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Sample records for bulk media assay

  1. Bulk media assay using backscattered neutron spectrometry

    International Nuclear Information System (INIS)

    Csikai, J.

    2000-01-01

    This paper summarized a systematic study of bulk media assay using backscattered neutron spectrometry. The source-sample-detector geometry used for the measurements of leakage and elastically backscattered (EBS) spectra of neutrons is shown. Neutrons up to about 14 MeV were produced via 2 H (d,n) and 9 Be (d,n) reactions using different deuteron beam energies between 5 and 10 MeV at the MGC-20E cyclotron of ATOMKI (Debrecen). Neutron yields of the Pu-Be and 252 Cf sources were 5.25 x 10 6 n/s and 1.8 x 10 6 n/s, respectively. Flux density distributions of thermal and primary 14 MeV neutrons were measured for graphite, water and coal samples in various moderator (M)-sample (S)-reflector (R) geometries. Relative fractions and integrated yields of 252 Cf, Pu-Be and 14 MeV neutrons above the (n,n'γ) reaction thresholds for 12 C, 16 O and 28 Si isotopes vs sample thickness have also been determined. It was found that the integrated reaction rate vs sample thickness decreasing exponentially with different attenuation coefficients depending on the neutron spectrum and the composition of the sample. The spectra of neutrons from sources passing through slabs of water, graphite, sand, Al, Fe and Pb up to 20 cm in thickness have been measured by a PHRS system in the 1.2 to 1.5 MeV range. The leakage neutron spectra from a Pu-Be source placed in the center of 30 cm diameter sphere filled with water, paraffin oil, SiO 2 , zeolite and river sand were also measured. The measured spectra have been compared with the calculated results obtained by the three dimensional Monte-Carlo code MCNP-4A and point-wise cross sections from the ENDF/B-4, ENDF/B-6, ENDF/E-1, BROND-2 and JENDL-3.1 data files. New results were obtained for validation of different data libraries from a comparison on the measured and the calculated spectra. Some typical results for water, Al, sand and Fe are shown. A combination of the backscattered neutron spectrometry with the surface gauge used both for the

  2. Collapse of Incoherent Light Beams in Inertial Bulk Kerr Media

    DEFF Research Database (Denmark)

    Bang, Ole; Edmundson, Darran; Królikowski, Wieslaw

    1999-01-01

    We use the coherent density function theory to show that partially coherent beams are unstable and may collapse in inertial bulk Kerr media. The threshold power for collapse, and its dependence on the degree of coherence, is found analytically and checked-numerically. The internal dynamics of the...... of the walk-off modes is illustrated for collapsing and diffracting partially coherent beams.......We use the coherent density function theory to show that partially coherent beams are unstable and may collapse in inertial bulk Kerr media. The threshold power for collapse, and its dependence on the degree of coherence, is found analytically and checked-numerically. The internal dynamics...

  3. Stationary walking solitons in bulk quadratic nonlinear media

    OpenAIRE

    Mihalache, Dumitru; Mazilu, D; Crasonavn, L C; Torner Sabata, Lluís

    1997-01-01

    We study the mutual trapping of fundamental and second-harmonic light beams propagating in bulk quadratic nonlinear media in the presence of Poynting vector beam walk-off. We show numerically the existence of a two-parameter family of (2 + 1)-dimensional stationary, spatial walking solitons. We have found that the solitons exist at various values of material parameters with different wave intensities and soliton velocities. We discuss the differences between (2 + 1) and (1 + 1)-dimensional wa...

  4. Soliton interaction in quadratic and cubic bulk media

    DEFF Research Database (Denmark)

    Johansen, Steffen Kjær; Bang, Ole

    2000-01-01

    Summary form only given. The understanding of how and to what extend the cubic nonlinearity affects beam propagation and spatial soliton formation in quadratic media is of vital importance in fundamental and applied nonlinear physics. We consider beam propagation under type-I SHG conditions...... in lossless bulk second order nonlinear optical materials with a nonvanishing third order nonlinearity. It is known that in pure second order systems a single soliton can never collapse whereas in systems with both nonlinearities and that stable single soliton propagation can only in some circumstances...

  5. Bulk density and aggregate stability assays in percolation columns

    Directory of Open Access Journals (Sweden)

    М. М. Хордан

    2016-12-01

    Full Text Available The restoration technologies in areas degraded by extractive activities require the use of their own mine spoils. Reducing deficiencies in physical properties, organic matter, and nutrients with a contribution of treated sewage sludge is proposed. This experiment was based on a controlled study using columns. The work was done with two mine spoils, both very rich in calcium carbonate. Two sewage sludge doses were undertaken (30,000 and 90,000 kg/ha of sewage sludge in addition to a different mine spoils used as restoration substrates. The water contribution was provided by a device that simulated short duration rain. The leached water was collected 24 hours after the last application. The experiment saw the bulk density decrease and the aggregate stability increase, thereby improving the structure. The improved soil structure decreases its vulnerability to degradation processes such as erosion and compaction.

  6. Bulk media assay using backscattered Pu-Be neutrons

    CERN Document Server

    Csikai, J

    1999-01-01

    Spectral yields of elastically backscattered Pu-Be neutrons measured for graphite, water, polyethylene, liquid nitrogen, paraffin oil, SiO sub 2 , Al, Fe, and Pb slabs show a definite correlation with the energy dependence of the elastic scattering cross sections, sigma sub E sub L (E sub n). The C, N and O can be identified by the different structures in their sigma sub E sub L (E sub n) functions. The integrated spectral yields versus thickness exhibit saturation for each sample. The interrogated volume is limited by the presence of hydrogen in the sample. (author)

  7. Dissociative electron attachment on surfaces and in bulk media

    International Nuclear Information System (INIS)

    Fabrikant, Ilya I.

    2007-01-01

    A theory of dissociative electron attachment to molecules condensed at surfaces and embedded within bulk media is developed. The theory of low-energy electron diffraction is used to obtain the width for electron-molecule resonance scattering in the condensed phase from the width for the gas phase. It is then employed for the calculation of dissociative attachment in the framework of the nonlocal complex potential theory. Specific calculations using the effective mass approximation are carried out for electron attachment to CH 3 Cl and CF 3 Cl molecules physisorbed on the surface of a Kr film. The role of image states and image-potential resonances is analyzed. The results show an increase by several orders of magnitude in the cross section for physisorbed molecules as compared with gas-phase molecules. This is in general agreement with the measured cross sections. However, the position of the peak in the cross section for CH 3 Cl is significantly shifted towards higher energies as compared to experiment [K. Nagesha et al., J. Chem. Phys. 114, 4934 (2001)], and the magnitude of the calculated cross section for CF 3 Cl at the surface is significantly higher than the measured value. Possible reasons for disagreements are analyzed

  8. Direct Assay of Filter Media following DEOX Testing

    International Nuclear Information System (INIS)

    R.P. Lind; J.J. Giglio; D.G. Cummings; M.W. Huntley; C.D. Morgan; K.J. Bateman; D.L. Wahlquist; D.A. Sell

    2007-01-01

    The direct assay of filter media by gamma spectrometry following DEOX testing has distinct advantages over analytical chemistry. Prior to using gamma spectrometry for the quantification of cesium (Cs-137), a calibration must be established with known sources since gamma spectrometry yields relative results. Quantitative analytical chemistry, in particular ICP-MS, has been performed on the filter media for comparison to the gamma spectrometry data. The correlation of gamma spectrometry to ICP-MS data is presented to justify the continued use of gamma spectrometry for filter media

  9. Direct assay of filter media following DEOX testing

    International Nuclear Information System (INIS)

    Westphal, B.R.; Lind, R.P.; Giglio, J.J.; Cummings, D.G.; Huntley, M.W.; Morgan, C.D.; Bateman, K.J.; Wahlquist, D.L.; Sell, D.A.

    2007-01-01

    The direct assay of filter media by gamma spectrometry following DEOX testing has distinct advantages over analytical chemistry. Prior to using gamma spectrometry for the quantification of cesium (Cs- 137), a calibration must be established with known sources since gamma spectrometry yields relative results. Quantitative analytical chemistry, in particular ICP-MS, has been performed on the filter media for comparison to the gamma spectrometry data. The correlation of gamma spectrometry to ICP-MS data is presented to justify the continued use of gamma spectrometry for filter media. (authors)

  10. Efficiency and attenuation correction factors determination in gamma spectrometric assay of bulk samples using self radiation

    International Nuclear Information System (INIS)

    Haddad, Kh.

    2009-02-01

    Gamma spectrometry forms the most important and capable tool for measuring radioactive materials. Determination of the efficiency and attenuation correction factors is the most tedious problem in the gamma spectrometric assay of bulk samples. A new experimental and easy method for these correction factors determination using self radiation was proposed in this work. An experimental study of the correlation between self attenuation correction factor and sample thickness and its practical application was also introduced. The work was performed on NORM and uranyl nitrate bulk sample. The results of proposed methods agreed with those of traditional ones.(author)

  11. Bulk-assay calorimeter: Part 1. System design and operation. Part 2. Calibration and testing

    International Nuclear Information System (INIS)

    Perry, R.B.; Roche, C.T.; Harkness, A.L.; Winslow, G.H.; Youngdahl, G.A.; Lewis, R.N.; Jung, E.A.

    1982-01-01

    The Bulk-Assay Calorimeter is designed to measure the thermal power emitted by plutonium-containing samples. The sample power range of the instrument is 1.4 to 22.4 W. The instrument package consists of the calorimeter measurement chamber, the control circuit power bin, and the data acquisition system. Two sample preheating chambers and five calorimeter canisters for containing the samples are included. A set of 32 test points which monitor voltages at points within the calorimeter and its control circuitry are accessed by the data acquisition system. The use of the test points is described. System start-up and checkout are described. Sample assay and preheater operation procedures are given. The data acquisition system and data analysis software are described. The calorimeter was calibrated at 23 points with heat sources from 1.4 to 22.4 watts. The combined measurement error varied with sample power from 1.4% to 0.1% over the range of calibration measurements. Circuit diagrams for the calorimeter and schematics for the data acquisition system are included

  12. The application of thermoluminescent dosimeters to the measurement of thermal neutron distributions in bulk media

    International Nuclear Information System (INIS)

    Bubb, I.F.; Tang, J.C.N.

    1981-01-01

    The work described was designed to investigate the suitability of measuring neutron flux distributions in bulk media using neutron sensitive thermoluminescent dosimeters, with the initial interest being in wet coal matrices. The phosphors used were 6 LiF and 7 LiF 3.2mmx3.2mmx0.9mm chips. As 7 LiF is sensitive to gamma rays only it was used to correct for the gamma-ray response of 6 LiF

  13. Quantitative comparison of in house irma/ria methods using reagents supplied in bulk with assays based on commercial kits

    International Nuclear Information System (INIS)

    Sajid, K.M.; Jafri, S.R.A.

    1997-01-01

    Due to high cost of commercial kit assays, local trials were started to establish low cost immunoassay techniques at MINAR, Multan. First available alternate of commercial kits was the use of matched reagents supplied in bulk by NETRIA through INMOL, Lahore under IAEA assistance. As quality is crucial in RIA estimations this laboratory collected passive quality control data of 50, 51 and 52 in-house assay batches of T3,T4 and TSH to compare with the same number of last Amerlex RIAs(successive lots). A qualitative comparison based on computerized data analysis shows linear correlation between the results of two assay systems with low and acceptable precision in T3 and T4 assays. In TSH assays both systems show high imprecision although Amerlex RIA system is relatively more precise than in-house TSH- IRMA. T3 and T4 assays in both the systems show wide working ranges covering all clinical regions. In TSH, working ranges of both the techniques do not cover all clinical regions. In-house TSH assay excludes below 5.5 mulU/ml, whereas Amerlex excludes levels below 4.5 mulL/ml. This may reduce the clinical efficacy of these tests. Amerlex-M T3 and T4 assays show high negative drift with relatively less between variation, whereas in-house assays show low positive drift with high between batch variation. (author)

  14. A radiolabel-release microwell assay for proteolytic enzymes present in cell culture media

    International Nuclear Information System (INIS)

    Rucklidge, G.J.; Milne, G.

    1990-01-01

    A modified method for the measurement of proteolytic enzyme activity in cell culture-conditioned media has been developed. Using the release of 3H-labeled peptides from 3H-labeled gelatin the method is performed in microwell plates. The substrate is insolubilized and attached to the wells by glutaraldehyde treatment, thus eliminating the need for a precipitation step at the end of the assay. The assay is sensitive, reproducible, and convenient for small sample volumes. The effect of different protease inhibitors on activity can be assessed rapidly allowing an early characterization of the enzyme. It can also be adapted to microplate spectrophotometric analysis by staining residual substrate with Coomassie blue

  15. Human Sperm Bioassay for Reprotoxicity Testing in Embryo Culture Media: Some Practical Considerations in Reducing the Assay Time

    Directory of Open Access Journals (Sweden)

    Amjad Hossain

    2010-01-01

    Full Text Available Human sperm assay (HSA is a preferred in house quality control and proficiency test (PT practiced in fertility laboratories. HSA is performed over varying durations, apparently without following set criteria. To better understand the assay time required for reprotoxicity testing in embryo culture media, we compared American-Association-of-Bioanalysts-(AAB- administered HSA data to our own assay performed using PT samples obtained from AAB. Participating laboratories were required to culture sperm for 48 hours to determine media acceptability. Conclusions drawn from 48- and 24-hour observations were the same, suggesting that HSA could identify reprotoxic media in less time than required by AAB. Our assay revealed that changes in motility grade in adulterated media are significantly different from those in control media. Furthermore, grade changes can be identified earlier than differences in motility loss between samples. Analyzing motility and motility quality together provides a method for establishing an optimal time for HSA.

  16. Kinetics of β-galactosidase Production by Lactobacillus bulgaricus During pH Controlled Batch Fermentation in Three Commercial Bulk Starter Media

    Directory of Open Access Journals (Sweden)

    Saeed Abbasalizadeh

    2015-10-01

    Full Text Available The potential of bulk starter fermentation strategy for production of a cost-effective and GRAS source of β-galactosidase from a starter culture strain Lactobacillus bulgaricus was investigated. Three different media were selected and the strain, L. bulgaricus DSM 20081 was cultivated in these media under pH-controlled condition (pH = 5.6 at 43°C. The media were: bulk starter medium based on skim milk + whey, bulk starter medium based on whey, and skim milk. Growth and β-lactic acid production parameters were estimated from experimental data with the Garcia and Luedeking-Piret models, respectively. β-galactosidase production kinetics was also simulated using models based on biomass concentration and lactic acid production. Growth in the bulk starter medium based on skim milk + whey resulted in a higher rate of lactic acid production (7.35 ± 0.23  mg lactic acid ml-1 media h-1 and β-galactosidase activity (800.1± 0.7 nmol ONP ml-1 media compared to the other two media (P<0.01. Simulation of β- galactosidase production based on rate of lactic acid production resulted in very good agreement with experimental data for all three tested media. The results revealed the potential of bulk starter fermentation strategy and skim milk + whey based medium for in-house and relatively low cost production of food-grade β-galactosidase by dairy plants.

  17. Numerical Modeling of Anaerobic Microzones Development in Bulk Oxic Porous Media: An Assessment of Different Microzone Formation Processes

    Science.gov (United States)

    Roy Chowdhury, S.; Zarnetske, J. P.; Briggs, M. A.; Day-Lewis, F. D.; Singha, K.

    2017-12-01

    Soil and groundwater research indicates that unique biogeochemical "microzones" commonly form within bulk soil masses. The formation of these microzones at the pore-scale has been attributed to a number of causes, including variability of in situ carbon or nutrient sources, intrinsic physical conditions that lead to dual-porosity and mass transfer conditions, or microbial bioclogging of the porous media. Each of these causes, while documented in different porous media systems, potentially can lead to the presence of anaerobic pores residing in a bulk oxic domain. The relative role of these causes operating independently or in conjunction with each other to form microzones is not known. Here, we use a single numerical modeling framework to assess the relative roles of each process in creating anaerobic microzones. Using a two-dimensional pore-network model, coupled with a microbial growth model based on Monod kinetics, simulations were performed to explore the development of these anoxic microzones and their fate under a range of hydrologic, nutrient, and microbial conditions. Initial results parameterized for a stream-groundwater exchange environment (i.e., a hyporheic zone) indicate that external forcing of fluid flux in the domain is a key soil characteristic to anaerobic microzone development as fluid flux governs the nutrient flux. The initial amount of biomass present in the system also plays a major role in the development of the microzones. In terms of dominant in situ causes, the intrinsic physical structure of the local pore space is found to play the key role in development of anaerobic sites by regulating fluxes to reaction sites. Acknowledging and understanding the drivers of these microzones will improve the ability of multiple disciplines to measure and model reactive mass transport in soils and assess if they play a significant role for particular biogeochemical processes and ecosystem functions, such as denitrification and greenhouse gas production.

  18. Generating Bulk-Scale Ordered Optical Materials Using Shear-Assembly in Viscoelastic Media

    Directory of Open Access Journals (Sweden)

    Chris E. Finlayson

    2017-06-01

    Full Text Available We review recent advances in the generation of photonics materials over large areas and volumes, using the paradigm of shear-induced ordering of composite polymer nanoparticles. The hard-core/soft-shell design of these particles produces quasi-solid “gum-like” media, with a viscoelastic ensemble response to applied shear, in marked contrast to the behavior seen in colloidal and granular systems. Applying an oscillatory shearing method to sub-micron spherical nanoparticles gives elastomeric photonic crystals (or “polymer opals” with intense tunable structural color. The further engineering of this shear-ordering using a controllable “roll-to-roll” process known as Bending Induced Oscillatory Shear (BIOS, together with the interchangeable nature of the base composite particles, opens potentially transformative possibilities for mass manufacture of nano-ordered materials, including advances in optical materials, photonics, and metamaterials/plasmonics.

  19. Comparative study with two different enrichments in the culture media used in the disinfectant efficacy assay.

    Science.gov (United States)

    Sabagh, Bruna Peres; Souto, Aline da Silva Soares; Reis, Louise Moreira; Silva, Sérgio Alves da; Pereira, Daniella Cristina Rodrigues; Neves, Marta de Campos; Pinheiro, Rodrigo Rollin; Duarte, Rafael Silva; Miyazaki, Neide Hiromi Tokumaru; Bôas, Maria Helena Simões Villas

    2012-02-01

    Recent changes in Brazilian legislation for commercial disinfectants have been published due to the recent epidemic of nosocomial infections caused by rapidly growing mycobacteria (RGM) in many states of Brazil over the last 8years. One of these documents requires that all the manufacturers provide evidence of efficacy of sterilizing and disinfectant products, used for semi critical medical devices, against the Mycobacterium bovis BCG Moreau and Mycobacterium abscessus subsp. bolletii INCQS 00594 strains by using the Confirmative in vitro Test for Determining Tuberculocidal Activity of Disinfectants recommended by the Association of Official Analytical Chemists. These changes have caused additional costs and increased problems for importation of enrichment products at national laboratories where disinfectant efficacy assay service is performed. Middlebrook ADC Enrichment (ADC) is provided by a unique manufacturer and used in the official protocol. The aim of the present study was to evaluate an alternative in house low-cost enrichment composed of fetal bovine serum and glucose (FBSG) with ADC for performance of disinfectant efficacy assay against mycobacteria. After obtaining the growth curves for M. abscessus ATCC 19977, M. abscessus subsp. bolletii INCQS 00594, Mycobacterium chelonae ATCC 35752, and Mycobacterium fortuitum ATCC 6841 by using ADC enrichment and FBSG in Kirchners and 7H9 culture media. Through statistical analysis via the Kruskal-Wallis test on the evaluation of microorganism growth rate, it was observed that there was no inhibition of RGM growth by any of the enrichments used. These results suggest that low-cost enrichment FBSG may be used as a potential substitute of ADC for composition of media for mycobacterial growth, including in disinfectant tests. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Comparative study of a novel application of automated HR HPV assay and stability in a previously untested Preservative media.

    Science.gov (United States)

    Morel, Mike E; McBride, Simon E; Gomez, Maria P

    2017-12-01

    The suitability and stability of cervical cells in Novaprep media (NHQ) for certain HPV assays is unknown. We evaluated the accuracy of an automated HPV assay (Abbott RealTime HR HPV) for cervical cells prepared in NHQ and NHQ with a pre-treatment to mimic a worst case clinical use, compared to the assay manufacturers media; repeatability and reproducibility of HPV results and the stability of detectable HPV in NHQ over time compared to CE marked liquid based cytology preservatives. Cell lines were used to simulate patient samples. Cells stored in NHQ produced accurate, repeatable and reproducible results. Stability in NHQ was comparable to the best performing LBC, with at least 7 months' stability at 18-25°C, 2-8°C, -20°C and -80°C; and at least 3 months' stability at 40°C. Similar results were obtained for pre-treated NHQ except only 3.5 months' stability at 18-25°C. Cell line samples in all media and concentrations tested were detected appropriately by the assay. Based on this first stage validation analytical study, cervical cells stored in NHQ are suitable for the Realtime HPV assay. There should be no reservations for inclusion of NHQ in any further validation and clinical performance evaluation of this assay. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  1. Comparative study of a novel application of automated HR HPV assay and stability in a previously untested Preservative media

    Directory of Open Access Journals (Sweden)

    Mike E. Morel

    2017-12-01

    Full Text Available Background: The suitability and stability of cervical cells in Novaprep media (NHQ for certain HPV assays is unknown. Methods: We evaluated the accuracy of an automated HPV assay (Abbott RealTime HR HPV for cervical cells prepared in NHQ and NHQ with a pre-treatment to mimic a worst case clinical use, compared to the assay manufacturers media; repeatability and reproducibility of HPV results and the stability of detectable HPV in NHQ over time compared to CE marked liquid based cytology preservatives. Cell lines were used to simulate patient samples. Results: Cells stored in NHQ produced accurate, repeatable and reproducible results. Stability in NHQ was comparable to the best performing LBC, with at least 7 months’ stability at 18–25 °C, 2–8 °C, −20 °C and −80 °C; and at least 3 months’ stability at 40 °C. Similar results were obtained for pre-treated NHQ except only 3.5 months’ stability at 18–25 °C. Cell line samples in all media and concentrations tested were detected appropriately by the assay. Conclusions: Based on this first stage validation analytical study, cervical cells stored in NHQ are suitable for the Realtime HPV assay. There should be no reservations for inclusion of NHQ in any further validation and clinical performance evaluation of this assay. Keywords: HPV, Preservative, Sample stability, Automated HR HPV assay

  2. Correlation between mastitis occurrence and the count of microorganisms in bulk raw milk of bovine dairy herds in four selective culture media.

    Science.gov (United States)

    Souto, Luís I M; Minagawa, Clarice Y; Telles, Evelise O; Garbuglio, Márcio A; Amaku, Marcos; Melville, Priscilla A; Dias, Ricardo A; Sakata, Sonia T; Benites, Nilson R

    2010-02-01

    Milk is the normal secretion of the mammary gland, practically free of colostrum and obtained by the complete milking of one or more healthy animals. Mastitis is an inflammatory process of the mammary gland and it may cause alterations in the milk. The present work aimed to verify whether it is possible, by means of the counts of microorganism in the bulk raw milk in four selective culture media, to establish a correlation with the occurrence of mastitis and therefore, to monitor this disease in bovine dairy herds. The following selective culture media were used: KF Streptococcus Agar, Edwards Agar, Baird-Parker Agar, Blood Agar plus potassium tellurite. Spearman's correlation coefficient was calculated in order to compare the occurrence of mastitis (percentage) in each herd with respective selective culture media counts of microorganisms in bulk raw milk. Thirty-six possibilities were analysed (Tamis and CMT-positive rates were compared with the log-transformed count in four selective culture media) and there was a negative correlation between Tamis 3 and the Baird-Parker Agar plate count. The total results of microbiological tests showed that there were three correlations of the counts in selective culture media. Fifty-two possibilities were analysed and there was a negative correlation between no-bacterial-growth mastitis rates and log10 of KF Streptoccocus Agar plate count and there were two positive correlations between coagulase-positive staphylococci and log10 of Baird-Parker Agar plate count and Blood Agar plus potassium tellurite plate count.

  3. An Approach for Assessing the Signature Quality of Various Chemical Assays when Predicting the Culture Media Used to Grow Microorganisms

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, Aimee E.; Sego, Landon H.; Webb-Robertson, Bobbie-Jo M.; Kreuzer, Helen W.; Anderson, Richard M.; Unwin, Stephen D.; Weimar, Mark R.; Tardiff, Mark F.; Corley, Courtney D.

    2013-02-01

    We demonstrate an approach for assessing the quality of a signature system designed to predict the culture medium used to grow a microorganism. The system was comprised of four chemical assays designed to identify various ingredients that could be used to produce the culture medium. The analytical measurements resulting from any combination of these four assays can be used in a Bayesian network to predict the probabilities that the microorganism was grown using one of eleven culture media. We evaluated combinations of the signature system by removing one or more of the assays from the Bayes network. We measured and compared the quality of the various Bayes nets in terms of fidelity, cost, risk, and utility, a method we refer to as Signature Quality Metrics

  4. "From safe source to safe sink" development of colorimetric assay for gabapentin in bulk drug and capsules using naturally derived genipin.

    Science.gov (United States)

    Winotapun, Weerapath; Kongpakwattana, Khachen; Dejpittayanunt, Sirirat; Pathomcharoensukchai, Suwaparp; Suksaran, Udomluck; Nuntharatanapong, Nopparat; Rojanarata, Theerasak

    2012-09-15

    A novel colorimetric assay for gabapentin in bulk drug and capsules has been developed via a safety-and-sustainability concerning concept. The method relied on the reaction of primary amino group of drug with non-toxic and eco-friendly genipin in totally aqueous medium to form the blue product which was subsequently measured by visible spectrophotometry at 590 nm. Under the optimized conditions, Beer's law was obeyed in the concentration range of 0.15-0.50 mM (r(2)=0.9998). It was accurate, precise and insensitive to the interferences from all related compounds specified in the United States Pharmacopeia as well as commonly used excipients. Furthermore, it gave the assay results in agreement with the pharmacopeial chromatographic method. Owing to the environmental concern and responsibility, a fast and facile method was also proposed for the treatment of waste generated from the assay based on the decoloration by using gypsum as a cheap and commonly available adsorbent. After the treatment, more than 95% of the initial blue product was removed from the waste solution and the treated waste was proven to be safe for aquatic organisms, as studied in brine shrimp and guppy fishes. Therefore, this work not only reports for the first time the application of naturally derived genipin to drug analysis, but also presents a new and contemporary paradigm that illustrates the fully benign-by-design development of the analytical methodologies in the era of Green Chemistry, starting from the safe source of reagents toward the safe sink when waste is released into the environment. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Optimization of Forced Degradation Using Experimental Design and Development of a Stability-Indicating Liquid Chromatographic Assay Method for Rebamipide in Bulk and Tablet Dosage Form

    Directory of Open Access Journals (Sweden)

    Sandeep SONAWANE

    2016-09-01

    Full Text Available A novel stability-indicating RP-HPLC assay method was developed and validated for quantitative determination of rebamipide in bulk and tablet dosage form. Rebamipide (drug and drug product solutions were exposed to acid and alkali hydrolysis, thermal stress, oxidation by hydrogen peroxide and photodegradation. Experimental design has been used during forced degradation to determine significant factors responsible for degradation and to obtain optimal degradation conditions. In addition, acid and alkali hydrolysis was performed using a microwave oven. The chromatographic method employed the HiQ sil C-18HS (250 × 4.6 mm; 5 μm column with mobile phase consisting of 0.02 M potassium phosphate (pH adjusted to 6.8 and methanol (40:60, v/v and the detection was performed at 230 nm. The procedure was validated for specificity, linearity, accuracy, precision and robustness. There was no interference observed of excipients and degradation products in the determination of the active pharmaceutical ingredient. The method showed good accuracy and precision (intra and inter day and the response was linear in a range from 0.5 to 5 μg mL−1. The method was found to be simple and fast with less trial and error experimentation by making use of experimental design. Also, it proved that microwave energy can be used to expedite hydrolysis of rebamipide.

  6. Initial cytotoxicity assays of media for sulfate-reducing bacteria: An endodontic biopharmaceutical product under development.

    Science.gov (United States)

    Heggendorn, Fabiano Luiz; Silva, Gabriela Cristina de Carvalho; Cardoso, Elisama Azevedo; Castro, Helena Carla; Gonçalves, Lúcio Souza; Dias, Eliane Pedra; Lione, Viviane de Oliveira Freitas; Lutterbach, Márcia Teresa Soares

    2016-01-01

    This study assessed the cell viability of the inoculation vehicle of BACCOR (a combination of sulfate-reducing bacteria plus a culture media for bacteria), a biopharmaceutical product under development for dental use as aid in fractured endodontic file removal from the root canal. Different culture media for bacteria were evaluated: modified Postgate E (MCP-E mod), Modified Postgate E without Agar-agar (MCP-E w/Ag), Postgate C with Agar-agar (MCP-C Ag) and Postgate C without Agar-agar (MCP-C w/Ag). Cytotoxicity was quantified by the MTT test, exposing L929 and Vero cell lines to the vehicles over 24 h. The exposure of L929 cell line to MCP-E w/Ag resulted in biocompatibility (52% cell viability), while the exposure of the Vero kidney line revealed only MCP-E mod as cytotoxic. When diluted, all the vehicles showed biocompatibility with both cell lines. MCP-E w/Ag was the vehicle chosen for BACCOR, because of its biocompatibility with the cells used.

  7. Spectrophotometric assay of pioglitazone hydrochloride using permanganate in acidic and basic media

    Directory of Open Access Journals (Sweden)

    Kanakapura Basavaiah

    2018-04-01

    Full Text Available Pioglitazone hydrochloride (PGH is an oral anti-hyperglycemic agent used in the treatment of type-2 diabetes mellitus. Potassium permanganate was found to oxidize PGH both in acidic and basic conditions, based on which two simple and sensitive methods were developed for its determination in bulk sample and tablets, and validated. In the first method (indirect method, PGH was reacted with a measured excess of standard permanganate in H2SO4 medium, and the residual oxidant was determined by measuring its absorbance at 550 nm. The second method (Direct method entails treating PGH with permanganate in NaOH medium, followed by the measurement of the resulting bluish-green manganite at 610 nm. Experimental variables affecting the reactions were studied and optimized. Under optimum conditions, linear relationships with good correlation coefficients were found between absorbance and concentration in the ranges, 1.25 – 25 µg mL-1 (Indirect method and 1-12 µg mL-1 (Direct method with respective molar absorptivity values of 1.10 × 104 and 2.77 × 104 l mol-1 cm-1. The limits of detection (LOD and quantification (LOQ were 0.36 and 1.08 (Indirect method and 0.23 and 0.69 µg mL-1 (Direct method. Intra-day and inter-day precisions were satisfactory, with %RSD values of ≤2.11, and the respective accuracies were excellent with %RE values of ≤2. The methods were also validated for robustness, ruggedness and selectivity. The methods were applied to the determination of PGH in its tablets with good accuracy and precision, and no interference from the tablet additives was encountered. The results were also compared with those obtained by a reference method.

  8. Bulk derivatization and cation exchange restricted access media-based trap-and-elute liquid chromatography–mass spectrometry method for determination of trace estrogens in serum

    International Nuclear Information System (INIS)

    Beinhauer, Jana; Bian, Liangqiao; Fan, Hui; Šebela, Marek; Kukula, Maciej; Barrera, Jose A.

    2015-01-01

    Highlights: • Analysis of estrogens in small volume samples at low parts-per-trillion concentration. • Charged bulk derivatization facilitates on-line ion exchange sample preparation. • On-line WCX restricted access media traps analytes, but not proteins and lipids. • Complete preparation and LC–MS/MS analysis completed in 30 min/sample. - Abstract: Estrone (E1), estradiols (α/β-E2), and estriol (E3) are four major metabolically active estrogens exerting strong biological activities at very low circulating concentrations. This paper reports a sensitive and efficient method with automated, on-line clean-up and detection to determine trace estrogens in a small volume of serum samples using liquid chromatography–electrospray ionization–tandem mass spectrometry directly, without off-line liquid–liquid or solid-phase extraction pretreatments. Serum aliquots (charcoal stripped fetal bovine serum, 100 μL) were spiked with four estrogen standards and their corresponding isotope-labeled internal standards, then bulk derivatized with 2-fluoro-1-methyl-pyridium p-toluenesulfonate (2-FMP) to establish the calibration curves and perform method validation. Calibration was established in the concentration ranges of 5–1000 pg mL −1 , and demonstrated good linearity of R 2 from 0.9944 to 0.9997 for the four derivatized estrogens. The lower detection limits obtained were 3–7 pg mL −1 . Good accuracy and precision in the range of 86–112% and 2.3–11.9%, respectively, were observed for the quality control (QC) samples at low, medium, and high concentration levels. The stability tests showed that the derivatized serum samples were stable 8 h after derivatization at room temperature and at least to 48 h if stored at −20 °C. The method was applied to measure trace estrogens in real human and bovine serum samples, and three of four estrogen compounds studied were observed and quantified

  9. Diagnostic performance of an indirect enzyme-linked immunosorbent assay (ELISA) to detect bovine leukemia virus antibodies in bulk-tank milk samples

    Science.gov (United States)

    Nekouei, Omid; Durocher, Jean; Keefe, Greg

    2016-01-01

    This study assessed the diagnostic performance of a commercial ELISA for detecting bovine leukemia virus antibodies in bulk-tank milk samples from eastern Canada. Sensitivity and specificity of the test were estimated at 97.2% and 100%, respectively. The test was recommended as a cost-efficient tool for large-scale screening programs. PMID:27429469

  10. Bulk derivatization and cation exchange restricted access media-based trap-and-elute liquid chromatography–mass spectrometry method for determination of trace estrogens in serum

    Energy Technology Data Exchange (ETDEWEB)

    Beinhauer, Jana [Department of Biochemistry, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Centre of the Region Haná for Biotechnological and Agricultural Research - Department of Protein Biochemistry and Proteomics, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Bian, Liangqiao [Shimadzu Center for Advanced Analytical Chemistry, The University of Texas at Arlington, Arlington, TX (United States); Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); Fan, Hui [Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, TX (United States); Šebela, Marek [Department of Biochemistry, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Centre of the Region Haná for Biotechnological and Agricultural Research - Department of Protein Biochemistry and Proteomics, Faculty of Science, Palacký University, Šlechtitelů 11, CZ-783 71 Olomouc (Czech Republic); Kukula, Maciej [Shimadzu Center for Advanced Analytical Chemistry, The University of Texas at Arlington, Arlington, TX (United States); Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); Barrera, Jose A. [Shimadzu Institute for Research Technologies, The University of Texas at Arlington, Arlington, TX (United States); and others

    2015-02-09

    Highlights: • Analysis of estrogens in small volume samples at low parts-per-trillion concentration. • Charged bulk derivatization facilitates on-line ion exchange sample preparation. • On-line WCX restricted access media traps analytes, but not proteins and lipids. • Complete preparation and LC–MS/MS analysis completed in 30 min/sample. - Abstract: Estrone (E1), estradiols (α/β-E2), and estriol (E3) are four major metabolically active estrogens exerting strong biological activities at very low circulating concentrations. This paper reports a sensitive and efficient method with automated, on-line clean-up and detection to determine trace estrogens in a small volume of serum samples using liquid chromatography–electrospray ionization–tandem mass spectrometry directly, without off-line liquid–liquid or solid-phase extraction pretreatments. Serum aliquots (charcoal stripped fetal bovine serum, 100 μL) were spiked with four estrogen standards and their corresponding isotope-labeled internal standards, then bulk derivatized with 2-fluoro-1-methyl-pyridium p-toluenesulfonate (2-FMP) to establish the calibration curves and perform method validation. Calibration was established in the concentration ranges of 5–1000 pg mL{sup −1}, and demonstrated good linearity of R{sup 2} from 0.9944 to 0.9997 for the four derivatized estrogens. The lower detection limits obtained were 3–7 pg mL{sup −1}. Good accuracy and precision in the range of 86–112% and 2.3–11.9%, respectively, were observed for the quality control (QC) samples at low, medium, and high concentration levels. The stability tests showed that the derivatized serum samples were stable 8 h after derivatization at room temperature and at least to 48 h if stored at −20 °C. The method was applied to measure trace estrogens in real human and bovine serum samples, and three of four estrogen compounds studied were observed and quantified.

  11. Challenges for bovine viral diarrhoea virus antibody detection in bulk milk by antibody enzyme-linked immunosorbent assays due to changes in milk production levels

    DEFF Research Database (Denmark)

    Foddai, Alessandro; Enøe, Claes; Stockmarr, Anders

    2015-01-01

    Background: Bovine viral diarrhoea (BVD) is considered eradicated from Denmark. Currently, very few (if any) Danish cattle herds could be infected with BVD virus (BVDV). The Danish antibody blocking enzyme-linked immunosorbent assay (ELISA) has been successfully used during the Danish BVD eradica...

  12. Instrumentation and procedures for moisture corrections to passive neutron coincidence counting assays of bulk PuO2 and MOX powders

    International Nuclear Information System (INIS)

    Stewart, J.E.; Menlove, H.O.; Ferran, R.R.; Aparo, M.; Zeppa, P.; Troiani, F.

    1993-05-01

    For passive neutron-coincidence-counting verification measurements of PuO 2 and MOX powder, assay biases have been observed that result from moisture entrained in the sample. This report describes a unique set of experiments in which MOX samples, with a range of moisture concentrations, were produced and used to calibrate and evaluate two prototype moisture monitors. A new procedure for moisture corrections to PuO 2 and MOX verification measurements yields MOX assays accurate to 1.5% (1σ) for 0.6- and 1.1-kg samples. Monte Carlo simulations were used to extend the measured moisture calibration data to higher sample masses. A conceptual design for a high-efficiency neutron coincidence counter with improved sensitivity to moisture is also presented

  13. MicrO: an ontology of phenotypic and metabolic characters, assays, and culture media found in prokaryotic taxonomic descriptions.

    Science.gov (United States)

    Blank, Carrine E; Cui, Hong; Moore, Lisa R; Walls, Ramona L

    2016-01-01

    MicrO is an ontology of microbiological terms, including prokaryotic qualities and processes, material entities (such as cell components), chemical entities (such as microbiological culture media and medium ingredients), and assays. The ontology was built to support the ongoing development of a natural language processing algorithm, MicroPIE (or, Microbial Phenomics Information Extractor). During the MicroPIE design process, we realized there was a need for a prokaryotic ontology which would capture the evolutionary diversity of phenotypes and metabolic processes across the tree of life, capture the diversity of synonyms and information contained in the taxonomic literature, and relate microbiological entities and processes to terms in a large number of other ontologies, most particularly the Gene Ontology (GO), the Phenotypic Quality Ontology (PATO), and the Chemical Entities of Biological Interest (ChEBI). We thus constructed MicrO to be rich in logical axioms and synonyms gathered from the taxonomic literature. MicrO currently has ~14550 classes (~2550 of which are new, the remainder being microbiologically-relevant classes imported from other ontologies), connected by ~24,130 logical axioms (5,446 of which are new), and is available at (http://purl.obolibrary.org/obo/MicrO.owl) and on the project website at https://github.com/carrineblank/MicrO. MicrO has been integrated into the OBO Foundry Library (http://www.obofoundry.org/ontology/micro.html), so that other ontologies can borrow and re-use classes. Term requests and user feedback can be made using MicrO's Issue Tracker in GitHub. We designed MicrO such that it can support the ongoing and future development of algorithms that can leverage the controlled vocabulary and logical inference power provided by the ontology. By connecting microbial classes with large numbers of chemical entities, material entities, biological processes, molecular functions, and qualities using a dense array of logical axioms, we

  14. A Simple and Specific Stability- Indicating RP-HPLC Method for Routine Assay of Adefovir Dipivoxil in Bulk and Tablet Dosage Form.

    Science.gov (United States)

    Darsazan, Bahar; Shafaati, Alireza; Mortazavi, Seyed Alireza; Zarghi, Afshin

    2017-01-01

    A simple and reliable stability-indicating RP-HPLC method was developed and validated for analysis of adefovir dipivoxil (ADV).The chromatographic separation was performed on a C 18 column using a mixture of acetonitrile-citrate buffer (10 mM at pH 5.2) 36:64 (%v/v) as mobile phase, at a flow rate of 1.5 mL/min. Detection was carried out at 260 nm and a sharp peak was obtained for ADV at a retention time of 5.8 ± 0.01 min. No interferences were observed from its stress degradation products. The method was validated according to the international guidelines. Linear regression analysis of data for the calibration plot showed a linear relationship between peak area and concentration over the range of 0.5-16 μg/mL; the regression coefficient was 0.9999and the linear regression equation was y = 24844x-2941.3. The detection (LOD) and quantification (LOQ) limits were 0.12 and 0.35 μg/mL, respectively. The results proved the method was fast (analysis time less than 7 min), precise, reproducible, and accurate for analysis of ADV over a wide range of concentration. The proposed specific method was used for routine quantification of ADV in pharmaceutical bulk and a tablet dosage form.

  15. Potentiodynamic polarization studies of bulk amorphous alloy Zr57Cu15.4Ni12.6Al10Nb5 and Zr59Cu20Ni8Al10Ti3 in aqueous HNO3 media

    International Nuclear Information System (INIS)

    Sharma, Poonam; Dhawan, Anil; Jayraj, J.; Kamachi Mudali, U.

    2013-01-01

    The potentiodynamic polarization studies were carried out on Zr based bulk amorphous alloy Zr 57 Cu 15.4 Ni 12.6 Al 10 Nb 5 and Zr 59 Cu 20 Ni 8 Al 10 Ti 3 in solutions of 1 M, 6 M and 11.5 M HNO 3 aqueous media at room temperature. As received specimens of Zr 57 Cu 15.4 Ni 12.6 Al 10 Nb 5 (5 mm diameter rod) and Zr 59 Cu 20 Ni 8 Al 10 Ti 3 (3 mm diameter rod) were polished with SiC paper before testing them for potentiodynamic polarization studies. The amorphous nature of the specimens was checked by X-ray diffraction. The bulk amorphous alloy Zr 59 Cu 20 Ni 8 Al 10 Ti 3 shows the better corrosion resistance than Zr 57 Cu 15.4 Ni 12.6 Al 10 Nb 5 alloy in the aqueous HNO 3 media as the value of the corrosion current density (I corr ) for Zr 57 Cu 15.4 Ni 12.6 Al 10 Nb 5 alloy were found to be more than Zr 59 Cu 20 Ni 8 Al 10 Ti 3 alloy in aqueous HNO 3 media. The improved corrosion resistance of Zr 59 Cu 20 Ni 8 Al 10 Ti 3 alloy is possibly due to the presence of Ti and formation of TiO 2 during anodic oxidation. Both Zr based bulk amorphous alloys shows wider passive range at lower concentration of nitric acid and the passive region gets narrowed down with the increase in concentration. A comparison of data obtained from both the Zr-based bulk amorphous alloys is made and results are discussed in the paper. (author)

  16. Permeability to macromolecular contrast media quantified by dynamic MRI correlates with tumor tissue assays of vascular endothelial growth factor (VEGF)

    International Nuclear Information System (INIS)

    Cyran, Clemens C.; Sennino, Barbara; Fu, Yanjun; Rogut, Victor; Shames, David M.; Chaopathomkul, Bundit; Wendland, Michael F.; McDonald, Donald M.; Brasch, Robert C.; Raatschen, Hans-Juergen

    2012-01-01

    Purpose: To correlate dynamic MRI assays of macromolecular endothelial permeability with microscopic area–density measurements of vascular endothelial growth factor (VEGF) in tumors. Methods and material: This study compared tumor xenografts from two different human cancer cell lines, MDA-MB-231 tumors (n = 5), and MDA-MB-435 (n = 8), reported to express respectively higher and lower levels of VEGF. Dynamic MRI was enhanced by a prototype macromolecular contrast medium (MMCM), albumin-(Gd-DTPA)35. Quantitative estimates of tumor microvascular permeability (K PS ; μl/min × 100 cm 3 ), obtained using a two-compartment kinetic model, were correlated with immunohistochemical measurements of VEGF in each tumor. Results: Mean K PS was 2.4 times greater in MDA-MB-231 tumors (K PS = 58 ± 30.9 μl/min × 100 cm 3 ) than in MDA-MB-435 tumors (K PS = 24 ± 8.4 μl/min × 100 cm 3 ) (p < 0.05). Correspondingly, the area–density of VEGF in MDA-MB-231 tumors was 2.6 times greater (27.3 ± 2.2%, p < 0.05) than in MDA-MB-435 cancers (10.5 ± 0.5%, p < 0.05). Considering all tumors without regard to cell type, a significant positive correlation (r = 0.67, p < 0.05) was observed between MRI-estimated endothelial permeability and VEGF immunoreactivity. Conclusion: Correlation of MRI assays of endothelial permeability to a MMCM and VEGF immunoreactivity of tumors support the hypothesis that VEGF is a major contributor to increased macromolecular permeability in cancers. When applied clinically, the MMCM-enhanced MRI approach could help to optimize the appropriate application of VEGF-inhibiting therapy on an individual patient basis.

  17. Laboratory Performance of Five Selected Soil Moisture Sensors Applying Factory and Own Calibration Equations for Two Soil Media of Different Bulk Density and Salinity Levels

    Science.gov (United States)

    Matula, Svatopluk; Báťková, Kamila; Legese, Wossenu Lemma

    2016-01-01

    Non-destructive soil water content determination is a fundamental component for many agricultural and environmental applications. The accuracy and costs of the sensors define the measurement scheme and the ability to fit the natural heterogeneous conditions. The aim of this study was to evaluate five commercially available and relatively cheap sensors usually grouped with impedance and FDR sensors. ThetaProbe ML2x (impedance) and ECH2O EC-10, ECH2O EC-20, ECH2O EC-5, and ECH2O TE (all FDR) were tested on silica sand and loess of defined characteristics under controlled laboratory conditions. The calibrations were carried out in nine consecutive soil water contents from dry to saturated conditions (pure water and saline water). The gravimetric method was used as a reference method for the statistical evaluation (ANOVA with significance level 0.05). Generally, the results showed that our own calibrations led to more accurate soil moisture estimates. Variance component analysis arranged the factors contributing to the total variation as follows: calibration (contributed 42%), sensor type (contributed 29%), material (contributed 18%), and dry bulk density (contributed 11%). All the tested sensors performed very well within the whole range of water content, especially the sensors ECH2O EC-5 and ECH2O TE, which also performed surprisingly well in saline conditions. PMID:27854263

  18. Carbon nanotubes grown on bulk materials and methods for fabrication

    Science.gov (United States)

    Menchhofer, Paul A [Clinton, TN; Montgomery, Frederick C [Oak Ridge, TN; Baker, Frederick S [Oak Ridge, TN

    2011-11-08

    Disclosed are structures formed as bulk support media having carbon nanotubes formed therewith. The bulk support media may comprise fibers or particles and the fibers or particles may be formed from such materials as quartz, carbon, or activated carbon. Metal catalyst species are formed adjacent the surfaces of the bulk support material, and carbon nanotubes are grown adjacent the surfaces of the metal catalyst species. Methods employ metal salt solutions that may comprise iron salts such as iron chloride, aluminum salts such as aluminum chloride, or nickel salts such as nickel chloride. Carbon nanotubes may be separated from the carbon-based bulk support media and the metal catalyst species by using concentrated acids to oxidize the carbon-based bulk support media and the metal catalyst species.

  19. Bulk oil clauses

    International Nuclear Information System (INIS)

    Gough, N.

    1993-01-01

    The Institute Bulk Oil Clauses produced by the London market and the American SP-13c Clauses are examined in detail in this article. The duration and perils covered are discussed, and exclusions, adjustment clause 15 of the Institute Bulk Oil Clauses, Institute War Clauses (Cargo), and Institute Strikes Clauses (Bulk Oil) are outlined. (UK)

  20. Large area bulk superconductors

    Science.gov (United States)

    Miller, Dean J.; Field, Michael B.

    2002-01-01

    A bulk superconductor having a thickness of not less than about 100 microns is carried by a polycrystalline textured substrate having misorientation angles at the surface thereof not greater than about 15.degree.; the bulk superconductor may have a thickness of not less than about 100 microns and a surface area of not less than about 50 cm.sup.2. The textured substrate may have a thickness not less than about 10 microns and misorientation angles at the surface thereof not greater than about 15.degree.. Also disclosed is a process of manufacturing the bulk superconductor and the polycrystalline biaxially textured substrate material.

  1. A novel NMR-based assay to measure circulating concentrations of branched-chain amino acids: Elevation in subjects with type 2 diabetes mellitus and association with carotid intima media thickness.

    Science.gov (United States)

    Wolak-Dinsmore, Justyna; Gruppen, Eke G; Shalaurova, Irina; Matyus, Steven P; Grant, Russell P; Gegen, Ray; Bakker, Stephan J L; Otvos, James D; Connelly, Margery A; Dullaart, Robin P F

    2018-04-01

    Plasma branched-chain amino acid (BCAA) levels, measured on nuclear magnetic resonance (NMR) metabolomics research platforms or by mass spectrometry, have been shown to be associated with type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). We developed a new test for quantification of BCAA on a clinical NMR analyzer and used this test to determine the clinical correlates of BCAA in 2 independent cohorts. The performance of the NMR-based BCAA assay was evaluated. A method comparison study was performed with mass spectrometry (LC-MS/MS). Plasma BCAA were measured in the Insulin Resistance Atherosclerosis Study (IRAS, n = 1209; 376 T2DM subjects) and in a Groningen cohort (n = 123; 67 T2DM subjects). In addition, carotid intima media thickness (cIMT) was measured successfully in 119 subjects from the Groningen cohort. NMR-based BCAA assay results were linear over a range of concentrations. Coefficients of variation for inter- and intra-assay precision ranged from 1.8-6.0, 1.7-5.4, 4.4-9.1, and 8.8-21.3%, for total BCAA, valine, leucine, and isoleucine, respectively. BCAA quantified from the same samples using NMR and LC-MS/MS were highly correlated (R 2  = 0.97, 0.95 and 0.90 for valine, leucine and isoleucine). In both cohorts total and individual BCAA were elevated in T2DM (P = 0.01 to ≤0.001). Moreover, cIMT was associated with BCAA independent of age, sex, T2DM and metabolic syndrome (MetS) categorization or alternatively of individual MetS components. BCAA levels, measured by NMR in the clinical laboratory, are elevated in T2DM and may be associated with cIMT, a proxy of subclinical atherosclerosis. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Flow-injection chemiluminescence assay for ultra-trace determination of DNA using rhodamine B-Ce(IV)-DNA ternary system in sulfuric acid media

    International Nuclear Information System (INIS)

    Ma Yongjun; Zhou Min; Jin Xiaoyong; Zhang Ziyu; Teng Xiulan; Chen Hui

    2004-01-01

    A novel flow-injection chemiluminescence method for the determination of DNA at ultra-trace level has been established. In 0.8 M sulfuric acid media, the chemiluminescence of the rhodamine B-cerium (IV) or Ce(IV) system is enhanced by DNA, activated previously by imidazole-HCl buffer solution (pH 7.0). The enhanced intensity of chemiluminescence is in proportion to log DNA concentration 1.0x10 -8 to 0.1 μg ml -1 for herring sperm DNA and 2.0x10 -6 to 0.2 μg ml -1 for calf thymus DNA with 3σ detection limits of 8.3x10 -9 μg ml -1 for herring sperm DNA and 3.5x10 -7 μg ml -1 for calf thymus DNA, respectively. The relative standard deviation for 1.0x10 -4 μg ml -1 herring sperm DNA was 0.99% and 2.0x10 -3 μg ml -1 for calf thymus DNA was 1.1% (n=11). Using the optimized system, DNA contents in six synthetic samples has been determined with recoveries of 99.5-109.0%. The possible mechanism has also been studied in this paper

  3. Flow-injection chemiluminescence assay for ultra-trace determination of DNA using rhodamine B-Ce(IV)-DNA ternary system in sulfuric acid media

    Energy Technology Data Exchange (ETDEWEB)

    Ma Yongjun; Zhou Min; Jin Xiaoyong; Zhang Ziyu; Teng Xiulan; Chen Hui

    2004-01-09

    A novel flow-injection chemiluminescence method for the determination of DNA at ultra-trace level has been established. In 0.8 M sulfuric acid media, the chemiluminescence of the rhodamine B-cerium (IV) or Ce(IV) system is enhanced by DNA, activated previously by imidazole-HCl buffer solution (pH 7.0). The enhanced intensity of chemiluminescence is in proportion to log DNA concentration 1.0x10{sup -8} to 0.1 {mu}g ml{sup -1} for herring sperm DNA and 2.0x10{sup -6} to 0.2 {mu}g ml{sup -1} for calf thymus DNA with 3{sigma} detection limits of 8.3x10{sup -9} {mu}g ml{sup -1} for herring sperm DNA and 3.5x10{sup -7} {mu}g ml{sup -1} for calf thymus DNA, respectively. The relative standard deviation for 1.0x10{sup -4} {mu}g ml{sup -1} herring sperm DNA was 0.99% and 2.0x10{sup -3} {mu}g ml{sup -1} for calf thymus DNA was 1.1% (n=11). Using the optimized system, DNA contents in six synthetic samples has been determined with recoveries of 99.5-109.0%. The possible mechanism has also been studied in this paper.

  4. Neutron Based Non-Destructive Assay (NDA) Measurement Systems for Safeguard

    Energy Technology Data Exchange (ETDEWEB)

    Swinhoe, Martyn Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-21

    The objectives of this project are to introduce the assay methods for plutonium measurements using the HLNC; introduce the assay method for bulk uranium measurements using the AWCC; and introduce the assay method for fuel assembly measurements using the UNCL.

  5. Superductile bulk metallic glass

    International Nuclear Information System (INIS)

    Yao, K.F.; Ruan, F.; Yang, Y.Q.; Chen, N.

    2006-01-01

    Usually, monolithic bulk metallic glasses undergo inhomogeneous plastic deformation and exhibit poor ductility (<2%) at room temperature. We report a newly developed Pd-Si binary bulk metallic glass, which exhibits a uniform plastic deformation and a large plastic engineering strain of 82% and a plastic true strain of 170%, together with initial strain hardening, slight strain softening and final strain hardening characteristics. The uniform shear deformation and the ultrahigh plasticity are mainly attributed to strain hardening, which results from the nanoscale inhomogeneity due to liquid phase separation. The formed nanoscale inhomogeneity will hinder, deflect, and bifurcate the propagation of shear bands

  6. Auctioning Bulk Mobile Messages

    NARCIS (Netherlands)

    S. Meij (Simon); L-F. Pau (Louis-François); H.W.G.M. van Heck (Eric)

    2003-01-01

    textabstractThe search for enablers of continued growth of SMS traffic, as well as the take-off of the more diversified MMS message contents, open up for enterprises the potential of bulk use of mobile messaging , instead of essentially one-by-one use. In parallel, such enterprises or value added

  7. Diffusion or bulk flow

    DEFF Research Database (Denmark)

    Schulz, Alexander

    2015-01-01

    is currently matter of discussion, called passive symplasmic loading. Based on the limited material available, this review compares the different loading modes and suggests that diffusion is the driving force in apoplasmic loaders, while bulk flow plays an increasing role in plants having a continuous...

  8. Ferromagnetic bulk glassy alloys

    International Nuclear Information System (INIS)

    Inoue, Akihisa; Makino, Akihiro; Mizushima, Takao

    2000-01-01

    This paper deals with the review on the formation, thermal stability and magnetic properties of the Fe-based bulk glassy alloys in as-cast bulk and melt-spun ribbon forms. A large supercooled liquid region over 50 K before crystallization was obtained in Fe-(Al, Ga)-(P, C, B, Si), Fe-(Cr, Mo, Nb)-(Al, Ga)-(P, C, B) and (Fe, Co, Ni)-Zr-M-B (M=Ti, Hf, V, Nb, Ta, Cr, Mo and W) systems and bulk glassy alloys were produced in a thickness range below 2 mm for the Fe-(Al, Ga)-(P, C, B, Si) system and 6 mm for the Fe-Co-(Zr, Nb, Ta)-(Mo, W)-B system by copper-mold casting. The ring-shaped glassy Fe-(Al, Ga)-(P, C, B, Si) alloys exhibit much better soft magnetic properties as compared with the ring-shaped alloy made from the melt-spun ribbon because of the formation of the unique domain structure. The good combination of high glass-forming ability and good soft magnetic properties indicates the possibility of future development as a new bulk glassy magnetic material

  9. Characterisation of bulk solids

    Energy Technology Data Exchange (ETDEWEB)

    D. McGlinchey [Glasgow Caledonian University, Glasgow (United Kingdom). Centre for Industrial Bulk Solids Handling

    2005-07-01

    Handling of powders and bulk solids is a critical industrial technology across a broad spectrum of industries, including minerals processing. With contributions from leading authors in their respective fields, this book provides the reader with a sound understanding of the techniques, importance and application of particulate materials characterisation. It covers the fundamental characteristics of individual particles and bulk particulate materials, and includes discussion of a wide range of measurement techniques, and the use of material characteristics in design and industrial practice. Contents: Characterising particle properties; Powder mechanics and rheology; Characterisation for hopper and stockpile design; Fluidization behaviour; Characterisation for pneumatic conveyor design; Explosiblility; 'Designer' particle characteristics; Current industrial practice; and Future trends. 130 ills.

  10. Micromegas in a bulk

    International Nuclear Information System (INIS)

    Giomataris, I.; De Oliveira, R.; Andriamonje, S.; Aune, S.; Charpak, G.; Colas, P.; Fanourakis, G.; Ferrer, E.; Giganon, A.; Rebourgeard, Ph.; Salin, P.

    2006-01-01

    In this paper, we present a novel way to manufacture the bulk Micromegas detector. A simple process based on the Printed Circuit Board (PCB) technology is employed to produce the entire sensitive detector. Such a fabrication process could be extended to very large area detectors made by the industry. The low cost fabrication together with the robustness of the electrode materials will make it attractive for several applications ranging from particle physics and astrophysics to medicine

  11. Hormone assay

    International Nuclear Information System (INIS)

    Eisentraut, A.M.

    1977-01-01

    An improved radioimmunoassay is described for measuring total triiodothyronine or total thyroxine levels in a sample of serum containing free endogenous thyroid hormone and endogenous thyroid hormone bound to thyroid hormone binding protein. The thyroid hormone is released from the protein by adding hydrochloric acid to the serum. The pH of the separated thyroid hormone and thyroid hormone binding protein is raised in the absence of a blocking agent without interference from the endogenous protein. 125 I-labelled thyroid hormone and thyroid hormone antibodies are added to the mixture, allowing the labelled and unlabelled thyroid hormone and the thyroid hormone antibody to bind competitively. This results in free thyroid hormone being separated from antibody bound thyroid hormone and thus the unknown quantity of thyroid hormone may be determined. A thyroid hormone test assay kit is described for this radioimmunoassay. It provides a 'single tube' assay which does not require blocking agents for endogenous protein interference nor an external solid phase sorption step for the separation of bound and free hormone after the competitive binding step; it also requires a minimum number of manipulative steps. Examples of the assay are given to illustrate the reproducibility, linearity and specificity of the assay. (UK)

  12. Assay system

    International Nuclear Information System (INIS)

    Patzke, J.B.; Rosenberg, B.J.

    1984-01-01

    The accuracy of assays for monitoring concentrations of basic drugs in biological fluids containing a 1 -acid glycoproteins, such as blood (serum or plasma), is improved by the addition of certain organic phosphate compounds to minimize the ''protein effect.'' Kits containing the elements of the invention are also disclosed

  13. Bulk monitoring and segregation of radioactive wastes

    Energy Technology Data Exchange (ETDEWEB)

    Beddow, H.; Adsley, I.; Pearman, I.; Sweeney, A.; Davies, M., E-mail: helen.beddow@nuvia.co.uk [Nuvia Limited, Harwell Oxford, Didcot, Oxfordshire (United Kingdom)

    2014-07-01

    Several sites in the UK are contaminated by radioactive legacy wastes. These include; radium luminising sites and more recently the oil, and (potentially) fracking industries; sites contaminated from thorium gas mantle factories; old nuclear research sites; nuclear power sites, and the Sellafield reprocessing site. Nuvia has developed a suite of technologies to map the location of and to recover and process wastes during remedial operations. The main method for delineating contaminated areas in-situ is by use of the Groundhog system, whilst bulk monitoring methods employ the Gamma Excavation Monitor, the High Resolution Assay Monitor, and the Conveyor Active Particle System. (author)

  14. Bulk monitoring and segregation of radioactive wastes

    International Nuclear Information System (INIS)

    Beddow, H.; Adsley, I.; Pearman, I.; Sweeney, A.; Davies, M.

    2014-01-01

    Several sites in the UK are contaminated by radioactive legacy wastes. These include; radium luminising sites and more recently the oil, and (potentially) fracking industries; sites contaminated from thorium gas mantle factories; old nuclear research sites; nuclear power sites, and the Sellafield reprocessing site. Nuvia has developed a suite of technologies to map the location of and to recover and process wastes during remedial operations. The main method for delineating contaminated areas in-situ is by use of the Groundhog system, whilst bulk monitoring methods employ the Gamma Excavation Monitor, the High Resolution Assay Monitor, and the Conveyor Active Particle System. (author)

  15. Bulk-Fill Resin Composites

    DEFF Research Database (Denmark)

    Benetti, Ana Raquel; Havndrup-Pedersen, Cæcilie; Honoré, Daniel

    2015-01-01

    the restorative procedure. The aim of this study, therefore, was to compare the depth of cure, polymerization contraction, and gap formation in bulk-fill resin composites with those of a conventional resin composite. To achieve this, the depth of cure was assessed in accordance with the International Organization...... for Standardization 4049 standard, and the polymerization contraction was determined using the bonded-disc method. The gap formation was measured at the dentin margin of Class II cavities. Five bulk-fill resin composites were investigated: two high-viscosity (Tetric EvoCeram Bulk Fill, SonicFill) and three low......-viscosity (x-tra base, Venus Bulk Fill, SDR) materials. Compared with the conventional resin composite, the high-viscosity bulk-fill materials exhibited only a small increase (but significant for Tetric EvoCeram Bulk Fill) in depth of cure and polymerization contraction, whereas the low-viscosity bulk...

  16. Escape angles in bulk chi((2)) soliton interactions

    DEFF Research Database (Denmark)

    Johansen, Steffen Kjær; Bang, Ole; Sørensen, Mads Peter

    2002-01-01

    We develop a theory for nonplanar interaction between two identical type I spatial solitons propagating at opposite, but arbitrary transverse angles in quadratic nonlinear (or so-called chi((2))) bulk, media. We predict quantitatively the outwards escape angle, below which the solitons turn around...

  17. Determination of Tolterodine tartrate in bulk and formulation by ...

    African Journals Online (AJOL)

    Purpose: To develop a new simple, accurate, precise and fully validated extractive colorimetric method for the determination of tolterodine tartrate (TL) in bulk and in tablet dosage form, Method: A chloroform extractable orange red complex formed between the acid dye, tropaeolin OOO-1 and tolterodine in acid media is the ...

  18. Bulk muscles, loose cables.

    Science.gov (United States)

    Liyanage, Chamari R D G; Kodali, Venkata

    2014-10-17

    The accessibility and usage of body building supplements is on the rise with stronger internet marketing strategies by the industry. The dangers posed by the ingredients in them are underestimated. A healthy young man came to the emergency room with palpitations and feeling unwell. Initial history and clinical examination were non-contributory to find the cause. ECG showed atrial fibrillation. A detailed history for any over the counter or herbal medicine use confirmed that he was taking supplements to bulk muscle. One of the components in these supplements is yohimbine; the onset of symptoms coincided with the ingestion of this product and the patient is symptom free after stopping it. This report highlights the dangers to the public of consuming over the counter products with unknown ingredients and the consequential detrimental impact on health. 2014 BMJ Publishing Group Ltd.

  19. SOCIAL MEDIA

    Science.gov (United States)

    RESPONSIBILITY CENTCOM COALITION MEDIA SOCIAL MEDIA NEWS ARTICLES PRESS RELEASES IMAGERY VIDEOS TRANSCRIPTS VISITORS AND PERSONNEL FAMILY CENTER FAMILY READINESS CENTCOM WEBMAIL SOCIAL MEDIA SECURITY ACCOUNTABILITY HomeMEDIASOCIAL MEDIA Social Media CENTCOM'S ENGLISH SOCIAL MEDIA ACCOUNTS There are many U.S. military commands

  20. Microfabricated Bulk Piezoelectric Transformers

    Science.gov (United States)

    Barham, Oliver M.

    Piezoelectric voltage transformers (PTs) can be used to transform an input voltage into a different, required output voltage needed in electronic and electro- mechanical systems, among other varied uses. On the macro scale, they have been commercialized in electronics powering consumer laptop liquid crystal displays, and compete with an older, more prevalent technology, inductive electromagnetic volt- age transformers (EMTs). The present work investigates PTs on smaller size scales that are currently in the academic research sphere, with an eye towards applications including micro-robotics and other small-scale electronic and electromechanical sys- tems. PTs and EMTs are compared on the basis of power and energy density, with PTs trending towards higher values of power and energy density, comparatively, indicating their suitability for small-scale systems. Among PT topologies, bulk disc-type PTs, operating in their fundamental radial extension mode, and free-free beam PTs, operating in their fundamental length extensional mode, are good can- didates for microfabrication and are considered here. Analytical modeling based on the Extended Hamilton Method is used to predict device performance and integrate mechanical tethering as a boundary condition. This model differs from previous PT models in that the electric enthalpy is used to derive constituent equations of motion with Hamilton's Method, and therefore this approach is also more generally applica- ble to other piezoelectric systems outside of the present work. Prototype devices are microfabricated using a two mask process consisting of traditional photolithography combined with micropowder blasting, and are tested with various output electri- cal loads. 4mm diameter tethered disc PTs on the order of .002cm. 3 , two orders smaller than the bulk PT literature, had the followingperformance: a prototype with electrode area ratio (input area / output area) = 1 had peak gain of 2.3 (+/- 0.1), efficiency of 33 (+/- 0

  1. Bulk photovoltaic effect in photoconductive metamaterials based on cone-shaped nanoparticles

    DEFF Research Database (Denmark)

    Zhukovsky, Sergei; Babicheva, Viktoriia; Uskov, Alexander V.

    2014-01-01

    is the directanalogy of the photogalvanic effect known to exist in naturally occurring non-centrosymmetric media. This plasmonic bulk photovoltaic effect is intermediate between the inner photoelectric effect in bulk media and the outer photoelectric effect atmacroscopic interfaces. The results obtained are valuable...... for characterizing photoemission and photoconductive properties of plasmonic nanostructures. They can find many uses for photodetection-related and photovoltaic applications...

  2. Developing bulk exchange spring magnets

    Science.gov (United States)

    Mccall, Scott K.; Kuntz, Joshua D.

    2017-06-27

    A method of making a bulk exchange spring magnet by providing a magnetically soft material, providing a hard magnetic material, and producing a composite of said magnetically soft material and said hard magnetic material to make the bulk exchange spring magnet. The step of producing a composite of magnetically soft material and hard magnetic material is accomplished by electrophoretic deposition of the magnetically soft material and the hard magnetic material to make the bulk exchange spring magnet.

  3. Mining the bulk positron lifetime

    International Nuclear Information System (INIS)

    Aourag, H.; Guittom, A.

    2009-01-01

    We introduce a new approach to investigate the bulk positron lifetimes of new systems based on data-mining techniques. Through data mining of bulk positron lifetimes, we demonstrate the ability to predict the positron lifetimes of new semiconductors on the basis of available semiconductor data already studied. Informatics techniques have been applied to bulk positron lifetimes for different tetrahedrally bounded semiconductors in order to discover computational design rules. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  4. Media education.

    Science.gov (United States)

    Strasburger, Victor C

    2010-11-01

    The American Academy of Pediatrics recognizes that exposure to mass media (eg, television, movies, video and computer games, the Internet, music lyrics and videos, newspapers, magazines, books, advertising) presents health risks for children and adolescents but can provide benefits as well. Media education has the potential to reduce the harmful effects of media and accentuate the positive effects. By understanding and supporting media education, pediatricians can play an important role in reducing harmful effects of media on children and adolescents.

  5. Modelling of bulk superconductor magnetization

    International Nuclear Information System (INIS)

    Ainslie, M D; Fujishiro, H

    2015-01-01

    This paper presents a topical review of the current state of the art in modelling the magnetization of bulk superconductors, including both (RE)BCO (where RE = rare earth or Y) and MgB 2 materials. Such modelling is a powerful tool to understand the physical mechanisms of their magnetization, to assist in interpretation of experimental results, and to predict the performance of practical bulk superconductor-based devices, which is particularly important as many superconducting applications head towards the commercialization stage of their development in the coming years. In addition to the analytical and numerical techniques currently used by researchers for modelling such materials, the commonly used practical techniques to magnetize bulk superconductors are summarized with a particular focus on pulsed field magnetization (PFM), which is promising as a compact, mobile and relatively inexpensive magnetizing technique. A number of numerical models developed to analyse the issues related to PFM and optimise the technique are described in detail, including understanding the dynamics of the magnetic flux penetration and the influence of material inhomogeneities, thermal properties, pulse duration, magnitude and shape, and the shape of the magnetization coil(s). The effect of externally applied magnetic fields in different configurations on the attenuation of the trapped field is also discussed. A number of novel and hybrid bulk superconductor structures are described, including improved thermal conductivity structures and ferromagnet–superconductor structures, which have been designed to overcome some of the issues related to bulk superconductors and their magnetization and enhance the intrinsic properties of bulk superconductors acting as trapped field magnets. Finally, the use of hollow bulk cylinders/tubes for shielding is analysed. (topical review)

  6. Bulk sample self-attenuation correction by transmission measurement

    International Nuclear Information System (INIS)

    Parker, J.L.; Reilly, T.D.

    1976-01-01

    Various methods used in either finding or avoiding the attenuation correction in the passive γ-ray assay of bulk samples are reviewed. Detailed consideration is given to the transmission method, which involves experimental determination of the sample linear attenuation coefficient by measuring the transmission through the sample of a beam of gamma rays from an external source. The method was applied to box- and cylindrically-shaped samples

  7. Bulk metallic glass matrix composites

    International Nuclear Information System (INIS)

    Choi-Yim, H.; Johnson, W.L.

    1997-01-01

    Composites with a bulk metallic glass matrix were synthesized and characterized. This was made possible by the recent development of bulk metallic glasses that exhibit high resistance to crystallization in the undercooled liquid state. In this letter, experimental methods for processing metallic glass composites are introduced. Three different bulk metallic glass forming alloys were used as the matrix materials. Both ceramics and metals were introduced as reinforcement into the metallic glass. The metallic glass matrix remained amorphous after adding up to a 30 vol% fraction of particles or short wires. X-ray diffraction patterns of the composites show only peaks from the second phase particles superimposed on the broad diffuse maxima from the amorphous phase. Optical micrographs reveal uniformly distributed particles in the matrix. The glass transition of the amorphous matrix and the crystallization behavior of the composites were studied by calorimetric methods. copyright 1997 American Institute of Physics

  8. 21 CFR 884.6180 - Reproductive media and supplements.

    Science.gov (United States)

    2010-04-01

    ... used for assisted reproduction procedures. Media include liquid and powder versions of various..., antibiotics, etc.). (b) Classification. Class II (special controls) (mouse embryo assay information, endotoxin...

  9. Media Komunitas dan Media Literacy

    Directory of Open Access Journals (Sweden)

    Pawito .

    2013-12-01

    Full Text Available Abstract:This essay deals with community media in relation to media literacy. After a short discussion on a number of community media characters is made the essay goes further with somewhat detail theoretical presumptions of the roles of media community with respect primarily to the development as Amartya Sen mentioned about. The author suggests that community media may play some significant roles in the development including (a disseminating information (from varieties of perspective, (b facilitating public discussion, (c helping to reach solutions of problems, (d encouraging participations, and (e encouraging the development of media literacy. Regarding the last point the author remarks that media community may have a dual-roles i.e facilitating community’s member in media participation and facilitating community’s member in media education.

  10. Bulk viscosity and cosmological evolution

    International Nuclear Information System (INIS)

    Beesham, A.

    1996-01-01

    In a recent interesting paper, Pimentel and Diaz-Rivera (Nuovo Cimento B, 109(1994) 1317) have derived several solutions with bulk viscosity in homogeneous and isotropic cosmological models. They also discussed the properties of these solutions. In this paper the authors relate the solutions of Pimentel and Diaz-Rivera by simple transformations to previous solutions published in the literature, showing that all the solutions can be derived from the known existing ones. Drawbacks to these approaches of studying bulk viscosity are pointed out, and better approaches indicated

  11. Molecular epidemiology of malaria in Cameroon. XV. Experimental studies on serum substitutes and supplements and alternative culture media for in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum.

    Science.gov (United States)

    Basco, Leonardo K

    2003-08-01

    In vitro drug sensitivity assay is an important tool for various on-going studies aiming to establish the correlation between candidate molecular markers for drug resistance and drug response in laboratory-adapted strains and field isolates of Plasmodium falciparum. A widespread use of this technique in the field would require a suitable substitute that can replace human serum. In this study, several alternative sources of serum substitutes and supplements were evaluated for their capacity to sustain parasite growth for a single life cycle and their compatibility with in vitro assays for clinical isolates that have not been adapted to in vitro culture. Albumax, a commercial preparation of lipid-enriched bovine albumin, did not support parasite growth as much as human serum and fetal calf serum in several isolates. Other serum supplements (AmnioMax and Ultroser) supported parasite growth relatively well. The 50% inhibitory concentrations (IC50s) of chloroquine and antifolates determined with 0.05% Albumax were generally two or three times higher than with human serum. With 10% fetal calf serum, IC50s for chloroquine and antifolates were approximately two times higher and three times lower than with human serum, respectively. The use of AmnioMax and OptiMAb resulted in a greater than two-fold increase in IC50s and several uninterpretable assays. Despite possible batch-to-batch differences, fetal calf serum may be a suitable substitute for in vitro drug assays while awaiting the results of further studies on other serum substitutes and supplements.

  12. Radiometric assays for glycerol, glucose, and glycogen

    International Nuclear Information System (INIS)

    Bradley, D.C.; Kaslow, H.R.

    1989-01-01

    We have developed radiometric assays for small quantities of glycerol, glucose and glycogen, based on a technique described by Thorner and Paulus for the measurement of glycerokinase activity. In the glycerol assay, glycerol is phosphorylated with [32P]ATP and glycerokinase, residual [32P]ATP is hydrolyzed by heating in acid, and free [32P]phosphate is removed by precipitation with ammonium molybdate and triethylamine. Standard dose-response curves were linear from 50 to 3000 pmol glycerol with less than 3% SD in triplicate measurements. Of the substances tested for interference, only dihydroxyacetone gave a slight false positive signal at high concentration. When used to measure glycerol concentrations in serum and in media from incubated adipose tissue, the radiometric glycerol assay correlated well with a commonly used spectrophotometric assay. The radiometric glucose assay is similar to the glycerol assay, except that glucokinase is used instead of glycerokinase. Dose response was linear from 5 to 3000 pmol glucose with less than 3% SD in triplicate measurements. Glucosamine and N-acetylglucosamine gave false positive signals when equimolar to glucose. When glucose concentrations in serum were measured, the radiometric glucose assay agreed well with hexokinase/glucose-6-phosphate dehydrogenase (H/GDH)-based and glucose oxidase/H2O2-based glucose assays. The radiometric method for glycogen measurement incorporates previously described isolation and digestion techniques, followed by the radiometric assay of free glucose. When used to measure glycogen in mouse epididymal fat pads, the radiometric glycogen assay correlated well with the H/GDH-based glycogen assay. All three radiometric assays offer several practical advantages over spectral assays

  13. Zirconium based bulk metallic glasses

    International Nuclear Information System (INIS)

    Dey, G.K.; Neogy, S.; Savalia, R.T.; Tewari, R.; Srivastava, D.; Banerjee, S.

    2006-01-01

    Metallic glasses have come into prominence in recent times because their nanocrystalline atomic arrangement imparts many useful and unusual properties to these metallic solids. In this study, bulk glasses have been obtained in Zr based multicomponent alloy by induction melting these alloys in silica crucibles and casting these in form of rods 3 and 6 mm in diameter in a copper mould

  14. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja

    2009-01-01

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise...

  15. Bulk viscosity of molecular fluids

    Science.gov (United States)

    Jaeger, Frederike; Matar, Omar K.; Müller, Erich A.

    2018-05-01

    The bulk viscosity of molecular models of gases and liquids is determined by molecular simulations as a combination of a dilute gas contribution, arising due to the relaxation of internal degrees of freedom, and a configurational contribution, due to the presence of intermolecular interactions. The dilute gas contribution is evaluated using experimental data for the relaxation times of vibrational and rotational degrees of freedom. The configurational part is calculated using Green-Kubo relations for the fluctuations of the pressure tensor obtained from equilibrium microcanonical molecular dynamics simulations. As a benchmark, the Lennard-Jones fluid is studied. Both atomistic and coarse-grained force fields for water, CO2, and n-decane are considered and tested for their accuracy, and where possible, compared to experimental data. The dilute gas contribution to the bulk viscosity is seen to be significant only in the cases when intramolecular relaxation times are in the μs range, and for low vibrational wave numbers (<1000 cm-1); This explains the abnormally high values of bulk viscosity reported for CO2. In all other cases studied, the dilute gas contribution is negligible and the configurational contribution dominates the overall behavior. In particular, the configurational term is responsible for the enhancement of the bulk viscosity near the critical point.

  16. Locative media

    CERN Document Server

    Wilken, Rowan

    2014-01-01

    Not only is locative media one of the fastest growing areas in digital technology, but questions of location and location-awareness are increasingly central to our contemporary engagements with online and mobile media, and indeed media and culture generally. This volume is a comprehensive account of the various location-based technologies, services, applications, and cultures, as media, with an aim to identify, inventory, explore, and critique their cultural, economic, political, social, and policy dimensions internationally. In particular, the collection is organized around the perception that the growth of locative media gives rise to a number of crucial questions concerning the areas of culture, economy, and policy.

  17. Media Entrepreneurship

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2017-01-01

    Media Entrepreneurship has been an ambiguous, unclear and controversial concept and despite of growing academic efforts in the last decade, it is still a poorly defined subject. This paper is an effort to fill this gap by providing a comprehensive definition of media entrepreneurship. Firstly......, a literature review conducted and entrepreneurship, media, opportunity and innovation as building blocks of media entrepreneurship explained. Then by using of a mixed of bibliographic method and a Delphi method with multi-stage analysis process, a consensual definition of media entrepreneurship proposed...... entrepreneurship....

  18. Media Framing

    DEFF Research Database (Denmark)

    Pedersen, Rasmus T.

    2017-01-01

    The concept of media framing refers to the way in which the news media organize and provide meaning to a news story by emphasizing some parts of reality and disregarding other parts. These patterns of emphasis and exclusion in news coverage create frames that can have considerable effects on news...... consumers’ perceptions and attitudes regarding the given issue or event. This entry briefly elaborates on the concept of media framing, presents key types of media frames, and introduces the research on media framing effects....

  19. Sensitive Media

    Directory of Open Access Journals (Sweden)

    Malinowska Anna

    2017-12-01

    Full Text Available The paper engages with what we refer to as “sensitive media,” a concept associated with developments in the overall media environment, our relationships with media devices, and the quality of the media themselves. Those developments point to the increasing emotionality of the media world and its infrastructures. Mapping the trajectories of technological development and impact that the newer media exert on human condition, our analysis touches upon various forms of emergent affect, emotion, and feeling in order to trace the histories and motivations of the sensitization of “the media things” as well as the redefinition of our affective and emotional experiences through technologies that themselves “feel.”

  20. Media Ecology

    Directory of Open Access Journals (Sweden)

    Marina Ašković

    2015-05-01

    Full Text Available Does the trend in which electronic media are gradually becoming extension of human body have to move towards full enslavement of a human and his personality, or the same human will unpredictably, with the aid of his personal media literacy, exit the whirls of media and technological censorships? Personality crisis is closely related to the crisis of language no matter how contradicted to global ideology of transnational transhumanism it may seem. Considering the fact that recent media presentations of the world are based on commercialization of environmentalism, philosophical and aesthetic thought appears as an important subject of ecology. As media mediates, the scenery of civilized living increasingly becomes more appealing even though it derives from commercial and political background. Consequently, the future of humanity depends by large on the philosophy of media. Media have to truly ecologise returning the humanum to its essence making it into the extension of the natural world.

  1. New low-viscosity overlay medium for viral plaque assays

    Directory of Open Access Journals (Sweden)

    Garten Wolfgang

    2006-08-01

    Full Text Available Abstract Background Plaque assays in cell culture monolayers under solid or semisolid overlay media are commonly used for quantification of viruses and antiviral substances. To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CL™ as overlay media in the plaque and plaque-inhibition assay of influenza viruses. Results Significantly larger plaques were formed under Avicel-containing media, as compared to agar and methylcellulose (MC overlay media. The plaque size increased with decreasing Avicel concentration, but even very diluted Avicel overlays (0.3% ensured formation of localized plaques. Due to their low viscosity, Avicel overlays were easier to use than methylcellulose overlays, especially in the 96-well culture plates. Furthermore, Avicel overlay could be applied without prior removal of the virus inoculum thus facilitating the assay and reducing chances of cross-contamination. Using neuraminidase inhibitor oseltamivir carboxylate, we demonstrated applicability of the Avicel-based plaque reduction assay for testing of antiviral substances. Conclusion Plaque assay under Avicel-containing overlay media is easier, faster and more sensitive than assays under agar- and methylcellulose overlays. The assay can be readily performed in a 96-well plate format and seems particularly suitable for high-throughput virus titrations, serological studies and experiments on viral drug sensitivity. It may also facilitate work with highly pathogenic agents performed under hampered conditions of bio-safety labs.

  2. Coulombic Fluids Bulk and Interfaces

    CERN Document Server

    Freyland, Werner

    2011-01-01

    Ionic liquids have attracted considerable interest in recent years. In this book the bulk and interfacial physico-chemical characteristics of various fluid systems dominated by Coulomb interactions are treated which includes molten salts, ionic liquids as well as metal-molten salt mixtures and expanded fluid metals. Of particular interest is the comparison of the different systems. Topics in the bulk phase concern the microscopic structure, the phase behaviour and critical phenomena, and the metal-nonmetal transition. Interfacial phenomena include wetting transitions, electrowetting, surface freezing, and the electrified ionic liquid/ electrode interface. With regard to the latter 2D and 3D electrochemical phase formation of metals and semi-conductors on the nanometer scale is described for a number of selected examples. The basic concepts and various experimental methods are introduced making the book suitable for both graduate students and researchers interested in Coulombic fluids.

  3. Bulk Superconductors in Mobile Application

    Science.gov (United States)

    Werfel, F. N.; Delor, U. Floegel-; Rothfeld, R.; Riedel, T.; Wippich, D.; Goebel, B.; Schirrmeister, P.

    We investigate and review concepts of multi - seeded REBCO bulk superconductors in mobile application. ATZ's compact HTS bulk magnets can trap routinely 1 T@77 K. Except of magnetization, flux creep and hysteresis, industrial - like properties as compactness, power density, and robustness are of major device interest if mobility and light-weight construction is in focus. For mobile application in levitated trains or demonstrator magnets we examine the performance of on-board cryogenics either by LN2 or cryo-cooler application. The mechanical, electric and thermodynamical requirements of compact vacuum cryostats for Maglev train operation were studied systematically. More than 30 units are manufactured and tested. The attractive load to weight ratio is more than 10 and favours group module device constructions up to 5 t load on permanent magnet (PM) track. A transportable and compact YBCO bulk magnet cooled with in-situ 4 Watt Stirling cryo-cooler for 50 - 80 K operation is investigated. Low cooling power and effective HTS cold mass drives the system construction to a minimum - thermal loss and light-weight design.

  4. Media Flow

    DEFF Research Database (Denmark)

    Kabel, Lars

    2016-01-01

    News and other kinds of journalistic stories, 16-17 hours a day, all year round, on all platforms, also the moderated social media. The key research thesis behind this article is that the continuous and speedy stream of news stories and media content now is becoming the centre of the production...... processes and the value creation in converged multimedia newsrooms. The article identify new methods and discuss editorial challenges in handling media flow....

  5. Assay of low-enriched uranium using spontaneous fission neutrons

    International Nuclear Information System (INIS)

    Zucker, M.S.; Fainberg, A.

    1980-01-01

    Low-enriched uranium oxide in bulk containers can be assayed for safeguards purposes, using the neutrons from spontaneous fission of 238 U as a signature, to complement enrichment and mass measurement. The penetrability of the fast fission neutrons allows the inner portion of bulk samples to register. The measurement may also be useful for measuring moisture content, of significance in process control. The apparatus used can be the same as for neutron correlation counting for Pu assay. The neutron multiplication observed in 238 U is of intrinsic interest

  6. Signed Networks in Social Media

    OpenAIRE

    Leskovec, Jure; Huttenlocher, Daniel; Kleinberg, Jon

    2010-01-01

    Relations between users on social media sites often reflect a mixture of positive (friendly) and negative (antagonistic) interactions. In contrast to the bulk of research on social networks that has focused almost exclusively on positive interpretations of links between people, we study how the interplay between positive and negative relationships affects the structure of on-line social networks. We connect our analyses to theories of signed networks from social psychology. We find that the c...

  7. Instructional Media

    African Journals Online (AJOL)

    This can be summed up in a few words: Students can learn a great deal from any of the media. Under most of the conditions tested, they could learn as much as from ... Beyond physical conditions (deafness) there is little reason to expect a differential media. Scientia Militaria, South African Journal of Military Studies, Vol 13 ...

  8. Mixed Media

    Science.gov (United States)

    Peterson, Erin

    2010-01-01

    While institutions do not often have a hook as compelling as an eagerly awaited movie, great content is critical for media relations success--and coupling it with the right distribution channel can ensure the story finds the right audience. Even better, retooling it for several media platforms can extend the life and reach of a story. The changes…

  9. Media darling

    CERN Multimedia

    Chalmers, Matthew

    2008-01-01

    He is the media-friendly face of particle physics, appearing on countless TV and radio shows in the run-up to the opening of CERN's Large Hadron Collider. Matthew Chalmers discovers how Brian Cox finds the time to be both a physicist and a media personality. (2 pages)

  10. Media Art

    DEFF Research Database (Denmark)

    Ekman, Ulrik

    2015-01-01

    environments, experience time, and develop identities individually and socially. Interviews with working media artists lend further perspectives on these cultural transformations. Drawing on cultural theory, new media art studies, human-computer interaction theory, and software studies, this cutting-edge book...... critically unpacks the complex ubiquity-effects confronting us every day....

  11. Ordered bulk degradation via autophagy

    DEFF Research Database (Denmark)

    Dengjel, Jörn; Kristensen, Anders Riis; Andersen, Jens S

    2008-01-01

    During amino acid starvation, cells undergo macroautophagy which is regarded as an unspecific bulk degradation process. Lately, more and more organelle-specific autophagy subtypes such as reticulophagy, mitophagy and ribophagy have been described and it could be shown, depending on the experimental...... at proteasomal and lysosomal degradation ample cross-talk between the two degradation pathways became evident. Degradation via autophagy appeared to be ordered and regulated at the protein complex/organelle level. This raises several important questions such as: can macroautophagy itself be specific and what...

  12. Bulk functionalization of graphene using diazonium compounds and amide reaction

    Science.gov (United States)

    Peng, Chang; Xiong, Yuzi; Liu, Zhibo; Zhang, Fan; Ou, Encai; Qian, Jiangtao; Xiong, Yuanqin; Xu, Weijian

    2013-09-01

    An efficient and convenient method is applied to introduce varieties of simple functionalities onto the graphene surface for the bulk preparation, which begins with pristine graphite that does not require initial oxidative damage of the graphene basal planes. Diazonium compounds functionalized reaction is demonstrated and it successfully prevented the aggregation of graphene for which providing solubility in high polar organic media or even in volatile solvents such as ethanol and acetone. This approach is complemented by the phenyl carboxylic diazonium salt functionalized graphene (PCFG) attachment of a symmetrically substituted zinc phthalocyanine (PCFG-Pc) using the amide reaction, which is used for the covalent introduction of a complex phthalocyanine molecule.

  13. Microbead agglutination based assays

    KAUST Repository

    Kodzius, Rimantas

    2013-01-21

    We report a simple and rapid room temperature assay for point-of-care (POC) testing that is based on specific agglutination. Agglutination tests are based on aggregation of microbeads in the presence of a specific analyte thus enabling the macroscopic observation. Such tests are most often used to explore antibody-antigen reactions. Agglutination has been used for protein assays using a biotin/streptavidin system as well as a hybridization based assay. The agglutination systems are prone to selftermination of the linking analyte, prone to active site saturation and loss of agglomeration at high analyte concentrations. We investigated the molecular target/ligand interaction, explaining the common agglutination problems related to analyte self-termination, linkage of the analyte to the same bead instead of different microbeads. We classified the agglutination process into three kinds of assays: a two- component assay, a three-component assay and a stepped three- component assay. Although we compared these three kinds of assays for recognizing DNA and protein molecules, the assay can be used for virtually any molecule, including ions and metabolites. In total, the optimized assay permits detecting analytes with high sensitivity in a short time, 5 min, at room temperature. Such a system is appropriate for POC testing.

  14. Media violence.

    Science.gov (United States)

    Cantor, J

    2000-08-01

    Research on the effects of media violence is not well understood by the general public. Despite this fact, there is an overwhelming consensus in the scientific literature about the unhealthy effects of media violence. Meta-analyses show that media-violence viewing consistently is associated with higher levels of antisocial behavior, ranging from the trivial (imitative violence directed against toys) to the serious (criminal violence), with many consequential outcomes in between (acceptance of violence as a solution to problems, increased feelings of hostility, and the apparent delivery of painful stimulation to another person). Desensitization is another well-documented effect of viewing violence, which is observable in reduced arousal and emotional disturbance while witnessing violence, the reduced tendency to intervene in a fight, and less sympathy for the victims of violence. Although there is evidence that youth who are already violent are more likely to seek out violent entertainment, there is strong evidence that the relationship between violence viewing and antisocial behavior is bidirectional. There is growing evidence that media violence also engenders intense fear in children which often lasts days, months, and even years. The media's potential role in solutions to these problems is only beginning to be explored, in investigations examining the uses and effects of movie ratings, television ratings, and the V-chip, and the effects of media literacy programs and public education efforts. Future research should explore important individual differences in responses to media violence and effective ways to intervene in the negative effects.

  15. Microhardness of bulk-fill composite materials

    OpenAIRE

    Kelić, Katarina; Matić, Sanja; Marović, Danijela; Klarić, Eva; Tarle, Zrinka

    2016-01-01

    The aim of the study was to determine microhardness of high- and low-viscosity bulk-fill composite resins and compare it with conventional composite materials. Four materials of high-viscosity were tested, including three bulk-fills: QuiXfi l (QF), x-tra fil (XTF) and Tetric EvoCeram Bulk Fill (TEBCF), while nanohybrid composite GrandioSO (GSO) served as control. The other four were low-viscosity composites, three bulk-fill materials: Smart Dentin Replacement (SDR), Venus Bulk Fill (VBF) and ...

  16. Handling of bulk solids theory and practice

    CERN Document Server

    Shamlou, P A

    1990-01-01

    Handling of Bulk Solids provides a comprehensive discussion of the field of solids flow and handling in the process industries. Presentation of the subject follows classical lines of separate discussions for each topic, so each chapter is self-contained and can be read on its own. Topics discussed include bulk solids flow and handling properties; pressure profiles in bulk solids storage vessels; the design of storage silos for reliable discharge of bulk materials; gravity flow of particulate materials from storage vessels; pneumatic transportation of bulk solids; and the hazards of solid-mater

  17. Radioreceptor opioid assay

    International Nuclear Information System (INIS)

    Miller, R.J.; Chang, K.-J.

    1981-01-01

    A radioreceptor assay is described for assaying opioid drugs in biological fluids. The method enables the assay of total opioid activity, being specific for opioids as a class but lacking specificity within the class. A radio-iodinated opioid and the liquid test sample are incubated with an opiate receptor material. The percentage inhibition of the binding of the radio-iodinated compound to the opiate receptor is calculated and the opioid activity of the test liquid determined from a standard curve. Examples of preparing radio-iodinated opioids and assaying opioid activity are given. A test kit for the assay is described. Compared to other methods, this assay is cheap, easy and rapid. (U.K.)

  18. Absolute nuclear material assay

    Science.gov (United States)

    Prasad, Manoj K [Pleasanton, CA; Snyderman, Neal J [Berkeley, CA; Rowland, Mark S [Alamo, CA

    2010-07-13

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  19. Bulk handling benefits from ICT

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-11-15

    The efficiency and accuracy of bulk handling is being improved by the range of management information systems and services available today. As part of the program to extend Richards Bay Coal Terminal, Siemens is installing a manufacturing execution system which coordinates and monitors all movements of raw materials. The article also reports recent developments by AXSMarine, SunGuard Energy, Fuelworx and Railworx in providing integrated tools for tracking, managing and optimising solid/liquid fuels and rail car maintenance activities. QMASTOR Ltd. has secured a contract with Anglo Coal Australia to provide its Pit to Port.net{reg_sign} and iFuse{reg_sign} software systems across all their Australians sites, to include pit-to-product stockpile management. 2 figs.

  20. Bulk analysis using nuclear techniques

    International Nuclear Information System (INIS)

    Borsaru, M.; Holmes, R.J.; Mathew, P.J.

    1983-01-01

    Bulk analysis techniques developed for the mining industry are reviewed. Using penetrating neutron and #betta#-radiations, measurements are obtained directly from a large volume of sample (3-30 kg) #betta#-techniques were used to determine the grade of iron ore and to detect shale on conveyor belts. Thermal neutron irradiation was developed for the simultaneous determination of iron and aluminium in iron ore on a conveyor belt. Thermal-neutron activation analysis includes the determination of alumina in bauxite, and manganese and alumina in manganese ore. Fast neutron activation analysis is used to determine silicon in iron ores, and alumina and silica in bauxite. Fast and thermal neutron activation has been used to determine the soil in shredded sugar cane. (U.K.)

  1. Gassmann Theory Applies to Nanoporous Media

    Science.gov (United States)

    Gor, Gennady Y.; Gurevich, Boris

    2018-01-01

    Recent progress in extraction of unconventional hydrocarbon resources has ignited the interest in the studies of nanoporous media. Since many thermodynamic and mechanical properties of nanoscale solids and fluids differ from the analogous bulk materials, it is not obvious whether wave propagation in nanoporous media can be described using the same framework as in macroporous media. Here we test the validity of Gassmann equation using two published sets of ultrasonic measurements for a model nanoporous medium, Vycor glass, saturated with two different fluids, argon, and n-hexane. Predictions of the Gassmann theory depend on the bulk and shear moduli of the dry samples, which are known from ultrasonic measurements and the bulk moduli of the solid and fluid constituents. The solid bulk modulus can be estimated from adsorption-induced deformation or from elastic effective medium theory. The fluid modulus can be calculated according to the Tait-Murnaghan equation at the solvation pressure in the pore. Substitution of these parameters into the Gassmann equation provides predictions consistent with measured data. Our findings set up a theoretical framework for investigation of fluid-saturated nanoporous media using ultrasonic elastic wave propagation.

  2. From Augmentation Media to Meme Media.

    Science.gov (United States)

    Tanaka, Yuzuru

    Computers as meta media are now evolving from augmentation media vehicles to meme media vehicles. While an augmentation media system provides a seamlessly integrated environment of various tools and documents, meme media system provides further functions to edit and distribute tools and documents. Documents and tools on meme media can easily…

  3. Endogenous Locus Reporter Assays.

    Science.gov (United States)

    Liu, Yaping; Hermes, Jeffrey; Li, Jing; Tudor, Matthew

    2018-01-01

    Reporter gene assays are widely used in high-throughput screening (HTS) to identify compounds that modulate gene expression. Traditionally a reporter gene assay is built by cloning an endogenous promoter sequence or synthetic response elements in the regulatory region of a reporter gene to monitor transcriptional activity of a specific biological process (exogenous reporter assay). In contrast, an endogenous locus reporter has a reporter gene inserted in the endogenous gene locus that allows the reporter gene to be expressed under the control of the same regulatory elements as the endogenous gene, thus more accurately reflecting the changes seen in the regulation of the actual gene. In this chapter, we introduce some of the considerations behind building a reporter gene assay for high-throughput compound screening and describe the methods we have utilized to establish 1536-well format endogenous locus reporter and exogenous reporter assays for the screening of compounds that modulate Myc pathway activity.

  4. Coupling brane fields to bulk supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Parameswaran, Susha L. [Uppsala Univ. (Sweden). Theoretical Physics; Schmidt, Jonas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2010-12-15

    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  5. Longitudinal and bulk viscosities of expanded rubidium

    International Nuclear Information System (INIS)

    Zaheri, Ali Hossein Mohammad; Srivastava, Sunita; Tankeshwar, K

    2003-01-01

    First three non-vanishing sum rules for the bulk and longitudinal stress auto-correlation functions have been evaluated for liquid Rb at six thermodynamic states along the liquid-vapour coexistence curve. The Mori memory function formalism and the frequency sum rules have been used to calculate bulk and longitudinal viscosities. The results thus obtained for the ratio of bulk viscosity to shear viscosity have been compared with experimental and other theoretical predictions wherever available. The values of the bulk viscosity have been found to be more than the corresponding values of the shear viscosity for all six thermodynamic states investigated here

  6. Nanopatterned Bulk Metallic Glass Biosensors.

    Science.gov (United States)

    Kinser, Emily R; Padmanabhan, Jagannath; Yu, Roy; Corona, Sydney L; Li, Jinyang; Vaddiraju, Sagar; Legassey, Allen; Loye, Ayomiposi; Balestrini, Jenna; Solly, Dawson A; Schroers, Jan; Taylor, André D; Papadimitrakopoulos, Fotios; Herzog, Raimund I; Kyriakides, Themis R

    2017-12-22

    Nanopatterning as a surface area enhancement method has the potential to increase signal and sensitivity of biosensors. Platinum-based bulk metallic glass (Pt-BMG) is a biocompatible material with electrical properties conducive for biosensor electrode applications, which can be processed in air at comparably low temperatures to produce nonrandom topography at the nanoscale. Work presented here employs nanopatterned Pt-BMG electrodes functionalized with glucose oxidase enzyme to explore the impact of nonrandom and highly reproducible nanoscale surface area enhancement on glucose biosensor performance. Electrochemical measurements including cyclic voltammetry (CV) and amperometric voltammetry (AV) were completed to compare the performance of 200 nm Pt-BMG electrodes vs Flat Pt-BMG control electrodes. Glucose dosing response was studied in a range of 2 mM to 10 mM. Effective current density dynamic range for the 200 nm Pt-BMG was 10-12 times greater than that of the Flat BMG control. Nanopatterned electrode sensitivity was measured to be 3.28 μA/cm 2 /mM, which was also an order of magnitude greater than the flat electrode. These results suggest that nonrandom nanotopography is a scalable and customizable engineering tool which can be integrated with Pt-BMGs to produce biocompatible biosensors with enhanced signal and sensitivity.

  7. Aspects of silicon bulk lifetimes

    Science.gov (United States)

    Landsberg, P. T.

    1985-01-01

    The best lifetimes attained for bulk crytalline silicon as a function of doping concentrations are analyzed. It is assumed that the dopants which set the Fermi level do not contribute to the recombination traffic which is due to the unknown defect. This defect is assumed to have two charge states: neutral and negative, the neutral defect concentration is frozen-in at some temperature T sub f. The higher doping concentrations should include the band-band Auger effect by using a generalization of the Shockley-Read-Hall (SRH) mechanism. The generalization of the SRH mechanism is discussed. This formulation gives a straightforward procedure for incorporating both band-band and band-trap Auger effects in the SRH procedure. Two related questions arise in this context: (1) it may sometimes be useful to write the steady-state occupation probability of the traps implied by SRH procedure in a form which approximates to the Fermi-Dirac distribution; and (2) the effect on the SRH mechanism of spreading N sub t levels at one energy uniformly over a range of energies is discussed.

  8. Plutonium assay calorimeters

    International Nuclear Information System (INIS)

    Perry, R.B.

    1978-01-01

    Three calorimeters were developed for the IAEA: a small-sample portable calorimeter, a bulk calorimeter for up to 2 kg Pu in cans and capable of measuring up to 25 watts, and a calorimeter for 4-m long LWR Pu-recycle fuel roads. Design parameters and performance capability are given, and the instruments are compared with those developed for NRC

  9. Solid phase assays

    International Nuclear Information System (INIS)

    Reese, M.G.; Johnson, L.R.; Ransom, D.K.

    1980-01-01

    In a solid phase assay for quantitative determination of biological and other analytes, a sample such as serum is contacted with a receptor for the analyte being assayed, the receptor being supported on a solid support. No tracer for the analyte is added to the sample before contacting with the receptor; instead the tracer is contacted with the receptor after unbound analyte has been removed from the receptor. The assay can be otherwise performed in a conventional manner but can give greater sensitivity. (author)

  10. Media Training

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    With the LHC starting up soon, the world's media are again turning their attention to CERN. We're all likely to be called upon to explain what is happening at CERN to media, friends and neighbours. The seminar will be given by BBC television news journalists Liz Pike and Nadia Marchant, and will deal with the kind of questions we're likely to be confronted with through the restart period. The training is open for everybody. Make sure you arrive early enough to get a seat - there are only 200 seats in the Globe. The session will also be webcast: http://webcast.cern.ch/

  11. Social Media Sites

    Science.gov (United States)

    Media Sites Site Registration Contact Us Search AF.mil: Home > AF Sites > Social Media Sites Social Media Welcome to the Air Force social media directory! The directory is a one-stop shop of official Air Force social media pages across various social media sites. Social media is all about

  12. PAME: plasmonic assay modeling environment

    Directory of Open Access Journals (Sweden)

    Adam Hughes

    2015-08-01

    Full Text Available Plasmonic assays are an important class of optical sensors that measure biomolecular interactions in real-time without the need for labeling agents, making them especially well-suited for clinical applications. Through the incorporation of nanoparticles and fiberoptics, these sensing systems have been successfully miniaturized and show great promise for in-situ probing and implantable devices, yet it remains challenging to derive meaningful, quantitative information from plasmonic responses. This is in part due to a lack of dedicated modeling tools, and therefore we introduce PAME, an open-source Python application for modeling plasmonic systems of bulk and nanoparticle-embedded metallic films. PAME combines aspects of thin-film solvers, nanomaterials and fiber-optics into an intuitive graphical interface. Some of PAME’s features include a simulation mode, a database of hundreds of materials, and an object-oriented framework for designing complex nanomaterials, such as a gold nanoparticles encased in a protein shell. An overview of PAME’s theory and design is presented, followed by example simulations of a fiberoptic refractometer, as well as protein binding to a multiplexed sensor composed of a mixed layer of gold and silver colloids. These results provide new insights into observed responses in reflectance biosensors.

  13. Factor IX assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003679.htm Factor IX assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  14. Factor VIII assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003678.htm Factor VIII assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  15. Factor II assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003674.htm Factor II assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  16. Factor VII assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003676.htm Factor VII assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  17. Microbead agglutination based assays

    KAUST Repository

    Kodzius, Rimantas; Castro, David; Foulds, Ian G.; Parameswaran, Ash M.; Sumanpreet, K. Chhina

    2013-01-01

    We report a simple and rapid room temperature assay for point-of-care (POC) testing that is based on specific agglutination. Agglutination tests are based on aggregation of microbeads in the presence of a specific analyte thus enabling

  18. Contrast media

    International Nuclear Information System (INIS)

    Decazes, Ph.

    2004-01-01

    The Guerbet firm, which holds 69% of the capital on the contrast media for medical imagery, could sale about 20% of this capital in order to accelerate its development in the United States, one of its next market with the Japan. (O.M.)

  19. Otitis media

    NARCIS (Netherlands)

    Rovers, MM; Schilder, AGM; Zielhuis, GA; Rosenfeld, RM

    2004-01-01

    Otitis media (OM) continues to be one of the most common childhood infections and is a major cause of morbidity in children. The pathogenesis of OM is multifactorial, involving the adaptive and native immune system, Eustachian-tube dysfunction, viral and bacterial load, and genetic and environmental

  20. Social Media

    Science.gov (United States)

    2010-05-01

    Digital Marketing and Ecommerce Professionals. 29 January 2010. 20 May 2010. <http://econsultancy.com/blog/5324-20+-mind-blowing-social- media...Statistics Revisited.” Econsultancy | Community of Digital Marketing and Ecommerce Professionals. 29 Jan. 2010. 20 May 2010. <http://econsultancy.com/blog

  1. Streaming Media

    Science.gov (United States)

    Pulley, John

    2009-01-01

    At a time when the evolutionary pace of new media resembles the real-time mutation of certain microorganisms, the age-old question of how best to connect with constituents can seem impossibly complex--even for an elite institution plugged into the motherboard of Silicon Valley. Identifying the most effective vehicle for reaching a particular…

  2. 27 CFR 20.191 - Bulk articles.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk articles. 20.191... Users of Specially Denatured Spirits Operations by Users § 20.191 Bulk articles. Users who convey articles in containers exceeding one gallon may provide the recipient with a photocopy of subpart G of this...

  3. On the bulk viscosity of relativistic matter

    International Nuclear Information System (INIS)

    Canuto, V.; Hsieh, S.-H.

    1978-01-01

    An expression for the bulk viscosity coefficient in terms of the trace of the hydrodynamic energy-stress tensor is derived from the Kubo formula. This, along with a field-theoretic model of an interacting system of scalar particles, suggests that at high temperatures the bulk viscosity tends to zero, contrary to the often quoted resuls of Iso, Mori and Namiki. (author)

  4. Bulk-viscosity-driven asymmetric inflationary universe

    International Nuclear Information System (INIS)

    Waga, I.; Lima, J.A.S.; Portugal, R.

    1987-01-01

    A primordial net bosinic charge is introduced in the context of the bulk-viscosity-driven inflationary models. The analysis is carried through a macroscopic point of view in the framework of the causal thermodynamic theory. The conditions for having exponetial and generalized inflation are obtained. A phenomenological expression for the bulk viscosity coefficient is also derived. (author) [pt

  5. [Chronic otitis mediaChronic Otitis Media].

    Science.gov (United States)

    Kohles, N; Schulz, T; Eßer, D

    2015-11-01

    There are 2 different kinds of chronic otitis media: Otitis media chronica mesotympanalis and otitis media chronica epitympanalis (cholesteatoma). The incidence of chronic otitis media as reported in literature differs in a wide range. The incidence rates vary between 0.45 and 46%. Both, otitis media chronica mesotympanalis and cholesteatoma, lead to eardrum perforation due to lengthy and recurring inflammations. Furthermore, chronic otitis media is characterized by frequently recurring otorrhea and conductive hearing loss. Georg Thieme Verlag KG Stuttgart · New York.

  6. Assay method and compositions

    International Nuclear Information System (INIS)

    1977-01-01

    Methods are described for measuring catecholamine levels in human and animal body fluids and tissues using the catechol-O-methyl-transferase (COMT) radioassay. The assay involves incubating the biological sample with COMT and the tritiated methyl donor, S-adenosyl-L-methionine( 3 H)-methyl. The O-methylated ( 3 H) epinephrine and/or norepinephrine are extracted and oxidised to vanillin- 3 H which in turn is extracted and its radioactivity counted. When analysing dopamine levels the assay is extended by vanillin- 3 H and raising the pH of the aqueous periodate phase from which O-methylated ( 3 H) dopamine is extracted and counted. The assay may be modified depending on whether measurements of undifferentiated total endogenous catecholamine levels or differential analyses of the catecholamine levels are being performed. The sensitivity of the assay can be as low as 5 picograms for norepinephrine and epinephrine and 12 picograms for dopamine. The assemblance of the essential components of the assay into a kit for use in laboratories is also described. (U.K.)

  7. On Media Education

    Science.gov (United States)

    Fedorov, Alexander

    2008-01-01

    This monograph analyzes the theory and practice of media education and media literacy. The book also includes the list of Russian media education literature and addresses of websites of the associations for media education.

  8. Performance of two resin-containing blood culture media in detection of bloodstream infections and in direct matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) broth assays for isolate identification: clinical comparison of the BacT/Alert Plus and Bactec Plus systems.

    Science.gov (United States)

    Fiori, Barbara; D'Inzeo, Tiziana; Di Florio, Viviana; De Maio, Flavio; De Angelis, Giulia; Giaquinto, Alessia; Campana, Lara; Tanzarella, Eloisa; Tumbarello, Mario; Antonelli, Massimo; Sanguinetti, Maurizio; Spanu, Teresa

    2014-10-01

    We compared the clinical performances of the BacT/Alert Plus (bioMérieux) and Bactec Plus (Becton Dickinson) aerobic and anaerobic blood culture (BC) media with adsorbent polymeric beads. Patients ≥ 16 years old with suspected bloodstream infections (BSIs) were enrolled in intensive care units and infectious disease wards. A single 40-ml blood sample was collected from each and used to inoculate (10 ml/bottle) one set of BacT/Alert Plus cultures and one set of Bactec Plus cultures, each set consisting of one aerobic and one anaerobic bottle. Cultures were incubated ≤ 5 days in the BacT/Alert 3D and Bactec FX instruments, respectively. A total of 128 unique BSI episodes were identified based on the recovery of clinically significant growth in 212 aerobic cultures (106 BacT/Alert and 106 Bactec) and 151 anaerobic cultures (82 BacT/Alert and 69 Bactec). The BacT/Alert aerobic medium had higher recovery rates for Gram-positive cocci (P = 0.024), whereas the Bactec aerobic medium was superior for recovery of Gram-negative bacilli (P = 0.006). BacT/Alert anaerobic medium recovery rates exceeded those of the Bactec anaerobic medium for total organisms (P = 0.003), Gram-positive cocci (P = 0.013), and Escherichia coli (P = 0.030). In terms of capacity for diagnosing the 128 septic episodes, the BacT/Alert and Bactec sets were comparable, although the former sets diagnosed more BSIs caused by Gram-positive cocci (P = 0.008). They also allowed earlier identification of coagulase-negative staphylococcal growth (mean, 2.8 h; P = 0.003) and growth in samples from patients not on antimicrobial therapy that yielded positive results (mean, 1.3 h; P direct matrix-assisted laser desorption ionization-time of flight mass spectrometry assay of BC broths. The BacT/Alert Plus media line appears to be a reliable, timesaving tool for routine detection of BSIs in the population we studied, although further studies are needed to evaluate their performance in other settings. Copyright

  9. Otitis media.

    Science.gov (United States)

    Schilder, Anne G M; Chonmaitree, Tasnee; Cripps, Allan W; Rosenfeld, Richard M; Casselbrant, Margaretha L; Haggard, Mark P; Venekamp, Roderick P

    2016-09-08

    Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis media (AOM), otitis media with effusion (OME; 'glue ear') and chronic suppurative otitis media (CSOM). OM is among the most common diseases in young children worldwide. Although OM may resolve spontaneously without complications, it can be associated with hearing loss and life-long sequelae. In developing countries, CSOM is a leading cause of hearing loss. OM can be of bacterial or viral origin; during 'colds', viruses can ascend through the Eustachian tube to the middle ear and pave the way for bacterial otopathogens that reside in the nasopharynx. Diagnosis depends on typical signs and symptoms, such as acute ear pain and bulging of the tympanic membrane (eardrum) for AOM and hearing loss for OME; diagnostic modalities include (pneumatic) otoscopy, tympanometry and audiometry. Symptomatic management of ear pain and fever is the mainstay of AOM treatment, reserving antibiotics for children with severe, persistent or recurrent infections. Management of OME largely consists of watchful waiting, with ventilation (tympanostomy) tubes primarily for children with chronic effusions and hearing loss, developmental delays or learning difficulties. The role of hearing aids to alleviate symptoms of hearing loss in the management of OME needs further study. Insertion of ventilation tubes and adenoidectomy are common operations for recurrent AOM to prevent recurrences, but their effectiveness is still debated. Despite reports of a decline in the incidence of OM over the past decade, attributed to the implementation of clinical guidelines that promote accurate diagnosis and judicious use of antibiotics and to pneumococcal conjugate vaccination, OM continues to be a leading cause for medical consultation, antibiotic prescription and surgery in high-income countries.

  10. Rover waste assay system

    Energy Technology Data Exchange (ETDEWEB)

    Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1997-11-01

    The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched {sup 235}U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for {sup 137}Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs.

  11. Rover waste assay system

    International Nuclear Information System (INIS)

    Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J.

    1997-01-01

    The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched 235 U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for 137 Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs

  12. Radioreceptor assay for insulin

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Kazuo [Tokyo Univ. (Japan). Faculty of Medicine

    1975-04-01

    Radioreceptor assay of insulin was discussed from the aspects of the measuring method, its merits and problems to be solved, and its clinical application. Rat liver 10 x g pellet was used as receptor site, and enzymatic degradation of insulin by the system contained in this fraction was inhibited by adding 1 mM p-CMB. /sup 125/I-labelled porcine insulin was made by lactoperoxidase method under overnight incubation at 4/sup 0/C and later purification by Sephadex G-25 column and Whatman CF-11 cellulose powder. Dog pancreatic vein serum insulin during and after the glucose load was determined by radioreceptor assay and radioimmunoassay resulting that both measurements accorded considerably. Radioreceptor assay would clarify the pathology of disorders of glucose metabolism including diabetes.

  13. Media matters.

    Science.gov (United States)

    Martinez, L M

    1995-01-01

    The impact of the mass media on woman's status was addressed at two 1995 conferences: the Fourth World Conference on Women, held in Beijing, China, and the Congress of the World Association for Christian Communication, held in Puebla, Mexico. The globalization process facilitated by the mass media has served to increase the power of patriarchy, with no advantages to the cause of women's rights. Coverage of popular movements has been suppressed out of deference to male-controlled governments. Coverage of the Beijing Conference highlighted celebrities and personal stories, to the exclusion of the economic and political issues under debate. Television has commodified women, reinforcing their oppression. On the other hand, the alternative media, which tend to be decentralized, democratic, low-cost, and low in technology, are presenting women as subjects rather than objects and deconstructing gender stereotypes. Of concern, however, is the tendency of computer technology to widen the gap between social classes and developed and developing countries. Women must use information networks to disseminate information on women's rights and strengthen the links between women throughout the world.

  14. Clonogenic assay: adherent cells.

    Science.gov (United States)

    Rafehi, Haloom; Orlowski, Christian; Georgiadis, George T; Ververis, Katherine; El-Osta, Assam; Karagiannis, Tom C

    2011-03-13

    The clonogenic (or colony forming) assay has been established for more than 50 years; the original paper describing the technique was published in 1956. Apart from documenting the method, the initial landmark study generated the first radiation-dose response curve for X-ray irradiated mammalian (HeLa) cells in culture. Basically, the clonogenic assay enables an assessment of the differences in reproductive viability (capacity of cells to produce progeny; i.e. a single cell to form a colony of 50 or more cells) between control untreated cells and cells that have undergone various treatments such as exposure to ionising radiation, various chemical compounds (e.g. cytotoxic agents) or in other cases genetic manipulation. The assay has become the most widely accepted technique in radiation biology and has been widely used for evaluating the radiation sensitivity of different cell lines. Further, the clonogenic assay is commonly used for monitoring the efficacy of radiation modifying compounds and for determining the effects of cytotoxic agents and other anti-cancer therapeutics on colony forming ability, in different cell lines. A typical clonogenic survival experiment using adherent cells lines involves three distinct components, 1) treatment of the cell monolayer in tissue culture flasks, 2) preparation of single cell suspensions and plating an appropriate number of cells in petri dishes and 3) fixing and staining colonies following a relevant incubation period, which could range from 1-3 weeks, depending on the cell line. Here we demonstrate the general procedure for performing the clonogenic assay with adherent cell lines with the use of an immortalized human keratinocyte cell line (FEP-1811). Also, our aims are to describe common features of clonogenic assays including calculation of the plating efficiency and survival fractions after exposure of cells to radiation, and to exemplify modification of radiation-response with the use of a natural antioxidant

  15. Bulk viscosity in holographic Lifshitz hydrodynamics

    International Nuclear Information System (INIS)

    Hoyos, Carlos; Kim, Bom Soo; Oz, Yaron

    2014-01-01

    We compute the bulk viscosity in holographic models dual to theories with Lifshitz scaling and/or hyperscaling violation, using a generalization of the bulk viscosity formula derived in arXiv:1103.1657 from the null focusing equation. We find that only a class of models with massive vector fields are truly Lifshitz scale invariant, and have a vanishing bulk viscosity. For other holographic models with scalars and/or massless vector fields we find a universal formula in terms of the dynamical exponent and the hyperscaling violation exponent

  16. Scintillation proximity assay

    International Nuclear Information System (INIS)

    Hart, H.

    1980-01-01

    In a method of immunological assay two different classes of particles which interact at short distances to produce characteristic detectable signals are employed in a modification of the usual latex fixation test. In one embodiment an aqueous suspension of antigen coated tritiated latex particles (LH) and antigen coated polystyrene scintillant particles (L*) is employed to assay antibody in the aqueous medium. The amount of (LH) (L*) dimer formation and higher order aggregation induced and therefore the concentration of antibody (or antigen) present which caused the aggregation can be determined by using standard liquid scintillation counting equipment. (author)

  17. Assays for calcitonin receptors

    International Nuclear Information System (INIS)

    Teitelbaum, A.P.; Nissenson, R.A.; Arnaud, C.D.

    1985-01-01

    The assays for calcitonin receptors described focus on their use in the study of the well-established target organs for calcitonin, bone and kidney. The radioligand used in virtually all calcitonin binding studies is 125 I-labelled salmon calcitonin. The lack of methionine residues in this peptide permits the use of chloramine-T for the iodination reaction. Binding assays are described for intact bone, skeletal plasma membranes, renal plasma membranes, and primary kidney cell cultures of rats. Studies on calcitonin metabolism in laboratory animals and regulation of calcitonin receptors are reviewed

  18. Media Education Initiatives by Media Organizations: The Uses of Media Literacy in Hong Kong Media

    Science.gov (United States)

    Chu, Donna; Lee, Alice Y. L.

    2014-01-01

    As more media organizations have engaged in media education, this paper investigates the goals and practices of these activities. This article coins media education initiatives by media organizations with the term "media-organization media literac"y (MOML). Four MOML projects in Hong Kong were selected for examination. Built on critical…

  19. Optical bulk and surface waves with negative refraction

    International Nuclear Information System (INIS)

    Agranovich, V.M.; Shen, Y.R.; Baughman, R.H.; Zakhidov, A.A.

    2004-01-01

    In materials with negative refraction, the direction of wave propagation is opposite to the direction of the wave vector. Using an approach that characterizes the optical response of a medium totally by a generalized dielectric permittivity, ε-bar (ω,k-bar), we discuss the possibility of seeing negative refraction for optical waves in a number of nonmagnetic media. These include bulk waves in organic materials and in gyrotropic materials where additional exciton-polariton waves can have a negative group velocity. It is known that dispersion of surface waves can be engineered by tailoring a surface transition layer. We show how this effect can be used to obtain surface waves with negative refraction

  20. Bulk Leisure--Problem or Blessing?

    Science.gov (United States)

    Beland, Robert M.

    1983-01-01

    With an increasing number of the nation's work force experiencing "bulk leisure" time because of new work scheduling procedures, parks and recreation offices are encouraged to examine their program scheduling and content. (JM)

  1. Technical specifications for the bulk shielding reactor

    International Nuclear Information System (INIS)

    1986-05-01

    This report provides information concerning the technical specifications for the Bulk Shielding Reactor. Areas covered include: safety limits and limiting safety settings; limiting conditions for operation; surveillance requirements; design features; administrative controls; and monitoring of airborne effluents. 10 refs

  2. Lateral flow assays

    NARCIS (Netherlands)

    Posthuma-Trumpie, G.A.; Amerongen, van A.

    2012-01-01

    A simple version of immunochemical-based methods is the Lateral Flow Assay (LFA). It is a dry chemistry technique (reagents are included); the fluid from the sample runs through a porous membrane (often nitrocellulose) by capillary force. Typically the membrane is cut as a strip of 0.5*5 cm. In most

  3. Microchemiluminescent assay system

    Energy Technology Data Exchange (ETDEWEB)

    Kiel, J.L.

    1986-04-09

    The patent concerns a microchemiluminescent assay system, which can be used to detect ionizing radiation, heat or specific substances. The method involves the use of a complex formed from serum albumin and a luminescer which, in the presence of ionizing radiation (heat, or a specific analyte), will emit light in an amount proportional to the amount of radiation, etc. (U.K.).

  4. (MTT) dye reduction assay.

    African Journals Online (AJOL)

    to inhibit proliferation of HeLa cells was determined using the 3443- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) dye reduction assay. Extracts from roots of Agathisanthemum bojeri, Synaptolepis kirkii and Zanha africana and the leaf extract of Physalis peruviana at a concentration of 10 pg/ml inhibited cell ...

  5. Hyaluronic Acid Assays

    DEFF Research Database (Denmark)

    Itenov, Theis S; Kirkby, Nikolai S; Bestle, Morten H

    2015-01-01

    BACKGROUD: Hyaluronic acid (HA) is proposed as a marker of functional liver capacity. The aim of the present study was to compare a new turbidimetric assay for measuring HA with the current standard method. METHODS: HA was measured by a particle-enhanced turbidimetric immunoassay (PETIA) and enzyme...

  6. FLUIDICS DEVICE FOR ASSAY

    DEFF Research Database (Denmark)

    2007-01-01

    The present invention relates to a device for use in performing assays on standard laboratory solid supports whereon chemical entities are attached. The invention furthermore relates to the use of such a device and a kit comprising such a device. The device according to the present invention is a...

  7. Force measurements for levitated bulk superconductors

    International Nuclear Information System (INIS)

    Tachi, Y.; Sawa, K.; Iwasa, Y.; Nagashima, K.; Otani, T.; Miyamoto, T.; Tomita, M.; Murakami, M.

    2000-01-01

    We have developed a force measurement system which enables us to directly measure the levitation force of levitated bulk superconductors. Experimental data of the levitation forces were compared with the results of numerical simulation based on the levitation model that we deduced in our previous paper. They were in fairly good agreement, which confirms that our levitation model can be applied to the force analyses for levitated bulk superconductors. (author)

  8. Force measurements for levitated bulk superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Tachi, Y. [Department of Electrical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama (Japan); ISTEC, Superconductivity Research Laboratory, 1-16-25 Shibaura, Minato-ku, Tokyo (Japan). E-mail: tachi at istec.or.jp; Uemura, N. [Department of Electrical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama (Japan); ISTEC, Superconductivity Research Laboratory, 1-16-25 Shibaura, Minato-ku, Tokyo (Japan); Sawa, K. [Department of Electrical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama (Japan); Iwasa, Y. [Francis Bitter Magnet Laboratory, Massachusetts Institute of Technology, Cambridge, MA (United States); Nagashima, K. [Railway Technical Research Institute, Hikari-cho, Kokubunji-shi, Tokyo (Japan); Otani, T.; Miyamoto, T.; Tomita, M.; Murakami, M. [ISTEC, Superconductivity Research Laboratory, 1-16-25 Shibaura, Minato-ku, Tokyo (Japan)

    2000-06-01

    We have developed a force measurement system which enables us to directly measure the levitation force of levitated bulk superconductors. Experimental data of the levitation forces were compared with the results of numerical simulation based on the levitation model that we deduced in our previous paper. They were in fairly good agreement, which confirms that our levitation model can be applied to the force analyses for levitated bulk superconductors. (author)

  9. ANALISIS KESELAMATAN TERMOHIDROLIK BULK SHIELDING REAKTOR KARTINI

    Directory of Open Access Journals (Sweden)

    Azizul Khakim

    2015-10-01

    Full Text Available ABSTRAK ANALISIS KESELAMATAN TERMOHIDROLIK BULK SHIELDING REAKTOR KARTINI. Bulk shielding merupakan fasilitas yang terintegrasi dengan reaktor Kartini yang berfungsi sebagai penyimpanan sementara bahan bakar bekas. Fasilitas ini merupakan fasilitas yang termasuk dalam struktur, sistem dan komponen (SSK yang penting bagi keselamatan. Salah satu fungsi keselamatan dari sistem penanganan dan penyimpanan bahan bakar adalah mencegah kecelakaan kekritisan yang tak terkendali dan membatasi naiknya temperatur bahan bakar. Analisis keselamatan paling kurang harus mencakup analisis keselamatan dari sisi neutronik dan termo hidrolik Bulk shielding. Analisis termo hidrolik ditujukan untuk memastikan perpindahan panas dan proses pendinginan bahan bakar bekas berjalan baik dan tidak terjadi akumulasi panas yang mengancam integritas bahan bakar. Code tervalidasi PARET/ANL digunakan untuk analisis pendinginan dengan mode konveksi alam. Hasil perhitungan menunjukkan bahwa mode pendinginan konvekasi alam cukup memadai dalam mendinginkan panas sisa tanpa mengakibatkan kenaikan temperatur bahan bakar yang signifikan. Kata kunci: Bulk shielding, bahan bakar bekas, konveksi alam, PARET.   ABSTRACT THERMAL HYDRAULIC SAFETY ANALYSIS OF BULK SHIELDING KARTINI REACTOR. Bulk shielding is an integrated facility to Kartini reactor which is used for temporary spent fuels storage. The facility is one of the structures, systems and components (SSCs important to safety. Among the safety functions of fuel handling and storage are to prevent any uncontrolable criticality accidents and to limit the fuel temperature increase. Safety analyses should, at least, cover neutronic and thermal hydraulic calculations of the bulk shielding. Thermal hydraulic analyses were intended to ensure that heat removal and the process of the spent fuels cooling takes place adequately and no heat accumulation that challenges the fuel integrity. Validated code, PARET/ANL was used for analysing the

  10. Radioisotopic 51Cr-leukocyte adherence inhibition (LAI) assay. I

    International Nuclear Information System (INIS)

    Tsang, P.H.; Tangnavarad, K.; Lesnick, G.; Holland, J.F.; Bekesi, J.G.; Perloff, M.

    1980-01-01

    A simplified radioisotopic leukocyte adherence inhibition assay ( 51 Cr-LAI assay) was used to determine tumor-directed immune responses in patients with cancer of the breast. Essential steps in development of this assay are the standardization of conditions for optimal 51 Cr uptake by peripheral blood lymphocytes (PBL) and the inclusion of autologous or normal AB serum in the incubation media. A dextrose salt mixture (GNK) was found to enhance intracellular uptake of 51 Cr significantly (8-fold) without affecting viability of the cells or without causing selective loss of lymphocyte subpopulations. The presence of 10% autologous or normal AB serum prevented non-specific LAI responses to unrelated tumor antigens. Experimental results are presented and it is seen that this short term (4 h) 51 Cr-LAI assay provides reproducible and specific results analogous to those using tube-LAI assay. The test has the advantages of being accurate, sensitive and free from technical bias. (Auth.)

  11. Media Matter

    Directory of Open Access Journals (Sweden)

    Holger Pötzsch

    2017-02-01

    Full Text Available The present contribution maps materialist advances in media studies. Based on the assumption that matter and materiality constitute significant aspects of communication processes and practices, I introduce four fields of inquiry - technology, political economy, ecology, and the body - and argue that these perspectives enable a more comprehensive understanding of the implications of contemporary technologically afforded forms of interaction. The article shows how each perspective can balance apologetic and apocalyptic approaches to the impact of in particular digital technologies, before it demonstrates the applicability of an integrated framework with reference to the techno-politics of NSA surveillance and the counter-practices of WikiLeaks.

  12. Media education and media influence on youth

    OpenAIRE

    LILÁK, Karel

    2011-01-01

    Bachelor´s work is focused on the questions of the medial education and the medias themselves. This work also investigate with the influence of the action of medias to the students of apprenticeship. The first part of the theoretical work has generally explains what is media education, what is its significance for society and for the benefit of education in school. They are given functions, types and objectives of media education and communications capabilities via the media. The second part ...

  13. Standardization of portable assay instrumentation: the neutron-coincidence tree

    International Nuclear Information System (INIS)

    Menlove, H.O.

    1983-01-01

    Standardization of portable neutron assay instrumentation has been achieved by using the neutron coincidence technique as a common basis for a wide range of instruments and applications. The electronics originally developed for the High-Level Neutron Coincidence Counter has been adapted to both passive- and active-assay instrumentation for field verification of bulk plutonium, inventory samples, pellets, powders, nitrates, high-enriched uranium, and materials-testing-reactor, light-water-reactor, and mixed-oxide fuel assemblies. The family of detectors developed at Los Alamos National Laboratory and their performance under in-field conditions are described. 16 figures, 3 tables

  14. Dynamic crack propagation through nanoporous media

    Science.gov (United States)

    Nguyen, Thao; Wilkerson, Justin

    2015-06-01

    The deformation and failure of nanoporous metals may be considerably different than that of more traditional bulk porous metals. The length scales in traditional bulk porous metals are typically large enough for classic plasticity and buckling to be operative. However, the extremely small length scales associated with nanoporous metals may inhibit classic plasticity mechanisms. Here, we motivate an alternative nanovoid growth mechanism mediated by dislocation emission. Following an approach similar to Lubarda and co-workers, we make use of stability arguments applied to the analytic solutions of the elastic interactions of dislocations and voids to derive a simple stress-based criterion for emission activation. We then propose a dynamic nanovoid growth law that is motivated by the kinetics of dislocation emission. The resulting failure model is implemented into a commercial finite element software to simulate dynamic crack growth. The simulations reveal that crack propagation through a nanoporous media proceeds at somewhat faster velocities than through the more traditional bulk porous metal.

  15. Radioreceptor assay for oxyphenonium

    International Nuclear Information System (INIS)

    Ensing, K.; Zeeuw, R.A. de

    1984-01-01

    The development of a radioreceptor assay for the quaternary anticholinergic drug, oxyphenonium, in plasma is reported. It is based on competition between this drug and 3 H-dexetimide for binding to muscarinic receptors. After ion pair extraction and reextraction, the drug can be determined in plasma at concentrations down to a value of 100 pg/ml. This permits pharmacokinetic studies to be made after inhalation of oxyphenonium. (author)

  16. Dual isotope assays

    International Nuclear Information System (INIS)

    Smith, G.F.W.; Stevens, R.A.J.; Jacoby, B.

    1980-01-01

    Dual isotope assays for thyroid function are performed by carrying out a radio-immunoassay for two of thyroxine (T4), tri-iodothyronine (T3), thyroid stimulating hormone (TSH), and thyroxine binding globulin (TBG), by a method wherein a version of one of the thyroid components, preferably T4 or T3 is labelled with Selenium-75 and the version of the other thyroid component is labelled with a different radionuclide, preferably Iodine-125. (author)

  17. High resolution gamma-ray spectroscopy applied to bulk sample analysis

    International Nuclear Information System (INIS)

    Kosanke, K.L.; Koch, C.D.; Wilson, R.D.

    1980-01-01

    A high resolution Ge(Li) gamma-ray spectrometer has been installed and made operational for use in routine bulk sample analysis by the Bendix Field Engineering Corporation (BFEC) geochemical analysis department. The Ge(Li) spectrometer provides bulk sample analyses for potassium, uranium, and thorium that are superior to those obtained by the BFEC sodium iodide spectrometer. The near term analysis scheme permits a direct assay for uranium that corrects for bulk sample self-absorption effects and is independent of the uranium/radium disequilibrium condition of the sample. A more complete analysis scheme has been developed that fully utilizes the gamma-ray data provided by the Ge(Li) spectrometer and that more properly accounts for the sample self-absorption effect. This new analysis scheme should be implemented on the BFEC Ge(Li) spectrometer at the earliest date

  18. Managing Media: Segmenting Media Through Consumer Expectancies

    Directory of Open Access Journals (Sweden)

    Matt Eastin

    2014-04-01

    Full Text Available It has long been understood that consumers are motivated to media differently. However, given the lack of comparative model analysis, this assumption is without empirical validation, and thus, the orientation of segmentation from a media management perspective is without motivational grounds. Thus, evolving the literature on media consumption, the current study develops and compares models of media segmentation within the context of use. From this study, six models of media expectancies were constructed so that motivational differences between media (i.e., local and national newspapers, network and cable television, radio, and Internet could be observed. Utilizing higher order statistical analyses the data indicates differences across a model comparison approach for media motivations. Furthermore, these differences vary across numerous demographic factors. Results afford theoretical advancement within the literature of consumer media consumption as well as provide media planners’ insight into consumer choices.

  19. Development of superconductor bulk for superconductor bearing

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Joong; Jun, Byung Hyuk; Park, Soon Dong (and others)

    2008-08-15

    Current carrying capacity is one of the most important issues in the consideration of superconductor bulk materials for engineering applications. There are numerous applications of Y-Ba-Cu-O (YBCO) bulk superconductors e.g. magnetic levitation train, flywheel energy storage system, levitation transportation, lunar telescope, centrifugal device, magnetic shielding materials, bulk magnets etc. Accordingly, to obtain YBCO materials in the form of large, single crystals without weak-link problem is necessary. A top seeded melt growth (TSMG) process was used to fabricate single crystal YBCO bulk superconductors. The seeded and infiltration growth (IG) technique was also very promising method for the synthesis of large, single-grain YBCO bulk superconductors with good superconducting properties. 5 wt.% Ag doped Y211 green compacts were sintered at 900 .deg. C {approx} 1200 .deg.C and then a single crystal YBCO was fabricated by an infiltration method. A refinement and uniform distribution of the Y211 particles in the Y123 matrix were achieved by sintering the Ag-doped samples. This enhancement of the critical current density was ascribable to a fine dispersion of the Y211 particles, a low porosity and the presence of Ag particles. In addition, we have designed and manufactured large YBCO single domain with levitation force of 10-13 kg/cm{sup 2} using TSMG processing technique.

  20. Module 13: Bulk Packaging Shipments by Highway

    International Nuclear Information System (INIS)

    Przybylski, J.L.

    1994-07-01

    The Hazardous Materials Modular Training Program provides participating United States Department of Energy (DOE) sites with a basic, yet comprehensive, hazardous materials transportation training program for use onsite. This program may be used to assist individual program entities to satisfy the general awareness, safety training, and function specific training requirements addressed in Code of Federal Regulation (CFR), Title 49, Part 172, Subpart H -- ''Training.'' Module 13 -- Bulk Packaging Shipments by Highway is a supplement to the Basic Hazardous Materials Workshop. Module 13 -- Bulk Packaging Shipments by Highway focuses on bulk shipments of hazardous materials by highway mode, which have additional or unique requirements beyond those addressed in the ten module core program. Attendance in this course of instruction should be limited to those individuals with work experience in transporting hazardous materials utilizing bulk packagings and who have completed the Basic Hazardous Materials Workshop or an equivalent. Participants will become familiar with the rules and regulations governing the transportation by highway of hazardous materials in bulk packagings and will demonstrate the application of these requirements through work projects and examination

  1. A comparative study of bulk-fill composites: degree of conversion, post-gel shrinkage and cytotoxicity

    Directory of Open Access Journals (Sweden)

    Flávia Gonçalves

    2018-03-01

    Full Text Available Abstract: Bulk-fill composites are claimed to be restorative materials used in deep preparations and effectively photoactivated in layers up to 4 mm. The aim of the present study was to evaluate the degree of conversion, post-gel volumetric shrinkage, and cytotoxicity of six bulk-fill and two conventional composites. Degree of conversion was determined by FTIR spectroscopy; post-gel volumetric shrinkage was determined using the strain gauge method; and cytotoxicity in human fibroblasts was evaluated indirectly by the MTT assay. Data were subjected to one-way ANOVA/Tukey's test (α = 0.05. All materials, including bulk-fill and conventional composites, were classified as non-toxic, with cell viability higher than 70%. Bulk-fill composites exhibited volumetric shrinkage similar to or lower (1.4 to 0.4% than that of conventional composites (1.7–2.1%. However, only four of the bulk-fill composites were able to sustain a homogeneous conversion at the 4-mm depth. Despite their non-toxicity and shrinkage similar to that of conventional materials, not all commercial bulk-fill materials were able to maintain a conversion as high as 80% of the superficial layer, at the 4-mm depth, indicating some failure in the bulk-fill design of some commercial brands. Therefore, the use of bulk-fill materials in dental practice is advantageous, but special attention should be given to the selection and correct use of the materials.

  2. Geographic Media Literacy

    Science.gov (United States)

    Lukinbeal, Chris

    2014-01-01

    While the use of media permeates geographic research and pedagogic practice, the underlying literacies that link geography and media remain uncharted. This article argues that geographic media literacy incorporates visual literacy, information technology literacy, information literacy, and media literacy. Geographic media literacy is the ability…

  3. Adolescents and media literacy.

    Science.gov (United States)

    McCannon, Robert

    2005-06-01

    In the face of media industry consolidation, fewer people control media content which makes it harder for parents and citizens to know the research about media-related issues, such as video game violence, nutrition, and sexual risk-taking. Media literacy offers a popular and potentially successful way to counter the misinformation that is spread by Big Media public relations.

  4. Safety in online media – freedom of the media; safety of media actors and media education

    OpenAIRE

    Moeller, Ch

    2013-01-01

    In this paper, prepared for the international conference ‘Mass Media – Society – Education: Media Safety Problems’ at the Chelyabinsk State University’s Department for Journalism and Media Education from September 30 – October 3, 2013, I would like to address three dimensions of media safety and security in online media.

  5. SOCIAL MEDIA SECURITY

    Science.gov (United States)

    RESPONSIBILITY CENTCOM COALITION MEDIA SOCIAL MEDIA NEWS ARTICLES PRESS RELEASES IMAGERY VIDEOS TRANSCRIPTS VISITORS AND PERSONNEL FAMILY CENTER FAMILY READINESS CENTCOM WEBMAIL SOCIAL MEDIA SECURITY ACCOUNTABILITY HomeVISITORS AND PERSONNELSOCIAL MEDIA SECURITY FAQ on Security for Social Media Due to the widespread use of

  6. Measuring News Media Literacy

    Science.gov (United States)

    Maksl, Adam; Ashley, Seth; Craft, Stephanie

    2015-01-01

    News media literacy refers to the knowledge and motivations needed to identify and engage with journalism. This study measured levels of news media literacy among 500 teenagers using a new scale measure based on Potter's model of media literacy and adapted to news media specifically. The adapted model posits that news media literate individuals…

  7. Bulk-memory processor for data acquisition

    International Nuclear Information System (INIS)

    Nelson, R.O.; McMillan, D.E.; Sunier, J.W.; Meier, M.; Poore, R.V.

    1981-01-01

    To meet the diverse needs and data rate requirements at the Van de Graaff and Weapons Neutron Research (WNR) facilities, a bulk memory system has been implemented which includes a fast and flexible processor. This bulk memory processor (BMP) utilizes bit slice and microcode techniques and features a 24 bit wide internal architecture allowing direct addressing of up to 16 megawords of memory and histogramming up to 16 million counts per channel without overflow. The BMP is interfaced to the MOSTEK MK 8000 bulk memory system and to the standard MODCOMP computer I/O bus. Coding for the BMP both at the microcode level and with macro instructions is supported. The generalized data acquisition system has been extended to support the BMP in a manner transparent to the user

  8. Micro benchtop optics by bulk silicon micromachining

    Science.gov (United States)

    Lee, Abraham P.; Pocha, Michael D.; McConaghy, Charles F.; Deri, Robert J.

    2000-01-01

    Micromachining of bulk silicon utilizing the parallel etching characteristics of bulk silicon and integrating the parallel etch planes of silicon with silicon wafer bonding and impurity doping, enables the fabrication of on-chip optics with in situ aligned etched grooves for optical fibers, micro-lenses, photodiodes, and laser diodes. Other optical components that can be microfabricated and integrated include semi-transparent beam splitters, micro-optical scanners, pinholes, optical gratings, micro-optical filters, etc. Micromachining of bulk silicon utilizing the parallel etching characteristics thereof can be utilized to develop miniaturization of bio-instrumentation such as wavelength monitoring by fluorescence spectrometers, and other miniaturized optical systems such as Fabry-Perot interferometry for filtering of wavelengths, tunable cavity lasers, micro-holography modules, and wavelength splitters for optical communication systems.

  9. Holographic bulk reconstruction with α' corrections

    Science.gov (United States)

    Roy, Shubho R.; Sarkar, Debajyoti

    2017-10-01

    We outline a holographic recipe to reconstruct α' corrections to anti-de Sitter (AdS) (quantum) gravity from an underlying CFT in the strictly planar limit (N →∞ ). Assuming that the boundary CFT can be solved in principle to all orders of the 't Hooft coupling λ , for scalar primary operators, the λ-1 expansion of the conformal dimensions can be mapped to higher curvature corrections of the dual bulk scalar field action. Furthermore, for the metric perturbations in the bulk, the AdS /CFT operator-field isomorphism forces these corrections to be of the Lovelock type. We demonstrate this by reconstructing the coefficient of the leading Lovelock correction, also known as the Gauss-Bonnet term in a bulk AdS gravity action using the expression of stress-tensor two-point function up to subleading order in λ-1.

  10. Media Literacy in Times of Media Divides

    Directory of Open Access Journals (Sweden)

    Kaja Žuran

    2013-12-01

    Full Text Available We live in a post-modern society, an information society, a society based around knowledge and participation, and above all in a media society. In a media culture where media holds a dominant position, we cannot overlook the emerging idea of a ‘media divide’ within the frame of media education, media literate individuals and the expansion of the traditional concept of media literacy. Firstly, we are in an era of technological revolution, and it is time to consider the meaning and function of media and how we experience it in our everyday life. Secondly, as a society we are subject to intense media invasion and we all need to learn how to use it to our benefit and apply a critical and autonomous perspective towards selecting media content. Otherwise the media divide between the media literate and illiterate will widen; but is there even a chance to overcome the supposed divide between those who are formally media educated and those who are not?

  11. Big bang nucleosynthesis constraints on bulk neutrinos

    International Nuclear Information System (INIS)

    Goh, H.S.; Mohapatra, R.N.

    2002-01-01

    We examine the constraints imposed by the requirement of successful nucleosynthesis on models with one large extra hidden space dimension and a single bulk neutrino residing in this dimension. We solve the Boltzmann kinetic equation for the thermal distribution of the Kaluza-Klein modes and evaluate their contribution to the energy density at the big bang nucleosynthesis epoch to constrain the size of the extra dimension R -1 ≡μ and the parameter sin 2 2θ which characterizes the mixing between the active and bulk neutrinos

  12. Synthesis of Bulk Superconducting Magnesium Diboride

    Directory of Open Access Journals (Sweden)

    Margie Olbinado

    2002-06-01

    Full Text Available Bulk polycrystalline superconducting magnesium diboride, MgB2, samples were successfully prepared via a one-step sintering program at 750°C, in pre Argon with a pressure of 1atm. Both electrical resistivity and magnetic susceptibility measurements confirmed the superconductivity of the material at 39K, with a transition width of 5K. The polycrystalline nature, granular morphology, and composition of the sintered bulk material were confirmed using X-ray diffractometry (XRD, scanning electron microscopy (SEM, and energy dispersive X-ray analysis (EDX.

  13. Radiation-hardened bulk CMOS technology

    International Nuclear Information System (INIS)

    Dawes, W.R. Jr.; Habing, D.H.

    1979-01-01

    The evolutionary development of a radiation-hardened bulk CMOS technology is reviewed. The metal gate hardened CMOS status is summarized, including both radiation and reliability data. The development of a radiation-hardened bulk silicon gate process which was successfully implemented to a commercial microprocessor family and applied to a new, radiation-hardened, LSI standard cell family is also discussed. The cell family is reviewed and preliminary characterization data is presented. Finally, a brief comparison of the various radiation-hardened technologies with regard to performance, reliability, and availability is made

  14. Radiorespirometic assay device

    International Nuclear Information System (INIS)

    Levin, G.V.; Straat, P.A.

    1981-01-01

    A radiorespirometic assay device is described in which the presence of microorganisms in a sample is determined by placing the sample in contact with a metabolisable radioactive labelled substrate, collecting any gas evolved, exposing a photosensitive material to the gas and determining if a spot is produced on the material. A spot indicates the presence of radioactivity showing that the substrate has been metabolized by a microorganism. Bacteria may be detected in body fluids, hospital operating rooms, water, food, cosmetics and drugs. (U.K.)

  15. Radon assay for SNO+

    Energy Technology Data Exchange (ETDEWEB)

    Rumleskie, Janet [Laurentian University, Greater Sudbury, Ontario (Canada)

    2015-12-31

    The SNO+ experiment will study neutrinos while located 6,800 feet below the surface of the earth at SNOLAB. Though shielded from surface backgrounds, emanation of radon radioisotopes from the surrounding rock leads to back-grounds. The characteristic decay of radon and its daughters allows for an alpha detection technique to count the amount of Rn-222 atoms collected. Traps can collect Rn-222 from various positions and materials, including an assay skid that will collect Rn-222 from the organic liquid scintillator used to detect interactions within SNO+.

  16. Otitis media with effusion

    Science.gov (United States)

    OME; Secretory otitis media; Serous otitis media; Silent otitis media; Silent ear infection; Glue ear ... from the tube and is swallowed. OME and ear infections are connected in two ways: After most ear ...

  17. Intermediality and media change

    OpenAIRE

    2012-01-01

    This book is about intermediality as an approach to analysing and understanding media change. Intermediality and Media Change is critical of technological determinism that characterises 'new media discourse' about the ongoing digitalization, framed as a revolution and creating sharp contrasts between old and new media. Intermediality instead emphasises paying attention to continuities between media of all types and privileges a comparative perspective on technological changes in media over ti...

  18. Media Pembelajaran Global Warming

    OpenAIRE

    Tham, Fikri Jufri; Liliana, Liliana; Purba, Kristo Radion

    2016-01-01

    Computer based learning media is one of the media has an important role in learning. Learning media will be attractive when packaged through interactive media , such as interactive media created in paper manufacture " instructional media global warming" . The advantage gained is that it can increase knowledge, generally educate people to be more concerned about the environment , and also can be a means of entertainment. This application is focused to learn about global warming and packaged in...

  19. RAS - Screens & Assays - Drug Discovery

    Science.gov (United States)

    The RAS Drug Discovery group aims to develop assays that will reveal aspects of RAS biology upon which cancer cells depend. Successful assay formats are made available for high-throughput screening programs to yield potentially effective drug compounds.

  20. Study of methods for the improvement of bacterial transport media

    Science.gov (United States)

    Gardner, R. L.; Beakley, J. W.

    1973-01-01

    A series of 500 transport media recipes was tested for ability to hold pure cultures of Streptococcus equisimilus, Corynebacterium equi, Neisseria perflava, and Haemophilus parainfluenzae for 21 days. Stuart Medium Base with 0.4% agar was used as the control medium for this and the other experiments in the investigation. At the end of the holding period inoculated transport media were quantitatively assayed, and the control media were assayed immediately after inoculation. Three vials of each medium were inoculated with an organism, and each vial's medium was diluted and spread on duplicate plates. Assay media for this experiment included Brain Heart Infusion,(BHIA) Tryptic Soy Agar, and BHIA with 1% Isovitalex enrichment.

  1. Improving shuffler assay accuracy

    International Nuclear Information System (INIS)

    Rinard, P.M.

    1995-01-01

    Drums of uranium waste should be disposed of in an economical and environmentally sound manner. The most accurate possible assays of the uranium masses in the drums are required for proper disposal. The accuracies of assays from a shuffler are affected by the type of matrix material in the drums. Non-hydrogenous matrices have little effect on neutron transport and accuracies are very good. If self-shielding is known to be a minor problem, good accuracies are also obtained with hydrogenous matrices when a polyethylene sleeve is placed around the drums. But for those cases where self-shielding may be a problem, matrices are hydrogenous, and uranium distributions are non-uniform throughout the drums, the accuracies are degraded. They can be greatly improved by determining the distributions of the uranium and then applying correction factors based on the distributions. This paper describes a technique for determining uranium distributions by using the neutron count rates in detector banks around the waste drum and solving a set of overdetermined linear equations. Other approaches were studied to determine the distributions and are described briefly. Implementation of this correction is anticipated on an existing shuffler next year

  2. Competitive protein binding assay

    International Nuclear Information System (INIS)

    Kaneko, Toshio; Oka, Hiroshi

    1975-01-01

    The measurement of cyclic GMP (cGMP) by competitive protein binding assay was described and discussed. The principle of binding assay was represented briefly. Procedures of our method by binding protein consisted of preparation of cGMP binding protein, selection of 3 H-cyclic GMP on market, and measurement procedures. In our method, binding protein was isolated from the chrysalis of silk worm. This method was discussed from the points of incubation medium, specificity of binding protein, the separation of bound cGMP from free cGMP, and treatment of tissue from which cGMP was extracted. cGMP existing in the tissue was only one tenth or one scores of cGMP, and in addition, cGMP competed with cGMP in binding with binding protein. Therefore, Murad's technique was applied to the isolation of cGMP. This method provided the measurement with sufficient accuracy; the contamination by cAMP was within several per cent. (Kanao, N.)

  3. Social media management and media environment

    Directory of Open Access Journals (Sweden)

    Šiđanin Iva

    2012-01-01

    Full Text Available The paper deals with the system of services that social media management can offer to a variety of users. As social media systems are emerging, social media management can strengthen teams in social media and help to manage numerous social channels and distribution of social information from one place. Social media management is a system of procedures that are used to manage the flow of information in the environment of social media. This involves connecting with social media like Facebook, Twitter, LinkedIn, Plaxo, Ecademy, YouTube and many others, then the aggregation and management of social data. Social media management services are analysed through various fields, such as managing multiple social media profiles, mail scheduling and filtering, reporting and analytics. Social media management enables managing personal business through social media, which contributes to a significant reduction in expenditures. The paper also discusses the importance of social media management in marketing activities and various forms of social promotion, which allow companies to easily reach their customers.

  4. 46 CFR 148.04-23 - Unslaked lime in bulk.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Unslaked lime in bulk. 148.04-23 Section 148.04-23... HAZARDOUS MATERIALS IN BULK Special Additional Requirements for Certain Material § 148.04-23 Unslaked lime in bulk. (a) Unslaked lime in bulk must be transported in unmanned, all steel, double-hulled barges...

  5. 33 CFR 127.313 - Bulk storage.

    Science.gov (United States)

    2010-07-01

    ...) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Operations § 127.313 Bulk storage. (a) The operator...: (1) LNG. (2) LPG. (3) Vessel fuel. (4) Oily waste from vessels. (5) Solvents, lubricants, paints, and...

  6. Polymer-fullerene bulk heterojunction solar cells

    NARCIS (Netherlands)

    Janssen, RAJ; Hummelen, JC; Saricifti, NS

    Nanostructured phase-separated blends, or bulk heterojunctions, of conjugated Polymers and fullerene derivatives form a very attractive approach to large-area, solid-state organic solar cells.The key feature of these cells is that they combine easy, processing from solution on a variety of

  7. Bulk amorphous Mg-based alloys

    DEFF Research Database (Denmark)

    Pryds, Nini

    2004-01-01

    are discussed in this paper. On the basis of these measurements phase diagrams of the different systems were constructed. Finally, it is demonstrated that when pressing the bulk amorphous alloy onto a metallic dies at temperatures within the supercooled liquid region, the alloy faithfully replicates the surface...

  8. Longitudinal bulk a coustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja

    2009-01-01

    Design, fabrication and characterization, in terms of mass sensitivity, is presented for a polycrystalline silicon longitudinal bulk acoustic cantilever. The device is operated in air at 51 MHz, resulting in a mass sensitivity of 100 HZ/fg (1 fg = 10{su−15 g). The initial characterization is cond...

  9. Bulk viscosity in 2SC quark matter

    International Nuclear Information System (INIS)

    Alford, Mark G; Schmitt, Andreas

    2007-01-01

    The bulk viscosity of three-flavour colour-superconducting quark matter originating from the nonleptonic process u + s ↔ u + d is computed. It is assumed that up and down quarks form Cooper pairs while the strange quark remains unpaired (2SC phase). A general derivation of the rate of strangeness production is presented, involving contributions from a multitude of different subprocesses, including subprocesses that involve different numbers of gapped quarks as well as creation and annihilation of particles in the condensate. The rate is then used to compute the bulk viscosity as a function of the temperature, for an external oscillation frequency typical of a compact star r-mode. We find that, for temperatures far below the critical temperature T c for 2SC pairing, the bulk viscosity of colour-superconducting quark matter is suppressed relative to that of unpaired quark matter, but for T ∼> T c /30 the colour-superconducting quark matter has a higher bulk viscosity. This is potentially relevant for the suppression of r-mode instabilities early in the life of a compact star

  10. Combating wear in bulk solids handling plants

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    A total of five papers presented at a seminar on problems of wear caused by abrasive effects of materials in bulk handling. Topics of papers cover the designer viewpoint, practical experience from the steel, coal, cement and quarry industries to create an awareness of possible solutions.

  11. THE OPTIMIZATION OF PLUSH YARNS BULKING PROCESS

    Directory of Open Access Journals (Sweden)

    VINEREANU Adam

    2014-05-01

    Full Text Available This paper presents the experiments that were conducted on the installation of continuous bulking and thermofixing “SUPERBA” type TVP-2S for optimization of the plush yarns bulking process. There were considered plush yarns Nm 6.5/2, made of the fibrous blend of 50% indigenous wool sort 41 and 50% PES. In the first stage, it performs a thermal treatment with a turboprevaporizer at a temperature lower than thermofixing temperature, at atmospheric pressure, such that the plush yarns - deposed in a freely state on a belt conveyor - are uniformly bulking and contracting. It was followed the mathematical modeling procedure, working with a factorial program, rotatable central composite type, and two independent variables. After analyzing the parameters that have a direct influence on the bulking degree, there were selected the pre-vaporization temperature (coded x1,oC and the velocity of belt inside pre-vaporizer (coded x 2, m/min. As for the dependent variable, it was chosen the plush yarn diameter (coded y, mm. There were found the coordinates of the optimal point, and then this pair of values was verified in practice. These coordinates are: x1optim= 90oC and x 2optim= 6.5 m/min. The conclusion is that the goal was accomplished: it was obtained a good cover degree f or double-plush carpets by reducing the number of tufts per unit surface.

  12. Characteristics of bulk liquid undercooling and crystallization ...

    Indian Academy of Sciences (India)

    Characteristics of bulk liquid undercooling and crystallization behaviors ... cooling rate is fixed, the change of undercooling depends on the melt processing tem- ... solidification and a deep knowledge of undercooling of ... evolution, to obtain the information for the nucleation and ..... When cooling rate is fixed, the change.

  13. A stereoscopic look into the bulk

    Energy Technology Data Exchange (ETDEWEB)

    Czech, Bartłomiej; Lamprou, Lampros; McCandlish, Samuel; Mosk, Benjamin [Stanford Institute for Theoretical Physics, Department of Physics, Stanford University,Stanford, CA 94305 (United States); Sully, James [Theory Group, SLAC National Accelerator LaboratoryMenlo Park, CA 94025 (United States)

    2016-07-26

    We present the foundation for a holographic dictionary with depth perception. The dictionary consists of natural CFT operators whose duals are simple, diffeomorphism-invariant bulk operators. The CFT operators of interest are the “OPE blocks,” contributions to the OPE from a single conformal family. In holographic theories, we show that the OPE blocks are dual at leading order in 1/N to integrals of effective bulk fields along geodesics or homogeneous minimal surfaces in anti-de Sitter space. One widely studied example of an OPE block is the modular Hamiltonian, which is dual to the fluctuation in the area of a minimal surface. Thus, our operators pave the way for generalizing the Ryu-Takayanagi relation to other bulk fields. Although the OPE blocks are non-local operators in the CFT, they admit a simple geometric description as fields in kinematic space — the space of pairs of CFT points. We develop the tools for constructing local bulk operators in terms of these non-local objects. The OPE blocks also allow for conceptually clean and technically simple derivations of many results known in the literature, including linearized Einstein’s equations and the relation between conformal blocks and geodesic Witten diagrams.

  14. Bulk viscous cosmology in early Universe

    Indian Academy of Sciences (India)

    The effect of bulk viscosity on the early evolution of Universe for a spatially homogeneous and isotropic Robertson-Walker model is considered. Einstein's field equations are solved by using `gamma-law' equation of state = ( - 1)ρ, where the adiabatic parameter gamma () depends on the scale factor of the model.

  15. Failure by fracture in bulk metal forming

    DEFF Research Database (Denmark)

    Silva, C.M.A.; Alves, Luis M.; Nielsen, Chris Valentin

    2015-01-01

    This paper revisits formability in bulk metal forming in the light of fundamental concepts of plasticity,ductile damage and crack opening modes. It proposes a new test to appraise the accuracy, reliability and validity of fracture loci associated with crack opening by tension and out-of-plane shear...

  16. Hexaferrite multiferroics: from bulk to thick films

    Science.gov (United States)

    Koutzarova, T.; Ghelev, Ch; Peneva, P.; Georgieva, B.; Kolev, S.; Vertruyen, B.; Closset, R.

    2018-03-01

    We report studies of the structural and microstructural properties of Sr3Co2Fe24O41 in bulk form and as thick films. The precursor powders for the bulk form were prepared following the sol-gel auto-combustion method. The prepared pellets were synthesized at 1200 °C to produce Sr3Co2Fe24O41. The XRD spectra of the bulks showed the characteristic peaks corresponding to the Z-type hexaferrite structure as a main phase and second phases of CoFe2O4 and Sr3Fe2O7-x. The microstructure analysis of the cross-section of the bulk pellets revealed a hexagonal sheet structure. Large areas were observed of packages of hexagonal sheets where the separate hexagonal particles were ordered along the c axis. Sr3Co2Fe24O41 thick films were deposited from a suspension containing the Sr3Co2Fe24O41 powder. The microstructural analysis of the thick films showed that the particles had the perfect hexagonal shape typical for hexaferrites.

  17. Integration of bulk piezoelectric materials into microsystems

    Science.gov (United States)

    Aktakka, Ethem Erkan

    Bulk piezoelectric ceramics, compared to deposited piezoelectric thin-films, provide greater electromechanical coupling and charge capacity, which are highly desirable in many MEMS applications. In this thesis, a technology platform is developed for wafer-level integration of bulk piezoelectric substrates on silicon, with a final film thickness of 5-100microm. The characterized processes include reliable low-temperature (200°C) AuIn diffusion bonding and parylene bonding of bulk-PZT on silicon, wafer-level lapping of bulk-PZT with high-uniformity (+/-0.5microm), and low-damage micro-machining of PZT films via dicing-saw patterning, laser ablation, and wet-etching. Preservation of ferroelectric and piezoelectric properties is confirmed with hysteresis and piezo-response measurements. The introduced technology offers higher material quality and unique advantages in fabrication flexibility over existing piezoelectric film deposition methods. In order to confirm the preserved bulk properties in the final film, diaphragm and cantilever beam actuators operating in the transverse-mode are designed, fabricated and tested. The diaphragm structure and electrode shapes/sizes are optimized for maximum deflection through finite-element simulations. During tests of fabricated devices, greater than 12microm PP displacement is obtained by actuation of a 1mm2 diaphragm at 111kHz with integration of a 50-80% efficient power management IC, which incorporates a supply-independent bias circuitry, an active diode for low-dropout rectification, a bias-flip system for higher efficiency, and a trickle battery charger. The overall system does not require a pre-charged battery, and has power consumption of <1microW in active-mode (measured) and <5pA in sleep-mode (simulated). Under lg vibration at 155Hz, a 70mF ultra-capacitor is charged from OV to 1.85V in 50 minutes.

  18. An acoustic prion assay

    Directory of Open Access Journals (Sweden)

    Gordon Hayward

    2016-12-01

    Full Text Available An acoustic prion assay has been demonstrated for sheep brain samples. Only five false positives and no false negatives were observed in a test of 45 positive and 45 negative samples. The acoustic prion sensor was constructed using a thickness shear mode quartz resonator coated with a covalently bound recombinant prion protein. The characteristic indicator of a scrapie infected sheep brain sample was an observed shoulder in the frequency decrease in response to a sample.The response of the sensor aligns with a conformational shift in the surface protein and with the propagation mechanism of the disease. This alignment is evident in the response timing and shape, dependence on concentration, cross species behaviour and impact of blood plasma. This alignment is far from sufficient to prove the mechanism of the sensor but it does offer the possibility of a rapid and inexpensive additional tool to explore prion disease. Keywords: Prions, Thickness shear mode quartz sensor

  19. Assay of oestrogen

    International Nuclear Information System (INIS)

    Edwards, J.C.

    1981-01-01

    A particular problem with the direct radioimmunoassay of unconjugated oestriol in pregnancy is caused by the increased amount of steroid-binding proteins present in pregnancy serum and plasma. The steroid-binding proteins react with oestriol and 125 I-labelled oestriol during the assay procedure and the steroid-protein bound 125 I-labelled oestriol is precipitated along with the antibody-bound 125 I-labelled oestriol by the ammonium sulphate solution separation system. A novel method is described whereby progesterone (1-20 μg/ml) is used to block the action of steroid-binding proteins in pregnancy serum and plasma samples, thus minimizing interference in a direct radioimmunoassay for unconjugated oestriol using a specific anti-oestriol serum. (U.K.)

  20. Amalgamation of interacting light beamlets in Kerr-type media

    DEFF Research Database (Denmark)

    Christiansen, Peter Leth; Rasmussen, Kim; Berge, L

    1997-01-01

    The interaction of optical filaments in bulk self-focusing media is investigated theoretically and numerically. The nature of this interaction is shown to vary with the incident individual powers and relative phases of the beamlets. By means of virial arguments supported by numerical results it i...

  1. Bulk solitary waves in elastic solids

    Science.gov (United States)

    Samsonov, A. M.; Dreiden, G. V.; Semenova, I. V.; Shvartz, A. G.

    2015-10-01

    A short and object oriented conspectus of bulk solitary wave theory, numerical simulations and real experiments in condensed matter is given. Upon a brief description of the soliton history and development we focus on bulk solitary waves of strain, also known as waves of density and, sometimes, as elastic and/or acoustic solitons. We consider the problem of nonlinear bulk wave generation and detection in basic structural elements, rods, plates and shells, that are exhaustively studied and widely used in physics and engineering. However, it is mostly valid for linear elasticity, whereas dynamic nonlinear theory of these elements is still far from being completed. In order to show how the nonlinear waves can be used in various applications, we studied the solitary elastic wave propagation along lengthy wave guides, and remarkably small attenuation of elastic solitons was proven in physical experiments. Both theory and generation for strain soliton in a shell, however, remained unsolved problems until recently, and we consider in more details the nonlinear bulk wave propagation in a shell. We studied an axially symmetric deformation of an infinite nonlinearly elastic cylindrical shell without torsion. The problem for bulk longitudinal waves is shown to be reducible to the one equation, if a relation between transversal displacement and the longitudinal strain is found. It is found that both the 1+1D and even the 1+2D problems for long travelling waves in nonlinear solids can be reduced to the Weierstrass equation for elliptic functions, which provide the solitary wave solutions as appropriate limits. We show that the accuracy in the boundary conditions on free lateral surfaces is of crucial importance for solution, derive the only equation for longitudinal nonlinear strain wave and show, that the equation has, amongst others, a bidirectional solitary wave solution, which lead us to successful physical experiments. We observed first the compression solitary wave in the

  2. Media Literacy Bibliography.

    Science.gov (United States)

    Duncan, Barry

    1989-01-01

    Provides an up-to-date bibliography of resources available for teaching media literacy. Groups resources into the areas of media education methodology, mass media texts, general background, television, film, the news and medium of print, advertising, gender and the media, popular culture, popular music and rock video, periodicals, and…

  3. Mixture models for single-cell assays with applications to vaccine studies

    OpenAIRE

    Finak, Greg; McDavid, Andrew; Chattopadhyay, Pratip; Dominguez, Maria; De Rosa, Steve; Roederer, Mario; Gottardo, Raphael

    2013-01-01

    Blood and tissue are composed of many functionally distinct cell subsets. In immunological studies, these can be measured accurately only using single-cell assays. The characterization of these small cell subsets is crucial to decipher system-level biological changes. For this reason, an increasing number of studies rely on assays that provide single-cell measurements of multiple genes and proteins from bulk cell samples. A common problem in the analysis of such data is to identify biomarkers...

  4. Transuranic waste assay instrumentation: new developments and directions at the Los Alamos Scientific Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Close, D.A.; Umbarger, C.J.; West, L.; Smith, W.J.; Cates, M.R.; Noel, B.W.; Honey, F.J.; Franks, L.A.; Pigg, J.L.; Trundle, A.S.

    1978-01-01

    The Los Alamos Scientific Laboratory is developing assay instrumentation for the quantitative analysis of transuranic materials found in bulk solid wastes generated by Department of Energy facilities and by the commercial nuclear power industry. This also includes wastes generated in the decontamination and decommissioning of facilities and wastes generated during burial ground exhumation. The assay instrumentation will have a detection capability for the transuranics of less than 10 nCi of activity per gram of waste whenever practicable.

  5. Transuranic waste assay instrumentation: new developments and directions at the Los Alamos Scientific Laboratory

    International Nuclear Information System (INIS)

    Close, D.A.; Umbarger, C.J.; West, L.; Smith, W.J.; Cates, M.R.; Noel, B.W.; Honey, F.J.; Franks, L.A.; Pigg, J.L.; Trundle, A.S.

    1978-01-01

    The Los Alamos Scientific Laboratory is developing assay instrumentation for the quantitative analysis of transuranic materials found in bulk solid wastes generated by Department of Energy facilities and by the commercial nuclear power industry. This also includes wastes generated in the decontamination and decommissioning of facilities and wastes generated during burial ground exhumation. The assay instrumentation will have a detection capability for the transuranics of less than 10 nCi of activity per gram of waste whenever practicable

  6. Understanding Social Media Logic

    OpenAIRE

    José van Dijck; Thomas Poell

    2013-01-01

    Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions and rules of social interaction. In this article, we examine the intricate dynamic between social media platforms, mass media, users, and social institutions by calling attention to social media log...

  7. Social media influencer marketing

    OpenAIRE

    Isosuo, Heli

    2016-01-01

    The marketing field is changing simultaneously with the digital world. Social media is getting more and more important to marketers, and there is a need to stand out in the social media noise. Social media influencer marketing could be a good alternative to other types of marketing. A need from the consignor and the interest of the author were the motivations for conducting the study. Sääskilahti Consulting has a social media influencer network Somevaikuttajat, which is offering social media ...

  8. Fluctuation effects in bulk polymer phase behavior

    International Nuclear Information System (INIS)

    Bates, F.S.; Rosedale, J.H.; Stepanek, P.; Lodge, T.P.; Wiltzius, P.; Hjelm R, Jr.; Fredrickson, G.H.

    1990-01-01

    Bulk polymer-polymer, and block copolymer, phase behaviors have traditionally been interpreted using mean-field theories. Recent small-angle neutron scattering (SANS) studies of critical phenomena in model binary polymer mixtures confirm that non-mean-field behavior is restricted to a narrow range of temperatures near the critical point, in close agreement with the Ginzburg criterion. In contrast, strong derivations from mean-field behavior are evident in SANS and rheological measurements on model block copolymers more than 50C above the order-disorder transition (ODT), which can be attributed to sizeable composition fluctuations. Such fluctuation effects undermine the mean-field assumption, conventionally applied to bulk polymers, and result in qualitative changes in phase behavior, such as the elimination of a thermodynamic stability limit in these materials. The influence of fluctuation effects on block copolymer and binary mixture phase behavior is compared and contrasted in this presentation

  9. Nuclear Matter Bulk Parameter Scales and Correlations

    International Nuclear Information System (INIS)

    Santos, B. M.; Delfino, A.; Dutra, M.; Lourenço, O.

    2015-01-01

    We study the arising of correlations among some isovector bulk parameters in nonrelativistic and relativistic hadronic mean-field models. For the former, we investigate correlations in the nonrelativistic (NR) limit of relativistic point-coupling models. We provide analytical correlations, for the NR limit model, between the symmetry energy and its derivatives, namely, the symmetry energy slope, curvature, skewness and fourth order derivative, discussing the conditions in which they are linear ones. We also show that some correlations presented in the NR limit model are reproduced for relativistic models presenting cubic and quartic self-interactions in its scalar field. As a direct application of such linear correlations, we remark its association with possible crossing points in the density dependence of the linearly correlated bulk parameter. (author)

  10. Structural determinants in the bulk heterojunction.

    Science.gov (United States)

    Acocella, Angela; Höfinger, Siegfried; Haunschmid, Ernst; Pop, Sergiu C; Narumi, Tetsu; Yasuoka, Kenji; Yasui, Masato; Zerbetto, Francesco

    2018-02-21

    Photovoltaics is one of the key areas in renewable energy research with remarkable progress made every year. Here we consider the case of a photoactive material and study its structural composition and the resulting consequences for the fundamental processes driving solar energy conversion. A multiscale approach is used to characterize essential molecular properties of the light-absorbing layer. A selection of bulk-representative pairs of donor/acceptor molecules is extracted from the molecular dynamics simulation of the bulk heterojunction and analyzed at increasing levels of detail. Significantly increased ground state energies together with an array of additional structural characteristics are identified that all point towards an auxiliary role of the material's structural organization in mediating charge-transfer and -separation. Mechanistic studies of the type presented here can provide important insights into fundamental principles governing solar energy conversion in next-generation photovoltaic devices.

  11. ANFO bulk loading in coal mines

    Energy Technology Data Exchange (ETDEWEB)

    Gajjar, A.

    1987-08-01

    With India's total coal production projected to increase from 152 to 237 million tons by 1990, net additional production from new mines must be more because of substantial depletion in existing mines. This article discusses the best possible application of explosive techniques in open-cast coal mines to economize production cost. The most energy-efficient and safest explosive is ANFO (ammonium nitrate, fuel oil); however, manual charging by INFO is not possible. Therefore, the solution is the application of bulk-loading systems of ANFO for giant mining operations. Cost of blasting per ton of coal production in India is in the range of Rs 25. Thus, the author suggests it will be the responsibility of mining engineers to see that the ANFO based bulk-loading system is implemented and the cost of production per ton reduced to Rs 19.50.

  12. Nonlinear AC susceptibility, surface and bulk shielding

    Science.gov (United States)

    van der Beek, C. J.; Indenbom, M. V.; D'Anna, G.; Benoit, W.

    1996-02-01

    We calculate the nonlinear AC response of a thin superconducting strip in perpendicular field, shielded by an edge current due to the geometrical barrier. A comparison with the results for infinite samples in parallel field, screened by a surface barrier, and with those for screening by a bulk current in the critical state, shows that the AC response due to a barrier has general features that are independent of geometry, and that are significantly different from those for screening by a bulk current in the critical state. By consequence, the nonlinear (global) AC susceptibility can be used to determine the origin of magnetic irreversibility. A comparison with experiments on a Bi 2Sr 2CaCu 2O 8+δ crystal shows that in this material, the low-frequency AC screening at high temperature is mainly due to the screening by an edge current, and that this is the unique source of the nonlinear magnetic response at temperatures above 40 K.

  13. Multilayer Integrated Film Bulk Acoustic Resonators

    CERN Document Server

    Zhang, Yafei

    2013-01-01

    Multilayer Integrated Film Bulk Acoustic Resonators mainly introduces the theory, design, fabrication technology and application of a recently developed new type of device, multilayer integrated film bulk acoustic resonators, at the micro and nano scale involving microelectronic devices, integrated circuits, optical devices, sensors and actuators, acoustic resonators, micro-nano manufacturing, multilayer integration, device theory and design principles, etc. These devices can work at very high frequencies by using the newly developed theory, design, and fabrication technology of nano and micro devices. Readers in fields of IC, electronic devices, sensors, materials, and films etc. will benefit from this book by learning the detailed fundamentals and potential applications of these advanced devices. Prof. Yafei Zhang is the director of the Ministry of Education’s Key Laboratory for Thin Films and Microfabrication Technology, PRC; Dr. Da Chen was a PhD student in Prof. Yafei Zhang’s research group.

  14. Internal shear cracking in bulk metal forming

    DEFF Research Database (Denmark)

    Christiansen, Peter; Nielsen, Chris Valentin; Bay, Niels Oluf

    2017-01-01

    This paper presents an uncoupled ductile damage criterion for modelling the opening and propagation of internal shear cracks in bulk metal forming. The criterion is built upon the original work on the motion of a hole subjected to shear with superimposed tensile stress triaxiality and its overall...... performance is evaluated by means of side-pressing formability tests in Aluminium AA2007-T6 subjected to different levels of pre-strain. Results show that the new proposed criterionis able to combine simplicity with efficiency for predicting the onset of fracture and the crack propagation path for the entire...... cracking to internal cracks formed undert hree-dimensional states of stress that are typical of bulk metal forming....

  15. Induction detection of concealed bulk banknotes

    International Nuclear Information System (INIS)

    Fuller, Christopher; Chen, Antao

    2011-01-01

    Bulk cash smuggling is a serious issue that has grown in volume in recent years. By building on the magnetic characteristics of paper currency, induction sensing is found to be capable of quickly detecting large masses of banknotes. The results show that this method is effective in detecting bulk cash through concealing materials such as plastics, cardboards, fabrics and aluminum foil. The significant difference in the observed phase between the received signals caused by conducting materials and ferrite compounds, found in banknotes, provides a good indication that this process can overcome the interference by metal objects in a real sensing application. This identification strategy has the potential to not only detect the presence of banknotes, but also the number, while still eliminating false positives caused by metal objects

  16. Induction detection of concealed bulk banknotes

    Science.gov (United States)

    Fuller, Christopher; Chen, Antao

    2012-06-01

    The smuggling of bulk cash across borders is a serious issue that has increased in recent years. In an effort to curb the illegal transport of large numbers of paper bills, a detection scheme has been developed, based on the magnetic characteristics of bank notes. The results show that volumes of paper currency can be detected through common concealing materials such as plastics, cardboard, and fabrics making it a possible potential addition to border security methods. The detection scheme holds the potential of also reducing or eliminating false positives caused by metallic materials found in the vicinity, by observing the stark difference in received signals caused by metal and currency. The detection scheme holds the potential to detect for both the presence and number of concealed bulk notes, while maintaining the ability to reduce false positives caused by metal objects.

  17. Bulk viscous cosmology with causal transport theory

    International Nuclear Information System (INIS)

    Piattella, Oliver F.; Fabris, Júlio C.; Zimdahl, Winfried

    2011-01-01

    We consider cosmological scenarios originating from a single imperfect fluid with bulk viscosity and apply Eckart's and both the full and the truncated Müller-Israel-Stewart's theories as descriptions of the non-equilibrium processes. Our principal objective is to investigate if the dynamical properties of Dark Matter and Dark Energy can be described by a single viscous fluid and how such description changes when a causal theory (Müller-Israel-Stewart's, both in its full and truncated forms) is taken into account instead of Eckart's non-causal one. To this purpose, we find numerical solutions for the gravitational potential and compare its behaviour with the corresponding ΛCDM case. Eckart's and the full causal theory seem to be disfavoured, whereas the truncated theory leads to results similar to those of the ΛCDM model for a bulk viscous speed in the interval 10 −11 || cb 2 ∼ −8

  18. Raman characterization of bulk ferromagnetic nanostructured graphite

    International Nuclear Information System (INIS)

    Pardo, Helena; Divine Khan, Ngwashi; Faccio, Ricardo; Araújo-Moreira, F.M.; Fernández-Werner, Luciana

    2012-01-01

    Raman spectroscopy was used to characterize bulk ferromagnetic graphite samples prepared by controlled oxidation of commercial pristine graphite powder. The G:D band intensity ratio, the shape and position of the 2D band and the presence of a band around 2950 cm -1 showed a high degree of disorder in the modified graphite sample, with a significant presence of exposed edges of graphitic planes as well as a high degree of attached hydrogen atoms.

  19. Depositing bulk or micro-scale electrodes

    Science.gov (United States)

    Shah, Kedar G.; Pannu, Satinderpall S.; Tolosa, Vanessa; Tooker, Angela C.; Sheth, Heeral J.; Felix, Sarah H.; Delima, Terri L.

    2016-11-01

    Thicker electrodes are provided on microelectronic device using thermo-compression bonding. A thin-film electrical conducting layer forms electrical conduits and bulk depositing provides an electrode layer on the thin-film electrical conducting layer. An insulating polymer layer encapsulates the electrically thin-film electrical conducting layer and the electrode layer. Some of the insulating layer is removed to expose the electrode layer.

  20. Theory of thermal expansivity and bulk modulus

    International Nuclear Information System (INIS)

    Kumar, Munish

    2005-01-01

    The expression for thermal expansivity and bulk modulus, claimed by Shanker et al. to be new [Physica B 233 (1977) 78; 245 (1998) 190; J. Phys. Chem. Solids 59 (1998) 197] are compared with the theory of high pressure-high temperature reported by Kumar and coworkers. It is concluded that the Shanker formulation and the relations based on this are equal to the approach of Kumar et al. up to second order

  1. Depleted Bulk Heterojunction Colloidal Quantum Dot Photovoltaics

    KAUST Repository

    Barkhouse, D. Aaron R.

    2011-05-26

    The first solution-processed depleted bulk heterojunction colloidal quantum dot solar cells are presented. The architecture allows for high absorption with full depletion, thereby breaking the photon absorption/carrier extraction compromise inherent in planar devices. A record power conversion of 5.5% under simulated AM 1.5 illumination conditions is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. A bulk viscosity driven inflationary model

    International Nuclear Information System (INIS)

    Waga, I.; Falcao, R.C.; Chanda, R.

    1985-01-01

    Bulk viscosity associated with the production of heavy particles during the GUT phase transition can lead to exponential or 'generalized' inflation. The condition of inflation proposed is independent of the details of the phase transition and remains unaltered in presence of a cosmological constant. Such mechanism avoids the extreme supercooling and reheating needed in the usual inflationary models. The standard baryongenesis mechanism can be maintained. (Author) [pt

  3. Evidence for Bulk Ripplocations in Layered Solids

    Science.gov (United States)

    Gruber, Jacob; Lang, Andrew C.; Griggs, Justin; Taheri, Mitra L.; Tucker, Garritt J.; Barsoum, Michel W.

    2016-09-01

    Plastically anisotropic/layered solids are ubiquitous in nature and understanding how they deform is crucial in geology, nuclear engineering, microelectronics, among other fields. Recently, a new defect termed a ripplocation-best described as an atomic scale ripple-was proposed to explain deformation in two-dimensional solids. Herein, we leverage atomistic simulations of graphite to extend the ripplocation idea to bulk layered solids, and confirm that it is essentially a buckling phenomenon. In contrast to dislocations, bulk ripplocations have no Burgers vector and no polarity. In graphite, ripplocations are attracted to other ripplocations, both within the same, and on adjacent layers, the latter resulting in kink boundaries. Furthermore, we present transmission electron microscopy evidence consistent with the existence of bulk ripplocations in Ti3SiC2. Ripplocations are a topological imperative, as they allow atomic layers to glide relative to each other without breaking the in-plane bonds. A more complete understanding of their mechanics and behavior is critically important, and could profoundly influence our current understanding of how graphite, layered silicates, the MAX phases, and many other plastically anisotropic/layered solids, deform and accommodate strain.

  4. Accelerating universes driven by bulk particles

    International Nuclear Information System (INIS)

    Brito, F.A.; Cruz, F.F.; Oliveira, J.F.N.

    2005-01-01

    We consider our universe as a 3d domain wall embedded in a 5d dimensional Minkowski space-time. We address the problem of inflation and late time acceleration driven by bulk particles colliding with the 3d domain wall. The expansion of our universe is mainly related to these bulk particles. Since our universe tends to be permeated by a large number of isolated structures, as temperature diminishes with the expansion, we model our universe with a 3d domain wall with increasing internal structures. These structures could be unstable 2d domain walls evolving to fermi-balls which are candidates to cold dark matter. The momentum transfer of bulk particles colliding with the 3d domain wall is related to the reflection coefficient. We show a nontrivial dependence of the reflection coefficient with the number of internal dark matter structures inside the 3d domain wall. As the population of such structures increases the velocity of the domain wall expansion also increases. The expansion is exponential at early times and polynomial at late times. We connect this picture with string/M-theory by considering BPS 3d domain walls with structures which can appear through the bosonic sector of a five-dimensional supergravity theory

  5. The comet assay in testing the potential genotoxicity of nanomaterials

    Directory of Open Access Journals (Sweden)

    Amaya Azqueta

    2015-06-01

    Full Text Available In the last two decades the production and use of nanomaterials (NMs has impressively increased. Their small size, given a mass equal to that of the corresponding bulk material, implies an increase in the surface area and consequently in the number of atoms that can be reactive. They possess different physical, chemical and biological properties compared to bulk materials of the same composition, which makes them very interesting and valuable for many different applications in technology, energy, construction, electronics, agriculture, optics, paints, textiles, food, cosmetics, medicine... Toxicological assessment of NMs is crucial; the same properties that make them interesting also make them potentially harmful for health and the environment. However, the term NM covers many different kinds of particle , and so there is no simple, standard approach to assessing their toxicity. NMs can enter the cell, interact with cell components and even penetrate the nucleus and interfere with the genetic material. Among the different branches of toxicology, genotoxicity is a main area of concern since it is closely related with the carcinogenic potential of compounds. The Organisation for Economic Co-operation and Development (OECD has published internationally agreed in vitro and in vivo validated test methods to evaluate different genotoxic endpoints of chemicals, including chromosome and gene mutations, and DNA breaks. However not all the assays are suitable to study the genotoxic potential of NMs as has been shown by the OECD Working Party on Manufactured Nanomaterials (WPMN. Moreover, alterations to DNA bases, which are precursors to mutations and of great importance in elucidating the mechanism of action of NMs, are not covered by the OECD guidelines. The in vivo standard comet assay (which measures DNA breaks and alkali-labile sites was included in the OECD assays battery in September 2014 while the in vitro standard comet assay is currently under

  6. IVF culture media: past, present and future.

    Science.gov (United States)

    Chronopoulou, Elpiniki; Harper, Joyce C

    2015-01-01

    The advances in the world of IVF during the last decades have been rapid and impressive and culture media play a major role in this success. Until the 1980s fertility centers made their media in house. Nowadays, there are numerous commercially available culture media that contain various components including nutrients, vitamins and growth factors. This review goes through the past, present and future of IVF culture media and explores their composition and quality assessment. A computerized search was performed in PubMed regarding IVF culture media including results from 1929 until March 2014. Information was gathered from the websites of companies who market culture media, advertising material, instructions for use and certificates of analysis. The regulation regarding IVF media mainly in the European Union (EU) but also in non-European countries was explored. The keyword 'IVF culture media' gave 923 results in PubMed and 'embryo culture media' 12 068 results dating from 1912 until March 2014, depicting the increased scientific activity in this field. The commercialization of IVF culture media has increased the standards bringing a great variety of options into clinical practice. However, it has led to reduced transparency and comparisons of brand names that do not facilitate the scientific dialogue. Furthermore, there is some evidence suggesting that suboptimal culture conditions could cause long-term reprogramming in the embryo as the periconception period is particularly susceptible to epigenetic alterations. IVF media are now classified as class III medical devices and only CE (Conformité Européene)-marked media should be used in the EU. The CE marking of IVF culture media is a significant development in the field. However, the quality and efficiency of culture media should be monitored closely. Well-designed randomized controlled trials, large epidemiological studies and full transparency should be the next steps. Reliable, standardized models assessing

  7. Sodium Flux Growth of Bulk Gallium Nitride

    Science.gov (United States)

    Von Dollen, Paul Martin

    This dissertation focused on development of a novel apparatus and techniques for crystal growth of bulk gallium nitride (GaN) using the sodium flux method. Though several methods exist to produce bulk GaN, none have been commercialized on an industrial scale. The sodium flux method offers potentially lower cost production due to relatively mild process conditions while maintaining high crystal quality. But the current equipment and methods for sodium flux growth of bulk GaN are generally not amenable to large-scale crystal growth or in situ investigation of growth processes, which has hampered progress. A key task was to prevent sodium loss or migration from the sodium-gallium growth melt while permitting N2 gas to access the growing crystal, which was accomplished by implementing a reflux condensing stem along with a reusable sealed capsule. The reflux condensing stem also enabled direct monitoring and control of the melt temperature, which has not been previously reported for the sodium flux method. Molybdenum-based materials were identified from a corrosion study as candidates for direct containment of the corrosive sodium-gallium melt. Successful introduction of these materials allowed implementation of a crucible-free containment system, which improved process control and can potentially reduce crystal impurity levels. Using the new growth system, the (0001) Ga face (+c plane) growth rate was >50 mum/hr, which is the highest bulk GaN growth rate reported for the sodium flux method. Omega X-ray rocking curve (?-XRC) measurements indicated the presence of multiple grains, though full width at half maximum (FWHM) values for individual peaks were 1020 atoms/cm3, possibly due to reactor cleaning and handling procedures. This dissertation also introduced an in situ technique to correlate changes in N2 pressure with dissolution of nitrogen and precipitation of GaN from the sodium-gallium melt. Different stages of N2 pressure decay were identified and linked to

  8. Comparison of the Vidas C. difficile GDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluD for Detection of Clostridium difficile in Fecal Samples.

    Science.gov (United States)

    Davies, K A; Berry, C E; Morris, K A; Smith, R; Young, S; Davis, T E; Fuller, D D; Buckner, R J; Wilcox, M H

    2015-06-01

    Prevention and management of Clostridium difficile infection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficile glutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  9. Cytotoxic and biological effects of bulk fill composites on rat cortical neuron cells.

    Science.gov (United States)

    Kamalak, Hakan; Kamalak, Aliye; Taghizadehghalehjoughi, Ali; Hacımüftüoğlu, Ahmet; Nalcı, Kemal Alp

    2018-03-28

    The aim of this study was to investigate potential cellular responses and biological effects of new generation dental composites on cortical neuron cells in two different exposure times. The study group included five different bulk-fill flow able composites; Surefil SDR Flow, X-tra Base Flow, Venus Bulk Flow, Filtek Bulk Flow and Tetric-Evo Flow. They were filled in Teflon molds (Height: 4 mm, Width: 6 mm) and irradiated for 20 s. Cortical neuron cells were inoculated into 24-well plates. After 80% of the wells were coated, the 3 µm membrane was inserted and dental filling materials were added. The experiment was continued for 24 and 72 h. Cell viability measured by MTT assay test, total antioxidant and total oxidant status were examined using real assay diagnostic kits. The patterns of cell death (apoptosis) were analyzed using annexin V-FITC staining with flow cytometry. Β-defensins were quantitatively assessed by RT-PCR. IL-6, IL-8 and IL-10 cytokines were measured from the supernatants. All composites significantly affected analyses parameters during the exposure durations. Our data provide evidence that all dental materials tested are cytotoxic in acute phase and these effects are induced cellular death after different exposure periods. Significant cytotoxicity was detected in TE, XB, SS, FBF and VBF groups at 24 and 72 h, respectively.

  10. Bulk Building Material Characterization and Decontamination Using a Concrete Floor and Wall Contamination Profiling Technology

    International Nuclear Information System (INIS)

    Aggarwal, S.; Charters, G.; Blauvelt, D.

    2002-01-01

    The concrete profiling technology, RadPro(trademark) has four major components: a drill with a specialized cutting and sampling head, drill bits, a sample collection unit and a vacuum pump. The equipment in conjunction with portable radiometric instrumentation produces a profile of radiological or chemical contamination through the material being studied. The drill head is used under hammer action to penetrate hard surfaces. This causes the bulk material to be pulverized as the drill travels through the radioactive media efficiently transmitting to the sampling unit a representative sample of powdered bulk material. The profiling equipment is designed to sequentially collect all material from the hole. The bulk material samples are continuously retrieved by use of a specially designed vacuumed sample retrieval unit that prevents cross contamination of the clean retrieved samples. No circulation medium is required with this profiling process; therefore, the only by-product from drilling is the sample. The data quality, quantity, and representativeness may be used to produce an activity profile from the hot spot surface into the bulk building material. The activity data obtained during the profiling process is reduced and transferred to building drawings as part of a detailed report of the radiological problem. This activity profile may then be expanded to ultimately characterize the facility and expedite waste segregation and facility closure at a reduced cost and risk

  11. Influence of Bulk PDMS Network Properties on Water Wettability

    Science.gov (United States)

    Melillo, Matthew; Walker, Edwin; Klein, Zoe; Efimenko, Kirill; Genzer, Jan

    Poly(dimethylsiloxane) (PDMS) is one of the most common elastomers, with applications ranging from sealants and marine antifouling coatings to absorbents for water treatment. Fundamental understanding of how liquids spread on the surface of and absorb into PDMS networks is of critical importance for the design and use of another application - medical devices. We have systematically studied the effects of polymer molecular weight, loading of tetra-functional crosslinker, and end-group chemical functionality on the mechanical and surface properties of end-linked PDMS networks. Wettability was investigated through the sessile drop technique, wherein a DI water droplet was placed on the bulk network surface and droplet volume, shape, surface area, and contact angle were monitored as a function of time. Various silicone substrates ranging from incredibly soft and flexible materials (E' 50 kPa) to highly rigid networks (E' 5 MPa) were tested. The dynamic behavior of the droplet on the surfaces demonstrated equilibration times between the droplet and surface on the order of 5 minutes. Similar trends were observed for the commercial PDMS material, Sylgard-184. Our results have provided new evidence for the strong influence that substrate modulus and molecular network structure have on the wettability of PDMS elastomers. These findings will aid in the design and implementation of efficient, accurate, and safe PDMS-based medical devices and microfluidic materials that involve aqueous media.

  12. Unpacking New Media Literacy

    Directory of Open Access Journals (Sweden)

    Der-Thanq “victor” Chen

    2011-04-01

    Full Text Available The 21st century has marked an unprecedented advancement of new media. New media has become so pervasive that it has penetrated into every aspect of our society. New media literacy plays an essential role for any citizen to participate fully in the 21st century society. Researchers have documented that literacy has evolved historically from classic literacy (reading-writing-understanding to audiovisual literacy to digital literacy or information literacy and recently to new media literacy. A review of literature on media literacy reveals that there is a lack of thorough analysis of unique characteristics of new media and its impacts upon the notion of new media literacy. The purpose of the study is to unpack new media literacy and propose a framework for a systematic investigation of new media literacy.

  13. Parenting and Digital Media.

    Science.gov (United States)

    Coyne, Sarah M; Radesky, Jenny; Collier, Kevin M; Gentile, Douglas A; Linder, Jennifer Ruh; Nathanson, Amy I; Rasmussen, Eric E; Reich, Stephanie M; Rogers, Jean

    2017-11-01

    Understanding the family dynamic surrounding media use is crucial to our understanding of media effects, policy development, and the targeting of individuals and families for interventions to benefit child health and development. The Families, Parenting, and Media Workgroup reviewed the relevant research from the past few decades. We find that child characteristics, the parent-child relationship, parental mediation practices, and parents' own use of media all can influence children's media use, their attitudes regarding media, and the effects of media on children. However, gaps remain. First, more research is needed on best practices of parental mediation for both traditional and new media. Ideally, this research will involve large-scale, longitudinal studies that manage children from infancy to adulthood. Second, we need to better understand the relationship between parent media use and child media use and specifically how media may interfere with or strengthen parent-child relationships. Finally, longitudinal research on how developmental processes and individual child characteristics influence the intersection between media and family life is needed. The majority of children's media use takes place within a wider family dynamic. An understanding of this dynamic is crucial to understanding child media use as a whole. Copyright © 2017 by the American Academy of Pediatrics.

  14. Detection of Coxiella burnetii by PCR in bulk tank milk samples from dairy caprine herds in southeast of Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Khalili

    2015-02-01

    Full Text Available Objective: To use PCR for the detection of Coxiella burnetii (C. burnetii in bulk tank milk samples collected from dairy caprine herds in southeast Iran. Methods: In the present study, 31 goat bulk milk from 31 dairy goat herds were tested for C. burnetii using trans-PCR assay. The animals which their milk samples collected for this study were clinically healthy. Results: In total, 5 of 31 (16.12% goat milk samples were positive. Conclusions: The results of this study indicate clinically healthy dairy goats are important sources of C. burnetii infection in this area.

  15. Mass Media: The Invisible Environment.

    Science.gov (United States)

    Glessing, Robert J.; White, William P.

    This anthology for students of media consists of essays and articles grouped under four topics: media forms, media content, media environments, and "the last word." Media forms deals with the nature of these kinds of media: electronic, print, film, music, and comics, graffiti, and clothing. Media content contains articles on the news, advertising,…

  16. Media Pluralism and Diversity

    DEFF Research Database (Denmark)

    In the western world, a diverse and pluralistic media landscape is deemed essential for democracy. But how universal is media pluralism as a concept underpinning media policies? To what extent do normative approaches, regulatory dimensions and monitoring systems differ throughout the world......? Adopting a truly global, theoretical and multidisciplinary perspective, Media Pluralism and Diversity advances our understanding of media pluralism across the globe. It compares metrics developed in different parts of the world to assess levels of, or threats to, media pluralism. It identifies common...

  17. Social Media Reputation

    DEFF Research Database (Denmark)

    Etter, Michael Andreas; Ravasi, Davide; Colleoni, Elanor

    motivational drivers and contextual conditions associated with the formation of narratives in traditional news media and social media influence their content, diffusion, and impact significantly. Our analysis suggests that current theories of media reputation may provide an incomplete representation......Social media enable millions of users to create and disseminate narratives about organizations that increase their public exposure and shape public perceptions. In this paper, we draw on the sociology of news production and research on computer-mediated communication to discuss how different...... of the phenomenon, and highlight theoretically relevant differences and interrelationships between reputational dynamics involving news media and social media....

  18. Transfer points of belt conveyors operating with unfavorable bulk

    Energy Technology Data Exchange (ETDEWEB)

    Goehring, H [Technische Universitaet, Dresden (German Democratic Republic)

    1989-06-01

    Describes design of belt conveyor chutes that transfer bulk of surface mines from one conveyor to another. Conveyor belt velocity is a significant parameter. Unfavorable chute design may lead to bulk flow congestion, bulk velocity losses etc. The bulk flow process is analyzed, bulk flow velocities, belt inclinations and bulk feeding from 2 conveyors into one chute are taken into account. Conventional chutes have parabolic belt impact walls. An improved version with divided impact walls is proposed that maintains a relatively high bulk velocity, reduces friction at chute walls and decreases wear and dirt build-up. Design of the improved chute is explained. It is built to adapt to existing structures without major modifications. The angle between 2 belt conveyors can be up to 90 degrees, the best bulk transfer is noted at conveyor angles below 60 degrees. Various graphs and schemes are provided. 6 refs.

  19. Determination of Nitrate Reductase Assay Depending on the Microbial Growth

    International Nuclear Information System (INIS)

    El-Kabbany, H.M.

    2012-01-01

    A rapid micro-dilution assay for determination of the antimicrobial susceptibility of different bacterial isolates was developed. This assay is based on the ability of the most of viable organisms to reduce nitrates. The MIC or MBC could be determined by nitrate reductase (NR) only after 30 to 90 min of incubation depending on the behaviour of microbial growth. Bacterial viability is detected by a positive nitrite reduction rather than visible turbidity. The nitrate reduction assay was compared with standard micro-assay using 250 isolates of different taxa against 10 antibiotics belonging to different classes. An excellent agreement of 82.5 % was found between the two methods and only 17.5 % of 1794 trials showed difference in the determined MIC by tow-dilution interval above or below the MIC determined by the turbidimetric method under the same test conditions. However, the nitrate reduction assay was more rapid and sensitive in detecting viable bacteria and so, established an accurate estimate of the minimal inhibitory concentration (MIC) or the minimal bacterial concentration (MBC). The nitrate reduction assay offers the additional advantage that it could be used to determine the MBC without having to subculture the broth. 232 cases of resistance were detected by NR and 4 different media were tested for susceptibility test. The bacterial isolates were exposed to ultra violet (UV) light for different period

  20. AMAMM - All Media Are Mixed Media

    DEFF Research Database (Denmark)

    All Media Are Mixed Media Alle medier er blandingsmedier. Alle kunstarter er kompositte. Alle sanser er sammensatte. Alle medialiteter er miksede og mangfoldige. Alle er AMAMM. Denne påstand står centralt i ord-, billed- og medie-teoretikeren W.J.T. Mitchells forfatterskab. I hosstående bog tager...

  1. A Compton Suppressed Gamma Ray Counter For Radio Assay of Materials

    Science.gov (United States)

    Godfrey, Benjamin

    2016-03-01

    Rare event searches, such as direct dark matter experiments, require materials with ultra-low levels of natural radioactivity. We present a neutron activation analysis (NAA) technique for assaying metals, specifically titanium used for cryostat construction. Earlier attempts at NAA encountered limitations due to bulk activation via (n, p) reactions, which contributed to large continuum backgrounds due to Compton tails. Our method involves a heavy water shielded exposure to minimize (n,p) reactions and a sodium iodide shielded high purity germanium counter for the gamma ray assay. Preliminary results on assays for U/Th/K contamination in titaniumwill be presented.

  2. Brane Lorentz symmetry from Lorentz breaking in the bulk

    Energy Technology Data Exchange (ETDEWEB)

    Bertolami, O [Departamento de Fisica, Instituto Superior Tecnico, Avenida Rovisco Pais 1, 1049-001 Lisbon (Portugal); Carvalho, C [Departamento de Fisica, Instituto Superior Tecnico, Avenida Rovisco Pais 1, 1049-001 Lisbon (Portugal)

    2007-05-15

    We propose the mechanism of spontaneous symmetry breaking of a bulk vector field as a way to generate the selection of bulk dimensions invisible to the standard model confined to the brane. By assigning a nonvanishing vacuum value to the vector field, a direction is singled out in the bulk vacuum, thus breaking the bulk Lorentz symmetry. We present the condition for induced Lorentz symmetry on the brane, as phenomenologically required.

  3. Posterior bulk-filled resin composite restorations.

    DEFF Research Database (Denmark)

    van Dijken, Jan WV; Pallesen, Ulla

    2016-01-01

    up to 4mm as needed to fill the cavity 2mm short of the occlusal cavosurface. The occlusal part was completed with the nano-hybrid resin composite (Ceram X mono+). In the other cavity, the resin composite-only (Ceram X mono+) was placed in 2mm increments. The restorations were evaluated using...... Class II, 4 SDR-CeramX mono+ and 6 CeramXmono+-only restorations. The main reasons for failurewere tooth fracture (6) and secondary caries (4). The annual failure rate (AFR) for all restorations (Class I and II) was for the bulk-filled-1.1% and for the resin composite-only restorations 1...

  4. Characterization and bulk properties of oxides

    International Nuclear Information System (INIS)

    Sonder, E.; Connolly, T.F.

    1979-06-01

    The bulk properties of oxides are divided into two classes, intrinsic properties which depend solely on the identity of the material, and extrinsic ones, which differ for different samples of the same compound. Sources of tabulated numerical values of intrinsic properties are given and modern developments in information storage and retrieval are discussed. Extrinsic properties are shown to depend on defects and trace impurities in the samples. Techniques of trace impurity analysis are discussed and realistic limits of detection and accuracies are given for routine analyses

  5. High-temperature bulk acoustic wave sensors

    International Nuclear Information System (INIS)

    Fritze, Holger

    2011-01-01

    Piezoelectric crystals like langasite (La 3 Ga 5 SiO 14 , LGS) and gallium orthophosphate (GaPO 4 ) exhibit piezoelectrically excited bulk acoustic waves at temperatures of up to at least 1450 °C and 900 °C, respectively. Consequently, resonant sensors based on those materials enable new sensing approaches. Thereby, resonant high-temperature microbalances are of particular interest. They correlate very small mass changes during film deposition onto resonators or gas composition-dependent stoichiometry changes of thin films already deposited onto the resonators with the resonance frequency shift of such devices. Consequently, the objective of the work is to review the high-temperature properties, the operation limits and the measurement principles of such resonators. The electromechanical properties of high-temperature bulk acoustic wave resonators such as mechanical stiffness, piezoelectric and dielectric constant, effective viscosity and electrical conductivity are described using a one-dimensional physical model and determined accurately up to temperatures as close as possible to their ultimate limit. Insights from defect chemical models are correlated with the electromechanical properties of the resonators. Thereby, crucial properties for stable operation as a sensor under harsh conditions are identified to be the formation of oxygen vacancies and the bulk conductivity. Operation limits concerning temperature, oxygen partial pressure and water vapor pressure are given. Further, application-relevant aspects such as temperature coefficients, temperature compensation and mass sensitivity are evaluated. In addition, approximations are introduced which make the exact model handy for routine data evaluation. An equivalent electrical circuit for high-temperature resonator devices is derived based on the one-dimensional physical model. Low- and high-temperature approximations are introduced. Thereby, the structure of the equivalent circuit corresponds to the

  6. High-temperature bulk acoustic wave sensors

    Science.gov (United States)

    Fritze, Holger

    2011-01-01

    Piezoelectric crystals like langasite (La3Ga5SiO14, LGS) and gallium orthophosphate (GaPO4) exhibit piezoelectrically excited bulk acoustic waves at temperatures of up to at least 1450 °C and 900 °C, respectively. Consequently, resonant sensors based on those materials enable new sensing approaches. Thereby, resonant high-temperature microbalances are of particular interest. They correlate very small mass changes during film deposition onto resonators or gas composition-dependent stoichiometry changes of thin films already deposited onto the resonators with the resonance frequency shift of such devices. Consequently, the objective of the work is to review the high-temperature properties, the operation limits and the measurement principles of such resonators. The electromechanical properties of high-temperature bulk acoustic wave resonators such as mechanical stiffness, piezoelectric and dielectric constant, effective viscosity and electrical conductivity are described using a one-dimensional physical model and determined accurately up to temperatures as close as possible to their ultimate limit. Insights from defect chemical models are correlated with the electromechanical properties of the resonators. Thereby, crucial properties for stable operation as a sensor under harsh conditions are identified to be the formation of oxygen vacancies and the bulk conductivity. Operation limits concerning temperature, oxygen partial pressure and water vapor pressure are given. Further, application-relevant aspects such as temperature coefficients, temperature compensation and mass sensitivity are evaluated. In addition, approximations are introduced which make the exact model handy for routine data evaluation. An equivalent electrical circuit for high-temperature resonator devices is derived based on the one-dimensional physical model. Low- and high-temperature approximations are introduced. Thereby, the structure of the equivalent circuit corresponds to the Butterworth

  7. Improving the bulk data transfer experience

    Energy Technology Data Exchange (ETDEWEB)

    Guok, Chin; Guok, Chin; Lee, Jason R.; Berket, Karlo

    2008-05-07

    Scientific computations and collaborations increasingly rely on the network to provide high-speed data transfer, dissemination of results, access to instruments, support for computational steering, etc. The Energy Sciences Network is establishing a science data network to provide user driven bandwidth allocation. In a shared network environment, some reservations may not be granted due to the lack of available bandwidth on any single path. In many cases, the available bandwidth across multiple paths would be sufficient to grant the reservation. In this paper we investigate how to utilize the available bandwidth across multiple paths in the case of bulk data transfer.

  8. Forming of bulk metallic glass microcomponents

    DEFF Research Database (Denmark)

    Wert, John A.; Thomsen, Christian; Jensen, Rune Debel

    2009-01-01

    The present article considers forward extrusion, closed-die forging and backward extrusion processes for fabrication of individual microcomponents from two bulk metallic glass (BMG) compositions: Mg60Cu30Y10 and Zr44Cu40Ag8Al8. Two types of tooling were used in the present work: relatively massive...... die sets characteristic of cold forming operations for crystalline metals and lightweight die sets adapted to the special characteristics of BMGs. In addition to demonstrating that microcomponents of several geometries can be readily fabricated from BMGs, rheological properties are combined...

  9. Thulium-based bulk metallic glass

    International Nuclear Information System (INIS)

    Yu, H. B.; Yu, P.; Wang, W. H.; Bai, H. Y.

    2008-01-01

    We report the formation and properties of a thulium-based bulk metallic glass (BMG). Compared with other known rare-earth (RE) based BMGs, Tm-based BMGs show features of excellent glass formation ability, considerable higher elastic modulus, smaller Poisson's ratio, high mechanical strength, and intrinsic brittleness. The reasons for the different properties between the Tm-based and other RE-based BMGs are discussed. It is expected that the Tm-based glasses with the unique properties are appropriate candidates for studying some important issues in BMGs

  10. Fundamental study of bulk power HVDC transmission

    International Nuclear Information System (INIS)

    1981-01-01

    Study on the HVDC power transmission have been conducted since 1956. Shinshinano-Frequency Changer had been operated at first on 1977, as our home product, and Hokkaido-Honshu DC transmission also realized at 1979. Research and Development of the bulk power HVDC have been promoted by the UHV transmission special committee in our Institute from 1980. This paper is a comprehensive report published in the parts of operating control, insulation of DC line and countermeasure of fault current, and interferences in order to contribute for planning, design and operating of the UHV DC transmission in future. (author)

  11. Calculated Bulk Properties of the Actinide Metals

    DEFF Research Database (Denmark)

    Skriver, Hans Lomholt; Andersen, O. K.; Johansson, B.

    1978-01-01

    Self-consistent relativistic calculations of the electronic properties for seven actinides (Ac-Am) have been performed using the linear muffin-tin orbitals method within the atomic-sphere approximation. Exchange and correlation were included in the local spin-density scheme. The theory explains...... the variation of the atomic volume and the bulk modulus through the 5f series in terms of an increasing 5f binding up to plutonium followed by a sudden localisation (through complete spin polarisation) in americium...

  12. Multiphase composites with extremal bulk modulus

    DEFF Research Database (Denmark)

    Gibiansky, L. V.; Sigmund, Ole

    2000-01-01

    are described. Most of our new results are related to the two-dimensional problem. A numerical topology optimization procedure that solves the inverse homogenization problem is adopted and used to look for two-dimensional three-phase composites with a maximal effective bulk modulus. For the combination...... isotropic three-dimensional three-phase composites with cylindrical inclusions of arbitrary cross-sections (plane strain problem) or transversely isotropic thin plates (plane stress or bending of plates problems). (C) 2000 Elsevier Science Ltd. All rights reserved....

  13. 7 CFR 58.313 - Print and bulk packaging rooms.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Print and bulk packaging rooms. 58.313 Section 58.313 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....313 Print and bulk packaging rooms. Rooms used for packaging print or bulk butter and related products...

  14. 19 CFR 151.24 - Unlading facilities for bulk sugar.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Unlading facilities for bulk sugar. 151.24 Section... OF THE TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Sugars, Sirups, and Molasses § 151.24 Unlading facilities for bulk sugar. When dutiable sugar is to be imported in bulk, a full...

  15. Enhancement of surface magnetism due to bulk bond dilution

    International Nuclear Information System (INIS)

    Tsallis, C.; Sarmento, E.F.; Albuquerque, E.L. de

    1985-01-01

    Within a renormalization group scheme, the phase diagram of a semi-infinite simple cubic Ising ferromagnet is discussed, with arbitrary surface and bulk coupling constants, and including possible dilution of the bulk bonds. It is obtained that dilution makes easier the appearance of surface magnetism in the absence of bulk magnetism. (Author) [pt

  16. Catholic Media and Youth.

    Science.gov (United States)

    Nunes, Stephen A.

    1980-01-01

    Discusses the impact of media on youth and suggests some possible directions for the Catholic media, especially in the areas of textbooks, magazines, television, movies, and radio, in responding to the needs of youth. (Author/FM)

  17. Nurses and social media.

    Science.gov (United States)

    Farrelly, Rory

    Nurses' use of social media and other electronic communications has increased significantly with growing numbers of social media opportunities, platforms and applications including blogs, social networking sites, video sites and online chat rooms and forums.

  18. Media and Crime

    DEFF Research Database (Denmark)

    Agger, Gunhild; Waade, Anne Marit

    2011-01-01

    Recent developments in the relationship between media and crime are analyzed, taking both fiction and journalism in account......Recent developments in the relationship between media and crime are analyzed, taking both fiction and journalism in account...

  19. Development of contrast media

    International Nuclear Information System (INIS)

    Krause, W.

    1993-01-01

    Description of all contrast media (ionic and nonionic monomers, ionic and nonionic dimers) was presented. Chemotoxicity, osmolality and viscosity of some contrast agents were analyzed. The main adverse reactions to ionic and nonionic contrast media were described

  20. The social media revolution.

    Science.gov (United States)

    Dubose, Cheryl

    2011-01-01

    The growing popularity and use of social media tools such as Facebook, YouTube, Twitter, blogging, and wikis have led to a social media revolution. Given this widespread influence, it is important for educators, administrators, and technologists to understand the risks of using social media in the classroom and workplace. To investigate popular social media sites and their effect on radiologic technology education and business practices. A comprehensive search of literature was performed to examine social media and its applications in education, health care, and business. Social media use is on the rise, affecting all aspects of mainstream society. Leaders in the radiologic sciences should be familiar with social media and cognizant of its risks. Future studies regarding social media use in the radiologic sciences are necessary to determine its effect on the radiologic science community. ©2011 by the American Society of Radiologic Technologists.

  1. MODERN MEDIA EDUCATION MODELS

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2011-03-01

    Full Text Available The author supposed that media education models can be divided into the following groups:- educational-information models (the study of the theory, history, language of media culture, etc., based on the cultural, aesthetic, semiotic, socio-cultural theories of media education;- educational-ethical models (the study of moral, religions, philosophical problems relying on the ethic, religious, ideological, ecological, protectionist theories of media education;- pragmatic models (practical media technology training, based on the uses and gratifications and ‘practical’ theories of media education;- aesthetical models (aimed above all at the development of the artistic taste and enriching the skills of analysis of the best media culture examples. Relies on the aesthetical (art and cultural studies theory; - socio-cultural models (socio-cultural development of a creative personality as to the perception, imagination, visual memory, interpretation analysis, autonomic critical thinking, relying on the cultural studies, semiotic, ethic models of media education.

  2. Use of containers to carry bulk and break bulk commodities and its impact on gulf region ports and international trade.

    Science.gov (United States)

    2014-08-01

    The University of New Orleans Transportation Institute was tasked by the Louisiana Transportation Research Center (LTRC) in mid-2012 to assess the use of containers to transport bulk and break bulk commodities and to determine what their impact would...

  3. Asian Media Productions

    DEFF Research Database (Denmark)

    This work consists of 12 essays on different aspects of Asian media by Japanese, European, and American scholars, many of whom have themselves been involved in the production of media forms. Working in the fields of anthropology, media and cultural studies, and on the basis of hands-on research, ......, they have written a book on the social practices and cultural attitudes of people producing, reading, watching and listening to different kinds of media in Japan, China, Taiwan, Indonesia, Vietnam, Singapore and India....

  4. Advertising on social media

    OpenAIRE

    Sumit Goyal

    2013-01-01

    This communication reports the latest trends of advertising on social media. Social media advertising means to gain traffic or attention of online users through social media sites. Today, when a user thinks about buying something, he first comes to the internet, searches for that product, compares its price with other competing brands and takes a decision, which one to buy. In this write-up, author has discussed many aspects concerning advertising through social media, viz., what is social me...

  5. Procedural Media Representation

    OpenAIRE

    Henrysson, Anders

    2002-01-01

    We present a concept for using procedural techniques to represent media. Procedural methods allow us to represent digital media (2D images, 3D environments etc.) with very little information and to render it photo realistically. Since not all kind of content can be created procedurally, traditional media representations (bitmaps, polygons etc.) must be used as well. We have adopted an object-based media representation where an object can be represented either with a procedure or with its trad...

  6. Elastic properties of superconducting bulk metallic glasses

    International Nuclear Information System (INIS)

    Hempel, Marius

    2015-01-01

    Within the framework of this thesis the elastic properties of a superconducting bulk metallic glass between 10 mK and 300 K were first investigated. In order to measure the entire temperature range, in particular the low temperature part, new experimental techniques were developed. Using an inductive readout scheme for a double paddle oscillator it was possible to determine the internal friction and the relative change of sound velocity of bulk metallic glasses with high precision. This allowed for a detailed comparison of the data with different models. The analysis focuses on the low temperature regime where the properties of glassy materials are governed by atomic tunneling systems as described by the tunneling model. The influence of conduction electrons in the normal conducting state and quasiparticles in the superconducting state of the glass were accounted for in the theoretical description, resulting in a good agreement over a large temperature range between measured data and prediction of the tunneling model. This allowed for a direct determination of the coupling constant between electrons and tunneling systems. In the vicinity of the transition temperature Tc the data can only be described if a modified distribution function of the tunneling parameters is applied.

  7. Boundary-bulk relation in topological orders

    Directory of Open Access Journals (Sweden)

    Liang Kong

    2017-09-01

    Full Text Available In this paper, we study the relation between an anomaly-free n+1D topological order, which are often called n+1D topological order in physics literature, and its nD gapped boundary phases. We argue that the n+1D bulk anomaly-free topological order for a given nD gapped boundary phase is unique. This uniqueness defines the notion of the “bulk” for a given gapped boundary phase. In this paper, we show that the n+1D “bulk” phase is given by the “center” of the nD boundary phase. In other words, the geometric notion of the “bulk” corresponds precisely to the algebraic notion of the “center”. We achieve this by first introducing the notion of a morphism between two (potentially anomalous topological orders of the same dimension, then proving that the notion of the “bulk” satisfies the same universal property as that of the “center” of an algebra in mathematics, i.e. “bulk = center”. The entire argument does not require us to know the precise mathematical description of a (potentially anomalous topological order. This result leads to concrete physical predictions.

  8. Bulk delivery of explosives offers positive advantages

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-09-01

    The bulk delivery of precisely-formulated explosives directly to the shothole is a safe, secure and cost effective way of bringing rock to the quarry floor. This article describes several of the latest generation of Anfo trucks. The typical Anfo truck carries ammonium nitrate and fuel oil in bulk, together with several other mix constituents, including an emulsifying agent. These are designed to form the basis of a range of emulsion-type explosives. In effect, these are water in oil emulsions where the water phase consists of droplets of a saturated solution of the oxidizing material suspended in oil. The formulations may be further tailored to the shothole requirements by the addition of oils or waxes, which can alter the viscosity of the explosive. The precise and programmable controls which determine the exact quantities of materials delivered to the mixer mean that the explosive mixtures can be tailored exactly to the requirements of the blasting operation, be it the amount of rock to be dislodged, the geological conditions, or the state of the shothole - either wet or dry. 4 systems are described in detail. 3 figs.

  9. Perovskite oxides: Oxygen electrocatalysis and bulk structure

    Science.gov (United States)

    Carbonio, R. E.; Fierro, C.; Tryk, D.; Scherson, D.; Yeager, Ernest

    1987-01-01

    Perovskite type oxides were considered for use as oxygen reduction and generation electrocatalysts in alkaline electrolytes. Perovskite stability and electrocatalytic activity are studied along with possible relationships of the latter with the bulk solid state properties. A series of compounds of the type LaFe(x)Ni1(-x)O3 was used as a model system to gain information on the possible relationships between surface catalytic activity and bulk structure. Hydrogen peroxide decomposition rate constants were measured for these compounds. Ex situ Mossbauer effect spectroscopy (MES), and magnetic susceptibility measurements were used to study the solid state properties. X ray photoelectron spectroscopy (XPS) was used to examine the surface. MES has indicated the presence of a paramagnetic to magnetically ordered phase transition for values of x between 0.4 and 0.5. A correlation was found between the values of the MES isomer shift and the catalytic activity for peroxide decomposition. Thus, the catalytic activity can be correlated to the d-electron density for the transition metal cations.

  10. Media Education: Sociology Surveys

    Science.gov (United States)

    Fedorov, Alexander

    2007-01-01

    In Russia as well as in foreign countries we can witness sort of the confusion of the terms of "media education" and "media literacy". There are quite a few differences in theoretical approaches to media education, to distinguishing of the most important aims, objectives, means of introduction into the teaching process, etc.…

  11. Modern Media Education Models

    Science.gov (United States)

    Fedorov, Alexander

    2011-01-01

    The author supposed that media education models can be divided into the following groups: (1) educational-information models (the study of the theory, history, language of media culture, etc.), based on the cultural, aesthetic, semiotic, socio-cultural theories of media education; (2) educational-ethical models (the study of moral, religions,…

  12. Open Media Science

    DEFF Research Database (Denmark)

    Martiny, Kristian Møller Moltke; Pedersen, David Budtz; Hansted, Alfred Birkegaard

    2016-01-01

    and extend into a fully-fledged Open Media movement engaging with new media and non-traditional formats of science communication. We discuss two cases where experiments with open media have driven new collaborations between scientists and documentarists. We use the cases to illustrate different advantages...

  13. Children's Media Policy

    Science.gov (United States)

    Jordan, Amy B.

    2008-01-01

    Amy Jordan addresses the need to balance the media industry's potentially important contributions to the healthy development of America's children against the consequences of excessive and age-inappropriate media exposure. Much of the philosophical tension regarding how much say the government should have about media content and delivery stems…

  14. Social Media Empowerment (I)

    NARCIS (Netherlands)

    A. Cox

    2011-01-01

    full text via link. Social media stellen mensen, merken en bedrijven in staat om zichzelf te versterken. Soms wordt optimaal gebruik gemaakt van Social Media Empowerment, maar soms ook wat minder. Effectief inzetten van social media. Regel 1: Start met context en motivatie

  15. Youth media lifestyles

    NARCIS (Netherlands)

    van Kruistum, Claudia; Leseman, Paul Pm; de Haan, Mariëtte

    2014-01-01

    In this article, the concept of "media lifestyles" is adopted in order to develop a comprehensive approach toward youth engagement in communication media. We explore how 503 Dutch eighth grade students with full access to new technology combine a broad range of media by focusing on their engagement

  16. Sizing Up Social Media

    Science.gov (United States)

    Pearson, Jerold

    2010-01-01

    Most people are aware of the increasing importance of social media to institutional advancement, and many colleges and universities have started investing resources in these media. The next step is to measure the impact of social media on the institution and evaluate the success of one's efforts. Every advancement leader should understand how…

  17. The Media Reader.

    Science.gov (United States)

    Valdes, Joan; Crow, Jeanne

    An anthology of readings in the media correlates chapter-by-chapter to the authors' textbook, "The Media Works." Fifteen chapters cover the study of newspapers, magazines, comics, popular music, television, movies, and advertising. The authors included represent varied perspectives on the media. The selections were chosen with the help of a…

  18. Media and child development

    NARCIS (Netherlands)

    Piotrowski, J.T.; Vossen, H.G.M.; Valkenburg, P.M.; Wright, J.D.

    2015-01-01

    Decades of research have shown that the relationship between media and childhood is not unidirectional but reciprocal. In this article, both directions of the media-child development relationship are presented. We discuss how child development predisposes children's media use and preferences by

  19. 78 FR 72841 - List of Bulk Drug Substances That May Be Used in Pharmacy Compounding; Bulk Drug Substances That...

    Science.gov (United States)

    2013-12-04

    .... FDA-2013-N-1525] List of Bulk Drug Substances That May Be Used in Pharmacy Compounding; Bulk Drug... proposed rule to list bulk drug substances used in pharmacy compounding and preparing to develop a list of... Formulary monograph, if a monograph exists, and the United States Pharmacopoeia chapter on pharmacy...

  20. Incidence of Listeria species in bovine, ovine, caprine, camel and water buffalo milk using cultural method and the PCR assay

    OpenAIRE

    Rahimi, Ebrahim; Momtaz, Hassan; Behzadnia, Asma; Baghbadorani, Zeinab Torki

    2014-01-01

    Objective: To determine the prevalence rate of Listeria species in bovine, ovine, caprine, camel and water buffalo milk in Iran. Methods: From September 2010 to December 2011 a total of 260 bulk milk samples including 85 bovine, 37 camel, 34 water buffalo, 56 ovine and 48 caprine bulk milk samples were collected from commercial dairy herds, in Fars and Khuzestan provinces, Iran and were evaluated for the presence of Listeria species using cultural method and the PCR assay. R...

  1. Determination of thymidine in serum used for cell culture media

    International Nuclear Information System (INIS)

    Schaer, J.C.; Maurer, U.; Schindler, R.

    1978-01-01

    Thymidine concentrations in serum used for cell culture media were determined with an assay based on isotope dilution. In this assay, incorporation of (3H)-thymidine into DNA of cultured cells was measured in the presence of 5 and 20% serum as a function of the concentration of unlabeled thymidine added to the medium. Thymidine concentrations were measured using horse serum as well as fetal calf serum in the culture media. Dialysis of serum resulted in a reduction of thymidine levels by factors of at least 10

  2. Assaying Cellular Viability Using the Neutral Red Uptake Assay.

    Science.gov (United States)

    Ates, Gamze; Vanhaecke, Tamara; Rogiers, Vera; Rodrigues, Robim M

    2017-01-01

    The neutral red uptake assay is a cell viability assay that allows in vitro quantification of xenobiotic-induced cytotoxicity. The assay relies on the ability of living cells to incorporate and bind neutral red, a weak cationic dye, in lysosomes. As such, cytotoxicity is expressed as a concentration-dependent reduction of the uptake of neutral red after exposure to the xenobiotic under investigation. The neutral red uptake assay is mainly used for hazard assessment in in vitro toxicology applications. This method has also been introduced in regulatory recommendations as part of 3T3-NRU-phototoxicity-assay, which was regulatory accepted in all EU member states in 2000 and in the OECD member states in 2004 as a test guideline (TG 432). The present protocol describes the neutral red uptake assay using the human hepatoma cell line HepG2, which is often employed as an alternative in vitro model for human hepatocytes. As an example, the cytotoxicity of acetaminophen and acetyl salicylic acid is assessed.

  3. Stability-indicating HPLC determination of pramipexole dihydrochloride in bulk drug and pharmaceutical dosage form

    OpenAIRE

    Panditrao, Vedavati M; Sarkate, Aniket P; Sangshetti, Jaiprakash N; Wakte, Pravin S; Shinde, Devanand B

    2011-01-01

    A novel stability-indicating high-performance liquid chromatographic assay method was developed and validated for quantitative determination of pramipexole dihydrochloride in bulk drugs and in pharmaceutical dosage form in the presence of degradation products. An isocratic, reversed phase HPLC method was developed to separate the drug from the degradation products, using an Ace5-C18 (250×4.6 mm, 5 µm) advance chromatography column, and 10 mmol L-1 ammonium acetate and acetonitrile (75:25 v/v)...

  4. Bulk forming of industrial micro components in conventional metals and bulk metallic glasses

    DEFF Research Database (Denmark)

    Arentoft, Mogens; Paldan, Nikolas Aulin; Eriksen, Rasmus Solmer

    2007-01-01

    For production of micro components in large numbers, forging is an interesting and challenging process. The conventional metals like silver, steel and aluminum often require multi-step processes, but high productivity and increased strength justify the investment. As an alternative, bulk metallic...

  5. Notes for media reinvention

    Directory of Open Access Journals (Sweden)

    Jesús Miguel Flores-Vivar

    2009-10-01

    Full Text Available Journalism and media are going through a change of era. This change is reflected in the transformation of journalism and media-lived and that another major in 1980 that became known as mediamorphosis, by this, professionals have to learn new roles. The impact of information technology and Internet has changed the way how you present the news and, most importantly, transform the business model that has characterized media companies. This article analyzes the current situation provides some strategic guidelines to be followed by some media-and-do and studied some of the new profiles arebeginning to emerge as a result of the reinvention of journalism and the media.

  6. Prosocial effects of media.

    Science.gov (United States)

    Hogan, Marjorie J

    2012-06-01

    Parents, teachers, health care providers, and other caring adults worry about the harmful influence of media messages and images on children and teens and wonder how to recognize and encourage positive and healthy use of media. For decades, experts have commented on the power of media. Media depictions can lead to negative attitudes and behavior in some young viewers. This article discusses whether prosocial, tolerant, and cooperative attitudes and behavior can be learned and imitated by children and adolescents and whether media can nurture or stimulate creativity or actively promote health and well-being in young consumers. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Thermal characterization of semiconducting polymer bulk heterojunctions

    Science.gov (United States)

    Remy, Roddel A.

    Polymer semiconductors are intriguing due to their potential use in flexible electronics. Poly (3-hexylthiophene) (P3HT)--a very common polymer in this field--is semicrystalline and it is known that crystalline P3HT has a higher hole mobility than amorphous P3HT. Quantifying each fraction in the bulk and thin film states is therefore crucial to understanding its performance in transistor and other applications. In polymer solar cells, it acts as an electron donor and is typically mixed with the nanoparticle-like molecule, phenyl-C61-butyric acid methyl ester (PCBM)--an electron acceptor--in a thin film morphology termed a bulk heterojunction (BHJ). The structural hierarchy within the bulk heterojunction is complicated and its characterization, with a focus on P3HT morphology, is the topic of this dissertation. Calorimetry can play an important role in the elucidation of P3HT morphology with quantitative analysis of the crystalline and amorphous fractions present in the material. This was demonstrated by employing differential scanning calorimetry (DSC) to obtain the enthalpy of fusion of 100% crystalline P3HT (42.9 J/g) using oligomeric P3HT measurements. The more sensitive temperature modulated DSC (TMDSC) was then used to examine the glass transition of P3HT and the crystalline, mobile amorphous and rigid amorphous phases were quantified. The presence of these phases can play a large role in understanding the charge transfer process in polymer semiconductors. BHJ thin films of 50 wt.% PCBM were then analyzed and a polymer crystallinity of 30% was found after thermal annealing from initially non-crystalline polymer material. With assistance from previously acquired small angle neutron scattering data, a thorough analysis of the entire BHJ morphology was accomplished. A surprisingly large rigid amorphous polymer phase is present in the BHJ which could be located at the P3HT/PCBM interface, affecting charge transfer. Finally, interlayer diffusion of PCBM was

  8. Radiation effects in bulk and nanostructured silicon

    Energy Technology Data Exchange (ETDEWEB)

    Holmstrom, E.

    2012-07-01

    Understanding radiation effects in silicon (Si) is of great technological importance. The material, being the basis of modern semiconductor electronics and photonics, is subjected to radiation already at the processing stage, and in many applications throughout the lifetime of the manufactured component. Despite decades of research, many fundamental questions on the subject are still not satisfactorily answered, and new ones arise constantly as device fabrication shifts towards the nanoscale. In this study, methods of computational physics are harnessed to tackle basic questions on the radiation response of bulk and nanostructured Si systems, as well as to explain atomic-scale phenomena underlying existing experimental results. Empirical potentials and quantum mechanical models are coupled with molecular dynamics simulations to model the response of Si to irradiation and to characterize the created crystal damage. The threshold displacement energy, i.e., the smallest recoil energy required to create a lattice defect, is determined in Si bulk and nanowires, in the latter system also as a function of mechanical strain. It is found that commonly used values for this quantity are drastically underestimated. Strain on the nanowire causes the threshold energy to drop, with an effect on defect production that is significantly higher than in an another nanostructure with similar dimensions, the carbon nanotube. Simulating ion irradiation of Si nanowires reveals that the large surface area to volume ratio of the nanostructure causes up to a three-fold enhancement in defect production as compared to bulk Si. Amorphous defect clusters created by energetic neutron bombardment are predicted, on the basis of their electronic structure and abundance, to cause a deleterious phenomenon called type inversion in Si strip detectors in high-energy physics experiments. The thinning of Si lamellae using a focused ion beam is studied in conjunction with experiment to unravel the cause for

  9. Comprehension of digital media

    International Nuclear Information System (INIS)

    Kim, Ju Hwan

    2008-11-01

    This book is divided four parts. The first part describes media and mark on sign and media, what is the sign?, interpretation of sign and semiotics. The second part is for production sign theory and origin of digital revolution such as the problem of origin of digital revolution, homogeneity of producing goods and sign : triple triangle model for production sign theory, triple triangle model for producing goods, triple triangle model of producing sign and triple triangle model of art works. The third parts deals with development of the media and meaning of digital revolution with four changes : invention of letter, appearance of printed media and establishment modernity, appearance electronic media and mess media and appearance of digital media. The last part mentions ontology of world wide web.

  10. The Media Mixer

    DEFF Research Database (Denmark)

    Vestergaard, Vitus; Mortensen, Christian Hviid

    2011-01-01

    content. The media content is created by the user in the museum's physical environment, but it can be mixed with material from web archives. It is the intention that the users learn about media through participatory and creative processes with media where the borders between producing, playing......We explore how remixing and content sharing can be used as a means for user participation in a digital museum age. Remix culture is seen as a culture that allows and encourages the production of derivative works; works that are based on already existing works. This cultural practice thrives...... throughout the Internet, most notably on web 2.0 sites like YouTube. The Media Museum has embraced the remix paradigm with the development of an interactive media experience centre called the Media Mixer. Here the museum users can produce, deconstruct, reconstruct and finally publish and share digital media...

  11. Radiographic contrast media

    International Nuclear Information System (INIS)

    Golman, K.; Holtz, E.; Almen, T.

    1987-01-01

    Contrast media are used in diagnostic radiology to enhance the X-ray attenuation between a body structure of interest and the surrounding tissue. A detail becomes perceptible on a roentgenogram only when its contrast exceeds a minimum value in relation to the background. Small areas of interest must have higher contrast than the background. The contrast effect depends on concentration of the contrast media with the body. A high contrast media concentration difference thus gives rise to more morphological details in the radiographs. Contrast media can be divided into negative contrast media such as air and gas which attenuate X-rays less than the body tissues, and positive contrast materials which attenuate X-rays more than the body tissues. The positive contrast media all contain either iodine (atomic number 53) or barium (atomic number 56) and can be divided into water-insoluble and water-soluble contrast media

  12. Comprehension of digital media

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ju Hwan

    2008-11-15

    This book is divided four parts. The first part describes media and mark on sign and media, what is the sign?, interpretation of sign and semiotics. The second part is for production sign theory and origin of digital revolution such as the problem of origin of digital revolution, homogeneity of producing goods and sign : triple triangle model for production sign theory, triple triangle model for producing goods, triple triangle model of producing sign and triple triangle model of art works. The third parts deals with development of the media and meaning of digital revolution with four changes : invention of letter, appearance of printed media and establishment modernity, appearance electronic media and mess media and appearance of digital media. The last part mentions ontology of world wide web.

  13. The fluorometric microculture cytotoxicity assay.

    Science.gov (United States)

    Lindhagen, Elin; Nygren, Peter; Larsson, Rolf

    2008-01-01

    The fluorometric microculture cytotoxicity assay (FMCA) is a nonclonogenic microplate-based cell viability assay used for measurement of the cytotoxic and/or cytostatic effect of different compounds in vitro. The assay is based on hydrolysis of the probe, fluorescein diacetate (FDA) by esterases in cells with intact plasma membranes. The assay is available as both a semiautomated 96-well plate setup and a 384-well plate version fully adaptable to robotics. Experimental plates are prepared with a small amount of drug solution and can be stored frozen. Cells are seeded on the plates and cell viability is evaluated after 72 h. The protocol described here is applicable both for cell lines and freshly prepared tumor cells from patients and is suitable both for screening in drug development and as a basis for a predictive test for individualization of anticancer drug therapy.

  14. Solution assay instrument operations manual

    International Nuclear Information System (INIS)

    Li, T.K.; Marks, T.; Parker, J.L.

    1983-09-01

    An at-line solution assay instrument (SAI) has been developed and installed in a plutonium purification and americium recovery process area in the Los Alamos Plutonium Processing Facility. The instrument was designed for accurate, timely, and simultaneous nondestructive analysis of plutonium and americium in process solutions that have a wide range of concentrations and americium/plutonium ratios and for routine operation by process technicians who lack instrumentation background. The SAI, based on transmission-corrected, high-resolution gamma-ray spectroscopy, has two measurement stations attached to a single multichannel analyzer/computer system. To ensure the quality of assay results, the SAI has an internal measurement control program, which requires daily and weekly check runs and monitors key aspects of all assay runs. For a 25-ml sample, the assay precision is 5 g/l within a 2000-s count time

  15. Fusion, collapse, and stationary bound states of incoherently coupled waves in bulk cubic media

    DEFF Research Database (Denmark)

    Bang, Ole; Bergé, L.; Juul Rasmussen, Jens

    1999-01-01

    these sufficient conditions numerically and show that only when the equations and the initial conditions are symmetric are they also close to bring necessary conditions. Using Gaussian initial conditions we predict and confirm numerically the power dependent characteristic initial separations that divide the phase...

  16. Media:Time card stack

    NARCIS (Netherlands)

    Annemarie Wennekers; Jos de Haan; Frank Huysmans

    2016-01-01

    Original title: Media:Tijd in kaart The Dutch spend a daily average of 8 hours 33 minutes using media. Men and people aged over 50 spend most time using media, at an average of 9 hours per day. Older media users prefer traditional media and devices over new media and modern devices. Young and

  17. Radioligand assay in reproductive biology

    International Nuclear Information System (INIS)

    Korenman, S.G.; Sherman, B.M.

    1975-01-01

    Radioligand assays have been developed for the principal reproductive steroids and peptide hormones. Specific binding reagents have included antibodies, plasma binders, and intracellular receptors. In each assay, problems of specificity, sensitivity, and nonspecific inhibitors were encountered. Many features of the endocrine physiology in childhood, during puberty, and in adulthood have been characterized. Hormonal evaluations of endocrine disorders of reproduction are characterized on the basis of their characteristic pathophysiologic alterations. (U.S.)

  18. Understanding Social Media Logic

    Directory of Open Access Journals (Sweden)

    José van Dijck

    2013-08-01

    Full Text Available Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions and rules of social interaction. In this article, we examine the intricate dynamic between social media platforms, mass media, users, and social institutions by calling attention to social media logic—the norms, strategies, mechanisms, and economies—underpin­ning its dynamics. This logic will be considered in light of what has been identified as mass me­dia logic, which has helped spread the media's powerful discourse outside its institutional boundaries. Theorizing social media logic, we identify four grounding principles—programmabil­ity, popularity, connectivity, and datafication—and argue that these principles become increas­ingly entangled with mass media logic. The logic of social media, rooted in these grounding principles and strategies, is gradually invading all areas of public life. Besides print news and broadcasting, it also affects law and order, social activism, politics, and so forth. Therefore, its sustaining logic and widespread dissemination deserve to be scrutinized in detail in order to better understand its impact in various domains. Concentrating on the tactics and strategies at work in social media logic, we reassess the constellation of power relationships in which social practices unfold, raising questions such as: How does social media logic modify or enhance ex­isting mass media logic? And how is this new media logic exported beyond the boundaries of (social or mass media proper? The underlying principles, tactics, and strategies may be relat­ively simple to identify, but it is much harder to map the complex connections between plat­forms that distribute this logic: users that employ them, technologies that

  19. Transformation of bulk alloys to oxide nanowires

    Science.gov (United States)

    Lei, Danni; Benson, Jim; Magasinski, Alexandre; Berdichevsky, Gene; Yushin, Gleb

    2017-01-01

    One dimensional (1D) nanostructures offer prospects for enhancing the electrical, thermal, and mechanical properties of a broad range of functional materials and composites, but their synthesis methods are typically elaborate and expensive. We demonstrate a direct transformation of bulk materials into nanowires under ambient conditions without the use of catalysts or any external stimuli. The nanowires form via minimization of strain energy at the boundary of a chemical reaction front. We show the transformation of multimicrometer-sized particles of aluminum or magnesium alloys into alkoxide nanowires of tunable dimensions, which are converted into oxide nanowires upon heating in air. Fabricated separators based on aluminum oxide nanowires enhanced the safety and rate capabilities of lithium-ion batteries. The reported approach allows ultralow-cost scalable synthesis of 1D materials and membranes.

  20. Organic hybrid planar-nanocrystalline bulk heterojunctions

    Science.gov (United States)

    Forrest, Stephen R [Ann Arbor, MI; Yang, Fan [Piscataway, NJ

    2011-03-01

    A photosensitive optoelectronic device having an improved hybrid planar bulk heterojunction includes a plurality of photoconductive materials disposed between the anode and the cathode. The photoconductive materials include a first continuous layer of donor material and a second continuous layer of acceptor material. A first network of donor material or materials extends from the first continuous layer toward the second continuous layer, providing continuous pathways for conduction of holes to the first continuous layer. A second network of acceptor material or materials extends from the second continuous layer toward the first continuous layer, providing continuous pathways for conduction of electrons to the second continuous layer. The first network and the second network are interlaced with each other. At least one other photoconductive material is interspersed between the interlaced networks. This other photoconductive material or materials has an absorption spectra different from the donor and acceptor materials.

  1. Bulk nanoscale materials in steel products

    International Nuclear Information System (INIS)

    Chehab, B; Wang, X; Masse, J-P; Zurob, H; Embury, D; Bouaziz, O

    2010-01-01

    Although a number of nanoscale metallic materials exhibit interesting mechanical properties the fabrication paths are often complex and difficult to apply to bulk structural materials. However a number of steels which exhibit combinations of plasticity and phase transitions can be deformed to produce ultra high strength levels in the range 1 to 3 GPa. The resultant high stored energy and complex microstructures allow new nanoscale structures to be produced by combinations of recovery and recrystallisation. The resultant structures exhibit totally new combinations of strength and ductility to be achieved. In specific cases this also enables both the nature of the grain boundary structure and the spatial variation in structure to be controlled. In this presentation both the detailed microstructural features and their relation to the strength, work-hardening capacity and ductility will be discussed for a number of martensitic and austenitic steels.

  2. Tuneable film bulk acoustic wave resonators

    CERN Document Server

    Gevorgian, Spartak Sh; Vorobiev, Andrei K

    2013-01-01

    To handle many standards and ever increasing bandwidth requirements, large number of filters and switches are used in transceivers of modern wireless communications systems. It makes the cost, performance, form factor, and power consumption of these systems, including cellular phones, critical issues. At present, the fixed frequency filter banks based on Film Bulk Acoustic Resonators (FBAR) are regarded as one of the most promising technologies to address performance -form factor-cost issues. Even though the FBARs improve the overall performances the complexity of these systems remains high.  Attempts are being made to exclude some of the filters by bringing the digital signal processing (including channel selection) as close to the antennas as possible. However handling the increased interference levels is unrealistic for low-cost battery operated radios. Replacing fixed frequency filter banks by one tuneable filter is the most desired and widely considered scenario. As an example, development of the softwa...

  3. Criticality in Bulk Metallic Glass Constituent Elements

    Science.gov (United States)

    Mota, Rodrigo Miguel Ojeda; Graedel, T. E.; Pekarskaya, Evgenia; Schroers, Jan

    2017-11-01

    Bulk metallic glasses (BMGs), which readily form amorphous phases during solidification, are increasingly being used in first applications of watch components, electronic casings, and sporting goods. The compositions of BMGs typically include four to six elements. Various political and geological factors have recently led to supply disruptions for several metals, including some present in BMG compositions. In this work, we assess the "criticality" of 22 technologically interesting BMG compositions, compare the results with those for three common engineering alloy groups, and derive recommendations for BMG composition choices from a criticality perspective. The criticality of BMGs is found to be generally much higher compared with those for the established engineering alloys. Therefore, criticality concerns should also be considered in the choice between existing and developing novel BMGs.

  4. Solid state properties from bulk to nano

    CERN Document Server

    Dresselhaus, Mildred; Cronin, Stephen; Gomes Souza Filho, Antonio

    2018-01-01

    This book fills a gap between many of the basic solid state physics and materials science books that are currently available. It is written for a mixed audience of electrical engineering and applied physics students who have some knowledge of elementary undergraduate quantum mechanics and statistical mechanics. This book, based on a successful course taught at MIT, is divided pedagogically into three parts: (I) Electronic Structure, (II) Transport Properties, and (III) Optical Properties. Each topic is explained in the context of bulk materials and then extended to low-dimensional materials where applicable. Problem sets review the content of each chapter to help students to understand the material described in each of the chapters more deeply and to prepare them to master the next chapters.

  5. A route to transparent bulk metals

    KAUST Repository

    Schwingenschlögl, Udo

    2012-07-23

    Hypothetical compounds based on a sapphire host are investigated with respect to their structural as well as electronic features. The results are obtained by electronic structure calculations within density functional theory and the generalized gradient approximation. A quarter of the Al atoms in Al 2O 3 is replaced by a 4d transition metal M ion, with d 0 to d 9 electronic configuration. We perform structure optimizations for all the compounds and analyze the electronic states. Due to the sizeable band gap of the Al 2O 3 host, we can identify promising candidates for transparent bulk metals. We explain the mechanisms leading to this combination of materials properties. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Mechanical reliability of bulk high Tc superconductors

    International Nuclear Information System (INIS)

    Freiman, S.W.

    1990-01-01

    Most prospective applications for high T c superconductors in bulk form, e.g. magnets, motors, will require appreciable mechanical strength. Work at NIST [National Institute of Standards and Technology] has begun to address issues related to mechanical reliability. For example, recent studies on Ba-Y-Cu-O have shown that the intrinsic crack growth resistance, K IC , of crystals of this material is even smaller than was first reported, less than that of window glass, and is sensitive to moisture. Processing conditions, particularly sintering and annealing atmosphere, have been shown to have a major influence on microstructure and internal stresses in the material. Large internal stresses result from the tetragonal to orthorhombic phase transformation as well as the thermal expansion anisotropy in the grains of the ceramic. Because stress relief is absent, microcracks form which have a profound influence on strength

  7. On bulk viscosity and moduli decay

    International Nuclear Information System (INIS)

    Laine, Mikko

    2010-01-01

    This pedagogically intended lecture, one of four under the header 'Basics of thermal QCD', reviews an interesting relationship, originally pointed out by Boedeker, that exists between the bulk viscosity of Yang-Mills theory (of possible relevance to the hydrodynamics of heavy ion collision experiments) and the decay rate of scalar fields coupled very weakly to a heat bath (appearing in some particle physics inspired cosmological scenarios). This topic serves, furthermore, as a platform on which a number of generic thermal field theory concepts are illustrated. The other three lectures (on the QCD equation of state and the rates of elastic as well as inelastic processes experienced by heavy quarks) are recapitulated in brief encyclopedic form. (author)

  8. Bulk disk resonator based ultrasensitive mass sensor

    DEFF Research Database (Denmark)

    Cagliani, Alberto; Davis, Zachary James

    2009-01-01

    range. The sensor has been characterized in terms of sensitivity both for distributed mass detection, performing six consecutive depositions of e-beam evaporated Au, and localized mass detection, depositing approximately 7.5 pg of Pt/Ga/C three times consecutively with a Focused Ion Beam system......In the framework of developing an innovative label-free sensor for multiarrayed biodetection applications, we present a novel bulk resonator based mass sensor. The sensor is a polysilicon disk which shows a Q-factor of 6400 in air at 68.8 MHz, resulting in mass resolutions down in the femtogram....... The sensor has an extremely high distributed mass to frequency shift sensitivity of 60104 Hzcm2/¿g and shows a localized mass to frequency sensitivity up to 4405 Hz/pg with a localized mass resolution down to 15 fg. The device has been fabricated with a new microfabrication process that uses only two...

  9. Single-cell nanotoxicity assays of superparamagnetic iron oxide nanoparticles.

    Science.gov (United States)

    Eustaquio, Trisha; Leary, James F

    2012-01-01

    Properly evaluating the nanotoxicity of nanoparticles involves much more than bulk-cell assays of cell death by necrosis. Cells exposed to nanoparticles may undergo repairable oxidative stress and DNA damage or be induced into apoptosis. Exposure to nanoparticles may cause the cells to alter their proliferation or differentiation or their cell-cell signaling with neighboring cells in a tissue. Nanoparticles are usually more toxic to some cell subpopulations than others, and toxicity often varies with cell cycle. All of these facts dictate that any nanotoxicity assay must be at the single-cell level and must try whenever feasible and reasonable to include many of these other factors. Focusing on one type of quantitative measure of nanotoxicity, we describe flow and scanning image cytometry approaches to measuring nanotoxicity at the single-cell level by using a commonly used assay for distinguishing between necrotic and apoptotic causes of cell death by one type of nanoparticle. Flow cytometry is fast and quantitative, provided that the cells can be prepared into a single-cell suspension for analysis. But when cells cannot be put into suspension without altering nanotoxicity results, or if morphology, attachment, and stain location are important, a scanning image cytometry approach must be used. Both methods are described with application to a particular type of nanoparticle, a superparamagnetic iron oxide nanoparticle (SPION), as an example of how these assays may be applied to the more general problem of determining the effects of nanomaterial exposure to living cells.

  10. Locality, bulk equations of motion and the conformal bootstrap

    Energy Technology Data Exchange (ETDEWEB)

    Kabat, Daniel [Department of Physics and Astronomy, Lehman College, City University of New York,250 Bedford Park Blvd. W, Bronx NY 10468 (United States); Lifschytz, Gilad [Department of Mathematics, Faculty of Natural Science, University of Haifa,199 Aba Khoushy Ave., Haifa 31905 (Israel)

    2016-10-18

    We develop an approach to construct local bulk operators in a CFT to order 1/N{sup 2}. Since 4-point functions are not fixed by conformal invariance we use the OPE to categorize possible forms for a bulk operator. Using previous results on 3-point functions we construct a local bulk operator in each OPE channel. We then impose the condition that the bulk operators constructed in different channels agree, and hence give rise to a well-defined bulk operator. We refer to this condition as the “bulk bootstrap.” We argue and explicitly show in some examples that the bulk bootstrap leads to some of the same results as the regular conformal bootstrap. In fact the bulk bootstrap provides an easier way to determine some CFT data, since it does not require knowing the form of the conformal blocks. This analysis clarifies previous results on the relation between bulk locality and the bootstrap for theories with a 1/N expansion, and it identifies a simple and direct way in which OPE coefficients and anomalous dimensions determine the bulk equations of motion to order 1/N{sup 2}.

  11. A radiobiological comparison of human tumor soft-agar clonogenic assays.

    Science.gov (United States)

    West, C M; Sutherland, R M

    1986-06-15

    Radiation survival curves have been generated for 3 human tumor cell lines as a means of comparing and evaluating the validity of human tumor soft-agar clonogenic assays. The assays investigated were the Hamburger-Salmon, Courtenay-Mills, Courtenay-Mills plus additions, soft agar (no additions), and soft agar plus additions. The additions were formulated to supplement the media used in soft agar assays of primary ovarian and cervical carcinoma specimens. Supplementing the media with additions led to a 2- to 3-fold increase in PE of CaSki cells but had no effect on the PEs of ME180 and OWI cells. Radiation survival curves were similar in all assays for CaSki and OWI but differed for ME180 cells. For ME180 cells, the Courtenay-Mills and soft agar assays plus additions produced the most radioresistant curves (Do = 2.2 Gy); the cells were more responsive when assayed by the Hamburger-Salmon method (Do = 1.5 Gy), and the soft agar and Courtenay-Mills assays gave the most radiosensitive curves (Do = 1.2 Gy). These results demonstrate that the PE of human tumor cell lines may be increased with no effect on radiation survival; radiation survival may be altered without changes in PE and neither may be altered by applying modifications and supplements to existing clonogenic assays.

  12. Transport in Stochastic Media

    International Nuclear Information System (INIS)

    Haran, O.; Shvarts, D.; Thieberger, R.

    1998-01-01

    Classical transport of neutral particles in a binary, scattering, stochastic media is discussed. It is assumed that the cross-sections of the constituent materials and their volume fractions are known. The inner structure of the media is stochastic, but there exist a statistical knowledge about the lump sizes, shapes and arrangement. The transmission through the composite media depends on the specific heterogeneous realization of the media. The current research focuses on the averaged transmission through an ensemble of realizations, frm which an effective cross-section for the media can be derived. The problem of one dimensional transport in stochastic media has been studied extensively [1]. In the one dimensional description of the problem, particles are transported along a line populated with alternating material segments of random lengths. The current work discusses transport in two-dimensional stochastic media. The phenomenon that is unique to the multi-dimensional description of the problem is obstacle bypassing. Obstacle bypassing tends to reduce the opacity of the media, thereby reducing its effective cross-section. The importance of this phenomenon depends on the manner in which the obstacles are arranged in the media. Results of transport simulations in multi-dimensional stochastic media are presented. Effective cross-sections derived from the simulations are compared against those obtained for the one-dimensional problem, and against those obtained from effective multi-dimensional models, which are partially based on a Markovian assumption

  13. Correlation between the genotoxicity endpoints measured by two different genotoxicity assays: comet assay and CBMN assay

    Directory of Open Access Journals (Sweden)

    Carina Ladeira

    2015-06-01

    The results concerning of positive findings by micronuclei and non significant ones by comet assay, are corroborated by Deng et al. (2005 study performed in workers occupationally exposed to methotrexate, also a cytostatic drug. According to Cavallo et al. (2009, the comet assay seems to be more suitable for the prompt evaluation of the genotoxic effects, for instance, of polycyclic aromatic hydrocarbons mixtures containing volatile substances, whereas the micronucleus test seems more appropriate to evaluate the effects of exposure to antineoplastic agents. However, there are studies that observed an increase in both the comet assay and the micronucleus test in nurses handling antineoplastic drugs, although statistical significance was only seen in the comet assay, quite the opposite of our results (Maluf & Erdtmann, 2000; Laffon et al. 2005.

  14. Media relations after the introduction of social media

    OpenAIRE

    Mesila, Helin

    2010-01-01

    In the light of the popularity of social media on one hand, and the contradictive relationships between journalists and public relations practitioners on the other hand, the thesis studies media relations after the introduction of social media. The study focuses on media relations in Estonian public relations scenery. The research answers to the questions: - What are media relations today? - What are the functions of social media and media relations in organizational communication? ...

  15. Media education and media enlightenment as attributes of information society

    Directory of Open Access Journals (Sweden)

    Лилия Борисовна Белоглазова

    2014-12-01

    Full Text Available The article deals with the problem of the functioning of media-education and media-enlightenment in modern society. Focuses on the impact of this socio-cultural phenomenon on consciousness of members of the Information Society. Are the main characteristics of media-education and media-education and media-enlightenment. Concludes that media-education and media-enlightenment forms unscientific and anti-scientific thinking and style speech.

  16. Bulk temperature measurement in thermally striped pipe flows

    International Nuclear Information System (INIS)

    Lemure, N.; Olvera, J.R.; Ruggles, A.E.

    1995-12-01

    The hot leg flows in some Pressurized Water Reactor (PWR) designs have a temperature distribution across the pipe cross-section. This condition is often referred to as a thermally striped flow. Here, the bulk temperature measurement of pipe flows with thermal striping is explored. An experiment is conducted to examine the feasibility of using temperature measurements on the external surface of the pipe to estimate the bulk temperature of the flow. Simple mixing models are used to characterize the development of the temperature profile in the flow. Simple averaging techniques and Backward Propagating Neural Net are used to predict bulk temperature from the external temperature measurements. Accurate bulk temperatures can be predicted. However, some temperature distributions in the flow effectively mask the bulk temperature from the wall and cause significant error in the bulk temperature predicted using this technique

  17. A CFT perspective on gravitational dressing and bulk locality

    Energy Technology Data Exchange (ETDEWEB)

    Lewkowycz, Aitor; Turiaci, Gustavo J. [Physics Department, Princeton University,Princeton, NJ 08544 (United States); Verlinde, Herman [Physics Department, Princeton University,Princeton, NJ 08544 (United States); Princeton Center for Theoretical Science, Princeton University,Princeton, NJ 08544 (United States)

    2017-01-02

    We revisit the construction of local bulk operators in AdS/CFT with special focus on gravitational dressing and its consequences for bulk locality. Specializing to 2+1-dimensions, we investigate these issues via the proposed identification between bulk operators and cross-cap boundary states. We obtain explicit expressions for correlation functions of bulk fields with boundary stress tensor insertions, and find that they are free of non-local branch cuts but do have non-local poles. We recover the HKLL recipe for restoring bulk locality for interacting fields as the outcome of a natural CFT crossing condition. We show that, in a suitable gauge, the cross-cap states solve the bulk wave equation for general background geometries, and satisfy a conformal Ward identity analogous to a soft graviton theorem. Virasoro symmetry, the large N conformal bootstrap and the uniformization theorem all play a key role in our derivations.

  18. Organizational Communication and Media

    DEFF Research Database (Denmark)

    Tække, Jesper

      The paper reflects an interest in the relation between organizational communication and media. It tries to answer the question, how we can observe the relationship between organizational communication and media. It is a work-in-progress which tries to combine organizational studies inspired...... of Niklas Luhmann (Tække & Paulsen 2008, Tække 2008a) with analysis of how organizations communicate in and about media. Using systems theory and form theory, it puts forward a theoretical framework and a strategy for analysing organisational communication in and about media. The medium aspect is inspired...... is a possible framework to draw the two disciplines together in, because it is a theory about the relation between the social and the media it is based on. First the paper sum up the Luhmann inspired theory about organizations, fleshing out how organizations are thought to communicate in and about media and how...

  19. Social media visibility

    DEFF Research Database (Denmark)

    Uldam, Julie

    2018-01-01

    of activists remains under-researched. This article examines BP’s surveillance of activists who criticise the company’s corporate social responsibility (CSR) programme as ‘greenwashing’. In this way, it goes beyond corporations’ uses of big data and instead explores how they monitor and discuss strategies......As activists move from alternative media platforms to commercial social media platforms, they face increasing challenges in protecting their online security and privacy. While government surveillance of activists is well-documented in scholarly research and the media, corporate surveillance...... for responding to the activities of individual activists in social media. It shows that while social media afford an unprecedented level of visibility for activists, it comes with the risk of being monitored by corporations. Theoretically, it draws on conceptions of visibility in social sciences and media...

  20. The Media Mixer

    DEFF Research Database (Denmark)

    Vestergaard, Vitus; Mortensen, Christian Hviid

    In recent years many museums have experimented with different approaches to involving users through digital media. We explore how remixing and content sharing can be used as a means for user participation. Remix culture is seen as a culture that allows and encourages the production of derivative...... works; works that are based on already existing works. This cultural practice thrives throughout the Internet, most notably on web2.0 sites like YouTube. The Media Museum has embraced the remix paradigm with the development of an interactive media experience centre called the Media Mixer. Here...... the museum users can produce, deconstruct, reconstruct and finally publish and share digital media content. The media content is created by the user in the museums physical environment, but it can be mixed with material from local or global archives. In that way the gap between the analogue and the digital...

  1. Abortion in the media.

    Science.gov (United States)

    Conti, Jennifer A; Cahill, Erica

    2017-12-01

    To review updates in how abortion care is depicted and analysed though various media outlets: news, television, film, and social media. A surge in recent media-related abortion research has recognized several notable and emerging themes: abortion in the news media is often inappropriately sourced and politically motivated; abortion portrayal in US film and television is frequently misrepresented; and social media has a new and significant role in abortion advocacy. The portrayal of abortion onscreen, in the news, and online through social media has a significant impact on cultural, personal, and political beliefs in the United States. This is an emerging field of research with wide spread potential impact across several arenas: medicine, policy, public health.

  2. Internal Social Media

    DEFF Research Database (Denmark)

    Madsen, Vibeke Thøis

    2018-01-01

    Internal social media is a web-based communication arena that provides all organizational members with a communication opportunity. The media has emerged in organizations since 2004, and is increasingly seen as a way of giving employees a voice in organizations which can benefit the organization...... in terms of knowledge sharing, collaboration, and employee participation and engagement. The first wave of studies of internal social media was primarily from an information-systems perspective and focused more on its adoption, its affordances, and the outcome of its introduction. The second wave...... of studies was more concerned with studying the dynamics of communication on internal social media, in order to understand coworkers as strategic communicators and how communication on internal social media can constitute the organization. With a successful introduction of internal social media, coworkers...

  3. New Media, New Citizens?

    DEFF Research Database (Denmark)

    Ohme, Jakob

    as for different age groups, the thesis shows that digital and especially social media use can be a strong driver of citizen participation. Besides looking at immediate mobilizing effects, the book sheds light on how digital media use may shape participation patterns through a long-term change in citizenship......The use of news media is regarded as a driver for citizens’ engagement with society and their political participation. But as news media use increasingly shifts to digital platforms, it is crucial to understand the interplay between a changing media environment and recent patterns of political...... participation. Against the background of citizens’ diverse possibilities for receiving political information and being politically active nowadays, the book focuses on the impact of digital media on political participation in Denmark. By examining this relationship in election- and non-election times as well...

  4. Bulk glass formation and crystallization in zirconium based bulk metallic glass forming alloys

    International Nuclear Information System (INIS)

    Savalia, R.T.; Neogy, S.; Dey, G.K.; Banerjee, S.

    2002-01-01

    The microstructures of Zr based metallic glasses produced in bulk form have been described in the as-cast condition and after crystallization. Various microscopic techniques have been used to characterize the microstructures. The microstructure in the as-cast condition was found to contain isolated crystals and crystalline aggregates embedded in the amorphous matrix. Quenched-in nuclei of crystalline phases were found to be present in fully amorphous regions. These glasses after crystallization gave rise to nanocrystalline solids. (author)

  5. 75 FR 34573 - Bulk Solid Hazardous Materials: Harmonization With the International Maritime Solid Bulk Cargoes...

    Science.gov (United States)

    2010-06-17

    ... reduced iron (DRI) as briquettes molded at a temperature of 650 [deg]C or higher that have a density of 5... temperature of 650 [deg]C or higher or had a density of 5.0 g/cm[sup3] or greater. In this proposed rule, we... bulk materials of Hazard Classes 4 through 9. c. One comment recommended that a DCM be required for...

  6. Orchestrating the Media Collage

    Science.gov (United States)

    Ohler, Jason

    2009-01-01

    Modern literacy has always meant being able to both read and write narrative in the media forms of the day, whatever they may be. Just being able to read is not sufficient. A new dimension of literacy is now in play--namely, the ability to adapt to new media forms and fit them into the overall media collage quickly and effectively. A strong case…

  7. Curing characteristics of flowable and sculptable bulk-fill composites

    OpenAIRE

    Miletic, Vesna; Pongpruenska, Pong; De Munck, Jan; Brooks, Neil R; Van Meerbeek, Bart

    2016-01-01

    OBJECTIVES: The aim of this study was to determine and correlate the degree of conversion (DC) with Vickers hardness (VH) and translucency parameter (TP) with the depth of cure (DoC) of five bulk-fill composites. MATERIALS AND METHODS: Six specimens per group, consisting of Tetric EvoCeram Bulk Fill ("TEC Bulk," Ivoclar Vivadent), SonicFill (Kerr), SDR Smart Dentin Replacement ("SDR," Dentsply), Xenius base ("Xenius," StickTech; commercialized as EverX Posterior, GC), Filtek Bul...

  8. Theory of bulk-surface coupling in topological insulator films

    Science.gov (United States)

    Saha, Kush; Garate, Ion

    2014-12-01

    We present a quantitative microscopic theory of the disorder- and phonon-induced coupling between surface and bulk states in doped topological insulator films. We find a simple mathematical structure for the surface-to-bulk scattering matrix elements and confirm the importance of bulk-surface coupling in transport and photoemission experiments, assessing its dependence on temperature, carrier density, film thickness, and particle-hole asymmetry.

  9. Localization of bulk form fields on dilatonic domain walls

    International Nuclear Information System (INIS)

    Youm, Donam

    2001-06-01

    We study the localization properties of bulk form potentials on dilatonic domain walls. We find that bulk form potentials of any ranks can be localized as form potentials of the same ranks or one lower ranks, for any values of the dilaton coupling parameter. For large enough values of the dilaton coupling parameter, bulk form potentials of any ranks can be localized as form potentials of both the same ranks and one lower ranks. (author)

  10. AFLP marker linked to water-stress-tolerant bulks in barley (Hordeum vulgare L.

    Directory of Open Access Journals (Sweden)

    A. Altinkut

    2003-01-01

    Full Text Available The amplified fragment length polymorphism (AFLP assay is an efficient method for the identification of molecular markers, useful in the improvement of numerous crop species. Bulked Segregant Analysis (BSA was used to identify AFLP markers associated with water-stress tolerance in barley, as this would permit rapid selection of water-stress tolerant genotypes in breeding programs. AFLP markers linked to water-stress tolerance was identified in two DNA pools (tolerant and sensitive, which were established using selected F2 individuals resulting from a cross between water-stress-tolerant and sensitive barley parental genotypes, based on their paraquat (PQ tolerance, leaf size, and relative water content (RWC. All these three traits were previously shown to be associated with water-stress tolerance in segregating F2 progeny of the barley cross used in a previous study. AFLP analysis was then performed on these DNA pools, using 40 primer pairs to detect AFLP fragments that are present/absent, respectively, in the two pools and their parental lines. One separate AFLP fragment, which was present in the tolerant parent and in the tolerant bulk, but absent in the sensitive parent and in the sensitive bulk, was identified. Polymorphism of the AFLP marker was tested among tolerant and sensitive F2 individuals. The presence of this marker that is associated with water-stress tolerance will greatly enhance selection for paraquat and water-stress tolerant genotypes in future breeding programs.

  11. Quantitative monitoring of activity-dependent bulk endocytosis of synaptic vesicle membrane by fluorescent dextran imaging

    Science.gov (United States)

    Clayton, Emma Louise; Cousin, Michael Alan

    2012-01-01

    Activity-dependent bulk endocytosis (ADBE) is the dominant synaptic vesicle (SV) retrieval mode in central nerve terminals during periods of intense neuronal activity. Despite this fact there are very few real time assays that report the activity of this critical SV retrieval mode. In this paper we report a simple and quantitative assay of ADBE using uptake of large flourescent dextrans as fluid phase markers. We show that almost all dextran uptake occurs in nerve terminals, using co-localisation with the fluorescent probe FM1-43. We also demonstrate that accumulated dextran cannot be unloaded by neuronal stimulation, indicating its specific loading into bulk endosomes and not SVs. Quantification of dextran uptake was achieved by using thresholding analysis to count the number of loaded nerve terminals, since monitoring the average fluorescence intensity of these nerve terminals did not accurately report the extent of ADBE. Using this analysis we showed that dextran uptake occurs very soon after stimulation and that it does not persist when stimulation terminates. Thus we have devised a simple and quantitative method to monitor ADBE in living neurones, which will be ideal for real time screening of small molecule inhibitors of this key SV retrieval mode. PMID:19766140

  12. The digital media handbook

    CERN Document Server

    Dewdney, Andrew

    2013-01-01

    The new edition of The Digital Media Handbook presents an essential guide to the historical and theoretical development of digital media, emphasising cultural continuity alongside technological change, and highlighting the emergence of new forms of communication in contemporary networked culture.Andrew Dewdney and Peter Ride present detailed critical commentary and descriptive historical accounts, as well as a series of interviews from a range of digital media practitioners, including producers, developers, curators and artists.The Digital Media Handbook highlights key concerns of today's prac

  13. Media Monopoly in Brazil.

    Science.gov (United States)

    Amaral, Roberto; Guimaraes, Cesar

    1994-01-01

    Documents the process of broadcasting media development in Brazil, the failure of new technologies to produce democratization, and the barriers to democratization erected by monopolization and "metastasis." (SR)

  14. Overview: new media.

    Science.gov (United States)

    O'Keeffe, Gwenn Schurgin

    2012-06-01

    Pediatricians care for children's growth and development from the time they are born until they become adults. In addition, pediatricians must be vigilant for external influences. Technology influences children of all ages. Seventy-five percent of teenagers own cell phones, with 25% using them for social media. Technology can lead to an increase in skills and social benefits but there is also the potential for harm such as sexting, cyberbullying, privacy issues, and Internet addiction, all of which can affect health. Pediatricians must become well versed in the new media to provide media-oriented anticipatory guidance and advice on media-related issues. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Antennas in inhomogeneous media

    CERN Document Server

    Galejs, Janis; Fock, V A; Wait, J R

    2013-01-01

    Antennas in Inhomogeneous Media details the methods of analyzing antennas in such inhomogeneous media. The title covers the complex geometrical configurations along with its variational formulations. The coverage of the text includes various conditions the antennas are subjected to, such as antennas in the interface between two media; antennas in compressible isotropic plasma; and linear antennas in a magnetoionic medium. The selection also covers insulated loops in lossy media; slot antennas with a stratified dielectric or isotropic plasma layers; and cavity-backed slot antennas. The book wil

  16. Media multitasking in adolescence.

    Science.gov (United States)

    Cain, Matthew S; Leonard, Julia A; Gabrieli, John D E; Finn, Amy S

    2016-12-01

    Media use has been on the rise in adolescents overall, and in particular, the amount of media multitasking-multiple media consumed simultaneously, such as having a text message conversation while watching TV-has been increasing. In adults, heavy media multitasking has been linked with poorer performance on a number of laboratory measures of cognition, but no relationship has yet been established between media-multitasking behavior and real-world outcomes. Examining individual differences across a group of adolescents, we found that more frequent media multitasking in daily life was associated with poorer performance on statewide standardized achievement tests of math and English in the classroom, poorer performance on behavioral measures of executive function (working memory capacity) in the laboratory, and traits of greater impulsivity and lesser growth mindset. Greater media multitasking had a relatively circumscribed set of associations, and was not related to behavioral measures of cognitive processing speed, implicit learning, or manual dexterity, or to traits of grit and conscientiousness. Thus, individual differences in adolescent media multitasking were related to specific differences in executive function and in performance on real-world academic achievement measures: More media multitasking was associated with poorer executive function ability, worse academic achievement, and a reduced growth mindset.

  17. Open Media Science

    DEFF Research Database (Denmark)

    Møller Moltke Martiny, Kristian; Pedersen, David Budtz; Hansted, Allan Alfred Birkegaard

    2016-01-01

    In this article, we present three challenges to the emerging Open Science (OS) movement: the challenge of communication, collaboration and cultivation of scientific research. We argue that to address these challenges OS needs to include other forms of data than what can be captured in a text...... and extend into a fully-fledged Open Media movement engaging with new media and non-traditional formats of science communication. We discuss two cases where experiments with open media have driven new collaborations between scientists and documentarists. We use the cases to illustrate different advantages...... of using open media to face the challenges of OS....

  18. Barcoded microchips for biomolecular assays.

    Science.gov (United States)

    Zhang, Yi; Sun, Jiashu; Zou, Yu; Chen, Wenwen; Zhang, Wei; Xi, Jianzhong Jeff; Jiang, Xingyu

    2015-01-20

    Multiplexed assay of analytes is of great importance for clinical diagnostics and other analytical applications. Barcode-based bioassays with the ability to encode and decode may realize this goal in a straightforward and consistent manner. We present here a microfluidic barcoded chip containing several sets of microchannels with different widths, imitating the commonly used barcode. A single barcoded microchip can carry out tens of individual protein/nucleic acid assays (encode) and immediately yield all assay results by a portable barcode reader or a smartphone (decode). The applicability of a barcoded microchip is demonstrated by human immunodeficiency virus (HIV) immunoassays for simultaneous detection of three targets (anti-gp41 antibody, anti-gp120 antibody, and anti-gp36 antibody) from six human serum samples. We can also determine seven pathogen-specific oligonucleotides by a single chip containing both positive and negative controls.

  19. Radiological safety and GMP in the bulk batch manufacturing, formulation and dispensing of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Thulasidhasan, A.; Tiwary, Bikash; Kumar, Uma Sheri; Kale, Pooja; Tiwary, Richa; Gaurav, Ananad; Shah, B.K.; Topale, P.D.; Prabhakar, G.; Sachdev, S.S.

    2010-01-01

    to ensure safety to the occupational workers and to the environment. Radiological safety both at personnel and environmental level is ensured at BRIT facility, by strictly adhering to the following standard operation protocols based on the ALARA principle. (i) Before starting the production, the facility (Production Plant/Glove Box/Fume hood), 'Safety protocol document' is prepared, checked and certified by Health Physicist and all safety documents and records are completed. This is to ensure proper negative pressure, air flow, integrity of the Neoprene gloves, Radiation field check and facility equipment to be used, namely, trolley, dry heat bath, pumps, pantographs, dispensing equipment, vacuum lines etc. are working properly. For assuring pharmaceutical quality all good manufacturing practice (GMP) guidelines are followed. All raw materials, carriers, buffers and glassware used are sterile and pyrogen free. The facility meant for processing is made to comply with the environmental control test. This is ensured by spraying and mopping the facility with ethyl alcohol, exposing the area with UV lights and testing the suitability with agar media plate test. For injectable products namely 131 I MIBG injection, 153 Sm-EDTMP injection and 32 P- Sodium orthophosphate injection, GMP compliance requirements are stringent. (ii) Salient steps of production SOP include, transfer of bulk raw material radioisotope, required reagents, chemicals and sterile glassware, in the production plant,. The product is formulated, sterilized and dispensed in required doses. This is with strict adherence to the Radiopharmaceuticals Committee (RPC) approved production manuals. (iii) All the products are then sampled and tested according to Radiopharmaceuticals Committee (RPC) approved production monographs by Radiopharmaceutical Quality Control Program of BRIT. Continuous monitoring is an essential part of any radiation safety program and radiation surveillance, is provided to all radioactive

  20. Photoelectron spectroscopy bulk and surface electronic structures

    CERN Document Server

    Suga, Shigemasa

    2014-01-01

    Photoelectron spectroscopy is now becoming more and more required to investigate electronic structures of various solid materials in the bulk, on surfaces as well as at buried interfaces. The energy resolution was much improved in the last decade down to 1 meV in the low photon energy region. Now this technique is available from a few eV up to 10 keV by use of lasers, electron cyclotron resonance lamps in addition to synchrotron radiation and X-ray tubes. High resolution angle resolved photoelectron spectroscopy (ARPES) is now widely applied to band mapping of materials. It attracts a wide attention from both fundamental science and material engineering. Studies of the dynamics of excited states are feasible by time of flight spectroscopy with fully utilizing the pulse structures of synchrotron radiation as well as lasers including the free electron lasers (FEL). Spin resolved studies also made dramatic progress by using higher efficiency spin detectors and two dimensional spin detectors. Polarization depend...

  1. Fault current limiter using bulk oxides superconductors

    International Nuclear Information System (INIS)

    Belmont, O.; Ferracci, P.; Porcar, L.; Barbut, J.M.; Tixador, P.; Noudem, J.G.; Bourgault, D.; Tournier, R.

    1998-01-01

    We study the limitation possibilities of bulk Bi high T c materials. For this we test these materials with AC or DC currents above their critical currents. We study particularly the evolution of the voltage with time or with current. The material, the value of the current and the time duration play important parts. For sintered Bi samples the voltage depends only on the current even for values much larger than the critical current. With textured samples the V(I) curves shows an hysteretic behaviour due to a warming up. The textured materials are more interesting than sintered ones in terms of required volume for the current limitation. In both cases the superconductors are in a dissipative state but not in the normal state. This state is nevertheless reached if the dissipated energy inside the sample is sufficient. We have tried to apply a magnetic field on the samples in order to trigger a more effective limitation. The voltage increases but with a limited effect for currents much higher (3-4 times) than the critical zero field current. We think that the dissipative state is due mainly to the grain boundaries which become resistive above the critical current. (orig.)

  2. Thermodynamic properties of bulk and confined water

    Energy Technology Data Exchange (ETDEWEB)

    Mallamace, Francesco, E-mail: francesco.mallamace@unime.it [Dipartimento di Fisica e Scienza della Terra Università di Messina and CNISM, I-98168 Messina (Italy); Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215 (United States); Corsaro, Carmelo [Dipartimento di Fisica e Scienza della Terra Università di Messina and CNISM, I-98168 Messina (Italy); Mallamace, Domenico [Dipartimento di Scienze dell' Ambiente, della Sicurezza, del Territorio, degli Alimenti e della Salute, Università di Messina, I-98166 Messina (Italy); Vasi, Sebastiano; Vasi, Cirino [IPCF-CNR, I-98166 Messina (Italy); Stanley, H. Eugene [Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215 (United States)

    2014-11-14

    The thermodynamic response functions of water display anomalous behaviors. We study these anomalous behaviors in bulk and confined water. We use nuclear magnetic resonance (NMR) to examine the configurational specific heat and the transport parameters in both the thermal stable and the metastable supercooled phases. The data we obtain suggest that there is a behavior common to both phases: that the dynamics of water exhibit two singular temperatures belonging to the supercooled and the stable phase, respectively. One is the dynamic fragile-to-strong crossover temperature (T{sub L} ≃ 225 K). The second, T{sup *} ∼ 315 ± 5 K, is a special locus of the isothermal compressibility K{sub T}(T, P) and the thermal expansion coefficient α{sub P}(T, P) in the P–T plane. In the case of water confined inside a protein, we observe that these two temperatures mark, respectively, the onset of protein flexibility from its low temperature glass state (T{sub L}) and the onset of the unfolding process (T{sup *})

  3. Studies of bulk heterojunction solar cells

    Science.gov (United States)

    Cossel, Raquel; McIntyre, Max; Tzolov, Marian

    We are studying bulk heterojunction solar cells that were fabricated using a mixture of PCPDTBT and PCBM­C60. The impedance data of the cells in dark responded like a simple RC circuit. The value of the dielectric constant derived from these results is consistent with the values reported in the literature for these materials. We are showing that the parallel resistance in the equivalent circuit of linear lump elements can be interpreted using the DC current­voltage measurements. The impedance spectra under light illumination indicated the existence of additional polarization. This extra feature can be described by a model that includes a series RC circuit in parallel with the equivalent circuit for a device in dark. The physical interpretation of the additional polarization is based on photo­generated charges getting trapped in wells, which have a characteristic relaxation time corresponding to the observed break frequency in the impedance spectra. We have studied the influence of the anode and cathode interface on this phenomena, either by using different interface materials, or by depositing the metal electrode while the substate is heated.

  4. Bulk water freezing dynamics on superhydrophobic surfaces

    Science.gov (United States)

    Chavan, S.; Carpenter, J.; Nallapaneni, M.; Chen, J. Y.; Miljkovic, N.

    2017-01-01

    In this study, we elucidate the mechanisms governing the heat-transfer mediated, non-thermodynamic limited, freezing delay on non-wetting surfaces for a variety of characteristic length scales, Lc (volume/surface area, 3 mm commercial superhydrophobic spray coatings, showing a monotonic increase in freezing time with coating thickness. The added thermal resistance of thicker coatings was much larger than that of the nanoscale superhydrophobic features, which reduced the droplet heat transfer and increased the total freezing time. Transient finite element method heat transfer simulations of the water slab freezing process were performed to calculate the overall heat transfer coefficient at the substrate-water/ice interface during freezing, and shown to be in the range of 1-2.5 kW/m2K for these experiments. The results shown here suggest that in order to exploit the heat-transfer mediated freezing delay, thicker superhydrophobic coatings must be deposited on the surface, where the coating resistance is comparable to the bulk water/ice conduction resistance.

  5. Calcium Isotopic Composition of Bulk Silicate Earth

    Science.gov (United States)

    Kang, J.; Ionov, D. A.; Liu, F.; Zhang, C.; Zhang, Z.; Huang, F.

    2016-12-01

    Ca isotopes are used to study the accretion history of the Earth and terrestrial planets, but, Ca isotopic composition of the Bulk Silicate Earth (BSE) remains poorly constrained [1]. To better understand the Ca isotopic composition of BSE, we analyzed 22 well studied peridotite xenoliths from Tariat (Mongolia), Vitim (southern Siberia) and Udachnaya (Siberian Craton). These samples include both fertile and highly depleted garnet and spinel peridotites that show no or only minor post-melting metasomatism or alteration. Ca isotope measurements were done on a Triton-TIMS using double spike method at the Guangzhou Institute of Geochemistry, CAS. The data are reported as δ44/40Ca (relative to NIST SRM 915a). Results for geostandards are consistent with those from other laboratories. 2 standard deviations of SRM 915a analyses are 0.13‰ (n=48). δ44/40Ca of both and fertile and refractory peridotites range from 0.79 to 1.07‰ producing an average of 0.93±0.12‰ (2SD). This value defines the Ca isotopic composition of the BSE, which is consistent with the average δ44/40Ca of oceanic basalts ( 0.90‰)[2,3]. [1] Huang et al (2010) EPSL 292; [2] Valdes et al (2014) EPSL 394; [3]DePaolo (2004) RMG 55.

  6. Particle size distributions, size concentration relationships, and adherence to hands of selected geologic media derived from mining, smelting, and quarrying activities

    Energy Technology Data Exchange (ETDEWEB)

    Bergstrom, Carolyn; Shirai, Jeffry; Kissel, John, E-mail: jkissel@uw.edu

    2011-09-15

    Hand-to-mouth activity, especially in children, is a potentially significant pathway of exposure to soil contaminants. Hand-mouthing behavior is of particular concern in areas impacted by mining, smelting, and quarrying activities as these activities may lead to elevated levels of heavy metals in soil. In order to estimate potential exposures to contaminated geologic media attributable to hand-to-mouth contact, it is useful to characterize adherence of those media to skin, as contaminant concentrations in adhered media may differ greatly from unfractionated, whole media concentrations. Such an investigation has been undertaken to aid estimation of exposures to arsenic, cadmium, lead, and zinc in nine different geologic media collected in the Pacific Northwest region of the United States. After establishing the particle size distribution of each medium (fractions < 63 {mu}m, 63-150 {mu}m, 150-250 {mu}m, and 250 {mu}m-2 mm were determined) and target elemental concentrations within each particle size fraction, an active handling protocol involving six volunteers was conducted. Wet media always adhered to a greater extent than dry media and adhered media generally had higher elemental concentrations than bulk media. Regression analyses suggest smaller particle fractions may have higher elemental concentrations. Results of application of a maximum likelihood estimation technique generally indicate that handling of dry media leads to preferential adherence of smaller particle sizes, while handling of wet media does not. Because adhered material can differ greatly in particle size distribution from that found in bulk material, use of bulk concentrations in exposure calculations may lead to poor estimation of actual exposures. Since lead has historically been a metal of particular concern, EPA's Integrated Exposure Uptake Biokinetic (IEUBK) Model was used to examine the potential consequences of evaluating ingestion of the selected media assuming concentrations in

  7. Alpha chymotrypsin coated clusters of Fe3O4 nanoparticles for biocatalysis in low water media

    Directory of Open Access Journals (Sweden)

    Mukherjee Joyeeta

    2012-11-01

    Full Text Available Abstract Background Enzymes in low water containing non aqueous media are useful for organic synthesis. For example, hydrolases in such media can be used for synthetic purposes. Initial work in this area was carried out with lyophilized powders of enzymes. These were found to have poor activity. Drying (removing bulk water by precipitation turned out to be a better approach. As enzymes in such media are heterogeneous catalysts, spreading these precipitates over a large surface gave even better results. In this context, nanoparticles with their better surface to volume ratio provide obvious advantage. Magnetic nanoparticles have an added advantage of easy separation after the reaction. Keeping this in view, alpha chymotrypsin solution in water was precipitated over a stirred population of Fe3O4 nanoparticles in n-propanol. This led to alpha chymotrypsin activity coated over clusters of Fe3O4 nanoparticles. These preparations were found to have quite high transesterification activity in low water containing n-octane. Results Precipitation of alpha chymotrypsin over a stirred suspension of Fe3O4 nanoparticles (3.6 nm diameter led to the formation of enzyme coated clusters of nanoparticles (ECCNs. These clusters were also magnetic and their hydrodynamic diameter ranged from 1.2- 2.6 microns (as measured by dynamic light scattering. Transmission electron microscopy (TEM, showed that these clusters had highly irregular shapes. Transesterification assay of various clusters in anhydrous n-octane led to optimization of concentration of nanoparticles in suspension during precipitation. Optimized design of enzyme coated magnetic clusters of nanoparticles (ECCN 3 showed the highest initial rate of 465 nmol min-1 mg-1protein which was about 9 times higher as compared to the simple precipitates with an initial rate of 52 nmol min-1 mg-1 protein. Circular Dichroism (CD(with a spinning cell accessory showed that secondary structure content of the alpha

  8. Making Media Studies

    Directory of Open Access Journals (Sweden)

    David Gauntlett

    2015-12-01

    Full Text Available This podcast is a recording of a research seminar that took place on December 3, 2015, at the University of Westminster's Communication and Media Research Institute (CAMRI. In this contribution, David Gauntlett discusses his new book, Making Media Studies, and other new work. In Making Media Studies (Peter Lang, 2015, Gauntlett proposes a vision of media studies based around doing and making – not about the acquisition of skills, as such, but an experience of building knowledge and understanding through creative hands-on engagement with all kinds of media. Gauntlett suggests that media studies scholars have failed to recognise the significance of everyday creativity – the vital drive of people to make, exchange, and learn together, supported by online networks. He argues that we should think about media in terms of conversations, inspirations, and making things happen. Media studies can be about genuine social change, he suggests, if we recognise the significance of everyday creativity, work to transform our tools, and learn to use them wisely. David Gauntlett is a Professor in the School of Media, Arts and Design at the University of Westminster, where he is also the School's Co-Director of Research. He is the author of several books, including: Creative Explorations (2007, Media, Gender and Identity: An Introduction (2nd edition 2008, Making is Connecting (2011, and Making Media Studies (2015. He has made a number of popular online resources, videos and playthings, and has pioneered creative research and workshop methods. He is external examiner for Information Experience Design at the Royal College of Art, London.

  9. Educational Potential of New Media

    Directory of Open Access Journals (Sweden)

    Maria Yu. Kazak

    2017-11-01

    Full Text Available Digitalization of the mass media, which has radically changed the information environment, creates new opportunities for self-education and upgrowth of the audience. The paper defines the communicative and cultural status of new media, characterizes the socio-cultural and technological aspects of their dynamics; substantiates the necessity of elaborating mechanisms for systematization of heterogeneous information flows and elaborating criteria for their evaluation in the era of globalization of the media sphere, what implies a qualitatively different level of media competence of the audience, provided with such factors as media education, media coverage, media criticism. The definition of concepts "media competence", "media enlightenment", "media education", "media criticism" is given and their functional areas are delineated. Social networks are considered as an important tool for media enlightenment which provides significant opportunities for promoting cultural achievements in the new media environment.

  10. Media Anthropology: A Theoretical Framework

    Science.gov (United States)

    Eiselein, E. B.; Topper, Martin

    1976-01-01

    Media anthropology, a diverse field, has involved nearly all the major subdisciplines of anthropology and most of the major media in five different areas of interaction: the study of media, reaching the public, gathering data, teaching with media, and applied media anthropology. (NQ)

  11. Correlating intravenous radiographic contrast media reactions with the allergic profile

    International Nuclear Information System (INIS)

    Chua-Lim, A.; Enright, T.; Duda, E.; Lim, D.T.

    1987-01-01

    To determine the relevance of allergy as a predisposing factor in reactions to radiographic contrast media, the authors investigated the incidence of allergy among 100 randomly selected patients undergoing intravenous excretory urography and CT. The study population consisted of 50 reactors and 50 nonreactos to radiographic contrast media. All 100 subjects completed an allergy history, percutaneous allergy tests, and an in vitro specific IgE assay to common allergens. Thirty-four of 50 reactors had a positive allergy history, in contrast to 15 of 50 nonreactors (P < .001). Twenty-seven reactors had positive skin tests, in contrast to 12 of 50 nonreactors (P < .005). In vitro IgE assay results are pending. The results indicate that patients with positive histories or positive skin tests or both are at an increased risk for reactions to radiographic contrast media

  12. Chromosome aberration assays in Allium

    Energy Technology Data Exchange (ETDEWEB)

    Grant, W.F.

    1982-01-01

    The common onion (Allium cepa) is an excellent plant for the assay of chromosome aberrations after chemical treatment. Other species of Allium (A. cepa var. proliferum, A. carinatum, A. fistulosum and A. sativum) have also been used but to a much lesser extent. Protocols have been given for using root tips from either bulbs or seeds of Allium cepa to study the cytological end-points, such as chromosome breaks and exchanges, which follow the testing of chemicals in somatic cells. It is considered that both mitotic and meiotic end-points should be used to a greater extent in assaying the cytogenetic effects of a chemical. From a literature survey, 148 chemicals are tabulated that have been assayed in 164 Allium tests for their clastogenic effect. Of the 164 assays which have been carried out, 75 are reported as giving a positive reaction, 49 positive and with a dose response, 1 positive and temperature-related, 9 borderline positive, and 30 negative; 76% of the chemicals gave a definite positive response. It is proposed that the Allium test be included among those tests routinely used for assessing chromosomal damage induced by chemicals.

  13. Japanese Media in English.

    Science.gov (United States)

    Tanaka, Sachiko Oda

    1995-01-01

    Describes the use of English in the media in Japan, focusing on the role and history of English-language newspapers, radio, and television programs, as well as the proliferation of English-language films shown in Japanese cinemas. Discusses the implications of English in the Japanese media. (20 references) (MDM)

  14. Advertising Pressures on Media.

    Science.gov (United States)

    Hammitt, Harry

    The majority of the media in the United States is funded through revenues derived from the sale of advertising space. The problem that arises from this situation is fundamentally an economic one: if advertisers are paying the bills for the media, how much control over content should they have? This report offers a review of instances in which…

  15. Corporeal-Locomotive Media

    DEFF Research Database (Denmark)

    Nørgård, Rikke Toft

    and experiences such as reading or listening to a story and watching a movie or theatre play and other traditional or new media forms. These circumstances make the article question whether digital games can be understood as (new) media form at all and, thus, it points towards a possible new vocabulary...... for and comprehension of digital games, gameplay and gameplayers....

  16. A Religious Media Revolution?

    DEFF Research Database (Denmark)

    Skovgaard-Petersen, Jakob

    2016-01-01

    This article is a preliminary survey of the media usage of Sunni religious actors during the Syrian conflict. It traces the adoption of new media by religious actors, and analyses the kind of authority these actors have sought to embody, whether regime supporting, oppositional or jihadist...

  17. Loneliness and Media Gratifications.

    Science.gov (United States)

    Canary, Daniel J.; Spitzberg, Brian H.

    1993-01-01

    Assesses the nature of the relationship between experienced loneliness and media gratifications. Finds that chronically lonely college students rely less on media for escape than do others and that they reported the least motivation for watching their favorite soap opera. (SR)

  18. Media Entertainment and emotions

    DEFF Research Database (Denmark)

    Tan, Ed S.

    2017-01-01

    The chapter presents a psychological framework for entertainment experiences. It reviews types of emotion and their associations with media entertainment contents, explaining the role of genre.......The chapter presents a psychological framework for entertainment experiences. It reviews types of emotion and their associations with media entertainment contents, explaining the role of genre....

  19. Men, Myth, and Media.

    Science.gov (United States)

    Thoman, Elizabeth, Ed.; Silver, Rosalind, Ed.

    1989-01-01

    This issue on gender and the media contains the following (1) "Home, Home on the Remote"; (2) "Dads Through the Decades" (Mark Crispin Miller); (3) "The New Man: That's Entertainment!" (John Lehrer); (4) "Singing Men's Songs" (Kerry Skorlich); (5) "Media Myths and Men's Work" (Ian Harris); (6) "Why Are There No Asian Male Anchors?" (Ben…

  20. Austria: Media Dependence.

    Science.gov (United States)

    Signitzer, Benno

    1978-01-01

    Describes the Austrian broadcast industry which is dominated by foreign influences. Suggests the restoration of autonomy of Austria's media through a system of promotion of and subsidies to Austrian media efforts, as well as a decentralization of foreign influence to increase the quality and competitiveness of domestic production. (JMF)

  1. Mapping Media and Meaning

    DEFF Research Database (Denmark)

    Chamberlain, Alan; Bødker, Mads; Papangelis, Konstantinos

    2017-01-01

    places and intangible personal content can be used to develop meaningful experiences. The paper explores the use of autoethnography as a method for soundscape design in the fields of personal heritage and locative media. Specifically, we explore possible connections between digital media, space...

  2. Understanding social media logic

    NARCIS (Netherlands)

    van Dijck, J.; Poell, T.

    2013-01-01

    Over the past decade, social media platforms have penetrated deeply into the mech­anics of everyday life, affecting people's informal interactions, as well as institutional structures and professional routines. Far from being neutral platforms for everyone, social media have changed the conditions

  3. Literacy, Learning, and Media.

    Science.gov (United States)

    Adams, Dennis; Hamm, Mary

    2000-01-01

    Considers the expanding definition of literacy from traditional reading and writing skills to include technological, visual, information, and networking literacy. Discusses the impact of media on social interactions and intellectual development; linking technology to educational goals; influences of new media symbol systems on communication;…

  4. Introduction to Media.

    Science.gov (United States)

    Riler, Robert

    Designed for senior high school students, this one semester course focuses on four aspects of modern media: television, film, radio, and advertising. Each topic is worked into a weekly lesson plan format that stresses the active involvement of students in the learning process. The course outline contains lists of objectives and media materials…

  5. Work in the Media

    NARCIS (Netherlands)

    Deuze, M.

    2014-01-01

    As media have become dominant players in society’s affairs and, as an industry, represent a powerful economic and symbolic force, it is disheartening to see that work across the creative industries is becoming increasingly precarious. At the same time, media practitioners address this precarity in a

  6. Corporate Media Governance

    NARCIS (Netherlands)

    Kempen, Petrus Cornelis

    2011-01-01

    The media can make or break a reputation. This being said, it seems to be essential for companies, governments and institutions to pay specific attention to corporate media management in their daily operations. However, this thesis shows that they often neglect to pay adequate attention to corporate

  7. Building Social Media Connections

    Science.gov (United States)

    Ferriter, William N.; Ramsden, Jason T.; Sheninger, Eric C.

    2012-01-01

    Incorporating social media tools into your professional practices does not have to be intimidating as long as you are willing to tackle five action steps. It is far easier to articulate the strengths--and to imagine the possibilities--of social media spaces as tools for communication and professional development when you are actively using those…

  8. Bulk Vitrification Castable Refractory Block Protection Study

    Energy Technology Data Exchange (ETDEWEB)

    Hrma, Pavel R.; Bagaasen, Larry M.; Beck, Andrew E.; Brouns, Thomas M.; Caldwell, Dustin D.; Elliott, Michael L.; Matyas, Josef; Minister, Kevin BC; Schweiger, Michael J.; Strachan, Denis M.; Tinsley, Bronnie P.; Hollenberg, Glenn W.

    2005-05-01

    Bulk vitrification (BV) was selected for a pilot-scale test and demonstration facility for supplemental treatment to accelerate the cleanup of low-activity waste (LAW) at the Hanford U.S. DOE Site. During engineering-scale (ES) tests, a small fraction of radioactive Tc (and Re, its nonradioactive surrogate) were transferred out of the LAW glass feed and molten LAW glass, and deposited on the surface and within the pores of the castable refractory block (CRB). Laboratory experiments were undertaken to understand the mechanisms of the transport Tc/Re into the CRB during vitrification and to evaluate various means of CRB protection against the deposition of leachable Tc/Re. The tests used Re as a chemical surrogate for Tc. The tests with the baseline CRB showed that the molten LAW penetrates into CRB pores before it converts to glass, leaving deposits of sulfates and chlorides when the nitrate components decompose. Na2O from the LAW reacts with the CRB to create a durable glass phase that may contain Tc/Re. Limited data from a single CRB sample taken from an ES experiment indicate that, while a fraction of Tc/Re is present in the CRB in a readily leachable form, most of the Tc/Re deposited in the refractory is retained in the form of a durable glass phase. In addition, the molten salts from the LAW, mainly sulfates, chlorides, and nitrates, begin to evaporate from BV feeds at temperatures below 800 C and condense on solid surfaces at temperatures below 530 C. Three approaches aimed at reducing or preventing the deposition of soluble Tc/Re within the CRB were proposed: metal lining, sealing the CRB surface with a glaze, and lining the CRB with ceramic tiles. Metal liners were deemed unsuitable because evaluations showed that they can cause unacceptable distortions of the electric field in the BV system. Sodium silicate and a low-alkali borosilicate glaze were selected for testing. The glazes slowed down molten salt condensate penetration, but did little to reduce the

  9. Social Media Data in the Academic Environment: Crimson Hexagon in the Library

    OpenAIRE

    Tulley, Stephanie; Dennis, Tim

    2016-01-01

    Social media data is a high-profile resource across academic disciplines, in areas as diverse as understanding voter behavior, tracking social communication networks, and identifying sources and effects of pollution on human health. While manual data collection and review from public social media sites can provide some insight into the content of these sources, bulk access to data is preferred for more complex and deeper analysis into the content. A certain amount of data can be accessed dire...

  10. Xerophilic mycopopulations of teas in bulk

    Directory of Open Access Journals (Sweden)

    Škrinjar Marija M.

    2011-01-01

    Full Text Available d.o.o., Novi Sad AU Krunić Vesna J. AF EKOLd.o.o., Novi Sad KW teas % mould contamination % thermal treatment KR nema Other the water, tea is the most popular beverage in the world today. They are used for ages, in the beginning as refreshing drinks, and later more for their healing properties. Teas have been demonstrated to show antioxidative, anti-carcinogenic, and anti-microbial properties. Considering that the teas, during the production, are not treated with any temperature, there is high risk for contamination with different type of microorganisms, especially with moulds. Moulds are ubiquitously distributed in nature and their spores can be found in the atmosphere even at high altitudes and under favorable conditions of temperature and humidity, moulds grow on many commodities including cereals, oil seeds, nuts, herbs and spices. Most of them are potential producers of mycotoxins which present a real hazard to human health. The aim of this work was to investigate total mould count and to identify moulds isolated from teas in bulk, than from teas treated with hot, sterile, distilled water and from the tea filtrates. Tested teas were peppermint, sage, yarrow, black tea, bearberry, lemon balm, mixture of teas from Zlatibor. In teas in balk was observed high contamination with different kinds of moulds (1.84-4.55 cfu/g, such as Aspergillus awamori, A. lovaniensis, A niger, A. phoenicus, A. repens, A. restrictus, A. sydowii, A. versicolor, Eurotium amstelodami, E. chevalieri, E. herbariorum, Penicillium chrysogenum, and Scopulariopsis brevicaulis. The most frequent were species from Aspergillus and Eurotium genera. Thermal treatment with hot, sterile, distilled water reduced the number of fungal colonies. Aspergillus awamori was the most resistant and appeared in six samples of filtrates of tea, Aspergillus niger in one sample and Penicillium chrysogenum in one sample.

  11. High trapped fields in bulk YBCO superconductors

    Science.gov (United States)

    Fuchs, Günter; Gruss, Stefan; Krabbes, Gernot; Schätzle, Peter; Verges, Peter; Müller, Karl-Hartmut; Fink, Jörg; Schultz, Ludwig

    The trapped field properties of bulk melt-textured YBCO material were investigated at different temperatures. In the temperature range of liquid nitrogen, maximum trapped fields of 1.1 T were found at 77 K by doping of YBCO with small amounts of zinc. The improved pinning of zinc-doped YBa2Cu3O7-x (YBCO) results in a pronounced peak effect in the field dependence of the critical current density. the trapped field at lower temperatures increases due to the increasing critical current density, however, at temperatures around 50 K cracking of the material is observed which is exposed to considerably tensile stresses due to Lorentz forces. Very high trapped fields up to 14.4 T were achieved at 22.5 K for a YBCO disk pair by the addition of silver improving the tensile strength of YBCO and by using a bandage made of a steel tube. The steel tube produces a compressive stress on YBCO after cooling down from 300 K to the measuring temperature, which is due to the higher coeeficient of thermal expansion of steel compared with that of YBCO in the a,b plane. The application of superconducting permanent magnets with trapped fields of 10 T and more in superconducting bearings would allow to obtain very high levitation pressures up to 2500 N/cm2 which is two orders of magnitude higher than the levitation pressure achievable in superconducting bearings with conventional permanent magnets. The most important problem for the application of superconducting permanent magnets is the magnetizing procedure of the YBCO material. Results of magnetizing YBCO disks by using of pulsed magnetic fields will be presented.

  12. Cavitation instability in bulk metallic glasses

    Directory of Open Access Journals (Sweden)

    Dai L.H.

    2015-01-01

    Full Text Available Recent experiments have shown that fracture surfaces of bulk metallic glasses (BMGs usually exhibit an intriguing nanoscale corrugation like fractographic feature mediated by nanoscale void formation. We attribute the onset of this nanoscale corrugation to TTZs (tension transformation zones mediated cavitation. In our recent study, the spall experiments of Zr-based BMG using a single-stage light gas gun were performed. To uncover the mechanisms of the spallation damage nucleation and evolution, the samples were designed to be subjected to dynamic tensile loadings of identical amplitude but with different durations by making use of the multi-stress pulse and the double-flyer techniques. It is clearly revealed that the macroscopic spall fracture in BMGs originates from the nucleation, growth and coalescence of micro-voids. Then, a microvoid nucleation model of BMGs based on free volume theory is proposed, which indicates that the nucleation of microvoids at the early stage of spallation in BMGs is resulted from diffusion and coalescence of free volume. Furthermore, a theoretical model of void growth in BMGs undergoing remote dynamic hydrostatic tension is developed. The critical condition of cavitation instability is obtained. It is found that dynamic void growth in BMGs can be well controlled by a dimensionless inertial number characterizing the competition between intrinsic and extrinsic time scales. To unveil the atomic-level mechanism of cavitation, a systematic molecular dynamics (MD simulation of spallation behaviour of a binary metallic glass with different impact velocities was performed. It is found that micro-void nucleation is determined TTZs while the growth is controlled by shear transformation zones (STZs at atomic scale.

  13. Grafted Cross-Linked Polyolefin Substrates for Peptide Synthesis and Assays

    DEFF Research Database (Denmark)

    1999-01-01

    suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words...

  14. Trolling new media: violent extremist groups recruiting through social media

    OpenAIRE

    Chang, Mark D.

    2015-01-01

    Approved for public release; distribution is unlimited With the advent and subsequent growth of several new media technologies, violent extremist groups have incorporated social media into recruiting strategies. How are violent extremist groups using social media for recruiting? This thesis explores several new media technologies—websites, blogs, social media, mobile phones, and online gaming—to determine if violent extremist groups rely on social media for recruiting. By comparing the com...

  15. Komunikasi Krisis di Era New Media dan Social Media

    OpenAIRE

    Prastya, Narayana Mahendra

    2016-01-01

    New media and social media have changed the practice of public relations. One area that changed is crisis communication. Because of these new technologies, crisis can be more complex. The pace of information, the uncertainty, and the rumors, are increasing. Public relations practitioners should include the new media and social media use in their crisis communication plan. Before doing that, public relations practitioners should change their mindset about social media and new media. The first ...

  16. Populism and the media

    DEFF Research Database (Denmark)

    Esser, Frank; Stepinska, Agnieszka; Hopmann, David Nicolas

    2017-01-01

    European media systems have gone through major changes in the last few decades, and these changes have included increased opportunity structures for the dissemination of populist messages. Chapter 12 (‘Switzerland’) rightly states that the disappearance of the traditional party press, increased...... media ownership concentration, dependence on advertising, and a stronger orientation toward news values have worked in favor of a growing populist discourse. The newly established online media are seen as having a high afnity to populism’s rhetorical persuasion because both aim for the “quick kick....../click” with a broad audience. As was stated in Chapter 1 in this volume, the role that the media play in the dissemination of populism is largely under-explored. In the classical research literature dealing with populism (see, e.g., Canovan, 1981; Taggart, 2000), communication and media are not addressed at all. When...

  17. Media Sociography on Weblogs

    DEFF Research Database (Denmark)

    Tække, Jesper

    Weblogs are not only one of the newest technical media for communication, but also one of the most difficult to understand. Are weblogs a kind of mass medium, a personal medium like an online diary, or a medium that gives space for communities to grow? Or are weblogs a medium that enable all...... these possibilities depended on the actual use? This paper throws some light on what weblogs are by using the methodology of Media Sociography (Tække 2003, 2004a, 2004b and 2004c). Media Sociography is a strategy for analysing mediated social systems or in other words a strategy for describing the social in relation...... to the media it is based on. Theoretically seen it is inspired of two theoretical paradigms the Sociological Systems Theory of Niklas Luhmann and the Media Theory (also called the Toronto school). Empirically the paper primary draws on the literature about weblogs, which could be framed as CMC...

  18. Social Media in Organizations

    DEFF Research Database (Denmark)

    Razmerita, Liana; Kirchner, Kathrin; Nabeth, Thierry

    2014-01-01

    By using social media, many companies try to exploit new forms of interaction, collaboration, and knowledge sharing through leveraging the social, collaborative dimension of social software. The traditional collective knowledge management model based on a top-down approach is now opening up new...... avenues for a bottom-up approach incorporating a more personal knowledge management dimension, which could be synergized into collective knowledge using the social-collaborative dimension of social media. This article addresses the following questions: (1) How can social media support the management...... of personal and collective knowledge using a synergetic approach? (2) Do the personal and collective dimensions compete with each other or can they reinforce each other in a more effective manner using social media? Our findings indicate that social media supports both the personal and collective dimensions...

  19. Social Media Reputation

    DEFF Research Database (Denmark)

    Etter, Michael; Colleoni, Elanor; Ravasi, Davide

    directly to corporate performance and actions. Secondly, prominent reputation measurements couple stakeholders´ believes to reputation drivers through the use of predefined scales and items. We argue that with the rise of social media a company´s reputation has increasingly become autonomous from corporate...... actions, which demands a greater decoupling of stakeholders´ perceptions from corporate signals or actions in corporate reputation research. We develop the concept of social media reputation as the overall evaluation of a company presented in social media and present a new approach of measuring reputation...... based on social media data that accounts for the autonomy of stakeholder´s perception of a firm. We compare and contrast this novel social media reputation measure (SMRM) with traditional reputation measurements and find that SMRM is a valuable measurement to capture the autonomy of the stakeholders...

  20. Balancing media environments

    DEFF Research Database (Denmark)

    Olesen, Mogens

    The paper examines how students in Danish upper secondary schools experience the uses and effects of the digital environment in relation to their school activities. Theoretically a media ecological perspective (Strate 2006) is applied which understands teaching and learning practices as shaped...... by the interrelation between teacher, student and the media technologies. According to this perspective, media creates an environment that shapes our possibilities for acting and communicating. In a basic sense, teaching and learning is a communicative situation where, traditionally, the teacher sends information...... to the receiving students through a medium (e.g. speech, blackboard, book or online learning platform). Digital media challenge this situation due to their affordances (Gibson 1979) for interactivity. Affordance has become an increasingly popular term within media studies for describing a complementary...

  1. From media crossing to media mining

    NARCIS (Netherlands)

    de Jong, Franciska M.G.; Piperidis, S.; Cunningham, H.; Tablan, V.

    2006-01-01

    This paper reviews how the concept of Media Crossing has contributed to the advancement of the application domain of information access and explores directions for a future research agenda. These will include themes that could help to broaden the scope and to incorporate the concept of

  2. Social Justice and Media. Media Corner.

    Science.gov (United States)

    Braun, Joseph A., III, Ed.

    1994-01-01

    Contends that the end of slavery, women's suffrage, and the civil rights movement were watershed events of social justice in U.S. history. Provides reviews of two media-based sets of instructional materials that can help students understand the struggle by disenfranchised groups to become full participants in society. (CFR)

  3. 7 CFR 58.211 - Packaging room for bulk products.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging room for bulk products. 58.211 Section 58... Service 1 Rooms and Compartments § 58.211 Packaging room for bulk products. A separate room or area shall... dust within the packaging room and where needed, a dust collector shall be provided and properly...

  4. Quantifying Dustiness, Specific Allergens, and Endotoxin in Bulk Soya Imports

    Directory of Open Access Journals (Sweden)

    Howard J. Mason

    2017-11-01

    Full Text Available Soya is an important bulk agricultural product often transported by sea as chipped beans and/or the bean husks after pelletisation. There are proven allergens in both forms. Bulk handling of soya imports can generate air pollution containing dust, allergens, and pyrogens, posing health risks to dockside workers and surrounding populations. Using an International Organization for Standardization (ISO standardised rotating drum dustiness test in seven imported soya bulks, we compared the generated levels of dust and two major soya allergens in three particle sizes related to respiratory health. Extractable levels of allergen and endotoxin from the bulks showed 30–60 fold differences, with levels of one allergen (hydrophobic seed protein and endotoxin higher in husk. The generated levels of dust and allergens in the three particle sizes also showed very wide variations between bulks, with aerolysed levels of allergen influenced by both the inherent dustiness and the extractable allergen in each bulk. Percentage allergen aerolysed from pelletized husk—often assumed to be of low dustiness—after transportation was not lower than that from chipped beans. Thus, not all soya bulks pose the same inhalation health risk and reinforces the importance of controlling dust generation from handling all soya bulk to as low as reasonably practicable.

  5. Bulk photovoltaic effect in an organi c polar crystal

    NARCIS (Netherlands)

    Vijayaraghavan, R.K.; Meskers, S.C.J.; Abdul Rahim, M.; Das, S.

    2014-01-01

    Organic polar crystals from the donor–acceptor substituted 1,4-diphenybutadiene 1 can generate a short-circuit photocurrent and a photovoltage upon illumination with near UV light. The photocurrent and photovoltage are attributed to a bulk photovoltaic effect. The bulk photovoltaic effect has been

  6. Calculation and design for SSRF's bulk shield

    Energy Technology Data Exchange (ETDEWEB)

    Fang, K.M. [Shanghai Institute of Applied Physics, Chinese Academy of Science (China)]. E-mail: fangkm@sinap.ac.cn; Xu, X.J. [Shanghai Institute of Applied Physics, Chinese Academy of Science (China); Cai, J.H. [Shanghai Institute of Applied Physics, Chinese Academy of Science (China)

    2006-12-15

    Shielding design objectives for the SSRF are chosen, assumptions for beam loss rates are given, the methods used on the APS by Moe are summarized and introduced to make calculation and design on bulk shield, the factor of skyshine is also considered, design thicknesses for SSRF's bulk shield are presented.

  7. Effect of Bulk and Interfacial Rheological Properties on Bubble Dissolution

    NARCIS (Netherlands)

    Kloek, W.; Vliet, van T.; Meinders, M.

    2001-01-01

    This paper describes theoretical calculations of the combined effect of bulk and interracial rheological properties on dissolution behavior of a bubble in an infinite medium at saturated conditions. Either bulk or interracial elasticity can stop the bubble dissolution process, and stability criteria

  8. Bulk density and porosity distributions in a compost pile

    NARCIS (Netherlands)

    Ginkel, van J.T.; Raats, P.A.C.; Haneghem, van I.A.

    1999-01-01

    This paper mainly deals with the description of the initial distribution of bulk density and porosity at the moment a compost pile is built or rebuilt. A relationship between bulk density and vertical position in a pile is deduced from theoretical and empirical considerations. Formulae to calculate

  9. Role of bulking agents in bladder exstrophyepispadias complexes ...

    African Journals Online (AJOL)

    Background: Role of pelvic osteotomy in surgical management of bladder exstrophy is controversial But pelvic rim closure importantly. Bulking agents have been used for perineal and pelvic dysfunction in adults. In this study, bladder extrophy repair was performed without pubic closure And bulking agent injections were ...

  10. Bulk and edge spin transport in topological magnon insulators

    NARCIS (Netherlands)

    Rückriegel, A.; Brataas, A.; Duine, R.A.

    2018-01-01

    We investigate the spin transport properties of a topological magnon insulator, a magnetic insulator characterized by topologically nontrivial bulk magnon bands and protected magnon edge modes located in the bulk band gaps. Employing the Landau-Lifshitz-Gilbert phenomenology, we calculate the spin

  11. Influence of bulk dielectric polarization upon PD transients

    DEFF Research Database (Denmark)

    Pedersen, Aage; Crichton, George C; McAllister, Iain Wilson

    1995-01-01

    associated with the actual space charge in the void, and one related to changes in the bulk polarization brought about by changes in the field external to the void due to this space charge. The magnitude of the induced charge and its components are discussed in relation to a heterogeneous bulk dielectric...

  12. 77 FR 12293 - PCBs Bulk Product v. Remediation Waste

    Science.gov (United States)

    2012-02-29

    .... Remediation Waste AGENCY: Environmental Protection Agency (EPA). ACTION: Request for Public Comment. SUMMARY... biphenyl (PCB) disposal regulations regarding PCB bulk product and PCB remediation waste. The proposed... regarding PCB bulk product and PCB remediation waste under regulations promulgated at 40 CFR part 761. The...

  13. Automation of the dicentric chromosome assay and related assays

    International Nuclear Information System (INIS)

    Balajee, Adayabalam S.; Dainiak, Nicholas

    2016-01-01

    Dicentric Chromosome Assay (DCA) is considered to be the 'gold standard' for personalized dose assessment in humans after accidental or incidental radiation exposure. Although this technique is superior to other cytogenetic assays in terms of specificity and sensitivity, its potential application to radiation mass casualty scenarios is highly restricted because DCA is time consuming and labor intensive when performed manually. Therefore, it is imperative to develop high throughput automation techniques to make DCA suitable for radiological triage scenarios. At the Cytogenetic Biodosimetry Laboratory in Oak Ridge, efforts are underway to develop high throughput automation of DCA. Current status on development of various automated cytogenetic techniques in meeting the biodosimetry needs of radiological/nuclear incident(s) will be discussed

  14. Assay strategies and methods for phospholipases

    International Nuclear Information System (INIS)

    Reynolds, L.J.; Washburn, W.N.; Deems, R.A.; Dennis, E.A.

    1991-01-01

    Of the general considerations discussed, the two issues which are most important in choosing an assay are (1) what sensitivity is required to assay a particular enzyme and (2) whether the assay must be continuous. One can narrow the options further by considering substrate availability, enzyme specificity, assay convenience, or the presence of incompatible side reactions. In addition, the specific preference of a particular phospholipase for polar head group, micellar versus vesicular substrates, and anionic versus nonionic detergents may further restrict the options. Of the many assays described in this chapter, several have limited applicability or serious drawbacks and are not commonly employed. The most commonly used phospholipase assays are the radioactive TLC assay and the pH-stat assay. The TLC assay is probably the most accurate, sensitive assay available. These aspects often outweigh the disadvantages of being discontinuous, tedious, and expensive. The radioactive E. coli assay has become popular recently as an alternative to the TLC assay for the purification of the mammalian nonpancreatic phospholipases. The assay is less time consuming and less expensive than the TLC assay, but it is not appropriate when careful kinetics are required. Where less sensitivity is needed, or when a continuous assay is necessary, the pH-stat assay is often employed. With purified enzymes, when free thiol groups are not present, a spectrophotometric thiol assay can be used. This assay is ∼ as sensitive as the pH-stat assay but is more convenient and more reproducible, although the substrate is not available commercially. Despite the many assay choices available, the search continues for a convenient, generally applicable assay that is both sensitive and continuous

  15. Bulk viscosity of spin-one color superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Sa' d, Basil A.

    2009-08-27

    The bulk viscosity of several quark matter phases is calculated. It is found that the effect of color superconductivity is not trivial, it may suppress, or enhance the bulk viscosity depending on the critical temperature and the temperature at which the bulk viscosity is calculated. Also, is it found that the effect of neutrino-emitting Urca processes cannot be neglected in the consideration of the bulk viscosity of strange quark matter. The results for the bulk viscosity of strange quark matter are used to calculate the r-mode instability window of quark stars with several possible phases. It is shown that each possible phase has a different structure for the r-mode instability window. (orig.)

  16. Renormalization group approach to causal bulk viscous cosmological models

    International Nuclear Information System (INIS)

    Belinchon, J A; Harko, T; Mak, M K

    2002-01-01

    The renormalization group method is applied to the study of homogeneous and flat Friedmann-Robertson-Walker type universes, filled with a causal bulk viscous cosmological fluid. The starting point of the study is the consideration of the scaling properties of the gravitational field equations, the causal evolution equation of the bulk viscous pressure and the equations of state. The requirement of scale invariance imposes strong constraints on the temporal evolution of the bulk viscosity coefficient, temperature and relaxation time, thus leading to the possibility of obtaining the bulk viscosity coefficient-energy density dependence. For a cosmological model with bulk viscosity coefficient proportional to the Hubble parameter, we perform the analysis of the renormalization group flow around the scale-invariant fixed point, thereby obtaining the long-time behaviour of the scale factor

  17. Bulk velocity extraction for nano-scale Newtonian flows

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wenfei, E-mail: zwenfei@gmail.com [Key Laboratory of Mechanical Reliability for Heavy Equipments and Large Structures of Hebei Province, Yanshan University, Qinhuangdao 066004 (China); Sun, Hongyu [Key Laboratory of Mechanical Reliability for Heavy Equipments and Large Structures of Hebei Province, Yanshan University, Qinhuangdao 066004 (China)

    2012-04-16

    The conventional velocity extraction algorithm in MDS method has difficulty to determine the small flow velocity. This study proposes a new method to calculate the bulk velocity in nano-flows. Based on the Newton's law of viscosity, according to the calculated viscosities and shear stresses, the flow velocity can be obtained by numerical integration. This new method can overcome the difficulty existed in the conventional MDS method and improve the stability of the computational process. Numerical results show that this method is effective for the extraction of bulk velocity, no matter the bulk velocity is large or small. -- Highlights: ► Proposed a new method to calculate the bulk velocity in nano-flows. ► It is effective for the extraction of small bulk velocity. ► The accuracy, convergence and stability of the new method is good.

  18. Bulk velocity extraction for nano-scale Newtonian flows

    International Nuclear Information System (INIS)

    Zhang, Wenfei; Sun, Hongyu

    2012-01-01

    The conventional velocity extraction algorithm in MDS method has difficulty to determine the small flow velocity. This study proposes a new method to calculate the bulk velocity in nano-flows. Based on the Newton's law of viscosity, according to the calculated viscosities and shear stresses, the flow velocity can be obtained by numerical integration. This new method can overcome the difficulty existed in the conventional MDS method and improve the stability of the computational process. Numerical results show that this method is effective for the extraction of bulk velocity, no matter the bulk velocity is large or small. -- Highlights: ► Proposed a new method to calculate the bulk velocity in nano-flows. ► It is effective for the extraction of small bulk velocity. ► The accuracy, convergence and stability of the new method is good.

  19. Temperature dependence of bulk viscosity in water using acoustic spectroscopy

    International Nuclear Information System (INIS)

    Holmes, M J; Parker, N G; Povey, M J W

    2011-01-01

    Despite its fundamental role in the dynamics of compressible fluids, bulk viscosity has received little experimental attention and there remains a paucity of measured data. Acoustic spectroscopy provides a robust and accurate approach to measuring this parameter. Working from the Navier-Stokes model of a compressible fluid one can show that the bulk viscosity makes a significant and measurable contribution to the frequency-squared acoustic attenuation. Here we employ this methodology to determine the bulk viscosity of Millipore water over a temperature range of 7 to 50 0 C. The measured attenuation spectra are consistent with the theoretical predictions, while the bulk viscosity of water is found to be approximately three times larger than its shear counterpart, reinforcing its significance in acoustic propagation. Moreover, our results demonstrate that this technique can be readily and generally applied to fluids to accurately determine their temperature dependent bulk viscosities.

  20. Bulk viscosity of spin-one color superconductors

    International Nuclear Information System (INIS)

    Sa'd, Basil A.

    2009-01-01

    The bulk viscosity of several quark matter phases is calculated. It is found that the effect of color superconductivity is not trivial, it may suppress, or enhance the bulk viscosity depending on the critical temperature and the temperature at which the bulk viscosity is calculated. Also, is it found that the effect of neutrino-emitting Urca processes cannot be neglected in the consideration of the bulk viscosity of strange quark matter. The results for the bulk viscosity of strange quark matter are used to calculate the r-mode instability window of quark stars with several possible phases. It is shown that each possible phase has a different structure for the r-mode instability window. (orig.)

  1. Analysis of long-term monomer elution from bulk-fill and conventional resin-composites using high performance liquid chromatography.

    Science.gov (United States)

    Alshali, Ruwaida Z; Salim, Nesreen A; Sung, Rehana; Satterthwaite, Julian D; Silikas, Nick

    2015-12-01

    The aim of this study was to assess monomer elution from bulk-fill and conventional resin-composites stored in different media using high performance liquid chromatography (HPLC) for up to 3 months. Six bulk-fill (SureFil SDR, Venus Bulk Fill, X-tra base, Filtek Bulk Fill flowable, Sonic Fill, and Tetric EvoCeram Bulk Fill) and eight conventional resin-composites (Grandioso Flow, Venus Diamond Flow, X-Flow, Filtek Supreme XTE, Grandioso, Venus Diamond, TPH Spectrum, and Filtek Z250) were tested. Cylindrical samples (n=5) were immersed in water, 70% ethanol/water solution (70% E/W), and artificial saliva and stored at 37°C for 24h, 1 month, and 3 months. The storage solutions were analysed with HPLC. Data were analysed with repeated measures ANOVA, one-way ANOVA, and Tukey post hoc test at α=0.05. Monomers detected in water and artificial saliva were TEGDMA, DEGDMA, UDMA, and TCD-DI-HEA. No eluted monomers were detected from X-tra base and Sonic fill in these media. All monomers showed a variable extent of elution into 70% E/W with significantly higher amounts than those detected in water and artificial saliva. Significantly higher elution was detected from UDMA-BisEMA based composites compared to BisGMA and BisGMA-BisEMA based systems in 70% E/W. The rate of elution into different media varied between different monomers and was highly dependent on the molecular weight of the eluted compounds. Elution from bulk-fill resin-composites is comparable to that of conventional materials despite their increased increment thickness. Monomer elution is highly dependent on the hydrophobicity of the base monomers and the final network characteristics of the resin-matrix. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  2. Social media modeling and computing

    CERN Document Server

    Hoi, Steven CH; Boll, Susanne; Xu, Dong; Jin, Rong; King, Irwin

    2011-01-01

    Presents contributions from an international selection of preeminent experts in the field Discusses topics on social-media content analysis, and examines social-media system design and analysis Describes emerging applications of social media

  3. Bullying and social media affordances

    OpenAIRE

    Brailas, Alexios

    2016-01-01

    What constitutes a good and sustainabledigital living?Social media literacyCan we talk about social media intelligence?Can we talk about digital intelligence?How bullying is complicated by special social media affordances?

  4. MediaTracker system

    Energy Technology Data Exchange (ETDEWEB)

    Sandoval, D. M. (Dana M.); Strittmatter, R. B. (Richard B.); Abeyta, J. D. (Joline D.); Brown, J. (John); Marks, T. (Thomas), Jr.; Martinez, B. J. (Benny J.); Jones, D. B. (Dana Benelli); Hsue, W.

    2004-01-01

    The initial objectives of this effort were to provide a hardware and software platform that can address the requirements for the accountability of classified removable electronic media and vault access logging. The Media Tracker system software assists classified media custodian in managing vault access logging and Media Tracking to prevent the inadvertent violation of rules or policies for the access to a restricted area and the movement and use of tracked items. The MediaTracker system includes the software tools to track and account for high consequence security assets and high value items. The overall benefits include: (1) real-time access to the disposition of all Classified Removable Electronic Media (CREM), (2) streamlined security procedures and requirements, (3) removal of ambiguity and managerial inconsistencies, (4) prevention of incidents that can and should be prevented, (5) alignment with the DOE's initiative to achieve improvements in security and facility operations through technology deployment, and (6) enhanced individual responsibility by providing a consistent method of dealing with daily responsibilities. In response to initiatives to enhance the control of classified removable electronic media (CREM), the Media Tracker software suite was developed, piloted and implemented at the Los Alamos National Laboratory beginning in July 2000. The Media Tracker software suite assists in the accountability and tracking of CREM and other high-value assets. One component of the MediaTracker software suite provides a Laboratory-approved media tracking system. Using commercial touch screen and bar code technology, the MediaTracker (MT) component of the MediaTracker software suite provides an efficient and effective means to meet current Laboratory requirements and provides new-engineered controls to help assure compliance with those requirements. It also establishes a computer infrastructure at vault entrances for vault access logging, and can

  5. MediaTracker system

    International Nuclear Information System (INIS)

    Sandoval, D.M.; Strittmatter, R.B.; Abeyta, J.D.; Brown, J.; Marks, T. Jr.; Martinez, B.J.; Jones, D.B.; Hsue, W.

    2004-01-01

    The initial objectives of this effort were to provide a hardware and software platform that can address the requirements for the accountability of classified removable electronic media and vault access logging. The Media Tracker system software assists classified media custodian in managing vault access logging and Media Tracking to prevent the inadvertent violation of rules or policies for the access to a restricted area and the movement and use of tracked items. The MediaTracker system includes the software tools to track and account for high consequence security assets and high value items. The overall benefits include: (1) real-time access to the disposition of all Classified Removable Electronic Media (CREM), (2) streamlined security procedures and requirements, (3) removal of ambiguity and managerial inconsistencies, (4) prevention of incidents that can and should be prevented, (5) alignment with the DOE's initiative to achieve improvements in security and facility operations through technology deployment, and (6) enhanced individual responsibility by providing a consistent method of dealing with daily responsibilities. In response to initiatives to enhance the control of classified removable electronic media (CREM), the Media Tracker software suite was developed, piloted and implemented at the Los Alamos National Laboratory beginning in July 2000. The Media Tracker software suite assists in the accountability and tracking of CREM and other high-value assets. One component of the MediaTracker software suite provides a Laboratory-approved media tracking system. Using commercial touch screen and bar code technology, the MediaTracker (MT) component of the MediaTracker software suite provides an efficient and effective means to meet current Laboratory requirements and provides new-engineered controls to help assure compliance with those requirements. It also establishes a computer infrastructure at vault entrances for vault access logging, and can accommodate

  6. The formation and growing properties of poly(ethylene terephthalate) fiber growing media after thermo-oxidative treatment

    International Nuclear Information System (INIS)

    Chang, C.P.; Lin, S.M.

    2007-01-01

    This research uses three kinds of recycled synthetic fibers that all possess excellent thermal plasticity property as raw material to develop a new firm cultivation media: polyethylene terephthalate, polyamide and polypropylene. One can not only freely control plants cultivation growing condition by changing bulk density of the media, but also solve disposal problem after usage by applying thermal oxidative treatment during manufacturing processes. The water content, air permeability and formation conditions of these fiber growing media that are required in plants growing habitat were discussed, and compared the fallout with rockwool (RW) growing media that is commonly used at present days. The results indicated that the polyethylene terephthalate fiber media could attain best formation characteristics among these fibers at the same bulk density range. Furthermore, the fiber media that were thermo-oxidative treated at 240-260 deg. C could obtained above 90% total porosity, 23-49% air capacity and 48-68% water availability, water contents raised from 1735-1094 to 2145-1156% under bulk densities of 0.03-0.09 g/cm 3 , which conforms to the common plant growing habitat conditions. Its performance well surpasses the rockwool growing media. We also discovered that the thermo-oxidative treated polyethylene terephthalate (PET) fiber media could be easily broken down and become powdery by exerting pressure, thus greatly reduce its volume and effectively improve disposal processes that are difficult presently for the huge refuse create by rockwool

  7. Social Media Marketing in Russia

    OpenAIRE

    Olgskaya, Kristina

    2017-01-01

    Social media marketing involves the use of social media for connecting with prospective consumers. The study focuses on explaining such notions like social media marketing (SMM), types of SMM, differences between social media and traditional marketing, social media marketing plan, development ways of strategic social media marketing plan and why strategy may fail. This thesis also presents research in Russian social network – Vkontakte, where promotion of Mechanical Engineering programme ...

  8. Disinfection ultraviolet radiation bulk food products

    OpenAIRE

    Семенов, А. А.

    2014-01-01

    В работе представлены результаты обеззараживания сыпучих пищевых продуктов ультрафиолетовым излучением. Предложена технология бактерицидного обеззараживания сыпучих продуктов с размером частиц до 50 мкм. Проведены необходимые расчеты, связанные с дозой облучения, с временем пребывания частиц в зоне облучения и необходимой дозой инактивации в зависимости от вида бактерий. Considered the results of bulk food products disinfection by ultraviolet radiation. The technology bactericidal disinfec...

  9. Stability of bulk metallic glass structure

    Energy Technology Data Exchange (ETDEWEB)

    Jain, H.; Williams, D.B.

    2003-06-18

    The fundamental origins of the stability of the (Pd-Ni){sub 80}P{sub 20} bulk metallic glasses (BMGs), a prototype for a whole class of BMG formers, were explored. While much of the properties of their BMGs have been characterized, their glass-stability have not been explained in terms of the atomic and electronic structure. The local structure around all three constituent atoms was obtained, in a complementary way, using extended X-ray absorption fine structure (EXAFS), to probe the nearest neighbor environment of the metals, and extended energy loss fine structure (EXELFS), to investigate the environment around P. The occupied electronic structure was investigated using X-ray photoelectron spectroscopy (XPS). The (Pd-Ni){sub 80}P{sub 20} BMGs receive their stability from cumulative, and interrelated, effects of both atomic and electronic origin. The stability of the (Pd-Ni){sub 80}P{sub 20} BMGs can be explained in terms of the stability of Pd{sub 60}Ni{sub 20}P{sub 20} and Pd{sub 30}Ni{sub 50}P{sub 20}, glasses at the end of BMG formation. The atomic structure in these alloys is very similar to those of the binary phosphide crystals near x=0 and x=80, which are trigonal prisms of Pd or Ni atoms surrounding P atoms. Such structures are known to exist in dense, randomly-packed systems. The structure of the best glass former in this series, Pd{sub 40}Ni{sub 40}P{sub 20} is further described by a weighted average of those of Pd{sub 30}Ni{sub 50}P{sub 20} and Pd{sub 60}Ni{sub 20}P{sub 20}. Bonding states present only in the ternary alloys were found and point to a further stabilization of the system through a negative heat of mixing between Pd and Ni atoms. The Nagel and Tauc criterion, correlating a decrease in the density of states at the Fermi level with an increase in the glass stability, was consistent with greater stability of the Pd{sub x}Ni{sub (80-x)}P{sub 20} glasses with respect to the binary alloys of P. A valence electron concentration of 1.8 e/a, which

  10. CLASSICAL MEDIA RELATIONS AND NEW MEDIA RELATIONS IN SPORT

    Directory of Open Access Journals (Sweden)

    Alexandru Lucian MIHAI

    2014-06-01

    Full Text Available Media relations in sport mean maintenance of networks and positive relationships with people in the media to obtain positive media exposure for a sport product (informal and formal information sessions with media representatives. Because of the pervasive influence the media has on marketing success, sport marketers must make concerted efforts to create a positive relationship between their sport event and the media. They may accomplish this by providing the media with press releases, having news conferences, having media-day events (in which the media are invited to interact with the players, coaches, and administrators, providing media guides for the respective sport events and so on. Each of these activities promotes active involvement from the media, which will subsequently contribute to relationship building with the community.

  11. Studies of nonlinear femtosecond pulse propagation in bulk materials

    Science.gov (United States)

    Eaton, Hilary Kaye

    2000-10-01

    Femtosecond pulse lasers are finding widespread application in a variety of fields including medical research, optical switching and communications, plasma formation, high harmonic generation, and wavepacket formation and control. As the number of applications for femtosecond pulses increases, so does the need to fully understand the linear and nonlinear processes involved in propagating these pulses through materials under various conditions. Recent advances in pulse measurement techniques, such as frequency-resolved optical gating (FROG), allow measurement of the full electric field of the pulse and have made detailed investigations of short- pulse propagation effects feasible. In this thesis, I present detailed experimental studies of my work involving nonlinear propagation of femtosecond pulses in bulk media. Studies of plane-wave propagation in fused silica extend the SHG form of FROG from a simple pulse diagnostic to a useful method of interrogating the nonlinear response of a material. Studies of nonlinear propagation are also performed in a regime where temporal pulse splitting occurs. Experimental results are compared with a three- dimensional nonlinear Schrödinger equation. This comparison fuels the development of a more complete model for pulse splitting. Experiments are also performed at peak input powers above those at which pulse splitting is observed. At these higher intensities, a broadband continuum is generated. This work presents a detailed study of continuum behavior and power loss as well as the first near-field spatial- spectral measurements of the generated continuum light. Nonlinear plane-wave propagation of short pulses in liquids is also investigated, and a non-instantaneous nonlinearity with a surprisingly short response time of 10 fs is observed in methanol. Experiments in water confirm that this effect in methanol is indeed real. Possible explanations for the observed effect are discussed and several are experimentally rejected. This

  12. Social Media and Bullshit

    Directory of Open Access Journals (Sweden)

    Rasmus Kleis Nielsen

    2015-04-01

    Full Text Available To understand the role of social media in society, we have to understand how social media are understood. We need to analyze how different actors and organizations see and think about technology, the forms of knowledge that people draw on as they make sense of, develop, and use social media. Central among these is bullshit. This short essay discusses bullshit as defined by the philosopher Harry Frankfurt as statements made with little or no concern for their truth-value or justification and argues that social media are accompanied by unusually large amounts of bullshit for two reasons. First, they confront us with epistemological problems and are hard to understand. Second, there is a large demand for knowledge about what they mean, a powerful political economy that generates a lot of statements about social media, including substantial amounts of bullshit. Given the rapid development of social media and their growing importance, this is unlikely to change in the near future. Bullshit is here to stay, and we need to take it seriously intellectually and analytically to understand social media.

  13. Media Literacy in Montenegro

    Directory of Open Access Journals (Sweden)

    Jelena Perovic

    2015-12-01

    Full Text Available Few countries in the world have introduced media education into their curriculums. Montenegro became one of them in 2009, when “media literacy” was introduced as an optional subject for 16 and 17 year old students of Gymnasium high schools. This article presents the findings of the first and only research conducted so far on media education in Montenegro. It is a national case study which examines the potential of media education to change the school culture and accelerate education system reform towards embracing the new digital education paradigm in the future. The focus is on the results of research conducted through in-depth interviews with media literacy teachers all over the country. Despite the many challenges, all teachers identify the potential of media education to strengthen some of the key competences of the students and to improve their motivation and academic performance. They also identify potential to change positively school culture by transforming teachers into “cultural mediators” (Morcellini, 2007 and by supporting the formation of a “participative culture” (Jenkins & Kelley, 2013 in schools. This research recommends focusing education reform on spreading the media education pedagogy to the entire curriculum in order to embrace the new digital education paradigm in the future.

  14. Development and Fit-for-Purpose Validation of a Soluble Human Programmed Death-1 Protein Assay.

    Science.gov (United States)

    Ni, Yan G; Yuan, Xiling; Newitt, John A; Peterson, Jon E; Gleason, Carol R; Haulenbeek, Jonathan; Santockyte, Rasa; Lafont, Virginie; Marsilio, Frank; Neely, Robert J; DeSilva, Binodh; Piccoli, Steven P

    2015-07-01

    Programmed death-1 (PD-1) protein is a co-inhibitory receptor which negatively regulates immune cell activation and permits tumors to evade normal immune defense. Anti-PD-1 antibodies have been shown to restore immune cell activation and effector function-an exciting breakthrough in cancer immunotherapy. Recent reports have documented a soluble form of PD-1 (sPD-1) in the circulation of normal and disease state individuals. A clinical assay to quantify sPD-1 would contribute to the understanding of sPD-1-function and facilitate the development of anti-PD-1 drugs. Here, we report the development and validation of a sPD-1 protein assay. The assay validation followed the framework for full validation of a biotherapeutic pharmacokinetic assay. A purified recombinant human PD-1 protein was characterized extensively and was identified as the assay reference material which mimics the endogenous analyte in structure and function. The lower limit of quantitation (LLOQ) was determined to be 100 pg/mL, with a dynamic range spanning three logs to 10,000 pg/mL. The intra- and inter-assay imprecision were ≤15%, and the assay bias (percent deviation) was ≤10%. Potential matrix effects were investigated in sera from both normal healthy volunteers and selected cancer patients. Bulk-prepared frozen standards and pre-coated Streptavidin plates were used in the assay to ensure consistency in assay performance over time. This assay appears to specifically measure total sPD-1 protein since the human anti-PD-1 antibody, nivolumab, and the endogenous ligands of PD-1 protein, PDL-1 and PDL-2, do not interfere with the assay.

  15. Turkish Press in Social Media

    OpenAIRE

    AYTEN, Adem

    2013-01-01

    Social media, is one of the most researched facts today by the commications fellows. To get in use by Web 2.0 social media becomes common due to the rise of using mobile technologies. Instead of competing with traditional media and being an alternative media, social media is a new media that traditional media can transfer its content to it and can benefit its advantages. Indeed,the traditional media carried its content to the websites to access of their readers/listeners/watchers to compete ...

  16. Media multitasking and implicit learning.

    Science.gov (United States)

    Edwards, Kathleen S; Shin, Myoungju

    2017-07-01

    Media multitasking refers to the simultaneous use of different forms of media. Previous research comparing heavy media multitaskers and light media multitaskers suggests that heavy media multitaskers have a broader scope of attention. The present study explored whether these differences in attentional scope would lead to a greater degree of implicit learning for heavy media multitaskers. The study also examined whether media multitasking behaviour is associated with differences in visual working memory, and whether visual working memory differentially affects the ability to process contextual information. In addition to comparing extreme groups (heavy and light media multitaskers) the study included analysis of people who media multitask in moderation (intermediate media multitaskers). Ninety-four participants were divided into groups based on responses to the media use questionnaire, and completed the contextual cueing and n-back tasks. Results indicated that the speed at which implicit learning occurred was slower in heavy media multitaskers relative to both light and intermediate media multitaskers. There was no relationship between working memory performance and media multitasking group, and no relationship between working memory and implicit learning. There was also no evidence for superior performance of intermediate media multitaskers. A deficit in implicit learning observed in heavy media multitaskers is consistent with previous literature, which suggests that heavy media multitaskers perform more poorly than light media multitaskers in attentional tasks due to their wider attentional scope.

  17. Nondestructive assay of sale materials

    International Nuclear Information System (INIS)

    Rodenburg, W.W.; Fleissner, J.G.

    1981-01-01

    This paper covers three primary areas: (1) reasons for performing nondestructive assay on SALE materials; (2) techniques used; and (3) discussion of investigators' revised results. The study shows that nondestructive calorimetric assay of plutonium offers a viable alternative to traditional wet chemical techniques. For these samples, the precision ranged from 0.4 to 0.6% with biases less than 0.2%. Thus, for those materials where sampling errors are the predominant source of uncertainty, this technique can provide improved accuracy and precision while saving time and money as well as reducing the amount of liquid wastes to be handled. In addition, high resolution gamma-ray spectroscopy measurements of solids can provide isotopic analysis data in a cost effective and timely manner. The timeliness of the method can be especially useful to the plant operator for production control and quality control measurements

  18. Comet Assay in Cancer Chemoprevention.

    Science.gov (United States)

    Santoro, Raffaela; Ferraiuolo, Maria; Morgano, Gian Paolo; Muti, Paola; Strano, Sabrina

    2016-01-01

    The comet assay can be useful in monitoring DNA damage in single cells caused by exposure to genotoxic agents, such as those causing air, water, and soil pollution (e.g., pesticides, dioxins, electromagnetic fields) and chemo- and radiotherapy in cancer patients, or in the assessment of genoprotective effects of chemopreventive molecules. Therefore, it has particular importance in the fields of pharmacology and toxicology, and in both environmental and human biomonitoring. It allows the detection of single strand breaks as well as double-strand breaks and can be used in both normal and cancer cells. Here we describe the alkali method for comet assay, which allows to detect both single- and double-strand DNA breaks.

  19. Radioreceptor assay for somatomedin A

    Energy Technology Data Exchange (ETDEWEB)

    Takano, K [Tokyo Women' s Medical Coll. (Japan)

    1975-04-01

    Measurement method of somatomedian A by radioreceptor assay using the human placenta membrane was described and discussed. Binding rate of /sup 125/I-somatomedin A to its receptors was studied under various conditions of time and temperature of the incubation, and pH of the system. The influence of somatomedin A, porcine insulin, and porcine calcitonin, on /sup 125/I-somatomedin A bound receptors was studied, and these hormones showed the competitive binding to somatomedin A receptors in some level. The specificity, recovery rate, and clinical applications of somatomedin A were also discussed. Radioreceptor assay for somatomedine A provided easier, faster, and more accurate measurements than conventional bioassay. This technique would be very useful to study somatomedin A receptor and functions of insulin.

  20. Ethics and social media.

    Science.gov (United States)

    Milton, Constance L

    2014-10-01

    Nurses' use of social media has increased significantly with growing numbers of media-sharing opportunities, platforms, and emerging forms of electronic applications. With the proliferation, opportunities and limitations surface regarding the responsibilities and accountability that nurses have in choosing technology applications with an embedded philosophical ethos that is consistent with the discipline's societal mandate of serving humankind in ways that honor human dignity. This article begins a discussion addressing possible disciplinary obligations and responsibilities for the implementation of social media platforms and possible implications for its future use in the discipline of nursing. © The Author(s) 2014.

  1. Media and ICT

    DEFF Research Database (Denmark)

    Media and information and communication technologies (ICTs) have in the past decades been placed firmly on the educational agenda, and will continue to maintain this position, not least as catalysts for educational change. This issue is reflected in the anthology as it aims to respond...... to the question of how the presence of media and ICT in and outside schools both change and qualify educational practice as well as how the cooperation between media, cultures, aesthetics and social relations affect and support new demands on education. The book represents different academic perspectives...

  2. Open Media Science

    DEFF Research Database (Denmark)

    Møller Moltke Martiny, Kristian; Pedersen, David Budtz; Hansted, Allan Alfred Birkegaard

    2016-01-01

    In this article, we present three challenges to the emerging Open Science (OS) movement: the challenge of communication, collaboration and cultivation of scientific research. We argue that to address these challenges OS needs to include other forms of data than what can be captured in a text...... and extend into a fully-fledged Open Media movement engaging with new media and non-traditional formats of science communication. We discuss two cases where experiments with open media have driven new collaborations between scientists and documentarists. We use the cases to illustrate different advantages...

  3. Assay of vitamin B12

    International Nuclear Information System (INIS)

    Tovey, K.C.; Carrick, D.T.

    1982-01-01

    A radioassay is described for vitamin B12 which involves denaturing serum protein binding proteins with alkali. In the denaturation step a dithiopolyol and cyanide are used and in the intrinsic factor assay step a vitamin B12 analogue such as cobinamide is used to bind with any remaining serum proteins. The invention also includes a kit in which the dithiopolyol is provided in admixture with the alkali. The dithiopolyol may be dithiothreitol or dithioerythritol. (author)

  4. Assay of ribulose bisphosphate carboxylase

    International Nuclear Information System (INIS)

    Pike, C.; Berry, J.

    1987-01-01

    Assays of ribulose bisphosphate carboxylase (rubisco) can be used to illustrate many properties of photosynthetic systems. Many different leaves have been assayed with this standard procedure. The tissue is ground with a mortar and pestle in extraction buffer. The supernatant after centrifugation is used as the source of enzyme. Buffer, RuBP, [ 14 C]-NaHCO 3 , and enzyme are combined in a scintillation vial; the reaction is run for 1 min at 30 0 . The acid-stable products are counted. Reproducibility in student experiments has been excellent. The assay data can be combined with analyses of leaf properties such as fresh and dry weight, chlorophyll and protein content, etc. Students have done projects such as the response of enzyme to temperature and to various inhibitors. They also report on the use of a transition state analog, carboxyarabinitol bisphosphate, to titrate the molar concentration of rubisco molecules (active sites) in an enzyme sample. Thus, using crude extracts the catalytic activity of a sample can be compared to the absolute quantity of enzyme or to the turnover number

  5. A droplet digital PCR (ddPCR) assay to detect Helicoverpa armigera (Lepidoptera: Noctuidae) in bulk trap samples

    Science.gov (United States)

    Moths in the genus Helicoverpa are some of the most important agricultural pests in the world. Two species, H. armigera (Hübner) and H. zea (Boddie), cause the majority of damage to crops and millions of dollars are spent annually on control of these pests. The recent introduction of H. armigera int...

  6. [Amylase production by Aureobasidium pullulans in liquid and solid media].

    Science.gov (United States)

    Lodato, P B; Forchiassin, F; Segovia de Huergo, M B

    1997-01-01

    Amylase production by a strain of Aureobasidium pullulans isolated in the laboratory was evaluated in liquid media (complex and synthetic) and in solid medium (wheat bran). There was an inhibitory effect in amylase production or amylase secretion by glucose. Asparagine was the best nitrogen source for amylase production (4-6 g/l). Only chlamidospores and melanin but not, amylase activity, were obtained with ammonium sulfate. Amylase production in solid culture was higher than the production obtained in the liquid media assayed. Optimum initial moisture content in solid culture ranged between 57 and 74%. No difference was observed in amylase production between solid media inoculated with cells grown in liquid or solid media.

  7. Homogenization of discrete media

    International Nuclear Information System (INIS)

    Pradel, F.; Sab, K.

    1998-01-01

    Material such as granular media, beam assembly are easily seen as discrete media. They look like geometrical points linked together thanks to energetic expressions. Our purpose is to extend discrete kinematics to the one of an equivalent continuous material. First we explain how we build the localisation tool for periodic materials according to estimated continuum medium type (classical Cauchy, and Cosserat media). Once the bridge built between discrete and continuum media, we exhibit its application over two bidimensional beam assembly structures : the honey comb and a structural reinforced variation. The new behavior is then applied for the simple plan shear problem in a Cosserat continuum and compared with the real discrete solution. By the mean of this example, we establish the agreement of our new model with real structures. The exposed method has a longer range than mechanics and can be applied to every discrete problems like electromagnetism in which relationship between geometrical points can be summed up by an energetic function. (orig.)

  8. Spotlight on the media

    CERN Multimedia

    2007-01-01

    Do you want to know more about how the media works, how to deal with journalists? How to maximise opportunity and minimise threat? Then please join us on 22 November. This session will cover how to work effectively with the media, including print, radio and TV. You’ll get an insight into how journalists and news rooms operate. You’ll learn to recognise both soft balls and traps - and develop the techniques for dealing with them. The challenges of explaining CERN to any media outlet will be dealt with too. This interactive presentation, given by Jessica Pryce-Jones, Managing Director of the consultancy firm iOpener Ltd, and Nisha Pillai, news anchor for BBC World, will be illustrated with various case studies. How to deal with the media: maximising opportunity and minimising threat Thursday 22 November, from 4.30 pm, Main Auditorium, Bldg. 500 Coffee break before the event at 4.00 pm

  9. Technetium Sorption Media Review

    International Nuclear Information System (INIS)

    Duncan, J.B.; Kelly, S.E.; Robbins, R.A.; Adams, R.D.; Thorson, M.A.; Haass, C.C.

    2011-01-01

    This report presents information and references to aid in the selection of 99Tc sorption media for feasibility studies regarding the removal of 99Tc from Hanford's low activity waste. The report contains literature search material for sorption media (including ion exchange media) for the most tested media to date, including SuperLig 639, Reillex HPQ, TAM (Kruion), Purolite A520E and A530E, and Dowex 1X8. The U.S. Department of Energy (DOE), Office of River Protection (ORP) is responsible for management and completion of the River Protection Project (RPP) mission, which comprises both the Hanford Site tank farms and the Waste Treatment and Immobilization Plant (WTP). The RPP mission is to store, retrieve and treat Hanford's tank waste; store and dispose of treated wastes; and close the tank farm waste management areas and treatment facilities in a safe, environmentally compliant, cost-effective and energy-effective manner.

  10. New Media as Software

    Directory of Open Access Journals (Sweden)

    Manuel Portela

    2014-03-01

    Full Text Available Review of Lev Manovich, Software Takes Command: Extending the Language of New Media. London: Bloomsbury, 2013, 358 pp. ISBN 978-1-6235-6817-7. In Lev Manovich’s most recent book, this programmatic interrogation of our medial condition leads to the following question: do media still exist after software? This is the question that triggers Manovich’s dialogue both with computing history and with theories of digital media of recent decades, including the extension of his own previous formulations in The Language of New Media, published in 2001, and which became a major reference work in the field. The subtitle of the new book points precisely to this critical revisiting of his earlier work in the context of ubiquitous computing and accelerated transcoding of social, cultural and artistic practices by software.

  11. Creative Digital Media Practices

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    , 2006, 2009), machinima (machine + cinema + anime, real-time animation captured in games etc.), and the digital storytelling movement. A dialogic perspective on the diversity of digital media practices opens up for understanding the complex evolution of language on socio-historical, cultural......The presentation reviews the interplay of dialogic (Bakhtin, 1981) and multimodal theories on media production practices, with attention to visual communication (Kress and van Leeuwen, 2001, 2006). This theoretical approach aids in reflecting on digital media practices as novel (new) sign systems...... develop a collaborative digital storytelling showcase for their own digital stories about Roskilde University. This course is intended to bring up reflections on the wider phenomenon of contemporary media practices, such as: YouTube, DIY (do-it-yourself) filmmaking or homemade, garage cinema (Jenkins...

  12. Stochastic porous media equations

    CERN Document Server

    Barbu, Viorel; Röckner, Michael

    2016-01-01

    Focusing on stochastic porous media equations, this book places an emphasis on existence theorems, asymptotic behavior and ergodic properties of the associated transition semigroup. Stochastic perturbations of the porous media equation have reviously been considered by physicists, but rigorous mathematical existence results have only recently been found. The porous media equation models a number of different physical phenomena, including the flow of an ideal gas and the diffusion of a compressible fluid through porous media, and also thermal propagation in plasma and plasma radiation. Another important application is to a model of the standard self-organized criticality process, called the "sand-pile model" or the "Bak-Tang-Wiesenfeld model". The book will be of interest to PhD students and researchers in mathematics, physics and biology.

  13. Terrorism as Media Event

    Directory of Open Access Journals (Sweden)

    2012-07-01

    Full Text Available Proving that terrorism should be seen as a media event (as defined by Dayan and Katzafter 9/11 and treated accordingly. We have turned to the work of Dayan and Katz and GeorgeGerbner’s for a definition of media events and of violence in the mass media. This paper is ahermeneutical interpretation of the concept of terrorism and its relation to communication. We haveput forward a better understanding of the complex concept of terrorism and its definitions in the massmedia context. Terrorism nowadays should always be defined within its inherent relation with themedia. The article is the first to define terrorism as media evenit in Dayan and Katz’s terms.

  14. TECHNETIUM SORPTION MEDIA REVIEW

    Energy Technology Data Exchange (ETDEWEB)

    DUNCAN JB; KELLY SE; ROBBINS RA; ADAMS RD; THORSON MA; HAASS CC

    2011-08-25

    This report presents information and references to aid in the selection of 99Tc sorption media for feasibility studies regarding the removal of 99Tc from Hanford's low activity waste. The report contains literature search material for sorption media (including ion exchange media) for the most tested media to date, including SuperLig 639, Reillex HPQ, TAM (Kruion), Purolite A520E and A530E, and Dowex 1X8. The U.S. Department of Energy (DOE), Office of River Protection (ORP) is responsible for management and completion of the River Protection Project (RPP) mission, which comprises both the Hanford Site tank farms and the Waste Treatment and Immobilization Plant (WTP). The RPP mission is to store, retrieve and treat Hanford's tank waste; store and dispose of treated wastes; and close the tank farm waste management areas and treatment facilities in a safe, environmentally compliant, cost-effective and energy-effective manner.

  15. Media, journalism, objectivity

    Directory of Open Access Journals (Sweden)

    Vlajki Emil

    2013-01-01

    Full Text Available This is the text around the themes: Media and Journalism, are confronted two directions of opinions: humanism and elitism. Humanism believes that media and journalism must be metaphysically objective: able to tell the truth regardless of time, place and terms of events. Another approach, elitism, is connected with Hegel's philosophy of history. Hegel's conceptual apparatus includes: Idea, History dialectic, 'cunning mind,' self- development and self-realization. In this context, media and journalism are considered as organic unity, an inseparable part of some dialectical totality. More specifically media and journalism can be objective only if they defend concrete ideological assumptions of society to which they belong. Any other understanding of these two concepts is non-objective, mere moralizing and / or demagoguery.

  16. Media and manipulation

    Directory of Open Access Journals (Sweden)

    Kovačević Braco

    2013-01-01

    Full Text Available The role and importance of the media are huge, both in everyday life and in cultural, spiritual and political life of modern man. Their power in the sense of political shaping of people and shaping of public opinion is very distinctive. In the process of propaganda to influence public opinion, they use various manipulative procedures in order to accomplish certain interests and objectives. Through the media, politics realizes its economic, ideological, political and even military activities. The war in the former Yugoslavia and former Bosnia and Herzegovina was also waged through the media. This media war still is spreading the hate speech, thus still causing conflicts and disintegration processes in the Balkans.

  17. Media and Security Team

    Data.gov (United States)

    Federal Laboratory Consortium — The Media And Security Team led by Prof. Min Wu was established in Fall 2001 at University of Maryland, College Park. A number of research and education activities...

  18. Social Media Policies

    DEFF Research Database (Denmark)

    Stohl, Cynthia; Etter, Michael; Banghart, Scott

    2017-01-01

    of these trends is examined through a content analysis of 112 publicly available social media policies from the largest corporations in the world. The extent to which social media policies facilitate and/or constrain the communicative sensibilities and values associated with contemporary notions of CSR...... negotiation and participation in the social responsibilities of corporations. Moreover, policies generally enact organizational communication practices that are contrary to international CSR guidelines (e.g., the UN Global Compact and other international agreements). Findings suggest that social media...... policies represent a relatively unrecognized development in the institutionalization of CSR communicative norms and practices that call into question the promising affordances of social media for the inclusion of various voices in the public negotiation of what constitutes corporate social responsibility....

  19. Social Media and Teaching

    DEFF Research Database (Denmark)

    Tække, Jesper; Paulsen, Michael

    New research in the Danish upper secondary schools shows that social media like Facebook is the number one attention diverts from the interaction about educational subjects in the classroom. At the same time international research shows that there is a great potential in using social media....... The overriding purpose of the paper is to provide a research-based input to the discussion about the role of social media in schools....... the past seven years (Paulsen & Tække 2009, 2010; Tække & Paulsen 2010). To find out if and how the gap can be reduced, we have initiated the action research project The Socio Media Education Experiment, and in the paper we explain both the background for the project and its preliminary results...

  20. Consolidating Social Media Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Munar, Ana Maria; Larson, Mia

    2014-01-01

    This study revisits and integrates the insights of recent studies on emergent social media strategies deployed by destination and event management organisations. In a comparative analysis Munar (2012) identified four generic approaches pursued by national tourism boards in the Nordic region, while...... Gyimóthy & Larson (2014) portrayed three digital value co-creation strategies deployed by festival social media. Both frameworks provided novel analytical typologies which identified a series of categories (mimetic, analytic, immersion, advertising and insourcing, crowdsourcing and community consolidation......). This paper discusses the complementary nature of these conceptual proposals and advances an integrated conceptual framework of social media strategies. Based on the empirical findings of a case study that revisits evolving digital and social media strategies of European DMOs this paper maps the dynamics...

  1. Media studies for scientists

    CERN Multimedia

    2002-01-01

    "Science, with its inherent uncertainties, can be hard to put across to the public. But blaming 'sloppy' journalism is too easy. If researchers are to make their points effectively, they should learn more about how the media work" (1 page).

  2. The News Media Industry

    National Research Council Canada - National Science Library

    Bartlett, Charlie

    2003-01-01

    American news media has two fundamental roles in our democracy: that of eyewitness, giving citizens critical information, and also as the watchdog, providing another arm of "checks and balances" within our governmental system...

  3. Soft magnetic properties of bulk amorphous Co-based samples

    International Nuclear Information System (INIS)

    Fuezer, J.; Bednarcik, J.; Kollar, P.

    2006-01-01

    Ball milling of melt-spun ribbons and subsequent compaction of the resulting powders in the supercooled liquid region were used to prepare disc shaped bulk amorphous Co-based samples. The several bulk samples have been prepared by hot compaction with subsequent heat treatment (500 deg C - 575 deg C). The influence of the consolidation temperature and follow-up heat treatment on the magnetic properties of bulk samples was investigated. The final heat treatment leads to decrease of the coercivity to the value between the 7.5 to 9 A/m (Authors)

  4. Onset of bulk pinning in BSCCO single crystals

    Science.gov (United States)

    van der Beek, C. J.; Indenbom, M. V.; Berseth, V.; Li, T. W.; Benoit, W.

    1996-11-01

    The long growth defects often found in Bi2Sr2CaCu2O8, “single” crystals effectively weaken the geometrical barrier and lower the field of first flux penetration. This means that the intrinsic (bulk) magnetic properties can be more easily accessed using magnetic measurements. Thus, the onset of strong bulk flux pinning in the sample bulk is determined to lie at T ≈ 40 K, indepedent of whether the field strength is above or below the field of the second peak in the magnetisation.

  5. Bulk local states and crosscaps in holographic CFT

    Energy Technology Data Exchange (ETDEWEB)

    Nakayama, Yu [Department of Physics, Rikkyo University,Toshima, Tokyo 175-8501 (Japan); Kavli Institute for the Physics and Mathematics of the Universe (WPI), University of Tokyo,Kashiwa, Chiba 277-8583 (Japan); Ooguri, Hirosi [Kavli Institute for the Physics and Mathematics of the Universe (WPI), University of Tokyo,Kashiwa, Chiba 277-8583 (Japan); Walter Burke Institute for Theoretical Physics, California Institute of Technology,Pasadena, CA 91125 (United States); Center for Mathematical Sciences and Applications andCenter for the Fundamental Laws of Nature, Harvard University,Cambridge, MA 02138 (United States)

    2016-10-17

    In a weakly coupled gravity theory in the anti-de Sitter space, local states in the bulk are linear superpositions of Ishibashi states for a crosscap in the dual conformal field theory. The superposition structure can be constrained either by the microscopic causality in the bulk gravity or the bootstrap condition in the boundary conformal field theory. We show, contrary to some expectation, that these two conditions are not compatible to each other in the weak gravity regime. We also present an evidence to show that bulk local states in three dimensions are not organized by the Virasoro symmetry.

  6. Solving wave propagation within finite-sized composite media with linear embedding via Green's operators

    NARCIS (Netherlands)

    Lancellotti, V.; Tijhuis, A.G.

    2012-01-01

    The calculation of electromagnetic (EM) fields and waves inside finite-sized structures comprised of different media can benefit from a diakoptics method such as linear embedding via Green's operators (LEGO). Unlike scattering problems, the excitation of EM waves within the bulk dielectric requires

  7. Communications and media services

    Science.gov (United States)

    Mcculla, James W.; Kukowski, James F.

    1990-01-01

    NASA's internal and external communication methods are reviewed. NASA information services for the media, for the public, and for employees are discussed. Consideration is given to electron information distribution, the NASA TV-audio system, the NASA broadcast news service, astronaut appearances, technology and information exhibits, speaker services, and NASA news reports for internal communications. Also, the NASA worldwide electronic mail network is described and trends for future NASA communications and media services are outlined.

  8. Drupal 7 media

    CERN Document Server

    Tal, Liran

    2013-01-01

    This is a practical, hands-on guide packed with examples that will help you build rich Drupal 7 media web applications.If you are a Drupal site builder and you wish to spice up your web applications with rich media content, then this book is for you. A basic understanding of HTML, JavaScript, and basic PHP module development in Drupal would be helpful, but is not necessary.

  9. Chernobyl and the media

    Energy Technology Data Exchange (ETDEWEB)

    Dibdin, T.

    The way the media reported the Chernobyl nuclear reactor accident was discussed at a day seminar in Birmingham in July. Contributors were from the Forsmark nuclear power station in Sweden where the disaster was first noticed, the International Atomic Energy Agency, the Russian film industry, French TV and SCRAM. Personal experiences and opinions of Chernobyl and the media were discussed. The approach in West Germany, France, Finland and the United Kingdom is compared.

  10. Chernobyl and the media

    International Nuclear Information System (INIS)

    Dibdin, T.

    1987-01-01

    The way the media reported the Chernobyl nuclear reactor accident was discussed at a day seminar in Birmingham in July. Contributors were from the Forsmark nuclear power station in Sweden where the disaster was first noticed, the International Atomic Energy Agency, the Russian film industry, French TV and SCRAM. Personal experiences and opinions of Chernobyl and the media were discussed. The approach in West Germany, France, Finland and the United Kingdom is compared. (UK)

  11. Digital Media Ethics

    DEFF Research Database (Denmark)

    Ess, Charles

    Provides a philosophical-ethical "toolkit" for analyzing central ethical issues evoked by our use of new media, including privacy, copyright, violent and sexual content online, and cross-cultural communication online.......Provides a philosophical-ethical "toolkit" for analyzing central ethical issues evoked by our use of new media, including privacy, copyright, violent and sexual content online, and cross-cultural communication online....

  12. Social Media Cocreation Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Larson, Mia

    2015-01-01

    This paper explores how social media becomes a part of integrated marketing communications of festival organizations. The purpose of this paper is to conceptualize the co-creation of festival experiences online by comparing managerial strategies and communicative patterns of three large....... Based on the empirical findings, we propose an analytical framework to improve our understanding of the management of social media communications, offering three distinct value co-creation strategies in a festival context....

  13. Percolation in Heterogeneous Media

    International Nuclear Information System (INIS)

    Vocka, Radim

    1999-01-01

    This work is a theoretical reflection on the problematic of the modeling of heterogeneous media, that is on the way of their simple representation conserving their characteristic features. Two particular problems are addressed in this thesis. Firstly, we study the transport in porous media, that is in a heterogeneous media which structure is quenched. A pore space is represented in a simple way - a pore is symbolized as a tube of a given length and a given diameter. The fact that the correlations in the distribution of pore sizes are taken into account by a construction of a hierarchical network makes possible the modeling of porous media with a porosity distributed over several length scales. The transport in the hierarchical network shows qualitatively different phenomena from those observed in simpler models. A comparison of numerical results with experimental data shows that the hierarchical network gives a good qualitative representation of the structure of real porous media. Secondly, we study a problem of the transport in a heterogeneous media which structure is evolving during the time. The models where the evolution of the structure is not influenced by the transport are studied in detail. These models present a phase transition of the same nature as that observed on the percolation networks. We propose a new theoretical description of this transition, and we express critical exponents describing the evolution of the conductivity as a function of fundamental exponents of percolation theory. (author) [fr

  14. Media, risk and science

    CERN Document Server

    Allan, Stuart

    2002-01-01

    How is science represented by the media? Who defines what counts as a risk, threat or hazard, and why? In what ways do media images of science shape public perceptions? What can cultural and media studies tell us about current scientific controversies? "Media, Risk and Science" is an exciting exploration into an array of important issues, providing a much needed framework for understanding key debates on how the media represent science and risk. In a highly effective way, Stuart Allan weaves together insights from multiple strands of research across diverse disciplines. Among the themes he examines are: the role of science in science fiction, such as "Star Trek"; the problem of 'pseudo-science' in "The X-Files"; and how science is displayed in science museums. Science journalism receives particular attention, with the processes by which science is made 'newsworthy' unravelled for careful scrutiny. The book also includes individual chapters devoted to how the media portray environmental risks, HIV-AIDS, food s...

  15. Interplay between bulk medium evolution and (D)GLV energy loss

    International Nuclear Information System (INIS)

    Molnar, Denes; Sun, Deke

    2014-01-01

    We study the consistency between high-p T nuclear suppression (R AA ) and elliptic flow (v 2 ) using Gyulassy–Levai–Vitev (GLV) energy loss or a simpler power-law dE/dL formula, for a variety of bulk evolution models. The results generally confirm our earlier work [1] that found suppressed elliptic flow for transversely expanding media. One exception is the set of hydrodynamic solutions used recently [2] by Betz and Gyulassy, which give significantly higher v 2 but unfortunately assume unrealistic bag-model equation of state. On the other hand, we show that covariant treatment of energy loss introduces an interplay between jet direction and hydrodynamic flow of the medium, which largely counteracts elliptic flow suppression caused by transverse expansion

  16. Observation of structural universality in disordered systems using bulk diffusion measurement

    Science.gov (United States)

    Papaioannou, Antonios; Novikov, Dmitry S.; Fieremans, Els; Boutis, Gregory S.

    2017-12-01

    We report on an experimental observation of classical diffusion distinguishing between structural universality classes of disordered systems in one dimension. Samples of hyperuniform and short-range disorder were designed, characterized by the statistics of the placement of micrometer-thin parallel permeable barriers, and the time-dependent diffusion coefficient was measured by NMR methods over three orders of magnitude in time. The relation between the structural exponent, characterizing disorder universality class, and the dynamical exponent of the diffusion coefficient is experimentally verified. The experimentally established relation between structure and transport exemplifies the hierarchical nature of structural complexity—dynamics are mainly determined by the universality class, whereas microscopic parameters affect the nonuniversal coefficients. These results open the way for noninvasive characterization of structural correlations in porous media, complex materials, and biological tissues via a bulk diffusion measurement.

  17. Spectrophotometric Methods for the Assay of Fluvoxamine Using Chromogenic Reagents

    Directory of Open Access Journals (Sweden)

    V. Annapurna

    2010-01-01

    Full Text Available Simple, accurate and reproducible UV-Visible spectrophotometric methods were established for the assay of FXA based on the oxidative coupling and condensation reactions. Condensation and coupling of the FXA with Ninhydrin-Ascorbic acid is proposed in method A. Method B includes complexation of FXA with cobalt thiocyanate. The ligating property of FXA with sodium nitro prusside is incorporated in method C. The optical characteristics such as Beers law limits, molar absorptivity and Sandell’s sensitivity for the methods (A-C are given. Regression analysis using the method of least squares was made to evaluate the slope(b, intercept(a and correlation coefficient (r and standard error of estimation (Se for each system. Determination of FXA in bulk form and in pharmaceutical formulations were also incorporated.

  18. Advertising media selection and planning

    NARCIS (Netherlands)

    Moorman, M.; Neijens, P.C.; Smit, E.G.; Belch, M.A.; Belch, G.E.

    2010-01-01

    Reach, frequency, and timing are key concepts in selecting TV, radio, newspapers, magazines, out-of-home, direct mail, Internet, and other media for advertising campaigns. We discuss these concepts and their role in media selection and media planning processes. We also describe media and audience

  19. Mixed-Media File Systems

    NARCIS (Netherlands)

    Bosch, H.G.P.

    1999-01-01

    This thesis addresses the problem of implementing mixed-media storage systems. In this work a mixed-media file system is defined to be a system that stores both conventional (best-effort) file data and real-time continuous-media data. Continuous-media data is usually bulky, and servers storing and

  20. Media preparation and bacteriological tools.

    Science.gov (United States)

    Elbing, Karen; Brent, Roger

    2002-08-01

    Recipes are provided in this unit for minimal liquid media, rich liquid media, solid media, top agar, and stab agar. Also included are descriptions and useful information about tools used with growth media such as inoculating loops, sterile toothpicks and spreaders.

  1. Can groundwater be successfully implemented as a bulk water ...

    African Journals Online (AJOL)

    that groundwater can be developed as a potential viable bulk-water supply source. This paper attempts .... fracturing, even when using conventional geophysical methods. Gneiss and/or ..... will start to be self-sufficient in about 2018 and 2019.

  2. Role of the antiferromagnetic bulk spins in exchange bias

    Energy Technology Data Exchange (ETDEWEB)

    Schuller, Ivan K. [Center for Advanced Nanoscience and Physics Department, University of California San Diego, La Jolla, CA 92093 (United States); Morales, Rafael, E-mail: rafael.morales@ehu.es [Department of Chemical-Physics & BCMaterials, University of the Basque Country UPV/EHU (Spain); IKERBASQUE, Basque Foundation for Science, 48011 Bilbao (Spain); Batlle, Xavier [Departament Física Fonamental and Institut de Nanociència i Nanotecnologia, Universitat de Barcelona, c/ Martí i Franqués s/n, 08028 Barcelona, Catalonia (Spain); Nowak, Ulrich [Department of Physics, University of Konstanz, 78464 Konstanz (Germany); Güntherodt, Gernot [Physics Institute (IIA), RWTH Aachen University, Campus RWTH-Melaten, 52074 Aachen (Germany)

    2016-10-15

    This “Critical Focused Issue” presents a brief review of experiments and models which describe the origin of exchange bias in epitaxial or textured ferromagnetic/antiferromagnetic bilayers. Evidence is presented which clearly indicates that inner, uncompensated, pinned moments in the bulk of the antiferromagnet (AFM) play a very important role in setting the magnitude of the exchange bias. A critical evaluation of the extensive literature in the field indicates that it is useful to think of this bulk, pinned uncompensated moments as a new type of a ferromagnet which has a low total moment, an ordering temperature given by the AFM Néel temperature, with parallel aligned moments randomly distributed on the regular AFM lattice. - Highlights: • We address the role of bulk antiferromagnetic spins in the exchange bias phenomenon. • Significant experiments on how bulk AFM spins determine exchange bias are highlighted. • We explain the model that accounts for experimental results.

  3. Bulk Nano-structured Materials for Turbomachinery Components, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I effort seeks to exploit some of the tremendous benefits that could be attained from a revolutionary new approach to grain refinement in bulk...

  4. Preparation of Nb thin films with bulk transition temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Peirce, L H [Florida State Univ., Tallahassee (USA). Dept. of Physics

    1984-08-01

    Thin films (1000-2000 A) of Nb were prepared with bulk transition temperatures (9.25 K) by evaporation from an electron gun. Necessary substrate temperatures, evaporation rates and H/sub 2/O pressures were determined.

  5. Role of the antiferromagnetic bulk spins in exchange bias

    International Nuclear Information System (INIS)

    Schuller, Ivan K.; Morales, Rafael; Batlle, Xavier; Nowak, Ulrich; Güntherodt, Gernot

    2016-01-01

    This “Critical Focused Issue” presents a brief review of experiments and models which describe the origin of exchange bias in epitaxial or textured ferromagnetic/antiferromagnetic bilayers. Evidence is presented which clearly indicates that inner, uncompensated, pinned moments in the bulk of the antiferromagnet (AFM) play a very important role in setting the magnitude of the exchange bias. A critical evaluation of the extensive literature in the field indicates that it is useful to think of this bulk, pinned uncompensated moments as a new type of a ferromagnet which has a low total moment, an ordering temperature given by the AFM Néel temperature, with parallel aligned moments randomly distributed on the regular AFM lattice. - Highlights: • We address the role of bulk antiferromagnetic spins in the exchange bias phenomenon. • Significant experiments on how bulk AFM spins determine exchange bias are highlighted. • We explain the model that accounts for experimental results.

  6. Pseudopotentials for calculating the bulk and surface properties of solids

    International Nuclear Information System (INIS)

    Cohen, M.L.

    1983-01-01

    A survey is presented describing research in condensed matter physics using pseudopotentials to calculate electronic, structural, and vibrational properties of solids. Semiconductors are emphasized, and both bulk and surface calculations are discussed. (author) [pt

  7. Bulk metallic glass for low noise fluxgate, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The team of Prime Photonics, Virginia Tech, and Utron Kinetics propose to demonstrate a method for fabrication of a bulk, amorphous, cobalt-rich material that...

  8. Bulk and edge spin transport in topological magnon insulators

    Science.gov (United States)

    Rückriegel, Andreas; Brataas, Arne; Duine, Rembert A.

    2018-02-01

    We investigate the spin transport properties of a topological magnon insulator, a magnetic insulator characterized by topologically nontrivial bulk magnon bands and protected magnon edge modes located in the bulk band gaps. Employing the Landau-Lifshitz-Gilbert phenomenology, we calculate the spin current driven through a normal metal |topological magnon insulator |normal metal heterostructure by a spin accumulation imbalance between the metals, with and without random lattice defects. We show that bulk and edge transport are characterized by different length scales. This results in a characteristic system size where the magnon transport crosses over from being bulk dominated for small systems to edge dominated for larger systems. These findings are generic and relevant for topological transport in systems of nonconserved bosons.

  9. Children's media policy.

    Science.gov (United States)

    Jordan, Amy B

    2008-01-01

    Amy Jordan addresses the need to balance the media industry's potentially important contributions to the healthy development of America's children against the consequences of excessive and age-inappropriate media exposure. Much of the philosophical tension regarding how much say the government should have about media content and delivery stems from the U.S. Constitution's First Amendment protection against government interference in free speech, including commercial speech. Courts, Jordan says, have repeatedly had to weigh the rights of commercial entities to say what they please against the need to protect vulnerable citizens such as children. This balancing act is complicated even further, she says, because many government regulations apply only to broadcast television and not to non-broadcast media such as the Internet or cable television, though Congress has addressed the need to protect children's privacy online. The need to protect both free speech and children has given rise to a fluid media policy mix of federal mandates and industry self-regulation. Jordan describes the role of the three branches of the federal government in formulating and implementing media policy. She also notes the jockeying for influence in policymaking by industry lobbies, child advocacy groups, and academic researchers. The media industry itself, says Jordan, is spurred to self-regulation when public disapproval grows severe enough to raise the possibility of new government action. Jordan surveys a range of government and industry actions, from legislatively required parental monitoring tools, such as the V-Chip blocking device on television sets, to the voluntary industry ratings systems governing television, movies, and video games, to voluntary social website disclosures to outright government bans, such as indecency and child privacy information collection. She considers the success of these efforts in limiting children's exposure to damaging content and in improving parents

  10. Radiosotopic assay and binder therefor

    International Nuclear Information System (INIS)

    Caston, J.D.; Kamen, B.A.

    1976-01-01

    A rapid and less costly radioisotopic assay for measuring the concentration of folate in blood serum is described. This procedure utilizes 3 H-pteroylmonoglutamate, unlabeled 5-methyltetrahydrofolic acid, and a partially purified folate binder, such as for example a folate binder extracted from hog kidney. The procedure involves radioisotopically relating the bound amounts of a labeled folate and a known folate at various concentrations of the known folate in a system containing a predetermined amount of the labeled folate, a predetermined amount of the binder factor for the folates, and a predetermined amount of defolated test serum. 16 claims, 8 drawing figures

  11. Concentration polarization, surface currents, and bulk advection in a microchannel

    DEFF Research Database (Denmark)

    Nielsen, Christoffer Peder; Bruus, Henrik

    2014-01-01

    . A remarkable outcome of the investigations is the discovery of strong couplings between bulk advection and the surface current; without a surface current, bulk advection is strongly suppressed. The numerical simulations are supplemented by analytical models valid in the long channel limit as well...... as in the limit of negligible surface charge. By including the effects of diffusion and advection in the diffuse part of the electric double layers, we extend a recently published analytical model of overlimiting current due to surface conduction....

  12. Bulk Extractor 1.4 User’s Manual

    Science.gov (United States)

    2013-08-01

    optimistically decompresses data in ZIP, GZIP, RAR, and Mi- crosoft’s Hibernation files. This has proven useful, for example, in recovering email...command line. Java 7 or above must be installed on the machine for the Bulk Extractor Viewer to run. Instructions on running bulk_extractor from the... Hibernation File Fragments (decompressed and processed, not carved) Subsection 4.6 winprefetch Windows Prefetch files, file fragments (processed

  13. Anisotropic cosmological models with bulk viscosity and particle ...

    Indian Academy of Sciences (India)

    4.1.3 Ideal gas. In the case of an ideal gas. = 0 and pc = 0. Then eq. (2) becomes. ˙η + 3ηH = 0. (69). Equation (69), on integration gives η = η1t. −3/n,. (70) where η1 is an integrating constant. Equation (69) is the expression for particle creation density. This model has only bulk viscosity and bulk viscous stress is obtained as.

  14. Factors that may compromise bulk water distribution reliability

    OpenAIRE

    2012-01-01

    D.Ing. This thesis considers water supply and divides the water supply environment into three categories; the macro water supply environment, the water supply scheme and the consumers. Each of the categories is briefly explored in terms of the factors that may influence it. Subsequently, some of the unique features of a bulk water distribution system are dealt with, as well as different approaches related to bulk water distribution system design and assessment. One of these approaches, the...

  15. Does boundary quantum mechanics imply quantum mechanics in the bulk?

    Science.gov (United States)

    Kabat, Daniel; Lifschytz, Gilad

    2018-03-01

    Perturbative bulk reconstruction in AdS/CFT starts by representing a free bulk field ϕ (0) as a smeared operator in the CFT. A series of 1 /N corrections must be added to ϕ (0) to represent an interacting bulk field ϕ. These corrections have been determined in the literature from several points of view. Here we develop a new perspective. We show that correlation functions involving ϕ (0) suffer from ambiguities due to analytic continuation. As a result ϕ (0) fails to be a well-defined linear operator in the CFT. This means bulk reconstruction can be understood as a procedure for building up well-defined operators in the CFT which thereby singles out the interacting field ϕ. We further propose that the difficulty with defining ϕ (0) as a linear operator can be re-interpreted as a breakdown of associativity. Presumably ϕ (0) can only be corrected to become an associative operator in perturbation theory. This suggests that quantum mechanics in the bulk is only valid in perturbation theory around a semiclassical bulk geometry.

  16. Bulk density calculations from prompt gamma ray yield

    International Nuclear Information System (INIS)

    Naqvi, A.A.; Nagadi, M.M.; Al-Amoudi, O.S.B.; Maslehuddin, M.

    2006-01-01

    Full text: The gamma ray yield from a Prompt Gamma ray Neutron Activation Analysis (PGNAA) setup is a linear function of element concentration and neutron flux in a the sample with constant bulk density. If the sample bulk density varies as well, then the element concentration and the neutron flux has a nonlinear correlation with the gamma ray yield [1]. The measurement of gamma ray yield non-linearity from samples and a standard can be used to estimate the bulk density of the samples. In this study the prompt gamma ray yield from Blast Furnace Slag, Fly Ash, Silica Fumes and Superpozz cements samples have been measured as a function of their calcium and silicon concentration using KFUPM accelerator-based PGNAA setup [2]. Due to different bulk densities of the blended cement samples, the measured gamma ray yields have nonlinear correlation with calcium and silicon concentration of the samples. The non-linearity in the yield was observed to increase with gamma rays energy and element concentration. The bulk densities of the cement samples were calculated from ratio of gamma ray yield from blended cement and that from a Portland cement standard. The calculated bulk densities have good agreement with the published data. The result of this study will be presented

  17. Materials processing and machine applications of bulk HTS

    Science.gov (United States)

    Miki, M.; Felder, B.; Tsuzuki, K.; Xu, Y.; Deng, Z.; Izumi, M.; Hayakawa, H.; Morita, M.; Teshima, H.

    2010-12-01

    We report a refrigeration system for rotating machines associated with the enhancement of the trapped magnetic flux of bulk high-temperature superconductor (HTS) field poles. A novel cryogenic system was designed and fabricated. It is composed of a low-loss rotary joint connecting the rotor and a closed-cycle thermosiphon under a GM cryocooler using a refrigerant. Condensed neon gas was adopted as a suitable cryogen for the operation of HTS rotating machines with field poles composed of RE-Ba-Cu-O family materials, where RE is a rare-earth metal. Regarding the materials processing of the bulks HTS, thanks to the addition of magnetic particles to GdBa2Cu3O7 - d (Gd123) bulk superconductors an increase of more than 20% in the trapped magnetic flux density was achieved at liquid nitrogen temperature. Field-pole Gd123 bulks up to 46 mm in diameter were synthesized with the addition of Fe-B alloy magnetic particles and assembled into the synchronous machine rotor to be tested. Successful cooling of the magnetized rotor field poles down to 35 K and low-output-power rotating operation was achieved up to 720 rpm in the test machine with eight field-pole bulks. The present results show a substantial basis for making a prototype system of rotating machinery of applied HTS bulks.

  18. Materials processing and machine applications of bulk HTS

    Energy Technology Data Exchange (ETDEWEB)

    Miki, M; Felder, B; Tsuzuki, K; Xu, Y; Deng, Z; Izumi, M [Department of Marine Electronics and Mechanical Engineering, Tokyo University of Marine Science and Technology, 2-1-6, Etchu-jima, Koto-ku, Tokyo 135-8533 (Japan); Hayakawa, H [Kitano Seiki Co. Ltd, 7-17-3, Chuo, Ohta-ku, Tokyo 143-0024 (Japan); Morita, M; Teshima, H, E-mail: d082025@kaiyodai.ac.j [Nippon Steel Co. Ltd, 20-1, Shintomi, Huttsu-shi, Chiba 293-8511 (Japan)

    2010-12-15

    We report a refrigeration system for rotating machines associated with the enhancement of the trapped magnetic flux of bulk high-temperature superconductor (HTS) field poles. A novel cryogenic system was designed and fabricated. It is composed of a low-loss rotary joint connecting the rotor and a closed-cycle thermosiphon under a GM cryocooler using a refrigerant. Condensed neon gas was adopted as a suitable cryogen for the operation of HTS rotating machines with field poles composed of RE-Ba-Cu-O family materials, where RE is a rare-earth metal. Regarding the materials processing of the bulks HTS, thanks to the addition of magnetic particles to GdBa{sub 2}Cu{sub 3}O{sub 7-d} (Gd123) bulk superconductors an increase of more than 20% in the trapped magnetic flux density was achieved at liquid nitrogen temperature. Field-pole Gd123 bulks up to 46 mm in diameter were synthesized with the addition of Fe-B alloy magnetic particles and assembled into the synchronous machine rotor to be tested. Successful cooling of the magnetized rotor field poles down to 35 K and low-output-power rotating operation was achieved up to 720 rpm in the test machine with eight field-pole bulks. The present results show a substantial basis for making a prototype system of rotating machinery of applied HTS bulks.

  19. DIGITALIZATION AND NEW MEDIA LANDSCAPE

    OpenAIRE

    Tadej Praprotnik

    2016-01-01

    The article presents the phenomena of new communication technologies. It exposes the role of social media (Web 2.0) and sketches some global trends within the field of new media. It further outlines basic characteristics of traditional mass communication and consumption of media products, and as a counter-part presents interactive nature of a new media and the phenomena of user-generated media contents. The main focus of the article is the process of digitalization and its influence on import...

  20. Haters Phenomena in Social Media

    OpenAIRE

    Pradipta, Angga; Lailiyah, S.Sos, M.I.Kom, Nuriyatul

    2016-01-01

    Social media is internet-basic media, functioned as interaction media room based on multimedia technology. And social media created some effects. One of the negative effects of social media is haters phenomena. Haters are a person who easily said dirty words, harass, and humiliate to others. This phenomena causes anxiety—especially in Indonesia, even the Government issued public policy and letter of regulation about this phenomena, through Paragraph 27 verse (3) IT Constitution, Paragraph 45 ...

  1. Antioxidants and the Comet assay.

    Science.gov (United States)

    Cemeli, Eduardo; Baumgartner, Adolf; Anderson, Diana

    2009-01-01

    It is widely accepted that antioxidants, either endogenous or from the diet, play a key role in preserving health. They are able to quench radical species generated in situations of oxidative stress, either triggered by pathologies or xenobiotics, and they protect the integrity of DNA from genotoxicants. Nevertheless, there are still many compounds with unclear or unidentified prooxidant/antioxidant activities. This is of concern since there is an increase in the number of compounds synthesized or extracted from vegetables to which humans might be exposed. Despite the well-established protective effects of fruit and vegetables, the antioxidant(s) responsible have not all been clearly identified. There might also be alternative mechanisms contributing to the protective effects for which a comprehensive description is lacking. In the last two decades, the Comet assay has been extensively used for the investigation of the effects of antioxidants and many reports can be found in the literature. The Comet assay, a relatively fast, simple, and sensitive technique for the analysis of DNA damage in all cell types, has been applied for the screening of chemicals, biomonitoring and intervention studies. In the present review, several of the most well-known antioxidants are considered. These include: catalase, superoxide dismutase, glutathione peroxidase, selenium, iron chelators, melatonin, melanin, vitamins (A, B, C and E), carotenes, flavonoids, isoflavones, tea polyphenols, wine polyphenols and synthetic antioxidants. Investigations showing beneficial as well as non-beneficial properties of the antioxidants selected, either at the in vitro, ex vivo or in vivo level are discussed.

  2. Rotor assembly and assay method

    Science.gov (United States)

    Burtis, C.A.; Johnson, W.F.; Walker, W.A.

    1993-09-07

    A rotor assembly for carrying out an assay includes a rotor body which is rotatable about an axis of rotation, and has a central chamber and first, second, third, fourth, fifth, and sixth chambers which are in communication with and radiate from the central chamber. The rotor assembly further includes a shuttle which is movable through the central chamber and insertable into any of the chambers, the shuttle including a reaction cup carrying an immobilized antigen or an antibody for transport among the chambers. A method for carrying out an assay using the rotor assembly includes moving the reaction cup among the six chambers by passing the cup through the central chamber between centrifugation steps in order to perform the steps of: separating plasma from blood cells, binding plasma antibody or antigen, washing, drying, binding enzyme conjugate, reacting with enzyme substrate and optically comparing the resulting reaction product with unreacted enzyme substrate solution. The movement of the reaction cup can be provided by attaching a magnet to the reaction cup and supplying a moving magnetic field to the rotor. 34 figures.

  3. Data transformation methods for multiplexed assays

    Science.gov (United States)

    Tammero, Lance F. Bentley; Dzenitis, John M; Hindson, Benjamin J

    2013-07-23

    Methods to improve the performance of an array assay are described. A correlation between fluorescence intensity-related parameters and negative control values of the assay is determined. The parameters are then adjusted as a function of the correlation. As a result, sensitivity of the assay is improved without changes in its specificity.

  4. Multicentre comparison of a diagnostic assay

    DEFF Research Database (Denmark)

    Waters, Patrick; Reindl, Markus; Saiz, Albert

    2016-01-01

    ) assays in neuromyelitis optica spectrum disorders (NMOSD). METHODS: Coded samples from patients with neuromyelitis optica (NMO) or NMOSD (101) and controls (92) were tested at 15 European diagnostic centres using 21 assays including live (n=3) or fixed cell-based assays (n=10), flow cytometry (n=4...

  5. Capillary Electrophoresis Analysis of Conventional Splicing Assays

    DEFF Research Database (Denmark)

    de Garibay, Gorka Ruiz; Acedo, Alberto; García-Casado, Zaida

    2014-01-01

    of these assays is often challenging. Here, we explore this issue by conducting splicing assays in 31 BRCA2 genetic variants. All variants were assessed by RT-PCR followed by capillary electrophoresis and direct sequencing. If assays did not produce clear-cut outputs (Class-2 or Class-5 according to analytical...

  6. Contemplative Media Studies

    Directory of Open Access Journals (Sweden)

    Kevin Healey

    2015-08-01

    Full Text Available The psychological and socio-economic implications of digital technologies call for scholarship that engages questions about the nature of human consciousness, the construction of the self and the ethics of technical development. In this article, I outline a framework for an approach called contemplative media studies. This approach incorporates several different scholarly threads, namely: via critical political-economic media scholarship, a focus on achieving social and economic justice through policy initiatives and structural reform; via media and religious scholarship, an interest in the religious dimensions of digital culture and the role of media in shaping religious identity; and via contemplative studies, an appreciation of the applicability of contemplative principles to research methods and theory. This framework allows us to examine the spiritual ideology that drives the construction of commercial digital platforms and to ask whether alternative platforms might better catalyze human development. Anchored in a critical commitment to socio-economic justice, contemplative media studies is aimed at articulating an ethically-responsive and economically-sustainable architecture of human flourishing.

  7. Development of a surrogate angiogenic potency assay for clinical-grade stem cell production.

    Science.gov (United States)

    Lehman, Nicholas; Cutrone, Rochelle; Raber, Amy; Perry, Robert; Van't Hof, Wouter; Deans, Robert; Ting, Anthony E; Woda, Juliana

    2012-09-01

    Clinical results from acute myocardial infarction (AMI) patients treated with MultiStem®, a large-scale expanded adherent multipotent progenitor cell population (MAPC), have demonstrated a strong safety and benefit profile for these cells. The mechanism of benefit with MAPC treatment is a result, in part, of its ability to induce neovascularization through trophic support. Production of clinical-grade stem cell products requires the development of lot-release criteria based on potency assays that directly reflect the fundamental mechanistic pathway underlying the therapeutic response to verify manufacturing process consistency and product potency. Using an in vitro endothelial tube formation assay, a potency assay has been developed that reflects MAPC pro-angiogenic activity. Serum-free conditioned media collected from MAPC culture induced endothelial tube formation. A proteomic survey of angiogenic factors produced by the cells in vitro revealed candidate factors linked to angiogenic potency. Three cytokines, chemokine (C-X-C motif) ligand 5 (CXCL5), interleukin 8 (IL-8) and vascular endothelial growth factor (VEGF), were required for this angiogenic activity. Depletion of any of these factors from the media prevented tube formation, while adding back increasing amounts of these cytokines into the depleted serum-free conditioned media established the lower limits of each of the cytokines required to induce angiogenesis. A necessary threshold of angiogenic factor expression was established using an in vitro angiogenesis assay. By correlating the levels of the cytokines required to induce tube formation in vitro with levels of the factors found in the spent media from manufacturing production runs, detection of these factors was identified as a surrogate potency assay with defined pass/fail criteria.

  8. Cytotoxic effects of nanosilver are highly dependent on the chloride concentration and the presence of organic compounds in the cell culture media.

    Science.gov (United States)

    Kaiser, Jean-Pierre; Roesslein, Matthias; Diener, Liliane; Wichser, Adrian; Nowack, Bernd; Wick, Peter

    2017-01-06

    Nanosilver shows great promise for use in industrial, consumer or medical products because of its antimicrobial properties. However, the underlying mechanisms of the effects of silver nanoparticles on human cells are still controversial. Therefore, in the present study the influence of the chloride concentration and different serum content of culture media on the cytotoxic effects of nanosilver was systematically evaluated. Our results show that nanosilver toxicity was strongly affected by the composition of the culture media. The chloride concentration, as well as the carbon content affected the silver agglomeration and the complex formation. But also the dissolution of nanosilver and the availability of free silver ions (Ag + ) were severely affected by the compositions of the culture media. Cells, only exposed to silver particles in suspension and dissolved silver complexes, did not show any effects under all conditions. Nanosilver agglomerates and silver complexes were not very soluble. Thus, cells growing on the bottom of the culture dishes were exposed to sedimented nanosilver agglomerates and precipitated silver complexes. Locally, the concentration of silver on the cell surface was very high, much higher compared the silver concentration in the bulk solution. The cytotoxic effects of nanosilver are therefore a combination of precipitated silver complexes and organic silver compounds rather than free silver ions. Silver coatings are used in health care products due to their bacteriostatic or antibacterial properties. The assessment of the toxicity of a certain compound is mostly done using in vitro assays. Therefore, cytotoxicity studies of nanosilver using human cell cultures have to be undertaken under well controlled and understood cultivations conditions in order to improve the compatibility of different studies. Especially when eukaryotic versus prokaryotic systems are compared for the evaluation of the use of nanosilver as antibacterial coatings for

  9. Reconstructing random media

    International Nuclear Information System (INIS)

    Yeong, C.L.; Torquato, S.

    1998-01-01

    We formulate a procedure to reconstruct the structure of general random heterogeneous media from limited morphological information by extending the methodology of Rintoul and Torquato [J. Colloid Interface Sci. 186, 467 (1997)] developed for dispersions. The procedure has the advantages that it is simple to implement and generally applicable to multidimensional, multiphase, and anisotropic structures. Furthermore, an extremely useful feature is that it can incorporate any type and number of correlation functions in order to provide as much morphological information as is necessary for accurate reconstruction. We consider a variety of one- and two-dimensional reconstructions, including periodic and random arrays of rods, various distribution of disks, Debye random media, and a Fontainebleau sandstone sample. We also use our algorithm to construct heterogeneous media from specified hypothetical correlation functions, including an exponentially damped, oscillating function as well as physically unrealizable ones. copyright 1998 The American Physical Society

  10. Representative of the Media

    International Nuclear Information System (INIS)

    Domenech, F.

    2007-01-01

    Francesc Domenech recalled that the Vandellos-I accident created a very difficult situation for the nuclear industry. During the crisis the nuclear sector decided not to participate in any media activities. Finally, the industry realised that not being open only exacerbated the credibility crisis. The closure of the Vandellos -I power plant decreased the stress and offered an opportunity for the nuclear sector to change its attitude and public relations. In Mr. Domenech's view the Vandellos-I decommissioning project is a technical challenge undertaken by society. ENRESA made great efforts to rebuild mutual trust between the nuclear industry and the media. For the first time, journalists were provided with fluid data, some of them very complex, which the media had to render more understandable for the public. Finally, Mr. Domenech observed that nowadays it is the regulator which most needs to gain credibility. (author)

  11. Foams in porous media

    Energy Technology Data Exchange (ETDEWEB)

    Marsden, S.S.

    1986-07-01

    In 1978 a literature search on selective blocking of fluid flow in porous media was done by Professor S.S. Marsden and two of his graduate students, Tom Elson and Kern Huppy. This was presented as SUPRI Report No. TR-3 entitled ''Literature Preview of the Selected Blockage of Fluids in Thermal Recovery Projects.'' Since then a lot of research on foam in porous media has been done on the SUPRI project and a great deal of new information has appeared in the literature. Therefore we believed that a new, up-to-date search should be done on foam alone, one which would be helpful to our students and perhaps of interest to others. This is a chronological survey showing the development of foam flow, blockage and use in porous media, starting with laboratory studies and eventually getting into field tests and demonstrations. It is arbitrarily divided into five-year time periods. 81 refs.

  12. Subsidizing Media Innovation

    DEFF Research Database (Denmark)

    Kammer, Aske; Hobel, Emil

    When the Danish Parliament revised the media-subsidy framework in 2013/2014, one of the new initiatives was the introduction of a pool of funding earmarked to establishing and developing new news media – the so-called “innovation fund”. So, as the news industry struggles to keep journalism a viable...... and economically sustainable activity, the institutionalization of financial support for media innovation constitute one way for policy makers to bring (parts of) the journalistic environment up-to-date with the digital age, thereby improving the conditions for an informed citizenry in the future (Kammer...... scrutinizes the practical administration of the innovation fund in the first two years of its existence, analyzing all applications for innovation subsidies in 2014 and 2015 as well as all acceptance and rejection letters. With this empirical material and a combination of quantitative and qualitative...

  13. Media and metamedia management

    CERN Document Server

    Araújo, Xosé; Fernández, Valentín; García, Xosé

    2017-01-01

    Media and Metamedia Management has contributions from seven prestigious experts, who offer their expertise and the view from their vantage point on communication, journalism, advertising, audiovisual, and corporate, political, and digital communication, paying special attention to the role of new technologies, the Internet and social networks, also from an ethics and legal dimension. A total of 118 authors belonging to 31 universities from Spain, Portugal, England and Ecuador have contributed to this book edited, coordinated and introduced by professors Francisco Campos-Freire and Xosé López-García, from the University of Santiago de Compostela, José Rúas-Araújo, from the University of Vigo, and Valentín A. Martínez-Fernández, from the University of A Coruña. Readers may also enjoy 66 articles, grouped into diverse chapters, on Journalism and cyberjournalism, audiovisual sector and media economy, corporate and institutional communication, and new media and metamedia.

  14. Media and Multiplicity

    DEFF Research Database (Denmark)

    Blaagaard, Bolette

    2010-01-01

    In the past few years continental Europe has experienced a resurgence of right-wing party politics, nationalism and xenophobia. In this nationalist revival the media and advanced communications technologies have played a significant role, as evidenced by the debates following cases...... such as the Danish cartoon controversy, and Dutch politician Geert Wilders’s film, Fitna. Simultaneously, however, the media is more diverse and rhizomatic than ever and offers potential for cosmopolitanism, transnational ethical relations as well as radical anti-racist and anti-fascist interventions. This article...... explores the tensions within the relation between journalistic practice and the construction of the idea of the nation and the multiplicity of media and cultures which inhabit the spheres of journalism and nation....

  15. Enterprise Social Media

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2018-01-01

    This article reports an ethnographic research on effect of enterprise social media on communication of members in entrepreneurial teams. The researcher acted as an entrepreneur and as a team member in two entrepreneurial projects to observe the communication of team members within the enterprise...... social media. In addition to observation, he conducted some interviews with team members to collect supplementary data. A theoretical framework developed from an array of three metaphors: leaky pipe, echo chamber and social lubricant, and four organizational learning processes: social capital, boundary...... work, attention allocation and social analytics. By the interpretation of the collected data, a new metaphor of “living room” was proposed. This metaphor suggests that enterprise social media provide a space for interaction of internal-external people similar to what home members and guests do...

  16. Media for Reflection

    DEFF Research Database (Denmark)

    Knudsen, Morten

    2016-01-01

    This article develops the concept media for reflection in the interest of conceptualizing the interpretative frames that enable and limit reflection in management and leadership education. The concept ‘media for reflection’ allows us to conceptualize the social and cultural mediation of reflection...... without reducing reflection to an effect of the social structures and cultural norms in which it is embedded. Based on the developed theoretical framework, this article analyses how a renaissance ‘mirror for princes’ and contemporary research-based management education mediate reflection. The content...... of the mediations is analysed as well as the societal and organizational background. Furthermore, the means by which the two media enable and limit reflection in different ways is compared. Finally, the article discusses possible implications of the analysis in terms of management and leadership education....

  17. Boiling in porous media

    International Nuclear Information System (INIS)

    1998-01-01

    This conference day of the French society of thermal engineers was devoted to the analysis of heat transfers and fluid flows during boiling phenomena in porous media. This book of proceedings comprises 8 communications entitled: 'boiling in porous medium: effect of natural convection in the liquid zone'; 'numerical modeling of boiling in porous media using a 'dual-fluid' approach: asymmetrical characteristic of the phenomenon'; 'boiling during fluid flow in an induction heated porous column'; 'cooling of corium fragment beds during a severe accident. State of the art and the SILFIDE experimental project'; 'state of knowledge about the cooling of a particulates bed during a reactor accident'; 'mass transfer analysis inside a concrete slab during fire resistance tests'; 'heat transfers and boiling in porous media. Experimental analysis and modeling'; 'concrete in accidental situation - influence of boundary conditions (thermal, hydric) - case studies'. (J.S.)

  18. Media and (Demythologization

    Directory of Open Access Journals (Sweden)

    Damir Kukić

    2017-05-01

    Full Text Available The media participate in the creation of new myths in modern society. Some of these myths have been created in the entertainment industry as well as in celebrity culture. The new media stars, regardless of the period of their popularity, function as part of the star strategy. However, as an element of the cultural matrix, the media also participate in the process of creating new political myths. In ethno-national and closed societies the myths function as a fundamental component for the unification of a nation and the definition of its identity. In such a context, their role is to create an image of the world, by shaping images from the past, in which people from other cultures and nations are presented as enemies.

  19. Media Challenging Status Quo

    DEFF Research Database (Denmark)

    Sandvik, Kjetil

    and Libya creating headlines like “the Facebook revolution”. On the other hand, several scholars argue that it is naive to believe that social media in themselves create change: they may at the best facilitate already existing social and political movements (Downing 2008, Christakis & Fowler 2010...... and communication research is currently engaging in a longer and deeper process of examining and assessing the cultural consequences of networked communication. One present challenge is to understand digital media and networked communication at the intersection of established and countercultural, utopian......Digital media and especially so-called ‘social media’ have on the one hand been ascribed the power to change societies and empower democratic movements following the thoughts of e.g. Rheingold (2004), recently fueled by the democratic uprising in Arabic countries such as Egypt, Tunisia, Iran...

  20. Open Media Training Session

    CERN Multimedia

    CERN. Geneva; Marchant, Nadia

    2010-01-01

    Have you ever wondered how the media work and why some topics make it into the news and other don't? Would you like to know how to (and how not to) give an interview to a journalist? With the LHC preparing for first collisions at high energies, the world's media are again turning their attention to CERN. We're all likely to be called upon to explain what is happening at CERN to media, friends and neighbours. The seminar will be given by BBC television news journalists Liz Pike and Nadia Marchant, and will deal with the kind of questions we're likely to be confronted with through the restart period. Follow the webcast: http://webcast.cern.ch/