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Sample records for bulk media assay

  1. Collapse of Incoherent Light Beams in Inertial Bulk Kerr Media

    DEFF Research Database (Denmark)

    Bang, Ole; Edmundson, Darran; Królikowski, Wieslaw

    1999-01-01

    We use the coherent density function theory to show that partially coherent beams are unstable and may collapse in inertial bulk Kerr media. The threshold power for collapse, and its dependence on the degree of coherence, is found analytically and checked-numerically. The internal dynamics of the...

  2. Soliton interaction in quadratic and cubic bulk media

    DEFF Research Database (Denmark)

    Johansen, Steffen Kjær; Bang, Ole

    2000-01-01

    Summary form only given. The understanding of how and to what extend the cubic nonlinearity affects beam propagation and spatial soliton formation in quadratic media is of vital importance in fundamental and applied nonlinear physics. We consider beam propagation under type-I SHG conditions...... in lossless bulk second order nonlinear optical materials with a nonvanishing third order nonlinearity. It is known that in pure second order systems a single soliton can never collapse whereas in systems with both nonlinearities and that stable single soliton propagation can only in some circumstances...

  3. Bulk media assay using backscattered Pu-Be neutrons

    CERN Document Server

    Csikai, J

    1999-01-01

    Spectral yields of elastically backscattered Pu-Be neutrons measured for graphite, water, polyethylene, liquid nitrogen, paraffin oil, SiO sub 2 , Al, Fe, and Pb slabs show a definite correlation with the energy dependence of the elastic scattering cross sections, sigma sub E sub L (E sub n). The C, N and O can be identified by the different structures in their sigma sub E sub L (E sub n) functions. The integrated spectral yields versus thickness exhibit saturation for each sample. The interrogated volume is limited by the presence of hydrogen in the sample. (author)

  4. Stability-Indicating HPLC Method for Posaconazole Bulk Assay

    OpenAIRE

    GARCIA, Cássia; COSTA, Gislaine; MENDEZ, Andreas

    2012-01-01

    A stability-indicating liquid chromatographic (LC) method was developed for the determination of posaconazole in bulk. Chromatographic separation was achieved using an isocratic elution in a reversed-phase system, with a mobile phase composed of methanol-water (75:25, v/v), at 1.0 mL min−1 flow. Samples were exposed to degradation under thermal, oxidative and acid/basic conditions, and no interference in the analysis was observed. System suitability was evaluated and results were satisfactory...

  5. Stability-indicating HPLC method for posaconazole bulk assay.

    Science.gov (United States)

    Garcia, Cássia V; Costa, Gislaine R; Mendez, Andreas S L

    2012-01-01

    A stability-indicating liquid chromatographic (LC) method was developed for the determination of posaconazole in bulk. Chromatographic separation was achieved using an isocratic elution in a reversed-phase system, with a mobile phase composed of methanol-water (75:25, v/v), at 1.0 mL min(-1) flow. Samples were exposed to degradation under thermal, oxidative and acid/basic conditions, and no interference in the analysis was observed. System suitability was evaluated and results were satisfactory (N = 4,900.00 tailing factor 1.04; RSD between injections = 0.65). The retention time of posaconazole was about 8.5 min and the method was validated within the concentration range 5-60 μg mL(-1) (r = 0.9996). Adequate results were obtained for repeatability (RSD % = 0.86-1.22), inter-day precision (RSD % = 1.21) and accuracy (98.13% mean recovery). Robustness was also determined to be satisfactory after evaluation. The proposed method was successfully applied to posaconazole bulk quantification, showing the method is useful for determination of the drug in routine analysis.

  6. Effect of extraction and assay media on analysis of airborne endotoxin

    NARCIS (Netherlands)

    Spaan, S.; Doekes, G.; Heederik, D.; Thorne, P.S.; Wouters, I.M.

    2008-01-01

    The measurement of airborne endotoxins is thus far not standardized. Earlier studies reported higher endotoxin yields when Tween 20 was added to the media used for filter extraction and in the Limulus amebocyte lysate (LAL) assay. This study compared four common media and assessed the effects of Twe

  7. Metal nanoparticles in condensed media: preparation and the bulk and surface structural dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Olenin, A Yu; Lisichkin, Georgii V [Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow (Russian Federation)

    2011-07-31

    The results of studies on the chemical synthesis and biosynthesis of metal nanoparticles in condensed media published after 2000 are analyzed and described systematically. The growth and transformations of the metallic core of nanoparticles as well as the composition and structure of the surface layer are considered and their effects on the nanoparticle size and shape are analyzed.

  8. Electromagnetic vacuum of complex media II: the Lamb, the bulk and the total vacuum energy

    CERN Document Server

    Donaire, M

    2011-01-01

    We study the physical content of the electromagnetic vacuum energy of a random medium made of atomic electric dipoles. We show that the Lamb energy is only a part of it and, consequently, that the Lamb-shift derives from a partial variation of the total vacuum energy. While at leading order in the molecular density the total vacuum energy is that of the optical bulk modes and equals the free-space Lamb energy, the Lamb, the bulk and the total vacuum energies differ at second order. In contrast to the bulk energy, local field factors (LFFs) are present both in the total vacuum energy and in the Lamb energy. They yield natural cutoffs for both spectra at a wavelength of the order of the typical correlation length. Functionally, the difference between the total vacuum and the Lamb energies is due to the presence of higher order LFFs in the former. Physically, the difference is attributed to a shift in the binding energies which structure the spatial configuration of the dipoles. For a Maxwell-Garnett dielectric,...

  9. Generation and Amplification of Tunable Multicolored Femtosecond Laser Pulses by Using Cascaded Four-Wave Mixing in Transparent Bulk Media

    Directory of Open Access Journals (Sweden)

    Jun Liu

    2010-04-01

    Full Text Available We have reviewed the generation and amplification of wavelength-tunable multicolored femtosecond laser pulses using cascaded four-wave mixing (CFWM in transparent bulk media, mainly concentrating on our recent work. Theoretical analysis and calculations based on the phase-matching condition could explain well the process semi-quantitatively. The experimental studies showed: (1 as many as fifteen spectral up-shifted and two spectral down-shifted sidebands were obtained simultaneously with spectral bandwidth broader than 1.8 octaves from near ultraviolet (360 nm to near infrared (1.2 μm; (2 the obtained sidebands were spatially separated well and had extremely high beam quality with M2 factor better than 1.1; (3 the wavelengths of the generated multicolor sidebands could be conveniently tuned by changing the crossing angle or simply replacing with different media; (4 as short as 15-fs negatively chirped or nearly transform limited 20-fs multicolored femtosecond pulses were obtained when one of the two input beams was negatively chirped and the other was positively chirped; (5 the pulse energy of the sideband can reach a μJ level with power stability better than 1% RMS; (6 broadband two-dimensional (2-D multicolored arrays with more than ten periodic columns and more than ten rows were generated in a sapphire plate; (7 the obtained sidebands could be simultaneously spectra broadened and power amplified in another bulk medium by using cross-phase modulation (XPM in conjunction with four-wave optical parametric amplification (FOPA. The characterization showed that this is interesting and the CFWM sidebands generated by this novel method have good enough qualities in terms of power stability, beam quality, and temporal features suited to various experiments such as ultrafast multicolor time-resolved spectroscopy and multicolor-excitation nonlinear microscopy.

  10. Novel mathematical models for cell-mediated cytotoxicity assays without applying enzyme kinetics but with combinations and probability: bystanders in bulk effector cells influence results of cell-mediated cytotoxicity assays.

    Science.gov (United States)

    Takayanagi, Toshiaki

    2011-07-01

    Cell-mediated cytotoxicity assays are widely implemented to evaluate cell-mediated cytotoxic activity, and some assays are analyzed using the analogy of enzyme kinetics. In the analogy, the effector cell is regarded as the enzyme, the target cell as the substrate, the effector cell-target cell conjugate as the enzyme-substrate complex and the dead target cell as the product. However, the assumptions analogous to those of enzyme kinetics are not always true in cell-mediated cytotoxicity assays, and the parameter analogous to the Michaelis-Menten constant is not constant but is dependent on the number of effector cells. Therefore I present novel mathematical models for cell-mediated cytotoxicity assays without applying enzyme kinetics. I instead use combinations and probability, because analysis of cell-mediated cytotoxicity assays by applying enzyme kinetics seems controversial. With my original models, I demonstrate simulations of the data in previously published papers. The results are exhibited in the same forms as the corresponding data. Comparing the simulation results with the published data, the results seem to agree well with the data. From simulations of cytotoxic assays with bulk effector cells, it appears that bystanders in bulk effector cells increase both the cytotoxic activity and the motility of effector cells.

  11. A Comparative Study of Newly Developed HPLC-DAD and UHPLC-UV Assays for the Determination of Posaconazole in Bulk Powder and Suspension Dosage Form

    Directory of Open Access Journals (Sweden)

    Dalia A. Hamdy

    2014-01-01

    Full Text Available Objective. To develop and compare HPLC-DAD and UHPLC-UV assays for the quantitation of posaconazole in bulk powder and suspension dosage form. Methods. Posaconazole linearity range was 5–50 μg/mL for both assays. For HPLC-DAD assay, samples were injected through Zorbax SB-C18 (4.6 × 250 mm, 5 μm column. The gradient elution composed of the mobile phase acetonitrile: 15 mM potassium dihydrogen orthophosphate (30 : 70 to 80 : 20, linear over 7 minutes pumped at 1.5 mL/min. For UHPLC-UV assay, samples were injected through Kinetex-C18 (2.1 × 50 mm, 1.3 μm column. The mobile phase composed of acetonitrile: 15 mM potassium dihydrogen orthophosphate (45 : 55 pumped isocratically at 0.4 mL/min. Detection wavelength was 262 nm in both methods. Results. The run time was 11 and 3 minutes for HPLC-DAD and UHPLC-UV assays, respectively. Both assays were linear (r2>0.999 with CV% and % error of the mean <3%. Limits of detection and quantitation were 0.82 and 2.73 μg/mL for HPLC-DAD and 1.04 and 3.16 μg/mL for UHPLC-UV, respectively. The methods quantitated PSZ in suspension dosage form with no observable interferences. Conclusions. Both assays were proven sensitive and selective according to ICH guidelines. UHPLC-UV assay exhibited some economic and chromatographic separation superiority.

  12. A Comparative Study of Newly Developed HPLC-DAD and UHPLC-UV Assays for the Determination of Posaconazole in Bulk Powder and Suspension Dosage Form.

    Science.gov (United States)

    Hamdy, Dalia A; Belal, Tarek S

    2014-01-01

    Objective. To develop and compare HPLC-DAD and UHPLC-UV assays for the quantitation of posaconazole in bulk powder and suspension dosage form. Methods. Posaconazole linearity range was 5-50 μg/mL for both assays. For HPLC-DAD assay, samples were injected through Zorbax SB-C18 (4.6 × 250 mm, 5 μm) column. The gradient elution composed of the mobile phase acetonitrile: 15 mM potassium dihydrogen orthophosphate (30 : 70 to 80 : 20, linear over 7 minutes) pumped at 1.5 mL/min. For UHPLC-UV assay, samples were injected through Kinetex-C18 (2.1 × 50 mm, 1.3 μm) column. The mobile phase composed of acetonitrile: 15 mM potassium dihydrogen orthophosphate (45 : 55) pumped isocratically at 0.4 mL/min. Detection wavelength was 262 nm in both methods. Results. The run time was 11 and 3 minutes for HPLC-DAD and UHPLC-UV assays, respectively. Both assays were linear (r (2) > 0.999) with CV% and % error of the mean DAD and 1.04 and 3.16 μg/mL for UHPLC-UV, respectively. The methods quantitated PSZ in suspension dosage form with no observable interferences. Conclusions. Both assays were proven sensitive and selective according to ICH guidelines. UHPLC-UV assay exhibited some economic and chromatographic separation superiority.

  13. An Approach for Assessing the Signature Quality of Various Chemical Assays when Predicting the Culture Media Used to Grow Microorganisms

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, Aimee E.; Sego, Landon H.; Webb-Robertson, Bobbie-Jo M.; Kreuzer, Helen W.; Anderson, Richard M.; Unwin, Stephen D.; Weimar, Mark R.; Tardiff, Mark F.; Corley, Courtney D.

    2013-02-01

    We demonstrate an approach for assessing the quality of a signature system designed to predict the culture medium used to grow a microorganism. The system was comprised of four chemical assays designed to identify various ingredients that could be used to produce the culture medium. The analytical measurements resulting from any combination of these four assays can be used in a Bayesian network to predict the probabilities that the microorganism was grown using one of eleven culture media. We evaluated combinations of the signature system by removing one or more of the assays from the Bayes network. We measured and compared the quality of the various Bayes nets in terms of fidelity, cost, risk, and utility, a method we refer to as Signature Quality Metrics

  14. Development of a Highly Sensitive Cell-Based Assay for Detecting Botulinum Neurotoxin Type A through Neural Culture Media Optimization.

    Science.gov (United States)

    Hong, Won S; Pezzi, Hannah M; Schuster, Andrea R; Berry, Scott M; Sung, Kyung E; Beebe, David J

    2016-01-01

    Botulinum neurotoxin (BoNT) is the most lethal naturally produced neurotoxin. Due to the extreme toxicity, BoNTs are implicated in bioterrorism, while the specific mechanism of action and long-lasting effect was found to be medically applicable in treating various neurological disorders. Therefore, for both public and patient safety, a highly sensitive, physiologic, and specific assay is needed. In this paper, we show a method for achieving a highly sensitive cell-based assay for BoNT/A detection using the motor neuron-like continuous cell line NG108-15. To achieve high sensitivity, we performed a media optimization study evaluating three commercially available neural supplements in combination with retinoic acid, purmorphamine, transforming growth factor β1 (TGFβ1), and ganglioside GT1b. We found nonlinear combinatorial effects on BoNT/A detection sensitivity, achieving an EC50 of 7.4 U ± 1.5 SD (or ~7.9 pM). The achieved detection sensitivity is comparable to that of assays that used primary and stem cell-derived neurons as well as the mouse lethality assay.

  15. Milk adulteration: Detection of bovine milk in bulk goat milk produced by smallholders in northeastern Brazil by a duplex PCR assay.

    Science.gov (United States)

    Rodrigues, N P A; Givisiez, P E N; Queiroga, R C R E; Azevedo, P S; Gebreyes, W A; Oliveira, C J B

    2012-05-01

    The aim of this study was to investigate the adulteration of goat milk produced by smallholders in semiarid northeastern Brazil with bovine milk as an adulterant. The study was requested by the association of smallholder producers in the region to investigate and to inhibit adulteration practices as a need to ensure the quality and safety of goat milk. A duplex PCR assay has been developed and standardized. Further validation was performed in 160 fresh bulk goat milk samples. The detection limit of the duplex PCR was 0.5% bovine milk in goat milk and the results indicated that 41.2% of the goat milk presented to market was positive for bovine milk. Making the test available to the association of producers, together with extension activities, have been applied to reduce adulteration in goat milk sold to small-scale dairy plants and to ensure the species origin for goat milk in the state of Paraíba.

  16. Evaluation of three real-time PCR assays for differential identification of Mycobacterium tuberculosis complex and nontuberculous mycobacteria species in liquid culture media.

    Science.gov (United States)

    Jung, Yu Jung; Kim, Ji-Youn; Song, Dong Joon; Koh, Won-Jung; Huh, Hee Jae; Ki, Chang-Seok; Lee, Nam Yong

    2016-06-01

    We evaluated the analytical performance of M. tuberculosis complex (MTBC)/nontuberculous mycobacteria (NTM) PCR assays for differential identification of MTBC and NTM using culture-positive liquid media. Eighty-five type strains and 100 consecutive mycobacterial liquid media cultures (MGIT 960 system) were analyzed by a conventional PCR assay (MTB-ID(®) V3) and three real-time PCR assays (AdvanSure™ TB/NTM real-time PCR, AdvanSure; GENEDIA(®) MTB/NTM Detection Kit, Genedia; Real-Q MTB & NTM kit, Real-Q). The accuracy rates for reference strains were 89.4%, 100%, 98.8%, and 98.8% for the MTB-ID V3, AdvanSure, Genedia, and Real-Q assays, respectively. Cross-reactivity in the MTB-ID V3 assay was mainly attributable to non-mycobacterium Corynebacterineae species. The diagnostic performance was determined using clinical isolates grown in liquid media, and the overall sensitivities for all PCR assays were higher than 95%. In conclusion, the three real-time PCR assays showed better performance in discriminating mycobacterium species and non-mycobacterium Corynebacterineae species than the conventional PCR assay.

  17. Ultrasensitive detection in optically dense physiological media: applications to fast reliable biological assays

    Science.gov (United States)

    Matveeva, Evgenia G.; Gryczynski, Ignacy; Berndt, Klaus W.; Lakowicz, Joseph R.; Goldys, Ewa; Gryczynski, Zygmunt

    2006-02-01

    We present a novel approach for performing fluorescence immunoassay in serum and whole blood using fluorescently labeled anti-rabbit IgG. This approach, which is based on Surface Plasmon-Coupled Emission (SPCE), provides increased sensitivity and substantial background reduction due to exclusive selection of the signal from the fluorophores located near a bio-affinity surface. Effective coupling range for SPCE is only couple of hundred nanometers from the metallic surface. Excited fluorophores outside the coupling layer do not contribute to SPCE, and their free-space emission is not transmitted through the opaque metallic film into the glass substrate. An antigen (rabbit IgG) was adsorbed to a slide covered with a thin silver metal layer, and the SPCE signal from the fluorophore-labeled anti-rabbit antibody, binding to the immobilized antigen, was detected. The effect of the sample matrix (buffer, human serum, or human whole blood) on the end-point immunoassay SPCE signal is discussed. The kinetics of binding could be monitored directly in whole blood or serum. The results showed that human serum and human whole blood attenuate the SPCE end-point signal and the immunoassay kinetic signal only approximately 2- and 3-fold, respectively (compared to buffer), resulting in signals that are easily detectable even in whole blood. The high optical absorption of the hemoglobin can be tolerated because only fluorophores within a couple of hundred nanometers from the metallic film contribute to SPCE. Both glass and plastic slides can be used for SPCE-based assays. We believe that SPCE has the potential of becoming a powerful approach for performing immunoassays based on surface-bound analytes or antibodies for many biomarkers directly in dense samples such as whole blood, without any need for washing steps.

  18. Toxic Effects of Titanium Dioxide Nanoparticles and Titanium Dioxide Bulk Salt in the Liver and Blood of Male Sprague-Dawley Rats Assessed by Different Assays.

    Science.gov (United States)

    Shakeel, Muhammad; Jabeen, Farhat; Qureshi, Naureen Aziz; Fakhr-E-Alam, Muhammad

    2016-10-01

    This study evaluated the toxic effects of titanium dioxide (TiO2) bulk salt as well as its nanoparticles (NPs) in anatase phase with mean crystallite size of 36.15 nm in male Sprague-Dawley rats by subcutaneous injections at four different dose levels of either control (0), 50, 100 or 150 mg/kg of body weight (BW) of rat for 28 days on alternate days. Animal mortality, haematology, micronucleus assay, liver histology and activities of liver tissue damage markers like, alkaline phosphate (ALP), alanine transaminase (ALT), aspartate transaminase (AST), as well as oxidative stress indicators like superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), reduced glutathione (GSH) and lipid peroxidation (LPO) were investigated. The study revealed significant differences (P < 0.05) among control and experimental groups in all the haematological parameters at the end of experiment. Significantly elevated levels (P < 0.05) of ALT, AST and ALP were found for the group treated with TiO2 NPs at the dose of 150 mg/kg of body weight as compared to control. TiO2 and TiO2 NPs caused dose-dependent genotoxicity in the blood cells of the treated rat as revealed by micronuclei test. The highest frequency of micronuclei was observed in rats treated with NPs at the dose of 150 mg/kg BW which was significantly different (P < 0.001) from all other experimental groups after 28 days of exposure. Similarly, all the treatments showed dose-dependent oxidative stress in the treated rats. However, the significantly high decline in the activities of CAT, SOD, and GST as well as elevation in malondialdehyde and GSH was observed in the group receiving NPs at the rate of 150 mg/kg BW. TiO2 also caused histological alterations in the liver. The study revealed that higher dose of TiO2 NPs exerted significantly harmful effects on liver and blood as compared to its lower doses as well as from all other doses of their bulk counterparts.

  19. Evaluation of the ANSR for Salmonella assay for identification of Salmonella spp. from colony picks from selective/differential agar media: first action 2013.14.

    Science.gov (United States)

    Mozola, Mark; Botimer, Maximilian; Jagadics, Carolyn; Norton, Paul; Caballero, Oscar; Enslin, Nicole; Biswas, Preetha; Rice, Jennifer

    2014-01-01

    A collaborative study was conducted to evaluate performance of the ANSR for Salmonella assay for identification of Salmonella spp. from colony picks taken from selective/differential agar media. The ANSR Salmonella assay is an isothermal nucleic acid amplification test based on the nicking enzyme amplification reaction chemistry. The test can be completed in less than 40 min including sample preparation. A total of 18 laboratories representing industry, government, academic, and commercial testing laboratories participated in the study. Each collaborator tested up to 84 samples, comprised of colony picks of six Salmonella spp. and six non-salmonellae taken from six selective/differential agar media as well as tryptic soy agar. A total of 1441 analyses were performed, 1416 of which gave the correct identification, for overall accuracy of 98.3%. For identification of Salmonella spp., 755 of 756 tests (99.9%) produced the correct result. For identification of non-salmonellae as such, 661 of 685 assays (96.5%) produced the correct result. Of the 18 laboratories, 15 produced data sets with 99-100% accuracy. The majority of false-positive results were clustered in three laboratories; analysis of raw data suggests procedural difficulties in at least two cases, which may explain the atypical data from these collaborators. The ANSR Salmonella assay can be used as a rapid, accurate adjunct or alternative to biochemical testing for identification of presumptive Salmonella spp. isolates.

  20. Challenges for bovine viral diarrhoea virus antibody detection in bulk milk by antibody enzyme-linked immunosorbent assays due to changes in milk production levels

    DEFF Research Database (Denmark)

    Foddai, Alessandro; Enøe, Claes; Stockmarr, Anders

    2015-01-01

    successfully been used to eradicate BVD in Sweden. Data (2003–2010) on changes in median herd size and milk production levels, occurrence of viremic animals and bulk milk surveillance were analysed. Additionally, the Danish blocking ELISA and the SVANOVIR ELISA were compared analyzing milk and serum samples....... The prevalence of antibody positive milking cows that could be detected by each test was estimated, by diluting positive individual milk samples and making artificial milk pools. Results: During the study period, the median herd size increased from 74 (2003) to 127 cows (2010), while the prevalence of BVDV...... infected herds decreased from 0.51 to 0.02 %. The daily milk yield contribution of a single seropositive cow to the entire daily bulk milk was reduced from 1.61 % in 2003 to 0.95 % in 2010 due to the increased herd size. It was observed that antibody levels in bulk milk decreased at national level...

  1. Bulk derivatization and cation exchange restricted access media-based trap-and-elute liquid chromatography–mass spectrometry method for determination of trace estrogens in serum

    Energy Technology Data Exchange (ETDEWEB)

    Beinhauer, Jana [Department of Biochemistry, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Centre of the Region Haná for Biotechnological and Agricultural Research - Department of Protein Biochemistry and Proteomics, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Bian, Liangqiao [Shimadzu Center for Advanced Analytical Chemistry, The University of Texas at Arlington, Arlington, TX (United States); Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); Fan, Hui [Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, TX (United States); Šebela, Marek [Department of Biochemistry, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Centre of the Region Haná for Biotechnological and Agricultural Research - Department of Protein Biochemistry and Proteomics, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Kukula, Maciej [Shimadzu Center for Advanced Analytical Chemistry, The University of Texas at Arlington, Arlington, TX (United States); Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); Barrera, Jose A. [Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); and others

    2015-02-09

    Highlights: • Analysis of estrogens in small volume samples at low parts-per-trillion concentration. • Charged bulk derivatization facilitates on-line ion exchange sample preparation. • On-line WCX restricted access media traps analytes, but not proteins and lipids. • Complete preparation and LC–MS/MS analysis completed in 30 min/sample. - Abstract: Estrone (E1), estradiols (α/β-E2), and estriol (E3) are four major metabolically active estrogens exerting strong biological activities at very low circulating concentrations. This paper reports a sensitive and efficient method with automated, on-line clean-up and detection to determine trace estrogens in a small volume of serum samples using liquid chromatography–electrospray ionization–tandem mass spectrometry directly, without off-line liquid–liquid or solid-phase extraction pretreatments. Serum aliquots (charcoal stripped fetal bovine serum, 100 μL) were spiked with four estrogen standards and their corresponding isotope-labeled internal standards, then bulk derivatized with 2-fluoro-1-methyl-pyridium p-toluenesulfonate (2-FMP) to establish the calibration curves and perform method validation. Calibration was established in the concentration ranges of 5–1000 pg mL{sup −1}, and demonstrated good linearity of R{sup 2} from 0.9944 to 0.9997 for the four derivatized estrogens. The lower detection limits obtained were 3–7 pg mL{sup −1}. Good accuracy and precision in the range of 86–112% and 2.3–11.9%, respectively, were observed for the quality control (QC) samples at low, medium, and high concentration levels. The stability tests showed that the derivatized serum samples were stable 8 h after derivatization at room temperature and at least to 48 h if stored at −20 °C. The method was applied to measure trace estrogens in real human and bovine serum samples, and three of four estrogen compounds studied were observed and quantified.

  2. A simple, rapid and reliable enzyme-linked immunosorbent assay for the detection of bovine virus diarrhoea virus (BVDV) specific antibodies in cattle serum, plasma and bulk milk

    NARCIS (Netherlands)

    Kramps, J.A.; Maanen, van C.; Wetering, van de G.; Stienstra, G.; Quak, S.; Brinkhof, J.; Ronsholt, L.; Nylin, B.

    1997-01-01

    To detect Bovine Virus Diarrhoea Virus (BVDV)-specific antibodies in cattle serum, plasma and bulk milk, a simple, reliable and rapid blocking ELISA ("Ceditest") has been developed using two monoclonal antibodies ("WB112" and "WB103") directed to different highly conserved epitopes on the non-struct

  3. Diagnostic performance of an indirect enzyme-linked immunosorbent assay (ELISA) to detect bovine leukemia virus antibodies in bulk-tank milk samples.

    Science.gov (United States)

    Nekouei, Omid; Durocher, Jean; Keefe, Greg

    2016-07-01

    This study assessed the diagnostic performance of a commercial ELISA for detecting bovine leukemia virus antibodies in bulk-tank milk samples from eastern Canada. Sensitivity and specificity of the test were estimated at 97.2% and 100%, respectively. The test was recommended as a cost-efficient tool for large-scale screening programs.

  4. Analysis and improvement of Brinkman lattice Boltzmann schemes: bulk, boundary, interface. Similarity and distinctness with finite elements in heterogeneous porous media.

    Science.gov (United States)

    Ginzburg, Irina; Silva, Goncalo; Talon, Laurent

    2015-02-01

    This work focuses on the numerical solution of the Stokes-Brinkman equation for a voxel-type porous-media grid, resolved by one to eight spacings per permeability contrast of 1 to 10 orders in magnitude. It is first analytically demonstrated that the lattice Boltzmann method (LBM) and the linear-finite-element method (FEM) both suffer from the viscosity correction induced by the linear variation of the resistance with the velocity. This numerical artefact may lead to an apparent negative viscosity in low-permeable blocks, inducing spurious velocity oscillations. The two-relaxation-times (TRT) LBM may control this effect thanks to free-tunable two-rates combination Λ. Moreover, the Brinkman-force-based BF-TRT schemes may maintain the nondimensional Darcy group and produce viscosity-independent permeability provided that the spatial distribution of Λ is fixed independently of the kinematic viscosity. Such a property is lost not only in the BF-BGK scheme but also by "partial bounce-back" TRT gray models, as shown in this work. Further, we propose a consistent and improved IBF-TRT model which vanishes viscosity correction via simple specific adjusting of the viscous-mode relaxation rate to local permeability value. This prevents the model from velocity fluctuations and, in parallel, improves for effective permeability measurements, from porous channel to multidimensions. The framework of our exact analysis employs a symbolic approach developed for both LBM and FEM in single and stratified, unconfined, and bounded channels. It shows that even with similar bulk discretization, BF, IBF, and FEM may manifest quite different velocity profiles on the coarse grids due to their intrinsic contrasts in the setting of interface continuity and no-slip conditions. While FEM enforces them on the grid vertexes, the LBM prescribes them implicitly. We derive effective LBM continuity conditions and show that the heterogeneous viscosity correction impacts them, a property also shared

  5. Development and validation of a single RP-HPLC assay method for analysis of bulk raw material batches of four parabens that are widely used as preservatives in pharmaceutical and cosmetic products.

    Science.gov (United States)

    Kumar, S; Mathkar, S; Romero, C; Rustum, A M

    2011-05-01

    A stability-indicating, robust, fast, and user friendly reversed-phase high-performance liquid chromatographic (RP-HPLC) assay method has been developed and validated for the analysis of commercial raw material batches of methylparaben, ethylparaben, propylparaben, and butylparaben. These four parabens are widely used as preservatives in pharmaceutical and cosmetic products. Accurate assay value of each of the parabens in their respective commercial lots is critical to determine the correct weight of the paraben that is needed to obtain the target concentration of the paraben in a specific lot of pharmaceutical or cosmetic products. Currently, there are no single HPLC assay methods (validated as per ICH requirements) available in the literature that can be used to analyze the commercial lots of each of the four parabens. The analytical method reported herein analyzes all four parabens in less than 10 min. The method presented in this report was successfully validated as per ICH guidelines. Therefore, this method can be implemented in QC laboratories to analyze and assay the commercial bulk lots of the four parabens.

  6. Laboratory Performance of Five Selected Soil Moisture Sensors Applying Factory and Own Calibration Equations for Two Soil Media of Different Bulk Density and Salinity Levels.

    Science.gov (United States)

    Matula, Svatopluk; Báťková, Kamila; Legese, Wossenu Lemma

    2016-11-15

    Non-destructive soil water content determination is a fundamental component for many agricultural and environmental applications. The accuracy and costs of the sensors define the measurement scheme and the ability to fit the natural heterogeneous conditions. The aim of this study was to evaluate five commercially available and relatively cheap sensors usually grouped with impedance and FDR sensors. ThetaProbe ML2x (impedance) and ECH₂O EC-10, ECH₂O EC-20, ECH₂O EC-5, and ECH₂O TE (all FDR) were tested on silica sand and loess of defined characteristics under controlled laboratory conditions. The calibrations were carried out in nine consecutive soil water contents from dry to saturated conditions (pure water and saline water). The gravimetric method was used as a reference method for the statistical evaluation (ANOVA with significance level 0.05). Generally, the results showed that our own calibrations led to more accurate soil moisture estimates. Variance component analysis arranged the factors contributing to the total variation as follows: calibration (contributed 42%), sensor type (contributed 29%), material (contributed 18%), and dry bulk density (contributed 11%). All the tested sensors performed very well within the whole range of water content, especially the sensors ECH₂O EC-5 and ECH₂O TE, which also performed surprisingly well in saline conditions.

  7. Zirconium-metalloporphyrin frameworks as a three-in-one platform possessing oxygen nanocage, electron media, and bonding site for electrochemiluminescence protein kinase activity assay

    Science.gov (United States)

    Zhang, Guang-Yao; Cai, Chang; Cosnier, Serge; Zeng, Hai-Bo; Zhang, Xue-Ji; Shan, Dan

    2016-06-01

    A Zr-based metal-organic framework with zinc tetrakis(carboxyphenyl)-porphyrin (ZnTCPP) groups (MOF-525-Zn) was utilized to develop a novel electrochemiluminescence (ECL) biosensor for highly sensitive protein kinase activity assay. In this work, in terms of ECL measurements and cyclic voltammetry, the cathodic ECL behaviors of MOF-525-Zn in aqueous media were thoroughly investigated for the first time. The photoelectric active groups ZnTCPP on the MOF-525-Zn frameworks could promote the generation of singlet oxygen (1O2) via a series of electrochemical and chemical reactions, resulting in a strong and stable red irradiation at 634 nm. Additionally, the surfactant tetraoctylammonium bromide (TOAB) further facilitated dissolved oxygen to interact with the active sites ZnTCPP of MOF-525-Zn. Furthermore, the inorganic Zr-O clusters of MOF-525-Zn were simultaneously served as the recognition sites of phosphate groups. And then, an ultrasensitive ECL sensor was proposed for protein kinase A (PKA) activity detection with a linear range from 0.01 to 20 U mL-1 and a sensitive detection limit of 0.005 U mL-1. This biosensor can also be applied for quantitative kinase inhibitor screening. Finally, it exhibits good performance with high stability and acceptable fabrication reproducibility, which provide a valuable strategy for clinic diagnostics and therapeutics.A Zr-based metal-organic framework with zinc tetrakis(carboxyphenyl)-porphyrin (ZnTCPP) groups (MOF-525-Zn) was utilized to develop a novel electrochemiluminescence (ECL) biosensor for highly sensitive protein kinase activity assay. In this work, in terms of ECL measurements and cyclic voltammetry, the cathodic ECL behaviors of MOF-525-Zn in aqueous media were thoroughly investigated for the first time. The photoelectric active groups ZnTCPP on the MOF-525-Zn frameworks could promote the generation of singlet oxygen (1O2) via a series of electrochemical and chemical reactions, resulting in a strong and stable red

  8. Bulk Moisture and Salinity Sensor

    Science.gov (United States)

    Nurge, Mark; Monje, Oscar; Prenger, Jessica; Catechis, John

    2013-01-01

    Measurement and feedback control of nutrient solutions in plant root zones is critical to the development of healthy plants in both terrestrial and reduced-gravity environments. In addition to the water content, the amount of fertilizer in the nutrient solution is important to plant health. This typically requires a separate set of sensors to accomplish. A combination bulk moisture and salinity sensor has been designed, built, and tested with different nutrient solutions in several substrates. The substrates include glass beads, a clay-like substrate, and a nutrient-enriched substrate with the presence of plant roots. By measuring two key parameters, the sensor is able to monitor both the volumetric water content and salinity of the nutrient solution in bulk media. Many commercially available moisture sensors are point sensors, making localized measurements over a small volume at the point of insertion. Consequently, they are more prone to suffer from interferences with air bubbles, contact area of media, and root growth. This makes it difficult to get an accurate representation of true moisture content and distribution in the bulk media. Additionally, a network of point sensors is required, increasing the cabling, data acquisition, and calibration requirements. measure the dielectric properties of a material in the annular space of the vessel. Because the pore water in the media often has high salinity, a method to measure the media moisture content and salinity simultaneously was devised. Characterization of the frequency response for capacitance and conductance across the electrodes was completed for 2-mm glass bead media, 1- to 2-mm Turface (a clay like media), and 1- to 2-mm fertilized Turface with the presence of root mass. These measurements were then used to find empirical relationships among capacitance (C), the dissipation factor (D), the volumetric water content, and the pore water salinity.

  9. Next-Generation Sequencing Combined with Specific PCR Assays To Determine the Bacterial 16S rRNA Gene Profiles of Middle Ear Fluid Collected from Children with Acute Otitis Media

    Science.gov (United States)

    Kramna, Lenka; Oikarinen, Sami; Sipilä, Markku; Rautiainen, Markus; Aittoniemi, Janne; Laranne, Jussi; Hyöty, Heikki; Cinek, Ondrej

    2017-01-01

    ABSTRACT The aim of the study was to analyze the bacteriome of acute otitis media with a novel modification of next-generation sequencing techniques. Outpatient children with acute otitis media were enrolled in the study, and middle ear fluids were collected during 90 episodes from 79 subjects aged 5 to 42 months (median age, 19 months). The bacteriome profiles of middle ear fluid samples were determined by a nested-PCR amplification of the 16S rRNA gene (V4 region), followed by mass sequencing. The profiling results were compared to the results of specific PCR assays targeting selected prevalent pathogens. Bacteriome profiling using nested amplification of low-volume samples was aided by a bioinformatic subtraction of signal contaminants from the recombinant polymerase, achieving a sensitivity slightly lower than that of specific PCR detection. Streptococcus pneumoniae was detected in 28 (31%) samples, Haemophilus influenzae in 24 (27%), Moraxella catarrhalis in 18 (20%), Staphylococcus spp. in 21 (23%), Turicella otitidis in 5 (5.6%), Alloiococcus otitidis in 3 (3.3%), and other bacteria in 14 (16%) using bacteriome profiling. S. pneumoniae was the dominant pathogen in 14 (16%) samples, H. influenzae in 15 (17%), M. catarrhalis in 5 (5.6%), T. otitidis in 2, and Staphylococcus auricularis in 2. Weaker signals of Prevotella melaninogenica, Veillonella dispar, and Veillonella montpellierensis were noted in several samples. Fourteen samples (16%) were not explainable by bacterial pathogens; novel causative agents were not detected. In conclusion, unbiased bacteriome profiling helped in depicting the true mutual quantitative ratios of ear bacteria, but at present, its complicated protocol impedes its routine clinical use. IMPORTANCE Although S. pneumoniae, H. influenzae, and M. catarrhalis have been long established as the most important pathogens in acute otitis media using culture and specific PCR assays, the knowledge of their mutual quantitative relations

  10. Carbon nanotubes grown on bulk materials and methods for fabrication

    Science.gov (United States)

    Menchhofer, Paul A.; Montgomery, Frederick C.; Baker, Frederick S.

    2011-11-08

    Disclosed are structures formed as bulk support media having carbon nanotubes formed therewith. The bulk support media may comprise fibers or particles and the fibers or particles may be formed from such materials as quartz, carbon, or activated carbon. Metal catalyst species are formed adjacent the surfaces of the bulk support material, and carbon nanotubes are grown adjacent the surfaces of the metal catalyst species. Methods employ metal salt solutions that may comprise iron salts such as iron chloride, aluminum salts such as aluminum chloride, or nickel salts such as nickel chloride. Carbon nanotubes may be separated from the carbon-based bulk support media and the metal catalyst species by using concentrated acids to oxidize the carbon-based bulk support media and the metal catalyst species.

  11. Gold Nanoparticles-based Extraction-Free Colorimetric Assay in Organic Media: An Optical Index for Determination of Total Polyphenols in Fat-Rich Samples.

    Science.gov (United States)

    Della Pelle, Flavio; González, María Cristina; Sergi, Manuel; Del Carlo, Michele; Compagnone, Dario; Escarpa, Alberto

    2015-07-07

    In this work, a rapid and simple gold nanoparticle (AuNPs)-based colorimetric assay meets a new type of synthesis of AuNPs in organic medium requiring no sample extraction. The AuNPs synthesis extraction-free approach strategically involves the use of dimethyl sulfoxide (DMSO) acting as an organic solvent for simultaneous sample analyte solubilization and AuNPs stabilization. Moreover, DMSO works as a cryogenic protector avoiding solidification at the temperatures used to block the synthesis. In addition, the chemical function as AuNPs stabilizers of the sample endogenous fatty acids is also exploited, avoiding the use of common surfactant AuNPs stabilizers, which, in an organic/aqueous medium, rise to the formation of undesirable emulsions. This is controlled by adding a fat analyte free sample (sample blank). The method was exhaustively applied for the determination of total polyphenols in two selected kinds of fat-rich liquid and solid samples with high antioxidant activity and economic impact: olive oil (n = 28) and chocolate (n = 16) samples. Fatty sample absorbance is easily followed by the absorption band of localized surface plasmon resonance (LSPR) at 540 nm and quantitation is refereed to gallic acid equivalents. A rigorous evaluation of the method was performed by comparison with the well and traditionally established Folin-Ciocalteu (FC) method, obtaining an excellent correlation for olive oil samples (R = 0.990, n = 28) and for chocolate samples (R = 0.905, n = 16). Additionally, it was also found that the proposed approach was selective (vs other endogenous sample tocopherols and pigments), fast (15-20 min), cheap and simple (does not require expensive/complex equipment), with a very limited amount of sample (30 μL) needed and a significant lower solvent consumption (250 μL in 500 μL total reaction volume) compared to classical methods.

  12. Large area bulk superconductors

    Science.gov (United States)

    Miller, Dean J.; Field, Michael B.

    2002-01-01

    A bulk superconductor having a thickness of not less than about 100 microns is carried by a polycrystalline textured substrate having misorientation angles at the surface thereof not greater than about 15.degree.; the bulk superconductor may have a thickness of not less than about 100 microns and a surface area of not less than about 50 cm.sup.2. The textured substrate may have a thickness not less than about 10 microns and misorientation angles at the surface thereof not greater than about 15.degree.. Also disclosed is a process of manufacturing the bulk superconductor and the polycrystalline biaxially textured substrate material.

  13. Enzyme assays.

    Science.gov (United States)

    Reymond, Jean-Louis; Fluxà, Viviana S; Maillard, Noélie

    2009-01-07

    Enzyme assays are analytical tools to visualize enzyme activities. In recent years a large variety of enzyme assays have been developed to assist the discovery and optimization of industrial enzymes, in particular for "white biotechnology" where selective enzymes are used with great success for economically viable, mild and environmentally benign production processes. The present article highlights the aspects of fluorogenic and chromogenic substrates, sensors, and enzyme fingerprinting, which are our particular areas of interest.

  14. Cross-correlation frequency-resolved optical gating of white-light continuum (500-900 nm) generated in bulk media by 1053 nm laser pulses

    Science.gov (United States)

    Imran, T.; Hussain, M.; Figueira, G.

    2016-06-01

    We have efficiently characterized the white-light continuum (WLC) generation covering 500-900 nm in a bulk sapphire plate using 280 fs pulse duration, 1053 nm center-wavelength seed laser pulses. We have acquired the well-optimized smoother region of the WLC spectrum successfully by using an FGS-900 color glass filter (Edmund Optics, Inc.). We have suppressed the spectral components below 500 nm and over 900 nm including an intense 1053 nm residual seed laser peak of the WLC spectrum. The experimental artifacts have been avoided by suppressing the intense 1053 nm seed laser. We employed the sum frequency generation cross-correlation frequency-resolved optical gating (SFG-XFROG) technique for characterization. The XFROG measurement was carried out by introducing the crystal dithering method up to 10° in 2° intervals to obtain the phase matching effectively over the filtered and smoother region of the WLC spectrum. This well-optimized WLC region covering 500-900 nm has significant importance for use as a seed pulse in an optical parametric chirped pulse amplification (OPCPA) system.

  15. Bulk chemicals from biomass

    NARCIS (Netherlands)

    Haveren, van J.; Scott, E.L.; Sanders, J.P.M.

    2008-01-01

    Given the current robust forces driving sustainable production, and available biomass conversion technologies, biomass-based routes are expected to make a significant impact on the production of bulk chemicals within 10 years, and a huge impact within 20-30 years. In the Port of Rotterdam there is a

  16. Radiative Bulk Viscosity

    CERN Document Server

    Chen, X

    2001-01-01

    Viscous resistance to changes in the volume of a gas arises when different degrees of freedom have different relaxation times. Collisions tend to oppose the resulting departures from equilibrium and, in so doing, generate entropy. Even for a classical gas of hard spheres, when the mean free paths or mean flight times of constituent particles are long, we find a nonvanishing bulk viscosity. Here we apply a method recently used to uncover this result for a classical rarefied gas to radiative transfer theory and derive an expression for the radiative stress tensor for a gray medium with absorption and Thomson scattering. We determine the transport coefficients through the calculation of the comoving entropy generation. When scattering dominates absorption, the bulk viscosity becomes much larger than either the shear viscosity or the thermal conductivity.

  17. Media education.

    Science.gov (United States)

    Strasburger, Victor C

    2010-11-01

    The American Academy of Pediatrics recognizes that exposure to mass media (eg, television, movies, video and computer games, the Internet, music lyrics and videos, newspapers, magazines, books, advertising) presents health risks for children and adolescents but can provide benefits as well. Media education has the potential to reduce the harmful effects of media and accentuate the positive effects. By understanding and supporting media education, pediatricians can play an important role in reducing harmful effects of media on children and adolescents.

  18. Media violence.

    Science.gov (United States)

    Strasburger, V C

    1999-01-01

    For decades, media violence has been viewed as largely a Western problem. New studies indicate that Indian children have increasing access to the media and that media violence will subject them to the same problems as Western children: imitation, desensitization, fear, and inappropriate attitudes about violence and aggression. Solutions exist but will have to be implemented within the next decade to protect Indian children and adolescents from the harmful effects of media violence.

  19. Bulk-Fill Resin Composites

    DEFF Research Database (Denmark)

    Benetti, Ana Raquel; Havndrup-Pedersen, Cæcilie; Honoré, Daniel;

    2015-01-01

    the restorative procedure. The aim of this study, therefore, was to compare the depth of cure, polymerization contraction, and gap formation in bulk-fill resin composites with those of a conventional resin composite. To achieve this, the depth of cure was assessed in accordance with the International Organization...... for Standardization 4049 standard, and the polymerization contraction was determined using the bonded-disc method. The gap formation was measured at the dentin margin of Class II cavities. Five bulk-fill resin composites were investigated: two high-viscosity (Tetric EvoCeram Bulk Fill, SonicFill) and three low......-viscosity (x-tra base, Venus Bulk Fill, SDR) materials. Compared with the conventional resin composite, the high-viscosity bulk-fill materials exhibited only a small increase (but significant for Tetric EvoCeram Bulk Fill) in depth of cure and polymerization contraction, whereas the low-viscosity bulk...

  20. The Incredible Bulk

    CERN Document Server

    Fukushima, Keita; Kumar, Jason; Sandick, Pearl; Yamamoto, Takahiro

    2014-01-01

    Recent experimental results from the LHC have placed strong constraints on the masses of colored superpartners. The MSSM parameter space is also constrained by the measurement of the Higgs boson mass, and the requirement that the relic density of lightest neutralinos be consistent with observations. Although large regions of the MSSM parameter space can be excluded by these combined bounds, leptophilic versions of the MSSM can survive these constraints. In this paper we consider a scenario in which the requirements of minimal flavor violation, vanishing $CP$-violation, and mass universality are relaxed, specifically focusing on scenarios with light sleptons. We find a large region of parameter space, analogous to the original bulk region, for which the lightest neutralino is a thermal relic with an abundance consistent with that of dark matter. We find that these leptophilic models are constrained by measurements of the magnetic and electric dipole moments of the electron and muon, and that these models have ...

  1. Creating bulk nanocrystalline metal.

    Energy Technology Data Exchange (ETDEWEB)

    Fredenburg, D. Anthony (Georgia Institute of Technology, Atlanta, GA); Saldana, Christopher J. (Purdue University, West Lafayette, IN); Gill, David D.; Hall, Aaron Christopher; Roemer, Timothy John (Ktech Corporation, Albuquerque, NM); Vogler, Tracy John; Yang, Pin

    2008-10-01

    Nanocrystalline and nanostructured materials offer unique microstructure-dependent properties that are superior to coarse-grained materials. These materials have been shown to have very high hardness, strength, and wear resistance. However, most current methods of producing nanostructured materials in weapons-relevant materials create powdered metal that must be consolidated into bulk form to be useful. Conventional consolidation methods are not appropriate due to the need to maintain the nanocrystalline structure. This research investigated new ways of creating nanocrystalline material, new methods of consolidating nanocrystalline material, and an analysis of these different methods of creation and consolidation to evaluate their applicability to mesoscale weapons applications where part features are often under 100 {micro}m wide and the material's microstructure must be very small to give homogeneous properties across the feature.

  2. Explosive bulk charge

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Jacob Lee

    2015-04-21

    An explosive bulk charge, including: a first contact surface configured to be selectively disposed substantially adjacent to a structure or material; a second end surface configured to selectively receive a detonator; and a curvilinear side surface joining the first contact surface and the second end surface. The first contact surface, the second end surface, and the curvilinear side surface form a bi-truncated hemispherical structure. The first contact surface, the second end surface, and the curvilinear side surface are formed from an explosive material. Optionally, the first contact surface and the second end surface each have a substantially circular shape. Optionally, the first contact surface and the second end surface consist of planar structures that are aligned substantially parallel or slightly tilted with respect to one another. The curvilinear side surface has one of a smooth curved geometry, an elliptical geometry, and a parabolic geometry.

  3. Media Flow

    DEFF Research Database (Denmark)

    Kabel, Lars

    2016-01-01

    News and other kinds of journalistic stories, 16-17 hours a day, all year round, on all platforms, also the moderated social media. The key research thesis behind this article is that the continuous and speedy stream of news stories and media content now is becoming the centre of the production...... processes and the value creation in converged multimedia newsrooms. The article identify new methods and discuss editorial challenges in handling media flow....

  4. Mass Media

    Institute of Scientific and Technical Information of China (English)

    叶全荣

    2006-01-01

    @@ Every day,we are all influenced by the mass media.Although some critics of the media claim that these means of communication are used mainly to control our thinking and get us to buy products that we don't need,the media also contribute to keeping people informed.In other words,while dangers do exist,the benefits of the media far outweigh(超过)the disadvantages.Most of the messages brought to viewers,listeners,and readers are designed either to inform or to entertain,and neither of these goals can be considered dangerous or harmful.

  5. Can bulk viscosity drive inflation

    Energy Technology Data Exchange (ETDEWEB)

    Pacher, T.; Stein-Schabes, J.A.; Turner, M.S.

    1987-09-15

    Contrary to other claims, we argue that bulk viscosity associated with the interactions of non- relativistic particles with relativistic particles around the time of the grand unified theory (GUT) phase transition cannot lead to inflation. Simply put, the key ingredient for inflation, negative pressure, cannot arise due to the bulk-viscosity effects of a weakly interacting mixture of relativistic and nonrelativistic particles.

  6. Brane Couplings from Bulk Loops

    OpenAIRE

    Georgi, Howard; Grant, Aaron K.; Hailu, Girma

    2000-01-01

    We compute loop corrections to the effective action of a field theory on a five-dimensional $S_1/Z_2$ orbifold. We find that the quantum loop effects of interactions in the bulk produce infinite contributions that require renormalization by four-dimensional couplings on the orbifold fixed planes. Thus bulk couplings give rise to renormalization group running of brane couplings.

  7. Mixed Media

    Science.gov (United States)

    Peterson, Erin

    2010-01-01

    While institutions do not often have a hook as compelling as an eagerly awaited movie, great content is critical for media relations success--and coupling it with the right distribution channel can ensure the story finds the right audience. Even better, retooling it for several media platforms can extend the life and reach of a story. The changes…

  8. Media places

    DEFF Research Database (Denmark)

    Linde, Per; Messeter, Jörn

    for the Media places project, give some brief insights into the themes of setting up temporary digital streams of media and mobile games. Considering the work-in-progress character of the research and the smaller format of text, no real in-depth analysis will be carried out. The goal is rather to position...

  9. Media darling

    CERN Multimedia

    Chalmers, Matthew

    2008-01-01

    He is the media-friendly face of particle physics, appearing on countless TV and radio shows in the run-up to the opening of CERN's Large Hadron Collider. Matthew Chalmers discovers how Brian Cox finds the time to be both a physicist and a media personality. (2 pages)

  10. Media violence.

    Science.gov (United States)

    Cantor, J

    2000-08-01

    Research on the effects of media violence is not well understood by the general public. Despite this fact, there is an overwhelming consensus in the scientific literature about the unhealthy effects of media violence. Meta-analyses show that media-violence viewing consistently is associated with higher levels of antisocial behavior, ranging from the trivial (imitative violence directed against toys) to the serious (criminal violence), with many consequential outcomes in between (acceptance of violence as a solution to problems, increased feelings of hostility, and the apparent delivery of painful stimulation to another person). Desensitization is another well-documented effect of viewing violence, which is observable in reduced arousal and emotional disturbance while witnessing violence, the reduced tendency to intervene in a fight, and less sympathy for the victims of violence. Although there is evidence that youth who are already violent are more likely to seek out violent entertainment, there is strong evidence that the relationship between violence viewing and antisocial behavior is bidirectional. There is growing evidence that media violence also engenders intense fear in children which often lasts days, months, and even years. The media's potential role in solutions to these problems is only beginning to be explored, in investigations examining the uses and effects of movie ratings, television ratings, and the V-chip, and the effects of media literacy programs and public education efforts. Future research should explore important individual differences in responses to media violence and effective ways to intervene in the negative effects.

  11. Signed Networks in Social Media

    OpenAIRE

    Leskovec, Jure; Huttenlocher, Daniel; Kleinberg, Jon

    2010-01-01

    Relations between users on social media sites often reflect a mixture of positive (friendly) and negative (antagonistic) interactions. In contrast to the bulk of research on social networks that has focused almost exclusively on positive interpretations of links between people, we study how the interplay between positive and negative relationships affects the structure of on-line social networks. We connect our analyses to theories of signed networks from social psychology. We find that the c...

  12. From Augmentation Media to Meme Media.

    Science.gov (United States)

    Tanaka, Yuzuru

    Computers as meta media are now evolving from augmentation media vehicles to meme media vehicles. While an augmentation media system provides a seamlessly integrated environment of various tools and documents, meme media system provides further functions to edit and distribute tools and documents. Documents and tools on meme media can easily…

  13. Community Media: Muting the Democratic Media Discourse?

    NARCIS (Netherlands)

    Carpentier, N.; Lie, R.; Servaes, J.

    2003-01-01

    Focuses on the concept of community media. Components that construct the identity of community media; Multi-theoretical approaches for analysis of community media; Definition of community media based on the concept of alternative media; Link between community media and civil society; Problems faced

  14. Can bulk viscosity drive inflation

    Energy Technology Data Exchange (ETDEWEB)

    Pacher, T.; Stein-Schabes, J.A.; Turner, M.S.

    1987-04-01

    Contrary to other claims, we argue that, bulk viscosity associated with the interactions of nonrelativistic particles with relativistic particles around the time of the grand unified theory (GUT) phase transition cannot lead to inflation. Simply put, the key ingredient for inflation, negative pressure, cannot arise due to the bulk viscosity effects of a weakly-interacting mixture of relativistic and nonrelativistic particles. 13 refs., 1 fig.

  15. Social Media

    OpenAIRE

    2013-01-01

    Anlässlich der 10. Wissenschaftlichen Tagung „Soziale Medien“ am 27. und 28. Juni 2013 im Statistischen Bundesamt in Wiesbaden und in Fortsetzung des 2010 erschienenen Recherche Spezial Web 2.0 – Alle machen mit! werden in dieser Ausgabe in sechs Kapiteln Nachweise zu Veröffentlichungen und Forschungsprojekte der letzten drei Jahre zusammengestellt, die sich mit der Rolle von Social Media in verschiedenen Nutzungskontexten befassen. Social-Media-Dienste sind mittlerweile fester Bestandtei...

  16. Media Bias

    OpenAIRE

    Sendhil Mullainathan; Andrei Shleifer

    2002-01-01

    There are two different types of media bias. One bias, which we refer to as ideology, reflects a news outlet's desire to affect reader opinions in a particular direction. The second bias, which we refer to as spin, reflects the outlet's attempt to simply create a memorable story. We examine competition among media outlets in the presence of these biases. Whereas competition can eliminate the effect of ideological bias, it actually exaggerates the incentive to spin stories.

  17. Cytotoxic effects of bulk fill composite resins on human dental pulp stem cells.

    Science.gov (United States)

    Şişman, Reyhan; Aksoy, Ayça; Yalçın, Muhammet; Karaöz, Erdal

    2016-01-01

    Five bulk fill composite resins, including SDR, Tetric EvoCeram Bulk Fill (TEC), X-trafil (XTF), Sonic Fill (SF), Filtek Bulk Fill (FBF), were used in this study. Human dental pulp stem cells were cultured in 12-well culture dishes (3 × 104 cells per cm(2)) and stored in an incubator at 37°C and 5% CO2 for 1 day. On days 1, 7, 14, and 21 of co-culture, viable cells were measured using a WST-1 assay. Lower cell viability was observed with XTF and SDR bulk fill composite resins compared to the control group during the WST-1 assay. Although bulk fill composite resins provide advantages in practical applications, they are limited by their cytotoxic properties. (J Oral Sci 58, 299-305, 2016).

  18. Looking for a bulk point

    CERN Document Server

    Maldacena, Juan; Zhiboedov, Alexander

    2015-01-01

    We consider Lorentzian correlators of local operators. In perturbation theory, singularities occur when we can draw a position-space Landau diagram with null lines. In theories with gravity duals, we can also draw Landau diagrams in the bulk. We argue that certain singularities can arise only from bulk diagrams, not from boundary diagrams. As has been previously observed, these singularities are a clear diagnostic of bulk locality. We analyze some properties of these perturbative singularities and discuss their relation to the OPE and the dimensions of double-trace operators. In the exact nonperturbative theory, we expect no singularity at these locations. We prove this statement in 1+1 dimensions by CFT methods.

  19. Media Training

    CERN Document Server

    CERN. Geneva

    2009-01-01

    With the LHC starting up soon, the world's media are again turning their attention to CERN. We're all likely to be called upon to explain what is happening at CERN to media, friends and neighbours. The seminar will be given by BBC television news journalists Liz Pike and Nadia Marchant, and will deal with the kind of questions we're likely to be confronted with through the restart period. The training is open for everybody. Make sure you arrive early enough to get a seat - there are only 200 seats in the Globe. The session will also be webcast: http://webcast.cern.ch/

  20. Bulk nano-crystalline alloys

    OpenAIRE

    T.-S. Chin; Lin, C. Y.; Lee, M.C.; R.T. Huang; S. M. Huang

    2009-01-01

    Bulk metallic glasses (BMGs) Fe–B–Y–Nb–Cu, 2 mm in diameter, were successfully annealed to become bulk nano-crystalline alloys (BNCAs) with α-Fe crystallite 11–13 nm in size. A ‘crystallization-and-stop’ model was proposed to explain this behavior. Following this model, alloy-design criteria were elucidated and confirmed successful on another Fe-based BMG Fe–B–Si–Nb–Cu, 1 mm in diameter, with crystallite sizes 10–40 nm. It was concluded that BNCAs can be designed in general by the proposed cr...

  1. Social Media

    Science.gov (United States)

    2010-05-01

    Digital Marketing and Ecommerce Professionals. 29 January 2010. 20 May 2010. <http://econsultancy.com/blog/5324-20+-mind-blowing-social- media...Statistics Revisited.” Econsultancy | Community of Digital Marketing and Ecommerce Professionals. 29 Jan. 2010. 20 May 2010. <http://econsultancy.com/blog

  2. Streaming Media

    Science.gov (United States)

    Pulley, John

    2009-01-01

    At a time when the evolutionary pace of new media resembles the real-time mutation of certain microorganisms, the age-old question of how best to connect with constituents can seem impossibly complex--even for an elite institution plugged into the motherboard of Silicon Valley. Identifying the most effective vehicle for reaching a particular…

  3. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja

    2009-01-01

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise i...

  4. The Universe With Bulk Viscosity

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Exact solutions for a model with variable G, A and bulk viscosity areobtained. Inflationary solutions with constant (de Sitter-type) and variable energydensity are found. An expanding anisotropic universe is found to isotropize duringits expansion but a static universe cannot isotropize. The gravitational constant isfound to increase with time and the cosmological constant decreases with time asAo∝t-2.

  5. [Chronic otitis mediaChronic Otitis Media].

    Science.gov (United States)

    Kohles, N; Schulz, T; Eßer, D

    2015-11-01

    There are 2 different kinds of chronic otitis media: Otitis media chronica mesotympanalis and otitis media chronica epitympanalis (cholesteatoma). The incidence of chronic otitis media as reported in literature differs in a wide range. The incidence rates vary between 0.45 and 46%. Both, otitis media chronica mesotympanalis and cholesteatoma, lead to eardrum perforation due to lengthy and recurring inflammations. Furthermore, chronic otitis media is characterized by frequently recurring otorrhea and conductive hearing loss.

  6. Otitis media with effusion

    Science.gov (United States)

    OME; Secretory otitis media; Serous otitis media; Silent otitis media; Silent ear infection; Glue ear ... fluid drains from the tube and is swallowed. Otitis media with effusion (OME) and ear infections are ...

  7. Media matters.

    Science.gov (United States)

    Martinez, L M

    1995-01-01

    The impact of the mass media on woman's status was addressed at two 1995 conferences: the Fourth World Conference on Women, held in Beijing, China, and the Congress of the World Association for Christian Communication, held in Puebla, Mexico. The globalization process facilitated by the mass media has served to increase the power of patriarchy, with no advantages to the cause of women's rights. Coverage of popular movements has been suppressed out of deference to male-controlled governments. Coverage of the Beijing Conference highlighted celebrities and personal stories, to the exclusion of the economic and political issues under debate. Television has commodified women, reinforcing their oppression. On the other hand, the alternative media, which tend to be decentralized, democratic, low-cost, and low in technology, are presenting women as subjects rather than objects and deconstructing gender stereotypes. Of concern, however, is the tendency of computer technology to widen the gap between social classes and developed and developing countries. Women must use information networks to disseminate information on women's rights and strengthen the links between women throughout the world.

  8. Bulk viscous cosmology: statefinder and entropy

    CERN Document Server

    He, X

    2006-01-01

    The statefinder diagnostic pair is adopted to differentiate viscous cosmology models and it is found that the trajectories of these viscous cosmology models on the statefinder pair $s-r$ plane are quite different from those of the corresponding non-viscous cases. Particularly for the quiessence model, the singular properties of state parameter $w=-1$ are obviously demonstrated on the statefinder diagnostic pair planes. We then discuss the entropy of the viscous / dissipative cosmology system which may be more practical to describe the present cosmic observations as the perfect fluid is just a global approximation to the complicated cosmic media in current universe evolution. When the bulk viscosity takes the form of $\\zeta=\\zeta_{1}\\dot{a}/a$($\\zeta_{1}$ is constant), the relationship between the entropy $S$ and the redshift $z$ is explicitly given out. We find that the entropy of the viscous cosmology is always increasing and consistent with the thermodynamics arrow of time for the universe evolution. With t...

  9. Media Education Initiatives by Media Organizations: The Uses of Media Literacy in Hong Kong Media

    Science.gov (United States)

    Chu, Donna; Lee, Alice Y. L.

    2014-01-01

    As more media organizations have engaged in media education, this paper investigates the goals and practices of these activities. This article coins media education initiatives by media organizations with the term "media-organization media literac"y (MOML). Four MOML projects in Hong Kong were selected for examination. Built on critical…

  10. Bulk Superconductors in Mobile Application

    Science.gov (United States)

    Werfel, F. N.; Delor, U. Floegel-; Rothfeld, R.; Riedel, T.; Wippich, D.; Goebel, B.; Schirrmeister, P.

    We investigate and review concepts of multi - seeded REBCO bulk superconductors in mobile application. ATZ's compact HTS bulk magnets can trap routinely 1 T@77 K. Except of magnetization, flux creep and hysteresis, industrial - like properties as compactness, power density, and robustness are of major device interest if mobility and light-weight construction is in focus. For mobile application in levitated trains or demonstrator magnets we examine the performance of on-board cryogenics either by LN2 or cryo-cooler application. The mechanical, electric and thermodynamical requirements of compact vacuum cryostats for Maglev train operation were studied systematically. More than 30 units are manufactured and tested. The attractive load to weight ratio is more than 10 and favours group module device constructions up to 5 t load on permanent magnet (PM) track. A transportable and compact YBCO bulk magnet cooled with in-situ 4 Watt Stirling cryo-cooler for 50 - 80 K operation is investigated. Low cooling power and effective HTS cold mass drives the system construction to a minimum - thermal loss and light-weight design.

  11. Microbead agglutination based assays

    KAUST Repository

    Kodzius, Rimantas

    2013-01-21

    We report a simple and rapid room temperature assay for point-of-care (POC) testing that is based on specific agglutination. Agglutination tests are based on aggregation of microbeads in the presence of a specific analyte thus enabling the macroscopic observation. Such tests are most often used to explore antibody-antigen reactions. Agglutination has been used for protein assays using a biotin/streptavidin system as well as a hybridization based assay. The agglutination systems are prone to selftermination of the linking analyte, prone to active site saturation and loss of agglomeration at high analyte concentrations. We investigated the molecular target/ligand interaction, explaining the common agglutination problems related to analyte self-termination, linkage of the analyte to the same bead instead of different microbeads. We classified the agglutination process into three kinds of assays: a two- component assay, a three-component assay and a stepped three- component assay. Although we compared these three kinds of assays for recognizing DNA and protein molecules, the assay can be used for virtually any molecule, including ions and metabolites. In total, the optimized assay permits detecting analytes with high sensitivity in a short time, 5 min, at room temperature. Such a system is appropriate for POC testing.

  12. Colorimetric protein assay techniques.

    Science.gov (United States)

    Sapan, C V; Lundblad, R L; Price, N C

    1999-04-01

    There has been an increase in the number of colorimetric assay techniques for the determination of protein concentration over the past 20 years. This has resulted in a perceived increase in sensitivity and accuracy with the advent of new techniques. The present review considers these advances with emphasis on the potential use of such technologies in the assay of biopharmaceuticals. The techniques reviewed include Coomassie Blue G-250 dye binding (the Bradford assay), the Lowry assay, the bicinchoninic acid assay and the biuret assay. It is shown that each assay has advantages and disadvantages relative to sensitivity, ease of performance, acceptance in the literature, accuracy and reproducibility/coefficient of variation/laboratory-to-laboratory variation. A comparison of the use of several assays with the same sample population is presented. It is suggested that the most critical issue in the use of a chromogenic protein assay for the characterization of a biopharmaceutical is the selection of a standard for the calibration of the assay; it is crucial that the standard be representative of the sample. If it is not possible to match the standard with the sample from the perspective of protein composition, then it is preferable to use an assay that is not sensitive to the composition of the protein such as a micro-Kjeldahl technique, quantitative amino acid analysis or the biuret assay. In a complex mixture it might be inappropriate to focus on a general method of protein determination and much more informative to use specific methods relating to the protein(s) of particular interest, using either specific assays or antibody-based methods. The key point is that whatever method is adopted as the 'gold standard' for a given protein, this method needs to be used routinely for calibration.

  13. Toughness of Bulk Metallic Glasses

    Directory of Open Access Journals (Sweden)

    Shantanu V. Madge

    2015-07-01

    Full Text Available Bulk metallic glasses (BMGs have desirable properties like high strength and low modulus, but their toughness can show much variation, depending on the kind of test as well as alloy chemistry. This article reviews the type of toughness tests commonly performed and the factors influencing the data obtained. It appears that even the less-tough metallic glasses are tougher than oxide glasses. The current theories describing the links between toughness and material parameters, including elastic constants and alloy chemistry (ordering in the glass, are discussed. Based on the current literature, a few important issues for further work are identified.

  14. Absolute nuclear material assay

    Science.gov (United States)

    Prasad, Manoj K [Pleasanton, CA; Snyderman, Neal J [Berkeley, CA; Rowland, Mark S [Alamo, CA

    2012-05-15

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  15. Geographic Media Literacy

    Science.gov (United States)

    Lukinbeal, Chris

    2014-01-01

    While the use of media permeates geographic research and pedagogic practice, the underlying literacies that link geography and media remain uncharted. This article argues that geographic media literacy incorporates visual literacy, information technology literacy, information literacy, and media literacy. Geographic media literacy is the ability…

  16. Measuring News Media Literacy

    Science.gov (United States)

    Maksl, Adam; Ashley, Seth; Craft, Stephanie

    2015-01-01

    News media literacy refers to the knowledge and motivations needed to identify and engage with journalism. This study measured levels of news media literacy among 500 teenagers using a new scale measure based on Potter's model of media literacy and adapted to news media specifically. The adapted model posits that news media literate individuals…

  17. Handling of bulk solids theory and practice

    CERN Document Server

    Shamlou, P A

    1990-01-01

    Handling of Bulk Solids provides a comprehensive discussion of the field of solids flow and handling in the process industries. Presentation of the subject follows classical lines of separate discussions for each topic, so each chapter is self-contained and can be read on its own. Topics discussed include bulk solids flow and handling properties; pressure profiles in bulk solids storage vessels; the design of storage silos for reliable discharge of bulk materials; gravity flow of particulate materials from storage vessels; pneumatic transportation of bulk solids; and the hazards of solid-mater

  18. Transport of subsurface bacteria in porous media

    Energy Technology Data Exchange (ETDEWEB)

    Bales, R.C.; Arnold, R.G.; Gerba, C.P.

    1995-02-01

    The primary objective of this study was to develop tools with which to measure the advective transport of microorganisms through porous media. These tools were then applied to investigate the sorptive properties of representative microorganisms that were selected at random from the DOE`s deep subsurface collection of bacterial, maintained at Florida State University. The transport screening procedure that arose from this study was also used to investigate biological factors that affect the transport/sorption of biocolloids during their movement through porous media with the bulk advective flow.

  19. Nanofluidics, from bulk to interfaces.

    Science.gov (United States)

    Bocquet, Lydéric; Charlaix, Elisabeth

    2010-03-01

    Nanofluidics has emerged recently in the footsteps of microfluidics, following the quest for scale reduction inherent to nanotechnologies. By definition, nanofluidics explores transport phenomena of fluids at nanometer scales. Why is the nanometer scale specific? What fluid properties are probed at nanometric scales? In other words, why does 'nanofluidics' deserve its own brand name? In this critical review, we will explore the vast manifold of length scales emerging for fluid behavior at the nanoscale, as well as the associated mechanisms and corresponding applications. We will in particular explore the interplay between bulk and interface phenomena. The limit of validity of the continuum approaches will be discussed, as well as the numerous surface induced effects occurring at these scales, from hydrodynamic slippage to the various electro-kinetic phenomena originating from the couplings between hydrodynamics and electrostatics. An enlightening analogy between ion transport in nanochannels and transport in doped semi-conductors will be discussed (156 references).

  20. New fermions in the bulk

    CERN Document Server

    de Brito, K P S

    2016-01-01

    Spinor fields on 5-dimensional Lorentzian manifolds are classified, according to the geometric Fierz identities that involve their bilinear covariants. Based upon this classification that generalises the celebrated 4-dimensional Lounesto classification of spinor fields, new non-trivial classes of 5-dimensional spinor fields are, hence, found, with important potential applications regarding bulk fermions and their subsequent localisation on brane-worlds. In addition, quaternionic bilinear covariants are used to derive the quaternionic spin density, through the truncated exterior bundle. In order to accomplish a realisation of these new spinors, a Killing vector field is constructed on the horizon of 5-dimensional Kerr black holes. This Killing vector field is shown to reach the time-like Killing vector field at the spatial infinity, through a current 1-form density, constructed with the derived new spinor fields. The current density is, moreover, expressed as the f\\"unfbein components, assuming a condensed for...

  1. New fermions in the bulk

    Science.gov (United States)

    de Brito, K. P. S.; da Rocha, Roldão

    2016-10-01

    The spinor fields on 5-dimensional Lorentzian manifolds are classified according to the geometric Fierz identities, which involve their bilinear covariants. Based upon this classification, which generalises the celebrated 4-dimensional Lounesto classification of spinor fields, new non-trivial classes of 5-dimensional spinor fields are hence found, with important potential applications regarding bulk fermions and their subsequent localisation on brane-worlds. In addition, quaternionic bilinear covariants are used to derive the quaternionic spin density through the truncated exterior bundle. In order to accomplish the realisation of these new spinors, a Killing vector field is constructed on the horizon of a 5-dimensional Kerr black hole. This Killing vector field is shown to reach the time-like Killing vector field at spatial infinity through a current 1-form density, constructed with the new derived spinor fields. The current density is, moreover, expressed as the fünfbein component, assuming a condensed form.

  2. Antibiotic microbial assay using kinetic-reading microplate system

    OpenAIRE

    Felipe Rebello Lourenço; Terezinha de Jesus Andreoli Pinto

    2011-01-01

    The aim of this study was to determine the optimal experimental conditions to develop a methodology for microbiological assay of apramycin employing microplate and kinetic reading mode, and to validate the developed method, through evaluation of parameters of selectivity, linearity, linear range, limits of detection and quantification, accuracy and precision. The turbidimetric assay principle is simple: the test solution is added to a suspension of test microorganism in culture media, the mix...

  3. Predictive Assay For Cancer Targets

    Energy Technology Data Exchange (ETDEWEB)

    Suess, A; Nguyen, C; Sorensen, K; Montgomery, J; Souza, B; Kulp, K; Dugan, L; Christian, A

    2005-09-19

    Early detection of cancer is a key element in successful treatment of the disease. Understanding the particular type of cancer involved, its origins and probable course, is also important. PhIP (2-amino-1-methyl-6 phenylimidazo [4,5-b]pyridine), a heterocyclic amine produced during the cooking of meat at elevated temperatures, has been shown to induce mammary cancer in female, Sprague-Dawley rats. Tumors induced by PhIP have been shown to contain discreet cytogenetic signature patterns of gains and losses using comparative genomic hybridization (CGH). To determine if a protein signature exists for these tumors, we are analyzing expression levels of the protein products of the above-mentioned tumors in combination with a new bulk protein subtractive assay. This assay produces a panel of antibodies against proteins that are either on or off in the tumor. Hybridization of the antibody panel onto a 2-D gel of tumor or control protein will allow for identification of a distinct protein signature in the tumor. Analysis of several gene databases has identified a number of rat homologs of human cancer genes located in these regions of gain and loss. These genes include the oncogenes c-MYK, ERBB2/NEU, THRA and tumor suppressor genes EGR1 and HDAC3. The listed genes have been shown to be estrogen-responsive, suggesting a possible link between delivery of bio-activated PhIP to the cell nucleus via estrogen receptors and gene-specific PhIP-induced DNA damage, leading to cell transformation. All three tumors showed similar silver staining patterns compared to each other, while they all were different than the control tissue. Subsequent screening of these genes against those from tumors know to be caused by other agents may produce a protein signature unique to PhIP, which can be used as a diagnostic to augment optical and radiation-based detection schemes.

  4. Advertising on social media

    Directory of Open Access Journals (Sweden)

    Sumit Goyal

    2013-05-01

    Full Text Available This communication reports the latest trends of advertising on social media. Social media advertising means to gain traffic or attention of online users through social media sites. Today, when a user thinks about buying something, he first comes to the internet, searches for that product, compares its price with other competing brands and takes a decision, which one to buy. In this write-up, author has discussed many aspects concerning advertising through social media, viz., what is social media? What is the impact of social media on mainstream media, why to advertise on social media? and what should be the strategy for advertising on social media. The author is of the view that in the year 2013, $4 billion will be spent on social media advertising across the globe and social media industry will generate over 1,00,000 new jobs all around the world.

  5. Transgenic Animal Mutation Assays

    Institute of Scientific and Technical Information of China (English)

    Tao Chen; Ph.D.D.A.B.T.

    2005-01-01

    @@ The novel transgenic mouse and rat mutation assays have provided a tool for analyzing in vivo mutation in any tissue, thus permitting the direct comparison of cancer incidence with mutant frequency.

  6. Tube-Forming Assays.

    Science.gov (United States)

    Brown, Ryan M; Meah, Christopher J; Heath, Victoria L; Styles, Iain B; Bicknell, Roy

    2016-01-01

    Angiogenesis involves the generation of new blood vessels from the existing vasculature and is dependent on many growth factors and signaling events. In vivo angiogenesis is dynamic and complex, meaning assays are commonly utilized to explore specific targets for research into this area. Tube-forming assays offer an excellent overview of the molecular processes in angiogenesis. The Matrigel tube forming assay is a simple-to-implement but powerful tool for identifying biomolecules involved in angiogenesis. A detailed experimental protocol on the implementation of the assay is described in conjunction with an in-depth review of methods that can be applied to the analysis of the tube formation. In addition, an ImageJ plug-in is presented which allows automatic quantification of tube images reducing analysis times while removing user bias and subjectivity.

  7. Cell viability assays: introduction.

    Science.gov (United States)

    Stoddart, Martin J

    2011-01-01

    The measurement of cell viability plays a fundamental role in all forms of cell culture. Sometimes it is the main purpose of the experiment, such as in toxicity assays. Alternatively, cell viability can be used to -correlate cell behaviour to cell number, providing a more accurate picture of, for example, anabolic -activity. There are wide arrays of cell viability methods which range from the most routine trypan blue dye exclusion assay to highly complex analysis of individual cells, such as using RAMAN microscopy. The cost, speed, and complexity of equipment required will all play a role in determining the assay used. This chapter aims to provide an overview of many of the assays available today.

  8. New Rapid Spore Assay

    Science.gov (United States)

    Kminek, Gerhard; Conley, Catharine

    2012-07-01

    The presentation will detail approved Planetary Protection specifications for the Rapid Spore Assay for spacecraft components and subsystems. Outlined will be the research and studies on which the specifications were based. The research, funded by ESA and NASA/JPL, was conducted over a period of two years and was followed by limited cleanroom studies to assess the feasibility of this assay during spacecraft assembly.

  9. Coupling brane fields to bulk supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Parameswaran, Susha L. [Uppsala Univ. (Sweden). Theoretical Physics; Schmidt, Jonas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2010-12-15

    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  10. Relative entropy equals bulk relative entropy

    CERN Document Server

    Jafferis, Daniel L; Maldacena, Juan; Suh, S Josephine

    2015-01-01

    We consider the gravity dual of the modular Hamiltonian associated to a general subregion of a boundary theory. We use it to argue that the relative entropy of nearby states is given by the relative entropy in the bulk, to leading order in the bulk gravitational coupling. We also argue that the boundary modular flow is dual to the bulk modular flow in the entanglement wedge, with implications for entanglement wedge reconstruction.

  11. Why Media Matter

    Science.gov (United States)

    Locatis, Craig

    2007-01-01

    Whether media affect learning has been debated for decades. The discussion of media's effectiveness has raised questions about the usefulness of comparison studies, not only in assessing applications of technology but in other areas as well. Arguments that media do not affect learning are re-examined and issues concerning media effects on expert…

  12. Media Violence and Children.

    Science.gov (United States)

    Groebel, Jo

    1998-01-01

    Presents the results of the UNESCO global study on media violence and children which was conducted between 1996 and 1997. Highlights include the role of the media, media heroes as role models, media violence and aggression, differences by gender, rural versus urban environments, the pervasiveness of television, and recommendations. (Author/LRW)

  13. Fusion arrest and collapse phenomena due to Kerr-nonlinearity in quadratic media

    DEFF Research Database (Denmark)

    Johansen, Steffen Kjær; Bang, Ole; Sørensen, Mads Peter

    2000-01-01

    Emphasizing collapse phenomena it is investigated to what extend the always present cubic nonlinearity affects the properties of soliton interaction in quadratic bulk media. An effective particle approach is applied and verified by numerical simulations.......Emphasizing collapse phenomena it is investigated to what extend the always present cubic nonlinearity affects the properties of soliton interaction in quadratic bulk media. An effective particle approach is applied and verified by numerical simulations....

  14. 33 CFR 127.313 - Bulk storage.

    Science.gov (United States)

    2010-07-01

    ...) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Operations § 127.313 Bulk storage. (a) The...

  15. Applications of bulk high-temperature superconductors

    Science.gov (United States)

    Hull, J. R.

    The development of high-temperature superconductors (HTS's) can be broadly generalized into thin-film electronics, wire applications, and bulk applications. We consider bulk HTS's to include sintered or crystallized forms that do not take the geometry of filaments or tapes, and we discuss major applications for these materials. For the most part applications may be realized with the HTS's cooled to 77 K, and the properties of the bulk HTS's are often already sufficient for commercial use. A non-exhaustive list of applications for bulk HTS's includes trapped field magnets, hysteresis motors, magnetic shielding, current leads, and magnetic bearings. These applications are briefly discussed in this paper.

  16. Understanding social media logic

    OpenAIRE

    José van Dijck; Thomas Poell

    2013-01-01

    Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions and rules of social interaction. In this article, we examine the intricate dynamic between social media platforms, mass media, users, and social institutions by calling attention to social media lo...

  17. Social media influencer marketing

    OpenAIRE

    Isosuo, Heli

    2016-01-01

    The marketing field is changing simultaneously with the digital world. Social media is getting more and more important to marketers, and there is a need to stand out in the social media noise. Social media influencer marketing could be a good alternative to other types of marketing. A need from the consignor and the interest of the author were the motivations for conducting the study. Sääskilahti Consulting has a social media influencer network Somevaikuttajat, which is offering social media ...

  18. Testing of bulk tank milk for Salmonella Dublin infection in Danish dairy herds

    DEFF Research Database (Denmark)

    Wedderkopp, A.; Stroger, U.; Bitsch, V.;

    2001-01-01

    of being test-negative in the third test round was 0.926 for a herd with 2 previous test-negative results. It was concluded that the investigated ELISA method was in general accordance with the cases of clinical S. Dublin infection recorded. and that the method has a potential for national screening......The usefulness of enzyme-linked immunosorbent assay (ELISA) was investigated as a simple method to screen for Salmonella Dublin infection in dairy herds, examining bulk tank milk samples for lipopolysaccharide (O:1,9,12) antibodies. The cut-off value for the ELISA on bulk tank milk was established...... based on individual milk samples (n = 2887) and bulk tank milk from 52 herds. Bulk tank milk samples (n = 5108) were collected from 1464 dairy herds located in 19 different areas. About 10% of the dairy herds in Denmark participated in the study. The percentage of herds changing from test...

  19. Against vaccine assay secrecy.

    Science.gov (United States)

    Herder, Matthew; Hatchette, Todd F; Halperin, Scott A; Langley, Joanne M

    2015-01-01

    Increasing the transparency of the evidence base behind health interventions such as pharmaceuticals, biologics, and medical devices, has become a major point of critique, conflict, and policy focus in recent years. Yet the lack of publicly available information regarding the immunogenicity assays upon which many important, widely used vaccines are based has received no attention to date. In this paper we draw attention to this critical public health problem by reporting on our efforts to secure vaccine assay information in respect of 10 vaccines through Canada's access to information law. We argue, under Canadian law, that the public health interest in having access to the methods for these laboratory procedures should override claims by vaccine manufacturers and regulators that this information is proprietary; and, we call upon several actors to take steps to ensure greater transparency with respect to vaccine assays, including regulators, private firms, researchers, research institutions, research funders, and journal editors.

  20. Against vaccine assay secrecy

    Science.gov (United States)

    Herder, Matthew; Hatchette, Todd F; Halperin, Scott A; Langley, Joanne M

    2015-01-01

    Increasing the transparency of the evidence base behind health interventions such as pharmaceuticals, biologics, and medical devices, has become a major point of critique, conflict, and policy focus in recent years. Yet the lack of publicly available information regarding the immunogenicity assays upon which many important, widely used vaccines are based has received no attention to date. In this paper we draw attention to this critical public health problem by reporting on our efforts to secure vaccine assay information in respect of 10 vaccines through Canada's access to information law. We argue, under Canadian law, that the public health interest in having access to the methods for these laboratory procedures should override claims by vaccine manufacturers and regulators that this information is proprietary; and, we call upon several actors to take steps to ensure greater transparency with respect to vaccine assays, including regulators, private firms, researchers, research institutions, research funders, and journal editors. PMID:25826194

  1. Rover waste assay system

    Energy Technology Data Exchange (ETDEWEB)

    Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1997-11-01

    The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched {sup 235}U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for {sup 137}Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs.

  2. Bulk amorphous Mg-based alloys

    DEFF Research Database (Denmark)

    Pryds, Nini

    2004-01-01

    The present paper describes the preparation and properties of bulk amorphous quarternary Mg-based alloys and the influence of additional elements on the ability of the alloy to form bulk amorphous. The main goal is to find a Mg-based alloy system which shows both high strength to weight ratio and...

  3. 27 CFR 20.191 - Bulk articles.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk articles. 20.191... Users of Specially Denatured Spirits Operations by Users § 20.191 Bulk articles. Users who convey articles in containers exceeding one gallon may provide the recipient with a photocopy of subpart G of...

  4. Assays for calcitonin receptors

    Energy Technology Data Exchange (ETDEWEB)

    Teitelbaum, A.P.; Nissenson, R.A.; Arnaud, C.D.

    1985-01-01

    The assays for calcitonin receptors described focus on their use in the study of the well-established target organs for calcitonin, bone and kidney. The radioligand used in virtually all calcitonin binding studies is /sup 125/I-labelled salmon calcitonin. The lack of methionine residues in this peptide permits the use of chloramine-T for the iodination reaction. Binding assays are described for intact bone, skeletal plasma membranes, renal plasma membranes, and primary kidney cell cultures of rats. Studies on calcitonin metabolism in laboratory animals and regulation of calcitonin receptors are reviewed.

  5. CTL ELISPOT assay.

    Science.gov (United States)

    Ranieri, Elena; Popescu, Iulia; Gigante, Margherita

    2014-01-01

    Enzyme-linked immune absorbent spot (Elispot) is a quantitative method for measuring relevant parameters of T cell activation. The sensitivity of Elispot allows the detection of low-frequency antigen-specific T cells that secrete cytokines and effector molecules, such as granzyme B and perforin. Cytotoxic T cell (CTL) studies have taken advantage with this high-throughput technology by providing insights into quantity and immune kinetics. Accuracy, sensitivity, reproducibility, and robustness of Elispot resulted in a wide range of applications in research as well as in diagnostic field. Actually, CTL monitoring by Elispot is a gold standard for the evaluation of antigen-specific T cell immunity in clinical trials and vaccine candidates where the ability to detect rare antigen-specific T cells is of relevance for immune diagnostic. The most utilized Elispot assay is the interferon-gamma (IFN-γ) test, a marker for CD8(+) CTL activation, but Elispot can also be used to distinguish different subsets of activated T cells by using other cytokines such as T-helper (Th) 1-type cells (characterized by the production of IFN-γ, IL-2, IL-6, IL-12, IL-21, and TNF-α), Th2 (producing cytokines like IL-4, IL-5, IL-10, and IL-13), and Th17 (IL-17) cells. The reliability of Elispot-generated data, by the evaluation of T cell frequency recognizing individual antigen/peptide, is the core of this method currently applied widely to investigate specific immune responses in cancer, infections, allergies, and autoimmune diseases. The Elispot assay is competing with other methods measuring single-cell cytokine production, e.g., intracellular cytokine by FACS or Miltenyi cytokine secretion assay. Other types of lymphocyte frequency and function assays include limiting dilution assay (LDA), cytotoxic T cell assay (CTL), and tetramer staining. Compared with respect to sensitivity the Elispot assay is outranking other methods to define frequency of antigen-specific lymphocytes. The method

  6. Unpacking New Media Literacy

    Directory of Open Access Journals (Sweden)

    Der-Thanq “victor” Chen

    2011-04-01

    Full Text Available The 21st century has marked an unprecedented advancement of new media. New media has become so pervasive that it has penetrated into every aspect of our society. New media literacy plays an essential role for any citizen to participate fully in the 21st century society. Researchers have documented that literacy has evolved historically from classic literacy (reading-writing-understanding to audiovisual literacy to digital literacy or information literacy and recently to new media literacy. A review of literature on media literacy reveals that there is a lack of thorough analysis of unique characteristics of new media and its impacts upon the notion of new media literacy. The purpose of the study is to unpack new media literacy and propose a framework for a systematic investigation of new media literacy.

  7. Media Pluralism and Diversity

    DEFF Research Database (Denmark)

    challenges for media pluralism policies in the light of a fast changing media environment. The book is unique in that it confronts insights from all parts of the world and from a broad range of disciplines including law, economics, media studies, and sociology.......In the western world, a diverse and pluralistic media landscape is deemed essential for democracy. But how universal is media pluralism as a concept underpinning media policies? To what extent do normative approaches, regulatory dimensions and monitoring systems differ throughout the world......? Adopting a truly global, theoretical and multidisciplinary perspective, Media Pluralism and Diversity advances our understanding of media pluralism across the globe. It compares metrics developed in different parts of the world to assess levels of, or threats to, media pluralism. It identifies common...

  8. Instrument for assaying radiation

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Jody Rustyn; Farfan, Eduardo B.

    2016-03-22

    An instrument for assaying radiation includes a flat panel detector having a first side opposed to a second side. A collimated aperture covers at least a portion of the first side of the flat panel detector. At least one of a display screen or a radiation shield may cover at least a portion of the second side of the flat panel detector.

  9. New oligosaccharyltransferase assay method.

    Science.gov (United States)

    Kohda, Daisuke; Yamada, Masaki; Igura, Mayumi; Kamishikiryo, Jun; Maenaka, Katsumi

    2007-11-01

    We developed a new in vitro assay for oligosaccharyltransferase (OST), which catalyzes the transfer of preassembled oligosaccharides on lipid carriers onto asparagine residues in polypeptide chains. The asparagine residues reside in the sequon, Asn-X-Thr/Ser, where X can be any amino acid residue except Pro. We demonstrate the potency of our assay using the OST from yeast. In our method, polyacrylamide gel electrophoresis is used to separate the glycopeptide products from the peptide substrates. The substrate peptide is fluorescently labeled and the formation of glycopeptides is analyzed by fluorescence gel imaging. Two in vitro OST assay methods are now widely used, but both the methods depend on previous knowledge of the oligosaccharide moiety: One method uses lectin binding as the separation mechanism and the other method uses biosynthetically or chemoenzymatically synthesized lipid-linked oligosaccharides as donors. N-linked protein glycosylation is found in all three domains of life, but little is known about the N-glycosylation in Archaea. Thus, our new assay, which does not require a priori knowledge of the oligosaccharides, will be useful in such cases. Indeed, we have detected the OST activity in the membrane fraction from a hyperthermophilic archaeon, Pyrococcus furiosus.

  10. Hyaluronic Acid Assays

    DEFF Research Database (Denmark)

    Itenov, Theis S; Kirkby, Nikolai S; Bestle, Morten H

    2015-01-01

    BACKGROUD: Hyaluronic acid (HA) is proposed as a marker of functional liver capacity. The aim of the present study was to compare a new turbidimetric assay for measuring HA with the current standard method. METHODS: HA was measured by a particle-enhanced turbidimetric immunoassay (PETIA) and enzyme...

  11. Social Media Reputation

    DEFF Research Database (Denmark)

    Etter, Michael Andreas; Ravasi, Davide; Colleoni, Elanor

    Social media enable millions of users to create and disseminate narratives about organizations that increase their public exposure and shape public perceptions. In this paper, we draw on the sociology of news production and research on computer-mediated communication to discuss how different...... motivational drivers and contextual conditions associated with the formation of narratives in traditional news media and social media influence their content, diffusion, and impact significantly. Our analysis suggests that current theories of media reputation may provide an incomplete representation...... of the phenomenon, and highlight theoretically relevant differences and interrelationships between reputational dynamics involving news media and social media....

  12. Signed Networks in Social Media

    CERN Document Server

    Leskovec, Jure; Kleinberg, Jon

    2010-01-01

    Relations between users on social media sites often reflect a mixture of positive (friendly) and negative (antagonistic) interactions. In contrast to the bulk of research on social networks that has focused almost exclusively on positive interpretations of links between people, we study how the interplay between positive and negative relationships affects the structure of on-line social networks. We connect our analyses to theories of signed networks from social psychology. We find that the classical theory of structural balance tends to capture certain common patterns of interaction, but that it is also at odds with some of the fundamental phenomena we observe --- particularly related to the evolving, directed nature of these on-line networks. We then develop an alternate theory of status that better explains the observed edge signs and provides insights into the underlying social mechanisms. Our work provides one of the first large-scale evaluations of theories of signed networks using on-line datasets, as ...

  13. Turkish Media Elites

    Directory of Open Access Journals (Sweden)

    D. Ali Arslan

    2008-07-01

    Full Text Available The media is one of the most important institutions in society. It is a reality that media play very substantial role in the production and social distribution of knowledge. In addition to that, mass media provides the greatest communication opportunities to the people. Also, contemporary media provides very distinctive weapons to obtain power, wealth and prestige in the society. If media owners and elites are so powerful, the identification of media elites is of great importance. Hence, this study aims to analyse contemporary Turkish media: A full picture of Turkish media elites in terms of important social, political and demographic indicators will be given in this paper. The managers, editors, influential columnists and reporters of major Turkish media elites are defined as Turkish media elites. Firstly, the paper will focuse on the demographic peculiarities of Turkish media elites. Secondly, the educational background and family structure of Turkish media elites will be examined. Then, social origins and other social characteristics of Contemporary Turkish media elites will be investigated.

  14. AMAMM - All Media Are Mixed Media

    DEFF Research Database (Denmark)

    All Media Are Mixed Media Alle medier er blandingsmedier. Alle kunstarter er kompositte. Alle sanser er sammensatte. Alle medialiteter er miksede og mangfoldige. Alle er AMAMM. Denne påstand står centralt i ord-, billed- og medie-teoretikeren W.J.T. Mitchells forfatterskab. I hosstående bog tager...

  15. Amalgamation of interacting light beamlets in Kerr-type media

    DEFF Research Database (Denmark)

    Christiansen, Peter Leth; Rasmussen, Kim; Berge, L;

    1997-01-01

    The interaction of optical filaments in bulk self-focusing media is investigated theoretically and numerically. The nature of this interaction is shown to vary with the incident individual powers and relative phases of the beamlets. By means of virial arguments supported by numerical results it i...

  16. Media and Crime

    DEFF Research Database (Denmark)

    Agger, Gunhild; Waade, Anne Marit

    2011-01-01

    Recent developments in the relationship between media and crime are analyzed, taking both fiction and journalism in account......Recent developments in the relationship between media and crime are analyzed, taking both fiction and journalism in account...

  17. Sociale media als leermiddel

    NARCIS (Netherlands)

    Rubens, Wilfred

    2012-01-01

    Rubens, W. (2012, 5 juni). Sociale media als leermiddel. Presentatie over het gebruik van sociale media binnen het onderwijs, verzorgd tijdens een ouderraadbijeenkomst van de Katholieke Scholengemeenschap Etten-Leur, Etten-Leur, Nederland.

  18. MODERN MEDIA EDUCATION MODELS

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2011-03-01

    Full Text Available The author supposed that media education models can be divided into the following groups:- educational-information models (the study of the theory, history, language of media culture, etc., based on the cultural, aesthetic, semiotic, socio-cultural theories of media education;- educational-ethical models (the study of moral, religions, philosophical problems relying on the ethic, religious, ideological, ecological, protectionist theories of media education;- pragmatic models (practical media technology training, based on the uses and gratifications and ‘practical’ theories of media education;- aesthetical models (aimed above all at the development of the artistic taste and enriching the skills of analysis of the best media culture examples. Relies on the aesthetical (art and cultural studies theory; - socio-cultural models (socio-cultural development of a creative personality as to the perception, imagination, visual memory, interpretation analysis, autonomic critical thinking, relying on the cultural studies, semiotic, ethic models of media education.

  19. Automating the Media Center.

    Science.gov (United States)

    Holloway, Mary A.

    1988-01-01

    Discusses the need to develop more efficient information retrieval skills by the use of new technology. Lists four stages used in automating the media center. Describes North Carolina's pilot programs. Proposes benefits and looks at the media center's future. (MVL)

  20. Trends in media use.

    Science.gov (United States)

    Roberts, Donald F; Foehr, Ulla G

    2008-01-01

    American youth are awash in media. They have television sets in their bedrooms, personal computers in their family rooms, and digital music players and cell phones in their backpacks. They spend more time with media than any single activity other than sleeping, with the average American eight- to eighteen-year-old reporting more than six hours of daily media use. The growing phenomenon of "media multitasking"--using several media concurrently--multiplies that figure to eight and a half hours of media exposure daily. Donald Roberts and Ulla Foehr examine how both media use and media exposure vary with demographic factors such as age, race and ethnicity, and household socioeconomic status, and with psychosocial variables such as academic performance and personal adjustment. They note that media exposure begins early, increases until children begin school, drops off briefly, then climbs again to peak at almost eight hours daily among eleven- and twelve-year-olds. Television and video exposure is particularly high among African American youth. Media exposure is negatively related to indicators of socioeconomic status, but that relationship may be diminishing. Media exposure is positively related to risk-taking behaviors and is negatively related to personal adjustment and school performance. Roberts and Foehr also review evidence pointing to the existence of a digital divide--variations in access to personal computers and allied technologies by socioeconomic status and by race and ethnicity. The authors also examine how the recent emergence of digital media such as personal computers, video game consoles, and portable music players, as well as the media multitasking phenomenon they facilitate, has increased young people's exposure to media messages while leaving media use time largely unchanged. Newer media, they point out, are not displacing older media but are being used in concert with them. The authors note which young people are more or less likely to use several

  1. Managing social media conversations

    OpenAIRE

    2015-01-01

    The purpose of this thesis was to explore how companies can manage (monitor and control) social media conversations. Regardless of the companies’ presence in social media networks, they or their industry are constantly being discussed in social media. Therefore organisations should be present in social media, monitor and participate in conversations, in order to turn them into their benefit. There are software and services available to help in monitoring. Variety of tools and statistic de...

  2. The social media image

    OpenAIRE

    2014-01-01

    How do the organization and presentation of large-scale social media images recondition the process by which visual knowledge, value, and meaning are made in contemporary conditions? Analyzing fundamental elements in the changing syntax of existing visual software ontology—the ways current social media platforms and aggregators organize and categorize social media images—this article relates how visual materials created within social media platforms manifest distinct modes of knowledge produc...

  3. Children and the Media

    OpenAIRE

    Dennis, Everette E.; Pease, Edward C.

    1996-01-01

    Throughout history the media has primarily been produced by adults, for adults, about adults. Increasingly, children have become a matter of high priority in the modern media society, and as they have, they have also become the subject of much concern. From debates in Congress about the detrimental effects of movies, comic books, and video games over the last century to efforts to court children as media consumers, there is a clear recognition that the media are not now and probably ne...

  4. Advertising on social media

    OpenAIRE

    Sumit Goyal

    2013-01-01

    This communication reports the latest trends of advertising on social media. Social media advertising means to gain traffic or attention of online users through social media sites. Today, when a user thinks about buying something, he first comes to the internet, searches for that product, compares its price with other competing brands and takes a decision, which one to buy. In this write-up, author has discussed many aspects concerning advertising through social media, viz., what is social me...

  5. High output power electric motors with bulk HTS elements

    Science.gov (United States)

    Kovalev, L. K.; Ilushin, K. V.; Kovalev, K. L.; Penkin, V. T.; Poltavets, V. N.; Koneev, S. M.-A.; Akimov, I. I.; Gawalek, W.; Oswald, B.; Krabbes, G.

    2003-04-01

    New types of electric machines with the rotors containing bulk HTS (YBCO and Bi-Ag) elements are presented. Different schematics of hysteresis, reluctance, “trapped field” and composed synchronous HTS machines are discussed. The two-dimensional mathematical models describing the processes in such types of HTS machines were developed on the basis of the theoretical analysis of the electrodynamic and hysteresis processes in the single-domain and polycrystal YBCO ceramic samples and plate shape Bi-Ag elements. The test results of the series of hysteresis, reluctance, “trapped field” and composed with permanent magnets HTS motors with output power rating 0.1-18 kW and current frequency 50 and 400 Hz are given. These results show that in the media of liquid nitrogen the specific output power per one weight unit of HTS motors is 4-7 times better than for conventional electric machines. Comparison of the theoretical and experimental characteristics of the developed HTS motors show that they are in good agreement. The test results for liquid nitrogen cryogenic pump system with hysteresis 500 W HTS motor are discussed. The designs and first test results of HTS motor operating in the media of liquid nitrogen with output power 100 kW and power factor more than 0.8 are given. Future development and applications of new types of HTS motors for aerospace technology, on-land industry and transport systems are discussed.

  6. Kinetic Tetrazolium Microtiter Assay

    Science.gov (United States)

    Pierson, Duane L.; Stowe, Raymond; Koenig, David

    1993-01-01

    Kinetic tetrazolium microtiter assay (KTMA) involves use of tetrazolium salts and Triton X-100 (or equivalent), nontoxic, in vitro color developer solubilizing colored metabolite formazan without injuring or killing metabolizing cells. Provides for continuous measurement of metabolism and makes possible to determine rate of action of antimicrobial agent in real time as well as determines effective inhibitory concentrations. Used to monitor growth after addition of stimulatory compounds. Provides for kinetic determination of efficacy of biocide, greatly increasing reliability and precision of results. Also used to determine relative effectiveness of antimicrobial agent as function of time. Capability of generating results on day of test extremely important in treatment of water and waste, disinfection of hospital rooms, and in pharmaceutical, agricultural, and food-processing industries. Assay also used in many aspects of cell biology.

  7. The corneal pocket assay.

    Science.gov (United States)

    Ziche, Marina; Morbidelli, Lucia

    2015-01-01

    The cornea in most species is physiologically avascular, and thus this assay allows the measurement of newly formed vessels. The continuous monitoring of neovascular growth in the same animal allows the evaluation of drugs acting as suppressors or stimulators of angiogenesis. Under anesthesia a micropocket is produced in the cornea thickness and the angiogenesis stimulus (tumor tissue, cell suspension, growth factor) is placed into the pocket in order to induce vascular outgrowth from the limbal capillaries. Neovascular development and progression can be modified by the presence of locally released or applied inhibitory factors or by systemic treatments. In this chapter the experimental details of the avascular cornea assay, the technical challenges, and advantages and disadvantages in different species are discussed. Protocols for local drug treatment and tissue sampling for histology and pharmacokinetic profile are reported.

  8. Children's Media Policy

    Science.gov (United States)

    Jordan, Amy B.

    2008-01-01

    Amy Jordan addresses the need to balance the media industry's potentially important contributions to the healthy development of America's children against the consequences of excessive and age-inappropriate media exposure. Much of the philosophical tension regarding how much say the government should have about media content and delivery stems…

  9. Teenagers Media Habits.

    Science.gov (United States)

    Campbell, Laurence R.

    This study attempted to determine what media most effectively communicated to teenagers, how the media habits of Florida teenagers compared with those in other states, and how the media habits of journalism students compared with those not in journalism. A total of 430 students from Florida high schools and 457 from high schools in other states…

  10. Youth Media and Agency

    Science.gov (United States)

    Hauge, Chelsey

    2014-01-01

    This article addresses how capacity is conceived of and understood in youth media/civic education programming, and how beliefs about agency, development, relationality and youth manifests in the discourses, programmes, and practices of organizations operating youth media programmes. Through attention to a youth media and development programme in…

  11. Media, Minds, and Masses.

    Science.gov (United States)

    Baggot, James; Vino, Faith

    This booklet describes the language arts course "Media, Minds, and Masses," written for the Dade County, Fla., public schools. Topics for the course include the workings of contemporary radio, television, newspapers, magazines, and movies; the present status and power of media; the history and development of media; and the influences of…

  12. Managing Media Workers

    NARCIS (Netherlands)

    M. Deuze

    2015-01-01

    People are more involved with media than ever but news about media as an industry is less than optimistic. The number of people across the creative industries who are losing jobs illustrates all too well. Media managers seem at a loss in developing survival strategies, and specifically in organizing

  13. News Media Industry

    Science.gov (United States)

    2007-01-01

    absence of a democratic media law and the lasting power monopoly of the state owned media on the other hand (Myagmar, 2000). First, legal basis of...implementation. The censorship authority was abolished already in 1989, but it was not until the 1998 media law that censorship was prohibited

  14. Modern Media Education Models

    Science.gov (United States)

    Fedorov, Alexander

    2011-01-01

    The author supposed that media education models can be divided into the following groups: (1) educational-information models (the study of the theory, history, language of media culture, etc.), based on the cultural, aesthetic, semiotic, socio-cultural theories of media education; (2) educational-ethical models (the study of moral, religions,…

  15. Mapping digital media: Netherlands

    NARCIS (Netherlands)

    de Waal, M.; Leurdijk, A.; Nordeman, L.; Poell, T.

    2012-01-01

    The Mapping Digital Media project examines the global opportunities and risks created by the transition from traditional to digital media. Covering 60 countries, the project examines how these changes affect the core democratic service that any media system should provide: news about political, econ

  16. B cell helper assays.

    Science.gov (United States)

    Abrignani, Sergio; Tonti, Elena; Casorati, Giulia; Dellabona, Paolo

    2009-01-01

    Activation, proliferation and differentiation of naïve B lymphocytes into memory B cells and plasma cells requires engagement of the B cell receptor (BCR) coupled to T-cell help (1, 2). T cells deliver help in cognate fashion when they are activated upon recognition of specific MHC-peptide complexes presented by B cells. T cells can also deliver help in a non-cognate or bystander fashion, when they do not find specific MHC-peptide complexes on B cells and are activated by alternative mechanisms. T-cell dependent activation of B cells can be studied in vitro by experimental models called "B cell helper assays" that are based on the co-culture of B cells with activated T cells. These assays allow to decipher the molecular bases for productive T-dependent B cell responses. We show here examples of B cell helper assays in vitro, which can be reproduced with any subset of T lymphocytes that displays the appropriate helper signals.

  17. Superconducting bulk magnets for magnetic levitation systems

    Science.gov (United States)

    Fujimoto, H.; Kamijo, H.

    2000-06-01

    The major applications of high-temperature superconductors have mostly been confined to products in the form of wires and thin films. However, recent developments show that rare-earth REBa 2Cu 3O 7- x and light rare-earth LREBa 2Cu 3O 7- x superconductors prepared by melt processes have a high critical-current density at 77 K and high magnetic fields. These superconductors will promote the application of bulk high-temperature superconductors in high magnetic fields; the superconducting bulk magnet for the Maglev train is one possible application. We investigated the possibility of using bulk magnets in the Maglev system, and examined flux-trapping characteristics of multi-superconducting bulks arranged in array.

  18. Measuring Bulk Flows in Large Scale Surveys

    CERN Document Server

    Feldman, H A; Feldman, Hume A.; Watkins, Richard

    1993-01-01

    We follow a formalism presented by Kaiser to calculate the variance of bulk flows in large scale surveys. We apply the formalism to a mock survey of Abell clusters \\'a la Lauer \\& Postman and find the variance in the expected bulk velocities in a universe with CDM, MDM and IRAS--QDOT power spectra. We calculate the velocity variance as a function of the 1--D velocity dispersion of the clusters and the size of the survey.

  19. Prospects for Detecting a Cosmic Bulk Flow

    Science.gov (United States)

    Rose, Benjamin; Garnavich, Peter M.; Mathews, Grant James

    2015-01-01

    The ΛCDM model is based upon a homogeneous, isotropic space-time leading to uniform expansion with random peculiar velocities caused by local gravitation perturbations. The Cosmic Microwave Background (CMB) radiation evidences a significant dipole moment in the frame of the Local Group. This motion is usually explained with the Local Group's motion relative to the background Hubble expansion. An alternative explanation, however, is that the dipole moment is the result of horizon-scale curvature remaining from the birth of space-time, possibly a result of quantum entanglement with another universe. This would appear as a single velocity (a bulk flow) added to all points in space. These two explanations differ observationally on cosmic distance scales (z > 0.1). There have been many differing attempts to detect a bulk flow, many with no detectable bulk flow but some with a bulk flow velocity as large as 1000 km/s. Here we report on a technique based upon minimizing the scatter around the expected cosine distribution of the Hubble redshift residuals with respect to angular distance on the sky. That is, the algorithm searches for a directional dependence of Hubble residuals. We find results consistent with most other bulk flow detections at z Type Ia Supernovae to be ~0.01, whereas the current error (~0.2.) is more than an order of magnitude too large for the detection of bulk flow beyond z~0.05.

  20. Oriented Fiber Filter Media

    Directory of Open Access Journals (Sweden)

    R. Bharadwaj

    2008-06-01

    Full Text Available Coalescing filters are widely used throughout industry and improved performance will reduce droplet emissions and operating costs. Experimental observations show orientation of micro fibers in filter media effect the permeability and the separation efficiency of the filter media. In this work two methods are used to align the fibers to alter the filter structure. The results show that axially aligned fiber media improve quality factor on the order of 20% and cutting media on an angle from a thick layered media can improve performance by about 40%. The results also show the improved performance is not monotonically correlated to the average fiber angle of the medium.

  1. Prosocial effects of media.

    Science.gov (United States)

    Hogan, Marjorie J

    2012-06-01

    Parents, teachers, health care providers, and other caring adults worry about the harmful influence of media messages and images on children and teens and wonder how to recognize and encourage positive and healthy use of media. For decades, experts have commented on the power of media. Media depictions can lead to negative attitudes and behavior in some young viewers. This article discusses whether prosocial, tolerant, and cooperative attitudes and behavior can be learned and imitated by children and adolescents and whether media can nurture or stimulate creativity or actively promote health and well-being in young consumers.

  2. Asian Media Productions

    DEFF Research Database (Denmark)

    This work consists of 12 essays on different aspects of Asian media by Japanese, European, and American scholars, many of whom have themselves been involved in the production of media forms. Working in the fields of anthropology, media and cultural studies, and on the basis of hands-on research, ......, they have written a book on the social practices and cultural attitudes of people producing, reading, watching and listening to different kinds of media in Japan, China, Taiwan, Indonesia, Vietnam, Singapore and India.......This work consists of 12 essays on different aspects of Asian media by Japanese, European, and American scholars, many of whom have themselves been involved in the production of media forms. Working in the fields of anthropology, media and cultural studies, and on the basis of hands-on research...

  3. Comprehension of digital media

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ju Hwan

    2008-11-15

    This book is divided four parts. The first part describes media and mark on sign and media, what is the sign?, interpretation of sign and semiotics. The second part is for production sign theory and origin of digital revolution such as the problem of origin of digital revolution, homogeneity of producing goods and sign : triple triangle model for production sign theory, triple triangle model for producing goods, triple triangle model of producing sign and triple triangle model of art works. The third parts deals with development of the media and meaning of digital revolution with four changes : invention of letter, appearance of printed media and establishment modernity, appearance electronic media and mess media and appearance of digital media. The last part mentions ontology of world wide web.

  4. The Media Mixer

    DEFF Research Database (Denmark)

    Vestergaard, Vitus; Mortensen, Christian Hviid

    2011-01-01

    throughout the Internet, most notably on web 2.0 sites like YouTube. The Media Museum has embraced the remix paradigm with the development of an interactive media experience centre called the Media Mixer. Here the museum users can produce, deconstruct, reconstruct and finally publish and share digital media......We explore how remixing and content sharing can be used as a means for user participation in a digital museum age. Remix culture is seen as a culture that allows and encourages the production of derivative works; works that are based on already existing works. This cultural practice thrives...... content. The media content is created by the user in the museum's physical environment, but it can be mixed with material from web archives. It is the intention that the users learn about media through participatory and creative processes with media where the borders between producing, playing...

  5. Understanding Social Media Logic

    Directory of Open Access Journals (Sweden)

    José van Dijck

    2013-08-01

    Full Text Available Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions and rules of social interaction. In this article, we examine the intricate dynamic between social media platforms, mass media, users, and social institutions by calling attention to social media logic—the norms, strategies, mechanisms, and economies—underpin­ning its dynamics. This logic will be considered in light of what has been identified as mass me­dia logic, which has helped spread the media's powerful discourse outside its institutional boundaries. Theorizing social media logic, we identify four grounding principles—programmabil­ity, popularity, connectivity, and datafication—and argue that these principles become increas­ingly entangled with mass media logic. The logic of social media, rooted in these grounding principles and strategies, is gradually invading all areas of public life. Besides print news and broadcasting, it also affects law and order, social activism, politics, and so forth. Therefore, its sustaining logic and widespread dissemination deserve to be scrutinized in detail in order to better understand its impact in various domains. Concentrating on the tactics and strategies at work in social media logic, we reassess the constellation of power relationships in which social practices unfold, raising questions such as: How does social media logic modify or enhance ex­isting mass media logic? And how is this new media logic exported beyond the boundaries of (social or mass media proper? The underlying principles, tactics, and strategies may be relat­ively simple to identify, but it is much harder to map the complex connections between plat­forms that distribute this logic: users that employ them, technologies that

  6. Influences of acidic conditions on formazan assay: a cautionary note.

    Science.gov (United States)

    Johno, Hisashi; Takahashi, Shuhei; Kitamura, Masanori

    2010-11-01

    Formazan assay has been used for several decades to evaluate metabolic activity of eukaryotic and prokaryotic cells. In particular, it has been often applied for quantitative assessment of viable cells under acidic circumstances caused by, e.g., ischemia and hypoxia. However, little attention has been paid to the influence of acidic pH on formazan assays. We found that acidic culture conditions significantly affect outcomes of the assays. Absorbance of tetrazolium-formazan decreased in a pH-dependent manner without affecting cell viability. This nonspecific effect was ascribed to influences of acidic pH on the production of formazan. Replacement of culture media to fresh medium at physiologic pH partially overcame this problem. The influence of acidic culture conditions should be carefully considered when formazan assays are used for the assessment of viable cells under various experimental situations.

  7. Radon assay for SNO+

    Energy Technology Data Exchange (ETDEWEB)

    Rumleskie, Janet [Laurentian University, Greater Sudbury, Ontario (Canada)

    2015-12-31

    The SNO+ experiment will study neutrinos while located 6,800 feet below the surface of the earth at SNOLAB. Though shielded from surface backgrounds, emanation of radon radioisotopes from the surrounding rock leads to back-grounds. The characteristic decay of radon and its daughters allows for an alpha detection technique to count the amount of Rn-222 atoms collected. Traps can collect Rn-222 from various positions and materials, including an assay skid that will collect Rn-222 from the organic liquid scintillator used to detect interactions within SNO+.

  8. FLUIDICS DEVICE FOR ASSAY

    DEFF Research Database (Denmark)

    2007-01-01

    The present invention relates to a device for use in performing assays on standard laboratory solid supports whereon chemical entities are attached. The invention furthermore relates to the use of such a device and a kit comprising such a device. The device according to the present invention is a......, when operatively connected, one or more chambers (21) comprising the chemical entities (41), the inlet(s) (5) and outlet(s) (6) and chambers (21) being in fluid connection. The device further comprise means for providing differing chemical conditions in each chamber (21)....

  9. Growth cone collapse assay.

    Science.gov (United States)

    Cook, Geoffrey M W; Jareonsettasin, Prem; Keynes, Roger J

    2014-01-01

    The growth cone collapse assay has proved invaluable in detecting and purifying axonal repellents. Glycoproteins/proteins present in detergent extracts of biological tissues are incorporated into liposomes, added to growth cones in culture and changes in morphology are then assessed. Alternatively purified or recombinant molecules in aqueous solution may be added directly to the cultures. In both cases after a defined period of time (up to 1 h), the cultures are fixed and then assessed by inverted phase contrast microscopy for the percentage of growth cones showing a collapsed profile with loss of flattened morphology, filopodia, and lamellipodia.

  10. 75 FR 64585 - Bulk Solid Hazardous Materials: Harmonization With the International Maritime Solid Bulk Cargoes...

    Science.gov (United States)

    2010-10-19

    ... nonsubstantive changes, however, to correct grammar, internal paragraph references, and a temperature conversion... means the English version of the ``International Maritime Solid Bulk Cargoes Code'' published by...

  11. RAS - Screens & Assays - Drug Discovery

    Science.gov (United States)

    The RAS Drug Discovery group aims to develop assays that will reveal aspects of RAS biology upon which cancer cells depend. Successful assay formats are made available for high-throughput screening programs to yield potentially effective drug compounds.

  12. Into the Bulk: A Covariant Approach

    CERN Document Server

    Engelhardt, Netta

    2016-01-01

    I propose a general, covariant way of defining when one region is "deeper in the bulk" than another. This definition is formulated outside of an event horizon (or in the absence thereof) in generic geometries; it may be applied to both points and surfaces, and may be used to compare the depth of bulk points or surfaces relative to a particular boundary subregion or relative to the entire boundary. Using the recently proposed "lightcone cut" formalism, the comparative depth between two bulk points can be determined from the singularity structure of Lorentzian correlators in the dual field theory. I prove that, by this definition, causal wedges of progressively larger regions probe monotonically deeper in the bulk. The definition furthermore matches expectations in pure AdS and in static AdS black holes with isotropic spatial slices, where a well-defined holographic coordinate exists. In terms of holographic RG flow, this new definition of bulk depth makes contact with coarse-graining over both large distances ...

  13. Development of superconductor bulk for superconductor bearing

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Joong; Jun, Byung Hyuk; Park, Soon Dong (and others)

    2008-08-15

    Current carrying capacity is one of the most important issues in the consideration of superconductor bulk materials for engineering applications. There are numerous applications of Y-Ba-Cu-O (YBCO) bulk superconductors e.g. magnetic levitation train, flywheel energy storage system, levitation transportation, lunar telescope, centrifugal device, magnetic shielding materials, bulk magnets etc. Accordingly, to obtain YBCO materials in the form of large, single crystals without weak-link problem is necessary. A top seeded melt growth (TSMG) process was used to fabricate single crystal YBCO bulk superconductors. The seeded and infiltration growth (IG) technique was also very promising method for the synthesis of large, single-grain YBCO bulk superconductors with good superconducting properties. 5 wt.% Ag doped Y211 green compacts were sintered at 900 .deg. C {approx} 1200 .deg.C and then a single crystal YBCO was fabricated by an infiltration method. A refinement and uniform distribution of the Y211 particles in the Y123 matrix were achieved by sintering the Ag-doped samples. This enhancement of the critical current density was ascribable to a fine dispersion of the Y211 particles, a low porosity and the presence of Ag particles. In addition, we have designed and manufactured large YBCO single domain with levitation force of 10-13 kg/cm{sup 2} using TSMG processing technique.

  14. LC determination of rosiglitazone in bulk and pharmaceutical formulation.

    Science.gov (United States)

    Radhakrishna, T; Satyanarayana, J; Satyanarayana, A

    2002-07-31

    An isocratic reversed phase liquid chromatographic (RP-LC) method has been developed and subsequently validated for the determination of rosiglitazone and its related impurities. Separation was achieved with a Symmetry C18 column and sodium phosphate buffer (pH adjusted to 6.2):acetonitrile (50:50, v/v) as eluent, at a flow rate of 1.0 ml/min. UV detection was performed at 245 nm. The method is simple, rapid, selective and stability indicating. Indole was used as internal standard for the purpose of quantification of rosiglitazone. The described method is linear over a range of 0.45-10 microg/ml for related impurities and 180-910 microg/ml for assay of rosiglitazone. The method precision for the determination of assay and related compounds was below 1.0 and 3.6% RSD, respectively. The mean recoveries of impurities were found to be in the range of 95-102%. The percentage recoveries of Active Pharmaceutical Ingredient (API) from dosage forms ranged from 99.02 to 101.30. The method is useful in the quality control of bulk manufacturing and also in pharmaceutical formulations.

  15. Between Right and Left Handed Media

    CERN Document Server

    Ingrey, P C; Jakeman, E; French, O E

    2008-01-01

    We report analytical calculations for the propagation of electromagnetic radiation through an inhomogeneous layer whose refractive index varies in one dimension situated between bulk right- and left-handed media. Significant field localization is generated in the layer that is caused by the coherent superposition of evanescent waves. The strength of the field localization and the transmission properties of the layer are investigated as a function of the layer width, losses and defects in the refractive index; the former two being modelled by continuous changes, and the latter by discontinuous changes, in the index profile.

  16. Bulk fields from the boundary OPE

    CERN Document Server

    Guica, Monica

    2016-01-01

    Previous work has established an equality between the geodesic integral of a free bulk field in AdS and the contribution of the conformal descendants of its dual CFT primary operator to the OPE of two other operators inserted at the endpoints of the geodesic. Working in the context of AdS$_3$/CFT$_2$, we extend this relation to include all $1/N$ corrections to the bulk field obtained by dressing it with i) a $U(1)$ current and ii) the CFT stress tensor, and argue it equals the contribution of the Ka\\v{c}-Moody/the Virasoro block to the respective boundary OPE. This equality holds for a particular framing of the bulk field to the boundary that involves a split Wilson line.

  17. A Diphoton Resonance from Bulk RS

    CERN Document Server

    Csaki, Csaba

    2016-01-01

    Recent LHC data hints at a 750 GeV mass resonance that decays into two photons. A significant feature of this resonance is that its decays to Higges and to any other Standard Model particles are so far too low to be detected. Such a state has a compelling explanation in terms of a scalar or a pseudoscalar that is strongly coupled to vector states charged under the Standard Model gauge groups. We argue that if the state is a scalar, some form of sequestering is likely to be necessary to naturally explain the suppressed scalar-Higgs interactions. Such a scenario is readily accommodated in bulk RS with a scalar localized in the bulk away from the Higgs. Turning this around, we argue that a good way to find the elusive bulk RS model might be the search for a resonance with prominent couplings to gauge bosons.

  18. Bulk Comptonization by Turbulence in Accretion Disks

    CERN Document Server

    Kaufman, J

    2016-01-01

    Radiation pressure dominated accretion discs around compact objects may have turbulent velocities that greatly exceed the electron thermal velocities within the disc. Bulk Comptonization by the turbulence may therefore dominate over thermal Comptonization in determining the emergent spectrum. Bulk Comptonization by divergenceless turbulence is due to radiation viscous dissipation only. It can be treated as thermal Comptonization by solving the Kompaneets equation with an equivalent "wave" temperature, which is a weighted sum over the power present at each scale in the turbulent cascade. Bulk Comptonization by turbulence with non-zero divergence is due to both pressure work and radiation viscous dissipation. Pressure work has negligible effect on photon spectra in the limit of optically thin turbulence, and in this limit radiation viscous dissipation alone can be treated as thermal Comptonization with a temperature equivalent to the full turbulent power. In the limit of extremely optically thick turbulence, ra...

  19. A diphoton resonance from bulk RS

    Science.gov (United States)

    Csáki, Csaba; Randall, Lisa

    2016-07-01

    Recent LHC data hinted at a 750 GeV mass resonance that decays into two photons. A significant feature of this resonance is that its decays to any other Standard Model particles would be too low to be detected so far. Such a state has a compelling explanation in terms of a scalar or a pseudoscalar that is strongly coupled to vector states charged under the Standard Model gauge groups. Such a scenario is readily accommodated in bulk RS with a scalar localized in the bulk away from but close to the Higgs. Turning this around, we argue that a good way to find the elusive bulk RS model might be the search for a resonance with prominent couplings to gauge bosons.

  20. Orchestrating Bulk Data Movement in Grid Environments

    Energy Technology Data Exchange (ETDEWEB)

    Vazhkudai, SS

    2005-01-25

    Data Grids provide a convenient environment for researchers to manage and access massively distributed bulk data by addressing several system and transfer challenges inherent to these environments. This work addresses issues involved in the efficient selection and access of replicated data in Grid environments in the context of the Globus Toolkit{trademark}, building middleware that (1) selects datasets in highly replicated environments, enabling efficient scheduling of data transfer requests; (2) predicts transfer times of bulk wide-area data transfers using extensive statistical analysis; and (3) co-allocates bulk data transfer requests, enabling parallel downloads from mirrored sites. These efforts have demonstrated a decentralized data scheduling architecture, a set of forecasting tools that predict bandwidth availability within 15% error and co-allocation architecture, and heuristics that expedites data downloads by up to 2 times.

  1. Multiphase composites with extremal bulk modulus

    DEFF Research Database (Denmark)

    Gibiansky, L. V.; Sigmund, Ole

    2000-01-01

    This paper is devoted to the analytical and numerical study of isotropic elastic composites made of three or more isotropic phases. The ranges of their effective bulk and shear moduli are restricted by the Hashin-Shtrikman-Walpole (HSW) bounds. For two-phase composites, these bounds are attainable......, that is, there exist composites with extreme bulk and shear moduli. For multiphase composites, they may or may not be attainable depending on phase moduli and volume fractions. Sufficient conditions of attainability of the bounds and various previously known and new types of optimal composites...... are described. Most of our new results are related to the two-dimensional problem. A numerical topology optimization procedure that solves the inverse homogenization problem is adopted and used to look for two-dimensional three-phase composites with a maximal effective bulk modulus. For the combination...

  2. A stereoscopic look into the bulk

    Science.gov (United States)

    Czech, Bartlomiej; Lamprou, Lampros; McCandlish, Samuel; Mosk, Benjamin; Sully, James

    2016-07-01

    We present the foundation for a holographic dictionary with depth perception. The dictionary consists of natural CFT operators whose duals are simple, diffeomorphisminvariant bulk operators. The CFT operators of interest are the "OPE blocks," contributions to the OPE from a single conformal family. In holographic theories, we show that the OPE blocks are dual at leading order in 1 /N to integrals of effective bulk fields along geodesics or homogeneous minimal surfaces in anti-de Sitter space. One widely studied example of an OPE block is the modular Hamiltonian, which is dual to the fluctuation in the area of a minimal surface. Thus, our operators pave the way for generalizing the Ryu-Takayanagi relation to other bulk fields.

  3. Spherically symmetric brane spacetime with bulk gravity

    Science.gov (United States)

    Chakraborty, Sumanta; SenGupta, Soumitra

    2015-01-01

    Introducing term in the five-dimensional bulk action we derive effective Einstein's equation on the brane using Gauss-Codazzi equation. This effective equation is then solved for different conditions on dark radiation and dark pressure to obtain various spherically symmetric solutions. Some of these static spherically symmetric solutions correspond to black hole solutions, with parameters induced from the bulk. Specially, the dark pressure and dark radiation terms (electric part of Weyl curvature) affect the brane spherically symmetric solutions significantly. We have solved for one parameter group of conformal motions where the dark radiation and dark pressure terms are exactly obtained exploiting the corresponding Lie symmetry. Various thermodynamic features of these spherically symmetric space-times are studied, showing existence of second order phase transition. This phenomenon has its origin in the higher curvature term with gravity in the bulk.

  4. Managing Ammonia Emissions From Screwworm Larval Rearing Media.

    Science.gov (United States)

    Sagel, Agustin; Phillips, Pamela; Chaudhury, Muhammad; Skoda, Steven

    2016-02-01

    Mass production, sterilization, and release of screwworms (Cochliomyia hominivorax (Coquerel)) that were competitive in the field significantly contributed to the successful application of the sterile insect technique for eradication of screwworms from continental North America. Metabolic byproducts resulting from protein-rich diets required for larval screwworms lead to ammonia liberation, sometimes at high levels, within the mass rearing facility. Until recently a sodium polyacrylate gel bulking agent was used for the larval media and adsorbed much of the ammonia. A need to replace the gel with an environmentally "friendly" bulking agent, while not increasing ammonia levels in the rearing facility, led to a series of experiments with the objective of developing procedures to reduce ammonia emissions from the larval media bulked with cellulose fiber. Additives of ammonia-converting bacteria, potassium permanganate, and Yucca schidigera Roezl ex Otrgies powder extract, previously reported to reduce ammonia levels in organic environments, were evaluated. Ammonia-converting bacteria did not have a positive effect. Addition of Y. schidigera powder extract (∼1% of total volume), potassium permanganate (∼250 ppm), and a combination of these two additives (at these same concentrations) kept ammonia at equivalent levels as when larval media was bulked with gel. Potassium permanganate also had sufficient antimicrobial properties that the use of formaldehyde in the diet was not necessary. Further testing is needed, at a mass rearing level, before full implementation into the screwworm eradication program.

  5. Organizational Communication and Media

    DEFF Research Database (Denmark)

    Tække, Jesper

      The paper reflects an interest in the relation between organizational communication and media. It tries to answer the question, how we can observe the relationship between organizational communication and media. It is a work-in-progress which tries to combine organizational studies inspired...... of Niklas Luhmann (Tække & Paulsen 2008, Tække 2008a) with analysis of how organizations communicate in and about media. Using systems theory and form theory, it puts forward a theoretical framework and a strategy for analysing organisational communication in and about media. The medium aspect is inspired...... is a possible framework to draw the two disciplines together in, because it is a theory about the relation between the social and the media it is based on. First the paper sum up the Luhmann inspired theory about organizations, fleshing out how organizations are thought to communicate in and about media and how...

  6. Pervasive media violence.

    Science.gov (United States)

    Schooler, C; Flora, J A

    1996-01-01

    In this review, we focus our discussion on studies examining effects on children and young adults. We believe that the current epidemic of youth violence in the United States justifies a focus on this vulnerable segment of society. We consider media effects on individual children's behaviors, such as imitating aggressive acts. In addition, we examine how the media influence young people's perceptions of norms regarding interpersonal relationships. Next, we assess mass media effects on societal beliefs, or what children and adolescents think the "real world" is like. We suggest these media influences are cumulative and mutually reinforcing, and discuss the implications of repeated exposure to prominent and prevalent violent media messages. Finally, we catalog multiple intervention possibilities ranging from education to regulation. From a public health perspective, therefore, we evaluate the effects that pervasive media messages depicting violence have on young people and present multiple strategies to promote more healthful outcomes.

  7. The Media Mixer

    DEFF Research Database (Denmark)

    Vestergaard, Vitus; Mortensen, Christian Hviid

    In recent years many museums have experimented with different approaches to involving users through digital media. We explore how remixing and content sharing can be used as a means for user participation. Remix culture is seen as a culture that allows and encourages the production of derivative...... the museum users can produce, deconstruct, reconstruct and finally publish and share digital media content. The media content is created by the user in the museums physical environment, but it can be mixed with material from local or global archives. In that way the gap between the analogue and the digital...... works; works that are based on already existing works. This cultural practice thrives throughout the Internet, most notably on web2.0 sites like YouTube. The Media Museum has embraced the remix paradigm with the development of an interactive media experience centre called the Media Mixer. Here...

  8. Packing Optimization of Sorbent Bed Containing Dissimilar and Irregular Shaped Media

    Science.gov (United States)

    Holland, Nathan; Guttromson, Jayleen; Piowaty, Hailey

    2011-01-01

    The Fire Cartridge is a packed bed air filter with two different and separate layers of media designed to provide respiratory protection from combustion products after a fire event on the International Space Station (ISS). The first layer of media is a carbon monoxide catalyst and the second layer of media is universal carbon. During development of Fire Cartridge prototypes, the two media beds were noticed to have shifted inside the cartridge. The movement of media within the cartridge can cause mixing of the bed layers, air voids, and channeling, which could cause preferential air flow and allow contaminants to pass through without removal. An optimally packed bed mitigates these risks and ensures effective removal of contaminants from the air. In order to optimally pack each layer, vertical, horizontal, and orbital agitations were investigated and a packed bulk density was calculated for each method. Packed bulk density must be calculated for each media type to accommodate variations in particle size, shape, and density. Additionally, the optimal vibration parameters must be re-evaluated for each batch of media due to variations in particle size distribution between batches. For this application it was determined that orbital vibrations achieve an optimal pack density and the two media layers can be packed by the same method. Another finding was media with a larger size distribution of particles achieve an optimal bed pack easier than media with a smaller size distribution of particles.

  9. Making bulk-conductive glass microchannel plates

    Science.gov (United States)

    Yi, Jay J. L.; Niu, Lihong

    2008-02-01

    The fabrication of microchannel plate (MCP) with bulk-conductive characteristics has been studied. Semiconducting clad glass and leachable core glass were used for drawing fibers and making MCP. Co-axial single fiber was drawn from a platinum double-crucible in an automatic fiberizing system, and the fibers were stacked and redrawn into multifiber by a special gripping mechanism. The multifibers were stacked again and the boule was made and sliced into discs. New MCPs were made after chemically leaching process without the traditional hydrogen firing. It was shown that bulk-conductive glass MCP can operate at higher voltage with lower noise.

  10. Synthesis of Bulk Superconducting Magnesium Diboride

    Directory of Open Access Journals (Sweden)

    Margie Olbinado

    2002-06-01

    Full Text Available Bulk polycrystalline superconducting magnesium diboride, MgB2, samples were successfully prepared via a one-step sintering program at 750°C, in pre Argon with a pressure of 1atm. Both electrical resistivity and magnetic susceptibility measurements confirmed the superconductivity of the material at 39K, with a transition width of 5K. The polycrystalline nature, granular morphology, and composition of the sintered bulk material were confirmed using X-ray diffractometry (XRD, scanning electron microscopy (SEM, and energy dispersive X-ray analysis (EDX.

  11. Towards a Reconstruction of General Bulk Metrics

    CERN Document Server

    Engelhardt, Netta

    2016-01-01

    We prove that the metric of a general holographic spacetime can be reconstructed (up to an overall conformal factor) from distinguished spatial slices - "light-cone cuts" - of the conformal boundary. Our prescription is covariant and applies to bulk points in causal contact with the boundary. Furthermore, we describe a procedure for determining the light-cone cuts corresponding to bulk points in the causal wedge of the boundary in terms of the divergences of correlators in the dual field theory. Possible extensions for determining the conformal factor and including the cuts of points outside of the causal wedge are discussed. We also comment on implications for subregion/subregion duality.

  12. Vibrationally-Fluidized Granular Flows: Impact and Bulk Velocity Measurements Compared with Discrete Element and Continuum Models

    Science.gov (United States)

    Hashemnia, Kamyar

    A new laser displacement probe was developed to measure the impact velocities of particles within vibrationally-fluidized beds. The sensor output was also used to measure bulk flow velocity along the probe window and to provide a measure of the media packing. The displacement signals from the laser sensors were analyzed to obtain the probability distribution functions of the impact velocity of the particles. The impact velocity was affected by the orientation of the laser probe relative to the bulk flow velocity, and the density and elastic properties of the granular media. The impact velocities of the particles were largely independent of their bulk flow speed and packing density. Both the local impact and bulk flow velocities within a tub vibratory finisher were predicted using discrete element modelling (DEM) and compared to the measured values for spherical steel media. It was observed that the impact and bulk flow velocities were relatively insensitive to uncertainties in the contact coefficients of friction and restitution. It was concluded that the predicted impact and bulk flow velocities were dependent on the number of layers in the model. Consequently, the final DE model mimicked the key aspects of the experimental setup, including the submerged laser sensor. The DE method predictions of both impact velocity and bulk flow velocity were in reasonable agreement with the experimental measurements, with maximum differences of 20% and 30%, respectively. Discrete element modeling of granular flows is effective, but requires large numerical models. In an effort to reduce computational effort, this work presents a finite element (FE) continuum model of a vibrationally-fluidized granular flow. The constitutive equations governing the continuum model were calibrated using the discrete element method (DEM). The bulk flow behavior of the equivalent continuum media was then studied using both Lagrangian and Eulerian FE formulations. The bulk flow velocities predicted

  13. Bacterial assays for recombinagens.

    Science.gov (United States)

    Hoffmann, G R

    1992-12-01

    Two principal strategies have been used for studying recombinagenic effects of chemicals and radiation in bacteria: (1) measurement of homologous recombination involving defined alleles in a partially diploid strain, and (2) measurement of the formation and loss of genetic duplications in the bacterial chromosome. In the former category, most methods involve one allele in the bacterial chromosome and another in a plasmid, but it is also possible to detect recombination between two chromosomal alleles or between two extrachromosomal alleles. This review summarizes methods that use each of these approaches for detecting recombination and tabulates data on agents that have been found to be recombinagenic in bacteria. The assays are discussed with respect to their effectiveness in testing for recombinagens and their potential for elucidating mechanisms underlying recombinagenic effects.

  14. Strategy and New Media

    DEFF Research Database (Denmark)

    Plesner, Ursula; Gulbrandsen, Ib Tunby

    2015-01-01

    Despite current attention to the materiality of organizations and the performative role of tools, devices, artefacts and objects in processes of strategy-making, the impact of new media has not been thoroughly conceptualized in the strategy literature. We argue that new media challenge core...... of new media, this research agenda should be informed by a socio-material sensibility, network thinking and a longitudinal perspective. Keywords...

  15. Social Media: Human Life

    Directory of Open Access Journals (Sweden)

    Nick Couldry

    2015-04-01

    Full Text Available This article explores the idea that research into media communications and information has recently undergone a normative turn as more and more writers reflect on the ever deeper embedding of our lives in media, and the possible costs that this entails. Possible ways forward for deepening and addressing this normative turn are explored, based on the particular contribution to media and communications research of social theory.

  16. What is Media Innovation?

    OpenAIRE

    2014-01-01

    In order to understand and explain current developments in the media landscape, using the lens of innovation and innovation theory adds value to media research. This chapter gives a theoretical introduction to the concept of innovation. It argues that media innovations may be related to product innovation, process innovation, position innovation, paradigmatic innovation and social innovation, and that innovation may involve different degrees of novelty. The chapter also highlights key influen...

  17. Division Level Social Media

    Science.gov (United States)

    2015-06-12

    networking , the pre-cursor to social media, began in the 1990s.2 Later the term social media became predominant and is the term uses throughout this paper...taken into account with regard to positive or negative effects on the organization? Most social media unit sites are open to the public, which...users. Facebook: a social networking website where users can create a personal profile, add other users as friends, and exchange messages and

  18. Marketing w social media

    OpenAIRE

    Dorenda-Zaborowicz, Marta

    2012-01-01

    The precise definition of social media marketing is hard to establish, but it can be said that it is the methodical use of new technologies and social networks to achieve specific goals for a company. In simple terms social marketing means advertising a company through many different media, like viral videos and blogs, to achieve its maximum exposure. Nevertheless, social media marketing may also refer to advertising certain social issues, such as NGOs’ or civic actions’ promotion. Precyzy...

  19. Bulk milk ELISA and the diagnosis of parasite infections in dairy herds: a review.

    Science.gov (United States)

    Sekiya, Mary; Zintl, Annetta; Doherty, Michael L

    2013-07-25

    The bulk milk enzyme-linked immune sorbent assay (ELISA) is a rapid and inexpensive method of assessing herd exposure to pathogens that is increasingly being used for the diagnosis of parasite infections in dairy herds. In this paper, with the dairy herd health veterinarian in mind, we review the principles of the assay and the recent literature on the potential role of bulk milk ELISA for the diagnosis of ostertagiosis, fasciolosis, parasitic bronchitis due to cattle lung worm and neosporosis. It is generally accepted that assay results reflect exposure to the parasite rather than the presence of active infection. Bulk milk ELISA can be a useful tool for the veterinary practitioner as a component of a herd health monitoring programme or in the context of a herd health investigation. It can also play a role in regional or national surveillance programmes. However, the results need to be interpreted within the context of the herd-specific health management, the milk production pattern and the parasite life cycle.

  20. Overview: new media.

    Science.gov (United States)

    O'Keeffe, Gwenn Schurgin

    2012-06-01

    Pediatricians care for children's growth and development from the time they are born until they become adults. In addition, pediatricians must be vigilant for external influences. Technology influences children of all ages. Seventy-five percent of teenagers own cell phones, with 25% using them for social media. Technology can lead to an increase in skills and social benefits but there is also the potential for harm such as sexting, cyberbullying, privacy issues, and Internet addiction, all of which can affect health. Pediatricians must become well versed in the new media to provide media-oriented anticipatory guidance and advice on media-related issues.

  1. Media multitasking in adolescence.

    Science.gov (United States)

    Cain, Matthew S; Leonard, Julia A; Gabrieli, John D E; Finn, Amy S

    2016-12-01

    Media use has been on the rise in adolescents overall, and in particular, the amount of media multitasking-multiple media consumed simultaneously, such as having a text message conversation while watching TV-has been increasing. In adults, heavy media multitasking has been linked with poorer performance on a number of laboratory measures of cognition, but no relationship has yet been established between media-multitasking behavior and real-world outcomes. Examining individual differences across a group of adolescents, we found that more frequent media multitasking in daily life was associated with poorer performance on statewide standardized achievement tests of math and English in the classroom, poorer performance on behavioral measures of executive function (working memory capacity) in the laboratory, and traits of greater impulsivity and lesser growth mindset. Greater media multitasking had a relatively circumscribed set of associations, and was not related to behavioral measures of cognitive processing speed, implicit learning, or manual dexterity, or to traits of grit and conscientiousness. Thus, individual differences in adolescent media multitasking were related to specific differences in executive function and in performance on real-world academic achievement measures: More media multitasking was associated with poorer executive function ability, worse academic achievement, and a reduced growth mindset.

  2. The digital media handbook

    CERN Document Server

    Dewdney, Andrew

    2013-01-01

    The new edition of The Digital Media Handbook presents an essential guide to the historical and theoretical development of digital media, emphasising cultural continuity alongside technological change, and highlighting the emergence of new forms of communication in contemporary networked culture.Andrew Dewdney and Peter Ride present detailed critical commentary and descriptive historical accounts, as well as a series of interviews from a range of digital media practitioners, including producers, developers, curators and artists.The Digital Media Handbook highlights key concerns of today's prac

  3. Antennas in inhomogeneous media

    CERN Document Server

    Galejs, Janis; Fock, V A; Wait, J R

    2013-01-01

    Antennas in Inhomogeneous Media details the methods of analyzing antennas in such inhomogeneous media. The title covers the complex geometrical configurations along with its variational formulations. The coverage of the text includes various conditions the antennas are subjected to, such as antennas in the interface between two media; antennas in compressible isotropic plasma; and linear antennas in a magnetoionic medium. The selection also covers insulated loops in lossy media; slot antennas with a stratified dielectric or isotropic plasma layers; and cavity-backed slot antennas. The book wil

  4. Sosiaalinen media ja markkinointi

    OpenAIRE

    Salmela, Mikko

    2014-01-01

    Opinnäytetyön toimeksiantajana oli mainostoimisto Media M1. Media M1 on Jyväskyläläinen mainostoimisto, jossa suunnitellaan ja toteutetaan markkinointia printti- ja digimedioihin. Opinnäytetyön aiheeksi valittiin sosiaalinen media ja sen hyödyntäminen markkinoinnissa. Nykyaikana yhä useampi yritys on alkanut siirtyä markkinoimaan myös sosiaalisessa mediassa. Tämän takia Media M1 halusi saada ajankohtaisen selvityksen palveluiden tilanteesta. Opinnäytetyössä selvitettiin sosiaalisen median...

  5. 应用6种M-H培养基测试磺胺类药物抑菌圈直径的结果分析%Analysis of assay results of antimicrobial zone diameters by sulfomides using six Mueller-Hinton media

    Institute of Scientific and Technical Information of China (English)

    闫东辉; 张淑兰; 许淑珍; 李志安

    2001-01-01

    目的对6种M-H培养基进行比较,选择测试磺胺类药物的最佳Mueller-Hinton(M-H)培养基。方法按照NCCLS的要求,采用纸片扩散法,在6种M-H培养基上用3株标准菌株:粪肠球菌(ATCC 29212),大肠埃希菌(ATCC 25922),金黄色葡萄球菌(ATCC 25923)对(SMZco)分别进行50次测定。用10株测试菌株在6种M-H培养基上对SMZco分别进行10次测定。结果美国Difco公司和英国Oxoid公司的M-H培养基在用粪肠球菌ATCC 29212测试SMZco抑菌圈直径时,50次抑菌圈直径测定值均大于20 mm,其他四种M-H培养基的测定值都小于20 mm。用大肠埃希菌(ATCC 25922),金黄色葡萄球菌(ATCC 25923)测试SMZco抑菌圈直径时,6种M-H培养基的全部测定值都在NCCLS规定的范围内。10株测试菌株对SMZco的抑菌圈直径测定,除Difco公司和Oxoid公司M-H培养基外,其他4种M-H培养基均存在不同程度的双环现象。结论 Difco公司和Oxoid公司M-H培养基合格,其他4种均不符合要求。%Objective Six M-H media were compared for selecting the best M-H in the sulfomides antimicrobialtest. Methods According to NCCLS, paper disks diffusion method were adopetd, 3 standard strains for E. faecalis(ATCC 229212), E.coli(ATCC 25922) and S. aureus(ATCC 25923) each were used to test SMZco 50 times on six M-H media;10 test strains each were used to test SMZco 10 times on six M-H media. Results 50 times inhibitory zone diameters>20 mm when E. faecalis(ATCC 29212) were tested to SMZco by using Difco and Oxoid company M-H media, 50 times inhibitory zone diameters<20 mm when other four M-H media were used. All test results in NCCLS limits when using E.coli (ATCC 25922) and S.aureus(ATCC 25923) to test SMZco on six M-H media. When 10 test strains were used to test SMZco zone diameters, other four M-H media possess different degree double ring phenomena except for Difco and Oxoid company M-H media. Conclusion Difco and Oxoid company M-H media are

  6. THE OPTIMIZATION OF PLUSH YARNS BULKING PROCESS

    Directory of Open Access Journals (Sweden)

    VINEREANU Adam

    2014-05-01

    Full Text Available This paper presents the experiments that were conducted on the installation of continuous bulking and thermofixing “SUPERBA” type TVP-2S for optimization of the plush yarns bulking process. There were considered plush yarns Nm 6.5/2, made of the fibrous blend of 50% indigenous wool sort 41 and 50% PES. In the first stage, it performs a thermal treatment with a turboprevaporizer at a temperature lower than thermofixing temperature, at atmospheric pressure, such that the plush yarns - deposed in a freely state on a belt conveyor - are uniformly bulking and contracting. It was followed the mathematical modeling procedure, working with a factorial program, rotatable central composite type, and two independent variables. After analyzing the parameters that have a direct influence on the bulking degree, there were selected the pre-vaporization temperature (coded x1,oC and the velocity of belt inside pre-vaporizer (coded x 2, m/min. As for the dependent variable, it was chosen the plush yarn diameter (coded y, mm. There were found the coordinates of the optimal point, and then this pair of values was verified in practice. These coordinates are: x1optim= 90oC and x 2optim= 6.5 m/min. The conclusion is that the goal was accomplished: it was obtained a good cover degree f or double-plush carpets by reducing the number of tufts per unit surface.

  7. The Bulk Multicore Architecture for Improved Programmability

    Science.gov (United States)

    2009-12-01

    dependences bundled together. In the Bulk Multi- core, the log must store only the total order of chunk commits, an approach we call DeLorean .13 The...ACM Press, New York, 2007, 69–80. 13. Montesinos, P., Ceze, L., and Torrellas, J. DeLorean : Recording and deterministically replaying shared

  8. Failure by fracture in bulk metal forming

    DEFF Research Database (Denmark)

    Silva, C.M.A.; Alves, Luis M.; Nielsen, Chris Valentin

    2015-01-01

    This paper revisits formability in bulk metal forming in the light of fundamental concepts of plasticity,ductile damage and crack opening modes. It proposes a new test to appraise the accuracy, reliability and validity of fracture loci associated with crack opening by tension and out-of-plane she...

  9. Bulk viscosity effects on ultrasonic thermoacoustic instability

    Science.gov (United States)

    Lin, Jeffrey; Scalo, Carlo; Hesselink, Lambertus

    2016-11-01

    We have carried out unstructured fully-compressible Navier-Stokes simulations of a minimal-unit traveling-wave ultrasonic thermoacoustic device in looped configuration. The model comprises a thermoacoustic stack with 85% porosity and a tapered area change to suppress the fundamental standing-wave mode. A bulk viscosity model, which accounts for vibrational and rotational molecular relaxation effects, is derived and implemented via direct modification of the viscous stress tensor, τij ≡ 2 μSij +λ/2 μ ∂uk/∂xk δij , where the bulk viscosity is defined by μb ≡ λ +2/3 μ . The effective bulk viscosity coefficient accurately captures acoustic absorption from low to high ultrasonic frequencies and matches experimental wave attenuation rates across five decades. Using pressure-based similitude, the model was downscaled from total length L = 2 . 58 m to 0 . 0258 m, corresponding to the frequency range f = 242 - 24200 Hz, revealing the effects of bulk viscosity and direct modification of the thermodynamic pressure. Simulations are carried out to limit cycle and exhibit growth rates consistent with linear stability analyses, based on Rott's theory.

  10. Forming of bulk metallic glass microcomponents

    DEFF Research Database (Denmark)

    Wert, John A.; Thomsen, Christian; Jensen, Rune Debel

    2009-01-01

    The present article considers forward extrusion, closed-die forging and backward extrusion processes for fabrication of individual microcomponents from two bulk metallic glass (BMG) compositions: Mg60Cu30Y10 and Zr44Cu40Ag8Al8. Two types of tooling were used in the present work: relatively massive...

  11. Polymer-fullerene bulk heterojunction solar cells

    NARCIS (Netherlands)

    Janssen, RAJ; Hummelen, JC; Saricifti, NS

    2005-01-01

    Nanostructured phase-separated blends, or bulk heterojunctions, of conjugated Polymers and fullerene derivatives form a very attractive approach to large-area, solid-state organic solar cells.The key feature of these cells is that they combine easy, processing from solution on a variety of substrate

  12. Fluctuating brane in a dilatonic bulk

    CERN Document Server

    Brax, P; Rodríguez-Martinez, M; Brax, Philippe; Langlois, David; Rodriguez-Martinez, Maria

    2003-01-01

    We consider a cosmological brane moving in a static five-dimensional bulk spacetime endowed with a scalar field whose potential is exponential. After studying various cosmological behaviours for the homogeneous background, we investigate the fluctuations of the brane that leave spacetime unaffected. A single mode embodies these fluctuations and obeys a wave equation which we study for bouncing and ever-expanding branes.

  13. Longitudinal bulk a coustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja;

    2009-01-01

    Design, fabrication and characterization, in terms of mass sensitivity, is presented for a polycrystalline silicon longitudinal bulk acoustic cantilever. The device is operated in air at 51 MHz, resulting in a mass sensitivity of 100 HZ/fg (1 fg = 10{su−15 g). The initial characterization...

  14. A Stereoscopic Look into the Bulk

    CERN Document Server

    Czech, Bartlomiej; McCandlish, Samuel; Mosk, Benjamin; Sully, James

    2016-01-01

    We present the foundation for a holographic dictionary with depth perception. The dictionary consists of natural CFT operators whose duals are simple, diffeomorphism-invariant bulk operators. The CFT operators of interest are the "OPE blocks," contributions to the OPE from a single conformal family. In holographic theories, we show that the OPE blocks are dual at leading order in 1/N to integrals of effective bulk fields along geodesics or homogeneous minimal surfaces in anti-de Sitter space. One widely studied example of an OPE block is the modular Hamiltonian, which is dual to the fluctuation in the area of a minimal surface. Thus, our operators pave the way for generalizing the Ryu-Takayanagi relation to other bulk fields. Although the OPE blocks are non-local operators in the CFT, they admit a simple geometric description as fields in kinematic space--the space of pairs of CFT points. We develop the tools for constructing local bulk operators in terms of these non-local objects. The OPE blocks also allow ...

  15. Some Media Relations Success Stories.

    Science.gov (United States)

    Sperbeck, John M.

    1997-01-01

    A panel of 29 extension faculty/staff members who work well with the media were interviewed to identify ways to improve their media relations. Reasons for working with the media, ways to develop relationships with media representatives, and suggestions for creating a more favorable climate for media relations in universities were noted. (JOW)

  16. Integration of bulk piezoelectric materials into microsystems

    Science.gov (United States)

    Aktakka, Ethem Erkan

    Bulk piezoelectric ceramics, compared to deposited piezoelectric thin-films, provide greater electromechanical coupling and charge capacity, which are highly desirable in many MEMS applications. In this thesis, a technology platform is developed for wafer-level integration of bulk piezoelectric substrates on silicon, with a final film thickness of 5-100microm. The characterized processes include reliable low-temperature (200°C) AuIn diffusion bonding and parylene bonding of bulk-PZT on silicon, wafer-level lapping of bulk-PZT with high-uniformity (+/-0.5microm), and low-damage micro-machining of PZT films via dicing-saw patterning, laser ablation, and wet-etching. Preservation of ferroelectric and piezoelectric properties is confirmed with hysteresis and piezo-response measurements. The introduced technology offers higher material quality and unique advantages in fabrication flexibility over existing piezoelectric film deposition methods. In order to confirm the preserved bulk properties in the final film, diaphragm and cantilever beam actuators operating in the transverse-mode are designed, fabricated and tested. The diaphragm structure and electrode shapes/sizes are optimized for maximum deflection through finite-element simulations. During tests of fabricated devices, greater than 12microm PP displacement is obtained by actuation of a 1mm2 diaphragm at 111kHz with management IC, which incorporates a supply-independent bias circuitry, an active diode for low-dropout rectification, a bias-flip system for higher efficiency, and a trickle battery charger. The overall system does not require a pre-charged battery, and has power consumption of sleep-mode (simulated). Under lg vibration at 155Hz, a 70mF ultra-capacitor is charged from OV to 1.85V in 50 minutes.

  17. 46 CFR 148.04-23 - Unslaked lime in bulk.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Unslaked lime in bulk. 148.04-23 Section 148.04-23... HAZARDOUS MATERIALS IN BULK Special Additional Requirements for Certain Material § 148.04-23 Unslaked lime in bulk. (a) Unslaked lime in bulk must be transported in unmanned, all steel, double-hulled...

  18. Reconceptualizing (new media literacy

    Directory of Open Access Journals (Sweden)

    Petra Aczel

    2014-02-01

    Full Text Available This paper aims to introduce a theoretical-critical approach which shall revisit elements and cast light upon subsets of (new media literacy. It endeavours to draw community, spatial, procedural and aural literacy (auralacy into consideration, relating them to the complex of media literacy, striving to provide invigorating insights into its conceptual foundations and integrated perspectives for its pedagogy.

  19. Eosinofiele otitis media

    NARCIS (Netherlands)

    de Jong, Monique A M; Smithuis, L O M J Otto; Stokroos, Robert J

    2014-01-01

    BACKGROUND: Eosinophilic otitis media (EOM) is a rare middle ear disease that may closely resemble therapy-resistant otitis media with effusion (OME). The diagnosis is made if eosinophil-rich fluid is present with two or more of the following minor criteria: (a) history of nasal polyps or, (b) bronc

  20. Corporate Media Governance

    NARCIS (Netherlands)

    Kempen, Petrus Cornelis

    2011-01-01

    The media can make or break a reputation. This being said, it seems to be essential for companies, governments and institutions to pay specific attention to corporate media management in their daily operations. However, this thesis shows that they often neglect to pay adequate attention to corporate

  1. Social Media. Research Brief

    Science.gov (United States)

    Williamson, Ronald

    2010-01-01

    The growing use of social media by students and adults is impacting schools. A recent Pew study found that 73% of teens use social-networking sites to connect with others. Social media includes blogs, wikis, and podcasts as well as sites such as MySpace, Facebook, and Linkedin. While such sites promote connection with others, their use has created…

  2. Understanding social media logic

    NARCIS (Netherlands)

    van Dijck, J.; Poell, T.

    2013-01-01

    Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions a

  3. Building Social Media Connections

    Science.gov (United States)

    Ferriter, William N.; Ramsden, Jason T.; Sheninger, Eric C.

    2012-01-01

    Incorporating social media tools into your professional practices does not have to be intimidating as long as you are willing to tackle five action steps. It is far easier to articulate the strengths--and to imagine the possibilities--of social media spaces as tools for communication and professional development when you are actively using those…

  4. Media Specialists Evaluation System.

    Science.gov (United States)

    Reese, Carol; Marsen, Louise

    Intended to provide a comprehensive system for the evaluation of a media specialist's total job performance, this three-part evaluation form is based on the St. Louis Community College's Faculty Evaluation System: Instructional Resources Faculty, August 1981. Designed for peer evaluation of media specialists, the first form includes a rating scale…

  5. Teaching Media Literacy

    Science.gov (United States)

    David, Jane L.

    2009-01-01

    Media literacy is making a comeback, spurred by students' access to unlimited information on the Internet. Can schools provide the skills students need to become media literate in a digital world? Researchers find that reading for understanding online requires the same skills as offline reading, including using prior knowledge and making…

  6. Japanese Media in English.

    Science.gov (United States)

    Tanaka, Sachiko Oda

    1995-01-01

    Describes the use of English in the media in Japan, focusing on the role and history of English-language newspapers, radio, and television programs, as well as the proliferation of English-language films shown in Japanese cinemas. Discusses the implications of English in the Japanese media. (20 references) (MDM)

  7. Digital Media and Learning

    Science.gov (United States)

    John D. and Catherine T. MacArthur Foundation, 2012

    2012-01-01

    MacArthur launched the digital media and learning initiative in 2006 to explore how digital media are changing the way young people learn, socialize, communicate, and play. Since 2006, the Foundation has awarded grants totaling more than $100 million for research, development of innovative new technologies, new learning environments for youth,…

  8. Herbicide resistance screening assay.

    Science.gov (United States)

    Peterson, Joan M

    2009-01-01

    Herbicide resistance screening is a method that can be used not only to determine presence of the enzyme, phosphinothricin acetyltransferase, encoded by either the Bar or the Pat gene in transgenic maize, but also to assess the inheritance ratio of those genes in a segregating population. Herbicide screening can also be used to study linkage of a transgene of interest that was cotransformed with the herbicide resistance marker gene. By combining the herbicide screen assay with a PCR-based screen of leaf tissue DNA for the presence of both the Bar or the Pat gene marker and a cotransformed transgene of interest from the same seedling tissue and maintaining that seedling identity, the researcher can identify linkage or the possible breakdown in linkage of the marker gene and the transgene of interest. Further, the occurrence of "DNA silencing" can be evaluated if an individual seedling that was susceptible to the applied herbicide nonetheless gave PCR data that indicated presence of the gene responsible for herbicide resistance. Similarly, "DNA silencing" of the gene of interest may be investigated if the seeds can be screened and scored for that phenotypic trait in a nondestructive manner prior to planting.

  9. Evaluation of new transport medium for detection of herpes simplex virus by culture and direct enzyme-linked immunosorbent assay.

    Science.gov (United States)

    Ogburn, J R; Hoffpauir, J T; Cole, E; Hood, K; Michael, D; Nguyen, T; Raden, S; Raju, B; Reisinger, V; Oefinger, P E

    1994-12-01

    The transport medium Multi-Microbe Media (M4) was evaluated prospectively by culture and direct enzyme-linked immunosorbent assay (ELISA) for detection of herpes simplex virus from 473 specimens. In addition, 377 specimens in Bartels Viral Transport Medium were evaluated. By using culture as a "gold standard," the ELISA sensitivity was approximately 85%, while the specificities exceeded 96% for both media.

  10. Media Appropriation and Explicitation

    Directory of Open Access Journals (Sweden)

    Tomas Laurenzo

    2016-12-01

    Full Text Available This paper presents a novel characterization of new media art together with an exploration of some key aspects of its practice: I propose that new media art’s defining characteristics are media appropriation and explicitation. With media appropriation I refer to the dialectal inscription into the art practice of the knowledge that allows for some particular technological production. I also propose that new media art’s language is constructed in part via the explicitation of certain aspects of more ‘traditional’ art, and that this explicitation allows for a construction of a new vocabulary. Examples of this are the explicitation of randomness, interaction, programming, or of the role that tools and instruments play, among others.

  11. Social Media Reputation

    DEFF Research Database (Denmark)

    Etter, Michael; Colleoni, Elanor; Ravasi, Davide

    directly to corporate performance and actions. Secondly, prominent reputation measurements couple stakeholders´ believes to reputation drivers through the use of predefined scales and items. We argue that with the rise of social media a company´s reputation has increasingly become autonomous from corporate...... actions, which demands a greater decoupling of stakeholders´ perceptions from corporate signals or actions in corporate reputation research. We develop the concept of social media reputation as the overall evaluation of a company presented in social media and present a new approach of measuring reputation...... based on social media data that accounts for the autonomy of stakeholder´s perception of a firm. We compare and contrast this novel social media reputation measure (SMRM) with traditional reputation measurements and find that SMRM is a valuable measurement to capture the autonomy of the stakeholders...

  12. Social Media Policies

    DEFF Research Database (Denmark)

    Stohl, Cynthia; Etter, Michael; Banghart, Scott

    2015-01-01

    Three global developments situate the context of this investigation: the increasing use of social media by organizations and their employees, the burgeoning presence of social media policies, and the heightened focus on corporate social responsibility (CSR). In this study the intersection...... of these trends is examined through a content analysis of 112 publicly available social media policies from the largest corporations in the world. The extent to which social media policies facilitate and/or constrain the communicative sensibilities and values associated with contemporary notions of CSR...... negotiation and participation in the social responsibilities of corporations. Moreover, policies generally enact organizational communication practices that are contrary to international CSR guidelines (e.g., the UN Global Compact and other international agreements). Findings suggest that social media...

  13. Media Sociography on Weblogs

    DEFF Research Database (Denmark)

    Tække, Jesper

    to the media it is based on. Theoretically seen it is inspired of two theoretical paradigms the Sociological Systems Theory of Niklas Luhmann and the Media Theory (also called the Toronto school). Empirically the paper primary draws on the literature about weblogs, which could be framed as CMC......Weblogs are not only one of the newest technical media for communication, but also one of the most difficult to understand. Are weblogs a kind of mass medium, a personal medium like an online diary, or a medium that gives space for communities to grow? Or are weblogs a medium that enable all...... these possibilities depended on the actual use? This paper throws some light on what weblogs are by using the methodology of Media Sociography (Tække 2003, 2004a, 2004b and 2004c). Media Sociography is a strategy for analysing mediated social systems or in other words a strategy for describing the social in relation...

  14. Subsidizing Media Innovation

    DEFF Research Database (Denmark)

    Kammer, Aske; Hobel, Emil

    2016-01-01

    and economically sustainable activity, the institutionalization of financial support for media innovation constitute one way for policy makers to bring (parts of) the journalistic environment up-to-date with the digital age, thereby improving the conditions for an informed citizenry in the future (Kammer...... analytical approaches (inspired by the methodology of "qualitative media analysis", cf. Altheide & Schneider, 2013), the paper analyzes to what extent the administration reflects a support of the welfare framework the subsidy scheme exists within. It asks (1) which types of news-media innovation gets......When the Danish Parliament revised the media-subsidy framework in 2013/2014, one of the new initiatives was the introduction of a pool of funding earmarked to establishing and developing new news media – the so-called “innovation fund”. So, as the news industry struggles to keep journalism a viable...

  15. Creative Digital Media Practices

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    The presentation reviews the interplay of dialogic (Bakhtin, 1981) and multimodal theories on media production practices, with attention to visual communication (Kress and van Leeuwen, 2001, 2006). This theoretical approach aids in reflecting on digital media practices as novel (new) sign systems...... on collaboration (Benkler, 2006). The shift toward visual modes and digital media practices pose many pedagogical challenges for academics. I want to raise questions on how to teach “dialogically” with and through creative, digital media practices based on my plans for a course in Fall, 2011, where students...... develop a collaborative digital storytelling showcase for their own digital stories about Roskilde University. This course is intended to bring up reflections on the wider phenomenon of contemporary media practices, such as: YouTube, DIY (do-it-yourself) filmmaking or homemade, garage cinema (Jenkins...

  16. Social Justice and Media. Media Corner.

    Science.gov (United States)

    Braun, Joseph A., III, Ed.

    1994-01-01

    Contends that the end of slavery, women's suffrage, and the civil rights movement were watershed events of social justice in U.S. history. Provides reviews of two media-based sets of instructional materials that can help students understand the struggle by disenfranchised groups to become full participants in society. (CFR)

  17. Social media modeling and computing

    CERN Document Server

    Hoi, Steven CH; Boll, Susanne; Xu, Dong; Jin, Rong; King, Irwin

    2011-01-01

    Presents contributions from an international selection of preeminent experts in the field Discusses topics on social-media content analysis, and examines social-media system design and analysis Describes emerging applications of social media

  18. Prevalence of human papillomavirus in 5,072 consecutive cervical SurePath samples evaluated with the Roche cobas HPV real-time PCR assay

    DEFF Research Database (Denmark)

    Preisler, Sarah; Rebolj, Matejka; Untermann, Anette;

    2013-01-01

    New commercially available Human Papillomavirus (HPV) assays need to be evaluated in a variety of cervical screening settings. Cobas HPV Test (cobas) is a real-time PCR-based assay allowing for separate detection of HPV genotypes 16 and 18 and a bulk of 12 other high-risk genotypes. The aim...... of the present study, Horizon, was to assess the prevalence of high-risk HPV infections in an area with a high background risk of cervical cancer, where women aged 23-65 years are targeted for cervical screening. We collected 6,258 consecutive cervical samples from the largest cervical screening laboratory...... in Denmark serving the whole of Copenhagen. All samples were stored in SurePath media. In total, 5,072 samples were tested with cobas, Hybrid Capture 2 High Risk HPV DNA test (HC2) and liquid-based cytology. Of these, 27% tested positive on cobas. This proportion decreased by age, being 43% in women aged 23...

  19. MediaTracker system

    Energy Technology Data Exchange (ETDEWEB)

    Sandoval, D. M. (Dana M.); Strittmatter, R. B. (Richard B.); Abeyta, J. D. (Joline D.); Brown, J. (John); Marks, T. (Thomas), Jr.; Martinez, B. J. (Benny J.); Jones, D. B. (Dana Benelli); Hsue, W.

    2004-01-01

    The initial objectives of this effort were to provide a hardware and software platform that can address the requirements for the accountability of classified removable electronic media and vault access logging. The Media Tracker system software assists classified media custodian in managing vault access logging and Media Tracking to prevent the inadvertent violation of rules or policies for the access to a restricted area and the movement and use of tracked items. The MediaTracker system includes the software tools to track and account for high consequence security assets and high value items. The overall benefits include: (1) real-time access to the disposition of all Classified Removable Electronic Media (CREM), (2) streamlined security procedures and requirements, (3) removal of ambiguity and managerial inconsistencies, (4) prevention of incidents that can and should be prevented, (5) alignment with the DOE's initiative to achieve improvements in security and facility operations through technology deployment, and (6) enhanced individual responsibility by providing a consistent method of dealing with daily responsibilities. In response to initiatives to enhance the control of classified removable electronic media (CREM), the Media Tracker software suite was developed, piloted and implemented at the Los Alamos National Laboratory beginning in July 2000. The Media Tracker software suite assists in the accountability and tracking of CREM and other high-value assets. One component of the MediaTracker software suite provides a Laboratory-approved media tracking system. Using commercial touch screen and bar code technology, the MediaTracker (MT) component of the MediaTracker software suite provides an efficient and effective means to meet current Laboratory requirements and provides new-engineered controls to help assure compliance with those requirements. It also establishes a computer infrastructure at vault entrances for vault access logging, and can

  20. Detection of human metapneumovirus from children with acute otitis media.

    Science.gov (United States)

    Suzuki, Akira; Watanabe, Oshi; Okamoto, Michiko; Endo, Hiroko; Yano, Hisakazu; Suetake, Mitsuko; Nishimura, Hidekazu

    2005-07-01

    Nasal and middle ear specimens collected from children with acute otitis media were subjected to viral isolation and bacteria culture. All virus-negative specimens underwent reverse transcription polymerase chain reaction to detect human metapneumovirus. Three of 126 middle ear specimens were positive by this assay.

  1. CLASSICAL MEDIA RELATIONS AND NEW MEDIA RELATIONS IN SPORT

    Directory of Open Access Journals (Sweden)

    Alexandru Lucian MIHAI

    2014-06-01

    Full Text Available Media relations in sport mean maintenance of networks and positive relationships with people in the media to obtain positive media exposure for a sport product (informal and formal information sessions with media representatives. Because of the pervasive influence the media has on marketing success, sport marketers must make concerted efforts to create a positive relationship between their sport event and the media. They may accomplish this by providing the media with press releases, having news conferences, having media-day events (in which the media are invited to interact with the players, coaches, and administrators, providing media guides for the respective sport events and so on. Each of these activities promotes active involvement from the media, which will subsequently contribute to relationship building with the community.

  2. The comet assay in testing the potential genotoxicity of nanomaterials

    Directory of Open Access Journals (Sweden)

    Amaya Azqueta

    2015-06-01

    Full Text Available In the last two decades the production and use of nanomaterials (NMs has impressively increased. Their small size, given a mass equal to that of the corresponding bulk material, implies an increase in the surface area and consequently in the number of atoms that can be reactive. They possess different physical, chemical and biological properties compared to bulk materials of the same composition, which makes them very interesting and valuable for many different applications in technology, energy, construction, electronics, agriculture, optics, paints, textiles, food, cosmetics, medicine... Toxicological assessment of NMs is crucial; the same properties that make them interesting also make them potentially harmful for health and the environment. However, the term NM covers many different kinds of particle , and so there is no simple, standard approach to assessing their toxicity. NMs can enter the cell, interact with cell components and even penetrate the nucleus and interfere with the genetic material. Among the different branches of toxicology, genotoxicity is a main area of concern since it is closely related with the carcinogenic potential of compounds. The Organisation for Economic Co-operation and Development (OECD has published internationally agreed in vitro and in vivo validated test methods to evaluate different genotoxic endpoints of chemicals, including chromosome and gene mutations, and DNA breaks. However not all the assays are suitable to study the genotoxic potential of NMs as has been shown by the OECD Working Party on Manufactured Nanomaterials (WPMN. Moreover, alterations to DNA bases, which are precursors to mutations and of great importance in elucidating the mechanism of action of NMs, are not covered by the OECD guidelines. The in vivo standard comet assay (which measures DNA breaks and alkali-labile sites was included in the OECD assays battery in September 2014 while the in vitro standard comet assay is currently under

  3. Towards a reconstruction of general bulk metrics

    Science.gov (United States)

    Engelhardt, Netta; Horowitz, Gary T.

    2017-01-01

    We prove that the metric of a general holographic spacetime can be reconstructed (up to an overall conformal factor) from distinguished spatial slices—‘light-cone cuts’—of the conformal boundary. Our prescription is covariant and applies to bulk points in causal contact with the boundary. Furthermore, we describe a procedure for determining the light-cone cuts corresponding to bulk points in the causal wedge of the boundary in terms of the divergences of correlators in the dual field theory. Possible extensions for determining the conformal factor and including the cuts of points outside of the causal wedge are discussed. We also comment on implications for subregion/subregion duality.

  4. Modeling direct interband tunneling. I. Bulk semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Andrew, E-mail: pandrew@ucla.edu [Department of Electrical Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States); Chui, Chi On [Department of Electrical Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States); California NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095 (United States)

    2014-08-07

    Interband tunneling is frequently studied using the semiclassical Kane model, despite uncertainty about its validity. Revisiting the physical basis of this formula, we find that it neglects coupling to other bands and underestimates transverse tunneling. As a result, significant errors can arise at low and high fields for small and large gap materials, respectively. We derive a simple multiband tunneling model to correct these defects analytically without arbitrary parameters. Through extensive comparison with band structure and quantum transport calculations for bulk InGaAs, InAs, and InSb, we probe the accuracy of the Kane and multiband formulas and establish the superiority of the latter. We also show that the nonlocal average electric field should be used when applying either of these models to nonuniform potentials. Our findings are important for efficient analysis and simulation of bulk semiconductor devices involving tunneling.

  5. Multilayer Integrated Film Bulk Acoustic Resonators

    CERN Document Server

    Zhang, Yafei

    2013-01-01

    Multilayer Integrated Film Bulk Acoustic Resonators mainly introduces the theory, design, fabrication technology and application of a recently developed new type of device, multilayer integrated film bulk acoustic resonators, at the micro and nano scale involving microelectronic devices, integrated circuits, optical devices, sensors and actuators, acoustic resonators, micro-nano manufacturing, multilayer integration, device theory and design principles, etc. These devices can work at very high frequencies by using the newly developed theory, design, and fabrication technology of nano and micro devices. Readers in fields of IC, electronic devices, sensors, materials, and films etc. will benefit from this book by learning the detailed fundamentals and potential applications of these advanced devices. Prof. Yafei Zhang is the director of the Ministry of Education’s Key Laboratory for Thin Films and Microfabrication Technology, PRC; Dr. Da Chen was a PhD student in Prof. Yafei Zhang’s research group.

  6. Portable design rules for bulk CMOS

    Science.gov (United States)

    Griswold, T. W.

    1982-01-01

    It is pointed out that for the past several years, one school of IC designers has used a simplified set of nMOS geometric design rules (GDR) which is 'portable', in that it can be used by many different nMOS manufacturers. The present investigation is concerned with a preliminary set of design rules for bulk CMOS which has been verified for simple test structures. The GDR are defined in terms of Caltech Intermediate Form (CIF), which is a geometry-description language that defines simple geometrical objects in layers. The layers are abstractions of physical mask layers. The design rules do not presume the existence of any particular design methodology. Attention is given to p-well and n-well CMOS processes, bulk CMOS and CMOS-SOS, CMOS geometric rules, and a description of the advantages of CMOS technology.

  7. Fully antisymmetrised dynamics for bulk fermion systems

    CERN Document Server

    Vantournhout, Klaas

    2011-01-01

    The neutron star's crust and mantel are typical examples of non-uniform bulk systems with spacial localisations. When modelling such systems at low temperatures, as is the case in the crust, one has to work with antisymmetrised many-body states to get the correct fermion behaviour. Fermionic molecular dynamics, which works with an antisymmetrised product of localised wave packets, should be an appropriate choice. Implementing periodic boundary conditions into the fermionic molecular dynamics formalism would allow the study of the neutron star's crust as a bulk quantum system. Unfortunately, the antisymmetrisation is a non-local entanglement which reaches far out of the periodically repeated unit cell. In this proceeding, we give a brief overview how periodic boundary conditions and fermionic molecular dynamics can be combined without truncating the long-range many-body correlation induced by the antisymmetry of the many-body state.

  8. Bulk and shear viscosity in Hagedorn fluid

    Energy Technology Data Exchange (ETDEWEB)

    Tawfik, A.; Wahba, M. [Egyptian Center for Theoretical Physics (ECTP), MTI University, Faculty of Engineering, Cairo (Egypt)

    2010-11-15

    Assuming that the Hagedorn fluid composed of known particles and resonances with masses m <2 GeV obeys the first-order theory (Eckart) of relativistic fluid, we discuss the transport properties of QCD confined phase. Based on the relativistic kinetic theory formulated under the relaxation time approximation, expressions for bulk and shear viscosity in thermal medium of hadron resonances are derived. The relaxation time in the Hagedorn dynamical fluid exclusively takes into account the decay and eventually van der Waals processes. We comment on the in-medium thermal effects on bulk and shear viscosity and averaged relaxation time with and without the excluded-volume approach. As an application of these results, we suggest the dynamics of heavy-ion collisions, non-equilibrium thermodynamics and the cosmological models, which require thermo- and hydro-dynamics equations of state. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  9. Bulk and Shear Viscosity in Hagedorn Fluid

    CERN Document Server

    Tawfik, A

    2010-01-01

    Assuming that the Hagedorn fluid composed of known particles and resonances with masses $m<2\\,$GeV obeys the {\\it first-order} theory (Eckart) of relativistic fluid, we discuss the transport properties of QCD confined phase. Based on the relativistic kinetic theory formulated under the relaxation time approximation, expressions for bulk and shear viscosity in thermal medium are derived. The relaxation time in the Hagedorn dynamical fluid exclusively takes into account the decay and eventually van der Waals processes. We comment on the {\\it in-medium} thermal effects on bulk and shear viscosities and averaged relaxation time with and without the excluded-volume approach. As an application of these results, we suggest the dynamics of heavy-ion collisions, non-equlibrium thermodynamics and the cosmological models, which require thermo and hydrodynamics equations of state.

  10. Microfabricated bulk wave acoustic bandgap device

    Science.gov (United States)

    Olsson, Roy H.; El-Kady, Ihab F.; McCormick, Frederick; Fleming, James G.; Fleming, Carol

    2010-06-08

    A microfabricated bulk wave acoustic bandgap device comprises a periodic two-dimensional array of scatterers embedded within the matrix material membrane, wherein the scatterer material has a density and/or elastic constant that is different than the matrix material and wherein the periodicity of the array causes destructive interference of the acoustic wave within an acoustic bandgap. The membrane can be suspended above a substrate by an air or vacuum gap to provide acoustic isolation from the substrate. The device can be fabricated using microelectromechanical systems (MEMS) technologies. Such microfabricated bulk wave phononic bandgap devices are useful for acoustic isolation in the ultrasonic, VHF, or UHF regime (i.e., frequencies of order 1 MHz to 10 GHz and higher, and lattice constants of order 100 .mu.m or less).

  11. Media Literacy in Montenegro

    Directory of Open Access Journals (Sweden)

    Jelena Perovic

    2015-12-01

    Full Text Available Few countries in the world have introduced media education into their curriculums. Montenegro became one of them in 2009, when “media literacy” was introduced as an optional subject for 16 and 17 year old students of Gymnasium high schools. This article presents the findings of the first and only research conducted so far on media education in Montenegro. It is a national case study which examines the potential of media education to change the school culture and accelerate education system reform towards embracing the new digital education paradigm in the future. The focus is on the results of research conducted through in-depth interviews with media literacy teachers all over the country. Despite the many challenges, all teachers identify the potential of media education to strengthen some of the key competences of the students and to improve their motivation and academic performance. They also identify potential to change positively school culture by transforming teachers into “cultural mediators” (Morcellini, 2007 and by supporting the formation of a “participative culture” (Jenkins & Kelley, 2013 in schools. This research recommends focusing education reform on spreading the media education pedagogy to the entire curriculum in order to embrace the new digital education paradigm in the future.

  12. Social Media and Bullshit

    Directory of Open Access Journals (Sweden)

    Rasmus Kleis Nielsen

    2015-04-01

    Full Text Available To understand the role of social media in society, we have to understand how social media are understood. We need to analyze how different actors and organizations see and think about technology, the forms of knowledge that people draw on as they make sense of, develop, and use social media. Central among these is bullshit. This short essay discusses bullshit as defined by the philosopher Harry Frankfurt as statements made with little or no concern for their truth-value or justification and argues that social media are accompanied by unusually large amounts of bullshit for two reasons. First, they confront us with epistemological problems and are hard to understand. Second, there is a large demand for knowledge about what they mean, a powerful political economy that generates a lot of statements about social media, including substantial amounts of bullshit. Given the rapid development of social media and their growing importance, this is unlikely to change in the near future. Bullshit is here to stay, and we need to take it seriously intellectually and analytically to understand social media.

  13. Depleted Bulk Heterojunction Colloidal Quantum Dot Photovoltaics

    KAUST Repository

    Barkhouse, D. Aaron R.

    2011-05-26

    The first solution-processed depleted bulk heterojunction colloidal quantum dot solar cells are presented. The architecture allows for high absorption with full depletion, thereby breaking the photon absorption/carrier extraction compromise inherent in planar devices. A record power conversion of 5.5% under simulated AM 1.5 illumination conditions is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. On bulk viscosity and moduli decay

    OpenAIRE

    M. Laine

    2010-01-01

    This pedagogically intended lecture, one of four under the header "Basics of thermal QCD", reviews an interesting relationship, originally pointed out by Bodeker, that exists between the bulk viscosity of Yang-Mills theory (of possible relevance to the hydrodynamics of heavy ion collision experiments) and the decay rate of scalar fields coupled very weakly to a heat bath (appearing in some particle physics inspired cosmological scenarios). This topic serves, furthermore, as a platform on whic...

  15. Depleted bulk heterojunction colloidal quantum dot photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Barkhouse, D.A.R. [Department of Electrical and Computer Engineering, University of Toronto, 10 King' s College Road, Toronto, Ontario M5S 3G4 (Canada); IBM Thomas J. Watson Research Center, Kitchawan Road, Yorktown Heights, NY, 10598 (United States); Debnath, Ratan; Kramer, Illan J.; Zhitomirsky, David; Levina, Larissa; Sargent, Edward H. [Department of Electrical and Computer Engineering, University of Toronto, 10 King' s College Road, Toronto, Ontario M5S 3G4 (Canada); Pattantyus-Abraham, Andras G. [Department of Electrical and Computer Engineering, University of Toronto, 10 King' s College Road, Toronto, Ontario M5S 3G4 (Canada); Quantum Solar Power Corporation, 1055 W. Hastings, Ste. 300, Vancouver, BC, V6E 2E9 (Canada); Etgar, Lioz; Graetzel, Michael [Laboratory for Photonics and Interfaces, Institute of Chemical Sciences and Engineering, School of Basic Sciences, Swiss Federal Institute of Technology, CH-1015 Lausanne (Switzerland)

    2011-07-26

    The first solution-processed depleted bulk heterojunction colloidal quantum dot solar cells are presented. The architecture allows for high absorption with full depletion, thereby breaking the photon absorption/carrier extraction compromise inherent in planar devices. A record power conversion of 5.5% under simulated AM 1.5 illumination conditions is reported. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  16. Effects of bulk viscosity on cosmological evolution

    CERN Document Server

    Pimentel, L O; Pimentel, L O; Diaz-Rivera, L M

    1994-01-01

    Abstract:The effect of bulk viscisity on the evolution of the homogeneous and isotropic cosmological models is considered. Solutions are found, with a barotropic equation of state, and a viscosity coefficient that is proportional to a power of the energy density of the universe. For flat space, power law expansions, related to extended inflation are found as well as exponential solutions, related to old inflation; also a solution with expansion that is an exponential of an exponential of the time is found.

  17. Raman characterization of bulk ferromagnetic nanostructured graphite

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, Helena, E-mail: hpardo@fq.edu.uy [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay); Divine Khan, Ngwashi [Mantfort University, Leicester (United Kingdom); Faccio, Ricardo [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay); Araujo-Moreira, F.M. [Grupo de Materiais e Dispositivos-CMDMC, Departamento de Fisica e Engenharia Fisica, UFSCar, Caixa Postal 676, 13565-905, Sao Carlos SP (Brazil); Fernandez-Werner, Luciana [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay)

    2012-08-15

    Raman spectroscopy was used to characterize bulk ferromagnetic graphite samples prepared by controlled oxidation of commercial pristine graphite powder. The G:D band intensity ratio, the shape and position of the 2D band and the presence of a band around 2950 cm{sup -1} showed a high degree of disorder in the modified graphite sample, with a significant presence of exposed edges of graphitic planes as well as a high degree of attached hydrogen atoms.

  18. Modeling of Microimprinting of Bulk Metallic Glasses

    Institute of Scientific and Technical Information of China (English)

    Ming CHENG; John A. Wert

    2006-01-01

    A finite element analysis (FEA) model has been developed to analyze microimprinting of bulk metallic glasses (BMG) near the glass transition temperature (Tg). The results reveal an approximately universal imprinting response for BMG, independent of surface feature length scale. The scale-independent nature of BMG imprinting derives from the flow characteristics of BMG in the temperature range above Tg. It also shows that the lubrication condition has a mild influence on BMG imprinting in the temperature range above Tg.

  19. Pseudo-Riemannian Universe from Euclidean bulk

    CERN Document Server

    Vasilić, Milovan

    2015-01-01

    I develop the idea that our world is a brane-like object embedded in Euclidean bulk. In its ground state, the brane constituent matter is assumed to be homogeneous and isotropic, and of negligible influence on the bulk geometry. No action functional is initially specified. Instead, the brane dynamics is derived from the universally valid stress-energy conservation equations. The present work studies the cosmology of a $3$-sphere in the $5$-dimensional Euclidean bulk. It is shown that the conventional equation of state $p=\\alpha\\rho$ is universal in the sector of small energy densities, and so is the resulting brane dynamics. The inequality $\\alpha<0$ is found to be a necessary condition for the existence of a stable ground state of the Universe. It is demonstrated that the generic braneworld physics rules out the Big Bang cosmology, and in that matter, any cosmology of finite lifetime. I also demonstrate that stable brane vibrations satisfy Klein-Gordon-like equation with an effective metric of Minkowski s...

  20. Bulk viscous cosmology in early Universe

    Indian Academy of Sciences (India)

    C P Singh

    2008-07-01

    The effect of bulk viscosity on the early evolution of Universe for a spatially homogeneous and isotropic Robertson-Walker model is considered. Einstein's field equations are solved by using `gamma-law' equation of state = ( - 1)ρ, where the adiabatic parameter gamma () depends on the scale factor of the model. The `gamma' function is defined in such a way that it describes a unified solution of early evolution of the Universe for inflationary and radiation-dominated phases. The fluid has only bulk viscous term and the coefficient of bulk viscosity is taken to be proportional to some power function of the energy density. The complete general solutions have been given through three cases. For flat space, power-law as well as exponential solutions are found. The problem of how the introduction of viscosity affects the appearance of singularity, is briefly discussed in particular solutions. The deceleration parameter has a freedom to vary with the scale factor of the model, which describes the accelerating expansion of the Universe.

  1. Bulk Higgs with a heavy diphoton signal

    Science.gov (United States)

    Frank, Mariana; Pourtolami, Nima; Toharia, Manuel

    2017-02-01

    We consider scenarios of warped extra dimensions with all matter fields in the bulk and in which both the hierarchy and the flavor puzzles of the Standard Model are addressed. Inspired by the puzzling excess of diphoton events at 750 GeV reported in the early LHC Run II data (since then understood as a statistical excess), we consider here the general question as to whether the simplest extra-dimensional extension of the Standard Model Higgs sector, i.e., a five-dimensional bulk Higgs doublet, can lead to an intermediate mass resonance (between 500 GeV and 1.5 TeV) of which the first signature would be the presence of diphoton events. This surprising phenomenology can happen if the resonance is the lightest C P -odd state coming from the Higgs sector. No new matter content is required, the only new ingredient being the presence of (positive) brane localized kinetic terms associated to the five-dimensional bulk Higgs (which reduce the mass of the C P -odd states). Production and decay of this resonance can naturally give rise to observable diphoton signals, keeping dijet production under control, with very low ZZ and WW signals and with a highly reduced top pair production in an important region of parameter space. We use the 750 GeV excess as an example case scenario.

  2. Cosmological Implications of QGP Bulk Viscosity

    CERN Document Server

    Anand, Sampurn; Bhatt, Jitesh R

    2016-01-01

    Recent studies of the hot QCD matter indicate that the bulk viscosity ($\\zeta$) of quark-gluon plasma (QGP) rises sharply near the critical point of the QCD phase transition. In this work, we show that such a sharp rise of the bulk viscosity will lead to an effective negative pressure near the critical temperature, $T_{c}$ which in turn drives the Universe to inflate. This inflation has a natural graceful exist when the viscous effect evanesce. We estimate that, depending upon the peak value of $\\zeta$, universe expands by a factor of $10$ to $80$ times in a very short span ($\\Delta t\\sim 10^{-8}$ seconds). Another important outcome of the bulk viscosity dominated dynamics is the cavitation of QGP around $T \\sim 1.5T_{c}$. This would lead to the phenomenon of formation of cavitation bubbles within the QGP phase. The above scenario is independent of the order of QCD phase transition. We delineate some of the important cosmological consequences of the inflation and the cavitation.

  3. Bulk Rashba Semiconductors and Related Quantum Phenomena.

    Science.gov (United States)

    Bahramy, Mohammad Saeed; Ogawa, Naoki

    2017-03-29

    Bithmuth tellurohalides BiTeX (X = Cl, Br and I) are model examples of bulk Rashba semiconductors, exhibiting a giant Rashba-type spin splitting among their both valence and conduction bands. Extensive spectroscopic and transport experiments combined with the state-of-the-art first-principles calculations have revealed many unique quantum phenomena emerging from the bulk Rashba effect in these systems. The novel features such as the exotic inter- and intra-band optical transitions, enhanced magneto-optical response, divergent orbital dia-/para-magnetic susceptibility and helical spin textures with a nontrivial Berry's phase in the momentum space are among the salient discoveries, all arising from this effect. Also, it is theoretically proposed and indications have been experimentally reported that bulk Rashba semiconductors such as BiTeI have the capability of becoming a topological insulator under the application of a hydrostatic pressure. Here, we overview these studies and show that BiTeX are an ideal platform to explore the next aspects of quantum matter, which could ultimately be utilized to create spintronic devices with novel functionalities.

  4. Molecular imprinting of bulk, microporous silica

    Science.gov (United States)

    Katz, Alexander; Davis, Mark E.

    2000-01-01

    Molecular imprinting aims to create solid materials containing chemical functionalities that are spatially organized by covalent or non-covalent interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations, chemical sensing and catalysis. Until now, the molecular imprinting of bulk polymers and polymer and silica surfaces has been reported, but the extension of these methods to a wider range of materials remains problematic. For example, the formation of substrate-specific cavities within bulk silica, while conceptually straightforward, has been difficult to accomplish experimentally. Here we describe the imprinting of bulk amorphous silicas with single aromatic rings carrying up to three 3-aminopropyltriethoxysilane side groups; this generates and occupies microporosity and attaches functional organic groups to the pore walls in a controlled fashion. The triethoxysilane part of the molecules' side groups is incorporated into the silica framework during sol-gel synthesis, and subsequent removal of the aromatic core creates a cavity with spatially organized aminopropyl groups covalently anchored to the pore walls. We find that the imprinted silicas act as shape-selective base catalysts. Our strategy can be extended to imprint other functional groups, which should give access to a wide range of functionalized materials.

  5. Evidence for Bulk Ripplocations in Layered Solids

    Science.gov (United States)

    Gruber, Jacob; Lang, Andrew C.; Griggs, Justin; Taheri, Mitra L.; Tucker, Garritt J.; Barsoum, Michel W.

    2016-09-01

    Plastically anisotropic/layered solids are ubiquitous in nature and understanding how they deform is crucial in geology, nuclear engineering, microelectronics, among other fields. Recently, a new defect termed a ripplocation–best described as an atomic scale ripple–was proposed to explain deformation in two-dimensional solids. Herein, we leverage atomistic simulations of graphite to extend the ripplocation idea to bulk layered solids, and confirm that it is essentially a buckling phenomenon. In contrast to dislocations, bulk ripplocations have no Burgers vector and no polarity. In graphite, ripplocations are attracted to other ripplocations, both within the same, and on adjacent layers, the latter resulting in kink boundaries. Furthermore, we present transmission electron microscopy evidence consistent with the existence of bulk ripplocations in Ti3SiC2. Ripplocations are a topological imperative, as they allow atomic layers to glide relative to each other without breaking the in-plane bonds. A more complete understanding of their mechanics and behavior is critically important, and could profoundly influence our current understanding of how graphite, layered silicates, the MAX phases, and many other plastically anisotropic/layered solids, deform and accommodate strain.

  6. Analysis of bacterial community in bulking sludge using culture-dependent and -independent approaches

    Institute of Scientific and Technical Information of China (English)

    Decai Jin; Ping Wang; Zhihui Bai; Xinxin Wang; Hong Peng; Rong Qi; Zhisheng Yu; Guoqiang Zhuang

    2011-01-01

    The bacterial community of a bulking sludge from a municipal wastewater treatment plant with anoxic-anaerobic-oxic process was investigated by combination of cultivation and 16S rRNA gene clone library analysis for understanding the causes of bulking.A total of 28 species were obtained from 63 isolates collected from six culture media.The most cultivable species belonged to γ-Proteobacteria including Klebsiella sp.,Pseudomonas sp.,Aeromonas sp.and Acinetobacter sp.Further analysis of these strains by repetitive sequence based on polymerase chain reaction (rep-PCR) technology showed that rep-PCR yielded discriminatory banding patterns within the same genus using REP and BOX primer sets.While the culture-independent assessment revealed that β-Proteobacteria was the dominant group in the bulking sample.Sequence analysis revealed that the highest proportion (14.7%) of operational taxonomic units was 98% similar to Candidatus Accumulibacter phosphatis,which is used to remove phosphorous from wastewater.Our results indicated that combining different approaches can produce complementary information,thus generate a more accurate view of microbial community in bulking sludge.

  7. BulkTree: an overlay network architecture for live media streaming

    Institute of Scientific and Technical Information of China (English)

    GONG An; DING Gui-guang; DAI Qiong-hai; LIN Chuang

    2006-01-01

    Peer-to-peer (P2P) systems are now very popular. Current P2P systems are broadly of two kinds, structured and unstructured. The tree structured P2P systems used technologies such as distributed hash tables (DHT) and hierarchical clustering can search the required target quickly, however, in a tree, the internal node has a higher load and its leave or crash often causes a large population of its offspring's problems, so that in the highly dynamic Internet environment the tree structure may still suffer frequent breaks. On the other hand, most widely used unstructured P2P networks rely on central directory servers or massive message flooding, clearly not scalable. So, we consider both of the above systems' advantages and disadvantages and realize that in the P2P systems one node may fail easily, but that when a number of nodes organized as a set, which we call "super node", the set is robust. Super nodes can be created and updated aware of topology-aware, and used with simple protocol such as flooding or "servers" to exchange information. Furthermore the entire robust super node can be organized into exquisite tree structure. By using this overlay network architecture, P2P systems are robust, efficient, scalable and secure. The simulation results demonstrated that our architecture greatly reduces the alteration time of the structure while decreasing the average delay time, compared to the common tree structure.

  8. Social Media and Bullshit

    OpenAIRE

    2015-01-01

    To understand the role of social media in society, we have to understand how social media are understood. We need to analyze how different actors and organizations see and think about technology, the forms of knowledge that people draw on as they make sense of, develop, and use social media. Central among these is bullshit. This short essay discusses bullshit as defined by the philosopher Harry Frankfurt as statements made with little or no concern for their truth-value or justification and a...

  9. Ethics and social media.

    Science.gov (United States)

    Milton, Constance L

    2014-10-01

    Nurses' use of social media has increased significantly with growing numbers of media-sharing opportunities, platforms, and emerging forms of electronic applications. With the proliferation, opportunities and limitations surface regarding the responsibilities and accountability that nurses have in choosing technology applications with an embedded philosophical ethos that is consistent with the discipline's societal mandate of serving humankind in ways that honor human dignity. This article begins a discussion addressing possible disciplinary obligations and responsibilities for the implementation of social media platforms and possible implications for its future use in the discipline of nursing.

  10. Open Media Science

    DEFF Research Database (Denmark)

    Møller Moltke Martiny, Kristian; Pedersen, David Budtz; Hansted, Allan Alfred Birkegaard

    2016-01-01

    In this article, we present three challenges to the emerging Open Science (OS) movement: the challenge of communication, collaboration and cultivation of scientific research. We argue that to address these challenges OS needs to include other forms of data than what can be captured in a text...... and extend into a fully-fledged Open Media movement engaging with new media and non-traditional formats of science communication. We discuss two cases where experiments with open media have driven new collaborations between scientists and documentarists. We use the cases to illustrate different advantages...

  11. Media violence and youth.

    Science.gov (United States)

    Beresin, E V

    1999-06-01

    This column reviews the literature on violence in the media and its effects on youth. The author summarizes the findings of naturalistic, longitudinal, and population-based studies conducted over the last 30 years. The literature provides compelling evidence that exposure of media violence to children plays a major role in the etiology of aggressive behavior. Psychiatrists can facilitate primary prevention of violence in our society by discussing the problem of media violence with parents, medical students, residents, and allied health and school professionals.

  12. A nylon membrane bag assay for determination of the effect of chemicals on soilborne plant pathogens in soil

    Science.gov (United States)

    A new nylon membrane bag assay was developed that can rapidly and effectively determine the impact of chemicals added to soil on soilborne plant pathogens for which there are no selective media or for which a selective medium is expensive or difficult to prepare. This assay consists of placing patho...

  13. Practical assay issues with the PERT/PBRT assay: a highly sensitive reverse transcriptase assay.

    Science.gov (United States)

    Chang, A; Dusing, S

    2006-01-01

    Product safety testing for retroviruses can be achieved by a panel of screening assays, including electron microscopy, viral gene specific PCRs, virus propagation, and detection of reverse transciptase activity. The application of PCR-based reverse transcriptase assays (PERT) that are approximately a million-fold more sensitive than conventional nucleotide incorporation assays in the testing of biologicals is described. Use of PERT assays can be applied to three areas: (i) screening for adventitious retrovirus contamination; (ii) detecting and quantifying endogenous viral particle load and (iii) monitoring levels of infectious retrovirus generation in cell lines that contain endogenous retroviruses.

  14. Stable helical solitons in optical media

    Indian Academy of Sciences (India)

    Boris Malomed; G D Peng; P L Chu; Isaac Towers; Alexander V Buryak; Rowland A Sammut

    2001-11-01

    We present a review of new results which suggest the existence of fully stable spinning solitons (self-supporting localised objects with an internal vorticity) in optical fibres with self-focusing Kerr (cubic) nonlinearity, and in bulk media featuring a combination of the cubic self-defocusing and quadratic nonlinearities. Their distinctive difference from other optical solitons with an internal vorticity, which were recently studied in various optical media, theoretically and also experimentally, is that all the spinning solitons considered thus far have been found to be unstable against azimuthal perturbations. In the first part of the paper, we consider solitons in a nonlinear optical fibre in a region of parameters where the fibre carries exactly two distinct modes, viz., the fundamental one and the first-order helical mode. From the viewpoint of application to communication systems, this opens the way to doubling the number of channels carried by a fibre. Besides that, these solitons are objects of fundamental interest. To fully examine their stability, it is crucially important to consider collisions between them, and their collisions with fundamental solitons, in (ordinary or hollow) optical fibres. We introduce a system of coupled nonlinear Schrödinger equations for the fundamental and helical modes with nonstandard values of the cross-phase-modulation coupling constants, and show, in analytical and numerical forms, results of collisions between solitons carried by the two modes. In the second part of the paper, we demonstrate that the interaction of the fundamental beam with its second harmonic in bulk media, in the presence of self-defocusing Kerr nonlinearity, gives rise to the first ever example of completely stable spatial ring-shaped solitons with intrinsic vorticity. The stability is demonstrated both by direct simulations and by analysis of linearized equations.

  15. Tailoring Magnetic Properties in Bulk Nanostructured Solids

    Science.gov (United States)

    Morales, Jason Rolando

    Important magnetic properties and behaviors such as coercivity, remanence, susceptibility, energy product, and exchange coupling can be tailored by controlling the grain size, composition, and density of bulk magnetic materials. At nanometric length scales the grain size plays an increasingly important role since magnetic domain behavior and grain boundary concentration determine bulk magnetic behavior. This has spurred a significant amount of work devoted to developing magnetic materials with nanometric features (thickness, grain/crystallite size, inclusions or shells) in 0D (powder), 1D (wires), and 2D (thin films) materials. Large 3D nanocrystalline materials are more suitable for many applications such as permanent magnets, magneto-optical Faraday isolators etc. Yet there are relatively few successful demonstrations of 3D magnetic materials with nanoscale influenced properties available in the literature. Making dense 3D bulk materials with magnetic nanocrystalline microstructures is a challenge because many traditional densification techniques (HIP, pressureless sintering, etc.) move the microstructure out of the "nano" regime during densification. This dissertation shows that the Current Activated Pressure Assisted Densification (CAPAD) method, also known as spark plasma sintering, can be used to create dense, bulk, magnetic, nanocrystalline solids with varied compositions suited to fit many applications. The results of my research will first show important implications for the use of CAPAD for the production of exchange-coupled nanocomposite magnets. Decreases in grain size were shown to have a significant role in increasing the magnitude of exchange bias. Second, preferentially ordered bulk magnetic materials were produced with highly anisotropic material properties. The ordered microstructure resulted in changing magnetic property magnitudes (ex. change in coercivity by almost 10x) depending on the relative orientation (0° vs. 90°) of an externally

  16. Flute-Model Acoustic Metamaterials with Simultaneously Negative Bulk Modulus and Mass Density

    CERN Document Server

    Zeng, H C; Chen, H J; Zhai, S L; Zhao, X P

    2012-01-01

    We experimentally constructed a three-dimensional flute-model "molecular" structure acoustic metamaterial(AM)from a periodic array of perforated hollow steel tubes (PHSTs) and investigated its transmission and reflection behaviors in impedance tube system. The AM exhibited a transmission peak and an inverse phase, thus exhibiting the local resonance of the PHSTs. Based on the homogeneous media theory, the effective bulk modulus and mass density of the AM were calculated to be simultaneously negative; the refractive index was also negative. PHST AM slab focusing experiments showed that the medium with a resonant structure exhibited a distinct metamaterial property.

  17. Accurate bulk density determination of irregularly shaped translucent and opaque aerogels

    Science.gov (United States)

    Petkov, M. P.; Jones, S. M.

    2016-05-01

    We present a volumetric method for accurate determination of bulk density of aerogels, calculated from extrapolated weight of the dry pure solid and volume estimates based on the Archimedes' principle of volume displacement, using packed 100 μm-sized monodispersed glass spheres as a "quasi-fluid" media. Hard particle packing theory is invoked to demonstrate the reproducibility of the apparent density of the quasi-fluid. Accuracy rivaling that of the refractive index method is demonstrated for both translucent and opaque aerogels with different absorptive properties, as well as for aerogels with regular and irregular shapes.

  18. Cooling flow bulk motion corrections to the Sunyaev Zel'dovich effect

    CERN Document Server

    Koch, P M; Puy, D; Jetzer, Ph.

    2002-01-01

    We study the influence of converging cooling flow bulk motions on the Sunyaev-Zel'dovich (SZ) effect. To that purpose we derive a modified Kompaneets equation which takes into account the contribution of the accelerated electron media of the cooling flow inside the cluster frame. The additional term is different from the usual kinematic SZ-effect, which depends linearly on the velocity, whereas the contribution described here is quadratic in the macroscopic electron fluid velocity, as measured in the cluster frame. For clusters with a large cooling flow mass deposition rate and/or a small central electron density, it turns out that this effect becomes relevant.

  19. Media and ICT

    DEFF Research Database (Denmark)

    Media and information and communication technologies (ICTs) have in the past decades been placed firmly on the educational agenda, and will continue to maintain this position, not least as catalysts for educational change. This issue is reflected in the anthology as it aims to respond to the ques......Media and information and communication technologies (ICTs) have in the past decades been placed firmly on the educational agenda, and will continue to maintain this position, not least as catalysts for educational change. This issue is reflected in the anthology as it aims to respond...... to the question of how the presence of media and ICT in and outside schools both change and qualify educational practice as well as how the cooperation between media, cultures, aesthetics and social relations affect and support new demands on education. The book represents different academic perspectives...

  20. Media and Security Team

    Data.gov (United States)

    Federal Laboratory Consortium — The Media And Security Team led by Prof. Min Wu was established in Fall 2001 at University of Maryland, College Park. A number of research and education activities...

  1. Media Challenging Status Quo

    DEFF Research Database (Denmark)

    Sandvik, Kjetil

    Digital media and especially so-called ‘social media’ have on the one hand been ascribed the power to change societies and empower democratic movements following the thoughts of e.g. Rheingold (2004), recently fueled by the democratic uprising in Arabic countries such as Egypt, Tunisia, Iran...... and Libya creating headlines like “the Facebook revolution”. On the other hand, several scholars argue that it is naive to believe that social media in themselves create change: they may at the best facilitate already existing social and political movements (Downing 2008, Christakis & Fowler 2010......). Skeptical internet sociologists such as Morozov (2011) point out that the same media which was used e.g. to mobilize the ‘Twitter revolution’ in Iran in 2009 also was used by the regime to infiltrate and strike down the democratic movement. Following such position statements, international media...

  2. Spotlight on the media

    CERN Multimedia

    2007-01-01

    Do you want to know more about how the media works, how to deal with journalists? How to maximise opportunity and minimise threat? Then please join us on 22 November. This session will cover how to work effectively with the media, including print, radio and TV. You’ll get an insight into how journalists and news rooms operate. You’ll learn to recognise both soft balls and traps - and develop the techniques for dealing with them. The challenges of explaining CERN to any media outlet will be dealt with too. This interactive presentation, given by Jessica Pryce-Jones, Managing Director of the consultancy firm iOpener Ltd, and Nisha Pillai, news anchor for BBC World, will be illustrated with various case studies. How to deal with the media: maximising opportunity and minimising threat Thursday 22 November, from 4.30 pm, Main Auditorium, Bldg. 500 Coffee break before the event at 4.00 pm

  3. Functionally Graded Media

    OpenAIRE

    Campos, Cédric M.; Epstein, Marcelo; De León, Manuel

    2007-01-01

    The notions of uniformity and homogeneity of elastic materials are reviewed in terms of Lie groupoids and frame bundles. This framework is also extended to consider the case Functionally Graded Media, which allows us to obtain some homogeneity conditions.

  4. Stochastic porous media equations

    CERN Document Server

    Barbu, Viorel; Röckner, Michael

    2016-01-01

    Focusing on stochastic porous media equations, this book places an emphasis on existence theorems, asymptotic behavior and ergodic properties of the associated transition semigroup. Stochastic perturbations of the porous media equation have reviously been considered by physicists, but rigorous mathematical existence results have only recently been found. The porous media equation models a number of different physical phenomena, including the flow of an ideal gas and the diffusion of a compressible fluid through porous media, and also thermal propagation in plasma and plasma radiation. Another important application is to a model of the standard self-organized criticality process, called the "sand-pile model" or the "Bak-Tang-Wiesenfeld model". The book will be of interest to PhD students and researchers in mathematics, physics and biology.

  5. Consolidating Social Media Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Munar, Ana Maria; Larson, Mia

    2014-01-01

    This study revisits and integrates the insights of recent studies on emergent social media strategies deployed by destination and event management organisations. In a comparative analysis Munar (2012) identified four generic approaches pursued by national tourism boards in the Nordic region, while...... Gyimóthy & Larson (2014) portrayed three digital value co-creation strategies deployed by festival social media. Both frameworks provided novel analytical typologies which identified a series of categories (mimetic, analytic, immersion, advertising and insourcing, crowdsourcing and community consolidation......). This paper discusses the complementary nature of these conceptual proposals and advances an integrated conceptual framework of social media strategies. Based on the empirical findings of a case study that revisits evolving digital and social media strategies of European DMOs this paper maps the dynamics...

  6. Media studies for scientists

    CERN Multimedia

    2002-01-01

    "Science, with its inherent uncertainties, can be hard to put across to the public. But blaming 'sloppy' journalism is too easy. If researchers are to make their points effectively, they should learn more about how the media work" (1 page).

  7. Research in Learning Media

    NARCIS (Netherlands)

    Westera, Wim

    2009-01-01

    Westera, W. (2009). Research in Learning Media, CELSTEC lab. Presentation on behalf of a delegation of Teleac/NOT and the scientific board of the Veringa chair. February, 13, 2009, Heerlen, The Netherlands: Open University of the Netherlands.

  8. Mixed-Media Owls

    Science.gov (United States)

    Schultz, Kathy

    2010-01-01

    The fun of creating collages is there are unlimited possibilities for the different kinds of materials one can use. In this article, the author describes how her eighth-grade students created an owl using mixed media.

  9. Social Media and Teaching

    DEFF Research Database (Denmark)

    Tække, Jesper; Paulsen, Michael

    New research in the Danish upper secondary schools shows that social media like Facebook is the number one attention diverts from the interaction about educational subjects in the classroom. At the same time international research shows that there is a great potential in using social media....... The overriding purpose of the paper is to provide a research-based input to the discussion about the role of social media in schools....... the past seven years (Paulsen & Tække 2009, 2010; Tække & Paulsen 2010). To find out if and how the gap can be reduced, we have initiated the action research project The Socio Media Education Experiment, and in the paper we explain both the background for the project and its preliminary results...

  10. Subsidizing Media Innovation

    DEFF Research Database (Denmark)

    Kammer, Aske; Hobel, Emil

    ). Qualitative Media Analysis (2nd Ed.). Los Angeles: Sage. Esping-Andersen, G. (1990). The Three Worlds of Welfare Capitalism. Cambridge: Polity Press. Kammer, A. (forthcoming/2016). Market Structure and Innovation Policies in Denmark. In H. v. Kranenburg (Ed.), Innovation Policies in the European News......When the Danish Parliament revised the media-subsidy framework in 2013/2014, one of the new initiatives was the introduction of a pool of funding earmarked to establishing and developing new news media – the so-called “innovation fund”. So, as the news industry struggles to keep journalism a viable...... and economically sustainable activity, the institutionalization of financial support for media innovation constitute one way for policy makers to bring (parts of) the journalistic environment up-to-date with the digital age, thereby improving the conditions for an informed citizenry in the future (Kammer...

  11. TECHNETIUM SORPTION MEDIA REVIEW

    Energy Technology Data Exchange (ETDEWEB)

    DUNCAN JB; KELLY SE; ROBBINS RA; ADAMS RD; THORSON MA; HAASS CC

    2011-08-25

    This report presents information and references to aid in the selection of 99Tc sorption media for feasibility studies regarding the removal of 99Tc from Hanford's low activity waste. The report contains literature search material for sorption media (including ion exchange media) for the most tested media to date, including SuperLig 639, Reillex HPQ, TAM (Kruion), Purolite A520E and A530E, and Dowex 1X8. The U.S. Department of Energy (DOE), Office of River Protection (ORP) is responsible for management and completion of the River Protection Project (RPP) mission, which comprises both the Hanford Site tank farms and the Waste Treatment and Immobilization Plant (WTP). The RPP mission is to store, retrieve and treat Hanford's tank waste; store and dispose of treated wastes; and close the tank farm waste management areas and treatment facilities in a safe, environmentally compliant, cost-effective and energy-effective manner.

  12. Social Media Cocreation Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Larson, Mia

    2015-01-01

    This paper explores how social media becomes a part of integrated marketing communications of festival organizations. The purpose of this paper is to conceptualize the co-creation of festival experiences online by comparing managerial strategies and communicative patterns of three large....... Based on the empirical findings, we propose an analytical framework to improve our understanding of the management of social media communications, offering three distinct value co-creation strategies in a festival context....

  13. On commercial media bias

    OpenAIRE

    Germano, Fabrizio

    2008-01-01

    Within the spokes model of Chen and Riordan (2007) that allows for non-localized competition among arbitrary numbers of media outlets, we quantify the effect of concentration of ownership on quality and bias of media content. A main result shows that too few commercial outlets, or better, too few separate owners of commercial outlets can lead to substantial bias in equilibrium. Increasing the number of outlets (commercial and non-commercial) tends to bring down this bias; but the strongest ef...

  14. Drupal 7 media

    CERN Document Server

    Tal, Liran

    2013-01-01

    This is a practical, hands-on guide packed with examples that will help you build rich Drupal 7 media web applications.If you are a Drupal site builder and you wish to spice up your web applications with rich media content, then this book is for you. A basic understanding of HTML, JavaScript, and basic PHP module development in Drupal would be helpful, but is not necessary.

  15. Digital Media Ethics

    DEFF Research Database (Denmark)

    Ess, Charles

    Provides a philosophical-ethical "toolkit" for analyzing central ethical issues evoked by our use of new media, including privacy, copyright, violent and sexual content online, and cross-cultural communication online.......Provides a philosophical-ethical "toolkit" for analyzing central ethical issues evoked by our use of new media, including privacy, copyright, violent and sexual content online, and cross-cultural communication online....

  16. The social media image

    Directory of Open Access Journals (Sweden)

    Nadav Hochman

    2014-08-01

    Full Text Available How do the organization and presentation of large-scale social media images recondition the process by which visual knowledge, value, and meaning are made in contemporary conditions? Analyzing fundamental elements in the changing syntax of existing visual software ontology—the ways current social media platforms and aggregators organize and categorize social media images—this article relates how visual materials created within social media platforms manifest distinct modes of knowledge production and acquisition. First, I analyze the structure of social media images within data streams as opposed to previous information organization in a structured database. While the database has no pre-defined notions of time and thus challenges traditional linear forms, the data stream re-emphasizes the linearity of a particular data sequence and activates a set of new relations to contemporary temporalities. Next, I show how these visual arrangements and temporal principles are manifested and discussed in three artworks: “Untitled” (Perfect Lovers by Felix Gonzalez-Torres (1991, The Clock by Christian Marclay (2011, and Last Clock by Jussi Ängeslevä and Ross Cooper (2002. By emphasizing the technical and poetic ways in which social media situate the present as a “thick” historical unit that embodies multiple and synchronous temporalities, this article illuminates some of the conditions, challenges, and tensions between former visual structures and current ones, and unfolds the cultural significations of contemporary big visual data.

  17. Media, risk and science

    CERN Document Server

    Allan, Stuart

    2002-01-01

    How is science represented by the media? Who defines what counts as a risk, threat or hazard, and why? In what ways do media images of science shape public perceptions? What can cultural and media studies tell us about current scientific controversies? "Media, Risk and Science" is an exciting exploration into an array of important issues, providing a much needed framework for understanding key debates on how the media represent science and risk. In a highly effective way, Stuart Allan weaves together insights from multiple strands of research across diverse disciplines. Among the themes he examines are: the role of science in science fiction, such as "Star Trek"; the problem of 'pseudo-science' in "The X-Files"; and how science is displayed in science museums. Science journalism receives particular attention, with the processes by which science is made 'newsworthy' unravelled for careful scrutiny. The book also includes individual chapters devoted to how the media portray environmental risks, HIV-AIDS, food s...

  18. Otitis media: conceptos actuales

    Directory of Open Access Journals (Sweden)

    Hernán Sierra Fernández

    2004-09-01

    Full Text Available La otitis media aguda es uno de los motivos más frecuentes de consulta en la edad pediátrica. Los gérmenes que con mayor frecuencia se aíslan en el oído medio de estos pacientes son el Streptococcus pneumoniae, el Haemophilus influenzae, la Moraxella catarrhalis y el Streptococcus pyogenes. El patrón de resistencia antibiótica de estas bacterias varía dependiendo de la región geográfica. y es la base fundamental para establecer recomendaciones terapéuticas. El análisis en Costa Rica. de la microbiología de la otitis media aguda, otitis media recurrente y otitis media catalogada como falla terapéutica, sugiere que la amoxicilina en una dosis de 50 mg/Kg/día por 10 días, debe ser considerada el antibiótico de primera línea en los casos de otitis media aguda. En los pacientes con otitis media recurrente, falla antimicrobiana o cuando se sospeche la presencia de un Streptococcus pneumoniae resistente a la penicilina, se debe considerar el uso de amoxicilina en dosis más elevadas, amoxicilina con ácido clavulánico, macrólidos o ceftrlaxona.

  19. Self-media

    DEFF Research Database (Denmark)

    Fausing, Bent

    2015-01-01

    The self and identity are not only topics related to the selfies. They are connected to the development of media since the renaissance, the self-media. This is the thesis of the following. The subject, the self, is most clearly exposed in the face, and face and identity becomes important in the m......The self and identity are not only topics related to the selfies. They are connected to the development of media since the renaissance, the self-media. This is the thesis of the following. The subject, the self, is most clearly exposed in the face, and face and identity becomes important...... in the media since the renaissance. The selfies is just the newest development is this tradition, which began with the invention of the mirror, the book (printing), and the small painting. They all put the subject as both maker and receiver in the center. It was the beginning of the modern subject....... The development continued throughout the coming centuries. The selfies is the newest creation to discover, explore, visualize and find the self of the subject. The following will thus emphasis the self, the face, where the self is most noticeably expressed and seen, and the self-media, where the individual can...

  20. Mixed-Media File Systems

    NARCIS (Netherlands)

    Bosch, Hendrikus Gerardus Petrus

    1999-01-01

    This thesis addresses the problem of implementing mixed-media storage systems. In this work a mixed-media file system is defined to be a system that stores both conventional (best-effort) file data and real-time continuous-media data. Continuous-media data is usually bulky, and servers storing and r

  1. Advertising media selection and planning

    NARCIS (Netherlands)

    Moorman, M.; Neijens, P.C.; Smit, E.G.; Belch, M.A.; Belch, G.E.

    2010-01-01

    Reach, frequency, and timing are key concepts in selecting TV, radio, newspapers, magazines, out-of-home, direct mail, Internet, and other media for advertising campaigns. We discuss these concepts and their role in media selection and media planning processes. We also describe media and audience fa

  2. Transporter assays and assay ontologies: useful tools for drug discovery.

    Science.gov (United States)

    Zdrazil, Barbara; Chichester, Christine; Zander Balderud, Linda; Engkvist, Ola; Gaulton, Anna; Overington, John P

    2014-06-01

    Transport proteins represent an eminent class of drug targets and ADMET (absorption, distribution, metabolism, excretion, toxicity) associated genes. There exists a large number of distinct activity assays for transport proteins, depending on not only the measurement needed (e.g. transport activity, strength of ligand–protein interaction), but also due to heterogeneous assay setups used by different research groups. Efforts to systematically organize this (divergent) bioassay data have large potential impact in Public-Private partnership and conventional commercial drug discovery. In this short review, we highlight some of the frequently used high-throughput assays for transport proteins, and we discuss emerging assay ontologies and their application to this field. Focusing on human P-glycoprotein (Multidrug resistance protein 1; gene name: ABCB1, MDR1), we exemplify how annotation of bioassay data per target class could improve and add to existing ontologies, and we propose to include an additional layer of metadata supporting data fusion across different bioassays.

  3. The Romanian Media - An Overview

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available The Romanian Media Sector from the last 17 years can be described as a dinamic one. In the current study, which is also a part of national report of the Grundtvig 2 project "The Influence of Media in Adult Education Development" 06-G2-94-TM-RO-C, we divided the media sector into: printed media, audio-visual media, media based on web and new media. Within this article, I tried to present a short history, state of the art, as well as the tendencies on short term, for each of them.

  4. Stress degradation studies on betahistine and development of a validated stability-indicating assay method.

    Science.gov (United States)

    Khedr, Alaa; Sheha, Mahmoud

    2008-06-15

    The purpose of this work was to study the stability of betahistine (BET) at different stress conditions and to develop a sensitive stability-indicating high-performance liquid chromatographic (HPLC) assay method. The stress conditions applied were including the effect of heat, moisture, acid-base, and ultra-violet (UV) light. Betahistine and its decomposition products were derivatized by reaction with dansyl chloride (Dan-Cl) and analyzed by HPLC equipped with fluorescence detector (FL) set at 336 and 531 nm as excitation and emission wavelengths, respectively. The drug was particularly labile at UV light and oxygen rich media. Two potential degradation products could be separated and identified by spectral methods. The chromatographic method involved Zorbax Eclipse XDB-C(18) column kept at 30+/-2 degrees C and a gradient elution with mobile phase composed of acetonitrile and 0.02 mol L(-1) sodium acetate. The response factor of dansylated BET monitored by fluorescence detection was 32 times more than its UV response. The calibration curve of BET in bulk form was linear from 0.005 to 4.2 ng microL(-1). Intraday and interday precision were less than 0.04% (CV), and accuracy was between 99.2% and 100.9% over 2.0 ng microL(-1). The limit of detection was 0.002 ng microL(-1). The method was also validated for sample stability during reaction, robustness and selectivity. The method was applied for purity testing of betahistine in tablet form.

  5. A Compton Suppressed Gamma Ray Counter For Radio Assay of Materials

    Science.gov (United States)

    Godfrey, Benjamin

    2016-03-01

    Rare event searches, such as direct dark matter experiments, require materials with ultra-low levels of natural radioactivity. We present a neutron activation analysis (NAA) technique for assaying metals, specifically titanium used for cryostat construction. Earlier attempts at NAA encountered limitations due to bulk activation via (n, p) reactions, which contributed to large continuum backgrounds due to Compton tails. Our method involves a heavy water shielded exposure to minimize (n,p) reactions and a sodium iodide shielded high purity germanium counter for the gamma ray assay. Preliminary results on assays for U/Th/K contamination in titaniumwill be presented.

  6. Materials for Bulk Acoustic Resonators and Filters

    Science.gov (United States)

    Loebl, Hans-Peter

    2003-03-01

    Highly selective solidly mounted bulk acoustic wave (BAW) band pass filters are suited for mobile and wireless systems in the GHz frequency range between 0.8 and 10 GHz. Electro-acoustic thin film BAW resonators are the building blocks these BAW filters. Piezoelectric materials used in these resonators include mainly AlN or ZnO which can be deposited by dedicated thin film sputter deposition techniques. Using these piezo-electric materials and using suited materials for the acoustic Bragg reflector, BAW resonators with high quality factors can be fabricated. The achievable filter bandwidth is approximately 4Alternatively, also ferroelectric thin films might be used to achieve higher coupling coefficient and thus filter bandwidth. BAW resonators and filters have been designed and fabricated on 6" Silicon and glass wafers. Results are presented for resonators and filters operating between 1.95 and 8 GHz. The talk will give an overview of the material aspects which are important for BAW devices. It will be shown that modeling of the resonator and filter response using 1D electro-acoustic simulation (1,2) which includes losses is essential to extract acoustic and electrical material parameters. (1) Solidly Mounted Bulk Acoustic Wave Filters for the Ghz Frequency Range, H.P. Loebl, C. Metzmacher , D.N.Peligrad , R. Mauczok , M. Klee , W. Brand , R.F. Milsom , P.Lok , F.van Straten , A. Tuinhout , J.W.Lobeek, IEEE 2002 Ultrasonics Symposium Munich, October 2002. (2) Combined Acoustic-Electromagnetic Simulation Of Thin-Film Bulk Acoustic Wave Filters, R.F. Milsom, H-P. Löbl, D.N. Peligrad, J-W. Lobeek, A. Tuinhout, R. H. ten Dolle IEEE 2002 Ultrasonics Symposium Munich, October 2002.

  7. Otitis media: conceptos actuales

    Directory of Open Access Journals (Sweden)

    Hernán Sierra Fernández

    2004-09-01

    Full Text Available La otitis media aguda es uno de los motivos más frecuentes de consulta en la edad pediátrica. Los gérmenes que con mayor frecuencia se aíslan en el oído medio de estos pacientes son el Streptococcus pneumoniae, el Haemophilus influenzae, la Moraxella catarrhalis y el Streptococcus pyogenes. El patrón de resistencia antibiótica de estas bacterias varía dependiendo de la región geográfica. y es la base fundamental para establecer recomendaciones terapéuticas. El análisis en Costa Rica. de la microbiología de la otitis media aguda, otitis media recurrente y otitis media catalogada como falla terapéutica, sugiere que la amoxicilina en una dosis de 50 mg/Kg/día por 10 días, debe ser considerada el antibiótico de primera línea en los casos de otitis media aguda. En los pacientes con otitis media recurrente, falla antimicrobiana o cuando se sospeche la presencia de un Streptococcus pneumoniae resistente a la penicilina, se debe considerar el uso de amoxicilina en dosis más elevadas, amoxicilina con ácido clavulánico, macrólidos o ceftrlaxona.Otitis media is one of the most common causes of consultation among the pediatric population. The pathogens most frequently isolated from middle ear fluid are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Antimicrobial resistance patterns vary by region and their knowledge is considered important in order to achieve proper antimicrobial selection. In Costa Rica the microbiology of patients with acute, recurrent and tteattnent failure otitis media has been recently analyzed. The results of these studies indicate that amoxicillin at 50 mg/kg/day for 10 days should be considered first line of therapy for patients with acute otitis media. In patients with recurrent otitis media, therapeutic failures or in patients at risk of having a penicillin non-susceptible Streptococcus pneumoniae, one of the second line agents should be considered.

  8. Mediatization Theory and Digital Media

    DEFF Research Database (Denmark)

    Finnemann, Niels Ole

    2011-01-01

    of application.  In Section Two the paper discusses different conceptualizations. It is argued that even if they bring new insights, they cannot be unified into one concept, and that they also lack a consistent definition of digital media. Section three provides a definition of digital media in order to identify...... new trajectories made possible by these media, which have led into a new media matrix built around the internet and mobile devices. It will be argued that the new media matrix cannot be understood from a point of view defined by the framework of 20th century mass media because digital media open new......In the 20th century, the term "media logic" was introduced to denote the influence of independent mass media on political systems and other institutions. In recent years the idea has been reworked and labelled "mediatization" to widen the framework by including new media and new areas...

  9. Improving the bulk data transfer experience

    Energy Technology Data Exchange (ETDEWEB)

    Guok, Chin; Guok, Chin; Lee, Jason R.; Berket, Karlo

    2008-05-07

    Scientific computations and collaborations increasingly rely on the network to provide high-speed data transfer, dissemination of results, access to instruments, support for computational steering, etc. The Energy Sciences Network is establishing a science data network to provide user driven bandwidth allocation. In a shared network environment, some reservations may not be granted due to the lack of available bandwidth on any single path. In many cases, the available bandwidth across multiple paths would be sufficient to grant the reservation. In this paper we investigate how to utilize the available bandwidth across multiple paths in the case of bulk data transfer.

  10. Binary Cu-Zr Bulk Metallic Glasses

    Institute of Scientific and Technical Information of China (English)

    TANG Mei-Bo; ZHAO De-Qian; PAN Ming-Xiang; WANG Wei-Hua

    2004-01-01

    @@ We report that bulk metallic glasses (BMGs) can be produced up to 2 mm by a copper mould casting in Cux Zr1-x binary alloy with a wide glass forming composition range (45 < x < 60 at.%). We find that the formation mechanism for the binary Cu-Zr binary BMG-forming alloy is obviously different from that of the intensively studied multicomponent BMGs. Our results demonstrate that the criteria for the multicomponent alloys with composition near deep eutectic and strong liquid behaviour are no longer the major concern for designing BMGs.

  11. Calculated Bulk Properties of the Actinide Metals

    DEFF Research Database (Denmark)

    Skriver, Hans Lomholt; Andersen, O. K.; Johansson, B.

    1978-01-01

    Self-consistent relativistic calculations of the electronic properties for seven actinides (Ac-Am) have been performed using the linear muffin-tin orbitals method within the atomic-sphere approximation. Exchange and correlation were included in the local spin-density scheme. The theory explains...... the variation of the atomic volume and the bulk modulus through the 5f series in terms of an increasing 5f binding up to plutonium followed by a sudden localisation (through complete spin polarisation) in americium...

  12. Diffusion and bulk flow in phloem loading

    DEFF Research Database (Denmark)

    Dölger, Julia; Rademaker, Hanna; Liesche, Johannes

    2014-01-01

    loading mechanism, active symplasmic loading, also called the polymer trap mechanism, where sucrose is transformed into heavier sugars, such as raffinose and stachyose, in the intermediary-type companion cells bordering the sieve elements in the minor veins of the phloem. Keeping the heavier sugars from......%-20% to the sucrose flux into the intermediary cells, while the main part is transported by diffusion. On the other hand, the subsequent sugar translocation into the sieve elements would very likely be carried predominantly by bulk water flow through the plasmodesmata. Thus, in contrast to apoplasmic loaders, all...

  13. Fabrication of Porous Bulk Metallic Glass

    Institute of Scientific and Technical Information of China (English)

    Keqiang QIU; Yinglei REN

    2005-01-01

    An open-cell porous bulk metallic glass (BMG)with a diameter of at least 6 mm was fabricated by using an U-turn quartz tube and infiltration casting aroundsoluble NaCl placeholders. The pore formation and glassy structure were examined by optical microscopy (OM), scanning electron microscopy (SEM) and X-ray diffraction (XRD). The results show that the pores or cells are connected to each other and the specimenis composed of a mostly glassy phase.This paper provides a suitable method for fabrication of porous BMG and BMG with larger size in diameter.

  14. Hubble Parameter in Bulk Viscous Cosmology

    CERN Document Server

    Tawfik, A; Wahba, M

    2009-01-01

    We discuss influences of bulk viscosity on the Early Universe, which is modeled by Friedmann-Robertson-Walker metric and Einstein field equations. We assume that the matter filling the isotropic and homogeneous background is relativistic viscous characterized by ultra-relativistic equations of state deduced from recent lattice QCD simulations. We obtain a set of complicated differential equations, for which we suggest approximate solutions for Hubble parameter $H$. We find that finite viscosity in Eckart and Israel-Stewart fluids would significantly modify our picture about the Early Universe.

  15. Production, Properties and Applications of Bulk Amorphous Alloys

    Institute of Scientific and Technical Information of China (English)

    Tao Zhang; Akihisa Inoue

    2000-01-01

    A review is given of recent work concerned with the production method, the characteristic properties(1) Bulk amorphous system; (2) Mechanical and magnetic properties of bulkamorphous alloys; (3)application of bulk amorphous alloys.

  16. Transport of Polycyclic Aromatic Hydrocarbons in Unsaturated Porous Media

    Science.gov (United States)

    Chahal, Maninder; Flury, Markus

    2016-04-01

    Polycyclic aromatic hydrocarbons (PAHs) are complex organic molecules containing 2 or more fused benzene rings. Being hydrophobic and non-polar, PAHs tend to partition to the organic matter in the soil from bulk aqueous phase. Though transport of these contaminants has been well studied in saturated environment, interactive mechanisms of these fluorescent compounds in unsaturated (identified by presence of air-water interface) porous media is still not well understood. We studied is the transport of fluoranthene in unsaturated porous media as facilitated by moving air-water interfaces. Confocal microscopy was used to visualize the interactions of fluoranthene particles in a glass channel packed with quartz glass beads. The packed glass channel was used to mimic a porous media and effects of an advancing and receding capillary fringe on the detachment of fluoranthene.

  17. Correlation of Neo-Sensitabs Tablet Diffusion Assay Results on Three Different Agar Media with CLSI Broth Microdilution M27-A2 and Disk Diffusion M44-A Results for Testing Susceptibilities of Candida spp. and Cryptococcus neoformans to Amphotericin B, Caspofungin, Fluconazole, Itraconazole, and Voriconazole▿

    Science.gov (United States)

    Espinel-Ingroff, A.; Canton, E.; Gibbs, D.; Wang, A.

    2007-01-01

    We compared the Neo-Sensitabs tablet assay to both reference M27-A2 broth microdilution and M44-A disk diffusion methods for testing susceptibilities of 110 isolates of Candida spp. and Cryptococcus neoformans to amphotericin B, caspofungin, fluconazole, itraconazole, and voriconazole. Neo-Sensitabs assay inhibition zone diameters in millimeters on three agars (Mueller-Hinton agar supplemented with 2% dextrose and 0.5 μg/ml methylene blue [MGM], Shadomy [SHA], and RPMI 1640 [RPMI, 2% dextrose]) were obtained at 24 to 72 h. The correlation coefficient of Neo-Sensitabs results with MICs was similar to that of the disk method for most of the five agents on MGM (R, 0.80 to 0.89 versus 0.76 to 0.89, respectively). Overall, superior correlation was observed at 24 h for most agents. The exception was amphotericin B (R values of 0.68 and 0.5 for disk and tablet, respectively, at 48 h versus 0.68 and 0.48, respectively, at 24 h). In general, Neo-Sensitabs results were less consistent on SHA and RPMI agars. Although agreement by breakpoint category of Neo-Sensitabs and disk results with CLSI method M27-A2 was also similar on MGM (92.7 to 98.2% versus 95.5 to 100%, respectively), the Neo-Sensitabs method failed to identify two of the six isolates with high amphotericin B MICs. These data suggest the potential value of the Neo-Sensitabs assay for testing at least four of the five agents against yeasts evaluated in the clinical laboratory. PMID:17215342

  18. Enhancing bulk superconductivity by engineering granular materials

    Science.gov (United States)

    Mayoh, James; García García, Antonio

    2014-03-01

    The quest for higher critical temperatures is one of the main driving forces in the field of superconductivity. Recent theoretical and experimental results indicate that quantum size effects in isolated nano-grains can boost superconductivity with respect to the bulk limit. Here we explore the optimal range of parameters that lead to an enhancement of the critical temperature in a large three dimensional array of these superconducting nano-grains by combining mean-field, semiclassical and percolation techniques. We identify a broad range of parameters for which the array critical temperature, TcArray, can be up to a few times greater than the non-granular bulk limit, Tc 0. This prediction, valid only for conventional superconductors, takes into account an experimentally realistic distribution of grain sizes in the array, charging effects, dissipation by quasiparticles and limitations related to the proliferation of thermal fluctuations for sufficiently small grains. For small resistances we find the transition is percolation driven. Whereas at larger resistances the transition occurs above the percolation threshold due to phase fluctuations. JM acknowledes support from an EPSRC Ph.D studentship, AMG acknowledges support from EPSRC, grant No. EP/I004637/1, FCT, grant PTDC/FIS/111348/2009 and a Marie Curie International Reintegration Grant PIRG07-GA-2010-268172.

  19. Characterization of bulk superconductors through EBSD methods

    Science.gov (United States)

    Koblischka, M. R.; Koblischka-Veneva, A.

    2003-10-01

    The application of electron backscatter diffraction (EBSD) technique to bulk high- Tc superconductors is presented and reviewed. Due to the ceramic nature and the complex crystallographic unit cells of the perovskite-type high- Tc superconductors, the EBSD analysis is not yet as common as it deserves. We have successfully performed EBSD analysis on a variety of high- Tc compounds and samples including polycrystalline YBCO (pure and doped by alkali metals), melt-textured YBCO, thin and thick films of YBCO; the “green phase” Y 2BaCuO 5, thin film and melt-textured NdBa 2Cu 3O x and Bi-2212 single crystals and tapes. It is shown that the surface preparation of the samples is crucial due to the small information depth (up to 100 nm) of the EBSD technique. High quality Kikuchi patterns are the requirement in order to enable the automated EBSD mapping, which yields phase distributions, individual grain orientations and the misorientation angle distribution. The results can be presented in form of mappings, as charts, and as pole figures. These informations are required for a better understanding of the growth mechanism(s) of bulk high- Tc superconductors intended for applications.

  20. Perovskite oxides: Oxygen electrocatalysis and bulk structure

    Science.gov (United States)

    Carbonio, R. E.; Fierro, C.; Tryk, D.; Scherson, D.; Yeager, Ernest

    1987-01-01

    Perovskite type oxides were considered for use as oxygen reduction and generation electrocatalysts in alkaline electrolytes. Perovskite stability and electrocatalytic activity are studied along with possible relationships of the latter with the bulk solid state properties. A series of compounds of the type LaFe(x)Ni1(-x)O3 was used as a model system to gain information on the possible relationships between surface catalytic activity and bulk structure. Hydrogen peroxide decomposition rate constants were measured for these compounds. Ex situ Mossbauer effect spectroscopy (MES), and magnetic susceptibility measurements were used to study the solid state properties. X ray photoelectron spectroscopy (XPS) was used to examine the surface. MES has indicated the presence of a paramagnetic to magnetically ordered phase transition for values of x between 0.4 and 0.5. A correlation was found between the values of the MES isomer shift and the catalytic activity for peroxide decomposition. Thus, the catalytic activity can be correlated to the d-electron density for the transition metal cations.

  1. A Batch Feeder for Inhomogeneous Bulk Materials

    Science.gov (United States)

    Vislov, I. S.; Kladiev, S. N.; Slobodyan, S. M.; Bogdan, A. M.

    2016-04-01

    The work includes the mechanical analysis of mechanical feeders and batchers that find application in various technological processes and industrial fields. Feeders are usually classified according to their design features into two groups: conveyor-type feeders and non-conveyor feeders. Batchers are used to batch solid bulk materials. Less frequently, they are used for liquids. In terms of a batching method, they are divided into volumetric and weighting batchers. Weighting batchers do not provide for sufficient batching accuracy. Automatic weighting batchers include a mass controlling sensor and systems for automatic material feed and automatic mass discharge control. In terms of operating principle, batchers are divided into gravitational batchers and batchers with forced feed of material using conveyors and pumps. Improved consumption of raw materials, decreased loss of materials, ease of use in automatic control systems of industrial facilities allows increasing the quality of technological processes and improve labor conditions. The batch feeder suggested by the authors is a volumetric batcher that has no comparable counterparts among conveyor-type feeders and allows solving the problem of targeted feeding of bulk material batches increasing reliability and hermeticity of the device.

  2. Bulk nanocrystalline Al prepared by cryomilling

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Bulk nanocrystalline Al was fabricated by mechanically milling at cryogenic temperature (cryomilling) and then by hot pressing in vacuum. By using X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM), the microstructure evolution of the material during cryomilling and consolidation was investigated. With increasing the milling time, the grain size decreased sharply and reduced to 42 nm when cryomilled for 12 h. The grains had grown up, and the columnar grain was formed under the hot pressing and extrusion compared with the cryomilled powders. The grain size of as-extruded specimen was approximately 300-500 nm. The reason of high thermal stability of this bulk was attributed primarily to the Zener pinning from the grain boundary of the AlN arising from cryomilling and the solute drag of the impurity. Tensile tests show that the strength of nanocrystalline Al is enhanced with decreasing grain size. The ultimate tensile strength and tensile elongation were 173 MPa and 17.5%, respectively. It appears that the measured high strength in the cryomilled Al is related to a grain-size effect, dispersion strengthening, and dislocation strengthening.

  3. Substantial bulk photovoltaic effect enhancement via nanolayering.

    Science.gov (United States)

    Wang, Fenggong; Young, Steve M; Zheng, Fan; Grinberg, Ilya; Rappe, Andrew M

    2016-01-21

    Spontaneous polarization and inversion symmetry breaking in ferroelectric materials lead to their use as photovoltaic devices. However, further advancement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing photocurrent. By unravelling the correlation between ferroelectric materials' responses to solar irradiation and their local structure and electric polarization landscapes, here we show from first principles that substantial bulk photovoltaic effect enhancement can be achieved by nanolayering PbTiO3 with nickel ions and oxygen vacancies ((PbNiO2)x(PbTiO3)(1-x)). The enhancement of the total photocurrent for different spacings between the Ni-containing layers can be as high as 43 times due to a smaller bandgap and photocurrent direction alignment for all absorption energies. This is due to the electrostatic effect that arises from nanolayering. This opens up the possibility for control of the bulk photovoltaic effect in ferroelectric materials by nanoscale engineering of their structure and composition.

  4. Degree of Conversion and BisGMA, TEGDMA, UDMA Elution from Flowable Bulk Fill Composites.

    Science.gov (United States)

    Lempel, Edina; Czibulya, Zsuzsanna; Kovács, Bálint; Szalma, József; Tóth, Ákos; Kunsági-Máté, Sándor; Varga, Zoltán; Böddi, Katalin

    2016-05-20

    The degree of conversion (DC) and the released bisphenol A diglycidyl ether dimethacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) monomers of bulk-fill composites compared to that of conventional flowable ones were assessed using micro-Raman spectroscopy and high performance liquid chromatography (HPLC). Four millimeter-thick samples were prepared from SureFil SDR Flow (SDR), X-tra Base (XB), Filtek Bulk Fill (FBF) and two and four millimeter samples from Filtek Ultimate Flow (FUF). They were measured with micro-Raman spectroscopy to determine the DC% of the top and the bottom surfaces. The amount of released monomers in 75% ethanol extraction media was measured with HPLC. The differences between the top and bottom DC% were significant for each material. The mean DC values were in the following order for the bottom surfaces: SDR_4mm_20s > FUF_2mm_20s > XB_4mm_20s > FBF_4mm_20s > XB_4mm_10s > FBF_4mm_10s > FUF_4mm_20s. The highest rate in the amount of released BisGMA and TEGDMA was found from the 4 mm-thick conventional flowable FUF. Among bulk-fills, FBF showed a twenty times higher amount of eluted UDMA and twice more BisGMA; meanwhile, SDR released a significantly higher amount of TEGDMA. SDR bulk-fill showed significantly higher DC%; meanwhile XB, FBF did not reach the same level DC, as that of the 2 mm-thick conventional composite at the bottom surface. Conventional flowable composites showed a higher rate of monomer elution compared to the bulk-fills, except FBF, which showed a high amount of UDMA release.

  5. Degree of Conversion and BisGMA, TEGDMA, UDMA Elution from Flowable Bulk Fill Composites

    Science.gov (United States)

    Lempel, Edina; Czibulya, Zsuzsanna; Kovács, Bálint; Szalma, József; Tóth, Ákos; Kunsági-Máté, Sándor; Varga, Zoltán; Böddi, Katalin

    2016-01-01

    The degree of conversion (DC) and the released bisphenol A diglycidyl ether dimethacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) monomers of bulk-fill composites compared to that of conventional flowable ones were assessed using micro-Raman spectroscopy and high performance liquid chromatography (HPLC). Four millimeter-thick samples were prepared from SureFil SDR Flow (SDR), X-tra Base (XB), Filtek Bulk Fill (FBF) and two and four millimeter samples from Filtek Ultimate Flow (FUF). They were measured with micro-Raman spectroscopy to determine the DC% of the top and the bottom surfaces. The amount of released monomers in 75% ethanol extraction media was measured with HPLC. The differences between the top and bottom DC% were significant for each material. The mean DC values were in the following order for the bottom surfaces: SDR_4mm_20s > FUF_2mm_20s > XB_4mm_20s > FBF_4mm_20s > XB_4mm_10s > FBF_4mm_10s > FUF_4mm_20s. The highest rate in the amount of released BisGMA and TEGDMA was found from the 4 mm-thick conventional flowable FUF. Among bulk-fills, FBF showed a twenty times higher amount of eluted UDMA and twice more BisGMA; meanwhile, SDR released a significantly higher amount of TEGDMA. SDR bulk-fill showed significantly higher DC%; meanwhile XB, FBF did not reach the same level DC, as that of the 2 mm-thick conventional composite at the bottom surface. Conventional flowable composites showed a higher rate of monomer elution compared to the bulk-fills, except FBF, which showed a high amount of UDMA release. PMID:27213361

  6. Degree of Conversion and BisGMA, TEGDMA, UDMA Elution from Flowable Bulk Fill Composites

    Directory of Open Access Journals (Sweden)

    Edina Lempel

    2016-05-01

    Full Text Available The degree of conversion (DC and the released bisphenol A diglycidyl ether dimethacrylate (BisGMA, triethylene glycol dimethacrylate (TEGDMA and urethane dimethacrylate (UDMA monomers of bulk-fill composites compared to that of conventional flowable ones were assessed using micro-Raman spectroscopy and high performance liquid chromatography (HPLC. Four millimeter-thick samples were prepared from SureFil SDR Flow (SDR, X-tra Base (XB, Filtek Bulk Fill (FBF and two and four millimeter samples from Filtek Ultimate Flow (FUF. They were measured with micro-Raman spectroscopy to determine the DC% of the top and the bottom surfaces. The amount of released monomers in 75% ethanol extraction media was measured with HPLC. The differences between the top and bottom DC% were significant for each material. The mean DC values were in the following order for the bottom surfaces: SDR_4mm_20s > FUF_2mm_20s > XB_4mm_20s > FBF_4mm_20s > XB_4mm_10s > FBF_4mm_10s > FUF_4mm_20s. The highest rate in the amount of released BisGMA and TEGDMA was found from the 4 mm-thick conventional flowable FUF. Among bulk-fills, FBF showed a twenty times higher amount of eluted UDMA and twice more BisGMA; meanwhile, SDR released a significantly higher amount of TEGDMA. SDR bulk-fill showed significantly higher DC%; meanwhile XB, FBF did not reach the same level DC, as that of the 2 mm-thick conventional composite at the bottom surface. Conventional flowable composites showed a higher rate of monomer elution compared to the bulk-fills, except FBF, which showed a high amount of UDMA release.

  7. 19 CFR 151.24 - Unlading facilities for bulk sugar.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Unlading facilities for bulk sugar. 151.24 Section... OF THE TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Sugars, Sirups, and Molasses § 151.24 Unlading facilities for bulk sugar. When dutiable sugar is to be imported in bulk, a...

  8. 30 CFR 56.6802 - Bulk delivery vehicles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bulk delivery vehicles. 56.6802 Section 56.6802... § 56.6802 Bulk delivery vehicles. No welding or cutting shall be performed on a bulk delivery vehicle until the vehicle has been washed down and all explosive material has been removed. Before welding...

  9. 30 CFR 57.6802 - Bulk delivery vehicles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bulk delivery vehicles. 57.6802 Section 57.6802...-Surface and Underground § 57.6802 Bulk delivery vehicles. No welding or cutting shall be performed on a bulk delivery vehicle until the vehicle has been washed down and all explosive material has...

  10. MICROBIOLOGICAL ASSAY FOR VITAMIN B

    OpenAIRE

    Bishnoi Kapil*, , ,; Kataria Mahesh; Singhal Vipin; Gupta Deepika

    2012-01-01

    Micronutrients added to foods are analyzed using various procedures depending on their nature and properties. The microbiological assays are better than chemical method because any suitable change in vitamin molecule which may not be detected by chemical method will be revealed by change in microbial activity. The microbiological assay of vitamins is based upon the comparison of the stimulation of growth of bacteria by measured concentration of vitamin with that produced by known concentratio...

  11. Contemplative Media Studies

    Directory of Open Access Journals (Sweden)

    Kevin Healey

    2015-08-01

    Full Text Available The psychological and socio-economic implications of digital technologies call for scholarship that engages questions about the nature of human consciousness, the construction of the self and the ethics of technical development. In this article, I outline a framework for an approach called contemplative media studies. This approach incorporates several different scholarly threads, namely: via critical political-economic media scholarship, a focus on achieving social and economic justice through policy initiatives and structural reform; via media and religious scholarship, an interest in the religious dimensions of digital culture and the role of media in shaping religious identity; and via contemplative studies, an appreciation of the applicability of contemplative principles to research methods and theory. This framework allows us to examine the spiritual ideology that drives the construction of commercial digital platforms and to ask whether alternative platforms might better catalyze human development. Anchored in a critical commitment to socio-economic justice, contemplative media studies is aimed at articulating an ethically-responsive and economically-sustainable architecture of human flourishing.

  12. Doing social media analytics

    Directory of Open Access Journals (Sweden)

    Phillip Brooker

    2016-07-01

    Full Text Available In the few years since the advent of ‘Big Data’ research, social media analytics has begun to accumulate studies drawing on social media as a resource and tool for research work. Yet, there has been relatively little attention paid to the development of methodologies for handling this kind of data. The few works that exist in this area often reflect upon the implications of ‘grand’ social science methodological concepts for new social media research (i.e. they focus on general issues such as sampling, data validity, ethics, etc.. By contrast, we advance an abductively oriented methodological suite designed to explore the construction of phenomena played out through social media. To do this, we use a software tool – Chorus – to illustrate a visual analytic approach to data. Informed by visual analytic principles, we posit a two-by-two methodological model of social media analytics, combining two data collection strategies with two analytic modes. We go on to demonstrate each of these four approaches ‘in action’, to help clarify how and why they might be used to address various research questions.

  13. Natural thermal convection in fractured porous media

    Science.gov (United States)

    Adler, P. M.; Mezon, C.; Mourzenko, V.; Thovert, J. F.; Antoine, R.; Finizola, A.

    2015-12-01

    In the crust, fractures/faults can provide preferential pathways for fluid flow or act as barriers preventing the flow across these structures. In hydrothermal systems (usually found in fractured rock masses), these discontinuities may play a critical role at various scales, controlling fluid flows and heat transfer. The thermal convection is numerically computed in 3D fluid satured fractured porous media. Fractures are inserted as discrete objects, randomly distributed over a damaged volume, which is a fraction of the total volume. The fluid is assumed to satisfy Darcy's law in the fractures and in the porous medium with exchanges between them. All simulations were made for Rayleigh numbers (Ra) equilibrium with the medium), cubic boxes and closed-top conditions. Checks were performed on an unfractured porous medium and the convection cells do start for the theoretical value of Ra, namely 4p². 2D convection was verified up to Ra=800. The influence of parameters such as fracture aperture (or fracture transmissivity), fracture density and fracture length is studied. Moreover, these models are compared to porous media with the same macroscopic permeability. Preliminary results show that the non-uniqueness associated with initial conditions which makes possible either 2D or 3D convection in porous media (Schubert & Straus 1979) is no longer true for fractured porous media (at least for 50bulk permeability.

  14. Prevalence of human papillomavirus in 5,072 consecutive cervical SurePath samples evaluated with the Roche cobas HPV real-time PCR assay.

    Directory of Open Access Journals (Sweden)

    Sarah Preisler

    Full Text Available New commercially available Human Papillomavirus (HPV assays need to be evaluated in a variety of cervical screening settings. Cobas HPV Test (cobas is a real-time PCR-based assay allowing for separate detection of HPV genotypes 16 and 18 and a bulk of 12 other high-risk genotypes. The aim of the present study, Horizon, was to assess the prevalence of high-risk HPV infections in an area with a high background risk of cervical cancer, where women aged 23-65 years are targeted for cervical screening. We collected 6,258 consecutive cervical samples from the largest cervical screening laboratory in Denmark serving the whole of Copenhagen. All samples were stored in SurePath media. In total, 5,072 samples were tested with cobas, Hybrid Capture 2 High Risk HPV DNA test (HC2 and liquid-based cytology. Of these, 27% tested positive on cobas. This proportion decreased by age, being 43% in women aged 23-29 years and 10% in women aged 60-65 years. HC2 assay was positive in 20% of samples, and cytology was abnormal (≥ atypical squamous cells of undetermined significance for 7% samples. When only samples without recent abnormalities were taken into account, 24% tested positive on cobas, 19% on HC2, and 5% had abnormal cytology. The proportion of positive cobas samples was higher than in the ATHENA trial. The age-standardized cobas positivity vs. cytology abnormality was 3.9 in our study and 1.7 in ATHENA. If in Copenhagen the presently used cytology would be replaced by cobas in women above age 30 years, an extra 11% of women would based on historical data be expected to have a positive cobas test without an underlying cervical intraepithelial lesion grade 3 or worse. Countries with a high prevalence of HPV infections should therefore proceed to primary HPV-based cervical screening with caution.

  15. Media for Reflection

    DEFF Research Database (Denmark)

    Knudsen, Morten

    2016-01-01

    This article develops the concept media for reflection in the interest of conceptualizing the interpretative frames that enable and limit reflection in management and leadership education. The concept ‘media for reflection’ allows us to conceptualize the social and cultural mediation of reflection...... without reducing reflection to an effect of the social structures and cultural norms in which it is embedded. Based on the developed theoretical framework, this article analyses how a renaissance ‘mirror for princes’ and contemporary research-based management education mediate reflection. The content...... of the mediations is analysed as well as the societal and organizational background. Furthermore, the means by which the two media enable and limit reflection in different ways is compared. Finally, the article discusses possible implications of the analysis in terms of management and leadership education....

  16. Media and metamedia management

    CERN Document Server

    Araújo, Xosé; Fernández, Valentín; García, Xosé

    2017-01-01

    Media and Metamedia Management has contributions from seven prestigious experts, who offer their expertise and the view from their vantage point on communication, journalism, advertising, audiovisual, and corporate, political, and digital communication, paying special attention to the role of new technologies, the Internet and social networks, also from an ethics and legal dimension. A total of 118 authors belonging to 31 universities from Spain, Portugal, England and Ecuador have contributed to this book edited, coordinated and introduced by professors Francisco Campos-Freire and Xosé López-García, from the University of Santiago de Compostela, José Rúas-Araújo, from the University of Vigo, and Valentín A. Martínez-Fernández, from the University of A Coruña. Readers may also enjoy 66 articles, grouped into diverse chapters, on Journalism and cyberjournalism, audiovisual sector and media economy, corporate and institutional communication, and new media and metamedia.

  17. Open Media Training Session

    CERN Document Server

    CERN. Geneva; Marchant, Nadia

    2010-01-01

    Have you ever wondered how the media work and why some topics make it into the news and other don't? Would you like to know how to (and how not to) give an interview to a journalist? With the LHC preparing for first collisions at high energies, the world's media are again turning their attention to CERN. We're all likely to be called upon to explain what is happening at CERN to media, friends and neighbours. The seminar will be given by BBC television news journalists Liz Pike and Nadia Marchant, and will deal with the kind of questions we're likely to be confronted with through the restart period. Follow the webcast: http://webcast.cern.ch/

  18. Media and Multiplicity

    DEFF Research Database (Denmark)

    Blaagaard, Bolette

    2010-01-01

    such as the Danish cartoon controversy, and Dutch politician Geert Wilders’s film, Fitna. Simultaneously, however, the media is more diverse and rhizomatic than ever and offers potential for cosmopolitanism, transnational ethical relations as well as radical anti-racist and anti-fascist interventions. This article......In the past few years continental Europe has experienced a resurgence of right-wing party politics, nationalism and xenophobia. In this nationalist revival the media and advanced communications technologies have played a significant role, as evidenced by the debates following cases...... explores the tensions within the relation between journalistic practice and the construction of the idea of the nation and the multiplicity of media and cultures which inhabit the spheres of journalism and nation....

  19. SELF-MEDIA

    DEFF Research Database (Denmark)

    Fausing, Bent

    2014-01-01

    The self and identity are not only issues connected to the selfies. They are connected to the development of media since the renaissance; this is the thesis of the following key-note. The subject, the self, is most clearly exposed in the face, and face and identity becomes important in the media...... since the renaissance. The selfies is just the newest development is this tradition, which began with the invention of the mirror, the book (printing), and the miniature painting. They all put the subject as both maker and receiver in the center. This was the birth of the modern subject. The development...... continued throughout the coming centuries. The selfies is the latest invention to discover, explore, visualize and find the self of the subject. The following will therefore naturally focus on the self, the face where the self is most clearly expressed and seen, and the self-media, where the subject can...

  20. Media and Sexuality

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Carvalho

    2010-03-01

    Full Text Available One of the distinctive marks of current capitalism is the presence of mass media constituting the psyche in different aspects. Today, we observe the multiplication of many contents with erotic appeal in the media and the effects of this process are still to be known, particularly in the matter of sexuality. Concretely, what we have is that the practices and the effective conceptions of sexuality are suffering an accelerated transformation that involves the abandonment of the traditional practices. In this context, we can ask about the sense that is attributed to sexuality experiences and evaluate the impact of the different "manners of being" which are referred to sexuality and systematically diffused by the media. Therefore, we can explore the implications of this new scenery for different social realities: the family institution, the affectionate and loving relationships, the school and professional everyday life, as well as the formulation of public politics in this field.

  1. Corporeal-Locomotive Media

    DEFF Research Database (Denmark)

    Nørgård, Rikke Toft

    activities and experiences across the abovementioned gameworlds. As a consequence, the article points towards the centrality of expressive first-person corporeality and locomotion in digital games – a circumstance that sets the practice and experience of digital games apart from media practices...... and experiences such as reading or listening to a story and watching a movie or theatre play and other traditional or new media forms. These circumstances make the article question whether digital games can be understood as (new) media form at all and, thus, it points towards a possible new vocabulary...... and structure’ of a couple of specific interactions, expressions and experiences that in the study have proven to be characteristic of being a gameplayer in gameplay in digital games – regardless of whether you are a child playing Temple Run 2 or Frut Ninja on the iPhone, a tween playing Battlefield 3 on your...

  2. Internet and Cross Media Productions

    DEFF Research Database (Denmark)

    Petersen, Anja Bechmann

    2006-01-01

    . The aim of this article is to examine the roles of the Internet when emphasis is put on cross media rather than convergence. This article proposes not one unidirectional convergent tendency but manifold roles of the Internet in cross media communication. Inside the media organizations, however......, the Internet continues to play a minor role when compared to older media. The content of the cross media concepts and organizations' history are crucial elements in deciding the priority and use of platforms. Methodologically, the article approaches cross media and the roles of the Internet on a micro......Convergence is one of the hot topics in Internet studies. Recently, however, media organizations have turned their focus to cross media communication. Media organizations are interested in optimizing communication across platforms such as TV, radio, websites, mobile telephones and newspapers...

  3. Correlation between the genotoxicity endpoints measured by two different genotoxicity assays: comet assay and CBMN assay

    Directory of Open Access Journals (Sweden)

    Carina Ladeira

    2015-06-01

    The results concerning of positive findings by micronuclei and non significant ones by comet assay, are corroborated by Deng et al. (2005 study performed in workers occupationally exposed to methotrexate, also a cytostatic drug. According to Cavallo et al. (2009, the comet assay seems to be more suitable for the prompt evaluation of the genotoxic effects, for instance, of polycyclic aromatic hydrocarbons mixtures containing volatile substances, whereas the micronucleus test seems more appropriate to evaluate the effects of exposure to antineoplastic agents. However, there are studies that observed an increase in both the comet assay and the micronucleus test in nurses handling antineoplastic drugs, although statistical significance was only seen in the comet assay, quite the opposite of our results (Maluf & Erdtmann, 2000; Laffon et al. 2005.

  4. Death in media

    Directory of Open Access Journals (Sweden)

    Pavićević Aleksandra

    2010-01-01

    Full Text Available This paper discusses the role of media in a construction of public image speech and presentation of death. The main research questions could be posed as follows: does the media discourse confirm a thesis about modern society as the one which intensely avoids encounter with Death, or does it defy it? Frequent images or hints of death in visual media in films informative and entertainment programs-suggest certain changes related to this issue in the past few decades. This analysis focuses on printed media hence the paper assesses numerous issues of the daily journal Politika from 1963, 1972, 1973, 1979, 1985, 1991, 1995, 1999, 2007 and 2008, as well as some other daily journals after 2000. The analysis confirms a strong connection between the current political systems and ideology and speech about death. In addition, it reveals a political usage of this event but also speaks up about cultural and historical models, underlying all other constructions. During the 1960's and 1970's, the presentations, including the speech about death relied on the traditional understandings about inevitability of death and dying, and alternatively on atheistic beliefs related to the progress and wellbeing of the society. In this particular discourse, death was present to a limited degree, serving primarily to glorify socialist order. The end of the 1970's witnessed an increase in the glorification of the death, correlated with the decrease of the dominant political ideology. On the other hand, the 1990's brought about more presence of the national and religious symbolism and glorification of the dead as heroes. After 2000, mercantilism is evident throughout the media. All of the media broadcast drastic images of death and dead, thus providing an answer to the posed question at the beginning of this paper about the relationship of the modern society towards death but nevertheless, this still leaves out many implicit consequences and possible meanings.

  5. Acute otitis media.

    Science.gov (United States)

    Dickson, Gretchen

    2014-03-01

    One in 4 children will have at least 1 episode of acute otitis media (AOM) by age 10 years. AOM results from infection of fluid that has become trapped in the middle ear. The bacteria that most often cause AOM are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Differentiating AOM from otitis media with effusion (OME) is a critical skill for physicians, as accurate diagnosis will guide appropriate treatment of these conditions. Although fluid is present in the middle ear in both conditions, the fluid is not infected in OME as is seen in AOM patients.

  6. Mobile Media Photography

    DEFF Research Database (Denmark)

    Svabo, Connie; Shanks, Michael

    2013-01-01

    Mobile media photography marks a shift in orientation from the image towards photography as a mode of engagement. This leads is to explore the processes of experience and documentation that mobile media help to constitute. We unfold two aspects of the process of photography: photography as temporal......, archaeological engagement, and photography as spatial, geographical engagement. Finally, as a closing perspective we point out that vernacular photography may be read as an intersection between a personal means of expression and corporate financial interest....

  7. Biorelevant dissolution media

    DEFF Research Database (Denmark)

    Ilardia-Arana, David; Kristensen, Henning G; Müllertz, Anette

    2006-01-01

    Biorelevant dissolution media containing bile salt and lecithin at concentrations appropriate for fed and fasted state are useful when testing oral solid formulations of poorly water-soluble drugs. Dilution of amphiphile solutions affects the aggregation state of the amphiphiles because bile salt....... Dilution of the two- and four component media caused enlargement of the mixed micelles and formation of vesicles. The solubility of estradiol in the buffer solution was increased with addition of the amphiphiles. A good correlation (R(2) = 0.987) was found between estradiol solubility and mass...

  8. HTML5 Media

    CERN Document Server

    Powers, Shelley

    2011-01-01

    If you're a web developer or designer familiar with CSS and JavaScript, this tightly focused introduction shows you how to add HTML5 media elements to your web pages, and how to provide custom controls for letting web visitors interact with the content. You'll also learn how to provide subtitles and captions, using file formats that work in browsers now. This book includes code samples and downloadable examples to help you take full advantage of audio and video in your web pages. Ensure your audio or video works in all browsers that support HTML5 media elementsLearn about widely supported me

  9. Hypertextuality and Social Media

    DEFF Research Database (Denmark)

    Albu, Oana Brindusa; Etter, Michael

    2016-01-01

    Texts and conversations are central to the constitution of organizations. Through the use of social media technologies, organizational members and nonorganizational members alike have the capacity to author organizational texts that co-constitute an organization as an entity with a specific...... identity in a situational space and time. The implications of this ability are underexplored. This study focused on how two organizations used the social media technology Twitter to interact with their constituents. The article adopts communication-centered and sociomateriality perspectives to illustrate...

  10. Multisided Media Markets

    DEFF Research Database (Denmark)

    Lindstädt, Nadine

    Media markets recently have been identified as multisided markets. The application of the theory of multisided markets provides a better understanding of such markets. It enriched the hitherto economic approach and led to new insights and perspectives especially for the antitrust authorities when...... evaluating competition constraints and mergers. This paper reviews the theory of multisided markets and subsequently applies it to media markets. Finally the paper draws attention to the new perspectives and insights the theory provides but also brings open research questions to light....

  11. Smartphones as locative media

    CERN Document Server

    Frith, Jordan

    2015-01-01

    Smartphone adoption has surpassed 50% of the population in more than 15 countries, and there are now more than one million mobile applications people can download to their phones. Many of these applications take advantage of smartphones as locative media, which is what allows smartphones to be located in physical space. Applications that take advantage of people's location are called location-based services, and they are the focus of this book. Smartphones as locative media raise important questions about how we understand the complicated relationship between the Internet and physical space

  12. Social Media and Marketing

    OpenAIRE

    Jaffrey, Jarrar

    2011-01-01

    During different time era’s different methods of communications has developed and changed the everyday life. Social media has become the way of communication in the 21st-century, enabling us to express our thoughts, ideas and feelings in a complete new way. This way of communication have also had a huge impact on corporations, where they have realized that without a proper plan and social media strategy they have no chance to stand out in the rapidly changing digital space. To ensure a succes...

  13. Technical issues of a high-Tc superconducting bulk magnet

    Science.gov (United States)

    Fujimoto, Hiroyuki

    2000-06-01

    Superconducting magnets made of high-Tc superconductors are promising for industrial applications. It is well known that REBa2Cu3O7-x superconductors prepared by melt processes have a high critical current density, Jc, at 77 K and high magnetic fields. The materials are very promising for high magnetic field applications as a superconducting permanent/bulk magnet with liquid-nitrogen refrigeration. Light rare-earth (LRE) BaCuO bulks, compared with REBaCuO bulks, exhibit a larger Jc in high magnetic fields and a much improved irreversibility field, Hirr, at 77 K. In this study, we discuss technical issues of a high-Tc superconducting bulk magnet, namely the aspects of the melt processing for bulk superconductors, their characteristic superconducting properties and mechanical properties, and trapped field properties of a superconducting bulk magnet. One of the possible applications is a superconducting bulk magnet for the magnetically levitated (Maglev) train in the future.

  14. TAXATION OF SOCIAL MEDIA ADVERTISEMENTS

    Directory of Open Access Journals (Sweden)

    F. Rifat ORTAÇ

    2016-01-01

    Full Text Available Today, the use of Internet and in particular social media as advertising tools brings the question of how the advertisement in social media should be taxed. This is not only seen as a problem in our country, but in the international platform as well. In the first part of the study, the definition of social media is given; in the second part, Social Media Brand Communities and Fun Pages are discussed; in the third part, a comparison of Social Media Con- tents and Public Goods, Global Public Goods and Club Goods is made; in the fourth part that Conclusion and Suggestions how social media is taxed is discussed.

  15. Media Philosophy— A Reasonable Programme?

    OpenAIRE

    Schmidt, Siegfried J

    2008-01-01

    It is beyond any doubt that media have an enormous impact on our media-culture societies. Media in?uence our perception and our knowledge, our memory as well as our emotions. They create public spheres and public opinions and give rise to media realities. Media shape our socialisation and our communality. They transform economy, politics, science, religion and law. “What we know about our society, even about our world we are living in, we know via the mass media.” (Luhmann 1996:9; my translat...

  16. Bulk disk resonator based ultrasensitive mass sensor

    DEFF Research Database (Denmark)

    Cagliani, Alberto; Davis, Zachary James

    2009-01-01

    In the framework of developing an innovative label-free sensor for multiarrayed biodetection applications, we present a novel bulk resonator based mass sensor. The sensor is a polysilicon disk which shows a Q-factor of 6400 in air at 68.8 MHz, resulting in mass resolutions down in the femtogram...... range. The sensor has been characterized in terms of sensitivity both for distributed mass detection, performing six consecutive depositions of e-beam evaporated Au, and localized mass detection, depositing approximately 7.5 pg of Pt/Ga/C three times consecutively with a Focused Ion Beam system....... The sensor has an extremely high distributed mass to frequency shift sensitivity of 60104 Hzcm2/¿g and shows a localized mass to frequency sensitivity up to 4405 Hz/pg with a localized mass resolution down to 15 fg. The device has been fabricated with a new microfabrication process that uses only two...

  17. Bulk heterojunction solar cells of three polythienothiophenes

    Directory of Open Access Journals (Sweden)

    Elif Alturk Parlak

    2015-06-01

    Full Text Available Semiconducting conjugated copolymers poly(3-phenyl-2-(thiophen-2-ylthieno[3,2-b]thiophene (PTTPh, poly(3-(4-methoxyphenyl-2-(thiophen-2-ylthieno[3,2-b]thiophene (PTTPh-OMe and poly(3-(4-N,N-dimethylaminophenyl-2-(thiophen-2-ylthieno[3,2-b]thiophene (PTTPh-N(CH 3 2, which were synthesized previously through Suzuki coupling method, were fabricated for solar cell applications. The devices had a structure of glass/ITO/PEDOT:PSS/polymer:PC61BM/Al. Bulk heterojunction photovoltaic cells were prepared as blends of PTTPh, PTTPh-OMe, PTTPh-N(CH 3 2 and PC61BM in a 1:1 ratio, which delivered power conversion efficiencies of 0.43%, 0.039% and 0.027%, respectively, without addition of additives or device optimization.

  18. Universe Models with Negative Bulk Viscosity

    CERN Document Server

    Brevik, Iver

    2013-01-01

    The concept of negative temperatures has occasionally been used in connection with quantum systems. A recent example of this sort is reported in the paper of S. Braun et al. [Science 339,52 (2013)], where an attractively interacting ensemble of ultracold atoms is investigated experimentally and found to correspond to a negative-temperature system since the entropy decreases with increasing energy at the high end of the energy spectrum. As the authors suggest, it would be of interest to investigate whether a suitable generalization of standard cosmological theory could be helpful, in order to elucidate the observed accelerated expansion of the universe usually explained in terms of a positive tensile stress (negative pressure). In the present note we take up this basic idea and investigate a generalization of the standard viscous cosmological theory, not by admitting negative temperatures but instead by letting the bulk viscosity take negative values. Evidently, such an approach breaks standard thermodynamics,...

  19. DEPLOYMENT OF THE BULK TRITIUM SHIPPING PACKAGE

    Energy Technology Data Exchange (ETDEWEB)

    Blanton, P.

    2013-10-10

    A new Bulk Tritium Shipping Package (BTSP) was designed by the Savannah River National Laboratory to be a replacement for a package that has been used to ship tritium in a variety of content configurations and forms since the early 1970s. The BTSP was certified by the National Nuclear Safety Administration in 2011 for shipments of up to 150 grams of Tritium. Thirty packages were procured and are being delivered to various DOE sites for operational use. This paper summarizes the design features of the BTSP, as well as associated engineered material improvements. Fabrication challenges encountered during production are discussed as well as fielding requirements. Current approved tritium content forms (gas and tritium hydrides), are reviewed, as well as, a new content, tritium contaminated water on molecular sieves. Issues associated with gas generation will also be discussed.

  20. Bulk metamaterials: Design, fabrication and characterization

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Alabastri, Alessandro

    2009-01-01

    Bulk metamaterials claim a lot of attention worldwide. We report about our activity and advances in design, fabrication and characterization of metal-dielectric composites with three-dimensional lattices. The nomenclature of designs exhibiting negative index behaviour in the near infrared includes...... the generic family of so-called nested structures. Such designs allow keeping the cubic symmetry of the unit cell along with the electric and magnetic responses showed by different parts in separate. For extraction of effective parameters we employ homemade wave propagation retrieving method free from...... ambiguity generic to the standard S-parameters retrieval method. Accurateness of the method is highlighted by a set of numerical checks. To fabricate smooth metal three-dimensional structures we develop an electroless chemical technique. We present the results of silver deposition on the surface of a 30...

  1. On bulk viscosity and moduli decay

    CERN Document Server

    Laine, M

    2010-01-01

    This pedagogically intended lecture, one of four under the header "Basics of thermal QCD", reviews an interesting relationship, originally pointed out by Bodeker, that exists between the bulk viscosity of Yang-Mills theory (of possible relevance to the hydrodynamics of heavy ion collision experiments) and the decay rate of scalar fields coupled very weakly to a heat bath (appearing in some particle physics inspired cosmological scenarios). This topic serves, futhermore, as a platform on which a number of generic thermal field theory concepts are illustrated. The other three lectures (on the QCD equation of state and the rates of elastic as well as inelastic processes experienced by heavy quarks) are recapitulated in brief encyclopedic form.

  2. Transformation of bulk alloys to oxide nanowires

    Science.gov (United States)

    Lei, Danni; Benson, Jim; Magasinski, Alexandre; Berdichevsky, Gene; Yushin, Gleb

    2017-01-01

    One dimensional (1D) nanostructures offer prospects for enhancing the electrical, thermal, and mechanical properties of a broad range of functional materials and composites, but their synthesis methods are typically elaborate and expensive. We demonstrate a direct transformation of bulk materials into nanowires under ambient conditions without the use of catalysts or any external stimuli. The nanowires form via minimization of strain energy at the boundary of a chemical reaction front. We show the transformation of multimicrometer-sized particles of aluminum or magnesium alloys into alkoxide nanowires of tunable dimensions, which are converted into oxide nanowires upon heating in air. Fabricated separators based on aluminum oxide nanowires enhanced the safety and rate capabilities of lithium-ion batteries. The reported approach allows ultralow-cost scalable synthesis of 1D materials and membranes.

  3. Organoboron polymers for photovoltaic bulk heterojunctions.

    Science.gov (United States)

    Cataldo, Sebastiano; Fabiano, Simone; Ferrante, Francesco; Previti, Francesco; Patanè, Salvatore; Pignataro, Bruno

    2010-07-15

    We report on the application of three-coordinate organoboron polymers, inherently strong electron acceptors, in flexible photovoltaic (PV) cells. Poly[(1,4-divinylenephenylene)(2,4,6-triisopropylphenylborane)] (PDB) has been blended with poly(3-hexylthiophene-2,5-diyl) (P3HT) to form a thin film bulk heterojunction (BHJ) on PET/ITO substrates. Morphology may be modulated to give a high percentage of domains (10-20 nm in size) allowing exciton separation. The photoelectric properties of the BHJs in devices with aluminium back electrodes were imaged by light beam induced current (LBIC) and light beam induced voltage (LBIV) techniques. Open circuit voltages, short circuit currents and overall external quantum efficiencies obtained are among the highest reported for all-polymer PV cells.

  4. New optical technique for bulk magnetostriction measurement

    CERN Document Server

    Samata, H; Uchida, T; Abe, S

    2000-01-01

    A new optical technique was applied to the measurement of magnetostriction in bulk samples. This technique utilizes an optical fiber bundle, AC-modulated light and lock-in detection. Deformation of the sample is determined from the ratio of the incident and reflected light intensities. Noise due to the instability of the light source is eliminated by obtaining the ratio of the incident and reflected light intensities, and the noise caused in the detector circuit can be reduced by lock-in detection. The performance of this method was characterized with a series of measurements using a gold film and crystal disks of pure iron and nickel. This technique offers a resolution of 0.5 nm and is sensitive enough to measure magnetostriction as small as 5x10 sup - sup 7 in 1 mm thick samples.

  5. Bulk semiconducting scintillator device for radiation detection

    Energy Technology Data Exchange (ETDEWEB)

    Stowe, Ashley C.; Burger, Arnold; Groza, Michael

    2016-08-30

    A bulk semiconducting scintillator device, including: a Li-containing semiconductor compound of general composition Li-III-VI.sub.2, wherein III is a Group III element and VI is a Group VI element; wherein the Li-containing semiconductor compound is used in one or more of a first mode and a second mode, wherein: in the first mode, the Li-containing semiconductor compound is coupled to an electrical circuit under bias operable for measuring electron-hole pairs in the Li-containing semiconductor compound in the presence of neutrons and the Li-containing semiconductor compound is also coupled to current detection electronics operable for detecting a corresponding current in the Li-containing semiconductor compound; and, in the second mode, the Li-containing semiconductor compound is coupled to a photodetector operable for detecting photons generated in the Li-containing semiconductor compound in the presence of the neutrons.

  6. A route to transparent bulk metals

    KAUST Repository

    Schwingenschlögl, Udo

    2012-07-23

    Hypothetical compounds based on a sapphire host are investigated with respect to their structural as well as electronic features. The results are obtained by electronic structure calculations within density functional theory and the generalized gradient approximation. A quarter of the Al atoms in Al 2O 3 is replaced by a 4d transition metal M ion, with d 0 to d 9 electronic configuration. We perform structure optimizations for all the compounds and analyze the electronic states. Due to the sizeable band gap of the Al 2O 3 host, we can identify promising candidates for transparent bulk metals. We explain the mechanisms leading to this combination of materials properties. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Vortices in superconducting bulk, films and SQUIDs

    Indian Academy of Sciences (India)

    Ernst Helmut Brandt

    2006-01-01

    The properties of the ideal periodic vortex lattice in bulk superconductors and in films of any thickness can be calculated from Ginzburg-Landau theory by an iteration method using Fourier series. The London theory yields general analytic expressions for the magnetic field and energy of arbitrary arrangements of straight or curved vortex lines. The elasticity of the vortex lattice is highly nonlocal. The magnetic response of superconductors of realistic shapes like thin and thick strips and disks or thin rectangular plates or films, containing pinned vortices, can be computed within continuum theory by solving an integral equation. A useful example is a thin square with a central hole and a radial slit, used as superconducting quantum interference device (SQUID).

  8. Combustion of bulk titanium in oxygen

    Science.gov (United States)

    Clark, A. F.; Moulder, J. C.; Runyan, C. C.

    1975-01-01

    The combustion of bulk titanium in one atmosphere oxygen is studied using laser ignition and several analytical techniques. These were high-speed color cinematography, time and space resolved spectra in the visible region, metallography (including SEM) of specimens quenched in argon gas, X-ray and chemical product analyses, and a new optical technique, the Hilbert transform method. The cinematographic application of this technique for visualizing phase objects in the combustion zone is described. The results indicate an initial vapor phase reaction immediately adjacent to the molten surface but as the oxygen uptake progresses the evaporation approaches the point of congruency and a much reduced evaporation rate. This and the accumulation of the various soluble oxides soon drive the reaction zone below the surface where gas formation causes boiling and ejection of particles. The buildup of rutile cuts off the oxygen supply and the reaction ceases.

  9. Tuneable film bulk acoustic wave resonators

    CERN Document Server

    Gevorgian, Spartak Sh; Vorobiev, Andrei K

    2013-01-01

    To handle many standards and ever increasing bandwidth requirements, large number of filters and switches are used in transceivers of modern wireless communications systems. It makes the cost, performance, form factor, and power consumption of these systems, including cellular phones, critical issues. At present, the fixed frequency filter banks based on Film Bulk Acoustic Resonators (FBAR) are regarded as one of the most promising technologies to address performance -form factor-cost issues. Even though the FBARs improve the overall performances the complexity of these systems remains high.  Attempts are being made to exclude some of the filters by bringing the digital signal processing (including channel selection) as close to the antennas as possible. However handling the increased interference levels is unrealistic for low-cost battery operated radios. Replacing fixed frequency filter banks by one tuneable filter is the most desired and widely considered scenario. As an example, development of the softwa...

  10. Charm mass effects in bulk channel correlations

    CERN Document Server

    Burnier, Y

    2013-01-01

    The bulk viscosity of thermalized QCD matter at temperatures above a few hundred MeV could be significantly influenced by charm quarks because their contribution arises four perturbative orders before purely gluonic effects. In an attempt to clarify the challenges of a lattice study, we determine the relevant imaginary-time correlator (of massive scalar densities) up to NLO in perturbation theory, and compare with existing data. We find discrepancies much larger than in the vector channel; this may hint, apart from the importance of taking a continuum limit, to larger non-perturbative effects in the scalar channel. We also recall how a transport peak related to the scalar density spectral function encodes non-perturbative information concerning the charm quark chemical equilibration rate close to equilibrium.

  11. Holographic bulk viscosity: GPR vs EO

    CERN Document Server

    Buchel, Alex; Kiritsis, Elias

    2011-01-01

    Recently Eling and Oz (EO) proposed a formula for the holographic bulk viscosity, in arXiv:1103.1657, derived from the null horizon focusing equation. This formula seems different from that obtained earlier by Gubser, Pufu and Rocha (GPR) in arXiv:0806.0407 calculated from the IR limit of the two-point function of the trace of the stress tensor. The two were shown to agree only for some simple scaling cases. We point out that the two formulae agree in two non-trivial holographic theories describing RG flows. The first is the strongly coupled N=2* gauge theory plasma. The second is the semi-phenomenological model of Improved Holographic QCD.

  12. Organic hybrid planar-nanocrystalline bulk heterojunctions

    Science.gov (United States)

    Forrest, Stephen R.; Yang, Fan

    2011-03-01

    A photosensitive optoelectronic device having an improved hybrid planar bulk heterojunction includes a plurality of photoconductive materials disposed between the anode and the cathode. The photoconductive materials include a first continuous layer of donor material and a second continuous layer of acceptor material. A first network of donor material or materials extends from the first continuous layer toward the second continuous layer, providing continuous pathways for conduction of holes to the first continuous layer. A second network of acceptor material or materials extends from the second continuous layer toward the first continuous layer, providing continuous pathways for conduction of electrons to the second continuous layer. The first network and the second network are interlaced with each other. At least one other photoconductive material is interspersed between the interlaced networks. This other photoconductive material or materials has an absorption spectra different from the donor and acceptor materials.

  13. A simple new competition assay for heparin binding in serum applied to multivalent PAMAM dendrimers.

    Science.gov (United States)

    Bromfield, Stephen M; Posocco, Paola; Fermeglia, Maurizio; Pricl, Sabrina; Rodríguez-López, Julián; Smith, David K

    2013-05-25

    We report a competition assay using our recently reported dye Mallard Blue, which allows us to identify synthetic heparin binders in competitive media, including human serum - using this we gain insight into the ability of PAMAM dendrimers to bind heparin, with the interesting result that low-generation G2-PAMAM is the preferred heparin binder.

  14. Grafted Cross-Linked Polyolefin Substrates for Peptide Synthesis and Assays

    DEFF Research Database (Denmark)

    1999-01-01

    suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words...

  15. Assessment of bioburden encapsulated in bulk materials

    Science.gov (United States)

    Schubert, Wayne W.; Newlin, Laura; Chung, Shirley Y.; Ellyin, Raymond

    2016-05-01

    The National Aeronautics and Space Administration (NASA) imposes bioburden limitations on all spacecraft destined for solar system bodies that might harbor evidence of extant or extinct life. The subset of microorganisms trapped within solid materials during manufacture and assembly is referred to as encapsulated bioburden. In the absence of spacecraft-specific data, NASA relies on specification values to estimate total spacecraft encapsulated bioburden, typically 30 endospores/cm3 or 300 viable cells/cm3 in non-electronic materials. Specification values for endospores have been established conservatively, and represent no less than an order of magnitude greater abundance than that derived from empirical assessments of actual spacecraft materials. The goal of this study was to generate data germane to determining whether revised bulk encapsulated material values (lower than those estimated by historical specifications) tailored specifically to the materials designated in modern-day spacecraft design could be used, on a case-by-case basis, to comply with planetary protection requirements. Organic materials having distinctly different chemical properties and configurations were selected. This required more than one experimental and analytical approach. Filtration was employed for liquid electrolytes, lubricants were suspended in an aqueous solution and solids (wire and epoxy sealant) were cryogenically milled. The final data characteristic for all bioburden estimates was microbial colony formation in rich agar growth medium. To assess survival potential, three non-spore-forming bacterial cell lines were systematically encapsulated in an epoxy matrix, liberated via cryogenic grinding, and cultured. Results suggest that bulk solid materials harbor significantly fewer encapsulated microorganisms than are estimated by specification values. Lithium-ion battery electrolyte reagents housed fewer than 1 CFU/cm3. Results also demonstrated that non-spore-forming microorganisms

  16. A spectrophotometric assay for the detection of fungal peroxygenases.

    Science.gov (United States)

    Poraj-Kobielska, Marzena; Kinne, Matthias; Ullrich, René; Scheibner, Katrin; Hofrichter, Martin

    2012-02-01

    Rapid and simple spectrophotometric methods are required for the unambiguous detection of recently discovered fungal peroxygenases in vivo and in vitro. This paper describes a peroxygenase-specific assay using 5-nitro-1,3-benzodioxole as substrate. The product, 4-nitrocatechol, produces a yellow color at pH 7, which can be followed over time at 425 nm (ε(425)=9,700 M(-1) cm(-1)), and a red color when adjusted to pH >12, which can be measured in form of an end-point determination at 514 nm (ε(514)=11,400 M(-1) cm(-1)). The assay is suitable for detecting peroxygenase activities in complex growth media and environmental samples as well as for high-throughput screenings.

  17. Media, Place, and Multiculturalism.

    Science.gov (United States)

    Meyrowitz, Joshua; Maguire, John

    1993-01-01

    Explores the role of television in American culture. America may be more diverse than ever in race, ethnicity, and religion, but, because of mass media, there is less diversity in experience, perspectives, and expectation. Subcultures that once manifested existence locally now look to television for verification of their existence. (SLD)

  18. Corruption in the Media

    NARCIS (Netherlands)

    Spence, Edward H.

    2009-01-01

    Using a general model of corruption that explains and accounts for corruption across different corporate and professional activities, the paper will examine how certain practices in the media, especially in areas where journalism, advertising and public relations regularly intersect and converge, ca

  19. Media and cultural identity

    Directory of Open Access Journals (Sweden)

    Necla Mora

    2008-03-01

    Full Text Available A society’s common cultural identity is the mainstay of a society’s definition. Socialization is the joining of the individual to the group activities, realizing the norms and to act in accordance with the exceptional behaviours. The most important factor to individual’s socializing is the structure of the society itself. The society, aspires, the individual who with the traditional behaviour go into to the socialization process into its ongoing social norms. Thus, the individual enters a learning process in which he/she acquires the essential knowledge. In a media based society the most common value judgement component is again media itself. The mass culture which is improving under the control of media is begun to produce as artificial, mono character and serial by the cultural industry which is also the producer and the protector of culture. Mass culture bombardment under the control of the cultural media separates, demolishes and alienates the public to their traditional culture. Social dissolution is shown itself by distorting or by eviscerating the common values, such as; traditions, customs and practices which make the society itself.

  20. Waves in inhomogeneous media

    NARCIS (Netherlands)

    Gerritsen, S.

    2007-01-01

    In this thesis we study wave propagation in inhomogeneous media. Examples of the classical (massless) waves we consider are acoustic waves (sound) and electromagnetic waves (light, for example). Interaction with inhomogeneities embedded in a reference medium alter the propagation direction, velocity

  1. Media for Enterobacteriaceae

    NARCIS (Netherlands)

    Mossel, D.A.A.

    1985-01-01

    The ‘rag-bag character of ‘coli-aerogenes’ bacteria used originally as markers for process failure has prompted their substitution by the taxonomically accurately delineated group of Enterobacteriaceae. Media previously used for the detection or enumeration of the coli-aerogenes group can be adapted

  2. Consolidating Social Media Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Munar, Ana Maria; Larson, Mia

    2014-01-01

    Gyimóthy & Larson (2014) portrayed three digital value co-creation strategies deployed by festival social media. Both frameworks provided novel analytical typologies which identified a series of categories (mimetic, analytic, immersion, advertising and insourcing, crowdsourcing and community consolidation...

  3. Islam and Media Representations

    Directory of Open Access Journals (Sweden)

    Mohamed Bensalah

    2006-04-01

    Full Text Available For the author of this article, the media’s treatment of Islam has raised numerous polymorphous questions and debates. Reactivated by the great scares of current events, the issue, though an ancient one, calls many things into question. By way of introduction, the author tries to analyse the complex processes of elaboration and perception of the representations that have prevailed during the past century. In referring to the semantic decoding of the abundant colonial literature and iconography, the author strives to translate the extreme xenophobic tensions and the identity crystallisations associated with the current media orchestration of Islam, both in theWest and the East. He then evokes the excesses of the media that are found at the origin of many amalgams wisely maintained between Islam, Islamism and Islamic terrorism, underscoring their duplicity and their willingness to put themselves, consciously, in service to deceivers and directors of awareness, who are very active at the heart of the politico-media sphere. After levelling a severe accusation against the harmful drifts of the media, especially in times of crisis and war, the author concludes by asserting that these tools of communication, once they are freed of their masks and invective apparatuses, can be re-appropriated by new words and bya true communication between peoples and cultures.

  4. Big Data, Small Media

    Directory of Open Access Journals (Sweden)

    Grant Bollmer

    2014-08-01

    Andrew Dubber Radio in the Digital Age Polity, Cambridge, 2013   Charles Ess Digital Media Ethics, Second Edition Polity, Cambridge, 2014   Graeme Kirkpatrick Computer Games and the Social Imaginary Polity, Cambridge, 2013   Dhiraj Murthy Twitter: Social Communication in the Twitter Age Polity, Cambrige, 2013   Jill Walker Rettberg Blogging, Second Edition Polity, Cambridge, 2014

  5. Femicide in media

    Directory of Open Access Journals (Sweden)

    Mršević Zorica

    2014-01-01

    Full Text Available Media in Serbia explain femicide usually as caused by poverty and alcoholism. This style is gender blind and socially stereotyped because of neglected gender aspects of male violence against women. Particular problem is lack of problematizing obvious social “permission” of male violence. Femicide is regularly presented as an incident, allegedly impossible for anticipation rather than tragic epilogue of long lasting male violence against women which as such exists as a part of traditional gender social relations and roles. Media overlook that alcohol and poverty may only contribute to intensification of already existing, widely accepted domination of men and subordination of women. Media reports as a rule didn’t enter deeper into problems of institutional and social context in which is perpetrated long lasting violence as prefacing femicide. Media also never criticize the social behavior of neighbors, relatives and all others informed on the domestic violence, but rather avoid „mixing“into privacy matters. Thus violence escalates without barriers, eventually developed in femicide, murder a woman, victim of this, decades long lasting violence.

  6. European media law

    NARCIS (Netherlands)

    Castendyk, O.; Dommering, E.; Scheuer, A.

    2008-01-01

    European Union legislation concerning electronic communications media is firmly established as an essential part of the law in the field in Europe. From relevant provisions of the European Convention of Human Rights and the EC Treaty to numerous directives, the most recent being the Audiovisual Medi

  7. Library Media Services Handbook.

    Science.gov (United States)

    Winnipeg School Div. Number 1, Manitoba (Canada).

    This 1991 edition of the handbook for Winnipeg School Division Number 1 school library media programs presents detailed program guidelines, objectives, philosophies, and goals in five major sections: (1) Library Policy and Practices (statement of the division's educational philosophy and goals, philosophy and goals of the division's library…

  8. Media for Multicultural Education.

    Science.gov (United States)

    Maestro-Scherer, Jane B.; And Others

    1979-01-01

    A cross-cultural course sequence at Iowa State University which offers a Third World cultural experience and introduces students to Third World views about such crucial world problems as population pressures, food supplies, and energy resources has a continuing need for media resources, e.g., films and slides. (CMV)

  9. Expanding Media Reach

    Centers for Disease Control (CDC) Podcasts

    2007-11-01

    In this podcast, two nurses serving a Chinese American community show how they have used local ethnic media to communicate health messages.  Created: 11/1/2007 by National Diabetes Education Program (NDEP), a joint program of the Centers for Disease Control and Prevention and the National Institutes of Health.   Date Released: 11/11/2007.

  10. Mass Media and Society.

    Science.gov (United States)

    Wells, Alan

    Designed to serve as a basic text for general liberal arts courses in mass communication, this book presents essays, largely from recent magazine articles, written from the layman (although there are a few more overtly scholarly articles). It begins with an examination of the media industries in the United States, treating them as complex…

  11. The Media Works.

    Science.gov (United States)

    Valdes, Joan; Crow, Jeanne

    This student text and activity book provides information on and suggests ways to examine seven of the mass media: movies, television, advertising, magazines, comics, radio, and newspapers. Much of the learning takes place by actual examination of actual products to learn characteristics common to them. The first section investigates the process of…

  12. Digital media ethics

    DEFF Research Database (Denmark)

    Ess, Charles

    Designed as both a teaching text and reader for students and faculty across diverse disciplines, the book provides an "ethical toolkit" - an introduction to prevailing ethical frameworks - and shows their application to both general issues and specific case-studies in digital media (privacy...

  13. Ethics and media

    Directory of Open Access Journals (Sweden)

    Freddy Álvarez

    2008-06-01

    Full Text Available Preguntarse por la ética y los Mass Media,no es fácil. Es una interpelación impregnada de complejidad por la pluralidad de los Media, unida a la dificultad para entender un fenómeno relativamente actual. Además, para lograr acercarnos a una repuesta seria y profunda es importante replantear la ética de otro modo. Los Media, en tanto que tecnologías, como todas las ciencias, debido a la influencia del cartesianismo, han estado fuera de toda relación ética. Quienes los manejan, todavía creen que por pretender a la objetividad y a la neutralidad ya están en la ética. Veamos un poco las derivas en las que ingresan los Media a causa de su disyunción con la ética y los grandes olvidos en los que ha caído, sobre todo en lo que se refiere a la ética y a la verdad.

  14. Media challenging capitalism

    DEFF Research Database (Denmark)

    Sandvik, Kjetil

    Digital media and especially so-called ‘social media’ have on the one hand been ascribed the power to change societies and empower democratic movements following the thoughts of e.g. Rheingold (2004), recently fueled by the democratic uprising in Arabic countries such as Egypt, Tunisia, Iran and ...

  15. Cyberbullying via Social Media

    Science.gov (United States)

    Whittaker, Elizabeth; Kowalski, Robin M.

    2015-01-01

    Recent years have witnessed a surge of research on cyberbullying. In this article, three studies examined prevalence rates of cyberbullying among college-age students, venues through which cyberbullying occurs, with a particular focus on social media, and perceptions of cyberbullying as a function of features of the target (e.g., peer, celebrity,…

  16. News Media Industry

    Science.gov (United States)

    2006-01-01

    transform the way Americans receive news and information. But Saul Hansell of the New York Times believes none of this is a surprise to the media elites...References Anderson, B. (2004). “News Flash: Journalism, Infotainment and the Bottom-Line Business of Broadcast News.” Jossey- Bass , pp

  17. Social Media in Organizations

    DEFF Research Database (Denmark)

    Razmerita, Liana; Kirchner, Kathrin; Nabeth, Thierry

    2014-01-01

    By using social media, many companies try to exploit new forms of interaction, collaboration, and knowledge sharing through leveraging the social, collaborative dimension of social software. The traditional collective knowledge management model based on a top-down approach is now opening up new a...

  18. Barcoded microchips for biomolecular assays.

    Science.gov (United States)

    Zhang, Yi; Sun, Jiashu; Zou, Yu; Chen, Wenwen; Zhang, Wei; Xi, Jianzhong Jeff; Jiang, Xingyu

    2015-01-20

    Multiplexed assay of analytes is of great importance for clinical diagnostics and other analytical applications. Barcode-based bioassays with the ability to encode and decode may realize this goal in a straightforward and consistent manner. We present here a microfluidic barcoded chip containing several sets of microchannels with different widths, imitating the commonly used barcode. A single barcoded microchip can carry out tens of individual protein/nucleic acid assays (encode) and immediately yield all assay results by a portable barcode reader or a smartphone (decode). The applicability of a barcoded microchip is demonstrated by human immunodeficiency virus (HIV) immunoassays for simultaneous detection of three targets (anti-gp41 antibody, anti-gp120 antibody, and anti-gp36 antibody) from six human serum samples. We can also determine seven pathogen-specific oligonucleotides by a single chip containing both positive and negative controls.

  19. Radioreceptor assay method for insulin

    Energy Technology Data Exchange (ETDEWEB)

    Mori, K.F.; Wood, R.J. (Bureau of Drug Research, Health and Welfare Canada, Ottawa, Ontario. Health Protection Branch)

    1984-01-01

    A sensitive practical radioreceptor assay method for pharmaceutical insulin products has been developed with partially purified rat liver plasma membranes and the optimal conditions under which the best overall assay performance is obtainable have been defined. Intra- and inter-assay variations of the method averaged 7.3 and 12.2% of the man, respectively, when expressed as the coefficient of variation. Potency estimates of an insulin product obtained with the proposed method correlated well with those determined by the mouse convulsion bioassay method. Liver membranes prepared according to the method could be stored for up to ten weeks at 4/sup 0/C and for 6 months or more at -18/sup 0/C without losing insulin-binding ability.

  20. Trolling New Media: Violent Extremist Groups Recruiting Through Social Media

    Science.gov (United States)

    2015-12-01

    violent extremist groups have adapted their communication structures to utilize social media networks for distributing propaganda, biased information...technologies and social 5 “Internet Seen as Positive Influence on Education but Negative Influence on...Twitter.36 In addition to social media site preferences, the Center also conducted a separate study to determine why users joined social media networks

  1. Media Now: A Historical Review of a Media Literacy Curriculum

    Science.gov (United States)

    Friesem, Yonty; Quaglia, Diane; Crane, Ed

    2014-01-01

    The Elizabeth Thoman Archive at the Harrington School of Communication and Media, University of Rhode Island, has the last complete kit of one of the milestones in the early chronology of media literacy, the 1972 Media Now curriculum. This curriculum was the first of its kind, using self-contained lesson modules that were part of a larger series…

  2. Enrichment of sulfate-reducing bacteria and resulting mineral formation in media mimicking pore water metal ion concentrations and pH conditions of acidic pit lakes.

    Science.gov (United States)

    Meier, Jutta; Piva, Angela; Fortin, Danielle

    2012-01-01

    Acid mine drainage sites are extreme environments with high acidity and metal ion concentrations. Under anoxic conditions, microbial sulfate reduction may trigger the formation of secondary minerals as a result of H2S production and pH increase. This process was studied in batch experiments with enrichment cultures from acidic sediments of a pit lake using growth media set at different pH values and containing elevated concentrations of Fe²⁺ and Al³⁺. At initial pH values of 5 and 6, sulfate reduction occurred shortly after inoculation. Sulfate- reducing bacteria affiliated to the genus Desulfosporosinus predominated the microbial communities as shown by 16S rRNA gene analysis performed at the end of the incubation. At initial pH values of 3 and 4, sulfate reduction and cell growth occurred only after an extended lag phase, however, at a higher rate than in the less acidic assays. At the end of the growth phase, enrichments were dominated by Thermodesulfobium spp. suggesting that these sulfate reducers were better adapted to acidic conditions. Iron sulfides in the bulk phase were common in all assays, but specific aluminum precipitates formed in close association with cell surfaces and may function as a detoxification mechanism of dissolved Al species at low pH.

  3. Editorial: Pedagogical Media Ecologies

    Directory of Open Access Journals (Sweden)

    Dorothee M. Meister

    2014-07-01

    Full Text Available From educational gaming through portable e-readers to cell phones, media are interpenetrating educational spaces and activities. Accordingly, understanding media in environmental or ecological terms has become increasingly important for education internationally. In North America, for example, the centenary of McLuhan’s birth has focused attention on approaches to media – whether oral, textual, electronic or digital– as a kind of environment in which education takes place. In parts of Europe, the so-called mediatic turn – following on the linguistic and iconic turns – has similarly emphasized the role of media as a condition for the possibility of educational activities and programs. With a few exceptions1 the papers in this special issue were first presented at the conference «Educational Media Ecologies: International Perspectives» which took place at the University of Paderborn, Germany, on March 27–28, 2012.2 The event was an interdisciplinary and transatlantic endeavor to bring together a wide range of perspectives on various issues relevant to educational media ecologies,3 and on related debates on mediation, medialization, mediatization, and mediality.4 The purpose of this volume, like the conference, is to foster and deepen international dialogue in the area of educational media. Areas of research and scholarship relevant to this dialogue include educational media, media literacy, educational philosophy, and media and cultural studies. The contributions, described below, put conceptual issues as well as social practices and applications at the center of the debate. Klaus Rummler opens the issue by clarifying the concept of ecology itself. Referencing a range of work over the past 50 years, Rummler describes how ecological models have been cast in sociological, semiotic, cultural, mediatic and other terms, and he explains the implications of these various perspectives for the study of educational contexts. Rummler also

  4. Media independence and dividend policy

    DEFF Research Database (Denmark)

    Farooq, Omar; Dandoune, Salma

    2012-01-01

    independence and dividend policies in emerging markets. Using a dataset from twenty three emerging markets, we show a significantly negative relationship between dividend policies (payout ratio and decision to pay dividend) and media independence. We argue that independent media reduces information asymmetries...... for stock market participants. Consequently, stock market participants in emerging markets with more independent media do not demand as high and as much dividends as their counterparts in emerging markets with less independent media. We also show that press independence is more important in defining......Can media pressurize managers to disgorge excess cash to shareholders? Do firms in countries with more independent media follow different dividend policies than firms with less independent media? This paper seeks to answer these questions and aims to document the relationship between media...

  5. DISKURSUS ISLAM DALAM KONSTRUKSI MEDIA

    Directory of Open Access Journals (Sweden)

    Muhammad Fahmi

    2015-12-01

    Full Text Available This paper aims to examine how the secular media in Surakarta represent Islam in the case of Charlie Hebdo. Therefore, this study used discourse analysis of Theo van Leeuwen focusing on how the subject or actor of the show in the media. This study concluded that the media represent Islam not only with “Western ideology” through idioms such as radical Islamist militants and terrorists, but also with "Islamic ideology". It is done through the construction of Islam as a religion of moderation and delegitimize Charlie Hebdo as magazine satyr abusing freedom. Various strategies are used ranging from strategy passivation to interdetermination. In this case, there are two poles of attraction in both media, namely the Western and Islamic ideology. If both media are quoting from Western sources, the Western ideology dominates the media narrative. Conversely, when both media used Islamic sources, the influence of Islamic ideology dominates the narrative of both media.

  6. Children and the Mass Media

    Science.gov (United States)

    Winston, Shirley

    1970-01-01

    Resume of testimony given at hearings at the White House Conference on Children, September, 1970. Topics considered were the influence of the mass media on children and ways to improve media products. (NH)

  7. Media life of the young

    DEFF Research Database (Denmark)

    Westlund, Oscar; Bjur, Jakob

    2014-01-01

    This is a thorough investigation into contemporary young people and their media life. The article conceptualizes a typology of media life, drawing on a theoretical body involving the sociology of generations, life course research, media life and individualization. This empirically derived typology...... makes a strong instrument for an understanding of the media life of the young, furnishing insights into how they have constructed their use of media. The investigation is based on a robust national survey with Swedes born 1994–2001, conducted in 2010, and focusing on four media: television, gaming......, the Internet and mobile devices. Two of the findings are particularly surprising. Firstly, the results reveal that the young generally lead heterogeneous media lives, varying with age and sex. Secondly, although some young people literarily live their life in media, there are also de facto young who live...

  8. Performance and applications of quench melt-growth bulk magnets

    Science.gov (United States)

    Nariki, S.; Teshima, H.; Morita, M.

    2016-03-01

    This paper describes the progress in quench melt-growth (QMG) bulk magnets, developed by the Nippon Steel & Sumitomo Metal Corporation, which consist of single crystalline RE123 phase and finely dispersed RE211 particles. QMG bulks can trap high magnetic fields. The field-trapping ability of QMG bulks is largely increased with an improvement in its J c and size, promising the realization of various applications such as flywheel energy-storage systems, ship motors, NMR/MRI spectrometers, wind-power generators and so on. Intensive research has revealed that the optimal RE element is different depending on application requirements. Gd-QMG bulk is the most promising material for several high-field engineering applications. The trapped magnetic field of Gd-QMG bulk 60 mm in diameter at 77 K is twice as large as that of Y-QMG bulk with a similar size due to its excellent J c properties. The large Gd-based QMG bulks up to 150 mm in diameter are fabricated by incorporating the RE compositional gradient method. Compact NMR/MRI spectrometers are one of the promising applications of bulk superconductors. Eu-QMG bulks are suitable for NMR magnets. NMR applications require extremely homogeneous magnetic fields. In the Eu-system, the small paramagnetic moment of a Eu ion compared to a Gd ion improves the field homogeneity in the bulk. For the application of current leads, Dy-based QMG is available by utilizing a low thermal conductivity.

  9. Data Mining in Social Media

    Science.gov (United States)

    Barbier, Geoffrey; Liu, Huan

    The rise of online social media is providing a wealth of social network data. Data mining techniques provide researchers and practitioners the tools needed to analyze large, complex, and frequently changing social media data. This chapter introduces the basics of data mining, reviews social media, discusses how to mine social media data, and highlights some illustrative examples with an emphasis on social networking sites and blogs.

  10. Going Public on Social Media

    Directory of Open Access Journals (Sweden)

    Greg Elmer

    2015-04-01

    Full Text Available This brief essay questions the disconnect between the financial goals of social media properties and the concerns of privacy advocates and other new media critics. It is argued that critics of social media often fail to recognize the financial imperative of social media companies, one that requires users to divulge and publicize ever more granular aspects of their daily lives, thoughts, and feelings.

  11. Competition and Commercial Media Bias

    OpenAIRE

    A. Blasco; F. Sobbrio

    2011-01-01

    This paper reviews the empirical evidence on commercial media bias (i.e., advertisers influence over media accuracy) and then introduces a simple model to summarize the main elements of the theoretical literature. The analysis provides three main policy insights for media regulators: i) Media regulators should target their monitoring efforts towards news contents upon which advertisers are likely to share similar preferences; ii) In advertising industries characterized by high correlation in ...

  12. The Weaponization of Social Media

    Science.gov (United States)

    2016-06-10

    proven to be extremely adept at using social media to its advantage . Twitter and the Islamic State To understand the Islamic State’s use of Social ... media efforts will be compared to similar Western business and civic social media centric marketing efforts from both a technical and theoretical...opinion on domestic policy issues using social media to gain an advantage . While the example of the White House’s Thunderclap campaign ended in failure

  13. Documentary Media and Religious Communities

    Directory of Open Access Journals (Sweden)

    Marie-Therese Mäder

    2015-11-01

    Full Text Available The article considers four spaces where media processes involve religious communities and agents: the spaces of production, of representation, of media communication, and of distribution network and institutional framework for circulation. These three spaces systematise the research question posed to the specific source. Furthermore the concept documentary media as viewed from a semio-pragmatic perspective is introduced. Discussion of the commercial series I’m a Mormon shows how different modes define documentary media according to the three spaces.

  14. [Media for 21st century--towards human communication media].

    Science.gov (United States)

    Harashima, H

    2000-05-01

    Today, with the approach of the 21st century, attention is focused on multi-media communications combining computer, visual and audio technologies. This article discusses the communication media target and the technological problems constituting the nucleus of multi-media. The communication media is becoming an environment from which no one can escape. Since the media has such a great power, what is needed now is not to predict the future technologies, but to estimate the future world and take to responsibility for future environments.

  15. Transmedia Play: Literacy across Media

    Science.gov (United States)

    Alper, Meryl; Herr-Stephenson, Rebecca

    2013-01-01

    Transmedia play is a new way to understand how children develop critical media literacy and new media literacies through their interactions with contemporary media that links stories and structures across platforms. This essay highlights five characteristics of transmedia play that make it particularly useful for learning:…

  16. Media Competition and Electoral Politics

    NARCIS (Netherlands)

    Piolatto, A.; Schuett, F.

    2013-01-01

    Abstract: We build a framework linking competition in the media market to political participation, media slant, and selection of politicians. Media outlets report on the ability of candidates running for office and compete for audience through their choice of slant. Citizens derive utility from foll

  17. Media Violence and Young People.

    Science.gov (United States)

    Oaks, Harold R.

    1995-01-01

    Discusses the possibility of a connection between violence in the media and actual adolescent behavior. Explores the nature of the connection, why it exists, and possible courses of action to correct the problem. States that 3,000 studies have explored the link between media violence and adolescent behavior. Concludes that the media should show…

  18. Characterizing Government Social Media Research

    DEFF Research Database (Denmark)

    Medaglia, Rony; Zheng, Lei

    2016-01-01

    As research on government social media continues to grow in quantity and scope, this area calls for mapping and systematization, in order to stimulate better-informed studies in the future. This paper draws on a comprehensive review of government social media literature in the e...... a four-point research agenda for future government social media research....

  19. Towards Fashion Media for Sustainability

    DEFF Research Database (Denmark)

    Skjold, Else

    2015-01-01

    Throughout the chapter, it is pointed out how fashion media traditionally fuel on unsustainable imbalances of self, in terms of affluence, gender, ethnicity, body types and age. The chapter opens with a historic outline. Here, the close alliance between media and industry is problematized, whilst...... establishing more sustainable fashion media in the future....

  20. Media Literacy. Technical Assistance Packet.

    Science.gov (United States)

    Join Together, Boston, MA.

    The media play an increasingly strong role in transmitting values; behaviors; social norms; attitudes; and knowledge to youth and adults. Media literacy involves the ability to ask questions about what is watched, heard, or read. It involves learning what to look for, what to ask, and how to question these many influences. Media literacy also…

  1. Chromosome aberration assays in Allium

    Energy Technology Data Exchange (ETDEWEB)

    Grant, W.F.

    1982-01-01

    The common onion (Allium cepa) is an excellent plant for the assay of chromosome aberrations after chemical treatment. Other species of Allium (A. cepa var. proliferum, A. carinatum, A. fistulosum and A. sativum) have also been used but to a much lesser extent. Protocols have been given for using root tips from either bulbs or seeds of Allium cepa to study the cytological end-points, such as chromosome breaks and exchanges, which follow the testing of chemicals in somatic cells. It is considered that both mitotic and meiotic end-points should be used to a greater extent in assaying the cytogenetic effects of a chemical. From a literature survey, 148 chemicals are tabulated that have been assayed in 164 Allium tests for their clastogenic effect. Of the 164 assays which have been carried out, 75 are reported as giving a positive reaction, 49 positive and with a dose response, 1 positive and temperature-related, 9 borderline positive, and 30 negative; 76% of the chemicals gave a definite positive response. It is proposed that the Allium test be included among those tests routinely used for assessing chromosomal damage induced by chemicals.

  2. Disagreement between Human Papillomavirus Assays

    DEFF Research Database (Denmark)

    Rebolj, Matejka; Preisler, Sarah; Ejegod, Ditte Møller;

    2014-01-01

    We aimed to determine the disagreement in primary cervical screening between four human papillomavirus assays: Hybrid Capture 2, cobas, CLART, and APTIMA. Material from 5,064 SurePath samples of women participating in routine cervical screening in Copenhagen, Denmark, was tested with the four ass...

  3. Stereotypes in media and media literacy among young people

    Directory of Open Access Journals (Sweden)

    Đerić Ivana

    2006-01-01

    Full Text Available Young people, the most common consumers of media content, bear out the view that media shapes people’s lives. Therefore we must not underestimate the effect media exerts on young people’s values and behavioral patterns. Television is the medium which draws children and young people for the greatest part of their free time. Regardless whether television programs are described as positive or negative, whether they abound with stereotypes or not, it is important that young people develop a critical attitude towards them so that they may resist different forms of media manipulation. The paper discusses how stereotypes are generated and used by media and the manners in which stereotypical concepts affect young people’s attitudes. It highlights the importance of the development of media literacy which implies a critical attitude towards media images and discourses, the development of criteria for the selection and evaluation of information broadcast by media, the development of skills in interpreting and understanding stereotypical concepts and familiarity with alternative forms of media culture. The paper draws special attention to the issue of media education. The conclusion is that schools should offer media literacy as part of their curriculum and in it possible solutions to the problems discussed. .

  4. Force transmission in cohesive granular media

    Science.gov (United States)

    Radjai, Farhang; Topin, Vincent; Richefeu, Vincent; Voivret, Charles; Delenne, Jean-Yves; Azéma, Emilien; El Youssoufi, Said

    2010-05-01

    We use numerical simulations to investigate force and stress transmission in cohesive granular media covering a wide class of materials encountered in nature and industrial processing. The cohesion results either from capillary bridges between particles or from the presence of a solid binding matrix filling fully or partially the interstitial space. The liquid bonding is treated by implementing a capillary force law within a debonding distance between particles and simulated by the discrete element method. The solid binding matrix is treated by means of the Lattice Element Method (LEM) based on a lattice-type discretization of the particles and matrix. Our data indicate that the exponential fall-off of strong compressive forces is a generic feature of both cohesive and noncohesive granular media both for liquid and solid bonding. The tensile forces exhibit a similar decreasing exponential distribution, suggesting that this form basically reflects granular disorder. This is consistent with the finding that not only the contact forces but also the stress components in the bulk of the particles and matrix, accessible from LEM simulations in the case of solid bonding, show an exponential fall-off. We also find that the distribution of weak compressive forces is sensitive to packing anisotropy, particle shape and particle size distribution. In the case of wet packings, we analyze the self-equilibrated forces induced by liquid bonds and show that the positive and negative particle pressures form a bi-percolating structure.

  5. Gravitational potential wells and the cosmic bulk flow

    CERN Document Server

    Kumar, Abhinav; Feldman, Hume A; Watkins, Richard

    2015-01-01

    The bulk flow is a volume average of the peculiar velocities and a useful probe of the mass distribution on large scales. The gravitational instability model views the bulk flow as a potential flow that obeys a Maxwellian Distribution. We use two N-body simulations, the LasDamas Carmen and the Horizon Run, to calculate the bulk flows of various sized volumes in the simulation boxes. Once we have the bulk flow velocities as a function of scale, we investigate the mass and gravitational potential distribution around the volume. We found that matter densities can be asymmetrical and difficult to detect in real surveys, however, the gravitational potential and its gradient may provide better tools to investigate the underlying matter distribution. This study shows that bulk flows are indeed potential flows and thus provides information on the flow sources. We also show that bulk flow magnitudes follow a Maxwellian distribution on scales $>10\\ h^{-1}$Mpc.

  6. A CFT Perspective on Gravitational Dressing and Bulk Locality

    CERN Document Server

    Lewkowycz, Aitor; Verlinde, Herman

    2016-01-01

    We revisit the construction of local bulk operators in AdS/CFT with special focus on gravitational dressing and its consequences for bulk locality. Specializing to 2+1-dimensions, we investigate these issues via the proposed identification between bulk operators and cross-cap boundary states. We obtain explicit expressions for correlation functions of bulk fields with boundary stress tensor insertions, and find that they are free of non-local branch cuts but do have non-local poles. We recover the HKLL recipe for restoring bulk locality for interacting fields as the outcome of a natural CFT crossing condition. We show that, in a suitable gauge, the cross-cap states solve the bulk wave equation for general background geometries, and satisfy a conformal Ward identity analogous to a soft graviton theorem, Virasoro symmetry, the large N conformal bootstrap and the uniformization theorem all play a key role in our derivations.

  7. Finsler geometric perspective on the bulk flow in the universe

    CERN Document Server

    Cahng, Zhe; Wang, Sai

    2013-01-01

    Astronomical observations showed that there exists a bulk flow with peculiar velocities in the universe, which contradicts with the (\\Lambda)CDM model. The bulk flow reveals that the observational universe is anisotropic at large scales. In this paper, we propose a "wind" scenario to the bulk flow. Under the influence of the "wind", the spacetime metric could become a Finsler structure. By resolving the null geodesic equation, we obtain the modified luminosity distance, which has a dipolar form at the leading order. Thus, the "wind" describes well the bulk flow. In addition, we perform a least-(\\chi^2) fit to the data of type Ia supernovae (SNe Ia) in the Union2.1 compilation. The peculiar velocity of the bulk flow has an upper limit (v_{bulk}\\lesssim 4000 \\rm{km/s}), which is compatible with all the existing observational values.

  8. Macroscopic and direct light propulsion of bulk graphene material

    CERN Document Server

    Zhang, Tengfei; Wu, Yingpeng; Xiao, Peishuang; Yi, Ningbo; Lu, Yanhong; Ma, Yanfeng; Huang, Yi; Zhao, Kai; Yan, Xiao-Qing; Liu, Zhi-Bo; Tian, Jian-Guo; Chen, Yongsheng

    2015-01-01

    It has been a great challenge to achieve the direct light manipulation of matter on a bulk scale. In this work, the direct light propulsion of matter was observed on a macroscopic scale for the first time using a bulk graphene based material. The unique structure and properties of graphene and the morphology of the bulk graphene material make it capable of not only absorbing light at various wavelengths but also emitting energetic electrons efficiently enough to drive the bulk material following Newtonian mechanics. Thus, the unique photonic and electronic properties of individual graphene sheets are manifested in the response of the bulk state. These results offer an exciting opportunity to bring about bulk scale light manipulation with the potential to realize long-sought proposals in areas such as the solar sail and space transportation driven directly by sunlight.

  9. Bulk Glassy Alloys: Historical Development and Current Research

    Directory of Open Access Journals (Sweden)

    Akihisa Inoue

    2015-06-01

    Full Text Available This paper reviews the development of current research in bulk glassy alloys by focusing on the trigger point for the synthesis of the first bulk glassy alloys by the conventional mold casting method. This review covers the background, discovery, characteristics, and applications of bulk glassy alloys, as well as recent topics regarding them. Applications of bulk glassy alloys have been expanding, particularly for Fe-based bulk glassy alloys, due to their unique properties, high glass-forming ability, and low cost. In the near future, the engineering importance of bulk glassy alloys is expected to increase steadily, and continuous interest in these novel metallic materials for basic science research is anticipated.

  10. A space-time analysis of Mycoplasma bovis: bulk tank milk antibody screening results from all Danish dairy herds in 2013-2014

    DEFF Research Database (Denmark)

    Arede, Margarida; Nielsen, Per Kantsø; Ahmed, Syed Sayeem Uddin;

    2016-01-01

    , using the indirect BIO K 302 M. bovis enzyme-linked immunosorbent assay (ELISA) (Bio-X, Belgium) in bulk tank milk from all dairy herds between June 2013 and July 2014. The objective of this study was to investigate the evolution of the spatial distribution of M. bovis in the Danish dairy herd...

  11. Recent developments of film bulk acoustic resonators

    Science.gov (United States)

    Gao, Junning; Liu, Guorong; Li, Jie; Li, Guoqiang

    2016-06-01

    Film bulk acoustic wave resonator (FBAR) experienced skyrocketing development in the past 15 years, owing to the explosive development of mobile communication. It stands out in acoustic filters mainly because of high quality factor, which enables low insertion loss and sharp roll off. Except for the massive application in wireless communication, FBARs are also promising sensors because of the high sensitivity and readily integration ability to miniaturize circuits. On the ground of summarizing FBAR’s application in wireless communication as filters and in sensors including electronic nose, bio field, and pressure sensing, this paper review the main challenges of each application faced. The number of filters installed in the mobile phone has being grown explosively, which leads to overcrowded bands and put harsh requirements on component size and power consumption control for each unit. Data flow and rate are becoming increasingly demanding as well. This paper discusses three promising technical strategies addressing these issues. Among which coupled resonator filter is given intense attention because it is able to vigorously reduce the filter size by stacking two or more resonators together, and it is a great technique to increase data flow and rate. Temperature compensation methods are discussed considering their vital influence on frequency stability. Finally, materials improvement and novel materials exploration for band width modulation, tunable band acquisition, and quality factor improvement are discussed. The authors appeal attention of the academic society to bring AlN epitaxial thin film into the FBAR fabrication and have proposed a configuration to implement this idea.

  12. Fault current limiter using bulk oxides superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Belmont, O.; Ferracci, P.; Porcar, L.; Barbut, J.M. [Schneider Electric, Grenoble (France). Usine A3; Tixador, P.; Noudem, J.G.; Bourgault, D.; Tournier, R

    1998-08-01

    We study the limitation possibilities of bulk Bi high T{sub c} materials. For this we test these materials with AC or DC currents above their critical currents. We study particularly the evolution of the voltage with time or with current. The material, the value of the current and the time duration play important parts. For sintered Bi samples the voltage depends only on the current even for values much larger than the critical current. With textured samples the V(I) curves shows an hysteretic behaviour due to a warming up. The textured materials are more interesting than sintered ones in terms of required volume for the current limitation. In both cases the superconductors are in a dissipative state but not in the normal state. This state is nevertheless reached if the dissipated energy inside the sample is sufficient. We have tried to apply a magnetic field on the samples in order to trigger a more effective limitation. The voltage increases but with a limited effect for currents much higher (3-4 times) than the critical zero field current. We think that the dissipative state is due mainly to the grain boundaries which become resistive above the critical current. (orig.) 11 refs.

  13. On methods of estimating cosmological bulk flows

    CERN Document Server

    Nusser, Adi

    2015-01-01

    We explore similarities and differences between several estimators of the cosmological bulk flow, $\\bf B$, from the observed radial peculiar velocities of galaxies. A distinction is made between two theoretical definitions of $\\bf B$ as a dipole moment of the velocity field weighted by a radial window function. One definition involves the three dimensional (3D) peculiar velocity, while the other is based on its radial component alone. Different methods attempt at inferring $\\bf B$ for either of these definitions which coincide only for a constant velocity field. We focus on the Wiener Filtering (WF, Hoffman et al. 2015) and the Constrained Minimum Variance (CMV,Feldman et al. 2010) methodologies. Both methodologies require a prior expressed in terms of the radial velocity correlation function. Hoffman et al. compute $\\bf B$ in Top-Hat windows from a WF realization of the 3D peculiar velocity field. Feldman et al. infer $\\bf B$ directly from the observed velocities for the second definition of $\\bf B$. The WF ...

  14. Determination of Bulk Dimensional Variation in Castings

    Energy Technology Data Exchange (ETDEWEB)

    Dr. James F. Cuttino Dr. Edward P. Morse

    2005-04-14

    The purpose of this work is to improve the efficiency of green sand foundries so that they may continue to compete as the most cost-effective method of fabrication while meeting tightening constraints on near-net shape manufacturing. In order to achieve this objective, the study is divided into two major components. The first component concentrated on identifying which processes control surface finish on the castings and which provide potential reductions in variations. The second component identified metrological methods that effectively discern between the geometry of bulk material versus surface finish in order to more accurately determine the quality of a part. The research resulted in the determination of an empirical relationship relating pouring parameters to dimensional variation, with an R2 value of greater than 0.79. A significant difference in variations obtained from vertical vs. horizontal molding machines was also noticed. When analyzed separately, however, the resulting empirical relationships for horizontal and vertical machines had reduced R2 values, probably due to the reduced data sets. Significant parameters when considering vertical and horizontal molding machines together included surface roughness, pattern type, iron type, pouring rate, copper content, amount of Western Bentonite, and permeability.

  15. Material Profile Influences in Bulk-Heterojunctions

    Energy Technology Data Exchange (ETDEWEB)

    Roehling, John D.; Rochester, Christopher W.; Ro, Hyun W.; Wang, Peng; Majewski, Jaroslaw; Batenburg, Kees J.; Arslan, Ilke; Delongchamp, Dean M.; Moule, Adam J.

    2014-10-01

    he morphology in mixed bulk-heterojunction films are compared using three different quantitative measurement techniques. We compare the vertical composition changes using high-angle annular dark-field scanning transmission electron microscopy with electron tomography and neutron and x-ray reflectometry. The three measurement techniques yield qualita-tively comparable vertical concentration measurements. The presence of a metal cathode during thermal annealing is observed to alter the fullerene concentration throughout the thickness of the film for all measurements. However, the abso-lute vertical concentration of fullerene is quantitatively different for the three measurements. The origin of the quantitative measurement differences is discussed. The authors thank Luna Innovations, Inc. for donating the endohedral fullerenes used in this study and Plextronics for the P3HT. They are gratefully thank the National Science Foundation Energy for Sustainability Program, Award No. 0933435. This work benefited from the use of the Lujan Neutron Scattering Center at Los Alamos Neutron Science Center funded by the DOE Office of Basic Energy Sciences and Los Alamos National Laboratory under DOE Contract DE-AC52-06NA25396. This research was also supported in part by Laboratory Directed Research & Development program at PNNL. The Pacific Northwest National Laboratory is operated by Battelle for the US Department of Energy under contract DE-AC05-76RL01830.

  16. Failure Prediction in Bulk Metal Forming Process

    Directory of Open Access Journals (Sweden)

    Ameen Topa

    2014-01-01

    Full Text Available An important concern in metal forming is whether the desired deformation can be accomplished without defects in the final product. Various ductile fracture criteria have been developed and experimentally verified for a limited number of cases of metal forming processes. These criteria are highly dependent on the geometry of the workpiece and cannot be utilized for complicated shapes without experimental verification. However, experimental work is a resource hungry process. This paper proposes the ability of finite element analysis (FEA software such as LS-DYNA to pinpoint the crack-like flaws in bulk metal forming products. Two different approaches named as arbitrary Lagrangian-Eulerian (ALE and smooth particle hydrodynamics (SPH formulations were adopted. The results of the simulations agree well with the experimental work and a comparison between the two formulations has been carried out. Both approximation methods successfully predicted the flow of workpiece material (plastic deformation. However ALE method was able to pinpoint the location of the flaws.

  17. Photoelectron spectroscopy bulk and surface electronic structures

    CERN Document Server

    Suga, Shigemasa

    2014-01-01

    Photoelectron spectroscopy is now becoming more and more required to investigate electronic structures of various solid materials in the bulk, on surfaces as well as at buried interfaces. The energy resolution was much improved in the last decade down to 1 meV in the low photon energy region. Now this technique is available from a few eV up to 10 keV by use of lasers, electron cyclotron resonance lamps in addition to synchrotron radiation and X-ray tubes. High resolution angle resolved photoelectron spectroscopy (ARPES) is now widely applied to band mapping of materials. It attracts a wide attention from both fundamental science and material engineering. Studies of the dynamics of excited states are feasible by time of flight spectroscopy with fully utilizing the pulse structures of synchrotron radiation as well as lasers including the free electron lasers (FEL). Spin resolved studies also made dramatic progress by using higher efficiency spin detectors and two dimensional spin detectors. Polarization depend...

  18. Thermodynamic properties of bulk and confined water

    Energy Technology Data Exchange (ETDEWEB)

    Mallamace, Francesco, E-mail: francesco.mallamace@unime.it [Dipartimento di Fisica e Scienza della Terra Università di Messina and CNISM, I-98168 Messina (Italy); Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215 (United States); Corsaro, Carmelo [Dipartimento di Fisica e Scienza della Terra Università di Messina and CNISM, I-98168 Messina (Italy); Mallamace, Domenico [Dipartimento di Scienze dell' Ambiente, della Sicurezza, del Territorio, degli Alimenti e della Salute, Università di Messina, I-98166 Messina (Italy); Vasi, Sebastiano; Vasi, Cirino [IPCF-CNR, I-98166 Messina (Italy); Stanley, H. Eugene [Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215 (United States)

    2014-11-14

    The thermodynamic response functions of water display anomalous behaviors. We study these anomalous behaviors in bulk and confined water. We use nuclear magnetic resonance (NMR) to examine the configurational specific heat and the transport parameters in both the thermal stable and the metastable supercooled phases. The data we obtain suggest that there is a behavior common to both phases: that the dynamics of water exhibit two singular temperatures belonging to the supercooled and the stable phase, respectively. One is the dynamic fragile-to-strong crossover temperature (T{sub L} ≃ 225 K). The second, T{sup *} ∼ 315 ± 5 K, is a special locus of the isothermal compressibility K{sub T}(T, P) and the thermal expansion coefficient α{sub P}(T, P) in the P–T plane. In the case of water confined inside a protein, we observe that these two temperatures mark, respectively, the onset of protein flexibility from its low temperature glass state (T{sub L}) and the onset of the unfolding process (T{sup *})

  19. Culinary art in media

    Directory of Open Access Journals (Sweden)

    Radojičić Dragana

    2009-01-01

    Full Text Available The subject of diet culture is beyond the scope of this paper. Therefore, I concentrated on several examples which best illustrate the presence of culinary art and diet in media. That is, I used 72 articles from the magazine Gloria with the food subject (2006-2009. Diet and culinary arts are omnipresent in media globally. As a rule, many offers recommend recipes and items considered traditional, with a wide range of recipes offered in Serbia alone. Internet also offers many web sites with various diets and recipes. All in all, domestic readers of local journals and magazine can find a variety of fashionable recipes from all over the world, most of the time with limited instructions or groceries not easily obtained at the local market. Bon ton is also lacking while diet and food choices continue to saturate all forms of social behavior as well as recipes serving as communication within a given culture.

  20. Berbudaya Melalui Media Digital

    Directory of Open Access Journals (Sweden)

    Meilani

    2014-10-01

    Full Text Available First of all, to understand and learning the meaning of culture that we know its basic ingredients that form nation culture its a good start. Indonesia known for its diverse culture country from sabang to merauke and off course we Indonesian are proud of it. We should preserve and pass it on to new generation before its gone. Do not let other country claimed our culture teritory for because the lack of nation culture by Indonesian itself. Many ways has been taken to sosialized nation culture in conventional media such as book, magazine and even article. New generation that will inherit Indonesia nation culture nowadays are live in abudance of the world of digital that we called new media. So, it would be so nice if we focus on spreading our nation culture based on what they are interested right now without losing identity of our nation.

  1. Dynamics of Media Attention

    CERN Document Server

    Traag, V A; Hicks, J; van Klinken, G

    2014-01-01

    Studies of human attention dynamics analyses how attention is focused on specific topics, issues or people. In online social media, there are clear signs of exogenous shocks, bursty dynamics, and an exponential or powerlaw lifetime distribution. We here analyse the attention dynamics of traditional media, focussing on co-occurrence of people in newspaper articles. The results are quite different from online social networks and attention. Different regimes seem to be operating at two different time scales. At short time scales we see evidence of bursty dynamics and fast decaying edge lifetimes and attention. This behaviour disappears for longer time scales, and in that regime we find Poissonian dynamics and slower decaying lifetimes. We propose that a cascading Poisson process may take place, with issues arising at a constant rate over a long time scale, and faster dynamics at a shorter time scale.

  2. Trust in media information

    Directory of Open Access Journals (Sweden)

    Miquel Rodrigo

    2003-06-01

    Full Text Available For Miquel Rodrigo, cultural diversity places informative discourse in a crisis because it needs new categories to explain reality, and these categories are not always shared by journalists and by those who receive the information. Instead of gaining an easy trust drawnfrom stereotypes, he proposes, as a better way of overcoming the crisis, fostering the existence of sceptical readers. The media interprets social phenomena with its personal and professional limitations. The sceptical reader is one who knows why the media says what it says and understands that its truths are not absolute, since all ways of seeing are ways of concealing. The relationship between scepticism and trust is that which opposes a blind, acrylic and capitulating trust.

  3. Humanitarian Branding & the Media

    DEFF Research Database (Denmark)

    Vestergaard, Anne

    2006-01-01

    are becoming increasingly commercialized. This paper explores the use of media discourse for the communication of ethical messages by humanitarian organizations, caught, as they are, in a tension between, on the one hand, the commercial strategies of visibility and still greater dependence on the media, and......The development of corporate communication in recent years has brought about a fading of the division of labor between commercial and non-commercial organizations. While the practices of commercial organizations are becoming increasingly ethicalized, so the practices of non-profit organizations......'s branding strategies testify to a high degree of reflexivity about the conditions of what Luc Boltanski calls a Crisis of Pity. The analysis illustrates how, in the face of compassion fatigue, the organization manages to carve out a new space for itself in the marketized ethical discourse, and leads...

  4. Negotiating gender roles through media

    DEFF Research Database (Denmark)

    Gustafsson, Jessica

    The media landscape has changed rapidly in Kenya in the last two decades. Deregulation of the media market has lead to an enormous increase of number of FM stations, and digital TV has opened up for more TV stations. Moreover, TV ownership has increased steadily in last decade and presently mobile....... The interviews deal both with media use and gender and the aim of this paper is to connect the two in order to better grasp how media becomes a platform where gender roles are discussed and negotiated, how media content, whether it is soap operas or call in shows on radio, are used to reflect on one’s own...

  5. Media Makes for Public Learning

    Science.gov (United States)

    Rockman, S.

    2013-12-01

    Learning from media: what studies of media projects can help us understand about informing the public about science issues. Saul Rockman, has studied a variety of television and radio projects funded by NSF, NASA, and foundations. He will highlight findings that inform strategies to increase learning about science content and issues through the media, as well as inform policy on communicating complex scientific ideas to citizens of all ages. Rockman has gathered evidence from science media ranging from Bill Nye The Science Guy to BURN, An Energy Journal.Media for Children vs. Adults

  6. Preliminary study of superconducting bulk magnets for Maglev

    Science.gov (United States)

    Fujimoto, Hiroyuki; Kamijo, Hiroki

    Recent development shows that melt-processed YBaCuO (Y123) or Rare Earth (RE)123 superconductors have a high Jc at 77 K and high magnetic field, leading to high field application as a superconducting quasi-permanent bulk magnet with the liquid nitrogen refrigeration. One of the promising applications is a superconducting magnet for the magnetically levitated (Maglev) train. We discuss a superconducting bulk magnet for the Maglev train in the aspect of a preliminary design of the bulk magnet and also processing for (L)REBaCuO bulk superconductors and their characteristic superconducting properties.

  7. Bulk flow scaling for turbulent channel and pipe flows

    CERN Document Server

    Chen, Xi; She, Zhen-Su

    2016-01-01

    We report a theory deriving bulk flow scaling for canonical wall-bounded flows. The theory accounts for the symmetries of boundary geometry (flat plate channel versus circular pipe) by a variational calculation for a large-scale energy length, which characterizes its bulk flow scaling by a simple exponent, i.e. $m=4$ for channel and 5 for pipe. The predicted mean velocity shows excellent agreement with several dozen sets of quality empirical data for a wide range of the Reynolds number (Re), with a universal bulk flow constant $\\kappa\\approx0.45$. Predictions for dissipation and turbulent transport in the bulk flow are also given, awaiting data verification.

  8. Home media center

    OpenAIRE

    Valverde Martinez, Juan Miguel

    2014-01-01

    One of the most popular indoor entertainment systems nowadays is related to playing multimedia files, not only at home but also in public events such as watching movies in cinemas or playing music in nightclubs or pubs. Developers are responsible for making this easier and innovating in the development of these systems in different ways. This project's goal was to develop a home media center which allows the user to play multimedia files easily. In addition, the development was intended t...

  9. Media in the dump

    OpenAIRE

    Gabrys, Jennifer

    2006-01-01

    'Media in the Dump' examines the phenomenon of electronic waste through five locations, from sites of manufacture (Silicon Valley) to disposal (China). This essay is original in its interdisciplinary approach to the topic of electronic waste. It synthesises fieldwork and scholarship from technology to design and cultural studies. The structure for this essay is original in its surveying of five 'waste ecologies' that traverse the globe.

  10. Michael Faraday, media man.

    Science.gov (United States)

    Fara, Patricia

    2006-03-01

    Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles.

  11. AFLP marker linked to water-stress-tolerant bulks in barley (Hordeum vulgare L.

    Directory of Open Access Journals (Sweden)

    A. Altinkut

    2003-01-01

    Full Text Available The amplified fragment length polymorphism (AFLP assay is an efficient method for the identification of molecular markers, useful in the improvement of numerous crop species. Bulked Segregant Analysis (BSA was used to identify AFLP markers associated with water-stress tolerance in barley, as this would permit rapid selection of water-stress tolerant genotypes in breeding programs. AFLP markers linked to water-stress tolerance was identified in two DNA pools (tolerant and sensitive, which were established using selected F2 individuals resulting from a cross between water-stress-tolerant and sensitive barley parental genotypes, based on their paraquat (PQ tolerance, leaf size, and relative water content (RWC. All these three traits were previously shown to be associated with water-stress tolerance in segregating F2 progeny of the barley cross used in a previous study. AFLP analysis was then performed on these DNA pools, using 40 primer pairs to detect AFLP fragments that are present/absent, respectively, in the two pools and their parental lines. One separate AFLP fragment, which was present in the tolerant parent and in the tolerant bulk, but absent in the sensitive parent and in the sensitive bulk, was identified. Polymorphism of the AFLP marker was tested among tolerant and sensitive F2 individuals. The presence of this marker that is associated with water-stress tolerance will greatly enhance selection for paraquat and water-stress tolerant genotypes in future breeding programs.

  12. 21 CFR 225.158 - Laboratory assays.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Laboratory assays. 225.158 Section 225.158 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... Laboratory assays. Where the results of laboratory assays of drug components, including assays by State...

  13. Heterogeneous recording media

    Science.gov (United States)

    Sukhanov, Vitaly I.

    1991-02-01

    The paper summarizes the results of investigations performed to obtain deep 3-D holograms with 102 i0 mkm physical thickness allowing the postexposure amplification and the a posteriori changing of the grating parameters. This aim has been achieved by developing heterogeneous systems on the basis of porous glass with light-sensitive compositions introduced into it. 1. INTRODUCTION. LIGHT-SENSITIVE MEDIA FOR 3-D HOLOGRAMS RECORDING. The 3-D holograms have many useful properties: very high diffraction efficiency angular and spectral selectivity but low level of noise. It shoud be noted that in this case deep 3-D holograms are dealt with whose physical thickness is as high as 102 -i mkm. Such hologram recording is usually done using homogeneous light-sensitive media for example dyed acid-halide and electrooptical crystals photochrome glass photostructurized polimer compositions and so on. The nature of photophisical and photochemical processes responsible for the light sensitivity of these materials exclude the possibility of post-exposure treatment. This does not allow to enhance the recorded holograms and considerably hampers their fixing or makes it practically impossible. The object of our work is to create the media which are quite suitable for two-stage processes of the deep hologram formation with post-exposure processing. Such material must satisfy the following requirements: a)they must have high permeability for the developing substances in order to make the development duration suitable for practical applications b)they must be shrinkproof to prevent deformation of the

  14. Social Media Marketing

    DEFF Research Database (Denmark)

    Hollensen, Svend; Raman, Anthony

    2014-01-01

    Social media marketing can be understood as a group of Internet-based applications that build on the foundations of Web 2.0 and that then allows the creation and exchange of ‘User Generated Content’. In the ‘Bowling’ marketing world, marketers target certain customer groups and send out...... this is a very direct one-way communication approach. In a social media marketing world, the bowling metaphor does not fit anymore. On this arena marketing can be better described as playing “Pinball”: Companies serve up a “marketing ball” (brands and brand-building messages) into a dynamic and chaotic market...... environment. The “marketing ball” is then diverted and often accelerated by social media “bumpers”, which change the ball’s course in chaotic ways. Occasionally, the marketing ball will come back to the company. At this point, the firm (brand) has to use the flippers to interact and throw it back...

  15. UJI SITOTOKSISITAS BAHAN CYANOACRYLATE VENEER DENGAN MTT ASSAY

    Directory of Open Access Journals (Sweden)

    Elly Munadziroh

    2015-09-01

    Full Text Available The use of acrylic resin restoration basen on methyl methacrylate material in the dentistry, has already been replaced by composite because of certain poor characteristics. Recently, the restoration materials of methyl methacrylate have been re-developed, and made commercially available with cyanoacrylates added. The objective of this study was to investigate the cytotoxic effects of cyanoacrylate veneer materials by 3-(3,4-dimethylthyazol-2yl-2,5-diphenyl retrazolium biomide (MTT assay methods. Cyanoacrylate veneer specimens were immersed in eppendorf microtubes with cell culture media for 1, 12, 24 or 48 hour. Culture media were immersed and used to investigate the cytotoxic effect to BHK 21 cell lines by MTT assay method. The density of optic formazan was live indicate a cell. All data were statistically analyzed by one-way ANOVA and HSD Tukey. The results show that the cytotoxic effects between the five immersion were similar but higher than control cell. In conclusion Immersion in cyanoacrylate veneer has a cytotoxic effect to BHK 21 cell lines. The lowest percentage of cells a live after immersion was 86,95%.

  16. Update on Otitis Media in Children.

    Science.gov (United States)

    Schoem, Scott R.

    1997-01-01

    This article discusses otitis media in children. It addresses risk factors for otitis media, pathogenesis, diagnosis, bacteria causing otitis media, and treatment for acute otitis media, recurrent acute otitis media, and persistent otitis media with effusion, including antibiotics, steroids, allergy control, autoinflation, mechanical ventilation,…

  17. Media Literacy: 21st Century Learning

    Science.gov (United States)

    Baker, Frank W.

    2011-01-01

    The media, for better or worse, deliver the news and the gossip; they entertain, educate and inform. The media have not always been in American classrooms. Yes, teachers teach with media, but rarely do they teach "about" the media. It's called media literacy. Most students are not receiving adequate media literacy instruction, mostly because their…

  18. Novel fermentation media for production of Bacillus thuringiensis subsp. israelensis.

    Science.gov (United States)

    Poopathi, Subbiah; Kumar, K Anup

    2003-08-01

    The production of Bacillus thuringiensis subsp. israelensis (deBarjac) (Bti) as a biopesticide is not cost-effective using existing fermentation technology. In this study, we explored the use of several less expensive alternative culture media (potato, common sugar, and Bengal gram) for the growth and production of Bti. Growth was obtained in all tested media and was comparable to that obtained in conventional medium (Luria-Bertani). Toxicity assays showed that the toxin produced from the novel growth media were effective in killing larvae of Culex quinquefasciatus, Anopheles stephensi, and Aedes aegypti and toxicity was comparable to that produced from Luria-Bertani medium. These observations suggest that potato can be used as a cheap source of culture medium for the production of Bti toxin in mosquito control programs.

  19. Information Provenance in Social Media

    Science.gov (United States)

    Barbier, Geoffrey; Liu, Huan

    Information appearing in social media provides a challenge for determining the provenance of the information. However, the same characteristics that make the social media environment challenging provide unique and untapped opportunities for solving the information provenance problem for social media. Current approaches for tracking provenance information do not scale for social media and consequently there is a gap in provenance methodologies and technologies providing exciting research opportunities for computer scientists and sociologists. This paper introduces a theoretical approach aimed guiding future efforts to realize a provenance capability for social media that is not available today. The guiding vision is the use of social media information itself to realize a useful amount provenance data for information in social media.

  20. Social Media in IS Literature

    DEFF Research Database (Denmark)

    Dyrby, Signe

    2013-01-01

    The phenomenon of ‘digital living’ is to a high extent influenced by the introduction of new media into society. Especially, social media are affecting the digital world of today and are setting the agenda for social connectedness in private, public and commercial networks. Based in an initial...... desire to explore a research agenda for the workings of social media in network structures a look into the literature on social media within the field of Information Systems sparked an interest in exploring a new research perspective for social media. Reviewing the IS literature it is apparent...... that the perspective of the ‘media’ as an artifact of social media has been neglected in existing literature. Based in this, this paper proposes research possibilities for investigating the ‘media’ of social media as well as some theoretical considerations that could aid the investigation. Finally, potential outcomes...

  1. Civic Engagement and Social Media

    DEFF Research Database (Denmark)

    The recent wave of protests, from the Arab Spring to the Occupy movement and austerity protests, have reinvigorated hopes for the democratic potential of the Internet, and particularly social media. With their popular appeal and multimodal affordances social media such as YouTube, Twitter...... and Facebook have generated both media and scholarly interest in their possibilities for granting visibility to and facilitating the organization of activism. However, the role of social media in sustaining civic engagement beyond protest and fatalism remains under-explored. How can social media contribute...... to sustaining longer-term involvement of civil society? What is the potential of social media for making available alternative social imaginaries? And what role may social media play in facilitating social change through cooperation with business? This volume offers answers to these questions by providing...

  2. Media Entrepreneurship: A Consensual Definition

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2017-01-01

    Media Entrepreneurship has been an ambiguous, unclear and controversial concept and despite of growing academic efforts in the last decade, it is still a poorly defined subject. This paper is an effort to fill this gap by providing a comprehensive definition of media entrepreneurship. Firstly......, a literature review conducted and entrepreneurship, media, opportunity and innovation as building blocks of media entrepreneurship explained. Then by using of a mixed of bibliographic method and a Delphi method with multi-stage analysis process, a consensual definition of media entrepreneurship proposed....... This definition integrates some key features of the emerging media environment such as distinction of content and platform, value delivery, opportunity development, non-monetary benefit, etc. It is expected that the findings of this research clear the ground for further researches in the field of media...

  3. Media Literacy in the US

    Directory of Open Access Journals (Sweden)

    Douglas Kellner

    2005-09-01

    Full Text Available Media literacy education is not as advanced in the US as in several other English-speaking areas such as Great Britain, Canada, and Australia. Despite decades of struggle since the 1970s by individuals and groups, media education is still only reaching a small percentage of Americans. While some major inroads have been made, such as getting elements of media literacy included in most of the 50 state's educational standards and the launching of two national media education organizations, most teachers and students in the United States still have never heard of media literacy. In this paper, we first set forth some models of media literacy, delineate key concepts of critical media literacy, and then examine some of the most active organizations in the United States and differences in their goals and pedagogy.

  4. Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry.

    Science.gov (United States)

    Cohen, Joel; Deloid, Glen; Pyrgiotakis, Georgios; Demokritou, Philip

    2013-06-01

    In vitro toxicity assays are efficient and inexpensive tools for screening the increasing number of engineered nanomaterials (ENMs) entering the consumer market. However, the data produced by in vitro studies often vary substantially among different studies and from in vivo data. In part, these discrepancies may be attributable to lack of standardisation in dispersion protocols and inadequate characterisation of particle-media interactions which may affect the particle kinetics and the dose delivered to cells. In this study, a novel approach for preparation of monodisperse, stabilised liquid suspensions is presented and coupled with a numerical model which estimates delivered dose values. Empirically derived material- and media-specific functions are presented for each media-ENM system that can be used to convert administered doses to delivered doses. The interactions of ENMs with a variety of physiologic media were investigated and the importance of this approach was demonstrated by in vitro cytotoxicity assays using THP-1 macrophages.

  5. Bulk Vitrification Castable Refractory Block Protection Study

    Energy Technology Data Exchange (ETDEWEB)

    Hrma, Pavel R.; Bagaasen, Larry M.; Beck, Andrew E.; Brouns, Thomas M.; Caldwell, Dustin D.; Elliott, Michael L.; Matyas, Josef; Minister, Kevin BC; Schweiger, Michael J.; Strachan, Denis M.; Tinsley, Bronnie P.; Hollenberg, Glenn W.

    2005-05-01

    Bulk vitrification (BV) was selected for a pilot-scale test and demonstration facility for supplemental treatment to accelerate the cleanup of low-activity waste (LAW) at the Hanford U.S. DOE Site. During engineering-scale (ES) tests, a small fraction of radioactive Tc (and Re, its nonradioactive surrogate) were transferred out of the LAW glass feed and molten LAW glass, and deposited on the surface and within the pores of the castable refractory block (CRB). Laboratory experiments were undertaken to understand the mechanisms of the transport Tc/Re into the CRB during vitrification and to evaluate various means of CRB protection against the deposition of leachable Tc/Re. The tests used Re as a chemical surrogate for Tc. The tests with the baseline CRB showed that the molten LAW penetrates into CRB pores before it converts to glass, leaving deposits of sulfates and chlorides when the nitrate components decompose. Na2O from the LAW reacts with the CRB to create a durable glass phase that may contain Tc/Re. Limited data from a single CRB sample taken from an ES experiment indicate that, while a fraction of Tc/Re is present in the CRB in a readily leachable form, most of the Tc/Re deposited in the refractory is retained in the form of a durable glass phase. In addition, the molten salts from the LAW, mainly sulfates, chlorides, and nitrates, begin to evaporate from BV feeds at temperatures below 800 C and condense on solid surfaces at temperatures below 530 C. Three approaches aimed at reducing or preventing the deposition of soluble Tc/Re within the CRB were proposed: metal lining, sealing the CRB surface with a glaze, and lining the CRB with ceramic tiles. Metal liners were deemed unsuitable because evaluations showed that they can cause unacceptable distortions of the electric field in the BV system. Sodium silicate and a low-alkali borosilicate glaze were selected for testing. The glazes slowed down molten salt condensate penetration, but did little to reduce the

  6. Active nondestructive assay of nuclear materials: principles and applications

    Energy Technology Data Exchange (ETDEWEB)

    Gozani, Tsahi

    1981-01-01

    The purpose of this book is to present, coherently and comprehensively, the wealth of available but scattered information on the principles and applications of active nondestructive analysis (ANDA). Chapters are devoted to the following: background and overview; interactions of neutrons with matter; interactions of ..gamma..-rays with matter; neutron production and sources; ..gamma..-ray production and sources; effects of neutron and ..gamma..-ray transport in bulk media; signatures of neutron- and photon-induced fissions; neutron and photon detection systems and electronics; representative ANDA systems; and instrument analysis, calibration, and measurement control for ANDA. Each chapter has an introductory section describing the relationship of the topic of that chapter to ANDA. Each chapter ends with a section that summarizes the main results and conclusions of the chapter, and a reference list.

  7. Cavitation instability in bulk metallic glasses

    Directory of Open Access Journals (Sweden)

    Dai L.H.

    2015-01-01

    Full Text Available Recent experiments have shown that fracture surfaces of bulk metallic glasses (BMGs usually exhibit an intriguing nanoscale corrugation like fractographic feature mediated by nanoscale void formation. We attribute the onset of this nanoscale corrugation to TTZs (tension transformation zones mediated cavitation. In our recent study, the spall experiments of Zr-based BMG using a single-stage light gas gun were performed. To uncover the mechanisms of the spallation damage nucleation and evolution, the samples were designed to be subjected to dynamic tensile loadings of identical amplitude but with different durations by making use of the multi-stress pulse and the double-flyer techniques. It is clearly revealed that the macroscopic spall fracture in BMGs originates from the nucleation, growth and coalescence of micro-voids. Then, a microvoid nucleation model of BMGs based on free volume theory is proposed, which indicates that the nucleation of microvoids at the early stage of spallation in BMGs is resulted from diffusion and coalescence of free volume. Furthermore, a theoretical model of void growth in BMGs undergoing remote dynamic hydrostatic tension is developed. The critical condition of cavitation instability is obtained. It is found that dynamic void growth in BMGs can be well controlled by a dimensionless inertial number characterizing the competition between intrinsic and extrinsic time scales. To unveil the atomic-level mechanism of cavitation, a systematic molecular dynamics (MD simulation of spallation behaviour of a binary metallic glass with different impact velocities was performed. It is found that micro-void nucleation is determined TTZs while the growth is controlled by shear transformation zones (STZs at atomic scale.

  8. Silicon bulk micromachined hybrid dimensional artifact.

    Energy Technology Data Exchange (ETDEWEB)

    Claudet, Andre A.; Tran, Hy D.; Bauer, Todd Marks; Shilling, Katherine Meghan; Oliver, Andrew David

    2010-03-01

    A mesoscale dimensional artifact based on silicon bulk micromachining fabrication has been developed and manufactured with the intention of evaluating the artifact both on a high precision coordinate measuring machine (CMM) and video-probe based measuring systems. This hybrid artifact has features that can be located by both a touch probe and a video probe system with a k=2 uncertainty of 0.4 {micro}m, more than twice as good as a glass reference artifact. We also present evidence that this uncertainty could be lowered to as little as 50 nm (k=2). While video-probe based systems are commonly used to inspect mesoscale mechanical components, a video-probe system's certified accuracy is generally much worse than its repeatability. To solve this problem, an artifact has been developed which can be calibrated using a commercially available high-accuracy tactile system and then be used to calibrate typical production vision-based measurement systems. This allows for error mapping to a higher degree of accuracy than is possible with a glass reference artifact. Details of the designed features and manufacturing process of the hybrid dimensional artifact are given and a comparison of the designed features to the measured features of the manufactured artifact is presented and discussed. Measurement results from vision and touch probe systems are compared and evaluated to determine the capability of the manufactured artifact to serve as a calibration tool for video-probe systems. An uncertainty analysis for calibration of the artifact using a CMM is presented.

  9. Biosensor assay for determination of haptoglobin in bovine milk.

    Science.gov (United States)

    Akerstedt, Maria; Björck, Lennart; Persson Waller, Karin; Sternesjö, Ase

    2006-08-01

    Despite more than 30 years of research into mastitis diagnostics, there are few alternatives to the somatic cell count (SCC) in practical use for identification of cows with subclinical mastitis. Mastitis is not only an animal welfare problem, but also affects the yield, composition and technological properties of milk. Hence, dairy cooperatives give farmers a premium quality payment to encourage low SCC although there is no clear scientific data defining the level of SCC in bulk tank milk that is associated with additional benefits in terms of milk quality. Recent research on alternative markers for inflammatory reactions in the lactating cow, e.g. in mastitis, includes investigations of the acute phase protein, haptoglobin (Hp). So far, the content of Hp in milk has mainly been studied in relation to mastitis diagnostics, with little attention given to its importance for milk composition and technological properties. At present, Hp in milk is measured using ELISA, but this technique is not suitable for routine large-scale analysis. In recent years, optical biosensor technology has been used for automated and rapid quantitative analysis of different components in milk, but so far not for analysis of acute phase proteins. The aim of the present study was to develop a rapid and sensitive biosensor method to determine Hp in milk. An affinity sensor assay based on the interaction between Hp and haemoglobin was developed using surface plasmon resonance (SPR) biosensor technology. The assay was used to analyse Hp in composite milk samples from cows without any clinical signs of mastitis and quarter milk samples with a weak to strong reaction in the California Mastitis Test (CMT). A commercial ELISA for determination of Hp in milk was used for comparison. The limit of detection (LOD) of the biosensor assay was determined as 1.1 mg/l. Within-assay and between-day variations were determined both with bulk tank milk spiked with human Hp and with composite milk samples

  10. The skin-blanching assay.

    Science.gov (United States)

    Smit, P; Neumann, H A M; Thio, H B

    2012-10-01

    The skin-blanching assay is used for the determination and bioequivalence of dermatologic glucocorticoids (GCs). The exact mechanism of the production of blanching is not fully understood, but it is considered that local vasoconstriction of the skin microvasculature and the consequent blood-flow reduction cause this phenomenon. Several factors influence skin blanching, including drug concentration, duration of application, nature of vehicle, occlusion, posture and location. The intensity of vasoconstriction can be measured in several ways: visual or quantitative methods, such as reflectance spectroscopy, thermography, laser Doppler velocimetry and chromametry. In literature, contradicting results in the correlation of the skin-blanching assay with different tests to determine GC sensitivity have been reported, limiting its clinical usefulness.

  11. Comet Assay in Cancer Chemoprevention.

    Science.gov (United States)

    Santoro, Raffaela; Ferraiuolo, Maria; Morgano, Gian Paolo; Muti, Paola; Strano, Sabrina

    2016-01-01

    The comet assay can be useful in monitoring DNA damage in single cells caused by exposure to genotoxic agents, such as those causing air, water, and soil pollution (e.g., pesticides, dioxins, electromagnetic fields) and chemo- and radiotherapy in cancer patients, or in the assessment of genoprotective effects of chemopreventive molecules. Therefore, it has particular importance in the fields of pharmacology and toxicology, and in both environmental and human biomonitoring. It allows the detection of single strand breaks as well as double-strand breaks and can be used in both normal and cancer cells. Here we describe the alkali method for comet assay, which allows to detect both single- and double-strand DNA breaks.

  12. Protein binding assay for hyaluronate

    Energy Technology Data Exchange (ETDEWEB)

    Lacy, B.E.; Underhill, C.B.

    1986-11-01

    A relatively quick and simple assay for hyaluronate was developed using the specific binding protein, hyaluronectin. The hyaluronectin was obtained by homogenizing the brains of Sprague-Dawley rats, and then centrifuging the homogenate. The resulting supernatant was used as a source of crude hyaluronectin. In the binding assay, the hyaluronectin was mixed with (/sup 3/H)hyaluronate, followed by an equal volume of saturated (NH/sub 4/)/sub 2/SO/sub 4/, which precipitated the hyaluronectin and any (/sup 3/H)hyaluronate associated with it, but left free (/sup 3/H)hyaluronate in solution. The mixture was then centrifuged, and the amount of bound (/sup 3/H)hyaluronate in the precipitate was determined. Using this assay, the authors found that hyaluronectin specifically bound hyaluronate, since other glycosaminoglycans failed to compete for the binding protein. In addition, the interaction between hyaluronectin and hyaluronate was of relatively high affinity, and the size of the hyaluronate did not appear to substantially alter the amount of binding. To determine the amount of hyaluronate in an unknown sample, they used a competition assay in which the binding of a set amount of (/sup 3/H)hyaluronate was blocked by the addition of unlabeled hyaluronate. By comparing the degree of competition of the unknown samples with that of known amounts of hyaluronate, it was possible to determine the amount of hyaluronate in the unknowns. They have found that this method is sensitive to 1 ..mu..g or less of hyaluronate, and is unaffected by the presence of proteins.

  13. Bioluminescence assay for cell viability.

    Science.gov (United States)

    Lomakina, G Yu; Modestova, Yu A; Ugarova, N N

    2015-06-01

    Theoretical aspects of the adenosine triphosphate bioluminescence assay based on the use of the firefly luciferin-luciferase system are considered, as well as its application for assessing cell viability in microbiology, sanitation, medicine, and ecology. Various approaches for the analysis of individual or mixed cultures of microorganisms are presented, and capabilities of the method for investigation of biological processes in live cells including necrosis, apoptosis, as well as for investigation of the dynamics of metabolism are described.

  14. Environmental Consequences of Nanotechnologies: Nanoparticle Dispersion in Aqueous Media: SOP-T-1

    Science.gov (United States)

    2015-02-01

    ER D C/ EL S R- 15 -2 Environmental Consequences of Nanotechnologies Nanoparticle Dispersion in Aqueous Media: SOP-T-1 En vi ro nm en...dispersions of nanoparticles (NPs) for use in bioassay media for exposures/characterizations are a crucial need in ecotoxicology assays. The present...protocol provides guidance and step-by-step methods for: (1) creating a working stock from nanoparticle powder and nanoparticle aqueous suspensions

  15. Media identities and media-influenced indentifications Visibility and identity recognition in the media

    Directory of Open Access Journals (Sweden)

    Víctor Fco. Sampedro Blanco

    2004-10-01

    Full Text Available The media establish, in large part, the patterns of visibility and public recognition of collective identities. We define media identities as those that are the object of production and diffusion by the media. From this discourse, the communities and individuals elaborate media-influenced identifications; that is, processes of recognition or banishment; (rearticulating the identity markers that the media offer with other cognitive and emotional sources. The generation and appropriation of the identities are subjected to a media hierarchisation that influences their normalisation or marginalisation. The identities presented by the media and assumed by the audience as part of the official, hegemonic discourse are normalised, whereas the identities and identifications formulated in popular and minority terms are marginalised. After presenting this conceptual and analytical framework, this study attempts to outline the logics that condition the presentation, on the one hand, andthe public recognition, on the other hand, of contemporary identities.

  16. Packing Optimization of an Intentionally Stratified Sorbent Bed Containing Dissimilar Media Types

    Science.gov (United States)

    Kidd, Jessica; Guttromson, Jayleen; Holland, Nathan

    2010-01-01

    The Fire Cartridge is a packed bed air filter with two different and separate layers of media designed to provide respiratory protection from combustion products after a fire event on the International Space Station (ISS). The first layer of media is a carbon monoxide catalyst made from gold nanoparticles dispersed on iron oxide. The second layer of media is universal carbon, commonly used in commercial respirator filters. Each layer must be optimally packed to effectively remove contaminants from the air. Optimal packing is achieved by vibratory agitations. However, if post-packing movement of the media within the cartridge occurs, mixing of the bed layers, air voids, and channeling could cause preferential air flow and allow contaminants to pass. Several iterations of prototype fire cartridges were developed to reduce post-packing movement of the media within each layer (settling), and to prevent mixing of the two media types. Both types of movement of the media contribute to decreased fire cartridge performance. Each iteration of the fire cartridge design was tested to demonstrate mechanical loads required to cause detrimental movement within the bed, and resulting level of functionality of the media beds after movement was detected. In order to optimally pack each layer, vertical, horizontal, and orbital agitations were tested and a final packed bulk density was calculated for each method. Packed bulk density must be calculated for each lot of catalyst to accommodate variations in particle size, shape, and density. In addition, a physical divider sheet between each type of media was added within the fire cartridge design to further inhibit intermixing of the bed layers.

  17. Bulk forming of industrial micro components in conventional metals and bulk metallic glasses

    DEFF Research Database (Denmark)

    Arentoft, Mogens; Paldan, Nikolas Aulin; Eriksen, Rasmus Solmer;

    2007-01-01

    For production of micro components in large numbers, forging is an interesting and challenging process. The conventional metals like silver, steel and aluminum often require multi-step processes, but high productivity and increased strength justify the investment. As an alternative, bulk metallic...... glasses will at elevated temperatures behave like a highly viscous liquid, which can easily form even complicated geometries in 1 step. The strengths and limitations of forming the 2 materials are analyzed for a micro 3D component in a silver alloy and an Mg-Cu-Y BMG. ©2007 American Institute of Physics...

  18. Advanced and new developments in bulk metal forming

    DEFF Research Database (Denmark)

    Bay, Niels; Wanheim, Tarras; Ravn, Bjarne Gottlieb;

    2000-01-01

    Increasing demands to manufacturing industry of faster, better and cheaper production has intensified the research and development of bulk metal forming. The present paper gives examples on European industrial research on secondary bulk metal forming processes. The R&D follows three lines of appr...

  19. T-duality trivializes bulk-boundary correspondence

    CERN Document Server

    Mathai, Varghese

    2015-01-01

    Recently we introduced T-duality in the study of topological insulators. In this paper, we study the bulk-boundary correspondence for three phenomena in condensed matter physics, namely, the quantum Hall effect, the Chern insulator, and time reversal invariant topological insulators. In all of these cases, we show that T-duality trivializes the bulk-boundary correspondence.

  20. 7 CFR 58.211 - Packaging room for bulk products.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging room for bulk products. 58.211 Section 58... Service 1 Rooms and Compartments § 58.211 Packaging room for bulk products. A separate room or area shall... dust within the packaging room and where needed, a dust collector shall be provided and...

  1. Import and Export of Bulk Pharmaceuticals in 2006

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ According to customs statistics, the total import and export value of bulk pharmaceuticals (excluding chemical raw materials and bulk pesticides) in China was US$10.346 billion in 2006. The export value was US$7.482 billion - an increase of 22% over the 2005.

  2. 27 CFR 24.301 - Bulk still wine record.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk still wine record. 24..., DEPARTMENT OF THE TREASURY LIQUORS WINE Records and Reports § 24.301 Bulk still wine record. A proprietor who produces or receives still wine in bond, (including wine intended for use as distilling material or...

  3. Nucleation of bulk superconductivity close to critical magnetic fields

    DEFF Research Database (Denmark)

    Fournais, Søren; Kachmar, Ayman

    2011-01-01

    threshold value of the applied magnetic field for which bulk superconductivity contributes to the leading order of the energy. Furthermore, the energy of the bulk is related to that of the Abrikosov problem in a periodic lattice. A key ingredient of the proof is a novel L∞ -bound which is of independent...

  4. Stability of bulk metallic glass structure

    Energy Technology Data Exchange (ETDEWEB)

    Jain, H.; Williams, D.B.

    2003-06-18

    The fundamental origins of the stability of the (Pd-Ni){sub 80}P{sub 20} bulk metallic glasses (BMGs), a prototype for a whole class of BMG formers, were explored. While much of the properties of their BMGs have been characterized, their glass-stability have not been explained in terms of the atomic and electronic structure. The local structure around all three constituent atoms was obtained, in a complementary way, using extended X-ray absorption fine structure (EXAFS), to probe the nearest neighbor environment of the metals, and extended energy loss fine structure (EXELFS), to investigate the environment around P. The occupied electronic structure was investigated using X-ray photoelectron spectroscopy (XPS). The (Pd-Ni){sub 80}P{sub 20} BMGs receive their stability from cumulative, and interrelated, effects of both atomic and electronic origin. The stability of the (Pd-Ni){sub 80}P{sub 20} BMGs can be explained in terms of the stability of Pd{sub 60}Ni{sub 20}P{sub 20} and Pd{sub 30}Ni{sub 50}P{sub 20}, glasses at the end of BMG formation. The atomic structure in these alloys is very similar to those of the binary phosphide crystals near x=0 and x=80, which are trigonal prisms of Pd or Ni atoms surrounding P atoms. Such structures are known to exist in dense, randomly-packed systems. The structure of the best glass former in this series, Pd{sub 40}Ni{sub 40}P{sub 20} is further described by a weighted average of those of Pd{sub 30}Ni{sub 50}P{sub 20} and Pd{sub 60}Ni{sub 20}P{sub 20}. Bonding states present only in the ternary alloys were found and point to a further stabilization of the system through a negative heat of mixing between Pd and Ni atoms. The Nagel and Tauc criterion, correlating a decrease in the density of states at the Fermi level with an increase in the glass stability, was consistent with greater stability of the Pd{sub x}Ni{sub (80-x)}P{sub 20} glasses with respect to the binary alloys of P. A valence electron concentration of 1.8 e/a, which

  5. A Cell Lysis and Protein Purification - Single Molecule Assay Devices for Evaluation of Genetically Engineered Proteins

    Science.gov (United States)

    Nakyama, Tetsuya; Tabata, Kazuhito; Noji, Hiroyuki; Yokokawa, Ryuji

    We have developed two devices applicable to evaluate genetically engineered proteins in single molecule assay: on-chip cell lysis device, and protein purification - assay device. A motor protein, F1-ATPase expressed in E.coli, was focused in this report as a target protein. Cell lysis was simply performed by applying pulse voltage between Au electrodes patterned by photolithography, and its efficiency was determined by absorptiometry. The subsequent processes, purification and assay of extracted proteins, were demonstrated in order to detect F1-ATPase and to evaluate its activity. The specific bonding between his-tag in F1-ATPase and Ni-NTA coated on a glass surface was utilized for the purification process. After immobilization of F1-ATPase, avidin-coated microspheres and adenosine tri-phosphate (ATP) solution were infused sequentially to assay the protein. Microsphere rotation was realized by activity of F1-ATPase corresponding to ATP hydrolysis. Results show that the cell lysis device, at the optimum condition, extracts enough amount of protein for single molecule assay. Once cell lysate was injected to the purification - assay device, proteins were diffused in the lateral direction in a Y-shape microchannel. The gradient of protein concentratioin provides an optimal concentration for the assay i.e. the highest density of rotating beads. Density of rotating beads is also affected by the initial concentration of protein injected to the device. The optimum concentration was achieved by our cell lysis device not by the conventional method by ultrasonic wave. Rotation speed was analyzed for several microspheres assayed in the purification - assay device, and the results were compatible to that of conventional assay in which F1-ATPase was purified in bulk scale. In conclusion, we have demonstrated on-chip cell lysis and assay appropriate for the sequential analysis without any pretreatment. On-chip devices replacing conventional bioanalytical methods will be

  6. Bulk density - RTD results and status of the standardisation

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, T.; Hartmann, H. [Technologie- und Foerderzentrum fuer Nachwachsende Rohstoffe - TFZ, Straubing (Germany); Daugbjerg Jensen, P. [Royal Veterinary and Agricultural University, Vejle (Denmark). Danish Centre for Forest, Landscape and Planning - DFLRI; Temmerman, M.; Rabier, F. [CRA, Gembloux (Belgium). Department Genie Rural; Jirjis, R.; Burvall, J. [Swedish University of Agricultural Sciences, Uppsala (Sweden). Department of Bioenergy; Hersener, J.L. [Ingenieurbuero HERSENER, Wiesendangen (Switzerland); Rathbauer, J. [Bundesanstalt fuer Landtechnik - BLT, Wieselburg (Austria)

    2004-07-01

    Bulk density is an important property for determining storage and transportation room demands and for volume based payment of biofuels. It is also used for calculation of the energy density. Furthermore, bulk density influences the readings from many physical principles for rapid moisture content determination (e. g. microwave reflection method, time domain reflectometric or capacitive sensors [6]). Although bulk density is mostly regarded as an easily determinable parameter, the applied national and international standard methods are highly inconsistent in practice [1, 4, 8]. The goal of the here presented research was therefore to provide a sound knowledge basis for bulk density determination, which shall be used in the ongoing process of European biofuel standardisation. In particular the research focus was to determine the - effect of container size and shape in respect of different biofuels, - effect of shock impact and the - effect of moisture content (as received) on measured bulk density (dry basis). (orig.)

  7. Bulk viscosity, interaction and the viability of phantom solutions

    CERN Document Server

    Leyva, Yoelsy

    2016-01-01

    We study the dynamics of a bulk viscosity model in the Eckart approach for a spatially flat Friedmann-Robertson-Walker (FRW) universe. We have included radiation and dark energy, assumed as perfect fluids, and dark matter treated as an imperfect fluid having bulk viscosity. We also introduce an interaction term between the dark matter and dark energy components. Considering that the bulk viscosity is proportional to the dark matter energy density and imposing a complete cosmological dynamics, we find bounds on the bulk viscosity in order to reproduce a matter-dominated era (MDE). This constraint is independent of the interaction term. Some late time phantom solutions are mathematically possible. However, the constraint imposed by a MDE restricts the interaction parameter, in the phantom solutions, to a region consistent with a null value, eliminating the possibility of late time stable solutions with $w<-1$. From the different cases that we study, the only possible scenario, with bulk viscosity and interac...

  8. Bulk viscosity of spin-one color superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Sa' d, Basil A.

    2009-08-27

    The bulk viscosity of several quark matter phases is calculated. It is found that the effect of color superconductivity is not trivial, it may suppress, or enhance the bulk viscosity depending on the critical temperature and the temperature at which the bulk viscosity is calculated. Also, is it found that the effect of neutrino-emitting Urca processes cannot be neglected in the consideration of the bulk viscosity of strange quark matter. The results for the bulk viscosity of strange quark matter are used to calculate the r-mode instability window of quark stars with several possible phases. It is shown that each possible phase has a different structure for the r-mode instability window. (orig.)

  9. 'Frozen' media subsidies during a time of media change

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis

    2014-01-01

    documents and secondary sources, I show that media subsidies have largely remained frozen in their late-20th century form. The absence of major reform means that media subsidies are increasingly subject to policy drift, a process by which the operations and effectiveness of policies change not because......Media systems around the world have changed in significant ways in the early 21st century. In this article, I analyse how various forms of media subsidies have changed in response to these transformations in a sample of six different affluent democracies. On the basis of interviews, official......) a perceived shortage of desirable, cost-effective, and governable alternatives to existing policies....

  10. Discharge flow of a bidisperse granular media from a silo

    Science.gov (United States)

    Benyamine, M.; Djermane, M.; Dalloz-Dubrujeaud, B.; Aussillous, P.

    2014-09-01

    The discharge flow in a cylindrical and a rectangular silo using both monodisperse and bidisperse mixtures of spherical glass beads is studied experimentally. The flow rate is measured using a precision balance for a large range of particle diameters, size ratios, and outlet diameters. A simple physical model is proposed to describe the flow of bidisperse mixtures. It gives an expression for the flow rate and predicts that the bulk velocity follows a simple mixture law. This model implies that a mixture diameter cannot be simply defined. Moreover it is shown that bidisperse granular media allow for the transport of coarse particles below their jamming conditions.

  11. HITPERM soft magnetic underlayers for perpendicular thin film media

    Science.gov (United States)

    Kumar, S.; Ohkubo, T.; Laughlin, D. E.

    2002-05-01

    In this work, a class of nanocrystalline alloys, HITPERM (Fe, Co)-M-B-Cu (M=Zr, Hf, Nb, and etc.) found to exhibit excellent soft-magnetic properties in bulk were used as soft-magnetic underlayers for perpendicular thin film media. A Ti intermediate layer was used to promote a (00ṡ2) texture and exchange de-couple the magnetic layer (CoCrPt) from the soft-magnetic underlayer. Specimens were deposited at both room and elevated temperature (˜ 250 °C). The results of x-ray diffraction and transmission electron microscope structural studies, along with magnetic properties are presented.

  12. Arginine and glutamine supplementation to culture media improves the performance of various channel catfish immune cells.

    Science.gov (United States)

    Pohlenz, Camilo; Buentello, Alejandro; Mwangi, Waithaka; Gatlin, Delbert M

    2012-05-01

    Specific components of both the innate and adaptive immune systems of channel catfish were evaluated after supplementation of culture media with arginine (ARG) and/or glutamine (GLN). Primary cell cultures of head-kidney macrophages (MØ) were used for phagocytic and bactericidal assays against Edwardsiella ictaluri. Additionally, proliferation assays were conducted with naïve peripheral blood lymphocytes (PBL) exposed to non-specific mitogens. To indirectly assess amino acid utilization of both MØ and PBL, amino acid levels, with emphasis on ARG and GLN, were evaluated in the basal medium before and after activation or mitogenic exposure. After bactericidal and proliferation assays, the sum of the media free amino acid pool significantly (P Glutamine levels in medium decreased by 38% and ARG by 18% during the bactericidal assay. Also, decreases of 52 and 46% from initial values were found after the proliferation assay for GLN and ARG, respectively. Macrophage phagocytosis and killing ability was significantly (P < 0.05) enhanced by ARG supplementation to culture media regardless of GLN supplementation. Proliferation of naïve T- and B-lymphocytes upon mitogenic exposure was significantly (P < 0.05) enhanced by supplementing ARG and GLN to the media, but limited synergistic effects were observed. These results suggest that in vitro, ARG and GLN are important substrates and immunomodulators of both innate and adaptive responses in fish leukocytes, and further highlights the potential use of ARG and GLN as immunonutrients in aquafeeds.

  13. Correlation between the genotoxicity endpoints measured by two different genotoxicity assays: comet assay and CBMN assay

    OpenAIRE

    Carina Ladeira; Susana Viegas; Manuel C. Gomes

    2015-01-01

    The cytokinesis-block micronucleus cytome (CBMN) assay is a comprehensive system for measuring DNA damage; cytostasis and cytotoxicity-DNA damage events are scored specifically in once-divided binucleated cells. The endpoints possible to be measured are micronuclei (MN), a biomarker of chromosome breakage and/or whole chromosome loss, nucleoplasmic bridges (NPB), a biomarker of DNA misrepair and/or telomere end-fusions, and nuclear buds (NBUD), a biomarker of elimination of amplified DNA and/...

  14. Avid Media Composer

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Avid公司的Media Composer电影与视频编辑软件,具有卓越的创造工具、可靠的媒体管理和高质量的效果与输出。Open Timeline(开放性时间线),可帮助用户巧妙处理格式和构思,以及实时编辑和播放多种SD/HD分辨率:P2、XDCAM—HD和HDV格式的原生整合可使用户重点进行编辑;

  15. Crafting digital media

    CERN Document Server

    James, Daniel

    2010-01-01

    Open source software, also known as free software, now offers a creative platform with world-class programs. Just ask the people who have completed high-quality projects or developed popular web 2.0 sites using open source desktop applications. This phenomenon is no longer underground or restricted to techies - there have been more than 61 million downloads of the Audacity audio editor and more than 60 million downloads of the GIMP for Windows photographic tool from SourceForge.net alone. Crafting Digital Media is your foundation course in photographic manipulation, illustration, animation, 3D

  16. Media Bias and Reputation

    OpenAIRE

    Matthew Gentzkow; Jesse M. Shapiro

    2005-01-01

    A Bayesian consumer who is uncertain about the quality of an information source will infer that the source is of higher quality when its reports conform to the consumer's prior expectations. We use this fact to build a model of media bias in which firms slant their reports toward the prior beliefs of their customers in order to build a reputation for quality. Bias emerges in our model even though it can make all market participants worse off. The model predicts that bias will be less severe w...

  17. Towards a Media Architecture

    DEFF Research Database (Denmark)

    Ebsen, Tobias

    2010-01-01

    This text explores the concept of media architecture as a phenomenon of visual culture that describes the use of screen-technology in new spatial configurations in practices of architecture and art. I shall argue that this phenomenon is not necessarily a revolutionary new approach, but rather...... a result of conceptual changes in both modes visual representation and in expressions of architecture. These are changes the may be described as an evolution of ideas and consequent experiments that can be traced back to changes in the history of art and the various styles and ideologies of architecture....

  18. Acoustoelectric effects in reflection of leaky-wave-radiated bulk acoustic waves from piezoelectric crystal-conductive liquid interface.

    Science.gov (United States)

    Rimeika, Romualdas; Čiplys, Daumantas; Jonkus, Vytautas; Shur, Michael

    2016-01-01

    The leaky surface acoustic wave (SAW) propagating along X-axis of Y-cut lithium tantalate crystal strongly radiates energy in the form of an obliquely propagating narrow bulk acoustic wave (BAW) beam. The reflection of this beam from the crystal-liquid interface has been investigated. The test liquids were solutions of potassium nitrate in distilled water and of lithium chloride in isopropyl alcohol with the conductivity varied by changing the solution concentration. The strong dependences of the reflected wave amplitude and phase on the liquid conductivity were observed and explained by the acoustoelectric interaction in the wave reflection region. The novel configuration of an acoustic sensor for liquid media featuring important advantages of separate measuring and sensing surfaces and rigid structure has been proposed. The application of leaky-SAW radiated bulk waves for identification of different brands of mineral water has been demonstrated.

  19. [Eating disorders and mass media].

    Science.gov (United States)

    Peroutsi, A; Gonidakis, F

    2011-01-01

    During the last 50 years, eating disorders have developed to a complicated and widespread medical and social issue. The latest research results indicate that eating disorders have a quite complicated and multifactorial etiology. According to the multifactorial etiological model, the impact of mass media can be regarded mainly as a precipitating factor. The literature review showed that mass media have a considerable impact on the development and perpetuation of eating disorders. Mass media contribute to the promotion of the thinness ideal as a way to achieve social approval, recognition and success. Mass media also promote dieting and food deprivation, as a successful way of life or as a socially agreeable practice. Furthermore, the literature review showed that mass media remain the main source of information about eating disorders. Considering the above result, mass media could play a major role in the promotion of prevention practices and early diagnosis and treatment of eating disorders.

  20. Media Effects: Theory and Research.

    Science.gov (United States)

    Valkenburg, Patti M; Peter, Jochen; Walther, Joseph B

    2016-01-01

    This review analyzes trends and commonalities among prominent theories of media effects. On the basis of exemplary meta-analyses of media effects and bibliometric studies of well-cited theories, we identify and discuss five features of media effects theories as well as their empirical support. Each of these features specifies the conditions under which media may produce effects on certain types of individuals. Our review ends with a discussion of media effects in newer media environments. This includes theories of computer-mediated communication, the development of which appears to share a similar pattern of reformulation from unidirectional, receiver-oriented views, to theories that recognize the transactional nature of communication. We conclude by outlining challenges and promising avenues for future research.

  1. Social media and management fashions

    Directory of Open Access Journals (Sweden)

    Dag Øivind Madsen

    2015-12-01

    Full Text Available The management fashion literature has highlighted the role played by business media (i.e. print media outlets in the diffusion and dissemination of new management concepts and ideas. However, in the last few years, we have witnessed the emergence of social media. Recent research has shown a widespread adoption and usage of social media both in among the general public and professionals in the business community. To date, however, management fashion researchers have not addressed the question of whether social media change the structure and workings of the management fashion market and the ways in which management concepts and ideas are diffused. This article provides a preliminary conceptual elaboration and analysis of how different social media platforms may influence the diffusion and dissemination of fashionable concepts and ideas. The analysis has several implications for research on management fashion.

  2. ELECTRONIC MEDIA AND CHILD BEHAVIOUR

    Directory of Open Access Journals (Sweden)

    Divya Dave

    2011-04-01

    Full Text Available In today’s society, electronic media are thoroughly integrated into the fabric of life, with television, movies, videos, music, video games, and computers, central to both work and play. While these media outlets can provide education and entertainment to children, many researches are concerned with the negative impact electronic media is having on children. Media is used as a third parent or servant. Lot of aspects are important related to media exposure and child behavior. Media exposure affects the neurodevelopment, nutrition and health and academic achievements of the child. Parent education plays an important role in the behavior modification of the children. [National J of Med Res 2011; 1(2.000: 87-89

  3. Social Media as Leisure Culture

    DEFF Research Database (Denmark)

    Albrechtslund, Anne-Mette Bech; Albrechtslund, Anders

    2014-01-01

    The purpose of this paper is to situate the everyday use of social media in the broader cultural practice of leisure. Whereas the use of social media has many different aims and contexts, our main idea is to emphasize how social media practices associated with leisure and playfulness rather than...... functionality and tasks — therefore seemingly “useless” in a strictly utilitarian sense — are practices which are meaningful. We point to certain dynamics in social media practices which we connect to the culture of twentieth century mass tourism, using observations of central touristic practices to motivate...... an analysis of social media use as leisure culture. This gives us a nuanced understanding of the activities connecting everyday life and social media. Further, our analysis provides new insights into the basic motivation for engaging in online sociality despite concerns about privacy, time...

  4. Climate News Across Media Platforms

    DEFF Research Database (Denmark)

    Eskjær, Mikkel Fugl

    2015-01-01

    In a changing media landscape marked by technological, institutional and cultural convergence, comparative and cross-media content analysis represents a valuable analytical tool in mapping the diverse channels of climate change communication. This paper presents a comparative study of climate...... change news on five different media platforms: newspapers, television, radio, web-news and mobile news. It investigates the themes and actors represented in public climate change communication as well as the diverse possibilities of participating in public debates and information sharing. By combining...... quantitative and qualitative content analysis the paper documents and explores the extent and character of climate change news across different media platforms. The study aims at contributing to the on-going assessment of how news media are addressing climate change at a time when old and new media...

  5. Fast methods of computing bulk radiative properties of inhomogeneous clouds illuminated by solar radiation

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, P. [Colorado State Univ., Fort Collins, CO (United States)

    1995-09-01

    The use of cloud fraction as a means of incorporating horizontal cloud inhomogeneity in radiative transfer calculations is widespread in the atmospheric science community. This research attempts to bypass the use of cloud fraction in radiative transfer modeling for two-dimensional media. Gabriel describes two approximation techniques useful in calculating the domain averaged bulk radiative properties such as albedo, flux divergence and mean radiance that dispense with the need to use cloud fraction as a specifier of cloud inhomogeneity. The results suggest that the variability of the medium can largely be accounted for through the pseudo-source term, offering hope of parameterizing the equation of transfer in terms of the statistical properties of the medium. 1 fig.

  6. A Comparison of Kretschmann-Raether Angular Regimes for Measuring Changes in Bulk Refractive Index

    Energy Technology Data Exchange (ETDEWEB)

    KASUNIC, K.J.

    1999-09-16

    We compare 2 angular regimes for the measurement of changes in the real refractive index of bulk fluid analytes. The measurements are based on the use of the Kretschmann-Raether configuration to sense a change in reflectivity with index. Specifically, we numerically simulate the relative sensitivities of the total internal reflection (TIR) and surface-plasmon resonance (SPR) regimes. For a fixed-angle apparatus, the method which gives the greatest change in reflectivity varies with metal film thickness. For films thicker than the skin depth, the SPR regime is the most sensitive to index changes. For thinner films, however, the TIR angle is then dominant, with increases in sensitivity on the order of 75% for 10 nm gold or silver media.

  7. Does social media reduce 'corporate media influence' on journalism?: The Case of Turkish Media

    Directory of Open Access Journals (Sweden)

    Ceren Sozeri

    2011-12-01

    Full Text Available McChesney described one of the biggest problem of journalism as “the journalists have any power to be autonomous from owners and advertisers” (2008:58. Most of media market have been dominated by a few media companies, furthermore a few media conglomerates who had expanded with merger and acquisitions transactions control the biggest part of the global media and entertainment industry. This concentration of media power and penetration of commercial interest in the news media has been seen as affecting the mode of news, profession of journalism and outputs, and consequently, diversity and democracy itself. research aims to examine the potential of social media to create autonomous spaces for journalists working under the commercial pressure of their corporation. In order to analyze this new kind of news area for journalism, three different qualitative methods are used in different steps of research. First, social media utterances of popular journalists were observed to reveal their journalistic intention and they were also evaluated using two case stud- ies about social events which had been tweeted multiple times for many Turkish users (trending topics in Twitter’s agenda. After diversifying the sample, different types of journalists’ social media experiments, including their responsibility to corporations, were examined by qualitative methods including in-depth interviews. Our findings show that although interactions between the journalists and audience observably changed, Twitter, as with other social networks, didn’t diminish the influence of corporate interests on journalism in Turkish media organisations.

  8. Application of the penetration theory for gas - Liquid mass transfer without liquid bulk : Differences with system with a bulk

    NARCIS (Netherlands)

    van Elk, E. P.; Knaap, M. C.; Versteeg, G. F.

    2007-01-01

    Frequently applied micro models for gas-liquid mass transfer all assume the presence of a liquid bulk. However, some systems are characterized by the absence of a liquid bulk, a very thin layer of liquid flows over a solid surface. An example of such a process is absorption in a column equipped with

  9. Hydroponic Growth and the Nondestructive Assay for Dinitrogen Fixation 1

    Science.gov (United States)

    Imsande, John; Ralston, Edward J.

    1981-01-01

    Hydroponic growth medium must be well buffered if it is to support sustained plant growth. Although 1.0 millimolar phosphate is commonly used as a buffer for hydroponic growth media, at that concentration it is generally toxic to a soybean plant that derives its nitrogen solely from dinitrogen fixation. On the other hand, we show that 1.0 to 2.0 millimolar 2-(N-morpholino)ethanesulfonic acid, pKa 6.1, has excellent buffering capacity, and it neither interferes with nor contributes nutritionally to soybean plant growth. Furthermore, it neither impedes nodulation nor the assay of dinitrogen fixation. Hence, soybean plants grown hydroponically on a medium supplemented with 1.0 to 2.0 millimolar 2-(N-morpholino)ethanesulfonic acid and 0.1 millimolar phosphate achieve an excellent rate of growth and, in the absence of added fixed nitrogen, attain a very high rate of dinitrogen fixation. Combining the concept of hydroponic growth and the sensitive acetylene reduction technique, we have devised a simple, rapid, reproducible assay procedure whereby the rate of dinitrogen fixation by individual plants can be measured throughout the lifetime of those plants. The rate of dinitrogen fixation as measured by the nondestructive acetylene reduction procedure is shown to be approximately equal to the rate of total plant nitrogen accumulation as measured by Kjeldahl analysis. Because of the simplicity of the procedure, one investigator can readily assay 50 plants individually per day. PMID:16662112

  10. Alitalia's Crisis in the Media

    DEFF Research Database (Denmark)

    Romenti, Stefania; Valentini, Chiara

    2010-01-01

    Purpose – The purpose of this investigation is to explore Alitalia and the Italian Government’s crisis response strategies (CRSs) implemented in three specific periods of 2008 to understand Alitalia and the Italian Government’s approach in communicating with media stakeholders as well as to exami...... the body of knowledge in crisis communication management and news coverage and offers some suggestions to manage effective media relations within the Italian media system....

  11. Studying Normal, Everyday Social Media

    Directory of Open Access Journals (Sweden)

    Daren C. Brabham

    2015-04-01

    Full Text Available Social media research has tended to focus on stand-out cases and has made use of big data methods to make claims about human experience and sociality. This commentary urges researchers to consider the everyday, normal experiences of most social media users, to consider the place of social media in a broader social context, and to consider marrying big data approaches with interviews and surveys of users.

  12. The Otitis Media-6 questionnaire

    DEFF Research Database (Denmark)

    Heidemann, Christian Hamilton; Godballe, Christian; Kjeldsen, Anette Drøhse;

    2013-01-01

    The Otitis Media-6 questionnaire (OM-6) is the most frequently used instrument to measure health related quality of life in children with otitis media. The main objectives of this study are 1) to translate and cross-culturally adapt the OM-6 into Danish, and 2) to assess important psychometric...... properties including structural validity and interpretability of the OM-6 in a Danish population of children suffering from otitis media....

  13. Anaerobic bacteria in otitis media.

    Science.gov (United States)

    Fulghum, R S; Daniel, H J; Yarborough, J G

    1977-01-01

    Anaerobic bacteria, Peptostrepotococcus intermedius and Propionibacterium acnes, were found in mixed culture specimens from four to ten tested cases of chronic secretory otitis media. These anaerobic bacteria were in a mixed infection flora with aerobic bacteria most often Staphylococcus epidermidis and Cornybacterium sp. which do not fit any established species. The findings of anaerobic bacteria in otitis media is consistent with the sporadic report of the involvement of anaerobic bacteria in otitis media in the literature since 1898.

  14. Multiforms, dyadics, and electromagnetic media

    CERN Document Server

    Lindell, Ismo V

    2015-01-01

    This book applies the four-dimensional formalism with an extended toolbox of operation rules, allowing readers to define more general classes of electromagnetic media and to analyze EM waves that can exist in them. End-of-chapter exercises. Formalism allows readers to find novel classes of media. Covers various properties of electromagnetic media in terms of which they can be set in different classes.

  15. Social Media and the Army

    Science.gov (United States)

    2010-04-01

    Social media has had an undeniable effect on the way we live, work, and communicate throughout the world. Military leaders are recognizing the...importance of social media and taking steps to incorporate change into their organizational cultures. This is partly due to the sheer number of users in the...and watch hundreds of millions of videos. Social media has introduced a whole new language, where complete words now become one letter and smiley faces

  16. Essays in Media and Finance

    OpenAIRE

    2015-01-01

    This Ph.D. thesis consists in three research papers focused on the relationship between media industry and the financial sector. The importance of a correct understanding what is the effect of media on financial markets is becoming increasingly important as long as fully informed markets hypothesis has been challenged. Therefore, if financial markets do not have access to complete information, the importance of information professionals, the media, follows. On the other side, another challeng...

  17. Acute otitis media in children

    Directory of Open Access Journals (Sweden)

    Cherpillod J

    2011-06-01

    Full Text Available Jacques CherpillodEar, Nose and Throat Department, Childrens’ University Hospital, Lausanne, SwitzerlandDate of preparation: 6th March 2011Conflict of interest: None declaredClinical question: What is the best treatment for acute otitis media in children?Results: Watchful waiting, followed by amoxicillin treatment, if necessary, is the best first-line treatment for acute otitis media in children aged six months or older.Keywords: acute otitis media, antibiotics, watchful waitin

  18. Stability Indicating HPLC Determination of Risperidone in Bulk Drug and Pharmaceutical Formulations

    Directory of Open Access Journals (Sweden)

    Zarna R. Dedania

    2011-01-01

    Full Text Available The objective of the current study was to develop a validated stability-indicating assay method (SIAM for risperidone after subjecting it to forced decomposition under hydrolysis, oxidation, photolysis, and thermal stress conditions. The liquid chromatographic separation was achieved isocratically on a symmetry C18 column (5 μm size, 250 mm × 4.6 mm i.d. using a mobile phase containing methanol: acetonitrile (80 : 20, v/v at a flow rate of 1 mL/min and UV detection at 280 nm. Retention time of risperidone was found to be 3.35±0.01. The method was linear over the concentration range of 10–60 μg/mL(2=0.998 with a limit of detection and quantitation of 1.79 and 5.44 μg/mL, respectively. The method has the requisite accuracy, specificity, sensitivity, and precision to assay risperidone in bulk form and pharmaceutical dosage forms. Degradation products resulting from the stress studies did not interfere with the detection of Risperidone, and the assay is thus stability indicating.

  19. In medias res

    DEFF Research Database (Denmark)

    Foote, Jonathan

    2017-01-01

    nor does he begin the Trojan War ab ovo (with the egg) but always he hurries to the action and snatches the listener in medias res (into the middle of things)      Horace, Ars Poetica 145–147 Good epic poets do not commence their tale from the beginning—ab ovo (with the egg)—as Horace states......, but rather descend in medias res (into the middle of things), a reference to the Illiad opening already many years into the Trojan War. Perhaps this sentiment of plunging into the middle of action was felt by researchers in 1976 when, upon the walls of the San Lorenzo New Sacristy in Florence, they uncovered...... sketches, 1:1 scaled architectonic details, and written messages. Among them are the largest drawings known to survive by Michelangelo: two, nearly four meter elevations of the interior and exterior windows of the library, rendered in scale 1:1. Rather than examine the drawings as a history of the building...

  20. Outlooks on Children and Media: Child Rights, Media Trends, Media Research, Media Literacy, Child Participation, Declarations. Children and Media Violence Yearbook, 2001.

    Science.gov (United States)

    von Feilitzen, Cecilia; Bucht, Catharina

    Focusing on media literacy, this yearbook compiles information on recent and current trends in media effects, including research on children and media, declarations related to the area, and a selection of relevant organizations and Web sites. The report first delineates children's rights as stipulated in the U.N. Convention on the Rights of the…