Sample records for bulk cargo

  1. 19 CFR 149.4 - Bulk and break bulk cargo. (United States)


    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Bulk and break bulk cargo. 149.4 Section 149.4... TREASURY (CONTINUED) IMPORTER SECURITY FILING § 149.4 Bulk and break bulk cargo. (a) Bulk cargo exempted.... (b) Break bulk cargo exempted from time requirement. For break bulk cargo that is exempt from the...

  2. Liquefaction Incidents of Mineral Cargoes on Board Bulk Carriers

    Directory of Open Access Journals (Sweden)

    Michael C. Munro


    Full Text Available Liquefaction is a frequently occurring problem taking place when transporting wet granular solid bulk cargoes on board bulk carriers. Liquefaction of a solid bulk cargo can occur when excessive dynamic loading, induced by rough seas and vessel vibrations, is transmitted to the cargo. From 1988 to 2015, there have been 24 suspected liquefaction incidents reported, which resulted in 164 casualties and the loss of 18 vessels. The objective of this study is to investigate the collective causes of liquefaction of solid bulk cargoes on board bulk carriers in order to make recommendations to prevent future incidents from occurring. This was achieved by analysing the seven available investigative reports relating to the incidents, focusing on the key findings and exploring the effect of excess moisture within the cargo. This study has placed significant emphasis on the importance of preventing ingress of water into the cargo during transportation, loading, and storage. Recommendations have been given, based on the key findings from the reports, to reduce the potential for liquefaction incidents to occur.

  3. Simulation for assessment of bulk cargo berths number (United States)

    Kuznetsov, A. L.; Kirichenko, A. V.; Slitsan, A. E.


    The world trade volumes of mineral resources have been growing constantly for decades, notwithstanding any economical crises. At the same time, the proximity of the bulk materials as products to the starting point of the integrated value added or logistic supply chain makes their unit price relatively low. This fact automatically causes a strong economic sensitivity of the supply chain to the level of operational expenses in every link. The core of the integrated logistic supply chain is its maritime segment, with the fleet and terminals (i.e. the cargo transportation system) serving as the base platform for it. In its turn, the terminal berths play a role of the interface between the fleet and the land-transportation sub-system. Current development of the maritime transportation technologies, ships and terminal specialization, vessel size growth, rationalization of route patterns, regionalization of trade etc., has made conventional calculation methods inadequate. The solution of the problem is in using object oriented simulation. At the same time, this approch usually assumes only ad hoc models. Thus, it does not provide the generality of its conventional analytical predecessors. The time and labor consumpting procedure of simulation results in a very narrow application domain of the model. This article describes a new simulation instrument, combining the generality of the analytical technoques with the efficiency of the object-oriented simulation. The approach implemented as a software module, which validity and adequacy are proved. The software was tested on several sea terminal design projects and confirmed its efficiency.

  4. The Design of Bulk Carrier Cargo Holds State Integrated Monitoring System

    Directory of Open Access Journals (Sweden)

    Gao Ru-jiang


    Full Text Available Most ship cargo hold Internal uses artificial watch or is unattended. Therefore, it is impossible to know the appropriate information of the cargo holds Internal timely and accurately. Cargo damage and ship accidents occurred frequently. Automation remote processing and monitoring alarm system for the bulk carrier is an important part of the marine automation. The system plays a significant role to guarantee the navigation safety for bulk carriers. The paper introduced the important parts of the integrated monitoring system, structural design, hardware configuration, various modules communication transmission and various data processing software design were included. Based on embedded development, the real time information including the cargo hold internal humidity temperature, oxygen concentration, smoke gas concentration, cold water well level and other data were collected, as well the hatch closed state was detected and the cargo hold internal real time video information was collected. Then the real-time communication between the control display and acquisition modules were assured. By adjusting the corresponding buttons on the bridge according to the monitoring information, so that the cargo hold always in a safe environment, so as to avoid cargo hold accidents.

  5. 75 FR 64585 - Bulk Solid Hazardous Materials: Harmonization With the International Maritime Solid Bulk Cargoes... (United States)


    ... Chapter VI of SOLAS requires that the master receive written cargo information, that the vessel carry... nonsubstantive changes, however, to correct grammar, internal paragraph references, and a temperature conversion... must-- (1) Be in writing...


    Directory of Open Access Journals (Sweden)

    M. M. Biliaiev


    Full Text Available Purpose. The scientific work is concentrated on development of 3D, 2D numerical models for the prediction of atmospheric pollution during transport of bulk cargo in the railway car. Methodology. To solve this problem numerical models were developed, based on the use of the motion equations of inviscid incompressible fluid and mass transfer, to determine the field of wind velocity near the cars and dispersion of dust in the atmosphere. For the numerical integration of the pollutant transport equation implicit alternating-triangular difference scheme was used. When constructing a difference scheme splitting of the transport equation is carried out that allows us to construct an efficient algorithm for solving a differential problem. Unknown value of the pollutant concentration at every step of splitting is determined by the explicit scheme – the method of point-to-point computation, which provides a simple numerical implementation of splitting equations. For numerical integration of the 3D equation for the velocity potential method of Richardson is applied. For numerical integration of the 2D equation for the velocity potential the method of total approximation is applied. The developed numerical models are the basis of established software package. On the basis of the constructed numerical models a computational experiment to assess the level of air pollution when demolition of coal dust from the gondola car was carried out. Findings. 3D, 2D numerical models that belong to the class «diagnostic models» were developed. These models take into account the main physical factors affecting the process of dust pollution dispersion in the atmosphere during transportation of bulk cargo, but require small costs of the computer time in the practice at the low and medium power machines. These models are used for serial calculations of various situations of scenarios related to issues of environmental protection and pollution intensity diagnostics for

  7. 75 FR 34573 - Bulk Solid Hazardous Materials: Harmonization With the International Maritime Solid Bulk Cargoes... (United States)


    ... IAEA International Atomic Energy Agency IMDG Code International Maritime Dangerous Goods Code IMO... authorized for bulk transportation by vessel and include special handling procedures based on the IMSBC Code... Management Facility (M-30), U.S. Department of Transportation, West Building Ground Floor, Room W12-140, 1200...

  8. Determination of Inertia Forces Acting on Break Bulk Cargo en Route

    Directory of Open Access Journals (Sweden)

    A.O. Chepok


    Full Text Available The paper presents the analytical method of defining inertia forces that act on break bulk cargo as a result of the oscillatory motion of the vessel exposed to the effect of ambient forces. Considering that the linear models of roll, pitch and heave applicable in this case, the problem is solved by expressing the angle of heel, the angle of pitch, and the amplitude of heave. The obtained functions are differentiated and the inertia forces are determined by means of applying the Newton's second law.

  9. Research on bulk-cargo-port berth assignment based on priority of resource allocation

    Directory of Open Access Journals (Sweden)

    Chunfang Guo


    Full Text Available Purpose: The purpose of this paper is to propose a Priority of Resource Allocation model about how to utilize the resources of the port efficiently, through the improvement of traditional ant colony algorithm, the ship-berth matching relation constraint matrix formed by ontology reasoning. Design/methodology/approach: Through questionnaires?Explore factor analysis (EFA and principal component analysis, the authors extract the importance of the goods, the importance of customers, and type of trade as the main factors of the ship operating priority. Then the authors combine berth assignment problem with the improved ant colony algorithm, and use the model to improve ship scheduling quality. Finally, the authors verify the model with physical data in a bulk-cargo-port in China. Findings: Test by the real data of bulk cargo port, it show that ships’ resource using priority and the length of waiting time are consistent; it indicates that the priority of resource allocation play a prominent role in improving ship scheduling quality. Research limitations: The questionnaires is limited in only one port group, more  related Influence factors should be considered to extend the conclusion. Practical implications: The Priority of Resource Allocation model in this paper can be used to improve the efficiency of the dynamic berth assignment. Originality: This paper makes the time of ship in port minimized as the optimization of key indicators and establishes a dynamic berth assignment model based on improved ant colony algorithm and the ontology reasoning model.

  10. Cargo Fire Hazards and Hazard Control for the Offshore Bulk Fuel Systems (OBFS). (United States)


    several inerting operations. The 7- 15 unit to cool and remove soot and particles. The cooled flue gas is then transferred to the cargo tanks through...a network of piping by a central blower . Typically, the central blower will be rated at a minimum of 125% of the total discharge capacity of the cargo...pumps. Since the inert gas must dis- place the amount of liquid being offloaded by the cargo pumps, the blower is rated in excess of the cargo

  11. 78 FR 54775 - Bulk Packaging To Allow for Transfer of Hazardous Liquid Cargoes (United States)


    ... International Bulk Chemical Code IM Intermodal IMDG Code International Maritime Dangerous Goods Code IMO... International Maritime Dangerous Goods Code (IMDG Code), section, which became effective in 2003. IMO... to provide greater flexibility in the selection and use of packaging in the transportation of...

  12. Cargo work for maritime operations

    Energy Technology Data Exchange (ETDEWEB)

    House, D.


    Previously published as Kemp & Young's Cargo Work, this new edition has been revised and expanded to reflect unit load containerised systems that are now used in the majority of cargo shipping, while retaining the necessary detail on transporting key classes of cargoes safely, efficiently and profitably. The book covers general principles and the latest international regulations that affect all cargo work, including cargo types and key characteristics of a wide range of cargo classes. It also details Roll On-Roll Off cargo handling, containerisation, equipment and offshore supply. Chapter 4 on bulk cargoes contains a section headed: Coal, characteristics, categories and procedures, precautions.

  13. 46 CFR 153.908 - Cargo viscosity and melting point information; measuring cargo temperature during discharge... (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo viscosity and melting point information; measuring cargo temperature during discharge: Categories A, B, and C. 153.908 Section 153.908 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS...

  14. 46 CFR 151.13-5 - Cargo segregation-tanks. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo segregation-tanks. 151.13-5 Section 151.13-5... CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Cargo Segregation § 151.13-5 Cargo segregation—tanks. (a... and list the various degrees of segregation required. Paragraphs and (2) of this section explain the...

  15. The Cargo

    DEFF Research Database (Denmark)

    Birch, Thomas; Charlton, Michael F.; Biggs, Lynn


    The Gresham ship was carrying a substantial cargo of different metals when she sank, representing a considerable financial loss. Reports record that some of that material recovered in 1846 included 2700 tin ingots, lead pigs and iron bars (British Archaeological Association, 1847, 361). The excav......The Gresham ship was carrying a substantial cargo of different metals when she sank, representing a considerable financial loss. Reports record that some of that material recovered in 1846 included 2700 tin ingots, lead pigs and iron bars (British Archaeological Association, 1847, 361......). The excavations in 2003–4 found a further three stamped lead ingots, five tin ingots and 42 iron bars from the hull area of the ship. The size of the original cargo remains unknown, though the estimated capacity of the ship, perhaps some 150 tons, provides an indication. In this chapter, the assemblage of lead...... not to be British, but from the Rhine area. Study of such a varied consignment presents an opportunity to learn more about trade in the late 16 th and early 17 th centuries, setting the cargo in a wider socio-economic context, and leads to suggestions as to a range of possible intended destinations of the vessel...

  16. 33 CFR 157.23 - Cargo and ballast system information. (United States)


    ... CARRYING OIL IN BULK Design, Equipment, and Installation § 157.23 Cargo and ballast system information. (a... automatic and manual operation of the cargo and ballast system in the vessel. (b) The format and information... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Cargo and ballast system...

  17. 46 CFR 153.440 - Cargo temperature sensors. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo temperature sensors. 153.440 Section 153.440 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS... Temperature Control Systems § 153.440 Cargo temperature sensors. (a) Except as prescribed in paragraph (c) of...

  18. 46 CFR 154.195 - Aluminum cargo tank: Steel enclosure. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Aluminum cargo tank: Steel enclosure. 154.195 Section 154.195 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Hull Structure § 154.195 Aluminum cargo tank: Steel enclosure. (a) An aluminum cargo tank and its...

  19. 46 CFR 151.25-2 - Cargo handling space. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  20. Wisconsin Air Cargo Study (United States)


    Air cargo is a key economic lifeline for the communities that have airports. Manufacturers, businesses, hospitals and : other community cornerstone employers depend on air cargo to successfully operate. While there is no doubt that air : cargo repres...

  1. 46 CFR 153.438 - Cargo pressure or temperature alarms required. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pressure or temperature alarms required. 153.438... CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Temperature Control Systems § 153.438 Cargo pressure or temperature alarms required. (a...

  2. 46 CFR 154.701 - Cargo pressure and temperature control: General. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pressure and temperature control: General. 154.701... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Cargo Pressure and Temperature Control § 154.701 Cargo pressure and temperature control: General...

  3. 46 CFR 153.370 - Minimum relief valve setting for ambient temperature cargo tanks. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Minimum relief valve setting for ambient temperature...) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS... temperature cargo tanks. The relief valve setting for a containment system that carries a cargo at ambient...

  4. 46 CFR 151.20-10 - Cargo system instrumentation. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo system instrumentation. 151.20-10 Section 151.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES... instrumentation. (a) Each tank operated at other than ambient temperature shall be provided with at least one...

  5. Air Cargo Marketing Development (United States)

    Kersey, J. W.


    The factors involved in developing a market for air cargo services are discussed. A comparison is made between the passenger traffic problems and those of cargo traffic. Emphasis is placed on distribution analyses which isolates total distribution cost, including logistical costs such as transportation, inventory, materials handling, packaging, and processing. Specific examples of methods for reducing air cargo costs are presented.

  6. Safety evaluation for packaging transport of LSA-II liquids in MC-312 cargo tanks

    Energy Technology Data Exchange (ETDEWEB)

    Carlstrom, R.F.


    This safety evaluation for packaging authorizes the onsite transfer of bulk LSA-II radioactive liquids in the 222-S Laboratory Cargo Tank and Liquid Effluent Treatment Facility Cargo Tanks (which are U.S. Department of Transportation MC-312 specification cargo tanks) from their operating facilities to tank farm facilities.

  7. 46 CFR 153.336 - Special cargo pump or pumproom requirements. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Special cargo pump or pumproom requirements. 153.336 Section 153.336 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Equipment Cargo Pumprooms § 153.336 Special cargo pump or pumproom requirements. (a) When Table 1 refers to...

  8. Multipurpose Cargo Transfer Bag (United States)

    Broyan, James; Baccus, Shelley


    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) program is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag, the suitcase-shaped common logistics carrying bag for Shuttle and the International Space Station. After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unzipped, unsnapped, and unfolded to be reused. Reuse ideas that have been investigated include partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing.

  9. Groupage Cargo Transportation Model

    Directory of Open Access Journals (Sweden)

    Aleksejevs Ruslans


    Full Text Available In this work we consider a specific problem of optimal planning of maritime transportation of multiproduct cargo by ships of one (corporate strategy or several (partially corporate strategy companies: the core of the problem consists of the existence of the network of intermediate seaports (i.e. transitional seaports, where for every ship arrived the cargo handling is done, and which are situated between the starting and the finishing seaports. In this work, there are mathematical models built from scratch in the form of multicriteria optimization problem; then the goal attainment method of Gembicki is used for reducing the built models to a one-criterion problem of linear programming.

  10. Large Cargo Containers (United States)


    FS ( ’ ’ \\ F4 f 1 NOTE: Fx , F2, F3, F^ - 15 Long Tons Minimum for ANSI MH 5.1.1. Figure 6, Externally...the various modes. The containerized cargo may be palletized or in unit loads. Existing facili- ties permit the makeup and simulation of most...on ramp. Loading dock on railcar truck/tractor Rail train makeup Switch engine Railway Loading dock to Forklift, MHE Ramp truck Loading dock to

  11. Acoustic Multipurpose Cargo Transfer Bag (United States)

    Baccus, Shelley


    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) program is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) are designed to be the same external volume as a regular cargo transfer bag, the common logistics carrier for the International Space Station. After use as a cargo bag, the MCTB can be unzipped and unfolded to be reused. This Acoustic MCTBs transform into acoustic blankets after the initial logistics carrying objective is complete.

  12. 29 CFR 1918.84 - Bulling cargo. (United States)


    ... 29 Labor 7 2010-07-01 2010-07-01 false Bulling cargo. 1918.84 Section 1918.84 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.84 Bulling cargo. (a) Bulling cargo shall be done with the bull line led directly from the heel block. However, bulling may be done from the...

  13. Proteomic profiling of autophagosome cargo in Saccharomyces cerevisiae.

    Directory of Open Access Journals (Sweden)

    Kuninori Suzuki

    Full Text Available Macroautophagy (autophagy is a bulk protein-degradation system ubiquitously conserved in eukaryotic cells. During autophagy, cytoplasmic components are enclosed in a membrane compartment, called an autophagosome. The autophagosome fuses with the vacuole/lysosome and is degraded together with its cargo. Because autophagy is important for the maintenance of cellular homeostasis by degrading unwanted proteins and organelles, identification of autophagosome cargo proteins (i.e., the targets of autophagy will aid in understanding the physiological roles of autophagy. In this study, we developed a method for monitoring intact autophagosomes ex vivo by detecting the fluorescence of GFP-fused aminopeptidase I, the best-characterized selective cargo of autophagosomes in Saccharomyces cerevisiae. This method facilitated optimization of a biochemical procedure to fractionate autophagosomes. A combination of LC-MS/MS with subsequent statistical analyses revealed a list of autophagosome cargo proteins; some of these are selectively enclosed in autophagosomes and delivered to the vacuole in an Atg11-independent manner. The methods we describe will be useful for analyzing the mechanisms and physiological significance of Atg11-independent selective autophagy.

  14. Scientific opinion on the evaluation of substances as acceptable previous cargoes for edible fats and oils

    DEFF Research Database (Denmark)

    Petersen, Annette

    Shipping of edible fats and oils into Europe is permitted in bulk tanks, provided that the previous cargo is included in a positive list. The European Commission requested EFSA to evaluate the acceptability as previous cargoes for fats and oils the substances calcium lignosulphonate, methyl acetate......, ethyl tert-butyl ether (ETBE) and ammonium sulphate. The evaluation was based on the same criteria as those used for the evaluation of the substances currently on the list in the Annex to Commission Directive 96/3/EC as acceptable previous cargoes for edible fats and oils. Methyl acetate and ETBE meet...... the criteria for acceptability as previous cargoes. Due to uncertainties, mainly with regard to the composition and toxicity of the low molecular mass fraction, and the fact that the toxicological database is limited to the 40–65 grade and does not cover all grades of calcium lignosulphonate shipped...

  15. Safety evaluation for packaging 222-S laboratory cargo tank for onetime type B material shipment

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, P.M.


    The purpose of this Safety Evaluation for Packaging (SEP) is to evaluate and document the safety of the onetime shipment of bulk radioactive liquids in the 222-S Laboratory cargo tank (222-S cargo tank). The 222-S cargo tank is a US Department of Transportation (DOT) MC-312 specification (DOT 1989) cargo tank, vehicle registration number HO-64-04275, approved for low specific activity (LSA) shipments in accordance with the DOT Title 49, Code of Federal Regulations (CFR). In accordance with the US Department of Energy, Richland Operations Office (RL) Order 5480.1A, Chapter III (RL 1988), an equivalent degree of safety shall be provided for onsite shipments as would be afforded by the DOT shipping regulations for a radioactive material package. This document demonstrates that this packaging system meets the onsite transportation safety criteria for a onetime shipment of Type B contents.

  16. Systems Analysis and Structural Design of an Unpressurized Cargo Delivery Vehicle (United States)

    Wu, K. Chauncey; Cruz, Jonathan N.; Antol, Jeffrey; Sasamoto, Washito A.


    The International Space Station will require a continuous supply of replacement parts for ongoing maintenance and repair after the planned retirement of the Space Shuttle in 2010. These parts are existing line-replaceable items collectively called Orbital Replacement Units, and include heavy and oversized items such as Control Moment Gyroscopes and stowed radiator arrays originally intended for delivery aboard the Space Shuttle. Current resupply spacecraft have limited to no capability to deliver these external logistics. In support of NASA's Exploration Systems Architecture Study, a team at Langley Research Center designed an Unpressurized Cargo Delivery Vehicle to deliver bulk cargo to the Space Station. The Unpressurized Cargo Delivery Vehicle was required to deliver at least 13,200 lbs of cargo mounted on at least 18 Flight Releasable Attachment Mechanisms. The Crew Launch Vehicle design recommended in the Exploration Systems Architecture Study would be used to launch one annual resupply flight to the International Space Station. The baseline vehicle design developed here has a cargo capacity of 16,000 lbs mounted on up to 20 Flight Releasable Attachment Mechanisms. Major vehicle components are a 5.5m-diameter cargo module containing two detachable cargo pallets with the payload, a Service Module to provide propulsion and power, and an aerodynamic nose cone. To reduce cost and risk, the Service Module is identical to the one used for the Crew Exploration Vehicle design.

  17. Cargo-shell and cargo-cargo couplings govern the mechanics of artificially loaded virus-derived cages (United States)

    Llauró, Aida; Luque, Daniel; Edwards, Ethan; Trus, Benes L.; Avera, John; Reguera, David; Douglas, Trevor; Pablo, Pedro J. De; Castón, José R.


    Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabilization. Although it is possible to pack heterologous cargoes inside virus-derived shells, little is known about the physical determinants of these artificial nanocontainers' stability. Atomic force and three-dimensional cryo-electron microscopy provided mechanical and structural information about the physical mechanisms of viral cage stabilization beyond the mere presence/absence of cargos. We analyzed the effects of cargo-shell and cargo-cargo interactions on shell stability after encapsulating two types of proteinaceous payloads. While bound cargo to the inner capsid surface mechanically reinforced the capsid in a structural manner, unbound cargo diffusing freely within the shell cavity pressurized the cages up to ~30 atm due to steric effects. Strong cargo-cargo coupling reduces the resilience of these nanocompartments in ~20% when bound to the shell. Understanding the stability of artificially loaded nanocages will help to design more robust and durable molecular nanocontainers.Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabilization. Although it is possible to pack heterologous cargoes inside virus-derived shells, little is known about the physical determinants of these artificial nanocontainers' stability. Atomic force and three-dimensional cryo-electron microscopy provided mechanical and structural information about the physical mechanisms of viral cage stabilization beyond the mere presence/absence of cargos. We analyzed the effects of cargo-shell and cargo-cargo interactions on shell stability after encapsulating two

  18. Characterizing Density and Complexity of Imported Cargos

    Energy Technology Data Exchange (ETDEWEB)

    Birrer, Nathaniel [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, Charles [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, Steven [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, Harry [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    X-ray inspection systems are used to detect radiological and nuclear threats in imported cargo. In order to better understand performance of these systems, system imaging capabilities and the characteristics of imported cargo need to be determined. This project involved calculation of the modulation transfer function as a metric of system imaging performance and a study of the density and inhomogeneity of imported cargos, which have been shown to correlate with human analysts, threat detection performance.

  19. 46 CFR 64.89 - Cargo pump unit. (United States)


    ... 46 Shipping 2 2010-10-01 2010-10-01 false Cargo pump unit. 64.89 Section 64.89 Shipping COAST... HANDLING SYSTEMS Cargo Handling System § 64.89 Cargo pump unit. (a) A cargo pump unit that fills or...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  20. Unmanned Cargo Aircraft : From Anywhere to Everywhere

    NARCIS (Netherlands)

    Heerkens, Hans


    While unmanned aircraft have been in use for decades, their suitability for transporting cargo is only now slowly being recognised. The first prototypes of unmanned cargo aircraft (UCA) are currently being tested. There are two categories of UCA: short-distance aircraft for delivering packages and

  1. 46 CFR 28.885 - Cargo gear. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo gear. 28.885 Section 28.885 Shipping COAST GUARD... Aleutian Trade Act Vessels § 28.885 Cargo gear. (a) The safe working load (SWL) for the assembled gear... the load the gear is approved to lift, excluding the weight of the gear itself. (b) All wire rope...

  2. 33 CFR 155.225 - Internal cargo transfer capability. (United States)


    ... Vessel Equipment § 155.225 Internal cargo transfer capability. Oil tankers and offshore oil barges must... cargo block, unless the vessel's installed cargo piping system is capable of performing this function. ...

  3. Cargo-mix optimization in Liner Shipping

    DEFF Research Database (Denmark)

    Christensen, Jonas Mark; Pacino, Dario; Fonseca, Joao Filipe Paiva

    ’ utilization.The more containers a vessel carries the smaller is the resulting CO2 emissions per transported tonof cargo. This is what can be seen as a win-win situation. Better vessel utilization will result bothin cleaner transport and in better revenue margins for the shippers. Focus on vessel intake...... maximization is old news for liner shippers. Container vessels are deliveredwith a nominal capacity that ship owners know is only theoretical. Unless the cargo weightdistribution is perfect, the nominal intake cannot be reached. Stowage coordinators fight this battleeveryday. They are the planners of the cargo...... and have to find a load configuration (stowage plan)that both suits the current cargo to be loaded but also guarantees that the vessel can be utilizedto its maximum in future ports. The size of nowadays vessels is, however, making this work harderand harder (Pacino et al. (2011)). Moreover, the cargo...

  4. Safety of Cargo Aircraft Handling Procedure

    Directory of Open Access Journals (Sweden)

    Daniel Hlavatý


    Full Text Available The aim of this paper is to get acquainted with the ways how to improve the safety management system during cargo aircraft handling. The first chapter is dedicated to general information about air cargo transportation. This includes the history or types of cargo aircraft handling, but also the means of handling. The second part is focused on detailed description of cargo aircraft handling, including a description of activities that are performed before and after handling. The following part of this paper covers a theoretical interpretation of safety, safety indicators and legislative provisions related to the safety of cargo aircraft handling. The fourth part of this paper analyzes the fault trees of events which might occur during handling. The factors found by this analysis are compared with safety reports of FedEx. Based on the comparison, there is a proposal on how to improve the safety management in this transportation company.

  5. Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

    DEFF Research Database (Denmark)

    Kristensen, Mie; Birch, Ditlev; Mørck Nielsen, Hanne


    -penetrating peptides (CPPs) constitute a promising tool and have shown applications for peptide and protein delivery into cells as well as across various epithelia and the blood-brain barrier (BBB). CPP-mediated delivery of peptides and proteins may be pursued via covalent conjugation of the CPP to the cargo peptide...... or protein or via physical complexation obtained by simple bulk-mixing of the CPP with its cargo. Both approaches have their pros and cons, and which is the better choice likely relates to the physicochemical properties of the CPP and its cargo as well as the route of administration, the specific barrier...... are believed to involve both endocytosis and direct translocation, but are still widely investigated and discussed. The fact that multiple factors influence the mechanisms responsible for cellular CPP internalization and the lack of sensitive methods for detection of the CPP, and in some cases the cargo...

  6. 33 CFR Appendix A to Part 157 - Damage Assumptions, Hypothetical Outflows, and Cargo Tank Size and Arrangements (United States)


    ... Outflows, and Cargo Tank Size and Arrangements A Appendix A to Part 157 Navigation and Navigable Waters... MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Pt. 157, App. A Appendix A to Part 157... from tank vessels, three dimensions of the extent of damage of a parallelepiped on the side and bottom...

  7. Intraflagellar transport complex structure and cargo interactions. (United States)

    Bhogaraju, Sagar; Engel, Benjamin D; Lorentzen, Esben


    Intraflagellar transport (IFT) is required for the assembly and maintenance of cilia, as well as the proper function of ciliary motility and signaling. IFT is powered by molecular motors that move along the axonemal microtubules, carrying large complexes of IFT proteins that travel together as so-called trains. IFT complexes likely function as adaptors that mediate interactions between anterograde/retrograde motors and ciliary cargoes, facilitating cargo transport between the base and tip of the cilium. Here, we provide an up-to-date review of IFT complex structure and architecture, and discuss how interactions with cargoes and motors may be achieved.


    Directory of Open Access Journals (Sweden)

    Gennadiy Yun


    Full Text Available Abstract. Lack of system research done by domestic and foreign scientists in the field of optimal cargostraffic distribution problem in Air Cargo Terminal, proves necessity of investigation and optimization of thisprocess. Mathematical models and algorithms of optimal problem solving for air cargos distribution inwarehouses on the basis of established functional dependence between freight flow stowage in warehousesand transport vehicle loading (unloading processes are presented in the article.Keywords:algorithms, dimensions of air cargo terminal, effectiveness of loading-unloading processes,freight flow, models.

  9. 29 CFR 1918.53 - Cargo winches. (United States)


    ...) There shall be no load other than the fall and cargo hook assembly on the winch when changing gears on a... service. (j) Winches shall not be used when one or more control points, either hoisting or lowering, are...

  10. Design of heavy lift cargo aircraft (United States)

    National Aeronautics and Space Administration — This is the bird of the skies of the future. The heavy lift cargo aircraft which is currently being developed by me has twice the payload capacity of an Antonov...

  11. System for inspection of stacked cargo containers (United States)

    Derenzo, Stephen [Pinole, CA


    The present invention relates to a system for inspection of stacked cargo containers. One embodiment of the invention generally comprises a plurality of stacked cargo containers arranged in rows or tiers, each container having a top, a bottom a first side, a second side, a front end, and a back end; a plurality of spacers arranged in rows or tiers; one or more mobile inspection devices for inspecting the cargo containers, wherein the one or more inspection devices are removeably disposed within the spacers, the inspection means configured to move through the spacers to detect radiation within the containers. The invented system can also be configured to inspect the cargo containers for a variety of other potentially hazardous materials including but not limited to explosive and chemical threats.

  12. Military Airlift: The Joint Cargo Aircraft Program

    National Research Council Canada - National Science Library

    Knight, William


    Joint Cargo Aircraft (JCA) is a joint acquisition program between the Army and the Air Force designed to procure a commercial off-the-shelf aircraft, capable of meeting Army requirements for "direct support" to maneuver units...

  13. Military Airlift: The Joint Cargo Aircraft Program

    National Research Council Canada - National Science Library

    Hess, Allan


    Joint Cargo Aircraft (JCA) is a joint acquisition program between the Army and Air Force intended to procure a commercial off-the-shelf aircraft capable of meeting Army and Air Force requirements for intra-theater airlift...

  14. 78 FR 68784 - Cargo Securing Manuals (United States)


    ... Stowage and Securing (CSS Code),'' any container vessel, subject to SOLAS, whose keel is laid on or after.... In order to test this, we developed an estimate of lost or jettisoned cargo incidents that are...

  15. 46 CFR 154.412 - Cargo tank corrosion allowance. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank corrosion allowance. 154.412 Section 154.412... Containment Systems § 154.412 Cargo tank corrosion allowance. A cargo tank must be designed with a corrosion...) carries a cargo that corrodes the tank material. Note: Corrosion allowance for independent tank type C is...



    Mr. Nguyen Hai Quang*


    This study aims to determine the contribution of air cargo transport and air cargo services to Gross Domestic Product (GDP) in Vietnam. These are the two major areas that make up the value of logistics in the air transport sector. Through the development of methodology and data collection for the six years from 2011 to 2016, the analysis results show that the contribution of air cargo transport and air cargo services to GDP in Vietnam has increased on average is 10.78% per year, nearly double...

  17. A cargo-sorting DNA robot. (United States)

    Thubagere, Anupama J; Li, Wei; Johnson, Robert F; Chen, Zibo; Doroudi, Shayan; Lee, Yae Lim; Izatt, Gregory; Wittman, Sarah; Srinivas, Niranjan; Woods, Damien; Winfree, Erik; Qian, Lulu


    Two critical challenges in the design and synthesis of molecular robots are modularity and algorithm simplicity. We demonstrate three modular building blocks for a DNA robot that performs cargo sorting at the molecular level. A simple algorithm encoding recognition between cargos and their destinations allows for a simple robot design: a single-stranded DNA with one leg and two foot domains for walking, and one arm and one hand domain for picking up and dropping off cargos. The robot explores a two-dimensional testing ground on the surface of DNA origami, picks up multiple cargos of two types that are initially at unordered locations, and delivers them to specified destinations until all molecules are sorted into two distinct piles. The robot is designed to perform a random walk without any energy supply. Exploiting this feature, a single robot can repeatedly sort multiple cargos. Localization on DNA origami allows for distinct cargo-sorting tasks to take place simultaneously in one test tube or for multiple robots to collectively perform the same task. Copyright © 2017, American Association for the Advancement of Science.

  18. Specialization and Flexibility in Port Cargo Handling

    Directory of Open Access Journals (Sweden)

    Hakkı KİŞİ


    Full Text Available Cargo handling appears to be the fundamental function of ports. In this context, the question of type of equipment and capacity rate need to be tackled with respect to cargo handling principles. The purpose of this study is to discuss the types of equipment to be used in ports, relating the matter to costs and capacity. The question is studied with a basic economic theoretical approach. Various conditions like port location, size, resources, cargo traffic, ships, etc. are given parameters to dictate the type and specification of the cargo handling equipment. Besides, a simple approach in the context of cost capacity relation can be useful in deciding whether to use specialized or flexible equipment. Port equipment is sometimes expected to be flexible to handle various types of cargo as many as possible and sometimes to be specialized to handle one specific type of cargo. The cases that might be suitable for those alternatives are discussed from an economic point of view in this article. Consequently, effectiveness and efficiency criteria play important roles in determining the handling equipment in ports.

  19. Characterizing X-ray Attenuation of Containerized Cargo

    Energy Technology Data Exchange (ETDEWEB)

    Birrer, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wang, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    X-ray inspection systems can be used to detect radiological and nuclear threats in imported cargo. In order to better understand performance of these systems, the attenuation characteristics of imported cargo need to be determined. This project focused on developing image processing algorithms for segmenting cargo and using x-ray attenuation to quantify equivalent steel thickness to determine cargo density. These algorithms were applied to over 450 cargo radiographs. The results are summarized in this report.

  20. New bulk carrier regulations enter into force on 1 July 1999

    Energy Technology Data Exchange (ETDEWEB)



    A new chapter of the International Convention for the Safety of Life at Sea (SOLAS), 1974, on bulk carrier safety, enters into force on 1 July 1999. The new chapter XII to SOLAS, `Additional Safety Measures for Bulk Carriers` was adopted at a conference held in November 1997, which was the culmination of several years work at IMO intended to address the rising numbers of bulk carriers being lost at sea - often with complete loss of crew on board - during the early 1990s. The requirements cover survivability and structural requirements for dry bulk carries - which carry products such as iron ore, grains and coal - to prevent them from sinking if water enters the ship for any reason. Existing ships which do not comply with the appropriate requirements will have to be reinforced - or they may have to limit either the loading pattern of the cargoes they carry or move to carrying lighter cargoes, such as grain or timber. 2 figs.

  1. Bulk Nanostructured Materials (United States)

    Koch, C. C.; Langdon, T. G.; Lavernia, E. J.


    This paper will address three topics of importance to bulk nanostructured materials. Bulk nanostructured materials are defined as bulk solids with nanoscale or partly nanoscale microstructures. This category of nanostructured materials has historical roots going back many decades but has relatively recent focus due to new discoveries of unique properties of some nanoscale materials. Bulk nanostructured materials are prepared by a variety of severe plastic deformation methods, and these will be reviewed. Powder processing to prepare bulk nanostructured materials requires that the powders be consolidated by typical combinations of pressure and temperature, the latter leading to coarsening of the microstructure. The thermal stability of nanostructured materials will also be discussed. An example of bringing nanostructured materials to applications as structural materials will be described in terms of the cryomilling of powders and their consolidation.

  2. Uncertainty Quantification for Cargo Hold Fires

    CERN Document Server

    DeGennaro, Anthony M; Martinelli, Luigi; Rowley, Clarence W


    The purpose of this study is twofold -- first, to introduce the application of high-order discontinuous Galerkin methods to buoyancy-driven cargo hold fire simulations, second, to explore statistical variation in the fluid dynamics of a cargo hold fire given parameterized uncertainty in the fire source location and temperature. Cargo hold fires represent a class of problems that require highly-accurate computational methods to simulate faithfully. Hence, we use an in-house discontinuous Galerkin code to treat these flows. Cargo hold fires also exhibit a large amount of uncertainty with respect to the boundary conditions. Thus, the second aim of this paper is to quantify the resulting uncertainty in the flow, using tools from the uncertainty quantification community to ensure that our efforts require a minimal number of simulations. We expect that the results of this study will provide statistical insight into the effects of fire location and temperature on cargo fires, and also assist in the optimization of f...

  3. Optimization of the air cargo supply chain

    Directory of Open Access Journals (Sweden)

    María Pérez Bernal


    Full Text Available Purpose: This paper aims to evaluate and optimize the various operations within the air cargo chain. It pursues to improve the efficiency of the air cargo supply chain and to provide more information to the decision-makers to optimize their fields.Design/methodology/approach: The method used is a process simulation modelling software, WITNESS, which provides information to the decision-makers about the most relevant parameters subject to optimization. The input for the simulation is obtained from a qualitative analysis of the air cargo supply chain with the involved agents and from a study of the external trade by air mode, given that their behaviour depend on the location. The case study is focused on a particular location, the Case of Zaragoza Airport (Spain.Findings: This paper demonstrates that efficiency of the air cargo supply chain can increase by leveraging several parameters such as bottlenecks, resources or warehouses.Originality/value: It explores the use of a simulation modeling software originally intended for manufacturing processes and extended to support decision making processes in the area of air cargo.

  4. Motility states in bidirectional cargo transport

    CERN Document Server

    Klein, Sarah; Santen, Ludger


    Intracellular cargos which are transported by molecular motors move stochastically along cytoskeleton filaments. In particular for bidirectionally transported cargos it is an open question whether the characteristics of their motion can result from pure stochastic fluctuations or whether some coordination of the motors is needed. The results of a mean-field model of cargo-motors dynamics, which was proposed by M\\"uller et al.[1] suggest the existence of high motility states which would result from a stochastic tug-of-war. Here we analyze a non-mean field extension of their model, that takes explicitly the position of each motor into account. We find that high motility states then disappear. We consider also a mutual motor-motor activation, as an explicit mechanism of motor coordination. We show that the results of the mean-field model are recovered only in case of a strong motor-motor activation in the limit of a high number of motors.

  5. Characterizing Complexity of Containerized Cargo X-ray Images

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Guangxing [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, Harry [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, Steven [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, Charles [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Birrer, Nat [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    X-ray imaging can be used to inspect cargos imported into the United States. In order to better understand the performance of X-ray inspection systems, the X-ray characteristics (density, complexity) of cargo need to be quantified. In this project, an image complexity measure called integrated power spectral density (IPSD) was studied using both DNDO engineered cargos and stream-of-commerce (SOC) cargos. A joint distribution of cargo density and complexity was obtained. A support vector machine was used to classify the SOC cargos into four categories to estimate the relative fractions.

  6. Port Security: Container Cargo Control

    Directory of Open Access Journals (Sweden)

    Vladivoj Vlaković


    Full Text Available illicittrafficking of threat materials, especially explosives, chemicalsubstances and radioactive or nuclear material. The transportof the threat materials by using sea routes is an advantageto te"orists especially because of the possible use of ship containers.The container is the basis of world trade. It is assumed thatthe world total movement in containers is about 200 millionTEUs ("20-foot equivalent units" per year. The list of materialstransported by containers which should be subject to inspectionwith the aim of reducing the acts of te"orism includes explosives,narcotics, chemical weapons, hazardous chemicalsand radioactive materials.Of special interest is nuclear te"orism. The risk of nuclearte"orism carried out by sub-national groups should be considerednot only in the construction and/or use of nuclear device,but also in possible radioactive contamination of large urbanareas.The system of ship containers control is an essential componentof «smart border» concept. Modem personnel, parcel,vehicle and cargo inspection systems are non-invasive imagingtechniques based on the use of nuclear analytical techniques.The inspection systems use penetrating radiations: hard x-rays(300 keV or more or gamma-rays from radioactive sources(137Cs and 60Co with energies from 600 to 1300 keV that producea high resolution radiograph of the load. Unfortunately,this information is "non-specific" in that it gives no informationon the nature of objects that do not match_ the travel documentsand are not recognized by a visual analysis of the radiographicpicture. Moreover, there are regions of the containerwherex and gamma-ray systems are "blind" due to the high averageatomic number of the objects i"adiated that appear asblack spots in the radiographic image.The systems being developed are based on the use of fast, 14Me V, neutrons with detection of associated a-particle from nuclearreactionbywhichneutrons are produced (d+t>a+n.Jnsuch a way the possibility to

  7. 46 CFR 151.45-4 - Cargo-handling. (United States)


    ... for pumps on barges or dock, but in no case shall the cargo pass through or over the towing vessel. (i... chafing between the steel parts of the vessel and the deck cargo. (l) Deck construction must be adequate...

  8. 76 FR 51847 - Air Cargo Screening (United States)


    ... due to changes that had to be made to the Final Rule. Data from industry indicates that industry met... that TSA, not private industry through the CCSP, should conduct screening of cargo to be transported on... either federalization or airline- only screening would unduly crowd screening onto airport grounds...

  9. Marine cargo imports and forest pest introductions (United States)

    F.H. Koch


    A major pathway for the introduction of nonindigenous forest pests is accidental transport on cargo imported from overseas. Diseases may be brought into the United States via commercial trade of nursery stock or other live plant material, as has been suggested for Phytophthora ramorum, the pathogen that causes sudden oak death (Ivors and others 2006). Insects may...

  10. 77 FR 65006 - Air Cargo Advance Screening (ACAS) Pilot Program (United States)


    ... SECURITY U.S. Customs and Border Protection Air Cargo Advance Screening (ACAS) Pilot Program AGENCY: U.S... targeting could occur in the pre-loading air cargo environment, thus establishing the ACAS pilot. Since then... July 27, 2012, CBP published ``Air Cargo Advance Screening Pilot Frequently Asked Questions'' at http...

  11. 46 CFR 154.560 - Cargo hose: Prototype test. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose: Prototype test. 154.560 Section 154.560... Hose § 154.560 Cargo hose: Prototype test. (a) Each cargo hose must be of a type that passes a prototype test at a pressure of at least five times its maximum working pressure at or below the minimum...

  12. 46 CFR 154.408 - Cargo tank external pressure load. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank external pressure load. 154.408 Section 154... Equipment Cargo Containment Systems § 154.408 Cargo tank external pressure load. For the calculation required under § 154.406 (a)(2) and (b), the external pressure load must be the difference between the...

  13. 33 CFR 157.132 - Cargo tanks: Hydrocarbon vapor emissions. (United States)


    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Cargo tanks: Hydrocarbon vapor... § 157.132 Cargo tanks: Hydrocarbon vapor emissions. Each tank vessel having a COW system under § 157.10a... must have— (a) A means to discharge hydrocarbon vapors from each cargo tank that is ballasted to a...

  14. 48 CFR 52.228-9 - Cargo Insurance. (United States)


    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Cargo Insurance. 52.228-9... Insurance. As prescribed in 28.313(a), insert the following clause: Cargo Insurance (MAY 1999) (a) The..., cargo insurance of $_____ per vehicle to cover the value of property on each vehicle and of $_____ to...

  15. Health risks in international container and bulk cargo transport due to volatile toxic compounds

    DEFF Research Database (Denmark)

    Baur, Xaver; Budnik, Lygia T; Zhao, Zhiwei


    To ensure the preservation and quality of the goods, physical (i.e. radiation) or chemical pest control is needed. The dark side of such consents may bear health risks in international transport and production sharing. In fact, between 10% and 20% of all containers arriving European harbors were ...

  16. 77 FR 14327 - Bulk Packaging To Allow for Transfer of Hazardous Liquid Cargoes (United States)


    ... Container IM Intermodal IMDG International Maritime Dangerous Goods (code) IMO International Maritime... International Maritime Organization's (IMO) International Maritime Dangerous Goods Code \\1\\ (IMDG Code) for the...) Fax: 202-493-2251. (3) Mail: Docket Management Facility (M-30), U.S. Department of Transportation...

  17. Heat transport in bulk/nanoporous/bulk silicon devices

    Energy Technology Data Exchange (ETDEWEB)

    Criado-Sancho, M. [Departamento de Ciencias y Técnicas Físicoquimicas, Facultad de Ciencias, UNED, Senda del Rey 9, 20040 Madrid (Spain); Jou, D., E-mail: [Departament de Física, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia (Spain); Institut d' Estudis Catalans, Carme 47, 08001 Barcelona, Catalonia (Spain)


    We study heat transport in bulk/nanoporous/bulk silicon devices; we show that, despite bulk/nanoporous devices may act as thermal rectifiers, the non-linear aspects of their joint thermal conductance are not strong enough to lead to a negative differential thermal resistance, necessary to allow bulk/nanoporous/bulk Si devices to act as thermal transistors. Furthermore, we explicitly study the effective thermal conductivity of the mentioned devices for several temperatures, geometries, porosities, and pore size.

  18. "Understanding" cosmological bulk viscosity


    Zimdahl, Winfried


    A universe consisting of two interacting perfect fluids with the same 4-velocity is considered. A heuristic mean free time argument is used to show that the system as a whole cannot be perfect as well but neccessarily implies a nonvanishing bulk viscosity. A new formula for the latter is derived and compared with corresponding results of radiative hydrodynamics.

  19. Bulk chemicals from biomass

    NARCIS (Netherlands)

    Haveren, van J.; Scott, E.L.; Sanders, J.P.M.


    Given the current robust forces driving sustainable production, and available biomass conversion technologies, biomass-based routes are expected to make a significant impact on the production of bulk chemicals within 10 years, and a huge impact within 20-30 years. In the Port of Rotterdam there is a

  20. The Navy’s Cargo Transportation System (United States)


    FUNDING NUMBERS PROGRAM ELEMENT NO PROJECT NO TASK NO WORK UNIT ACCESSION NO 11 TITLE (Include Security Classification) THE NAVY’S CARGO...limitations removed and their access to larger and more efficient aircraft improved, business exploded. This area has been aggressively sought after by not only...when requesting airlift services for QUICKTRANS in order to increase competition. 2) Develop a formalized Navy Integrated Transportaion Svstem

  1. Diffusion or bulk flow

    DEFF Research Database (Denmark)

    Schulz, Alexander


    symplasmic pathway from mesophyll to sieve elements. Crucial for the driving force is the question where water enters the pre-phloem pathway. Surprisingly, the role of PD in water movement has not been addressed so far appropriately. Modeling of assimilate and water fluxes indicates that in symplasmic...... the concentration gradient or bulk flow along a pressure gradient. The driving force seems to depend on the mode of phloem loading. In a majority of plant species phloem loading is a thermodynamically active process, involving the activity of membrane transporters in the sieve-element companion cell complex. Since...... is currently matter of discussion, called passive symplasmic loading. Based on the limited material available, this review compares the different loading modes and suggests that diffusion is the driving force in apoplasmic loaders, while bulk flow plays an increasing role in plants having a continuous...

  2. Diffusion or bulk flow

    DEFF Research Database (Denmark)

    Schulz, Alexander


    is currently matter of discussion, called passive symplasmic loading. Based on the limited material available, this review compares the different loading modes and suggests that diffusion is the driving force in apoplasmic loaders, while bulk flow plays an increasing role in plants having a continuous...... the concentration gradient or bulk flow along a pressure gradient. The driving force seems to depend on the mode of phloem loading. In a majority of plant species phloem loading is a thermodynamically active process, involving the activity of membrane transporters in the sieve-element companion cell complex. Since...... assimilate movement includes an apoplasmic step, this mode is called apoplasmic loading. Well established is also the polymer-trap loading mode, where the phloem-transport sugars are raffinose-family oligomers in herbaceous plants. Also this mode depends on the investment of energy, here for sugar...

  3. Are Marine Accident Really Accident? Fallacy of Random Marine Accidents in Dry Cargo Fleet

    Directory of Open Access Journals (Sweden)

    Emrah Bulut


    Full Text Available The aim of this paper is to investigate the relation between marine casualty and dry bulk cargo freight rate according to the existence of spurious accident phenomenon in the dry cargo vessel accidents. According to the conventional expectation, the volume of marine accidents is a random process since it is accidently occurred and not a man-made outcome. Under this circumstance, it is expected that the volume of marine accidents should be statistically uncorrelated with the freight market rates and positively correlated with the fleet size. However, the existence statistics on dry cargo marine accidents indicate high level of negative correlation with freight markets (-0.95 for no. of vessels and -0.79 for the volume of accidents in dwt and also high level of negative correlation with the fleet size (-0.81 for the volume of accidents in dwt. The asymmetric interaction between the widely accepted facts and the statistical foundations is the main concern of this paper which is named the “Fallacy of Random Marine Accidents (FRMA”. The possible reasons of the FRMA phenomenon are considered to be based on the man-made marine accidents because of the financial collapse or as the well known term the credit default risk.

  4. Micromegas in a bulk

    CERN Document Server

    Giomataris, Ioanis; Andriamonje, Samuel A; Aune, S; Charpak, Georges; Colas, P; Giganon, Arnaud; Rebourgeard, P C; Salin, P; Rebourgeard, Ph.


    In this paper we present a novel way to manufacture the bulk Micromegas detector. A simple process based on the PCB (Printed Circuit Board) technology is employed to produce the entire sensitive detector. Such fabrication process could be extended to very large area detectors made by the industry. The low cost fabrication together with the robustness of the electrode materials will make it extremely attractive for several applications ranging from particle physics and astrophysics to medicine

  5. Micromegas in a bulk

    Energy Technology Data Exchange (ETDEWEB)

    Giomataris, I. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France)]. E-mail:; De Oliveira, R. [CERN, Geneva (Switzerland); Andriamonje, S. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Aune, S. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Charpak, G. [CERN, Geneva (Switzerland); Colas, P. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Fanourakis, G. [Institute of Nuclear Physcis, NCSR Demokritos, Aghia Paraskevi 15310 (Greece); Ferrer, E. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Giganon, A. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Rebourgeard, Ph. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France); Salin, P. [DAPNIA, CEA Saclay, F91191 Gif sur Yvette CEDEX (France)


    In this paper, we present a novel way to manufacture the bulk Micromegas detector. A simple process based on the Printed Circuit Board (PCB) technology is employed to produce the entire sensitive detector. Such a fabrication process could be extended to very large area detectors made by the industry. The low cost fabrication together with the robustness of the electrode materials will make it attractive for several applications ranging from particle physics and astrophysics to medicine.


    Directory of Open Access Journals (Sweden)

    A. M. Okorokov


    Full Text Available Purpose. Making the qualitative administrative decisions defining strategy and tactics of transport cargo complexes development, and also its subsystems, is possible only in the presence of flexible optimization model. This model has to consider multiparametricity and multicriteriality of the given task, uncertainty and vagueness of input information, and also to provide process automation of searching the best parameters of the given production facility. The purpose of the research is to develop procedures for the strategic management of complex with view of the most important factors and their stochastic nature, which will execute the improvement of technical equipment of TCC. Methodology. The problem of strategic management is based on solving the complex of issues of the optimal number of shunting locomotives, optimal processing capability of handling the front and rational capacity of warehouses. The problem is solved on the basis of the proposed optimality criterion – the specific set of profit per unit of capital assets of freight industry. The listed problems are solved using simulation modeling of the freight industry. Findings. The use of developed procedure allows one to improve the technical equipment of the freight stations and complexes. Originality. For the first time it was developed the procedure of strategic management of development. This procedure allows taking into account the probabilistic nature of demand for services of transport freight complexes and technological processes of client services on the complex stations. The proposed procedure can be applied during when planning the investments in the creation of transport freight complexes. Practical value. Use as a basic tool of simulation models of complex cargo operation allows estimating the effectiveness of the capital investments, the level of operating costs, as well as the quality of meeting the demands of potential customers in transportations at the stage of

  7. 46 CFR 154.411 - Cargo tank thermal loads. (United States)


    ... Containment Systems § 154.411 Cargo tank thermal loads. For the calculations required under § 154.406(a)(4... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank thermal loads. 154.411 Section 154.411... thermal loads for the cooling down periods of cargo tanks for design temperatures lower than −55 °C (−67...

  8. Column generation approaches to ship scheduling with flexible cargo sizes

    DEFF Research Database (Denmark)

    Brønmo, Geir; Nygreen, Bjørn; Lysgaard, Jens

    We present a Dantzig-Wolfe procedure for the ship scheduling problem with flexible cargo sizes. This problem is similar to the well-known pickup and delivery problem with time windows, but the cargo sizes are defined by an interval instead of a fixed value. We show that the introduction of flexible...... cargo sizes to the column generation framework is not straightforward, and we handle the flexible cargo sizes heuristically when solving the subproblems. This leads to convergence issues in the branch-and-price search tree, and the optimal solution cannot be guaranteed. Hence we have introduced a method...

  9. Column generation approaches to ship scheduling with flexible cargo sizes

    DEFF Research Database (Denmark)

    Brønmo, Geir; Nygreen, Bjørn; Lysgaard, Jens


    We present a Dantzig-Wolfe procedure for the ship scheduling problem with flexible cargo sizes. This problem is similar to the well-known pickup and delivery problem with time windows, but the cargo sizes are defined by intervals instead of by fixed values. The flexible cargo sizes have...... consequences for the times used in the ports because both the loading and unloading times depend on the cargo sizes. We found it computationally hard to find exact solutions to the subproblems, so our method does not guarantee to find the optimum over all solutions. To be able to say something about how good...

  10. Comparative International Air Cargo Solutions: The Pathway to a Resilient, Adaptable, Balanced and Sustainable Secure Global Air Cargo Supply Chain (United States)


    counterfeit merchandise smugglers, and remains the weakest link in the air cargo transportation chain. The TSA and CBP continue to seek administrative...been exploited by narcotics, human and counterfeit merchandise smugglers for centuries, remains the weakest link in the air cargo transportation chain...have on the economies and industry concurrently. In 2011, air cargo merchandise transportation accounted for an estimated $424,265 million in U.S

  11. 46 CFR 153.976 - Transfer of packaged cargo or ship's stores. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Transfer of packaged cargo or ship's stores. 153.976... Transfer Procedures § 153.976 Transfer of packaged cargo or ship's stores. The person in charge of cargo... cargo or ship's stores are transferred unless transfer of the packaged cargo or ship's stores does not...

  12. Bulk-Fill Resin Composites

    DEFF Research Database (Denmark)

    Benetti, Ana Raquel; Havndrup-Pedersen, Cæcilie; Honoré, Daniel


    the restorative procedure. The aim of this study, therefore, was to compare the depth of cure, polymerization contraction, and gap formation in bulk-fill resin composites with those of a conventional resin composite. To achieve this, the depth of cure was assessed in accordance with the International Organization...... for Standardization 4049 standard, and the polymerization contraction was determined using the bonded-disc method. The gap formation was measured at the dentin margin of Class II cavities. Five bulk-fill resin composites were investigated: two high-viscosity (Tetric EvoCeram Bulk Fill, SonicFill) and three low......-viscosity (x-tra base, Venus Bulk Fill, SDR) materials. Compared with the conventional resin composite, the high-viscosity bulk-fill materials exhibited only a small increase (but significant for Tetric EvoCeram Bulk Fill) in depth of cure and polymerization contraction, whereas the low-viscosity bulk...

  13. Creating bulk nanocrystalline metal.

    Energy Technology Data Exchange (ETDEWEB)

    Fredenburg, D. Anthony (Georgia Institute of Technology, Atlanta, GA); Saldana, Christopher J. (Purdue University, West Lafayette, IN); Gill, David D.; Hall, Aaron Christopher; Roemer, Timothy John (Ktech Corporation, Albuquerque, NM); Vogler, Tracy John; Yang, Pin


    Nanocrystalline and nanostructured materials offer unique microstructure-dependent properties that are superior to coarse-grained materials. These materials have been shown to have very high hardness, strength, and wear resistance. However, most current methods of producing nanostructured materials in weapons-relevant materials create powdered metal that must be consolidated into bulk form to be useful. Conventional consolidation methods are not appropriate due to the need to maintain the nanocrystalline structure. This research investigated new ways of creating nanocrystalline material, new methods of consolidating nanocrystalline material, and an analysis of these different methods of creation and consolidation to evaluate their applicability to mesoscale weapons applications where part features are often under 100 {micro}m wide and the material's microstructure must be very small to give homogeneous properties across the feature.

  14. 46 CFR 13.109 - Tankerman endorsement: Authorized cargoes. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Tankerman endorsement: Authorized cargoes. 13.109... CERTIFICATION OF TANKERMEN General § 13.109 Tankerman endorsement: Authorized cargoes. (a) Each tankerman endorsement described in § 13.107 will expressly limit the holder's service under it to transfers involving...

  15. A matheuristic for the Cargo Mix Problem with Block Stowage

    DEFF Research Database (Denmark)

    Christensen, Jonas Mark; Pacino, Dario


    The cargo-mix problem aims at selecting the amount of containers of a given type to load on a vessel. In this article we present an extended definition that includes the analysis of a circular route with draft restrictions, limitations on expected cargo and the use of a block stowage strategy...

  16. Basic mechanisms for recognition and transport of synaptic cargos

    NARCIS (Netherlands)

    M.A. Schlager (Max); C.C. Hoogenraad (Casper)


    textabstractSynaptic cargo trafficking is essential for synapse formation, function and plasticity. In order to transport synaptic cargo, such as synaptic vesicle precursors, mitochondria, neurotransmitter receptors and signaling proteins to their site of action, neurons make use of molecular motor

  17. 19 CFR 4.62 - Accounting for inward cargo. (United States)


    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Accounting for inward cargo. 4.62 Section 4.62 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Foreign Clearances § 4.62 Accounting for inward cargo...

  18. 49 CFR 1549.101 - Acceptance, screening, and transfer of cargo. (United States)


    ... that cargo in accordance with this part, or parts 1544, 1546, or 1548 of this chapter. (d) Chain of custody. Each certified cargo screening facility must protect the cargo from unauthorized access from the...

  19. Transporting "exceptional cargo" on the CERN sites

    CERN Multimedia

    EN Department


    When the Transport Service is managing "exceptional cargo", the driver and the escort are often in charge of an operation involving equipment worth many hundred thousand francs. Equipment that may well be irreplaceable for a facility or an experiment.   The members of the Transport Service who carry out these tasks are very professional and are – needless to say – highly concentrated on the job. They count on your understanding and support in the traffic on site. Their convoys are – for good reasons – moving slowly. Kindly do not overtake, do not cut in in front of them and do not drive too closely. Respect the escort and do not position yourself between the truck and the escort vehicles. The EN department counts on your courtesy on the road.  

  20. 49 CFR 1546.213 - Access to cargo: Security threat assessments for cargo personnel in the United States. (United States)


    ... Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY FOREIGN AIR CARRIER SECURITY Operations § 1546.213 Access to cargo... 49 Transportation 9 2010-10-01 2010-10-01 false Access to cargo: Security threat assessments for...

  1. 49 CFR 1548.15 - Access to cargo: Security threat assessments for individuals having unescorted access to cargo. (United States)


    ... Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY INDIRECT AIR CARRIER SECURITY § 1548.15 Access to cargo: Security threat... 49 Transportation 9 2010-10-01 2010-10-01 false Access to cargo: Security threat assessments for...

  2. Microfabricated Bulk Piezoelectric Transformers (United States)

    Barham, Oliver M.

    Piezoelectric voltage transformers (PTs) can be used to transform an input voltage into a different, required output voltage needed in electronic and electro- mechanical systems, among other varied uses. On the macro scale, they have been commercialized in electronics powering consumer laptop liquid crystal displays, and compete with an older, more prevalent technology, inductive electromagnetic volt- age transformers (EMTs). The present work investigates PTs on smaller size scales that are currently in the academic research sphere, with an eye towards applications including micro-robotics and other small-scale electronic and electromechanical sys- tems. PTs and EMTs are compared on the basis of power and energy density, with PTs trending towards higher values of power and energy density, comparatively, indicating their suitability for small-scale systems. Among PT topologies, bulk disc-type PTs, operating in their fundamental radial extension mode, and free-free beam PTs, operating in their fundamental length extensional mode, are good can- didates for microfabrication and are considered here. Analytical modeling based on the Extended Hamilton Method is used to predict device performance and integrate mechanical tethering as a boundary condition. This model differs from previous PT models in that the electric enthalpy is used to derive constituent equations of motion with Hamilton's Method, and therefore this approach is also more generally applica- ble to other piezoelectric systems outside of the present work. Prototype devices are microfabricated using a two mask process consisting of traditional photolithography combined with micropowder blasting, and are tested with various output electri- cal loads. 4mm diameter tethered disc PTs on the order of .002cm. 3 , two orders smaller than the bulk PT literature, had the followingperformance: a prototype with electrode area ratio (input area / output area) = 1 had peak gain of 2.3 (+/- 0.1), efficiency of 33 (+/- 0

  3. Developing bulk exchange spring magnets

    Energy Technology Data Exchange (ETDEWEB)

    Mccall, Scott K.; Kuntz, Joshua D.


    A method of making a bulk exchange spring magnet by providing a magnetically soft material, providing a hard magnetic material, and producing a composite of said magnetically soft material and said hard magnetic material to make the bulk exchange spring magnet. The step of producing a composite of magnetically soft material and hard magnetic material is accomplished by electrophoretic deposition of the magnetically soft material and the hard magnetic material to make the bulk exchange spring magnet.

  4. Structural basis of cargo recognitions for class V myosins. (United States)

    Wei, Zhiyi; Liu, Xiaotian; Yu, Cong; Zhang, Mingjie


    Class V myosins (MyoV), the most studied unconventional myosins, recognize numerous cargos mainly via the motor's globular tail domain (GTD). Little is known regarding how MyoV-GTD recognizes such a diverse array of cargos specifically. Here, we solved the crystal structures of MyoVa-GTD in its apo-form and in complex with two distinct cargos, melanophilin and Rab interacting lysosomal protein-like 2. The apo-MyoVa-GTD structure indicates that most mutations found in patients with Griscelli syndrome, microvillus inclusion disease, or cancers or in "dilute" rodents likely impair the folding of GTD. The MyoVa-GTD/cargo complex structure reveals two distinct cargo-binding surfaces, one primarily via charge-charge interaction and the other mainly via hydrophobic interactions. Structural and biochemical analysis reveal the specific cargo-binding specificities of various isoforms of mammalian MyoV as well as very different cargo recognition mechanisms of MyoV between yeast and higher eukaryotes. The MyoVa-GTD structures resolved here provide a framework for future functional studies of vertebrate class V myosins.

  5. Exploration of models for a cargo assembly planning problem


    Belov, G.; Boland, N.; Savelsbergh, M.W.P.; Stuckey, P. J.


    We consider a real-world cargo assembly planning problem arising in a coal supply chain. The cargoes are built on the stockyard at a port terminal from coal delivered by trains. Then the cargoes are loaded onto vessels. Only a limited number of arriving vessels is known in advance. The goal is to minimize the average delay time of the vessels over a long planning period. We model the problem in the MiniZinc constraint programming language and design a large neighbourhood search scheme. The ef...

  6. Neutron and Photon Transport in Sea-Going Cargo Containers

    Energy Technology Data Exchange (ETDEWEB)

    Pruet, J; Descalle, M; Hall, J; Pohl, B; Prussin, S G


    Factors affecting sensing of small quantities of fissionable material in large sea-going cargo containers by neutron interrogation and detection of {beta}-delayed photons are explored. The propagation of variable-energy neutrons in cargos, subsequent fission of hidden nuclear material and production of the {beta}-delayed photons, and the propagation of these photons to an external detector are considered explicitly. Detailed results of Monte Carlo simulations of these stages in representative cargos are presented. Analytical models are developed both as a basis for a quantitative understanding of the interrogation process and as a tool to allow ready extrapolation of the results to cases not specifically considered here.

  7. Design of a high capacity long range cargo aircraft (United States)

    Weisshaar, Terrence A.


    This report examines the design of a long range cargo transport to attempt to reduce ton-mile shipping costs and to stimulate the air cargo market. This design effort involves the usual issues but must also include consideration of: airport terminal facilities; cargo loading and unloading; and defeating the 'square-cube' law to design large structures. This report reviews the long range transport design problem and several solutions developed by senior student design teams at Purdue University. The results show that it will be difficult to build large transports unless the infrastructure is changed and unless the basic form of the airplane changes so that aerodynamic and structural efficiencies are employed.

  8. Air Cargo Transportation Route Choice Analysis (United States)

    Obashi, Hiroshi; Kim, Tae-Seung; Oum, Tae Hoon


    Using a unique feature of air cargo transshipment data in the Northeast Asian region, this paper identifies the critical factors that determine the transshipment route choice. Taking advantage of the variations in the transport characteristics in each origin-destination airports pair, the paper uses a discrete choice model to describe the transshipping route choice decision made by an agent (i.e., freight forwarder, consolidator, and large shipper). The analysis incorporates two major factors, monetary cost (such as line-haul cost and landing fee) and time cost (i.e., aircraft turnaround time, including loading and unloading time, custom clearance time, and expected scheduled delay), along with other controls. The estimation method considers the presence of unobserved attributes, and corrects for resulting endogeneity by use of appropriate instrumental variables. Estimation results find that transshipment volumes are more sensitive to time cost, and that the reduction in aircraft turnaround time by 1 hour would be worth the increase in airport charges by more than $1000. Simulation exercises measures the impacts of alternative policy scenarios for a Korean airport, which has recently declared their intention to be a future regional hub in the Northeast Asian region. The results suggest that reducing aircraft turnaround time at the airport be an effective strategy, rather than subsidizing to reduce airport charges.

  9. ATV Cargo Integration Safety Certification Process (United States)

    Garbellini, L.; Heimann, T. J.


    A large number of manned modules are being progressively launched to the International Space Station (ISS) and integrated on-orbit, required to be operated and maintained over long on-orbit stay time, supported by periodical servicing and supply.The European Space Agency (ESA), together with its several industrial aerospace contractors such as Alcatel Alenia Space, is deeply involved in development of space systems hardware, in planning and execution of mission operations, logistics and supply to ISS of consumables, payloads, scientific experiments, orbital replacement units up to station modules and infrastructures, as needed by the ISS utilization cycles. In this frame safety plays a significant role to assure that the safety of the systems is preserved throughout the ISS exploitation phase. This paper summarizes methods and requirements for the safety certification process being implemented to dry cargo integration and accommodation in Jules Verne, the 1st flight of the Automated Transfer Vehicle (ATV), one of the major ESA contributions to the utilization of ISS.

  10. Aggregating Secondary Source Data for Air Cargo Prescreening Project (United States)

    National Aeronautics and Space Administration — We propose to improve the effectiveness of air cargo prescreening by enabling background knowledge about companies and products to be used for threat assessment. The...

  11. Multi-Purpose Logistics Module (MPLM) Cargo Heat Exchanger (United States)

    Zampiceni, John J.; Harper, Lon T.


    This paper describes the New Shuttle Orbiter's Multi- Purpose Logistics Modulo (MPLM) Cargo Heat Exchanger (HX) and associated MPLM cooling system. This paper presents Heat Exchanger (HX) design and performance characteristics of the system.

  12. Cargo/Weapons Elevator Land Based Engineering Site (United States)

    Federal Laboratory Consortium — The Cargo and Weapons Facility consists of a suite of full scale and component test facilities contiguously located in building 77H. The site was constructed in 1987...

  13. Dust prevention in bulk material transportation and handling (United States)

    Kirichenko, A. V.; Kuznetsov, A. L.; Pogodin, V. A.


    The environmental problem of territory and atmosphere pollution caused by transportation and handling of dust-generating bulk cargo materials is quite common for the whole world. The reducing of weight of fine class coal caused by air blowing reaches the level of 0.5–0.6 t per railcar over the 500 km transportation distance, which is equal to the loss of 1 % of the total weight. The studies showed that all over the country in the process of the railroad transportation, the industry loses 3–5 metric tonnes of coal annually. There are several common tactical measurers to prevent dust formation: treating the dust-producing materials at dispatch point with special liquid solutions; watering the stacks and open handling points of materials; frequent dust removing and working area cleaning. Recently there appeared several new radical measures for pollution prevention in export of ore and coal materials via sea port terminals, specifically: wind-dust protection screens, the container cargo handling system of delivery materials to the hold of the vessels. The article focuses on the discussion of these measures.

  14. 19 CFR 122.117 - Requirements for transit air cargo transport. (United States)


    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Requirements for transit air cargo transport. 122... Requirements for transit air cargo transport. (a) Transportation—(1) Port to port. Transit air cargo may be... cargo, a receipt shall be given. The receipt shall be made by the airline responsible for transport or...

  15. 46 CFR 153.371 - Minimum relief valve setting for refrigerated cargo tanks. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Minimum relief valve setting for refrigerated cargo... Design and Equipment Cargo Venting Systems § 153.371 Minimum relief valve setting for refrigerated cargo tanks. The relief valve setting for a containment system that carries a refrigerated cargo must at least...

  16. 46 CFR 153.436 - Heat transfer fluids: compatibility with cargo. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Heat transfer fluids: compatibility with cargo. 153.436... Equipment Cargo Temperature Control Systems § 153.436 Heat transfer fluids: compatibility with cargo. A heat transfer fluid separated from the cargo by only one wall (for example, the heat transfer fluid in a coil...

  17. The Liner Shipping Fleet Repositioning Problem with Cargo Flows

    DEFF Research Database (Denmark)

    Tierney, Kevin; Jensen, Rune Møller


    to reposition vessels as cheaply as possible without disrupting the cargo flows of the network. The LSFRP is characterized by chains of interacting activities with a multi-commodity flow over paths defined by the activities chosen. Despite its great industrial importance, the LSFRP has received little attention...... in the literature. We introduce a novel mathematical model of the LSFRP with cargo flows based on a carefully constructed graph and evaluate it on real world data from our industrial collaborator....

  18. The Cargo Tray Industry in India – A Market Research


    Eriksson, Martin; Ohlsson, Tobias


    Title: The Cargo Tray Industry in India – A Market Research Authors: Martin Eriksson and Tobias Ohlsson Supervisor: Cecilia Lindh University: University of MälardalenDepartment: School of Sustainable Development of Society and TechnologyCourse: Bachelor thesis in Business Administration, 15 credits Research question: Is the Indian cargo tray industry a promising place for Autoform to make futureinvestments? Target group: The primary target is Autoform. The secondary target group is other cara...

  19. Audible Noise Design of ISS Cargo Module "Cygnus" (United States)

    Destefanis, Stefano; Paron, Alberto; Bandini, Flavio


    Orbital developed the Cygnus advanced manoeuvring spacecraft to demonstrate cargo delivery services under a NASA Commercial Orbital Transportation Services (COTS) Space Act Agreement.In addition to the COTS development and demonstration program, Orbital will utilize Cygnus to perform ISS resupply flights under the Commercial Resupply Service (CRS) contract.Starting in January 2014 Orbital launched its first of eight missions to deliver approximately 20,000 kilograms of cargo to the ISS (International Space Station). Cygnus will carry crew supplies, spares and scientific experiments to the ISS.Cygnus consists of a common service module and a pressurized cargo module. The pressurized cargo module is based on the Multi-Purpose Logistics Module (MPLM), developed by Thales Alenia Space for NASA. Since Cygnus pressurized cargo module will host astronauts performing daily tasks, it is required to be compliant with NASA guidelines related to acoustic comfort (working areas noise not to exceed NC-50 requirement) and safety (caution and warning alarms audibility).The main source of noise inside Cygnus is the ventilation fan, which happens to be the same model already installed on the ATV (Automated Transfer Vehicle) cargo module: however, the strategy adopted to limit its acoustic disturbance had to be differently tailored.This paper presents the activities (assumptions, design, characterization, testing) that led to define the type of noise control devices used on Cygnus, up to its first successful flight (module labelled "PCM0") to the ISS, where it reached 2nd place in the "quietest visiting modules" ranking.

  20. Radiation effects in bulk silicon (United States)

    Claeys, Cor; Vanhellemont, Jan


    This paper highlights important aspects related to irradiation effects in bulk silicon. Some basic principles related to the interaction of radiation with material, i.e. ionization and atomic displacement, are briefly reviewed. A physical understanding of radiation effects strongly depends on the availability of appropriate analytical tools. These tools are critically accessed from a silicon bulk viewpoint. More detailed information, related to the properties of the bulk damage and some dedicated application aspects, is given for both electron and proton irradiations. Emphasis is placed on radiation environments encountered during space missions and on their influence on the electrical performance of devices such as memories and image sensors.

  1. Влияние пыли перегружаемых в портах опасных навалочных грузов на санитарно-экологическое состояния почв припортовых городов причерноморья = Influence of dust transferred into ports of dangerous cargos for bulk sanitary-ecological condition of soils port urban Black Sea


    Belobrov, E. P.; Zambriborshch, M. S.; Sidorenko, S. G.; Zukow, W.


    Belobrov E. P., Zambriborshch M. S., Sidorenko S. G., Zukow W. Влияние пыли перегружаемых в портах опасных навалочных грузов на санитарно-экологическое состояния почв припортовых городов причерноморья = Influence of dust transferred into ports of dangerous cargos for bulk sanitary-ecological condition of soils port urban Black Sea. Journal of Education, Health and Sport. 2015;5(7):604-619. ISSN 2391-8306. DOI

  2. Failure of cargo aileron’s actuator

    Directory of Open Access Journals (Sweden)

    G. Zucca


    Full Text Available During a ferry flight, in a standard operation condition and at cruising level, a military cargo experienced a double hydraulic system failure due to a structural damage of the dual booster actuator. The booster actuator is the main component in mechanism of aileron’s deflection. The crew was able to arrange an emergency landing thanks to the spare oil onboard: load specialists refilled the hydraulic reservoirs. Due to safety concerns and in order to prevent the possibility of other similar incidents, a technical investigation took place. The study aimed to carry out the analysis of root causes of the actuator failure. The Booster actuator is composed mainly by the piston rod and its aluminum external case (AA7049. The assembly has two bronze caps on both ends. These are fixed in position by means of two retainers. At one end of the actuator case is placed a trunnion: a cylindrical protrusion used as a pivoting point on the aircraft. The fracture was located at one end of the case, on the trunnion side, in correspondence to the cap and over the retainer. One of the two fracture surfaces was found separated to the case and with the cap entangled inside. The fracture surfaces of the external case indicated fatigue crack growth followed by ductile separation. The failure analysis was performed by means of optical, metallographic, digital and electronic microscopy. The collected evidences showed a multiple initiation fracture mechanism. Moreover, 3D scanner reconstruction and numerical simulation demonstrated that dimensional non conformances and thermal loads caused an abnormal stress concentration. Stress concentration was located along the case assy outer surface where the fatigue crack originated. The progressive rupture mechanism grew under cyclical axial load due to the normal operations. Recommendations were issued in order to improve dimensional controls and assembly procedures during production and overhaul activities.

  3. Silicon Bulk Micromachined Vibratory Gyroscope (United States)

    Tang, T. K.; Gutierrez, R. C.; Wilcox, J. Z.; Stell, C.; Vorperian, V.; Calvet, R.; Li, W. J.; Charkaborty, I.; Bartman, R.; Kaiser, W. J.


    This paper reports on design, modeling, fabrication, and characterization of a novel silicon bulk micromachined vibratory rate gyroscope designed for microspacecraft applications. The new microgyroscope consists of a silicon four leaf cloverstructure with a post attached to the center.

  4. Proceedings of BulkTrans '89

    Energy Technology Data Exchange (ETDEWEB)


    Papers were presented on bulk commodity demand; steel industry bulk trades; grains and the world food economy; steam coal and cement demand; shipping profitability; bulk carrier design and economics; bulk ports and terminals; ship unloading; computers in bulk terminals; and conveyors and stockyard equipment.

  5. Combatting bulking sludge with ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Wuensch, B.; Heine, W.; Neis, U. [Technische Univ. Hamburg-Harburg, Hamburg (Germany). Dept. of Sanitary and Environmental Engineering


    Bulking and floating sludge cause great problems in many waste water treatment plants with biological nutrient removal. The purification as well as the sludge digestion process can be affected. These problems are due to the interlaced structure of filamentous microorganisms, which have an impact on the sludge's settling behaviour. Foam is able to build up a stable layer, which does not settle in the secondary clarifier. Foam in digestion causes a reduction of the degree of stabilisation and of the biogas production. We use low-frequency ultrasound to combat filamentous organisms in bulking sludge. Low-frequency ultrasound is suitable to create high local shear stresses, which are capable of breaking the filamentous structures of the sludge. After preliminary lab-scale tests now a full-scale new ultrasound equipment is operating at Reinfeld sewage treatment plant, Germany. The objective of this study is to explore the best ultrasound configuration to destroy the filamentous structure of bulking and foaming sludge in a substainable way. Later this study will also look into the effects of ultrasound treated bulking sludge on the anaerobic digestion process. Up to now results show that the settling behaviour of bulking sludge is improved. The minimal ultrasound energy input for destruction of bulking structure was determined. (orig.)

  6. Cargo binding activates myosin VIIA motor function in cells. (United States)

    Sakai, Tsuyoshi; Umeki, Nobuhisa; Ikebe, Reiko; Ikebe, Mitsuo


    Myosin VIIA, thought to be involved in human auditory function, is a gene responsible for human Usher syndrome type 1B, which causes hearing and visual loss. Recent studies have suggested that it can move processively if it forms a dimer. Nevertheless, it exists as a monomer in vitro, unlike the well-known two-headed processive myosin Va. Here we studied the molecular mechanism, which is currently unknown, of activating myosin VIIA as a cargo-transporting motor. Human myosin VIIA was present throughout cytosol, but it moved to the tip of filopodia upon the formation of dimer induced by dimer-inducing reagent. The forced dimer of myosin VIIA translocated its cargo molecule, MyRip, to the tip of filopodia, whereas myosin VIIA without the forced dimer-forming module does not translocate to the filopodial tips. These results suggest that dimer formation of myosin VIIA is important for its cargo-transporting activity. On the other hand, myosin VIIA without the forced dimerization module became translocated to the filopodial tips in the presence of cargo complex, i.e., MyRip/Rab27a, and transported its cargo complex to the tip. Coexpression of MyRip promoted the association of myosin VIIA to vesicles and the dimer formation. These results suggest that association of myosin VIIA monomers with membrane via the MyRip/Rab27a complex facilitates the cargo-transporting activity of myosin VIIA, which is achieved by cluster formation on the membrane, where it possibly forms a dimer. Present findings support that MyRip, a cargo molecule, functions as an activator of myosin VIIA transporter function.

  7. Spectroscopic neutron radiography for a cargo scanning system

    Energy Technology Data Exchange (ETDEWEB)

    Rahon, Jill [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Danagoulian, Areg, E-mail: [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); MacDonald, Thomas D. [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Hartwig, Zachary S. [Plasma Science and Fusion Center, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Lanza, Richard C. [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States)


    Detection of cross-border smuggling of illicit materials and contraband is a challenge that requires rapid, low-dose, and efficient radiographic technology. The work we describe here is derived from a technique which uses monoenergetic gamma rays from low energy nuclear reactions, such as {sup 11}B(d,nγ){sup 12}C, to perform radiographic analysis of shipping containers. Transmission ratios of multiple monoenergetic gamma lines resulting from several gamma producing nuclear reactions can be employed to detect materials of high atomic number (Z), the details of which will be described in a separate paper. Inherent in this particular nuclear reaction is the production of fast neutrons which could enable neutron radiography and further characterization of the effective-Z of the cargo, especially within the range of lower Z. Previous research efforts focused on the use of total neutron counts in combination with X-ray radiography to characterize the hydrogenous content of the cargo. We present a technique of performing transmitted neutron spectral analysis to reconstruct the effective Z and potentially the density of the cargo. This is made possible by the large differences in the energy dependence of neutron scattering cross-sections between hydrogenous materials and those of higher Z. These dependencies result in harder transmission spectra for hydrogenous cargoes than those of non-hydrogenous cargoes. Such observed differences can then be used to classify the cargo based on its hydrogenous content. The studies presented in this paper demonstrate that such techniques are feasible and can provide a contribution to cargo security, especially when used in concert with gamma radiography.

  8. Modelling of bulk superconductor magnetization (United States)

    Ainslie, M. D.; Fujishiro, H.


    This paper presents a topical review of the current state of the art in modelling the magnetization of bulk superconductors, including both (RE)BCO (where RE = rare earth or Y) and MgB2 materials. Such modelling is a powerful tool to understand the physical mechanisms of their magnetization, to assist in interpretation of experimental results, and to predict the performance of practical bulk superconductor-based devices, which is particularly important as many superconducting applications head towards the commercialization stage of their development in the coming years. In addition to the analytical and numerical techniques currently used by researchers for modelling such materials, the commonly used practical techniques to magnetize bulk superconductors are summarized with a particular focus on pulsed field magnetization (PFM), which is promising as a compact, mobile and relatively inexpensive magnetizing technique. A number of numerical models developed to analyse the issues related to PFM and optimise the technique are described in detail, including understanding the dynamics of the magnetic flux penetration and the influence of material inhomogeneities, thermal properties, pulse duration, magnitude and shape, and the shape of the magnetization coil(s). The effect of externally applied magnetic fields in different configurations on the attenuation of the trapped field is also discussed. A number of novel and hybrid bulk superconductor structures are described, including improved thermal conductivity structures and ferromagnet-superconductor structures, which have been designed to overcome some of the issues related to bulk superconductors and their magnetization and enhance the intrinsic properties of bulk superconductors acting as trapped field magnets. Finally, the use of hollow bulk cylinders/tubes for shielding is analysed.

  9. Capacity utilization study for aviation security cargo inspection queuing system (United States)

    Allgood, Glenn O.; Olama, Mohammed M.; Lake, Joe E.; Brumback, Daryl


    In this paper, we conduct performance evaluation study for an aviation security cargo inspection queuing system for material flow and accountability. The queuing model employed in our study is based on discrete-event simulation and processes various types of cargo simultaneously. Onsite measurements are collected in an airport facility to validate the queuing model. The overall performance of the aviation security cargo inspection system is computed, analyzed, and optimized for the different system dynamics. Various performance measures are considered such as system capacity, residual capacity, throughput, capacity utilization, subscribed capacity utilization, resources capacity utilization, subscribed resources capacity utilization, and number of cargo pieces (or pallets) in the different queues. These metrics are performance indicators of the system's ability to service current needs and response capacity to additional requests. We studied and analyzed different scenarios by changing various model parameters such as number of pieces per pallet, number of TSA inspectors and ATS personnel, number of forklifts, number of explosives trace detection (ETD) and explosives detection system (EDS) inspection machines, inspection modality distribution, alarm rate, and cargo closeout time. The increased physical understanding resulting from execution of the queuing model utilizing these vetted performance measures should reduce the overall cost and shipping delays associated with new inspection requirements.

  10. Optimisation of key performance measures in air cargo demand management

    Directory of Open Access Journals (Sweden)

    Alexander May


    Full Text Available This article sought to facilitate the optimisation of key performance measures utilised for demand management in air cargo operations. The focus was on the Revenue Management team at Virgin Atlantic Cargo and a fuzzy group decision-making method was used. Utilising intelligent fuzzy multi-criteria methods, the authors generated a ranking order of ten key outcome-based performance indicators for Virgin Atlantic air cargo Revenue Management. The result of this industry-driven study showed that for Air Cargo Revenue Management, ‘Network Optimisation’ represents a critical outcome-based performance indicator. This collaborative study contributes to existing logistics management literature, especially in the area of Revenue Management, and it seeks to enhance Revenue Management practice. It also provides a platform for Air Cargo operators seeking to improve reliability values for their key performance indicators as a means of enhancing operational monitoring power.

  11. 46 CFR 151.05-2 - Compliance with requirements for tank barges carrying benzene and benzene containing cargoes, or... (United States)


    ... benzene and benzene containing cargoes, or butyl acrylate cargoes. 151.05-2 Section 151.05-2 Shipping... Compliance with requirements for tank barges carrying benzene and benzene containing cargoes, or butyl acrylate cargoes. A tank barge certificated to carry benzene and benzene containing cargoes or butyl...

  12. Multipurpose Cargo Transfer Bags fro Reducing Exploration Mission Logistics (United States)

    Baccus, Shelley; Broyan, James Lee, Jr.; Borrego, Melissa


    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) division is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag (CTB), the common logistics carrying bag for the International Space Station (ISS). After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unfolded into a flat panel for reuse. Concepts and potential benefits for various MCTB applications will be discussed including partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing. Acoustic MCTBs are currently in use on ISS to reduce the noise generated by the T2 treadmill, which reaches the hazard limit at high speeds. The development of the AMCTB included identification of keep out zones, acoustic properties, deployment considerations, and structural testing. Features developed for these considerations are applicable to MCTBs for all crew outfitting applications.

  13. Reducing Mission Logistics with Multipurpose Cargo Transfer Bags (United States)

    Baccus, Shelley; Broyan, James Lee, Jr.; Borrego, Melissa


    The Logistics Reduction (LR) project within Advanced Exploration Systems (AES) is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag (CTB), the common logistics carrying bag for the International Space Station (ISS). After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unfolded into a flat panel for reuse. Concepts and potential benefits for various MCTB applications will be discussed including partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing. Acoustic MCTBs are currently in use on ISS to reduce the noise generated by the T2 treadmill, which reaches the hazard limit at high speeds. The development of the AMCTB included identification of keep-out zones, acoustic properties, deployment considerations, and structural testing. Features developed for these considerations are applicable to MCTBs for all crew outfitting applications.

  14. Versatile Loading of Diverse Cargo into Functional Polymer Capsules. (United States)

    Richardson, Joseph J; Maina, James W; Ejima, Hirotaka; Hu, Ming; Guo, Junling; Choy, Mei Y; Gunawan, Sylvia T; Lybaert, Lien; Hagemeyer, Christoph E; De Geest, Bruno G; Caruso, Frank


    Polymer microcapsules are of particular interest for applications including self-healing coatings, catalysis, bioreactions, sensing, and drug delivery. The primary way that polymer capsules can exhibit functionality relevant to these diverse fields is through the incorporation of functional cargo in the capsule cavity or wall. Diverse functional and therapeutic cargo can be loaded into polymer capsules with ease using polymer-stabilized calcium carbonate (CaCO3) particles. A variety of examples are demonstrated, including 15 types of cargo, yielding a toolbox with effectively 500+ variations. This process uses no harsh reagents and can take less than 30 min to prepare, load, coat, and form the hollow capsules. For these reasons, it is expected that the technique will play a crucial role across scientific studies in numerous fields.

  15. Shared Value Potential of Transporting Cargo via Hyperloop

    Directory of Open Access Journals (Sweden)

    Max Werner


    Full Text Available This research estimates the shared value created by constructing a hypothetical Hyperloop to transport cargo along 300 km in Northern Germany. Following Porter-Kramer (2011, we identified and evaluated eight factors that create shared value: travel speed, operating costs, safety, noise pollution, air pollution, climate effect/carbon footprint, separation effect/ property efficiency, and maintenance. Using official data compiled by several German institutes and organizations, we conducted comparative analysis to quantify and compare the abovementioned factors for Hyperloop and over-the-road cargo transport in Germany. Then, we monetized the individual and collective benefits of the shared value created by Hyperloop replacing a significant share of cargo transported by truck. Our findings indicate that the hypothetical Hyperloop project in Northern Germany would create €660 to €900 million of shared value annually. Our research method establishes a framework for assessing future transportation projects like Hyperloop, and our findings can be generalized to industrialized nations beyond Germany.

  16. Container shipping service selection and cargo routing with transshipment limits

    DEFF Research Database (Denmark)

    Balakrishnan, Anantaram; Karsten, Christian Vad


    We address the tactical planning problem faced by container liner shipping companies to select a set of sailing services from a given pool of candidate services and route available cargo over the chosen services so as to maximize profit. One of the distinctive features of our model is that it inc......We address the tactical planning problem faced by container liner shipping companies to select a set of sailing services from a given pool of candidate services and route available cargo over the chosen services so as to maximize profit. One of the distinctive features of our model...... is that it incorporates limits on the number of transshipments for each container, a common service requirement in practice. These limits can vary by shipment attributes such as origin and destination, and cargo priority. We propose a new stage-indexed multi-commodity flow model that is based on an augmented network...

  17. Working out of generalized dynamic model of cargo fixation with cargo pads jointly with flexible and thrust elements under the action spatial force system

    Directory of Open Access Journals (Sweden)

    Khabibulla TURANOV


    Full Text Available The article gives an account of the results of working out a generalized dynamic model of fixation of cargo with pads jointly with flexible and thrust elements. Working out a generalized dynamic model of cargo fixation is rather a complicated problem not in the sense of solving differential equations systems but in the sense of presenting them as a complex mechanical system “cargo – pads – flexible elements – thrust bars”. Generalized dynamic model of cargo with pads observed that this model represents technology of joint work of flexible and thrust fastening means of cargo on rolling stock. In particular, on the basis of this model there can be obtained the technology models of joint work of flexible and elastic fastening means of cargo without pads of fastening flexible elements of cargo with pads without thrust bars and also flexible fastening elements of cargo without pads and thrust bars at asymmetrical and/or symmetrical allocation of cargo in the wagon. A specific feature (novelty feature of the proposed dynamic model is inclusion into the model of both cargo pads and thrust bars which are nailed to the wagon floor close to the butt and lateral sides of cargo.

  18. CH-47F Improved Cargo Helicopter (CH-47F) (United States)


    funding lines changed starting in FY 2010 to CH-47 Helicopter (A05101) - a parent (roll-up) of New Build and Service Life Extension Program (SLEP...Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-278 CH-47F Improved Cargo Helicopter (CH-47F) As of FY 2017 President’s Budget Defense...December 2015 SAR March 21, 2016 18:18:21 UNCLASSIFIED 4 LTC Richard Bratt Office of the Project Manager Cargo Helicopters Building 5678 Redstone Arsenal

  19. Solving the Liner Shipping Fleet Repositioning Problem with Cargo Flows

    DEFF Research Database (Denmark)

    Tierney, Kevin; Askelsdottir, Björg; Jensen, Rune Møller


    to reposition vessels as cheaply as possible without disrupting cargo flows. The LSFRP is characterized by chains of interacting activities with a multicommodity flow over paths defined by the activities chosen. Despite its industrial importance, the LSFRP has received little attention in the literature. We...... introduce a novel mathematical model and a simulated annealing algorithm for the LSFRP with cargo flows that makes use of a carefully constructed graph; we evaluate these approaches using real-world data from our industrial collaborator. Additionally, we compare the performance of our approach against...

  20. Shift designs for freight handling personnel at air cargo terminals

    DEFF Research Database (Denmark)

    Rong, Aiying; Grunow, Martin


    This paper presents an integrated mixed integer linear programming (MILP) model for determining manpower requirements and related personnel shift designs for the build-up and break-down of the unit load devices (ULDs) at the air cargo terminal to minimize manpower costs. To utilize the manpower...... resources efficiently, we implement a new mechanism for demand leveling. In addition, we consider the qualification hierarchy between build-up and break-down workers. A case study based on the real-life data shows that the model is useful for manpower planning at air cargo terminals and the integrated...

  1. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja


    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise...

  2. Bulk fields with brane terms

    Energy Technology Data Exchange (ETDEWEB)

    Aguila, F. del [Departamento de Fisica Teorica y del Cosmos and Centro Andaluz de Fisica de Particulas Elementales (CAFPE), Universidad de Granada, E-18071 Granada (Spain); Perez-Victoria, M. [Dipartimento di Fisica ' ' G. Galilei' ' , Universita di Padova and INFN, Sezione di Padova, Via Marzolo 8, I-35131 Padua (Italy); Santiago, J. [Institute for Particle Physics Phenomenology, University of Durham, South Road, Durham DH1 3LE (United Kingdom)


    In theories with branes, bulk fields get in general divergent corrections localized on these defects. Hence, the corresponding brane terms are renormalized and should be included in the effective theory from the very beginning. We review the phenomenology associated to brane kinetic terms for different spins and backgrounds, and point out that renormalization is required already at the classical level. (orig.)

  3. 49 CFR 178.320 - General requirements applicable to all DOT specification cargo tank motor vehicles. (United States)


    ... determine leak tightness of the cargo tank when testing with pneumatic pressure. Internal self-closing stop... tank to a motor vehicle or to a motor vehicle suspension component that involves welding on the cargo...

  4. 49 CFR 178.347 - Specification DOT 407; cargo tank motor vehicle. (United States)


    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 407; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.347 Specification DOT 407; cargo tank motor vehicle. ...

  5. 49 CFR 178.346 - Specification DOT 406; cargo tank motor vehicle. (United States)


    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 406; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.346 Specification DOT 406; cargo tank motor vehicle. ...

  6. 49 CFR 178.348 - Specification DOT 412; cargo tank motor vehicle. (United States)


    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 412; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.348 Specification DOT 412; cargo tank motor vehicle. ...

  7. 49 CFR 180.405 - Qualification of cargo tanks. (United States)


    ... specification in accordance with the reporting and record retention provisions of § 180.417. The certification... automatic heat activated means. (B) For a cargo tank used in corrosive service, the remote means of closure... structure of the bumper must be designed in accordance with § 178.345-8(d)(3) of this subchapter. (m...

  8. Installation of the Canadian Muon Cargo Inspection System at CRL (United States)


    Cradle Assembly ................................................................................................ B-1 Appendix C Spectrometer...imaging techniques [5] in computed axial tomography ( CAT ). Although AECL has developed its own mathematical tools to image components in cargo that...detector modules are maintained in place in an upper and lower cradle , shown in grey in the figure. The yellow structure, thick iron slabs, forms, with

  9. 77 FR 65395 - Air Cargo Advance Screening (ACAS) Pilot Program (United States)


    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Air Cargo Advance Screening (ACAS) Pilot Program Correction In notice document 2012-26031 appearing on pages 65006-65009 in the issue of October 24, 2012 make the...

  10. DUKW 21 - Amphibious Cargo Transfer from Ship to Shore (United States)


    a slender layout which is favorable for decreased water resistance ( AAAV design). The size of the tracks has a very large impact on the SWATH...Program DUKW 21 - Amphibious cargo transfer from ship to shore 31 Bibliography AAAV Design. Advance Amphibious Assault Vehicle Final Report Vol. 1

  11. Risk analysis of fireworks transport in cargo container ships


    Branka, Ruddy; Marlair, Guy; Nedelec, Brigitte


    International audience; The study deals with the analysis of the most suitable configuration for positioning the fireworks containers in the cargo ship in order to minimize the risks for the ship in case of an accident (transmission of fire or deflagration originating from containers filled with fireworks devices to other containers or arising from other containers to the those containing fireworks).

  12. 75 FR 35318 - Cargo Insurance for Property Loss or Damage (United States)


    ... commenters asserted that the elimination of mandatory cargo insurance will raise the transaction costs for... & Associates; Transportation and Logistics Council; T.D.L. Associates Commerce Consultant; National Small... Association; National Conference of State Transportation Specialists; Third Party Logistics Providers; Certain...

  13. 49 CFR 175.75 - Quantity limitations and cargo location. (United States)


    ... loaded in an inaccessible manner. These requirements do not apply to Class 9 and ORM-D materials. (d...), Division 6.1 (except those also labeled FLAMMABLE), Division 6.2, Class 7, Class 9 or ORM-D. (2) Division 2... materials. These requirements do not apply to Class 9 or ORM-D materials. For cargo aircraft only packages...

  14. A consolidation model for cargo-driven intermodal transportation

    NARCIS (Netherlands)

    Behdani, B.; Zuidwijk, R.A.


    Accessibility of main sea ports by road has become increasingly difficult due to rapid growth in container throughput. To deal with this challenge, new ways for handling containers and distribution of cargo flows are needed to define and implement. One possibility is going beyond container

  15. Study on Alternative Cargo Launch Options from the Lunar Surface

    Energy Technology Data Exchange (ETDEWEB)

    Cheryl A. Blomberg; Zamir A. Zulkefli; Spencer W. Rich; Steven D. Howe


    In the future, there will be a need for constant cargo launches from Earth to Mars in order to build, and then sustain, a Martian base. Currently, chemical rockets are used for space launches. These are expensive and heavy due to the amount of necessary propellant. Nuclear thermal rockets (NTRs) are the next step in rocket design. Another alternative is to create a launcher on the lunar surface that uses magnetic levitation to launch cargo to Mars in order to minimize the amount of necessary propellant per mission. This paper investigates using nuclear power for six different cargo launching alternatives, as well as the orbital mechanics involved in launching cargo to a Martian base from the moon. Each alternative is compared to the other alternative launchers, as well as compared to using an NTR instead. This comparison is done on the basis of mass that must be shipped from Earth, the amount of necessary propellant, and the number of equivalent NTR launches. Of the options, a lunar coil launcher had a ship mass that is 12.7% less than the next best option and 17 NTR equivalent launches, making it the best of the presented six options.

  16. Alternative Concepts for Managing the Distribution of Resupply Cargo (United States)


    schedules. Surface transportation obeys the reverse logic: Vehicle schedules accommodate cargo routing. The resulting system suffers its greatest...Plan LSAO Logistcs Systems Analysis Office MAC Military Airlift Command MII.STRIP Military Standard Requisitioning and Issue Procedures MODELS...Modernization of Defens Logistc Standard Systems MSC Military Sealif Command MTMC Military Traffic Management Command NICPs National inventory control points

  17. Phototriggered cargo release from virus-like assemblies

    NARCIS (Netherlands)

    Brasch, M.; Voets, I.K.; Koay, M.S.T.; Cornelissen, Jeroen Johannes Lambertus Maria


    There has been tremendous progress towards the development of responsive polymers that are programmed to respond to an external stimulus such as light, pH and temperature. The unique combination of molecular packaging followed by slow, controlled release of molecular cargo is of particular

  18. Integrated cargo routing and ship scheduling in liner shipping

    DEFF Research Database (Denmark)

    Kjeldsen, Karina Hjortshøj

    The problem consists of creating routes and schedules for a heterogeneous fleet of ships while determining the cargo routing and the speed for all relevant port pair/ship combinations. Transshipment is allowed in ports with transshipment capabilities. The service frequency is fixed at one week...

  19. Hepatitis Virus Capsid Polymorph Stability Depends on Encapsulated Cargo Size

    NARCIS (Netherlands)

    He, L.; Porterfield, Z.; van der Schoot, P. P. A. M.|info:eu-repo/dai/nl/102140618; Zlotnick, A.; Dragnea, B.


    Protein cages providing a controlled environment to encapsulated cargo are a ubiquitous presence in any biological system. Well-known examples are capsids, the regular protein shells of viruses, which protect and deliver the viral genome. Since some virus capsids can be loaded with nongenomic

  20. 48 CFR 752.228-9 - Cargo insurance. (United States)


    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Cargo insurance. 752.228-9... insurance. As prescribed in 728.313(a), the following preface is to be used preceding the text of the clause at FAR 52.228-9: Preface: To the extent that marine insurance is necessary or appropriate under this...

  1. Magnetic Microlassos for Reversible Cargo Capture, Transport, and Release. (United States)

    Yang, Tao; Tasci, Tonguc O; Neeves, Keith B; Wu, Ning; Marr, David W M


    Microbot propulsion has seen increasing interest in recent years as artificial methods that overcome the well-established reversible and challenging nature of microscale fluid mechanics. While controlled movement is an important feature of microbot action, many envisioned applications also involve cargo transport where microbots must be able to load and unload contents on command while tolerating complex solution chemistry. Here we introduce a physical method that uses flexible and linked superparamagnetic colloidal chains, which can form closed rings or "lassos" in the presence of a planar rotating magnetic field. By adding an additional AC magnetic field along the direction perpendicular to the substrate, we can orient the lasso at a tilted camber angle. We show that these magnetic lassos can roll at substantial velocities, with precise spatial control by manipulating both field strength and phase lag. Moreover, the lasso can curl around and capture cargo tightly and transport it based on a wheel-type mechanism. At the targeted destination, cargo is easily released upon field removal and the lasso can be readily reused. Since the entire process is physically controlled with no chemistry for attachment or disengagement involved, our system can potentially be used for transporting diverse types of cargo under different solution conditions.

  2. 33 CFR 105.265 - Security measures for handling cargo. (United States)


    ... documentation; (3) Screen vehicles; and (4) Check seals and other methods used to prevent tampering upon... tampering; (2) Intensifying checks, as appropriate, to ensure that only the documented cargo enters the facility, is temporarily stored there, and then loaded onto the vessel; (3) Intensifying the screening of...

  3. 76 FR 41278 - Cargo Security Risk Reduction; Public Listening Sessions (United States)


    ... SECURITY Coast Guard Cargo Security Risk Reduction; Public Listening Sessions AGENCY: Coast Guard, DHS... public and private sector stakeholders, across the Security Spectrum.\\1\\ \\1\\ The Security Spectrum... progress and development of a CDC Security National Strategy to reduce risks associated with the transport...

  4. Transportation of Nanoscale Cargoes by Myosin Propelled Actin Filaments

    NARCIS (Netherlands)

    Persson, Malin; Gullberg, Maria; Tolf, Conny; Lindberg, A. Michael; Mansson, Alf; Kocer, Armagan


    Myosin II propelled actin filaments move ten times faster than kinesin driven microtubules and are thus attractive candidates as cargo-transporting shuttles in motor driven lab-on-a-chip devices. In addition, actomyosin-based transportation of nanoparticles is useful in various fundamental studies.

  5. The Army’s Cargo Fleet in World War II (United States)


    light--principally because of much " ballon " cargo in the form or assembled vehicles ana aircraft. The Army an~c Navy supply agencies were cooperating...Guards to cope with the enemy. The dis- parity between the modest pay of the Navy gun crew and the war- inflated wages of the seamen frequently led to ill

  6. 78 FR 21037 - Special Conditions: Airbus Model A330-200 Airplanes; Bulk Cargo Lower Deck Crew Rest Compartments (United States)


    ... to minimize the possibility of blockage, which might result from fire, mechanical or structural... designed such that fires within the compartment can be controlled without a crew member having to enter the..., considering the fire threat, volume of the compartment, and the ventilation rate. 13. There must be a...

  7. 46 CFR 154.650 - Cargo tank and process pressure vessel welding. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank and process pressure vessel welding. 154.650... Equipment Construction § 154.650 Cargo tank and process pressure vessel welding. (a) Cargo tank and process pressure vessel welding must meet Subpart 54.05 and Part 57 of this chapter. (b) Welding consumables used...

  8. 19 CFR 123.91 - Electronic information for rail cargo required in advance of arrival. (United States)


    ... for Cargo Arriving by Rail or Truck § 123.91 Electronic information for rail cargo required in advance.... Specifically, to effect the advance electronic transmission of the required rail cargo information to CBP, the... States from point to point in the same foreign country are subject to the advance electronic information...

  9. 46 CFR 189.60-5 - Cargo Ship Safety Construction Certificate. (United States)


    ... 46 Shipping 7 2010-10-01 2010-10-01 false Cargo Ship Safety Construction Certificate. 189.60-5..., 1974 § 189.60-5 Cargo Ship Safety Construction Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Construction Certificate. This certificate shall be issued by...

  10. 46 CFR 31.40-5 - Cargo Ship Safety Construction Certificate-T/ALL. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo Ship Safety Construction Certificate-T/ALL. 31.40... a Cargo Ship Safety Construction Certificate. This certificate shall be issued by the U.S. Coast... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-5 Cargo Ship...

  11. 46 CFR 91.60-5 - Cargo Ship Safety Construction Certificate. (United States)


    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo Ship Safety Construction Certificate. 91.60-5..., 1974 § 91.60-5 Cargo Ship Safety Construction Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Construction Certificate. This certificate shall be issued by...

  12. 46 CFR 154.706 - Cargo boil-off as fuel: Fuel lines. (United States)


    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo boil-off as fuel: Fuel lines. 154.706 Section 154... Equipment Cargo Pressure and Temperature Control § 154.706 Cargo boil-off as fuel: Fuel lines. (a) Gas fuel lines must not pass through accommodation, service, or control spaces. Each gas fuel line passing...

  13. 29 CFR 1918.83 - Stowed cargo; tiering and breaking down. (United States)


    ... 29 Labor 7 2010-07-01 2010-07-01 false Stowed cargo; tiering and breaking down. 1918.83 Section... cargo; tiering and breaking down. (a) When necessary to protect personnel working in a hold, the employer shall secure or block stowed cargo that is likely to shift or roll. (b) In breaking down stowed...

  14. Bulk density of small meteoroids (United States)

    Kikwaya, J.-B.; Campbell-Brown, M.; Brown, P. G.


    Aims: Here we report on precise metric and photometric observations of 107 optical meteors, which were simultaneously recorded at multiple stations using three different intensified video camera systems. The purpose is to estimate bulk meteoroid density, link small meteoroids to their parent bodies based on dynamical and physical density values expected for different small body populations, to better understand and explain the dynamical evolution of meteoroids after release from their parent bodies. Methods: The video systems used had image sizes ranging from 640 × 480 to 1360 × 1036 pixels, with pixel scales from 0.01° per pixel to 0.05° per pixel, and limiting meteor magnitudes ranging from Mv = +2.5 to +6.0. We find that 78% of our sample show noticeable deceleration, allowing more robust constraints to be placed on density estimates. The density of each meteoroid is estimated by simultaneously fitting the observed deceleration and lightcurve using a model based on thermal fragmentation, conservation of energy and momentum. The entire phase space of the model free parameters is explored for each event to find ranges of parameters which fit the observations within the measurement uncertainty. Results: (a) We have analysed our data by first associating each of our events with one of the five meteoroid classes. The average density of meteoroids whose orbits are asteroidal and chondritic (AC) is 4200 kg m-3 suggesting an asteroidal parentage, possibly related to the high-iron content population. Meteoroids with orbits belonging to Jupiter family comets (JFCs) have an average density of 3100 ± 300 kg m-3. This high density is found for all meteoroids with JFC-like orbits and supports the notion that the refractory material reported from the Stardust measurements of 81P/Wild 2 dust is common among the broader JFC population. This high density is also the average bulk density for the 4 meteoroids with orbits belonging to the Ecliptic shower-type class (ES) also

  15. Bulk Moisture and Salinity Sensor (United States)

    Nurge, Mark; Monje, Oscar; Prenger, Jessica; Catechis, John


    Measurement and feedback control of nutrient solutions in plant root zones is critical to the development of healthy plants in both terrestrial and reduced-gravity environments. In addition to the water content, the amount of fertilizer in the nutrient solution is important to plant health. This typically requires a separate set of sensors to accomplish. A combination bulk moisture and salinity sensor has been designed, built, and tested with different nutrient solutions in several substrates. The substrates include glass beads, a clay-like substrate, and a nutrient-enriched substrate with the presence of plant roots. By measuring two key parameters, the sensor is able to monitor both the volumetric water content and salinity of the nutrient solution in bulk media. Many commercially available moisture sensors are point sensors, making localized measurements over a small volume at the point of insertion. Consequently, they are more prone to suffer from interferences with air bubbles, contact area of media, and root growth. This makes it difficult to get an accurate representation of true moisture content and distribution in the bulk media. Additionally, a network of point sensors is required, increasing the cabling, data acquisition, and calibration requirements. measure the dielectric properties of a material in the annular space of the vessel. Because the pore water in the media often has high salinity, a method to measure the media moisture content and salinity simultaneously was devised. Characterization of the frequency response for capacitance and conductance across the electrodes was completed for 2-mm glass bead media, 1- to 2-mm Turface (a clay like media), and 1- to 2-mm fertilized Turface with the presence of root mass. These measurements were then used to find empirical relationships among capacitance (C), the dissipation factor (D), the volumetric water content, and the pore water salinity.

  16. Gold based bulk metallic glass


    Schroers, Jan; Lohwongwatana, Boonrat; Johnson, William L.; Peker, Atakan


    Gold-based bulk metallic glass alloys based on Au-Cu-Si are introduced. The alloys exhibit a gold content comparable to 18-karat gold. They show very low liquidus temperature, large supercooled liquid region, and good processibility. The maximum casting thickness exceeds 5 mm in the best glassformer. Au49Ag5.5Pd2.3Cu26.9Si16.3 has a liquidus temperature of 644 K, a glass transition temperature of 401 K, and a supercooled liquid region of 58 K. The Vickers hardness of the alloys in this system...

  17. Winged cargo return vehicle. Volume 1: Conceptual design (United States)


    The Advanced Design Project (ADP) allows an opportunity for students to work in conjunction with NASA and other aerospace companies on NASA Advanced Design Projects. The following volumes represent the design report: Volume 1 Conceptual Design; Volume 2 Wind Tunnel Tests; Volume 3 Structural Analysis; and Volume 4 Water Tunnel Tests. The project chosen by the University of Minnesota in conjunction with NASA Marshall Space Flight Center for this year is a Cargo Return Vehicle (CRV) to support the Space Station Freedom. The vehicle is the third generation of vehicles to be built by NASA, the first two being the Apollo program, and the Space Shuttle program. The CRV is to work in conjunction with a personnel launch system (PLS) to further subdivide and specialize the vehicles that NASA will operate in the year 2000. The cargo return vehicle will carry payload to and from the Space Station Freedom (SSF).

  18. Fixing Trailer Hitch for Roof Rack of Cargos

    Directory of Open Access Journals (Sweden)

    Darina Matisková


    Full Text Available This article presents a new technical solution of fixing trailer hitch which serves as a connection between single track vehicle and cargo, mainly light trailer. They are manufactured from steel girder and nets which are constructed by point welding. They are designed to indicate the necessary solidity and the required load bearing capacity of the cargo. The application of roof racks is universal and these products are in great demand in the field of game management. There are a lot of trailer hitches which the manufacturers tailor to customers´ demands. The stated technical solution is subject of published industrial utility model at the Industrial property office of the Slovak republic.

  19. Implementation of cargo MagLev in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Rose, Chris R [Los Alamos National Laboratory; Peterson, Dean E [Los Alamos National Laboratory; Leung, Eddie M [MAGTEC ENGINEERING


    Numerous studies have been completed in the United States, but no commercial MagLev systems have been deployed. Outside the U.S., MagLev continues to attract funding for research, development and implementation. A brief review of recent global developments in MagLev technology is given followed by the status of MagLev in the U.S. The paper compares the cost of existing MagLev systems with other modes of transport, notes that the near-term focus of MagLev development in the U.S. should be for cargo, and suggests that future MagLev systems should be for very high speed cargo. The Los Angeles to Port of Los Angeles corridor is suggested as a first site for implementation. The benefits of MagLev are described along with suggestions on how to obtain funding.

  20. Shared Value Potential of Transporting Cargo via Hyperloop


    Werner, Max; Eissing, Klaus; Langton, Sebastian


    This research estimates the shared value created by constructing a hypothetical Hyperloop to transport cargo along 300 km in Northern Germany. Following Porter and Kramer (2011, 2012), we identified and evaluated eight factors that create shared value: travel speed, operating costs, safety, noise pollution, air pollution, climate effect/carbon footprint, separation effect/property efficiency, and maintenance. Using official data compiled by several German institutes and organizations, we cond...

  1. Development of a Sonar Oil Tanker Cargo Measurement System. (United States)


    pinciple classification societies are Lloyd’s registry, London; Bureau Veritas, Paris; British Corporation, Glasgow : Ger- manischer Lloyd, Berlin...the American Petroleum Institute (API) Committee on Marine Accountability ( COMA ). The body concerned with cargo measurement, stated that "we do not...redefinition 151 r I of the traditional concept of "freedom of passage," escala - ting cost of oil, and lack of viable alternatives, the addi- tional expense

  2. Optimizing an undulating magnetic microswimmer for cargo towing (United States)

    Or, Yizhar; Gutman, Emiliya


    One of the promising applications of robotic microswimmers is towing a cargo for controlled drug delivery, micro-surgery or tumor detection. This capability has been demonstrated by the magnetically-actuated microswimmer of Dreyfus et al. [Nature 2005] in which a red blood cell was attached to a chain of magnetic beads connected by flexible DNA links. A key question is what should be the optimal size of the magnetic tail for towing a given cargo. This question is addressed here for the simplest theoretical model of a magnetic microswimmer under planar undulations - a spherical load connected by a torsion spring to a magnetized rigid slender link. The swimmer's dynamics is formulated assuming negligible hydrodynamic interaction and leading-order expressions for the resulting motion are obtained explicitly under small amplitude approximation. Optimal combinations of magnetic actuation frequency, torsion stiffness, and tail length for maximizing displacement or average speed are obtained. The theoretical results are compared with several reported magnetic microswimmers, and also agree qualitatively with recent results on cargo towing by screw rotation of magnetic helical tails [Walker et al., ACS Nano Letters 2015]. This work is supported by the Israeli Science Foundation (ISF) under Grant No. 567/14.

  3. Compressed Sensing Techniques Applied to Ultrasonic Imaging of Cargo Containers

    Directory of Open Access Journals (Sweden)

    Yuri Álvarez López


    Full Text Available One of the key issues in the fight against the smuggling of goods has been the development of scanners for cargo inspection. X-ray-based radiographic system scanners are the most developed sensing modality. However, they are costly and use bulky sources that emit hazardous, ionizing radiation. Aiming to improve the probability of threat detection, an ultrasonic-based technique, capable of detecting the footprint of metallic containers or compartments concealed within the metallic structure of the inspected cargo, has been proposed. The system consists of an array of acoustic transceivers that is attached to the metallic structure-under-inspection, creating a guided acoustic Lamb wave. Reflections due to discontinuities are detected in the images, provided by an imaging algorithm. Taking into consideration that the majority of those images are sparse, this contribution analyzes the application of Compressed Sensing (CS techniques in order to reduce the amount of measurements needed, thus achieving faster scanning, without compromising the detection capabilities of the system. A parametric study of the image quality, as a function of the samples needed in spatial and frequency domains, is presented, as well as the dependence on the sampling pattern. For this purpose, realistic cargo inspection scenarios have been simulated.

  4. Compressed Sensing Techniques Applied to Ultrasonic Imaging of Cargo Containers. (United States)

    López, Yuri Álvarez; Lorenzo, José Ángel Martínez


    One of the key issues in the fight against the smuggling of goods has been the development of scanners for cargo inspection. X-ray-based radiographic system scanners are the most developed sensing modality. However, they are costly and use bulky sources that emit hazardous, ionizing radiation. Aiming to improve the probability of threat detection, an ultrasonic-based technique, capable of detecting the footprint of metallic containers or compartments concealed within the metallic structure of the inspected cargo, has been proposed. The system consists of an array of acoustic transceivers that is attached to the metallic structure-under-inspection, creating a guided acoustic Lamb wave. Reflections due to discontinuities are detected in the images, provided by an imaging algorithm. Taking into consideration that the majority of those images are sparse, this contribution analyzes the application of Compressed Sensing (CS) techniques in order to reduce the amount of measurements needed, thus achieving faster scanning, without compromising the detection capabilities of the system. A parametric study of the image quality, as a function of the samples needed in spatial and frequency domains, is presented, as well as the dependence on the sampling pattern. For this purpose, realistic cargo inspection scenarios have been simulated.

  5. A Novel Multilayered RFID Tagged Cargo Integrity Assurance Scheme. (United States)

    Yang, Ming Hour; Luo, Jia Ning; Lu, Shao Yong


    To minimize cargo theft during transport, mobile radio frequency identification (RFID) grouping proof methods are generally employed to ensure the integrity of entire cargo loads. However, conventional grouping proofs cannot simultaneously generate grouping proofs for a specific group of RFID tags. The most serious problem of these methods is that nonexistent tags are included in the grouping proofs because of the considerable amount of time it takes to scan a high number of tags. Thus, applying grouping proof methods in the current logistics industry is difficult. To solve this problem, this paper proposes a method for generating multilayered offline grouping proofs. The proposed method provides tag anonymity; moreover, resolving disputes between recipients and transporters over the integrity of cargo deliveries can be expedited by generating grouping proofs and automatically authenticating the consistency between the receipt proof and pick proof. The proposed method can also protect against replay attacks, multi-session attacks, and concurrency attacks. Finally, experimental results verify that, compared with other methods for generating grouping proofs, the proposed method can efficiently generate offline grouping proofs involving several parties in a supply chain using mobile RFID.

  6. Handling of bulk solids theory and practice

    CERN Document Server

    Shamlou, P A


    Handling of Bulk Solids provides a comprehensive discussion of the field of solids flow and handling in the process industries. Presentation of the subject follows classical lines of separate discussions for each topic, so each chapter is self-contained and can be read on its own. Topics discussed include bulk solids flow and handling properties; pressure profiles in bulk solids storage vessels; the design of storage silos for reliable discharge of bulk materials; gravity flow of particulate materials from storage vessels; pneumatic transportation of bulk solids; and the hazards of solid-mater

  7. National Security Science and Technology Initiative: Air Cargo Screening

    Energy Technology Data Exchange (ETDEWEB)

    Bingham, Philip R [ORNL; White, Tim [Pacific Northwest National Laboratory (PNNL); Cespedes, Ernesto [Idaho National Laboratory (INL); Bowerman, Biays [Brookhaven National Laboratory (BNL); Bush, John [Battelle


    The non-intrusive inspection (NII) of consolidated air cargo carried on commercial passenger aircraft continues to be a technically challenging, high-priority requirement of the Department of Homeland Security's Science and Technology Directorate (DHS S&T), the Transportation Security Agency and the Federal Aviation Administration. The goal of deploying a screening system that can reliably and cost-effectively detect explosive threats in consolidated cargo without adversely affecting the flow of commerce will require significant technical advances that will take years to develop. To address this critical National Security need, the Battelle Memorial Institute (Battelle), under a Cooperative Research and Development Agreement (CRADA) with four of its associated US Department of Energy (DOE) National Laboratories (Oak Ridge, Pacific Northwest, Idaho, and Brookhaven), conducted a research and development initiative focused on identifying, evaluating, and integrating technologies for screening consolidated air cargo for the presence of explosive threats. Battelle invested $8.5M of internal research and development funds during fiscal years 2007 through 2009. The primary results of this effort are described in this document and can be summarized as follows: (1) Completed a gap analysis that identified threat signatures and observables, candidate technologies for detection, their current state of development, and provided recommendations for improvements to meet air cargo screening requirements. (2) Defined a Commodity/Threat/Detection matrix that focuses modeling and experimental efforts, identifies technology gaps and game-changing opportunities, and provides a means of summarizing current and emerging capabilities. (3) Defined key properties (e.g., elemental composition, average density, effective atomic weight) for basic commodity and explosive benchmarks, developed virtual models of the physical distributions (pallets) of three commodity types and three

  8. Grounded or submerged bulk carrier: the potential for leaching of coal trace elements to seawater. (United States)

    Lucas, Steven Andrew; Planner, John


    This study investigates the potential for leaching of coal trace elements to seawater from a grounded bulk carrier. The coal type and ecological scenario was based on the grounding of the "Shen Neng" (April 2010) at Douglas Shoal located within the Great Barrier Reef (Queensland, Australia). The area is of high ecological value and the Queensland Water Quality Guidelines (2009) provided threshold limits to interpret potential impacts. Coal contains many trace elements that are of major and moderate concern to human health and the environment although many of these concerns are only realised when coal is combusted. However, "unburnt" coal contains trace elements that may be leached to natural waterways and few studies have investigated the potential ecological impact of such an occurrence. For example, coal maritime transport has increased by almost 35% over the last five reported years (Jaffrennou et al., 2007) and as a result there is an increased inherent risk of bulk carrier accidents. Upon grounding or becoming submerged, coal within a bulk carrier may become saturated with seawater and potentially leach trace elements to the environment and impact on water quality and ecological resilience. The worst case scenario is the breakup of a bulk carrier and dispersal of cargo to the seafloor. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  9. How molecular motors are arranged on a cargo is important for vesicular transport.

    Directory of Open Access Journals (Sweden)

    Robert P Erickson


    Full Text Available The spatial organization of the cell depends upon intracellular trafficking of cargos hauled along microtubules and actin filaments by the molecular motor proteins kinesin, dynein, and myosin. Although much is known about how single motors function, there is significant evidence that cargos in vivo are carried by multiple motors. While some aspects of multiple motor function have received attention, how the cargo itself--and motor organization on the cargo--affects transport has not been considered. To address this, we have developed a three-dimensional Monte Carlo simulation of motors transporting a spherical cargo, subject to thermal fluctuations that produce both rotational and translational diffusion. We found that these fluctuations could exert a load on the motor(s, significantly decreasing the mean travel distance and velocity of large cargos, especially at large viscosities. In addition, the presence of the cargo could dramatically help the motor to bind productively to the microtubule: the relatively slow translational and rotational diffusion of moderately sized cargos gave the motors ample opportunity to bind to a microtubule before the motor/cargo ensemble diffuses out of range of that microtubule. For rapidly diffusing cargos, the probability of their binding to a microtubule was high if there were nearby microtubules that they could easily reach by translational diffusion. Our simulations found that one reason why motors may be approximately 100 nm long is to improve their 'on' rates when attached to comparably sized cargos. Finally, our results suggested that to efficiently regulate the number of active motors, motors should be clustered together rather than spread randomly over the surface of the cargo. While our simulation uses the specific parameters for kinesin, these effects result from generic properties of the motors, cargos, and filaments, so they should apply to other motors as well.

  10. Increase of transport-logistic servicing efficiency of Sverdlovsk region’s agroindustrial complex (on the example of grain cargoes transportation

    Directory of Open Access Journals (Sweden)

    Mikhail Borisovich Petrov


    Full Text Available In this paper, the features of Sverdlovsk region to ensure grain products are reviewed. The dependence of the agricultural sector and the conditions of its transport and logistics are substantiated. It is proven that transport and logistics services have the greatest impact not on harvest and on its processing and storage. The choice of transport and logistics service strategy for enterprises of agriculture depends on productivity, prices for grain and its products and the financial condition of the producer. From the calculations made in the paper it is visible that rail transport has a significant — more than double — advantage over the automobile transport on unit costs for carriage in bulk grain cargo, but, for some reason, road transport is beginning to occupy an increasing share in the carriage of grain cargoes. Based on comparative analysis of costs to import grain cargo using various transport modes, recommendations for improvement of transport and logistics infrastructure are made, as well as measures for improving the payments system between producers, processors and transporters are suggested.

  11. Photonuclear-based Detection of Nuclear Smuggling in Cargo Containers (United States)

    Jones, J. L.; Haskell, K. J.; Hoggan, J. M.; Norman, D. R.; Yoon, W. Y.


    The Idaho National Engineering and Environmental Laboratory (INEEL) and the Los Alamos National Laboratory (LANL) have performed experiments in La Honda, California and at the Idaho Accelerator Center in Pocatello, Idaho to assess and develop a photonuclear-based detection system for shielded nuclear materials in cargo containers. The detection system, measuring photonuclear-related neutron emissions, is planned for integration with the ARACOR Eagle Cargo Container Inspection System (Sunnyvale, CA). The Eagle Inspection system uses a nominal 6-MeV electron accelerator and operates with safe radiation exposure limits to both container stowaways and to its operators. The INEEL has fabricated custom-built, helium-3-based, neutron detectors for this inspection application and is performing an experimental application assessment. Because the Eagle Inspection system could not be moved to LANL where special nuclear material was available, the response of the Eagle had to be determined indirectly so as to support the development and testing of the detection system. Experiments in California have successfully matched the delayed neutron emission performance of the ARACOR Eagle with that of the transportable INEEL electron accelerator (i.e., the Varitron) and are reported here. A demonstration test is planned at LANL using the Varitron and shielded special nuclear materials within a cargo container. Detector results are providing very useful information regarding the challenges of delayed neutron counting near the photofission threshold energy of 5.5 - 6.0 MeV, are identifying the possible utilization of prompt neutron emissions to allow enhanced signal-to-noise measurements, and are showing the overall benefits of using higher electron beam energies.

  12. X-ray scan detection for cargo integrity (United States)

    Valencia, Juan; Miller, Steve


    The increase of terrorism and its global impact has made the determination of the contents of cargo containers a necessity. Existing technology allows non-intrusive inspections to determine the contents of a container rapidly and accurately. However, some cargo shipments are exempt from such inspections. Hence, there is a need for a technology that enables rapid and accurate means of detecting whether such containers were non-intrusively inspected. Non-intrusive inspections are most commonly performed utilizing high powered X-ray equipment. The challenge is creating a device that can detect short duration X-ray scans while maintaining a portable, battery powered, low cost, and easy to use platform. The Pacific Northwest National Laboratory (PNNL) has developed a methodology and prototype device focused on this challenge. The prototype, developed by PNNL, is a battery powered electronic device that continuously measures its X-ray and Gamma exposure, calculates the dose equivalent rate, and makes a determination of whether the device has been exposed to the amount of radiation experienced during an X-ray inspection. Once an inspection is detected, the device will record a timestamp of the event and relay the information to authorized personnel via a visual alert, USB connection, and/or wireless communication. The results of this research demonstrate that PNNL's prototype device can be effective at determining whether a container was scanned by X-ray equipment typically used for cargo container inspections. This paper focuses on laboratory measurements and test results acquired with the PNNL prototype device using several X-ray radiation levels.

  13. Massively Parallel Delivery of Large-Sized Cargo into Mammalian Cells with Light Pulses


    Wu, Yi-Chien; Wu, Ting-Hsiang; Clemens, Daniel L.; Lee, Bai-Yu; Wen, Ximiao; Horwitz, Marcus A.; Teitell, Michael A.; Chiou, Pei-Yu


    We report a high-throughput platform for delivering large cargo into 100,000 cells in 1 min. An array of micro-cavitation bubbles explode in response to laser pulsing, forming pores in adjacent cell membranes, and immediately thereafter, pressurized flows drive slow diffusing cargo through these pores into cells. The platform delivers large cargo including bacteria, enzymes, antibodies, and nanoparticles into diverse cell types with high efficiency and cell viability. We used this platform to...

  14. A Framework for Analysis of Security Measures Within On-airport Cargo Facilities


    Rountree, Carla; Demetsky, Michael J.


    The terrorist attacks of September 11, 2001 displayed the shortcomings of aviation security in the United States. Most of the attention on aviation security since that time has focused on airline passengers, their luggage, and their carry-on items, leaving air cargo security on the back burner. The lack of security screening and screening guidelines of cargo traveling by both passenger and all-cargo aircraft is the driving purpose behind this research project: the development of a framework t...

  15. Optimization of the imported air express cargo distribution problem

    Directory of Open Access Journals (Sweden)

    Hwang, T.L.


    Full Text Available This study examines the delivering network of imported air express cargo as an integrated multi-depot vehicle routing problem. Integrated multi-depot vehicle routing problem attempts to decide which service centers should be used and how much freight should be unloaded in each service center. The role of an exchange point which is allowing the delivery vans and shuttles to exchange imported and exported goods is also addressed. Test results demonstrate the feasibility of the four models so these are highly promising for use in a diverse array of applications, such as in home delivery and reverse logistics.

  16. Cargo binding activates myosin VIIA motor function in cells


    Sakai, Tsuyoshi; Umeki, Nobuhisa; Ikebe, Reiko; Ikebe, Mitsuo


    Myosin VIIA, thought to be involved in human auditory function, is a gene responsible for human Usher syndrome type 1B, which causes hearing and visual loss. Recent studies have suggested that it can move processively if it forms a dimer. Nevertheless, it exists as a monomer in vitro, unlike the well-known two-headed processive myosin Va. Here we studied the molecular mechanism, which is currently unknown, of activating myosin VIIA as a cargo-transporting motor. Human myosin VIIA was present ...

  17. Analytical solution of the problem of acceleration of cargo by a bridge crane with constant acceleration at elimination of swings of a cargo rope (United States)

    Korytov, M. S.; Shcherbakov, V. S.; Titenko, V. V.


    Limitation of the swing of the bridge crane cargo rope is a matter of urgency, as it can significantly improve the efficiency and safety of the work performed. In order to completely dampen the pendulum swing after the break-up of a bridge or a bridge-crane freight cart to maximum speed, it is necessary, in the normal repulsion control of the electric motor, to split the process of dispersion into a minimum of three gaps. For a dynamic system of swinging of a bridge crane on a flexible cable hanger in a separate vertical plane, an analytical solution was obtained to determine the temporal dependence of the cargo rope angle relative to the gravitational vertical when the cargo suspension point moves with constant acceleration. The resulting analytical dependence of the cargo rope angle and its first derivative can break the process of dispersing the cargo suspension point into three stages of dispersal and braking with various accelerations and enter maximum speed of movement of the cargo suspension point. In doing so, the condition of eliminating the swings of the cargo rope relative to the gravitational vertical is fulfilled. Provides examples of the maximum speed output constraints-to-time when removing the rope swing.

  18. Coupling brane fields to bulk supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Parameswaran, Susha L. [Uppsala Univ. (Sweden). Theoretical Physics; Schmidt, Jonas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)


    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  19. Aviation security cargo inspection queuing simulation model for material flow and accountability (United States)

    Allgood, Glenn O.; Olama, Mohammed M.; Rose, Terri A.; Brumback, Daryl


    Beginning in 2010, the U.S. will require that all cargo loaded in passenger aircraft be inspected. This will require more efficient processing of cargo and will have a significant impact on the inspection protocols and business practices of government agencies and the airlines. In this paper, we develop an aviation security cargo inspection queuing simulation model for material flow and accountability that will allow cargo managers to conduct impact studies of current and proposed business practices as they relate to inspection procedures, material flow, and accountability.

  20. Safety of Oversize Cargo in Ports and in the Sea Transport

    Directory of Open Access Journals (Sweden)

    Miroslaw Chmielinski


    Full Text Available Author of the paper analyzes problems related to the safety of the oversize cargo in ports and in the sea transport. Various modes of transport are used to carry oversized units that often include maritime transport. Transport of oversized cargo includes non-standard large and heavy pieces of cargo, such as electric transformers, reactor vessels, wind turbines, airplane fuselage or nuclear power plant components. The above paper is based on results of research oversized cargo in the Elpo Service Company and Pol-Mare Ltd. forwarding consulting agency.

  1. Functional architecture of the retromer cargo-recognition complex (United States)

    Hierro, Aitor; Rojas, Adriana L.; Rojas, Raul; Murthy, Namita; Effantin, Grégory; Kajava, Andrey V.; Steven, Alasdair C.; Bonifacino, Juan S.; Hurley, James H.


    The retromer complex 1, 2 is required for the sorting of acid hydrolases to lysosomes 3-7, transcytosis of the polymeric Ig receptor 8, Wnt gradient formation 9, 10, iron transporter recycling 11, and processing of the amyloid precursor protein 12. Human retromer consists of two smaller complexes, the cargo recognition Vps26:Vps29:Vps35 heterotrimer, and a membrane-targeting heterodimer or homodimer of SNX1 and/or SNX2 13. The crystal structure of a Vps29:Vps35 subcomplex shows how the metallophosphoesterase-fold subunit Vps29 14, 15 acts as a scaffold for the C-terminal half of Vps35. Vps35 forms a horseshoe-shaped right-handed α-helical solenoid whose concave face completely covers the metal-binding site of Vps29 and whose convex face exposes a series of hydrophobic interhelical grooves. Electron microscopy shows that the intact Vps26:Vps29:Vps35 complex is a stick-shaped, somewhat flexible, structure, ∼ 21 nm long. A hybrid structural model derived from crystal structures, electron microscopy, interaction studies, and bioinformatics shows that the α-solenoid fold extends the full length of Vps35, and that Vps26 is bound at the opposite end from Vps29. This extended structure presents multiple binding sites for the SNX complex and receptor cargo, and appears capable of flexing to conform to curved vesicular membranes. PMID:17891154

  2. Achieving integrated convoys: cargo unmanned ground vehicle development and experimentation (United States)

    Zych, Noah; Silver, David; Stager, David; Green, Colin; Pilarski, Thomas; Fischer, Jacob


    The Cargo UGV project was initiated in 2010 with the aim of developing and experimenting with advanced autonomous vehicles capable of being integrated unobtrusively into manned logistics convoys. The intent was to validate two hypotheses in complex, operationally representative environments: first, that unmanned tactical wheeled vehicles provide a force protection advantage by creating standoff distance to warfighters during ambushes or improvised explosive device attacks; and second, that these UGVs serve as force multipliers by enabling a single operator to control multiple unmanned assets. To assess whether current state-of-the-art autonomous vehicle technology was sufficiently capable to permit resupply missions to be executed with decreased risk and reduced manpower, and to assess the effect of UGVs on customary convoy tactics, the Marine Corps Warfighting Laboratory and the Joint Ground Robotics Enterprise sponsored Oshkosh Defense and the National Robotics Engineering Center to equip two standard Marine Corps cargo trucks for autonomous operation. This paper details the system architecture, hardware implementation, and software modules developed to meet the vehicle control, perception, and planner requirements compelled by this application. Additionally, the design of a custom human machine interface and an accompanying training program are described, as is the creation of a realistic convoy simulation environment for rapid system development. Finally, results are conveyed from a warfighter experiment in which the effectiveness of the training program for novice operators was assessed, and the impact of the UGVs on convoy operations was observed in a variety of scenarios via direct comparison to a fully manned convoy.

  3. Cargo Loading and Unloading Efficiency Analysis in Multimodal Transport

    Directory of Open Access Journals (Sweden)

    Rafał Burdzik


    Full Text Available The paper presents assessment of the impact of the processes handling efficiency on the transport process based on research done in the real object, using same technologies and material handling equipment. The aim of the paper was to confirm importance of loading and unloading processes of palletized cargo as an initial and final link of multimodal transport by developing methods’ proposal for monitoring and assessing the effectiveness of cargo operations as well as development of measures and comparison estimators. The analysis of the manipulation operations’ duration throughout the transport process is based on the percentile rates of manipulation and carriage in total transport process duration and the percentage of manipulating time in the duration of the carriage. These indicators and examined loading and unloading times, are the basis for the development of scheduling algorithms for optimizing transport processes on the scale of the whole transport chain. This data is also a helpful input to support strategic decisions on the allocation of financial resources for the development of infrastructure and terminal equipment, warehouses and other facilities.

  4. Vehicle and cargo container inspection system for drugs (United States)

    Verbinski, Victor V.; Orphan, Victor J.


    A vehicle and cargo container inspection system has been developed which uses gamma-ray radiography to produce digital images useful for detection of drugs and other contraband. The system is comprised of a 1 Ci Cs137 gamma-ray source collimated into a fan beam which is aligned with a linear array of NaI gamma-ray detectors located on the opposite side of the container. The NaI detectors are operated in the pulse-counting mode. A digital image of the vehicle or container is obtained by moving the aligned source and detector array relative to the object. Systems have been demonstrated in which the object is stationary (source and detector array move on parallel tracks) and in which the object moves past a stationary source and detector array. Scanning speeds of ˜30 cm/s with a pixel size (at the object) of ˜1 cm have been achieved. Faster scanning speeds of ˜2 m/s have been demonstrated on railcars with more modest spatial resolution (4 cm pixels). Digital radiographic images are generated from the detector count rates. These images, recorded on a PC-based data acquisition and display system, are shown from several applications: 1) inspection of trucks and containers at a border crossing, 2) inspection of railcars at a border crossing, 3) inspection of outbound cargo containers for stolen automobiles, and 4) inspection of trucks and cars for terrorist bombs.

  5. Placenta-derived extracellular vesicles: their cargo and possible functions. (United States)

    Familari, Mary; Cronqvist, Tina; Masoumi, Zahra; Hansson, Stefan R


    The literature on extracellular vesicles consists of rapidly expanding and often contradictory information. In this paper we attempt to review what is currently known regarding extracellular vesicles released specifically from human placental syncytiotrophoblast cells with a focus on the common but complex pregnancy-associated syndrome pre-eclampsia, where the level of syncytiotrophoblast extracellular vesicle release is significantly increased. We review common methods for syncytiotrophoblast extracellular vesicle derivation and isolation and we discuss the cargo of syncytiotrophoblast extracellular vesicles including proteins, RNA and lipids and their possible functions. A meta-analysis of available trophoblast-derived extracellular vesicle proteomic datasets revealed only three proteins in common: albumin, fibronectin-1 and plasminogen activator inhibitor-1, suggesting some variability in vesicle cargo, most likely reflecting stage and cell type of origin. We discuss the possible sources of variability that may have led to the low number of common markers, which has led us to speculate that markers and density in common use may not be strict criteria for identifying and isolating placenta-derived exosomes.

  6. Spatial partitioning of secretory cargo from Golgi resident proteins in live cells

    Directory of Open Access Journals (Sweden)

    White Jamie


    Full Text Available Abstract Background To maintain organelle integrity, resident proteins must segregate from itinerant cargo during secretory transport. However, Golgi resident enzymes must have intimate access to secretory cargo in order to carry out glycosylation reactions. The amount of cargo and associated membrane may be significant compared to the amount of Golgi membrane and resident protein, but upon Golgi exit, cargo and resident are efficiently sorted. How this occurs in live cells is not known. Results We observed partitioning of the fluorescent Golgi resident T2-CFP and fluorescent cargo proteins VSVG3-YFP or VSVG3-SP-YFP upon Golgi exit after a synchronous pulse of cargo was released from the ER. Golgi elements remained stable in overall size, shape and relative position as cargo emptied. Cargo segregated from resident rapidly by blebbing into micron-sized domains that contained little or no detectable resident protein and that appeared to be continuous with the parent Golgi element. Post-Golgi transport carriers (TCs exited repeatedly from these domains. Alternatively, entire cargo domains exited Golgi elements, forming large TCs that fused directly with the plasma membrane. However, domain formation did not appear to be an absolute prerequisite for TC exit, since TCs also exited directly from Golgi elements in the absence of large domains. Quantitative cargo-specific photobleaching experiments revealed transfer of cargo between Golgi regions, but no discrete intra-Golgi TCs were observed. Conclusions Our results establish domain formation via rapid lateral partitioning as a general cellular strategy for segregating different transmembrane proteins along the secretory pathway and provide a framework for consideration of molecular mechanisms of secretory transport.

  7. Effect of fuel concentration on cargo transport by a team of Kinesin motors (United States)

    Takshak, Anjneya; Mishra, Nirvantosh; Kulkarni, Aditi; Kunwar, Ambarish


    Eukaryotic cells employ specialized proteins called molecular motors for transporting organelles and vesicles from one location to another in a regulated and directed manner. These molecular motors often work collectively in a team while transporting cargos. Molecular motors use cytoplasmic ATP as fuel, which is hydrolyzed to generate mechanical force. While the effect of ATP concentration on cargo transport by single Kinesin motor function is well understood, it is still unexplored, both theoretically and experimentally, how ATP concentration would affect cargo transport by a team of Kinesin motors. For instance, how does fuel concentration affect the travel distances and travel velocities of cargo? How cooperativity of Kinesin motors engaged on a cargo is affected by ATP concentration? To answer these questions, here we develop mechano-chemical models of cargo transport by a team of Kinesin motors. To develop these models we use experimentally-constrained mechano-chemical model of a single Kinesin motor as well as earlier developed mean-field and stochastic models of load sharing for cargo transport. Thus, our new models for cargo transport by a team of Kinesin motors include fuel concentration explicitly, which was not considered in earlier models. We make several interesting predictions which can be tested experimentally. For instance, the travel distances of cargos are very large at limited ATP concentrations in spite of very small travel velocity. Velocities of cargos driven by multiple Kinesin have a Michaelis-Menten dependence on ATP concentration. Similarly, cooperativity among the engaged Kinesin motors on the cargo shows a Michaelis-Menten type dependence, which attains a maximum value near physiological ATP concentrations. Our new results can be potentially useful in controlling artificial nano-molecular shuttles precisely for targeted delivery in various nano-technological applications.

  8. 27 CFR 20.191 - Bulk articles. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk articles. 20.191... Users of Specially Denatured Spirits Operations by Users § 20.191 Bulk articles. Users who convey articles in containers exceeding one gallon may provide the recipient with a photocopy of subpart G of this...

  9. Characteristics of future air cargo demand and impact on aircraft development: A report on the Cargo/Logistic Airlift Systems Study (CLASS) project (United States)

    Whitehead, A. H., Jr.


    Current domestic and international air cargo operations are studied and the characteristics of 1990 air cargo demand are postulated from surveys conducted at airports and with shippers, consignees, and freight forwarders as well as air, land, and ocean carriers. Simulation and route optimization programs are exercised to evaluate advanced aircraft concepts. The results show that proposed changes in the infrastructure and improved cargo loading efficiencies are as important enhancing the prospects of air cargo growth as is the advent of advanced freighter aircraft. Potential reductions in aircraft direct operating costs are estimated and related to future total revenue. Service and cost elasticities are established and utilized to estimate future potential tariff reductions that may be realized through direct and indirect operating cost reductions and economies of scale.

  10. Changing Concentration Ratios and Geographical Patterns of Bulk Ports: The Case of the Korean West Coast

    Directory of Open Access Journals (Sweden)

    Taehwee Lee


    Full Text Available Contrary to liner shipping, common shipping network patterns are difficult to organize in tramp shipping as origin and destination ports are irregular and they may change based on shippers’ demands. Unlike liner shipping whereas the choice of ports is strongly related to their geographical locations among other factors and a topic of much research in the contemporary literature, the geographical issues related to bulk ports are an interesting yet currently under-researched topic. For this reason, this study aims to analyze the concentration ratios of bulk ports to reveal geographical patterns, using the case of bulk ports along the west coast of Korea including, Incheon Port (ICP, Pyeongtaek-Dangjin Port (PDP, and Gunsan Port (GSP. To examine and shed more light to the above mentioned research issue, this paper adopts a series of methods, such as Hirshmann-Herfindahl Index (HHI, Location Quotients (LQ, and Shift Effects (SE. Results from the HHI analysis, indicated that de-concentration has been gradually rising because of a considerable overlapping of ports’ functions. Meanwhile, the LQs’ confirmed this result. Finally, the SE’ results effectively showed that a substantial shifting of cargo had occurred among the ports.

  11. 49 CFR 173.33 - Hazardous materials in cargo tank motor vehicles. (United States)


    ... material lading would have a dangerous reaction with the hazardous material. (2) A cargo tank may not be... severely corrode or react with the tank material at any concentration and temperature that will exist...) To prevent cargo tank rupture in a loading or unloading accident, the loading or unloading rate used...

  12. 78 FR 50134 - Altus Pharmaceuticals, Inc., Blackhawk Capital Group BDC, Inc., Cargo Connection Logistics... (United States)


    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Altus Pharmaceuticals, Inc., Blackhawk Capital Group BDC, Inc., Cargo Connection Logistics Holding... securities of Cargo Connection Logistics Holding, Inc. because it has not filed any periodic reports since...

  13. 14 CFR 121.198 - Cargo service airplanes: Increased zero fuel and landing weights. (United States)


    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Cargo service airplanes: Increased zero... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.198 Cargo service airplanes: Increased zero fuel and landing weights...

  14. 19 CFR 192.14 - Electronic information for outward cargo required in advance of departure. (United States)


    .... Specifically, to effect the advance electronic transmission of the required cargo information to CBP, the USPPI... 19 Customs Duties 2 2010-04-01 2010-04-01 false Electronic information for outward cargo required in advance of departure. 192.14 Section 192.14 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION...

  15. CargoVibes: human response to vibration due to freight rail traffic

    NARCIS (Netherlands)

    Waddington, D.; Woodcock, J.; Smith, M.G.; Janssen, S.A.; Persson Waye, K.


    The aim of this paper is to present an overview of the research concerning human response to vibration conducted in the EU FP7 CargoVibes project. The European Union-funded project CargoVibes involved 10 partners from 8 nations and ran from April 2011 to April 2014. The project was concerned with

  16. 78 FR 58986 - Dry Cargo Residue Discharges in the Great Lakes (United States)


    ... SECURITY Coast Guard 33 CFR Part 151 RIN 1625-AA89 Dry Cargo Residue Discharges in the Great Lakes AGENCY... the Great Lakes. The Coast Guard requests public comment on the FEIS. DATES: Comments and related... associated with a proposed final rule to regulate discharges of dry cargo residue in the Great Lakes. In...

  17. 49 CFR 180.407 - Requirements for test and inspection of specification cargo tanks. (United States)


    ... except MC 338 September 1, 1991 1 year. Pressure Test: (Hydrostatic or pneumatic) (See Notes 2 and 3) All... or pneumatic pressure-test of the cargo tank. (d) External visual inspection and testing. The... appurtenances and structural attachments on the cargo tank including, but not limited to, suspension system...

  18. Molecular sleds comprising a positively -charged amino acid sequence and a molecular cargo and uses thereof

    NARCIS (Netherlands)



    The present invention relates to compositions which may comprise a molecular sled linked to cargo and uses thereof. In particular, the present invention relates to a non-naturally occurring or engineered composition which may comprise a molecular sled, linkers and a molecular cargo connected to the

  19. 46 CFR 32.60-15 - Segregation of cargo; Grade E-TB/ALL. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Segregation of cargo; Grade E-TB/ALL. 32.60-15 Section 32.60-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT... § 32.60-15 Segregation of cargo; Grade E—TB/ALL. (a) General. The galleys, living quarters, navigation...

  20. 19 CFR 4.85 - Vessels with residue cargo for domestic ports. (United States)


    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Vessels with residue cargo for domestic ports. 4...; DEPARTMENT OF THE TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Coastwise Procedure § 4.85 Vessels with residue cargo for domestic ports. (a) Any foreign vessel or documented vessel with a registry or, where...

  1. Neutron interrogation system using high gamma ray signature to detect contraband special nuclear materials in cargo (United States)

    Slaughter, Dennis R [Oakland, CA; Pohl, Bertram A [Berkeley, CA; Dougan, Arden D [San Ramon, CA; Bernstein, Adam [Palo Alto, CA; Prussin, Stanley G [Kensington, CA; Norman, Eric B [Oakland, CA


    A system for inspecting cargo for the presence of special nuclear material. The cargo is irradiated with neutrons. The neutrons produce fission products in the special nuclear material which generate gamma rays. The gamma rays are detecting indicating the presence of the special nuclear material.

  2. 49 CFR 175.26 - Notification at cargo facilities of hazardous materials requirements. (United States)


    ... following information: (1) Cargo containing hazardous materials (dangerous goods) for transportation by... U.S.C. 5124). (3) Hazardous materials (dangerous goods) include explosives, compressed gases... 49 Transportation 2 2010-10-01 2010-10-01 false Notification at cargo facilities of hazardous...

  3. 23 CFR 658.23 - LCV freeze; cargo-carrying unit freeze. (United States)


    ... 23 Highways 1 2010-04-01 2010-04-01 false LCV freeze; cargo-carrying unit freeze. 658.23 Section... OPERATIONS TRUCK SIZE AND WEIGHT, ROUTE DESIGNATIONS-LENGTH, WIDTH AND WEIGHT LIMITATIONS § 658.23 LCV freeze; cargo-carrying unit freeze. (a)(1) Except as otherwise provided in this section and except for tow...

  4. 46 CFR 308.551 - War risk insurance clearing agency agreement for cargo, Form MA-321. (United States)


    ... 46 Shipping 8 2010-10-01 2010-10-01 false War risk insurance clearing agency agreement for cargo... EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iv-General § 308.551 War risk insurance...-321, shall be executed by the Maritime Administrator and domestic insurance companies, or groups of...

  5. 33 CFR 105.295 - Additional requirements-Certain Dangerous Cargo (CDC) facilities. (United States)


    ... Dangerous Cargo (CDC) facilities. 105.295 Section 105.295 Navigation and Navigable Waters COAST GUARD... Requirements § 105.295 Additional requirements-Certain Dangerous Cargo (CDC) facilities. (a) At all MARSEC Levels, owners or operators of CDC facilities must ensure the implementation of the following security...


    Kelić, Katarina; Matić, Sanja; Marović, Danijela; Klarić, Eva; Tarle, Zrinka


    The aim of the study was to determine microhardness of high- and low-viscosity bulk-fill composite resins and compare it with conventional composite materials. Four materials of high-viscosity were tested, including three bulk-fills: QuiXfi l (QF), x-tra fi l (XTF) and Tetric EvoCeram Bulk Fill (TEBCF), while nanohybrid composite GrandioSO (GSO) served as control. The other four were low-viscosity composites, three bulk-fill materials: Smart Dentin Replacement (SDR), Venus Bulk Fill (VBF) and x-tra base (XB), and conventional control material X-Flow (XF). Composite samples (n=5) were polymerized for 20 s with Bluephase G2 curing unit. Vickers hardness was used to determine microhardness of each material at the surface, and at 2-mm and 4-mm depth. GSO on average recorded significantly higher microhardness values than bulk-fill materials (pcomposite XF revealed similar microhardness values as SDR, but significantly lower than XB (pmaterials was lower than microhardness of the conventional composite material (GSO). Surface microhardness of low-viscosity materials was generally even lower. The microhardness of all tested materials at 4 mm was not different from their surface values. However, additional capping layer was a necessity for low-viscosity bulk-fill materials due to their low microhardness.

  7. NASA's approach to commercial cargo and crew transportation (United States)

    Stone, Dennis; Lindenmoyer, Alan; French, George; Musk, Elon; Gump, David; Kathuria, Chirinjeev; Miller, Charles; Sirangelo, Mark; Pickens, Tom


    To stimulate the commercial space industry and potentially serve the logistics needs of the International Space Station (ISS) in the post-Space Shuttle era, the National Aeronautics and Space Administration (NASA) in 2006 began the Commercial Orbital Transportation Services (COTS) initiative. NASA entered into agreements with two U.S. firms, Rocketplane Kistler and Space Exploration Technologies to share up to 485,000,000 USD to demonstrate cargo transportation services to and from Low Earth orbit (LEO), with an option for additional funds to demonstrate human transportation services. Subsequently, NASA also entered into unfunded agreements with five companies to develop innovative space transportation capabilities. This paper reviews this unique initiative, describes the concepts of these seven companies, and discusses the potential of this emerging industry to make LEO more accessible.

  8. ATHLETE: A Cargo-Handling Vehicle for Solar System Exploration (United States)

    Wilcox, Brian H.


    As part of the NASA Exploration Technology Development Program, the Jet Propulsion Laboratory is developing a vehicle called ATHLETE: the All-Terrain Hex-Limbed Extra-Terrestrial Explorer. Each vehicle is based on six wheels at the ends of six multi-degree-of-freedom limbs. Because each limb has enough degrees of freedom for use as a general-purpose leg, the wheels can be locked and used as feet to walk out of excessively soft or other extreme terrain. Since the vehicle has this alternative mode of traversing through or at least out of extreme terrain, the wheels and wheel actuators can be sized for nominal terrain. There are substantial mass savings in the wheel and wheel actuators associated with designing for nominal instead of extreme terrain. These mass savings are comparable-to or larger-than the extra mass associated with the articulated limbs. As a result, the entire mobility system, including wheels and limbs, can be about 25% lighter than a conventional mobility chassis. A side benefit of this approach is that each limb has sufficient degrees-of-freedom to use as a general-purpose manipulator (hence the name "limb" instead of "leg"). Our prototype ATHLETE vehicles have quick-disconnect tool adapters on the limbs that allow tools to be drawn out of a "tool belt" and maneuvered by the limb. A power-take-off from the wheel actuates the tools, so that they can take advantage of the 1+ horsepower motor in each wheel to enable drilling, gripping or other power-tool functions. Architectural studies have indicated that one useful role for ATHLETE in planetary (moon or Mars) exploration is to "walk" cargo off the payload deck of a lander and transport it across the surface. Recent architectural approaches are focused on the concept that the lander descent stage will use liquid hydrogen as a propellant. This is the highest performance chemical fuel, but it requires very large tanks. A natural geometry for the lander is to have a single throttleable rocket engine on

  9. 78 FR 63237 - Extension of the Air Cargo Advance Screening (ACAS) Pilot Program and Reopening of Application... (United States)


    ... SECURITY U.S. Customs and Border Protection Extension of the Air Cargo Advance Screening (ACAS) Pilot... air cargo environment. The notice provides a description of the ACAS pilot, sets forth eligibility... information for air cargo. The results of the ACAS pilot will help determine the relevant data elements, the...

  10. 19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international... (United States)


    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international traffic; repair components. (a)(1) Lift vans, cargo vans, shipping tanks, skids, pallets, caul...

  11. 46 CFR 35.35-60 - Transportation of other cargo or stores on tank barges-B/ALL. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Transportation of other cargo or stores on tank barges-B/ALL. 35.35-60 Section 35.35-60 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Cargo Handling § 35.35-60 Transportation of other cargo or stores on tank barges—B/ALL. (a) Tank...

  12. 46 CFR 35.35-55 - Transfer of other cargo or stores on tank vessels-TB/ALL. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Transfer of other cargo or stores on tank vessels-TB/ALL... OPERATIONS Cargo Handling § 35.35-55 Transfer of other cargo or stores on tank vessels—TB/ALL. (a) No packaged goods, freight, or ship's stores may be loaded or unloaded during the loading or unloading of...

  13. A brief overview of bulk metallic glasses

    National Research Council Canada - National Science Library

    Mingwei Chen


      The discovery of bulk metallic glasses (BMGs) has stimulated widespread research enthusiasm because of their technological promise for practical applications and scientific importance in understanding glass formation and glass phenomena...

  14. Boundary-bulk relation in topological orders (United States)

    Kong, Liang; Wen, Xiao-Gang; Zheng, Hao


    In this paper, we study the relation between an anomaly-free n + 1D topological order, which are often called n + 1D topological order in physics literature, and its nD gapped boundary phases. We argue that the n + 1D bulk anomaly-free topological order for a given nD gapped boundary phase is unique. This uniqueness defines the notion of the "bulk" for a given gapped boundary phase. In this paper, we show that the n + 1D "bulk" phase is given by the "center" of the nD boundary phase. In other words, the geometric notion of the "bulk" corresponds precisely to the algebraic notion of the "center". We achieve this by first introducing the notion of a morphism between two (potentially anomalous) topological orders of the same dimension, then proving that the notion of the "bulk" satisfies the same universal property as that of the "center" of an algebra in mathematics, i.e. "bulk" = center". The entire argument does not require us to know the precise mathematical description of a (potentially anomalous) topological order. This result leads to concrete physical predictions.

  15. Tackling the x-ray cargo inspection challenge using machine learning (United States)

    Jaccard, Nicolas; Rogers, Thomas W.; Morton, Edward J.; Griffin, Lewis D.


    The current infrastructure for non-intrusive inspection of cargo containers cannot accommodate exploding com-merce volumes and increasingly stringent regulations. There is a pressing need to develop methods to automate parts of the inspection workflow, enabling expert operators to focus on a manageable number of high-risk images. To tackle this challenge, we developed a modular framework for automated X-ray cargo image inspection. Employing state-of-the-art machine learning approaches, including deep learning, we demonstrate high performance for empty container verification and specific threat detection. This work constitutes a significant step towards the partial automation of X-ray cargo image inspection.

  16. Integration of bulk piezoelectric materials into microsystems (United States)

    Aktakka, Ethem Erkan

    Bulk piezoelectric ceramics, compared to deposited piezoelectric thin-films, provide greater electromechanical coupling and charge capacity, which are highly desirable in many MEMS applications. In this thesis, a technology platform is developed for wafer-level integration of bulk piezoelectric substrates on silicon, with a final film thickness of 5-100microm. The characterized processes include reliable low-temperature (200°C) AuIn diffusion bonding and parylene bonding of bulk-PZT on silicon, wafer-level lapping of bulk-PZT with high-uniformity (+/-0.5microm), and low-damage micro-machining of PZT films via dicing-saw patterning, laser ablation, and wet-etching. Preservation of ferroelectric and piezoelectric properties is confirmed with hysteresis and piezo-response measurements. The introduced technology offers higher material quality and unique advantages in fabrication flexibility over existing piezoelectric film deposition methods. In order to confirm the preserved bulk properties in the final film, diaphragm and cantilever beam actuators operating in the transverse-mode are designed, fabricated and tested. The diaphragm structure and electrode shapes/sizes are optimized for maximum deflection through finite-element simulations. During tests of fabricated devices, greater than 12microm PP displacement is obtained by actuation of a 1mm2 diaphragm at 111kHz with sleep-mode (simulated). Under lg vibration at 155Hz, a 70mF ultra-capacitor is charged from OV to 1.85V in 50 minutes.

  17. Development of superconductor bulk for superconductor bearing

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Joong; Jun, Byung Hyuk; Park, Soon Dong (and others)


    Current carrying capacity is one of the most important issues in the consideration of superconductor bulk materials for engineering applications. There are numerous applications of Y-Ba-Cu-O (YBCO) bulk superconductors e.g. magnetic levitation train, flywheel energy storage system, levitation transportation, lunar telescope, centrifugal device, magnetic shielding materials, bulk magnets etc. Accordingly, to obtain YBCO materials in the form of large, single crystals without weak-link problem is necessary. A top seeded melt growth (TSMG) process was used to fabricate single crystal YBCO bulk superconductors. The seeded and infiltration growth (IG) technique was also very promising method for the synthesis of large, single-grain YBCO bulk superconductors with good superconducting properties. 5 wt.% Ag doped Y211 green compacts were sintered at 900 .deg. C {approx} 1200 .deg.C and then a single crystal YBCO was fabricated by an infiltration method. A refinement and uniform distribution of the Y211 particles in the Y123 matrix were achieved by sintering the Ag-doped samples. This enhancement of the critical current density was ascribable to a fine dispersion of the Y211 particles, a low porosity and the presence of Ag particles. In addition, we have designed and manufactured large YBCO single domain with levitation force of 10-13 kg/cm{sup 2} using TSMG processing technique.

  18. The Lethal Cargo of Myxococcus xanthus Outer Membrane Vesicles

    Directory of Open Access Journals (Sweden)

    James E Berleman


    Full Text Available Myxococcus xanthus is a bacterial micro-predator known for hunting other microbes in a wolf pack-like manner. Outer membrane vesicles (OMVs are produced in large quantities by M. xanthus and have a highly organized structure in the extracellular milieu, sometimes occurring in chains that link neighboring cells within a biofilm. OMVs may be a vehicle for mediating wolf pack activity by delivering hydrolytic enzymes and antibiotics aimed at killing prey microbes. Here, both the protein and small molecule cargo of the OMV and membrane fractions of M. xanthus were characterized and compared. Our analysis indicates a number of proteins that are OMV-specific or OMV-enriched, including several with putative hydrolytic function. Secondary metabolite profiling of OMVs identifies 16 molecules, many associated with antibiotic activities. Several hydrolytic enzyme homologs were identified, including MXAN_3564 (mepA, an M36 protease homolog. Genetic disruption of mepA leads to a significant reduction in extracellular protease activity suggesting MepA is the long-predicted (yet to date unknown primary extracellular protease in M. xanthus.

  19. Underwater Photogrammetry and 3d Reconstruction of Marble Cargos Shipwreck (United States)

    Balletti, C.; Beltrame, C.; Costa, E.; Guerra, F.; Vernier, P.


    Nowadays archaeological and architectural surveys are based on the acquisition and processing of point clouds, allowing a high metric precision, essential prerequisite for a good documentation. Digital image processing and laser scanner have changed the archaeological survey campaign, from manual and direct survey to a digital one and, actually, multi-image photogrammetry is a good solution for the underwater archaeology. This technical documentation cannot operate alone, but it has to be supported by a topographical survey to georeference all the finds in the same reference system. In the last years the Ca' Foscari and IUAV University of Venice are conducting a research on integrated survey techniques to support underwater metric documentation. The paper will explain all the phases regarding the survey's design, images acquisition, topographic measure and the data processing of two Roman shipwrecks in south Sicily. The cargos of the shipwrecks are composed by huge marble blocks, but they are different for morphological characteristic of the sites, for the depth and for their distribution on the seabed. Photogrammetrical and topographical surveys were organized in two distinct methods, especially for the second one, due to the depth that have allowed an experimentation of GPS RTK's measurements on one shipwreck. Moreover, this kind of three-dimensional documentation is useful for educational and dissemination aspect, for the ease of understanding by wide public.

  20. Modal Testing of Seven Shuttle Cargo Elements for Space Station (United States)

    Kappus, Kathy O.; Driskill, Timothy C.; Parks, Russel A.; Patterson, Alan (Technical Monitor)


    From December 1996 to May 2001, the Modal and Control Dynamics Team at NASA's Marshall Space Flight Center (MSFC) conducted modal tests on seven large elements of the International Space Station. Each of these elements has been or will be launched as a Space Shuttle payload for transport to the International Space Station (ISS). Like other Shuttle payloads, modal testing of these elements was required for verification of the finite element models used in coupled loads analyses for launch and landing. The seven modal tests included three modules - Node, Laboratory, and Airlock, and four truss segments - P6, P3/P4, S1/P1, and P5. Each element was installed and tested in the Shuttle Payload Modal Test Bed at MSFC. This unique facility can accommodate any Shuttle cargo element for modal test qualification. Flexure assemblies were utilized at each Shuttle-to-payload interface to simulate a constrained boundary in the load carrying degrees of freedom. For each element, multiple-input, multiple-output burst random modal testing was the primary approach with controlled input sine sweeps for linearity assessments. The accelerometer channel counts ranged from 252 channels to 1251 channels. An overview of these tests, as well as some lessons learned, will be provided in this paper.

  1. Seipin regulates ER-lipid droplet contacts and cargo delivery. (United States)

    Salo, Veijo T; Belevich, Ilya; Li, Shiqian; Karhinen, Leena; Vihinen, Helena; Vigouroux, Corinne; Magré, Jocelyne; Thiele, Christoph; Hölttä-Vuori, Maarit; Jokitalo, Eija; Ikonen, Elina


    Seipin is an endoplasmic reticulum (ER) membrane protein implicated in lipid droplet (LD) biogenesis and mutated in severe congenital lipodystrophy (BSCL2). Here, we show that seipin is stably associated with nascent ER-LD contacts in human cells, typically via one mobile focal point per LD Seipin appears critical for such contacts since ER-LD contacts were completely missing or morphologically aberrant in seipin knockout and BSCL2 patient cells. In parallel, LD mobility was increased and protein delivery from the ER to LDs to promote LD growth was decreased. Moreover, while growing LDs normally acquire lipid and protein constituents from the ER, this process was compromised in seipin-deficient cells. In the absence of seipin, the initial synthesis of neutral lipids from exogenous fatty acid was normal, but fatty acid incorporation into neutral lipids in cells with pre-existing LDs was impaired. Together, our data suggest that seipin helps to connect newly formed LDs to the ER and that by stabilizing ER-LD contacts seipin facilitates the incorporation of protein and lipid cargo into growing LDs in human cells. © 2016 The Authors. Published under the terms of the CC BY NC ND 4.0 license.

  2. Nuclear powered Mars cargo transport mission utilizing advanced ion propulsion

    Energy Technology Data Exchange (ETDEWEB)

    Galecki, D.L.; Patterson, M.J.


    Nuclear-powered ion propulsion technology was combined with detailed trajectory analysis to determine propulsion system and trajectory options for an unmanned cargo mission to Mars in support of manned Mars missions. A total of 96 mission scenarios were identified by combining two power levels, two propellants, four values of specific impulse per propellant, three starting altitudes, and two starting velocities. Sixty of these scenarios were selected for a detailed trajectory analysis; a complete propulsion system study was then conducted for 20 of these trajectories. Trip times ranged from 344 days for a xenon propulsion system operating at 300 kW total power and starting from lunar orbit with escape velocity, to 770 days for an argon propulsion system operating at 300 kW total power and starting from nuclear start orbit with circular velocity. Trip times for the 3 MW cases studied ranged from 356 to 413 days. Payload masses ranged from 5700 to 12,300 kg for the 300 kW power level, and from 72,200 to 81,500 kg for the 3 MW power level.

  3. Opportunity of Constructing a Cargo Terminal – Case Study Brașov International Airport, Romania

    Directory of Open Access Journals (Sweden)

    Gabriel BRĂTUCU


    Full Text Available Air transport and especially air cargo transport became ever more important during the last 25 years, with a signifi cant impact upon economic development. Air cargo transport supports regional economic development, provided there is suffi cient local demand for its services. In our study, we have identifi ed signifi cant elements of the impact a cargo terminal at the International Brașov-Ghimbav Airport would have upon local economic development. For this purpose, we have conducted a quantitative market research. We have reached the conclusion that constructing a cargo terminal at the Brașov-Ghimbav Airport is a necessary investment in the current economic context, with an important contribution to the economic development of its surrounding counties. The positive results registered in our study could contribute to improving the economic and fi nancial prospects of Brașov-Ghimbav Airport and attract investors in this project.

  4. 78 FR 79071 - National Maritime Strategy Symposium: Cargo Opportunities and Sealift Capacity (United States)


    ... intended to develop a robust national maritime strategy. Stakeholders were asked to provide their ideas for... Maritime Administration National Maritime Strategy Symposium: Cargo Opportunities and Sealift Capacity... listen-only information January 10, 2014. distributed to registrants. National Maritime Strategy...

  5. DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family

    DEFF Research Database (Denmark)

    Franch, Oskar; Iacovelli, Federico; Falconi, Mattia


    In the present study we investigate the mechanism behind temperature controlled cargo uptake using a truncated octahedral DNA cage scaffold functionalized with one, two, three or four hairpin forming DNA strands inserted in one corner of the structure. This investigation was inspired by our...... previous demonstration of temperature controlled reversible encapsulation of the cargo enzyme, horseradish peroxidase, in the cage with four hairpin forming strands. However, in this previous study the mechanism of cargo uptake was not directly addressed (Juul, et al., Temperature-Controlled Encapsulation...... and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage, ACS Nano, 2013, 7, 9724–9734). In the present study we use a combination of molecular dynamics simulations and in vitro analyses to unravel the mechanism of cargo uptake in hairpin containing DNA cages. We find that two hairpin...

  6. Matrix-dependent local retention of secretory vesicle cargo in cortical neurons

    NARCIS (Netherlands)

    de Wit, J.; Toonen, R.F.G.; Verhage, M.


    Neurons secrete many diffusible signals from synaptic and other secretory vesicles. We characterized secretion of guidance cues, neuropeptides, neurotrophins, and proteases from single secretory vesicles using pHluorin-tagged cargo in cortical neurons. Stimulation triggered transient and persistent

  7. 46 CFR 38.15-5 - Cargo hose-TB/ALL. (United States)


    ... the cargo are carried on board the vessel, they shall be of flexible metal and fabricated of seamless steel pipe and flexible joints of steel or bronze, or of other suitable material resistant to the action...

  8. Diffusive transport of molecular cargo tethered to a DNA origami platform. (United States)

    Kopperger, Enzo; Pirzer, Tobias; Simmel, Friedrich C


    Fast and efficient transport of molecular cargoes along tracks or on supramolecular platforms is an important prerequisite for the development of future nanorobotic systems and assembly lines. Here, we study the diffusive transport of DNA cargo strands bound to a supramolecular DNA origami structure via an extended tether arm. For short distances (on the order of a few nanometers), transport from a start to a target site is found to be less efficient than for direct transfer without tether. For distances on the scale of the origami platform itself, however, cargo transfer mediated by a rigid tether arm occurs very fast and robust, whereas a more flexible, hinged tether is found to be considerably less efficient. Our results suggest diffusive motion on a molecular tether as a highly efficient mechanism for fast transfer of cargoes over long distances.

  9. 75 FR 22532 - Federal Motor Vehicle Safety Standards; Cargo Carrying Capacity (United States)


    ... rack (24 pounds), roof bike mount (13 pounds), kayak carrier (11 pounds) and remote starter (3 pounds..., roof rack, kayak carrier) are designed to optimize the vehicle's cargo carrying capabilities. With...

  10. Holographic bulk reconstruction with α' corrections (United States)

    Roy, Shubho R.; Sarkar, Debajyoti


    We outline a holographic recipe to reconstruct α' corrections to anti-de Sitter (AdS) (quantum) gravity from an underlying CFT in the strictly planar limit (N →∞ ). Assuming that the boundary CFT can be solved in principle to all orders of the 't Hooft coupling λ , for scalar primary operators, the λ-1 expansion of the conformal dimensions can be mapped to higher curvature corrections of the dual bulk scalar field action. Furthermore, for the metric perturbations in the bulk, the AdS /CFT operator-field isomorphism forces these corrections to be of the Lovelock type. We demonstrate this by reconstructing the coefficient of the leading Lovelock correction, also known as the Gauss-Bonnet term in a bulk AdS gravity action using the expression of stress-tensor two-point function up to subleading order in λ-1.

  11. Bulk amorphous Mg-based alloys

    DEFF Research Database (Denmark)

    Pryds, Nini


    and a low glass transition temperature. The alloys were prepared by using a relatively simple technique, i.e. rapid cooling of the melt in a copper wedge mould. The essential structural changes that are achieved by going from the amorphous to the crystalline state through the supercooled liquid state...... are discussed in this paper. On the basis of these measurements phase diagrams of the different systems were constructed. Finally, it is demonstrated that when pressing the bulk amorphous alloy onto a metallic dies at temperatures within the supercooled liquid region, the alloy faithfully replicates the surface......The present paper describes the preparation and properties of bulk amorphous quarternary Mg-based alloys and the influence of additional elements on the ability of the alloy to form bulk amorphous. The main goal is to find a Mg-based alloy system which shows both high strength to weight ratio...

  12. Orchestrating Bulk Data Movement in Grid Environments

    Energy Technology Data Exchange (ETDEWEB)

    Vazhkudai, SS


    Data Grids provide a convenient environment for researchers to manage and access massively distributed bulk data by addressing several system and transfer challenges inherent to these environments. This work addresses issues involved in the efficient selection and access of replicated data in Grid environments in the context of the Globus Toolkit{trademark}, building middleware that (1) selects datasets in highly replicated environments, enabling efficient scheduling of data transfer requests; (2) predicts transfer times of bulk wide-area data transfers using extensive statistical analysis; and (3) co-allocates bulk data transfer requests, enabling parallel downloads from mirrored sites. These efforts have demonstrated a decentralized data scheduling architecture, a set of forecasting tools that predict bandwidth availability within 15% error and co-allocation architecture, and heuristics that expedites data downloads by up to 2 times.

  13. Massively parallel delivery of large cargo into mammalian cells with light pulses


    Wu, YC; Wu, TH.; Clemens, DL; Lee, BY; Wen, X.; Horwitz, MA; Teitell, MA; Chiou, PY


    © 2015 Nature America, Inc. We report a high-throughput platform for delivering large cargo elements into 100,000 cells in 1 min. Our biophotonic laser-assisted surgery tool (BLAST) generates an array of microcavitation bubbles that explode in response to laser pulsing, forming pores in adjacent cell membranes through which cargo is gently driven by pressurized flow. The platform delivers large items including bacteria, enzymes, antibodies and nanoparticles into diverse cell types with high e...

  14. Research on combination forecast of port cargo throughput based on time series and causality analysis

    Directory of Open Access Journals (Sweden)

    Chi Zhang


    Full Text Available Purpose: The purpose of this paper is to develop a combined model composed of grey-forecast model and Logistic-growth-curve model to improve the accuracy of forecast model of cargo throughput for the port. The authors also use the existing data of a current port to verify the validity of the combined model.Design/methodology/approach: A literature review is undertaken to find the appropriate forecast model of cargo throughput for the port. Through researching the related forecast model, the authors put together the individual models which are significant to study further. Finally, the authors combine two individual models (grey-forecast model and Logistic-growth-curve model into one combined model to forecast the port cargo throughput, and use the model to a physical port in China to testify the validity of the model.Findings: Test by the perceptional data of cargo throughput in the physical port, the results show that the combined model can obtain relatively higher forecast accuracy when it is not easy to find more information. Furthermore, the forecast made by the combined model are more accurate than any of the individual ones.Research limitations/implications: The study provided a new combined forecast model of cargo throughput with a relatively less information to improve the accuracy rate of the forecast. The limitation of the model is that it requires the cargo throughput of the port have an S-shaped change trend.Practical implications: This model is not limited by external conditions such as geographical, cultural. This model predicted the port cargo throughput of one real port in China in 2015, which provided some instructive guidance for the port development.Originality/value: This is the one of the study to improve the accuracy rate of the cargo throughput forecast with little information.


    Directory of Open Access Journals (Sweden)

    M.M. Moustafa


    Full Text Available The global logistics center for the storage and handling of grain which will be constructed at Damietta port will extremely increase the annual movement of grain through Cairo-Damietta waterway. Therefore, the demand for inland grain bulk ships has increased significantly in the recent years. This paper introduces a procedure to find out the fleet size and optimum characteristics of self-propelled grain bulk ships working between Cairo and Damietta through River Nile. The characteristics of the Cairo–Damietta waterway are investigated to define the constraints on dimensions and speed for such ship type. Also, mathematical model for the objective function was developed considering: powering, voyage, weight, stability and cost calculation. In this research, Specific cost (Sc, cost of transporting one ton of cargo a distance of one kilometre, is considered as the objective function for this optimization process. This optimization problem is handled as a single objective nonlinear constrained optimization problem using a specially developed computer program. Solutions are generated by varying design variables systematically in certain steps. The best of these solutions is then taken as the estimated optimum. Finally, the problem is presented, the main constrains analyzed and the optimum solution shown.

  16. Thermal relics in cosmology with bulk viscosity

    Energy Technology Data Exchange (ETDEWEB)

    Iorio, A. [Charles University in Prague, Faculty of Mathematics and Physics, Prague (Czech Republic); Lambiase, G. [Universita di Salerno, Dipartimento di Fisica E.R. Caianiello, Fisciano (Italy); INFN, Gruppo Collegato di Salerno, Fisciano (Italy)


    In this paper we discuss some consequences of cosmological models in which the primordial cosmic matter is described by a relativistic imperfect fluid. The latter takes into account the dissipative effects (bulk viscosity) arising from different cooling rates of the fluid components in the expanding Universe. We discuss, in particular, the effects of the bulk viscosity on Big Bang Nucleosynthesis and on the thermal relic abundance of particles, looking at recent results of PAMELA experiment. The latter has determined an anomalous excess of positron events, which cannot be explained by conventional cosmology and particle physics. (orig.)

  17. A mechanistic analysis of bulk powder caking (United States)

    Calvert, G.; Curcic, N.; Ghadiri, M.


    Bulk powder transformations, such as caking, can lead to numerous problems within industry when storing or processing materials. In this paper a new Environmental Caking Rig (ECR) is introduced and has been used to evaluate the caking propensity of a hygroscopic powder as a function of temperature, Relative Humidity (RH), mechanical stress and also when RH is cycled. A linear relationship exists between cake strength and the extent of bulk deformation, here defined by the engineering strain. An empirical model has been used to predict the caking behaviour based on consolidation stress and environmental conditions.

  18. Synthesis of Bulk Superconducting Magnesium Diboride

    Directory of Open Access Journals (Sweden)

    Margie Olbinado


    Full Text Available Bulk polycrystalline superconducting magnesium diboride, MgB2, samples were successfully prepared via a one-step sintering program at 750°C, in pre Argon with a pressure of 1atm. Both electrical resistivity and magnetic susceptibility measurements confirmed the superconductivity of the material at 39K, with a transition width of 5K. The polycrystalline nature, granular morphology, and composition of the sintered bulk material were confirmed using X-ray diffractometry (XRD, scanning electron microscopy (SEM, and energy dispersive X-ray analysis (EDX.

  19. Quantifying the Dynamic Interactions Between a Clathrin-Coated Pit and Cargo Molecules (United States)

    Weigel, Aubrey; Tamkun, Michael; Krapf, Diego


    Clathrin-mediated endocytosis is a major pathway of internalization of cargo in eukaryotic cells. This process involves the recruitment of cargo molecules into a growing clathrin-coated pit (CCP). However, cargo-CCP interactions are difficult to study because CCPs display a large degree of lifetime heterogeneity and the interactions with cargo molecules evolve over time. We use single-molecule total internal reflection fluorescence (TIRF) microscopy, in combination with automatic detection and tracking algorithms, to directly visualize the recruitment of individual voltage-gated potassium channels into forming CCPs in living cells. Contrary to widespread ideas, cargo often escapes from a pit before abortive CCP termination or endocytic vesicle production. By measuring tens of thousands of capturing events, we build the distribution of capture times and the times that cargo remains confined to a CCP. An analytical stochastic model is developed and compared to the measured distributions. Due to the dynamic nature of the pit, the model is non-Markovian and it displays long-tail power law statistics. Our findings identify one source of the large heterogeneities observed in CCP maturation and provide a mechanism for the anomalous diffusion of proteins in the plasma membrane. This work was supported by National Science Foundation Grant PHY-0956714.

  20. Stall force of a cargo driven by N interacting motor proteins (United States)

    Bhat, Deepak; Gopalakrishnan, Manoj


    We study a generic one-dimensional model for an intracellular cargo driven by N motor proteins against an external applied force. The model includes motor-cargo and motor-motor interactions. The cargo motion is described by an over-damped Langevin equation, while motor dynamics is specified by hopping rates which follow a local detailed balance condition with respect to the change in energy per hopping event. Based on this model, we show that the stall force, the mean external force corresponding to zero mean cargo velocity, is completely independent of the details of the interactions and is, therefore, always equal to the sum of the stall forces of the individual motors. This exact result is arrived on the basis of a simple assumption: the (macroscopic) state of stall of the cargo is analogous to a state of thermodynamic equilibrium, and is characterized by vanishing net probability current between any two microstates, with the latter specified by motor positions relative to the cargo. The corresponding probability distribution of the microstates under stall is also determined. These predictions are in complete agreement with numerical simulations, carried out using specific forms of interaction potentials.

  1. Nonlinear roll damping of a barge with and without liquid cargo in spherical tanks

    Directory of Open Access Journals (Sweden)

    Wenhua Zhao


    Full Text Available Damping plays a significant role on the maximum amplitude of a vessel's roll motion, in particular near the resonant frequency. It is a common practice to predict roll damping using a linear radiation–diffraction code and add that to a linearized viscous damping component, which can be obtained through empirical, semi-empirical equations or free decay tests in calm water. However, it is evident that the viscous roll damping is nonlinear with roll velocity and amplitude. Nonlinear liquid cargo motions inside cargo tanks also contribute to roll damping, which when ignored impedes the accurate prediction of maximum roll motions. In this study, a series of free decay model tests is conducted on a barge-like vessel with two spherical tanks, which allows a better understanding of the nonlinear roll damping components considering the effects of the liquid cargo motion. To examine the effects of the cargo motion on the damping levels, a nonlinear model is adopted to calculate the damping coefficients. The liquid cargo motion is observed to affect both the linear and the quadratic components of the roll damping. The flow memory effect on the roll damping is also studied. The nonlinear damping coefficients of the vessel with liquid cargo motions in spherical tanks are obtained, which are expected to contribute in configurations involving spherical tanks.

  2. A fluid membrane enhances the velocity of cargo transport by small teams of kinesin-1 (United States)

    Li, Qiaochu; Tseng, Kuo-Fu; King, Stephen J.; Qiu, Weihong; Xu, Jing


    Kinesin-1 (hereafter referred to as kinesin) is a major microtubule-based motor protein for plus-end-directed intracellular transport in live cells. While the single-molecule functions of kinesin are well characterized, the physiologically relevant transport of membranous cargos by small teams of kinesins remains poorly understood. A key experimental challenge remains in the quantitative control of the number of motors driving transport. Here we utilized "motile fraction" to overcome this challenge and experimentally accessed transport by a single kinesin through the physiologically relevant transport by a small team of kinesins. We used a fluid lipid bilayer to model the cellular membrane in vitro and employed optical trapping to quantify the transport of membrane-enclosed cargos versus traditional membrane-free cargos under identical conditions. We found that coupling motors via a fluid membrane significantly enhances the velocity of cargo transport by small teams of kinesins. Importantly, enclosing a cargo in a fluid lipid membrane did not impact single-kinesin transport, indicating that membrane-dependent velocity enhancement for team-based transport arises from altered interactions between kinesins. Our study demonstrates that membrane-based coupling between motors is a key determinant of kinesin-based transport. Enhanced velocity may be critical for fast delivery of cargos in live cells.

  3. Polymeric colloidal particulate systems: intelligent tools for intracellular targeting of antileishmanial cargos. (United States)

    Asthana, Shalini; Gupta, Pramod K; Chaurasia, Mohini; Dube, Anuradha; Chourasia, Manish K


    Targeted cargo delivery systems can overcome drawbacks associated with antileishmanials delivery, by defeating challenges of physiological barriers. Various colloidal particulate systems have been developed in the past; few of them even achieved success in the market, but still are limited in some ways. This review is focused on the pathobiology of leishmaniasis, interactions of particulate systems with biological environment, targeting strategies along with current conventional and vaccine therapies with special emphasis on polymeric nanotechnology for effective antileishmanial cargo delivery. The problems concerned with limited accessibility of chemotherapeutic cargos in conventional modes to Leishmania-harboring macrophages, their toxicity, and resistant parasitic strain development can be sorted out through target-specific delivery of cargos. Vaccination is another therapeutic approach employing antigen alone or adjuvant combinations delivered by means of a carrier, and can provide preventive measures against human leishmaniasis (HL). Therefore, there is an urgent need of designing site-specific antileishmanial cargo carriers for safe and effective management of HL. Among various colloidal carriers, polymeric particulate systems hold tremendous potential as an effective delivery tool by providing control over spatial and temporal distribution of cargos after systemic or localized administration along with enhancing their stability profile at a comparatively cost-effective price leading to improved chances of commercial applicability.

  4. Air cargo market outlook and impact via the NASA CLASS project. [Cargo/Logistics Airlift Systems Study (United States)

    Winston, M. M.; Conner, D. W.


    An overview is given of the Cargo/Logistics Airlift Systems Study (CLASS) project which was a 10 man-year effort carried out by two contractor teams, aimed at defining factors impacting future system growth and obtaining market requirements and design guidelines for future air freighters. Growth projection was estimated by two approaches: one, an optimal systems approach with a more efficient and cost effective system considered as being available in 1990; and the other, an evolutionary approach with an econometric behavior model used to predict long term evolution from the present system. Both approaches predict significant growth in demand for international air freighter services and less growth for U.S. domestic services. Economic analysis of air freighter fleet options indicate very strong market appeal of derivative widebody transports in 1990 with little incentive to develop all new dedicated air freighters utilizing the 1990's technology until sometime beyond the year 2000. Advanced air freighters would be economically attractive for a wide range of payload sizes (to 500 metric tons), however, if a government would share in the RD and T costs by virtue of its needs for a slightly modified version of a civil air freighter design (a.g. military airlifter).

  5. Length of encapsidated cargo impacts stability and structure of in vitro assembled alphavirus core-like particles (United States)

    Rayaprolu, Vamseedhar; Moore, Alan; Che-Yen Wang, Joseph; Goh, Boon Chong; Perilla, Juan R.; Zlotnick, Adam; Mukhopadhyay, Suchetana


    In vitro assembly of alphavirus nucleocapsid cores, called core-like particles (CLPs), requires a polyanionic cargo. There are no sequence or structure requirements to encapsidate single-stranded nucleic acid cargo. In this work, we wanted to determine how the length of the cargo impacts the stability and structure of the assembled CLPs. We hypothesized that cargo neutralizes the basic region of the alphavirus capsid protein and if the cargo is long enough, it will also act to scaffold the CP monomers together. Experimentally we found that CLPs encapsidating short 27mer oligonucleotides were less stable than CLPs encapsidating 48mer or 90mer oligonucleotides under different chemical and thermal conditions. Furthermore, cryo-EM studies showed there were structural differences between CLPs assembled with 27mer and 48mer cargo. To mimic the role of the cargo in CLP assembly we made a mutant (4D) where we substituted a cluster of four Lys residues in the CP with four Asp residues. We found that these few amino acid substitutions were enough to initiate CLP assembly in the absence of cargo. The cargo-free 4D CLPs show higher resistance to ionic strength and increased temperature compared to wild-type cargo containing CLPs suggesting their CLP assembly mechanism might also be different.

  6. X-Ray Cargo Inspection: Status and Trends (United States)

    Chen, Gongyin; Bjorkholm, Paul; Fox, Timothy R.; Wilson, Zane; Bonsergent, Xavier


    Over the past several years, x-ray cargo inspection has experienced tremendous growth. There are several hundred systems in use world wide and a few new units are installed every week. Fielded systems are mostly located in north and West Africa, Middle East, Europe (especially Russia), East Asia, and South America. The majority of systems are powered by Varian M3, M6 or M9 Linac x-ray sources. The spatial resolution of these systems is typically 3-5 mm, penetration ranges from around 200 mm to 450 mm of steel and contrast sensitivity is typically 1-4%. Inspection throughput ranges from about 20 trucks per hour to 200 trucks per hour. Currently the systems are primarily used to fight import tax evasion and smuggling of controlled substances. There are a few clear trends: Imaging performance has been steadily improving; a variety of systems have been developed to fit different needs; also, there is a strong effort in material discrimination, or even identification and automatic detection. The last, but not least trend is a shift to security applications. The US government has launched major efforts such as CAARS and JINII to fight nuclear threat and systems that can automatically detect a small amount of high atomic number materials are being developed. This paper only covers RF linear accelerator based X-ray sources, which prevail in the industry. Induction accelerators (Betatrons) have some limited use in low-end imaging systems and high duty factors sources have recently been proposed for study.

  7. Cellulosic ethanol byproducts as a bulking agent (United States)

    J.M. Considine; D. Coffin; J.Y. Zhu; D.H. Mann; X. Tang


    Financial enhancement of biomass value prior to pulping requires subsequent use of remaining materials; e.g., high value use of remaining stock material after cellulosic ethanol production would improve the economics for cellulosic ethanol. In this work, use of enzymatic hydrolysis residual solids (EHRS), a cellulosic ethanol byproduct, were investigated as a bulking...


    Directory of Open Access Journals (Sweden)



    Full Text Available This paper presents the experiments that were conducted on the installation of continuous bulking and thermofixing “SUPERBA” type TVP-2S for optimization of the plush yarns bulking process. There were considered plush yarns Nm 6.5/2, made of the fibrous blend of 50% indigenous wool sort 41 and 50% PES. In the first stage, it performs a thermal treatment with a turboprevaporizer at a temperature lower than thermofixing temperature, at atmospheric pressure, such that the plush yarns - deposed in a freely state on a belt conveyor - are uniformly bulking and contracting. It was followed the mathematical modeling procedure, working with a factorial program, rotatable central composite type, and two independent variables. After analyzing the parameters that have a direct influence on the bulking degree, there were selected the pre-vaporization temperature (coded x1,oC and the velocity of belt inside pre-vaporizer (coded x 2, m/min. As for the dependent variable, it was chosen the plush yarn diameter (coded y, mm. There were found the coordinates of the optimal point, and then this pair of values was verified in practice. These coordinates are: x1optim= 90oC and x 2optim= 6.5 m/min. The conclusion is that the goal was accomplished: it was obtained a good cover degree f or double-plush carpets by reducing the number of tufts per unit surface.

  9. Characteristics of bulk liquid undercooling and crystallization ...

    Indian Academy of Sciences (India)

    157–161. c Indian Academy of Sciences. Characteristics of bulk liquid undercooling and crystallization behaviors of jet electrodeposition Ni–W–P alloy. J K YU. ∗. , Y H WANG, G Z XING, Q QIAO, B LIU, Z J CHU, C L LI and F YOU. State Key Laboratory of Metastable Materials Science and Technology, Yanshan University,.

  10. Characteristics of bulk liquid undercooling and crystallization ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 1. Characteristics of bulk liquid undercooling and crystallization behaviors of jet electrodeposition Ni–W–P alloy. J K Yu Y H Wang G Z Xing Q Qiao B Liu Z J Chu C L Li F You. Volume 38 Issue 1 February 2015 pp 157-161 ...

  11. Failure by fracture in bulk metal forming

    DEFF Research Database (Denmark)

    Silva, C.M.A.; Alves, Luis M.; Nielsen, Chris Valentin


    This paper revisits formability in bulk metal forming in the light of fundamental concepts of plasticity,ductile damage and crack opening modes. It proposes a new test to appraise the accuracy, reliability and validity of fracture loci associated with crack opening by tension and out-of-plane shear...

  12. Thermal bulk polymerization of cholesteryl acrylate

    NARCIS (Netherlands)

    de Visser, A.C.; de Groot, K.; Feijen, Jan; Bantjes, A.


    The thermal bulk polymerization of cholesteryl acrylate was carried out in the solid phase, the mesomorphic phase, and the liquid phase to study the effect of monomer ordering on polymerization rate and polymer properties. The rate increased with decreasing ordering (or enhanced mobility) of the

  13. A large-scale biomass bulk terminal

    NARCIS (Netherlands)

    Wu, M.R.


    This research explores the possibility of a large-scale bulk terminal in West Europe dedicated to handle solid and liquid biomass materials. Various issues regarding the conceptual design of such a terminal have been investigated and demonstrated in this research: the potential biomass materials

  14. Bulk metamaterials: Design, fabrication and characterization

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Alabastri, Alessandro


    Bulk metamaterials claim a lot of attention worldwide. We report about our activity and advances in design, fabrication and characterization of metal-dielectric composites with three-dimensional lattices. The nomenclature of designs exhibiting negative index behaviour in the near infrared includes...

  15. Polonium bulk and surface vibrational dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Tigrine, Rachid; Bourahla, Boualem [Laboratoire de Physique PEC UMR 6087, Universite du Maine, Le Mans (France); Laboratoire de Physique et Chimie Quantique, Universite de Tizi Ouzou (Algeria); Khater, Antoine


    Calculations are presented for the bulk phonons and for surface Rayleigh phonons and resonances for Polonium, the only element known to form in the simple cubic lattice. The static stability of this lattice has been confirmed recently by ab initio simulations which yield two bulk elastic constants, c{sub 11} and c{sub 12}. Constitutive equations are derived for the isotropic cubic lattice based upon the Fuchs's method. This permits effectively a numerical evaluation of central potential force constants for Polonium from the ab initio results. Numerical calculations are then made for the material vibration dynamics in the force constant model with the use of the matching method. The numerical applications yield for Polonium the bulk phonon branches along[100],[110], and [111], and the Rayleigh phonons and surface resonances along the[010] direction in an unreconstructed (001) surface. The local vibration densities of states are calculated for bulk and surface sites for this element. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  16. Modelling ventilated bulk storage of agromaterials

    NARCIS (Netherlands)

    Grubben, N.L.M.; Keesman, K.J.


    Storage of season-dependent agro-materials is a key process in providing food, feed and biomass throughout the whole year. We review the state of the art in physical modelling, simulation and control of ventilated bulk storage facilities, and in particular the storage of potatoes, from a

  17. Teaching Advanced SQL Skills: Text Bulk Loading (United States)

    Olsen, David; Hauser, Karina


    Studies show that advanced database skills are important for students to be prepared for today's highly competitive job market. A common task for database administrators is to insert a large amount of data into a database. This paper illustrates how an up-to-date, advanced database topic, namely bulk insert, can be incorporated into a database…

  18. Transformation kinetics for surface and bulk nucleation

    Energy Technology Data Exchange (ETDEWEB)

    Villa, Elena, E-mail: [University of Milan, Department of Mathematics, via Saldini 50, 20133 Milano (Italy); Rios, Paulo R., E-mail: [Universidade Federal Fluminense, Escola de Engenharia Industrial Metalurgica de Volta Redonda, Av. dos Trabalhadores 420, 27255-125 Volta Redonda, RJ (Brazil)] [RWTH Aachen University, Institut fuer Metallkunde und Metallphysik, D-52056 Aachen (Germany)


    A rigorous mathematical approach based on the causal cone and stochastic geometry concepts is used to derive new exact expressions for transformation kinetics theory. General expressions for the mean volume density and the volume fraction are derived for both surface and bulk nucleation in a general Borel subset of R{sup 3}. In practice, probably any specimen shape of engineering interest is going to be a Borel set. An expression is also derived for the important case of polyhedral shape, in which surface nucleation may take place on the faces, edges and vertices of the polyhedron as well as within the bulk. Moreover, explicit expressions are given for surface and bulk nucleation for three specific shapes of engineering relevance: two parallel planes, an infinitely long cylinder and a sphere. Superposition is explained in detail and it permits the treatment of situations in which surface and bulk nucleation take place simultaneously. The new exact expressions presented here result in a significant increase in the number of exactly solvable cases available to formal kinetics.

  19. Scientific computing on bulk synchronous parallel architectures

    NARCIS (Netherlands)

    Bisseling, R.H.; McColl, W.F.


    Bulk synchronous parallel architectures oer the prospect of achieving both scalable parallel performance and architecture independent parallel software. They provide a robust model on which to base the future development of general purpose parallel computing systems. In this paper, we theoretically

  20. Radiopacity of bulk fill flowable resin composite materials | Yildirim ...

    African Journals Online (AJOL)

    Objectives: The purpose of this study was to evaluate the radiopacity of currently marketed bulk fill flowable dental composite materials (Beautifil Bulk Flowable, SDR Flow, Filtek Bulk Fill Flow, and x‑tra Base Bulk Fill). Materials and Methods: Six specimens of each material with a thickness of 1 mm were prepared, and ...

  1. Survey of transportation of liquid bulk chemicals in the Baltic Sea

    Energy Technology Data Exchange (ETDEWEB)

    Posti, A.; Hakkinen, J.


    This study is made as a part of the Chembaltic (Risks of Maritime Transportation of Chemicals in Baltic Sea) project which gathers information on the chemicals transported in the Baltic Sea. The purpose of this study is to provide an overview of handling volumes of liquid bulk chemicals (including liquefied gases) in the Baltic Sea ports and to find out what the most transported liquid bulk chemicals in the Baltic Sea are. Oil and oil products are also viewed in this study but only in a general level. Oils and oil products may also include chemical-related substances (e.g. certain bio-fuels which belong to MARPOL annex II category) in some cargo statistics. Chemicals in packaged form are excluded from the study. Most of the facts about the transport volumes of chemicals presented in this study are based on secondary written sources of Scandinavian, Russian, Baltic and international origin. Furthermore, statistical sources, academic journals, periodicals, newspapers and in later years also different homepages on the Internet have been used as sources of information. Chemical handling volumes in Finnish ports were examined in more detail by using a nationwide vessel traffic system called PortNet. Many previous studies have shown that the Baltic Sea ports are annually handling more than 11 million tonnes of liquid chemicals transported in bulk. Based on this study, it appears that the number may be even higher. The liquid bulk chemicals account for approximately 4 % of the total amount of liquid bulk cargoes handled in the Baltic Sea ports. Most of the liquid bulk chemicals are handled in Finnish and Swedish ports and their proportion of all liquid chemicals handled in the Baltic Sea is altogether over 50 %. The most handled chemicals in the Baltic Sea ports are methanol, sodium hydroxide solution, ammonia, sulphuric and phosphoric acid, pentanes, aromatic free solvents, xylenes, methyl tert-butyl ether (MTBE) and ethanol and ethanol solutions. All of these chemicals

  2. Bulk sulfur (S) deposition in China (United States)

    Liu, Lei; Zhang, Xiuying; Wang, Shanqian; Zhang, Wuting; Lu, Xuehe


    A systematic dataset of an observation network on a national scale has been organized to investigate the spatial distribution of bulk sulfur (S) deposition (Sdep) throughout China during 2000-2013, representing by far the most detailed data set to track the bulk sulfur deposition throughout China since 2000. Such a dataset is needed for ecosystem studies and for developing emission control policies. Bulk Sdep values showed great variations, ranging from 2.17 to 70.55 kg ha-1 y-1, with an average of 22.99 kg ha-1 y-1. The average rate of bulk Sdep located in East Coastal region (35.97 kg ha-1 y-1), Middle Yangtze region (57.90 kg ha-1 y-1), Middle Yellow River region (23.42 kg ha-1 y-1), North Coastal region (42.19 kg ha-1 y-1), Northeast region (34.28 kg ha-1 y-1), South Coastal region (36.97 kg S ha-1 y-1), Southwest region (33.85 kg ha-1 y-1) was 4.50, 7.24, 2.93, 5.28, 4.29, 4.63 and 4.24 times than that in Northwest region (7.99 kg ha-1 y-1). Bulk Sdep over China was mainly from fossil fuel combustion (76.96%), biomass burning (7.64%), crust (6.22%), aged sea salt (5.48%) and agriculture (3.68%). A systematic observation network on a national scale should be established to conduct a long-term monitoring atmospheric Sdep (including wet and dry deposition), based on exiting ecological stations administrated by different departments in China.

  3. Mechanical design engineering. NASA/university advanced design program: Lunar Bulk Material Transport Vehicle (United States)

    Daugherty, Paul; Griner, Stewart; Hendrix, Alan; Makarov, Chris; Martiny, Stephen; Meyhoefer, Douglas Ralph; Platt, Cody Claxton; Sivak, John; Wheeler, Elizabeth Fitch


    The design of a Lunar Bulk Material Transport Vehicle (LBMTV) is discussed. Goals set in the project include a payload of 50 cubic feet of lunar soil with a lunar of approximately 800 moon-pounds, a speed of 15 mph, and the ability to handle a grade of 20 percent. Thermal control, an articulated steering mechanism, a dump mechanism, a self-righting mechanism, viable power sources, and a probable control panel are analyzed. The thermal control system involves the use of small strip heaters to heat the housing of electronic equipment in the absence of sufficient solar radiation and multi-layer insulation during periods of intense solar radiation. The entire system uses only 10 W and weighs about 60 pounds, or 10 moon-pounds. The steering mechanism is an articulated steering joint at the center of the vehicle. It utilizes two actuators and yields a turning radius of 10.3 feet. The dump mechanism rotates the bulk material container through an angle of 100 degree using one actuator. The self-righting mechanism consists of two four bar linkages, each of which is powered by the same size actuator as the other linkages. The LBMTV is powered by rechargeable batteries. A running time of at least two hours is attained under a worst case analysis. The weight of the batteries is 100 pounds. A control panel consisting of feedback and control instruments is described. The panel includes all critical information necessary to control the vehicle remotely. The LBMTV is capable of handling many types of cargo. It is able to interface with many types of removable bulk material containers. These containers are made to interface with the three-legged walker, SKITTER. The overall vehicle is about 15 feet in length and has a weight of about 1000 pounds, or 170 lunar pounds.

  4. FAM21 directs SNX27-retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus. (United States)

    Lee, Seongju; Chang, Jaerak; Blackstone, Craig


    The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins. The SNX27-retromer complex has recently been identified as a major endosomal hub that regulates endosome-to-plasma membrane recycling by preventing lysosomal entry of cargoes. Here, we show that SNX27 directly interacts with FAM21, which also binds retromer, within the Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) complex. This interaction is required for the precise localization of SNX27 at an endosomal subdomain as well as for recycling of SNX27-retromer cargoes. Furthermore, FAM21 prevents cargo transport to the Golgi apparatus by controlling levels of phosphatidylinositol 4-phosphate, which facilitates cargo dissociation at the Golgi. Together, our results demonstrate that the SNX27-retromer-WASH complex directs cargoes to the plasma membrane by blocking their transport to lysosomes and the Golgi.

  5. Perbandingan tingkat kebocoran mikro resin komposit bulk-filldengan teknik penumpatan oblique incremental dan bulk

    Directory of Open Access Journals (Sweden)

    Dimas Puja Permana


    Full Text Available Micoleakage comparison of bulk-fillcomposite beetwen oblique incremental and bulk placement techniques. Resin composite bulk-fill was a new type of resin composite that speed up application process of composite. The concept of bulk-fill composite allows composite to fill at a depth of 4 mm and minimizes polymerization shrinkage. This study aims to determine the comparison of placement techniques (oblique incremental/bulk of bulk-fill composite on microleakage in class I preparations. Thirty two human maxillary premolar were stored in distilled water, then Class I preparations were made with the depth of the cavity which was 4 mm (3 x 3 x 4. The teeth were randomly divided into two groups, group 1 uses oblique incremental placement technique and group 2 with bulk placement technique. Samples were stored in an incubator at a temperature of 37 °C for 24 hours, then it was thermocycled manually, 100 cycles at temperature between 5 °C and 55 °C. Microleakage was measured using a digital microscope with a 100 X magnification in millimeters using a microscope micrometer calibration ruler with 0,1 mm level of accuracy after immersion in 0,3% methylene blue and sectioned using separating disc. The result of this study revealed that in group 1 microleakage range was 1.0 mm - 2.7 mm with an average 1.625 mm, and in group 2 microleakage range was 3.6 mm - 4.0 mm with an average of 3.763 mm. The data were analyzed using T-test. The analysis showed a significant difference between two groups (p <0.05. The conclusion of this study was bulk-fill composite in class I cavities with oblique incremental placement technique produces less microleakage than bulk placement technique.   ABSTRAK Resin komposit bulk-fill adalah resin komposit yang dirancang untuk mempercepat proses aplikasi resin komposit. Konsep bulk-fill memungkinkan resin komposit ditumpat sekaligus 4 mm dan mengalami pengerutan polimerisasi minimal. Penelitian ini bertujuan mengetahui efek teknik

  6. A proposed benchmark problem for cargo nuclear threat monitoring (United States)

    Wesley Holmes, Thomas; Calderon, Adan; Peeples, Cody R.; Gardner, Robin P.


    There is currently a great deal of technical and political effort focused on reducing the risk of potential attacks on the United States involving radiological dispersal devices or nuclear weapons. This paper proposes a benchmark problem for gamma-ray and X-ray cargo monitoring with results calculated using MCNP5, v1.51. The primary goal is to provide a benchmark problem that will allow researchers in this area to evaluate Monte Carlo models for both speed and accuracy in both forward and inverse calculational codes and approaches for nuclear security applications. A previous benchmark problem was developed by one of the authors (RPG) for two similar oil well logging problems (Gardner and Verghese, 1991, [1]). One of those benchmarks has recently been used by at least two researchers in the nuclear threat area to evaluate the speed and accuracy of Monte Carlo codes combined with variance reduction techniques. This apparent need has prompted us to design this benchmark problem specifically for the nuclear threat researcher. This benchmark consists of conceptual design and preliminary calculational results using gamma-ray interactions on a system containing three thicknesses of three different shielding materials. A point source is placed inside the three materials lead, aluminum, and plywood. The first two materials are in right circular cylindrical form while the third is a cube. The entire system rests on a sufficiently thick lead base so as to reduce undesired scattering events. The configuration was arranged in such a manner that as gamma-ray moves from the source outward it first passes through the lead circular cylinder, then the aluminum circular cylinder, and finally the wooden cube before reaching the detector. A 2 in.×4 in.×16 in. box style NaI (Tl) detector was placed 1 m from the point source located in the center with the 4 in.×16 in. side facing the system. The two sources used in the benchmark are 137Cs and 235U.

  7. Structural determinants in the bulk heterojunction. (United States)

    Acocella, Angela; Höfinger, Siegfried; Haunschmid, Ernst; Pop, Sergiu C; Narumi, Tetsu; Yasuoka, Kenji; Yasui, Masato; Zerbetto, Francesco


    Photovoltaics is one of the key areas in renewable energy research with remarkable progress made every year. Here we consider the case of a photoactive material and study its structural composition and the resulting consequences for the fundamental processes driving solar energy conversion. A multiscale approach is used to characterize essential molecular properties of the light-absorbing layer. A selection of bulk-representative pairs of donor/acceptor molecules is extracted from the molecular dynamics simulation of the bulk heterojunction and analyzed at increasing levels of detail. Significantly increased ground state energies together with an array of additional structural characteristics are identified that all point towards an auxiliary role of the material's structural organization in mediating charge-transfer and -separation. Mechanistic studies of the type presented here can provide important insights into fundamental principles governing solar energy conversion in next-generation photovoltaic devices.

  8. Bulk and shear viscosity in Hagedorn fluid

    Energy Technology Data Exchange (ETDEWEB)

    Tawfik, A.; Wahba, M. [Egyptian Center for Theoretical Physics (ECTP), MTI University, Faculty of Engineering, Cairo (Egypt)


    Assuming that the Hagedorn fluid composed of known particles and resonances with masses m <2 GeV obeys the first-order theory (Eckart) of relativistic fluid, we discuss the transport properties of QCD confined phase. Based on the relativistic kinetic theory formulated under the relaxation time approximation, expressions for bulk and shear viscosity in thermal medium of hadron resonances are derived. The relaxation time in the Hagedorn dynamical fluid exclusively takes into account the decay and eventually van der Waals processes. We comment on the in-medium thermal effects on bulk and shear viscosity and averaged relaxation time with and without the excluded-volume approach. As an application of these results, we suggest the dynamics of heavy-ion collisions, non-equilibrium thermodynamics and the cosmological models, which require thermo- and hydro-dynamics equations of state. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  9. Enhanced bulk polysilicon production using silicon tubes (United States)

    Jafri, Ijaz; Chandra, Mohan; Zhang, Hui; Prasad, Vish; Reddy, Chandra; Amato-Wierda, Carmela; Landry, Marc; Ciszek, Ted


    A novel technique using silicon tubes for the production of bulk polysilicon via chemical vapor deposition is presented. Our experimental studies with a model reactor indicate that the polysilicon growth inside the silicon tube (15.3 g) exceeds that of the calculated polysilicon growth on silicon slim rods (4.3 g) over 55 h of deposition time. A computational model is also being developed to simulate the growth rates of the model reactor. Preliminary computational results from this model show a slightly asymmetric temperature distribution at the reactor center line with a 1000 sccm argon flow at 850°C reactor temperature. Both these experimental and computational modeling studies have identified key criteria for the prototype reactor being designed for bulk polysilicon growth.

  10. Internal shear cracking in bulk metal forming

    DEFF Research Database (Denmark)

    Christiansen, Peter; Nielsen, Chris Valentin; Bay, Niels Oluf


    This paper presents an uncoupled ductile damage criterion for modelling the opening and propagation of internal shear cracks in bulk metal forming. The criterion is built upon the original work on the motion of a hole subjected to shear with superimposed tensile stress triaxiality and its overall...... performance is evaluated by means of side-pressing formability tests in Aluminium AA2007-T6 subjected to different levels of pre-strain. Results show that the new proposed criterionis able to combine simplicity with efficiency for predicting the onset of fracture and the crack propagation path for the entire...... cracking to internal cracks formed undert hree-dimensional states of stress that are typical of bulk metal forming....

  11. Microfabricated bulk wave acoustic bandgap device (United States)

    Olsson, Roy H.; El-Kady, Ihab F.; McCormick, Frederick; Fleming, James G.; Fleming, Carol


    A microfabricated bulk wave acoustic bandgap device comprises a periodic two-dimensional array of scatterers embedded within the matrix material membrane, wherein the scatterer material has a density and/or elastic constant that is different than the matrix material and wherein the periodicity of the array causes destructive interference of the acoustic wave within an acoustic bandgap. The membrane can be suspended above a substrate by an air or vacuum gap to provide acoustic isolation from the substrate. The device can be fabricated using microelectromechanical systems (MEMS) technologies. Such microfabricated bulk wave phononic bandgap devices are useful for acoustic isolation in the ultrasonic, VHF, or UHF regime (i.e., frequencies of order 1 MHz to 10 GHz and higher, and lattice constants of order 100 .mu.m or less).

  12. Multilayer Integrated Film Bulk Acoustic Resonators

    CERN Document Server

    Zhang, Yafei


    Multilayer Integrated Film Bulk Acoustic Resonators mainly introduces the theory, design, fabrication technology and application of a recently developed new type of device, multilayer integrated film bulk acoustic resonators, at the micro and nano scale involving microelectronic devices, integrated circuits, optical devices, sensors and actuators, acoustic resonators, micro-nano manufacturing, multilayer integration, device theory and design principles, etc. These devices can work at very high frequencies by using the newly developed theory, design, and fabrication technology of nano and micro devices. Readers in fields of IC, electronic devices, sensors, materials, and films etc. will benefit from this book by learning the detailed fundamentals and potential applications of these advanced devices. Prof. Yafei Zhang is the director of the Ministry of Education’s Key Laboratory for Thin Films and Microfabrication Technology, PRC; Dr. Da Chen was a PhD student in Prof. Yafei Zhang’s research group.

  13. A large-scale biomass bulk terminal


    Wu, M.R.


    This research explores the possibility of a large-scale bulk terminal in West Europe dedicated to handle solid and liquid biomass materials. Various issues regarding the conceptual design of such a terminal have been investigated and demonstrated in this research: the potential biomass materials that will be the major international trade flows in the future, the characteristics of these potential biomass materials, the interaction between the material properties and terminal equipment, the pe...

  14. Raman characterization of bulk ferromagnetic nanostructured graphite

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, Helena, E-mail: [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay); Divine Khan, Ngwashi [Mantfort University, Leicester (United Kingdom); Faccio, Ricardo [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay); Araujo-Moreira, F.M. [Grupo de Materiais e Dispositivos-CMDMC, Departamento de Fisica e Engenharia Fisica, UFSCar, Caixa Postal 676, 13565-905, Sao Carlos SP (Brazil); Fernandez-Werner, Luciana [Centro NanoMat, Polo Tecnologico de Pando, Facultad de Quimica, Universidad de la Republica, Cno. Aparicio Saravia s/n, 91000, Pando, Canelones (Uruguay); Crystallography, Solid State and Materials Laboratory (Cryssmat-Lab), DETEMA, Facultad de Quimica, Universidad de la Republica, Gral. Flores 2124, P.O. Box 1157, Montevideo (Uruguay)


    Raman spectroscopy was used to characterize bulk ferromagnetic graphite samples prepared by controlled oxidation of commercial pristine graphite powder. The G:D band intensity ratio, the shape and position of the 2D band and the presence of a band around 2950 cm{sup -1} showed a high degree of disorder in the modified graphite sample, with a significant presence of exposed edges of graphitic planes as well as a high degree of attached hydrogen atoms.

  15. Depleted Bulk Heterojunction Colloidal Quantum Dot Photovoltaics

    KAUST Repository

    Barkhouse, D. Aaron R.


    The first solution-processed depleted bulk heterojunction colloidal quantum dot solar cells are presented. The architecture allows for high absorption with full depletion, thereby breaking the photon absorption/carrier extraction compromise inherent in planar devices. A record power conversion of 5.5% under simulated AM 1.5 illumination conditions is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Longitudinal bulk a coustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja


    Design, fabrication and characterization, in terms of mass sensitivity, is presented for a polycrystalline silicon longitudinal bulk acoustic cantilever. The device is operated in air at 51 MHz, resulting in a mass sensitivity of 100 HZ/fg (1 fg = 10{su−15 g). The initial characterization...... is conducted by depositing a minute mass by means of focused ion beam. The total noise in the currently applied measurement system allows for a mass resolution of 0.4 fg in air....

  17. Scaling Bulk Data Analysis with Mapreduce (United States)


    Writing Bulk_Extractor MapReduce 101 List of References 105 viii Initial Distribution List 113 ix THIS PAGE INTENTIONALLY LEFT BLANK x List of Figures...dedicated Experts -Formal definition presented -Large technology growth
 -Everyone has email, cell phones, networks Adolescence
 -Growth in Academics ...period is where we see those requirements come to fruition with an explosive growth into the academic community. This period marks a point where research

  18. An Extended Hardness Limit in Bulk Nanoceramics (United States)


    to fabricate bulk, fully dense and high-purity nanocrystalline ceramics with unprecedentedly small nanometer- sized grains. Using magnesium aluminate ...nanocrystalline ceramic sintered at 2 GPa and 795 C. The diffraction peaks correspond to stoichiometric magnesium aluminate [42] and a nickel ring that found to be 3.6005 ± 0.0079 g cm3, which is equal to that of stoichiometric magnesium aluminate [43] and reveals that the produced ceramics are

  19. Spiders (Araneae) Found in Bananas and Other International Cargo Submitted to North American Arachnologists for Identification. (United States)

    Vetter, Richard S; Crawford, Rodney L; Buckle, Donald J


    Spiders found in international cargo brought into North America are sometimes submitted to arachnologists for identification. Often, these spiders are presumed to be of medical importance because of size or a submitter's familiarity with a toxic spider genus from the continent of origin. Starting in 2006, requests were made for spiders found in international cargo brought into North America, in addition to the specimens from similar cargo shipments already in our museum collections. This was an ad hoc study that allowed us to focus on spiders of concern to the discoverer. We identified 135 spiders found in international cargo. A key for the most common species is provided. The most frequently submitted spiders were the pantropical huntsman spider, Heteropoda venatoria (L.) (Sparassidae), and the redfaced banana spider, Cupiennius chiapanensis Medina Soriano (Ctenidae). Spiders of medical importance were rare. The most common cargo from which spiders were submitted was bananas with most specimens coming from Central America, Ecuador, or Colombia. Lack of experience with nonnative fauna caused several experienced American arachnologists to misidentify harmless ctenid spiders (C. chiapanensis, spotlegged banana spider, Cupiennius getazi Simon) as highly toxic Phoneutria spiders. These misidentifications could have led to costly, unwarranted prophylactic eradication measures, unnecessary employee health education, heightened employee anxiety and spoilage when perishable goods are left unloaded due to safety concerns. © 2014 Entomological Society of America.

  20. Structural basis of cargo membrane protein discrimination by the human COPII coat machinery

    Energy Technology Data Exchange (ETDEWEB)

    Mancias, Joseph D.; Goldberg, Jonathan (MSKCC)


    Genomic analysis shows that the increased complexity of trafficking pathways in mammalian cells involves an expansion of the number of SNARE, Rab and COP proteins. Thus, the human genome encodes four forms of Sec24, the cargo selection subunit of the COPII vesicular coat, and this is proposed to increase the range of cargo accommodated by human COPII-coated vesicles. In this study, we combined X-ray crystallographic and biochemical analysis with functional assays of cargo packaging into COPII vesicles to establish molecular mechanisms for cargo discrimination by human Sec24 subunits. A conserved IxM packaging signal binds in a surface groove of Sec24c and Sec24d, but the groove is occluded in the Sec24a and Sec24b subunits. Conversely, LxxLE class transport signals and the DxE signal of VSV glycoprotein are selectively bound by Sec24a and Sec24b subunits. A comparative analysis of crystal structures of the four human Sec24 isoforms establishes the structural determinants for discrimination among these transport signals, and provides a framework to understand how an expansion of coat subunits extends the range of cargo proteins packaged into COPII-coated vesicles.

  1. Inter-Golgi transport mediated by COPI-containing vesicles carrying small cargoes (United States)

    Pellett, Patrina A; Dietrich, Felix; Bewersdorf, Jörg; Rothman, James E; Lavieu, Grégory


    A core prediction of the vesicular transport model is that COPI vesicles are responsible for trafficking anterograde cargoes forward. In this study, we test this prediction by examining the properties and requirements of inter-Golgi transport within fused cells, which requires mobile carriers in order for exchange of constituents to occur. We report that both small soluble and membrane-bound secretory cargo and exogenous Golgi resident glycosyl-transferases are exchanged between separated Golgi. Large soluble aggregates, which traverse individual stacks, do not transfer between Golgi, implying that small cargoes (which can fit in a typical transport vesicle) are transported by a different mechanism. Super-resolution microscopy reveals that the carriers of both anterograde and retrograde cargoes are the size of COPI vesicles, contain coatomer, and functionally require ARF1 and coatomer for transport. The data suggest that COPI vesicles traffic both small secretory cargo and steady-state Golgi resident enzymes among stacked cisternae that are stationary. DOI: PMID:24137546

  2. The iTRAPs: guardians of synaptic vesicle cargo retrieval during endocytosis

    Directory of Open Access Journals (Sweden)

    Sarah Louise Gordon


    Full Text Available The reformation of synaptic vesicles during endocytosis is essential for the maintenance of neurotransmission in central nerve terminals. Newly formed synaptic vesicles must be generated with the correct protein cargo in the correct stoichiometry to be functional for exocytosis. Classical clathrin adaptor protein complexes play a key role in sorting and clustering synaptic vesicle cargo in this regard. However it is becoming increasingly apparent that additional fail-safe mechanisms exist to ensure the accurate retrieval of essential cargo molecules. For example, the monomeric adaptor proteins AP180/CALM and stonin-2 are required for the efficient retrieval of synaptobrevin II and synaptotagmin-1 respectively. Furthermore, recent studies have revealed that synaptobrevin II and synaptotagmin-1 interact with other synaptic vesicle cargoes to ensure a high fidelity of retrieval. These cargoes are synaptophysin (for synaptobrevin II and SV2A (for synaptotagmin-1. In this review we summarise current knowledge regarding the retrieval mechanisms for both synaptobrevin II and synaptotagmin-1 during endocytosis. We also define and set criteria for a new functional group of synaptic vesicle molecules that facilitate the retrieval of their interaction partners. We have termed these molecules intrinsic trafficking partners (iTRAPs and we discuss how the function of this group impacts on presynaptic performance in both health and disease.

  3. Tailoring Magnetic Properties in Bulk Nanostructured Solids (United States)

    Morales, Jason Rolando

    Important magnetic properties and behaviors such as coercivity, remanence, susceptibility, energy product, and exchange coupling can be tailored by controlling the grain size, composition, and density of bulk magnetic materials. At nanometric length scales the grain size plays an increasingly important role since magnetic domain behavior and grain boundary concentration determine bulk magnetic behavior. This has spurred a significant amount of work devoted to developing magnetic materials with nanometric features (thickness, grain/crystallite size, inclusions or shells) in 0D (powder), 1D (wires), and 2D (thin films) materials. Large 3D nanocrystalline materials are more suitable for many applications such as permanent magnets, magneto-optical Faraday isolators etc. Yet there are relatively few successful demonstrations of 3D magnetic materials with nanoscale influenced properties available in the literature. Making dense 3D bulk materials with magnetic nanocrystalline microstructures is a challenge because many traditional densification techniques (HIP, pressureless sintering, etc.) move the microstructure out of the "nano" regime during densification. This dissertation shows that the Current Activated Pressure Assisted Densification (CAPAD) method, also known as spark plasma sintering, can be used to create dense, bulk, magnetic, nanocrystalline solids with varied compositions suited to fit many applications. The results of my research will first show important implications for the use of CAPAD for the production of exchange-coupled nanocomposite magnets. Decreases in grain size were shown to have a significant role in increasing the magnitude of exchange bias. Second, preferentially ordered bulk magnetic materials were produced with highly anisotropic material properties. The ordered microstructure resulted in changing magnetic property magnitudes (ex. change in coercivity by almost 10x) depending on the relative orientation (0° vs. 90°) of an externally

  4. Variable actin dynamics requirement for the exit of different cargo from the trans-Golgi network. (United States)

    Lázaro-Diéguez, Francisco; Colonna, Cecilia; Cortegano, Miguel; Calvo, María; Martínez, Susana E; Egea, Gustavo


    Efficient post-Golgi trafficking depends on microtubules, but actin filaments and actin-associated proteins are also postulated. Here we examined, by inverse fluorescence recovery after photobleaching, the role of actin dynamics in the exit from the TGN of fluorescent-tagged apical or basolateral and raft or non-raft-associated cargoes. Either the actin-stabilizing jasplakinolide or the actin-depolymerising latrunculin B variably but significantly inhibited post-Golgi traffic of non-raft associated apical p75NTR and basolateral VSV-G cargoes. The TGN-exit of the apical-destined VSV-G mutant was impaired only by latrunculin B. Strikingly, the raft-associated GPI-anchor protein was not affected by either actin toxin. Results indicate that actin dynamics participates in the TGN egress of both apical- and basolateral-targeted proteins but is not needed for apical raft-associated cargo.

  5. Electrostatic assembly/disassembly of nanoscaled colloidosomes for light-triggered cargo release. (United States)

    Li, Song; Moosa, Basem A; Croissant, Jonas G; Khashab, Niveen M


    Colloidosome capsules possess the potential for the encapsulation and release of molecular and macromolecular cargos. However, the stabilization of the colloidosome shell usually requires an additional covalent crosslinking which irreversibly seals the capsules, and greatly limits their applications in large-cargos release. Herein we report nanoscaled colloidosomes designed by the electrostatic assembly of organosilica nanoparticles (NPs) with oppositely charged surfaces (rather than covalent bonds), arising from different contents of a bridged nitrophenylene-alkoxysilane [NB; 3-nitro-N-(3-(triethoxysilyl)propyl)-4-(((3-(triethoxysilyl)propyl)-amino)methyl)benzamid] derivative in the silica. The surface charge of the positively charged NPs was reversed by light irradiation because of a photoreaction in the NB moieties, which impacted the electrostatic interactions between NPs and disassembled the colloidosome nanosystems. This design was successfully applied for the encapsulation and light-triggered release of cargos. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Cargo transport by sea and road - Technical and economical environmental factors

    DEFF Research Database (Denmark)

    Kristensen, Hans Otto Holmegaard


    representative relationships between the cargo capacity and the ships main dimensions. On this basis, it has been possible to calculate the necessary propulsive power by using well-established empirical power prediction methods (Guldhammer and Harvald (19 74), Oossanen (1980), and Insel & Molland (1992......)). >> By combining the statistical analysis with a subsequent power prediction, it has been possible to develop a method which can calculate the energy consumption as a function of only 3 general parameters, namely the size of the ship (more precisely the capacity), the ship's speed and the average cargo utilization...... transport will also be presented focusing on the energy demand and exhaust emissions per transport unit, i.e. per ton cargo per km. >>) Finally, the energy and emission data will be used for an economical evaluation of sea transport versus land transport. This will be done by calculating the external costs...

  7. Automated X-ray image analysis for cargo security: Critical review and future promise. (United States)

    Rogers, Thomas W; Jaccard, Nicolas; Morton, Edward J; Griffin, Lewis D


    We review the relatively immature field of automated image analysis for X-ray cargo imagery. There is increasing demand for automated analysis methods that can assist in the inspection and selection of containers, due to the ever-growing volumes of traded cargo and the increasing concerns that customs- and security-related threats are being smuggled across borders by organised crime and terrorist networks. We split the field into the classical pipeline of image preprocessing and image understanding. Preprocessing includes: image manipulation; quality improvement; Threat Image Projection (TIP); and material discrimination and segmentation. Image understanding includes: Automated Threat Detection (ATD); and Automated Contents Verification (ACV). We identify several gaps in the literature that need to be addressed and propose ideas for future research. Where the current literature is sparse we borrow from the single-view, multi-view, and CT X-ray baggage domains, which have some characteristics in common with X-ray cargo.

  8. Solar-electric-propulsion cargo vehicles for split/sprint Mars mission (United States)

    Callaghan, Christopher E.; Crowe, Michael D.; Swis, Matthew J.; Mickney, Marcus R.; Montgomery, C. Keith; Walters, Robert; Thoden, Scott


    In support of the proposed exploration of Mars, an unmanned cargo ferry SEMM1 (Solar Electric Mars Mission) was designed. The vehicle is based on solar electric propulsion, and required to transport a cargo of 61,000 kg. The trajectory is a combination of spirals; first, out from LEO, then around the sun, then spiral down to low Mars orbit. The spacecraft produces 3.03 MWe power using photovoltaic flexible blanket arrays. Ion thrusters using argon as a propellant were selected to drive the ship, providing about 60 Newtons of thrust in low Earth orbit. The configuration is based on two long truss beams to which the 24 individual, self-deployable, solar arrays are attached. The main body module supports the two beams and houses the computers, electrical, and control equipment. The thruster module is attached to the rear of the main body, and the cargo to the front.

  9. Electrostatic assembly/disassembly of nanoscaled colloidosomes for light-triggered cargo release

    KAUST Repository

    Li, Song


    Colloidosome capsules possess the potential for the encapsulation and release of molecular and macromolecular cargos. However, the stabilization of the colloidosome shell usually requires an additional covalent crosslinking which irreversibly seals the capsules, and greatly limits their applications in large-cargos release. Herein we report nanoscaled colloidosomes designed by the electrostatic assembly of organosilica nanoparticles (NPs) with oppositely charged surfaces (rather than covalent bonds), arising from different contents of a bridged nitrophenylene-alkoxysilane [NB; 3-nitro-N-(3-(triethoxysilyl)propyl)-4-(((3-(triethoxysilyl)propyl)-amino)methyl)benzamid] derivative in the silica. The surface charge of the positively charged NPs was reversed by light irradiation because of a photoreaction in the NB moieties, which impacted the electrostatic interactions between NPs and disassembled the colloidosome nanosystems. This design was successfully applied for the encapsulation and light-triggered release of cargos. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Synthesis and characterization of nanowire coils of organometallic coordination polymers for controlled cargo release. (United States)

    Liang, Guodong; Ni, Huan; Bao, Suping; Zhu, Fangming; Gao, Haiyang; Wu, Qing


    Nanowire coils of organometallic coordination polymers have been synthesized for the first time by using the emulsion periphery polymerization technique. An amphiphilic triblock copolymer terminated with inclusion complex of β-cyclodextrin and 4,4'-bipyridine self-assembles into oil-in-water emulsion in a toluene/water mixture. Subsequent coordination of bipyridine with Ni(II) in periphery of emulsions results in the formation of coordination polymer nanowire coils. The nanowire coils are composed of nanowires with diameter of 2 nm. Nanowire coils exhibit enhanced thermal stability in contrast to their parent triblock copolymer. Interestingly, nanowire coils are capable of encapsulating organic cargoes. Encapsulated cargoes can be selectively extracted from nanowire coils without damaging nanowire coils. Nanowire coils are potential candidates for encapsulating and controlled release of organic cargoes.


    Directory of Open Access Journals (Sweden)


    Full Text Available The controllability of military transport aircraft deteriorates at heavy single piece landing. To solve this problem and a specific methodology for pilotage of the pre-emption, and automation tools are being developed. Preliminary study ofpilotage technique and authomatic control algorythm demand a reliable mathematical model of aircraft dynamics at cargo item drop. Such model should take into account significant change in the position of the aircraft center of mass and aircraft inertia tensor. Simplified models were based on modeling the movement of the center of mass and rotation around the cen- ter of mass of the aircraft. Such models do not take into account the inertial forces and moments of moving a cargo item. This circumstance does not allow to obtain reliable results in the simulation. The article presents the description of the complete mathematical model of the movement of military transport aircraft in landing of a cargo item. Examines the com- plex material system of solids and a detailed description of the properties of its components. The equations of motion of the aircraft as a system carrier (aircraft without a cargo item and wear (of moving a cargo item bodies to reflect the changes in the inertia tensor. The functioning of the power plant, steering actuators, flight control system, an exhaust chute, the sen- sors of the primary information are taken into account. The equations of motion for systems of bodies projected on the air- craft reference plane are being recorded. This approach takes into account changes of the inertia tensor and the position of the main central axes of inertia in the process of landing of a cargo item. It allows us to simulate the condition of the air- craft at all speeds of the pitch, normal overload, and masses of single piece and placement, as evidenced by the high con- vergence of modeling results with data from flight tests.

  12. A Benchmarking of Operational Efficiency in Asia Pacific International Cargo Airports

    Directory of Open Access Journals (Sweden)

    Tae-won Chung


    Full Text Available This paper compares operational efficiency of major cargo airports in the Asia Pacific region. The multi-dimensional scaling cluster analysis by R-square method was used as the benchmarking tool to provide airport management with a means to examine various aspects of their operational efficiency against those of other airports. Ten operational efficiency factors for the clustering and efficiency estimation of airports in the Asia Pacific region were used in a regression model to overcome the complexity of multi-dimensional scaling approach. The resulting classification is used to identify the efficiency benchmarks of leading air cargo airports which have implications for Incheon airport in Korea.


    Directory of Open Access Journals (Sweden)

    Maria CIEŚLA


    Full Text Available This paper presents the problem of improper security of cargo in trucks as the cause of about 25% of the accidents that takes place in road transport. Attention was drawn to aspects of legal liability for errors resulting from incorrect load securing according to polish law. Article was enriched with practical examples illustrating the effects of improper cargo securing on transport unit and shows how it had to be prepared properly. When planning the proper transport protection of metal sheets rolled both calculation methods and computer applications were used.

  14. Automatic air cargo selection and weight balancing: A mixed integer programming approach


    Vancroonenburg, Wim; Verstichel, Jannes; Tavernier, Karel; Vanden Berghe, Greet


    The present contribution introduces a mixed integer linear programming model as a decision support tool for air cargo load planning. The main objective for the model is to find the most profitable selection from a set of cargo to be loaded on an aircraft. The secondary objective is to minimize the deviation between the aircraft’s centre of gravity, and a known target value so as to reduce fuel consumption and improve stability. The model is subject to a large number of constraints that ensure...

  15. Massively parallel delivery of large cargo into mammalian cells with light pulses. (United States)

    Wu, Yi-Chien; Wu, Ting-Hsiang; Clemens, Daniel L; Lee, Bai-Yu; Wen, Ximiao; Horwitz, Marcus A; Teitell, Michael A; Chiou, Pei-Yu


    We report a high-throughput platform for delivering large cargo elements into 100,000 cells in 1 min. Our biophotonic laser-assisted surgery tool (BLAST) generates an array of microcavitation bubbles that explode in response to laser pulsing, forming pores in adjacent cell membranes through which cargo is gently driven by pressurized flow. The platform delivers large items including bacteria, enzymes, antibodies and nanoparticles into diverse cell types with high efficiency and cell viability. We used this platform to explore the intracellular lifestyle of Francisella novicida and discovered that the iglC gene is unexpectedly required for intracellular replication even after phagosome escape into the cell cytosol.

  16. Use of ABC–XYZ–analysis in cost management of the cargo turnover in transport logistics


    Chukurna O.; Davydova A.


    This article focuses on the relevance of the use of ABC–XYZ–analysis in the management of cargo turnover costs in the implementation of transport and logistics operations. It proposed by using the ABC analysis to rank suppliers or customers of freight turnover and the cost of each logistics operation (or profitability of the logistics services). On the basis of the received data to optimise logistics costs. It is proposed to use the XYZ–analysis to predict the volume of cargo turnover and a l...

  17. Air cargo: An Integrated Systems View. 1978 Summer Faculty Fellowship Program in Engineering Systems Design (United States)

    Keaton, A. (Editor); Eastman, R. (Editor); Hargrove, A. (Editor); Rabiega, W. (Editor); Olsen, R. (Editor); Soberick, M. (Editor)


    The national air cargo system is analyzed and how it should be in 1990 is prescribed in order to operate successfully through 2015; that is through one equipment cycle. Elements of the system which are largely under control of the airlines and the aircraft manufacturers are discussed. The discussion deals with aircraft, networks, facilities, and procedures. The regulations which govern the movement of air freight are considered. The larger public policy interests which must be served by the kind of system proposed, the air cargo integrated system (ACIS), are addressed. The possible social, economical, political, and environment impacts of the system are considered. Recommendations are also given.

  18. Walking to work: roles for class V myosins as cargo transporters. (United States)

    Hammer, John A; Sellers, James R


    Cells use molecular motors, such as myosins, to move, position and segregate their organelles. Class V myosins possess biochemical and structural properties that should make them ideal actin-based cargo transporters. Indeed, studies show that class V myosins function as cargo transporters in yeast, moving a range of organelles, such as the vacuole, peroxisomes and secretory vesicles. There is also increasing evidence in vertebrate cells that class V myosins not only tether organelles to actin but also can serve as short-range, point-to-point organelle transporters, usually following long-range, microtubule-dependent organelle transport.

  19. An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor (United States)

    Dagdas, Yasin F; Belhaj, Khaoula; Maqbool, Abbas; Chaparro-Garcia, Angela; Pandey, Pooja; Petre, Benjamin; Tabassum, Nadra; Cruz-Mireles, Neftaly; Hughes, Richard K; Sklenar, Jan; Win, Joe; Menke, Frank; Findlay, Kim; Banfield, Mark J; Kamoun, Sophien; Bozkurt, Tolga O


    Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds host autophagy protein ATG8CL to stimulate autophagosome formation. PexRD54 depletes the autophagy cargo receptor Joka2 out of ATG8CL complexes and interferes with Joka2's positive effect on pathogen defense. Thus, a plant pathogen effector has evolved to antagonize a host autophagy cargo receptor to counteract host defenses. DOI: PMID:26765567

  20. Protocells and their use for targeted delivery of multicomponent cargos to cancer cells (United States)

    Brinker, C Jeffrey; Ashley, Carlee Erin; Jiang, Xingmao; Liu, Juewen; Peabody, David S; Wharton, Walker Richard; Carnes, Eric; Chackerian, Bryce; Willman, Cheryl L


    Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to the porous particle core to form a protocell. The lipid bilayer can be modified with targeting ligands or other ligands to achieve targeted delivery of cargo components that are loaded within the protocell to a target cell, e.g., a type of cancer. Shielding materials can be conjugated to the surface of the lipid bilayer to reduce undesired non-specific binding.

  1. 46 CFR Table 2 to Part 153 - Cargoes Not Regulated Under Subchapters D or O of This Chapter When Carried in Bulk on Non... (United States)


    ... hydroxyethylethylenediamine triacetic acid, trisodium salt solution D Fish solubles (water based fish meal extracts) III... Category 2-Amino-2-hydroxymethyl-1,3-propanediol solution III Ammonium hydrogen phosphate solution D... pentaacetic acid, pentasodium salt solution III 1,4-Dihydro-9,10-dihydroxy anthracene, disodium salt solution...

  2. Materials for Bulk Acoustic Resonators and Filters (United States)

    Loebl, Hans-Peter


    Highly selective solidly mounted bulk acoustic wave (BAW) band pass filters are suited for mobile and wireless systems in the GHz frequency range between 0.8 and 10 GHz. Electro-acoustic thin film BAW resonators are the building blocks these BAW filters. Piezoelectric materials used in these resonators include mainly AlN or ZnO which can be deposited by dedicated thin film sputter deposition techniques. Using these piezo-electric materials and using suited materials for the acoustic Bragg reflector, BAW resonators with high quality factors can be fabricated. The achievable filter bandwidth is approximately 4Alternatively, also ferroelectric thin films might be used to achieve higher coupling coefficient and thus filter bandwidth. BAW resonators and filters have been designed and fabricated on 6" Silicon and glass wafers. Results are presented for resonators and filters operating between 1.95 and 8 GHz. The talk will give an overview of the material aspects which are important for BAW devices. It will be shown that modeling of the resonator and filter response using 1D electro-acoustic simulation (1,2) which includes losses is essential to extract acoustic and electrical material parameters. (1) Solidly Mounted Bulk Acoustic Wave Filters for the Ghz Frequency Range, H.P. Loebl, C. Metzmacher , D.N.Peligrad , R. Mauczok , M. Klee , W. Brand , R.F. Milsom , P.Lok , F.van Straten , A. Tuinhout , J.W.Lobeek, IEEE 2002 Ultrasonics Symposium Munich, October 2002. (2) Combined Acoustic-Electromagnetic Simulation Of Thin-Film Bulk Acoustic Wave Filters, R.F. Milsom, H-P. Löbl, D.N. Peligrad, J-W. Lobeek, A. Tuinhout, R. H. ten Dolle IEEE 2002 Ultrasonics Symposium Munich, October 2002.

  3. Extraordinary plasticity of ductile bulk metallic glasses. (United States)

    Chen, Mingwei; Inoue, Akihisa; Zhang, Wei; Sakurai, Toshio


    Shear bands generally initiate strain softening and result in low ductility of metallic glasses. In this Letter, we report high-resolution electron microscope observations of shear bands in a ductile metallic glass. Strain softening caused by localized shearing was found to be effectively prevented by nanocrystallization that is in situ produced by plastic flow within the shear bands, leading to large plasticity and strain hardening. These atomic-scale observations not only well explain the extraordinary plasticity that was recently observed in some bulk metallic glasses, but also reveal a novel deformation mechanism that can effectively improve the ductility of monolithic metallic glasses.

  4. "Work-Hardenable" ductile bulk metallic glass. (United States)

    Das, Jayanta; Tang, Mei Bo; Kim, Ki Buem; Theissmann, Ralf; Baier, Falko; Wang, Wei Hua; Eckert, Jürgen


    Usually, monolithic bulk metallic glasses undergo inhomogeneous plastic deformation and exhibit poor ductility (glass, which exhibits high strength of up to 2265 MPa together with extensive "work hardening" and large ductility of 18%. Significant increase in the flow stress was observed during deformation. The "work-hardening" capability and ductility of this class of metallic glass is attributed to a unique structure correlated with atomic-scale inhomogeneity, leading to an inherent capability of extensive shear band formation, interactions, and multiplication of shear bands.

  5. Multiphase composites with extremal bulk modulus

    DEFF Research Database (Denmark)

    Gibiansky, L. V.; Sigmund, Ole


    This paper is devoted to the analytical and numerical study of isotropic elastic composites made of three or more isotropic phases. The ranges of their effective bulk and shear moduli are restricted by the Hashin-Shtrikman-Walpole (HSW) bounds. For two-phase composites, these bounds are attainabl...... isotropic three-dimensional three-phase composites with cylindrical inclusions of arbitrary cross-sections (plane strain problem) or transversely isotropic thin plates (plane stress or bending of plates problems). (C) 2000 Elsevier Science Ltd. All rights reserved....

  6. Towards bulk based preconditioning for quantum dotcomputations

    Energy Technology Data Exchange (ETDEWEB)

    Dongarra, Jack; Langou, Julien; Tomov, Stanimire; Channing,Andrew; Marques, Osni; Vomel, Christof; Wang, Lin-Wang


    This article describes how to accelerate the convergence of Preconditioned Conjugate Gradient (PCG) type eigensolvers for the computation of several states around the band gap of colloidal quantum dots. Our new approach uses the Hamiltonian from the bulk materials constituent for the quantum dot to design an efficient preconditioner for the folded spectrum PCG method. The technique described shows promising results when applied to CdSe quantum dot model problems. We show a decrease in the number of iteration steps by at least a factor of 4 compared to the previously used diagonal preconditioner.

  7. Improving the bulk data transfer experience

    Energy Technology Data Exchange (ETDEWEB)

    Guok, Chin; Guok, Chin; Lee, Jason R.; Berket, Karlo


    Scientific computations and collaborations increasingly rely on the network to provide high-speed data transfer, dissemination of results, access to instruments, support for computational steering, etc. The Energy Sciences Network is establishing a science data network to provide user driven bandwidth allocation. In a shared network environment, some reservations may not be granted due to the lack of available bandwidth on any single path. In many cases, the available bandwidth across multiple paths would be sufficient to grant the reservation. In this paper we investigate how to utilize the available bandwidth across multiple paths in the case of bulk data transfer.

  8. Binary Ni-Nb bulk metallic glasses (United States)

    Xia, L.; Li, W. H.; Fang, S. S.; Wei, B. C.; Dong, Y. D.


    We studied the glass forming ability of Ni-Nb binary alloys and found that some of the alloys can be prepared into bulk metallic glasses by a conventional Cu-mold casting. The best glass former within the compositional range studied is off-eutectic Ni62Nb38 alloy, which is markedly different from those predicted by the multicomponent and deep eutectic rules. The glass formation mechanism for binary Ni-Nb alloys was studied from the thermodynamic point of view and a parameter γ* was proposed to approach the ability of glass formation against crystallization.

  9. Cosmological Brane World Solutions with Bulk Scalar Fields


    Davis, Stephen C.


    Cosmological brane world solutions are found for five-dimensional bulk spacetimes with a scalar field. A supergravity inspired method for obtaining static solutions is combined with a method for finding brane cosmologies with constant bulk energies. This provides a way to generate full (bulk and brane) cosmological solutions to brane worlds with bulk scalar fields. Examples of these solutions, and their cosmological evolution, are discussed.

  10. 78 FR 23946 - Extension of the Air Cargo Advance Screening (ACAS) Pilot Program and Reopening of Application... (United States)


    ... SECURITY U.S. Customs and Border Protection Extension of the Air Cargo Advance Screening (ACAS) Pilot... that CBP is formalizing and expanding the ACAS pilot to include other eligible participants in the air... advance information for air cargo. The results of the ACAS pilot will help determine the relevant data...

  11. 46 CFR 154.1836 - Vapor venting as a means of cargo tank pressure and temperature control. (United States)


    ... LIQUEFIED GASES Operations § 154.1836 Vapor venting as a means of cargo tank pressure and temperature... temperature control. 154.1836 Section 154.1836 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... cargo pressure and temperature control system under §§ 154.701 through 154.709 is operating and that...

  12. 49 CFR 393.100 - Which types of commercial motor vehicles are subject to the cargo securement standards of this... (United States)


    ... AND ACCESSORIES NECESSARY FOR SAFE OPERATION Protection Against Shifting and Falling Cargo § 393.100... trucks, truck tractors, semitrailers, full trailers, and pole trailers. (b) Prevention against loss of..., spilling, blowing or falling from the motor vehicle. (c) Prevention against shifting of load. Cargo must be...

  13. 19 CFR 151.24 - Unlading facilities for bulk sugar. (United States)


    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Unlading facilities for bulk sugar. 151.24 Section... OF THE TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Sugars, Sirups, and Molasses § 151.24 Unlading facilities for bulk sugar. When dutiable sugar is to be imported in bulk, a full...

  14. Use of containers to carry bulk and break bulk commodities and its impact on gulf region ports and international trade. (United States)


    The University of New Orleans Transportation Institute was tasked by the Louisiana Transportation Research Center (LTRC) in mid-2012 to assess the use of containers to transport bulk and break bulk commodities and to determine what their impact would...

  15. Bulk magnetic domain stability controls paleointensity fidelity (United States)

    Paterson, Greig A.; Muxworthy, Adrian R.; Yamamoto, Yuhji; Pan, Yongxin


    Nonideal, nonsingle-domain magnetic grains are ubiquitous in rocks; however, they can have a detrimental impact on the fidelity of paleomagnetic records—in particular the determination of ancient magnetic field strength (paleointensity), a key means of understanding the evolution of the earliest geodynamo and the formation of the solar system. As a consequence, great effort has been expended to link rock magnetic behavior to paleointensity results, but with little quantitative success. Using the most comprehensive rock magnetic and paleointensity data compilations, we quantify a stability trend in hysteresis data that characterizes the bulk domain stability (BDS) of the magnetic carriers in a paleomagnetic specimen. This trend is evident in both geological and archeological materials that are typically used to obtain paleointensity data and is therefore pervasive throughout most paleomagnetic studies. Comparing this trend to paleointensity data from both laboratory and historical experiments reveals a quantitative relationship between BDS and paleointensity behavior. Specimens that have lower BDS values display higher curvature on the paleointensity analysis plot, which leads to more inaccurate results. In-field quantification of BDS therefore reflects low-field bulk remanence stability. Rapid hysteresis measurements can be used to provide a powerful quantitative method for preselecting paleointensity specimens and postanalyzing previous studies, further improving our ability to select high-fidelity recordings of ancient magnetic fields. BDS analyses will enhance our ability to understand the evolution of the geodynamo and can help in understanding many fundamental Earth and planetary science questions that remain shrouded in controversy.

  16. Boundary-bulk relation in topological orders

    Directory of Open Access Journals (Sweden)

    Liang Kong


    Full Text Available In this paper, we study the relation between an anomaly-free n+1D topological order, which are often called n+1D topological order in physics literature, and its nD gapped boundary phases. We argue that the n+1D bulk anomaly-free topological order for a given nD gapped boundary phase is unique. This uniqueness defines the notion of the “bulk” for a given gapped boundary phase. In this paper, we show that the n+1D “bulk” phase is given by the “center” of the nD boundary phase. In other words, the geometric notion of the “bulk” corresponds precisely to the algebraic notion of the “center”. We achieve this by first introducing the notion of a morphism between two (potentially anomalous topological orders of the same dimension, then proving that the notion of the “bulk” satisfies the same universal property as that of the “center” of an algebra in mathematics, i.e. “bulk = center”. The entire argument does not require us to know the precise mathematical description of a (potentially anomalous topological order. This result leads to concrete physical predictions.

  17. Substantial bulk photovoltaic effect enhancement via nanolayering (United States)

    Wang, Fenggong; Young, Steve M.; Zheng, Fan; Grinberg, Ilya; Rappe, Andrew M.


    Spontaneous polarization and inversion symmetry breaking in ferroelectric materials lead to their use as photovoltaic devices. However, further advancement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing photocurrent. By unravelling the correlation between ferroelectric materials' responses to solar irradiation and their local structure and electric polarization landscapes, here we show from first principles that substantial bulk photovoltaic effect enhancement can be achieved by nanolayering PbTiO3 with nickel ions and oxygen vacancies ((PbNiO2)x(PbTiO3)1-x). The enhancement of the total photocurrent for different spacings between the Ni-containing layers can be as high as 43 times due to a smaller bandgap and photocurrent direction alignment for all absorption energies. This is due to the electrostatic effect that arises from nanolayering. This opens up the possibility for control of the bulk photovoltaic effect in ferroelectric materials by nanoscale engineering of their structure and composition.

  18. Perovskite oxides: Oxygen electrocatalysis and bulk structure (United States)

    Carbonio, R. E.; Fierro, C.; Tryk, D.; Scherson, D.; Yeager, Ernest


    Perovskite type oxides were considered for use as oxygen reduction and generation electrocatalysts in alkaline electrolytes. Perovskite stability and electrocatalytic activity are studied along with possible relationships of the latter with the bulk solid state properties. A series of compounds of the type LaFe(x)Ni1(-x)O3 was used as a model system to gain information on the possible relationships between surface catalytic activity and bulk structure. Hydrogen peroxide decomposition rate constants were measured for these compounds. Ex situ Mossbauer effect spectroscopy (MES), and magnetic susceptibility measurements were used to study the solid state properties. X ray photoelectron spectroscopy (XPS) was used to examine the surface. MES has indicated the presence of a paramagnetic to magnetically ordered phase transition for values of x between 0.4 and 0.5. A correlation was found between the values of the MES isomer shift and the catalytic activity for peroxide decomposition. Thus, the catalytic activity can be correlated to the d-electron density for the transition metal cations.

  19. Overview of Crane Control Systems and the Related Problems: Analysis of Container Oscillation Using Different Types of Cargoes

    Directory of Open Access Journals (Sweden)

    Tomas Eglynas


    Full Text Available Growing international trading increased cargo transportation in containers, therefore the port cranes have higher loads. Increased cargo flows can influence transportation safety. It is therefore necessary to review the crane systems and determine what factors might influence the volatility of the container and its cargo during transportation. The paper includes consideration and analysis of crane control systems and related problems. The authors consider the reasons of problems, probable damage and solution methods. The paper also provides the analysis of the relationship between different container cargoes and container oscillations occurring during handling operations using a container crane prototype. The analysis of the effect of different cargoes in containers on loading process and the results of occurring oscillations are presented.

  20. 46 CFR 150.160 - Carrying a cargo as an exception to the compatibility chart. (United States)


    ... chart. 150.160 Section 150.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN... compatibility chart. The Operator of a vessel having on board a cargo carried as an exception under § 150.150 but not listed in Appendix I, Exceptions to the Chart, shall make sure that: (a) The Commandant (G-MSO...

  1. Indications of marine bioinvasion from network theory. An analysis of the global cargo ship network

    NARCIS (Netherlands)

    Kölzsch, A.; Blasius, B.


    The transport of huge amounts of small aquatic organisms in the ballast tanks and at the hull of large cargo ships leads to ever increasing rates of marine bioinvasion. In this study, we apply a network theoretic approach to examine the introduction of invasive species into new ports by global

  2. Cargo crowding at actin-rich regions along axons causes local traffic jams. (United States)

    Sood, Parul; Murthy, Kausalya; Kumar, T Vinod; Nonet, Michael L; Menon, Gautam I; Koushika, Sandhya P


    Steady axonal cargo flow is central to the functioning of healthy neurons. However, a substantial fraction of cargo in axons remains stationary up to several minutes (Kang, Tian et al. 2008, Tang, Scott et al. 2012, Tang, Scott et al. 2013, Iacobucci, Rahman et al. 2014). We examine the transport of precursors of synaptic vesicles (pre-SVs), endosomes and mitochondria in C. elegans touch receptor neurons (TRNs), showing that stationary cargo are predominantly present at actin-rich regions along the neuronal process. Stationary vesicles at actin-rich regions increase the propensity of moving vesicles to stall at the same location, resulting in traffic jams arising from physical crowding. Such local traffic jams at actin-rich regions are likely to be a general feature of axonal transport since they also occur in Drosophila neurons. Repeated touch stimulation of C. elegans reduces the density of stationary pre-SVs, indicating that these traffic jams can act as both sources and sinks of vesicles. This suggests that vesicles trapped in actin-rich regions are functional reservoirs that may contribute to maintaining robust cargo flow in the neuron. This article is protected by copyright. All rights reserved.

  3. 49 CFR 393.106 - What are the general requirements for securing articles of cargo? (United States)


    ... concrete, sand, gravel, aggregates) and are transported in a tank, hopper, box, or similar device that...) Applicability. The rules in this section are applicable to the transportation of all types of articles of cargo... types covered by the commodity-specific rules of § 393.116 through § 393.136. The commodity-specific...

  4. 49 CFR 1544.202 - Persons and property onboard an all-cargo aircraft. (United States)


    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.202 Persons and property onboard an all... program in an all-cargo operation, must apply the security measures in its security program for persons...

  5. 19 CFR 122.48a - Electronic information for air cargo required in advance of arrival. (United States)


    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Electronic information for air cargo required in... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Aircraft Entry and Entry Documents; Electronic Manifest Requirements for Passengers, Crew Members, and Non-Crew Members Onboard...

  6. Tracking 800-year-old Shipments: An Archaeological Investigation of the Mado Shipwreck Cargo, Taean, Korea (United States)

    Kim, Minkoo; Moon, Whan Suk


    This paper examines cargo from an 800-year-old shipwreck and discusses its implications in relation to the exchange networks and maritime transportation of the Goryeo period (A.D. 918-1392) in Korea. In 2007, two local fishermen fortuitously discovered porcelain vessels from a Goryeo-period shipwreck off the mid-western coast of the Korean peninsula. Underwater excavation conducted by the National Research Institute of Maritime Cultural Heritage (NRIMCH) revealed that the ship was carrying a myriad of cargoes destined for Gaegyeong, the capital of the Goryeo dynasty. Excavation indicates that the main body of the cargo was porcelain vessels produced in the southern part of the peninsula. Archaeobotanical investigation of the wreck deposits revealed that the ship was carrying crops such as rice ( Oryza sativa L.), broomcorn millet ( Panicum miliaceum L.), foxtail millet ( Setaria italica (L.) P. Beauv.), and buckwheat ( Fagopyrum esculentum Moench) bound for the capital. Among the recovered objects were 73 wooden cargo tags with Chinese letters. These tags, equivalent to the modern day air bill, contained detailed information about the senders, recipients, and shipped goods. These findings indicate that during the Goryeo period maritime transportation played an important role in the interpersonal exchange of products over long distances.

  7. 7 CFR 318.13-10 - Inspection of baggage, other personal effects, and cargo. (United States)


    ... the airport security checkpoint or the aircraft boarding gate, at the time they pass through the checkpoint or the gate. Passengers shall offer their check-in baggage for inspection at agricultural..., manifest, or bill of lading that accompanies the consignment. (3) Cargo moved in accordance with § 318.13-6...

  8. 33 CFR 126.27 - General permit for handling dangerous cargo. (United States)


    ...: (1) Class 1, Division 1.3 and Division 1.5 (Explosive) materials, with a net explosive quantity in... of particular hazard. (c) No Class 1 (explosive) materials (as defined in 49 CFR 173.50) or other... be arranged in a manner that retards the spread of fire, such as by interspersing dangerous cargo...

  9. Cargo Revenue Management: Bid-Prices for a 0-1 Multi Knapsack Problem

    NARCIS (Netherlands)

    K. Pak; R. Dekker (Rommert)


    textabstractRevenue management is the practice of selecting those customers that generate the maximum revenue from a fixed and perishable capacity. Cargo revenue management differs from the well-known passenger revenue management problem by the fact that its capacity constraint is 2-dimensional,

  10. 19 CFR 123.92 - Electronic information for truck cargo required in advance of arrival. (United States)


    ... the cargo laden aboard the truck as contained in the bill(s) of lading (this means the quantity of the... complete name and address, or identification number, from the bill(s) of lading (for each house bill in a... which may be informally entered on Customs Form (CF) 368 or 368A (cash collection or receipt); (ii...

  11. Local synaptic signaling enhances the stochastic transport of motor-driven cargo in neurons

    KAUST Repository

    Newby, Jay


    The tug-of-war model of motor-driven cargo transport is formulated as an intermittent trapping process. An immobile trap, representing the cellular machinery that sequesters a motor-driven cargo for eventual use, is located somewhere within a microtubule track. A particle representing a motor-driven cargo that moves randomly with a forward bias is introduced at the beginning of the track. The particle switches randomly between a fast moving phase and a slow moving phase. When in the slow moving phase, the particle can be captured by the trap. To account for the possibility that the particle avoids the trap, an absorbing boundary is placed at the end of the track. Two local signaling mechanisms-intended to improve the chances of capturing the target-are considered by allowing the trap to affect the tug-of-war parameters within a small region around itself. The first is based on a localized adenosine triphosphate (ATP) concentration gradient surrounding a synapse, and the second is based on a concentration of tau-a microtubule-associated protein involved in Alzheimer\\'s disease-coating the microtubule near the synapse. It is shown that both mechanisms can lead to dramatic improvements in the capture probability, with a minimal increase in the mean capture time. The analysis also shows that tau can cause a cargo to undergo random oscillations, which could explain some experimental observations. © 2010 IOP Publishing Ltd.

  12. Endocytic Trafficking of Membrane-Bound Cargo: A Flotillin Point of View

    Directory of Open Access Journals (Sweden)

    Melanie Meister


    Full Text Available The ubiquitous and highly conserved flotillin proteins, flotillin-1 and flotillin-2, have been shown to be involved in various cellular processes such as cell adhesion, signal transduction through receptor tyrosine kinases as well as in cellular trafficking pathways. Due to the fact that flotillins are acylated and form hetero-oligomers, they constitutively associate with cholesterol-enriched lipid microdomains. In recent years, such microdomains have been appreciated as platforms that participate in endocytosis and other cellular trafficking steps. This review summarizes the current findings on the role of flotillins in membrane-bound cargo endocytosis and endosomal trafficking events. We will discuss the proposed function of flotillins in endocytosis in the light of recent findings that point towards a role for flotillins in a step that precedes the actual endocytic uptake of cargo molecules. Recent findings have also revealed that flotillins may be important for endosomal sorting and recycling of specific cargo molecules. In addition to these aspects, the cellular trafficking pathway of flotillins themselves as potential cargo in the context of growth factor signaling will be discussed.

  13. 29 CFR 1917.22 - Hazardous cargo 2 (See § 1917.2(p)). (United States)


    ... 29 Labor 7 2010-07-01 2010-07-01 false Hazardous cargo 2 (See § 1917.2(p)). 1917.22 Section 1917.22 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... § 1917.2(p)). 2 The Department of Transportation and the United States Coast Guard apply requirements...

  14. Membrane-associated cargo recycling by tubule-based endosomal sorting

    NARCIS (Netherlands)

    van Weering, J.R.T.; Cullen, P.J.


    The endosome system is a collection of organelles that sort membrane-associated proteins and lipids for lysosomal degradation or recycling back to their target organelle. Recycling cargo is captured in a network of membrane tubules emanating from endosomes where tubular carriers pinch off. These

  15. Injuries sustained by passengers travelling in the cargo area of light ...

    African Journals Online (AJOL)

    Introduction. Despite its inherently dangerous nature, the practice of transporting passengers in the cargo area of light delivery vehicles (LDVs) is widespread in South Africa. Objective. To review the patterns and outcome of injuries associated with events involving LDVs transporting passengers. Methods. All patients ...

  16. Database specification for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB)

    Energy Technology Data Exchange (ETDEWEB)

    Faby, E.Z.; Fluker, J.; Hancock, B.R.; Grubb, J.W.; Russell, D.L. [Univ. of Tennessee, Knoxville, TN (United States); Loftis, J.P.; Shipe, P.C.; Truett, L.F. [Oak Ridge National Lab., TN (United States)


    This Database Specification for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB) describes the database organization and storage allocation, provides the detailed data model of the logical and physical designs, and provides information for the construction of parts of the database such as tables, data elements, and associated dictionaries and diagrams.

  17. Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometry

    NARCIS (Netherlands)

    Snijder, Joost|info:eu-repo/dai/nl/338018328; van de Waterbeemd, Michiel|info:eu-repo/dai/nl/412537761; Damoc, Eugen; Denisov, Eduard; Grinfeld, Dmitry; Bennett, Antonette; Agbandje-McKenna, Mavis; Makarov, Alexander; Heck, Albert J R|info:eu-repo/dai/nl/105189332


    Accurate mass analysis can provide useful information on the stoichiometry and composition of protein-based particles, such as virus-like assemblies. For applications in nanotechnology and medicine, such nanoparticles are loaded with foreign cargos, making accurate mass information essential to

  18. 76 FR 5586 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo... (United States)


    ... AGENCY California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo... enforce any standard relating to the control of emissions from new motor vehicles or new motor vehicle... relating to the control of emissions from any new motor vehicle or new motor vehicle engine as condition...

  19. 75 FR 59617 - Notification of Arrival in U.S. Ports; Certain Dangerous Cargoes (United States)


    ... Oxide, Methane (LNG), Methyl Bromide, Sulfur Dioxide, and Vinyl Chloride as CDC at all times, even when... eight CDCs--anhydrous ammonia, chlorine, ethane, ethylene oxide, methane (LNG), methyl bromide, sulfur... 46 CFR 154.7 that is flammable and/or toxic and that is not carried as certain dangerous cargo...

  20. 77 FR 35993 - Agency Information Collection Activities: Cargo Container and Road Vehicle Certification for... (United States)


    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Cargo Container and Road Vehicle Certification for Transport Under Customs Seal AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: 30-Day notice and request for comments; Extension of an existing...

  1. 33 CFR 149.135 - What should be marked on the cargo transfer system alarm switch? (United States)


    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What should be marked on the cargo transfer system alarm switch? 149.135 Section 149.135 Navigation and Navigable Waters COAST GUARD... switch? Each switch for activating an alarm, and each audio or visual device for signaling an alarm, must...

  2. 76 FR 4847 - Hazardous Materials: Safety Requirements for External Product Piping on Cargo Tanks Transporting... (United States)


    ... Docket Operations Office (see ADDRESSES). Privacy Act: Anyone is able to search the electronic form of... constructed with engine, body, and cargo tank permanently mounted to the same chassis. Based on the protective... compressed air from an auxiliary tank through an air filter and regulator into the lines. The purge can be...

  3. 78 FR 57485 - Security Zone; Protection of Military Cargo, Captain of the Port Zone Puget Sound (United States)


    ... Puget Sound AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast... cargo in the navigable waters of Puget Sound and adjacent waters. Entry into this zone is prohibited... or email LTJG Johnny Zeng, Sector Puget Sound Waterways Management Division, Coast Guard; telephone...

  4. 19 CFR 122.163 - Transit air cargo traveling to U.S. ports. (United States)


    ...: (1) Shortage in delivery; (2) Irregular delivery; or (3) Non-delivery. (b) Liabilities assessed. The... cargo; and (2) Other information available to the port director relating to the same or similar merchandise. If the data or documents required by this section are not submitted within 90 days of the date...

  5. 49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks. (United States)


    ... tests required in the applicable specification or § 180.407(g)(1)(iv). (v) Any modification that changes information displayed on the specification plate requires the installation of a supplemental specification... mounting of specification cargo tanks. 180.413 Section 180.413 Transportation Other Regulations Relating to...

  6. 33 CFR 150.435 - When are cargo transfers not allowed? (United States)


    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false When are cargo transfers not allowed? 150.435 Section 150.435 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... or serving the port. ...

  7. The Cargo Cult and the Protestant Ethic as Conflicting Ideologies: Implications for Education. (United States)

    Conforti, Joseph M.


    Examines a shift in American culture away from the Protestant ethic, which emphasizes personal responsibility and effort, towards the "cargo cult," which emphasizes factors beyond individual control such as luck. Discusses the implications for education, which is based on the Protestant ideology. (FMW)

  8. 76 FR 27300 - Hazardous Materials: Cargo Tank Motor Vehicle Loading and Unloading Operations (United States)


    ... Materials: Cargo Tank Motor Vehicle Loading and Unloading Operations AGENCY: Pipeline and Hazardous..., Routing Symbol M-30, 1200 New Jersey Avenue, SE., Washington, DC 20590. Hand Delivery: To Docket...: Assess the risks of loading and unloading operations and develop written operating procedures based on...

  9. Multi-energy x-ray detectors to improve air-cargo security (United States)

    Paulus, Caroline; Moulin, Vincent; Perion, Didier; Radisson, Patrick; Verger, Loïck


    X-ray based systems have been used for decades to screen luggage or cargo to detect illicit material. The advent of energy-sensitive photon-counting x-ray detectors mainly based on Cd(Zn)Te semi-conductor technology enables to improve discrimination between materials compared to single or dual energy technology. The presented work is part of the EUROSKY European project to develop a Single European Secure Air-Cargo Space. "Cargo" context implies the presence of relatively heavy objects and with potentially high atomic number. All the study is conducted on simulations with three different detectors: a typical dual energy sandwich detector, a realistic model of the commercial ME100 multi-energy detector marketed by MULTIX, and a ME100 "Cargo": a not yet existing modified multi-energy version of the ME100 more suited to air freight cargo inspection. Firstly, a comparison on simulated measurements shows the performances improvement of the new multi-energy detectors compared to the current dual-energy one. The relative performances are evaluated according to different criteria of separability or contrast-to-noise ratio and the impact of different parameters is studied (influence of channel number, type of materials and tube voltage). Secondly, performances of multi-energy detectors for overlaps processing in a dual-view system is accessed: the case of orthogonal projections has been studied, one giving dimensional values, the other one providing spectral data to assess effective atomic number. A method of overlap correction has been proposed and extended to multi-layer objects case. Therefore, Calibration and processing based on bi-material decomposition have been adapted for this purpose.

  10. Diffusion and bulk flow in phloem loading

    DEFF Research Database (Denmark)

    Dölger, Julia; Rademaker, Hanna; Liesche, Johannes


    diffusing back requires that the plasmodesmata connecting the bundle sheath with the intermediary cell act as extremely precise filters, which are able to distinguish between molecules that differ by less than 20% in size. In our modeling, we take into account the coupled water and sugar movement across......%-20% to the sucrose flux into the intermediary cells, while the main part is transported by diffusion. On the other hand, the subsequent sugar translocation into the sieve elements would very likely be carried predominantly by bulk water flow through the plasmodesmata. Thus, in contrast to apoplasmic loaders, all...... of molecular sizes. Comparing with the somewhat uncertain experimental values for sugar export rates, we expect the pores to be only 5%-10% larger than the hydraulic radius of the sucrose molecules. We find that the water flow through the plasmodesmata, which has not been quantified before, contributes only 10...

  11. Organoboron polymers for photovoltaic bulk heterojunctions. (United States)

    Cataldo, Sebastiano; Fabiano, Simone; Ferrante, Francesco; Previti, Francesco; Patanè, Salvatore; Pignataro, Bruno


    We report on the application of three-coordinate organoboron polymers, inherently strong electron acceptors, in flexible photovoltaic (PV) cells. Poly[(1,4-divinylenephenylene)(2,4,6-triisopropylphenylborane)] (PDB) has been blended with poly(3-hexylthiophene-2,5-diyl) (P3HT) to form a thin film bulk heterojunction (BHJ) on PET/ITO substrates. Morphology may be modulated to give a high percentage of domains (10-20 nm in size) allowing exciton separation. The photoelectric properties of the BHJs in devices with aluminium back electrodes were imaged by light beam induced current (LBIC) and light beam induced voltage (LBIV) techniques. Open circuit voltages, short circuit currents and overall external quantum efficiencies obtained are among the highest reported for all-polymer PV cells. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. A route to transparent bulk metals

    KAUST Repository

    Schwingenschlögl, Udo


    Hypothetical compounds based on a sapphire host are investigated with respect to their structural as well as electronic features. The results are obtained by electronic structure calculations within density functional theory and the generalized gradient approximation. A quarter of the Al atoms in Al 2O 3 is replaced by a 4d transition metal M ion, with d 0 to d 9 electronic configuration. We perform structure optimizations for all the compounds and analyze the electronic states. Due to the sizeable band gap of the Al 2O 3 host, we can identify promising candidates for transparent bulk metals. We explain the mechanisms leading to this combination of materials properties. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Holographic bulk viscosity: GPR vs EO

    CERN Document Server

    Buchel, Alex; Kiritsis, Elias


    Recently Eling and Oz (EO) proposed a formula for the holographic bulk viscosity, in arXiv:1103.1657, derived from the null horizon focusing equation. This formula seems different from that obtained earlier by Gubser, Pufu and Rocha (GPR) in arXiv:0806.0407 calculated from the IR limit of the two-point function of the trace of the stress tensor. The two were shown to agree only for some simple scaling cases. We point out that the two formulae agree in two non-trivial holographic theories describing RG flows. The first is the strongly coupled N=2* gauge theory plasma. The second is the semi-phenomenological model of Improved Holographic QCD.

  14. Tuneable film bulk acoustic wave resonators

    CERN Document Server

    Gevorgian, Spartak Sh; Vorobiev, Andrei K


    To handle many standards and ever increasing bandwidth requirements, large number of filters and switches are used in transceivers of modern wireless communications systems. It makes the cost, performance, form factor, and power consumption of these systems, including cellular phones, critical issues. At present, the fixed frequency filter banks based on Film Bulk Acoustic Resonators (FBAR) are regarded as one of the most promising technologies to address performance -form factor-cost issues. Even though the FBARs improve the overall performances the complexity of these systems remains high.  Attempts are being made to exclude some of the filters by bringing the digital signal processing (including channel selection) as close to the antennas as possible. However handling the increased interference levels is unrealistic for low-cost battery operated radios. Replacing fixed frequency filter banks by one tuneable filter is the most desired and widely considered scenario. As an example, development of the softwa...

  15. Interface control of bulk ferroelectric polarization

    Energy Technology Data Exchange (ETDEWEB)

    Yu, P [University of California, Berkeley; Luo, Weidong [ORNL; Yi, D. [University of California, Berkeley; Zhang, J.-X. [University of California, Berkeley; Rossell, M.D. [Lawrence Berkeley National Laboratory (LBNL); Yang, C.-H. [Korea Advanced Institute of Science and Technology; You, L. [University of California, Berkeley; Singh-Bhalla, G. B. [University of California, Berkeley & LBNL; Yang, S.Y [University of California, Berkeley; He, Q [University of California, Berkeley; Ramasse, Q. M. [Lawrence Berkeley National Laboratory (LBNL); Erni, R. [Lawrence Berkeley National Laboratory (LBNL); Martin, L. W. [University of Illinois, Urbana-Champaign; Chu, Y. H. [University of California, Berkeley; Pantelides, Sokrates T [ORNL; Pennycook, Stephen J [ORNL; Ramesh, R. [University of California, Berkeley


    The control of material interfaces at the atomic level has led to no- vel interfacial properties and functionalities. In particular, the study of polar discontinuities at interfaces between complex oxides lies at the frontier of modern condensed matter research. Here we em- ploy a combination of experimental measurements and theoretical calculations to demonstrate the control of a bulk property, namely ferroelectric polarization, of a heteroepitaxial bilayer by precise atomic-scale interface engineering. More specifically, the control is achieved by exploiting the interfacial valence mismatch to influence the electrostatic potential step across the interface, which manifests itself as the biased-voltage in ferroelectric hysteresis loops and determines the ferroelectric state. A broad study of diverse systems comprising different ferroelectrics and conducting perovskite un- derlayers extends the generality of this phenomenon.

  16. Criticality in Bulk Metallic Glass Constituent Elements (United States)

    Mota, Rodrigo Miguel Ojeda; Graedel, T. E.; Pekarskaya, Evgenia; Schroers, Jan


    Bulk metallic glasses (BMGs), which readily form amorphous phases during solidification, are increasingly being used in first applications of watch components, electronic casings, and sporting goods. The compositions of BMGs typically include four to six elements. Various political and geological factors have recently led to supply disruptions for several metals, including some present in BMG compositions. In this work, we assess the "criticality" of 22 technologically interesting BMG compositions, compare the results with those for three common engineering alloy groups, and derive recommendations for BMG composition choices from a criticality perspective. The criticality of BMGs is found to be generally much higher compared with those for the established engineering alloys. Therefore, criticality concerns should also be considered in the choice between existing and developing novel BMGs.

  17. Bulk disk resonator based ultrasensitive mass sensor

    DEFF Research Database (Denmark)

    Cagliani, Alberto; Davis, Zachary James


    In the framework of developing an innovative label-free sensor for multiarrayed biodetection applications, we present a novel bulk resonator based mass sensor. The sensor is a polysilicon disk which shows a Q-factor of 6400 in air at 68.8 MHz, resulting in mass resolutions down in the femtogram...... range. The sensor has been characterized in terms of sensitivity both for distributed mass detection, performing six consecutive depositions of e-beam evaporated Au, and localized mass detection, depositing approximately 7.5 pg of Pt/Ga/C three times consecutively with a Focused Ion Beam system....... The sensor has an extremely high distributed mass to frequency shift sensitivity of 60104 Hzcm2/¿g and shows a localized mass to frequency sensitivity up to 4405 Hz/pg with a localized mass resolution down to 15 fg. The device has been fabricated with a new microfabrication process that uses only two...

  18. How Many Bulk Metallic Glasses Are There? (United States)

    Li, Yanglin; Zhao, Shaofan; Liu, Yanhui; Gong, Pan; Schroers, Jan


    Quantitative prediction of glass forming ability using a priori known parameters is highly desired in metallic glass development; however proven to be challenging because of the complexity of glass formation. Here, we estimate the number of potential metallic glasses (MGs) and bulk metallic glasses (BMGs) forming systems and alloys, from empirically determined alloy design rules based on a priori known parameters. Specifically, we take into account atomic size ratio, heat of mixing, and liquidus temperature, which we quantify on binary glasses and centimeter-sized BMGs. When expanding into higher order systems that can be formed among 32 practical elements, we reduce the composition space for BMG formation using developed criteria by 106 times and estimate ∼3 million binary, ternary, quaternary, and quinary BMGs alloys.

  19. Rotary adsorbers for continuous bulk separations (United States)

    Baker, Frederick S [Oak Ridge, TN


    A rotary adsorber for continuous bulk separations is disclosed. The rotary adsorber includes an adsorption zone in fluid communication with an influent adsorption fluid stream, and a desorption zone in fluid communication with a desorption fluid stream. The fluid streams may be gas streams or liquid streams. The rotary adsorber includes one or more adsorption blocks including adsorbent structure(s). The adsorbent structure adsorbs the target species that is to be separated from the influent fluid stream. The apparatus includes a rotary wheel for moving each adsorption block through the adsorption zone and the desorption zone. A desorption circuit passes an electrical current through the adsorbent structure in the desorption zone to desorb the species from the adsorbent structure. The adsorbent structure may include porous activated carbon fibers aligned with their longitudinal axis essentially parallel to the flow direction of the desorption fluid stream. The adsorbent structure may be an inherently electrically-conductive honeycomb structure.

  20. Solid state properties from bulk to nano

    CERN Document Server

    Dresselhaus, Mildred; Cronin, Stephen; Gomes Souza Filho, Antonio


    This book fills a gap between many of the basic solid state physics and materials science books that are currently available. It is written for a mixed audience of electrical engineering and applied physics students who have some knowledge of elementary undergraduate quantum mechanics and statistical mechanics. This book, based on a successful course taught at MIT, is divided pedagogically into three parts: (I) Electronic Structure, (II) Transport Properties, and (III) Optical Properties. Each topic is explained in the context of bulk materials and then extended to low-dimensional materials where applicable. Problem sets review the content of each chapter to help students to understand the material described in each of the chapters more deeply and to prepare them to master the next chapters.

  1. Generation and Stability of Bulk Nanobubbles. (United States)

    Oh, Seung Hoon; Kim, Jong-Min


    Recently, extremely small bubbles, referred to as nanobubbles, have drawn increased attention due to their novel properties and great potential for various applications. In this study, a novel method for the generation of bulk nanobubbles (BNBs) was introduced, and stability of fabricated BNBs was investigated. BNBs were created from CO2 gas with a mixing method; the chemical identity and phase state of these bubbles can be determined via infrared spectroscopy. The presence of BNBs was observed with a nanoparticle tracking analysis (NTA). The ATR-FTIR spectra of BNBs indicate that the BNBs were filled with CO2 gas. Furthermore, the BNB concentration and its ζ-potential were about 2.94 × 108 particles/mL and -20 mV, respectively (24 h after BNB generation with a mixing time of 120 min). This indicates the continued existence and stability of BNBs in water for an extended period of time.

  2. Assessment of bioburden encapsulated in bulk materials (United States)

    Schubert, Wayne W.; Newlin, Laura; Chung, Shirley Y.; Ellyin, Raymond


    The National Aeronautics and Space Administration (NASA) imposes bioburden limitations on all spacecraft destined for solar system bodies that might harbor evidence of extant or extinct life. The subset of microorganisms trapped within solid materials during manufacture and assembly is referred to as encapsulated bioburden. In the absence of spacecraft-specific data, NASA relies on specification values to estimate total spacecraft encapsulated bioburden, typically 30 endospores/cm3 or 300 viable cells/cm3 in non-electronic materials. Specification values for endospores have been established conservatively, and represent no less than an order of magnitude greater abundance than that derived from empirical assessments of actual spacecraft materials. The goal of this study was to generate data germane to determining whether revised bulk encapsulated material values (lower than those estimated by historical specifications) tailored specifically to the materials designated in modern-day spacecraft design could be used, on a case-by-case basis, to comply with planetary protection requirements. Organic materials having distinctly different chemical properties and configurations were selected. This required more than one experimental and analytical approach. Filtration was employed for liquid electrolytes, lubricants were suspended in an aqueous solution and solids (wire and epoxy sealant) were cryogenically milled. The final data characteristic for all bioburden estimates was microbial colony formation in rich agar growth medium. To assess survival potential, three non-spore-forming bacterial cell lines were systematically encapsulated in an epoxy matrix, liberated via cryogenic grinding, and cultured. Results suggest that bulk solid materials harbor significantly fewer encapsulated microorganisms than are estimated by specification values. Lithium-ion battery electrolyte reagents housed fewer than 1 CFU/cm3. Results also demonstrated that non-spore-forming microorganisms

  3. Impact of a radio-frequency identification system and information interchange on clearance processes for cargo at border posts

    Directory of Open Access Journals (Sweden)

    Ernest Bhero


    Full Text Available Background: Improved operational efficiency is important to role players in cross-border logistics and trade corridors. Cargo owners and cargo forwarders have been particularly concerned about long delays in the processing and clearing of cargo at border posts. Field studies suggest that these delays are due to a combination of factors, such as a lack of optimum system configurations and non-optimised human-dependent operations, which make the operations prone to corruption and other malpractices.Objectives: This article presents possible strategies for improving some of the operations in this sector. The research hinges on two key questions: (1 what is the impact of information interchange between stakeholders on the cargo transit time and (2 how will cargo transit time be impacted upon by automatic identification of cargo and the status of cargo seals on arriving vehicles at the border?Method: The use of information communication systems enabled by automatic identification systems (incorporating radio-frequency identification technology is suggested.Results: Results obtained by the described simulation model indicate that improvements of up to 82% with regard to transit time are possible using these techniques.Conclusion: The findings therefore demonstrate how operations at border posts can be improved through the use of appropriate technology and configuration of the operations.

  4. Evaluation difference between mass of received cargo and mass of handed over the cargo in the determination of the masses by draft survey

    Directory of Open Access Journals (Sweden)

    Yakuta I. V.


    Full Text Available The paper provides the analysis of problems associated with the evaluation of difference between the mass of received and handed over cargo in determining the masses by draft survey and due to the difference in the measurement conditions at the loading and unloading ports (due to the change errors in various stages of the measurement procedures. The errors that may arise in determining the mass of the cargo due to roughness when measuring draft, due to using the inclinometer to determine the draft from one of boards, due to instrumental errors in the determination of the density of seawater, due to other possible errors have been investigated and evaluated. To estimate the errors of draft due to heaving and errors of inclinometer some formula are to be applied, their derivation has been done in this paper. It has been recommended to use the traditional formula of high-speed drawdown with the replacement of vessel speed on current rate to calculate the error of precipitation arising from the drawdowns ship on a current. The value per unit displacement draft from loading scale has been used to evaluate the error of the displacement appearing in the presence of draft errors. As a result two similar criteria (rigorous and statistical of allowable discrepancies calculated by draft survey mass of cargo in the port of loading and port of discharge have been substantiated. These criteria require the calculation and accumulation in a table of all the errors and calculate the total error of displacement. Criteria will allow the consignee and the carrier come to a reasonable and agreed decision about the significance of differences of the masses taking into account the indifference of conditions and measuring instruments.

  5. Radiopacity of bulk fill flowable resin composite materials. (United States)

    Yildirim, T; Ayar, M K; Akdag, M S; Yesilyurt, C


    The purpose of this study was to evaluate the radiopacity of currently marketed bulk fill flowable dental composite materials (Beautifil Bulk Flowable, SDR Flow, Filtek Bulk Fill Flow, and x-tra Base Bulk Fill). Six specimens of each material with a thickness of 1 mm were prepared, and digital radiographs were taken, using a CCD sensor along with an aluminum stepwedge and 1 mm-thick tooth slice. The mean gray level of each aluminum stepwedge and selected materials was measured, using the equal-density area tool of Kodak Dental Imaging software. The equivalent thickness of aluminum for each material was then calculated by using the stepwedge values in the CurveExpert version 1.4 program. The radiopacity of bulk fill flowable composites sorted in descending order as follows: Beautifil Bulk Flowable (2.96 mm Al) = x-tra base bulk fill (2.92 mm Al) = SureFil SDR Flow (2.89 mm Al) > Filtek Bulk Fill Flow (2.51 mm Al) (P materials had a radiopacity greater than dentin and enamel; their adequate radiopacity will help the clinicians during radiographic examination of restorations. Bulk fill composite materials have greater radiopacity, enabling clinicians to distinguish the bulk fill composites from dentin and enamel.

  6. Locality, bulk equations of motion and the conformal bootstrap

    Energy Technology Data Exchange (ETDEWEB)

    Kabat, Daniel [Department of Physics and Astronomy, Lehman College, City University of New York,250 Bedford Park Blvd. W, Bronx NY 10468 (United States); Lifschytz, Gilad [Department of Mathematics, Faculty of Natural Science, University of Haifa,199 Aba Khoushy Ave., Haifa 31905 (Israel)


    We develop an approach to construct local bulk operators in a CFT to order 1/N{sup 2}. Since 4-point functions are not fixed by conformal invariance we use the OPE to categorize possible forms for a bulk operator. Using previous results on 3-point functions we construct a local bulk operator in each OPE channel. We then impose the condition that the bulk operators constructed in different channels agree, and hence give rise to a well-defined bulk operator. We refer to this condition as the “bulk bootstrap.” We argue and explicitly show in some examples that the bulk bootstrap leads to some of the same results as the regular conformal bootstrap. In fact the bulk bootstrap provides an easier way to determine some CFT data, since it does not require knowing the form of the conformal blocks. This analysis clarifies previous results on the relation between bulk locality and the bootstrap for theories with a 1/N expansion, and it identifies a simple and direct way in which OPE coefficients and anomalous dimensions determine the bulk equations of motion to order 1/N{sup 2}.

  7. Detection of Special Nuclear Material in Cargo Containers Using Neutron Interrogation

    Energy Technology Data Exchange (ETDEWEB)

    Slaughter, D; Accatino, M; Bernstein, A; Candy, J; Dougan, A; Hall, J; Loshak, A; Manatt, D; Meyer, A; Pohl, B; Prussin, S; Walling, R; Weirup, D


    The goal of the work reported here is to develop a concept for an active neutron interrogation system that can detect small targets of SNM contraband in cargo containers, roughly 5 kg HEU or 1 kg Pu, even when well shielded by a thick cargo. It is essential that the concept be reliable and have low false-positive and false-negative error rates. It also must be rapid to avoid interruption of commerce, completing the analysis in minutes. A new radiation signature unique to SNM has been identified that utilizes high-energy (E{sub {gamma}} = 3-7 MeV) fission product {gamma}-ray emission. Fortunately, this high-energy {gamma}-ray signature is robust in that it is very distinct compared to normal background radiation where there is no comparable high-energy {gamma}-ray radiation. Equally important, it has a factor of 10 higher yield than delayed neutrons that are the basis of classical interrogation technique normally used on small unshielded specimens of SNM. And it readily penetrates two meters of low-Z and high-Z cargo at the expected density of {approx} 0.5 gm/cm{sup 3}. Consequently, we expect that in most cases the signature flux at the container wall is at least 2-3 decades more intense than delayed neutron signals used historically and facilitates the detection of SNM even when shielded by thick cargo. Experiments have verified this signature and its predicted characteristics. However, they revealed an important interference due to the activation of {sup 16}O by the {sup 16}O(n,p){sup 16}N reaction that produces a 6 MeV {gamma}-ray following a 7-sec {beta}-decay of the {sup 16}N. This interference is important when irradiating with 14 MeV neutrons but is eliminated when lower energy neutron sources are utilized since the reaction threshold for {sup 16}O(n,p){sup 16}N is 10 MeV. The signature {gamma}-ray fluxes exiting a thick cargo can be detected in large arrays of scintillation detectors to produce useful signal count rates of 2-4 x 10{sup 4} cps. That is high

  8. Bulk Modulus Relaxation in Partially Molten Dunite? (United States)

    Jackson, I.; Cline, C. J., II


    Synthetic solgel-derived Fo90 olivine was mixed with 3.5 wt % basaltic glass and hot-pressed within Ni/Fe foil to produce a dense aggregate expected to contain a small melt fraction at temperatures ≥ 1100°C. This specimen was precision ground and tested in both torsional and flexural forced oscillation to determine the relaxation behavior of both shear (G) and bulk (K) moduli at seismic frequencies. A recent upgrade of our experimental facility allows such measurements to be made without alteration of the driver/detector geometry, and uses an oscillating bending force rather than a bending moment, as previously described. The torsional and flexural tests were conducted in a gas apparatus at 200 MPa confining pressure, with oscillation periods ranging between 1 and 1000 s, during slow staged-cooling from 1300 to 25°C. Shear modulus and associated dissipation data are consistent with those for melt-bearing olivine specimens previously tested in torsion, with a pronounced dissipation peak superimposed on high-temperature background within the 1-1000 s observational window at temperatures of 1100-1200°C. A filament elongation model relates the observed flexural measurements to the variations along the experimental assembly of the complex Young's modulus (E*), bending moment and diametral moment of inertia. With E* given by 1/E*=1/(3G*) + 1/(9K*), and the complex shear modulus (G*) derived from torsional oscillation, any relaxation of K can be identified. Preliminary modeling shows that the viscoelastic properties in flexure are broadly consistent with those expected from the shear-mode viscoelasticity with anharmonic (real) values of K. However, some discrepancies between modeled results and flexure data at super-solidus temperatures require further investigation of possible differences in shear modulus relaxation between the torsional and flexural modes, and of potential relaxation of the bulk modulus through stress-induced changes in melt redistribution and

  9. Bulk density and relationship air/water of horticultural substrate


    Fernandes,Carolina; Corá, José Eduardo


    Change on substrate bulk density during the growing period may negatively affect other substrate physical properties and, consequently, plant growth. The objectives of this research were 1) to characterize physical properties of two horticultural substrates (S1 and S2), 2) to evaluate the effect of different bulk densities values of those substrates on their air/water relationship, and 3) to develop mathematical functions to estimate the air/water relationship by increasing substrates bulk de...

  10. Isolation and characterization of culturable bacteria from bulk soil ...

    African Journals Online (AJOL)

    Olaf _SK


    Mar 18, 2015 ... pods with large brownish-black oil and protein-rich seeds. (Holse et al., 2010). ... nutrition and increase food availability in arid ecological zones. .... 3. Bulk. Eight. BP6, BP7, BP8, BP9, BP10, BP11, BP12, BP13. 4. Bulk. Three. BP14, BP15, BP16. 5. Bulk. Three. BP17, BP18, BP19. 6. Rhizosphere. Two.

  11. Determination of Bulk Dimensional Variation in Castings

    Energy Technology Data Exchange (ETDEWEB)

    Dr. James F. Cuttino Dr. Edward P. Morse


    The purpose of this work is to improve the efficiency of green sand foundries so that they may continue to compete as the most cost-effective method of fabrication while meeting tightening constraints on near-net shape manufacturing. In order to achieve this objective, the study is divided into two major components. The first component concentrated on identifying which processes control surface finish on the castings and which provide potential reductions in variations. The second component identified metrological methods that effectively discern between the geometry of bulk material versus surface finish in order to more accurately determine the quality of a part. The research resulted in the determination of an empirical relationship relating pouring parameters to dimensional variation, with an R2 value of greater than 0.79. A significant difference in variations obtained from vertical vs. horizontal molding machines was also noticed. When analyzed separately, however, the resulting empirical relationships for horizontal and vertical machines had reduced R2 values, probably due to the reduced data sets. Significant parameters when considering vertical and horizontal molding machines together included surface roughness, pattern type, iron type, pouring rate, copper content, amount of Western Bentonite, and permeability.

  12. FAA bulk technology overview for explosives detection (United States)

    Novakoff, Alan K.


    The Federal Aviation Administration (FAA) is the leading federal agency responsible for encouraging and fostering the development of a safe, secure, and efficient national airspace system (NAS). Our goal is to establish an operating environment that ensures a threat-free system to preclude acts of terrorism and fatalities. As part of the process to meet this goal, our research and development activities continually search for technologies to ensure aviation security. Recent acts of terrorism against the aviation community have demonstrated an increasing level of sophistication in the design and deployment of explosive devices. In order to prevent the introduction of explosives onto an aircraft they must be detected prior to passenger and baggage loading. The Bulk Detection program is one method of developing a number of technologies that 'see' into and 'alarm' on suspect baggage. These detection devices must be capable of providing this serve with a confidence commensurate with the state-of-the- art available today. This program utilizes the expertise of government agencies, universities and industries working toward constructing their plans and executing their designs to produce the best available equipment.

  13. Recent developments of film bulk acoustic resonators (United States)

    Gao, Junning; Liu, Guorong; Li, Jie; Li, Guoqiang


    Film bulk acoustic wave resonator (FBAR) experienced skyrocketing development in the past 15 years, owing to the explosive development of mobile communication. It stands out in acoustic filters mainly because of high quality factor, which enables low insertion loss and sharp roll off. Except for the massive application in wireless communication, FBARs are also promising sensors because of the high sensitivity and readily integration ability to miniaturize circuits. On the ground of summarizing FBAR’s application in wireless communication as filters and in sensors including electronic nose, bio field, and pressure sensing, this paper review the main challenges of each application faced. The number of filters installed in the mobile phone has being grown explosively, which leads to overcrowded bands and put harsh requirements on component size and power consumption control for each unit. Data flow and rate are becoming increasingly demanding as well. This paper discusses three promising technical strategies addressing these issues. Among which coupled resonator filter is given intense attention because it is able to vigorously reduce the filter size by stacking two or more resonators together, and it is a great technique to increase data flow and rate. Temperature compensation methods are discussed considering their vital influence on frequency stability. Finally, materials improvement and novel materials exploration for band width modulation, tunable band acquisition, and quality factor improvement are discussed. The authors appeal attention of the academic society to bring AlN epitaxial thin film into the FBAR fabrication and have proposed a configuration to implement this idea.

  14. Tip-enhanced bulk photovoltaic effect (United States)

    Sturman, B.; Podivilov, E.


    Using the conventional macroscopic description of the bulk photovoltaic effect we analyze the light-induced currents and electric fields arising in the optical configuration with a continuous bottom electrode and a small circular top electrode. This scheme is relevant to recent experiments on the tip-enhanced photovoltaic effect in ferroelectrics. It is shown that a light-induced electric field remains nonzero inside the sample even in the short-circuit regime. Moreover, it is enhanced compared to the photovoltaic field in a large area and strongly enhanced near the top electrode. A field-assisted collection of charge carriers from the illuminated area produces a strong local enhancement of the current density near the top electrode. The tip-enhanced electric field is typically parallel to the photovoltaic current. It is sufficient to repolarize the crystal near the top electrode. The effect of the tip enhancement on the light-current transformation efficiency is considered, and predictions for the tip radius and sample thickness dependencies of the total light-induced current are made.

  15. Photoelectron spectroscopy bulk and surface electronic structures

    CERN Document Server

    Suga, Shigemasa


    Photoelectron spectroscopy is now becoming more and more required to investigate electronic structures of various solid materials in the bulk, on surfaces as well as at buried interfaces. The energy resolution was much improved in the last decade down to 1 meV in the low photon energy region. Now this technique is available from a few eV up to 10 keV by use of lasers, electron cyclotron resonance lamps in addition to synchrotron radiation and X-ray tubes. High resolution angle resolved photoelectron spectroscopy (ARPES) is now widely applied to band mapping of materials. It attracts a wide attention from both fundamental science and material engineering. Studies of the dynamics of excited states are feasible by time of flight spectroscopy with fully utilizing the pulse structures of synchrotron radiation as well as lasers including the free electron lasers (FEL). Spin resolved studies also made dramatic progress by using higher efficiency spin detectors and two dimensional spin detectors. Polarization depend...

  16. Dilepton radiation and bulk viscosity in heavy-ion collisions (United States)

    Vujanovic, Gojko; Paquet, Jean-François; Shen, Chun; Denicol, Gabriel S.; Jeon, Sangyong; Gale, Charles; Heinz, Ulrich


    Starting from IP-Glasma initial conditions, we investigate the effects of bulk pressure on thermal dilepton production at the Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC) energies. Though results of the thermal dilepton v2 under the influence of both bulk and shear viscosity is presented for top RHIC energy, more emphasis is put on LHC energy where such a calculation is computed for the first time. The effects of the bulk pressure on thermal dilepton v2 at the LHC are explored through bulk-induced modifications on the dilepton yield.

  17. A propagating ATPase gradient drives transport of surface-confined cellular cargo (United States)

    Vecchiarelli, Anthony; Neuman, Keir; Mizuuchi, Kiyoshi


    The process of DNA segregation is of central importance for all organisms. Although eukaryotic mitosis is relatively well established, the most common mechanism employed for bacterial DNA segregation has been unclear. ParA ATPases form dynamic patterns on the bacterial nucleoid, to spatially organize plasmids, chromosomes and other large cellular cargo, but the force generating mechanism has been a source of controversy and debate. A dominant view proposes that ParA-mediated transport and cargo positioning occurs via a filament-based mechanism that resembles eukaryotic mitosis. Here we present direct evidence against such models. Our cell-free reconstitution supports a non-filament-based mode of transport that may be as widely found in nature as actin filaments and microtubules.

  18. Finite element analysis of container ship's cargo hold using ANSYS and POSEIDON software (United States)

    Tanny, Tania Tamiz; Akter, Naznin; Amin, Osman Md.


    Nowadays ship structural analysis has become an integral part of the preliminary ship design providing further support for the development and detail design of ship structures. Structural analyses of container ship's cargo holds are carried out for the balancing of their safety and capacity, as those ships are exposed to the high risk of structural damage during voyage. Two different design methodologies have been considered for the structural analysis of a container ship's cargo hold. One is rule-based methodology and the other is a more conventional software based analyses. The rule based analysis is done by DNV-GL's software POSEIDON and the conventional package based analysis is done by ANSYS structural module. Both methods have been applied to analyze some of the mechanical properties of the model such as total deformation, stress-strain distribution, Von Mises stress, Fatigue etc., following different design bases and approaches, to indicate some guidance's for further improvements in ship structural design.

  19. Maritime Archaeology and Trans-Oceanic Trade: A Case Study of the Oranjemund Shipwreck Cargo, Namibia (United States)

    Chirikure, Shadreck; Sinamai, Ashton; Goagoses, Esther; Mubusisi, Marina; Ndoro, W.


    Routine sand dredging for alluvial diamonds at Oranjemund on the southern coast of Namibia exposed remnants of a long forgotten Portuguese merchant ship believed to have wrecked in the 1530s. The rescue excavations yielded over 40 tons of cargo consisting of thousands of gold and silver coins, tons of copper and lead ingots, and large quantities of ivory together with food refuse, part of personal possessions and the superstructure of the ship. This paper discusses the cargo from the shipwreck. The varying provenances show that overland inter-and intra-regional networks fed into the maritime trade between Europe and the Indian sub-continent. As such, the wreck is a lens through which we can view what was happening on the seas as well as on land. Finally we consider wider issues raised by this discovery relating to the protection and management of such material wherever it may be found in future.

  20. Art concepts of EVA retrieval of WESTAR/PALAPA satellites to Cargo bay (United States)


    Art concepts of EVA retrieval of WESTAR/PALAPA satellites to Cargo bay docking. Views include: astronuat approaching satellite using the manned manuevering unit (MMU) while the shuttle hovers above the earth (35276); Satellite sitting in open cargo bay (35277); Astronaut manipulating satellite in preparation for placing it in orbit. The satellite is in the grasp of the extended remote manipulator system's (RMS) end effector (35278); Astronaut using MMU to approach satellite in orbit while shuttle with open payload bay remains below (35279); Astronauts standing in foot restraints in the open payload bay. The satellite is suspended above them by the RMS and they appear to be repairing it (35280); Front view of shuttle in orbit with RMS extended placing satellite in orbit (35281); One astronaut stands in foot restraints in the payload bay under the satellite he is repairing. The other astronaut uses the MMU to work from above. The satellite is suspended by the RMS (35282).

  1. On the possibility of the in-cell molecular motors working as cargo moorings only

    CERN Document Server

    Lisowski, Bartosz


    Although active transport is considered the most efficient way of depositing materials in the appropriate compartments within living cells, free diffusion remains the energetically cheapest and most widespread determinant of the in-cell dynamics. Here we investigate the hypothesis of cargoes - vesicles or organelles - being transported by the means of free diffusion, limited spatially by the molecular motors. Routinely navigating through ever-changing and unsteady environment, utilizing chemical energy (e.g. from hydrolyzing ATP), as the result they transport cell's crucial components, such as neurotransmitters and organelles. In our model the motor, which we identify with kinesin-1 walking along the microtubule, tethers the cargo in the same manner as a mooring rope attached to a bollard holds a ship from drifting toward the open sea. We study the model behavior in the context of optical trap single molecule experiments, mimicking their procedures in our simulations and investigate how the mechanical propert...

  2. Model of Optimal Cargo Transport Structure by Full Container Ship on Predefined Sailing Route

    Directory of Open Access Journals (Sweden)

    Serđo Kos


    Full Text Available This paper presents the mathematical model for solving theproblem of defining optimal cargo transport structure, occurringwhen, on a predefined sailing route, adequate number ofcontainers of various types, masses and sizes, possibly includingRO!RO cargo, is to be selected, i.e., a "container lot" is to beestablished in loading ports with the aim of gaining maximumship profit and, at the same time, of exploiting useful load andtransport capacity of container ship as much as possible. Theimplementation of the proposed model enables considerableincrease in the efficiency of container ship operations. Themodel was tested using a numerical example with real data.The applied post-optimal analysis examines the influence ofchange in some values of the mathematical model on the resultingoptimal program.

  3. Microbial behaviour and cross contamination between cargoes in containerized transportation of food

    DEFF Research Database (Denmark)

    Abban, Stephen

    , either with refrigerated units or otherwise. Foodborne pathogenic disease outbreaks have caused havoc including loss of lives, permanent morbidity, ailments with high costs of treatment and even collapse of businesses in various parts of the wold. With transportation needed in so many stages of the food...... involved in foodborne disease outbreaks and their use in the present study have been discussed. Both Gram negative and Gram positive bacteria have been used in various experiments. The history of containerized transportation and its revolutionary role in the world of commerce is also briefly traced......Transportation is central to the global food and feed supply chain. Thus issues of safety, especially cross contamination with pathogens during food transit should be important in food handling operations. A large proportion of the worlds’ food cargo is moved using intermodal cargo containers...

  4. [Biomonitoring of ochratoxin A in a small sample of cargo workers handling grains and raw coffee]. (United States)

    Degen, G H; Meifort, J; Blaszkewicz, M


    Handling cargo such as grains and raw coffee beans may result in an inhalation mycotoxin-containing dusts from these commodities. Ochratoxin A (OTA) was analyzed in blood samples obtained from nine cargo workers who handle these commodities at the Hamburg harbour. The OTA plasma levels ranged between 0.14 and 1.04 ng/ml. The mean (0.5±0.3) and median value (0.42 ng/ml) for this sample are slightly higher than those reported previously for the general population in Germany resulting from dietary OTA exposure alone. Our preliminary data point to a possible inhalation exposure, but further investigations are necessary for a definite proof of this exposure. This pilot study is an example of the usefulness of biomonitoring for OTA in occupational contexts.

  5. C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells


    Charest-Morin, Xavier; P?pin, R?my; Gagn?-Henley, Ang?lique; Morissette, Guillaume; Lodge, Robert; Marceau, Fran?ois


    The C–C chemokine receptor-7 (CCR7) is a G protein coupled receptor that has a role in leukocyte homing, but that is also expressed in aggressive tumor cells. Preclinical research supports that CCR7 is a valid target in oncology. In view of the increasing availability of therapeutic monoclonal antibodies that carry cytotoxic cargoes, we studied the feasibility of forcing intact cells to internalize known monoclonal antibodies by exploiting the cycle of endocytosis and recycling triggered by t...

  6. Replacement design study for lighter amphibious re-supply cargo 5 Ton, amphibious vehicle LARC V


    Kaczmarek, Ryszard B.


    This thesis document was issued under the authority of another institution, not NPS. At the time it was written, a copy was added to the NPS Library Collection for reasons not now known. It has been included in the digital archive for its historical value to NPS. Not believed to be a CIVINS (Civilian Institutions) title. This project examines LARC V, which is water and land interface vehicle designed for support of amphibious operations (troops and cargo transport) in rivers and protect...

  7. Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes. (United States)

    Purushothaman, Anurag; Bandari, Shyam K; Chandrashekar, Darshan S; Jones, Richard J; Lee, Hans C; Weber, Donna M; Orlowski, Robert Z


    Tumor cells produce and utilize exosomes to promote tumor growth and metastasis. Tumor-cell-derived exosomes deliver cargos that partially mimic the contents of the parent cell to nearby or distant normal or abnormal cells, thereby reprogramming the recipient cells to support tumor progression. Mechanisms by which tumor-derived exosomes subserve the tumor are under intense investigation. Here we demonstrate a critical role of the chondroitin sulfate proteoglycan serglycin in regulating the protein cargo and functions of myeloma cell-derived exosomes. Previous studies have shown that serglycin, the only known intracellular proteoglycan, functions mainly in the storage of basically charged components within the intracellular granules/vesicles via serglycin's densely clustered, negatively charged glycosaminoglycan chains. Here we demonstrate that serglycin plays a critical role in the protein cargo loading of tumor-derived exosomes. Serglycin was detected in exosomes derived from cell culture supernatants of human myeloma cell lines and serum of myeloma patients. Mass spectrometry analysis of exosomal proteins identified significantly fewer protein components within exosomes derived from serglycin-knockdown myeloma cells than within exosomes from control cells. On gene ontology analysis, exosomes derived from serglycin-knockdown cells, but not from control cells, lacked many proteins that are required for mediating different cellular processes. In functional assays, exosomes from serglycin-knockdown cells failed to induce an invasive phenotype in myeloma cells and failed to promote migration of macrophages. These findings reveal that serglycin plays an important role in maintaining the protein cargo in tumor-derived exosomes and suggest that targeting serglycin may temper the influence of these exosomes on cancer progression.

  8. Intramolecular transport of small-molecule cargo in a nanoscale device operated by light. (United States)

    Chen, Jiawen; Wezenberg, Sander J; Feringa, Ben L


    An intramolecular cargo transport device, based on a light-driven molecular motor, is presented. Detailed UV-vis and (1)H NMR studies demonstrate that the gripper attached to the upper half of the molecular motor is able to pick up an acetyl group from one side of the lower stator and, after a photochemical Z-E isomerization, drop it on the opposite side.

  9. Evaluation of The Operational Benefits Versus Costs of An Automated Cargo Mover (United States)


    logistics footprint and life-cycle cost are presented as part of this report. Analysis of modeling and simulation results identified statistically...investigation of other potential benefits or drawbacks. 14. SUBJECT TERMS autonomous cargo mover, cost analysis , operational logistics , life-cycle...and from USMC aircraft. Also, this report provides critical information such as projected cost estimates and logistics analysis (e.g., spare parts


    Directory of Open Access Journals (Sweden)



    Full Text Available The problem of real time cargo-flows management in the integrated production and transportation system on example of machine-building enterprise is viewed optimal number of order cards in production and transportation system, which provides reduction in logistic costs. The building approach of membership function of linguistic terms, which characterize work-in-process level and waiting time, based on deterministic stock management model and queuing system is proposed.

  11. State of the Art and Development Trends of the Digital Radiography Systems for Cargo Inspection


    Udod, Viktor Anatolievich; J, .; Osipov, Sergey Pavlovich; Chakhlov, Sergey Vladimirovich; Temnik, Anatoly Konstantinovich


    Increasing requirements for technical parameters of inspection digital radiography systems are caused by increasing incidences of terrorism, drug trafficking and explosives via variety of transport. These requirements have determined research for new technical solutions that enable to ensure the safety of passengers and cargos in real-time. The main efforts in the analyzed method of testing are aimed at the creation of new and modernization of operated now systems of digital radiography as a ...

  12. Myosin V attachment to cargo requires the tight association of two functional subdomains


    Pashkova, Natasha; Catlett, Natalie L.; Novak, Jennifer L.; Wu, Guanming; Lu, Renne; Cohen, Robert E.; Weisman, Lois S.


    The myosin V carboxyl-terminal globular tail domain is essential for the attachment of myosin V to all known cargoes. Previously, the globular tail was viewed as a single, functional entity. Here, we show that the globular tail of the yeast myosin Va homologue, Myo2p, contains two structural subdomains that have distinct functions, namely, vacuole-specific and secretory vesicle–specific movement. Biochemical and genetic analyses demonstrate that subdomain I tightly associates with subdomain I...

  13. Multi-Criteria Optimisation of Liquid Cargo Transport According to Linguistic Approach to the Route Selection Task

    Directory of Open Access Journals (Sweden)

    Guze Sambor


    Full Text Available The main aim of the paper is to present the possibility of use of the multi-criteria optimization method Analytical Hierarchy Process (AHP to liquid cargo transportation by sea. Finding the optimal solution is not simple. There are many factors influencing the shipping process. In the case of liquid cargo, the most important thing is the safety of the crew, ship, and environment. Therefore, the Mathematical Theory of Evidence is introduced and used to determine the optimal path in terms of time and safety of transport. Moreover, the details of liquid cargo transport process are described with particular attention to ship to ship operations. Besides, the basic concept of the AHP method, steps of the algorithm are introduced. Finally, the multicriteria optimization of the transport of the liquid cargo from the Persian Gulf to Port of Gdansk is done. It is based on the experts′ opinions.

  14. 76 FR 28315 - Security Zone; Vessels Carrying Hazardous Cargo, Sector Columbia River Captain of the Port Zone (United States)


    ... cargoes include, but are not limited to, liquefied petroleum gas, ammonium nitrate and associated mixtures... Department of Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide...


    Directory of Open Access Journals (Sweden)

    Ariel Soltura Laseria


    Full Text Available En el trabajo se presenta una tecnología para la determinación de los perfiles de cargo por competencias en las organizaciones cubanas con base científica, fundamentada en la creciente necesidad de dirigir los esfuerzos individuales hacia el cumplimiento de la estrategia. La tecnología provee a las organizaciones de una forma de determinar la estructura de competencias que ha de adoptar para satisfacer las demandas o necesidades de clientes o usuarios, estado, proveedores y sociedad, en función de su cultura, procesos, estructura, rivalidad de competidores -en caso que exista y la estrategia como guía del proceso, donde los perfiles de cargo por competencias desempeñan el papel fundamental para la implantación de la estrategia. Palabras Clave Gestión de (por competencias, perfiles de competencias, diseño estratégico de perfiles de cargo por competencias.

  16. Research on characteristics of radiated noise of large cargo ship in shallow water (United States)

    Liu, Yongdong; Zhang, Liang


    With the rapid development of the shipping industry, the number of the world's ship is gradually increasing. The characteristics of the radiated noise of the ship are also of concern. Since the noise source characteristics of multichannel interference, the surface wave and the sea temperature microstructure and other reasons, the sound signal received in the time-frequency domain has varying characteristics. The signal of the radiated noise of the large cargo ship JOCHOH from horizontal hydrophone array in some shallow water of China is processed and analyzed in the summer of 2015, and the results show that a large cargo ship JOCHOH has a number of noise sources in the direction of the ship's bow and stern lines, such as host, auxiliary and propellers. The radiating sound waves generated by these sources do not meet the spherical wave law at lower frequency in the ocean, and its radiated noise has inherent spatial distribution, the variation characteristics of the radiated noise the large cargo ship in time and frequency domain are given. The research method and results are of particular importance.

  17. Poly- Versus Mono-Energetic Dual-Spectrum Non-Intrusive Inspection of Cargo Containers (United States)

    Martz, Harry E.; Glenn, Steven M.; Smith, Jerel A.; Divin, Charles J.; Azevedo, Stephen G.


    In this paper, based on an invited talk at SORMA (May 2016), we present an overview of x-ray sources, detectors and system configurations for non-intrusive inspection (NII) of cargo containers. Our emphasis is on dual-energy x-ray NII for detecting high-atomic-number (Z ≥ 72) materials such as tungsten shielding and special nuclear materials (SNM). Standard single-energy (MeV and above) x-rays needed to penetrate and image cargo provide little SNM contrast, whereas dual-energy x-ray NII is demonstrated as a way to improve the selectivity of materials with Zx-ray source technologies - polyenergetic dual-energy (PDE) and quasi-monoenergetic x-ray sources (QMXS) - we investigate their trade-offs and future prospects using experimental and simulated results. The reduced scatter and larger separation of low- and high-energy photons provided by QMXS offers improved high-Z material contrast, but practical considerations such as flux and pulse rate need to be solved before making a deployable system. Straight-ray simulations show factor of four increases in contrast for QMXS over PDE scans of tin (Z=50) and iron (Z=26) relative to a uranium plate (Z=92) behind 20 cm of iron simulated cargo.

  18. Structural Design and Analysis of Un-pressurized Cargo Delivery Vehicle (United States)

    Martinovic, Zoran N.


    As part of the Exploration Systems Architecture Study, NASA has defined a family of vehicles to support lunar exploration and International Space Station (ISS) re-supply missions after the Shuttle s retirement. The Un-pressurized Cargo Delivery Vehicle (UCDV) has been envisioned to be an expendable logistics delivery vehicle that would be used to deliver external cargo to the ISS. It would be launched on the Crew Launch Vehicle and would replace the Crew Exploration Vehicle. The estimated cargo would be the weight of external logistics to the ISS. Determining the minimum weight design of the UCDV during conceptual design is the major issue addressed in this paper. This task was accomplished using a procedure for rapid weight estimation that was based on Finite Element Analysis and sizing of the vehicle by the use of commercially available codes. Three design concepts were analyzed and their respective weights were compared. The analytical structural weight was increased by a factor to account for structural elements that were not modeled. Significant reduction in weight of a composite design over metallic was achieved for similar panel concepts.

  19. Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. (United States)

    Hosoya, Hitomi; Dobroff, Andrey S; Driessen, Wouter H P; Cristini, Vittorio; Brinker, Lina M; Staquicini, Fernanda I; Cardó-Vila, Marina; D'Angelo, Sara; Ferrara, Fortunato; Proneth, Bettina; Lin, Yu-Shen; Dunphy, Darren R; Dogra, Prashant; Melancon, Marites P; Stafford, R Jason; Miyazono, Kohei; Gelovani, Juri G; Kataoka, Kazunori; Brinker, C Jeffrey; Sidman, Richard L; Arap, Wadih; Pasqualini, Renata


    A major challenge of targeted molecular imaging and drug delivery in cancer is establishing a functional combination of ligand-directed cargo with a triggered release system. Here we develop a hydrogel-based nanotechnology platform that integrates tumor targeting, photon-to-heat conversion, and triggered drug delivery within a single nanostructure to enable multimodal imaging and controlled release of therapeutic cargo. In proof-of-concept experiments, we show a broad range of ligand peptide-based applications with phage particles, heat-sensitive liposomes, or mesoporous silica nanoparticles that self-assemble into a hydrogel for tumor-targeted drug delivery. Because nanoparticles pack densely within the nanocarrier, their surface plasmon resonance shifts to near-infrared, thereby enabling a laser-mediated photothermal mechanism of cargo release. We demonstrate both noninvasive imaging and targeted drug delivery in preclinical mouse models of breast and prostate cancer. Finally, we applied mathematical modeling to predict and confirm tumor targeting and drug delivery. These results are meaningful steps toward the design and initial translation of an enabling nanotechnology platform with potential for broad clinical applications.

  20. MW-Class Electric Propulsion System Designs for Mars Cargo Transport (United States)

    Gilland, James H.; LaPointe, Michael R.; Oleson, Steven; Mercer, Carolyn; Pencil, Eric; Maosn, Lee


    Multi-kilowatt electric propulsion systems are well developed and have been used on commercial and military satellites in Earth orbit for several years. Ion and Hall thrusters have also propelled robotic spacecraft to encounters with asteroids, the Moon, and minor planetary bodies within the solar system. High power electric propulsion systems are currently being considered to support piloted missions to near earth asteroids, as cargo transport for sustained lunar or Mars exploration, and for very high-power piloted missions to Mars and the outer planets. Using NASA Mars Design Architecture 5.0 as a reference, a preliminary parametric analysis was performed to determine the suitability of a nuclear powered, MW-class electric propulsion system for Mars cargo transport. For this initial analysis, high power 100-kW Hall thrusters and 250-kW VASIMR engines were separately evaluated to determine optimum vehicle architecture and estimated performance. The DRA 5.0 cargo mission closed for both propulsion options, delivering a 100 t payload to Mars orbit and reducing the number of heavy lift launch vehicles from five in the baseline DRA 5.0 architecture to two using electric propulsion. Under an imposed single engine-out mission success criteria, the VASIMR system took longer to reach Mars than did the Hall system, arising from the need to operate the VASIMR thrusters in pairs during the spiral out from low Earth orbit.

  1. Probing the structure and in silico stability of cargo loaded DNA icosahedra using MD simulations. (United States)

    Joshi, Himanshu; Bhatia, Dhiraj; Krishnan, Yamuna; Maiti, Prabal K


    Platonic solids such as polyhedra based on DNA have been deployed for multifarious applications such as RNAi delivery, biological targeting and bioimaging. All of these applications hinge on the capability of DNA polyhedra for molecular display with high spatial precision. Therefore high resolution structural models of such polyhedra are critical to widen their applications in both materials and biology. Here, we present an atomistic model of a well-characterized DNA icosahedron, with demonstrated versatile functionalities in biological systems. We study the structure and dynamics of this DNA icosahedron using fully atomistic molecular dynamics (MD) simulation in explicit water and ions. The major modes of internal motion have been identified using principal component analysis. We provide a quantitative estimate of the radius of gyration (R g ), solvent accessible surface area (SASA) and volume of the icosahedron which is essential to estimate its maximal cargo carrying capacity. Importantly, our simulation of gold nanoparticles (AuNPs) encapsulated within DNA icosahedra revealed enhanced stability of the AuNP loaded DNA icosahedra compared to empty icosahedra. This is consistent with the experimental results that show high yields of cargo-encapsulated DNA icosahedra that have led to its diverse applications for precision targeting. These studies reveal that the stabilizing interactions between the cargo and the DNA scaffold powerfully position DNA polyhedra as targetable nanocapsules for payload delivery. These insights can be exploited for precise molecular display for diverse biological applications.

  2. Efficiency Analysis of Additions of Ice Flake in Cargo Hold Cooling System of Fishing Vessel

    Directory of Open Access Journals (Sweden)

    Amiadji Amiadji


    Full Text Available As a maritime nation, the majority of people's livelihood in Indonesia coast is as a fishermen. The process of preserving fish after being caught will determine how good the product quality. One of process on preserving fish that can be done is to perform the cooling process using a cooling machine on board. Refrigeration system certainly requires high electrical power consumption. That high power usage can be reduced as much as possible, one of which is to add chopped ice (ice flake on a fishing boat cargo space. So that the load for cooling can be reduced.The purpose of this thesis is to find out how the influence of the addition of ice flake on cooling load in the cargo hold of fishing vessels, and to know how much power is used when the cooling machine is combined with the addition of ice flake. In this analysis cooling load calculation refers to the standard ISO 7547.from the results of analysis found that the addition of ice flake on cargo space can reduce cooling load and can reduce electricity consumption day in the main vessel for the addition comparison flake ice and fish weight of 1: 1.

  3. Amphiphilic nanocapsules entangled with organometallic coordination polymers for controlled cargo release. (United States)

    Liang, Guodong; Ni, Huan; Bao, Suping; Zhu, Fangming; Gao, Haiyang; Wu, Qing; Tang, Ben Zhong


    A class of new amphiphilic nanocapsules entangled with organometallic coordination polymers has been developed for the first time. Poly(2-(N,N-dimethyl amino)ethyl methacrylate)-b-polystyrene capped with β-cyclodextrin (β-CD) (CD-PDMAEMA-b-PS) is first synthesized using sequent RAFT polymerization of styrene and 2-(N,N-dimethyl amino)ethyl methacrylate with xanthate modified β-CD as chain transfer agent. The end group of β-CD is allowed to include 4,4'-bipyridine through host-guest inclusion to yield PDMAEMA-b-PS terminated with an inclusion complex of β-CD and bipyridine (bpy-PDMAEMA-b-PS), which is then used as surfactant to prepare emulsion droplets in toluene/water mixture. Upon addition of Ni(II), bipyridine coordinates with Ni(II) to form coordination polymers in the periphery of emulsion droplets, affording amphiphilic capsules entangled with organometallic coordination polymers, as confirmed by GPC, (1)H NMR, SEM, TEM, DLS, and so on. The organometallic coordination polymer capsules are capable of encapsulating organic cargoes. Interestingly, encapsulated cargoes can be extracted from the capsules without damaging the capsules. Such capsules are potential candidates for encapsulating and controlled release of organic cargoes.

  4. Bulk Vitrification Castable Refractory Block Protection Study

    Energy Technology Data Exchange (ETDEWEB)

    Hrma, Pavel R.; Bagaasen, Larry M.; Beck, Andrew E.; Brouns, Thomas M.; Caldwell, Dustin D.; Elliott, Michael L.; Matyas, Josef; Minister, Kevin BC; Schweiger, Michael J.; Strachan, Denis M.; Tinsley, Bronnie P.; Hollenberg, Glenn W.


    Bulk vitrification (BV) was selected for a pilot-scale test and demonstration facility for supplemental treatment to accelerate the cleanup of low-activity waste (LAW) at the Hanford U.S. DOE Site. During engineering-scale (ES) tests, a small fraction of radioactive Tc (and Re, its nonradioactive surrogate) were transferred out of the LAW glass feed and molten LAW glass, and deposited on the surface and within the pores of the castable refractory block (CRB). Laboratory experiments were undertaken to understand the mechanisms of the transport Tc/Re into the CRB during vitrification and to evaluate various means of CRB protection against the deposition of leachable Tc/Re. The tests used Re as a chemical surrogate for Tc. The tests with the baseline CRB showed that the molten LAW penetrates into CRB pores before it converts to glass, leaving deposits of sulfates and chlorides when the nitrate components decompose. Na2O from the LAW reacts with the CRB to create a durable glass phase that may contain Tc/Re. Limited data from a single CRB sample taken from an ES experiment indicate that, while a fraction of Tc/Re is present in the CRB in a readily leachable form, most of the Tc/Re deposited in the refractory is retained in the form of a durable glass phase. In addition, the molten salts from the LAW, mainly sulfates, chlorides, and nitrates, begin to evaporate from BV feeds at temperatures below 800 C and condense on solid surfaces at temperatures below 530 C. Three approaches aimed at reducing or preventing the deposition of soluble Tc/Re within the CRB were proposed: metal lining, sealing the CRB surface with a glaze, and lining the CRB with ceramic tiles. Metal liners were deemed unsuitable because evaluations showed that they can cause unacceptable distortions of the electric field in the BV system. Sodium silicate and a low-alkali borosilicate glaze were selected for testing. The glazes slowed down molten salt condensate penetration, but did little to reduce the

  5. Magnetic propulsion of self-assembled colloidal carpets: efficient cargo transport via a conveyor-belt effect


    Martinez-Pedrero, Fernando; Tierno, Pietro


    We demonstrate a general method to assemble and propel highly maneuverable colloidal carpets which can be steered via remote control in any direction of the plane. These colloidal micropropellers are composed by an ensemble of spinning rotors and can be readily used to entrap, transport, and release biological cargos on command via a hydrodynamic conveyor-belt effect. An efficient control of the cargo transportation combined with remarkable "healing" ability to surpass obstacles demonstrate a...

  6. 46 CFR 32.60-10 - Segregation of cargo; Grade A, B, C, or D-TB/ALL. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Segregation of cargo; Grade A, B, C, or D-TB/ALL. 32.60-10 Section 32.60-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL... 1, 1951 § 32.60-10 Segregation of cargo; Grade A, B, C, or D—TB/ALL. (a) General. The galleys...

  7. [Staphylococcus aureus in bulk milk samples]. (United States)

    Benda, P; Vyletĕlová, M


    In the years 1993-1994 the occurrence of Staphylococcus aureus was investigated in bulk milk samples in the area where a Baby Food Factory at Zábreh in Moravia is located, and in Bruntál, Zlín and Policka districts. Evaluation of the results was based on ECC Directive 92/46, while the dynamics of S. aureus presence was followed for the whole period of observation as well as in the particular seasons. A total of 4,485 samples was processed. Out of these, 50.7% contained less than 100 CFU/ml of S. aureus, 41.4% contained 100-500 CFU/ml, 6.73% 500-2,000 CFU/ml and 1.14% contained more than 2,000 CFU/ml (Fig. 1). The samples were divided into three categories: private new-established farms, cooperative and State-owned enterprises in the area of the Zábĕh Factory and others (Zlín, Bruntál and Policka districts). There were highly significant differences in the content of staphylococci (P = 0.01%) between the three categories of samples. Ninety-eight percent of samples from private farms, 96% samples from the Zábreh Factory area and 85% of the other samples comply with the regulation EEC 92/64 (Tab. I) for raw cow's milk for the manufacture of products "made with raw milk" whose manufacturing process does not involve any heat treatment (Fig. 2). The occurrence of S. aureus in the Zábreh Factory area shows an expressive seasonal dynamics (P = 0.005%) with maximum values in winter months (December-March) and minimum values in summer months (July-October)-Fig. 3. The same relationship can be seen on more extensive data files for the particular producers (Fig. 4).(ABSTRACT TRUNCATED AT 250 WORDS)

  8. Xerophilic mycopopulations of teas in bulk

    Directory of Open Access Journals (Sweden)

    Škrinjar Marija M.


    Full Text Available d.o.o., Novi Sad AU Krunić Vesna J. AF EKOLd.o.o., Novi Sad KW teas % mould contamination % thermal treatment KR nema Other the water, tea is the most popular beverage in the world today. They are used for ages, in the beginning as refreshing drinks, and later more for their healing properties. Teas have been demonstrated to show antioxidative, anti-carcinogenic, and anti-microbial properties. Considering that the teas, during the production, are not treated with any temperature, there is high risk for contamination with different type of microorganisms, especially with moulds. Moulds are ubiquitously distributed in nature and their spores can be found in the atmosphere even at high altitudes and under favorable conditions of temperature and humidity, moulds grow on many commodities including cereals, oil seeds, nuts, herbs and spices. Most of them are potential producers of mycotoxins which present a real hazard to human health. The aim of this work was to investigate total mould count and to identify moulds isolated from teas in bulk, than from teas treated with hot, sterile, distilled water and from the tea filtrates. Tested teas were peppermint, sage, yarrow, black tea, bearberry, lemon balm, mixture of teas from Zlatibor. In teas in balk was observed high contamination with different kinds of moulds (1.84-4.55 cfu/g, such as Aspergillus awamori, A. lovaniensis, A niger, A. phoenicus, A. repens, A. restrictus, A. sydowii, A. versicolor, Eurotium amstelodami, E. chevalieri, E. herbariorum, Penicillium chrysogenum, and Scopulariopsis brevicaulis. The most frequent were species from Aspergillus and Eurotium genera. Thermal treatment with hot, sterile, distilled water reduced the number of fungal colonies. Aspergillus awamori was the most resistant and appeared in six samples of filtrates of tea, Aspergillus niger in one sample and Penicillium chrysogenum in one sample.

  9. Silicon bulk micromachined hybrid dimensional artifact.

    Energy Technology Data Exchange (ETDEWEB)

    Claudet, Andre A.; Tran, Hy D.; Bauer, Todd Marks; Shilling, Katherine Meghan; Oliver, Andrew David


    A mesoscale dimensional artifact based on silicon bulk micromachining fabrication has been developed and manufactured with the intention of evaluating the artifact both on a high precision coordinate measuring machine (CMM) and video-probe based measuring systems. This hybrid artifact has features that can be located by both a touch probe and a video probe system with a k=2 uncertainty of 0.4 {micro}m, more than twice as good as a glass reference artifact. We also present evidence that this uncertainty could be lowered to as little as 50 nm (k=2). While video-probe based systems are commonly used to inspect mesoscale mechanical components, a video-probe system's certified accuracy is generally much worse than its repeatability. To solve this problem, an artifact has been developed which can be calibrated using a commercially available high-accuracy tactile system and then be used to calibrate typical production vision-based measurement systems. This allows for error mapping to a higher degree of accuracy than is possible with a glass reference artifact. Details of the designed features and manufacturing process of the hybrid dimensional artifact are given and a comparison of the designed features to the measured features of the manufactured artifact is presented and discussed. Measurement results from vision and touch probe systems are compared and evaluated to determine the capability of the manufactured artifact to serve as a calibration tool for video-probe systems. An uncertainty analysis for calibration of the artifact using a CMM is presented.

  10. 76 FR 13313 - Hazardous Materials: Cargo Tank Motor Vehicle Loading and Unloading Operations (United States)


    ... hazardous material incident data. The proposal aims to reduce the overall number of hazardous material... practices for loading and unloading operations involving bulk packagings used to transport hazardous... applicable to bulk loading and unloading operations, summarized the results of a public workshop PHMSA hosted...

  11. 30 CFR 56.6802 - Bulk delivery vehicles. (United States)


    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Explosives Maintenance § 56.6802 Bulk delivery vehicles. No welding or cutting shall be performed on a bulk delivery vehicle...

  12. 77 FR 12293 - PCBs Bulk Product v. Remediation Waste (United States)


    ... Docket, EPA/DC, EPA West, Room 3334, 1301 Constitution Ave. NW., Washington, DC 20460. The Public Reading... telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the RCRA Docket... defined as PCB bulk product waste in 40 CFR 761.3. The definition of PCB bulk product waste includes ``non...

  13. Bulk metallic glasses: A new class of engineering materials

    Indian Academy of Sciences (India)

    A number of processes is available to synthesise bulk metallic glasses. The crystallisation behaviour and mechanical properties of these alloys pose interesting scientific questions. Upon crystallisation many of these glasses transform to bulk nanocrystals and nanoquasicrystals. A detailed study of the structure and the ...

  14. Simulation-integrated Design of Dry Bulk Terminals

    NARCIS (Netherlands)

    Van Vianen, T.A.


    To meet the expected increase of seaborne trade flows for coal and iron ore dry bulk terminals need to be designed or expanded. A comprehensive design method for dry bulk terminals is missing. Designs are currently based on rules-of-thumb, practical experiences and average values for specific design

  15. Influence of bulk dielectric polarization upon PD transients

    DEFF Research Database (Denmark)

    Pedersen, Aage; Crichton, George C; McAllister, Iain Wilson


    associated with the actual space charge in the void, and one related to changes in the bulk polarization brought about by changes in the field external to the void due to this space charge. The magnitude of the induced charge and its components are discussed in relation to a heterogeneous bulk dielectric...

  16. A new approximate sum rule for bulk alloy properties (United States)

    Bozzolo, Guillermo; Ferrante, John


    A new, approximate sum rule is introduced for determining bulk properties of multicomponent systems, in terms of the pure components properties. This expression is applied for the study of lattice parameters, cohesive energies, and bulk moduli of binary alloys. The correct experimental trends (i.e., departure from average values) are predicted in all cases.

  17. Bianchi Type-I bulk viscous fluid string dust magnetized ...

    Indian Academy of Sciences (India)

    Bianchi Type-I magnetized bulk viscous fluid string dust cosmological model is investigated. To get a determinate model, we have assumed the conditions and = constant where is the shear, the expansion in the model and the coefficient of bulk viscosity. The behaviour of the model in the presence and ...

  18. Advanced and new developments in bulk metal forming

    DEFF Research Database (Denmark)

    Bay, Niels; Wanheim, Tarras; Ravn, Bjarne Gottlieb


    Increasing demands to manufacturing industry of faster, better and cheaper production has intensified the research and development of bulk metal forming. The present paper gives examples on European industrial research on secondary bulk metal forming processes. The R&D follows three lines...

  19. Bulk viscosity of accretion disks around non rotating black holes (United States)

    Moeen Moghaddas, M.


    In this paper, we study the Keplerian, relativistic accretion disks around the non rotating black holes with the bulk viscosity. Many of authors studied the relativistic accretion disks around the black holes, but they ignored the bulk viscosity. We introduce a simple method to calculate the bulk in these disks. We use the simple form for the radial component of the four velocity in the Schwarzschild metric, then the other components of the four velocity and the components of the shear and the bulk tensor are calculated. Also all components of the bulk viscosity, the shear viscosity and stress tensor are calculated. It is seen that some components of the bulk tensor are comparable with the shear tensor. We calculate some of the thermodynamic quantities of the relativistic disks. Comparison of thermodynamic quantities shows that in some states influences of the bulk viscosity are important, especially in the inner radiuses. All calculations are done analytically and we do not use the boundary conditions. Finally, we find that in the relativistic disks around the black holes, the bulk viscosity is non-negligible in all the states.

  20. Role of bulking agents in bladder exstrophyepispadias complexes ...

    African Journals Online (AJOL)

    Three out of five girls had improved bladder prolapse. There was no Complication, infection or migration of bulking agents. Patients had increased in soft tissue according to MRI. Conclusion: Using bulking agents is a good alternative to sling pelvic floor not only cosmetically but also for ease of patients and operation.

  1. Effect of Bulk and Interfacial Rheological Properties on Bubble Dissolution

    NARCIS (Netherlands)

    Kloek, W.; Vliet, van T.; Meinders, M.


    This paper describes theoretical calculations of the combined effect of bulk and interracial rheological properties on dissolution behavior of a bubble in an infinite medium at saturated conditions. Either bulk or interracial elasticity can stop the bubble dissolution process, and stability criteria

  2. Modelling and Forecasting in the Dry Bulk Shipping Market

    NARCIS (Netherlands)

    Chen, S.


    This dissertation proposes strategies not only for modelling price behavior in the dry bulk market, but also for modelling relationships between economic and technical variables of dry bulk ships, by using modern time series approaches, Monte Carlo simulation and other economic techniques. The time

  3. Bulk modulus of metals according to structureless pseudopotential ...

    African Journals Online (AJOL)

    structureless pseudopotential model was fully developed. The developed method was used to calculate the bulk modulus and kinetic energy contribution to the bulk modulus of 46 elemental metals. The results obtained were compared with experimental values and their variation with electron density parameter was studied ...

  4. Nucleation of bulk superconductivity close to critical magnetic fields

    DEFF Research Database (Denmark)

    Fournais, Søren; Kachmar, Ayman


    threshold value of the applied magnetic field for which bulk superconductivity contributes to the leading order of the energy. Furthermore, the energy of the bulk is related to that of the Abrikosov problem in a periodic lattice. A key ingredient of the proof is a novel L∞ -bound which is of independent...

  5. 27 CFR 24.301 - Bulk still wine record. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bulk still wine record. 24..., DEPARTMENT OF THE TREASURY LIQUORS WINE Records and Reports § 24.301 Bulk still wine record. A proprietor who produces or receives still wine in bond, (including wine intended for use as distilling material or vinegar...

  6. Bulk forming of industrial micro components in conventional metals and bulk metallic glasses

    DEFF Research Database (Denmark)

    Arentoft, Mogens; Paldan, Nikolas Aulin; Eriksen, Rasmus Solmer


    For production of micro components in large numbers, forging is an interesting and challenging process. The conventional metals like silver, steel and aluminum often require multi-step processes, but high productivity and increased strength justify the investment. As an alternative, bulk metallic...... glasses will at elevated temperatures behave like a highly viscous liquid, which can easily form even complicated geometries in 1 step. The strengths and limitations of forming the 2 materials are analyzed for a micro 3D component in a silver alloy and an Mg-Cu-Y BMG. ©2007 American Institute of Physics...

  7. Bulk viscosity, interaction and the viability of phantom solutions

    CERN Document Server

    Leyva, Yoelsy


    We study the dynamics of a bulk viscosity model in the Eckart approach for a spatially flat Friedmann-Robertson-Walker (FRW) universe. We have included radiation and dark energy, assumed as perfect fluids, and dark matter treated as an imperfect fluid having bulk viscosity. We also introduce an interaction term between the dark matter and dark energy components. Considering that the bulk viscosity is proportional to the dark matter energy density and imposing a complete cosmological dynamics, we find bounds on the bulk viscosity in order to reproduce a matter-dominated era (MDE). This constraint is independent of the interaction term. Some late time phantom solutions are mathematically possible. However, the constraint imposed by a MDE restricts the interaction parameter, in the phantom solutions, to a region consistent with a null value, eliminating the possibility of late time stable solutions with $w<-1$. From the different cases that we study, the only possible scenario, with bulk viscosity and interac...

  8. Carbon nanotubes grown on bulk materials and methods for fabrication (United States)

    Menchhofer, Paul A [Clinton, TN; Montgomery, Frederick C [Oak Ridge, TN; Baker, Frederick S [Oak Ridge, TN


    Disclosed are structures formed as bulk support media having carbon nanotubes formed therewith. The bulk support media may comprise fibers or particles and the fibers or particles may be formed from such materials as quartz, carbon, or activated carbon. Metal catalyst species are formed adjacent the surfaces of the bulk support material, and carbon nanotubes are grown adjacent the surfaces of the metal catalyst species. Methods employ metal salt solutions that may comprise iron salts such as iron chloride, aluminum salts such as aluminum chloride, or nickel salts such as nickel chloride. Carbon nanotubes may be separated from the carbon-based bulk support media and the metal catalyst species by using concentrated acids to oxidize the carbon-based bulk support media and the metal catalyst species.

  9. Bulk viscosity of spin-one color superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Sa' d, Basil A.


    The bulk viscosity of several quark matter phases is calculated. It is found that the effect of color superconductivity is not trivial, it may suppress, or enhance the bulk viscosity depending on the critical temperature and the temperature at which the bulk viscosity is calculated. Also, is it found that the effect of neutrino-emitting Urca processes cannot be neglected in the consideration of the bulk viscosity of strange quark matter. The results for the bulk viscosity of strange quark matter are used to calculate the r-mode instability window of quark stars with several possible phases. It is shown that each possible phase has a different structure for the r-mode instability window. (orig.)

  10. Stability of bulk metallic glass structure

    Energy Technology Data Exchange (ETDEWEB)

    Jain, H.; Williams, D.B.


    The fundamental origins of the stability of the (Pd-Ni){sub 80}P{sub 20} bulk metallic glasses (BMGs), a prototype for a whole class of BMG formers, were explored. While much of the properties of their BMGs have been characterized, their glass-stability have not been explained in terms of the atomic and electronic structure. The local structure around all three constituent atoms was obtained, in a complementary way, using extended X-ray absorption fine structure (EXAFS), to probe the nearest neighbor environment of the metals, and extended energy loss fine structure (EXELFS), to investigate the environment around P. The occupied electronic structure was investigated using X-ray photoelectron spectroscopy (XPS). The (Pd-Ni){sub 80}P{sub 20} BMGs receive their stability from cumulative, and interrelated, effects of both atomic and electronic origin. The stability of the (Pd-Ni){sub 80}P{sub 20} BMGs can be explained in terms of the stability of Pd{sub 60}Ni{sub 20}P{sub 20} and Pd{sub 30}Ni{sub 50}P{sub 20}, glasses at the end of BMG formation. The atomic structure in these alloys is very similar to those of the binary phosphide crystals near x=0 and x=80, which are trigonal prisms of Pd or Ni atoms surrounding P atoms. Such structures are known to exist in dense, randomly-packed systems. The structure of the best glass former in this series, Pd{sub 40}Ni{sub 40}P{sub 20} is further described by a weighted average of those of Pd{sub 30}Ni{sub 50}P{sub 20} and Pd{sub 60}Ni{sub 20}P{sub 20}. Bonding states present only in the ternary alloys were found and point to a further stabilization of the system through a negative heat of mixing between Pd and Ni atoms. The Nagel and Tauc criterion, correlating a decrease in the density of states at the Fermi level with an increase in the glass stability, was consistent with greater stability of the Pd{sub x}Ni{sub (80-x)}P{sub 20} glasses with respect to the binary alloys of P. A valence electron concentration of 1.8 e/a, which

  11. 78 FR 72841 - List of Bulk Drug Substances That May Be Used in Pharmacy Compounding; Bulk Drug Substances That... (United States)


    ... Used in Pharmacy Compounding; Bulk Drug Substances That May Be Used To Compound Drug Products in... Administration (FDA or Agency) is withdrawing the proposed rule to list bulk drug substances used in pharmacy... Pharmacopoeia chapter on pharmacy compounding; (II) if such a monograph does not exist, are drug substances that...

  12. Application of the penetration theory for gas - Liquid mass transfer without liquid bulk : Differences with system with a bulk

    NARCIS (Netherlands)

    van Elk, E. P.; Knaap, M. C.; Versteeg, G. F.


    Frequently applied micro models for gas-liquid mass transfer all assume the presence of a liquid bulk. However, some systems are characterized by the absence of a liquid bulk, a very thin layer of liquid flows over a solid surface. An example of such a process is absorption in a column equipped with

  13. Bulk-mediated surface transport in the presence of bias (United States)

    Berezhkovskii, Alexander M.; Dagdug, Leonardo; Bezrukov, Sergey M.


    Surface transport, when the particle is allowed to leave the surface, travel in the bulk for some time, and then return to the surface, is referred to as bulk-mediated surface transport. Recently, we proposed a formalism that significantly simplifies analysis of bulk-mediated surface diffusion [A. M. Berezhkovskii, L. Dagdug, and S. M. Bezrukov, J. Chem. Phys. 143, 084103 (2015)]. Here this formalism is extended to bulk-mediated surface transport in the presence of bias, i.e., when the particle has arbitrary drift velocities on the surface and in the bulk. A key advantage of our approach is that the transport problem reduces to that of a two-state problem of the particle transitions between the surface and the bulk. The latter can be solved with relative ease. The formalism is used to find the Laplace transforms of the first two moments of the particle displacement over the surface in time t at arbitrary values of the particle drift velocities and diffusivities on the surface and in the bulk. This allows us to analyze in detail the time dependence of the effective drift velocity of the particle on the surface, which can be highly nontrivial.

  14. Engineering Nanostructural Routes for Enhancing Thermoelectric Performance: Bulk to Nanoscale. (United States)

    Mohanraman, Rajeshkumar; Lan, Tian-Wey; Hsiung, Te-Chih; Amada, Dedi; Lee, Ping-Chung; Ou, Min-Nan; Chen, Yang-Yuan


    Thermoelectricity is a very important phenomenon, especially its significance in heat-electricity conversion. If thermoelectric devices can be effectively applied to the recovery of the renewable energies, such as waste heat and solar energy, the energy shortage, and global warming issues may be greatly relieved. This review focusses recent developments on the thermoelectric performance of a low-dimensional material, bulk nanostructured materials, conventional bulk materials etc. Particular emphasis is given on, how the nanostructure in nanostructured composites, confinement effects in one-dimensional nanowires and doping effects in conventional bulk composites plays an important role in ZT enhancement.

  15. Eco Issues in Bulk Materials Handling Technologies in Ports

    Directory of Open Access Journals (Sweden)

    Nenad Zrnić


    Full Text Available This paper deals with eco issues in bulk materials handling in ports. Solid, free-flowing materials are said to be in bulk. Bulk materials handling is very difficult, because it incorporates all the features of liquids, gasses and mass solids. Energy efficiency, dust emissions in nearby environment, dust explosions, jamming, noise, handling of hazardous materials and protection of materials from contamination are issues that will be considered in this paper. Here are also presented possible solutions for some of these issues

  16. Tunable bulk polaritons of graphene-based hyperbolic metamaterials. (United States)

    Zhang, Liwei; Zhang, Zhengren; Kang, Chaoyang; Cheng, Bei; Chen, Liang; Yang, Xuefeng; Wang, Jian; Li, Weibing; Wang, Baoji


    The tunable hyperbolic metamaterial (HMM) based on the graphene-dielectric layered structure at THz frequency is presented, and the surface and bulk polaritons of the graphene-based HMM are theoretically studied. It is found that the dispersions of the polaritons can be tuned by varying the Fermi energy of graphene sheets, the graphene-dielectric layers and the layer number of graphene sheets. In addition, the highly confined bulk polariton mode can be excited and is manifested in an attenuated total reflection configuration as a sharp drop in the reflectance. Such properties can be used in tunable optical reflection modulation with the assistance of bulk polaritons.

  17. El acceso a los cargos de gobierno de la audiencia de Quito (1701-1750

    Directory of Open Access Journals (Sweden)

    Sanz Tapia, Ángel


    Full Text Available Study oft the designations of the posts of government (“presidencias”, “gobiernos”, ”alcaldías Mayores” y “corregimientos” in the “Audiencia” of Quito and its connection with the way to get them (by a service given, by a merit, by money…. The appointments were effected from Madrid during the first half of the 18th century. Analysis in detail of the posts and of the amounts of money that were paid as a benefit in order to get the post as well as some references to the same circumstances in the High Court at the end of the rign of Carlos II (1674-1700. Location of the designated personages, information about the dedication to their work and about their social standing. In conclusion: Two in three offices were got by money; the number of creoles in the Spanish - American governments increased in relation to the previous stage.

    Estudio de las provisiones de cargos de gobierno (presidencias audienciales, gobernaciones, alcaldías mayores y corregimientos de la audiencia de Quito efectuadas desde Madrid en relación con su modo de acceso (por méritos, por dinero, etc., durante la primera mitad del siglo XVIII. Análisis detallado de los cargos, cuantías abonadas por concepto de “beneficio”, y referencias a las mismas circunstancias de la audiencia en la etapa final de Carlos II (1674-1700. Localización de los personajes provistos y referencias sobre dedicación y categoría social. Conclusiones: 2 de cada 3 oficios se consiguieron mediante donativo pecuniario; hay un aumento del número de criollos en los cargos de gobierno indianos analizados en relación con la etapa precedente.


    Directory of Open Access Journals (Sweden)

    MUNTEANU Ildikó Renata


    Full Text Available The authors are proposing an additional fire protection solution (semi-passive for cargo ships, by inserting in the tubular strength structure (hollow section, some rectangular, thin wall pipes manufactured of copper alloy, filled with cooling fluid, that, once the fire bursts, it will be activated (i.e. will be pumped into a closed circuit; this closed system contains also a well dimensioned radiator. This innovative solution could bring improvements with regard to the classic one, of intumescent paints, by extending the safe period for evacuating people and goods.

  19. Risk Analysis on Ship Wreck and Container Cargo to Ship Navigation

    Directory of Open Access Journals (Sweden)

    Muhammad Badrus Zaman


    Full Text Available Wreck of a ship is an incident that must be avoided. Ship accidents are generally caused by a several cases, such as human error, natural disaster, technical errors, missed communication, poor condition of the ship, and many more. Ship wreckage have huge impact for ship navigation, environment, economics, and others. Those impact have many disadvantages for the shipowners, and also for environment. For examples the fuel spills that pollute the environment, make disturbance to sailing ship because the track for those navigation is blocked by the ship wreck and their cargo especially on shallow location (<50 m. These research will discuss the effect the container when it is floats on the sea and its interference other ships. The main objective of this study is to present a risk assessment on the environmental impact of the wreck and container cargo. Wrecks on the seabed is likely to pose a risk to passing ships. container and its contents as well as the possibility of refloat, and also their environmental risks emanating from the wreck and container cargo, such as fuels, lubricants, and chemical cargo. Variations scenario is a collision between ships that pass by floating containers. The frequency of refloating container, and the consequences of the passing ship depends on several factors, which will be the subject of research. However, because of the frequency of refloating containers is unlikely, then the risk is low and does not pose a danger to navigation. These risk assessment using risk matrix 5x5 which is the combined value of the frequency and consequences of the incident. The results of this study indicate the level of risk, whether the risk is accepted, not accepted or received by considering the costs and benefits (ALARP. To consequence, there are two parameters which energy is absorbed and the penetration occurs. The absorbed energy is divided into two, namely the energy absorbed by ship and the energy absorbed by containers. In this

  20. Mission Design Considerations for Mars Cargo of the Human Spaceflight Architecture Team's Evolvable Mars Campaign (United States)

    Sjauw, Waldy K.; McGuire, Melissa L.; Freeh, Joshua E.


    Recent NASA interest in human missions to Mars has led to an Evolvable Mars Campaign by the agency's Human Architecture Team. Delivering the crew return propulsion stages and Mars surface landers, SEP based systems are employed because of their high specific impulse characteristics enabling missions requiring less propellant although with longer transfer times. The Earth departure trajectories start from an SLS launch vehicle delivery orbit and are spiral shaped because of the low SEP thrust. Previous studies have led to interest in assessing the divide in trip time between the Earth departure and interplanetary legs of the mission for a representative SEP cargo vehicle.



    Ariel Soltura Laseria; Armando Cuesta Santos


    En el trabajo se presenta una tecnología para la determinación de los perfiles de cargo por competencias en las organizaciones cubanas con base científica, fundamentada en la creciente necesidad de dirigir los esfuerzos individuales hacia el cumplimiento de la estrategia. La tecnología provee a las organizaciones de una forma de determinar la estructura de competencias que ha de adoptar para satisfacer las demandas o necesidades de clientes o usuarios, estado, proveedores y sociedad, en ...


    Directory of Open Access Journals (Sweden)

    I. M. Tsarenkova


    Full Text Available Рurpose. The article is aimed to develop and adapt the theoretical and methodological foundations for improving logistics system of cargo delivery by road transport in the framework of the scientific support of formation processes of transport-logistical system of the country. Methodology. The theory of system functioning control requires formalization of connections within the system. The qualitative and quantitative characteristics of entity were performed and the regularities of elements interaction in the system of road goods transportation were found out. The role of the road in transport industry and the influence of transportation and logistics space on the road itself in the process of its functioning were clarified. In the study of this topic the system approach, methods of synthesis and rational problem solving, theory of mass service were used. Findings. The work presents the highway as an element of the cargo transportation system that will make it possible to increase its economic efficiency in a constantly changing environment of transportation and logistics space according to the chosen criterion, the lower total costs to promote material flow. Theoretical-methodological bases of perfection of logistics system of cargo delivery by road transport include substantiation for the use of logistics as an effective control element to reduce the costs associated with goods transportation. They are distinguished by the presence of evidence-based methods for calculating the timing and sequence of execution of road works, logistic integration involved in the carriage of goods of the enterprises, structure and volume of material and accompanying flows and the formation of the logistics chain of its promotion. Originality. The road is represented by the link of single integral process of creation and management of the material flows. We propose formation of sub-system of the elements of road and transportation components with their further

  3. Cargo Securing During Transport Depending on the Type of a Road (United States)

    Vlkovský, Martin; Šmerek, Michal; Michálek, Jaroslav


    The article is concerned with the evaluation of a transport experiment conducted in the Czech Republic in order to prove the inappropriateness of the input data used for the purpose of cargo securing in vehicles. For the experiment, a TATRA truck was used. In a statistical evaluation, an overview of basic statistical characteristics, including an interpretation of significant values, is provided. In the article, a model of loading is presented illustrating the problem associated with the application of average – normative – values of acceleration coefficients when calculating inertial forces acting during transport on different types of roads.

  4. Morintides: cargo-free chitin-binding peptides from Moringa oleifera. (United States)

    Kini, Shruthi G; Wong, Ka H; Tan, Wei Liang; Xiao, Tianshu; Tam, James P


    Hevein-like peptides are a family of cysteine-rich and chitin-binding peptides consisting of 29-45 amino acids. Their chitin-binding property is essential for plant defense against fungi. Based on the number of cysteine residues in their sequences, they are divided into three sub-families: 6C-, 8C- and 10C-hevein-like peptides. All three subfamilies contain a three-domain precursor comprising a signal peptide, a mature hevein-like peptide and a C-terminal domain comprising a hinge region with protein cargo in 8C- and 10C-hevein-like peptides. Here we report the isolation and characterization of two novel 8C-hevein-like peptides, designated morintides (mO1 and mO2), from the drumstick tree Moringa oleifera, a drought-resistant tree belonging to the Moringaceae family. Proteomic analysis revealed that morintides comprise 44 amino acid residues and are rich in cysteine, glycine and hydrophilic amino acid residues such as asparagine and glutamine. Morintides are resistant to thermal and enzymatic degradation, able to bind to chitin and inhibit the growth of phyto-pathogenic fungi. Transcriptomic analysis showed that they contain a three-domain precursor comprising an endoplasmic reticulum (ER) signal sequence, a mature peptide domain and a C-terminal domain. A striking feature distinguishing morintides from other 8C-hevein-like peptides is a short and protein-cargo-free C-terminal domain. Previously, a similar protein-cargo-free C-terminal domain has been observed only in ginkgotides, the 8C-hevein-like peptides from a gymnosperm Ginkgo biloba. Thus, morintides, with a cargo-free C-terminal domain, are a stand-alone class of 8C-hevein-like peptides from angiosperms. Our results expand the existing library of hevein-like peptides and shed light on molecular diversity within the hevein-like peptide family. Our work also sheds light on the anti-fungal activity and stability of 8C-hevein-like peptides.


    Directory of Open Access Journals (Sweden)

    Zulfaidah Ariany


    Full Text Available This article titled is equipment load factor on cargo ship LCT type by taking a case study on Lestari Abadi ship03, the study aims to predict electric consumption calculation of LCT ship’s type which concerning with thenumber and type of generator; effective and efficience power consumption, safe and effective electric instalationand existing panel. So, minimum required output electric installed to Kapal Lestari Abadi 03 has to 150KW, asspecification performed by caterpillar C9TA 150KW, 188KVA, 1500rpm, 50Hz and 0.8.

  6. Advanced Manufacturing Technologies (AMT): Bulk Metallic Glass Element (United States)

    National Aeronautics and Space Administration — The first major objective of the ‘Bulk Metallic Glasses (BMGs) for Space Applications’ project is to raise the technology readiness level dry lubricated,...

  7. Nondestructive Method for Bulk Chemical Characterization of Barred Olivine Chondrules (United States)

    Montoya-Perez, M. A.; Cervantes-de la Cruz, K. E.; Ruvalcaba-Sil, J. L.


    This work develops a bulk chemical characterization of barred olivine chondrules based on the XRF analysis using a portable equipment at the National Research and Conservation Science Laboratory of Cultural Heritage (LANCIC-IF) in Mexico City.

  8. Lazy Evaluation for Concurrent OLTP and Bulk Transactions

    NARCIS (Netherlands)

    Wevers, L.; Huisman, Marieke; van Keulen, Maurice


    Existing concurrency control systems cannot execute transactions with overlapping updates concurrently. This is especially problematic for bulk updates, which usually overlap with all concurrent transactions. To solve this, we have developed a concurrency control mechanism based on lazy evaluation,

  9. Surface Premelting Coupled with Bulk Phase Transitions in Colloidal Crystals (United States)

    Li, Bo; Wang, Feng; Zhou, Di; Cao, Xin; Peng, Yi; Ni, Ran; Liao, Maijia; Han, Yilong


    Colloids have been used as outstanding model systems for the studies of various phase transitions in bulk, but not at interface yet. Here we obtained equilibrium crystal-vapor interfaces using tunable attractive colloidal spheres and studied the surface premelting at the single-particle level by video microscopy. We found that monolayer crystals exhibit a bulk isostructural solid-solid transition which triggers the surface premelting. The premelting is incomplete due to the interruption of a mechanical-instability-induced bulk melting. By contrast, two- or multilayer crystals do not have the solid-solid transition and the mechanical instability, hence they exhibit complete premelting with divergent surface-liquid thickness. These novel interplays between bulk and surface phase transitions cast new lights for both types of transitions.

  10. Efficiency of bulk-heterojunction organic solar cells (United States)

    Scharber, M.C.; Sariciftci, N.S.


    During the last years the performance of bulk heterojunction solar cells has been improved significantly. For a large-scale application of this technology further improvements are required. This article reviews the basic working principles and the state of the art device design of bulk heterojunction solar cells. The importance of high power conversion efficiencies for the commercial exploitation is outlined and different efficiency models for bulk heterojunction solar cells are discussed. Assuming state of the art materials and device architectures several models predict power conversion efficiencies in the range of 10–15%. A more general approach assuming device operation close to the Shockley–Queisser-limit leads to even higher efficiencies. Bulk heterojunction devices exhibiting only radiative recombination of charge carriers could be as efficient as ideal inorganic photovoltaic devices. PMID:24302787

  11. Role of the antiferromagnetic bulk spins in exchange bias

    Energy Technology Data Exchange (ETDEWEB)

    Schuller, Ivan K. [Center for Advanced Nanoscience and Physics Department, University of California San Diego, La Jolla, CA 92093 (United States); Morales, Rafael, E-mail: [Department of Chemical-Physics & BCMaterials, University of the Basque Country UPV/EHU (Spain); IKERBASQUE, Basque Foundation for Science, 48011 Bilbao (Spain); Batlle, Xavier [Departament Física Fonamental and Institut de Nanociència i Nanotecnologia, Universitat de Barcelona, c/ Martí i Franqués s/n, 08028 Barcelona, Catalonia (Spain); Nowak, Ulrich [Department of Physics, University of Konstanz, 78464 Konstanz (Germany); Güntherodt, Gernot [Physics Institute (IIA), RWTH Aachen University, Campus RWTH-Melaten, 52074 Aachen (Germany)


    This “Critical Focused Issue” presents a brief review of experiments and models which describe the origin of exchange bias in epitaxial or textured ferromagnetic/antiferromagnetic bilayers. Evidence is presented which clearly indicates that inner, uncompensated, pinned moments in the bulk of the antiferromagnet (AFM) play a very important role in setting the magnitude of the exchange bias. A critical evaluation of the extensive literature in the field indicates that it is useful to think of this bulk, pinned uncompensated moments as a new type of a ferromagnet which has a low total moment, an ordering temperature given by the AFM Néel temperature, with parallel aligned moments randomly distributed on the regular AFM lattice. - Highlights: • We address the role of bulk antiferromagnetic spins in the exchange bias phenomenon. • Significant experiments on how bulk AFM spins determine exchange bias are highlighted. • We explain the model that accounts for experimental results.

  12. Vacuum Brane and the Bulk Dynamics in Dilatonic Brane World


    Ochiai, H; Sato, K.


    We investigate the dynamics of vacuum brane and the bulk in dilatonic brane world. We present exact dynamical solutions which describe the vacuum dilatonic brane world. We find that the solution has initial singularity and singularity at spatial infinity.

  13. Bulk metallic glass for low noise fluxgate Project (United States)

    National Aeronautics and Space Administration — The team of Prime Photonics, Virginia Tech, and Utron Kinetics propose to demonstrate a method for fabrication of a bulk, amorphous, cobalt-rich material that...

  14. Comunidad, sistema de cargos y proyecto social. Una propuesta analítica de sociedades locales en México

    Directory of Open Access Journals (Sweden)

    Íñigo González de la Fuente


    Full Text Available El presente texto contiene una propuesta de análisis antropológico del sistema de cargos que incluye tanto a comunidades indígenas como no-indígenas. Partiendo del reconocimiento del sistema de cargos como una institución esencialmente heterogénea, se sugiere que, como hipótesis principal, tal institución alimenta una serie de mecanismos que, en sí mismos, potencian los escenarios de interacciones que protagonizan los miembros de la comunidad a través de un conjunto de roles: fomentan que los escenarios puedan ser protagonizados por el mayor número de miembros; propician que tales escenarios se articulen con la mayor frecuencia posible; todo ello con el acuerdo tácito entre protagonistas de que exista rotación de roles entre escenario y escenario. Esta propuesta analítica va a estar estructurada en tres bloques. En primer lugar, se ubican los fenómenos estudiados en torno al sistema de cargos en un continuum de comportamientos tendentes al individualismo y a lo colectivo en sus dos polos. En segundo lugar, se explicita el concepto de comunidad como elemento básico para el estudio de los sistemas de cargos; por último, se propone la idea del proyecto comunitario como denominador común en cuanto a sistemas de cargos se refiere en el área mesoamericana.

  15. Compositional ordering and stability in nanostructured, bulk thermoelectric alloys.

    Energy Technology Data Exchange (ETDEWEB)

    Hekmaty, Michelle A.; Faleev, S.; Medlin, Douglas L.; Leonard, F.; Lensch-Falk, J.; Sharma, Peter Anand; Sugar, J. D.


    Thermoelectric materials have many applications in the conversion of thermal energy to electrical power and in solid-state cooling. One route to improving thermoelectric energy conversion efficiency in bulk material is to embed nanoscale inclusions. This report summarize key results from a recently completed LDRD project exploring the science underpinning the formation and stability of nanostructures in bulk thermoelectric and the quantitative relationships between such structures and thermoelectric properties.

  16. On a bulk queueing system with impatient customers

    Directory of Open Access Journals (Sweden)

    Tadj Lotfi


    Full Text Available We consider a bulk arrival, bulk service queueing system. Customers are served in batches of r units if the queue length is not less than r . Otherwise, the server delays the service until the number of units in the queue reaches or exceeds level r . We assume that unserved customers may get impatient and leave the system. An ergodicity condition and steady-state probabilities are derived. Various system characteristics are also computed.

  17. On a bulk queueing system with impatient customers

    Directory of Open Access Journals (Sweden)

    Lotfi Tadj


    Full Text Available We consider a bulk arrival, bulk service queueing system. Customers are served in batches of r units if the queue length is not less than r. Otherwise, the server delays the service until the number of units in the queue reaches or exceeds level r. We assume that unserved customers may get impatient and leave the system. An ergodicity condition and steady-state probabilities are derived. Various system characteristics are also computed.

  18. Levitation Force Properties of Superconducting Magnetic Bearing Using Bulk Magnet


    齋藤, 友基; 荻原, 宏康


    Type II superconductors can be trapped fluxes at pinning centers. The fluxes-trapping superconductor behaves like a permanent magnet, which is called a "bulk magnet". It is reported that its magnetic field is stronger than that of a usual permanent magnet. We propose a novel levitation system using two sets of superconductors, one of which used the bulk magnets. In this paper, we compared the levitation forces of a usual levitation system with a permanent magnet and the novel levitation syste...

  19. Concentration polarization, surface currents, and bulk advection in a microchannel

    DEFF Research Database (Denmark)

    Nielsen, Christoffer Peder; Bruus, Henrik


    . A remarkable outcome of the investigations is the discovery of strong couplings between bulk advection and the surface current; without a surface current, bulk advection is strongly suppressed. The numerical simulations are supplemented by analytical models valid in the long channel limit as well...... as in the limit of negligible surface charge. By including the effects of diffusion and advection in the diffuse part of the electric double layers, we extend a recently published analytical model of overlimiting current due to surface conduction....

  20. Bulk metallic glasses: A new class of engineering materials


    Basu, Joysurya; Ranganathan, S.


    Bulk glass-forming alloys have emerged over the past fifteen years with attractive properties and technological promise. A number of alloy systems based on lanthanum, magnesium, zirconium, palladium, iron, cobalt and nickel have been discovered. Glass-forming ability depends on various factors like enthalpy of mixing, atomic size and multicomponent alloying. A number of processes is available to synthesise bulk metallic glasses. The crystallisation behaviour and mechanical properties of t...

  1. Financial Reporting of DLA-Owned Bulk Petroleum Products (United States)


    FINANCIAL REPORTING OF DLA-OWNED BULK PETROLEUM PRODUCTS Report No. D-2001-126 May 23, 2001 Office of...34DD MON YYYY") Title and Subtitle Financial Reporting of DLA-Owned Bulk Petroleum Products Contract or Grant Number Program Element Number...the Chief Financial Officers Act of 1990, as amended by the Federal Financial Management Act of 1994. This is the fifth in a series of reports on the

  2. Reliability assessment of bulk electric systems containing large wind farms

    Energy Technology Data Exchange (ETDEWEB)

    Wangdee, Wijarn [Regional System Planning, British Columbia Transmission Corporation, Vancouver (Canada); Billinton, Roy [Power System Research Group, University of Saskatchewan, Saskatoon (Canada)


    Wind power is an intermittent energy source that behaves quite differently than conventional energy sources. Bulk electric system reliability analysis associated with wind energy conversion systems (WECS) provides an opportunity to investigate the reliability benefits when large-scale wind power is injected at specified locations in a bulk electric system. Connecting the WECS to different locations in a bulk system can have different impacts on the overall system reliability depending on the system topology and conditions. Connecting a large-scale WECS to an area which has weak transmission could create system operating constraints and provide less system benefit than connecting it to an area with stronger transmission. This paper investigates bulk electric system transmission constraints associated with large-scale wind farms. The analyses presented in this paper can be used to determine the maximum WECS installed capacity that can be injected at specified locations in a bulk electric system, and assist system planners to create potential transmission reinforcement schemes to facilitate large-scale WECS additions to the bulk system. A sequential Monte Carlo simulation approach is used as this methodology can facilitate a time series modeling of wind speeds, and also provides accurate frequency and duration assessments. An auto-regressive moving average (ARMA) time series model is used to simulate hourly wind speeds. (author)

  3. Accidental SUSY: enhanced bulk supersymmetry from brane back-reaction (United States)

    Burgess, C. P.; van Nierop, L.; Parameswaran, S.; Salvio, A.; Williams, M.


    We compute how bulk loops renormalize both bulk and brane effective interactions for codimension-two branes in 6D gauged chiral supergravity, as functions of the brane tension and brane-localized flux. We do so by explicitly integrating out hyper- and gauge-multiplets in 6D gauged chiral supergravity compactified to 4D on a flux-stabilized 2D rugby-ball geometry, specializing the results of a companion paper, arXiv:1210.3753, to the supersymmetric case. While the brane back-reaction generically breaks supersymmetry, we show that the bulk supersymmetry can be preserved if the amount of brane- localized flux is related in a specific BPS-like way to the brane tension, and verify that the loop corrections to the brane curvature vanish in this special case. In these systems it is the brane-bulk couplings that fix the size of the extra dimensions, and we show that in some circumstances the bulk geometry dynamically adjusts to ensure the supersymmetric BPS-like condition is automatically satisfied. We investigate the robustness of this residual supersymmetry to loops of non-supersymmetric matter on the branes, and show that supersymmetry-breaking effects can enter only through effective brane-bulk interactions involving at least two derivatives. We comment on the relevance of this calculation to proposed applications of codimension-two 6D models to solutions of the hierarchy and cosmological constant problems.

  4. Feasibility Study of Cargo Airship Transportation Systems Powered by New Green Energy Technologies (United States)

    Skuza, Jonathan R.; Park, Yeonjoon; Kim, Hyun Jung; Seaman, Shane T.; King, Glen C.; Choi, Sang H.; Song, Kyo D.; Yoon, Hargsoon; Lee, Kunik


    The development of transportation systems that use new and sustainable energy technologies is of utmost importance due to the possible future shortfalls that current transportation modes will encounter because of increased volume and costs. The introduction and further research and development of new transportation and energy systems by materials researchers at the National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC) and the Department of Transportation are discussed in this Technical Memorandum. In this preliminary study, airship concepts were assessed for cargo transportation using various green energy technologies capable of 24-hour operation (i.e., night and day). Two prototype airships were successfully constructed and tested at LaRC to demonstrate their feasibility: one with commercially available solar cells for operation during the daytime and one with microwave rectennas (i.e., rectifying antennas) developed in-house for night-time operation. The test results indicate the feasibility of a cargo transportation airship powered by new green energy sources and wireless power technology. Future applications will exploit new green energy sources that use materials and devices recently developed or are in the process of being developed at LaRC. These include quantum well SiGe solar cells; low, mid-, and high temperature thermoelectric modules; and wireless microwave and optical rectenna devices. This study examines the need and development of new energy sources for transportation, including the current status of research, materials, and potential applications.

  5. The Complete Exosome Workflow Solution: From Isolation to Characterization of RNA Cargo

    Directory of Open Access Journals (Sweden)

    Jeoffrey Schageman


    Full Text Available Exosomes are small (30–150 nm vesicles containing unique RNA and protein cargo, secreted by all cell types in culture. They are also found in abundance in body fluids including blood, saliva, and urine. At the moment, the mechanism of exosome formation, the makeup of the cargo, biological pathways, and resulting functions are incompletely understood. One of their most intriguing roles is intercellular communication—exosomes function as the messengers, delivering various effector or signaling macromolecules between specific cells. There is an exponentially growing need to dissect structure and the function of exosomes and utilize them for development of minimally invasive diagnostics and therapeutics. Critical to further our understanding of exosomes is the development of reagents, tools, and protocols for their isolation, characterization, and analysis of their RNA and protein contents. Here we describe a complete exosome workflow solution, starting from fast and efficient extraction of exosomes from cell culture media and serum to isolation of RNA followed by characterization of exosomal RNA content using qRT-PCR and next-generation sequencing techniques. Effectiveness of this workflow is exemplified by analysis of the RNA content of exosomes derived from HeLa cell culture media and human serum, using Ion Torrent PGM as a sequencing platform.

  6. The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo.

    Directory of Open Access Journals (Sweden)

    Anna H Chen

    Full Text Available Cyanobacteria play a significant role in the global carbon cycle. In Synechococcuselongatus, the carbon-fixing enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO is concentrated into polyhedral, proteinaceous compartments called carboxysomes.Using live cell fluorescence microscopy, we show that carboxysomes are first detected as small seeds of RuBisCO that colocalize with existing carboxysomes. These seeds contain little or no shell protein, but increase in RuBisCO content over several hours, during which time they are exposed to the solvent. The maturing seed is then enclosed by shell proteins, a rapid process that seals RuBisCO from the cytosol to establish a distinct, solvent-protected microenvironment that is oxidizing relative to the cytosol. These closure events can be spatially and temporally coincident with the appearance of a nascent daughter RuBisCO seed.Carboxysomes assemble in a stepwise fashion, inside-to-outside, revealing that cargo is the principle organizer of this compartment's biogenesis. Our observations of the spatial relationship of seeds to previously formed carboxysomes lead us to propose a model for carboxysome replication via sequential fission, polymerization, and encapsulation of their internal cargo.

  7. The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo. (United States)

    Chen, Anna H; Robinson-Mosher, Avi; Savage, David F; Silver, Pamela A; Polka, Jessica K


    Cyanobacteria play a significant role in the global carbon cycle. In Synechococcuselongatus, the carbon-fixing enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is concentrated into polyhedral, proteinaceous compartments called carboxysomes. Using live cell fluorescence microscopy, we show that carboxysomes are first detected as small seeds of RuBisCO that colocalize with existing carboxysomes. These seeds contain little or no shell protein, but increase in RuBisCO content over several hours, during which time they are exposed to the solvent. The maturing seed is then enclosed by shell proteins, a rapid process that seals RuBisCO from the cytosol to establish a distinct, solvent-protected microenvironment that is oxidizing relative to the cytosol. These closure events can be spatially and temporally coincident with the appearance of a nascent daughter RuBisCO seed. Carboxysomes assemble in a stepwise fashion, inside-to-outside, revealing that cargo is the principle organizer of this compartment's biogenesis. Our observations of the spatial relationship of seeds to previously formed carboxysomes lead us to propose a model for carboxysome replication via sequential fission, polymerization, and encapsulation of their internal cargo.

  8. Centrifugal positive displacement pumps for emergency transfer of high-viscosity petrochemical cargoes

    Energy Technology Data Exchange (ETDEWEB)

    Yates, J.B.; Hackman, D.J.; Tierney, J.M.


    Centrifugal positive displacement pumps for emergency transfer of high-viscosity petrochemical cargoes from tankers which ground or sink may require heating of the cargo to lower its viscosity before it can be pumped. Since the energy needed for heating can be much greater than that required for pumping, and because the flow rate is highly dependent on the oil temperature, the amount of heat added must be optimized. To accurately compare the pumping and heating energy inputs, both must be converted into fuel input. The actual heat input is simply divided by a 75Vertical Bar3< boiler efficiency. Assume that the pumping power comes from a diesel engine consuming 0.4 lb of fuel/bhp at 18,000 Btu/lb and that power is transmitted by an 80Vertical Bar3< efficient hydraulic transmission for an over-all conversion factor of 150 Btu/hp min. Once these conversions are made, the pumping and heating energies can be added directly to find total energy in Btu/min.

  9. The back and forth of cargo exit from the endoplasmic reticulum. (United States)

    Geva, Yosef; Schuldiner, Maya


    Endoplasmic reticulum (ER) to Golgi trafficking is an essential step in sorting mature, correctly folded, processed and assembled proteins (cargo) from immature proteins and ER-resident proteins. However, the mechanisms governing trafficking selectivity, specificity and regulation are not yet fully understood. To date, three complementary mechanisms have been described that enable regulation of this trafficking step: ER retention of immature proteins in the ER; selective uptake of fully mature proteins into Golgi-bound vesicles; and retrieval from the Golgi of immature cargo that has erroneously exited the ER. Together, these three mechanisms allow incredible specificity and enable the cell to carry out protein quality control and regulate protein processing, oligomerization and expression. This review will focus on the current knowledge of selectivity mechanisms acting during the ER-to-Golgi sorting step and their significance in health and disease. The review will also highlight several key questions that have remained unanswered and discuss the future frontiers. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Xuefeng; Hurley, James H. (NIH)


    VHS (Vps27, Hrs, and STAM) domains occur in ESCRT-0 subunits Hrs and STAM, GGA adapters, and other trafficking proteins. The structure of the STAM VHS domain-ubiquitin complex was solved at 2.6 {angstrom} resolution, revealing that determinants for ubiquitin recognition are conserved in nearly all VHS domains. VHS domains from all classes of VHS-domain containing proteins in yeast and humans, including both subunits of ESCRT-0, bound ubiquitin in vitro. ESCRTs have been implicated in the sorting of Lys63-linked polyubiquitinated cargo. Intact human ESCRT-0 binds Lys63-linked tetraubiquitin 50-fold more tightly than monoubiquitin, though only 2-fold more tightly than Lys48-linked tetraubiquitin. The gain in affinity is attributed to the cooperation of flexibly connected VHS and UIM motifs of ESCRT-0 in avid binding to the polyubiquitin chain. Mutational analysis of all the five ubiquitin-binding sites in yeast ESCRT-0 shows that cooperation between them is required for the sorting of the Lys63-linked polyubiquitinated cargo Cps1 to the vacuole.


    Directory of Open Access Journals (Sweden)

    Parlindungan Manik


    Full Text Available Kapal general cargo  adalah kapal yang mengangkut bermacam-macam muatan berupa barang.Barang yang diangkut biasanya merupakan barang yang sudah dikemas.Kapal general cargo dilengkapi dengan crane pengangkut barang untuk memudahkan bongkar-muat muatan. Pada penelitian ini direncanakan desain lambung kapal. Ukuran utama kapal didapatkan dengan menggunakan metode regresi yang didasarkan pada data 5 kapal pembanding. Dari ukuran utama yang didapat kemudian dilakukan pembuatan rencana garis, rencana umum, analisa hidrostatik, analisa stabilitas dan analisa olah gerak kapal yang sesuai dengan standar IMO. Setelah dilakukan analisa dengan menggunakan metode regresi yang didasarkan pada data 5 kapal pembanding yang diambil dari Register Of Ship2002-03LR (Lloyd’s Register dihasilkan alternatif ukuran utama kapal, yaitu dengan panjang kapal keseluruhan (Loa = 62,46 m, panjang kapal (Lpp = 57,95 m, lebar kapal (B = 12,26 m, tinggi kapal (H = 6,49 m, sarat kapal (T = 3,85 m, dan kecepatan kapal (Vd = 11 knot. Pada kecepatan maksimal 11 knot hambatan yang di terima sebesar = 66,76 KN dan power sebesar 506,3667 Hp. Nilai GZ  maksimum kapal = 3,369 m.deg dan nilai GM awal = 4,021 m.Gerakan heaving maksimum = 1,086 m, gerakan rolling maksimum =14,15°, dan gerakan pitching maksimum = 3,02°

  12. Microemulsion-Based Soft Bacteria-Driven Microswimmers for Active Cargo Delivery. (United States)

    Singh, Ajay Vikram; Hosseinidoust, Zeinab; Park, Byung-Wook; Yasa, Oncay; Sitti, Metin


    Biohybrid cell-driven microsystems offer unparalleled possibilities for realization of soft microrobots at the micron scale. Here, we introduce a bacteria-driven microswimmer that combines the active locomotion and sensing capabilities of bacteria with the desirable encapsulation and viscoelastic properties of a soft double-micelle microemulsion for active transport and delivery of cargo (e.g., imaging agents, genes, and drugs) to living cells. Quasi-monodisperse double emulsions were synthesized with an aqueous core that encapsulated the fluorescence imaging agents, as a proof-of-concept cargo in this study, and an outer oil shell that was functionalized with streptavidin for specific and stable attachment of biotin-conjugated Escherichia coli. Motile bacteria effectively propelled the soft microswimmers across a Transwell membrane, actively delivering imaging agents (i.e., dyes) encapsulated inside of the micelles to a monolayer of cultured MCF7 breast cancer and J744A.1 macrophage cells, which enabled real-time, live-cell imaging of cell organelles, namely mitochondria, endoplasmic reticulum, and Golgi body. This in vitro model demonstrates the proof-of-concept feasibility of the proposed soft microswimmers and offers promise for potential biomedical applications in active and/or targeted transport and delivery of imaging agents, drugs, stem cells, siRNA, and therapeutic genes to live tissue in in vitro disease models (e.g., organ-on-a-chip devices) and stagnant or low-flow-velocity fluidic regions of the human body.

  13. Life Science on the International Space Station Using the Next Generation of Cargo Vehicles (United States)

    Robinson, J. A.; Phillion, J. P.; Hart, A. T.; Comella, J.; Edeen, M.; Ruttley, T. M.


    With the retirement of the Space Shuttle and the transition of the International Space Station (ISS) from assembly to full laboratory capabilities, the opportunity to perform life science research in space has increased dramatically, while the operational considerations associated with transportation of the experiments has changed dramatically. US researchers have allocations on the European Automated Transfer Vehicle (ATV) and Japanese H-II Transfer Vehicle (HTV). In addition, the International Space Station (ISS) Cargo Resupply Services (CRS) contract will provide consumables and payloads to and from the ISS via the unmanned SpaceX (offers launch and return capabilities) and Orbital (offers only launch capabilities) resupply vehicles. Early requirements drove the capabilities of the vehicle providers; however, many other engineering considerations affect the actual design and operations plans. To better enable the use of the International Space Station as a National Laboratory, ground and on-orbit facility development can augment the vehicle capabilities to better support needs for cell biology, animal research, and conditioned sample return. NASA Life scientists with experience launching research on the space shuttle can find the trades between the capabilities of the many different vehicles to be confusing. In this presentation we will summarize vehicle and associated ground processing capabilities as well as key concepts of operations for different types of life sciences research being launched in the cargo vehicles. We will provide the latest status of vehicle capabilities and support hardware and facilities development being made to enable the broadest implementation of life sciences research on the ISS.

  14. Exosomes from Osteosarcoma and normal osteoblast differ in proteomic cargo and immunomodulatory effects on T cells. (United States)

    Troyer, Ryan M; Ruby, Carl E; Goodall, Cheri P; Yang, Liping; Maier, Claudia S; Albarqi, Hassan A; Brady, Jacqueline V; Bathke, Kallan; Taratula, Oleh; Mourich, Dan; Bracha, Shay


    Canine osteosarcoma (OSA) is the most common cancer of the appendicular skeleton and is associated with high metastatic rate to the lungs and poor prognosis. Recent studies have shown the impact of malignant-derived exosomes on immune cells and the facilitation of immune evasion. In the current study, we have characterized the proteomic profile of exosomes derived from healthy osteoblasts and osteosarcoma cell lines. We investigated the direct impact of these exosomes on healthy T cells. Proteomic cargo of the malignant exosomes was markedly different from osteoblastic exosomes and contained immunosuppressive proteins including TGF-β, α fetoprotein and heat shock proteins. OSA exosomes directly attenuated the rate of T cell proliferation, increased a regulatory (FoxP3+) CD4+ phenotype and diminished the expression of the activation marker CD25+ on CD8+ cells. Exosomes of osteoblasts also demonstrated a direct impact on T cells, but to a lesser degree. Osteosarcoma-derived exosomes compared to normal osteoblasts contain an immunomodulatory cargo, which reduced the rate of T cell proliferation and promoted T regulatory phenotype. Osteoblast-derived exosomes can also reduce T cell activity, but to lesser degree compared to OSA exosomes and without promoting a T regulatory phenotype. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Electric-Field Guided Precision Manipulation of Catalytic Nanomotors for Cargo Delivery and Powering Nanoelectromechanical Devices. (United States)

    Guo, Jianhe; Gallegos, Jeremie June; Tom, Ashley Robyn; Fan, Donglei


    We report a controllable and precision approach in manipulating catalytic nanomotors by strategically applied electric (E-) fields in three dimensions (3-D). With the high controllability, the catalytic nanomotors have demonstrated versatility in capturing, delivering, and releasing of cargos to designated locations as well as in-situ integration with nanomechanical devices (NEMS) to chemically power the actuation. With combined AC and DC E-fields, catalytic nanomotors can be accurately aligned by the AC E-fields and effectively change their speeds instantly by the DC E-fields. Within the 3-D orthogonal microelectrode sets, the in-plane transport of catalytic nanomotors can be swiftly turned on and off, and these catalytic nanomotors can also move in the vertical direction. The interplaying nanoforces that govern the propulsion and alignment are investigated. The modeling of catalytic nanomotors proposed in previous works has been confirmed quantitatively here. Finally, the prowess of the precision manipulation of catalytic nanomotors by E-fields is demonstrated in two applications: the capture, transport, and release of cargos to pre-patterned microdocks, and the assembly of catalytic nanomotors on NEMS to power the continuous rotation. The concepts and approaches reported in this work could further advance applications of catalytic nanomotors, e.g. for assembling and powering nanomachines, nanorobots, and complex NEMS devices.

  16. Intracellular Transport of Cargo in a Sub-diffusive Environment over an Explicit Cytoskeletal Network (United States)

    Maelfeyt, Bryan; Gopinathan, Ajay

    Intracellular transport occurs in nearly all eukaryotic cells, where materials such as proteins, lipids, carbohydrates, and nucleic acids travel to target locations through phases of passive, diffusion-based transport and active, motor-driven transport along filaments that make up the cell's cytoskeleton.We develop a computational model of the process with explicit cytoskeletal filament networks. In the active transport phase, cargo moves in straight lines along these filaments that are spread throughout the cell. To model the passive transport phase of cargo in the cytoplasm, where anomalous sub-diffusion is thought to take place, we implement a continuous-time random walk. We use this approach to provide a stepping stone to a predictive model where we can determine transport properties over a cytoskeletal network provided by experimental images of real filaments. We illustrate our approach by modeling the transport of insulin out of the cell and determining the impact of network geometry, anomalous sub-diffusion and motor number on the first-passage time distributions for insulin granules reaching their target destinations on the membrane.

  17. Crystallization of Saccharomyces cerevisiae aminopeptidase 1, the major cargo protein of the Cvt pathway

    Energy Technology Data Exchange (ETDEWEB)

    Adachi, Wakana; Suzuki, Nobuo N.; Fujioka, Yuko [Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, N-12, W-6, Kita-ku, Sapporo 060-0812 (Japan); Suzuki, Kuninori; Ohsumi, Yoshinori [Division of Molecular Cell Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki 444-8585 (Japan); Inagaki, Fuyuhiko, E-mail: [Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, N-12, W-6, Kita-ku, Sapporo 060-0812 (Japan)


    Aminopeptidase 1, a cargo protein in the cytosol-to-vacuole targeting (Cvt) pathway, was expressed, purified and crystallized in two crystal forms. The vacuole hydrolase aminopeptidase 1 (Ape1) is a cargo protein transported to the vacuole by the cytosol-to-vacuole targeting (Cvt) pathway during conditions of growth and by autophagy during conditions of starvation. After transport to the vacuole, Ape1 is processed into mature Ape1 (mApe1). mApe1 has been expressed, purified and crystallized in two crystal forms. Form I belongs to space group P2{sub 1}, with unit-cell parameters a = 120.6, b = 219.5, c = 133.1 Å, β = 116.5°. Form II belongs to space group R3, with unit-cell parameters a = 141.2, c = 349.4 Å. Diffraction data were collected from these crystals to a resolution of 2.5 Å for form I and 1.83 Å for form II. Self-rotation functions and the volume-to-weight ratio values suggest that forms I and II contain 12 and four mApe1 molecules per asymmetric unit, respectively, and that mApe1 exists as a tetrahedral dodecamer in both crystal forms.

  18. Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites. (United States)

    Lång, Anna; Eriksson, Jens; Schink, Kay Oliver; Lång, Emma; Blicher, Pernille; Połeć, Anna; Brech, Andreas; Dalhus, Bjørn; Bøe, Stig Ove


    Selective nuclear import in eukaryotic cells involves sequential interactions between nuclear import receptors and phenylalanine-glycine (FG)-repeat nucleoporins. Traditionally, binding of cargoes to import receptors is perceived as a nuclear pore complex independent event, while interactions between import complexes and nucleoporins are thought to take place at the nuclear pores. However, studies have shown that nucleoporins are mobile and not static within the nuclear pores, suggesting that they may become engaged in nuclear import before nuclear pore entry. Here we have studied post-mitotic nuclear import of the tumor suppressor protein PML. Since this protein forms nuclear compartments called PML bodies that persist during mitosis, the assembly of putative PML import complexes can be visualized on the surface of these protein aggregates as the cell progress from an import inactive state in mitosis to an import active state in G1. We show that these post-mitotic cytoplasmic PML bodies incorporate a multitude of peripheral nucleoporins, but not scaffold or nuclear basket nucleoporins, in a manner that depends on FG-repeats, the KPNB1 import receptor, and the PML nuclear localization signal. The study suggests that nucleoporins have the ability to target certain nuclear cargo proteins in a nuclear pore-uncoupled state, before nuclear pore entry.

  19. Estimating bulk density of compacted grains in storage bins and modifications of Janssen's load equations as affected by bulk density. (United States)

    Haque, Ekramul


    Janssen created a classical theory based on calculus to estimate static vertical and horizontal pressures within beds of bulk corn. Even today, his equations are widely used to calculate static loadings imposed by granular materials stored in bins. Many standards such as American Concrete Institute (ACI) 313, American Society of Agricultural and Biological Engineers EP 433, German DIN 1055, Canadian Farm Building Code (CFBC), European Code (ENV 1991-4), and Australian Code AS 3774 incorporated Janssen's equations as the standards for static load calculations on bins. One of the main drawbacks of Janssen's equations is the assumption that the bulk density of the stored product remains constant throughout the entire bin. While for all practical purposes, this is true for small bins; in modern commercial-size bins, bulk density of grains substantially increases due to compressive and hoop stresses. Over pressure factors are applied to Janssen loadings to satisfy practical situations such as dynamic loads due to bin filling and emptying, but there are limited theoretical methods available that include the effects of increased bulk density on the loadings of grain transmitted to the storage structures. This article develops a mathematical equation relating the specific weight as a function of location and other variables of materials and storage. It was found that the bulk density of stored granular materials increased with the depth according to a mathematical equation relating the two variables, and applying this bulk-density function, Janssen's equations for vertical and horizontal pressures were modified as presented in this article. The validity of this specific weight function was tested by using the principles of mathematics. As expected, calculations of loads based on the modified equations were consistently higher than the Janssen loadings based on noncompacted bulk densities for all grain depths and types accounting for the effects of increased bulk densities

  20. La confiabilidad en los sistemas eléctricos competitivos y el modelo colombiano de cargo por confiabilidad

    Directory of Open Access Journals (Sweden)

    Vélez Luis Guillermo


    Full Text Available El propósito de este artículo es hacer un análisis de la seguridad en el suministro de electricidad en Colombia, considerando el nuevo esquema del Cargo por Confiabilidad, modelo adoptado en Colombia para garantizar las inversiones en generación. Para esto se analiza la diferencia entre escenarios de demanda y de oferta de electricidad. La oferta para las plantas nuevas considera las OEF adquiridas con el cargo; y para las plantas existentes se realizan simulaciones bajo diversos escenarios de ocurrencia del fenómeno de “El Niño”. La demanda fue tomada de las proyecciones de la UPME. Las simulaciones realizadas muestran una apropiada dimensión del tamaño del Cargo por Confiabilidad.