flow in the cylinder, which improves the mixing of charge in the cylinder. The effect of AGI on combustion and flow movement is significant. The use of exhaust gas on the AGI can reduce soot emission, while NOx emission also can be decreased to some degree. To reduce

  18. Coupling sequential injection on-line preconcentration using a PTFE beads packed column to direct injection nebulization inductively coupled plasma mass spectrometry

    DEFF Research Database (Denmark)

    Wang, Jianhua; Hansen, Elo Harald


    An automated sequential injection on-line preconcentration procedure for trace metals by using a PTFE bead-packed microcolumn coupled to ICP-MS is described, and used for simultaneous analyses of cadmium and lead. In dilute nitric acid (0.5%, v/v), neutral complexes between the analytes and chela......An automated sequential injection on-line preconcentration procedure for trace metals by using a PTFE bead-packed microcolumn coupled to ICP-MS is described, and used for simultaneous analyses of cadmium and lead. In dilute nitric acid (0.5%, v/v), neutral complexes between the analytes...... and chelating reagent, diethyldithiophosphate (DDPA), are formed and adsorbed onto the surface of the PTFE beads. The adsorbed complexes are afterwards eluted with 20% nitric acid and the leading part of the eluate (40 mul) is stored in a sample loop (SL), the contents of which are subsequently transported, via...

  19. Multi-dimensional modelling of spray, in-cylinder air motion and fuel–air mixing in a direct-injection engine

    Indian Academy of Sciences (India)

    N Abani; S Bakshi; R V Ravikrishna


    In this work, three-dimensional fuel–air mixing inside a conventional spark ignition engine cylinder is simulated under direct injection conditions. The motivation is to explore retrofitting of conventional engines for direct injection to take advantage of low emissions and high thermal efficiency of the direct injection concept. Fuel–air mixing is studied at different loads by developing and applying a model based on the Lagrangian-drop and Eulerian-fluid (LDEF) procedure for modelling the two-phase flow. The Taylor Analogy Breakup (TAB) model for modelling the hollow cone spray and appropriate models for droplet impingement, drag and evaporation are used. Moving boundary algorithm and two-way interaction between both phases are implemented. Fuel injection timing and quantity is varied with load. Results show that near-stoichiometric fuel–air ratio region is observed at different locations depending on the load. The model developed serves to predict the fuel–air mixing spatially and temporally, and hence is a useful tool in design and optimization of direct injection engines with regards to injector and spark plug locations. Simulations over a range of speed and load indicate the need for a novel ignition strategy involving dual spark plugs and also provide guidelines in deciding spark plug locations.

  20. Rapid determination of benzodiazepines, zolpidem and their metabolites in urine using direct injection liquid chromatography-tandem mass spectrometry. (United States)

    Jeong, Yu-Dong; Kim, Min Kyung; Suh, Sung Ill; In, Moon Kyo; Kim, Jin Young; Paeng, Ki-Jung


    Benzodiazepines and zolpidem are generally prescribed as sedative, hypnotics, anxiolytics or anticonvulsants. These drugs, however, are frequently misused in drug-facilitated crime. Therefore, a rapid and simple liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed for identification and quantification of benzodiazepines, zolpidem and their metabolites in urine using deuterium labeled internal standards (IS). Urine samples (120 μL) mixed with 80 μL of the IS solution were centrifuged. An aliquot (5 μL) of the sample solution was directly injected into the LC-MS/MS system for analysis. The mobile phases consisted of water and acetonitrile containing 2mM ammonium trifluoroacetate and 0.2% acetic acid. The analytical column was a Zorbax SB-C18 (100 mm × 2.1 mm i.d., 3.5 μm, Agilent). The separation and detection of 18 analytes were achieved within 10 min. Calibration curves were linear over the concentration ranges of 0.5-20 ng/mL (zolpidem), 1.0-40 ng/mL (flurazepam and temazepam), 2.5-100 ng/mL (7-aminoclonazepam, 1-hydroxymidazolam, midazolam, flunitrazepam and alprazolam), 5.0-200 ng/mL (zolpidem phenyl-4-carboxylic acid, α-hydroxyalprazolam, oxazepam, nordiazepam, triazolam, diazepam and α-hydroxytriazolam), 10-400 ng/mL (lorazepam and desalkylflurazepam) and 10-100 ng/mL (N-desmethylflunitrazepam) with the coefficients of determination (r(2)) above 0.9971. The dilution integrity of the analytes was examined for supplementation of short linear range. Dilution precision and accuracy were tested using two, four and ten-folds dilutions and they ranged from 3.7 to 14.4% and -12.8 to 12.5%, respectively. The process efficiency for this method was 63.0-104.6%. Intra- and inter-day precisions were less than 11.8% and 9.1%, while intra- and inter-day accuracies were less than -10.0 to 8.2%, respectively. The lower limits of quantification were lower than 10 ng/mL for each analyte. The applicability of the developed method was successfully

  1. Burns (For Parents) (United States)

    ... Old Feeding Your 1- to 2-Year-Old Burns KidsHealth > For Parents > Burns A A A What's ... outlets, etc.) overexposure to the sun Types of Burns Burns are often categorized as first-, second-, or ...

  2. Effects of fresh lubricant oils on particle emissions emitted by a modern gasoline direct injection passenger car. (United States)

    Pirjola, Liisa; Karjalainen, Panu; Heikkilä, Juha; Saari, Sampo; Tzamkiozis, Theodoros; Ntziachristos, Leonidas; Kulmala, Kari; Keskinen, Jorma; Rönkkö, Topi


    Particle emissions from a modern turbocharged gasoline direct injection passenger car equipped with a three-way catalyst and an exhaust gas recirculation system were studied while the vehicle was running on low-sulfur gasoline and, consecutively, with five different lubrication oils. Exhaust particle number concentration, size distribution, and volatility were determined both at laboratory and on-road conditions. The results indicated that the choice of lubricant affected particle emissions both during the cold start and warm driving cycles. However, the contribution of engine oil depended on driving conditions being higher during acceleration and steady state driving than during deceleration. The highest emission factors were found with two oils that had the highest metal content. The results indicate that a 10% decrease in the Zn content of engine oils is linked with an 11-13% decrease to the nonvolatile particle number emissions in steady driving conditions and a 5% decrease over the New European Driving Cycle. The effect of lubricant on volatile particles was even higher, on the order of 20%.

  3. On Cyclic Variability in a Residual Effected HCCI Engine with Direct Gasoline Injection during Negative Valve Overlap

    Directory of Open Access Journals (Sweden)

    Jacek Hunicz


    Full Text Available This study contributes towards describing the nature of cycle-by-cycle variability in homogeneous charge compression ignition (HCCI engines. Experimental measurements were performed using a single cylinder research engine operated in the negative valve overlap (NVO mode and fuelled with direct gasoline injection. Both stoichiometric and lean mixtures were applied in order to distinguish between different exhaust-fuel reactions during the NVO period and their propagation into the main event combustion. The experimental results show that the mode of cycle-by-cycle variability depends on the NVO phenomena. Under stoichiometric mixture conditions, neither variability in the main event indicated mean effective pressure (IMEP nor the combustion timing was affected by the NVO phenomena; however, long period oscillations in IMEP were observed. In contrast, for lean mixture, where fuel oxidation during the NVO period took place, distinctive correlations between NVO phenomena and the main event combustion parameters were observed. A wavelet analysis revealed the presence of both long-term and short-term oscillations in IMEP, in accordance with the extent of NVO phenomena. Characteristic patterns in IMEP were recognized using an in-house algorithm.

  4. Analysis of Ignition Behavior in a Turbocharged Direct Injection Dual Fuel Engine Using Propane and Methane as Primary Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Polk, A. C.; Gibson, C. M.; Shoemaker, N. T.; Srinivasan, K. K.; Krishnan, S. R.


    This paper presents experimental analyses of the ignition delay (ID) behavior for diesel-ignited propane and diesel-ignited methane dual fuel combustion. Two sets of experiments were performed at a constant speed (1800 rev/min) using a 4-cylinder direct injection diesel engine with the stock ECU and a wastegated turbocharger. First, the effects of fuel-air equivalence ratios (© pilot ¼ 0.2-0.6 and © overall ¼ 0.2-0.9) on IDs were quantified. Second, the effects of gaseous fuel percent energy substitution (PES) and brake mean effective pressure (BMEP) (from 2.5 to 10 bar) on IDs were investigated. With constant © pilot (> 0.5), increasing © overall with propane initially decreased ID but eventually led to premature propane autoignition; however, the corresponding effects with methane were relatively minor. Cyclic variations in the start of combustion (SOC) increased with increasing © overall (at constant © pilot), more significantly for propane than for methane. With increasing PES at constant BMEP, the ID showed a nonlinear (initially increasing and later decreasing) trend at low BMEPs for propane but a linearly decreasing trend at high BMEPs. For methane, increasing PES only increased IDs at all BMEPs. At low BMEPs, increasing PES led to significantly higher cyclic SOC variations and SOC advancement for both propane and methane. Finally, the engine ignition delay (EID) was also shown to be a useful metric to understand the influence of ID on dual fuel combustion.

  5. Direct injection method for HPLC/MS/MS analysis of acrylamide in aqueous solutions: application to adsorption experiments. (United States)

    Mnif, Ines; Hurel, Charlotte; Marmier, Nicolas


    Polyacrylamides are polymers used in many fields and represent the main source of release of the highly toxic acrylamide in the environment. In this work, a simple, rapid, and sensitive analytical method was developed with HPLC/MS/MS and direct injection for acrylamide analysis in water and adsorption samples. AFNOR standards NF T90-210 and NF T90-220 were used for the analytical method validation and uncertainty estimation. Limit of quantification (LOQ) for acrylamide was 1 μg/L, and accuracy was checked at three acrylamide levels (1, 6, and 10 μg/L). Uncertainties were estimated at 34.2, 22, and 12.4 % for acrylamide concentrations at LOQ, 6 μg/L, and 10 μg/L, respectively. Acrylamide adsorption on clays (kaolinite, illite) and sludge was then studied as a function of pH, time, and acrylamide concentrations. Acrylamide adsorption on kaolinite, illite, and sludge was found to be very weak since adsorption percentages were inferior to 10 %, whatever the pH value and the initial acrylamide concentration. The low affinity of acrylamide for clays and sludge is likely due to its hydrophilic property, small size, and charge neutrality.

  6. Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth. (United States)

    Tsutsumi, Kae; Yamaura, Takeshi; Nakajima, Motowo; Honda, Toshiyuki; Kasaoka, Tatsuhiko


    Focal adhesion kinase (FAK) is shown to be frequently correlated with malignancy of the tumor and poor prognosis of the diseases.Because FAK resides immediately downstream of the interaction of cell surface adhesion molecules and extracellular matricies, it is considered to be critical to regulate several cellular processes including growth, differentiation, adhesion, motility and apoptosis. However, the studies on the role of FAK related to cell proliferation have been limited even in vitro. Here, in order to validate the role of FAK in in vivo tumor formation and proliferation, we employed direct intratumoral injection of short hairpin RNA (shRNA) targeting FAK with cationic liposome. Using shRNAs targeting FAK selected from the constructed shRNA library for FAK and by optimization of in vivo delivery conditions, we demonstrated different patterns of the association of FAK inhibition with in vivo tumor formation/proliferation inhibition in two models, PC3M heterotopic xenograft and 4T1 orthotopic syngraft models. These observations indicated that the roles of FAK in tumorigenesis are different among the tumor species. In addition, we showed that ERK is the critical MAP kinase in the signaling pathway down stream of FAK in in vivo proliferation of 4T1 tumor cells.

  7. High-speed fuel tracer fluorescence and OH radical chemiluminescence imaging in a spark-ignition direct-injection engine. (United States)

    Smith, James D; Sick, Volker


    An innovative technique has been demonstrated to achieve crank-angle-resolved planar laser-induced fluorescence (PLIF) of fuel followed by OH* chemiluminescence imaging in a firing direct-injected spark-ignition engine. This study used two standard KrF excimer lasers to excite toluene for tracking fuel distribution. The intensified camera system was operated at single crank-angle resolution at 2000 revolutions per minute (RPM) for 500 consecutive cycles. Through this work, it has been demonstrated that toluene and OH* can be imaged through the same optical setup while similar signal levels are obtained from both species, even at these high rates. The technique is useful for studying correlations between fuel distribution and subsequent ignition and flame propagation without the limitations of phase-averaging imaging approaches. This technique is illustrated for the effect of exhaust gas recirculation on combustion and will be useful for studies of misfire causes. Finally, a few general observations are presented as to the effect of preignition fuel distribution on subsequent combustion.

  8. Transient analysis of ”2 inch Direct Vessel Injection line break” in SPES-2 facility by using TRACE code (United States)

    D'Amico, S.; Lombardo, C.; Moscato, I.; Polidori, M.; Vella, G.


    In the past few decades a lot of theoretical and experimental researches have been done to understand the physical phenomena characterizing nuclear accidents. In particular, after the Three Miles Island accident, several reactors have been designed to handle successfully LOCA events. This paper presents a comparison between experimental and numerical results obtained for the “2 inch Direct Vessel Injection line break” in SPES-2. This facility is an integral test facility built in Piacenza at the SIET laboratories and simulating the primary circuit, the relevant parts of the secondary circuits and the passive safety systems typical of the AP600 nuclear power plant. The numerical analysis here presented was performed by using TRACE and CATHARE thermal-hydraulic codes with the purpose of evaluating their prediction capability. The main results show that the TRACE model well predicts the overall behaviour of the plant during the transient, in particular it is able to simulate the principal thermal-hydraulic phenomena related to all passive safety systems. The performance of the presented CATHARE noding has suggested some possible improvements of the model.

  9. Unambiguous identification and discovery of bacterial siderophores by direct injection 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Lawrence R.; Tfaily, Malak M.; Shaw, Jared B.; Hess, Nancy J.; Pasa Tolic, Ljiljana; Koppenaal, David W.


    Under iron-limiting conditions, bacteria produce low molecular mass Fe(III) binding molecules known as siderophores to sequester the Fe(III), along with other elements, increasing their bioavailibility. Siderophores are thought to influence iron cycling and biogeochemistry in both marine and terrestrial ecosystems and hence the need for rapid, confident characterization of these compounds has increased. In this study, the type of siderophores produced by two marine bacterial species, Synechococcus sp. PCC 7002 and Vibrio cyclitrophicus 1F53, were characterized using a newly developed 21T Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (FTICR MS) with direct injection electrospray ionization. This technique allowed for the rapid detection of synechobactins from Synechococcus sp. PCC 7002 as well as amphibactins from Vibrio cyclitrophicus 1F53 based on high mass accuracy and resolution allowing for observation of specific Fe isotopic peaks and fine isotopic structure enables highly confident identification of these sideropohores. When combined with molecular network analysis two new amphibactins were discovered and verified by tandem MS. These results show that high-field FTICR MS is a powerful technique that will greatly improve the ability to rapidly identify and discover metal binding species in the environment.

  10. On the effect of injection timing on the ignition of lean PRF/air/EGR mixtures under direct dual fuel stratification conditions

    KAUST Repository

    Luong, Minh Bau


    The ignition characteristics of lean primary reference fuel (PRF)/air/exhaust gas recirculation (EGR) mixture under reactivity-controlled compression ignition (RCCI) and direct duel fuel stratification (DDFS) conditions are investigated by 2-D direct numerical simulations (DNSs) with a 116-species reduced chemistry of the PRF oxidation. The 2-D DNSs of the DDFS combustion are performed by varying the injection timing of iso-octane (i-C8H18) with a pseudo-iso-octane (PC8H18) model together with a novel compression heating model to account for the compression heating and expansion cooling effects of the piston motion in an engine cylinder. The PC8H18 model is newly developed to mimic the timing, duration, and cooling effects of the direct injection of i-C8H18 onto a premixed background charge of PRF/air/EGR mixture with composition inhomogeneities. It is found that the RCCI combustion exhibits a very high peak heat release rate (HRR) with a short combustion duration due to the predominance of the spontaneous ignition mode of combustion. However, the DDFS combustion has much lower peak HRR and longer combustion duration regardless of the fuel injection timing compared to those of the RCCI combustion, which is primarily attributed to the sequential injection of i-C8H18. It is also found that the ignition delay of the DDFS combustion features a non-monotonic behavior with increasing fuel-injection timing due to the different effect of fuel evaporation on the low-, intermediate-, and high-temperature chemistry of the PRF oxidation. The budget and Damköhler number analyses verify that although a mixed combustion mode of deflagration and spontaneous ignition exists during the early phase of the DDFS combustion, the spontaneous ignition becomes predominant during the main combustion, and hence, the spread-out of heat release rate in the DDFS combustion is mainly governed by the direct injection process of i-C8H18. Finally, a misfire is observed for the DDFS combustion when

  11. Direct optical injection locking of monolithically integrated In(0.53)Ga(0.47)As/In(0.52)Al(0.48)As MODFET oscillators (United States)

    Yang, D.; Bhattacharya, P. K.; Brock, T.


    The authors have fabricated monolithically integrated In(0.53)Ga(0.47)As/In(0.52)Al(0.48)As 0.25-micron gate MODFET oscillators. The results of direct optical subharmonic injection locking of these oscillator circuits at 10.159 and 19.033 GHz are presented.

  12. Development and Validation of a Fast Procedure to Analyze Amoxicillin in River Waters by Direct-Injection LC-MS/MS (United States)

    Homem, Vera; Alves, Arminda; Santos, Lu´cia


    A laboratory application with a strong component in analytical chemistry was designed for undergraduate students, in order to introduce a current problem in the environmental science field, the water contamination by antibiotics. Therefore, a simple and rapid method based on direct injection and high performance liquid chromatography-tandem mass…

  13. Comparison of direct injection nebulizer and desolvating microconcentric nebulizer for analysis of chlorine-, bromine- and iodine-containing compounds by reversed phase HPLC with ICP-MS detection

    DEFF Research Database (Denmark)

    Jensen, B.P.; Gammelgaard, Bente; Hansen, S.H.


    With the purpose of finding ways to combine micro-bore reversed phase HPLC with ICP-MS detection for analysis of drug substances containing chlorine, bromine and iodine, the suitability of a direct injection nebulizer and an Aridus desolvating microconcentric nebulizer was compared. Using...

  14. Burning vasculitis. (United States)

    Chadha, Priyanka; Hobday, Dorian; O'Connor, Edmund Fitzgerald; D'Cruz, David


    We present the case of a 69-year-old man who was found collapsed close to a heat source and admitted to hospital for severe sepsis. He was also found to have widespread blistering and ulceration of his right leg; however, a history was unobtainable due to reduced consciousness levels. The leg lesions had the initial appearance of mixed depth burns and a management plan was made to transfer the patient to a burns unit for debridement. It was subsequently noted that the patient had a previous diagnosis of seropositive erosive rheumatoid arthritis. A biopsy of the leg lesion was performed and a diagnosis of rheumatoid vasculitis confirmed. Treatment with systemic steroids, intravenous antibiotics and intravenous immunoglobulin therapy for severe hypogammaglobulinaemia was started, and the patient was not transferred for surgical debridement. Rheumatoid vasculitis is a rare and extremely serious complication of rheumatoid arthritis that can manifest in a number of ways, occasionally mimicking other conditions. This case is essential to raise awareness of rare, severe rheumatoid vasculitis and of the potential for its misdiagnosis as a mixed depth burn.

  15. In vitro fertilization and intracytoplasmic sperm injection for couples with unexplained infertility after failed direct intraperitoneal insemination. (United States)

    Takeuchi, S; Minoura, H; Shibahara, T; Shen, X; Futamura, N; Toyoda, N


    The objective was to determine the optimal insemination technique in patients undergoing in vitro fertilization (IVF) after failed direct intraperitoneal insemination (DIPI) and the outcome of intracytoplasmic sperm injection (ICSI) in such cases. In case-control studies, 53 couples with unexplained infertility who underwent IVF after four failed DIPI cycles were compared with 75 couples with tubal or endometriosis infertility as controls. Thirty couples with unexplained infertility after failing to conceive with DIPI and conventional IVF who underwent ICSI and 58 couples with male-factor infertility as controls also were compared. Fertilization cleavage, embryo quality, implantation, and pregnancy were compared after IVF and after ICSI. There was a significant difference in fertilization rates after IVF between cases of unexplained infertility after failing to conceive with DIPI (40.4%) and patients with tubal or endometriosis infertility (67.9%). There also was a significant difference in total fertilization failure rates between the two groups (30.4% and 3.9%, respectively). There was a slight but significant difference in numbers of fertilized oocytes after ICSI between patients with low fertilization rate undergoing IVF after failing to conceive DIPI (85.8%) and patients with male factor (90.4%). Total fertilization failure was not observed in these cases. Couples with unexplained infertility after failing to conceive with DIPI show a failed fertilization or a low fertilization rate after IVF. However, they demonstrated a good chance of becoming pregnant after subsequent ICSI, even with statistically significant difference in fertilization rate as compared with male-factor cases.

  16. Murine precision-cut lung slices exhibit acute responses following exposure to gasoline direct injection engine emissions. (United States)

    Maikawa, Caitlin L; Zimmerman, Naomi; Rais, Khaled; Shah, Mittal; Hawley, Brie; Pant, Pallavi; Jeong, Cheol-Heon; Delgado-Saborit, Juana Maria; Volckens, John; Evans, Greg; Wallace, James S; Godri Pollitt, Krystal J


    Gasoline direct injection (GDI) engines are increasingly prevalent in the global vehicle fleet. Particulate matter emissions from GDI engines are elevated compared to conventional gasoline engines. The pulmonary effects of these higher particulate emissions are unclear. This study investigated the pulmonary responses induced by GDI engine exhaust using an ex vivo model. The physiochemical properties of GDI engine exhaust were assessed. Precision cut lung slices were prepared using Balb/c mice to evaluate the pulmonary response induced by one-hour exposure to engine-out exhaust from a laboratory GDI engine operated at conditions equivalent to vehicle highway cruise conditions. Lung slices were exposed at an air-liquid interface using an electrostatic aerosol in vitro exposure system. Particulate and gaseous exhaust was fractionated to contrast mRNA production related to polycyclic aromatic hydrocarbon (PAH) metabolism and oxidative stress. Exposure to GDI engine exhaust upregulated genes involved in PAH metabolism, including Cyp1a1 (2.71, SE=0.22), and Cyp1b1 (3.24, SE=0.12) compared to HEPA filtered air (pengine exhaust further increased Cyp1b1 expression compared to filtered GDI engine exhaust (i.e., gas fraction only), suggesting this response was associated with the particulate fraction. Exhaust particulate was dominated by high molecular weight PAHs. Hmox1, an oxidative stress marker, exhibited increased expression after exposure to GDI (1.63, SE=0.03) and filtered GDI (1.55, SE=0.04) engine exhaust compared to HEPA filtered air (pengine exhaust contributes to upregulation of genes related to the metabolism of PAHs and oxidative stress.

  17. An update on blast furnace granular coal injection

    Energy Technology Data Exchange (ETDEWEB)

    Hill, D.G. [Bethlehem Steel Corp., Burns Harbor, IN (United States); Strayer, T.J.; Bouman, R.W. [Bethlehem Steel Corp., PA (United States)


    A blast furnace coal injection system has been constructed and is being used on the furnace at the Burns Harbor Division of Bethlehem Steel. The injection system was designed to deliver both granular (coarse) and pulverized (fine) coal. Construction was completed on schedule in early 1995. Coal injection rates on the two Burns Harbor furnaces were increased throughout 1995 and was over 200 lbs/ton on C furnace in September. The injection rate on C furnace reached 270 lbs/ton by mid-1996. A comparison of high volatile and low volatile coals as injectants shows that low volatile coal replaces more coke and results in a better blast furnace operation. The replacement ratio with low volatile coal is 0.96 lbs coke per pound of coal. A major conclusion of the work to date is that granular coal injection performs very well in large blast furnaces. Future testing will include a processed sub-bituminous coal, a high ash coal and a direct comparison of granular versus pulverized coal injection.

  18. Successful management with glue injection of arterial rupture seen during embolization of an arteriovenous malformation using a flow-directed catheter: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jong Won; Baik, Seung Kug; Shin, Mi Jung; Choi, Han Yong; Kim, Bong Gi [Wallace Memorial Baptist Hospital, Pusan (Korea, Republic of)


    We present a case in which an arterial rupture occurring during embolization of an arteriovenous malformation of the left occipital lobe with a flow-directed micro-catheter, was successfully sealed with a small amount of glue. We navigated a 1.8-Fr Magic catheter through the posterior cerebral artery, and during superselective test injection, extravasation was observed at the parieto-occipital branch. The catheter was not removed and the perforation site was successfully sealed with a small amount of glue injected through the same catheter. Prompt recognition and closure of the perforation site is essential for good prognosis. (author)

  19. Direct cardiac injection of G-CSF mobilized bone-marrow stem-cells improves ventricular function in old myocardial infarction. (United States)

    Archundia, Abel; Aceves, José Luis; López-Hernández, Manuel; Alvarado, Martha; Rodriguez, Emma; Díaz Quiroz, Guillermo; Páez, Araceli; Rojas, Felipe Masso; Montaño, Luis Felipe


    Autologous transplant of bone marrow stem cells (BMSC), although extremely useful after acute myocardial events, has not been evaluated in patients with old (>one-year-old) myocardial infarction. Our aim was to determine if CD34(+)-enriched peripheral-blood cells, obtained by apheresis, injected directly into the severely damaged myocardium of five patients with old myocardial infarction could restore depressed myocardial function. We found that 28 weeks after revascularization and peri-infarction injection of the enriched CD34(+) peripheral mononuclear cells, ventricular hemodynamic parameters that included left ventricular ejection fraction, left ventricular diastolic volume, ventricular systolic volume and left ventricular diastolic diameter approximated normal values and there was no restenosis; two patients have been followed for >52 weeks and their parameters are within normal values. In conclusion, intramyocardial injection of easily obtained CD34(+) enriched peripheral blood cells represent an encouraging procedure for patients with severely scarred and dysfunctional myocardium.

  20. First Aid: Burns (United States)

    ... Your 1- to 2-Year-Old First Aid: Burns KidsHealth > For Parents > First Aid: Burns A A A Scald burns from hot water and other liquids are the most common burns in early childhood. Because burns range from mild ...

  1. First Aid: Burns (United States)

    ... Old Feeding Your 8- to 12-Month-Old Feeding Your 1- to 2-Year-Old First Aid: Burns KidsHealth > For Parents > First Aid: Burns Print A A A Scald burns from hot water and other liquids are the most common burns in early childhood. Because burns range from mild to life threatening, ...

  2. Computational Simulation of Fuel Nozzle Multi Holes Geometries Effect on Direct Injection Diesel Engine Performance Using GT-POWER

    Directory of Open Access Journals (Sweden)

    Rosli A. Bakar


    Full Text Available The computational model simulation development is use the commercial computational fluid dynamics of GT-POWER 6.2 software were specially development for internal combustion engines performance simulation. The research concentrated on one dimensional model and focuses on fuel nozzles multi holes geometries variation developed from all of the engine components size measurement of the original selected diesel engine. All of the measurements data input to the window engines component menu for running input data in the model. Results of the diesel engine fuel nozzles multi holes geometries model simulation running is in GT-POST. The model performance shows in engine cylinder and engine crank-train on software window output. The performance analysis effect of the model investigated of fuel in-cylinder engine, indicated specific fuel consumption, indicated torque and indicated power of engine modeled. The simulation result was shows that the seven holes nozzle provided the best burning for fuel in-cylinder burned and the five holes nozzle provided the best for indicted power, indicated torque and indicated specific fuel consumption in any different engine speed in simulation.

  3. Burns (For Parents) (United States)

    ... Child What Kids Say About: Handling Stress Anxiety, Fears, and Phobias Community Service: A Family's Guide to Getting ... What's in this article? Common Causes Types of Burns First-Degree Burns Second-Degree Burns ...

  4. Sarilumab Injection (United States)

    ... the needle. Do not try to warm the medication by heating it in a microwave, placing it in warm water or in direct sunlight, or through any other method.Before injecting, check the prefilled syringe to be sure that the expiration date printed on the package has not passed. Look ...

  5. Developments in Spray Modeling in Diesel and Direct-Injection Gasoline Engines Progrès de la modélisation des sprays dans les moteurs Diesel et à essence


    Kong S. C.; Senecal P. K.; Reitz R. D.


    In direct-injection engines, the fuel spray characteristics influence the combustion efficiency and exhaust emissions. The performance of available spray models for predicting liquid and vapor fuel distributions, and their influence on combustion is reviewed for both diesel and gasoline direct injection engines. A phenomenological nozzle flow model is described for simulating the effects of diesel injector nozzle internal geometry on the fuel injection and spray processes. The flow model prov...

  6. Effects of fuel and air mixing on WOT output in direct injection gasoline engine; Chokufun gasoline kikan ni okeru nenryo to kuki no kongo to shutsuryoku seino

    Energy Technology Data Exchange (ETDEWEB)

    Noda, T.; Iriya, Y.; Naito, K.; Mitsumoto, H.; Iiyama, A. [Nissan Motor Co. Ltd., Tokyo (Japan)


    The effects of in-cylinder charge motion and the characteristics of the fuel spray and piston crown shape on WOT output in a direct injection gasoline engine are investigated. The fuel and air mixing process in a cylinder is analyzed by computer simulation and LIF method visualization. As a result, the technical factors to achieve enough mixing in a DI gasoline engine equipped with bowl in piston optimized for stratified combustion are clarified. 7 refs., 9 figs., 1 tab.

  7. Epoetin Alfa Injection (United States)

    ... Combivir), a medication used to treat human immunodeficiency virus (HIV). Epoetin alfa injection is also used before ... inject epoetin alfa, as directed by your doctor. Write down the date, time, dose of epoetin alfa ...

  8. Natural gas in a D. I. diesel engine. A comparison of two different ways. [Direct injection diesel enginer

    Energy Technology Data Exchange (ETDEWEB)

    Jun-ming, Qu; Sorenson, S.C.; Kofoed, E.


    A D.I. diesel engine was modified for natural gas operation with pilot injection and with spark ignition so that a comparative analysis of these two different ways of using natural gas could be made. The results of the experiments indicate that for a diesel engine, it is possible that the operating characteristics of a straight natural gas engine are comparable with those of a diesel/gas engine at the same compression ratio and speed. For a dual fuel engine with pilot injection the best diesel/gas ratio by energy content is approximately 20/80 at full load operation. For straight natural gas engine with spark ignition, quality governed natural gas operation has good efficiency but poor NOx emissions. This problem could be improved through throttle controlled operation. These two different ways of using natural gas are best suited to stationary engines.

  9. Direct Injection of Seawater for the Analysis of Nitroaromatic Explosives and their Degradation Products by Micellar Electrokinetic Chromatography (United States)


    micellar electrokinetic chromatography Braden C. Giordanoa,∗, Dean S. Burgib, Greg E. Collinsa a Uanited States Naval Research Laboratory, Chemistry...threats to our coastal regions. Micellar electrokinetic chromatography (MEKC) has been demonstrated to be a useful analytical tool in the anal- ysis of...injection of seawater for the analysis of nitroaromatic explosives and their degradation products by micellar electrokinetic chromatography 5a. CONTRACT

  10. Simulation of Kinematics Characteristics of a Direct Injection Gasoline Engine at Direct Start%直接起动阶段直喷汽油机运动特性的模拟

    Institute of Scientific and Technical Information of China (English)

    曹志成; 何邦全


    建立了直喷汽油机的三维数值模型和运动学模型,并进行了试验验证。模拟了直喷汽油机在直接起动过程中不同喷油策略和点火时刻下的燃烧特性、反转和正转过程的运动特性。结果表明:与单次喷油相比,采用两次喷油策略时,首个着火气缸内混合气燃烧后的最大气缸压力较大,而且其大小受到点火时刻的影响;首个着火气缸内混合气燃烧后的最大气缸压力较大,则直喷汽油机反转过程中转过的最大角度较大;在各种喷油条件下,第2个着火气缸在反转到其最大转角前2°左右点火,正转过程转速较高,有利于直喷汽油机的直接起动。%A three-dimensional model and a one-dimensional kinematics model for a direct injec-tion gasoline engine were established and validated through engine experiments.The combustion characteristics in the first firing cylinder and the kinematics characteristics of the engine under the conditions of forward and reverse rotation were simulated when different fuel injection methods and spark ignition timings were employed at direct start.The results show that the peak cylinder pressure in the first firing cylinder after combustion in the cases of split injection is higher than that at single injection.But its magnitude is affected by spark ignition timing.Higher peak cylinder pressure increa-ses the crank angles,which the engine can move in the reverse rotation direction.The engine speed in the forward rotation direction is the largest when the sequent cylinder is ignited at about 2°before the biggest reverse crank angles in both single injection and split injection,which is helpful to a successful direct start.

  11. 玉米秸秆生物油-柴油乳化油的燃烧特性%Combustion Characteristics of a Direct Injection Diesel Engine Operating on Emulsions from Corn Stalk Bio-Oil and Diesel Fuel

    Institute of Scientific and Technical Information of China (English)

    黄勇成; 韩旭东; 尚上; 王丽


    The experimental bio-oil produced from corn stalk through fast pyrolysis process is mainly composed of oxygenated organic and water, thereby restricting its direct use as fuel. However, the use of bio-oil in diesel engines can be realized by developing emulsions from bio-oil and diesel fuel. In this paper, two emulsions with 10% and 20% by mass fraction of bio-oil in diesel fuel, represented by B10 and B20 respectively, were prepared by using ultrasonic emulsification method. Then, the combustion characteristics of an unmodified direct injection diesel engine operating on the two emulsions were studied. The results show that the engine operating on the two emulsions displays a longer ignition delay, exhibits a higher peak value of premixed burning rate and pressure rise rate and a slightly lower peak value of diffusion burning rate, displays a lower peak combustion pressure and average combustion temperature, and has a shorter combustion duration when compared with No.0 diesel. In comparison with B10, B20 has a longer ignition delay, while exhibits a lower peak value of premixed burning rate, pressure rise rate, in-cylinder pressure and combustion temperature. In addition, the fuel economy for B10 operation is comparable to that for No.0 diesel operation, while the fuel economy of B20 is poorer than that of No.0 diesel.%试验用生物油是玉米秸秆快速热解液化的产物,主要成分为含氧有机混合物和水,不宜直接作为燃料使用,但与柴油乳化后可实现其在发动机中应用.在一台未作改动的直喷式柴油机上研究了玉米秸秆生物油质量分数分别为10%(B10)和20%(B20)的生物油-柴油乳化油的燃烧特性.结果表明:与0号柴油相比,乳化油的滞燃期延长,预混燃烧放热峰值和最大压力升高率升高,扩散燃烧放热峰值略低,最高燃烧压力和缸内气体平均温度降低,燃烧持续期缩短.与B10相比,B20的滞燃期延长,而预混燃烧放热峰值、最大压力升

  12. Gadolinium contrast media are more nephrotoxic than iodine media. The importance of osmolality in direct renal artery injections

    Energy Technology Data Exchange (ETDEWEB)

    Elmstaahl, Barbara; Leander, Peter; Almen, Torsten [Malmoe University Hospital, Lund University, Department of Diagnostic Radiology, Malmoe (Sweden); Nyman, Ulf [Lasarettet Trelleborg, Department of Radiology, Trelleborg (Sweden); Chai, Chun-Ming [Malmoe University Hospital, Lund University, Department of Experimental Research, Malmoe (Sweden); Golman, Klaes [Biosciences, GE Health, Malmoe (Sweden); Bjoerk, Jonas [University Hospital, Lund University, Competence Center for Clinical Research, Lund (Sweden)


    A study was undertaken of the role of osmotoxicity in gadolinium (Gd) and iodine contrast media (CM) nephrotoxicity in ischemic porcine kidneys. Test solutions: mannitol iso-osmotic to 0.5 M gadopentetate (1.96 Osm/kg H{sub 2}O), 0.5 M gadodiamide (0.78 Osm/kg H{sub 2}O) and 0.5 M iohexol (190 mg I/ml, 0.42 Osm/kg H{sub 2}O). Each solution was injected [3 ml/kg body weight (BW)] into the balloon-occluded (10 min) renal artery of eight left-sided nephrectomized pigs. The plasma half-life of a glomerular filtration rate (GFR) marker was used to compare their effects on GFR 1-3 h post-injection. The median half-lives of the GFR marker after injection of gadopentetate (1,730 min) and mannitol 1.96 Osm/kg H{sub 2}O (2,782 min) did not differ statistically (P=0.28), but were significantly longer than after all other solutions (P<0.001). There was no significant difference (P=0.06) between gadodiamide (218 min) and mannitol 0.82 Osm/kg H{sub 2}O (169 min), while there was (P=0.03) between iohexol (181 min) and mannitol 0.43 Osm/kg H{sub 2}O (148 min). The difference between gadodiamide and iohexol was significant (P=0.01). Reduction in GFR, as a marker of nephrotoxicity, induced by gadopentetate correlated with its high osmolality, while the effect of gadodiamide and iohexol may include chemotoxicity. Iohexol molecules were less nephrotoxic than the Gd-CM molecules and contain three-times the number of attenuating atoms per molecule. (orig.)

  13. Optical 16-QAM-52-OFDM transmission at 4 Gbit/s by directly modulating a coherently injection-locked colorless laser diode. (United States)

    Chi, Yu-Chieh; Li, Yi-Cheng; Wang, Huai-Yung; Peng, Peng-Chun; Lu, Hai-Han; Lin, Gong-Ru


    Coherently injection-locked and directly modulated weak-resonant-cavity laser diode (WRC-FPLD) for back-to-back optical 16-quadrature-amplitude-modulation (QAM) and 52-subcarrier orthogonal frequency division multiplexing (OFDM) transmission with maximum bit rate up to 4 Gbit/s at carrier frequency of 2.5 GHz is demonstrated. The WRC-FPLD transmitter source is a specific design with very weak-resonant longitudinal modes to preserve its broadband gain spectral characteristics for serving as a colorless WDM-PON transmitter. Under coherent injection-locking, the relative-intensity noise (RIN) of the injection-locked WRC-FPLD can be suppressed to ?105 dBc/Hz and the error vector magnitude of the received optical OFDM data is greatly reduced with the amplitude error suppressed down 5.5%. Such a coherently injection-locked single-mode WRC-FPLD can perform both the back-to-back and the 25-km-SMF 16-QAM-52-OFDM transmissions with a symbol rate of 20-MSa/s in each OFDM subcarrier. After coherent injection locking, the BER of the back-to-back transmitted 16-QAM-52-OFDM data is reduced to 2.5 × 10(-5) at receiving power of ?10 dBm. After propagating along a 25-km-long SMF, a receiving power sensitivity of ?7.5 dBm is required to obtain a lowest BER of 2.5 × 10(-5), and a power penalty of 2.7 dB is observed when comparing with the back-to-back transmission.

  14. Theoretical aspects for estimating anisotropic saturated hydraulic conductivity from in-well or direct-push probe injection tests in uniform media (United States)

    Klammler, Harald; Layton, Leif; Nemer, Bassel; Hatfield, Kirk; Mohseni, Ana


    Hydraulic conductivity and its anisotropy are fundamental aquifer properties for groundwater flow and transport modeling. Current in-well or direct-push field measurement techniques allow for relatively quick determination of general conductivity profiles with depth. However, capabilities for identifying local scale conductivities in the horizontal and vertical directions are very limited. Here, we develop the theoretical basis for estimating horizontal and vertical conductivities from different types of steady-state single-well/probe injection tests under saturated conditions and in the absence of a well skin. We explore existing solutions and a recent semi-analytical solution approach to the flow problem under the assumption that the aquifer is locally homogeneous. The methods are based on the collection of an additional piece of information in the form of a second injection (or recirculation) test at a same location, or in the form of an additional head or flow observation along the well/probe. Results are represented in dimensionless charts for partial validation against approximate solutions and for practical application to test interpretation. The charts further allow for optimization of a test configuration to maximize sensitivity to anisotropy ratio. The two methods most sensitive to anisotropy are found to be (1) subsequent injection from a lateral screen and from the bottom of an otherwise cased borehole, and (2) single injection from a lateral screen with an additional head observation along the casing. Results may also be relevant for attributing consistent divergences in conductivity measurements from different testing methods applied at a same site or location to the potential effects of anisotropy. Some practical aspects are discussed and references are made to existing methods, which appear easily compatible with the proposed procedures.

  15. Integration of the Smart NOx-Sensor in the exhaust line of a gasoline high pressure direct injection system; Integration eines Smart NOx-Sensors im Abgasstrang fuer die Benzindirekteinspritzung

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Hong; Pfleger, C.; Lemire, B. [Siemens AG Automobiltechnik, Regensburg (Germany)


    For further reduction of fuel consumption of Gasoline engines the High Pressure Direct Injection is the most suitable way. For the exhaust gas aftertreatment NOx storage catalysts are used, which stores the NOx emission in lean burn phases and reduce it in short phases with rich mixture. To trigger the start of the regeneration phases suitable models can be used. The optimum start of the regeneration phase concerning emission and consumption is only possible with the use of a NOx-Sensor, so that further stringent emission regulation and OBD II requirements will force the use of the NOx-Sensor. Siemens Automotive in cooperation with NGK Insulators are developping in cooperation the 'Smart' NOx-Sensor, which can be integrated in the ECU. With this configuration all requirements concerning emission, fuel consumption and diagnosis can be fulfilled. (orig.) [German] Die Benzindirekteinspritzung bietet ein hohes Potential fuer die Reduzierung des Kraftstoffverbrauchs. Fuer die Abgasnachbehandlung werden NOx-Speicherkatalysatoren eingesetzt, die in den mageren Motorbetriebsphasen die entstehenden Stickoxide speichern und in kurzen Motorbetriebsphasen mit fettem Gemisch diese regenerieren. Fuer die Einleitung der Regenerationsphasen bieten sich geeignete Modelle an. Die sowohl emissions- wie auch verbrauchsoptimale Einleitung der Regenerationsphase ist jedoch nur mit dem Einsatz eines NOx-Sensors moeglich, wobei die zunehmend strenger werdenden Emissions- und Diagnosevorschriften der emissionsbeeinflussenden Bauteile den Einsatz des NOx-Sensors erfordern werden. Siemens Automobiltechnik entwickelt in Zusammenarbeit mit NGK Insulator einen NOx-Sensor, der in die Motorsteuerung eingebunden werden kann. Mit dieser Konfiguration lassen sich alle Anforderungen an das Motorsteuergeraet und die Abgasnachbehandlung bezueglich Kraftstoffverbrauch, Emissionen und Diagnose erfuellen. (orig.)

  16. Direct intracranial injection of AAVrh8 encoding monkey β-N-acetylhexosaminidase causes neurotoxicity in primate brain. (United States)

    Golebiowski, Diane; van der Bom, Imramsjah Martijn J; Kwon, Churl-Su; Miller, Andrew D; Petrosky, Keiko; Bradbury, Allison M; Maitland, Stacy; Kühn, Anna Luisa; Bishop, Nina; Curran, Elizabeth; Silva, Nilsa; GuhaSarkar, Dwijit; Westmoreland, Susan V; Martin, Douglas R; Gounis, Matthew J; Asaad, Wael F; Sena-Esteves, Miguel


    GM2 gangliosidoses, including Tay-Sachs disease (TSD) and Sandhoff disease (SD), are lysosomal storage disorders caused by deficiencies in β-N-acetylhexosaminidase (Hex). Patients are afflicted primarily with progressive central nervous system dysfunction (CNS). Studies in mice, cats, and sheep have indicated safety and widespread distribution of Hex in the CNS after intracranial vector infusion of AAVrh8 vectors encoding species-specific Hex α- or β-subunits at a 1:1 ratio. Here we conducted a safety study in cynomolgus macaques (cm) modeling our previous animal studies with bilateral infusion in the thalamus as well as in left lateral ventricle of AAVrh8 vectors encoding cm Hex α- and β-subunits. Three doses (3.2 x 1012 vg (n=3), 3.2 x 1011 vg (n=2), or 1.1 x 1011 vg (n=2)) were tested with controls infused with vehicle (n=1), or transgene empty AAVrh8 vector at the highest dose (n=2). Most monkeys receiving AAVrh8-cmHexα/β developed dyskinesias, ataxia, and loss of dexterity, with higher dose animals eventually becoming apathetic. Time to onset of symptoms was dose-dependent with the highest dose cohort producing symptoms within a month of infusion. One monkey in the lowest dose cohort was behaviorally asymptomatic but had MRI abnormalities in thalami. Histopathology was similar in all monkeys injected with AAVrh8-cmHexα/β showing severe white and gray matter necrosis along the injection track, reactive vasculature, and the presence of neurons with granular eosinophilic material. Lesions were minimal to absent in both control cohorts. Despite cellular loss, a dramatic increase in Hex activity was measured in the thalamus and none of the animals presented with antibody titers against Hex. The high overexpression of Hex protein is likely to blame for this negative outcome and this study demonstrates the variations in safety profiles of AAVrh8-Hex α/β intracranial injection among different species despite encoding for self-proteins.

  17. Burn Injuries: Burn Depth, Physiopathology and Type of Burns

    Directory of Open Access Journals (Sweden)

    Kemalettin Koltka


    Full Text Available A significant burn injury is a serious and mortal event. The most important threat to life is hypovolemic shock with complex pathophysiologic mechanisms. Burn depth is classified as first, second, or third degree. Local inflammatory response results a vasodilatation and an increase in vascular permeability. A burn injury is a three dimensional ischemic wound. Zone of coagulation is the zone with maximum damage. Zone of stasis consists of damaged but viable tissues, the tissue is salvageable. In zone of hyperemia tissue perfusion is increased. At the beginning, cardiac output falls and systemic vascular resistance increases; cardiac performance improves as hypovolemia is corrected with fluid resuscitation. While cardiac output increases systemic vascular resistance falls below normal values and a hypermetabolic state develops. Pulmonary vascular resistance increases immediately after thermal injury and this is more prolonged. To avoid secondary pulmonary complications, the smallest resuscitation volume of fluids that maintains adequate tissue perfusion should be given. Changes parallel to the cardiovascular response develop in other organ systems. The reasons of burn injury can be thermal, electrical, chemical or radiation. It is important to know the exact mechanism of burn injury because of different therapies for a specific cause. In this review information about burn depth, local and systemic responses to burn injury and major causes of burn injury are presented. (Journal of the Turkish Society Intensive Care 2011; 9 Suppl:1-6

  18. Accurate determination of sulfur in gasoline and related fuel samples using isotope dilution ICP-MS with direct sample injection and microwave-assisted digestion. (United States)

    Heilmann, Jens; Boulyga, Sergei F; Heumann, Klaus G


    Inductively coupled plasma isotope-dilution mass spectrometry (ICP-IDMS) with direct injection of isotope-diluted samples into the plasma, using a direct injection high-efficiency nebulizer (DIHEN), was applied for accurate sulfur determinations in sulfur-free premium gasoline, gas oil, diesel fuel, and heating oil. For direct injection a micro-emulsion consisting of the corresponding organic sample and an aqueous 34S-enriched spike solution with additions of tetrahydronaphthalene and Triton X-100, was prepared. The ICP-MS parameters were optimized with respect to high sulfur ion intensities, low mass-bias values, and high precision of 32S/34S ratio measurements. For validation of the DIHEN-ICP-IDMS method two certified gas oil reference materials (BCR 107 and BCR 672) were analyzed. For comparison a wet-chemical ICP-IDMS method was applied with microwave-assisted digestion using decomposition of samples in a closed quartz vessel inserted into a normal microwave system. The results from both ICP-IDMS methods agree well with the certified values of the reference materials and also with each other for analyses of other samples. However, the standard deviation of DIHEN-ICP-IDMS was about a factor of two higher (5-6% RSD at concentration levels above 100 mircog g(-1)) compared with those of wet-chemical ICP-IDMS, mainly due to inhomogeneities of the micro-emulsion, which causes additional plasma instabilities. Detection limits of 4 and 18 microg g(-1) were obtained for ICP-IDMS in connection with microwave-assisted digestion and DIHEN-ICP-IDMS, respectively, with a sulfur background of the used Milli-Q water as the main limiting factor for both methods.

  19. Cycle-by-cycle Variations in a Direct Injection Hydrogen Enriched Compressed Natural Gas Engine Employing EGR at Relative Air-Fuel Ratios.

    Directory of Open Access Journals (Sweden)

    Olalekan Wasiu Saheed


    Full Text Available Since the pressure development in a combustion chamber is uniquely related to the combustion process, substantial variations in the combustion process on a cycle-by-cycle basis are occurring. To this end, an experimental study of cycle-by-cycle variation in a direct injection spark ignition engine fueled with natural gas-hydrogen blends combined with exhaust gas recirculation at relative air-fuel ratios was conducted. The impacts of relative air-fuel ratios (i.e. λ = 1.0, 1.2, 1.3 and 1.4 which represent stoichiometric, moderately lean, lean and very lean mixtures respectively, hydrogen fractions and EGR rates were studied. The results showed that increasing the relative air-fuel ratio increases the COVIMEP. The behavior is more pronounced at the larger relative air-fuel ratios. More so, for a specified EGR rate; increasing the hydrogen fractions decreases the maximum COVIMEP value just as increasing in EGR rates increases the maximum COVIMEP value. (i.e. When percentage EGR rates is increased from 0% to 17% and 20% respectively. The maximum COVIMEP value increases from 6.25% to 6.56% and 8.30% respectively. Since the introduction of hydrogen gas reduces the cycle-by-cycle combustion variation in engine cylinder; thus it can be concluded that addition of hydrogen into direct injection compressed natural gas engine employing EGR at various relative air-fuel ratios is a viable approach to obtain an improved combustion quality which correspond to lower coefficient of variation in imep, (COVIMEP in a direct injection compressed natural gas engine employing EGR at relative air-fuel ratios.

  20. Accurate determination of sulfur in gasoline and related fuel samples using isotope dilution ICP-MS with direct sample injection and microwave-assisted digestion

    Energy Technology Data Exchange (ETDEWEB)

    Heilmann, Jens; Boulyga, Sergei F.; Heumann, Klaus G. [Johannes Gutenberg-University, Institute of Inorganic Chemistry and Analytical Chemistry, Mainz (Germany)


    Inductively coupled plasma isotope-dilution mass spectrometry (ICP-IDMS) with direct injection of isotope-diluted samples into the plasma, using a direct injection high-efficiency nebulizer (DIHEN), was applied for accurate sulfur determinations in sulfur-free premium gasoline, gas oil, diesel fuel, and heating oil. For direct injection a micro-emulsion consisting of the corresponding organic sample and an aqueous {sup 34}S-enriched spike solution with additions of tetrahydronaphthalene and Triton X-100, was prepared. The ICP-MS parameters were optimized with respect to high sulfur ion intensities, low mass-bias values, and high precision of {sup 32}S/{sup 34}S ratio measurements. For validation of the DIHEN-ICP-IDMS method two certified gas oil reference materials (BCR 107 and BCR 672) were analyzed. For comparison a wet-chemical ICP-IDMS method was applied with microwave-assisted digestion using decomposition of samples in a closed quartz vessel inserted into a normal microwave system. The results from both ICP-IDMS methods agree well with the certified values of the reference materials and also with each other for analyses of other samples. However, the standard deviation of DIHEN-ICP-IDMS was about a factor of two higher (5-6% RSD at concentration levels above 100 {mu}g g{sup -1}) compared with those of wet-chemical ICP-IDMS, mainly due to inhomogeneities of the micro-emulsion, which causes additional plasma instabilities. Detection limits of 4 and 18 {mu}g g{sup -1} were obtained for ICP-IDMS in connection with microwave-assisted digestion and DIHEN-ICP-IDMS, respectively, with a sulfur background of the used Milli-Q water as the main limiting factor for both methods. (orig.)

  1. Modeling of Nitric Oxide Formation in Single Cylinder Direct Injection Diesel Engine Using Diesel-Water Emulsion

    Directory of Open Access Journals (Sweden)

    K. Kannan


    Full Text Available Problem statement: Water injection into the combustion chamber of diesel engine found to be one of best method for in-cylinder control of NOx formation. Approach: The combustion of water-diesel emulsion in diesel engine was simulated using a computer program to estimate the heat release rate, cylinder pressure, brake thermal efficiency, brake specific fuel consumption and NO formation. Results: The numerical simulation was performed at different equivalence ratios, engine speeds and water percentages. The numerical simulation was preferred to study the combustion behavior and emission of diesel engine because the experimental investigations were time consuming and costly affair. Conclusion/Recommendations: Experiments also conducted to validate the predicted results of computer simulation. Though the zero dimensional simulation models predicted NO formation during combustion process, the first appearance of NO could not be identified using this method which can be solved by CFD technique.

  2. Technique for iliopsoas ultrasound-guided active electromyography-directed botulinum a toxin injection in cerebral palsy. (United States)

    Willenborg, Michael J; Shilt, Jeffrey S; Smith, Beth Paterson; Estrada, Roquel L; Castle, Jason A; Koman, L Andrew


    Symptomatic hip flexion deformity secondary to iliopsoas spasticity may interfere with gait, impair sitting balance, or contribute to hip subluxation or dislocation. A nonsurgical, minimally invasive technique to ameliorate iliopsoas spasticity is presented. The technique uses intramuscular injections of botulinum A toxin to provide selective neuromuscular blockade of the iliacus or psoas muscles or both. Because of the anatomic location of the target muscles, this technique uses ultrasound guidance for needle placement. Active electromyographic stimulation is used to verify the needle position adjacent to active myoneural interfaces. The authors' experience to date includes the treatment of 28 patients (53 hips). Use of this technique has resulted in improved hip range of motion. No intraoperative or postoperative adverse events or complications have been observed.

  3. Emergency in Burn; Burn in Emergency

    Directory of Open Access Journals (Sweden)

    Yalcin Bayram


    Full Text Available Physicians who first meet with burned patients are often emergency service employees. When the patient was admitted to emergency service, especially in patients with major burn injury, is a matter should be dealt with strongly. Before sending the patients to a burn center, some interventions could became life saving which should be done as a first line treatment. Herein, review of the literature related to emergency burn treatment was performed and presented to all physicians as a summary guide. In addition, some questions such as how should be physician, who first meet with the burned patient, evaluated the patient, what should be physician paid attention, which principles should be employed for fluid replacement, how should be approached to burn wound are tried to be addressed. [TAF Prev Med Bull 2012; 11(3.000: 365-368

  4. Time-domain measurement of terahertz frequency magnetoplasmon resonances in a two-dimensional electron system by the direct injection of picosecond pulsed currents

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jingbo; Mayorov, Alexander S.; Wood, Christopher D.; Mistry, Divyang; Li, Lianhe; Linfield, Edmund H.; Giles Davies, A.; Cunningham, John E., E-mail: [School of Electronic and Electrical Engineering, University of Leeds, Woodhouse Lane, Leeds LS2 9JT (United Kingdom); Sydoruk, Oleksiy [Optical and Semiconductor Devices Group, Department of Electrical and Electronic Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ (United Kingdom)


    We have investigated terahertz (THz) frequency magnetoplasmon resonances in a two-dimensional electron system through the direct injection of picosecond duration current pulses. The evolution of the time-domain signals was measured as a function of magnetic field, and the results were found to be in agreement with calculations using a mode-matching approach for four modes observed in the frequency range above 0.1 THz. This introduces a generic technique suitable for sampling ultrafast carrier dynamics in low-dimensional semiconductor nanostructures at THz frequencies.

  5. Ultrasound-assisted emulsification microextraction for the determination of ephedrines in human urine by capillary electrophoresis with direct injection. Comparison with dispersive liquid-liquid microextraction. (United States)

    Alshana, Usama; Göğer, Nilgün G; Ertaş, Nusret


    Ultrasound-assisted emulsification microextraction and dispersive liquid-liquid microextraction were compared for extraction of ephedrine, norephedrine, and pseudoephedrine from human urine samples prior to their determination by capillary electrophoresis. Formation of a microemulsion of the organic extract with an aqueous solution (at pH 3.2) containing 10% methanol facilitated the direct injection of the final extract into the capillary. Influential parameters affecting extraction efficiency were systematically studied and optimized. In order to enhance the sensitivity further, field-amplified sample injection was applied. Under optimum extraction and stacking conditions, enrichment factors of up to 140 and 1750 as compared to conventional capillary zone electrophoresis were obtained resulting in limits of detection of 12-33 μg/L and 1.0-2.8 μg/L with dispersive liquid-liquid microextraction and ultrasound-assisted emulsification microextraction when combined with field-amplified sample injection. Calibration graphs showed good linearity for urine samples by both methods with coefficients of determination higher than 0.9973 and percent relative standard deviations of the analyses in the range of 3.4-8.2% for (n = 5). The results showed that the use of ultrasound to assist microextraction provided higher extraction efficiencies than disperser solvents, regarding the hydrophilic nature of the investigated analytes.

  6. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole. (United States)

    Rodrigues, G; Becker, R; Hamm, R W; Baskaran, R; Kanjilal, D; Roy, A


    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged (238)U(40+) (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  7. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, G., E-mail:; Kanjilal, D.; Roy, A. [Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi (India); Becker, R. [Institut fur Angewandte Physik der Universitaet, D-60054 Frankfurt/M (Germany); Hamm, R. W. [R and M Technical Enterprises, Inc., 4725 Arlene Place, Pleasanton, California 94566 (United States); Baskaran, R. [Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamilnadu (India)


    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged {sup 238}U{sup 40+} (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  8. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole (United States)

    Rodrigues, G.; Becker, R.; Hamm, R. W.; Baskaran, R.; Kanjilal, D.; Roy, A.


    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged 238U40+ (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  9. An improved method for the determination of 5-hydroxymethylfurfural in Shenfu injection by direct analysis in real time-quadrupole time-of-flight mass spectrometry. (United States)

    Gao, Wen; Qi, Lian-Wen; Liu, Charles C; Wang, Rui; Li, Ping; Yang, Hua


    The emergence of direct analysis in real time (DART) ion source provides the great possibility for rapid analysis of hazardous substance in drugs. DART mass spectrometry (DART-MS) enabled the conducting of a fast and non-contact analysis of various samples, including solid or liquid ones, without complex sample preparation or chromatographic separation. In this study, a modified DART-quadrupole time-of-flight mass spectrometry (DART-QTOF-MS) method was developed for identification and determination of 5-hydroxymethylfurfural (5-HMF) in Shenfu (SF) injection. The quantitative transfer of sample solution was introduced to the glass tips of DIP-it sampler at a fixed volume, which significantly increases the repeatability and accuracy of analytical results. The protonated ion of dibutyl phthalate in the atmosphere was used as the reference mass for TOF-MS recalibration during the data acquisition for constant high accuracy mass measurements. Finally, the developed DART-MS method was used to determine 5-HMF in seven batches of SF injection, and the contents of 5-HMF were not higher than 100 µg/mL. The results obtained were further confirmed by an ultra-high performance liquid chromatography combined with triple quadrupole mass spectrometer (UHPLC-QQQ-MS). The overall results demonstrated that the DART-QTOF-MS method could be applied as an alternative technique for rapid monitoring 5-HMF in herbal medicine injection. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. (United States)

    Horie, Masafumi; Sekiya, Ichiro; Muneta, Takeshi; Ichinose, Shizuko; Matsumoto, Kenji; Saito, Hirohisa; Murakami, Takashi; Kobayashi, Eiji


    Osteoarthritis in the knees, which can be caused by meniscal defect, constitutes an increasingly common medical problem. Repair for massive meniscal defect remains a challenge owing to a lack of cell kinetics for the menisci precursors in knee joint. The synovium plays pivotal roles during the natural course of meniscal healing and contains mesenchymal stem cells (MSCs) with high chondrogenic potential. Here, we investigated whether intra-articular injected synovium-MSCs enhanced meniscal regeneration in rat massive meniscal defect. To track the injected cells, we developed transgenic rats expressing dual luciferase (Luc) and LacZ. The cells derived from synovium of the rats demonstrated colony-forming ability and multipotentiality, both characteristics of MSCs. Hierarchical clustering analysis revealed that gene expression of meniscal cells was closer to that of synovium-MSCs than to that of bone marrow-MSCs. Two to 8 weeks after five million Luc/LacZ+ synovium-MSCs were injected into massive meniscectomized knee of wild-type rat, macroscopically, the menisci regenerated much better than it did in the control group. After 12 weeks, the regenerated menisci were LacZ positive, produced type 2 collagen, and showed meniscal features by transmission electron microscopy. In in-vivo luminescence analysis, photons increased in the meniscus-resected knee over a 3-day period, then decreased without detection in all other organs. LacZ gene derived from MSCs could not be detected in other organs except in synovium by real-time PCR. Synovium-MSCs injected into the massive meniscectomized knee adhered to the lesion, differentiated into meniscal cells directly, and promoted meniscal regeneration without mobilization to distant organs.

  11. Etudes théoriques et expérimentales de la combustion dans les moteurs Diesel d'automobiles à injection directe et à préchambre Theoretical and Experimental Research on Combustion in Diesel Automotive Engines with Direct Injection and a Prechamber

    Directory of Open Access Journals (Sweden)

    Douaud A.


    Full Text Available Certaines techniques récemment développées pour la modélisation mathématique et les investigations expérimentales sur moteur Diesel sont présentées. On insiste sur l'importance de la validation croisée entre calcul et mesure. Taux d'injection, aérodynamique interne, développement du spray sont analysés en relation avec la géométrie des chambres de combustion. Des exemples, portant principalement sur des considérations de rendement énergétiques et d'émissions polluantes sont présentés à la fois sur le moteur Diesel à préchambre et le moteur Diesel à injection directe. Various techniques developed recently for the mathematical modeling and experimental investigating of diesel engines are described. Emphasis is placed on the importance of crosschecking between computing and measuring. The injection rate, internal aerodynamics and spray development are analyzed in relation to the geometry of combustion chambers. Examples mainly concerning matters of energy efficiency and pollutant emissions are given for diesel engines both with a prechamber and with direct injection.

  12. Simultaneous determination of fluoroquinolones in environmental water by liquid chromatography-tandem mass spectrometry with direct injection: A green approach. (United States)

    Denadai, Marina; Cass, Quezia Bezerra


    This work describes an on-line multi-residue method for simultaneous quantification of ciprofloxacin, enrofloxacin, gemifloxacin, moxifloxacin, norfloxacin and ofloxacin in superficial and wastewater samples. For that, an octyl restricted-access media bovine serum albumin column (RAM-BSA C8) was used for sample clean-up, enrichment and analysis with quantitation carried out by tandem mass spectrometry. For water samples volumes of only 500μL the method provided good selectivity, extraction efficiency, accuracy, and precision with quantification limits in the order of 20-150ngL(-1). Out of the six fluoroquinolones only ciprofloxacin (195ngL(-1)) and norfloxacin (270ngL(-1)) were quantified in an influent sample of the wastewater treatment plant (WWTP) of São Carlos (SP, Brazil). None were found in the superficial water samples analyzed. The capability of injecting native sample in an automated mode provides high productivity and represents a greener approach in environmental sample analysis. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Role of direct laser acceleration in energy gained by electrons in a laser wakefield accelerator with ionization injection

    CERN Document Server

    Shaw, J L; Vafaei-Najafabadi, N; Marsh, K A; Lemos, N; Mori, W B; Joshi, C


    We have investigated the role that the transverse electric field of the laser plays in the acceleration of electrons in a laser wakefield accelerator (LWFA) operating in the quasi-blowout regime through particle-in-cell code simulations. In order to ensure that longitudinal compression and/or transverse focusing of the laser pulse is not needed before the wake can self-trap the plasma electrons, we have employed the ionization injection technique. Furthermore, the plasma density is varied such that at the lowest densities, the laser pulse occupies only a fraction of the first wavelength of the wake oscillation (the accelerating bucket), whereas at the highest density, the same duration laser pulse fills the entire first bucket. Although the trapped electrons execute betatron oscillations due to the ion column in all cases, at the lowest plasma density they do not interact with the laser field and the energy gain is all due to the longitudinal wakefield. However, as the density is increased, there can be a sig...

  14. Current-injected light emission of epitaxially grown InAs/InP quantum dots on directly bonded InP/Si substrate (United States)

    Matsumoto, Keiichi; Zhang, Xinxin; Kishikawa, Junya; Shimomura, Kazuhiko


    Current-injected light emission was confirmed for metal organic vapor phase epitaxy (MOVPE) grown (Ga)InAs/InP quantum dots (QDs) on directly bonded InP/Si substrate. The InP/Si substrate was prepared by directly bonding of InP thin film and a Si substrate using a wet-etching and annealing process. A p-i-n LED structure including Stranski-Krastanov (Ga)InAs/InP QDs was grown by MOVPE on an InP/Si substrate. No debonding between Si substrate and InP layer was observed, even after MOVPE growth and operation of the device under continuous wave conditions at RT. The photoluminescence, current/voltage, and electroluminescence characteristics of the device grown on the InP/Si substrate were compared with reference grown on an InP substrate.

  15. Crude oil burning mechanisms

    DEFF Research Database (Denmark)

    van Gelderen, Laurens; Malmquist, L.M.V.; Jomaas, Grunde


    In order to improve predictions for the burning efficiency and the residue composition of in-situ burning of crude oil, the burning mechanism of crude oil was studied in relation to the composition of its hydrocarbon mixture, before, during and after the burning. The surface temperature, flame...... to the predictions of four conceptual models that describe the burning mechanism of multicomponent fuels. Based on the comparisons, hydrocarbon liquids were found to be best described by the Equilibrium Flash Vaporization model, showing a constant gas composition and gasification rate. The multicomponent fuels...... followed the diffusion-limited gasification model, showing a change in the hydrocarbon composition of the fuel and its evaporating gases, as well as a decreasing gasification rate, as the burning progressed. This burning mechanism implies that the residue composition and burning efficiency mainly depend...

  16. Evaluating the physiological state of maize (Zea mays L.) plants by direct-injection electrospray mass spectrometry (DIESI-MS). (United States)

    García-Flores, Martín; Juárez-Colunga, Sheila; Montero-Vargas, Josaphat Miguel; López-Arciniega, Janet Ana Isabel; Chagolla, Alicia; Tiessen, Axel; Winkler, Robert


    Climatic change is an increasing challenge for agriculture that is driving the development of suitable crops in order to ensure supply for both human nutrition and animal feed. In this context, it is increasingly important to understand the biochemical responses of cells to environmental cues at the whole system level, an aim that is being brought closer by advances in high throughput, cost-efficient plant metabolomics. To support molecular breeding activities, we have assessed the economic, technical and statistical feasibility of using direct mass spectrometry methods to evaluate the physiological state of maize (Zea mays L.) plants grown under different stress conditions.

  17. Learn Not To Burn. (United States)

    English, Nancy; Hendricks, Charlotte M.


    Describes the "Learn Not to Burn Preschool Program," a low-cost fire safety awareness and burn prevention curriculum for young children. The program promotes eight burn prevention methods--including practicing an escape plan--using developmentally appropriate learning objectives to increase children's fire safety knowledge, skill, and…

  18. Economics of pediatric burns. (United States)

    Bass, Michael J; Phillips, Linda G


    Sustaining a burn injury sets in motion a cycle of pain, disfigurement, and a search for survival. In pediatric burns, the injury extends to the parents where fear, ignorance, and helplessness forever change their lives. Pediatric burn injuries are caused by fire, hot liquids, clothing irons, hair curlers, caustic substances like drain cleaner, the grounding of an electrical source, and exposure to radiation. Efficiency in the delivery of pediatric burn care is critical. Maximizing resource utilization means continual self-evaluation and economic analysis of therapeutic modalities. Griffiths et al found that most childhood burns are due to scalds, which can be treated for $1061 per percent burn. Paddock et al reduced the cost of treating superficial pediatric burns and reduced the length of stay in hospital using silver-impregnated gauze over traditional methods. Barrett et al found improved cosmesis of skin grafts using cultured epithelial autografts but at a substantially increased cost. Corpron et al showed that pediatric burn units that treat burns >10% total body surface area and operative treatment of pediatric burns regardless of size generate positive revenue. There is a paucity of evidentiary pediatric burn economic data. More research is needed to address areas of pediatric burn care inefficiency. Improving knowledge of cost in all health care endeavors will create competition and drive down expenditures.

  19. Minor burns - aftercare (United States)

    ... the burn: Use cool water, not ice. The extreme cold from ice can injure the tissue even more. If possible, especially if the burn is caused by chemicals, hold the burned skin under cool running water for 10 to 15 minutes until it ...

  20. Optimization of burn referrals

    DEFF Research Database (Denmark)

    Reiband, Hanna K; Lundin, Kira; Alsbjørn, Bjarne


    INTRODUCTION: Correct estimation of the severity of burns is important to obtain the right treatment of the patient and to avoid over- and undertriage. In this study we aimed to assess how often the guidelines for referral of burn injured patients are met at the national burn centre (NBC), Denmar...

  1. Epidemiology of burns

    NARCIS (Netherlands)

    Dokter, Jan


    The aim of this thesis is to understand the epidemiology, treatment and outcomes of specialized burn care in The Netherlands. This thesis is mainly based on historical data of the burn centre in Rotterdam from 1986, combined with historical data from the burn centres in Groningen and Beverwijk from

  2. Status of the revision of the 88/609 directive on the reduction of air pollutant emissions from large burning plants; Le point sur la revision de la Directive 88/609 relative a la reduction des emissions polluantes dans l`atmosphere, en provenance des grandes installations de combustion (GIC)

    Energy Technology Data Exchange (ETDEWEB)



    The present European 88/609 directive, which applies to burning plants with a capacity of more than 50 MW (i.e. mainly power plant boilers and industrial energy production plants), is presented; different emission level limits are fixed for new and old plants, for the three main air pollutants (sulfur dioxide, nitrogen oxides and dust). Results on emission pollution levels in 1990, following the 1988 directive are presented. Several revisions drafts have been studied, which included gas turbines, and the end of the separation between old and new plants

  3. 直喷天然气发动机燃烧效率分析%Analysis of Combustion Efficiency in Direct Injection Natural Gas Engine

    Institute of Scientific and Technical Information of China (English)

    黄佐华; 曾科; 杨中乐; 王子延


    利用快速压缩装置对直喷天然气发动机的燃烧效率进行了分析.在宽广的当量比范围内,分析了三种燃料喷射方式下和均匀混合气燃烧时的燃烧效率.结果表明,燃油喷射方式下的燃烧效率在0.2~0.9当量比范围内均具有较高的数值并与喷射方式无关;在当量比小于0.2和大于0.9时,由于CO的原因,使燃烧效率降低.均匀混合气燃烧时,燃烧效率在当量比大于0.7时较高,而当量比小于0.7时,由于很高的未燃甲烷的生成使燃烧效率损失较大.燃料喷射燃烧与均匀混合气燃烧相比,维持高燃烧效率的当量比范围宽.因未燃甲烷的生成而造成的燃烧效率的损失与喷油时刻无关,因CO造成的燃烧效率的损失随喷油滞后而增加.%Investigation of combustion efficiency of direct injection natural gas engine is carried out using a rapid compression machine. Combustion efficiency of three types of injection modes and homogeneous mixture combustion are analyzed over the wide range of equivalence ratio. The results show that in the case of fuel injection modes,high combustion efficiency is observed when the equivalence ratio is in the range from 0.2 to 0.9 regardless of fuel injection modes.Obvious loss of combustion efficiency occurs when φ<0.2 and φ>0.9.For homogeneous mixture combustion,high combustion efficiency is found when φ>0.7 and large reduction of combustion efficiency occurs when φ<0.7 due to the higher unburned methane caused by bulk quenching. Fuel injection maintains high combustion efficiency over the wide range of equivalence ratio compared with that of homogeneous mixture combustion.The study also shows that little influence of unburned methane on the loss of combustion efficiency is observed with fuel injection timing but the reduction of combustion efficiency is found in the case of late injection timing.

  4. Determination of As, Cd, Pb, and Hg in urine using inductively coupled plasma mass spectrometry with the direct injection high efficiency nebulizer (United States)

    Minnich, Michael G.; Miller, Derek C.; Parsons, Patrick J.


    The application of the large-bore direct injection high efficiency nebulizer (LB-DIHEN) for the determination of arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg) in urine by inductively coupled plasma mass spectrometry (ICP-MS) is described. The LB-DIHEN is compared with the standard method using a concentric pneumatic nebulizer and cyclonic spray chamber. In addition to the toxicological significance of As, Cd, Pb, and Hg, these elements represent a cross-section of analytical issues including spectral interferences (e.g., 40Ar 35Cl + on 75As + and 98Mo 16O + on 114Cd +) and memory effects (Hg). In this study, the low sample consumption of the LB-DIHEN is used to reduce the volume of urine needed for analysis, and to reduce the volume of final diluted sample required for analysis. Eliminating the spray chamber and reducing the dead volume of the nebulizer reduces memory effects, especially for analytes such as Hg. The Dynamic Reaction Cell (DRC) is used in this study to attenuate the background level of ArCl + in spite of the increase in the solvent load and, in turn, the urine matrix (chloride) delivered to the plasma by the LB-DIHEN. This is the first report on coupling the LB-DIHEN to a standard autosampler for unattended sample analysis. The robustness of direct injection nebulization for routine analysis and the issues associated with automation of the sample introduction process are discussed. Although the figures of merit (sensitivity, limit of detection, and precision) determined for both nebulizers are slightly poorer for the LB-DIHEN than for the concentric pneumatic nebulizer, there is not a clinically significant difference between the results for both sample introduction systems. The accuracy of results is assessed using archived urine materials that are circulated by several different proficiency testing (PT) programs and external quality assessment schemes (EQAS). Results obtained using the LB-DIHEN were within the acceptable range

  5. Dielectric measurement in experimental burns: a new tool for burn depth determination? (United States)

    Papp, Anthony; Lahtinen, Tapani; Härmä, Markku; Nuutinen, Jouni; Uusaro, Ari; Alhava, Esko


    There has been a lack of methods to provide quantitative information of local tissue edema after burn injury. Noninvasive dielectric measurements provide this information. The measured value, the dielectric constant, is directly related to the amount of water in tissue. Using probes of different sizes, the measurements give information from different tissue depths. The aim of this study was to characterize edema formation at different tissue depths and to examine whether the dielectric measurements could be used to distinguish partial- and full-thickness burns in pigs. An experimental animal study with pigs (n = 6) was performed in which dielectric measurements were taken of superficial, partial-thickness, and full-thickness burns for 72 hours. There was an increase in tissue water content in the superficial dermis in the partial-thickness burns at 48 hours. In whole dermis, the superficial burns resulted in increased tissue water content at 8 hours, and the partial-thickness burns resulted in increased tissue water content at 8, 24, and 72 hours. In deep burns, the water content was significantly decreased in the superficial dermis at 24 hours. All burns resulted in a considerable increase in fat water content. The dielectric probes could be used to differentiate partial- and full-thickness burns as early as 8 hours after burn. Receiver operating curve analysis of the measurements indicated 70 to 90 percent sensitivity and 80 to 100 percent specificity after 8 hours. The dielectric measurements provide a sensitive and noninvasive method for examining tissue edema and differentiate partial- and full-thickness burns in experimental burns. Thus, they are of clinical interest for early burn depth determination.

  6. Partial Burn Laws in Propellant Erosive Burning

    Directory of Open Access Journals (Sweden)

    S.V. Finjakov


    Full Text Available Experimental and computer methods were developed for investigating the combustion phenomena in the propellants which burn in streams of hot gas flowing along the burn surfaces of the propellants. The experimental investigations allowed establishment of different dependencies for erosive burning. Computer solutions of the problem for double-base (DB propellants showed a good agreement with the experimental results. The suggested variant of modified theory considers the change of heat release in solids, the real burn surface roughness, the nonisothermality of boundary layer and the effect of gas mass blow from the propellant burn surface into the gas stream. This modified theory was used for studying burn laws at 30-1000 atm and up to gas stream sound velocities for different DB propellants. It was found that gas stream leads to splitting of the propellant burn laws, m = bp/sup v/. Pressure power (v, in this case depends on gas stream velocity (W, diameter of the propellant tube canal (d and gas stream temperature (T/sub w/. It is because of this that these burn laws were named partial burn laws. They have the form (m = bp/sup w(omega/ w,d,T/sub w/ -const. The dependencies w(omega = f(w,d,T/sub w/ were obtained by the modified theory. It was found that omega values mainly decrease when pressure increases beginning from ~200 to 400 atm and they can decrease up to w(omega = 0,1- 0,3. Similar results can be obtained for composite propellants.

  7. Direct automatic determination of bitterness and total phenolic compounds in virgin olive oil using a pH-based flow-injection analysis system. (United States)

    Garcia-Mesa, José A; Mateos, Raquel


    Flavor and taste are sensorial attributes of virgin olive oil (VOO) highly appreciated by consumers. Among the organoleptic properties of VOO, bitterness is related to the natural phenolic compounds present in the oil. Sensorial analysis is the official method to evaluate VOO flavor and bitterness, which requires highly specialized experts. Alternatively, methods based on physicochemical determinations could be useful for the industry. The present work presents a flow-injection analysis system for the direct automatic determination of bitterness and total phenolic compounds in VOO without prior isolation, based on the spectral shift undergone by phenolic compounds upon pH variation. This system enables a complete automation of the process, including dilution of the sample and its sequential injection into buffer solutions of acidic and alkaline pH. The variation of the absorbance at 274 nm showed a high correlation with bitterness and the total phenolic content of VOO, due to the close relationship between these two parameters. Thus, the proposed method determines the bitterness and phenolic compounds, with results similar to those from reference methods (relative errors ranging from 1% to 8% for bitterness and from 2% and 7% for phenolic compounds). The precision evaluated at two levels of both parameters ranged between 0.6% and 1.5% for bitterness and between 0.7% and 2.6% for phenolic compounds.

  8. Experimental Investigation on Small Break Loss of Coolant Accident for Direct Vessel Injection Line%DVI管小破口失水事故实验研究

    Institute of Scientific and Technical Information of China (English)

    彭传新; 张妍; 黄志刚; 昝元锋; 卓文彬; 闫晓


    在模块化小型反应堆非能动安全系统综合模拟实验装置上进行了压力容器直接注入(DVI)管小破口失水事故实验,研究了DVI管小破口失水事故过程中的热工水力现象和非能动安全系统运行特性。研究结果表明:模块化小型反应堆DVI管小破口失水事故中,非能动安全系统可对堆芯进行注水,有效导出堆芯衰变热量,保护堆芯安全。%T he small break loss of coolant accident (SBLOCA ) experiment for direct vessel injection (DVI ) line , w hich investigated the thermal‐hydraulic phenomena and the performances of passive safety system during the accident ,was performed on the passive safety system test facility for small modular reactor .The experimental results show that the passive safety system of small modular reactor can provide effective cool‐ant injection ,successful removal of core residual heat under the DVI line SBLOCA and protection to reactor core safety .

  9. BMW V8 gasoline engine with turbocharging, direct injection and fully variable valve gear; V8-Ottomotor von BMW mit zwei Turboladern, Direkteinspritzung und vollvariablem Ventiltrieb

    Energy Technology Data Exchange (ETDEWEB)

    Schopp, Johann; Duengen, Rainer; Fach, Heiko [BMW Group, Muenchen (Germany); Schuenemann, Erik


    In July 2012, BMW has launched its new V8 gasoline engine with so-called TwinPower Turbo technology, including turbocharging, direct injection and fully variable valve gear Valvetronic. The main objectives were to achieve a significant reduction in fuel consumption and a moderate increase in power output, to derive a 4.0-l engine-capacity version, as well as to ensure high process commonality with the new BMW M5 engine simultaneously developed by BMW M GmbH which uses a virtually identical basic engine. It was first deployed simultaneously in the new 6 Series Gran Coupe, the 5 Series Gran Turismo, the 6 Series and the revised 7 Series. (orig.)

  10. A Comparative Study of Engine Performance and Exhaust Emissions Characteristics of Linseed Oil Biodiesel Blends with Diesel Fuel in a Direct Injection Diesel Engine (United States)

    Salvi, B. L.; Jindal, S.


    This paper is aimed at study of the performance and emissions characteristics of direct injection diesel engine fueled with linseed oil biodiesel blends and diesel fuel. The comparison was done with base fuel as diesel and linseed oil biodiesel blends. The experiments were conducted with various blends of linseed biodiesel at different engine loads. It was found that comparable mass fraction burnt, better rate of pressure rise and BMEP, improved indicated thermal efficiency (8-11 %) and lower specific fuel consumption (3.5-6 %) were obtained with LB10 blend at full load. The emissions of CO, un-burnt hydrocarbon and smoke were less as compared to base fuel, but with slight increase in the emission of NOx. Since, linseed biodiesel is renewable in nature, so practically negligible CO2 is added to the environment. The linseed biodiesel can be one of the renewable alternative fuels for transportation vehicles and blend LB10 is preferable for better efficiency.


    Directory of Open Access Journals (Sweden)



    Full Text Available Biomass derived fuels are preferred as alternative fuels for IC engine due to its abundant availability and renewable nature. In the present work the performance, emission and combustion characteristics of a single cylinder constant speed , direct injection diesel engine using methyl ester of sun flower oil – eucalyptus oil blend as an alternative fuel were studied and the results are compared with thestandard diesel fuel operation. Result indicated that 50% reduction in smoke, 34% reduction in HC emission and a 37.5% reduction in CO emission for the MeS50Eu50 blend with 2.8 % increase in NOx emission at full load. Brake thermal efficiency was increased 2.7 % for eS50Eu50 blend.

  12. Simultaneous enantioselective quantification of fluoxetine and norfluoxetine in human milk by direct sample injection using 2-dimensional liquid chromatography-tandem mass spectrometry. (United States)

    Alvim-Jr, Joel; Lopes, Bianca Rebelo; Cass, Quezia Bezerra


    A two-dimensional liquid chromatography system coupled to triple quadrupole tandem mass spectrometer (2D LC-MS/MS) was employed for the simultaneously quantification of fluoxetine (FLX) and norfluoxetine (NFLX) enantiomers in human milk by direct injection of samples. A restricted access media of bovine serum albumin octadecyl column (RAM-BSAC18) was used in the first dimension for the milk proteins depletion, while an antibiotic-based chiral column was used in the second dimension. The results herein described show good selectivity, extraction efficiency, accuracy, and precision with limits of quantification in the order of 7.5ngmL(-1)for the FLX enantiomers and 10.0ngmL(-1) for NFLX enantiomers. Furthermore, it represents a practical tool in terms of sustainability for the sample preparation of such a difficult matrix.

  13. Effect of L-ascorbic acid as additive for exhaust emission reduction in a direct injection diesel engine using mango seed methyl ester

    Directory of Open Access Journals (Sweden)

    Ramalingam Senthil


    Full Text Available In this present study the effect of L-ascorbic acid antioxidants additive for oxides of nitrogen emission reduction in a neat mango seed biodiesel fueled direct injection Diesel engine. The antioxidant additive L-ascorbic acid is tested on a Kirloskar-make four stroke water cooled single cylinder Diesel engine of 5.2 kW. There are four proportions of additive are used:1 ml, 2 ml, 3 ml, and 4 ml. Among the different additive proportion,4 ml concentration of L-ascorbic acid additive is optimal as oxides of nitrogen levels are substantially reduced up to 9% in the whole load range in comparison with neat biodiesel. However, hydrocarbon and carbonmonoxide emissions are found to have slightly increased by the addition of additive with biodiesel.

  14. [Effects of teaching method using standardized patients on nursing competence in subcutaneous injection, self-directed learning readiness, and problem solving ability]. (United States)

    Eom, Mi-Ran; Kim, Hyun-Sook; Kim, Eun-Kyung; Seong, Kayeon


    The purpose of this study was to evaluate the effects of teaching method using Standardized Patients (SPs) on nursing competence, self-directed learning readiness, and problem solving ability-focusing on subcutaneous insulin injection. This research was a nonequivalent control group non-synchronized post-test design. The subjects consisted of 62 junior nursing students at E University. Scenarios to train SPs and checklists to evaluate the students' competence were developed by our research team. The experimental group (n=31) participated in the teaching class using SPs. The control group (n=31) received traditional practice education. The collected data were analyzed with descriptive analysis, X(2)/Fisher's exact test, t-test, Pearson's correlation coefficient, and Cronbach's alpha using SPSS WIN 14.0 Program. The mean scores of competence, self-directed learning readiness, and problem solving were significantly higher in the experimental group than the control group. As confirmed by this research findings, the teaching method using SPs was more effective than the traditional method to improve junior nursing students' competence, self-directed learning readiness, and problem solving. Therefore, It is necessary to develop a various of scenarios and to testify their effectiveness.

  15. Direct Injection LC-MS-MS Analysis of Opiates, Methamphetamine, Buprenorphine, Methadone and Their Metabolites in Oral Fluid from Substitution Therapy Patients. (United States)

    Liu, Hsiu-Chuan; Lee, Hsi-Tzu; Hsu, Ya-Ching; Huang, Mei-Han; Liu, Ray H; Chen, Tai-Jui; Lin, Dong-Liang


    A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS-MS) method was developed, validated and applied to simultaneous analysis of oral fluid samples for the following 10 analytes: methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), buprenorphine, norbuprenorphine, morphine, codeine, 6-acetylmorphine, 6-acetylcodeine, amphetamine, and methamphetamine. The oral fluid sample was briefly centrifuged and the supernatant was directly injected into the LC-MS-MS system operated under reverse-phase chromatography and electrospray ionization (ESI). Deuterated analogs of the analytes were adopted as the internal standards and found to be effective (except for buprenorphine) to compensate for potential matrix effects. Each analytical run took 0.99) established for buprenorphine and the other nine analytes were 5-100 and 1-100 ng/mL. Intra- and interday precision (% CV) ranges for the 10 analytes were 0.87-12.2% and 1.27-12.8%, while the corresponding accuracy (%) ranges were 91.8-113% and 91.9-111%. Limits of detection and quantitation established for these 10 analytes were in the ranges of 0.1-1.0 and 0.25-1.0 ng/mL (5 ng/mL for buprenorphine). The method was successfully applied to the analysis of 62 oral fluid specimens collected from patients participating in methadone and buprenorphine substitution therapy programs. Analytical results of methadone and buprenorphine were compared with data derived from GC-MS analysis and found to be compatible. Overall, the direct injection LC-MS-MS method performed well, permitting rapid analysis of oral fluid samples for simultaneous quantification of methadone, buprenorphine, opiate and amphetamine drug categories without extensive sample preparation steps.

  16. Medroxyprogesterone Injection (United States)

    Medroxyprogesterone intramuscular (into a muscle) injection and medroxyprogesterone subcutaneous (under the skin) injection are used to prevent pregnancy. Medroxyprogesterone subcutaneous injection is also used to treat endometriosis (a condition in which ...

  17. Pentamidine Injection (United States)

    Pentamidine injection is used to treat pneumonia caused by a fungus called Pneumocystis carinii. It is in ... Pentamidine injection comes as powder to be mixed with liquid to be injected intramuscularly (into a muscle) ...

  18. Piezoelectric Injection Systems (United States)

    Mock, R.; Lubitz, K.

    The origin of direct injection can be doubtlessly attributed to Rudolf Diesel who used air assisted injection for fuel atomisation in his first self-ignition engine. Although it became apparent already at that time that direct injection leads to reduced specific fuel consumption compared to other methods of fuel injection, it was not used in passenger cars for the moment because of its disadvantageous noise generation as the requirements with regard to comfort were seen as more important than a reduced specific consumption.

  19. [The pain from burns]. (United States)

    Latarjet, J


    The painful events associated with the treatment of a severe burn can, because of their long-lasting and repetitive characteristics, be one of the most excruciating experiences in clinical practice. Moreover, burn pain has been shown to be detrimental to burn patients. Although nociception and peripheral hyperalgesia are considered the major causes of burn pain, the study of more hypothetical mechanisms like central hyperalgesia and neuropathic pain may lead to a better understanding of burn pain symptoms and to new therapeutic approaches. Continuous pain and intermittent pain due to therapeutic procedures are two distinct components of burn pain. They have to be evaluated and managed separately. Although continuous pain is by far less severe than intermittent pain, the treatment is, in both cases, essentially pharmacological relying basically on opioids. Because of wide intra- and inter-individual variations, protocols will have to leave large possibilities of adaptation for each case, systematic pain evaluation being mandatory to achieve the best risk/benefit ratio. Surprisingly, the dose of medication decreases only slowly with time, a burn often remaining painful for long periods after healing. Non pharmacological treatments are often useful and sometimes indispensable adjuncts; but their rationale and their feasibility depends entirely on previous optimal pharmacological control of burn pain. Several recent studies show that burn pain management is inadequate in most burn centres.

  20. 75 FR 65482 - Approval of a Petition for Exemption From Hazardous Waste Disposal Injection Restrictions to... (United States)


    ... (code K062 under 40 CFR part 261), into one Class I hazardous waste injection well specifically... AGENCY Approval of a Petition for Exemption From Hazardous Waste Disposal Injection Restrictions to... ArcelorMittal Burns Harbor, LLC (AMBH) of Burns Harbor, Indiana, for three Class I injection wells located...

  1. Rehabilitation of the Burned Hand (United States)


    13 Mallet and swan-neck deformities Thermal injury to the terminal slip of the extensor tendon can result in loss of DIP joint extension or mallet...deformity. Injury to the terminal slip can be a result of direct thermal injury or tendon ischemia induced as the injured tendon is compressed between...elastic bandage or self-adherent wrap may be necessary. Cotton socks over the splint may prevent the child from removing the splint. Contact burns

  2. Regimes Of Helium Burning

    CERN Document Server

    Timmes, F X


    The burning regimes encountered by laminar deflagrations and ZND detonations propagating through helium-rich compositions in the presence of buoyancy-driven turbulence are analyzed. Particular attention is given to models of X-ray bursts which start with a thermonuclear runaway on the surface of a neutron star, and the thin shell helium instability of intermediate-mass stars. In the X-ray burst case, turbulent deflagrations propagating in the lateral or radial directions encounter a transition from the distributed regime to the flamlet regime at a density of 10^8 g cm^{-3}. In the radial direction, the purely laminar deflagration width is larger than the pressure scale height for densities smaller than 10^6 g cm^{-3}. Self-sustained laminar deflagrations travelling in the radial direction cannot exist below this density. Similarily, the planar ZND detonation width becomes larger than the pressure scale height at 10^7 g cm^{-3}, suggesting that a steady-state, self-sustained detonations cannot come into exista...

  3. Burns and epilepsy. (United States)

    Berrocal, M


    This is a report of the first descriptive analytic study of a group of 183 burn patients, treated in the Burn Unit at the University Hospital of Cartagena, Colombia during the period since January 1985 until December 1990. There is presented experience with the selected group of 24 patients in whom the diagnosis of burn was associated with epilepsy. There is also analysed and described the gravity of the scars sequels, neurological disorders, the complication of the burn and an impact of this problem on the patient, his (her) family and the community. It is very important to report that there was found Neurocisticercosis in 66.6% of the group of burn patients with epilepsy, and it is probably the first risk factor of burn in this group.

  4. Burn Control of Magnetically Confined Fusion Plasma 2. Burn Control in Tokamak Fusion Reactors 2.3 Burn Control in ITER (United States)

    Fujisawa, Noboru

    The issue of burn control in FDR-ITER, the design of which was completed in 1998, is introduced, Controllability was studied based on the ID transport code, PRETOR, during the burn phase with self-ignition, as well as during start-up and shut-down. The results of the present study have helped us to identify the importance of controlling the fuel supply, impurity injection, and heating power to maintain fusion power and power to the divertor.

  5. The Burning Saints

    DEFF Research Database (Denmark)

    Xygalatas, Dimitris

    . Carrying the sacred icons of the saints, participants dance over hot coals as the saint moves them. The Burning Saints presents an analysis of these rituals and the psychology behind them. Based on long-term fieldwork, The Burning Saints traces the historical development and sociocultural context......, The Burning Saints presents a highly original analysis of how mental processes can shape social and religious behaviour....

  6. Management of Hand Burns

    Directory of Open Access Journals (Sweden)

    Fatih Irmak


    Full Text Available Objective: The hand is one of the most frequently affected body parts by burn injuries with a rate of 80% among all burn wounds. Early and effective treatment ensures the best chance of survival as well as a good functional prognosis. The aim of this study was to determine the epidemiology, variation, relationship between etiology and hospital stay, clinical features, and management of hand burns. Material and Methods: This retrospective study was conducted the University of Health Sciences; Şişli Hamidiye Etfal Application and Research Center, Departmant of Plastic, Reconstructive and Aesthetic Surgery and the Intensive Burn Care Unit between April 2009 and April 2014. Burns were assessed based on etiology, anatomical location, percentage of total body surface area affected, and depth of injury. Treatment was categorized as conservative, elective operative, or urgent operative. Results: In the study period, 788 patients were admitted to our Burn Unit. Of these, 240 were females (30.5% and 548 were males (69.5%. The most common type of burn injury in this study was thermal injury (695 cases; 88.2%, followed by electrical injury (67 cases; 8.5%, and chemical, frictional or unknown injuries (26 cases; 3.3%. Majority (more than 85% of the patients had second-degree burns, and some had third-degree burns. Conclusions: Burns commonly affect the hands, and many functional problems may develop if appropriate basic treatments are neglected. The best treatment for burns is prevention. Appropriate indoor arrangement and simple but effective measures that can be taken at home can significantly reduce burn trauma exposure.

  7. Management of Outpatient Burns


    Waslen, G. D.


    The severity of burns depends on the depth and extent of body surface involved. The total body surface area (TBSA) involved can be estimated by the ‘rule of nines’; body locations are 9% of body surface or multiples of nine. Depth and TBSA can be used to classify burns as minor, moderate, or critical. Diagnosis depends on history and physical examination. Most burns can be treated in an outpatient setting. Treatment should include debriding necrotic tissue, preventing infection and encouragin...

  8. Improvement of emissions and performance by using of air jet, exhaust gas re-circulation and insulation methods in a direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Jafarmadara S.


    Full Text Available This article investigates the improvement of operation characteristics and emissions reduction by means of creating an air-cell inside the piston body, exhaust gases recirculating and insulating combustion chamber in a direct injection diesel engine simultaneously. The engine considered is a caterpillar 3401 which was modeled with an air-cell included as part of the piston geometry. This air-cell demonstrates that air injection in late combustion period can be effective in a significant reduction of Soot emission while cold EGR can be effective in reduction of NOx emission. Also for increasing of performance parameters, combustion chamber with air-cell is insulated. The analyses are carried out at part (75% of full load and full load conditions at the same engine speed 1600 rpm. The obtained results indicate that creating the air-cell has a slight effect on improvement of performance parameters and it has significantly effect on Soot reduction. The air-cell decreases the Soot pollutant as a factor of two at both part and full load conditions. Also, the adding 5% of cold EGR in inlet air decreases NOx by about half and insulating the engine increases the power and IMEP by about 7.7% and 8.5% and decreases the ISFC by about 7.5% at part load and increases power and IMEP by 8.5%, 8.5% and decreases ISFC by 8% at full load condition, respectively. Using this method, it was possible to control emissions formation and increase performance parameters simultaneously. The predicted results for mean in-cylinder pressure and emissions are compared to the corresponding experimental results and show good agreements.

  9. Advanced optical diagnostics applied to a multi-cylinder engine with gasoline direct injection; Weiterentwicklung der Visualisierungsmethodik am Beispiel eines Mehrzylindermotors mit Benzindirekteinspritzung

    Energy Technology Data Exchange (ETDEWEB)

    Alt, M.; Eberle, F.; Schaffner, P.; Quarg, J. [Opel Powertrain GmbH, Ruesselsheim (Germany)


    The development of modern combustion processes requires a more intensive use of simulation and optical measuring methods. When the combustion method of an engine concept has been determined and subsequently applied to one or more engines, the following development steps usually do not include the optical access. But in this phase of multicylinder engine development, too, an optical evaluation of the combustion processes provides important information. Especially regarding problems of time, the optical data can help to adopt the right solution and check it for its effect more easily. In this way the videoscopy offers a significant tool to optimize today's engines. The techniques of visualizing the Otto engine related combustion are continuously advanced. The resolution of quickacting CCD cameras has been improved considerably while at the same time reducing the exposure time. Both the injection and the mixture preparation can be investigated in detail under realistic conditions. Variations in the mixture preparation from cycle to cycle can also be represented. Today's state-of-the-art cameras with amplifier can visualize the optimum sootfree combustion without the necessity of an additional light. High-speed photomultiplier cameras can record single combustion cycles with a high resolution and thus enable the analysis. The endoscopic consideration of the combustion processes is no longer restricted to the visible range of the wavelength, but constitutes a visualization of the combustion in the ultraviolet range. The example of a four-cylinder engine with gasoline direct injection demonstrates the good applicability of the videoscopy. This technique can be employed quite easily to improve the understanding of the engine processes during the development phase. (orig.)

  10. Development and testing of a novel lab-scale direct steam-injection apparatus to hydrolyse model and saline crop slurries. (United States)

    Santi, Guglielmo; Guglielmo, Santi; D'Annibale, Alessandro; Alessandro, D'Annibale; Petruccioli, Maurizio; Maurizio, Petruccioli; Crognale, Silvia; Silvia, Crognale; Ruzzi, Maurizio; Maurizio, Ruzzi; Valentini, Riccardo; Riccardo, Valentini; Moresi, Mauro; Moresi, Mauro


    In this work, a novel laboratory-scale direct steam-injection apparatus (DSIA) was developed to overcome the main drawback of the conventional batch-driven lab rigs, namely the long time needed to heat fiber slurry from room to reaction temperatures greater than 150 °C. The novel apparatus mainly consisted of three units: (i) a mechanically-stirred bioreactor where saturated steam at 5-30 bar can be injected; (ii) an automatic on-off valve to flash suddenly the reaction medium after a prefixed reaction time; (iii) a cyclone separator to recover the reacted slurry. This system was tested using 0.75 dm³ of an aqueous solution of H₂SO₄ (0.5%, v/v) enriched with 50 kg m⁻³ of either commercial particles of Avicel® and Larch xylan or 0.5 mm sieved particles of Tamarix jordanis. Each slurry was heated to about 200 °C by injecting steam at 28 bar for 90 s. The process efficiency was assessed by comparing the dissolution degree of suspended solid (Y(S)), as well as xylose (Y(X)), glucose (Y(G)), and furfural (Y(F)) yields, with those obtained in a conventional steam autoclave at 130 °C for 30 or 60 min. Treatment of T. jordanis particles in DSIA resulted in Y(S) and Y(G) values quite similar to those obtained in the steam autoclave at 130 °C for 60 min, but in a less efficient hemicellulose solubilization. A limited occurrence of pentose degradation products was observed in both equipments, suggesting that hydrolysis predominated over degradation reactions. The susceptibility of the residual solid fractions from DSIA treatment to a conventional 120 h long cellulolytic treatment using an enzyme loading of 5.4 FPU g⁻¹ was markedly higher than that of samples hydrolysed in the steam autoclave, their corresponding glucose yields being equal to 0.94 and 0.22 g per gram of initial cellulose, respectively. Thus, T. jordanis resulted to be a valuable source of sugars for bioethanol production as proved by preliminary tests in the novel lab rig developed here.

  11. Burns in pregnancy. (United States)

    Maghsoudi, Hemmat; Samnia, Roya; Garadaghi, Abasad; Kianvar, Hadi


    A 9-year prospective study of burns in pregnant women hospitalized at the Sina hospital burn center was conducted to determine the etiology and outcome of pregnant patients. Fifty-one patients (27.45% self-inflicted, 72.55% unintentional) were identified and stratified by age, burn size, presence or absence of inhalation injury, trimester of pregnancy, maternal and fetal mortality, and cause of burn. The mean patient age was 24.2 years. There were 20 maternal deaths and 23 fetal deaths. The majority of which (maternal: 13 and fetal: 13) were among self-inflicted burned pregnant women. The mean burn size was 37.7%, and was significantly larger for nonsurvivors of mother than survivors (68.8% versus 17.6%; pburned body surface area exceeds 40%, both maternal and fetal mortality reaches 100%. Inhalation injuries were strongly associated with large burns, and were presents in all suicide patients. Kerosene ignition (68.6% of all patients, 100% of self-inflicted patients) was the most common type of burn. Large burn size was the strongest predictor of mortality of mother and fetus followed by the presence of inhalation injury.

  12. 重组人生长激素联用丹参注射液治疗重症烧伤的临床研究%The Clinical Study of Effect of Recombinant Human Growth Hormone Combined with Danshen Injection in Severely Burned Patients

    Institute of Scientific and Technical Information of China (English)

    庞淑光; 叶胜捷; 张文振; 李泳焱; 方声教; 陈如俊


      目的评价重组人生长激素联合丹参注射液对重症烧伤的临床治疗效果。方法将120例严重烧伤患者,随机分为A组(观察组)和B组(对照组),每组60例。A组静脉滴注丹参注射液,B组注射相同体积的等渗盐水;两组给予皮下注射0.1mg/(kg•d)重组人生长激素治疗。疗程为14d。监测并记录两组患者的蛋白代谢及糖代谢,内毒素(LPS)、肿瘤坏死因子α(TNF-α)以及白细胞介素(IL-6)水平。结果治疗后7d与14d,观察组血红蛋白及血浆总蛋白均高于对照组,差异具有统计学意义(P<0.05);治疗后7d与14d,观察组LPS(脂多糖),TNF-α,IL=6均显著低于对照组(P<0.05)。结论重组人生长激素联用丹参注射液对重症烧伤患者可发挥一系列的治疗作用,如促进蛋白质合成,抑制炎性反应,提高患者的免疫功能,降低患者感染率,进而可缩短患者的住院时间。治疗效果稳定可靠,优于单用重组人生长激素治疗。%Objective To evaluate the clinical efficacy of recombinant human growth hormone combined with Danshen injection in severely burned patients. Methods 120 cases of severely burned patients were randomLy divided into A group (rhGH and D.I. group) and B group (control group). Patients in group A were given Danshen injection and patients in group B the same volume of normal saline. Both groups were treated with rhGH injection [0.1mg/(kg•d), subcutaneous injection]. The treatment lasted for 14 days. Protein metabolism, glucose metabolism, LPS, TNF-α, IL-6 were assayed and compared between two groups. Results Compared with patients in group B, those in group A had significantly higher protein content and remarkably lower LPS, TNF-αand IL-6 (P<0.05). Conclusions The therapy of recombinant human growth hormone combined with Danshen Injection can treat severely burned patients in a number of ways:promoting protein synthesis

  13. A novel needleless liquid jet injection methodology for improving direct cardiac gene delivery: An optimization of parameters, AAV mediated therapy and investigation of host responses in ischemic heart failure (United States)

    Fargnoli, Anthony Samuel

    Heart disease remains the leading cause of mortality and morbidity worldwide, with 22 million new patients diagnosed annually. Essentially, all present therapies have significant cost burden to the healthcare system, yet fail to increase survival rates. One key employed strategy is the genetic reprogramming of cells to increase contractility via gene therapy, which has advanced to Phase IIb Clinical Trials for advanced heart failure patients. It has been argued that the most significant barrier preventing FDA approval are resolving problems with safe, efficient myocardial delivery, whereby direct injection in the infarct and remote tissue areas is not clinically feasible. Here, we aim to: (1) Improve direct cardiac gene delivery through the development of a novel liquid jet device approach (2) Compare the new method against traditional IM injection with two different vector constructions and evaluate outcome (3) Evaluate the host response resulting from both modes of direct cardiac injection, then advance a drug/gene combination with controlled release nanoparticle formulations.

  14. GC/MS method for determining carbon isotope enrichment and concentration of underivatized short-chain fatty acids by direct aqueous solution injection of biogas digester samples. (United States)

    Mulat, Daniel Girma; Feilberg, Anders


    In anaerobic digestion of organic matter, several metabolic pathways are involved during the simultaneous production and consumption of short-chain fatty acids (SCFA) in general and acetate in particular. Understanding the role of each pathway requires both the determination of the concentration and isotope enrichment of intermediates in conjunction with isotope labeled substrates. The objective of this study was to establish a rapid and simple GC/MS method for determining the isotope enrichment of acetate and concentration of underivatized short-chain fatty acids (SCFA) in biogas digester samples by direct liquid injection of acidified aqueous samples. Sample preparation involves only acidification, centrifugation and filtration of the aqueous solution followed by direct injection of the aqueous supernatant solution onto a polar column. With the sample preparation and GC/MS conditions employed, well-resolved and sharp peaks of underivatized SCFA were obtained in a reasonably short time. Good recovery (96.6-102.3%) as well as low detection (4-7 µmol/L) and quantification limits (14-22 µmol/L) were obtained for all the 6 SCFA studied. Good linearity was achieved for both concentration and isotope enrichment measurement with regression coefficients higher than 0.9978 and 0.9996, respectively. The method has a good intra- and inter-day precision with a relative standard deviation (RSD) below 6% for determining the tracer-to-tracee ratio (TTR) of both [2-(13)C]acetate and [U-(13)C]acetate. It has also a good intra- and inter-day precision with a RSD below 6% and 5% for determining the concentration of standard solution and biogas digester samples, respectively. Acidification of biogas digester samples with oxalic acid provided the low pH required for the protonation of SCFA and thus, allows the extraction of SCFA from the complex sample matrix. Moreover, oxalic acid was the source of formic acid which was produced in the injector set at high temperature. The produced

  15. Biodiesel production from inedible animal tallow and an experimental investigation of its use as alternative fuel in a direct injection diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Oener, Cengiz [Technical Education Faculty, Automotive Division, Firat University, 23119 Elazig (Turkey); Altun, Sehmus [Technical Education Faculty, Automotive Division, Batman University, 72060 Batman (Turkey)


    In this study, a substitute fuel for diesel engines was produced from inedible animal tallow and its usability was investigated as pure biodiesel and its blends with petroleum diesel fuel in a diesel engine. Tallow methyl ester as biodiesel fuel was prepared by base-catalyzed transesterification of the fat with methanol in the presence of NaOH as catalyst. Fuel properties of methyl ester, diesel fuel and blends of them (5%, 20% and 50% by volume) were determined. Viscosity and density of fatty acid methyl ester have been found to meet ASTM D6751 and EN 14214 specifications. Viscosity and density of tallow methyl esters are found to be very close to that of diesel. The calorific value of biodiesel is found to be slightly lower than that of diesel. An experimental study was carried out in order to investigate of its usability as alternative fuel of tallow methyl ester in a direct injection diesel engine. It was observed that the addition of biodiesel to the diesel fuel decreases the effective efficiency of engine and increases the specific fuel consumption. This is due to the lower heating value of biodiesel compared to diesel fuel. However, the effective engine power was comparable by biodiesel compared with diesel fuel. Emissions of carbon monoxide (CO), oxides of nitrogen (NO{sub x}), sulphur dioxide (SO{sub 2}) and smoke opacity were reduced around 15%, 38.5%, 72.7% and 56.8%, respectively, in case of tallow methyl esters (B100) compared to diesel fuel. Besides, the lowest CO, NO{sub x} emissions and the highest exhaust temperature were obtained for B20 among all other fuels. The reductions in exhaust emissions made tallow methyl esters and its blends, especially B20 a suitable alternative fuel for diesel and thus could help in controlling air pollution. Based on this study, animal tallow methyl esters and its blends with petroleum diesel fuel can be used a substitute for diesel in direct injection diesel engines without any engine modification. (author)

  16. Burns and military clothing. (United States)

    McLean, A D


    Burn injury is a ubiquitous threat in the military environment. The risks during combat are well recognised, but the handling of fuel, oil, munitions and other hot or flammable materials during peacetime deployment and training also imposes an inherent risk of accidental burn injury. Over the last hundred years, the burn threat in combat has ranged from nuclear weapons to small shoulder-launched missiles. Materials such as napalm and white phosphorus plainly present a risk of burn, but the threat extends to encompass personnel in vehicles attacked by anti-armour weapons, large missiles, fuel-air explosives and detonations/conflagrations on weapons platforms such as ships. Large numbers of burn casualties were caused at Pearl Harbor, in Hiroshima and Nagasaki, Vietnam, during the Arab/Israeli Wars and in the Falkland Islands conflict. The threat from burns is unlikely to diminish, indeed new developments in weapons seek to exploit the vulnerability of the serviceman and servicewoman to burns. Clothing can be a barrier to some types of burn--both inherently in the properties of the material, but also by trapping air between clothing layers. Conversely, ignition of the clothing may exacerbate a burn. There is hearsay that burnt clothing products within a wound may complicate the clinical management, or that materials that melt (thermoplastic materials) should not be worn if there is a burn threat. This paper explores the incidence of burn injury, the mechanisms of heat transfer to bare skin and skin covered by materials, and the published evidence for the complication of wound management by materials. Even light-weight combat clothing can offer significant protection to skin from short duration flash burns; the most vulnerable areas are the parts of the body not covered--face and hands. Multilayered combat clothing can offer significant protection for short periods from engulfment by flames; lightweight tropical wear with few layers offers little protection. Under

  17. Critical issues in burn care. (United States)

    Holmes, James H


    Burn care, especially for serious burn injuries, represents a considerable challenge for the healthcare system. The American Burn Association has established a number of strategies for the management of burn patients and dedicates its efforts and resources to promoting and supporting burn-related research, education, care, rehabilitation, and prevention, often in collaboration with other organizations. The American Burn Association has recommended that patients with serious burns be referred to a designated burn center, ie, a hospital outfitted with specialized personnel and equipment dedicated to burn care. Burn centers have been operational for over 50 years, but the complexity and costs of providing specialized burn care have given rise to a number of critical administrative and political issues. These include logistical limitations imposed by the uneven national distribution of burn centers and a potential shortage of burn beds, both during everyday conditions and in the event of a mass disaster. Burn surgeon shortages have also been identified, stemming, in part, from a lack of specialized burn care training opportunities. There is currently a lack of quality outcome data to support evidence-based recommendations for burn care, and burn care centers are compromised by problems obtaining reimbursement for the care of uninsured and publicly insured out-of-state burn patients. Initiatives are underway to maintain efficient burn care facilities that are fully funded, easily accessible, and most importantly, provide optimal, evidence-based care on a daily basis, and are well-equipped to handle a surge of patients during a disaster situation.

  18. Numerical Study on Combustion Instability in Lean Direct Injection Combustor%贫油直喷燃烧室燃烧稳定性的数值研究

    Institute of Scientific and Technical Information of China (English)

    洪挺; 张文普


    贫油燃烧过程中很容易产生振荡燃烧现象,而振荡燃烧则会进一步影响燃烧室中氮氧化物(nitrogen oxides,NOx)的生成与排放.为了研究振荡燃烧的触发机制及其对NOx生成与排放的影响,利用FLUENT中的离散相模型、非预混燃烧模型和混合分数/PDF平衡化学反应模型,对贫油直喷燃烧室内的航空煤油/空气非预混燃烧进行了大涡数值模拟,亚网格模型采用WALE模型.将计算与实验值进行比较发现:在喷嘴附近区域,数值结果与预测结果略有差异,在其他区域,数值计算的各个物理参量值都与实验值非常吻合.通过改变入口空气流速,触发了振荡燃烧,其主频为560和1200Hz.对燃烧稳定性的模拟表明,可以通过调整燃烧室的入口条件来激励或者抑制振荡燃烧现象的出现.在此基础上分别计算了稳定燃烧和不稳定燃烧时的NOx排放,结果表明振荡燃烧现象的出现明显改变了NOx的生成与排放.%Lean direct injection(LDI) combustion increases the occurrence probability of oscillation combustion, which affects the production and emission of nitrogen oxides (Nox). In order to study the mechanism of oscillation combustion and its impact on the production and emission of Nox, Large eddy simulation (LES) was applied in FLUENT with non-premixed combustion model, discrete phase model (DPM), mixture fraction/PDF equilibrium chemistry model and WALE subgrid-scale model to simulate the combustion of kerosene and air in a lean direct injection combustor. The results are little different from that of experimental measurements in the areas near the injection, while they agree well with the experimental results in the other areas. The combustion became unstable while the inlet air velocity changed, and the oscillation frequencies were 560 Hz and 1 200 Hz. It means that combustion instability should be induced by disturbance of equivalence ratio. In addition, both in stable and unstable

  19. Pain in burn patients. (United States)

    Latarjet, J; Choinère, M


    While severe pain is a constant component of the burn injury, inadequate pain management has been shown to be detrimental to burn patients. Pain-generating mechanisms in burns include nociception, primary and secondary hyperalgesia and neuropathy. The clinical studies of burn pain characteristics reveal very clear-cut differences between continuous pain and pain due to therapeutic procedures which have to be treated separately. Some of the main features of burn pain are: (1) its long-lasting course, often exceeding healing time, (2) the repetition of highly nociceptive procedures which can lead to severe psychological disturbances if pain control is inappropriate. Pharmaco-therapy with opioids is the mainstay for analgesia in burned patients, but non-pharmacological techniques may be useful adjuncts. Routine pain evaluation is mandatory for efficient and safe analgesia. Special attention must be given to pain in burned children which remains too often underestimated and undertreated. More educational efforts from physicians and nursing staff are necessary to improve pain management in burned patients.

  20. Nutrition of burned patients. (United States)

    Gudaviciene, Daiva; Rimdeika, Rytis; Adamonis, Kestutis


    Burns form 5-12% of all traumas. About 2,200 of patients are annually hospitalized in Lithuania. In most cases people of the employable age get burned. The treatment is often long-lasting, and afterwards recovered patients often have invalidity from burn sequels. The mortality of hospitalized burned patients is about 10%. The most common causes of death are pulmonary edema, pneumonia, sepsis and multiorgan failure. All these complications are related with insufficient nutrition. These complications are extremely frequent and dangerous for patients with more than 20% of body burned. The nutritional support of burned patient gives a possibility to increase the survival probability, to decrease complication rate and hospitalization time. Currently in Lithuania there are no standards for burned patient nutrition. More attention is given to strategy of surgical strategy and techniques, as well as antibiotic therapy. This article is the review of the different aspects of artificial nutrition of burned patient: indications, modes of nutrition, mixtures and terms of nutritional support.

  1. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection. (United States)

    Li, Yongtao; Whitaker, Joshua S; McCarty, Christina L


    A large volume direct aqueous injection method was developed for the analysis of iodinated haloacetic acids in drinking water by using reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry in the negative ion mode. Both the external and internal standard calibration methods were studied for the analysis of monoiodoacetic acid, chloroiodoacetic acid, bromoiodoacetic acid, and diiodoacetic acid in drinking water. The use of a divert valve technique for the mobile phase solvent delay, along with isotopically labeled analogs used as internal standards, effectively reduced and compensated for the ionization suppression typically caused by coexisting common inorganic anions. Under the optimized method conditions, the mean absolute and relative recoveries resulting from the replicate fortified deionized water and chlorinated drinking water analyses were 83-107% with a relative standard deviation of 0.7-11.7% and 84-111% with a relative standard deviation of 0.8-12.1%, respectively. The method detection limits resulting from the external and internal standard calibrations, based on seven fortified deionized water replicates, were 0.7-2.3 ng/L and 0.5-1.9 ng/L, respectively.

  2. A Very Large Eddy Simulation of the Nonreacting Flow in a Single-Element Lean Direct Injection Combustor Using PRNS with a Nonlinear Subscale Model (United States)

    Shih, Tsan-Hsing; Liu, Nan-Suey


    Very large eddy simulation (VLES) of the nonreacting turbulent flow in a single-element lean direct injection (LDI) combustor has been successfully performed via the approach known as the partially resolved numerical simulation (PRNS/VLES) using a nonlinear subscale model. The grid is the same as the one used in a previous RANS simulation, which was considered as too coarse for a traditional LES simulation. In this study, we first carry out a steady RANS simulation to provide the initial flow field for the subsequent PRNS/VLES simulation. We have also carried out an unsteady RANS (URANS) simulation for the purpose of comparing its results with that of the PRNS/VLES simulation. In addition, these calculated results are compared with the experimental data. The present effort has demonstrated that the PRNS/VLES approach, while using a RANS type of grid, is able to reveal the dynamically important, unsteady large-scale turbulent structures occurring in the flow field of a single-element LDI combustor. The interactions of these coherent structures play a critical role in the dispersion of the fuel, hence, the mixing between the fuel and the oxidizer in a combustor.

  3. Reduction of aflatoxin B1 during tortilla production and identification of degradation by-products by direct-injection electrospray mass spectrometry

    Directory of Open Access Journals (Sweden)

    Abigail Moreno-Pedraza


    Full Text Available Objective. To determine the effect of pH, and exposure time over the inactivation of aflatoxin B1 (AFB1 during the tortilla making process as well as the degradative molecules generated. Materials and methods. Inactivation of AFB1 in maize-dough with alkaline pH and in alkaline methanolic solutions was determined by HPLC. Kinetics of time exposure of AFB1 in methanolic solution and the degradative products were analyzed by direct injection electrospray mass spectometry (DIESI-MS. Results. The alkaline pH of the maize-dough after nixtamalización between 10.2, and 30-40 minutes of resting at room temperature allows the 100% reduction of AFB1. DIESI-MS analysis of the extracts indicated the presence of two degradation molecules from AFB1. Conclusion. The alkaline pH of maize-dough and resting time are the principal factors involved in diminishing AFB1 levels in tortillas. A procedure to the tortilla making process is proposed, which allows the reduction of remnant AFB1, avoiding the accumulative effect over consumers.

  4. The gas chromatographic determination of volatile fatty acids in wastewater samples: evaluation of experimental biases in direct injection method against thermal desorption method. (United States)

    Ullah, Md Ahsan; Kim, Ki-Hyun; Szulejko, Jan E; Cho, Jinwoo


    The production of short-chained volatile fatty acids (VFAs) by the anaerobic bacterial digestion of sewage (wastewater) affords an excellent opportunity to alternative greener viable bio-energy fuels (i.e., microbial fuel cell). VFAs in wastewater (sewage) samples are commonly quantified through direct injection (DI) into a gas chromatograph with a flame ionization detector (GC-FID). In this study, the reliability of VFA analysis by the DI-GC method has been examined against a thermal desorption (TD-GC) method. The results indicate that the VFA concentrations determined from an aliquot from each wastewater sample by the DI-GC method were generally underestimated, e.g., reductions of 7% (acetic acid) to 93.4% (hexanoic acid) relative to the TD-GC method. The observed differences between the two methods suggest the possibly important role of the matrix effect to give rise to the negative biases in DI-GC analysis. To further explore this possibility, an ancillary experiment was performed to examine bias patterns of three DI-GC approaches. For instance, the results of the standard addition (SA) method confirm the definite role of matrix effect when analyzing wastewater samples by DI-GC. More importantly, their biases tend to increase systematically with increasing molecular weight and decreasing VFA concentrations. As such, the use of DI-GC method, if applied for the analysis of samples with a complicated matrix, needs a thorough validation to improve the reliability in data acquisition.

  5. A review on development of analytical methods to determine monitorable drugs in serum and urine by micellar liquid chromatography using direct injection. (United States)

    Esteve-Romero, Josep; Albiol-Chiva, Jaume; Peris-Vicente, Juan


    Therapeutic drug monitoring is a common practice in clinical studies. It requires the quantification of drugs in biological fluids. Micellar liquid chromatography (MLC), a well-established branch of Reverse Phase-High Performance Liquid Chromatography (RP-HPLC), has been proven by many researchers as a useful tool for the analysis of these matrices. This review presents several analytical methods, taken from the literature, devoted to the determination of several monitorable drugs in serum and urine by micellar liquid chromatography. The studied groups are: anticonvulsants, antiarrhythmics, tricyclic antidepressants, selective serotonin reuptake inhibitors, analgesics and bronchodilators. We detail the optimization strategy of the sample preparation and the main chromatographic conditions, such as the type of column, mobile phase composition (surfactant, organic solvent and pH), and detection. The finally selected experimental parameters, the validation, and some applications have also been described. In addition, their performances and advantages have been discussed. The main ones were the possibility of direct injection, and the efficient chromatographic elution, in spite of the complexity of the biological fluids. For each substance, the measured concentrations were accurate and precise at their respective therapeutic range. It was found that the MLC-procedures are fast, simple, inexpensive, ecofriendly, safe, selective, enough sensitive and reliable. Therefore, they represent an excellent alternative for the determination of drugs in serum and urine for monitoring purposes.

  6. Design of a direct-injection photoelectric nephelometer%一种直射式光电浊度计的设计

    Institute of Scientific and Technical Information of China (English)

    兰羽; 张顺星


    The turbidity of water is an important index to reflect the quality of water, in order to detect the content of the floating things in the liquid, the system uses the double optical path structure on the basis of the measured liquid referenced and compared with the standard sample liquid, and it designs a direct-injection photoelectric turbidity measurement system, whose hardware circuit includes signal processing module, signal processing microcontroller AT89S51 module, data processing module and liquid crystal display module LCD1602. the system is debugged after standardized with stable measurment results, whose linear error is less than ±1%.%水的浊度是反映水质优劣的一个十分重要的指标,为了检测液体中的浮游物的含量,系统采用了被测液体与标准样本液体参考比对的双光路结构,设计了一种直射式光电浊度测量装置,硬件电路包括信号检测处理模块,信号处理模块,单片机AT89S51数据处理模块及液晶LCD1602显示模块.系统经标定后调试,测量结果稳定,线性误差小于±1%.

  7. An Eco-Friendly Direct Injection HPLC Method for Methyldopa Determination in Serum by Mixed-Mode Chromatography Using a Single Protein-Coated Column. (United States)

    Emara, Samy; Masujima, Tsutomu; Zarad, Walaa; Kamal, Maha; Fouad, Marwa; El-Bagary, Ramzia


    A simple, rapid and environment-friendly direct injection HPLC method for the determination of methyldopa (MTD) in human serum has been developed and validated. The method was based on cleanup and separation of MTD from serum by mixed-mode liquid chromatography using a single protein-coated TSK gel ODS-80 TM analytical column (50 × 4.0 mm i.d., 5 µm). The protein-coated column exhibited excellent resolution, selectivity and functioned in two chromatographic modes: size-exclusion chromatography [i.e., solid-phase extraction (SPE) for serum proteins] and reversed-phase chromatography for the final separation of MTD. SPE and HPLC separation were carried out simultaneously with a green mobile phase consisting of acetate buffer (0.1 M, pH 2.4) at a flow rate of 1 mL/min and at room temperature (23 ± 1°C). The eluent was monitored at emission and excitation wavelengths of 320 and 270 nm, respectively. A calibration curve was linear over the range of 0.1-30 µg/mL with a detection limit of 0.027 µg/mL. This online SPE method was successfully applied to real samples obtained from patients receiving MTD therapy.

  8. Direct injection liquid chromatography/electrospray ionization mass spectrometric horse urine analysis for the quantification and confirmation of threshold substances for doping control. II. Determination of theobromine. (United States)

    Vonaparti, A; Lyris, E; Panderi, I; Koupparis, M; Georgakopoulos, C


    In equine sport, theobromine is prohibited with a threshold level of 2 microg mL(-1) in urine, hence doping control laboratories have to establish quantitative and qualitative methods for its determination. Two simple liquid chromatography/mass spectrometry (LC/MS) methods for the identification and quantification of theobromine were developed and validated using the same sample preparation procedure but different mass spectrometric systems: ion trap mass spectrometry (ITMS) and time-of-flight mass spectrometry (TOFMS). Particle-free diluted urine samples were directly injected into the LC/MS systems, avoiding the time-consuming extraction step. 3-Propylxanthine was used as the internal standard. The tested linear range was 0.75-15 microg mL(-1). Matrix effects were evaluated analyzing calibration curves in water and different fortified horse urine samples. A great variation in the signal of theobromine and the internal standard was observed in different matrices. To overcome matrix effects, a standard additions calibration method was applied. The relative standard deviations of intra- and inter-day analysis were lower than 8.6 and 7.2%, respectively, for the LC/ITMS method and lower than 5.7 and 5.8%, respectively, for the LC/TOFMS method. The bias was less than 8.7% for both methods. The methods were applied to two case samples, demonstrating simplicity, accuracy and selectivity.

  9. Trace analysis of pesticides in paddy field water by direct injection using liquid chromatography-quadrupole-linear ion trap-mass spectrometry. (United States)

    Pareja, Lucía; Martínez-Bueno, M J; Cesio, Verónica; Heinzen, Horacio; Fernández-Alba, A R


    A multiresidue method was developed for the quantification and confirmation of 70 pesticides in paddy field water. After its filtration, water was injected directly in a liquid chromatograph coupled to a hybrid triple quadrupole-linear ion trap-mass spectrometer (QqLIT). The list of target analytes included organophosphates, phenylureas, sulfonylureas, carbamates, conazoles, imidazolinones and others compounds widely used in different countries where rice is cropped. Detection and quantification limits achieved were in the range from 0.4 to 80 ng L(-1) and from 2 to 150 ng L(-1), respectively. Correlation coefficients for the calibration curves in the range 0.1-50 μg L(-1) were higher than 0.99 except for diazinon (0.1-25 μg L(-1)). Only 9 pesticides presented more than 20% of signal suppression/enhancement, no matrix effect was observed in the studied conditions for the rest of the target pesticides. The method developed was used to investigate the occurrence of pesticides in 59 water samples collected in paddy fields located in Spain and Uruguay. The study shows the presence of bensulfuron methyl, tricyclazole, carbendazim, imidacloprid, tebuconazole and quinclorac in a concentration range from 0.08 to 7.20 μg L(-1). Copyright © 2011 Elsevier B.V. All rights reserved.

  10. Hydrocarbon raw emission characterization of a direct-injection spark ignition engine operated with alcohol and furan-based bio fuels

    Energy Technology Data Exchange (ETDEWEB)

    Thewes, Matthias [FEV GmbH, Aachen (Germany); Mauermann, Peter; Pischinger, Stefan [RWTH Aachen Univ. (Germany). Inst. for Combustion Engines; Bluhm, Kerstin; Hollert, Henner [RWTH Aachen Univ. (Germany). Inst. for Environmental Research, Dept. of Ecosystem Analysis


    Within the Cluster of Excellence ''Tailor-Made Fuels from Biomass'' the impact of various potential bio fuels on engine combustion is studied. Besides alcohols, furan-based bio fuels have come into the focus with novel production routes to transform biomass into 2-Methylfuran or 2,5-Dimethylfuran. In the present study, the influence of these and other bio fuels on the hydrocarbon raw emission spectrum of a direct-injection spark-ignition single cylinder engine is studied experimentally by means of gas chromatographic and mass spectroscopic analysis of exhaust gas samples. The results obtained are compared to operation with conventional EN 228 gasoline fuel. This fuel showed slip of partially carcinogenic aromatic fuel molecule(s) in warm and in cold engine conditions. For the bio fuels, slip was found to be significant for the alcohol fuels. The carcinogenic molecule 1,3-Butadiene was present in the exhaust gas of all fuels. Furan as another possibly carcinogenic molecule was found at significantly higher concentrations in the exhaust gas of the furan-based bio fuels compared to conventional gasoline fuel but not in the exhaust gas of the alcohol fuels. (orig.)

  11. Comparison of the effect of biodiesel-diesel and ethanol-diesel on the gaseous emission of a direct-injection diesel engine (United States)

    Di, Yage; Cheung, C. S.; Huang, Zuohua

    Experiments were conducted on a 4-cylinder direct-injection diesel engine using ultralow sulfur diesel blended with biodiesel and ethanol to investigate the gaseous emissions of the engine under five engine loads at the maximum torque engine speed of 1800 rev min -1. Four biodiesel blended fuels and four ethanol blended fuels with oxygen concentrations of 2%, 4%, 6% and 8% were used. With the increase of oxygen content in the blended fuels, the brake thermal efficiency improves slightly. For the diesel-biodiesel fuels, the brake specific HC and CO emissions decrease while the brake specific NO x and NO 2 emissions increase. The emissions of formaldehyde, 1,3-butadiene, toluene, xylene and overall BTX (benzene, toluene, xylene) in general decrease, however, acetaldehyde and benzene emissions increase. For the diesel-ethanol fuels, the brake specific HC and CO emissions increase significantly at low engine load, NO x emission decreases at low engine load but increases at high engine load. The emissions of benzene and BTX vary with engine load and ethanol content. Similar to the biodiesel-diesel fuels, the formaldehyde, 1,3-butadiene, toluene and xylene emissions decrease while the acetaldehyde and NO 2 emissions increase. Despite having the same oxygen contents in the blended fuels, there are significant differences in the gaseous emissions between the biodiesel-diesel blends and the ethanol-diesel blends.

  12. Effect of palm methyl ester-diesel blends performance and emission of a single-cylinder direct-injection diesel engine (United States)

    Said, Mazlan; Aziz, Azhar Abdul; Said, Mohd Farid Muhamad


    The purpose of this study is to investigate engine performance and exhaust emission when using several blends of neat palm oil methyl ester (POME) with conventional diesel (D2) in a small direct injection diesel engine, and to compare the outcomes to that of the D2 fuel. Engine performances, exhaust emissions, and some other important parameters were observed as a function of engine load and speed. In addition, the effect of modifying compression ratio was also carried out in this study. From the engine experimental work, neat and blended fuels behaved comparably to diesel (D2) in terms of fuel consumption, thermal efficiency and rate of heat released. Smoke density showed better results than that emitted by D2, operating under similar conditions due to the presence of inherited oxygen and lower sulphur content in the biofuel and its blends. The emissions of CO, CO2, and HC were also lower using blended mixtures and in its neat form. However, NOx concentrations were found to be slight higher for POME and its blends and this was largely due to higher viscosity of POME and possibly the presence of nitrogen in the palm methyl ester. General observation indicates that biofuel blends can be use without many difficulties in this type of engine but for optimized operation minor modifications to the engine and its auxiliaries are required.

  13. An Assessment of Combustion Dynamics in a Low-Nox, Second-Generation Swirl-Venturi Lean Direct Injection Combustion Concept (United States)

    Tacina, K. M.; Chang, C. T.; Lee, P.; Mongia, H.; Podboy, D. P.; Dam, B.


    Dynamic pressure measurements were taken during flame-tube emissions testing of three second-generation swirl-venturi lean direct injection (SV-LDI) combustor configurations. These measurements show that combustion dynamics were typically small. However, a small number of points showed high combustion dynamics, with peak-to-peak dynamic pressure fluctuations above 0.5 psi. High combustion dynamics occurred at low inlet temperatures in all three SV-LDI configurations, so combustion dynamics were explored further at low temperature conditions. A point with greater than 1.5 psi peak-to-peak dynamic pressure fluctuations was identified at an inlet temperature of 450!F, a pressure of 100 psia, an air pressure drop of 3%, and an overall equivalence ratio of 0.35. This is an off design condition: the temperature and pressure are typical of 7% power conditions, but the equivalence ratio is high. At this condition, the combustion dynamics depended strongly on the fuel staging. Combustion dynamics could be reduced significantly without changing the overall equivalence ratio by shifting the fuel distribution between stages. Shifting the fuel distribution also decreased NOx emissions.

  14. The comparison of engine performance and exhaust emission characteristics of sesame oil-diesel fuel mixture with diesel fuel in a direct injection diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Altun, Sehmus [Technical Education Faculty, Automotive Division, Batman University, Batman (Turkey); Bulut, Huesamettin [Department of Mechanical Engineering, Osmanbey Campus, Harran University, 63100 Sanliurfa (Turkey); Oener, Cengiz [Technical Education Faculty, Automotive Division, Firat University, Elazig (Turkey)


    The use of vegetable oils as a fuel in diesel engines causes some problems due to their high viscosity compared with conventional diesel fuel. Various techniques and methods are used to solve the problems resulting from high viscosity. One of these techniques is fuel blending. In this study, a blend of 50% sesame oil and 50% diesel fuel was used as an alternative fuel in a direct injection diesel engine. Engine performance and exhaust emissions were investigated and compared with the ordinary diesel fuel in a diesel engine. The experimental results show that the engine power and torque of the mixture of sesame oil-diesel fuel are close to the values obtained from diesel fuel and the amounts of exhaust emissions are lower than those of diesel fuel. Hence, it is seen that blend of sesame oil and diesel fuel can be used as an alternative fuel successfully in a diesel engine without any modification and also it is an environmental friendly fuel in terms of emission parameters. (author)

  15. Burning mouth syndrome

    Directory of Open Access Journals (Sweden)

    K A Kamala


    Full Text Available Burning mouth syndrome (BMS is multifactorial in origin which is typically characterized by burning and painful sensation in an oral cavity demonstrating clinically normal mucosa. Although the cause of BMS is not known, a complex association of biological and psychological factors has been identified, suggesting the existence of a multifactorial etiology. As the symptom of oral burning is seen in various pathological conditions, it is essential for a clinician to be aware of how to differentiate between symptom of oral burning and BMS. An interdisciplinary and systematic approach is required for better patient management. The purpose of this study was to provide the practitioner with an understanding of the local, systemic, and psychosocial factors which may be responsible for oral burning associated with BMS, and review of treatment modalities, therefore providing a foundation for diagnosis and treatment of BMS.

  16. Hand chemical burns. (United States)

    Robinson, Elliot P; Chhabra, A Bobby


    There is a vast and ever-expanding variety of potentially harmful chemicals in the military, industrial, and domestic landscape. Chemical burns make up a small proportion of all skin burns, yet they can cause substantial morbidity and mortality. Additionally, the hand and upper extremity are the most frequently involved parts of the body in chemical burns, and therefore these injuries may lead to severe temporary or permanent loss of function. Despite this fact, discussion of the care of these injuries is sparse in the hand surgery literature. Although most chemical burns require only first response and wound care, some require the attention of a specialist for surgical debridement and, occasionally, skin coverage and reconstruction. Exposure to certain chemicals carries the risk of substantial systemic toxicity and even mortality. Understanding the difference between thermal and chemical burns, as well as special considerations for specific compounds, will improve patient treatment outcomes.

  17. [Chickenpox, burns and grafts]. (United States)

    Rojas Zegers, J; Fidel Avendaño, L


    An outbreak of chickenpox that occurred at the Burns Repair Surgery Unit, Department of Children's Surgery, Hospital R. del Río, between June and November, 1975, is reported. 27 cases of burned children were studied, including analysis of correlations of the stages and outcome of the disease (varicela), the trauma (burns) and the graft (repair surgery). As a result, the authors emphasize the following findings: 1. Burns and their repair are not aggravating factors for varicella. In a small number of cases the exanthema looked more confluent in the graft surgical areas and in the first degree burns healing spontaneously. 2. Usually there was an uneventful outcome of graft repair surgery on a varicella patient, either during the incubation period, the acme or the convalescence. 3. The fact that the outmost intensity of secondary viremia of varicella occurs before the onset of exanthemia, that is, during the late incubation period, is confirmed.

  18. Crude oil burning mechanisms

    DEFF Research Database (Denmark)

    van Gelderen, Laurens; Malmquist, Linus Mattias Valdemar; Jomaas, Grunde


    In order to improve predictions for the burning efficiency and the residue composition of in-situ burning of crude oil, the burning mechanism of crude oil was studied in relation to the composition of its hydrocarbon mixture, before, during and after the burning. The surface temperature, flame...... height, mass loss rate and residues of three hydrocarbon liquids (n-octane, dodecane and hexadecane), two crude oils (DUC and REBCO) and one hydrocarbon liquid mixture of the aforementioned hydrocarbon liquids were studied using the Crude Oil Flammability Apparatus. The experimental results were compared...... to the predictions of four conceptual models that describe the burning mechanism of multicomponent fuels. Based on the comparisons, hydrocarbon liquids were found to be best described by the Equilibrium Flash Vaporization model, showing a constant gas composition and gasification rate. The multicomponent fuels...

  19. PS injection area

    CERN Multimedia


    To the right is the PS ring viewed along the direction of the protons. At the left the injection line coming from the 50 MeV Linac 1 (bottom) and going towards the 800 MeV booster, or deflected to the right to be injected directly into straight section 16. The drumlike element behind the (blue) dipole magnet is a 'debuncher' (a 200 MHz cavity). See photos 7409014X and 7409009.

  20. Doripenem Injection (United States)

    ... injection is in a class of medications called carbapenem antibiotics. It works by killing bacteria.Antibiotics such ... if you are allergic to doripenem injection; other carbapenem antibiotics such as imipenem/cilastatin (Primaxin) or meropenem ( ...

  1. Methotrexate Injection (United States)

    Methotrexate injection is used alone or in combination with other medications to treat gestational trophoblastic tumors (a ... in bones) after surgery to remove the tumor. Methotrexate injection is also used to treat severe psoriasis ( ...

  2. Bendamustine Injection (United States)

    Bendamustine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white ... injection. You should use birth control to prevent pregnancy in yourself or your partner during your treatment ...

  3. Caspofungin Injection (United States)

    Caspofungin injection is used in adults and children 3 months of age and older to treat yeast ... people with a weakened ability to fight infection. Caspofungin injection is in a class of antifungal medications ...

  4. Temozolomide Injection (United States)

    Temozolomide is used to treat certain types of brain tumors. Temozolomide is in a class of medications called alkylating ... Temozolomide injection comes as a powder to be added to fluid and injected over 90 minutes intravenously ( ...

  5. Pembrolizumab Injection (United States)

    Pembrolizumab injection is used to treat melanoma (a type of skin cancer) that cannot be treated with ... who have a specific type of melanoma tumor. Pembrolizumab injection is also used to treat a certain ...

  6. Lacosamide Injection (United States)

    ... injection is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in ... older (about 1 in 500 people) who took anticonvulsants like lacosamide injection to treat various conditions during ...

  7. Midazolam Injection (United States)

    ... injection is in a class of medications called benzodiazepines. It works by slowing activity in the brain ... to your doctor about the risks and benefits of receiving midazolam injection if you ...

  8. Doxycycline Injection (United States)

    Doxycycline injection is used to treat or prevent bacterial infections, including pneumonia and other respiratory tract infections. ... certain skin, genital, intestine, and urinary system infections. Doxycycline injection may be used to treat or prevent ...

  9. Paclitaxel Injection (United States)

    ... with other medications. Paclitaxel injection manufactured with polyoxyethylated castor oil is used to treat ovarian cancer (cancer that ... cancer, and lung cancer. Paclitaxel injection with polyoxyethylated castor oil is also used to treat Kaposi's sarcoma (a ...

  10. Etanercept Injection (United States)

    ... will be using the prefilled syringe or automatic injection device, tell your doctor if you or the person who will be injecting the medication for you are allergic to rubber or latex.tell your doctor and pharmacist what ...

  11. Cyclosporine Injection (United States)

    Cyclosporine injection is used with other medications to prevent transplant rejection (attack of the transplanted organ by ... who have received kidney, liver, and heart transplants. Cyclosporine injection should only be used to treat people ...

  12. Estrogen Injection (United States)

    The estradiol cypionate and estradiol valerate forms of estrogen injection are used to treat hot flushes (hot ... should consider a different treatment. These forms of estrogen injection are also sometimes used to treat the ...

  13. Cefotaxime Injection (United States)

    Cefotaxime injection is used to treat certain infections caused by bacteria including pneumonia and other lower respiratory ... skin, blood, bone, joint, and urinary tract infections. Cefotaxime injection may also be used before surgery, and ...

  14. New type of sauna-related burn: conductive contact burn. (United States)

    Shin, Seung Jun; Yoo, Heon; Park, Myong Chul


    A 70-year-old woman visited a Korean-style hot dry sauna room. The patient had a medical history of hypertension and hyperlipidemia. During the sauna, the patient slept for 30 minutes. During the sleep, the right medial thigh was covered with a fully wet towel. The patient sustained a second-degree burn on the right medial thigh area with multiple bullas. On physical examination, erythema, heating sensation, and swelling around the bullas were noted. The patient was admitted and received intravenous antibiotics for 7 days. A dressing with Silmazine 1% cream (sulfadiazine) was applied twice a day for prevention of local infection. The patient was discharged on day 14 without complication. In this case, the mechanism of the burn was different. Hot air has much thermal energy but is not conducted to the skin directly. A wet towel will have a relatively higher thermal capacity or heat capacity than a dry or damp towel, and the sodden water might be a medium for the conduction of thermal energy. Owing to the global popularity of sauna bathing, it is important to recognize all sources of sauna-related burns.

  15. Current concepts on burn wound conversion-A review of recent advances in understanding the secondary progressions of burns. (United States)

    Salibian, Ara A; Rosario, Angelica Tan Del; Severo, Lucio De Almeida Moura; Nguyen, Long; Banyard, Derek A; Toranto, Jason D; Evans, Gregory R D; Widgerow, Alan D


    Burn wound conversion describes the process by which superficial partial thickness burns convert into deeper burns necessitating surgical intervention. Fully understanding and thus controlling this phenomenon continues to defy burn surgeons. However, potentially guiding burn wound progression so as to obviate the need for surgery while still bringing about healing with limited scarring is the major unmet challenge. Comprehending the pathophysiologic background contributing to deeper progression of these burns is an essential prerequisite to planning any intervention. In this study, a review of articles examining burn wound progression over the last five years was conducted to analyze trends in recent burn progression research, determine changes in understanding of the pathogenesis of burn conversion, and subsequently examine the direction for future research in developing therapies. The majority of recent research focuses on applying therapies from other disease processes to common underlying pathogenic mechanisms in burn conversion. While ischemia, inflammation, and free oxygen radicals continue to demonstrate a critical role in secondary necrosis, novel mechanisms such as autophagy have also been shown to contribute affect significantly burn progression significantly. Further research will have to determine whether multiple mechanisms should be targeted when developing clinical therapies.

  16. Ustekinumab Injection (United States)

    ... Do not inject into an area where the skin is tender, bruised, red, or hard or where you have scars or stretch marks.Your doctor or pharmacist will ... should know that ustekinumab injection may decrease your ability ... new or changing skin lesions, minor infections (such as open cuts or ...

  17. Ranitidine Injection (United States)

    Ranitidine injection comes as a solution (liquid) to be mixed with another fluid and injected intravenously (into a vein) over 5 to 20 minutes. Ranitidine may also be injected into a muscle. It is usually given every 6 to 8 hours, but may also be given ...

  18. Study on a small diesel engine with direct injection impinging distribution spray combustion system. Optimum of injection system and combustion chamber; Shototsu kakusan hoshiki kogata diesel kikan ni kansuru kenkyu. Funshakei to nenshoshitsu no saitekika

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, K.; Kato, S.; Saito, T. [Kanazawa Institute of Technology, Ishikawa (Japan); Tanabe, H. [Gunma University, Gunma (Japan)


    This study is concerned with a small bore (93mm) diesel engine using impinged fuel spray, named OSKA system. The higher rate of injection show lower smoke emission with higher NOx Emission. The exhaust emission and performance were investigated under different compression ratio with higher rate of injection. The experimental results show that this OSKA system is capable for reducing the smoke emission without the deterioration of NOx emission and fuel consumption compared with the conventional DI diesel engine. 5 refs., 8 figs., 3 tabs.

  19. Study of the droplet size of sprays generated by swirl nozzles dedicated to gasoline direct injection: measurement and application of the maximum entropy formalism; Etude de la granulometrie des sprays produits par des injecteurs a swirl destines a l'injection directe essence: mesures et application du formalisme d'entropie maximum

    Energy Technology Data Exchange (ETDEWEB)

    Boyaval, S.


    This PhD presents a study on a series of high pressure swirl atomizers dedicated to Gasoline Direct Injection (GDI). Measurements are performed in stationary and pulsed working conditions. A great aspect of this thesis is the development of an original experimental set-up to correct multiple light scattering that biases the drop size distributions measurements obtained with a laser diffraction technique (Malvern 2600D). This technique allows to perform a study of drop size characteristics near the injector tip. Correction factors on drop size characteristics and on the diffracted intensities are defined from the developed procedure. Another point consists in applying the Maximum Entropy Formalism (MEF) to calculate drop size distributions. Comparisons between experimental distributions corrected with the correction factors and the calculated distributions show good agreement. This work points out that the mean diameter D{sub 43}, which is also the mean of the volume drop size distribution, and the relative volume span factor {delta}{sub v} are important characteristics of volume drop size distributions. The end of the thesis proposes to determine local drop size characteristics from a new development of deconvolution technique for line-of-sight scattering measurements. The first results show reliable behaviours of radial evolution of local characteristics. In GDI application, we notice that the critical point is the opening stage of the injection. This study shows clearly the effects of injection pressure and nozzle internal geometry on the working characteristics of these injectors, in particular, the influence of the pre-spray. This work points out important behaviours that the improvement of GDI principle ought to consider. (author)

  20. Evaluation and development of direct burning natural gas industrial equipment in the food sector; Avaliacao e desenvolvimento de equipamentos industriais de queima direta de gas natural no setor de alimentos

    Energy Technology Data Exchange (ETDEWEB)

    Schwob, Marcelo; Morales, Maria Elizabeth; Henriques, Mauricio; Guimaraes, Marcio; Tapia, Roberto; Rodrigues, Joaquim; Faccion, Alexandre [Instituto Nacional de Tecnologia (INT), Rio de Janeiro, RJ (Brazil)


    The aim of this study, focused in the food sector, is evaluate and develop technologies used in equipment of direct burning natural gas, as ovens and driers of common use in the toasting coffee, noodles and biscuits industries. We have developed an archetype of oven for baking, seeking to incorporate new technological concepts but showing operational conditions of great attractiveness for the users of this kind of equipment. Above all, aiming the optimization of the technologies to improve the energy efficiency, to reduce costs and to increase the operational security. Thus, a survey of the thermal equipment in the mentioned industrial sector was made, followed of an evaluation of the technical possibilities of its incorporation in that sector, adaptations and the modifications of engineering projects, identifying the possibilities of productivity increase, improvement of quality and greater competitiveness, as well as the reduction of atmospheric emissions. So, It has been proposed solutions as the decentralized use of the thermal energy, recovery of heat of exhaustion gases, optimization of the thermal insulation, reduction of thermal inertia and the automatization of the control of the combustion in ovens and/or driers of the mentioned sectors. The main results of this study are: the possibility of reduction of, 32 to 37% in the consumption of thermal energy in the ovens of biscuit production, of 12 to 15% in the toasting of coffee and 20 to 30% in the processes of noodles production. Saving of around 25% would be expected in the small bearing ovens for baking. (author)

  1. Biomass Burning Observation Project Science Plan

    Energy Technology Data Exchange (ETDEWEB)

    Kleinman, KI [Brookhaven National Laboratory; Sedlacek, AJ [Brookhaven National Laboratory


    Aerosols from biomass burning perturb Earth’s climate through the direct radiative effect (both scattering and absorption) and through influences on cloud formation and precipitation and the semi-direct effect. Despite much effort, quantities important to determining radiative forcing such as the mass absorption coefficients (MAC) of light-absorbing carbon, secondary organic aerosol (SOA) formation rates, and cloud condensation nuclei (CCN) activity remain in doubt. Field campaigns in northern temperate latitudes have been overwhelmingly devoted to other aerosol sources in spite of biomass burning producing about one-third of the fine particles (PM2.5) in the U.S.

  2. Sample introduction systems for reversed phase LC-ICP-MS of selenium using large amounts of methanol - comparison of systems based on membrane desolvation, a spray chamber and direct injection

    DEFF Research Database (Denmark)

    Bendahl, L.; Gammelgaard, Bente


    nebuliser (MCN) in combination with a membrane desolvator ( MD), a MCN in combination with a cyclonic spray chamber ( CS) and a direct injection nebuliser ( DIN), respectively. Thirteen selenium standards diluted in 50% methanol were introduced in each system at a flow rate of 50 mu l min(-1). Except...

  3. Prescribed burning plan : Stillwater NWR : de Braga Burn Unit 67 (United States)

    US Fish and Wildlife Service, Department of the Interior — This 1991 Annual Prescribed Burning Plan for Stillwater NWR calls for all 67 acres of the de Braga burn unit to be burned. The objective of this burn is to remove...

  4. Nanoparticle Filtration Characteristics of Advanced Metal Foam Media for a Spark Ignition Direct Injection Engine in Steady Engine Operating Conditions and Vehicle Test Modes

    Directory of Open Access Journals (Sweden)

    Cha-Lee Myung


    Full Text Available In this study, the particle formation and reduction characteristics at the engine-out position, after a three-way catalyst (TWC and a metal foam gasoline particulate filter (GPF, were evaluated for a gasoline direct-injection (GDI engine under part-load operating conditions. The vehicle tests were performed under the Federal Test Procedure-75 (FTP-75 and the Highway Fuel Economy Test (HWFET modes. Particle number (PN concentrations, size distributions, and the filtering efficiency with the GPF were evaluated with a condensation particle counter (CPC and a differential mobility spectrometer (DMS500. Under steady engine operating conditions, the PN concentrations at the engine-out position were 9.7 × 105–2.5 × 106 N/cc. While, the PN concentrations after the GPF were 9.2 × 104–3.5 × 105 N/cc, and the PN was reduced by 77%–96%. The PN filtering efficiency with the GPF-GDI vehicle reached approximately 58% in the FTP-75 and 62% in the HWFET mode. The PN concentration of the GPF-GDI vehicle was significantly reduced to 3.95 × 1011 N/km for the FTP-75 and 8.86 × 1010 N/km for the HWFET mode. The amount of nucleation mode particles below 23 nm was substantially reduced with the GPF-GDI vehicle. The fuel economy, CO2, and regulated emissions of the GPF-GDI vehicle were equivalent to those of the base GDI vehicle under the vehicle certification modes.

  5. Knock Resistance and Fine Particle Emissions for Several Biomass-Derived Oxygenates in a Direct-Injection Spark-Ignition Engine

    Energy Technology Data Exchange (ETDEWEB)

    Ratcliff, Matthew A.; Burton, Jonathan; Sindler, Petr; Christensen, Earl; Fouts, Lisa; Chupka, Gina M.; McCormick, Robert L.


    Several high octane number oxygenates that could be derived from biomass were blended with gasoline and examined for performance properties and their impact on knock resistance and fine particle emissions in a single cylinder direct-injection spark-ignition engine. The oxygenates included ethanol, isobutanol, anisole, 4-methylanisole, 2-phenylethanol, 2,5-dimethyl furan, and 2,4-xylenol. These were blended into a summertime blendstock for oxygenate blending at levels ranging from 10 to 50 percent by volume. The base gasoline, its blends with p-xylene and p-cymene, and high-octane racing gasoline were tested as controls. Relevant gasoline properties including research octane number (RON), motor octane number, distillation curve, and vapor pressure were measured. Detailed hydrocarbon analysis was used to estimate heat of vaporization and particulate matter index (PMI). Experiments were conducted to measure knock-limited spark advance and particulate matter (PM) emissions. The results show a range of knock resistances that correlate well with RON. Molecules with relatively low boiling point and high vapor pressure had little effect on PM emissions. In contrast, the aromatic oxygenates caused significant increases in PM emissions (factors of 2 to 5) relative to the base gasoline. Thus, any effect of their oxygen atom on increasing local air-fuel ratio was outweighed by their low vapor pressure and high double-bond equivalent values. For most fuels and oxygenate blend components, PMI was a good predictor of PM emissions. However, the high boiling point, low vapor pressure oxygenates 2-phenylethanol and 2,4-xylenol produced lower PM emissions than predicted by PMI. This was likely because they did not fully evaporate and combust, and instead were swept into the lube oil.

  6. Unenhanced Cone Beam Computed Tomography and Fusion Imaging in Direct Percutaneous Sac Injection for Treatment of Type II Endoleak: Technical Note

    Energy Technology Data Exchange (ETDEWEB)

    Carrafiello, Gianpaolo, E-mail:; Ierardi, Anna Maria [Insubria University, Interventional Radiology, Department of Radiology (Italy); Radaelli, Alessandro [Philips Healthcare (Netherlands); Marchi, Giuseppe De; Floridi, Chiara [Insubria University, Interventional Radiology, Department of Radiology (Italy); Piffaretti, Gabriele [University of Insubria, Vascular Surgery Department (Italy); Federico, Fontana [Insubria University, Interventional Radiology, Department of Radiology (Italy)


    AimTo evaluate safety, feasibility, technical success, and clinical success of direct percutaneous sac injection (DPSI) for the treatment of type II endoleaks (T2EL) using anatomical landmarks on cone beam computed tomography (CBCT) and fusion imaging (FI).Materials and MethodsEight patients with T2EL were treated with DPSI using CBCT as imaging guidance. Anatomical landmarks on unenhanced CBCT were used for referencing T2EL location in the first five patients, while FI between unenhanced CBCT and pre-procedural computed tomography angiography (CTA) was used in the remaining three patients. Embolization was performed with thrombin, glue, and ethylene–vinyl alcohol copolymer. Technical and clinical success, iodinated contrast utilization, procedural time, fluoroscopy time, and mean radiation dose were registered.ResultsDPSI was technically successful in all patients: the needle was correctly positioned at the first attempt in six patients, while in two of the first five patients the needle was repositioned once. Neither minor nor major complications were registered. Average procedural time was 45 min and the average administered iodinated contrast was 13 ml. Mean radiation dose of the procedure was 60.43 Gy cm{sup 2} and mean fluoroscopy time was 18 min. Clinical success was achieved in all patients (mean follow-up of 36 months): no sign of T2EL was reported in seven patients until last CT follow-up, while it persisted in one patient with stability of sac diameter.ConclusionsDPSI using unenhanced CBCT and FI is feasible and provides the interventional radiologist with an accurate and safe alternative to endovascular treatment with limited iodinated contrast utilization.

  7. PBXN-110 Burn Rate Estimate

    Energy Technology Data Exchange (ETDEWEB)

    Glascoe, E


    It is estimated that PBXN-110 will burn laminarly with a burn function of B = (0.6-1.3)*P{sup 1.0} (B is the burn rate in mm/s and P is pressure in MPa). This paper provides a brief discussion of how this burn behavior was estimated.

  8. Management of burn wounds. (United States)

    Schiestl, Clemens; Meuli, Martin; Trop, Marija; Neuhaus, Kathrin


    Small and moderate scalds in toddlers are still the most frequent thermal injuries the pediatric surgeons have to face today. Over the last years, surgical treatment of these patients has changed in many aspects. Due to new dressing materials and new surgical treatment strategies that are particularly suitable for children, today, far better functional and aesthetic long-term results are possible. While small and moderate thermal injuries can be treated in most European pediatric surgical departments, the severely burned child must be transferred to a specialized, ideally pediatric, burn center, where a well-trained multidisciplinary team under the leadership of a (ideally pediatric) burn surgeon cares for these highly demanding patients. In future, tissue engineered full thickness skin analogues will most likely play an important role, in pediatric burn as well as postburn reconstructive surgery.

  9. Burn Wise Awareness Kit (United States)

    Health and safety outreach materials in the form of an awareness kit. Designed specifically for state, local, and tribal air agencies working to reduce wood smoke pollution, it includes best burn tips, social media m

  10. Molten Metal Burns


    Kahn, Arthur M.; McCrady-Kahn, Virginia L.


    Molten metal burns are a frequent industrial injury among workers in foundries. The injury is typically small but very deep. Usually the depth and seriousness of these injuries is not recognized immediately by emergency department or industrial clinic physicians.

  11. New Fashioned Book Burning. (United States)

    Gardner, Robert


    Reports on results of a teacher's experiment in book burning as a lesson accompanying the teaching of Ray Bradbury's "Fahrenheit 451." Discusses student reactions and the purpose of or justification for the experimental lesson. (TB)

  12. Accidental burns during surgery. (United States)

    Demir, Erhan; O'Dey, Dan Mon; Pallua, Norbert


    The purpose of this report is to increase awareness of intraoperative burns during standard procedures, to discuss their possible causes and warning signs and to provide recommendations for prevention and procedures to follow after their occurrence. A total of 19 patients associated with intraoperative burn accidents were treated surgically and analyzed after a mean follow-up of 5 +/- 3.5 months. Review included retrospective patient chart analysis, clinical examination, and technical device and equipment testing. A total of 15 patients recently underwent cardiac surgery, and 4 pediatric patients recovered after standard surgical procedures. A total of 15 patients had superficial and 4 presented with deep dermal or full-thickness burns. The average injured TBSA was 2.1 +/- 1% (range, 0.5-4%). Delay between primary surgery and consultation of plastic surgeons was 4.5 +/- 3.4 days. A total of 44% required surgery, including débridment, skin grafting or musculocutaneous gluteus maximus flaps, and the remaining patients were treated conservatively. Successful durable soft-tissue coverage of the burn region was achieved in 18 patients, and 1 patient died after a course of pneumonia. Technical analysis demonstrated one malfunctioning electrosurgical device, one incorrect positioned neutral electrode, three incidents occurred after moisture under the negative electrode, eight burns occurred during surgery while fluid or blood created alternate current pathways, five accidents were chemical burns after skin preparation with Betadine solution, and in one case, the cause was not clear. The surgical team should pay more attention to the probability of burns during surgery. Early patient examination and immediate involvement of plastic and burn surgeons may prevent further complications or ease handling after the occurrence.

  13. Smartphone applications in burns. (United States)

    Wurzer, Paul; Parvizi, Daryousch; Lumenta, David B; Giretzlehner, Michael; Branski, Ludwik K; Finnerty, Celeste C; Herndon, David N; Tuca, Alexandru; Rappl, Thomas; Smolle, Christian; Kamolz, Lars P


    Since the introduction of applications (apps) for smartphones, the popularity of medical apps has been rising. The aim of this review was to demonstrate the current availability of apps related to burns on Google's Android and Apple's iOS store as well as to include a review of their developers, features, and costs. A systematic online review of Google Play Store and Apple's App Store was performed by using the following search terms: "burn," "burns," "thermal," and the German word "Verbrennung." All apps that were programmed for use as medical apps for burns were included. The review was performed from 25 February until 1 March 2014. A closer look at the free and paid calculation apps including a standardized patient was performed. Four types of apps were identified: calculators, information apps, book/journal apps, and games. In Google Play Store, 31 apps were related to burns, of which 20 were calculation apps (eight for estimating the total body surface area (TBSA) and nine for total fluid requirement (TFR)). In Apple's App Store, under the category of medicine, 39 apps were related to burns, of which 21 were calculation apps (19 for estimating the TBSA and 17 for calculating the TFR). In 19 out of 32 available calculation apps, our study showed a correlation of the calculated TFR compared to our standardized patient. The review demonstrated that many apps for medical burns are available in both common app stores. Even free available calculation apps may provide a more objective and reproducible procedure compared to manual/subjective estimations, although there is still a lack of data security especially in personal data entered in calculation apps. Further clinical studies including smartphone apps for burns should be performed. Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.

  14. Fundamental Study of Direct Injection Diesel Engine Fuelled with Hydrogen(1st Report: Analysis on Process of Mixture Formation in Unsteady Hydrogen Jet)


    藤本, 元; 千田, 二郎; 大田, 篤志; フジモト, ハジメ; センダ, ジロウ; オオタ, アツシ; Fujimoto, Hajime; Senda, Jiro; Ohta, Atsushi


    In this study, the mixture formation processes of high pressure hydrogen jets were investigated using a constant-volume vessel. The mixture formations of steady gas jets injected into atmospheric pressure ambient are well known. However, there are few works about the mixture formations of high pressure hydrogen jets injected into high pressure ambient. Also, in gas releases having a pressure ratio of exit pressure to ambient pressure greater than 1.89, underexpanded jet will be formed. So the...

  15. Burn mouse models

    DEFF Research Database (Denmark)

    Calum, Henrik; Høiby, Niels; Moser, Claus


    Severe thermal injury induces immunosuppression, involving all parts of the immune system, especially when large fractions of the total body surface area are affected. An animal model was established to characterize the burn-induced immunosuppression. In our novel mouse model a 6 % third-degree b......Severe thermal injury induces immunosuppression, involving all parts of the immune system, especially when large fractions of the total body surface area are affected. An animal model was established to characterize the burn-induced immunosuppression. In our novel mouse model a 6 % third......-degree burn injury was induced with a hot-air blower. The third-degree burn was confirmed histologically. At 48 h, a decline in the concentration of peripheral blood leucocytes was observed in the group of mice with burn wound. The reduction was ascribed to the decline in concentration of polymorphonuclear...... neutrophil leucocytes and monocytes. When infecting the skin with Pseudomonas aeruginosa, a dissemination of bacteria was observed only in the burn wound group. Histological characterization of the skin showed an increased polymorphonuclear neutrophil granulocytes dominated inflammation in the group of mice...

  16. Feet sunk in molten aluminium: The burn and its prevention. (United States)

    Alonso-Peña, David; Arnáiz-García, María Elena; Valero-Gasalla, Javier Luis; Arnáiz-García, Ana María; Campillo-Campaña, Ramón; Alonso-Peña, Javier; González-Santos, Jose María; Fernández-Díaz, Alaska Leonor; Arnáiz, Javier


    Nowadays, despite improvements in safety rules and inspections in the metal industry, foundry workers are not free from burn accidents. Injuries caused by molten metals include burns secondary to molten iron, aluminium, zinc, copper, brass, bronze, manganese, lead and steel. Molten aluminium is one of the most common causative agents of burns (60%); however, only a few publications exist concerning injuries from molten aluminium. The main mechanisms of lesion from molten aluminium include direct contact of the molten metal with the skin or through safety apparel, or when the metal splash burns through the pants and rolls downward along the leg. Herein, we report three cases of deep dermal burns after 'soaking' the foot in liquid aluminium and its evolutive features. This paper aims to show our experience in the management of burns due to molten aluminium. We describe the current management principles and the key features of injury prevention. Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.

  17. Burns Caused by Medical Therapy (United States)


    fear of litigation, patients with such injuries, even if the injuries are minor, arc often referred to a burn center for care. Burn injury...the potential burn hazards found elsewhere in the hospital. Even fewer studies have addressed the burn risks posed by medical therapy administered...35. Mills GH, Ralph S). Bums due to pulse oximetry [ letter ]. Anaesthesia 1992j47:276·7. 36. Shdlock: FG, Kana! E. Burns associated with the use of

  18. Direct injection, simple and robust analysis of trace-level bromate and bromide in drinking water by IC with suppressed conductivity detection. (United States)

    Lawal, Wasiu; Gandhi, Jay; Zhang, Chunlong Carl


    Bromide is ubiquitously found in drinking water. It is introduced into source water primarily by contact with bromide-containing soils or seawater having high bromide content. Bromide is converted into carcinogenic bromate during ozonation processes employed in some drinking water and wastewater treatment plants. Therefore, monitoring of bromate in drinking water and its precursor bromide in source water is required. The purpose of this study was to survey bromide and bromate concentrations in randomly selected bottle waters of various brands and several tap water samples in the coastal Houston area using a direct-injection ion chromatography (IC) and a suppressed conductivity system. The method employs a simple isocratic IC with loop injection with calculated detection limit of 0.009 microg/L for bromate and 0.028 microg/L for bromide (250-microL sample volume). Allowing the detection of both species at the microg/L level in drinking water, this method does not require specialized instrumentation such as two-dimensional IC, expensive sample preparation, or post-column reactions. The results show that, whereas bromate remains undetected in all five tap water samples, there are significant high concentrations of bromide in the coastal Houston area (294.79 +/- 56.97 microg/L). Its link to potential seawater intrusion need to be further investigated. For bottle water samples randomly collected, 18.2% (2 out of 11) showed detectable amount of both bromide and bromate. The detection of bromate coincides with those bottle water samples that underwent ozonation treatment. Further sample campaign with exclusively ozonated bottle water samples (n = 19) showed 100% detection rate for both bromide and bromate. The 99% confidence intervals were 14.45-37.97 microg/L and 0.32-2.58 microg/L for bromide and bromate, respectively. The highest level of bromate among all ozonated bottle water samples was 7.57 microg/L, a concentration close to the U.S. EPA prescribed limit for

  19. Burn-injured adolescents report gaining multiple developmental benefits and improved life skills as a result of burn camp attendance. (United States)

    Rimmer, Ruth Brubaker; Pressman, Melissa S; Takach, Oliver P; Bay, R Curtis; Croteau, Renee; Hansen, Linda D; Foster, Kevin N; Caruso, Daniel M


    Anecdotally, burn camp has been reported to be a positive developmental and rehabilitative experience for attendees; there is little empirical data to support this belief. This study sought to explore whether burn camp either directly or indirectly elicits positive development outcomes in pediatric burn survivors or increases their psychosocial well-being and achievement. The Youth Experience Survey 2.0, a 66-item self-report inventory designed to measure developmental experiences in an organized youth activity, was administered to children aged 11 to 18 years attending summer burn camp. One hundred and ten burn-injured youth, 58 male and 52 female, reported that burn camp had positively impacted their lives through improved identity exploration, goal-setting and problem-solving abilities, increased physical activity, communication, emotional regulation, and time management skills (P camp for more than 5 years resulted in greater improvement. Study results support the burn camp experience as a far-reaching and positive developmental activity. Participants credited the camp experience with helping them with identity formation and reflection, improved social interactions, and increased initiative; all positive developmental outcomes for youth. Results suggest that burn camp participation not only helps burn-injured youth to deal with their burns but also assists them in the development of social and basic life skills, which will allow them to navigate the transition from youth to adulthood, more effectively and successfully.

  20. Burn patients' experience of pain management: a qualitative study. (United States)

    Yuxiang, Li; Lingjun, Zhou; Lu, Tang; Mengjie, Liu; Xing, Ming; Fengping, Shen; Jing, Cui; Xianli, Meng; Jijun, Zhao


    Pain is a major problem after burns and researchers continue to report that pain from burns remains undertreated. The inadequate pain control results in adverse sequalae physically and psychologically in the burn victims. A better understanding of a burn patient's experience is important in identifying the factors responsible for undertreated pain and establishing effective pain management guidelines or recommendation in the practice of pain relief for burn injuries. This study sought to explore and describe the experience that patients have about pain related to burn-injury during hospitalization. Semi-structured interviews were conducted on eight patients with moderate to severe pain from burn injuries recruited from a Burn Centre in Northwest China. Data was collected by in-depth interviews and qualitative description after full transcription of each interview. Analysis involved the identification of themes and the development of a taxonomy of patients' experience of burn pain and its management. Three themes were indentified: (1) patients' experience of pain control, (2) patients' perception on burn pain management, and (3) patients' expectation of burn pain management. Findings from this study suggested that patients experience uncontrolled pain both physically and psychologically which may serve as an alert for awareness of health professionals to recognize and establish a multidisciplinary pain management team for burn victims, including surgeons, critical care specialists, anesthesiologists, nurses, psychologists, and social workers to accomplish safe and effective strategies for pain control to reach an optimal level of pain management in burn patients. It also provides insights and suggestions for future research directions to address this significant clinical problem.

  1. Subcutaneous Injections

    DEFF Research Database (Denmark)

    Thomsen, Maria

    This thesis is about visualization and characterization of the tissue-device interaction during subcutaneous injection. The tissue pressure build-up during subcutaneous injections was measured in humans. The insulin pen FlexTouchr (Novo Nordisk A/S) was used for the measurements and the pressure...... build-up was evaluated indirectly from the changes in the flow rate between subcutaneous injections and air injections. This method enabled the tissue counter pressure to be evaluated without a formal clinical study approval. The measurements were coupled to a model for the pressure evolution...

  2. The Physiologic Basis of Burn Shock and the Need for Aggressive Fluid Resuscitation. (United States)

    Rae, Lisa; Fidler, Philip; Gibran, Nicole


    Burn trauma in the current age of medical care still portends a 3% to 8% mortality. Of patients who die from their burn injuries, 58% of deaths occur in the first 72 hours after injury, indicating death from the initial burn shock is still a major cause of burn mortality. Significant thermal injury incites an inflammatory response, which distinguishes burns from other trauma. This article focuses on the current understanding of the pathophysiology of burn shock, the inflammatory response, and the direction of research and targeted therapies to improve resuscitation, morbidity, and mortality.

  3. Determination of human-use pharmaceuticals in filtered water by direct aqueous injection: high-performance liquid chromatography/tandem mass spectrometry (United States)

    Furlong, Edward T.; Noriega, Mary C.; Kanagy, Christopher J.; Kanagy, Leslie K.; Coffey, Laura J.; Burkhardt, Mark R.


    This report describes a method for the determination of 110 human-use pharmaceuticals using a 100-microliter aliquot of a filtered water sample directly injected into a high-performance liquid chromatograph coupled to a triple-quadrupole tandem mass spectrometer using an electrospray ionization source operated in the positive ion mode. The pharmaceuticals were separated by using a reversed-phase gradient of formic acid/ammonium formate-modified water and methanol. Multiple reaction monitoring of two fragmentations of the protonated molecular ion of each pharmaceutical to two unique product ions was used to identify each pharmaceutical qualitatively. The primary multiple reaction monitoring precursor-product ion transition was quantified for each pharmaceutical relative to the primary multiple reaction monitoring precursor-product transition of one of 19 isotope-dilution standard pharmaceuticals or the pesticide atrazine, using an exact stable isotope analogue where possible. Each isotope-dilution standard was selected, when possible, for its chemical similarity to the unlabeled pharmaceutical of interest, and added to the sample after filtration but prior to analysis. Method performance for each pharmaceutical was determined for reagent water, groundwater, treated drinking water, surface water, treated wastewater effluent, and wastewater influent sample matrixes that this method will likely be applied to. Each matrix was evaluated in order of increasing complexity to demonstrate (1) the sensitivity of the method in different water matrixes and (2) the effect of sample matrix, particularly matrix enhancement or suppression of the precursor ion signal, on the quantitative determination of pharmaceutical concentrations. Recovery of water samples spiked (fortified) with the suite of pharmaceuticals determined by this method typically was greater than 90 percent in reagent water, groundwater, drinking water, and surface water. Correction for ambient environmental

  4. Injection MD

    CERN Document Server

    Bartmann, W; Bracco, C; Drosdal, L; Gianfelice, E; Goddard, B; Kain, V; Papaphilippou, Y; Vanbavinckhove, G


    This note summarizes the results obtained at injection during the 2nd MD block and the floating MD block in July. Highlights are presented for injection in the LHC with the Q20 SPS optics, influence of the supercycle and injection with 25 ns bunch spacing. Beams were successfully injected into the LHC using the Q20 optics [1, 3]. Small corrections were needed to steer the beam in the transfer lines. Dispersion measurements were conducted for both beams. The horizontal normalized dispersion in TI2 was a factor 2 smaller for Q20 with respect to Q26, for TI8 on the other hand the opposite was observed. The results for injection loss dependency on super cycle composition show only a small increase in losses for beam 2. The losses observed must therefore mainly come from other sources such as shot-by-shot stability or quality of scraping. For the injection with 25 ns bunch spacing bunches were injected for both beams. For B1 up to the maximum of 288 bunches. For B2 on the other only up to 144 bunches were injected...

  5. Computational fluid dynamics simulation of the combustion process, emission formation and the flow field in an in-direct injection diesel engine

    Directory of Open Access Journals (Sweden)

    Barzegar Ramin


    Full Text Available In the present paper, the combustion process and emission formation in the Lister 8.1 I.D.I Diesel engine have been investigated using a Computational Fluid Dynamics (CFD code. The utilized model includes detailed spray atomization, mixture formation and distribution model which enable modeling the combustion process in spray/wall and spray/swirl interactions along with flow configurations. The analysis considers both part load and full load states. The global properties are presented separately resolved for the swirl chamber (pre-chamber and the main chamber. The results of model verify the fact that the equal amount of the fuel is burned in the main and pre-chamber at full load state while at part load the majority of the fuel is burned in the main chamber. Also, it is shown that the adherence of fuel spray on the pre-chamber walls is due to formation of a stagnation zone which prevents quick spray evaporation and plays an important role in the increase of soot mass fractions at this zone at full load conditions. The simulation results, such as the mean in-cylinder pressure, heat release rate and exhaust emissions are compared with the experimental data and show good agreement. This work also demonstrates the usefulness of multidimensional modeling for complex chamber geometries, such as in I.D.I Diesel engines, to gain more insight into the flow field, combustion process and emission formation.

  6. Subcutaneous Injections

    DEFF Research Database (Denmark)

    Thomsen, Maria

    This thesis is about visualization and characterization of the tissue-device interaction during subcutaneous injection. The tissue pressure build-up during subcutaneous injections was measured in humans. The insulin pen FlexTouchr (Novo Nordisk A/S) was used for the measurements and the pressure...... build-up was evaluated indirectly from the changes in the flow rate between subcutaneous injections and air injections. This method enabled the tissue counter pressure to be evaluated without a formal clinical study approval. The measurements were coupled to a model for the pressure evolution...... in subcutaneous tissue, based on mass conservation and flow in a porous medium. From the measurements the flow permeability and bulk modulus of the tissue were determined. In the adipose tissue the drug forms a bolus from where it is absorbed by the blood capillaries. The spatial distribution of the injected...

  7. Enhanced direct-modulated bandwidth of 37 GHz by a multi-section laser with a coupled-cavity-injection-grating design

    DEFF Research Database (Denmark)

    Bach, L.; Kaiser, W.; Reithmaier, J.P.;


    Using a new multi-section laser concept based on a coupled-cavity-injection-grating design, the material related intrinsic 3 dB modulation bandwidth can be enhanced up to 37 GHz for a 1.5 mm long device.......Using a new multi-section laser concept based on a coupled-cavity-injection-grating design, the material related intrinsic 3 dB modulation bandwidth can be enhanced up to 37 GHz for a 1.5 mm long device....

  8. The burn wound inflammatory response is influenced by midazolam. (United States)

    Babcock, George F; Hernandez, Laura; Yadav, Ekta; Schwemberger, Sandy; Dugan, Amy


    Burn patients requiring hospitalization are often treated for anxiety with benzodiazepines (BDZs). Benzodiazepines are reported to influence immune system function. Immune system alterations are a major cause of burn-induced mortality. We wanted to determine whether the BDZ, midazolam given daily at an anxiolytic dose, had any influence on the burn injury-induced inflammatory response in the blood and wound. Mice received a 15% total body surface area flame burn and received either midazolam 1 mg/kg i.p. or saline 0.1 ml daily. Blood and skin wounds were harvested 24 h after injection on post-burn day 2, 3, 7, or 8. Mice treated with midazolam had significantly lower serum IL-1β (p=0.002), TNF-α (p=0.002), IL-6 (p=0.016), IL-10 (p=0.009), and TGF-β (p=0.004) than saline-treated mice, with little impact on serum chemokine levels. In the wound, TNF-α and IL-10 were the only cytokines significantly influenced by the drug, being lower (p=0.018) and higher (p=0.006), respectively. The chemokines in the wound influenced significantly by midazolam were MIP-1α, MIP-1β, and MIP-2 while MCP-1 and KC were not. There were more inflammatory cells at the burn wound margin in midazolam-treated mice on post-burn day 3. Although serum nitrate/nitrite was significantly increased by midazolam (p=0.03), both eNOS and iNOS mRNA expression in the wound were similar to the saline group. We found that midazolam given daily after burn injury significantly influenced the inflammatory response. The clinical implications of these findings on wound healing and shock following burn injury, especially larger burns, deserve further investigation.

  9. Psychiatric aspects of burn

    Directory of Open Access Journals (Sweden)

    Dalal P


    Full Text Available Burn injuries and their subsequent treatment cause one of the most excruciating forms of pain imaginable. The psychological aspects of burn injury have been researched in different parts of the world, producing different outcomes. Studies have shown that greater levels of acute pain are associated with negative long-term psychological effects such as acute stress disorder, depression, suicidal ideation, and post-traumatic stress disorder for as long as 2 years after the initial burn injury. The concept of allostatic load is presented as a potential explanation for the relationship between acute pain and subsequent psychological outcomes. A biopsychosocial model is also presented as a means of obtaining better inpatient pain management and helping to mediate this relationship.

  10. Characterization of facial burns from maxillofacial surgery. Cienfuegos 2005 - 2007

    Directory of Open Access Journals (Sweden)

    Eduardo Duarte Marrero


    Full Text Available Background: A descriptive study and retrospective study with 87 patients for facial burns, were treated at the Burn Service of the Hospital General Universitario "Dr. Gustavo Lima Aldereguía "Cienfuegos between January 2005 and September 2007. Objective: To characterize the care of patients with facial burns to help develop knowledge, attitudes and skills medical - surgery in the maxillofacial surgeon. Method: the source of information used were the records of patient care in the emergency department Burned Service and these data were selected that identified the patients as well as other related directly with facial burns. For each patient, more severe burning classified according to their size and depth. Results: In this study facial burns were more frequent in females aged 16 to 34 years, the most common cause of these lesions was in contact with boiling liquids as the predominant type skin burns, with extensions between 2 and 4% of the face area. In 44 patients affected centers facial structures, so predominant involvement of the ears. The priest most used in the facial region was the stop with silver sulfadiazine. Approximately 50% of patients were affected in the organs of sense, particularly in the ears. Conclusion: The traumatic facial burns are more severe conditions than any other location for the possible commitment to the airways.

  11. Bacteriological profile of burn patients at Yekatit 12 Hospital Burn ...

    African Journals Online (AJOL)


    injuries, creating a formidable public health problem. (3). Despite major ... change with time. Thus, to have an in-depth knowledge .... Table 4: Antibiotic resistance pattern of bacterial isolates from burn wound at Yekatit 12 hospital burn center.

  12. Evaluating aerosol impacts on Numerical Weather Prediction in two extreme dust and biomass-burning events (United States)

    Remy, Samuel; Benedetti, Angela; Jones, Luke; Razinger, Miha; Haiden, Thomas


    The WMO-sponsored Working Group on Numerical Experimentation (WGNE) set up a project aimed at understanding the importance of aerosols for numerical weather prediction (NWP). Three cases are being investigated by several NWP centres with aerosol capabilities: a severe dust case that affected Southern Europe in April 2012, a biomass burning case in South America in September 2012, and an extreme pollution event in Beijing (China) which took place in January 2013. At ECMWF these cases are being studied using the MACC-II system with radiatively interactive aerosols. Some preliminary results related to the dust and the fire event will be presented here. A preliminary verification of the impact of the aerosol-radiation direct interaction on surface meteorological parameters such as 2m Temperature and surface winds over the region of interest will be presented. Aerosol optical depth (AOD) verification using AERONET data will also be discussed. For the biomass burning case, the impact of using injection heights estimated by a Plume Rise Model (PRM) for the biomass burning emissions will be presented.

  13. Burns in Turkish children and adolescents: nine years of experience. (United States)

    Sakallioğlu, A E; Başaran, O; Tarim, A; Türk, E; Kut, A; Haberal, M


    The aim of this study was to describe information about burns that occur in children and adolescents in Turkey. The subjects were 362 patients whom were younger than 18 years who were treated at 3 burn centers in 2 different regions of Turkey between 1997 and 2005. The data collected for each case were age, gender, place of residence, cause and extent of burn, body sites affected, environment in which the injury occurred, interval from injury to arrival at a burn center, hospitalization status (inpatient versus outpatient), surgical treatment, and mortality. The 362 patients comprised 35.5% of all 1021 burn victims admitted during the study period. There were 183 boys and 179 girls (ratio 1:0.98) and the mean total body surface area burned was 17.7+/-16.5%. The highest proportion of patients were in the 1-6 years age group. Non-bath (not immersed) hot water scalding (216 cases, 59.7%) was the leading burn cause. The most common environment in which burn injury occurred was the home. The trunk was the body site most frequently affected (62.7%). 241 (66.6%) subjects lived in urban environments and 121 (33.4%) lived in rural areas. 171 patients (47.2%) were taken directly to the burn units, whereas the others (52.8%) were referred from other medical centers. 124 (34.3%) subjects were treated as outpatients and 238 (65.7%) were hospitalized. The overall mortality rate was 8.6% (31 deaths). Of the 238 inpatients, 92 (38.7%) were treated with daily dressings only, 128 (53.8%) required debridement, and 75 (31.5%) needed both debridement and grafting. Every country needs a nationwide public education system that is aimed at preventing burns and ensuring that burn victims receive proper first aid and age-appropriate, specialized burn care.

  14. Using Direct Metal Deposition to Fabricate Mold Plates for an Injection Mold Machine Allowing for the Evaluation of Cost Effective Near-Sourcing Opportunities in Larger, High Volume Consumer Products

    Energy Technology Data Exchange (ETDEWEB)

    Duty, Chad E [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Groh, Bill [Radio Systems Corporation, Knoxville, TN (United States)


    ORNL collaborated with Radio Systems Corporation to investigate additive manufacturing (AM) of mold plates for plastic injection molding by direct metal deposition. The team s modelling effort identified a 100% improvement in heat transfer through use of conformal cooling lines that could be built into the mold using a revolutionary design enabled by additive manufacturing. Using the newly installed laser deposition system at the ORNL Manufacturing Demonstration Facility (MDF) a stainless steel mold core was printed.

  15. Ventilator associated pneumonia in major paediatric burns. (United States)

    Rogers, Alan David; Deal, Cailin; Argent, Andrew Charles; Hudson, Donald Anthony; Rode, Heinz


    More than three-quarters of deaths related to major burns are a consequence of infection, which is frequently ventilator associated pneumonia (VAP). A retrospective study was performed, over a five-year period, of ventilated children with major burns. 92 patients were included in the study; their mean age was 3.5 years and their mean total body surface area burn was 30%. 62% of the patients sustained flame burns, and 31% scalds. The mean ICU stay was 10.6 days (range 2-61 days) and the mean ventilation time was 8.4 days (range 2-45 days). There were 59 documented episodes of pneumonia in 52 patients with a rate of 30 infections per 1000 ventilator days. Length of ventilation and the presence of inhalational injury correlate with the incidence of VAP. 17.4% of the patients died (n=16); half of these deaths may be attributed directly to pneumonia. Streptococcus pneumonia, Pseudomonas aeruginosa, Acinetobacter baumanii and Staphylococcus aureus were the most prominent aetiological organisms. Broncho-alveolar lavage was found to be more specific and sensitive at identifying the organism than other methods. This study highlights the importance of implementing strictly enforced strategies for the prevention, detection and management of pneumonia in the presence of major burns.

  16. An assessment of burn care professionals' attitudes to major burn.

    LENUS (Irish Health Repository)

    Murphy, A D


    The resuscitation of severe burn remains a controversial area within the burn care profession. There is ongoing debate as to what percentage burn is associated with a sufficient quality of life to support initial resuscitation efforts. We conducted a survey of delegates at the 39th Annual Meeting of the British Burns Association (2005), regarding attitudes towards resuscitation following major burns. Respondents were asked the maximum percentage total body surface area (TBSA) burn beyond which they would not wish to be resuscitated. They were also asked what maximum TBSA they perceived to be commensurate with an acceptable quality of life (QOL). One hundred and forty three of 300 delegates responded to the questionnaire. Thirty three percent of respondents would not wish to be resuscitated with 50-75% TBSA burns or greater. A further 35% would not wish to have life-sustaining intervention with 75-95% TBSA burns or greater. The remaining 32% indicated that they would not want resuscitation with TBSA burns>95%. Regardless of TBSA affected, 16% would not wish resuscitation if they had full thickness facial burns, a further 10% did not want resuscitation if both their hands and faces were affected. Our survey demonstrates the diversity of personal preference amongst burn care professionals. This would suggest that a unifying philosophy regarding the resuscitation of extensive burns will remain elusive.

  17. Analysis of transient flows in gasoline direct injection systems: effects on unsteady air entrainment by the spray; Analyse des ecoulements transitoires dans les systemes d'injection directe essence: effets sur l'entrainement d'air instationnaire du spray

    Energy Technology Data Exchange (ETDEWEB)

    Delay, G.


    The aim of this study is to determine instantaneous liquid flow rate oscillations effect on non stationary air entrainment of an injector conical spray (Gasoline Direct Injection). The tools we use are either experimental or numerical ones. An instantaneous flow rate determination method is used. It is based on pulsated flows physics and only requires the velocity at the centerline of a pipe mounted just before the injector. So, it is possible to 'rebuild' the instantaneous velocity distributions and then to get the instantaneous liquid flow rate (Laser Doppler Anemometry measurements). A mechanical and hydraulics modeling software (AMESim) is necessary to get injector outlet flow rate. Simulations are validated by both 'rebuilding' method results and common rail pressure measurements. Fluorescent Particle Image Velocimetry (FPIV), suited to dense two -phase flows, is used to measure air flow around and inside the conical spray. Velocity measurements close to the spray frontier are used to compute instantaneous air entrainment. Considering droplets momentum exchange with air and thanks to droplets diameters and liquid velocities measurements at the nozzle exit, a transient air entrainment model is proposed according to FPIV measurements. (author)

  18. Metoclopramide Injection (United States)

    ... and feeling of fullness that lasts long after meals. Metoclopramide injection is also used to prevent nausea ... tranylcypromine (Parnate); narcotic medications for pain; sedatives; sleeping pills; tetracycline (Bristacycline, Sumycin); tranquilizers. Your doctor may need ...

  19. Ramucirumab Injection (United States)

    ... dose of ramucirumab injection. Tell your doctor or nurse if you experience any of the following while you receive ramucirumab: uncontrollable shaking of a part of the body; back pain or spasms; chest pain and tightness; chills; flushing; ...

  20. Alemtuzumab Injection (United States)

    Alemtuzumab injection is used to treat B-cell chronic lymphocytic leukemia (a slowly developing cancer in which ... of white blood cell accumulate in the body). Alemtuzumab is in a class of medications called monoclonal ...

  1. Ferumoxytol Injection (United States)

    Ferumoxytol injection is used to treat iron-deficiency anemia (a lower than normal number of red blood ... pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or ...

  2. Fludarabine Injection (United States)

    Fludarabine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white ... a reliable method of birth control to prevent pregnancy during this time. Talk to your doctor for ...

  3. Insulin Injection (United States)

    ... or buttocks. Do not inject insulin into muscles, scars, or moles. Use a different site for each ... you are using insulin.Alcohol may cause a decrease in blood sugar. Ask your doctor about the ...

  4. Tigecycline Injection (United States)

    ... in a person who was not in the hospital), skin infections, and infections of the abdomen (area between the ... that developed in people who were in a hospital or foot infections in people who have diabetes. Tigecycline injection is ...

  5. Golimumab Injection (United States)

    Golimumab injection is used alone or with other medications to relieve the symptoms of certain autoimmune disorders ( ... did not help or could not be tolerated. Golimumab is in a class of medications called tumor ...

  6. Albiglutide Injection (United States)

    ... will develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). ... symptoms or those listed in the IMPORTANT WARNING section, stop using albiglutide injection and call your doctor ...

  7. Dexamethasone Injection (United States)

    ... body tissues,) gastrointestinal disease, and certain types of arthritis. Dexamethasone injection is also used for diagnostic testing. ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  8. Hydrocortisone Injection (United States)

    ... own organs), gastrointestinal disease, and certain types of arthritis. Hydrocortisone injection is also used to treat certain ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  9. Methylprednisolone Injection (United States)

    ... own organs), gastrointestinal disease, and certain types of arthritis. Methylprednisolone injection is also used to treat certain ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  10. Glatiramer Injection (United States)

    ... To inject glatiramer, follow these steps: Remove one blister pack from the carton of glatiramer syringes and place ... paper label and remove the syringe from the blister pack. Check your prefilled syringe to be sure it ...

  11. Dexrazoxane Injection (United States)

    ... that are used to treat or prevent certain side effects that may be caused by chemotherapy medications. Dexrazoxane injection (Zinecard) is used to prevent or decrease heart damage caused by doxorubicin in women who are ...

  12. Cidofovir Injection (United States)

    Cidofovir injection is used along with another medication (probenecid) to treat cytomegaloviral retinitis (CMV retinitis) in people with acquired immunodeficiency syndrome (AIDS). Cidofovir is in a class of medications called antivirals. ...

  13. Brivaracetam Injection (United States)

    ... older. Brivaracetam in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in ... older (about 1 in 500 people) who took anticonvulsants like brivaracetam injection to treat various conditions during ...

  14. Diphenhydramine Injection (United States)

    ... not to use diphenhydramine injection if you are breastfeeding because of the risk of harm to infants.tell your doctor if you have or have ever had asthma or other types of lung disease; glaucoma (a ...

  15. Cefazolin Injection (United States)

    ... valve, respiratory tract (including pneumonia), biliary tract, and urinary tract infections. Cefazolin injection also may be used before, during, ... to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( ...

  16. Ceftazidime Injection (United States)

    ... skin, blood, bone, joint, female genital tract, and urinary tract infections. Ceftazidime injection is in a class of medications ... to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( ...

  17. Fluconazole Injection (United States)

    ... and fungal infections of the eye, prostate (a male reproductive organ), skin and nails. Fluconazole injection is ... Motrin, others) and naproxen (Aleve, Anaprox, Naprelan); oral contraceptives (birth control pills); oral medication for diabetes such ...

  18. Moxifloxacin Injection (United States)

    ... available.Moxifloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause ... you are allergic to moxifloxacin, other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available ...

  19. Levofloxacin Injection (United States)

    ... available. Levofloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. ... severe reaction to levofloxacin; any other quinolone or fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available ...

  20. Ciprofloxacin Injection (United States)

    ... available. Ciprofloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. ... reaction to ciprofloxacin or any other quinolone or fluoroquinolone antibiotic such as gatifloxacin (Tequin) (not available in the ...

  1. Alirocumab Injection (United States)

    ... further decrease the amount of low-density lipoprotein (LDL) cholesterol ('bad cholesterol') in the blood. Alirocumab injection is ... antibodies. It works by blocking the production of LDL cholesterol in the body to decrease the amount of ...

  2. Chloramphenicol Injection (United States)

    ... an arm or leg sudden changes in vision pain with eye movement Chloramphenicol injection may cause a condition called gray syndrome in premature and newborn infants. There have also been reports of gray ...

  3. Back Bay Wilderness burning support (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a memorandum concerning prescribed burns between members of the Bureau of Sport Fisheries and Wildlife. It states that burning should be supported...

  4. Phoenix Society for Burn Survivors (United States)

    ... Medical Professionals Phoenix Society is the leader in connecting the burn recovery community and creating resources for survivors. Since 1977, we have partnered with survivors, families, health care professionals, burn centers, and the fire ...

  5. Hair bleaching and skin burning

    National Research Council Canada - National Science Library

    Forster, K; Lingitz, R; Prattes, G; Schneider, G; Sutter, S; Schintler, M; Trop, M


    .... We report a unique case of a 16-yr-old girl who suffered full-thickness chemical and thermal burns to the nape of her neck and superficial burns to the occiput after her hair had been dyed blond...

  6. The year in burns 2008. (United States)

    Wolf, Steven E


    For 2008, approximately 1200 original burn research articles were published in scientific journals using the English language. This article reviews those with the most impact on burn treatment according to the Editor of one of the major journals (Burns). As in the previous year's review, articles were divided into the following topic areas: epidemiology, wound characterisation, critical care physiology, inhalation injury, infection, metabolism and nutrition, psychological considerations, pain management, rehabilitation, and burn reconstruction. Each selected article is mentioned briefly with editorial comment.

  7. TIRES, OPEN BURNING (United States)

    The chapter describes available information on the health effects from open burning of rubber tires. It concentrates on the three known sources of detailed measurements: (1) a small-scale emissions characterization study performed by the U.S. EPA in a facility designed to simulat...

  8. Chemical burn or reaction (United States)

    ... this page: // Chemical burn or reaction To use the sharing features on this page, please enable JavaScript. Chemicals that touch skin can lead to a reaction on the skin, throughout the body, or both. ...


    Institute of Scientific and Technical Information of China (English)


    Objective Endotoxin as the inciting agentof cytokines and other mediators, whose highlevel expression correlates with the septicshock and MOF, has been the one of leadingcauses of death in ICU. Methods For treatingsepsis and MOF caused by endotoxin, the anti-lipid A of LPS antibody was used. 19 burned

  10. Effects of Direct Fuel Injection Strategies on Cycle-by-Cycle Variability in a Gasoline Homogeneous Charge Compression Ignition Engine: Sample Entropy Analysis

    Directory of Open Access Journals (Sweden)

    Jacek Hunicz


    Full Text Available In this study we summarize and analyze experimental observations of cyclic variability in homogeneous charge compression ignition (HCCI combustion in a single-cylinder gasoline engine. The engine was configured with negative valve overlap (NVO to trap residual gases from prior cycles and thus enable auto-ignition in successive cycles. Correlations were developed between different fuel injection strategies and cycle average combustion and work output profiles. Hypothesized physical mechanisms based on these correlations were then compared with trends in cycle-by-cycle predictability as revealed by sample entropy. The results of these comparisons help to clarify how fuel injection strategy can interact with prior cycle effects to affect combustion stability and so contribute to design control methods for HCCI engines.

  11. Modern management of paediatric burns

    African Journals Online (AJOL)


    Mar 1, 2010 ... Jackson's. 3-dimensional burn wound model describes 3 zones: • a central zone ... the burn.7 Care must be taken not to induce hypothermia in larger burns – especially in .... Fluid therapy thereafter consists of 2 components ...

  12. A Goniometry Paradigm Shift to Measure Burn Scar Contracture in Burn Patients (United States)


    seven joints of interest with a predilection to develop burn scar contracture. Specific Aim 2: To statistically associate the severity of burn scar...measurements in a burn population across  six (6) joints of interest in  eleven  (11) single directions. • Specific Aim 2: To compare the average reduction in...the six (6) joints of interest in  eleven  (11) single directions. •Specific Aim 3: To examine the association between the reduction in the joint range

  13. Burn epidemiology and cost of medication in paediatric burn patients. (United States)

    Koç, Zeliha; Sağlam, Zeynep


    Burns are common injuries that cause problems to societies throughout the world. In order to reduce the cost of burn treatment in children, it is extremely important to determine the burn epidemiology and the cost of medicines used in burn treatment. The present study used a retrospective design, with data collected from medical records of 140 paediatric patients admitted to a burn centre between 1 January 2009 and 31 December 2009. Medical records were examined to determine burn epidemiology, medication administered, dosage, and duration of use. Descriptive statistical analysis was completed for all variables; chi-square was used to examine the relationship between certain variables. It was found that 62.7% of paediatric burns occur in the kitchen, with 70.7% involving boiling water; 55.7% of cases resulted in third-degree burns, 19.3% required grafting, and mean duration of hospital stay was 27.5 ± 1.2 days. Medication costs varied between $1.38 US dollars (USD) and $14,159.09, total drug cost was $46,148.03 and average cost per patient was $329.63. In this study, the medication cost for burn patients was found to be relatively high, with antibiotics comprising the vast majority of medication expenditure. Most paediatric burns are preventable, so it is vital to educate families about potential household hazards that can be addressed to reduce the risk of a burn. Programmes are also recommended to reduce costs and the inappropriate prescribing of medication.

  14. Prehospital cooling of severe burns: Experience of the Emergency Department at Edendale Hospital, KwaZulu-Natal, South Africa. (United States)

    Fiandeiro, D; Govindsamy, J; Maharaj, R C


    Early cooling with 10 - 20 minutes of cool running water up to 3 hours after a burn has a direct impact on the depth of the burn and therefore on the clinical outcome of the injury. An assessment of the early cooling of burns is essential to improve this aspect of burns management. To assess the rates and adequacy of prehospital cooling received by patients with severe burns before presentation to the Emergency Department (ED) at Edendale Hospital, Pietermaritzburg, South Africa. Patients with inadequate prehospital cooling who presented to the ED within 3 hours were also identified. A retrospective reviewof the burns database for all the patients with severe burns admitted from the ED at Edendale Hospital from September 2012 to August 2013 was undertaken. Demographic details, characteristics and timing of the burns, and presentation were correlated with burn cooling. Ninety patients were admitted with severe burns. None received sufficient cooling of their burns, 25.6% received cooling of inadequate duration, and 32.3% arrived at the ED within 3 hours after the burn with either inadequate or no cooling. The median time to presentation to the ED after the burn was 260 minutes. Appropriate cooling of severe burns presenting to Edendale Hospital is inadequate. Education of the community and prehospital healthcare workers about the iiportance of early appropriate cooling of severe burns is required. Many patients would benefit from cooling of their burns in the ED, and facilities should be provided for this vital function.

  15. Steady state Ab-initio Theory of Lasers with Injected Signals

    CERN Document Server

    Cerjan, Alexander


    We present an ab-initio treatment of steady-state lasing with injected signals that treats both multimode lasing and spatial hole burning, and describes the transition to injection locking or partial locking in the multimode case. The theory shows that spatial hole burning causes a shift in the frequency of free-running laser modes away from the injection frequency, in contrast to standard approaches.

  16. Characteristics of paediatric burns in Sichuan province: epidemiology and prevention. (United States)

    Liu, Yong; Cen, Ying; Chen, Jun-Jie; Xu, Xue-Wen; Liu, Xiao-Xue


    This study analysed the epidemiology of paediatric burns in Sichuan province, China, for the formulation of prevention programmes for this population. A retrospective review was performed of paediatric patients admitted to the Burn Centre of West China Hospital during 2003-2009, including patient demographics, burn aetiology, time and place of burn, rural or urban population, and education level and burn knowledge of the patients' guardians. A total of 1387 paediatric burn patients, mean age 3.21 years (range 0-14 years) were admitted. The majority (72.1%) were 0-3 years old, and the male/female ratio was 2.39:1. Most common aetiologies were scalds (81.3%), flames (17.1%), and electricity (1.3%), while chemical burns were rare. The ratio of indoor versus outdoor location was 4.93:1, and the rural/urban ratio was 4.03:1. Burns were classified as: total burn surface area (TBSA) ranging from 0% to 5%, (23.9% of patients); TBSA between 5% and 15% (33.2%); TBSA between 15% and 25% (29.8%); TBSA greater than 25% (13.1%). There was a higher prevalence from April to September, and the peak times were mealtime and bathtime. The education level was lower in the rural group. Both urban and rural groups had little knowledge of first aid for burns. Burn prevention programmes should promote improved living conditions, with prevention education addressed directly to the guardians of children. Copyright © 2011. Published by Elsevier Ltd.

  17. Fire walking in Singapore-a study of the distribution of burns. (United States)

    Sayampanathan, Andrew A


    Fire walking is a religious ritual practiced by predominantly Indians and some Chinese living in Singapore. Eighteen new cases of burns, directly related to a firewalking ceremony on 05 October 09, were studied as to the pattern of burns. Burns on the soles of the feet occurred in 17 patients. All these injuries were superficial or partial thickness burns. There were no deep dermal burns. The extent of burns ranged from 0.25% to 1.5% of body surface area. Burns due to falls accounted for one casualty. He sustained a mixture of deep dermal and partial thickness burns, and the extent of burns was 20% of body surface area. A new classification for the distribution of burns related to fire walking was developed based on the mechanism of injury. It was predictive of the anatomical distribution of burns, the extent of burns (in terms of body surface area), the depth of burns and the general severity of the injury: Copyright © 2010 Elsevier Ltd and ISBI. All rights reserved.

  18. Fungal infections in burns: Diagnosis and management

    Directory of Open Access Journals (Sweden)

    Capoor Malini


    Full Text Available Burn wound infection (BWI is a major public health problem and the most devastating form of trauma worldwide. Fungi cause BWI as part of monomicrobial or polymicrobial infection, fungaemia, rare aggressive soft tissue infection and as opportunistic infections. The risk factors for acquiring fungal infection in burns include age of burns, total burn size, body surface area (BSA (30-60%, full thickness burns, inhalational injury, prolonged hospital stay, late surgical excision, open dressing, artificial dermis, central venous catheters, antibiotics, steroid treatment, long-term artificial ventilation, fungal wound colonisation (FWC, hyperglycaemic episodes and other immunosuppressive disorders. Most of the fungal infections are missed owing to lack of clinical awareness and similar presentation as bacterial infection coupled with paucity of mycology laboratories. Expedient diagnosis and treatment of these mycoses can be life-saving as the mortality is otherwise very high. Emergence of resistance in non-albicans Candida spp., unusual yeasts and moulds in fungal BWI, leaves very few fungi susceptible to antifungal drugs, leaving many patients susceptible. There is a need to speciate fungi as far as the topical and systemic antifungal is concerned. Deep tissue biopsy and other relevant samples are processed by standard mycological procedures using direct microscopy, culture and histopathological examination. Patients with FWC should be treated by aggressive surgical debridement and, in the case of fungal wound infection (FWI, in addition to surgical debridement, an intravenous antifungal drug, most commonly amphotericin B or caspofungin, is prescribed followed by de-escalating with voriconazole or itraconazole, or fluconazole depending upon the species or antifungal susceptibility, if available. The propensity for fungal infection increases, the longer the wound is present. Therefore, the development of products to close the wound more rapidly

  19. The year in burns 2011. (United States)

    Wolf, Steven E; Arnoldo, Brett D


    For 2011, approximately 1746 original research articles in burns were published in English in scientific journals. This article reviews those with the most potential impact on for burn therapeutics and outcomes according to the Editor of one of the major journals (Burns) and his colleague. As done previously, articles were found and divided into these topic areas: epidemiology of injury and burn prevention, wound and scar characterisation, acute care and critical care, inhalation injury, infection, psychological considerations, pain and itching management, rehabilitation and long-term outcomes, and burn reconstruction. Each selected article is mentioned briefly with editorial comment.

  20. Intracytoplasmic Sperm Injection (ICSI) (United States)

    ... sperm must attach to the outside of the egg. Once attached, the sperm pushes through the outer layer to the inside ... in vitro fertilization (IVF) to help fertilize the egg. During ICSI, a single sperm is injected directly into the cytoplasm the egg. ...

  1. 点燃式缸内直喷甲醇发动机甲醛和未燃甲醇排放特性%Formaldehyde and unburned methanol emissions from a spark-ignition direct-injection methanol engine

    Institute of Scientific and Technical Information of China (English)

    宫长明; 张自雷; 贾京龙; 崔峰云; 郑伟


    The effects of methanol injection timing, ignition timing and excess air ratio on formaldehyde and unburned methanol emissions from a spark-ignition direct-injection methanol engine under homogenous combustion mode were investigated experimentally by means of a measurement method in which the gas chromatography and the liquid chromatography were used to separate and measure formaldehyde and methanol. The results show that the methanol injection timing, ignition timing and excess air ratio affect significantly the formaldehyde and unburned methanol emissions from a spark- ignition directqnjection methanol engine. The variations in emitted formaldehyde and unburned methanol show opposite tendencies with the variations in the methanol injection timing, ignition timing and excess air ratio. Retarding methanol injection timing, advancing ignition timing and using lean mixture decrease formaldehyde emission.%基于气相色谱和液相色谱相结合的甲醛和甲醇测量方法,试验研究了点燃式缸内直喷甲醇发动机甲醇喷射正时、点火正时和过量空气系数在均质燃烧模式下对甲醛和未燃甲醇排放的影响。试验结果表明,甲醇喷射正时、点火正时和过量空气系数对该发动机甲醛和未燃甲醇排放有显著影响,并且甲醛和未燃甲醇排放随喷射正时、点火正时和过量空气系数的变化呈相反的变化趋势。推迟喷射甲醇、提前点火及采用稀混合气可以降低甲醛排放。

  2. PS injection area

    CERN Multimedia


    Looking against the direction of protons in the main ring (left): the beam coming from the linac 1 either goes to the booster (on the right) or is deflected towards the PS to be directly injected into section 26 (facing the camera). Also shown the start of the TT2 line, ejected from straight section 16 to go towards the ISR passing over the beam line from the linac. (see Photo Archive 7409009)

  3. FI/SI on-line solvent extraction/back extraction preconcentration coupled to direct injection nebulization inductively coupled plasma mass spectrometry for determination of copper and lead

    DEFF Research Database (Denmark)

    Wang, Jianhua; Hansen, Elo Harald


    at a sample flow rate of 6.0 ml/min The precisions (RSD) at the 0.2 mug/1 level were 4.4% (Cu) and 4.8% (Pb), respectively. The applicability of the procedure is demonstrated for the determination of copper and lead in three certified reference materials and a urine sample.......An automated sequential injection on-line preconcentration procedure for determination of trace levels of copper and lead via solvent extraction/back extraction coupled to ICP-MS is described. In citrate buffer of pH 3, neutral complexes between the analytes and the chelating reagent, ammonium...

  4. 奥迪FSI直喷式汽油机的燃烧系统%Audi FSI Gasoline Direct Injection Combustion System

    Institute of Scientific and Technical Information of China (English)



    @@ 奥迪FSI发动机的发展历史FSI(Fuet Stratified Injection,直译为燃油分层喷射)是大众集团奥迪公司开发的气流引导型(air guided)GDI发动机系列.大众集团最早于2000年底第一次用1.4L/77kW的FSI发动机配备路波(Lupo)车,百公里油耗低于5L.

  5. History of burns: The past, present and the future

    Directory of Open Access Journals (Sweden)

    Kwang Chear Lee


    Full Text Available Burn injuries are one of the most common and devastating afflictions on the human body. In this article we look back at how the treatment of burns has evolved over the centuries from a primarily topical therapy consisting of weird and wonderful topical concoctions in ancient times to one that spans multiple scientific fields of topical therapy, antibiotics, fluid resuscitation, skin excision and grafting, respiratory and metabolic care and nutrition. Most major advances in burn care occurred in the last 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical silver therapy greatly reduced sepsis related mortality. This along with the advent of antiseptic surgical techniques, burn depth classification and skin grafting allowed the excision and coverage of full-thickness burns which resulted in greatly improved survival rates. Advancements in the methods of assessing the surface area of burns paved way for more accurate fluid resuscitation, minimising the effects of shock and avoiding fluid over-loading. The introduction of metabolic care, nutritional support and care of inhalational injuries further improved the outcome of burn patients. We also briefly discuss some future directions in burn care such as the use of cell and pharmalogical therapies.

  6. History of burns: The past, present and the future. (United States)

    Lee, Kwang Chear; Joory, Kavita; Moiemen, Naiem S


    Burn injuries are one of the most common and devastating afflictions on the human body. In this article we look back at how the treatment of burns has evolved over the centuries from a primarily topical therapy consisting of weird and wonderful topical concoctions in ancient times to one that spans multiple scientific fields of topical therapy, antibiotics, fluid resuscitation, skin excision and grafting, respiratory and metabolic care and nutrition. Most major advances in burn care occurred in the last 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical silver therapy greatly reduced sepsis related mortality. This along with the advent of antiseptic surgical techniques, burn depth classification and skin grafting allowed the excision and coverage of full-thickness burns which resulted in greatly improved survival rates. Advancements in the methods of assessing the surface area of burns paved way for more accurate fluid resuscitation, minimising the effects of shock and avoiding fluid over-loading. The introduction of metabolic care, nutritional support and care of inhalational injuries further improved the outcome of burn patients. We also briefly discuss some future directions in burn care such as the use of cell and pharmalogical therapies.

  7. Prehospital Care of Burn Patients and Trajectories on Survival. (United States)

    Kallinen, Outi; Koljonen, Virve; Tukiainen, Erkki; Randell, Tarja; Kirves, Hetti


    We sought to identify factors associated with the prognosis and survival of burn patients by analyzing data related to the prehospital treatment of burn patients transferred directly to the burn unit from the accident site. We also aimed to assess the role of prehospital physicians and paramedics providing care to major burn patients. This study included adult burn patients with severe burns treated between 2006 and 2010. Prehospital patient records and clinical data collected during treatment were analyzed, and the Injury Severity Scale (ISS) was calculated. Patients were grouped into two cohorts based on the presence or absence of a physician during the prehospital phase. Data were analyzed with reference to survival by multivariable regression model. Specific inclusion criteria resulted in a sample of 67 patients. The groups were comparable with regard to age, gender, and injury etiology. Patients treated by prehospital physicians (group 1, n = 49) were more severely injured than patients treated by paramedics (group 2, n = 18) in terms of total burn surface area (%TBSA) (32% vs. 17%, p = 0.033), ISS (25 vs. 8, p prehospital prognostic factors affecting patient outcomes. Based on the results from this study, our current EMS system is capable of identifying seriously injured burn patients who may benefit from physician attendance at the injury scene.

  8. Assessing burn depth in tattooed burn lesions with LASCA Imaging. (United States)

    Krezdorn, N; Limbourg, A; Paprottka, F J; Könneker; Ipaktchi, R; Vogt, P M


    Tattoos are on the rise, and so are patients with tattooed burn lesions. A proper assessment with regard to burn depth is often impeded by the tattoo dye. Laser speckle contrast analysis (LASCA) is a technique that evaluates burn lesions via relative perfusion analysis. We assessed the effect of tattoo skin pigmentation on LASCA perfusion imaging in a multicolour tattooed patient. Depth of burn lesions in multi-coloured tattooed and untattooed skin was assessed using LASCA. Relative perfusion was measured in perfusion units (PU) and compared to various pigment colours, then correlated with the clinical evaluation of the lesion. Superficial partial thickness burn (SPTB) lesions showed significantly elevated perfusion units (PU) compared to normal skin; deep partial thickness burns showed decreased PU levels. PU of various tattoo pigments to normal skin showed either significantly lower values (blue, red, pink) or significantly increased values (black) whereas orange and yellow pigment showed values comparable to normal skin. In SPTB, black and blue pigment showed reduced perfusion; yellow pigment was similar to normal SPTB burn. Deep partial thickness burn (DPTB) lesions in tattoos did not show significant differences to normal DPTB lesions for black, green and red. Tattoo pigments alter the results of perfusion patterns assessed with LASCA both in normal and burned skin. Yellow pigments do not seem to interfere with LASCA assessment. However proper determination of burn depth both in SPTB and DPTB by LASCA is limited by the heterogenic alterations of the various pigment colours.

  9. [Hydrofluoric acid burns]. (United States)

    Holla, Robin; Gorter, Ramon R; Tenhagen, Mark; Vloemans, A F P M Jos; Breederveld, Roelf S


    Hydrofluoric acid is increasingly used as a rust remover and detergent. Dermal contact with hydrofluoric acid results in a chemical burn characterized by severe pain and deep tissue necrosis. It may cause electrolyte imbalances with lethal consequences. It is important to identify high-risk patients. 'High risk' is defined as a total affected body area > 3% or exposure to hydrofluoric acid in a concentration > 50%. We present the cases of three male patients (26, 31, and 39 years old) with hydrofluoric acid burns of varying severity and describe the subsequent treatments. The application of calcium gluconate 2.5% gel to the skin is the cornerstone of the treatment, reducing pain as well as improving wound healing. Nails should be thoroughly inspected and possibly removed if the nail is involved, to ensure proper healing. In high-risk patients, plasma calcium levels should be evaluated and cardiac monitoring is indicated.

  10. [Burning mouth syndrome (glossalgia)]. (United States)


    Burning mouth syndrome (glossalgia) is manifested by oral pin and tingling sensations, numbness and even burning and severe pains, more frequently in the tongue. Unpleasant sensations may involve the anterior two thirds of the tongue or be extended to the front part of the hard palate and the mucous membrane of the lower lip. This condition is characterized by "mirror" and "food dominant" symptoms, disordered salivation, dysgeusia, or psychological disorders. The disease shows a chronic course. Its etiology may be multifactorial. There are no universally accepted diagnostic criteria; the diagnosis of glossalgia is made to rule out all other causes. A thorough examination should be conducted to establish a differential diagnosis. Glossalgia occurs primarily in middle-aged and elderly people. Women get sick much more frequently than men of the same age. Glossalgia remains difficult to treat. Continuous symptomatic treatment and follow-up help relieve its symptoms.

  11. Emission Characteristics of Direct Injection Natural Gas Engine Using Rapid Compression Machine%用快速压缩装置研究直喷式天然气发动机排放特性

    Institute of Scientific and Technical Information of China (English)

    黄佐华; 曾科; 杨中乐


    使用快速压缩装置进行了直喷式天然气发动机排放特性的研究.测量了三种不同方式下的排放,并与均相混合气燃烧情况进行了对比.实验结果表明,在宽广的当量比范围内,天然气直喷方式的燃烧效率高于0.95.由于混合气的分层燃烧,天然气喷射方式在宽广的当量比范围内保持较低的HC排放量,同等功率下的低CO2排放量,低NOx排放量,其NOx排放在理论当量比处的降低更为明显.直喷天然气发动机既具备柴油机发动机效率高的特点,又具备预混燃烧发动机排放低的特点.%Investigation of emission characteristics of a direct injection natural gas engine is carried out using a rapid compression machine.The emissions of three injection modes are measured and compared with that of the homogeneous combustion mode.The experimental results show that the combustion efficiency of the direct injection natural gas combustion is above 0.95 for all fuel supplying modes in the wide range of overall equivalence ratio.Fuel injection can operate within a wide range of equivalence ratio and has low unburned hydrocarbon emission (HC),low CO2 emission for the same power output,low NOx emission due to the mixture stratification compared with homogeneous combustion engine,especially in the range near the stoichiometric equivalence ratio where engine power output is needed.Consequently,the direct injection natural gas engine has the advantages of high thermal efficiency like diesel engine and low emission of premixed mixture combustion.

  12. Fluorouracil Injection (United States)

    ... of a doctor who is experienced in giving chemotherapy medications for cancer. Treatment with fluorouracil injection may cause serious side effects. ... this medication.If you experience a serious side effect, you or your doctor ... (FDA) MedWatch Adverse Event Reporting program online ( ...

  13. Lanreotide Injection (United States)

    Lanreotide injection is used to treat people with acromegaly (condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features; joint pain; and other symptoms) who have not successfully, or cannot be treated ...

  14. Paliperidone Injection (United States)

    ... the body slow movements or shuffling walk painful erection of the penis that lasts for hours cough, chills and/or other signs of infection Paliperidone injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a ...

  15. Ziprasidone Injection (United States)

    ... stiffness falling confusion sweating loss of consciousness painful erection of the penis that lasts for hours Ziprasidone injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a ...

  16. Risperidone Injection (United States)

    ... control slow movements or shuffling walk falling painful erection of the penis that lasts for hours Risperidone extended-release injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a ...

  17. Human herpes viruses in burn patients: A systematic review. (United States)

    Wurzer, Paul; Guillory, Ashley; Parvizi, Daryousch; Clayton, Robert P; Branski, Ludwik K; Kamolz, Lars-P; Finnerty, Celeste C; Herndon, David N; Lee, Jong O


    The contribution of human herpes viruses, including herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella zoster virus (VZV) to morbidity and mortality after burns remains controversial. This systematic review was undertaken to assess evidence of herpes virus-related morbidity and mortality in burns. PubMed, Ovid, and Web of Science were searched to identify studies of HSV, CMV, or VZV infections in burn patients. Exclusion criteria included: A level of evidence (LoE) of IV or V; nonhuman in vivo studies; and non-English articles. There was no limitation by publication date. Fifty articles were subjected to full-text analysis. Of these, 18 had LoE between I-III and were included in the final review (2 LoE I, 16 LoE II-III). Eight had a prospective study design, 9 had a retrospective study design, and 1 included both. No direct evidence linked CMV and HSV infection with increased morbidity and mortality in burns. Following burn, CMV reactivation was more common than a primary CMV infection. Active HSV infection impaired wound healing but was not directly correlated to mortality. Infections with VZV are rare after burns but when they occur, VZV infections were associated with severe complications including mortality. The therapeutic effect of antiviral agents administered after burns warrants investigation via prospective randomized controlled trials. Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

  18. Isolation of Bacillus Cereus from wounds and burns

    Directory of Open Access Journals (Sweden)

    Behzadiannejhad Gh


    Full Text Available The culture results of 203 cases with different wounds were studies; 150 of the latter were burn cases (mainly second and third degree burns, and 53 were of other types (surgical, traumatic, ect. Four subtypes of Bacillus cereus were isolated upon culture, and the different toxins produced in DHT broth with 0.1% glucose were assessed. The lethal toxin was injected intravenously to Syrian rats, none of whom died. VPR factor was assessed in the 4 subtypes. Three subtypes produced VPR in significant amounts.

  19. Efficacy of glutathione mesotherapy in burns: an experimental study. (United States)

    Buz, A; Görgülü, T; Olgun, A; Kargi, E


    Thermal burns are the leading cause of trauma worldwide. Currently, no consensus on optimal treatment of deep partial-thickness (second-degree) burns has emerged, as reflected by the wide variability in available wound-care materials. The relative efficacies of products used for treatment of partial-thickness thermal burns remain unclear. Mesotherapy features intradermal administration of various agents, depending on burn location. In the present experimental study, we explored the efficacy of mesotherapy used to treat partial-thickness thermal burns in 50 male Wistar rats divided into five groups of equal number. No procedure was performed after infliction of thermal burns in control group (Group 1). Mesotherapy was applied with physiological saline in sham group (Group 2), glutathione, taurine, and L-carnitine were separately applied in Group 3, Group 4, and Group 5, respectively. Mesotherapeutic agents were injected intradermally into the reticular layer of the dermis using the point technique. The first course of mesotherapy was given within the first 2 h after infliction of thermal burns, and therapy was continued to day 10. On day 22, unhealed thermal burn areas were measured prior to sacrifice, and biopsies covering the total areas of burns were performed to allow of pathological evaluation. Group 3 (the glutathione group) showed the best extent of healing, followed by Group 4 (the taurine group) and Group 5 (the L-carnitine group). The healed thermal burn areas in these groups were significantly greater than those in the control and sham groups (P = 0.001). All of healing, acute and chronic inflammation, the amount of granulation tissue, the level of fibroblast maturation, the amount of collagen, the extent of re-epithelization and neovascularization, and ulcer depth were scored upon pathological examination of tissue cross-sections. The best outcomes were evident in the glutathione group, with statistical significance. Although wound healing in the L

  20. Effect of Corn Stalk Bio-Oil on Combustion and Emission Characteristics of Direct Injection Diesel Engine%玉米秸秆生物油对直喷式柴油机燃烧与排放的影响

    Institute of Scientific and Technical Information of China (English)

    韩旭东; 黄勇成; 易延洪; 黄松; 闻振江


    The experimental bio-oil was produced from corn stalk through fast pyrolysis process. In this paper, four emulsions with 5%, 10%, 15% and 20% by mass fraction of corn stalk bio-oil (CSB) in diesel fuel, represented by CSB5, CSB10, CSB15 and CSB20, respectively, were prepared by the ultrasonic emulsification method. Then, the combustion and emission characteristics of an unmodified direct injection diesel engine operating on the four emulsions were studied and compared with those of No. 0 diesel operation in order to provide the basis and theoretical guidance for the application of bio-oil in diesel engines. The results showed that, with the increase of CSB mass fraction in the emulsions, the ignition delay lengthens, both the heat released during the premixed combustion phase and the premixed combustion duration increase, while the total combustion duration shortens. With the increase of CSB mass fraction in the emulsions, the peak values of both premixed burning rate and pressure rise rate increase first and then decrease, while those of in-cylinder pressure and combustion temperature decrease. In addition, the fuel economy of CSB5 and CSB 10 is comparable to that of No. 0 diesel, while the fuel economy of CSB 15 and CSB20 is slightly poorer than that of No. 0 diesel. In comparison with No. 0 diesel, NOx emissions of all the emulsions are lower, while HC and CO emissions are higher. Furthermore, these trends are more remarkable with the increase of CSB fraction in the emulsions. Smoke emissions of the emulsions decrease first and then increase with the increase of CSB fraction in the emulsions. Meanwhile, smoke emissions of CSB5 and CSB 10 are lower while those of CSB 15 and CSB20 are slightly higher than those of No. 0 diesel.%采用超声波乳化法制备了玉米秸秆热解生物油质量分数分别为5%、10%、15%和20%的生物油/柴油乳化油,分别记为CSB5、CSB10、CSB15和CSB20,然后在一台未作改动的直喷式

  1. Making an Orthotopic Tumor Model of Hepatocellular Carcinoma for ICR Mice by Direct Injection%直接注射法制作ICR小鼠肝癌原位移植瘤模型

    Institute of Scientific and Technical Information of China (English)

    张建民; 施晓雷; 陶科; 潘军平; 吴亚夫


    目的:培养鼠肝癌H22细胞,直接注射法制作ICR小鼠肝癌原位移植瘤,为后续实验奠定基础.方法:鼠肝癌H22细胞体外培养,将调整好的对数生长期的肝癌细胞直接注射小鼠肝脏,2周后解剖观察,并进行组织HE染色.结果:所有实验小鼠均可见肿瘤生长,HE染色示肝细胞肝癌.结论:直接注射法制作ICR小鼠肝癌原位移植瘤模型简便易行,值得推广应用.%Objective: To cultivate H22 cell line and making an orthotopic tumor model of hepatocellular carcinoma on ICR mouse using direct injection method to lay the foundation for subsequent experiment. Methods: Cultivate H22 cell line in vitro and an orthotopic xenograft tumor model of hepatocellular carcinoma was created by injection of H22 cells in logarithmic growth phase directly into the liver parenchyma of ICR mice. Two weeks later, hepatocellular carcinoma specimens of animals were observed and stained with hematoxylin/eosin. Results: Tumor growth happened on all the experimental mice and was showed as hepatocellular carcinoma by hematoxylin-eosin staining. Conclusion: It is convenient of direct injection method on making an orthotopic tumor model of hepatocellular carcinoma and should be reported and used widely.

  2. Modélisation et simulation de la boucle des gaz dans un moteur diesel suralimenté à injection directe


    Sabeh, Zahi; Ragot, José; Maquin, Didier


    National audience; La complexité des moteurs diesel modernes contrôlés par l'électronique, avec un nombre croissant de capteurs et d'actionneurs, nécessite des systèmes de mesure et de diagnostic améliorés et automatisés à bord des véhicules utilisant ces moteurs. La surveillance appropriée et la détection précoce des défauts nécessite de disposer de modèles de bon fonctionnement des composants et, dans cette communication, on s'intéresse à la boucle des gaz d'un moteur diesel à injection dir...

  3. Improvement of combustion in a direct injection diesel engine by micro-hole nozzle; Micro hole nozzle wo mochiita chokusetsu funshashiki diesel kikan no nensho kaizen

    Energy Technology Data Exchange (ETDEWEB)

    Murata, M. [Keio University, Tokyo (Japan); Kobori, S. [Tokyo Institute of Technology, Tokyo (Japan); Iida, N. [Keio University, Tokyo (Japan). Faculty of Science and Technology


    In an attempt to promote the atomization of fuel spray and the mixing of fuel and air in diesel engines, a micro-hole nozzle which has orifices with a diameter smaller than 0.10mm was developed. In this study, the combustion tests were carried out using a single cylinder diesel engine equipped with a micro-hole nozzle and a common rail type high-pressure fuel injection system. A comparison with the results of a conventional nozzle experiment showed that the peak of initial premixed combustion increased, but the peak of diffusion combustion decreased. As a result, when nozzle orifice diameter become small from {phi} 0.15 mm to {phi} 0.10 mm, the combustion was accompanied by smokeless with the same levels of NO{sub x} emission and fuel economy. And results of a comparison the toroidal type chamber with the shallow dish type chamber revealed that the optimization of combustion chamber is necessary for the increase of the injection stage with increasing of the number of nozzle orifice. If an orifice diameter becomes {phi} 0.06 mm, the diffusion combustion can not be observed and the combustion is formed of only premixed combustion. The combustion in the case of {phi} 0.06 mm was accompanied with the drastic deterioration of fuel economy, smoke and HC with all over load. But the micro-hole nozzle has a potential for the formation of the lean and homogeneous premixed mixture until the fuel-air mixture ignites. (author)

  4. Direct large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry determination of artificial sweeteners sucralose and acesulfame in well water. (United States)

    Wu, Minghuo; Qian, Yichao; Boyd, Jessica M; Hrudey, Steve E; Le, X Chris; Li, Xing-Fang


    Acesulfame (ACE) and sucralose (SUC) have become recognized as ideal domestic wastewater contamination indicators. Liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) analysis is commonly used; however, the sensitivity of SUC is more than two orders of magnitude lower than that of ACE, limiting the routine monitoring of SUC. To address this issue, we examined the ESI behavior of both ACE and SUC under various conditions. ACE is ionic in aqueous solution and efficiently produces simple [M-H](-) ions, but SUC produces multiple adduct ions, limiting its sensitivity. The formic acid (FA) adducts of SUC [M+HCOO](-) are sensitively and reproducibly generated under the LC-MS conditions. When [M+HCOO](-) is used as the precursor ion for SUC detection, the sensitivity increases approximately 20-fold compared to when [M-H](-) is the precursor ion. To further improve the limit of detection (LOD), we integrated the large volume injection approach (500μL injection) with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), which reduced the method detection limit (MDL) to 0.2ng/L for ACE and 5ng/L for SUC. To demonstrate the applicability of this method, we analyzed 100 well water samples collected in Alberta. ACE was detected in 24 wells at concentrations of 1-1534ng/L and SUC in 8 wells at concentrations of 65-541ng/L. These results suggest that wastewater is the most likely source of ACE and SUC impacts in these wells, suggesting the need for monitoring the quality of domestic well water.

  5. The hair color-highlighting burn: a unique burn injury. (United States)

    Peters, W


    A unique, preventable, 2.8 x 3.7-cm, full-thickness scalp burn resulted after a woman underwent a professional color-highlighting procedure at a hair salon. The burn appeared to result from scalp contact with aluminum foil that had been overheated by a hair dryer during the procedure. The wound required debridement and skin grafting and 3 subsequent serial excisions to eliminate the resulting area of burn scar alopecia. The preventive aspects of this injury are discussed.

  6. Mixture formation of direct gasoline injection engine. In cylinder gas sampling using fast response ionization detector; Tonai funsha gasoline engine no kongoki keisei. Kosoku FID ni yoru tonai gas sampling

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, H.; Marubara, M.; Ota, N.; Kudo, H.; Yamamoto, H. [Mazda Motor Corp., Hiroshima (Japan)


    Local mixture concentration near the spark plug of a direct gasoline injection engine was observed by a fast flame ionization detector. To ensure combustion stability and good fuel economy in DISC operation, the swirl ratio and the piston configuration were optimized. Swirl is needed to retain well-vaporized and stable mixture near the spark plug especially in light load. And adequate volume in piston cavity is required for trapping curved fuel spray in it. With these specifications, the fuel economy improvement of 13 to 30 % was realized. 2 refs., 13 figs., 1 tab.

  7. Probing thermonuclear burning on accreting neutron stars


    Keek, L.


    Neutron stars are the most compact stars that can be directly observed, which makes them ideal laboratories to study physics at extreme densities. Neutron stars in low-mass X-ray binaries accrete hydrogen and helium from a lower-mass companion star through Roche lobe overflow. This matter undergoes thermonuclear burning in the neutron star envelope, creating carbon and heavier elements. The fusion process may proceed in an unstable manner, resulting in a thermonuclear runaway. Within one seco...

  8. Examination of the Entry to Burn and Burn Control for the ITER 15 MA Baseline and Other Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Kesse, Charles E. [PPPL; Kim, S-H. [ITER; Koechl, F. [EURATOM-OAW/ATI


    The entry to burn and flattop burn control in ITER will be a critical need from the first DT experiments. Simulations are used to address time-dependent behavior under a range of possible conditions that include injected power level, impurity content (W, Ar, Be), density evolution, H-mode regimes, controlled parameter (Wth, Pnet, Pfusion), and actuator (Paux, fueling, fAr), with a range of transport models. A number of physics issues at the L-H transition require better understanding to project to ITER, however, simulations indicate viable control with sufficient auxiliary power (up to 73 MW), while lower powers become marginal (as low as 43 MW).

  9. An Experimental Study on the Fast Light Off of Catalytic Converter in a Gasoline Direct Injection Engine%直喷汽油机催化器快速起燃的试验研究

    Institute of Scientific and Technical Information of China (English)

    于秀敏; 董伟; 嵇全喜


    针对EA888直喷汽油机建立了试验台架及试验测控系统,通过试验研究了过量空气系数和两次喷射比例对催化器起燃特性的影响规律.试验结果表明,采用微稀的混合气有利于催化器的快速起燃,采用两次喷射有助于推迟点火,提高排气温度,缩短催化器起燃时间.%A test bench and its control system are established for EA888 direct injection gasoline engine, and an experimental study is conducted on the rule of the effects of excess air coefficient and the fuel proportion ratio in two-stage fuel injection on the light-off characteristics of catalytic converter. The results show that a slight-lean mixture is conducive to the rapid light off of catalytic converter, and two-stage injection helps delay ignition, raise exhaust temperature and shorten the light-off time of catalyst.

  10. Developments in Spray Modeling in Diesel and Direct-Injection Gasoline Engines Progrès de la modélisation des sprays dans les moteurs Diesel et à essence

    Directory of Open Access Journals (Sweden)

    Kong S. C.


    Full Text Available In direct-injection engines, the fuel spray characteristics influence the combustion efficiency and exhaust emissions. The performance of available spray models for predicting liquid and vapor fuel distributions, and their influence on combustion is reviewed for both diesel and gasoline direct injection engines. A phenomenological nozzle flow model is described for simulating the effects of diesel injector nozzle internal geometry on the fuel injection and spray processes. The flow model provides initial conditions for the liquid jet breakup model that considers wave instabilities due to Kelvin-Helmholtz (KH and Rayleigh-Taylor (RT mechanisms. A linearized instability analysis has also been extended to consider the breakup of liquid sheets for modeling pressure-swirl gasoline injectors. Diesel engine predictions have been compared with extensive data from in-cylinder laser diagnostics carried out in optically accessible heavy-duty, DI Diesel engines over a wide range of operating conditions. The results show that the nozzle flow model used in combination with the KH and RT models gives realistic spray predictions. In particular, the limited liquid fuel penetration length observed experimentally and the flame shape details are captured accurately. The liquid sheet breakup model has also been compared favorably with experimental spray penetration and drop size data for gasoline hollow-cone sprays. This model is currently being applied to study stratified charge combustion in GDI engines. Dans les moteurs à injection directe, les caractéristiques du spray de carburant influent directement sur le rendement et les émissions. Les performances des modèles de spray existants et leur influence sur la combustion pour les moteurs Diesel et essence à injection directe sont analysées. Un modèle phénoménologique d'écoulement dans les injecteurs indiquant les effets de la géométrie sur les processus d'injection est présenté. Ce modèle donne les

  11. Assessment of burn depth and burn wound healing potential. (United States)

    Monstrey, Stan; Hoeksema, Henk; Verbelen, Jos; Pirayesh, Ali; Blondeel, Phillip


    The depth of a burn wound and/or its healing potential are the most important determinants of the therapeutic management and of the residual morbidity or scarring. Traditionally, burn surgeons divide burns into superficial which heal by rapid re-epithelialization with minimal scarring and deep burns requiring surgical therapy. Clinical assessment remains the most frequent technique to measure the depth of a burn wound although this has been shown to be accurate in only 60-75% of the cases, even when carried out by an experienced burn surgeon. In this article we review all current modalities useful to provide an objective assessment of the burn wound depth, from simple clinical evaluation to biopsy and histology and to various perfusion measurement techniques such as thermography, vital dyes, video angiography, video microscopy, and laser Doppler techniques. The different needs according to the different diagnostic situations are considered. It is concluded that for the initial emergency assessment, the use of telemetry and simple burn photographs are the best option, that for research purposes a wide range of different techniques can be used but that, most importantly, for the actual treatment decisions, laser Doppler imaging is the only technique that has been shown to accurately predict wound outcome with a large weight of evidence. Moreover this technique has been approved for burn depth assessment by regulatory bodies including the FDA.

  12. Does fire severity influence shrub resprouting after spring prescribed burning? (United States)

    Fernández, Cristina; Vega, José A.; Fonturbel, Teresa


    Prescribed burning is commonly used to reduce the risk of severe wildfire. However, further information about the associated environmental effects is required to help forest managers select the most appropriate treatment. To address this question, we evaluated if fire severity during spring prescribed burning significantly affects the resprouting ability of two common shrub species in shrubland under a Mediterranean climate in NW Spain. Fire behaviour and temperatures were recorded in tagged individuals of Erica australis and Pterospartum tridentatum during prescribed burning. The number and length of resprouted shoots were measured three times (6, 12 and 18 months) after the prescribed burning. The influence of a series of fire severity indicators on some plant resprouting vigour parameters was tested by canonical correlation analysis. Six months and one year after prescribed burning, soil burn severity (measured by the absolute reduction in depth of the organic soil layer, maximum temperatures in the organic soil layer and the mineral soil surface during burning and the post-fire depth of the organic soil layer) reduced the resprouting vigour of E. australis and P. tridentatum. In contrast, direct measurements of fire effects on plants (minimum branch diameter, duration of temperatures above 300 °C in the shrub crown and fireline intensity) did not affect the post-fire plant vigour. Soil burn severity during spring prescribed burning significantly affected the short-term resprouting vigour in a mixed heathland in Galicia. The lack of effects eighteen months after prescribed burning indicates the high resilience of these species and illustrates the need to conciliate fire prevention and conservation goals.

  13. Supersonic Jet Noise Reduction Using Flapping Injection and Pulsed Injection (United States)

    Hafsteinsson, Haukur; Eriksson, Lars-Erik; Cuppoletti, Daniel; Gutmark, Ephraim; Department of Applied Mechanics, Chalmers University of Technology Team; Department of Aerospace Engineering, University of Cincinatti Team; Swedish Defence Material Administration, Sweden Team


    Aircraft are in general noisy and there is a high demand for reducing their noise levels. The jet exhaust is in most cases the main noise source of the aircraft, especially for low bypass ratio jet engines. Fluidic injection affecting the shear layer close to the nozzle exit is a promising noise reduction technique as it can be turned of while not needed and thus the negative effect on the engine performance will be minimized. In the presented work, LES is used to compare steady-state mass flow injection with steady-state mass flow flapping jet injection. The work is a direct continuation of a previous LES study on pulsed injection which showed that the pulsed injection induced pressure pulses in the jet which caused increased tonal noise in the downstream directions. The injection system considered in the presented work consists of eight evenly distributed injectors at the nozzle exit plane with a 90° injection angle relative to the flow direction. Flapping jet injection is believed to minimize the creation of these pressure pulses since it provides steady-state mass flow. This work is funded by Swedish Defense Material Administration (FMV).

  14. Ghrelin improves burn-induced delayed gastrointestinal transit in rats. (United States)

    Sallam, H S; Oliveira, H M; Gan, H T; Herndon, D N; Chen, J D Z


    Delayed gastrointestinal transit is common in patients with severe burn. Ghrelin is a potent prokinetic peptide. We aimed at testing the effect of ghrelin on burn-induced delayed gastrointestinal transit in rats. Gastric emptying (GE), intestinal transit (IT), and colonic transit (CT) studies were performed in male Sprague-Dawley rats. Rats were randomized into two main groups as follows: sham injury and ghrelin-treated burn injury with doses of 0, 2, 5, and 10 nmol/rat ip 6 h after burn. Sham/burn injury was induced under anesthesia. Rats received a phenol red meal 20 min following ghrelin injection. Based on the most effective ghrelin dose, 1 mg/kg sc atropine was given 30 min before the ghrelin in one group of rats for each study. The rats in each group were killed 30-90 min later; their stomachs, intestines, and colons were harvested immediately, and the amount of phenol red recovered was measured. Percentage of gastric emptying (GE%) and geometric center for IT and CT were calculated. We found 1) severe cutaneous burn injury significantly delayed GE, IT, and CT compared with sham injury (P CT; 3) the most effective dose of ghrelin was 2 nmol/rat; and 4) atropine blocked the prokinetic effects of ghrelin on GE% and IT. In conclusion, ghrelin normalizes burn-induced delayed GE and IT but has no effect on CT in rats. The prokinetic effects of ghrelin are exerted via the cholinergic pathway. Ghrelin may have a therapeutic potential for burn patients with delayed upper gastrointestinal transit.

  15. Subcutaneous (SQ) injections (United States)

    SQ injections; Sub-Q injections; Diabetes subcutaneous injection; Insulin subcutaneous injection ... NIH. Giving a subcutaneous injection . Rockville, MD. National ... of Health and Human Services NIH publications; 2015. Available ...

  16. Curcumin: a novel therapeutic for burn pain and wound healing (United States)


    for controlling pain and wound healing. Several reports clearly demonstrate that cur- cumin can directly act on nociceptive neurons and inhibit...bioavailability 5. Curcumin delivery vehicles 6. Conclusion 7. Expert opinion Review Curcumin: a novel therapeutic for burn pain and wound healing Bopaiah...Surgical Research, Battlefield Pain Management Research Task Area, Fort Sam Houston, TX, USA Introduction: Managing burn injury-associated pain and wounds

  17. [The organization of burn care]. (United States)

    Latarjet, Jacques


    In 2002, the organisation of burn care is confronted to a great deficiency in burn epidemiological datas. The main mechanisms of hospitalized burns are somehow wellknown in industrialized countries: about 60% scalds and 30% flame burns; as well as the place of occurrence (60% at home, and 20% at work), and the risk groups (3 times more important for the age group 0-4 years old). The incidence of burns needing medical care (all levels) (250/100,000 inh/yr) or hospitalization (15-20/100,000 inh/yr) is much more uncertain. The statistics of Diagnosis Related Groups (DRG), for hospitalized patients will allow in France very shortly to know more about the most rational ways of dispatching and treating them. They already show that only 30% of hospitalized burned patients are treated in specialized facilities.

  18. [Epidemiology of burns in France]. (United States)

    Latarjet, Jacques; Ravat, François


    As with most traumas, the epidemiology of the "burn" health-event has long been neglected by public health doctors and rarely considered by burns specialists. There were therefore few verified data and many approximations and preconceived ideas. The gathering of information recently undertaken in France enables the reliability of the data to be improved and the diagnostic and demographic elements relating to hospitalised patients with burns to be established.

  19. Genital burns and vaginal delivery. (United States)

    Pant, R; Manandhar, V; Wittgenstein, F; Fortney, J A; Fukushima, C


    Obstetric complications may result from burn scarring in the genital area. Women in developing countries typically squat around cooking fires, and burns are common. This recent case in Nepal describes obstructed labor in a young woman whose genital area had extensive scarring from a cooking fire injury. Proper antenatal assessment by health care providers can reduce the risk to mothers and infants of the consequences of a birth canal damaged or obstructed by burn scarring.

  20. Curbing Inflammation in Burn Patients

    Directory of Open Access Journals (Sweden)

    Jayme A. Farina


    Full Text Available Patients who suffer from severe burns develop metabolic imbalances and systemic inflammatory response syndrome (SIRS which can result in multiple organ failure and death. Research aimed at reducing the inflammatory process has yielded new insight into burn injury therapies. In this review, we discuss strategies used to curb inflammation in burn injuries and note that further studies with high quality evidence are necessary.

  1. Nutrition Support in Burn Patients

    Directory of Open Access Journals (Sweden)

    Cem Aydoğan


    Full Text Available Severe burn trauma causes serious metabolic derangements. Increased metabolic rate which is apart of a pathophysiologic characteristic of burn trauma results in protein-energy malnutrition. This situation causes impaired wound healing, muscle and fat tissue’s breakdown, growth retardation in children and infections. Nutrition support is vital in the treatment strategies of burn victims to prevent high mortal and disabling complications in this devastating trauma. Our aim in this study is to review management of nutrition in burn victims. (Journal of the Turkish Society Intensive Care 2012; 10: 74-83

  2. A primer on burn resuscitation

    Directory of Open Access Journals (Sweden)

    Bacomo Ferdinand


    Full Text Available Since the early 1900s, the scope of burn resuscitation has evolved dramatically. Due to various advances in pre-hospital care and training, under-resuscitation of patients with severe burns is now relatively uncommon. Over-resuscitation, otherwise known as "fluid creep", has emerged as one of the most important problems during the initial phases of burn care over the past decade. To avoid the complications of over-resuscitation, careful hourly titration of fluid rates based on compilation of various clinical end points by a bedside provider is vital. The aim of this review is to provide a practical approach to the resuscitation of severely burned patients.

  3. Ice & Fire: the Burning Question

    DEFF Research Database (Denmark)

    van Gelderen, Laurens; Jomaas, Grunde


    With the Arctic opening up to new shipping routes and increased oil exploration and production due to climate change, the risk of an Arctic oil spill is increasing. Of the classic oil spill response methods (mechanical recovery, dispersants and in-situ burning), in-situ burning is considered...... to be particularly a suitable response method in the Arctic. In-situ burning aims to remove the oil from the marine environment by burning it from the water surface. A recent Ph.D. thesis from the Technical University of Denmark has provided some new insights with respect to the fire science behind this response...

  4. Marginally Stable Nuclear Burning (United States)

    Strohmayer, Tod E.; Altamirano, D.


    Thermonuclear X-ray bursts result from unstable nuclear burning of the material accreted on neutron stars in some low mass X-ray binaries (LMXBs). Theory predicts that close to the boundary of stability oscillatory burning can occur. This marginally stable regime has so far been identified in only a small number of sources. We present Rossi X-ray Timing Explorer (RXTE) observations of the bursting, high-inclination LMXB 4U 1323-619 that reveal for the first time in this source the signature of marginally stable burning. The source was observed during two successive RXTE orbits for approximately 5 ksec beginning at 10:14:01 UTC on March 28, 2011. Significant mHz quasi-periodic oscillations (QPO) at a frequency of 8.1 mHz are detected for approximately 1600 s from the beginning of the observation until the occurrence of a thermonuclear X-ray burst at 10:42:22 UTC. The mHz oscillations are not detected following the X-ray burst. The average fractional rms amplitude of the mHz QPOs is 6.4% (3 - 20 keV), and the amplitude increases to about 8% below 10 keV.This phenomenology is strikingly similar to that seen in the LMXB 4U 1636-53. Indeed, the frequency of the mHz QPOs in 4U 1323-619 prior to the X-ray burst is very similar to the transition frequency between mHz QPO and bursts found in 4U 1636-53 by Altamirano et al. (2008). These results strongly suggest that the observed QPOs in 4U 1323-619 are, like those in 4U 1636-53, due to marginally stable nuclear burning. We also explore the dependence of the energy spectrum on the oscillation phase, and we place the present observations within the context of the spectral evolution of the accretion-powered flux from the source.

  5. Exercise following burn injury. (United States)

    de Lateur, Barbara J; Shore, Wendy S


    Fatigue is a major barrier to recovery for burned individuals. Studies indicate that a slow return to normal or near-normal muscle strength is the natural course of recovery. With no special interventions, other than the "usual care" tailored to the needs of the individual, postburn patients will make gradual improvement in strength and aerobic capacity. Using the principle of initial condition (the worse the initial condition, the greater the response to exercise intervention) the authors outline an augmented exercise program that should result in a robust improvement in aerobic capacity.

  6. In vivo imaging of intracellular Ca2+ after muscle contractions and direct Ca2+ injection in rat skeletal muscle in diabetes. (United States)

    Eshima, Hiroaki; Tanaka, Yoshinori; Sonobe, Takashi; Inagaki, Tadakatsu; Nakajima, Toshiaki; Poole, David C; Kano, Yutaka


    The effects of muscle contractions on the profile of postcontraction resting intracellular Ca2+ ([Ca2+]i) accumulation in Type 1 diabetes are unclear. We tested the hypothesis that, following repeated bouts of muscle contractions, the rise in resting [Ca2+]i evident in healthy rats would be increased in diabetic rats and that these changes would be associated with a decreased cytoplasmic Ca2+ -buffering capacity. Adult male Wistar rats were divided randomly into diabetic (DIA; streptozotocin, ip) and healthy control (CONT) groups. Four weeks later, animals were anesthetized and spinotrapezius muscle contractions (10 sets of 50 contractions) were elicited by electrical stimulation (100 Hz). Ca2+ imaging was achieved using Fura-2 AM in the spinotrapezius muscle in vivo (i.e., circulation intact). The ratio (340/380 nm) was determined from fluorescence images following each set of contractions for estimation of [Ca2+]i. Also, muscle Ca2+ buffering was studied in individual myocytes microinjected with 2 mM Ca2+ solution. After muscle contractions, resting [Ca2+]i in DIA increased earlier and more rapidly than in CONT (P contractions. Markedly different responses to Ca2+ injection in DIA vs. CONT suggest fundamentally deranged Ca2+ handling.

  7. Direct charge carrier injection into Ga2O3 thin films using an In2O3 cathode buffer layer: their optical, electrical and surface state properties (United States)

    Cui, W.; Zhao, X. L.; An, Y. H.; Guo, D. Y.; Qing, X. Y.; Wu, Z. P.; Li, P. G.; Li, L. H.; Cui, C.; Tang, W. H.


    Conductive Ga2O3 thin films with an In2O3 buffer layer have been prepared on c-plane sapphire substrates using a laser molecular beam epitaxy technique. The effects of the In2O3 buffer layer on the structure and optical, electrical and surface state properties of the Ga2O3 films have been studied. The change in conductivity of the thin films is attributed to different thicknesses of the In2O3 buffer layer, which determine the concentration of charge carriers injected into the upper Ga2O3 layer from the interface of the bilayer thin films. In addition, the increase in flat band voltage shift and capacitance values as the In2O3 buffer layer thickens are attributed to the increase in surface state density, which also contributes to the rapid shrinkage of the optical band gap of the Ga2O3. With transparency to visible light, high n-type conduction and the ability to tune the optical band gap and surface state density, we propose that Ga2O3/In2O3 bilayer thin film is an ideal n-type semiconductor for fabrication of transparent power devices, solar cell electrodes and gas sensors.

  8. Direct Injection of CRISPR/Cas9-Related mRNA into Cytoplasm of Parthenogenetically Activated Porcine Oocytes Causes Frequent Mosaicism for Indel Mutations

    Directory of Open Access Journals (Sweden)

    Masahiro Sato


    Full Text Available Some reports demonstrated successful genome editing in pigs by one-step zygote microinjection of mRNA of CRISPR/Cas9-related components. Given the relatively long gestation periods and the high cost of housing, the establishment of a single blastocyst-based assay for rapid optimization of the above system is required. As a proof-of-concept, we attempted to disrupt a gene (GGTA1 encoding the α-1,3-galactosyltransferase that synthesizes the α-Gal epitope using parthenogenetically activated porcine oocytes. The lack of α-Gal epitope expression can be monitored by staining with fluorescently labeled isolectin BS-I-B4 (IB4, which binds specifically to the α-Gal epitope. When oocytes were injected with guide RNA specific to GGTA1 together with enhanced green fluorescent protein (EGFP and human Cas9 mRNAs, 65% (24/37 of the developing blastocysts exhibited green fluorescence, although almost all (96%, 23/24 showed a mosaic fluorescent pattern. Staining with IB4 revealed that the green fluorescent area often had a reduced binding activity to IB4. Of the 16 samples tested, six (five fluorescent and one non-fluorescent blastocysts had indel mutations, suggesting a correlation between EGFP expression and mutation induction. Furthermore, it is suggested that zygote microinjection of mRNAs might lead to the production of piglets with cells harboring various mutation types.

  9. Chromium, lead and cadmium in Danish milk products and cheese determined by Zeeman graphite furnace atomic absorption spectrometry after direct injection or pressurised ashing

    DEFF Research Database (Denmark)

    Larsen, Erik Huusfeldt; Rasmussen, L.


    -degrees-C and then further ashed at 1 100-degrees-C with argon as the purge gas. Zeeman background correction was used in the atomisation step at 2 300-degrees-C. The detection limit was 0.7 ng/g. Direct detection of chromium in milk, using only argon as purge gas, was inferior. Non-homogeneous and solid...

  10. Oral Rehydration Therapy in Burn Patients (United States)


    Burn Any Degree Involving 20-29 Percent of Body Surface; Burn Any Degree Involving 30-39 Percent of Body Surface; Burn Any Degree Involving 40-49 Percent of Body Surface; Burn Any Degree Involving 50-59 Percent of Body Surface; Burn Any Degree Involving 60-65 Percent of Body Surface

  11. How to manage burns in primary care.


    Waitzman, A. A.; Neligan, P C


    Burns are common injuries; more than 200,000 occur in Canada annually. Nearly all burn injuries can be managed on on outpatient basis. Appropriate treatment depends on burn depth, extent, and location. Special types of burns, such as chemical, tar, and electrical injuries, need specific management strategies. Prevention through education is important to reduce the incidence of burns.

  12. Combination of Radiation and Burn Injury Alters FDG Uptake in Mice (United States)

    Carter, Edward A.; Winter, David; Tolman, Crystal; Paul, Kasie; Hamrahi, Victoria; Tompkins, Ronald; Fischman, Alan J.


    Radiation exposure and burn injury have both been shown to alter glucose utilization in vivo. The present study was designed to study the effect of burn injury combined with radiation exposure, on glucose metabolism in mice using [18F] Fluorodeoxyglucose (18FDG). Groups of male mice weighing approximately 30g were studied. Group 1 was irradiated with a 137Cs source (9 Gy). Group 2 received full thickness burn injury on 25% total body surface area followed by resuscitated with saline (2mL, IP). Group 3 received radiation followed 10 minutes later by burn injury. Group 4 were sham treated controls. After treatment, the mice were fasted for 23 hours and then injected (IV) with 50 µCi of 18FDG. One hour post injection, the mice were sacrificed and biodistribution was measured. Positive blood cultures were observed in all groups of animals compared to the shams. Increased mortality was observed after 6 days in the burn plus radiated group as compared to the other groups. Radiation and burn treatments separately or in combination produced major changes in 18FDG uptake by many tissues. In the heart, brown adipose tissue (BAT) and spleen, radiation plus burn produced a much greater increase (p<0.0001) in 18FDG accumulation than either treatment separately. All three treatments produced moderate decreases in 18FDG accumulation (p<0.01) in the brain and gonads. Burn injury, but not irradiation, increased 18FDG accumulation in skeletal muscle; however the combination of burn plus radiation decreased 18FDG accumulation in skeletal muscle. This model may be useful for understanding the effects of burns + irradiation injury on glucose metabolism and in developing treatments for victims of injuries produced by the combination of burn plus irradiation. PMID:23143615

  13. The Potential Impact of a Hepatitis C Vaccine for People Who Inject Drugs: Is a Vaccine Needed in the Age of Direct-Acting Antivirals?

    Directory of Open Access Journals (Sweden)

    Jack Stone

    Full Text Available The advent of highly effective hepatitis C (HCV treatments has questioned the need for a vaccine to control HCV amongst people who inject drugs (PWID. However, high treatment costs and ongoing reinfection risk suggest it could still play a role. We compared the impact of HCV vaccination amongst PWID against providing HCV treatment.Dynamic HCV vaccination and treatment models among PWID were used to determine the vaccination and treatment rates required to reduce chronic HCV prevalence or incidence in the UK over 20 or 40 years. Projections considered a low (50% protection for 5 years, moderate (70% protection for 10 years or high (90% protection for 20 years efficacy vaccine. Sensitivities to various parameters were examined.To halve chronic HCV prevalence over 40 years, the low, moderate and high efficacy vaccines required annual vaccination rates (coverage after 20 years of 162 (72%, 77 (56% and 44 (38% per 1000 PWID, respectively. These vaccination rates were 16, 7.6 and 4.4 times greater than corresponding treatment rates. To halve prevalence over 20 years nearly doubled these vaccination rates (moderate and high efficacy vaccines only and the vaccination-to-treatment ratio increased by 20%. For all scenarios considered, required annual vaccination rates and vaccination-to-treatment ratios were at least a third lower to reduce incidence than prevalence. Baseline HCV prevalence had little effect on the vaccine's impact on prevalence or incidence, but substantially affected the vaccination-to-treatment ratios. Behavioural risk heterogeneity only had an effect if we assumed no transitions between high and low risk states and vaccinations were targeted or if PWID were high risk for their first year.Achievable coverage levels of a low efficacy prophylactic HCV vaccine could greatly reduce HCV transmission amongst PWID. Current high treatment costs ensure vaccination could still be an important intervention option.

  14. Bad advice; bad burn: a new problem in burn prevention. (United States)

    Deans, L; Slater, H; Goldfarb, I W


    Deep partial-thickness burns had been inflicted on the perineal area of an infant who was recently treated in our Burn Center. The burns were a result of advice to the patient's mother by a pediatrician. The doctor told her to use a hair dryer to prevent diaper rash. We surveyed pediatricians, well-baby clinics, and pediatric nurse practitioners in our area and found that approximately half of them advised the use of hair dryers to treat or prevent diaper rash. We tested four widely available hand-held hair dryers to determine potential for inflicting burn injury. All of the dryers are capable of delivering air heated to at least 53 degrees C after 2 minutes of use. We believe that warnings against the use of hair dryers for perineal hygiene should be included in burn prevention programs.

  15. A review of community management of paediatric burns. (United States)

    Cox, S G; Martinez, R; Glick, A; Numanoglu, A; Rode, H


    This study was a component of a broader review to evaluate burn care in South Africa. A prospective audit of 353 children with thermal injuries admitted to the Red Cross War Memorial Children's Hospital in Cape Town was performed during 2012/2013. The audit was based to assess the adherence of initial burn management to the provincial policy guidelines on the clinical management of the burn wound. The community management of each patient prior to admission to a burns centre was assessed for the following: basic demographics, emergency home management, wound cover, analgesia and transport to medical facilities. Their ages ranged from 1 month to 14 years. The average total body surface area [TBSA] was 15% [1-86%]. Most of the injuries were due to hot water accidents [78.5%] followed by flame burns (9%), direct contact and electricity burns. Two hundred and twenty five children [63%] received first aid measures at home, including cooling with water [166] ice [30] and a cooling agent. No cooling was instituted in 130 and 65% of the patient's wounds were cooled for 10 min or less. Eighty percent proceeded to the referral centre or burns unit without their wounds being covered; with only 19 patients having any medical type of dressing available at home. Two hundred and ninety five children [83.6%] received pain medication prior to admission at the burns unit. Of the 316 patients not directly attending the burns unit, 137 received i.v. fluids of which 95 had burns greater than 10% TBSA. None of the patients were in shock on admission and all i.v. lines were functioning. Forty-four children with burns greater than 10% did not receive i.v. fluids. The audit identified six factors that were inadequately addressed during the pre-admission period: first aid, cooling of the wound, early covering of the wound, resuscitation, pain management and transfer. If these could be readdressed, basic burn care would be substantially improved in the study area.

  16. 缸内直喷发动机快速起动首循环喷雾的数值模拟%Numerical Simulation of First Cycle Spray during Quick Start for In-cylinder Direct Injection Engine

    Institute of Scientific and Technical Information of China (English)

    韩立伟; 洪伟; 高定伟; 苏岩; 谢方喜


    基于某缸内直喷(GDI)发动机建立了三维模拟平台,并对喷雾模型进行了验证,进而对GDI发动机起动时第2缸的喷雾和混合气形成进行了数值模拟,分析了不同喷油策略下压缩上止点时混合气的空燃比分布和着火情况,并与试验结果进行了对比分析。研究结果表明:喷油时刻距离上止点相对较远或者在上止点附近时,混合气在压缩上止点倾向于自燃;若混合气偏稀,即使喷油时刻在距离上止点相对中间的位置时,混合气仍倾向于自燃。通过试验结合数值模拟的方法,分析并指出了第2缸在不同喷油策略下发生自燃、可以点燃和失火的区域。%The 3D simulation platform for a gasoline direct injection (GDI) engine was established ,the spray model was veri-fied ,and the spray and gas mixture formation of the second cylinder during engine start was simulated .The air-fuel ratio and ignition condition at top dead centre (TDC) under different injection strategies were analyzed and compared with experimental results .The results show that the compressed mixture is easy to ignite spontaneously when the injection timing is relatively far from or is close to TDC .The lean mixture is still inclined to ignite spontaneously even though the injection timing is relatively middle from TDC .Through the test and numerical simulation ,the areas of auto-ignition ,ignition and misfire for the second cylinder are finally determined under different injection strategies .

  17. Shabbes burn, a burn that occurs solely among Jewish orthodox children; due to accidental shower from overhead water heaters. (United States)

    Shoufani, A; Golan, J


    From January 1990 to January 2000, 35 children were treated in our department for Shabbes burn, a unique scald burn that occurred mainly among orthodox Jews during the Sabbath. A retrospective review was conducted to determine the extent of the problem, to understand the burn mechanism and to suggest a prevention program. A shower of hot water from the Sabbath heater is the cause of this burn. Among the Shabbes burn cases, 27 patients were female (77%) and 17 children (48%) were between 3 and 6 years old. It is suggested that this is a common burn that occurs among orthodox Jewish families and affects mainly females. Education programs using the media directed to the Jewish orthodox population have been conducted, this combined with redesigned of the heater, have reduced significantly the incidence of the burn as seen in our institute. However, even though efforts have been supported widely, there remains a need for educational and governmental regulations on a national level. This could aid orthodox Jews not only in Israel but globally, as well.

  18. Burn prevention mechanisms and outcomes: pitfalls, failures and successes. (United States)

    Atiyeh, Bishara S; Costagliola, Michel; Hayek, Shady N


    -risk groups. Depending on the population of the country, burns prevention could be a national programme. This can ensure sufficient funds are available and lead to proper coordination of district, regional, and tertiary care centres. It could also provide for compulsory reporting of all burn admissions to a central registry, and these data could be used to evaluate strategies and prevention programmes that should be directed at behavioural and environmental changes which can be easily adopted into lifestyle. Particularly in LMICs, the emphasis in burn prevention should be by advocating change from harmful cultural practices. This needs to be done with care and sensitivity. The present review is a summary of what has already been accomplished in terms of burn prevention highlighting some of the successes but above all the numerous pitfalls and failures. Recognizing these failures is the first step towards development of more effective burn prevention strategies particularly in LMICs in which burn injury remains endemic and associated with a high mortality rate. Burn prevention is not easy, but easy or not, we have no options; burns must be prevented.

  19. Biomass Burning Emissions from Fire Remote Sensing (United States)

    Ichoku, Charles


    Knowledge of the emission source strengths of different (particulate and gaseous) atmospheric constituents is one of the principal ingredients upon which the modeling and forecasting of their distribution and impacts depend. Biomass burning emissions are complex and difficult to quantify. However, satellite remote sensing is providing us tremendous opportunities to measure the fire radiative energy (FRE) release rate or power (FRP), which has a direct relationship with the rates of biomass consumption and emissions of major smoke constituents. In this presentation, we will show how the satellite measurement of FRP is facilitating the quantitative characterization of biomass burning and smoke emission rates, and the implications of this unique capability for improving our understanding of smoke impacts on air quality, weather, and climate. We will also discuss some of the challenges and uncertainties associated with satellite measurement of FRP and how they are being addressed.

  20. Biomass Burning Emissions from Fire Remote Sensing (United States)

    Ichoku, Charles


    Knowledge of the emission source strengths of different (particulate and gaseous) atmospheric constituents is one of the principal ingredients upon which the modeling and forecasting of their distribution and impacts depend. Biomass burning emissions are complex and difficult to quantify. However, satellite remote sensing is providing us tremendous opportunities to measure the fire radiative energy (FRE) release rate or power (FRP), which has a direct relationship with the rates of biomass consumption and emissions of major smoke constituents. In this presentation, we will show how the satellite measurement of FRP is facilitating the quantitative characterization of biomass burning and smoke emission rates, and the implications of this unique capability for improving our understanding of smoke impacts on air quality, weather, and climate. We will also discuss some of the challenges and uncertainties associated with satellite measurement of FRP and how they are being addressed.