WorldWideScience

Sample records for building highly sensitive

  1. Building high-efficiency CdS/CdSe-sensitized solar cells with a hierarchically branched double-layer architecture.

    Science.gov (United States)

    Zhu, Zonglong; Qiu, Jianhang; Yan, Keyou; Yang, Shihe

    2013-05-22

    We report a double-layer architecture for a photoanode of quantum-dot-sensitized solar cells (QDSSCs), which consists of a ZnO nanorod array (NR) underlayer and a ZnO nanotetrapod (TP) top layer. Such double-layer and branching strategies have significantly increased the power conversion efficiency (PCE) to as high as 5.24%, nearly reaching the record PCE of QDSSCs based on TiO2. Our systematic studies have shown that the double-layer strategy could significantly reduce charge recombination at the interface between the charge collection anode (FTO) and ZnO nanostructure because of the strong and compact adhesion of the NRs and enhance charge transport due to the partially interpenetrating contact between the NR and TP layers, leading to improved open-circuit voltage (Voc) and short-circuit current density (Jsc). Also, when the double layer was subjected to further branching, a large increase in Jsc and, to a lesser extent, the fill factor (FF) has resulted from increases in quantum-dot loading, enhanced light scattering, and reduced series resistance.

  2. Constructing high-efficiency D-A-π-A-featured solar cell sensitizers: a promising building block of 2,3-diphenylquinoxaline for antiaggregation and photostability.

    Science.gov (United States)

    Pei, Kai; Wu, Yongzhen; Islam, Ashraful; Zhang, Qiong; Han, Liyuan; Tian, He; Zhu, Weihong

    2013-06-12

    Controlling the sensitizer morphology on a nanocrystalline TiO2 surface is beneficial to facilitating electron injection and suppressing charge recombination. Given that the grafted alkyl chain on a π-bridge thiophene segment for preventing π aggregation can deteriorate its intrinsic photostability, we incorporate a promising building block of 2,3-diphenylquinoxaline as the additional acceptor to construct a novel D-A-π-A-featured dye IQ4, which exhibits several characteristics: (i) efficiently decreasing the molecular HOMO-LUMO energy gap by extending its absorption bands; (ii) showing a moderate electron-withdrawing capability for an ideal balance in both promising photocurrent and photovoltage; (iii) endowing an ideal morphology control with strong capability of restraining the intermolecular aggregation and facilitating the formation of a compact sensitizer layer via two twisted phenyl groups grafted onto the quinoxaline unit. The coadsorbent-free dye-sensitized solar cell (DSSC) based on dye IQ4 exhibits very promising conversion efficiency as high as 9.24 ± 0.05%, with a short-circuit current density (Jsc) of 17.55 mA cm(-2), an open-circuit voltage (Voc) of 0.74 V, and a fill factor (FF) of 0.71 under AM 1.5 illumination (100 mW cm(-2)). IQ4-based DSSC devices with an ionic liquid electrolyte can keep constant performance during a 1000 h aging test under 1 sun at 60 °C. Because of spatial restriction, the two phenyl groups grafted onto the additional electron-withdrawing quinoxaline are demonstrated as efficient building blocks, not only improving its photostability and thermal stability but also allowing it to be a successful antiaggregation functional unit. As a consequence, the incorporated 2,3-diphenylquinoxaline unit can realize a facile structural modification for constructing organic coadsorbent-free D-A-π-A-featured sensitizers, thus paving a way to replace the common, stability-deleterious grafted alkyl chain on the thienyl bridge.

  3. Interactive Building Design Space Exploration Using Regionalized Sensitivity Analysis

    DEFF Research Database (Denmark)

    Jensen, Rasmus Lund; Maagaard, Steffen; Østergård, Torben

    2017-01-01

    Monte Carlo simulations combined with regionalized sensitivity analysis provide the means to explore a vast, multivariate design space in building design. Typically, sensitivity analysis shows how the variability of model output relates to the uncertainties in models inputs. This reveals which...... in combination with the interactive parallel coordinate plot (PCP). The latter is an effective tool to explore stochastic simulations and to find high-performing building designs. The proposed methods help decision makers to focus their attention to the most important design parameters when exploring...... a multivariate design space. As case study, we consider building performance simulations of a 15.000 m² educational centre with respect to energy demand, thermal comfort, and daylight....

  4. High-Sensitivity Spectrophotometry.

    Science.gov (United States)

    Harris, T. D.

    1982-01-01

    Selected high-sensitivity spectrophotometric methods are examined, and comparisons are made of their relative strengths and weaknesses and the circumstances for which each can best be applied. Methods include long path cells, noise reduction, laser intracavity absorption, thermocouple calorimetry, photoacoustic methods, and thermo-optical methods.…

  5. INL High Performance Building Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Jennifer D. Morton

    2010-02-01

    High performance buildings, also known as sustainable buildings and green buildings, are resource efficient structures that minimize the impact on the environment by using less energy and water, reduce solid waste and pollutants, and limit the depletion of natural resources while also providing a thermally and visually comfortable working environment that increases productivity for building occupants. As Idaho National Laboratory (INL) becomes the nation’s premier nuclear energy research laboratory, the physical infrastructure will be established to help accomplish this mission. This infrastructure, particularly the buildings, should incorporate high performance sustainable design features in order to be environmentally responsible and reflect an image of progressiveness and innovation to the public and prospective employees. Additionally, INL is a large consumer of energy that contributes to both carbon emissions and resource inefficiency. In the current climate of rising energy prices and political pressure for carbon reduction, this guide will help new construction project teams to design facilities that are sustainable and reduce energy costs, thereby reducing carbon emissions. With these concerns in mind, the recommendations described in the INL High Performance Building Strategy (previously called the INL Green Building Strategy) are intended to form the INL foundation for high performance building standards. This revised strategy incorporates the latest federal and DOE orders (Executive Order [EO] 13514, “Federal Leadership in Environmental, Energy, and Economic Performance” [2009], EO 13423, “Strengthening Federal Environmental, Energy, and Transportation Management” [2007], and DOE Order 430.2B, “Departmental Energy, Renewable Energy, and Transportation Management” [2008]), the latest guidelines, trends, and observations in high performance building construction, and the latest changes to the Leadership in Energy and Environmental Design

  6. Highly Sensitive Optical Receivers

    CERN Document Server

    Schneider, Kerstin

    2006-01-01

    Highly Sensitive Optical Receivers primarily treats the circuit design of optical receivers with external photodiodes. Continuous-mode and burst-mode receivers are compared. The monograph first summarizes the basics of III/V photodetectors, transistor and noise models, bit-error rate, sensitivity and analog circuit design, thus enabling readers to understand the circuits described in the main part of the book. In order to cover the topic comprehensively, detailed descriptions of receivers for optical data communication in general and, in particular, optical burst-mode receivers in deep-sub-µm CMOS are presented. Numerous detailed and elaborate illustrations facilitate better understanding.

  7. Application of Sensitivity Analysis in Design of Sustainable Buildings

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik; Rasmussen, Henrik

    2009-01-01

    satisfies the design objectives and criteria. In the design of sustainable buildings, it is beneficial to identify the most important design parameters in order to more efficiently develop alternative design solutions or reach optimized design solutions. Sensitivity analyses make it possible to identify...... the most important parameters in relation to building performance and to focus design and optimization of sustainable buildings on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage of the building design process, where it is still...

  8. Application of Sensitivity Analysis in Design of Sustainable Buildings

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik; Hesselholt, Allan Tind

    2007-01-01

    satisfies the design requirements and objectives. In the design of sustainable Buildings it is beneficial to identify the most important design parameters in order to develop more efficiently alternative design solutions or reach optimized design solutions. A sensitivity analysis makes it possible...... to identify the most important parameters in relation to building performance and to focus design and optimization of sustainable buildings on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage of the building design process, where...

  9. Sensitivity Analysis Applied in Design of Low Energy Office Building

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik

    2008-01-01

    Building performance can be expressed by different indicators as primary energy use, environmental load and/or the indoor environmental quality and a building performance simulation can provide the decision maker with a quantitative measure of the extent to which an integrated design solution...... satisfies the design requirements and objectives. In the design of sustainable Buildings it is beneficial to identify the most important design parameters in order to develop more efficiently alternative design solutions or reach optimized design solutions. A sensitivity analysis makes it possible...... to identify the most important parameters in relation to building performance and to focus design and optimization of sustainable buildings on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage of the building design process, where...

  10. High-Sensitivity Magnetization Measurements

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The three most common instruments for high-sensitivity magnetization measurements (the vibrating-sample magnetometer, the alternating gradient magnetometer, and the SQUID magne tometer) are described and their limiting sensitivities are discussed. The advantages and disad vantages of each are described. Magnetometers using micro-machined force detectors are briefly mentioned.

  11. Project materials [Commercial High Performance Buildings Project

    Energy Technology Data Exchange (ETDEWEB)

    None

    2001-01-01

    The Consortium for High Performance Buildings (ChiPB) is an outgrowth of DOE'S Commercial Whole Buildings Roadmapping initiatives. It is a team-driven public/private partnership that seeks to enable and demonstrate the benefit of buildings that are designed, built and operated to be energy efficient, environmentally sustainable, superior quality, and cost effective.

  12. 77 FR 2296 - Office of Federal High-Performance Green Buildings; the Green Building Advisory Committee...

    Science.gov (United States)

    2012-01-17

    ... ADMINISTRATION Office of Federal High-Performance Green Buildings; the Green Building Advisory Committee... provides the schedule for three teleconference meetings of the Green Building Advisory Committee (the..., Designated Federal Officer, Office of Federal High Performance Green Buildings, Office of...

  13. See-through dye-sensitized solar cells: photonic reflectors for tandem and building integrated photovoltaics.

    Science.gov (United States)

    Heiniger, Leo-Philipp; O'Brien, Paul G; Soheilnia, Navid; Yang, Yang; Kherani, Nazir P; Grätzel, Michael; Ozin, Geoffrey A; Tétreault, Nicolas

    2013-10-25

    See-through dye-sensitized solar cells with 1D photonic crystal Bragg reflector photoanodes show an increase in peak external quantum efficiency of 47% while still maintaining high fill factors, resulting in an almost 40% increase in power conversion efficiency. These photoanodes are ideally suited for tandem and building integrated photovoltaics.

  14. EULEB EUropean high quality Low Energy Buildings

    OpenAIRE

    2006-01-01

    ABSTRACT: The EULEB-Project is intended to supply information to architects and engineers throughout Europe and beyond it. Within the EU it will support the new Energy Directive on Buildings through providing design and engineering details of European public high quality buildings with low energy consumption. By providing a CD containing information on architecture, energy consumption and economical efficiency as well as the comfort of these innovative buildings in use, the lac...

  15. Building Trust in High-Performing Teams

    Directory of Open Access Journals (Sweden)

    Aki Soudunsaari

    2012-06-01

    Full Text Available Facilitation of growth is more about good, trustworthy contacts than capital. Trust is a driving force for business creation, and to create a global business you need to build a team that is capable of meeting the challenge. Trust is a key factor in team building and a needed enabler for cooperation. In general, trust building is a slow process, but it can be accelerated with open interaction and good communication skills. The fast-growing and ever-changing nature of global business sets demands for cooperation and team building, especially for startup companies. Trust building needs personal knowledge and regular face-to-face interaction, but it also requires empathy, respect, and genuine listening. Trust increases communication, and rich and open communication is essential for the building of high-performing teams. Other building materials are a shared vision, clear roles and responsibilities, willingness for cooperation, and supporting and encouraging leadership. This study focuses on trust in high-performing teams. It asks whether it is possible to manage trust and which tools and operation models should be used to speed up the building of trust. In this article, preliminary results from the authors’ research are presented to highlight the importance of sharing critical information and having a high level of communication through constant interaction.

  16. Building Highly Flexible Polyelectrolyte Nanotubes

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Flexibility of polyelectrolyte nanotubes is necessary if they are to be exploited in applications such as developing photoelectric devices with strong mechanical properties. In a recent attempt, high flexibility has been observed from such nanotubes prepared by a research team headed by Prof. Li Junbai of the CAS Institute of Chemistry (ICCAS).

  17. High-performance commercial building systems

    Energy Technology Data Exchange (ETDEWEB)

    Selkowitz, Stephen

    2003-10-01

    This report summarizes key technical accomplishments resulting from the three year PIER-funded R&D program, ''High Performance Commercial Building Systems'' (HPCBS). The program targets the commercial building sector in California, an end-use sector that accounts for about one-third of all California electricity consumption and an even larger fraction of peak demand, at a cost of over $10B/year. Commercial buildings also have a major impact on occupant health, comfort and productivity. Building design and operations practices that influence energy use are deeply engrained in a fragmented, risk-averse industry that is slow to change. Although California's aggressive standards efforts have resulted in new buildings designed to use less energy than those constructed 20 years ago, the actual savings realized are still well below technical and economic potentials. The broad goal of this program is to develop and deploy a set of energy-saving technologies, strategies, and techniques, and improve processes for designing, commissioning, and operating commercial buildings, while improving health, comfort, and performance of occupants, all in a manner consistent with sound economic investment practices. Results are to be broadly applicable to the commercial sector for different building sizes and types, e.g. offices and schools, for different classes of ownership, both public and private, and for owner-occupied as well as speculative buildings. The program aims to facilitate significant electricity use savings in the California commercial sector by 2015, while assuring that these savings are affordable and promote high quality indoor environments. The five linked technical program elements contain 14 projects with 41 distinct R&D tasks. Collectively they form a comprehensive Research, Development, and Demonstration (RD&D) program with the potential to capture large savings in the commercial building sector, providing significant economic benefits to

  18. Hybrid ventilation systems and high performance buildings

    Energy Technology Data Exchange (ETDEWEB)

    Utzinger, D.M. [Wisconsin Univ., Milwaukee, WI (United States). School of Architecture and Urban Planning

    2009-07-01

    This paper described hybrid ventilation design strategies and their impact on 3 high performance buildings located in southern Wisconsin. The Hybrid ventilation systems combined occupant controlled natural ventilation with mechanical ventilation systems. Natural ventilation was shown to provide adequate ventilation when appropriately designed. Proper control integration of natural ventilation into hybrid systems was shown to reduce energy consumption in high performance buildings. This paper also described the lessons learned from the 3 buildings. The author served as energy consultant on all three projects and had the responsibility of designing and integrating the natural ventilation systems into the HVAC control strategy. A post occupancy evaluation of building energy performance has provided learning material for architecture students. The 3 buildings included the Schlitz Audubon Nature Center completed in 2003; the Urban Ecology Center completed in 2004; and the Aldo Leopold Legacy Center completed in 2007. This paper included the size, measured energy utilization intensity and percentage of energy supplied by renewable solar power and bio-fuels on site for each building. 6 refs., 2 tabs., 6 figs.

  19. See-Through Dye-Sensitized Solar Cells: Photonic Reflectors for Tandem and Building Integrated Photovoltaics

    KAUST Repository

    Heiniger, Leo-Philipp

    2013-08-21

    See-through dye-sensitized solar cells with 1D photonic crystal Bragg reflector photoanodes show an increase in peak external quantum efficiency of 47% while still maintaining high fill factors, resulting in an almost 40% increase in power conversion efficiency. These photoanodes are ideally suited for tandem and building integrated photovoltaics. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. FIRE EVACUATION FROM HIGH-RISE BUILDINGS

    Directory of Open Access Journals (Sweden)

    Korol'chenko Aleksandr Yakovlevich

    2012-10-01

    Full Text Available The authors argue that no collapse of structures is likely in the event of a fire emergency in multistoried buildings, rather, other fire-related factors may endanger the lives of people inside high-rise buildings exposed to the fire emergency, including open fire, sparks, high ambient temperature, smoke and toxic combustion products, reduced concentration of oxygen, and combined influence of various factors. In case of fire, the temperature inside buildings reaches 1100 °С. It exceeds the temperature of the ambient air acceptable for humans by far (70 °С. The experiments demonstrate that combustion products contain hundreds of toxic chemical compounds. The most hazardous of them include carbon oxide, carbon dioxide, chloride and cyanic hydrogen, aldehydes and acrolein. The author provides the pattern of their influence on the human body. The smoke consists of unburned particles of carbon and aerosols. The size of particles fluctuates within 0.05-50 MMK. Smoke produces a physiological and psychological impact on human beings. It has been proven that dangerous fire factors emerge within the first five to ten minutes of the emergency situation. Evacuation is the principal method of safety assurance. However, the velocity of propagation of smoke and heat is so high that even if the fire prevention system is in operation, people may be blocked both on the floors that are exposed to the fire and those that escape its propagation. New evacuation and rescue methods are recommended by the author. Various ways and methods of use of life-saving facilities are also provided. Safe evacuation is feasible from buildings where the number of stories does not exceed 10- 12. During evacuation, high density human streams are formed inside buildings, therefore, the period of stay in a burning building is increased. The calculations have proven that a two-minute delay of evacuation converts into a safe evacuation of only 13-15% of people. Low reliability of

  1. Intelligent Facades for High Performance Green Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Dyson, Anna [Rensselaer Polytechnic Inst., Troy, NY (United States)

    2017-03-01

    Progress Towards Net-Zero and Net-Positive-Energy Commercial Buildings and Urban Districts Through Intelligent Building Envelope Strategies Previous research and development of intelligent facades systems has been limited in their contribution towards national goals for achieving on-site net zero buildings, because this R&D has failed to couple the many qualitative requirements of building envelopes such as the provision of daylighting, access to exterior views, satisfying aesthetic and cultural characteristics, with the quantitative metrics of energy harvesting, storage and redistribution. To achieve energy self-sufficiency from on-site solar resources, building envelopes can and must address this gamut of concerns simultaneously. With this project, we have undertaken a high-performance building integrated combined-heat and power concentrating photovoltaic system with high temperature thermal capture, storage and transport towards multiple applications (BICPV/T). The critical contribution we are offering with the Integrated Concentrating Solar Façade (ICSF) is conceived to improve daylighting quality for improved health of occupants and mitigate solar heat gain while maximally capturing and transferring onsite solar energy. The ICSF accomplishes this multi-functionality by intercepting only the direct-normal component of solar energy (which is responsible for elevated cooling loads) thereby transforming a previously problematic source of energy into a high quality resource that can be applied to building demands such as heating, cooling, dehumidification, domestic hot water, and possible further augmentation of electrical generation through organic Rankine cycles. With the ICSF technology, our team is addressing the global challenge in transitioning commercial and residential building stock towards on-site clean energy self-sufficiency, by fully integrating innovative environmental control systems strategies within an intelligent and responsively dynamic building

  2. Commercial Buildings High Performance Rooftop Unit Challenge

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-16

    The U.S. Department of Energy (DOE) and the Commercial Building Energy Alliances (CBEAs) are releasing a new design specification for high performance rooftop air conditioning units (RTUs). Manufacturers who develop RTUs based on this new specification will find strong interest from the commercial sector due to the energy and financial savings.

  3. Integrating advanced facades into high performance buildings

    Energy Technology Data Exchange (ETDEWEB)

    Selkowitz, Stephen E.

    2001-05-01

    Glass is a remarkable material but its functionality is significantly enhanced when it is processed or altered to provide added intrinsic capabilities. The overall performance of glass elements in a building can be further enhanced when they are designed to be part of a complete facade system. Finally the facade system delivers the greatest performance to the building owner and occupants when it becomes an essential element of a fully integrated building design. This presentation examines the growing interest in incorporating advanced glazing elements into more comprehensive facade and building systems in a manner that increases comfort, productivity and amenity for occupants, reduces operating costs for building owners, and contributes to improving the health of the planet by reducing overall energy use and negative environmental impacts. We explore the role of glazing systems in dynamic and responsive facades that provide the following functionality: Enhanced sun protection and cooling load control while improving thermal comfort and providing most of the light needed with daylighting; Enhanced air quality and reduced cooling loads using natural ventilation schemes employing the facade as an active air control element; Reduced operating costs by minimizing lighting, cooling and heating energy use by optimizing the daylighting-thermal tradeoffs; Net positive contributions to the energy balance of the building using integrated photovoltaic systems; Improved indoor environments leading to enhanced occupant health, comfort and performance. In addressing these issues facade system solutions must, of course, respect the constraints of latitude, location, solar orientation, acoustics, earthquake and fire safety, etc. Since climate and occupant needs are dynamic variables, in a high performance building the facade solution have the capacity to respond and adapt to these variable exterior conditions and to changing occupant needs. This responsive performance capability

  4. High sensitivity RNA pseudoknot prediction

    OpenAIRE

    Huang, Xiaolu; Ali, Hesham

    2006-01-01

    Most ab initio pseudoknot predicting methods provide very few folding scenarios for a given RNA sequence and have low sensitivities. RNA researchers, in many cases, would rather sacrifice the specificity for a much higher sensitivity for pseudoknot detection. In this study, we introduce the Pseudoknot Local Motif Model and Dynamic Partner Sequence Stacking (PLMM_DPSS) algorithm which predicts all PLM model pseudoknots within an RNA sequence in a neighboring-region-interference-free fashion. T...

  5. High sensitivity RNA pseudoknot prediction.

    Science.gov (United States)

    Huang, Xiaolu; Ali, Hesham

    2007-01-01

    Most ab initio pseudoknot predicting methods provide very few folding scenarios for a given RNA sequence and have low sensitivities. RNA researchers, in many cases, would rather sacrifice the specificity for a much higher sensitivity for pseudoknot detection. In this study, we introduce the Pseudoknot Local Motif Model and Dynamic Partner Sequence Stacking (PLMM_DPSS) algorithm which predicts all PLM model pseudoknots within an RNA sequence in a neighboring-region-interference-free fashion. The PLM model is derived from the existing Pseudobase entries. The innovative DPSS approach calculates the optimally lowest stacking energy between two partner sequences. Combined with the Mfold, PLMM_DPSS can also be used in predicting complicated pseudoknots. The test results of PLMM_DPSS, PKNOTS, iterated loop matching, pknotsRG and HotKnots with Pseudobase sequences have shown that PLMM_DPSS is the most sensitive among the five methods. PLMM_DPSS also provides manageable pseudoknot folding scenarios for further structure determination.

  6. 77 FR 66616 - Office of Federal High-Performance Green Buildings; Green Building Advisory Committee...

    Science.gov (United States)

    2012-11-06

    ... ADMINISTRATION Office of Federal High-Performance Green Buildings; Green Building Advisory Committee... provides the schedule and agenda for the November 27, 2012, meeting of the Green Building Advisory... High-Performance Green Buildings, Office of Government-wide Policy, General Services...

  7. 77 FR 24494 - Office of Federal High-Performance Green Buildings; Green Building Advisory Committee...

    Science.gov (United States)

    2012-04-24

    ... ADMINISTRATION Office of Federal High-Performance Green Buildings; Green Building Advisory Committee... and agenda for the May 9, 2012, meeting of the Green Building Advisory Committee Meeting (the... Sandler, Designated Federal Officer, Office of Federal High-Performance Green Buildings, Office...

  8. High-performance commercial building systems

    Energy Technology Data Exchange (ETDEWEB)

    Selkowitz, Stephen

    2003-10-01

    This report summarizes key technical accomplishments resulting from the three year PIER-funded R&D program, ''High Performance Commercial Building Systems'' (HPCBS). The program targets the commercial building sector in California, an end-use sector that accounts for about one-third of all California electricity consumption and an even larger fraction of peak demand, at a cost of over $10B/year. Commercial buildings also have a major impact on occupant health, comfort and productivity. Building design and operations practices that influence energy use are deeply engrained in a fragmented, risk-averse industry that is slow to change. Although California's aggressive standards efforts have resulted in new buildings designed to use less energy than those constructed 20 years ago, the actual savings realized are still well below technical and economic potentials. The broad goal of this program is to develop and deploy a set of energy-saving technologies, strategies, and techniques, and improve processes for designing, commissioning, and operating commercial buildings, while improving health, comfort, and performance of occupants, all in a manner consistent with sound economic investment practices. Results are to be broadly applicable to the commercial sector for different building sizes and types, e.g. offices and schools, for different classes of ownership, both public and private, and for owner-occupied as well as speculative buildings. The program aims to facilitate significant electricity use savings in the California commercial sector by 2015, while assuring that these savings are affordable and promote high quality indoor environments. The five linked technical program elements contain 14 projects with 41 distinct R&D tasks. Collectively they form a comprehensive Research, Development, and Demonstration (RD&D) program with the potential to capture large savings in the commercial building sector, providing significant economic benefits to

  9. High-tech buildings - Market transformation project

    Energy Technology Data Exchange (ETDEWEB)

    Applications Team

    2001-10-01

    Facility managers and designers know their buildings are energy intensive yet have few techniques to quantify cleanroom energy performance. Benchmarking identifies the energy end uses in a cleanroom. As expected, besides the process loads, which are often very intense, the mechanical systems are the most energy intensive in these buildings. Benchmarking the mechanical systems and components can provide useful information on system and component performance and provide a basis to identify energy-saving opportunities in cleanrooms. HVAC systems in cleanrooms are dramatically different from their counterparts in commercial buildings in terms of reliability, safety requirements, and scale. The design of cleanroom HVAC systems is a specialty area requiring unique understanding of cleanliness guidelines, airflow quantities, room pressurization, code requirements, specialty equipment, tight control, and many more details. The HVAC systems must also operate reliably and safely. Since recirculation air systems use large amounts of fan power in moving large amounts of conditioned air through HEPA filters, the cleanroom, and return pathways they represent one of the largest energy end uses in a cleanroom. In addition, many processes requiring cleanrooms also have large make-up and exhaust airflow needs requiring huge amounts of energy to move and condition the displaced air. Energy intensity for mechanical systems in cleanrooms ranges between 4 to 100 times that of commercial buildings. There is, however, a lack of comparative data on the performance of cleanroom mechanical systems. To better understand existing cleanroom systems in high technology industries, and to better enable building owners, operators, and designers to compare energy use for a given cleanroom to others, it is necessary to benchmark energy performance in such facilities.

  10. High sensitivity radon emanation measurements.

    Science.gov (United States)

    Zuzel, G; Simgen, H

    2009-05-01

    The presented radon detection technique employs miniaturized ultra-low background proportional counters. (222)Rn samples are purified, mixed with a counting gas and filled into a counter using a special glass vacuum line. The absolute sensitivity of the system is estimated to be 40 microBq (20 (222)Rn atoms). For emanation investigations two metal sealed stainless steel vessels and several glass vials are available. Taking into account their blank contributions, measurements at a minimum detectable activity of about 100 microBq can be performed.

  11. 78 FR 21368 - Office of Federal High-Performance Green Buildings; Green Building Advisory Committee...

    Science.gov (United States)

    2013-04-10

    ... ADMINISTRATION Office of Federal High-Performance Green Buildings; Green Building Advisory Committee... provides the schedule and agenda for the May 1, 2013, meeting of the Green Building Advisory Committee... Green Buildings, Office of Government-wide Policy, General Services Administration, 1275 First Street...

  12. Cryogenic High-Sensitivity Magnetometer

    Science.gov (United States)

    Day, Peter; Chui, Talso; Goodstein, David

    2005-01-01

    A proposed magnetometer for use in a cryogenic environment would be sensitive enough to measure a magnetic-flux density as small as a picogauss (10(exp -16) Tesla). In contrast, a typical conventional flux-gate magnetometer cannot measure a magnetic-flux density smaller that about 1 microgauss (10(exp -10) Tesla). One version of this device, for operation near the low end of the cryogenic temperature range, would include a piece of a paramagnetic material on a platform, the temperature of which would be controlled with a periodic variation. The variation in temperature would be measured by use of a conventional germanium resistance thermometer. A superconducting coil would be wound around the paramagnetic material and coupled to a superconducting quantum interference device (SQUID) magnetometer.

  13. Nano-textured high sensitivity ion sensitive field effect transistors

    Energy Technology Data Exchange (ETDEWEB)

    Hajmirzaheydarali, M.; Sadeghipari, M.; Akbari, M.; Shahsafi, A.; Mohajerzadeh, S., E-mail: mohajer@ut.ac.ir [Thin Film and Nanoelectronics Lab, Nanoelectronics Center of Excellence, School of Electrical and Computer Engineering, University of Tehran, Tehran 143957131 (Iran, Islamic Republic of)

    2016-02-07

    Nano-textured gate engineered ion sensitive field effect transistors (ISFETs), suitable for high sensitivity pH sensors, have been realized. Utilizing a mask-less deep reactive ion etching results in ultra-fine poly-Si features on the gate of ISFET devices where spacing of the order of 10 nm and less is achieved. Incorporation of these nano-sized features on the gate is responsible for high sensitivities up to 400 mV/pH in contrast to conventional planar structures. The fabrication process for this transistor is inexpensive, and it is fully compatible with standard complementary metal oxide semiconductor fabrication procedure. A theoretical modeling has also been presented to predict the extension of the diffuse layer into the electrolyte solution for highly featured structures and to correlate this extension with the high sensitivity of the device. The observed ultra-fine features by means of scanning electron microscopy and transmission electron microscopy tools corroborate the theoretical prediction.

  14. Thermal comfort in residential buildings: Sensitivity to building parameters and occupancy

    NARCIS (Netherlands)

    Ioannou, A.; Itard, L.C.M.

    2014-01-01

    Dynamic simulation is widely used for assessing thermal comfort in dwellings. Simulation tools, though, have shortcomings due to false assumptions made during the design phase of buildings, limited information on the building's envelope and installations and misunderstandings over the role of the oc

  15. 78 FR 56703 - Office of Federal High-Performance Green Buildings; Green Building Advisory Committee...

    Science.gov (United States)

    2013-09-13

    ... ADMINISTRATION Office of Federal High-Performance Green Buildings; Green Building Advisory Committee..., 2013, meeting of the Green Building Advisory Committee Meeting (the Committee) and the schedule for a... CONTACT: Ken Sandler, Designated Federal Officer, ] Office of Federal High-Performance Green...

  16. Application of Sensitivity Analysis in Design of Integrated Building Concepts

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik; Hesselholt, Allan Tind

    2007-01-01

    Building performance can be expressed by different indicators as primary energy use, environmental load and/or the indoor environmental quality and a building performance simulation can provide the decision maker with a quantitative measure of the extent to which a design solution satisfies...... the design requirements and objectives. In the design of integrated building concepts it is beneficial to identify the most important design parameters in order to more efficiently develop alternative design solutions or more efficiently perform an optimization of the building performance. The sensitivity...... analysis makes it possible to identify the most important parameters in relation to building performance and to focus design and optimization of integrated building concepts on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage...

  17. AUTOMATIC EXTRACTION OF BUILDING OUTLINE FROM HIGH RESOLUTION AERIAL IMAGERY

    Directory of Open Access Journals (Sweden)

    Y. Wang

    2016-06-01

    Full Text Available In this paper, a new approach for automated extraction of building boundary from high resolution imagery is proposed. The proposed approach uses both geometric and spectral properties of a building to detect and locate buildings accurately. It consists of automatic generation of high quality point cloud from the imagery, building detection from point cloud, classification of building roof and generation of building outline. Point cloud is generated from the imagery automatically using semi-global image matching technology. Buildings are detected from the differential surface generated from the point cloud. Further classification of building roof is performed in order to generate accurate building outline. Finally classified building roof is converted into vector format. Numerous tests have been done on images in different locations and results are presented in the paper.

  18. Automatic Extraction of Building Outline from High Resolution Aerial Imagery

    Science.gov (United States)

    Wang, Yandong

    2016-06-01

    In this paper, a new approach for automated extraction of building boundary from high resolution imagery is proposed. The proposed approach uses both geometric and spectral properties of a building to detect and locate buildings accurately. It consists of automatic generation of high quality point cloud from the imagery, building detection from point cloud, classification of building roof and generation of building outline. Point cloud is generated from the imagery automatically using semi-global image matching technology. Buildings are detected from the differential surface generated from the point cloud. Further classification of building roof is performed in order to generate accurate building outline. Finally classified building roof is converted into vector format. Numerous tests have been done on images in different locations and results are presented in the paper.

  19. A sensitivity model for energy consumption in buildings. Part 1: Effect of exterior environment

    Science.gov (United States)

    Lansing, F. L.

    1981-01-01

    A simple analytical model is developed for the simulation of seasonal heating and cooling loads of any class of buildings to complement available computerized techniques which make hourly, daily, and monthly calculations. An expression for the annual energy utilization index, which is a common measure of rating buildings having the same functional utilization, is derived to include about 30 parameters for both building interior and exterior environments. The sensitivity of a general class building to either controlled or uncontrolled weather parameters is examined. A hypothetical office type building, located at the Goldstone Space Communication Complex, Goldstone, California, is selected as an example for the numerical sensitivity evaluations. Several expressions of variations in local outside air temperature, pressure, solar radiation, and wind velocity are presented.

  20. SENSITIVITY ANALYSIS as a methodical approach to the development of design strategies for environmentally sustainable buildings

    DEFF Research Database (Denmark)

    Hansen, Hanne Tine Ring

    architecture through an integrated design approach. The findings of the literature study and the qualitative interview have directed the PhD project towards the importance of project specific design strategies and an integrated and multiprofessional approach to environmentally sustainable building design....... The project therefore focuses on the issue of design strategy development in an experimental application of sensitivity analysis as a methodical approach to the development of a design strategy for a new energy-efficient residential building in Denmark. The outset of the analysis is a single family reference...... building through which the sensitivity of parameters relating to energy and residential building design are analysed. In conclusion the PhD project discusses the strengths and weaknesses of sensitivity analysis as a methodical approach to design strategy development, and makes a suggestion...

  1. High sensitivity knitted fabric strain sensors

    Science.gov (United States)

    Xie, Juan; Long, Hairu; Miao, Menghe

    2016-10-01

    Wearable sensors are increasingly used in smart garments for detecting and transferring vital signals and body posture, movement and respiration. Existing fabric strain sensors made from metallized yarns have low sensitivity, poor comfort and low durability to washing. Here we report a knitted fabric strain sensor made from a cotton/stainless steel (SS) fibre blended yarn which shows much higher sensitivity than sensors knitted from metallized yarns. The fabric feels softer than pure cotton textiles owing to the ultrafine stainless steel fibres and does not lose its electrical property after washing. The reason for the high sensitivity of the cotton/SS knitted fabric sensor was explored by comparing its sensing mechanism with the knitted fabric sensor made from metallized yarns. The results show that the cotton/SS yarn-to-yarn contact resistance is highly sensitive to strain applied to hooked yarn loops.

  2. High Sensitivity deflection detection of nanowires

    Energy Technology Data Exchange (ETDEWEB)

    Sanii, Babak; Ashby, Paul

    2009-10-28

    A critical limitation of nanoelectromechanical systems (NEMS) is the lack of a high-sensitivity position detection mechanism. We introduce a noninterferometric optical approach to determine the position of nanowires with a high sensitivity and bandwidth. Its physical origins and limitations are determined by Mie scattering analysis. This enables a dramatic miniaturization of detectable cantilevers, with attendant reductions to the fundamental minimum force noise in highly damping environments. We measure the force noise of an 81{+-}9??nm radius Ag{sub 2}Ga nanowire cantilever in water at 6{+-}3??fN/{radical}Hz.

  3. Sensitivity analysis for daily building operation from the energy and thermal comfort standpoint

    Directory of Open Access Journals (Sweden)

    Ignjatović Marko G.

    2016-01-01

    Full Text Available Improving energy performance of buildings is one of the most important tasks for reaching sustainability. Assessing building energy consumption is performed more often with specialized simulation tools. Sensitivity analysis proved to be a valuable tool for creating more reliable and realistic building energy models and better buildings. This paper briefly describes the methodology for running global sensitivity analysis and tools that can be used, and presents the results of such an analysis conducted for winter period, daily, on input variables covering a real building's operation, control and occupant related parameters that affect both thermal comfort and heating energy consumption. Two sets of inputs were created. The only difference between these sets is an addition of clothing insulation and occupant heat gain as input variables. The reference building was simulated for three distinctive winter weeks. Two additional input variables have an effect especially on thermal comfort, but they do not disturb the relative order of other influential input variables. The common influential variables for both energy consumption and thermal comfort were identified and are: air handling unit sup-ply temperature and airflow rate and control system related parameters. This can help in future research into implementing the simulation-assisted optimized operation in real buildings. [Projekat Ministarstva nauke Republike Srbije, br. TR-33051: The concept of sustainable energy supply of settlements with energy efficient buildings

  4. High Performance Building Mockup in FLEXLAB

    Energy Technology Data Exchange (ETDEWEB)

    McNeil, Andrew [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kohler, Christian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lee, Eleanor S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Selkowitz, Stephen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-08-30

    Genentech has ambitious energy and indoor environmental quality performance goals for Building 35 (B35) being constructed by Webcor at the South San Francisco campus. Genentech and Webcor contracted with the Lawrence Berkeley National Laboratory (LBNL) to test building systems including lighting, lighting controls, shade fabric, and automated shading controls in LBNL’s new FLEXLAB facility. The goal of the testing is to ensure that the systems installed in the new office building will function in a way that reduces energy consumption and provides a comfortable work environment for employees.

  5. High sensitivity optically pumped quantum magnetometer.

    Science.gov (United States)

    Tiporlini, Valentina; Alameh, Kamal

    2013-01-01

    Quantum magnetometers based on optical pumping can achieve sensitivity as high as what SQUID-based devices can attain. In this paper, we discuss the principle of operation and the optimal design of an optically pumped quantum magnetometer. The ultimate intrinsic sensitivity is calculated showing that optimal performance of the magnetometer is attained with an optical pump power of 20 μW and an operation temperature of 48°C. Results show that the ultimate intrinsic sensitivity of the quantum magnetometer that can be achieved is 327 fT/Hz(½) over a bandwidth of 26 Hz and that this sensitivity drops to 130 pT/Hz(½) in the presence of environmental noise. The quantum magnetometer is shown to be capable of detecting a sinusoidal magnetic field of amplitude as low as 15 pT oscillating at 25 Hz.

  6. High-performance commercial building facades

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eleanor; Selkowitz, Stephen; Bazjanac, Vladimir; Inkarojrit, Vorapat; Kohler, Christian

    2002-06-01

    This study focuses on advanced building facades that use daylighting, sun control, ventilation systems, and dynamic systems. A quick perusal of the leading architectural magazines, or a discussion in most architectural firms today will eventually lead to mention of some of the innovative new buildings that are being constructed with all-glass facades. Most of these buildings are appearing in Europe, although interestingly U.S. A/E firms often have a leading role in their design. This ''emerging technology'' of heavily glazed fagades is often associated with buildings whose design goals include energy efficiency, sustainability, and a ''green'' image. While there are a number of new books on the subject with impressive photos and drawings, there is little critical examination of the actual performance of such buildings, and a generally poor understanding as to whether they achieve their performance goals, or even what those goals might be. Even if the building ''works'' it is often dangerous to take a design solution from one climate and location and transport it to a new one without a good causal understanding of how the systems work. In addition, there is a wide range of existing and emerging glazing and fenestration technologies in use in these buildings, many of which break new ground with respect to innovative structural use of glass. It is unclear as to how well many of these designs would work as currently formulated in California locations dominated by intense sunlight and seismic events. Finally, the costs of these systems are higher than normal facades, but claims of energy and productivity savings are used to justify some of them. Once again these claims, while plausible, are largely unsupported. There have been major advances in glazing and facade technology over the past 30 years and we expect to see continued innovation and product development. It is critical in this process to be able to

  7. Aluminum nanocantilevers for high sensitivity mass sensors

    DEFF Research Database (Denmark)

    Davis, Zachary James; Boisen, Anja

    2005-01-01

    We have fabricated Al nanocantilevers using a simple, one mask contact UV lithography technique with lateral and vertical dimensions under 500 and 100 nm, respectively. These devices are demonstrated as highly sensitive mass sensors by measuring their dynamic properties. Furthermore, it is shown ...

  8. Nonclassical characteristic functions for highly sensitive measurements

    CERN Document Server

    Richter, T; Richter, Th.

    2007-01-01

    Characteristic functions are shown to be useful for highly sensitive measurements. Redistributions of motional Fock states of a trapped atom can be directly monitored via the most fragile nonclassical part of the characteristic function. The method can also be used for decoherence measurements in optical quantum-information systems.

  9. Application of sensitivity analysis in building energy simulations: combining first and second order elementary effects Methods

    CERN Document Server

    Sanchez, David Garcia; Musy, Marjorie; Bourges, Bernard

    2012-01-01

    Sensitivity analysis plays an important role in the understanding of complex models. It helps to identify influence of input parameters in relation to the outputs. It can be also a tool to understand the behavior of the model and then can help in its development stage. This study aims to analyze and illustrate the potential usefulness of combining first and second-order sensitivity analysis, applied to a building energy model (ESP-r). Through the example of a collective building, a sensitivity analysis is performed using the method of elementary effects (also known as Morris method), including an analysis of interactions between the input parameters (second order analysis). Importance of higher-order analysis to better support the results of first order analysis, highlighted especially in such complex model. Several aspects are tackled to implement efficiently the multi-order sensitivity analysis: interval size of the variables, management of non-linearity, usefulness of various outputs.

  10. High blood pressure and visual sensitivity

    Science.gov (United States)

    Eisner, Alvin; Samples, John R.

    2003-09-01

    The study had two main purposes: (1) to determine whether the foveal visual sensitivities of people treated for high blood pressure (vascular hypertension) differ from the sensitivities of people who have not been diagnosed with high blood pressure and (2) to understand how visual adaptation is related to standard measures of systemic cardiovascular function. Two groups of middle-aged subjects-hypertensive and normotensive-were examined with a series of test/background stimulus combinations. All subjects met rigorous inclusion criteria for excellent ocular health. Although the visual sensitivities of the two subject groups overlapped extensively, the age-related rate of sensitivity loss was, for some measures, greater for the hypertensive subjects, possibly because of adaptation differences between the two groups. Overall, the degree of steady-state sensitivity loss resulting from an increase of background illuminance (for 580-nm backgrounds) was slightly less for the hypertensive subjects. Among normotensive subjects, the ability of a bright (3.8-log-td), long-wavelength (640-nm) adapting background to selectively suppress the flicker response of long-wavelength-sensitive (LWS) cones was related inversely to the ratio of mean arterial blood pressure to heart rate. The degree of selective suppression was also related to heart rate alone, and there was evidence that short-term changes of cardiovascular response were important. The results suggest that (1) vascular hypertension, or possibly its treatment, subtly affects visual function even in the absence of eye disease and (2) changes in blood flow affect retinal light-adaptation processes involved in the selective suppression of the flicker response from LWS cones caused by bright, long-wavelength backgrounds.

  11. Highly Energetic, Low Sensitivity Aromatic Peroxy Acids.

    Science.gov (United States)

    Gamage, Nipuni-Dhanesha H; Stiasny, Benedikt; Stierstorfer, Jörg; Martin, Philip D; Klapötke, Thomas M; Winter, Charles H

    2016-02-18

    The synthesis, structure, and energetic materials properties of a series of aromatic peroxy acid compounds are described. Benzene-1,3,5-tris(carboperoxoic) acid is a highly sensitive primary energetic material, with impact and friction sensitivities similar to those of triacetone triperoxide. By contrast, benzene-1,4-bis(carboperoxoic) acid, 4-nitrobenzoperoxoic acid, and 3,5-dinitrobenzoperoxoic acid are much less sensitive, with impact and friction sensitivities close to those of the secondary energetic material 2,4,6-trinitrotoluene. Additionally, the calculated detonation velocities of 3,5-dinitrobenzoperoxoic acid and 2,4,6-trinitrobenzoperoxoic acid exceed that of 2,4,6-trinitrotoluene. The solid-state structure of 3,5-dinitrobenzoperoxoic acid contains intermolecular O-H⋅⋅⋅O hydrogen bonds and numerous N⋅⋅⋅O, C⋅⋅⋅O, and O⋅⋅⋅O close contacts. These attractive lattice interactions may account for the less sensitive nature of 3,5-dinitrobenzoperoxoic acid.

  12. Highly sensitive catalytic spectrophotometric determination of ruthenium

    Science.gov (United States)

    Naik, Radhey M.; Srivastava, Abhishek; Prasad, Surendra

    2008-01-01

    A new and highly sensitive catalytic kinetic method (CKM) for the determination of ruthenium(III) has been established based on its catalytic effect on the oxidation of L-phenylalanine ( L-Pheala) by KMnO 4 in highly alkaline medium. The reaction has been followed spectrophotometrically by measuring the decrease in the absorbance at 526 nm. The proposed CKM is based on the fixed time procedure under optimum reaction conditions. It relies on the linear relationship where the change in the absorbance (Δ At) versus added Ru(III) amounts in the range of 0.101-2.526 ng ml -1 is plotted. Under the optimum conditions, the sensitivity of the proposed method, i.e. the limit of detection corresponding to 5 min is 0.08 ng ml -1, and decreases with increased time of analysis. The method is featured with good accuracy and reproducibility for ruthenium(III) determination. The ruthenium(III) has also been determined in presence of several interfering and non-interfering cations, anions and polyaminocarboxylates. No foreign ions interfered in the determination ruthenium(III) up to 20-fold higher concentration of foreign ions. In addition to standard solutions analysis, this method was successfully applied for the quantitative determination of ruthenium(III) in drinking water samples. The method is highly sensitive, selective and very stable. A review of recently published catalytic spectrophotometric methods for the determination of ruthenium(III) has also been presented for comparison.

  13. High Performance Home Building Guide for Habitat for Humanity Affiliates

    Energy Technology Data Exchange (ETDEWEB)

    Lindsey Marburger

    2010-10-01

    This guide covers basic principles of high performance Habitat construction, steps to achieving high performance Habitat construction, resources to help improve building practices, materials, etc., and affiliate profiles and recommendations.

  14. Revisit of Energy Use and Technologies of High Performance Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Li, Cheng; Hong, Tianzhen

    2014-03-30

    Energy consumed by buildings accounts for one third of the world?s total primary energy use. Associated with the conscious of energy savings in buildings, High Performance Buildings (HPBs) has surged across the world, with wide promotion and adoption of various performance rating and certification systems. It is valuable to look into the actual energy performance of HPBs and to understand their influencing factors. To shed some light on this topic, this paper conducted a series of portfolio analysis based on a database of 51 high performance office buildings across the world. Analyses showed that the actual site Energy Use Intensity (EUI) of the 51 buildings varied by a factor of up to 11, indicating a large scale of variation of the actual energy performance of the current HPBs. Further analysis of the correlation between EUI and climate elucidated ubiquitous phenomenon of EUI scatter throughout all climate zones, implying that the weather is not a decisive factor, although important, for the actual energy consumption of an individual building. On the building size via EUI, analysis disclosed that smaller buildings have a tendency to achieving lower energy use. Even so, the correlation is not absolute since some large buildings demonstrated low energy use while some small buildings performed opposite. Concerning the technologies, statistics indicated that the application of some technologies had correlations with some specific building size and climate characteristic. However, it was still hard to pinpoint a set of technologies which was directly correlative with a group of low EUI buildings. It is concluded that no a single factor essentially determines the actual energy performance of HPBs. To deliver energy-efficient buildings, an integrated design taking account of climate, technology, occupant behavior as well as operation and maintenance should be implemented.

  15. High-sensitive cardiac troponin T

    Institute of Scientific and Technical Information of China (English)

    Ru-Yi Xu; Xiao-Fa Zhu; Ye Yang; Ping Ye

    2013-01-01

    Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits detection of very low levels of cTnT. Using the hs-cTnT assay improves the overall diagnostic accuracy in patients with suspected AMI, while a negative result also has a high negative predictive value. The gain in sensitivity may be particularly important in patients with a short duration from symptom onset to admission. Measurement of cardiac troponin T with the hs-cTnT assay may provide strong prognostic information in patients with acute coronary syndromes, stable coronary artery disease, heart failure and even in the general population; however, increased sensitivity comes at a cost of decreased specificity. Serial testing, as well as clinical context and co-existing diseases, are likely to become increasingly important for the interpretation of hs-cTnT assay results.

  16. 76 FR 35894 - Office of Federal High-Performance Green Buildings; Establishment of the Green Building Advisory...

    Science.gov (United States)

    2011-06-20

    ...] Office of Federal High-Performance Green Buildings; Establishment of the Green Building Advisory...: Notice. SUMMARY: GSA announces the establishment of the Green Building Advisory Committee (the Committee... strategic plans, products and activities of the Office of Federal High-Performance Green Buildings...

  17. Intelligent Facades for High Performance Green Buildings. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dyson, Anna [Rensselaer Polytechnic Inst., Troy, NY (United States)

    2017-03-01

    Intelligent Facades for High Performance Green Buildings: Previous research and development of intelligent facades systems has been limited in their contribution towards national goals for achieving on-site net zero buildings, because this R&D has failed to couple the many qualitative requirements of building envelopes such as the provision of daylighting, access to exterior views, satisfying aesthetic and cultural characteristics, with the quantitative metrics of energy harvesting, storage and redistribution. To achieve energy self-sufficiency from on-site solar resources, building envelopes can and must address this gamut of concerns simultaneously. With this project, we have undertaken a high-performance building- integrated combined-heat and power concentrating photovoltaic system with high temperature thermal capture, storage and transport towards multiple applications (BICPV/T). The critical contribution we are offering with the Integrated Concentrating Solar Façade (ICSF) is conceived to improve daylighting quality for improved health of occupants and mitigate solar heat gain while maximally capturing and transferring on- site solar energy. The ICSF accomplishes this multi-functionality by intercepting only the direct-normal component of solar energy (which is responsible for elevated cooling loads) thereby transforming a previously problematic source of energy into a high- quality resource that can be applied to building demands such as heating, cooling, dehumidification, domestic hot water, and possible further augmentation of electrical generation through organic Rankine cycles. With the ICSF technology, our team is addressing the global challenge in transitioning commercial and residential building stock towards on-site clean energy self-sufficiency, by fully integrating innovative environmental control systems strategies within an intelligent and responsively dynamic building envelope. The advantage of being able to use the entire solar spectrum for

  18. Sensitivity Analysis and Uncertainty Characterization of Subnational Building Energy Demand in an Integrated Assessment Model

    Science.gov (United States)

    Scott, M. J.; Daly, D.; McJeon, H.; Zhou, Y.; Clarke, L.; Rice, J.; Whitney, P.; Kim, S.

    2012-12-01

    Residential and commercial buildings are a major source of energy consumption and carbon dioxide emissions in the United States, accounting for 41% of energy consumption and 40% of carbon emissions in 2011. Integrated assessment models (IAMs) historically have been used to estimate the impact of energy consumption on greenhouse gas emissions at the national and international level. Increasingly they are being asked to evaluate mitigation and adaptation policies that have a subnational dimension. In the United States, for example, building energy codes are adopted and enforced at the state and local level. Adoption of more efficient appliances and building equipment is sometimes directed or actively promoted by subnational governmental entities for mitigation or adaptation to climate change. The presentation reports on new example results from the Global Change Assessment Model (GCAM) IAM, one of a flexibly-coupled suite of models of human and earth system interactions known as the integrated Regional Earth System Model (iRESM) system. iRESM can evaluate subnational climate policy in the context of the important uncertainties represented by national policy and the earth system. We have added a 50-state detailed U.S. building energy demand capability to GCAM that is sensitive to national climate policy, technology, regional population and economic growth, and climate. We are currently using GCAM in a prototype stakeholder-driven uncertainty characterization process to evaluate regional climate mitigation and adaptation options in a 14-state pilot region in the U.S. upper Midwest. The stakeholder-driven decision process involves several steps, beginning with identifying policy alternatives and decision criteria based on stakeholder outreach, identifying relevant potential uncertainties, then performing sensitivity analysis, characterizing the key uncertainties from the sensitivity analysis, and propagating and quantifying their impact on the relevant decisions. In the

  19. Photodetector having high speed and sensitivity

    Science.gov (United States)

    Morse, Jeffrey D.; Mariella, Jr., Raymond P.

    1991-01-01

    The present invention provides a photodetector having an advantageous combination of sensitivity and speed; it has a high sensitivity while retaining high speed. In a preferred embodiment, visible light is detected, but in some embodiments, x-rays can be detected, and in other embodiments infrared can be detected. The present invention comprises a photodetector having an active layer, and a recombination layer. The active layer has a surface exposed to light to be detected, and comprises a semiconductor, having a bandgap graded so that carriers formed due to interaction of the active layer with the incident radiation tend to be swept away from the exposed surface. The graded semiconductor material in the active layer preferably comprises Al.sub.1-x Ga.sub.x As. An additional sub-layer of graded In.sub.1-y Ga.sub.y As may be included between the Al.sub.1-x Ga.sub.x As layer and the recombination layer. The recombination layer comprises a semiconductor material having a short recombination time such as a defective GaAs layer grown in a low temperature process. The recombination layer is positioned adjacent to the active layer so that carriers from the active layer tend to be swept into the recombination layer. In an embodiment, the photodetector may comprise one or more additional layers stacked below the active and recombination layers. These additional layers may include another active layer and another recombination layer to absorb radiation not absorbed while passing through the first layers. A photodetector having a stacked configuration may have enhanced sensitivity and responsiveness at selected wavelengths such as infrared.

  20. High sensitivity troponin and valvular heart disease.

    Science.gov (United States)

    McCarthy, Cian P; Donnellan, Eoin; Phelan, Dermot; Griffin, Brian P; Sarano, Maurice Enriquez-; McEvoy, John W

    2017-01-16

    Blood-based biomarkers have been extensively studied in a range of cardiovascular diseases and have established utility in routine clinical care, most notably in the diagnosis of acute coronary syndrome (e.g., troponin) and the management of heart failure (e.g., brain-natriuretic peptide). The role of biomarkers is less well established in the management of valvular heart disease (VHD), in which the optimal timing of surgical intervention is often challenging. One promising biomarker that has been the subject of a number of recent VHD research studies is high sensitivity troponin (hs-cTn). Novel high-sensitivity assays can detect subclinical myocardial damage in asymptomatic individuals. Thus, hs-cTn may have utility in the assessment of asymptomatic patients with severe VHD who do not have a clear traditional indication for surgical intervention. In this state-of-the-art review, we examine the current evidence for hs-cTn as a potential biomarker in the most commonly encountered VHD conditions, aortic stenosis and mitral regurgitation. This review provides a synopsis of early evidence indicating that hs-cTn has promise as a biomarker in VHD. However, the impact of its measurement on clinical practice and VHD outcomes needs to be further assessed in prospective studies before routine clinical use becomes a reality.

  1. Energy efficiency indicators for high electric-load buildings

    Energy Technology Data Exchange (ETDEWEB)

    Aebischer, Bernard; Balmer, Markus A.; Kinney, Satkartar; Le Strat, Pascale; Shibata, Yoshiaki; Varone, Frederic

    2003-06-01

    Energy per unit of floor area is not an adequate indicator for energy efficiency in high electric-load buildings. For two activities, restaurants and computer centres, alternative indicators for energy efficiency are discussed.

  2. Highly Sensitive Electro-Optic Modulators

    Energy Technology Data Exchange (ETDEWEB)

    DeVore, Peter S [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-26

    There are very important diagnostic and communication applications that receive faint electrical signals to be transmitted over long distances for capture. Optical links reduce bandwidth and distance restrictions of metal transmission lines; however, such signals are only weakly imprinted onto the optical carrier, resulting in low fidelity transmission. Increasing signal fidelity often necessitates insertion of radio-frequency (RF) amplifiers before the electro-optic modulator, but (especially at high frequencies) RF amplification results in large irreversible distortions. We have investigated the feasibility of a Sensitive and Linear Modulation by Optical Nonlinearity (SALMON) modulator to supersede RF-amplified modulators. SALMON uses cross-phase modulation, a manifestation of the Kerr effect, to enhance the modulation depth of an RF-modulated optical wave. This ultrafast process has the potential to result in less irreversible distortions as compared to a RF-amplified modulator due to the broadband nature of the Kerr effect. Here, we prove that a SALMON modulator is a feasible alternative to an RFamplified modulator, by demonstrating a sensitivity enhancement factor greater than 20 and significantly reduced distortion.

  3. Heterogeneous catalysis in highly sensitive microreactors

    DEFF Research Database (Denmark)

    Olsen, Jakob Lind

    This thesis present a highly sensitive silicon microreactor and examples of its use in studying catalysis. The experimental setup built for gas handling and temperature control for the microreactor is described. The implementation of LabVIEW interfacing for all the experimental parts makes...... automated experiments and data collection possible. An argon ush at the O-rings (used to interface the silicon microreactor with the gas system), which was developed, is presented. It enables experiments with temperatures up to 400., and up to 500. for short periods of time. The CO oxidation reaction...... of adsorbates readily converted to methanol as the source of the transient increase in methanol production, is eliminated. A study of mass selected ruthenium nanoparticles from a magnetron-sputter gas-aggregation source, deposited in microreactors, is presented. It is, shown that CO methanation can be measured...

  4. High-sensitivity fiber optic acoustic sensors

    Science.gov (United States)

    Lu, Ping; Liu, Deming; Liao, Hao

    2016-11-01

    Due to the overwhelming advantages compared with traditional electronicsensors, fiber-optic acoustic sensors have arisen enormous interest in multiple disciplines. In this paper we present the recent research achievements of our group on fiber-optic acoustic sensors. The main point of our research is high sensitivity interferometric acoustic sensors, including Michelson, Sagnac, and Fabry-Pérot interferometers. In addition, some advanced technologies have been proposed for acoustic or acoustic pressure sensing such as single-mode/multimode fiber coupler, dual FBGs and multi-longitudinal mode fiber laser based acoustic sensors. Moreover, our attention we have also been paid on signal demodulation schemes. The intensity-based quadrature point (Q-point) demodulation, two-wavelength quadrature demodulation and symmetric 3×3 coupler methodare discussed and compared in this paper.

  5. High sensitive radiation detector for radiology dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Valente, M.; Malano, F. [Instituto de Fisica Enrique Gaviola, Oficina 102 FaMAF - UNC, Av. Luis Medina Allende, Ciudad Universitaria, 5000 Cordoba (Argentina); Molina, W.; Vedelago, J., E-mail: valente@famac.unc.edu.ar [Laboratorio de Investigaciones e Instrumentacion en Fisica Aplicada a la Medicina e Imagenes por Rayos X, Laboratorio 448 FaMAF - UNC, Ciudad Universitaria, 5000 Cordoba (Argentina)

    2014-08-15

    Fricke solution has a wide range of applications as radiation detector and dosimetry. It is particularly appreciated in terms of relevant comparative advantages, like tissue equivalence when prepared in aqueous media like gel matrix, continuous mapping capability, dose rate recorded and incident direction independence as well as linear dose response. This work presents the development and characterization of a novel Fricke gel system, based on modified chemical compositions making possible its application in clinical radiology. Properties of standard Fricke gel dosimeter for high dose levels are used as starting point and suitable chemical modifications are introduced and carefully investigated in order to attain high resolution for low dose ranges, like those corresponding to radiology interventions. The developed Fricke gel radiation dosimeter system achieves the expected typical dose dependency, actually showing linear response in the dose range from 20 up to 4000 mGy. Systematic investigations including several chemical compositions are carried out in order to obtain a good enough dosimeter response for low dose levels. A suitable composition among those studied is selected as a good candidate for low dose level radiation dosimetry consisting on a modified Fricke solution fixed to a gel matrix containing benzoic acid along with sulfuric acid, ferrous sulfate, xylenol orange and ultra-pure reactive grade water. Dosimeter samples are prepared in standard vials for its in phantom irradiation and further characterization by spectrophotometry measuring visible light transmission and absorbance before and after irradiation. Samples are irradiated by typical kV X-ray tubes and calibrated Farmer type ionization chamber is used as reference to measure dose rates inside phantoms in at vials locations. Once sensitive material composition is already optimized, dose-response curves show significant improvement regarding overall sensitivity for low dose levels. According to

  6. Building

    OpenAIRE

    Seavy, Ryan

    2014-01-01

    Building for concrete is temporary. The building of wood and steel stands against the concrete to give form and then gives way, leaving a trace of its existence behind. Concrete is not a building material. One does not build with concrete. One builds for concrete. MARCH

  7. High sensitivity field asymmetric ion mobility spectrometer

    Science.gov (United States)

    Chavarria, Mario A.; Matheoud, Alessandro V.; Marmillod, Philippe; Liu, Youjiang; Kong, Deyi; Brugger, Jürgen; Boero, Giovanni

    2017-03-01

    A high sensitivity field asymmetric ion mobility spectrometer (FAIMS) was designed, fabricated, and tested. The main components of the system are a 10.6 eV UV photoionization source, an ion filter driven by a high voltage/high frequency n-MOS inverter circuit, and a low noise ion detector. The ion filter electronics are capable to generate square waveforms with peak-to-peak voltages up to 1000 V at frequencies up to 1 MHz with adjustable duty cycles. The ion detector current amplifier has a gain up to 1012 V/A with an effective equivalent input noise level down to about 1 fA/Hz1/2 during operation with the ion filter at the maximum voltage and frequency. The FAIMS system was characterized by detecting different standard chemical compounds. Additionally, we investigated the use of a synchronous modulation/demodulation technique to improve the signal-to-noise ratio in FAIMS measurements. In particular, we implemented the modulation of the compensation voltage with the synchronous demodulation of the ion current. The analysis of the measurements at low concentration levels led to an extrapolated limit of detection for acetone of 10 ppt with an averaging time of 1 s.

  8. The support systems of unique high-rise buildings

    Directory of Open Access Journals (Sweden)

    Shumeyko Victor

    2017-01-01

    Full Text Available Tall buildings and skyscrapers perceive significant vertical loads and, moreover, have to resist large lateral effects which form strong gusts of wind and seismic events. In the world for the high-rise buildings with the nuclei of the stiffness are using streamers – outriggers, which connect the external column and the core form the support system and resist lateral loads. High-rise buildings construction grows promptly around the world and causes new problems which shall be solved on the basis of the modern constructive opportunities, by means of exact engineering assessment. Systems of outrigers and belts are very important in the modern engineering, because they provide effective control over side shifts of a building. They play an important role in high-rise unique buildings constructions, being a link between the central kernel and outer columns. The article deals with the design scheme of conventional conveyor of belts and outriggers – bandages, explores their applications, advantages and disadvantages of various options, problems with their design. Presented material enables the design of unique high-rise buildings to choose the most optimal design solution.

  9. Studies on wind environment around high buildings in urban areas

    Institute of Scientific and Technical Information of China (English)

    LIU; Huizhi; JIANG; Yujun; LIANG; Bin; ZHU; Fengrong; ZHAN

    2005-01-01

    High buildings or architectural complex in urban areas remarkably distort the urban surface wind fields. As the air flow approaches,local strong wind may appear around the buildings. The strong wind makes the pedestrians on sidewalks, entrances and terrace very uncomfortable and causes the pedestrian level wind environment problem. In this studies, hot-wire wind measurement, wind scouring in wind tunnel and numerical computation were carried out to evaluate the wind environment of tall buildings in the prevailing flow conditions in Beijing areas. The results obtained by three techniques were compared and mutually verified. The conclusions drawn from three approaches agree with each other. Also the advantages and limitations of each method were analyzed. It is suggested that the combination of different techniques may produce better assessment of wind environment around high buildings.

  10. Seismic Performance of High Strength Steel Building Frames

    OpenAIRE

    2014-01-01

    Tese de doutoramento em Engenharia Civil, no ramo de Construção Metálica e Mista, apresentada ao Departamento de Engenharia Civil da Faculdade de Ciências e Tecnologia da Universidade de Coimbra In steel building frames under seismic action, the members designed to remain elastic during an earthquake are responsible for the robustness of the structure and prevention of collapse, being characterised by high strength demands. On the other hand, seismic resistant building frames designed as ...

  11. Building the UPPA high capacity tensiometer

    Directory of Open Access Journals (Sweden)

    Mendes Joao

    2016-01-01

    Full Text Available High capacity tensiometers (HCTs are sensors capable of directly measuring tensile pore water pressure (suction in soils. HCTs are typically composed of a casing that encapsulates a high air entry value ceramic filter, a water reservoir and a pressure sensing element. Since the creation of the first HCT by Ridley and Burland in 1993 at Imperial College London, HCTs have been almost exclusively built and used in academic research. The limited use in industrial applications can be explained by a lack of unsaturated soil mechanics knowledge among engineering practitioners but also by the technical difficulties associated to the direct measurement of tensile water pressures beyond the cavitation limit of -100kPa. In this paper, we present the recent design and manufacture of a new HCT at the Université de Pau et des Pays de l’Adour (UPPA in France. Different prototypes were tried by changing the main components of the device including the type of ceramic filter, pressure transducer and geometry of the external casing. In particular, two ceramic filters of distinct porosity, three pressure transducers with distinct materials/geometries and four casing designs were tested.

  12. 77 FR 43084 - Office of Federal High-Performance Green Buildings; Federal Buildings Personnel Training Act...

    Science.gov (United States)

    2012-07-23

    ... available for download from the Office of Federal High-Performance Green Building Web site Library at-- http://www.gsa.gov/portal/content/117699 . The Facilities Management Institute, FMI.innovations.gov....innovations.gov (available 08/01/ 2012), an open site where the public, Federal agencies,...

  13. SENSITIVITY ANALYSIS OF BUILDING STRUCTURES WITHIN THE SCOPE OF ENERGY, ENVIRONMENT AND INVESTMENT

    Directory of Open Access Journals (Sweden)

    František Kulhánek

    2015-10-01

    Full Text Available The primary objective of this paper is to prove the feasibility of sensitivity analysis with dominant weight method for structure parts of envelope of buildings inclusive of energy; ecological and financial assessments, and determination of different designs for same structural part via multi-criteria assessment with theoretical example designs ancillary. Multi-criteria assessment (MCA of different structural designs or in other word alternatives aims to find the best available alternative. The application of sensitivity analysis technique in this paper bases on dominant weighting method. In this research, to choose the best thermal insulation design in the case of that more than one projection, simultaneously, criteria of total thickness (T; heat transfer coefficient (U through the cross section; global warming potential (GWP; acid produce (AP; primary energy content (PEI non renewable and cost per m2 (C are investigated for all designs via sensitivity analysis. Three different designs for external wall (over soil which are convenient with regard to globally suggested energy features for passive house design are investigated through the mentioned six projections. By creating a given set of scenarios; depending upon the importance of each criterion, sensitivity analysis is distributed. As conclusion, uncertainty in the output of model is attributed to different sources in the model input. In this manner, determination of the best available design is achieved. The original outlook and the outlook afterwards the sensitivity analysis are visualized, that enables easily to choose the optimum design within the scope of verified components.

  14. Highly sensitive direct conversion ultrasound interferometer

    Science.gov (United States)

    Svitelskiy, Oleksiy; Grossmann, John; Suslov, Alexey

    2015-03-01

    Being invented more than fifty years ago, the ultrasonic pulse-echo technique has proven itself as a valuable and indispensable non-destructive tool to explore elastic properties of materials in engineering and scientific tasks. We propose a new design for the instrument based on mass-produced integral microchips. In our design the radiofrequency echo-pulse signal is processed by AD8302 RF gain and phase detector (www.analog.com).Its phase output is linearly proportional to the phase difference between the exciting and response signals. The gain output is proportional to the log of the ratio of amplitudes of the received to the exciting signals. To exclude the non-linear fragments and to enable exploring large phase changes, we employ parallel connection of two detectors, fed by in-phase and quadrature signals respectively. The instrument allowed us exploring phase transitions with precision of ΔV / V ~10-7 (V is the ultrasound speed). The high sensitivity of the logarithmic amplifiers embedded into AD8302 requires good grounding and screening of the receiving circuitry.

  15. High Sensitivity, High Frequency and High Time Resolution Decimetric Spectroscope

    Science.gov (United States)

    Sawant, H. S.; Rosa, R. R.

    1990-11-01

    RESUMEN. Se ha desarrollado el primer espectroscopio decimetrico latino americano operando en una banda de 100 MHz con alta resoluci6n de fre- cuencia (100 KHz) y tiempo (10 ms), alrededor de cualquier centro de frecuencia en el intervalo de 2000-200 MHz. El prop6sito de esta nota es describir investigaciones solares y no solares que se planean, progra ma de investigaci6n y la situaci6n actual de desarrollo de este espectroscopio. ABSTRACT. First Latin American Decimetric Spectroscope operating over a band of 100 MHz with high resolution in frequency (100 KHz) and time (10 ms), around any center frequency in the range of 2000-200 MHz is being developed. The purpose of this note is to describe planned solar, and non-solar, research programmes and present status of development of this spectroscope. Keq wo : INSTRUMENTS - SPECTROSCOPY

  16. Structural response of steel high rise buildings to fire

    DEFF Research Database (Denmark)

    Gentili, Filippo; Giuliani, Luisa; Bontempi, Franco

    2013-01-01

    Due to the significant vertical elevation and complexity of the structural system, high rise buildings may suffer from the effects of fire more than other structures. For this reason, in addition to evacuation strategies and active fire protection, a careful consideration of structural response...... to fire is also very important. In this context, it is of interest to investigate the characteristics of the structural system that could possibly reduce local damages or mitigate the progression of failures in case of fire. In this paper, a steel high rise building is taken as case study and the response...... of the building is investigated up to the crisis of the structure with respect to a standard fire in a lower and in a higher storey: the comparison of the fire induced failures at the different height allows highlighting the role played in the resulting collapse mechanisms by the beam-column stiffness ratio...

  17. Amplitude-sensitive modulation thermography to measure moisture in building materials

    Science.gov (United States)

    Wild, Walter; Buescher, Konstantin A.; Wiggenhauser, Herbert

    1998-03-01

    There have been reports about moisture detection in building walls by reflective IR-thermography. Typically, only limited results could be obtained because of the emission coefficient variations, leaking radiation or inhomogeneous illumination of the object. In addition, the quantitative relation between remission spectra and the moisture has often been unclear. Reflectometry uses constant excitation illumination which is recorded by the IR camera. With the use of the 'lock-in-technology' a low frequency modulated signal of an IR radiation source is coupled with the thermo camera and a frequency and phase sensitive signal from the thermal images can be derived. The advantage is, that emission coefficient dependencies are eliminated and that leaking radiation does not have any influence on the measured signal. The selective water measurement is possible, because there is an interference filter mounted in front of the radiator which has its transmission maximum at the wavelength of an absorption band of water. The area investigated is therefore illuminated under well defined circumstances and quantitative moisture measurement on the surface of building materials becomes a possibility. The illumination modulation is done with a sine wave to facilitate the calculation of the temporal intensity behavior of the amplitude signal. Subsequently, the amplitude image is used to determine the distribution and the level of moisture quantitatively. Point measurements in the laboratory were carried out on several building materials with changing moisture levels. It could be shown that this method successfully eliminates disturbing contributions to the measured signal like surface effects or leaking radiation.

  18. Early Building Design: Informed decision-making by exploring multidimensional design space using sensitivity analysis

    DEFF Research Database (Denmark)

    Østergård, Torben; Jensen, Rasmus Lund; Maagaard, Steffen

    2017-01-01

    This paper describes a novel approach to explore a multidimensional design space and guide multi-actor decision making in the design of sustainable buildings. The aim is to provide proactive and holistic guidance of the design team. We propose to perform exhaustive Monte Carlo simulations in an i...... to remedy unwanted output changes. The proposed methodology has been developed and tested through real building cases using a normative model to assess energy demand, thermal comfort, and daylight.......This paper describes a novel approach to explore a multidimensional design space and guide multi-actor decision making in the design of sustainable buildings. The aim is to provide proactive and holistic guidance of the design team. We propose to perform exhaustive Monte Carlo simulations...... in an iterative design approach that consists of two steps: 1) preparation by modeler, and 2) multi-collaborator meeting. In the preparation phase, the simulation modeler performs Morris sensitivity analysis to fixate insignificant model inputs and to identify non-linearity and interaction effects. Next...

  19. Spherical TiO2 aggregates with different building units for dye-sensitized solar cells.

    Science.gov (United States)

    Liu, Zhaohui; Su, Xunjia; Hou, Genliang; Bi, Song; Xiao, Zhou; Jia, Haipeng

    2013-09-07

    Tailoring the architectures of spherical TiO2 aggregates is crucial to obtain superior photovoltaic properties and promote their application in dye-sensitized solar cells (DSSCs). Herein, we synthesized spherical TiO2 aggregates using different building units, including nanocrystallites, nanorods, nanosheets, and nanotubes, via a hydrothermal method, and studied the effect of the building units on the performances of DSSCs. The aggregates assembled by uniform nanosheet and nanotube building units were synthesized with the use of spherical TiO2 nanorod aggregates as titanium sources in an alkaline hydrothermal reaction. Compared with TiO2 nanoparticles, the spherical TiO2 aggregates possess higher surface area, more efficient light scattering ability, and better electron transport properties. Among the four types of spherical TiO2 aggregates; the nanorod, nanotube, and nanosheet aggregates demonstrate better electron transport properties than the nanocrystallite aggregates; the nanotube and nanosheet aggregates exhibit more efficient light scattering than the nanocrystallite and nanorod aggregates; and the nanotube aggregates show the highest surface area. Thus the DSSC based on nanotube aggregates exhibited the highest energy conversion efficiency of 7.48%, which is 16.0%, 9.7%, and 19.5% higher than those of the DSSCs based on the nanosheet, nanorod, and nanocrystallite aggregates, respectively.

  20. "Slow Science": Building Scientific Concepts in Physics in High School

    Science.gov (United States)

    Bigozzi, Lucia; Tarchi, Christian; Falsini, Paola; Fiorentini, Carlo

    2014-01-01

    In this study, a progressive-learning approach to physics, based on knowledge-building pedagogy, was compared to a content-centered approach in which explanations, experiments, and discussions are centered on the transmission of knowledge. Forty-six students attending the first year of high school participated in this study over a whole school…

  1. Intel Legend and CERN would build up high speed Internet

    CERN Multimedia

    2002-01-01

    Intel, Legend and China Education and Research Network jointly announced on the 25th of April that they will be cooperating with each other to build up the new generation high speed internet, over the next three years (1/2 page).

  2. Building and managing high performance, scalable, commodity mass storage systems

    Science.gov (United States)

    Lekashman, John

    1998-01-01

    The NAS Systems Division has recently embarked on a significant new way of handling the mass storage problem. One of the basic goals of this new development are to build systems at very large capacity and high performance, yet have the advantages of commodity products. The central design philosophy is to build storage systems the way the Internet was built. Competitive, survivable, expandable, and wide open. The thrust of this paper is to describe the motivation for this effort, what we mean by commodity mass storage, what the implications are for a facility that performs such an action, and where we think it will lead.

  3. [A simple highly sensitive recording microspectrophotometer].

    Science.gov (United States)

    Govardovskiĭ, V I; Zueva, L V

    1988-04-01

    A design of the recording microspectrophotometer is described. The instrument possesses an absolutely flat base line and quantum-noise limited detection threshold. Two principal elements of the design are the "jumping" stage, and the logarithmic amplifier with the phase-sensitive detector which converts the photomultiplier output into the optical density signal. The performance of the instrument is illustrated by the recordings of visual pigment spectra in single photoreceptors.

  4. Best Practices Guide for High-Performance Indian Office Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Reshma [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sartor, Dale [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ghatikar, Girish [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-04-01

    This document provides best practice guidance and energy- efficiency recommendations for the design, construction, and operation of high-­performance office buildings in India. Through a discussion of learnings from exemplary projects and inputs from experts, it provides recommendations that can potentially help achieve (1) enhanced working environments, (2) economic construction/faster payback, (3) reduced operating costs, and (4) reduced greenhouse gas (GHG) emissions. It also provides ambitious (but achievable) energy performance benchmarks, both as adopted targets during building modeling (design phase) and during measurement and verification (operations phase). These benchmarks have been derived from a set of representative best-in-class office buildings in India. The best practices strategies presented in this guide would ideally help in delivering high-­performance in terms of a triad—of energy efficiency, cost efficiency, and occupant comfort and well-­being. These best practices strategies and metrics should be normalized—that is, corrected to account for building characteristics, diversity of operations, weather, and materials and construction methods.

  5. THE IMPORTANCE OF AFFECT TO BUILD CONSUMER TRUST IN HIGH-CONSEQUENCES EXCHANGES

    Directory of Open Access Journals (Sweden)

    Mellina da Silva Terres

    2012-12-01

    Full Text Available The present article investigates the importance of affect displayed by service provider to build consumer trust in high consequence exchanges. High-consequence exchanges are difficult situations in which the choices present a dilemma that can cause stress and severe emotional reactions (KAHN; LUCE, 2003. In this specific case, trust based on affect seems to become important; mainly because consumers may not have ability to evaluate the cognitive aspects of the situation, and moreover, a medical services failure can be highly problematic or even fatal (LEISEN; HYMAN, 2004. On the other hand, in low-consequence choices, we are predicting that cognition will be more important than affect in building trust. In this kind of situation, patients are more self-confident, less sensitive, and don’t perceive a high probability of loss (KUNREUTHER et al., 2002, and therefore focuses more on the rational outcomes.

  6. The Temporal Sensitivity of Enforced Accelerated Work Pace: A grounded theory building approach

    Directory of Open Access Journals (Sweden)

    Graham John James Kenealy, BA (Hons, Ph.D. Candidate

    Full Text Available This research explores how a large national UK government organisation copes with radical structural change over time and provides an insight into the temporal effects of ‘Enforced Accelerated Work Pace’ on behaviour and receptivity within an organisational context. The stages of ‘Acceptance’, ‘Reaction’ and‘Withdrawal’ capture the essence of the ‘Coping Reflex Actions relating to Enforced Accelerated Work Pace’, all sensitive to the effects of time. ‘Temporal Sensitivity’; the duration of the changes to work patterns played a large part in the behavioural responses. The underlying logic of this research is grounded theory building, a general method that works well with qualitative data collection approaches and involves inducting insights from field based, case data (Glaser, 1998. A methodology discovered and developed by Glaser and Strauss (1967, negating all others.

  7. Fire Risk Analysis and Optimization of Fire Prevention Management for Green Building Design and High Rise Buildings: Hong Kong Experience

    Directory of Open Access Journals (Sweden)

    Yau Albert

    2014-12-01

    Full Text Available There are many iconic high rise buildings in Hong Kong, for example, International Commercial Centre, International Financial Centre, etc. Fire safety issue in high rise buildings has been raised by local fire professionals in terms of occupant evacuation, means of fire-fighting by fire fighters, sprinkler systems to automatically put off fires in buildings, etc. Fire risk becomes an important issue in building fire safety because it relates to life safety of building occupants where they live and work in high rise buildings in Hong Kong. The aim of this research is to identify the fire risk for different types of high rise buildings in Hong Kong and to optimise the fire prevention management for those high rise buildings with higher level of fire risk and to validate the model and also to carry out the study of the conflict between the current fire safety building code and the current trend of green building design. Survey via the 7-point scale questionnaire was conducted through 50 participants and their responses were received and analysed via the statistical tool SPSS software computer program. A number of statistical methods of testing for significantly difference in samples were adopted to carry out the analysis of the data received. When the statistical analysis was completed, the results of the data analysis were validated by two Fire Safety Experts in this area of specialisation and also by quantitative fire risk analysis.

  8. A METHOD FOR MEASURING THE SENSITIVITY OF BUILDING STRUCTURAL MEMBERS TO FIRE DECAY PHASES

    Directory of Open Access Journals (Sweden)

    Thomas Gernay

    2016-10-01

    Full Text Available Firefighters face a major threat when intervening in a building during a fire: the possibility of structural collapse during the cooling phase of the fire, or soon thereafter. At present, this threat is amplified by the fact that the behaviour of structures after the time of peak gas temperature is not well understood, and is not taken into account in the design. This work presents an analysis of the behaviour of different structural members under natural fires, and develops a method for characterizing their sensitivity to fire decay phases. Thermo-mechanical numerical simulations based on the non-linear finite element method are conducted using the parametric fire model of the Eurocode to represent natural fires. The results show that, for all the members (a column, a beam and materials (reinforced concrete, steel and timber that are studied here, structural failure during or after the cooling phase of a fire is a possible event. The major factors that promote delayed structural failure are thermal inertia and the constituting material of the member. A method, based on a new indicator, is proposed for quantifying the propensity to delayed failure for structural members under natural fire. This work enhances the understanding of the behaviour of structures under natural fires, and has important implications for the safety of fire brigades and of people responsible for making a building inspection after a fire.

  9. High-rise Buildings versus Outdoor Thermal Environment in Chongqing

    Directory of Open Access Journals (Sweden)

    Jin-sha Wang

    2007-10-01

    Full Text Available This paper gives a brief description of the over quick urbanization sinceChongqing, one of the biggest cities in China, has been a municipality directly under theCentral Government in 1997, excessive development and exceeding increase of high-risebuildings because of its special geographical position which finally leads to the worseningof the urban outdoor thermal environment. Then, this paper makes a bright balance to thefield measurement and simulated results of the wind speed field, temperature field of onemultifunctional high-rise building in Chongqing university located in the city center, andthe contrasted results validate the correctness of CFD in the outdoor thermal environmentalsimulation, expose the disadvantages of high-rise buildings on the aspects of blocking thewind field, decreasing wind speed which results in accumulation of the air-conditioningheat revolving around and periscian region where sunshine can not rip into. Finally, inorder to improve the urban outdoor thermal environment near the high-rise buildingsespecially for the angle of natural ventilation, this paper simulates the wind environment indifferent architectural compositions and architectural layouts by CFD, and the simulatedresults show that freestyle and tower buildings which can guarantee the wind speed andtake the air-conditioning heat away are much suitable and reasonable for the specialChongqing geography. These conclusions can also be used as a reference in othermountain cities, especially for the one with a great number of populations.

  10. Realizing High-Performance Buildings; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-03-02

    High-performance buildings (HPBs) are exceptional examples of both design and practice. Their energy footprints are small, and these are buildings that people want to work in because of their intelligent structure, operations, and coincident comfort. However, the operation of most buildings, even ones that are properly constructed and commissioned at the start, can deviate significantly from the original design intent over time, particularly due to control system overrides and growing plug and data center loads. With early planning for systems such as submetering and occupant engagement tools, operators can identify and remedy the problems. This guide is a primer for owners and owners’ representatives who are pursuing HPBs. It describes processes that have been successful in the planning, procurement, and operation of HPBs with exceptional energy efficiency. Much of the guidance offered results from a series of semi-structured conference calls with a technical advisory group of 15 owners and operators of prominent HPBs in the United States. The guide provides a prescription for planning, achieving, and maintaining an HPB. Although the guide focuses on the operations stage of buildings, many of the operations practices are specified during the planning stage.

  11. High-albedo materials for reducing building cooling energy use

    Energy Technology Data Exchange (ETDEWEB)

    Taha, H.; Sailor, D.; Akbari, H.

    1992-01-01

    One simple and effective way to mitigate urban heat islands, i.e., the higher temperatures in cities compared to those of the surrounds, and their negative impacts on cooling energy consumption is to use high-albedo materials on major urban surfaces such as rooftops, streets, sidewalks, school yards, and the exposed surfaces of parking lots. High-albedo materials can save cooling energy use by directly reducing the heat gain through a building`s envelope (direct effect) and also by lowering the urban air temperature in the neighborhood of the building (indirect effect). This project is an attempt to address high-albedo materials for buildings and to perform measurements of roof coatings. We search for existing methods and materials to implement fighter colors on major building and urban surfaces. Their cost effectiveness are examined and the possible related technical, maintenance, and environmental problems are identified. We develop a method for measuring albedo in the field by studying the instrumentation aspects of such measurements. The surface temperature impacts of various albedo/materials in the actual outdoor environment are studied by measuring the surface temperatures of a variety of materials tested on an actual roof. We also generate an albedo database for several urban surfaces to serve as a reference for future use. The results indicate that high-albedo materials can have a large impact on the surface temperature regime. On clear sunny days, when the solar noon surface temperatures of conventional roofing materials were about 40{degrees}C (72{degrees}F) warmer than air, the surface temperature of high-albedo coatings were only about 5{degrees}C warmer than air. In the morning and in the late afternoon, the high-albedo materials were as cool as the air itself. While conventional roofing materials warm up by an average 0.055{degrees}C/(W m{sup {minus}2}), the high-albedo surfaces warm up by an average 0.015{degrees}C/(W m{sup {minus}2}).

  12. Building identification from very high-resolution satellite images

    Science.gov (United States)

    Lhomme, Stephane

    Urbanisation still remains one of the main problems worldwide. The extent and rapidity of the urban growth induce a number of socio-economic and environmental conflicts everywhere. In order to reduce these problems, urban planners need to integrate spatial information in planning tools. Actually high expectations are made on Very High Spatial Resolution imagery (VHSR). These high-spatial resolution images are available at a reasonable price and due to short revisit periods, they offer a high degree of actuality. However, interpretation methods seem not to be adapted to this new type of images. The aim of our study is to develop a new method for semi-automatic building extraction with VHSR. The different steps performed to achieve our objective are each presented in a chapter. In the first chapter, the general context of our research is described with the definition of our objective. After a short historical review of urbanisation, we focus on urban growth and associated problems. In the following we discuss the possible contributions of geography to reduce these problems. After discussing concepts, theories and methodologies of geographical analysis in urban areas, we present existing general urban planning tools. Finally, we show the special interest of our study that is due to a growing need to integrate spatial information in these decision support tools. In the second chapter we verify the possibility of reaching our objective by analysing the technical characteristics of the images, the noise and the distortions which affect the images. Quality and interpretability of the studied image is analysed in order to show the capacity of these image to represent urban objects as close to reality as possible. The results confirm the potential of VHSR Imagery for urban objects analysis. The third chapter deal with the preliminary steps necessary for the elaboration of our method of building extraction. First, we evaluate the quality of the Sherbrooke Ikonos image

  13. Catalytic Hairpin Assembly Actuated DNA Nanotweezer for Logic Gate Building and Sensitive Enzyme-Free Biosensing of MicroRNAs.

    Science.gov (United States)

    Li, Dandan; Cheng, Wei; Li, Yujian; Xu, YongJie; Li, Xinmin; Yin, Yibing; Ju, Huangxian; Ding, Shijia

    2016-08-02

    A target-switched DNA nanotweezer is designed for AND logic gate operation and enzyme-free detection of microRNAs (miRNAs) by catalytic hairpin assembly (CHA) and proximity-dependent DNAzyme formation. The double crossover motif-based nanotweezer consists of an arched structure as the set strand for target inputs and two split G-rich DNAs at the termini of two arms for signal output. Upon a CHA, a small amount of binary target inputs can switch numerous open nanotweezers to a closed state, which leads to the formation of proximity-dependent DNAzyme in the presence of hemin to produce a highly sensitive biosensing system. The binary target inputs can be used for successful building of AND logic gate, which is validated by polyacrylamide gel electrophoresis, surface plasmon resonance and the biosensing signal. The developed biosensing system shows a linear response of the output chemiluminescence signal to input binary miRNAs with a detection limit of 30 fM. It can be used for miRNAs analysis in complex sample matrix. This system provides a simple and reusable platform for logic gate operation and enzyme-free, highly sensitive, and specific multianalysis of miRNAs.

  14. High-Sensitivity GaN Microchemical Sensors

    Science.gov (United States)

    Son, Kyung-ah; Yang, Baohua; Liao, Anna; Moon, Jeongsun; Prokopuk, Nicholas

    2009-01-01

    Systematic studies have been performed on the sensitivity of GaN HEMT (high electron mobility transistor) sensors using various gate electrode designs and operational parameters. The results here show that a higher sensitivity can be achieved with a larger W/L ratio (W = gate width, L = gate length) at a given D (D = source-drain distance), and multi-finger gate electrodes offer a higher sensitivity than a one-finger gate electrode. In terms of operating conditions, sensor sensitivity is strongly dependent on transconductance of the sensor. The highest sensitivity can be achieved at the gate voltage where the slope of the transconductance curve is the largest. This work provides critical information about how the gate electrode of a GaN HEMT, which has been identified as the most sensitive among GaN microsensors, needs to be designed, and what operation parameters should be used for high sensitivity detection.

  15. Building high-level features using large scale unsupervised learning

    CERN Document Server

    Le, Quoc V; Devin, Matthieu; Corrado, Greg; Chen, Kai; Ranzato, Marc'Aurelio; Dean, Jeff; Ng, Andrew Y

    2011-01-01

    We consider the problem of building detectors for high-level concepts using only unsupervised feature learning. For example, we would like to understand if it is possible to learn a face detector using only unlabeled images downloaded from the internet. To answer this question, we trained a simple feature learning algorithm on a large dataset of images (10 million images, each image is 200x200). The simulation is performed on a cluster of 1000 machines with fast network hardware for one week. Extensive experimental results reveal surprising evidence that such high-level concepts can indeed be learned using only unlabeled data and a simple learning algorithm.

  16. High Performance Homes That Use 50% Less Energy Than the DOE Building America Benchmark Building

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.

    2011-01-01

    This document describes lessons learned from designing, building, and monitoring five affordable, energy-efficient test houses in a single development in the Tennessee Valley Authority (TVA) service area. This work was done through a collaboration of Habitat for Humanity Loudon County, the US Department of Energy (DOE), TVA, and Oak Ridge National Laboratory (ORNL).The houses were designed by a team led by ORNL and were constructed by Habitat's volunteers in Lenoir City, Tennessee. ZEH5, a two-story house and the last of the five test houses to be built, provided an excellent model for conducting research on affordable high-performance houses. The impressively low energy bills for this house have generated considerable interest from builders and homeowners around the country who wanted a similar home design that could be adapted to different climates. Because a design developed without the project constraints of ZEH5 would have more appeal for the mass market, plans for two houses were developed from ZEH5: a one-story design (ZEH6) and a two-story design (ZEH7). This report focuses on ZEH6, identical to ZEH5 except that the geothermal heat pump is replaced with a SEER 16 air source unit (like that used in ZEH4). The report also contains plans for the ZEH6 house. ZEH5 and ZEH6 both use 50% less energy than the DOE Building America protocol for energyefficient buildings. ZEH5 is a 4 bedroom, 2.5 bath, 2632 ft2 house with a home energy rating system (HERS) index of 43, which qualifies it for federal energy-efficiency incentives (a HERS rating of 0 is a zero-energy house, and a conventional new house would have a HERS rating of 100). This report is intended to help builders and homeowners build similar high-performance houses. Detailed specifications for the envelope and the equipment used in ZEH5 are compared with the Building America Benchmark building, and detailed drawings, specifications, and lessons learned in the construction and analysis of data gleaned

  17. High-performance and high-sensitivity applications of graphene transistors with self-assembled monolayers.

    Science.gov (United States)

    Yeh, Chao-Hui; Kumar, Vinod; Moyano, David Ricardo; Wen, Shao-Hsuan; Parashar, Vyom; Hsiao, She-Hsin; Srivastava, Anchal; Saxena, Preeti S; Huang, Kun-Ping; Chang, Chien-Chung; Chiu, Po-Wen

    2016-03-15

    Charge impurities and polar molecules on the surface of dielectric substrates has long been a critical obstacle to using graphene for its niche applications that involve graphene's high mobility and high sensitivity nature. Self-assembled monolayers (SAMs) have been found to effectively reduce the impact of long-range scatterings induced by the external charges. Yet, demonstrations of scalable device applications using the SAMs technique remains missing due to the difficulties in the device fabrication arising from the strong surface tension of the modified dielectric environment. Here, we use patterned SAM arrays to build graphene electronic devices with transport channels confined on the modified areas. For high-mobility applications, both rigid and flexible radio-frequency graphene field-effect transistors (G-FETs) were demonstrated, with extrinsic cutoff frequency and maximum oscillation frequency enhanced by a factor of ~2 on SiO2/Si substrates. For high sensitivity applications, G-FETs were functionalized by monoclonal antibodies specific to cancer biomarker chondroitin sulfate proteoglycan 4, enabling its detection at a concentration of 0.01 fM, five orders of magnitude lower than that detectable by a conventional colorimetric assay. These devices can be very useful in the early diagnosis and monitoring of a malignant disease.

  18. High-albedo materials for reducing building cooling energy use

    Energy Technology Data Exchange (ETDEWEB)

    Taha, H.; Sailor, D.; Akbari, H.

    1992-01-01

    One simple and effective way to mitigate urban heat islands, i.e., the higher temperatures in cities compared to those of the surrounds, and their negative impacts on cooling energy consumption is to use high-albedo materials on major urban surfaces such as rooftops, streets, sidewalks, school yards, and the exposed surfaces of parking lots. High-albedo materials can save cooling energy use by directly reducing the heat gain through a building's envelope (direct effect) and also by lowering the urban air temperature in the neighborhood of the building (indirect effect). This project is an attempt to address high-albedo materials for buildings and to perform measurements of roof coatings. We search for existing methods and materials to implement fighter colors on major building and urban surfaces. Their cost effectiveness are examined and the possible related technical, maintenance, and environmental problems are identified. We develop a method for measuring albedo in the field by studying the instrumentation aspects of such measurements. The surface temperature impacts of various albedo/materials in the actual outdoor environment are studied by measuring the surface temperatures of a variety of materials tested on an actual roof. We also generate an albedo database for several urban surfaces to serve as a reference for future use. The results indicate that high-albedo materials can have a large impact on the surface temperature regime. On clear sunny days, when the solar noon surface temperatures of conventional roofing materials were about 40{degrees}C (72{degrees}F) warmer than air, the surface temperature of high-albedo coatings were only about 5{degrees}C warmer than air. In the morning and in the late afternoon, the high-albedo materials were as cool as the air itself. While conventional roofing materials warm up by an average 0.055{degrees}C/(W m{sup {minus}2}), the high-albedo surfaces warm up by an average 0.015{degrees}C/(W m{sup {minus}2}).

  19. Research on the classification result and accuracy of building windows in high resolution satellite images: take the typical rural buildings in Guangxi, China, as an example

    Science.gov (United States)

    Li, Baishou; Gao, Yujiu

    2015-12-01

    The information extracted from the high spatial resolution remote sensing images has become one of the important data sources of the GIS large scale spatial database updating. The realization of the building information monitoring using the high resolution remote sensing, building small scale information extracting and its quality analyzing has become an important precondition for the applying of the high-resolution satellite image information, because of the large amount of regional high spatial resolution satellite image data. In this paper, a clustering segmentation classification evaluation method for the high resolution satellite images of the typical rural buildings is proposed based on the traditional KMeans clustering algorithm. The factors of separability and building density were used for describing image classification characteristics of clustering window. The sensitivity of the factors influenced the clustering result was studied from the perspective of the separability between high image itself target and background spectrum. This study showed that the number of the sample contents is the important influencing factor to the clustering accuracy and performance, the pixel ratio of the objects in images and the separation factor can be used to determine the specific impact of cluster-window subsets on the clustering accuracy, and the count of window target pixels (Nw) does not alone affect clustering accuracy. The result can provide effective research reference for the quality assessment of the segmentation and classification of high spatial resolution remote sensing images.

  20. Triggers for a high sensitivity charm experiment

    Energy Technology Data Exchange (ETDEWEB)

    Christian, D.C.

    1994-07-01

    Any future charm experiment clearly should implement an E{sub T} trigger and a {mu} trigger. In order to reach the 10{sup 8} reconstructed charm level for hadronic final states, a high quality vertex trigger will almost certainly also be necessary. The best hope for the development of an offline quality vertex trigger lies in further development of the ideas of data-driven processing pioneered by the Nevis/U. Mass. group.

  1. Scalloped electrodes for highly sensitive electrical measurements

    DEFF Research Database (Denmark)

    Vazquez Rodriguez, Patricia; Dimaki, Maria; Svendsen, Winnie Edith

    2011-01-01

    In this work we introduce a novel out-of-plane electrode with pronounced scalloped surface and high aspect ratio for electrical recordings of brain tissue in vitro, with the aim to reduce significantly the impedance of the measuring system. The profile and height of the structures is tailored...... by means of silicon fabrication techniques that sharpen them progressively and in a controlled manner. We will show that the use of the scalloped area achieves a great decrease in impedance, which is very significant for a reduction of noise in electrical measurements. The measured impedance reflects...

  2. Building Momentum: National Trends and Prospects for High-Performance Green Buildings.

    Science.gov (United States)

    2003

    This report is an outgrowth of the Green Building Roundtable of the U.S. Senate Committee on Environment and Public Works held in conjunction with the U.S. Green Building Council on April 24, 2002. The roundtable brought together diverse interests to educate members of Congress on green building trends and generated discussion about the economic…

  3. Multipurpose High Sensitivity Radiation Detector: Terradex

    Energy Technology Data Exchange (ETDEWEB)

    Alpat, Behcet [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy)]. E-mail: behcet.alpat@pg.infn.it; Aisa, Damiano [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Bizzarri, Marco [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Blasko, Sandor [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Esposito, Gennaro [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Farnesini, Lucio [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Fiori, Emmanuel [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Papi, Andrea [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Postolache, Vasile [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Renzi, Francesca [Dipartimento di Fisica dell' Universita di Perugia and INFN Sezione di Perugia (Italy); Ionica, Romeo [Politecnica University of Bucarest, Splaiul Indipendentei, Bucharest (Romania); Manolescu, Florentina [Space Science Institute of Bucharest, Maugurele, Bucharest (Romania); Ozkorucuklu, Suat [Suleyman Demirel Universitesi, Isparta (Turkey); Denizli, Haluk [Abant Izzet Baysal Universitesi, Bolu (Turkey); Tapan, Ilhan [Uludag Universitesi, Bursa (Turkey); Ercan Pilicer [Uludag Universitesi, Bursa (Turkey); Egidi, Felice [SITE Technology, Carsoli (Italy); Moretti, Cesare [SITE Technology, Carsoli(AQ) (Italy); Dicola, Luca [SITE Technology, Carsoli(AQ) (Italy)

    2007-05-11

    Terradex project aims to realise an accurate and programmable multiparametric tool which will measure relevant physical quantities such as observation time, energy and type of all decay products of three naturally occurring decay chains of uranium and thorium series present in nature as well as the decay products of man-made radioactivity. The measurements described in this work are based on the performance tests of the first version of an instrument that is designed to provide high counting accuracy, by introducing self-triggering, delayed time-coincidence technique, of products of a given decay chain. In order to qualify the technique and to calibrate the Terradex, a {sup 222}Rn source is used. The continuous and accurate monitoring of radon concentration in air is realised by observing the alpha and beta particles produced by the decay of {sup 222}Rn and its daughters and tag each of them with a precise occurrence time. The validity of delayed coincident technique by using the state of the art electronics with application of novel data sampling and analysis methods are discussed. The flexibility of sampling protocols and the advantages of online calibration capability to achieve the highest level of precision in natural and man-made radiation measurements are also described.

  4. [The non-specific environmental syndromes MCS (Multiple Chemical Sensitivity), IEI (Idiopathic Environmental Intolerance) and SBS (Sick Building Syndrome)].

    Science.gov (United States)

    Csef, H

    1998-11-30

    This review starts with a clinical description of the most common unspecific environmental diseases, such as Multiple Chemical Sensitivities (MCS), Idiopathic Environmental Intolerances (IEI) and Sick Building Syndrome (SBS). These syndromes are very controversial discussed between scientific medicine and "clinical ecology". In addition, they have fundamental similarities to Chronic Fatigue Syndrome (CFS) and Fibromyalgia. Finally the spectrum of therapeutic approaches is discussed.

  5. Daylighting in linear atrium buildings at high latitudes

    Energy Technology Data Exchange (ETDEWEB)

    Matusiak, Barbara

    1998-12-31

    This thesis proposes new criteria for visual comfort based on knowledge of visual perception and a method for estimating the modelling ability of light by using inter-reflection calculations. Simplified calculations are presented for the daylight factor in linear building structures, using the projected solid angle principle, for uniform sky and for CIE overcast sky conditions. The calculations are compared with experimental results. Simple diagrams are created based on calculations of the mean daylight factor in rooms adjacent to a narrow street. These diagrams and presented formulas and tables can be used as a simple design tool. Daylighting strategies for linear atrium buildings at high latitudes are developed and examined. These strategies are divided into three groups: (1) the atrium space and facades as light conductor/reflector, (2) the glass roof as a light conductor, and (3) light reflectors on the neighbouring roof. The atrium space and facade strategies are subdivided into passive and active. The strategies connected to the glazed roof includes different configurations of glazing: horizontal, single pitched, double pitched, and the use of laser cut panels and prismatic panels in the glazed roof. The shapes of reflectors on the neighbouring roof are a flat reflector, a parabolic reflector and a parabolic concentrator. Strategies from all three groups are examined on a physical model of scale 1:20 in the artificial sky of mirror box type. Simulations with artificial sun have also been done. The results from model studies are compared with computer simulations. All the active daylighting systems designed for use in the atrium space or on the atrium facades have a huge potential for use in atrium buildings. From the strategies connected with the glazed roof the negatively sloped glass is found to be the best alternative for glazed roofs at high latitudes. Among the roof reflectors, the flat one performs best. 82 refs., 122 figs., 27 tabs.

  6. Design optimization of high pressure and high temperature piezoresistive pressure sensor for high sensitivity

    Science.gov (United States)

    Niu, Zhe; Zhao, Yulong; Tian, Bian

    2014-01-01

    This paper describes a design method for optimizing sensitivity of piezoresistive pressure sensor in high-pressure and high-temperature environment. In order to prove the method, a piezoresistive pressure sensor (HPTSS) is designed. With the purpose of increasing sensitivity and to improve the measurement range, the piezoresistive sensor adopts rectangular membrane and thick film structure. The configuration of piezoresistors is arranged according to the characteristic of the rectangular membrane. The structure and configuration of the sensor chip are analyzed theoretically and simulated by the finite element method. This design enables the sensor chip to operate in high pressure condition (such as 150 MPa) with a high sensitivity and accuracy. The silicon on insulator wafer is selected to guarantee the thermo stability of the sensor chip. In order to optimize the fabrication and improve the yield of production, an electric conduction step is devised. Series of experiments demonstrates a favorable linearity of 0.13% and a high accuracy of 0.48%. And the sensitivity of HTPSS is about six times as high as a conventional square-membrane sensor chip in the experiment. Compared with the square-membrane pressure sensor and current production, the strength of HPTTS lies in sensitivity and measurement. The performance of the HPTSS indicates that it could be an ideal candidate for high-pressure and high-temperature sensing in real application.

  7. Design optimization of high pressure and high temperature piezoresistive pressure sensor for high sensitivity.

    Science.gov (United States)

    Niu, Zhe; Zhao, Yulong; Tian, Bian

    2014-01-01

    This paper describes a design method for optimizing sensitivity of piezoresistive pressure sensor in high-pressure and high-temperature environment. In order to prove the method, a piezoresistive pressure sensor (HPTSS) is designed. With the purpose of increasing sensitivity and to improve the measurement range, the piezoresistive sensor adopts rectangular membrane and thick film structure. The configuration of piezoresistors is arranged according to the characteristic of the rectangular membrane. The structure and configuration of the sensor chip are analyzed theoretically and simulated by the finite element method. This design enables the sensor chip to operate in high pressure condition (such as 150 MPa) with a high sensitivity and accuracy. The silicon on insulator wafer is selected to guarantee the thermo stability of the sensor chip. In order to optimize the fabrication and improve the yield of production, an electric conduction step is devised. Series of experiments demonstrates a favorable linearity of 0.13% and a high accuracy of 0.48%. And the sensitivity of HTPSS is about six times as high as a conventional square-membrane sensor chip in the experiment. Compared with the square-membrane pressure sensor and current production, the strength of HPTTS lies in sensitivity and measurement. The performance of the HPTSS indicates that it could be an ideal candidate for high-pressure and high-temperature sensing in real application.

  8. A highly sensitive colorimetric and ratiometric sensor for fluoride ion

    Institute of Scientific and Technical Information of China (English)

    Zhao Wu Xu; Jin Tang; He Tian

    2008-01-01

    A new benzoimidazole-naphthalimide derivative 4 was synthesized and its photophysical properties were studied.This compound showed highly selectively and sensitive colorimetric and ratiometric sensing ability for fluoride anion.

  9. Building and measuring a high performance network architecture

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, William T.C.; Toole, Timothy; Fisher, Chuck; Dugan, Jon; Wheeler, David; Wing, William R; Nickless, William; Goddard, Gregory; Corbato, Steven; Love, E. Paul; Daspit, Paul; Edwards, Hal; Mercer, Linden; Koester, David; Decina, Basil; Dart, Eli; Paul Reisinger, Paul; Kurihara, Riki; Zekauskas, Matthew J; Plesset, Eric; Wulf, Julie; Luce, Douglas; Rogers, James; Duncan, Rex; Mauth, Jeffery

    2001-04-20

    Once a year, the SC conferences present a unique opportunity to create and build one of the most complex and highest performance networks in the world. At SC2000, large-scale and complex local and wide area networking connections were demonstrated, including large-scale distributed applications running on different architectures. This project was designed to use the unique opportunity presented at SC2000 to create a testbed network environment and then use that network to demonstrate and evaluate high performance computational and communication applications. This testbed was designed to incorporate many interoperable systems and services and was designed for measurement from the very beginning. The end results were key insights into how to use novel, high performance networking technologies and to accumulate measurements that will give insights into the networks of the future.

  10. VERTICAL LINEAR PROJECT SCHEDULING FOR HIGH-RISE BUILDINGS

    Directory of Open Access Journals (Sweden)

    İlker ÖZDEMİR

    1999-02-01

    Full Text Available In this paper, an application to high-rise buildings of VPM (Vertical Production Method and an example will be given which is composition of two distinct and preferable methods are CPM (Critical Path Method that is prefering against traditional Bar-Charts or schedules especially in big and costly investments and LOB (Line of Balance technique that is suitable for using in linear project planning. Thus, it could be expected that to show the way of the method to designer and manufacturer about subjects which are activity, priority and sequencing of high-rise project, speeds of activity and construction, completion times, to add or take out some terms to schedule at the state of project changing.

  11. Energy-Performance-Based Design-Build Process: Strategies for Procuring High-Performance Buildings on Typical Construction Budgets: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Scheib, J.; Pless, S.; Torcellini, P.

    2014-08-01

    NREL experienced a significant increase in employees and facilities on our 327-acre main campus in Golden, Colorado over the past five years. To support this growth, researchers developed and demonstrated a new building acquisition method that successfully integrates energy efficiency requirements into the design-build requests for proposals and contracts. We piloted this energy performance based design-build process with our first new construction project in 2008. We have since replicated and evolved the process for large office buildings, a smart grid research laboratory, a supercomputer, a parking structure, and a cafeteria. Each project incorporated aggressive efficiency strategies using contractual energy use requirements in the design-build contracts, all on typical construction budgets. We have found that when energy efficiency is a core project requirement as defined at the beginning of a project, innovative design-build teams can integrate the most cost effective and high performance efficiency strategies on typical construction budgets. When the design-build contract includes measurable energy requirements and is set up to incentivize design-build teams to focus on achieving high performance in actual operations, owners can now expect their facilities to perform. As NREL completed the new construction in 2013, we have documented our best practices in training materials and a how-to guide so that other owners and owner's representatives can replicate our successes and learn from our experiences in attaining market viable, world-class energy performance in the built environment.

  12. Sensitivity of calcification to thermal stress varies among genera of massive reef-building corals.

    Directory of Open Access Journals (Sweden)

    Juan P Carricart-Ganivet

    Full Text Available Reductions in calcification in reef-building corals occur when thermal conditions are suboptimal, but it is unclear how they vary between genera in response to the same thermal stress event. Using densitometry techniques, we investigate reductions in the calcification rate of massive Porites spp. from the Great Barrier Reef (GBR, and P. astreoides, Montastraea faveolata, and M. franksi from the Mesoamerican Barrier Reef (MBR, and correlate them to thermal stress associated with ocean warming. Results show that Porites spp. are more sensitive to increasing temperature than Montastraea, with calcification rates decreasing by 0.40 g cm(-2 year(-1 in Porites spp. and 0.12 g cm(-2 year(-1 in Montastraea spp. for each 1°C increase. Under similar warming trends, the predicted calcification rates at 2100 are close to zero in Porites spp. and reduced by 40% in Montastraea spp. However, these predictions do not account for ocean acidification. Although yearly mean aragonite saturation (Ω(ar at MBR sites has recently decreased, only P. astreoides at Chinchorro showed a reduction in calcification. In corals at the other sites calcification did not change, indicating there was no widespread effect of Ω(ar changes on coral calcification rate in the MBR. Even in the absence of ocean acidification, differential reductions in calcification between Porites spp. and Montastraea spp. associated with warming might be expected to have significant ecological repercussions. For instance, Porites spp. invest increased calcification in extension, and under warming scenarios it may reduce their ability to compete for space. As a consequence, shifts in taxonomic composition would be expected in Indo-Pacific reefs with uncertain repercussions for biodiversity. By contrast, Montastraea spp. use their increased calcification resources to construct denser skeletons. Reductions in calcification would therefore make them more susceptible to both physical and biological

  13. Energy-Efficient Office Buildings at High Latitudes

    Energy Technology Data Exchange (ETDEWEB)

    Lerum, V.

    1996-12-31

    This doctoral thesis describes a method for energy efficient office building design at high latitudes and cold climates. The method combines daylighting, passive solar heating, solar protection, and ventilative cooling. The thesis focuses on optimal design of an equatorial-facing fenestration system. A spreadsheet framework linking existing simplified methods is used. The daylight analysis uses location specific data on frequency distribution of diffuse daylight on vertical surfaces to estimate energy savings from optimal window and room configurations in combination with a daylight-responsive electric lighting system. The passive solar heating analysis is a generalization of a solar load ratio method adapted to cold climates by combining it with the Norwegian standard NS3031 for winter months when the solar savings fraction is negative. The emphasis is on very high computational efficiency to permit rapid and comprehensive examination of a large number of options early in design. The procedure is illustrated for a location in Trondheim, Norway, testing the relative significance of various design improvement options relative to a base case. The method is also tested for two other locations in Norway, at latitudes 58 and 70 degrees North. The band of latitudes between these limits covers cities in Alaska, Canada, Greenland, Iceland, Scandinavia, Finland, Russia, and Northern Japan. A comprehensive study of the ``whole building approach`` shows the impact of integrated daylighting and low-energy design strategies. In general, consumption of lighting electricity may be reduced by 50-80%, even at extremely high latitudes. The reduced internal heat from electric lights is replaced by passive solar heating. 113 refs., 85 figs., 25 tabs.

  14. `Slow Science': Building scientific concepts in physics in high school

    Science.gov (United States)

    Bigozzi, Lucia; Tarchi, Christian; Falsini, Paola; Fiorentini, Carlo

    2014-09-01

    In this study, a progressive-learning approach to physics, based on knowledge-building pedagogy, was compared to a content-centered approach in which explanations, experiments, and discussions are centered on the transmission of knowledge. Forty-six students attending the first year of high school participated in this study over a whole school year. Students' knowledge and mastery of physics concepts were assessed through questionnaires containing both open-ended and multiple-choice questions. Overall, the 'progressive-learning' group outperformed the content-centered group. Results are discussed in relation to the theoretical background and the experimental teacher's diary of classroom activities. The main conclusion achieved by this study is that the teaching of physics should be slow, cyclic, and developmentally appropriate for the context.

  15. Low Temperature Heating and High Temperature Cooling in Buildings

    DEFF Research Database (Denmark)

    Kazanci, Ongun Berk

    , a single-family house designed for plus-energy targets and equipped with a radiant water-based floor heating and cooling system was studied by means of full-scale measurements, dynamic building simulations and thermodynamic evaluation tools. Thermal indoor environment and energy performance of the house...... performance of heating and cooling systems for achieving the same thermal indoor environment. The results show that it is crucial to minimize the heating and cooling demands in the design phase since these demands determine the terminal units and heat sources and sinks that could be used. Low temperature...... heating and high temperature cooling systems (a radiant water-based floor heating and cooling system in this study) proved to be superior to compared systems, evaluated with different system analysis tools; energy, exergy, and entransy. Radiant systems should be coupled to appropriate heating and cooling...

  16. Transplantation in highly HLA-sensitized patients: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Kim IK

    2014-09-01

    Full Text Available Irene K Kim, Ashley Vo, Stanley C Jordan Transplant Immunotherapy Program, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA Abstract: Despite better understanding of the impact of development of the human leukocyte antigen (HLA antibody and numerous advancements in immunosuppressive therapy, the ability to successfully transplant highly sensitized patients remains a significant challenge. As the percentage of the waiting list becomes increasingly populated with highly sensitized patients, there is a growing demand for effective strategies to manage these patients. Over the past 20 years, desensitization therapies have been modified and developed, and are mainly utilized at transplant centers that have developed expertise. In addition, recognition that the highly sensitized patient population is disadvantaged on the transplant waiting list has led to recent changes in national kidney allocation policy. Furthermore, creative strategies, such as enrollment of sensitized patients into paired kidney exchange programs, have been developed to find compatible matches for these patients. The goal of this article is to address some of the specific challenges related to transplanting the highly sensitized patient at a high-volume transplant center with experience in desensitization and to review established and emerging solutions to help this patient population. Keywords: human leukocyte antigen, antibodies, desensitization, high-dose intravenous immunoglobulin, rituximab

  17. Mutagen sensitivity has high heritability: evidence from a twin study.

    Science.gov (United States)

    Wu, Xifeng; Spitz, Margaret R; Amos, Christopher I; Lin, Jie; Shao, Lina; Gu, Jian; de Andrade, Mariza; Benowitz, Neal L; Shields, Peter G; Swan, Gary E

    2006-06-15

    Despite numerous studies showing that mutagen sensitivity is a cancer predisposition factor, the heritability of mutagen sensitivity has not been clearly established. In this report, we used a classic twin study design to examine the role of genetic and environmental factors on the mutagen sensitivity phenotype. Mutagen sensitivity was measured in peripheral blood lymphocytes from 460 individuals [148 pairs of monozygotic (MZ) twins, 57 pairs of dizygotic (DZ) twins, and 50 siblings]. The intraclass correlation coefficients were all significantly higher in MZ twins than in dizygotes (DZ pairs and MZ-sibling pairs combined) for sensitivity to four different mutagen challenges. Applying biometric genetic modeling, we calculated a genetic heritability of 40.7%, 48.0%, 62.5%, and 58.8% for bleomycin, benzo[a]pyrene diol epoxide, gamma-radiation, and 4-nitroquinoline-1-oxide sensitivity, respectively. This study provides the strongest and most direct evidence that mutagen sensitivity is highly heritable, thereby validating the use of mutagen sensitivity as a cancer susceptibility factor.

  18. Tailored high-resolution numerical weather forecasts for energy efficient predictive building control

    Science.gov (United States)

    Stauch, V. J.; Gwerder, M.; Gyalistras, D.; Oldewurtel, F.; Schubiger, F.; Steiner, P.

    2010-09-01

    The high proportion of the total primary energy consumption by buildings has increased the public interest in the optimisation of buildings' operation and is also driving the development of novel control approaches for the indoor climate. In this context, the use of weather forecasts presents an interesting and - thanks to advances in information and predictive control technologies and the continuous improvement of numerical weather prediction (NWP) models - an increasingly attractive option for improved building control. Within the research project OptiControl (www.opticontrol.ethz.ch) predictive control strategies for a wide range of buildings, heating, ventilation and air conditioning (HVAC) systems, and representative locations in Europe are being investigated with the aid of newly developed modelling and simulation tools. Grid point predictions for radiation, temperature and humidity of the high-resolution limited area NWP model COSMO-7 (see www.cosmo-model.org) and local measurements are used as disturbances and inputs into the building system. The control task considered consists in minimizing energy consumption whilst maintaining occupant comfort. In this presentation, we use the simulation-based OptiControl methodology to investigate the impact of COSMO-7 forecasts on the performance of predictive building control and the resulting energy savings. For this, we have selected building cases that were shown to benefit from a prediction horizon of up to 3 days and therefore, are particularly suitable for the use of numerical weather forecasts. We show that the controller performance is sensitive to the quality of the weather predictions, most importantly of the incident radiation on differently oriented façades. However, radiation is characterised by a high temporal and spatial variability in part caused by small scale and fast changing cloud formation and dissolution processes being only partially represented in the COSMO-7 grid point predictions. On the

  19. Achieving sensitive, high-resolution laser spectroscopy at CRIS

    Energy Technology Data Exchange (ETDEWEB)

    Groote, R. P. de [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Lynch, K. M., E-mail: kara.marie.lynch@cern.ch [EP Department, CERN, ISOLDE (Switzerland); Wilkins, S. G. [The University of Manchester, School of Physics and Astronomy (United Kingdom); Collaboration: the CRIS collaboration

    2017-11-15

    The Collinear Resonance Ionization Spectroscopy (CRIS) experiment, located at the ISOLDE facility, has recently performed high-resolution laser spectroscopy, with linewidths down to 20 MHz. In this article, we present the modifications to the beam line and the newly-installed laser systems that have made sensitive, high-resolution measurements possible. Highlights of recent experimental campaigns are presented.

  20. A highly sensitive optical detector for use in deep underwater.

    Science.gov (United States)

    Hanada, H.; Hayashino, T.; Ito, M.; Iwasaki, A.; Kawamorita, K.; Kawamoto, H.; Matsumoto, T.; Narita, S.; Takayama, T.; Tanaka, S.; Yamaguchi, A.; Aoki, T.; Mitsui, K.; Ohashi, Y.; Okada, A.; Fukawa, M.; Uehara, S.; Bolesta, J. W.; Gorham, P. W.; Kondo, S.; Learned, J. G.; Matsuno, S.; Mignard, M.; Mitiguy, R.; O'Connor, D. J.; Peterson, V. Z.; Roberts, A.; Rosen, M.; Stenger, V. J.; Takemori, D.; Wilkins, G.; Grieder, P. K. F.; Minkowski, P.; Kitamura, T.; Camerini, U.; Grogan, W.; Jaworski, M.; March, R.; Narita, T.; Nicklaus, D.

    1998-05-01

    The authors have developed an optical detector module for use in deep underwater experiments that will search for high-energy neutrinos from cosmic rays and astronomical sources. This module is sensitive to single photons, is operable under high pressure, functions automatically and is remotely controlled.

  1. Building-Wide, Adaptive Energy Management Systems for High-Performance Buildings: Final CRADA Report

    Energy Technology Data Exchange (ETDEWEB)

    Zavala, Victor M. [Argonne National Lab. (ANL), Argonne, IL (United States). Mathematics and Computer Science

    2016-10-27

    Development and field demonstration of the minimum ratio policy for occupancy-driven, predictive control of outdoor air ventilation. Technology transfer of Argonne’s methods for occupancy estimation and forecasting and for M&V to BuildingIQ for their deployment. Selection of CO2 sensing as the currently best-available technology for occupancy-driven controls. Accelerated restart capability for the commercial BuildingIQ system using horizon shifting strategies applied to receding horizon optimal control problems. Empirical-based evidence of 30% chilled water energy savings and 22% total HVAC energy savings achievable with the BuildingIQ system operating in the APS Office Building on-site at Argonne.

  2. Research of High Sensitivity Uncooled Infrared Detector Array

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Pingchuan [Huazhong University of Science and Technology, Wuhan 430074 (China); Zhang, Bo, E-mail: redmoon123456@126.com, E-mail: lhzyzb@126.com [Luohe Vocational Technology College, Luohe 462002 (China)

    2011-02-01

    The infrared thermal imaging technology has been widely used in military and civilian fields and the field of the infrared detection and infrared thermal imaging technology has been of concern for a long time. On infrared thermal imaging, its core components for the infrared focal plane arrays, how to develop a high sensitivity of the multi-focal plane infrared detector is a key issue. Although the Common focal plane array of quantum has high sensitivity, but it requires low temperature cooling work environment and led to complexity and high cost, difficult to compact. Conventional uncooled infrared focal plane array is contrast to the quantum focal plane arrays. Therefore, this article preceded by the uncooled infrared detector array to improve the wide temperature sensitivity in examining the feasibility PMN composite film, materials composition, structure design and preparation process technology.

  3. High Performance Building Facade Solutions - PIER Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eleanor; Selkowitz, Stephen

    2009-12-31

    Building facades directly influence heating and cooling loads and indirectly influence lighting loads when daylighting is considered, and are therefore a major determinant of annual energy use and peak electric demand. Facades also significantly influence occupant comfort and satisfaction, making the design optimization challenge more complex than many other building systems.This work focused on addressing significant near-term opportunities to reduce energy use in California commercial building stock by a) targeting voluntary, design-based opportunities derived from the use of better design guidelines and tools, and b) developing and deploying more efficient glazings, shading systems, daylighting systems, facade systems and integrated controls. This two-year project, supported by the California Energy Commission PIER program and the US Department of Energy, initiated a collaborative effort between The Lawrence Berkeley National Laboratory (LBNL) and major stakeholders in the facades industry to develop, evaluate, and accelerate market deployment of emerging, high-performance, integrated facade solutions. The LBNL Windows Testbed Facility acted as the primary catalyst and mediator on both sides of the building industry supply-user business transaction by a) aiding component suppliers to create and optimize cost effective, integrated systems that work, and b) demonstrating and verifying to the owner, designer, and specifier community that these integrated systems reliably deliver required energy performance. An industry consortium was initiated amongst approximately seventy disparate stakeholders, who unlike the HVAC or lighting industry, has no single representative, multi-disciplinary body or organized means of communicating and collaborating. The consortium provided guidance on the project and more importantly, began to mutually work out and agree on the goals, criteria, and pathways needed to attain the ambitious net zero energy goals defined by California and

  4. Highly sensitive optical sensor system for blood leakage detection

    Science.gov (United States)

    Ueda, Masahiro; Ishikawa, Kazuhiko; Jie, Chen; Sanae, Mizuno; Touma, Yasunori

    A highly sensitive method for the detection of blood leakage has been developed, and a practical sensor system for blood concentration measurement has been constructed. The present method is based on the attenuation of laser light by blood cells. The effects of the fluctuations of the incident laser light power are eliminated by normalizing the attenuated light intensity by the incident light intensity. A part of the incident laser light is reflected by a beam splitter mounted at the entrance of the test cell, of which the power is measured to provide base data for normalization. The optical path is extended to enhance sensitivity by using a pair of side mirrors. This multi-reflection method is very effective to increase sensitivity; the maximum sensitivity obtained for blood concentration is about 4 X 10 -6 by volume, which is significantly higher than that of the conventional sensors.

  5. High-Performance Green Building: Towards a Conceptual Framework

    CSIR Research Space (South Africa)

    Van Wyk, Llewellyn

    2016-10-01

    Full Text Available , biomimicry, the Natural Step, eco-efficiency, ecological economics, biophilia, and the precautionary principle” (2013:7). It has been argued (Gross 1996) that building performance is not a well understood or articulated concept in the building and property...

  6. Scalable photonic crystal chips for high sensitivity protein detection.

    Science.gov (United States)

    Liang, Feng; Clarke, Nigel; Patel, Parth; Loncar, Marko; Quan, Qimin

    2013-12-30

    Scalable microfabrication technology has enabled semiconductor and microelectronics industries, among other fields. Meanwhile, rapid and sensitive bio-molecule detection is increasingly important for drug discovery and biomedical diagnostics. In this work, we designed and demonstrated that photonic crystal sensor chips have high sensitivity for protein detection and can be mass-produced with scalable deep-UV lithography. We demonstrated label-free detection of carcinoembryonic antigen from pg/mL to μg/mL, with high quality factor photonic crystal nanobeam cavities.

  7. Experimental Investigation on a Highly Sensitive Atomic Magnetometer

    Institute of Scientific and Technical Information of China (English)

    LI Shu-Guang; XU Yun-Fei; WANG Zhao-Ying; LIU Yun-Xian; LIN Qiang

    2009-01-01

    A highly sensitive all-optical atomic magnetometer based on the magnetooptical effect which uses the advanced technique of single laser beam detection is reported and demonstrated experimentally.A sensitivityof 0.5 pT/Hz1/2 is obtained by analyzing the magnetic noise spectrum,which exceeds that of most traditional magnetometers.This kind of atomic magnetometer is very compact,has a low power consumption,and has a high theoretical sensitivity limit,which make it suitable for many applications.

  8. High-sensitivity, high-speed continuous imaging system

    Science.gov (United States)

    Watson, Scott A; Bender, III, Howard A

    2014-11-18

    A continuous imaging system for recording low levels of light typically extending over small distances with high-frame rates and with a large number of frames is described. Photodiode pixels disposed in an array having a chosen geometry, each pixel having a dedicated amplifier, analog-to-digital convertor, and memory, provide parallel operation of the system. When combined with a plurality of scintillators responsive to a selected source of radiation, in a scintillator array, the light from each scintillator being directed to a single corresponding photodiode in close proximity or lens-coupled thereto, embodiments of the present imaging system may provide images of x-ray, gamma ray, proton, and neutron sources with high efficiency.

  9. Large pi-aromatic molecules as potential sensitizers for highly efficient dye-sensitized solar cells.

    Science.gov (United States)

    Imahori, Hiroshi; Umeyama, Tomokazu; Ito, Seigo

    2009-11-17

    Recently, dye-sensitized solar cells have attracted much attention relevant to global environmental issues. Thus far, ruthenium(II) bipyridyl complexes have proven to be the most efficient TiO(2) sensitizers in dye-sensitized solar cells. However, a gradual increment in the highest power conversion efficiency has been recognized in the past decade. More importantly, considering that ruthenium is a rare metal, novel dyes without metal or using inexpensive metal are desirable for highly efficient dye-sensitized solar cells. Large pi-aromatic molecules, such as porphyrins, phthalocyanines, and perylenes, are important classes of potential sensitizers for highly efficient dye-sensitized solar cells, owing to their photostability and high light-harvesting capabilities that can allow applications in thinner, low-cost dye-sensitized solar cells. Porphyrins possess an intense Soret band at 400 nm and moderate Q bands at 600 nm. Nevertheless, the poor light-harvesting properties relative to the ruthenium complexes have limited the cell performance of porphyrin-sensitized TiO(2) cells. Elongation of the pi conjugation and loss of symmetry in porphyrins cause broadening and a red shift of the absorption bands together with an increasing intensity of the Q bands relative to that of the Soret band. On the basis of the strategy, the cell performance of porphyrin-sensitized solar cells has been improved intensively by the enhanced light absorption. Actually, some push-pull-type porphyrins have disclosed a remarkably high power conversion efficiency (6-7%) that was close to that of the ruthenium complexes. Phthalocyanines exhibit strong absorption around 300 and 700 nm and redox features that are similar to porphyrins. Moreover, phthalocyanines are transparent over a large region of the visible spectrum, thereby enabling the possibility of using them as "photovoltaic windows". However, the cell performance was poor, owing to strong aggregation and lack of directionality in the

  10. Commissioning: A Highly Cost-Effective Building Energy Management Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Evan

    2011-01-06

    Quality assurance and optimization are essential elements of any serious technological endeavor, including efforts to improve energy efficiency. Commissioning is an important tool in this respect. The aim of commissioning new buildings is to ensure that they deliver-if not exceed-the performance and energy savings promised by their design. When applied to existing buildings, one-time or repeated commissioning (often called retrocommissioning) identifies the almost inevitable drift in energy performance and puts the building back on course, often surpassing the original design intent. In both contexts, commissioning is a systematic, forensic approach to improving performance, rather than a discrete technology.

  11. Portable High Sensitivity and High Resolution Sensor to Determine Oxygen Purity Levels Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this Phase I STTR project is to develop a highly sensitive oxygen (O2) sensor, with high accuracy and precision, to determine purity levels of high...

  12. Aluminum nano-cantilevers for high sensitivity mass sensors

    DEFF Research Database (Denmark)

    Davis, Zachary James; Boisen, Anja

    2005-01-01

    We have fabricated Al nano-cantilevers using a very simple one mask contact UV lithography technique with lateral dimensions under 500 nm and vertical dimensions of approximately 100 nm. These devices are demonstrated as highly sensitive mass sensors by measuring their dynamic properties. Further...

  13. Highly Sensitive AMS Measurement of 53Mn at CIAE

    Institute of Scientific and Technical Information of China (English)

    DONG; Ke-jun; HU; Hao; LIU; Guang-shan; HE; Ming; LI; Zhen-yu; DOU; Liang; XIE; Lin-bo; LIU; Jian-cheng; WANG; Xiang-gao; SHEN; Hong-tao; LIN; De-yu; ZHENG; Guo-wen; WANG; Xiao-bo; LI; Heng; LI; Chao-li; WU; Shao-yong; YOU; Qu-bo; JIN; Chun-sheng; CHEN; Zhi-gang; YUAN; Jian; JIANG; Shan

    2013-01-01

    Methods for highly sensitive AMS measurement of 53Mn were explored by extracting different Mn-containing molecular ions in ion source and using different chemical forms of sample materials.Preliminary results indicate that a method for AMS measurement of 53Mn has been established and a-155355

  14. Sensitivity Study of Strapdown Inertial Sensors in High Performance Applications

    Science.gov (United States)

    1980-12-01

    system error varied with a change in heading 7K. ( xii 1 SENSITIVITY STUDY OF STRAPDOWN INERTIAL SENSORS IN HIGH PERFORMANCE APPLICATIONS I. Introduction...given in Tabla 10. 23 State Meaning o Basic Altitude Damped INS x(1) Error in East Longitude 5.7735 x 1O Ŗ arc min x(2) Error in North Latitude

  15. [Burner head with high sensitivity in atomic absorption spectroscopy].

    Science.gov (United States)

    Feng, X; Yang, Y

    1998-12-01

    This paper presents a burner head with gas-sample separate entrance and double access, which is used for atomic absorption spectroscopy. According to comparison and detection, the device can improve sensitivity by a factor of 1 to 5. In the meantime it has properties of high stability and resistance to interference.

  16. Microelectromechanical Resonant Accelerometer Designed with a High Sensitivity

    Science.gov (United States)

    Zhang, Jing; Su, Yan; Shi, Qin; Qiu, An-Ping

    2015-01-01

    This paper describes the design and experimental evaluation of a silicon micro-machined resonant accelerometer (SMRA). This type of accelerometer works on the principle that a proof mass under acceleration applies force to two double-ended tuning fork (DETF) resonators, and the frequency output of two DETFs exhibits a differential shift. The dies of an SMRA are fabricated using silicon-on-insulator (SOI) processing and wafer-level vacuum packaging. This research aims to design a high-sensitivity SMRA because a high sensitivity allows for the acceleration signal to be easily demodulated by frequency counting techniques and decreases the noise level. This study applies the energy-consumed concept and the Nelder-Mead algorithm in the SMRA to address the design issues and further increase its sensitivity. Using this novel method, the sensitivity of the SMRA has been increased by 66.1%, which attributes to both the re-designed DETF and the reduced energy loss on the micro-lever. The results of both the closed-form and finite-element analyses are described and are in agreement with one another. A resonant frequency of approximately 22 kHz, a frequency sensitivity of over 250 Hz per g, a one-hour bias stability of 55 μg, a bias repeatability (1σ) of 48 μg and the bias-instability of 4.8 μg have been achieved. PMID:26633425

  17. Microelectromechanical Resonant Accelerometer Designed with a High Sensitivity

    Directory of Open Access Journals (Sweden)

    Jing Zhang

    2015-12-01

    Full Text Available This paper describes the design and experimental evaluation of a silicon micro-machined resonant accelerometer (SMRA. This type of accelerometer works on the principle that a proof mass under acceleration applies force to two double-ended tuning fork (DETF resonators, and the frequency output of two DETFs exhibits a differential shift. The dies of an SMRA are fabricated using silicon-on-insulator (SOI processing and wafer-level vacuum packaging. This research aims to design a high-sensitivity SMRA because a high sensitivity allows for the acceleration signal to be easily demodulated by frequency counting techniques and decreases the noise level. This study applies the energy-consumed concept and the Nelder-Mead algorithm in the SMRA to address the design issues and further increase its sensitivity. Using this novel method, the sensitivity of the SMRA has been increased by 66.1%, which attributes to both the re-designed DETF and the reduced energy loss on the micro-lever. The results of both the closed-form and finite-element analyses are described and are in agreement with one another. A resonant frequency of approximately 22 kHz, a frequency sensitivity of over 250 Hz per g, a one-hour bias stability of 55 μg, a bias repeatability (1σ of 48 μg and the bias-instability of 4.8 μg have been achieved.

  18. Highlighting High Performance Buildings: 4 Times Square, New York City

    Energy Technology Data Exchange (ETDEWEB)

    None

    2001-11-01

    4 Times Square is a 48-story environmentally responsible building in New York City and is the first project of its size to adopt standards for energy efficiency, indoor ecology, sustainable materials.

  19. Highly sensitive detection using microring resonator and nanopores

    Science.gov (United States)

    Bougot-Robin, K.; Hoste, J. W.; Le Thomas, N.; Bienstman, P.; Edel, J. B.

    2016-04-01

    One of the most significant challenges facing physical and biological scientists is the accurate detection and identification of single molecules in free-solution environments. The ability to perform such sensitive and selective measurements opens new avenues for a large number of applications in biological, medical and chemical analysis, where small sample volumes and low analyte concentrations are the norm. Access to information at the single or few molecules scale is rendered possible by a fine combination of recent advances in technologies. We propose a novel detection method that combines highly sensitive label-free resonant sensing obtained with high-Q microcavities and position control in nanoscale pores (nanopores). In addition to be label-free and highly sensitive, our technique is immobilization free and does not rely on surface biochemistry to bind probes on a chip. This is a significant advantage, both in term of biology uncertainties and fewer biological preparation steps. Through combination of high-Q photonic structures with translocation through nanopore at the end of a pipette, or through a solid-state membrane, we believe significant advances can be achieved in the field of biosensing. Silicon microrings are highly advantageous in term of sensitivity, multiplexing, and microfabrication and are chosen for this study. In term of nanopores, we both consider nanopore at the end of a nanopipette, with the pore being approach from the pipette with nanoprecise mechanical control. Alternatively, solid state nanopores can be fabricated through a membrane, supporting the ring. Both configuration are discussed in this paper, in term of implementation and sensitivity.

  20. Highly Mass-Sensitive Thin Film Plate Acoustic Resonators (FPAR)

    Science.gov (United States)

    Arapan, Lilia; Alexieva, Gergana; Avramov, Ivan D.; Radeva, Ekaterina; Strashilov, Vesseline; Katardjiev, Ilia; Yantchev, Ventsislav

    2011-01-01

    The mass sensitivity of thin aluminum nitride (AlN) film S0 Lamb wave resonators is theoretically and experimentally studied. Theoretical predictions based on modal and finite elements method analysis are experimentally verified. Here, two-port 888 MHz synchronous FPARs are micromachined and subsequently coated with hexamethyl-disiloxane(HMDSO)-plasma-polymerized thin films of various thicknesses. Systematic data on frequency shift and insertion loss versus film thickness are presented. FPARs demonstrate high mass-loading sensitivity as well as good tolerance towards the HMDSO viscous losses. Initial measurements in gas phase environment are further presented. PMID:22163994

  1. Highly mass-sensitive thin film plate acoustic resonators (FPAR).

    Science.gov (United States)

    Arapan, Lilia; Alexieva, Gergana; Avramov, Ivan D; Radeva, Ekaterina; Strashilov, Vesseline; Katardjiev, Ilia; Yantchev, Ventsislav

    2011-01-01

    The mass sensitivity of thin aluminum nitride (AlN) film S0 Lamb wave resonators is theoretically and experimentally studied. Theoretical predictions based on modal and finite elements method analysis are experimentally verified. Here, two-port 888 MHz synchronous FPARs are micromachined and subsequently coated with hexamethyl-disiloxane(HMDSO)-plasma-polymerized thin films of various thicknesses. Systematic data on frequency shift and insertion loss versus film thickness are presented. FPARs demonstrate high mass-loading sensitivity as well as good tolerance towards the HMDSO viscous losses. Initial measurements in gas phase environment are further presented.

  2. Design and Fabrication of High Sensitive Piezoresistive MEMS Accelerometer

    Directory of Open Access Journals (Sweden)

    JOSHI A.B

    2008-04-01

    Full Text Available This paper addresses the design and fabrication of high sensitive single axis piezoresistive micro-accelerometer for 50 g application. MEMS based accelerometer structure comprise of flexure fixed at one end and having attached proof mass at other end. This structure is designed and simulated using Coventorware. The simulation results show the sensitivity of 4mV/g. The structure is fabricated in N type silicon (100 substrate using Silicon bulk micromachining. This paper also discuses the use of PECVD Si3N4 layer as a masking material for silicon micromachining and process flow for accelerometer.

  3. Cardiac troponins and high-sensitivity cardiac troponin assays.

    Science.gov (United States)

    Conrad, Michael J; Jarolim, Petr

    2014-03-01

    Measurement of circulating cardiac troponins I and T has become integral to the diagnosis of myocardial infarction. This article discusses the structure and function of the troponin complex and the release of cardiac troponin molecules from the injured cardiomyocyte into the circulation. An overview of current cardiac troponin assays and their classification according to sensitivity is presented. The diagnostic criteria, role, and usefulness of cardiac troponin for myocardial infarction are discussed. In addition, several examples are given of the usefulness of high-sensitivity cardiac troponin assays for short-term and long-term prediction of adverse events.

  4. Highly Mass-Sensitive Thin Film Plate Acoustic Resonators (FPAR

    Directory of Open Access Journals (Sweden)

    Ventsislav Yantchev

    2011-07-01

    Full Text Available The mass sensitivity of thin aluminum nitride (AlN film S0 Lamb wave resonators is theoretically and experimentally studied. Theoretical predictions based on modal and finite elements method analysis are experimentally verified. Here, two-port 888 MHz synchronous FPARs are micromachined and subsequently coated with hexamethyl-disiloxane(HMDSO-plasma-polymerized thin films of various thicknesses. Systematic data on frequency shift and insertion loss versus film thickness are presented. FPARs demonstrate high mass-loading sensitivity as well as good tolerance towards the HMDSO viscous losses. Initial measurements in gas phase environment are further presented.

  5. High Sensitivity Very Low Frequency Receiver for Earthquake Data Acquisition.

    Science.gov (United States)

    Munir, A.; Najmurrokhman, A.

    2017-03-01

    high sensitivity very low frequency (VLF) receiver is developed based on AD744 monolithic operational amplifier (Op-Amp) for earthquake data acquisition. In research related natural phenomena such as atmospheric noise, lightning and earthquake, a VLF receiver particularly with high sensitivity is utterly required due to the low power of VLF wave signals received by the antenna. The developed receiver is intended to have high sensitivity reception for the signals in frequency range of 10-30kHz allocated for earthquake observation. The VLF receiver which is portably designed is also equipped with an output port connectable to the soundcard of personal computer for further data acquisition. After obtaining the optimum design, the hardware realization is implemented on a printed circuit board (PCB) for experimental characterization. It shows that the sensitivity of realized VLF receiver is almost linear in the predefined frequency range for the input signals lower than -12dBm and to be quadratic for the higher level input signals.

  6. High Sensitivity Polymer Optical Fiber-Bragg-Grating-Based Accelerometer

    DEFF Research Database (Denmark)

    Stefani, Alessio; Andresen, Søren; Yuan, Wu

    2012-01-01

    We report on the fabrication and characterization of the first accelerometer based on a polymer optical fiber Bragg grating (FBG) for operation at both 850 and 1550 nm. The devices have a flat frequency response over a 1-kHz bandwidth and a resonance frequency of about 3 kHz. The response is linear...... up to at least 15 g and sensitivities as high as 19 pm/g (shift in resonance wavelength per unit acceleration) have been demonstrated. Given that 15 g corresponds to a strain of less than 0.02% and that polymer fibers have an elastic limit of more than 1%, the polymer FBG accelerometer can measure...... very strong accelerations. We compare with corresponding silica FBG accelerometers and demonstrate that using polymer FBGs improves the sensitivity by more than a factor of four and increases the figure of merit, defined as the sensitivity times the resonance frequency squared....

  7. Data and Analytics to Inform Energy Retrofit of High Performance Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Tianzhen; Yang, Le; Hill, David; Feng, Wei

    2014-01-25

    Buildings consume more than one-third of the world?s primary energy. Reducing energy use in buildings with energy efficient technologies is feasible and also driven by energy policies such as energy benchmarking, disclosure, rating, and labeling in both the developed and developing countries. Current energy retrofits focus on the existing building stocks, especially older buildings, but the growing number of new high performance buildings built around the world raises a question that how these buildings perform and whether there are retrofit opportunities to further reduce their energy use. This is a new and unique problem for the building industry. Traditional energy audit or analysis methods are inadequate to look deep into the energy use of the high performance buildings. This study aims to tackle this problem with a new holistic approach powered by building performance data and analytics. First, three types of measured data are introduced, including the time series energy use, building systems operating conditions, and indoor and outdoor environmental parameters. An energy data model based on the ISO Standard 12655 is used to represent the energy use in buildings in a three-level hierarchy. Secondly, a suite of analytics were proposed to analyze energy use and to identify retrofit measures for high performance buildings. The data-driven analytics are based on monitored data at short time intervals, and cover three levels of analysis ? energy profiling, benchmarking and diagnostics. Thirdly, the analytics were applied to a high performance building in California to analyze its energy use and identify retrofit opportunities, including: (1) analyzing patterns of major energy end-use categories at various time scales, (2) benchmarking the whole building total energy use as well as major end-uses against its peers, (3) benchmarking the power usage effectiveness for the data center, which is the largest electricity consumer in this building, and (4) diagnosing HVAC

  8. Elastic-plastic study on high building with SRC transferring story

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A new type of transferring structure for steel reinforced concrete (SRC) beams is used in high building. The pushover analysis method was used to study the failure mechanism and ductility of SRC transferring structure through consulting pseudo-static test results for the structure. And, the occurrence order and position of the plastic hinge, the weak story and seismic capacity of high building with SRC transferring story were also studied through consulting shaking table test results for the high building, showing that the seismic behavior of high building with SRC transferring story is good.

  9. Are Inflationary Predictions Sensitive to Very High Energy Physics?

    CERN Document Server

    Burgess, C P; Lemieux, F; Holman, R

    2003-01-01

    It has been proposed that the successful inflationary description of density perturbations on cosmological scales is sensitive to the details of physics at extremely high (trans-Planckian) energies. We test this proposal by examining how inflationary predictions depend on higher-energy scales within a simple model where the higher-energy physics is well understood. We find the best of all possible worlds: inflationary predictions are robust against the vast majority of high-energy effects, but can be sensitive to some effects in certain circumstances, in a way which does not violate ordinary notions of decoupling. This implies both that the comparison of inflationary predictions with CMB data is meaningful, and that it is also worth searching for small deviations from the standard results in the hopes of learning about very high energies.

  10. Design of highly sensitive multichannel bimetallic photonic crystal fiber biosensor

    Science.gov (United States)

    Hameed, Mohamed Farhat O.; Alrayk, Yassmin K. A.; Shaalan, Abdelhamid A.; El Deeb, Walid S.; Obayya, Salah S. A.

    2016-10-01

    A design of a highly sensitive multichannel biosensor based on photonic crystal fiber is proposed and analyzed. The suggested design has a silver layer as a plasmonic material coated by a gold layer to protect silver oxidation. The reported sensor is based on detection using the quasi transverse electric (TE) and quasi transverse magnetic (TM) modes, which offers the possibility of multichannel/multianalyte sensing. The numerical results are obtained using a finite element method with perfect matched layer boundary conditions. The sensor geometrical parameters are optimized to achieve high sensitivity for the two polarized modes. High-refractive index sensitivity of about 4750 nm/RIU (refractive index unit) and 4300 nm/RIU with corresponding resolutions of 2.1×10-5 RIU, and 2.33×10-5 RIU can be obtained according to the quasi TM and quasi TE modes of the proposed sensor, respectively. Further, the reported design can be used as a self-calibration biosensor within an unknown analyte refractive index ranging from 1.33 to 1.35 with high linearity and high accuracy. Moreover, the suggested biosensor has advantages in terms of compactness and better integration of microfluidics setup, waveguide, and metallic layers into a single structure.

  11. Sensitivity of HAWC to high-mass dark matter annihilations

    Science.gov (United States)

    Abeysekara, A. U.; Alfaro, R.; Alvarez, C.; Álvarez, J. D.; Arceo, R.; Arteaga-Velázquez, J. C.; Ayala Solares, H. A.; Barber, A. S.; Baughman, B. M.; Bautista-Elivar, N.; Becerra Gonzalez, J.; Belmont, E.; BenZvi, S. Y.; Berley, D.; Bonilla Rosales, M.; Braun, J.; Caballero-Lopez, R. A.; Caballero-Mora, K. S.; Carramiñana, A.; Castillo, M.; Cotti, U.; Cotzomi, J.; de la Fuente, E.; De León, C.; DeYoung, T.; Diaz Hernandez, R.; Diaz-Cruz, L.; Díaz-Vélez, J. C.; Dingus, B. L.; DuVernois, M. A.; Ellsworth, R. W.; Fiorino, D. W.; Fraija, N.; Galindo, A.; Garfias, F.; González, M. M.; Goodman, J. A.; Grabski, V.; Gussert, M.; Hampel-Arias, Z.; Harding, J. P.; Hui, C. M.; Hüntemeyer, P.; Imran, A.; Iriarte, A.; Karn, P.; Kieda, D.; Kunde, G. J.; Lara, A.; Lauer, R. J.; Lee, W. H.; Lennarz, D.; León Vargas, H.; Linares, E. C.; Linnemann, J. T.; Longo, M.; Luna-Garcia, R.; Marinelli, A.; Martinez, H.; Martinez, O.; Martínez-Castro, J.; Matthews, J. A. J.; McEnery, J.; Mendoza Torres, E.; Miranda-Romagnoli, P.; Moreno, E.; Mostafá, M.; Nellen, L.; Newbold, M.; Noriega-Papaqui, R.; Oceguera-Becerra, T.; Patricelli, B.; Pelayo, R.; Pérez-Pérez, E. G.; Pretz, J.; Rivière, C.; Rosa-González, D.; Ryan, J.; Salazar, H.; Salesa, F.; Sanchez, F. E.; Sandoval, A.; Schneider, M.; Silich, S.; Sinnis, G.; Smith, A. J.; Sparks Woodle, K.; Springer, R. W.; Taboada, I.; Toale, P. A.; Tollefson, K.; Torres, I.; Ukwatta, T. N.; Villaseñor, L.; Weisgarber, T.; Westerhoff, S.; Wisher, I. G.; Wood, J.; Yodh, G. B.; Younk, P. W.; Zaborov, D.; Zepeda, A.; Zhou, H.; Abazajian, K. N.; Milagro Collaboration

    2014-12-01

    The High Altitude Water Cherenkov (HAWC) observatory is a wide field-of-view detector sensitive to gamma rays of 100 GeV to a few hundred TeV. Located in central Mexico at 19° North latitude and 4100 m above sea level, HAWC will observe gamma rays and cosmic rays with an array of water Cherenkov detectors. The full HAWC array is scheduled to be operational in Spring 2015. In this paper, we study the HAWC sensitivity to the gamma-ray signatures of high-mass (multi-TeV) dark matter annihilation. The HAWC observatory will be sensitive to diverse searches for dark matter annihilation, including annihilation from extended dark matter sources, the diffuse gamma-ray emission from dark matter annihilation, and gamma-ray emission from nonluminous dark matter subhalos. Here we consider the HAWC sensitivity to a subset of these sources, including dwarf galaxies, the M31 galaxy, the Virgo cluster, and the Galactic center. We simulate the HAWC response to gamma rays from these sources in several well-motivated dark matter annihilation channels. If no gamma-ray excess is observed, we show the limits HAWC can place on the dark matter cross section from these sources. In particular, in the case of dark matter annihilation into gauge bosons, HAWC will be able to detect a narrow range of dark matter masses to cross sections below thermal. HAWC should also be sensitive to nonthermal cross sections for masses up to nearly 1000 TeV. The constraints placed by HAWC on the dark matter cross section from known sources should be competitive with current limits in the mass range where HAWC has similar sensitivity. HAWC can additionally explore higher dark matter masses than are currently constrained.

  12. Indoor air quality in green buildings: A case-study in a residential high-rise building in the northeastern United States.

    Science.gov (United States)

    Xiong, Youyou; Krogmann, Uta; Mainelis, Gediminas; Rodenburg, Lisa A; Andrews, Clinton J

    2015-01-01

    Improved indoor air quality (IAQ) is one of the critical components of green building design. Green building tax credit (e.g., New York State Green Building Tax Credit (GBTC)) and certification programs (e.g., Leadership in Energy & Environmental Design (LEED)) require indoor air quality measures and compliance with allowable maximum concentrations of common indoor air pollutants. It is not yet entirely clear whether compliance with these programs results in improved IAQ and ultimately human health. As a case in point, annual indoor air quality measurements were conducted in a residential green high-rise building for five consecutive years by an industrial hygiene contractor to comply with the building's GBTC requirements. The implementation of green design measures resulted in better IAQ compared to data in references of conventional homes for some parameters, but could not be confirmed for others. Relative humidity and carbon dioxide were satisfactory according to existing standards. Formaldehyde levels during four out of five years were below the most recent proposed exposure limits found in the literature. To some degree, particulate matter (PM) levels were lower than that in studies from conventional residential buildings. Concentrations of Volatile Organic Compounds (VOCs) with known permissible exposure limits were below levels known to cause chronic health effects, but their concentrations were inconclusive regarding cancer health effects due to relatively high detection limits. Although measured indoor air parameters met all IAQ maximum allowable concentrations in GBTC and applicable LEED requirements at the time of sampling, we argue that these measurements were not sufficient to assess IAQ comprehensively because more sensitive sampling/analytical methods for PM and VOCs are needed; in addition, there is a need for a formal process to ensure rigor and adequacy of sampling and analysis methods. Also, we suggest that a comprehensive IAQ assessment should

  13. Development of High Sensitivity Nuclear Emulsion and Fine Grained Emulsion

    Energy Technology Data Exchange (ETDEWEB)

    Kawahara, H.; Asada, T. [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Naka, T. [Institute of Advanced Research, Nagoya University (Japan); Naganawa, N.; Kuwabara, K.; Nakamura, M. [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan)

    2014-08-15

    Nuclear emulsion is a particle detector having high spacial resolution and angular resolution. It became useful for large statistics experiment thanks to the development of automatic scanning system. In 2010, a facility for emulsion production was introduced and R and D of nuclear emulsion began at Nagoya university. In this paper, we present results of development of the high sensitivity emulsion and fine grained emulsion for dark matter search experiment. Improvement of sensitivity is achieved by raising density of silver halide crystals and doping well-adjusted amount of chemicals. Production of fine grained emulsion was difficult because of unexpected crystal condensation. By mixing polyvinyl alcohol (PVA) to gelatin as a binder, we succeeded in making a stable fine grained emulsion.

  14. Highly sensitive troponin T in patients with acute ischemic stroke

    DEFF Research Database (Denmark)

    Jensen, J K; Ueland, T; Aukrust, P;

    2012-01-01

    in decedents than in survivors. After adjustment for stroke severity, C-reactive protein, age, NT-proBNP and prior heart and/or renal failure, hsTnT levels were not a significant predictor of long-term all-cause or cardiovascular mortality. Conclusion: Elevated levels of hsTnT are frequently present......Background: Newly developed troponin assays have superior diagnostic and prognostic performance in acute coronary syndrome (ACS), when compared to conventional troponin assays; however, highly sensitive troponin has not been evaluated in patients with acute ischemic stroke. Methods: Highly...... sensitive troponin T (hsTnT) was measured daily during the first 4 days in 193 consecutive patients with acute ischemic stroke without overt ACS or atrial fibrillation. The patients were previously tested normal with a fourth-generation TnT assay. The patients were followed for 47 months, with all...

  15. Structural Glycomic Analyses at High Sensitivity: A Decade of Progress

    Science.gov (United States)

    Alley, William R.; Novotny, Milos V.

    2013-06-01

    The field of glycomics has recently advanced in response to the urgent need for structural characterization and quantification of complex carbohydrates in biologically and medically important applications. The recent success of analytical glycobiology at high sensitivity reflects numerous advances in biomolecular mass spectrometry and its instrumentation, capillary and microchip separation techniques, and microchemical manipulations of carbohydrate reactivity. The multimethodological approach appears to be necessary to gain an in-depth understanding of very complex glycomes in different biological systems.

  16. Highly Sensitive Flexible Magnetic Sensor Based on Anisotropic Magnetoresistance Effect.

    Science.gov (United States)

    Wang, Zhiguang; Wang, Xinjun; Li, Menghui; Gao, Yuan; Hu, Zhongqiang; Nan, Tianxiang; Liang, Xianfeng; Chen, Huaihao; Yang, Jia; Cash, Syd; Sun, Nian-Xiang

    2016-11-01

    A highly sensitive flexible magnetic sensor based on the anisotropic magnetoresistance effect is fabricated. A limit of detection of 150 nT is observed and excellent deformation stability is achieved after wrapping of the flexible sensor, with bending radii down to 5 mm. The flexible AMR sensor is used to read a magnetic pattern with a thickness of 10 μm that is formed by ferrite magnetic inks.

  17. Federal High Performance and Sustainable Buildings: Guiding Principles for the Laboratory Support Building (LSB)

    Energy Technology Data Exchange (ETDEWEB)

    Pope, Jason E.

    2014-09-01

    This report documents the federal Guiding Principles conformance effort for LSB at PNNL. The effort is part of continued progress toward a campus building inventory that is 100% compliant with the Guiding Principles. The report documentation provides a narrative of how the LSB complies with each of the Guiding Principles requirements. These narratives draw from the many sources that are explained in the text and rely on extensive data collection. The descriptions point to each of these sources, providing the reader with specific policies, procedures, and data points.

  18. A Study on Problems Arises in Practicing Fire Drill in High Rise Building in Kuala Lumpur

    Directory of Open Access Journals (Sweden)

    Zahari N.F.

    2014-01-01

    Full Text Available Fire drill is one of the steps taken to mitigate the risk trapped in a building during outbreak of fire. Hence, it is very important for every building to practice fire drill, especially high-rise building. Referring to Fire and Rescue Department of Malaysia(BOMBA, high-rise building had a higher risk compared to other type of buildings. However, there might be problems arise to practice fire drill especially in high-rise building. This research intends to study on fire drill procedure and identify any possible common problems arises when practicing fire drill in high-rise building in Kuala Lumpur. Information was gained through regulations and guidelines associated with fire drill procedure and also parties involved in the practice. Besides, a survey is done for awareness of occupants in high-rise building on fire drill practice. For the case study, three high-rise building are selected in Kuala Lumpur based on specific criteria. Analysis for this research comprises of comparative and descriptive approach as well as statistical analysis which are documented based on case studies and questionnaire survey. The findings indicates that there is no standardized procedure in fire drill, while the most common problems that can be seen in practicing fire drill are lack of commitment among occupants, lack of information on fire drill and output on weaknesses after fire drill been practiced.

  19. Building America System Research Results. Innovations for High Performance Homes

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2006-05-01

    This report provides a summary of key lessons learned from the first 10 years of the Building America program and also included a summary of the future challenges that must be met to reach the program’s long term performance goals.

  20. Recent trends in high spin sensitivity magnetic resonance

    Science.gov (United States)

    Blank, Aharon; Twig, Ygal; Ishay, Yakir

    2017-07-01

    new ideas, show how these limiting factors can be mitigated to significantly improve the sensitivity of induction detection. Finally, we outline some directions for the possible applications of high-sensitivity induction detection in the field of electron spin resonance.

  1. Investigation of fire-induced collapse scenarios for a steel high-rise building

    DEFF Research Database (Denmark)

    Gentili, Filippo; Giuliani, Luisa; Bontempi, Franco

    2011-01-01

    (architectural design choices and active measures) and won’t be investigated in detail in this paper; the paper focus instead on structural design aspects, with specific reference to the iii) enhanced susceptibility of high-rise buildings to disproportionate collapse, due to the significant vertical elevation......The paper deals with the problem of understanding and evaluating the structural response of steel buildings to fire and outlines a general framework for the structural fire safety design of high-rise building. Among all building typology, the fire design of high-rise buildings is particularly...... challenging with respect to both non-structural and structural design aspects: the enhanced design difficulties in providing i) a safe and prompt vertical evacuation of the building and ii) an effective vertical compartmentalization for avoiding vertical fire spread, refer both to non-structural aspects...

  2. Pulsed Discharge Helium Ionization Detector for Highly Sensitive Aquametry.

    Science.gov (United States)

    Mowry, Curtis D; Pimentel, Adam S; Sparks, Elizabeth S; Moorman, Matthew W; Achyuthan, Komandoor E; Manginell, Ronald P

    2016-01-01

    Trace moisture quantitation is crucial in medical, civilian and military applications. Current aquametry technologies are limited by the sample volume, reactivity, or interferences, and/or instrument size, weight, power, cost, and complexity. We report for the first time on the use of a pulsed discharge helium ionization detector (PDHID-D2) (∼196 cm(3)) for the sensitive (limit of detection, 0.047 ng; 26 ppm), linear (r(2) >0.99), and rapid (volume of liquid or gas. The relative humidity sensitivity was 0.22% (61.4 ppmv) with a limit of detection of less than 1 ng moisture with gaseous samples. The sensitivity was 10 to 100 to fold superior to competing technologies without the disadvantages inherent to these technologies. The PDHID-D2, due to its small footprint and low power requirement, has good size, weight, and power-portability (SWAPP) factors. The relatively low cost (∼$5000) and commercial availability of the PDHID-D2 makes our technique applicable to highly sensitive aquametry.

  3. Development of a highly sensitive galvanic cell oxygen sensor.

    Science.gov (United States)

    Ogino, H; Asakura, K

    1995-02-01

    A highly sensitive galvanic cell oxygen sensor was successfully developed for determining parts per billion of oxygen in high purity gases such as nitrogen, argon, etc. The response of this improved sensor was proportional in the range of oxygen concentrations from 10.0 ppm to the detection limit. The response speed in this study was improved to within 90 sec for a 90% response. The detection limit was tentatively found to be less than 0.4 ppb corresponding to S N = 2 .

  4. Method for integrated design of low energy buildings with high quality indoor environment

    DEFF Research Database (Denmark)

    Petersen, Steffen

    2008-01-01

    Energy performance and indoor environment have due to new increased regulatory demands become decisive design parameters in the building design process. In order to comply with the increased regulatory demands, we present an integrated design method which argues that the design of buildings must ...... to become the preferred method for integrated design of low energy buildings with high quality indoor environment.......Energy performance and indoor environment have due to new increased regulatory demands become decisive design parameters in the building design process. In order to comply with the increased regulatory demands, we present an integrated design method which argues that the design of buildings must...... start on room level rather than total building level. The proposed method starts with the establishment of design goals, including goals regarding energy performance and indoor environment, followed by a building physical analysis of performance-decisive parameters. This analysis is used to establish...

  5. A novel high-throughput irradiator for in vitro radiation sensitivity bioassays

    Science.gov (United States)

    Fowler, Tyler L.

    Given the emphasis on more personalized radiation therapy there is an ongoing and compelling need to develop high-throughput screening tools to further examine the biological effects of ionizing radiation on cells, tissues and organ systems in either the research or clinical setting. Conventional x-ray irradiators are designed to provide maximum versatility to radiobiology researchers, typically accommodating small animals, tissue or blood samples, and cellular applications. This added versatility often impedes the overall sensitivity and specificity of an experiment resulting in a trade-off between the number of absorbed doses (or dose rates) and biological endpoints that can be investigated in vitro in a reasonable amount of time. Therefore, modern irradiator designs are incompatible with current high-throughput bioassay technologies. Furthermore, important dosimetry and calibration characteristics (i.e. dose build-up region, beam attenuation, and beam scatter) of these irradiators are typically unknown to the end user, which can lead to significant deviation between delivered dose and intended dose to cells that adversely impact experimental results. Therefore, the overarching goal of this research is to design and develop a robust and fully automated high-throughput irradiator for in vitro radiation sensitivity investigations. Additionally, in vitro biological validation of this system was performed by assessing intracellular reactive oxygen species production, physical DNA double strand breaks, and activation of cellular DNA repair mechanisms. Finally, the high-throughput irradiator was used to investigate autophagic flux, a cellular adaptive response, as a potential biomarker of radiation sensitivity.

  6. Performance of terahertz metamaterials as high-sensitivity sensor

    Science.gov (United States)

    He, Yanan; Zhang, Bo; Shen, Jingling

    2017-09-01

    A high-sensitivity sensor based on the resonant transmission characteristics of terahertz (THz) metamaterials was investigated, with the proposal and fabrication of rectangular bar arrays of THz metamaterials exhibiting a period of 180 μm on a 25 μm thick flexible polyimide. Varying the size of the metamaterial structure revealed that the length of the rectangular unit modulated the resonant frequency, which was verified by both experiment and simulation. The sensing characteristics upon varying the surrounding media in the sample were tested by simulation and experiment. Changing the surrounding medium from that of air to that of alcohol or oil produced resonant frequency redshifts of 80 GHz or 150 GHz, respectively, which indicates that the sensor possessed a high sensitivity of 667 GHz per unit of refractive index. Finally, the influence of the sample substrate thickness on the sensor sensitivity was investigated by simulation. It may be a reference for future sensor design.

  7. High-sensitivity strain visualization using electroluminescence technologies

    Science.gov (United States)

    Xu, Jian; Jo, Hongki

    2016-04-01

    Visualizing mechanical strain/stress changes is an emerging area in structural health monitoring. Several ways are available for strain change visualization through the color/brightness change of the materials subjected to the mechanical stresses, for example, using mechanoluminescence (ML) materials and mechanoresponsive polymers (MRP). However, these approaches were not effectively applicable for civil engineering system yet, due to insufficient sensitivity to low-level strain of typical civil structures and limitation in measuring both static and dynamic strain. In this study, design and validation for high-sensitivity strain visualization using electroluminescence technologies are presented. A high-sensitivity Wheatstone bridge, of which bridge balance is precisely controllable circuits, is used with a gain-adjustable amplifier. The monochrome electroluminescence (EL) technology is employed to convert both static and dynamic strain change into brightness/color change of the EL materials, through either brightness change mode (BCM) or color alternation mode (CAM). A prototype has been made and calibrated in lab, the linearity between strain and brightness change has been investigated.

  8. High-sensitive scanning laser magneto-optical imaging system.

    Science.gov (United States)

    Murakami, Hironaru; Tonouchi, Masayoshi

    2010-01-01

    A high-sensitive scanning laser magneto-optical (MO) imaging system has been developed. The system is mainly composed of a laser source, galvano meters, and a high-sensitive differential optical-detector. Preliminary evaluation of system performance by using a Faraday indicator with a Faraday rotation coefficient of 3.47 x 10(-5) rad/microm Oe shows a magnetic sensitivity of about 5 microT, without any need for accumulation or averaging processing. Using the developed MO system we have succeeded in the fast and quantitative imaging of a rotationally symmetric magnetic field distribution around an YBa(2)Cu(3)O(7-delta) (YBCO) strip line applied with dc-biased current, and also succeeded in the detection of quantized fine signals corresponding to magnetic flux quantum generation in a superconducting loop of an YBCO Josephson vortex flow transistor. Thus, the developed system enables us not only to do fast imaging and local signal detection but also to directly evaluate both the strength and direction of a magnetic signal.

  9. HIGHLY SENSITIVE CATALASE ELECTRODE BASED ON POLYPYRROLE FILMS WITH MICROCONTAINERS

    Institute of Scientific and Technical Information of China (English)

    Yu-ying Gao; Gao-quan Shi

    2006-01-01

    Highly sensitive catalase electrodes for sensing hydrogen peroxide have been fabricated based on polypyrrole films with microcontainers. The microcontainers have a cup-like morphology and are arranged in a density of 4000 units cm-2.Catalase was immobilized into the polypyrrole films with microcontainers (Ppy-mc), which were coated on a Pt substrate electrode. The catalase/Ppy-mc/Pt electrode showed linear response to hydrogen peroxide in the range of 0-18 mmol/L at a potential of -0.3 V (versus SCE). Its sensitivity was measured to be approximately 3.64 μA (mmol/L)-1 cm-2, which is about two times that of the electrode fabricated from a flat Ppy film (catalase/Ppy-flat/Pt electrode). The electrode is highly selective for hydrogen peroxide and its sensitivity is interfered by potential interferents such as ascorbic acid, urea and fructose. Furthermore, such catalase electrodes showed long-term storage stability of 15 days under dry conditions at 4℃.

  10. SEISMIC Analysis of high-rise buildings with composite metal damper

    Directory of Open Access Journals (Sweden)

    Chen Ruixue

    2015-01-01

    Full Text Available This paper mainly studies on the mechanical characteristics and application effect of composite metal damper in the high-rise buildings via the numerical simulation analysis. The research adopts the elastic and elastic-plastic dynamic approach and the displacement time history response and damper energy dissipation capacity and so on of the high-rise building are compared and analyzed before and after installation. The analysis found that the energy dissipation characteristic of metallic dampers is good. High-rise building story drift significantly is reduced and the extent of damage of the walls and coupling beams is decreased, achieved a good energy dissipation effect. Composite metal damper can effectively and economically improve the seismic performance of high-rise buildings, meet the requirement of the 3-level design for seismic resistance. The result has certain reference significance for the application of metallic damper in the high-rise buildings.

  11. Development of highly sensitive monolithic interferometer for infrared planet search

    Directory of Open Access Journals (Sweden)

    Jiang P.

    2011-07-01

    Full Text Available We present the design, fabrication and testing of a highly sensitive monolithic interferometer for InfraRed Exoplanet Tracker (IR-ET. This interferometer is field-compensated, thermal-stable for working in the wavelength range between 0.8 and 1.35 μm. Two arms of the interferometer creates a fixed delay of 18.0 mm, which is optimized to have the best sensitivity for radial velocity measurements of slow-rotating M dwarfs for planet detection. IR-ET is aiming to reach 3–20 m/s Doppler precision for J<10 M dwarfs in less than 15 min exposures. We plan to conduct a planet survey around hundreds of nearby M dwarfs through collaborations with Astrophysical Research Consortium scientists in 2011–2014.

  12. Polymer-Particle Pressure-Sensitive Paint with High Photostability

    Directory of Open Access Journals (Sweden)

    Yu Matsuda

    2016-04-01

    Full Text Available We propose a novel fast-responding and paintable pressure-sensitive paint (PSP based on polymer particles, i.e. polymer-particle (pp-PSP. As a fast-responding PSP, polymer-ceramic (PC-PSP is widely studied. Since PC-PSP generally consists of titanium (IV oxide (TiO2 particles, a large reduction in the luminescent intensity will occur due to the photocatalytic action of TiO2. We propose the usage of polymer particles instead of TiO2 particles to prevent the reduction in the luminescent intensity. Here, we fabricate pp-PSP based on the polystyrene particle with a diameter of 1 μm, and investigate the pressure- and temperature-sensitives, the response time, and the photostability. The performances of pp-PSP are compared with those of PC-PSP, indicating the high photostability with the other characteristics comparable to PC-PSP.

  13. New application of superconductors: high sensitivity cryogenic light detectors

    CERN Document Server

    Cardani, L; Casali, N; Casellano, M G; Colantoni, I; Coppolecchia, A; Cosmelli, C; Cruciani, A; D'Addabbo, A; Di Domizio, S; Martinez, M; Tomei, C; Vignati, M

    2016-01-01

    In this paper we describe the current status of the CALDER project, which is developing ultra-sensitive light detectors based on superconductors for cryogenic applications. When we apply an AC current to a superconductor, the Cooper pairs oscillate and acquire kinetic inductance, that can be measured by inserting the superconductor in a LC circuit with high merit factor. Interactions in the superconductor can break the Cooper pairs, causing sizable variations in the kinetic inductance and, thus, in the response of the LC circuit. The continuous monitoring of the amplitude and frequency modulation allows to reconstruct the incident energy with excellent sensitivity. This concept is at the basis of Kinetic Inductance Detectors (KIDs), that are characterized by natural aptitude to multiplexed read-out (several sensors can be tuned to different resonant frequencies and coupled to the same line), resolution of few eV, stable behavior over a wide temperature range, and ease in fabrication. We present the results ob...

  14. OPTIMAL DESIGN OF HIGH-RISE BUILDING BUNDLED TUBE SYSTEMS

    Directory of Open Access Journals (Sweden)

    Hojat Allah Ghasemi

    2016-06-01

    Full Text Available The primary objectives of this study are to investigate effects of varying design parameters on the tube action and shear lag behavior of a typical reinforced concrete bundled tube building, and propose optimal design approaches for similar structures. A parametric study was conducted with selected key design variables on the performance of a 41 story building. The design variables considered for the parametric study include the column depth, beam depth, column width and beam width of the moment frames. The performance of each model was assessed in terms of overall and critical (maximum story drifts, and shear lag behavior. Overall, the effects of the column depth on the tube action and shear lag behavior were more prominent than the other member dimensions.

  15. LDDX: A High Efficiency Air Conditioner for DOD Buildings

    Science.gov (United States)

    2017-02-01

    cooling market . 7.1.2 Solving Building Humidity Problems Despite the preceding simplified analysis showing that a very large segment of the HVAC market ...this demonstration is to show that comfortable indoor conditions can be maintained in a large segment of DOD’s installations with a significant...unlikely that any cooling technology that provides an enhanced latent capacity will successfully compete in this broad segment of the comfort

  16. Design, Monitoring, and Validation of a High Performance Sustainable Building

    Science.gov (United States)

    2013-08-01

    system Rainwater collected by roof and drains to the 10,000 gallon cistern below grade Not applicable Sewage conveyance Rainwater Potable water...rating system was used as the baseline for the whole building design objectives. Monitoring data for energy and water use were collected at the...performance metrics that address the research needs and sustainable design goals of the project b. establish data collection system that allows for data

  17. Highly sensitive detection of urinary cadmium to assess personal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Argun, Avni A.; Banks, Ashley M.; Merlen, Gwendolynne; Tempelman, Linda A. [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States); Becker, Michael F.; Schuelke, Thomas [Fraunhofer USA – CCL, 1449 Engineering Research Ct., East Lansing 48824, MI (United States); Dweik, Badawi M., E-mail: bdweik@ginerinc.com [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States)

    2013-04-22

    Highlights: ► An electrochemical sensor capable of detecting cadmium at parts-per-billion levels in urine. ► A novel fabrication method for Boron-Doped Diamond (BDD) ultramicroelectrode (UME) arrays. ► Unique combination of BDD UME arrays and a differential pulse voltammetry algorithm. ► High sensitivity, high reproducibility, and very low noise levels. ► Opportunity for portable operation to assess on-site personal exposure. -- Abstract: A series of Boron-Doped Diamond (BDD) ultramicroelectrode arrays were fabricated and investigated for their performance as electrochemical sensors to detect trace level metals such as cadmium. The steady-state diffusion behavior of these sensors was validated using cyclic voltammetry followed by electrochemical detection of cadmium in water and in human urine to demonstrate high sensitivity (>200 μA ppb{sup −1} cm{sup −2}) and low background current (<4 nA). When an array of ultramicroelectrodes was positioned with optimal spacing, these BDD sensors showed a sigmoidal diffusion behavior. They also demonstrated high accuracy with linear dose dependence for quantification of cadmium in a certified reference river water sample from the U.S. National Institute of Standards and Technology (NIST) as well as in a human urine sample spiked with 0.25–1 ppb cadmium.

  18. [Highly sensitive detection technology for biological toxins applying sugar epitopes].

    Science.gov (United States)

    Uzawa, Hirotaka

    2009-01-01

    The Shiga toxin is a highly poisonous protein produced by enterohemorrhagic Escherichia coli O157. This bacterial toxin causes the hemolytic uremic syndrome. Another plant toxin from castor beans, ricin, is also highly toxic. The toxin was used for assassination in London. Recently, there were several cases of postal matter containing ricin. Both toxins are categorized as biological warfare agents by the Centers of Disease Control and Prevention. Conventional detection methods based on the antigen-antibody reaction, PCR and other cell-free assays have been proposed. However, those approaches have drawbacks in terms of sensitivity, analytical time, or stability of the detection reagents. Therefore, development of a facile and sensitive detection method is essential. Here we describe new detection methods applying carbohydrate epitopes as the toxin ligands, which is based on the fact that the toxins bind cell-surface oligosaccharides. Namely, the Shiga toxin has an affinity for globobiosyl (Gb(2)) disaccharide, and ricin binds the beta-D-galactose residue. For Shiga toxin detection, surface plasmon resonance (SPR) was applied. A polyanionic Gb(2)-glycopolymer was designed for this purpose, and it was used for the assembly of Gb(2)-chips using alternating layer-by-layer technology. The method allowed us to detect the toxin at a low concentration of LD(50). A synthetic carbohydrate ligand for ricin was designed and immobilized on the chips. SPR analysis with the chips allows us to detect ricin in a highly sensitive and facile manner (10 pg/ml, 5 min). Our present approaches provide a highly effective way to counter bioterrorism.

  19. Effects of Bracing of High-Rise Buildings upon their Static and Dynamic Behavior

    Directory of Open Access Journals (Sweden)

    Ivánková Oľga

    2014-05-01

    Full Text Available The paper describes effects of bracing of high-rise buildings upon their static and dynamic behaviour. In static and dynamic analyses, values of displacement for 4 different variants of stiffening elements distribution were calculated. The calculations were made for building both fixed into the ground and rested on elastic supports. The building was modelled as a 3D variant using Finite Element Method (FEM in program Scia Engineer.

  20. Influence of Smoking on Ultra-High-Frequency Auditory Sensitivity.

    Science.gov (United States)

    Prabhu, Prashanth; Varma, Gowtham; Dutta, Kristi Kaveri; Kumar, Prajwal; Goyal, Swati

    2017-04-01

    In this study, an attempt was made to determine the effect of smoking on ultra-high-frequency auditory sensitivity. The study also attempted to determine the relationship between the nature of smoking and ultra-high-frequency otoacoustic emissions (OAEs) and thresholds. The study sample included 25 smokers and 25 non-smokers. A detailed history regarding their smoking habits was collected. High-frequency audiometric thresholds and amplitudes of high-frequency distortion-product OAEs were analyzed for both ears from all participants. The results showed that the ultra-high-frequency thresholds were elevated and that there was reduction in the amplitudes of ultra-high-frequency OAEs in smokers. There was an increased risk of auditory damage with chronic smoking. The study results highlight the application of ultra-high-frequency OAEs and ultra-high-frequency audiometry for the early detection of auditory impairment. However, similar studies should be conducted on a larger population for better generalization of the results.

  1. Towards energy efficient high-rise residential building enclosures: insight from energy bills and enclosure rehabilitations

    Energy Technology Data Exchange (ETDEWEB)

    Finch, Graham; Knowles, Warren; Ricketts, Lorne [RDH Building Engineering Ltd., Vancouver, (Canada)

    2010-07-01

    The building industry is looking to reduce energy consumption and the environmental impact of all building types. This paper investigated the relationship between current building practices and space heating in high-rise multi-unit residential buildings (MURBs). A summary of some of the key findings from a larger study with a focus on issues related to building enclosure conductive thermal losses was presented. This work involved the assessment of energy consumption data and, more specifically, of the space heating characteristics for mid and high-rise MURBs in the Lower Mainland of Vancouver which were selected as representative of typical MURB housing stock and included buildings with architectural forms common to other mid and high-rise residential buildings across North America. The effective R-value for all building enclosure assemblies for each building was calculated and compared with energy bills. The R-values were compared to ASHRAE 90.1. It was found that the overall effective R-values ranges were between R-2 and R-5 ft2 hr F/Btu.

  2. Ultrathin plasmonic nanogratings for rapid and highly-sensitive detection

    CERN Document Server

    Zeng, Beibei; Bartoli, Filbert J

    2014-01-01

    We developed a nanoplasmonic sensor platform employing the extraordinary optical properties of one-dimensional nanogratings patterned on 30nm-thick ultrathin Ag films. Excitation of Fano resonances in the ultrathin Ag nanogratings results in transmission spectra with high amplitude, large contrast, and narrow bandwidth, making them well-suited for rapid and highly-sensitive sensing applications. The ultrathin nanoplasmonic sensor chip was integrated with a polydimethylsiloxane (PDMS) microfluidic channel, and the measured refractive index resolution was found to be 1.46x10-6 refractive index units (RIU) with a high temporal resolution of 1 sec. This compares favorably with commercial prism-based surface plasmon resonance sensors, but is achieved using a more convenient collinear transmission geometry and a significantly smaller sensor footprint of 50x50um2. In addition, an order-of-magnitude improvement in the temporal and spatial resolutions was achieved relative to state-of-the-art nanoplasmonic sensors, fo...

  3. Potential programs for high sensitivity FIR spectroscopy with SPICA

    CERN Document Server

    Spinoglio, L; Saraceno, P; Spinoglio, Luigi; Giorgio, Anna Maria Di; Saraceno, Paolo

    2006-01-01

    We discuss the potential of high sensitivity mid-IR and far-IR spectroscopy to proof the physical properties of active nuclei and starburst regions of local and distant galaxies. For local galaxies, it will be possible to map the discs and ISM through the low ionization ionic lines and a variety of molecular tracers, such as OH, H2O and high-J CO. At increasing distance, most of the ionic nebular lines (typical of stars and AGNs) are shifted into the FIR, making possible to compare the observed spectra with those predicted by different evolutionary scenarios. At the very high redshift of 10-15, sensitive mid-to-far-IR spectrometers, such as those planned to be at the focal plane of the future SPICA mision, could be adequate to detect the H recombination lines excited in the HII regions around population III stars, if these stars happened to reside in large clusters of more than 10^5 members.

  4. High-sensitivity piezoelectric perovskites for magnetoelectric composites

    Science.gov (United States)

    Amorín, Harvey; Algueró, Miguel; Campo, Rubén Del; Vila, Eladio; Ramos, Pablo; Dollé, Mickael; Romaguera-Barcelay, Yonny; Cruz, Javier Pérez De La; Castro, Alicia

    2015-01-01

    A highly topical set of perovskite oxides are high-sensitivity piezoelectric ones, among which Pb(Zr,Ti)O3 at the morphotropic phase boundary (MPB) between ferroelectric rhombohedral and tetragonal polymorphic phases is reckoned a case study. Piezoelectric ceramics are used in a wide range of mature, electromechanical transduction technologies like piezoelectric sensors, actuators and ultrasound generation, to name only a few examples, and more recently for demonstrating novel applications like magnetoelectric composites. In this case, piezoelectric perovskites are combined with magnetostrictive materials to provide magnetoelectricity as a product property of the piezoelectricity and piezomagnetism of the component phases. Interfaces play a key issue, for they control the mechanical coupling between the piezoresponsive phases. We present here main results of our investigation on the suitability of the high sensitivity MPB piezoelectric perovskite BiScO3–PbTiO3 in combination with ferrimagnetic spinel oxides for magnetoelectric composites. Emphasis has been put on the processing at low temperature to control reactions and interdiffusion between the two oxides. The role of the grain size effects is extensively addressed. PMID:27877758

  5. Building Cultural Sensitivity and Interprofessional Collaboration Through a Study Abroad Experience.

    Science.gov (United States)

    Gilliland, Irene; Attridge, Russell T; Attridge, Rebecca L; Maize, David F; McNeill, Jeanette

    2016-01-01

    Study abroad (SA) experiences for health professions students may be used to heighten cultural sensitivity to future patients and incorporate interprofessional education (IPE). Two groups of nursing and pharmacy students participated in an SA elective over a 2-year period, traveling to China and India. Both groups improved significantly in knowledge, awareness, and skills following the travel experiences. Student reflections indicate that the SA experience was transformative, changing their views of travel, other cultures, personal environment, collaboration with other health professionals, and themselves. Use of SA programs is a novel method to encourage IPE, with a focus on enhancing the acquisition of cultural competency skills. Copyright 2016, SLACK Incorporated.

  6. Sensitivity analysis of the thermal performance of radiant and convective terminals for cooling buildings

    DEFF Research Database (Denmark)

    Le Dréau, J.; Heiselberg, P.

    2014-01-01

    on both radiation and convection. In order to characterise the advantages and drawbacks of the different terminals, steady-state simulations of a typical office room have been performed using four types of terminals (active chilled beam, radiant floor, wall and ceiling). A sensitivity analysis has been...... conducted to determine the parameters influencing their thermal performance the most. The air change rate, the outdoor temperature and the air temperature stratification have the largest effect on the cooling need (maintaining a constant operative temperature). For air change rates higher than 0.5 ACH...

  7. High-Sensitivity Measurement of Density by Magnetic Levitation.

    Science.gov (United States)

    Nemiroski, Alex; Kumar, A A; Soh, Siowling; Harburg, Daniel V; Yu, Hai-Dong; Whitesides, George M

    2016-03-01

    This paper presents methods that use Magnetic Levitation (MagLev) to measure very small differences in density of solid diamagnetic objects suspended in a paramagnetic medium. Previous work in this field has shown that, while it is a convenient method, standard MagLev (i.e., where the direction of magnetization and gravitational force are parallel) cannot resolve differences in density mm) because (i) objects close in density prevent each other from reaching an equilibrium height due to hard contact and excluded volume, and (ii) using weaker magnets or reducing the magnetic susceptibility of the medium destabilizes the magnetic trap. The present work investigates the use of weak magnetic gradients parallel to the faces of the magnets as a means of increasing the sensitivity of MagLev without destabilization. Configuring the MagLev device in a rotated state (i.e., where the direction of magnetization and gravitational force are perpendicular) relative to the standard configuration enables simple measurements along the axes with the highest sensitivity to changes in density. Manipulating the distance of separation between the magnets or the lengths of the magnets (along the axis of measurement) enables the sensitivity to be tuned. These modifications enable an improvement in the resolution up to 100-fold over the standard configuration, and measurements with resolution down to 10(-6) g/cm(3). Three examples of characterizing the small differences in density among samples of materials having ostensibly indistinguishable densities-Nylon spheres, PMMA spheres, and drug spheres-demonstrate the applicability of rotated Maglev to measuring the density of small (0.1-1 mm) objects with high sensitivity. This capability will be useful in materials science, separations, and quality control of manufactured objects.

  8. Calibration and Collaboration: Important Tools to Design high-Performance Affordable Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Wei; Liu, Bing; Snell, John; Helmes, Dan

    2008-03-31

    When new technologies are installed in a building, it is difficult to know how various systems will interact and if the building will perform as well as expected. A widely used technique to verify and quantify the actual energy savings from the energy-efficient features in high-performance buildings is to use the calibrated energy simulation approach. Maverick Gardens Mid-Rise A is a six-story apartment building located in East Boston, Massachusetts. The building was designed and constructed to meet the ENERGY STAR Homes Program rating and the U.S. Green Building Council’s Leadership in Energy and Environmental Design (LEED) certification. During the design phase, DOE-2.1E energy models for both budget building design and proposed building design were developed by the design team to demonstrate energy savings potential from various energy efficient technologies installed in this high-performance building. When comparing the energy use predicted by the proposed design energy model with utility bills, the design team observed that this building’s actual energy consumption was about one-third of what was estimated from the proposed design model, and therefore requested help from the authors through the U.S. Department of Energy’s Rebuild America Program to calibrate the proposed design energy model. This paper describes the energy simulation calibration approach using short-term metering data and utility bills. Details of the analysis, calibration results and the actual building energy performance are presented. This study also discusses lessons learned during the simulation calibration process and demonstrates the importance of collaboration among design professionals throughout the design, building, and commissioning process, as a way to ensure that high-performing building goals are met.

  9. High pressure-sensitive gene expression in Lactobacillus sanfranciscensis

    Directory of Open Access Journals (Sweden)

    R.F. Vogel

    2005-08-01

    Full Text Available Lactobacillus sanfranciscensis is a Gram-positive lactic acid bacterium used in food biotechnology. It is necessary to investigate many aspects of a model organism to elucidate mechanisms of stress response, to facilitate preparation, application and performance in food fermentation, to understand mechanisms of inactivation, and to identify novel tools for high pressure biotechnology. To investigate the mechanisms of the complex bacterial response to high pressure we have analyzed changes in the proteome and transcriptome by 2-D electrophoresis, and by microarrays and real time PCR, respectively. More than 16 proteins were found to be differentially expressed upon high pressure stress and were compared to those sensitive to other stresses. Except for one apparently high pressure-specific stress protein, no pressure-specific stress proteins were found, and the proteome response to pressure was found to differ from that induced by other stresses. Selected pressure-sensitive proteins were partially sequenced and their genes were identified by reverse genetics. In a transcriptome analysis of a redundancy cleared shot gun library, about 7% of the genes investigated were found to be affected. Most of them appeared to be up-regulated 2- to 4-fold and these results were confirmed by real time PCR. Gene induction was shown for some genes up-regulated at the proteome level (clpL/groEL/rbsK, while the response of others to high hydrostatic pressure at the transcriptome level seemed to differ from that observed at the proteome level. The up-regulation of selected genes supports the view that the cell tries to compensate for pressure-induced impairment of translation and membrane transport.

  10. Rituximab induction therapy in highly sensitized kidney transplant recipients

    Institute of Scientific and Technical Information of China (English)

    YIN Hang; WAN Hao; HU Xiao-peng; LI Xiao-bei; WANG Wei; LIU Hang; REN Liang; ZHANG Xiao-dong

    2011-01-01

    Background The number of highly sensitized patients is rising, and sensitization can lead to renal transplant failure.The present study aimed to investigate the safety and efficacy of renal transplantation following induction therapy with rituximab in highly sensitized kidney transplant recipients.Methods Seven highly sensitized kidney transplant recipients who underwent rituximab therapy from December 2008 to December 2009 were retrospectively analyzed. There were 3 men and 4 women, with a mean age of 38.5 years (range, 21-47 years). The duration of hemodialysis was 3-12 months, with a mean duration of 11 months. For 4 patients,this was the second transplant; the previous graft survival time was 2-11 years, with a mean survival time of 5.8 years. All the female recipients had history of multiple pregnancies, and all patients had previously received blood transfusions. All donors were men, with a mean age of 32.5 years (range, 25-37 years). In 2 of the 7 patients, both class I and class II of panel reactive antibody were high; the remaining 5 patients showed either high in class I or in class II of panel reactive antibody. The mean panel reactive antibody value was 31% for class I and 51% for class II respectively. The donors and the recipients had the same blood type, with low lymphocyte cytotoxicity ranging from 2% to 5%. The human leukocyte antigen (HLA) mismatch numbers were from 2 to 4. All patients received tacrolimus (0.1 mg·kg-1·d-1) and mycophenolate mofetil (750 mg twice per day) orally 3 days prior to surgery. All patients received a single dose of 600 mg rituximab (375 mg/m2) infusion on the day before surgery and polyclonal antibody (antithymocyte globulin) on the day of surgery.Postoperative creatinine, creatinine clearance rate, and occurrence of rejection by pathological biopsy confirmation were monitored.Results No patient had delayed graft function after surgery. Two patients had acute rejection, one on day 7 and the other on day 13 post

  11. Highly sensitive detection of Staphylococcus aureus directly from patient blood.

    Directory of Open Access Journals (Sweden)

    Padmapriya P Banada

    Full Text Available BACKGROUND: Rapid detection of bloodstream infections (BSIs can be lifesaving. We investigated the sample processing and assay parameters necessary for highly-sensitive detection of bloodstream bacteria, using Staphylococcus aureus as a model pathogen and an automated fluidic sample processing-polymerase chain reaction (PCR platform as a model diagnostic system. METHODOLOGY/PRINCIPAL FINDINGS: We compared a short 128 bp amplicon hemi-nested PCR and a relatively shorter 79 bp amplicon nested PCR targeting the S. aureus nuc and sodA genes, respectively. The sodA nested assay showed an enhanced limit of detection (LOD of 5 genomic copies per reaction or 10 colony forming units (CFU per ml blood over 50 copies per reaction or 50 CFU/ml for the nuc assay. To establish optimal extraction protocols, we investigated the relative abundance of the bacteria in different components of the blood (white blood cells (WBCs, plasma or whole blood, using the above assays. The blood samples were obtained from the patients who were culture positive for S. aureus. Whole blood resulted in maximum PCR positives with sodA assay (90% positive as opposed to cell-associated bacteria (in WBCs (71% samples positive or free bacterial DNA in plasma (62.5% samples positive. Both the assays were further tested for direct detection of S. aureus in patient whole blood samples that were contemporaneous culture positive. S. aureus was detected in 40/45 of culture-positive patients (sensitivity 89%, 95% CI 0.75-0.96 and 0/59 negative controls with the sodA assay (specificity 100%, 95% CI 0.92-1. CONCLUSIONS: We have demonstrated a highly sensitive two-hour assay for detection of sepsis causing bacteria like S. aureus directly in 1 ml of whole blood, without the need for blood culture.

  12. Uptilted Macros as an Outdoor Solution for Indoor Users in High Rise Buildings

    DEFF Research Database (Denmark)

    Sanchez, Maria Laura Luque; Vejlgaard, Benny; Mogensen, Preben

    2015-01-01

    With an expected broadband traffic volume growth of 1000x in the coming years, the need to provide coverage and capacity to the high rise buildings scenarios becomes a challenge for operators. Due to the difficulties in deploying their networks inside buildings, an outdoor alternative is needed. ...

  13. High-Performance Buildings – Value, Messaging, Financial and Policy Mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    McCabe, Molly

    2011-02-22

    At the request of the Pacific Northwest National Laboratory, an in-depth analysis of the rapidly evolving state of real estate investments, high-performance building technology, and interest in efficiency was conducted by HaydenTanner, LLC, for the U.S. Department of Energy (DOE) Building Technologies Program. The analysis objectives were • to evaluate the link between high-performance buildings and their market value • to identify core messaging to motivate owners, investors, financiers, and others in the real estate sector to appropriately value and deploy high-performance strategies and technologies across new and existing buildings • to summarize financial mechanisms that facilitate increased investment in these buildings. To meet these objectives, work consisted of a literature review of relevant writings, examination of existing and emergent financial and policy mechanisms, interviews with industry stakeholders, and an evaluation of the value implications through financial modeling. This report documents the analysis methodology and findings, conclusion and recommendations. Its intent is to support and inform the DOE Building Technologies Program on policy and program planning for the financing of high-performance new buildings and building retrofit projects.

  14. A wearable and highly sensitive pressure sensor with ultrathin gold nanowires

    Science.gov (United States)

    Gong, Shu; Schwalb, Willem; Wang, Yongwei; Chen, Yi; Tang, Yue; Si, Jye; Shirinzadeh, Bijan; Cheng, Wenlong

    2014-02-01

    Ultrathin gold nanowires are mechanically flexible yet robust, which are novel building blocks with potential applications in future wearable optoelectronic devices. Here we report an efficient, low-cost fabrication strategy to construct a highly sensitive, flexible pressure sensor by sandwiching ultrathin gold nanowire-impregnated tissue paper between two thin polydimethylsiloxane sheets. The entire device fabrication process is scalable, enabling facile large-area integration and patterning for mapping spatial pressure distribution. Our gold nanowires-based pressure sensors can be operated at a battery voltage of 1.5 V with low energy consumption (1.14 kPa-1) and high stability (>50,000 loading-unloading cycles). In addition, our sensor can resolve pressing, bending, torsional forces and acoustic vibrations. The superior sensing properties in conjunction with mechanical flexibility and robustness enabled real-time monitoring of blood pulses as well as detection of small vibration forces from music.

  15. Coumarin-bearing triarylamine sensitizers with high molar extinction coefficient for dye-sensitized solar cells

    Science.gov (United States)

    Zhong, Changjian; Gao, Jianrong; Cui, Yanhong; Li, Ting; Han, Liang

    2015-01-01

    Coumarin unit is introduced into triarylamine and three organic sensitizers are designed and synthesized with triarylamine bearing coumarin moiety as the electron donor, conjugated system containing thiophene unit as the π-bridge, and cyanoacetic acid moiety as the electron acceptor. The light-harvesting capabilities and photovoltaic performance of these dyes are investigated systematically with the comparison of different π-bridges. High molar extinction coefficients are observed in these triarylamine dyes and the photocurrent and photovoltage are increased with the introduction of another thiophene or benzene. Optimal photovoltaic performance (η = 6.24%, Voc = 690 mV, Jsc = 14.33 mA cm-2, and ff = 0.63) is observed in the DSSC based on dye with thiophene-phenyl unit as the π-conjugated bridge under 100 mW cm-2 simulated AM 1.5 G solar irradiation.

  16. Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment.

    Science.gov (United States)

    Klaus, Joseph P; Botten, Jason

    2016-03-02

    Arenaviruses are a family of enveloped RNA viruses that cause severe human disease. The first step in the arenavirus life cycle is attachment of viral particles to host cells. While virus-cell attachment can be measured through the use of virions labeled with biotin, radioactive isotopes, or fluorescent dyes, these approaches typically require high multiplicities of infection (MOI) to enable detection of bound virus. We describe a quantitative (q)RT-PCR-based assay that measures Junin virus strain Candid 1 attachment via quantitation of virion-packaged viral genomic RNA. This assay has several advantages including its extreme sensitivity and ability to measure attachment over a large dynamic range of MOIs without the need to purify or label input virus. Importantly, this approach can be easily tailored for use with other viruses through the use of virus-specific qRT-PCR reagents. Further, this assay can be modified to permit measurement of particle endocytosis and genome uncoating. In conclusion, we describe a simple, yet robust assay for highly sensitive measurement of arenavirus-cell attachment.

  17. A highly sensitive method for quantification of iohexol

    DEFF Research Database (Denmark)

    Schulz, A.; Boeringer, F.; Swifka, J.

    2014-01-01

    lohexol (1-N,3-N-bis(2,3-dihydroxypropyl)-5-IN-(2,3-dihydroxypropyl) acetamide-2,4,6-triiodobenzene1,3-dicarboxamide) is used for accurate determination of the glomerular filtration rate (GFR) in chronic kidney disease (CKD) patients. However, high iohexol amounts might lead to adverse effects in...... in organisms. In order to minimize the iohexol dosage required for the GFR determination in humans, the development of a sensitive quantification method is essential. Therefore, the objective of our preclinical study was to establish and validate a simple and robust liquid...... with a cut-off of 3 kDa. The chromatographic separation was achieved on an analytical Zorbax SB C18 column. The detection and quantification were performed on a high capacity trap mass spectrometer using positive ion ESI in the multiple reaction monitoring (MRM) mode. Furthermore, using real-time polymerase...

  18. Sensitivity study of reliable, high-throughput resolution metricsfor photoresists

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Christopher N.; Naulleau, Patrick P.

    2007-07-30

    The resolution of chemically amplified resists is becoming an increasing concern, especially for lithography in the extreme ultraviolet (EUV) regime. Large-scale screening and performance-based down-selection is currently underway to identify resist platforms that can support shrinking feature sizes. Resist screening efforts, however, are hampered by the absence of reliable resolution metrics that can objectively quantify resist resolution in a high-throughput fashion. Here we examine two high-throughput metrics for resist resolution determination. After summarizing their details and justifying their utility, we characterize the sensitivity of both metrics to two of the main experimental uncertainties associated with lithographic exposure tools, namely: limited focus control and limited knowledge of optical aberrations. For an implementation at EUV wavelengths, we report aberration and focus limited error bars in extracted resolution of {approx} 1.25 nm RMS for both metrics making them attractive candidates for future screening and down-selection efforts.

  19. Correcting systematic errors in high-sensitivity deuteron polarization measurements

    Energy Technology Data Exchange (ETDEWEB)

    Brantjes, N.P.M. [Kernfysisch Versneller Instituut, University of Groningen, NL-9747AA Groningen (Netherlands); Dzordzhadze, V. [Brookhaven National Laboratory, Upton, NY 11973 (United States); Gebel, R. [Institut fuer Kernphysik, Juelich Center for Hadron Physics, Forschungszentrum Juelich, D-52425 Juelich (Germany); Gonnella, F. [Physica Department of ' Tor Vergata' University, Rome (Italy); INFN-Sez. ' Roma tor Vergata,' Rome (Italy); Gray, F.E. [Regis University, Denver, CO 80221 (United States); Hoek, D.J. van der [Kernfysisch Versneller Instituut, University of Groningen, NL-9747AA Groningen (Netherlands); Imig, A. [Brookhaven National Laboratory, Upton, NY 11973 (United States); Kruithof, W.L. [Kernfysisch Versneller Instituut, University of Groningen, NL-9747AA Groningen (Netherlands); Lazarus, D.M. [Brookhaven National Laboratory, Upton, NY 11973 (United States); Lehrach, A.; Lorentz, B. [Institut fuer Kernphysik, Juelich Center for Hadron Physics, Forschungszentrum Juelich, D-52425 Juelich (Germany); Messi, R. [Physica Department of ' Tor Vergata' University, Rome (Italy); INFN-Sez. ' Roma tor Vergata,' Rome (Italy); Moricciani, D. [INFN-Sez. ' Roma tor Vergata,' Rome (Italy); Morse, W.M. [Brookhaven National Laboratory, Upton, NY 11973 (United States); Noid, G.A. [Indiana University Cyclotron Facility, Bloomington, IN 47408 (United States); and others

    2012-02-01

    This paper reports deuteron vector and tensor beam polarization measurements taken to investigate the systematic variations due to geometric beam misalignments and high data rates. The experiments used the In-Beam Polarimeter at the KVI-Groningen and the EDDA detector at the Cooler Synchrotron COSY at Juelich. By measuring with very high statistical precision, the contributions that are second-order in the systematic errors become apparent. By calibrating the sensitivity of the polarimeter to such errors, it becomes possible to obtain information from the raw count rate values on the size of the errors and to use this information to correct the polarization measurements. During the experiment, it was possible to demonstrate that corrections were satisfactory at the level of 10{sup -5} for deliberately large errors. This may facilitate the real time observation of vector polarization changes smaller than 10{sup -6} in a search for an electric dipole moment using a storage ring.

  20. High Sensitivity MEMS Strain Sensor: Design and Simulation

    Directory of Open Access Journals (Sweden)

    Edmond Lou

    2008-04-01

    Full Text Available In this article, we report on the new design of a miniaturized strain microsensor. The proposed sensor utilizes the piezoresistive properties of doped single crystal silicon. Employing the Micro Electro Mechanical Systems (MEMS technology, high sensor sensitivities and resolutions have been achieved. The current sensor design employs different levels of signal amplifications. These amplifications include geometric, material and electronic levels. The sensor and the electronic circuits can be integrated on a single chip, and packaged as a small functional unit. The sensor converts input strain to resistance change, which can be transformed to bridge imbalance voltage. An analog output that demonstrates high sensitivity (0.03mV/me, high absolute resolution (1μe and low power consumption (100μA with a maximum range of ±4000μe has been reported. These performance characteristics have been achieved with high signal stability over a wide temperature range (±50oC, which introduces the proposed MEMS strain sensor as a strong candidate for wireless strain sensing applications under harsh environmental conditions. Moreover, this sensor has been designed, verified and can be easily modified to measure other values such as force, torque…etc. In this work, the sensor design is achieved using Finite Element Method (FEM with the application of the piezoresistivity theory. This design process and the microfabrication process flow to prototype the design have been presented.

  1. Data of cost-optimality and technical solutions for high energy performance buildings in warm climate.

    Science.gov (United States)

    Zacà, Ilaria; D'Agostino, Delia; Maria Congedo, Paolo; Baglivo, Cristina

    2015-09-01

    The data reported in this article refers to input and output information related to the research articles entitled Assessment of cost-optimality and technical solutions in high performance multi-residential buildings in the Mediterranean area by Zacà et al. (Assessment of cost-optimality and technical solutions in high performance multi-residential buildings in the Mediterranean area, in press.) and related to the research article Cost-optimal analysis and technical comparison between standard and high efficient mono residential buildings in a warm climate by Baglivo et al. (Energy, 2015, 10.1016/j.energy.2015.02.062, in press).

  2. High-performance thermoelectric nanocomposites from nanocrystal building blocks.

    Science.gov (United States)

    Ibáñez, Maria; Luo, Zhishan; Genç, Aziz; Piveteau, Laura; Ortega, Silvia; Cadavid, Doris; Dobrozhan, Oleksandr; Liu, Yu; Nachtegaal, Maarten; Zebarjadi, Mona; Arbiol, Jordi; Kovalenko, Maksym V; Cabot, Andreu

    2016-01-01

    The efficient conversion between thermal and electrical energy by means of durable, silent and scalable solid-state thermoelectric devices has been a long standing goal. While nanocrystalline materials have already led to substantially higher thermoelectric efficiencies, further improvements are expected to arise from precise chemical engineering of nanoscale building blocks and interfaces. Here we present a simple and versatile bottom-up strategy based on the assembly of colloidal nanocrystals to produce consolidated yet nanostructured thermoelectric materials. In the case study on the PbS-Ag system, Ag nanodomains not only contribute to block phonon propagation, but also provide electrons to the PbS host semiconductor and reduce the PbS intergrain energy barriers for charge transport. Thus, PbS-Ag nanocomposites exhibit reduced thermal conductivities and higher charge carrier concentrations and mobilities than PbS nanomaterial. Such improvements of the material transport properties provide thermoelectric figures of merit up to 1.7 at 850 K.

  3. High Strength Phosphogypsum and Its Use as a Building Material

    Science.gov (United States)

    Kanno, Wellington Massayuki; Rossetto, Hebert Luis; de Souza, Milton Ferreira; Máduar, Marcelo Francis; de Campos, Marcia Pires; Mazzilli, Barbara Paci

    2008-08-01

    A new process (patent applied) that works equally well with both plaster of mineral gypsum and phosphogypsum for the preparation of gypsum components, UCOS, has been developed. The process consists of the following steps: humidification of plaster by fine water droplets, uni-axial compression, hydration reaction and drying. Strong hydrogen bonds develop among the crystals together with adhesion provided by confined water that accounts for nearly 70% of the adhesion forces. By reducing the plaster to water ratio to close the minimum necessary, new features are generated. An experimental house has been constructed, in which walls and ceilings have been built of gypsum and phosphogypsum. Since phosphogypsum potentially contain radioactive elements, the application of an activity concentration index to the phosphogypsum employed in the building was carried out.

  4. A high-speed DAQ framework for future high-level trigger and event building clusters

    Science.gov (United States)

    Caselle, M.; Ardila Perez, L. E.; Balzer, M.; Dritschler, T.; Kopmann, A.; Mohr, H.; Rota, L.; Vogelgesang, M.; Weber, M.

    2017-03-01

    Modern data acquisition and trigger systems require a throughput of several GB/s and latencies of the order of microseconds. To satisfy such requirements, a heterogeneous readout system based on FPGA readout cards and GPU-based computing nodes coupled by InfiniBand has been developed. The incoming data from the back-end electronics is delivered directly into the internal memory of GPUs through a dedicated peer-to-peer PCIe communication. High performance DMA engines have been developed for direct communication between FPGAs and GPUs using "DirectGMA (AMD)" and "GPUDirect (NVIDIA)" technologies. The proposed infrastructure is a candidate for future generations of event building clusters, high-level trigger filter farms and low-level trigger system. In this paper the heterogeneous FPGA-GPU architecture will be presented and its performance be discussed.

  5. High concentrations of radon. Specifically affected buildings; Hohe Radonkonzentrationen. Besonders betroffene Gebaeudetypen

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Winfried [Bundesamt fuer Strahlenschutz, Berlin (Germany)

    2015-07-01

    The paper presents a concept for the prognosis of exceeding probabilities of thresholds of radon in dwellings in different building types. A transfer model for the interface subsoil - building was used as a basis. The partial datasets obtained by stratification of five relevant building characteristics can be de-scribed by a 3-parametric-lognormal distribution good in most times. The available data permit statistical predictions to 60 combinations of building characteristics for the region ''east'' and 85 combinations of building characteristics for the region ''West''. The uncertainties for the probability of exceeding a threshold were estimated from the data with bootstrapping. The importance of different building characteristics for the presence of enhanced radon concentrations can be predicted from the results of this estimation. Therefore, targeting of affected buildings is possible on this basis. Regional prognoses of exceeding probabilities for building types with high presence can also be created by the use of transfer factors. A Strategy to reduce the health risk from radon in the long run might be derived, where alongside the delineation of radon prone areas, special attention should be paid to a set out building characteristics, also outside the radon prone areas.

  6. Highly sensitive flow-injection chemiluminescence determination of pyrogallol compounds

    Science.gov (United States)

    Kanwal, Shamsa; Fu, Xiaohong; Su, Xingguang

    2009-12-01

    A highly sensitive flow-injection chemiluminescent method for the direct determination of pyrogallol compounds has been developed. Proposed method is based on the enhanced effect of pyrogallol compounds on the chemiluminescence signals of KMnO 4-H 2O 2 system in slightly alkaline medium. Three important pyrogallol compounds, pyrogallic acid, gallic acid and tannic acid, have been detected by this method, and the possible mechanism of the CL reaction is also discussed. The proposed method is simple, convenient, rapid (60 samples h -1), and sensitive, has a linear range of 8 × 10 -10 mol L -1 to 1 × 10 -5 mol L -1, for pyrogallic acid, with a detection limit of 6 × 10 -11 mol L -1, 4 × 10 -8 mol L -1 to 5 × 10 -3 mol L -1 for gallic acid with a detection limit of 9 × 10 -10 mol L -1, and 8 × 10 -8 mol L -1 to 5 × 10 -2 mol L -1 for tannic acid, with a detection limit of 2 × 10 -9 mol L -1, respectively. The relative standard deviation (RSD, n = 15) was 0.8, 1.1 and 1.3% for 5 × 10 -6 mol L -1 pyrogallic acid, gallic acid and tannic acid, respectively. The proposed method was successfully applied to the determination of pyrogallol compounds in tea and coffee samples.

  7. PlanetPol: A Very High Sensitivity Polarimeter

    Science.gov (United States)

    Hough, J. H.; Lucas, P. W.; Bailey, J. A.; Tamura, M.; Hirst, E.; Harrison, D.; Bartholomew-Biggs, M.

    2006-09-01

    We have built and used on several occasions an optical broadband stellar polarimeter, PlanetPol, which employs photoelastic modulators and avalanche photodiodes and achieves a photon-noise-limited sensitivity of at least 1 in 106 in fractional polarization. Observations of a number of polarized standards taken from the literature show that the accuracy of polarization measurements is ~1%. We have developed a method for accurately measuring the polarization of altitude-azimuth mounted telescopes by observing bright nearby stars at different parallactic angles, and we find that the on-axis polarization of the William Herschel Telescope is typically ~15 × 10-6, measured with an accuracy of a few parts in 107. The nearby stars (distance less than 32 pc) are found to have very low polarizations, typically a few ×10-6, indicating that very little interstellar polarization is produced close to the Sun and that their intrinsic polarization is also low. Although the polarimeter can be used for a wide range of astronomy, the very high sensitivity was set by the goal of detecting the polarization signature of unresolved extrasolar planets.

  8. Kinetics of Highly Sensitive Troponin T after Cardiac Surgery

    Directory of Open Access Journals (Sweden)

    Amr S. Omar

    2015-01-01

    Full Text Available Perioperative myocardial infarction (PMI confers a considerable risk in cardiac surgery settings; finding the ideal biomarker seems to be an ideal goal. Our aim was to assess the diagnostic accuracy of highly sensitive troponin T (hsTnT in cardiac surgery settings and to define a diagnostic level for PMI diagnosis. This was a single-center prospective observational study analyzing data from all patients who underwent cardiac surgeries. The primary outcome was the diagnosis of PMI through a specific level. The secondary outcome measures were the lengths of mechanical ventilation (LOV, stay in the intensive care unit (LOSICU, and hospitalization. Based on the third universal definition of PMI, patients were divided into two groups: no PMI (Group I and PMI (Group II. Data from 413 patients were analyzed. Nine patients fulfilled the diagnostic criteria of PMI, while 41 patients were identified with a 5-fold increase in their CK-MB (≥120 U/L. Using ROC analysis, a hsTnT level of 3,466 ng/L or above showed 90% sensitivity and 90% specificity for the diagnosis of PMI. Secondary outcome measures in patients with PMI were significantly prolonged. In conclusion, the hsTnT levels detected here paralleled those of CK-MB and a cut-off level of 3466 ng/L could be diagnostic of PMI.

  9. Development of a New, High Sensitivity 2000 kg Mechanical Balance.

    Science.gov (United States)

    Wang, Jian

    2017-04-13

    Mass measurement of more than 500 kg on an electronic mass comparator has no better repeatability and linearity of measurement for meeting the calibration requirement of over class F1 weights from pharmacy and power generation plants. For this purpose, a new 2000 kg mechanical balance was developed by the National Institute of Metrology (NIM). The advantages of measurement of more than 500 kg on a new 2000 kg mechanical balance are introduced in the paper. In order to obtain high measurement uncertainty, four vertical forces of two sides of beam are measured and used as reference for adjustment of the beam position. Laser displacement sensors in the indication system are more effective for decreasing reading errors caused by human vision. To improve the repeatability and sensitivity of the equipment, a synchronous lifting control is designed for synchronously lifting the beam ends along the vertical direction. A counterweight selection system is developed to get any combination of weights in a limited space. The sensitivity of the new mechanical balance for 2000 kg is more than 1.7 parts in 10(-4) rad/g. The extended uncertainties for the mechanical balance of 500 kg, 1000 kg and 2000 kg are 0.47 g, 1.8 g and 3.5 g respectively.

  10. New application of superconductors: High sensitivity cryogenic light detectors

    Science.gov (United States)

    Cardani, L.; Bellini, F.; Casali, N.; Castellano, M. G.; Colantoni, I.; Coppolecchia, A.; Cosmelli, C.; Cruciani, A.; D'Addabbo, A.; Di Domizio, S.; Martinez, M.; Tomei, C.; Vignati, M.

    2017-02-01

    In this paper we describe the current status of the CALDER project, which is developing ultra-sensitive light detectors based on superconductors for cryogenic applications. When we apply an AC current to a superconductor, the Cooper pairs oscillate and acquire kinetic inductance, that can be measured by inserting the superconductor in a LC circuit with high merit factor. Interactions in the superconductor can break the Cooper pairs, causing sizable variations in the kinetic inductance and, thus, in the response of the LC circuit. The continuous monitoring of the amplitude and frequency modulation allows to reconstruct the incident energy with excellent sensitivity. This concept is at the basis of Kinetic Inductance Detectors (KIDs) that are characterized by natural aptitude to multiplexed read-out (several sensors can be tuned to different resonant frequencies and coupled to the same line), resolution of few eV, stable behavior over a wide temperature range, and ease in fabrication. We present the results obtained by the CALDER collaboration with 2×2 cm2 substrates sampled by 1 or 4 Aluminum KIDs. We show that the performances of the first prototypes are already competitive with those of other commonly used light detectors, and we discuss the strategies for a further improvement.

  11. A highly sensitive fiber Bragg grating diaphragm pressure transducer

    Science.gov (United States)

    Allwood, Gary; Wild, Graham; Lubansky, Alex; Hinckley, Steven

    2015-10-01

    In this work, a novel diaphragm based pressure transducer with high sensitivity is described, including the physical design structure, in-depth analysis of optical response to changes in pressure, and a discussion of practical implementation and limitations. A flat circular rubber membrane bonded to a cylinder forms the body of the transducer. A fiber Bragg grating bonded to the center of the diaphragm structure enables the fractional change in pressure to be determined by analyzing the change in Bragg wavelength of the reflected spectra. Extensive evaluation of the physical properties and optical characteristics of the transducer has been performed through experimentation, and modeling using small deformation theory. The results show the transducer has a sensitivity of 0.116 nm/kPa, across a range of 15 kPa. Ultra-low cost interrogation of the optical signal was achieved through the use of an optically mismatched Bragg grating acting as an edge filter to convert the spectral change into an intensity change. A numerical model of the intensity based interrogation was implemented in order to validate the experimental results. Utilizing this interrogation technique and housing both the sensing and reference Bragg gratings within the main body of the transducer means it is effectively temperature insensitive and easily connected to electronic systems.

  12. Sensitivity of once-shocked, weathered high explosives

    Energy Technology Data Exchange (ETDEWEB)

    Williams, K.L.; Harris, B.W.

    1998-07-01

    Effects caused by stimulating once-shocked, weathered high explosives (OSW-HE) are investigated. The sensitivity of OSW-HE to mechanical stimuli was determined using standard industry tests. Some initial results are given. Pieces of OSW-HE were collected from active and inactive firing sites and from an area surrounding a drop tower at Los Alamos where skid and spigot tests were done. Samples evaluated were cast explosives or plastic bonded explosive (PBX) formulations containing cyclotrimethylenetrinitramine (RDX), cyclotetramethylene tetranitramine (HMX), 2,4,6-trinitrotoluene (TNT), mock or inert HE [tris(beta-chloroethyl)phosphate (CEF)], barium nitrate, cyanuric acid, talc, and Kel-F. Once-shocked, weathered LX-10 Livermore explosive [HMX/Viton A, (95/5 wt %)], PBX 9011 [HMX/Estane, (90/10 wt %)], PBX 9404 [HMX/nitrocellulose, tris(beta-chloroethyl) phosphate, (94/3/3 wt %)], Composition B or cyclotol (TNT/RDX explosives), and PBX 9007 (90% RDX, 9.1% styrene, 0.5% dioctyl phthalate, and 0.45 resin) were subjected to the hammer test, the drop-weight impact sensitivity test, differential thermal analysis (DTA), the spark test, the Henkin`s critical temperature test, and the flame test. Samples were subjected to remote, wet cutting and drilling; remote, liquid-nitrogen-cooled grinding and crushing; and scanning electron microscope (SEM) surface analyses for morphological changes.

  13. Luminescent Lanthanide Reporters for High-Sensitivity Novel Bioassays.

    Energy Technology Data Exchange (ETDEWEB)

    Anstey, Mitchell R.; Fruetel, Julia A.; Foster, Michael E.; Hayden, Carl C.; Buckley, Heather L.; Arnold, John

    2013-09-01

    Biological imaging and assay technologies rely on fluorescent organic dyes as reporters for a number of interesting targets and processes. However, limitations of organic dyes such as small Stokes shifts, spectral overlap of emission signals with native biological fluorescence background, and photobleaching have all inhibited the development of highly sensitive assays. To overcome the limitations of organic dyes for bioassays, we propose to develop lanthanide-based luminescent dyes and demonstrate them for molecular reporting applications. This relatively new family of dyes was selected for their attractive spectral and chemical properties. Luminescence is imparted by the lanthanide atom and allows for relatively simple chemical structures that can be tailored to the application. The photophysical properties offer unique features such as narrow and non-overlapping emission bands, long luminescent lifetimes, and long wavelength emission, which enable significant sensitivity improvements over organic dyes through spectral and temporal gating of the luminescent signal.Growth in this field has been hindered due to the necessary advanced synthetic chemistry techniques and access to experts in biological assay development. Our strategy for the development of a new lanthanide-based fluorescent reporter system is based on chelation of the lanthanide metal center using absorbing chromophores. Our first strategy involves "Click" chemistry to develop 3-fold symmetric chelators and the other involves use of a new class of tetrapyrrole ligands called corroles. This two-pronged approach is geared towards the optimization of chromophores to enhance light output.

  14. A Metal-Organic Framework Containing Unusual Eight-Connected Zr–-Oxo Secondary Building Units and Orthogonal Carboxylic Acids for Ultra-sensitive Metal Detection

    Energy Technology Data Exchange (ETDEWEB)

    Carboni, Michaël; Lin, Zekai; Abney, Carter W.; Zhang, Teng; Lin, Wenbin (UC)

    2015-08-21

    Two metal-organic frameworks (MOFs) with Zr-oxo secondary building units (SBUs) were prepared by using p,p'-terphenyldicarboxylate (TPDC) bridging ligands pre-functionalized with orthogonal succinic acid (MOF-1) and maleic acid groups (MOF-2). Single-crystal X-ray structure analysis of MOF-1 provides the first direct evidence for eight-connected SBUs in UiO-type MOFs. In contrast, MOF-2 contains twelve-connected SBUs as seen in the traditional UiO MOF topology. These structural assignments were confirmed by extended X-ray absorption fine structure (EXAFS) analysis. The highly porous MOF-1 is an excellent fluorescence sensor for metal ions with the detection limit of <0.5 ppb for Mn2+ and three to four orders of magnitude greater sensitivity for metal ions than previously reported luminescent MOFs.

  15. Computer aided seismic and fire retrofitting analysis of existing high rise reinforced concrete buildings

    CERN Document Server

    Hussain, Raja Rizwan; Hasan, Saeed

    2016-01-01

    This book details the analysis and design of high rise buildings for gravity and seismic analysis. It provides the knowledge structural engineers need to retrofit existing structures in order to meet safety requirements and better prevent potential damage from such disasters as earthquakes and fires. Coverage includes actual case studies of existing buildings, reviews of current knowledge for damages and their mitigation, protective design technologies, and analytical and computational techniques. This monograph also provides an experimental investigation on the properties of fiber reinforced concrete that consists of natural fibres like coconut coir and also steel fibres that are used for comparison in both Normal Strength Concrete (NSC) and High Strength Concrete (HSC). In addition, the authors examine the use of various repair techniques for damaged high rise buildings. The book will help upcoming structural design engineers learn the computer aided analysis and design of real existing high rise buildings ...

  16. Using wind turbines in high-rise buildings in the development of ...

    African Journals Online (AJOL)

    Using wind turbines in high-rise buildings in the development of sustainable ... The increasing consumption of fossil fuels as limited sources of energy and its ... to maintain the environmental and energy efficiency leads to better planning for ...

  17. Fuzzy-AHP-Based Comprehensive Evaluation on Facility Management System of High-Rise Office Buildings

    Institute of Scientific and Technical Information of China (English)

    ZHANG Peihong; WANG Kan; WAN Huanhuan; MA Zhongjiao

    2011-01-01

    The present building facility management status in China resulted in many problems such as highenergy consumption, failure of automation control, services failure and poor indoor air quality. Based onquestionnaires and interviews to professional engineers and building users, a comprehensive evaluation index system was established on facility management of high-rise office buildings. A Fuzzy AHP based upon hierarchy criteria system was established. A Fuzzy AHP Evaluation Model on Facility Management System was set up ;α-cut analysis was introduced and incorporated with expert knowledge together, which made up the optimism index λ. The fuzzy optimum crisp weight of each criterion was resulted from data-mining. Case investigations were processed in high-rise office buildings in Shenyang. The results illustrated that indoor air quality, thermal comfort and life cycle cost were the most important indexes in the evaluation of Facility Management System of high rise office buildings. Residents in high-rise buildings in Shenyang pay less attention to maintenance management and environment protection. By comparison with the analysis result of Export Choice, Fuzzy AHP-based evaluation model could act as a scientific reference for the establishment of governmental standards in facility management area in building.

  18. Tunable diameter electrostatically formed nanowire for high sensitivity gas sensing

    Institute of Scientific and Technical Information of China (English)

    Alex Henning; Nandhini Swaminathan; Andrey Godkin; Gil Shalev; Iddo Amit; Yossi Rosenwaks

    2015-01-01

    We report on an electrostatically formed nanowire (EFN)-based sensor with tunable diameters in the range of 16 nm to 46 nm and demonstrate an EFN- based field-effect transistor as a highly sensitive and robust room temperature gas sensor. The device was carefully designed and fabricated using standard integrated processing to achieve the 16 nm EFN that can be used for sensing without any need for surface modification. The effective diameter for the EFN was determined using Kelvin probe force microscopy accompanied by three- dimensional electrostatic simulations. We show that the EFN transistor is capable of detecting 100 parts per million of ethanol gas with bare SiO2.

  19. Magnetic probe array with high sensitivity for fluctuating field.

    Science.gov (United States)

    Kanamaru, Yuki; Gota, Hiroshi; Fujimoto, Kayoko; Ikeyama, Taeko; Asai, Tomohiko; Takahashi, Tsutomu; Nogi, Yasuyuki

    2007-03-01

    A magnetic probe array is constructed to measure precisely the spatial structure of a small fluctuating field included in a strong confinement field that varies with time. To exclude the effect of the confinement field, the magnetic probes consisting of figure-eight-wound coils are prepared. The spatial structure of the fluctuating field is obtained from a Fourier analysis of the probe signal. It is found that the probe array is more sensitive to the fluctuating field with a high mode number than that with a low mode number. An experimental demonstration of the present method is attempted using a field-reversed configuration plasma, where the fluctuating field with 0.1% of the confinement field is successfully detected.

  20. High Efficiency of Dye-Sensitized Solar Cells

    Institute of Scientific and Technical Information of China (English)

    Liyuan Han

    2005-01-01

    @@ 1Introduction Much attention has been paid to the development of dye-sensitized solar cells (DSCs) during the past decade. In general, a DSC comprises a nanocrystalline titanium dioxide (TiO2) electrode modified with a dye fabricated on a transparent conducting oxide (TCO), a platinum (Pt) counter electrode, and an electrolyte solution with a dissolved iodide ion/tri-iodide ion redox couple between the electrodes. Although a DSC using black dye with high efficiency of 10.4%, which was measured by NREL(U. S. A. ), was reported by Graetzel et al. [1], the efficiency of DSCs should be further improved for practical use in comparison with silicon solar cells.

  1. High efficiency solid-state sensitized heterojunction photovoltaic device

    KAUST Repository

    Wang, Mingkui

    2010-06-01

    The high molar extinction coefficient heteroleptic ruthenium dye, NaRu(4,4′-bis(5-(hexylthio)thiophen-2-yl)-2,2′-bipyridine) (4-carboxylic acid-4′-carboxylate-2,2′-bipyridine) (NCS) 2, exhibits certified 5% electric power conversion efficiency at AM 1.5 solar irradiation (100 mW cm-2) in a solid-state dye-sensitized solar cell using 2,2′,7,7′-tetrakis-(N,N-di-pmethoxyphenylamine)-9, 9′-spirobifluorene (spiro-MeOTAD) as the organic hole-transporting material. This demonstration elucidates a class of photovoltaic devices with potential for low-cost power generation. © 2010 Elsevier Ltd. All rights reserved.

  2. High sensitivity moiré interferometry with compact achromatic interferometry

    Science.gov (United States)

    Czarnek, Robert

    Experimental observations and measurements are the sources of information essential for correct development of mathematical models of real structural materials. Moiré interferometry offers high sensitivity in full-field measurements of in-plane displacements on the surface of a specimen. Although it is a powerful method in experimental stress analysis, it has some shortcomings. One is that existing systems require highly coherent light. The only sufficient source of light for this application is a long cavity laser, which is relatively expensive and at best cumbersome. Another shortcoming is that measurements must be performed in a vibration-free environment, such as that found on a holographic table. These requirements limit the use of existing moiré interferometers to a holographic laboratory. In this paper a modified concept of compensation is presented, which permits the use of a chromatic source of light in a compact moiré system. The compensator provides order in the angles of incident light for each separate wavelength, so that the virtual reference grating created by each wavelength in a continuous spectrum is identical in frequency and spatial position. The result is a virtual reference grating that behaves exactly like that created in coherent light. With this development the use of a laser diode, which is a non-coherent light source of tiny dimensions, becomes practical. The special configuration of the optics that create the virtual grating allows its synchronization with the specimen grating and leads to an interferometer design that is relatively insensitive to the vibrations found in a mechanical testing laboratory. Sensitivity to relative motion is analyzed theoretically. This development provides the oppurtunity to apply moiré interferometry to solid mechanics problems that cannot be studied in an optics laboratory. Experimental verification of the optical concepts is provided. A compact moiré interferometer based on the presented idea was

  3. THE CHANGE IN DEFORMATION CHARACTERISTICS OF CONCRETE MONOLITHIC HIGH-RISE BUILDINGS

    Directory of Open Access Journals (Sweden)

    V. V. Punahin

    2009-03-01

    Full Text Available In the article results of studies of deformation features of concrete on actuate cement for monolithic high-altitude buildings are presented. It is shown that in construction of the high-altitude monolithic buildings in a summer period of a year one should take into account the character of changing the concrete elasticity and plasticity in time, which differs from the same indices for the concrete of normal hardening.

  4. Scanning Auger microscopy for high lateral and depth elemental sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, E., E-mail: eugenie.martinez@cea.fr [CEA, LETI, MINATEC Campus, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France); Yadav, P. [CEA, LETI, MINATEC Campus, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France); Bouttemy, M. [Institut Lavoisier de Versailles, 45 av. des Etats-Unis, 78035 Versailles Cedex (France); Renault, O.; Borowik, Ł.; Bertin, F. [CEA, LETI, MINATEC Campus, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France); Etcheberry, A. [Institut Lavoisier de Versailles, 45 av. des Etats-Unis, 78035 Versailles Cedex (France); Chabli, A. [CEA, LETI, MINATEC Campus, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France)

    2013-12-15

    Highlights: •SAM performances and limitations are illustrated on real practical cases such as the analysis of nanowires and nanodots. •High spatial elemental resolution is shown with the analysis of reference semiconducting Al{sub 0.7}Ga{sub 0.3}As/GaAs multilayers. •High in-depth elemental resolution is also illustrated. Auger depth profiling with low energy ion beams allows revealing ultra-thin layers (∼1 nm). •Analysis of cross-sectional samples is another effective approach to obtain in-depth elemental information. -- Abstract: Scanning Auger microscopy is currently gaining interest for investigating nanostructures or thin multilayers stacks developed for nanotechnologies. New generation Auger nanoprobes combine high lateral (∼10 nm), energy (0.1%) and depth (∼2 nm) resolutions thus offering the possibility to analyze the elemental composition as well as the chemical state, at the nanometre scale. We report here on the performances and limitations on practical examples from nanotechnology research. The spatial elemental sensitivity is illustrated with the analysis of Al{sub 0.7}Ga{sub 0.3}As/GaAs heterostructures, Si nanowires and SiC nanodots. Regarding the elemental in-depth composition, two effective approaches are presented: low energy depth profiling to reveal ultra-thin layers (∼1 nm) and analysis of cross-sectional samples.

  5. Laser-engraved carbon nanotube paper for instilling high sensitivity, high stretchability, and high linearity in strain sensors

    KAUST Repository

    Xin, Yangyang

    2017-06-29

    There is an increasing demand for strain sensors with high sensitivity and high stretchability for new applications such as robotics or wearable electronics. However, for the available technologies, the sensitivity of the sensors varies widely. These sensors are also highly nonlinear, making reliable measurement challenging. Here we introduce a new family of sensors composed of a laser-engraved carbon nanotube paper embedded in an elastomer. A roll-to-roll pressing of these sensors activates a pre-defined fragmentation process, which results in a well-controlled, fragmented microstructure. Such sensors are reproducible and durable and can attain ultrahigh sensitivity and high stretchability (with a gauge factor of over 4.2 × 10(4) at 150% strain). Moreover, they can attain high linearity from 0% to 15% and from 22% to 150% strain. They are good candidates for stretchable electronic applications that require high sensitivity and linearity at large strains.

  6. Evaluation of a High-Sensitivity GPS Receiver for Kinematics Application in Regions with High Shading

    Science.gov (United States)

    Suhandri, H. F.; Becker, D.; Kleusberg, A.

    2009-04-01

    GPS positioning has been very much improved with high-sensitivity GPS (HSGPS) receivers. This kind of receiver can track the signal until 20-25dB below the level of conventional receivers. Obviously, no problem occurs when GPS technology is used for air and ocean vehicles navigation; sufficient and/or redundant signals can be easily acquired due to good hemispherical signal reception. A problem arises whenever signals cannot be traced anymore, if not enough satellites are available or if there is very weak signal reception in forest areas or between buildings. Those situations cannot be avoided or eliminated in land vehicle navigation. The HSGPS technology tries to solve those problems by tracking signals below the normal signal threshold of non-HSGPS receivers. This paper discusses the two factors of availability and accuracy in the context of navigation with HSGPS receivers. In order to investigate these issues some scenarios of receivers-placing will be examined which represent various receiver environments: good hemispherical signal reception, strong signal shading environment and indoor environment. The signal availability and accuracy are investigated during observation sessions of several hours by comparing the measurements of the HSGPS receiver with the measurements of a conventional, non-HSGPS receiver. As expected, the non-HSGPS receiver yields the same level of availability as the HSGPS receiver in an environment with good hemispherical signal reception. When both receivers are located in an environment with significant signal shading, the percentage of availability will significantly decay for the non-HSGPS receiver whereas the availability of the HSGPS receiver is much less reduced. However the results from the HSGPS receiver in this case are at a significantly reduced accuracy level. The accuracy level is assessed by using three parameters: i) the difference between the C/A code and the carrier phase in order to investigate how big the multipath and

  7. Alemtuzumab induction therapy in highly sensitized kidney transplant recipients

    Institute of Scientific and Technical Information of China (English)

    L(U) Tie-ming; YANG Shun-liang; WU Wei-zhen; TAN Jian-ming

    2011-01-01

    Background Immunosuppression for immunologically high-risk kidney transplant patients usually involves antithymocyte globulin induction with triple drug maintenance therapy. Alemtuzumab, a humanized anti-CD52 antibody,was expected to be a promising induction therapy agent for kidney transplantation. However, currently no consensus is available about its efficacy and safety. This study aimed to evaluate the efficacy and safety of alemtuzumab as immune induction therapy in highly sensitized kidney transplant recipients.Methods In this prospective, open-label, randomized, controlled trial, we enrolled 23 highly immunological risk patients (panel reactive antibody >20%). They were divided into two groups: alemtuzumab group (trial group) and anti-thymocyte globulin (ATG) group (control group). Patients in the alemtuzumab group received intravenous alemtuzumab (15 mg) as a single dose before reperfusion. At the 24th hour post-operation, another dosage of alemtuzumab (15 mg) was given.The control group received a bolus of rabbit ATG (9 mg/kg), which was given 2 hours before kidney transplantation and lasted until the removal of vascular clamps when the anastomoses were completed. Maintenance immunosuppression in both groups comprised standard triple therapy consisting of tacrolimus, prednisone, and mycophenolate mofetil (MMF).Acute rejection (AR) and infection episodes were recorded, and kidney function was monitored during a 2-year follow-up.χ2 test, t test and Kaplan-Meier analysis were performed with SPSS17.0 software.Results Median follow-up was 338 days. In both the alemtuzumab group and ATG group, creatinine and blood urea nitrogen values in surviving recipients were similar (P >0.05). White blood cell counts were significantly reduced in the alemtuzumab group for the most time points up to 6 months (P <0.05). One patient receiving alemtuzumab died for acute myocardial infarction at the 65th day post-operation. Two ATG patients died for severe pulmonary

  8. Building Synergy: The Power of High Performance Work Systems.

    Science.gov (United States)

    Gephart, Martha A.; Van Buren, Mark E.

    1996-01-01

    Suggests that high-performance work systems create the synergy that lets companies gain and keep a competitive advantage. Identifies the components of high-performance work systems and critical action steps for implementation. Describes the results companies such as Xerox, Lever Brothers, and Corning Incorporated have achieved by using them. (JOW)

  9. Highly sensitive strain sensor based on helical structure combined with Mach-Zehnder interferometer in multicore fiber.

    Science.gov (United States)

    Zhang, Hailiang; Wu, Zhifang; Shum, Perry Ping; Dinh, Xuan Quyen; Low, Chun Wah; Xu, Zhilin; Wang, Ruoxu; Shao, Xuguang; Fu, Songnian; Tong, Weijun; Tang, Ming

    2017-04-18

    Optical fiber sensors for strain measurement have been playing important roles in structural health monitoring for buildings, tunnels, pipelines, aircrafts, and so on. A highly sensitive strain sensor based on helical structures (HSs) assisted Mach-Zehnder interference in an all-solid heterogeneous multicore fiber (MCF) is proposed and experimentally demonstrated. Due to the HSs, a maximum strain sensitivity as high as -61.8 pm/με was experimentally achieved. This is the highest sensitivity among interferometer-based strain sensors reported so far, to the best of our knowledge. Moreover, the proposed sensor has the ability to discriminate axial strain and temperature, and offers several advantages such as repeatability of fabrication, robust structure and compact size, which further benefits its practical sensing applications.

  10. Innovative nanostructures for highly sensitive vibrational biosensing (Conference Presentation)

    Science.gov (United States)

    Popp, Juergen; Mayerhöfer, Thomas; Cialla-May, Dana; Weber, Karina; Huebner, Uwe

    2016-03-01

    Employing vibrational spectroscopy (IR-absorption and Raman spectroscopy) allows for the labelfree detection of molecular specific fingerprints of inorganic, organic and biological substances. The sensitivity of vibrational spectroscopy can be improved by several orders of magnitude via the application of plasmonic active surfaces. Within this contribution we will discuss two such approaches, namely surface enhanced Raman spectroscopy (SERS) as well as surface enhanced IR absorption (SEIRA). It will be shown that SERS using metal colloids as SERS active substrate in combination with a microfluidic lab-on-a-chip (LOC) device enables high throughput and reproducible measurements with highest sensitivity and specificity. The application of such a LOC-SERS approach for therapeutic drug monitoring (e.g. quantitative detection of antibiotics in a urine matrix) will be presented. Furthermore, we will introduce innovative bottom-up strategies to prepare SERS-active nanostructures coated with a lipophilic sensor layer as one-time use SERS substrates for specific food analysis (e.g. quantitative detection of toxic food colorants). The second part of this contribution presents a slit array metamaterial perfect absorber for IR sensing applications consisting of a dielectric layer sandwiched between two metallic layers of which the upper layer is perforated with a periodic array of slits. Light-matter interaction is greatly amplified in the slits, where also the analyte is concentrated, as the surface of the substrate is covered by a thin silica layer. Thus, already small concentrations of analytes down to a monolayer can be detected by refractive index sensing and identified by their spectral fingerprints with a standard mid-infrared lab spectrometer.

  11. Conducting polymer nanofibers for high sensitivity detection of chemical analytes.

    Science.gov (United States)

    Kumar, Abhishek; Leshchiner, Ignaty; Nagarajan, Subhalakshmi; Nagarajan, Ramaswamy; Kumar, Jayant

    2008-03-01

    Possessing large surface area materials is vital for high sensitivity detection of analyte. We report a novel, inexpensive and simple technique to make high surface area sensing interfaces using electrospinning. Conducting polymers (CP) nanotubes were made by electrospinning a solution of a catalyst (ferric tosylate) along with poly (lactic acid), which is an environment friendly biodegradable polymer. Further vapor deposition polymerization of the monomer ethylenedioxy thiophene (EDOT) on the nanofiber surface yielded poly (EDOT) covered fibers. X-ray photo electron spectroscopy (XPS) study reveals the presence of PEDOT predominantly on the surface of nanofibers. Conducting nanotubes had been received by dissolving the polymer in the fiber core. By a similar technique we had covalently incorporated fluorescent dyes on the nanofiber surface. The materials obtained show promise as efficient sensing elements. UV-Vis characterization confirms the formation of PEDOT nanotubes and incorporation of chromophores on the fiber surface. The morphological characterization was carried out using scanning electron microscopy (SEM) and transmission electron microscopy (TEM).

  12. Accelerated Sensitivity Analysis in High-Dimensional Stochastic Reaction Networks.

    Science.gov (United States)

    Arampatzis, Georgios; Katsoulakis, Markos A; Pantazis, Yannis

    2015-01-01

    Existing sensitivity analysis approaches are not able to handle efficiently stochastic reaction networks with a large number of parameters and species, which are typical in the modeling and simulation of complex biochemical phenomena. In this paper, a two-step strategy for parametric sensitivity analysis for such systems is proposed, exploiting advantages and synergies between two recently proposed sensitivity analysis methodologies for stochastic dynamics. The first method performs sensitivity analysis of the stochastic dynamics by means of the Fisher Information Matrix on the underlying distribution of the trajectories; the second method is a reduced-variance, finite-difference, gradient-type sensitivity approach relying on stochastic coupling techniques for variance reduction. Here we demonstrate that these two methods can be combined and deployed together by means of a new sensitivity bound which incorporates the variance of the quantity of interest as well as the Fisher Information Matrix estimated from the first method. The first step of the proposed strategy labels sensitivities using the bound and screens out the insensitive parameters in a controlled manner. In the second step of the proposed strategy, a finite-difference method is applied only for the sensitivity estimation of the (potentially) sensitive parameters that have not been screened out in the first step. Results on an epidermal growth factor network with fifty parameters and on a protein homeostasis with eighty parameters demonstrate that the proposed strategy is able to quickly discover and discard the insensitive parameters and in the remaining potentially sensitive parameters it accurately estimates the sensitivities. The new sensitivity strategy can be several times faster than current state-of-the-art approaches that test all parameters, especially in "sloppy" systems. In particular, the computational acceleration is quantified by the ratio between the total number of parameters over the

  13. Lateral Load-Resisting System Using Mass Timber Panel for High-Rise Buildings

    Directory of Open Access Journals (Sweden)

    Zhiyong Chen

    2017-07-01

    Full Text Available As global interest in using engineered wood products in tall buildings intensifies due to the “green” credential of wood, it is expected that more tall wood buildings will be designed and constructed in the coming years. This, however, brings new challenges to the designers. One of the major challenges is how to design lateral load-resisting systems (LLRSs with sufficient stiffness, strength, and ductility to resist strong wind and earthquakes. In this study, an LLRS using mass timber panel on a stiff podium was developed for high-rise buildings in accordance with capacity-based design principle. The LLRS comprises eight shear walls with a core in the center of the building, which was constructed with structural composite lumber and connected with dowel-type connections and wood–steel composite system. The main energy dissipating mechanism of the LLRS was detailed to be located at the panel-to-panel interface. This LLRS was implemented in the design of a hypothetical 20-storey building. A finite element (FE model of the building was developed using general-purpose FE software, ABAQUS. The wind-induced and seismic response of the building model was investigated by performing linear static and non-linear dynamic analyses. The analysis results showed that the proposed LLRS using mass timber was suitable for high-rise buildings. This study provided a valuable insight into the structural performance of LLRS constructed with mass timber panels as a viable option to steel and concrete for high-rise buildings.

  14. Building high resolution genetic variation map for Mongolians

    DEFF Research Database (Denmark)

    Guo, Xiaosen

    ,000 years ago). Harsh environmental conditions and characteristic lifestyle result in extremely high prevalence of several genetic diseases in Mongolians, such as alcohol dependency, obesity, Type 2 Diabetes (T2D) and lipid metabolism related diseases. As invention and wide application of new generation...... discovered the genetic structure of the ethnic group presents the features of spreading widely, high admixed and some level of population stratification. In further inferences of demographic history and gene flow events, we found different tribes present diverse population history and observed frequent gene...

  15. Highly sensitive and multiplexed platforms for allergy diagnostics

    Science.gov (United States)

    Monroe, Margo R.

    Allergy is a disorder of the immune system caused by an immune response to otherwise harmless environmental allergens. Currently 20% of the US population is allergic and 90% of pediatric patients and 60% of adult patients with asthma have allergies. These percentages have increased by 18.5% in the past decade, with predicted similar trends for the future. Here we design sensitive, multiplexed platforms to detect allergen-specific IgE using the Interferometric Reflectance Imaging Sensor (IRIS) for various clinical settings. A microarray platform for allergy diagnosis allows for testing of specific IgE sensitivity to a multitude of allergens, while requiring only small volumes of patient blood sample. However, conventional fluorescent microarray technology is limited by i) the variation of probe immobilization, which hinders the ability to make quantitative, assertive, and statistically relevant conclusions necessary in immunodiagnostics and ii) the use of fluorophore labels, which is not suitable for some clinical applications due to the tendency of fluorophores to stick to blood particulates and require daily calibration methods. This calibrated fluorescence enhancement (CaFE) method integrates the low magnification modality of IRIS with enhanced fluorescence sensing in order to directly correlate immobilized probe (major allergens) density to allergen-specific IgE in patient serum. However, this platform only operates in processed serum samples, which is not ideal for point of care testing. Thus, a high magnification modality of IRIS was adapted as an alternative allergy diagnostic platform to automatically discriminate and size single nanoparticles bound to specific IgE in unprocessed, characterized human blood and serum samples. These features make IRIS an ideal candidate for clinical and diagnostic applications, such a POC testing. The high magnification (nanoparticle counting) modality in conjunction with low magnification of IRIS in a combined instrument

  16. Indoor radon (Rn-222) concentration measurements in Cyprus using high-sensitivity portable detectors

    CERN Document Server

    Anastasiou, T; Christofides, S; Christodoulides, G

    2003-01-01

    Using high--sensitivity radon (Rn-222) portable detectors, the airborne Rn-222 concentration in the interior of various Cypriot buildings and dwellings was measured. For each preselected building and dwelling, a calibrated detector was put into a closed room, and the Rn-222 concentration was registered in sampling intervals of 2 to 4 hours for a total counting time of typically 48 hours. Rn-222 activity concentrations were found to be in the range of 6.2 to 102.8 Bq/m**3, with an overall arithmetic mean value of (19.3 +- 1.6) Bq/m**3. This value is by a factor of two below the world average (population-weighted) value of 39 Bq/m**3. The total annual effective dose equivalent to the Cypriot population was calculated to be between 0.16 and 2.6 mSv with an overall arithmetic mean value of (0.49 +- 0.04) mSv.

  17. Combined effect of noise and vibration produced by high-speed trains on annoyance in buildings.

    Science.gov (United States)

    Lee, Pyoung Jik; Griffin, Michael J

    2013-04-01

    The effects of noise and vibration on annoyance in buildings during the passage of a nearby high-speed train have been investigated in a laboratory experiment with recorded train noise and 20 Hz vibration. The noises included the effects of two types of façade: windows-open and windows-closed. Subjects were exposed to six levels of noise and six magnitudes of vibration, and asked to rate annoyance using an 11-point numerical scale. The experiment consisted of four sessions: (1) evaluation of noise annoyance in the absence of vibration, (2) evaluation of total annoyance from simultaneous noise and vibration, (3) evaluation of noise annoyance in the presence of vibration, and (4) evaluation of vibration annoyance in the absence of noise. The results show that vibration did not influence ratings of noise annoyance, but that total annoyance caused by combined noise and vibration was considerably greater than the annoyance caused by noise alone. The noise annoyance and the total annoyance caused by combined noise and vibration were associated with subject self-ratings of noise sensitivity. Two classical models of total annoyance due to combined noise sources (maximum of the single source annoyance or the integration of individual annoyance ratings) provided useful predictions of the total annoyance caused by simultaneous noise and vibration.

  18. Building high-coverage monolayers of covalently bound magnetic nanoparticles

    Science.gov (United States)

    Williams, Mackenzie G.; Teplyakov, Andrew V.

    2016-12-01

    This work presents an approach for producing a high-coverage single monolayer of magnetic nanoparticles using "click chemistry" between complementarily functionalized nanoparticles and a flat substrate. This method highlights essential aspects of the functionalization scheme for substrate surface and nanoparticles to produce exceptionally high surface coverage without sacrificing selectivity or control over the layer produced. The deposition of one single layer of magnetic particles without agglomeration, over a large area, with a nearly 100% coverage is confirmed by electron microscopy. Spectroscopic techniques, supplemented by computational predictions, are used to interrogate the chemistry of the attachment and to confirm covalent binding, rather than attachment through self-assembly or weak van der Waals bonding. Density functional theory calculations for the surface intermediate of this copper-catalyzed process provide mechanistic insight into the effects of the functionalization scheme on surface coverage. Based on this analysis, it appears that steric limitations of the intermediate structure affect nanoparticle coverage on a flat solid substrate; however, this can be overcome by designing a functionalization scheme in such a way that the copper-based intermediate is formed on the spherical nanoparticles instead. This observation can be carried over to other approaches for creating highly controlled single- or multilayered nanostructures of a wide range of materials to result in high coverage and possibly, conformal filling.

  19. Interactive Configuration of High Performance Renovation of Apartment Buildings by the use of CSP

    DEFF Research Database (Denmark)

    Vareilles, E.; Thuesen, Christian; Falcon, M.

    2013-01-01

    This paper is a prospective study which looks at the possibility of configuring high performance renovation of apartment buildings by the use of constraint satisfaction problem (CSP). This study is one part of a project called CRIBA which aims to industrialize high performance thermal renovation...... of mid-rise (up to seven stories) apartment buildings. The renovation is based on external rectangular panels, always comprising insulation and cladding, and sometimes including, in addition, doors, windows or solar modules. The panels can be fixed directly onto the walls or onto a metal structure around...... the whole building. With the new thermal envelope and equipment, the building must achieve a really low energy performance of 25 kWh=m2=year. A configuration system, based on CSP approaches, will simultaneously enable the interactive definition of the renovation, the associated bill of material (BOM...

  20. Brief Analysis on Building High Efficiency of Classroom Teaching in Primary School

    Institute of Scientific and Technical Information of China (English)

    潘智爱

    2013-01-01

    It has three aspects to discuss the strategy on how to build the high efficiency classroom teaching from the preparation before class, the teaching process and the teaching after the class. New curriculum reformation calls for the innovation of classroom to build the efficient class and then effectively inspire students’ learning enthusiasms. It requires teachers should make clear, scientific, comprehensive teaching objectives and control the whole teaching processes. Let the students enjoy the successfull learning and enhance their confidence in learning English.

  1. Shadow-based Building Detection and Segmentation in High-resolution Remote Sensing Image

    OpenAIRE

    Dongyue Chen; Shibo Shang; Chengdong Wu

    2014-01-01

    This paper proposes an effective method to extract buildings in high-resolution remote sensing images based on shadow detection. Firstly, a superpixel segmentation algorithm called SLIC is introduced to split the input image into homogeneous patches. LDA-based color features of the patches are extracted for detecting shadow regions. According to the positions of the shadows, an adaptive strategy for seed location and regional growth is developed to accomplish the coarse detection of buildings...

  2. Sunshine Group Builds High-End Aluminum Product Industrial Base

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    In order to propel development of the aluminum industry to move toward featured,specialized,and ecological directions,Sunlight Sanyuan Aluminum Company plans to expropriate 300 mu of land in Hanjiang District of Putian City,Fujian province,where it plans to construct high-end aluminum product industrial park,introduce the world’s most advanced fully automatic production equipment and technologies for aluminum profile and

  3. Building and testing a high school calorimeter at CERN

    Science.gov (United States)

    Biesot, L.; Crane, R.; Engelen, M. A. G.; van Haren, A. M. A.; van Kleef, R. H. B.; Leenders, O. R.; Timmermans, C.

    2016-11-01

    We have designed, built and tested a crystal calorimeter in the context of CERN’s first beam line for schools competition. The results of the tests at CERN show that the light output of our calorimeter depends on the energy deposited by particles (electrons and muons) hitting the crystals. Our design can be reproduced by high schools around the world, as we have avoided the use of toxic chemicals.

  4. Challenges in building high performance geoscientific spatial data infrastructures

    Science.gov (United States)

    Dubros, Fabrice; Tellez-Arenas, Agnes; Boulahya, Faiza; Quique, Robin; Le Cozanne, Goneri; Aochi, Hideo

    2016-04-01

    One of the main challenges in Geosciences is to deal with both the huge amounts of data available nowadays and the increasing need for fast and accurate analysis. On one hand, computer aided decision support systems remain a major tool for quick assessment of natural hazards and disasters. High performance computing lies at the heart of such systems by providing the required processing capabilities for large three-dimensional time-dependent datasets. On the other hand, information from Earth observation systems at different scales is routinely collected to improve the reliability of numerical models. Therefore, various efforts have been devoted to design scalable architectures dedicated to the management of these data sets (Copernicus, EarthCube, EPOS). Indeed, standard data architectures suffer from a lack of control over data movement. This situation prevents the efficient exploitation of parallel computing architectures as the cost for data movement has become dominant. In this work, we introduce a scalable architecture that relies on high performance components. We discuss several issues such as three-dimensional data management, complex scientific workflows and the integration of high performance computing infrastructures. We illustrate the use of such architectures, mainly using off-the-shelf components, in the framework of both coastal flooding assessments and earthquake early warning systems.

  5. Characterization of Three High Efficiency and Blue Sensitive Silicon Photomultipliers

    CERN Document Server

    Otte, Adam Nepomuk; Nguyen, Thanh; Purushotham, Dhruv

    2016-01-01

    We report about the optical and electrical characterization of three high efficiency and blue sensitive Silicon photomultipliers from FBK, Hamamatsu, and SensL. Key features of the tested devices when operated at 90% breakdown probability are peak photon detection efficiencies between 40% and 55%, temperature dependencies of gain and PDE that are less than 1%/$^{\\circ}$C, dark rates of $\\sim$50\\,kHz/mm$^{2}$ at room temperature, afterpulsing of about 2%, and direct optical crosstalk between 6% and 20%. The characteristics of all three devices impressively demonstrate how the Silicon-photomultiplier technology has improved over the past ten years. It is further demonstrated how the voltage and temperature characteristics of a number of quantities can be parameterized on the basis of physical models. The models provide a deeper understanding of the device characteristics over a wide bias and temperature range. They also serve as examples how producers could provide the characteristics of their SiPMs to users. A...

  6. Characterization of three high efficiency and blue sensitive silicon photomultipliers

    Science.gov (United States)

    Otte, Adam Nepomuk; Garcia, Distefano; Nguyen, Thanh; Purushotham, Dhruv

    2017-02-01

    We report about the optical and electrical characterization of three high efficiency and blue sensitive Silicon photomultipliers from FBK, Hamamatsu, and SensL. Key features of the tested devices when operated at 90% breakdown probability are peak photon detection efficiencies between 40% and 55%, temperature dependencies of gain and PDE that are less than 1%/°C, dark rates of ∼50 kHz/mm2 at room temperature, afterpulsing of about 2%, and direct optical crosstalk between 6% and 20%. The characteristics of all three devices impressively demonstrate how the Silicon-photomultiplier technology has improved over the past ten years. It is further demonstrated how the voltage and temperature characteristics of a number of quantities can be parameterized on the basis of physical models. The models provide a deeper understanding of the device characteristics over a wide bias and temperature range. They also serve as examples how producers could provide the characteristics of their SiPMs to users. A standardized parameterization of SiPMs would enable users to find the optimal SiPM for their application and the operating point of SiPMs without having to perform measurements thus significantly reducing design and development cycles.

  7. High Speed Pressure Sensitive Paint for Dynamic Testing

    Science.gov (United States)

    Pena, Carolina; Chism, Kyle; Hubner, Paul

    2016-11-01

    Pressure sensitive paint (PSP) allows engineers to obtain accurate, high-spatial-resolution measurements of pressure fields over a structure. The pressure is directly related to the luminescence emitted by the paint due to oxygen quenching. Fast PSP has a higher surface area due to its porosity compared to conventional PSP, which enables faster diffusion and measurements to be acquired three orders of magnitude faster than with conventional PSP. A fast time response is needed when testing vibrating structures due to fluid-structure interaction. The goal of this summer project was to set-up, test and analyze the pressure field of an impinging air jet on a vibrating cantilever beam using Fast PSP. Software routines were developed for the processing of the emission images, videos of a static beam coated with Fast PSP were acquired with the air jet on and off, and the intensities of these two cases were ratioed and calibrated to pressure. Going forward, unsteady pressures on a vibrating beam will be measured and presented. Eventually, the long-term goal is to integrate luminescent pressure and strain measurement techniques, simultaneously using Fast PSP and a luminescent photoelastic coating on vibrating structures. Funding from NSF REU site Grant EEC 1358991 is greatly appreciated.

  8. Ultra-high sensitivity imaging of cancer using SERRS nanoparticles

    Science.gov (United States)

    Kircher, Moritz F.

    2016-05-01

    "Surface-enhanced Raman spectroscopy" (SERS) nanoparticles have gained much attention in recent years for in silico, in vitro and in vivo sensing applications. Our group has developed novel generations of biocompatible "surfaceenhanced resonance Raman spectroscopy" (SERRS) nanoparticles as novel molecular imaging agents. Via rigorous optimization of the different variables contributing to the Raman enhancement, we were able to design SERRS nanoparticles with so far unprecedented sensitivity of detection under in vivo imaging conditions (femto-attomolar range). This has resulted in our ability to visualize, with a single nanoparticle, many different cancer types (after intravenous injection) in mouse models. The cancer types we have tested so far include brain, breast, esophagus, stomach, pancreas, colon, sarcoma, and prostate cancer. All mouse models used are state-of-the-art and closely mimic the tumor biology in their human counterparts. In these animals, we were able to visualize not only the bulk tumors, but importantly also microscopic extensions and locoregional satellite metastases, thus delineating for the first time the true extent of tumor spread. Moreover, the particles enable the detection of premalignant lesions. Given their inert composition they are expected to have a high chance for clinical translation, where we envision them to have an impact in various scenarios ranging from early detection, image-guidance in open or minimally invasive surgical procedures, to noninvasive imaging in conjunction with spatially offset (SESORS) Raman detection devices.

  9. Fabrication of highly efficient flexible dye-sensitized solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Chang, H., E-mail: f10381@ntut.edu.t [Department of Mechanical Engineering, National Taipei University of Technology, No.1 Sec.3, Chung Hsiao E. Rd., Taipei 10608, Taiwan (China); Chen, T.L. [Department of Industrial Design, National Taipei University of Technology, No.1 Sec.3, Chung Hsiao E. Rd., Taipei 10608, Taiwan (China); Huang, K.D. [Department of Vehicle Engineering, National Taipei University of Technology, No.1 Sec.3, Chung Hsiao E. Rd., Taipei 10608, Taiwan (China); Chien, S.H. [Institute of Chemistry, Academia Sinica, No. 128 Sec.2, Academia Rd., Nankang, Taipei 11529, Taiwan (China); Hung, K.C. [Department of Mechanical Engineering, National Taipei University of Technology, No.1 Sec.3, Chung Hsiao E. Rd., Taipei 10608, Taiwan (China)

    2010-08-15

    The paper studies the fabrication of a flexible dye-sensitized solar cell (DSSC). The photoelectrode substrates are flexible stainless steel sheet with thickness 0.07 mm and titanium (Ti) sheet with thickness 0.25 mm. For the photoelectrode fabrication process, eletrophoresis deposition (EPD) was employed for its merits of low-cost and fast fabrication. With an electric field of 40 V/cm, after undergoing EPD process twice, the TiO{sub 2} nanofilm thickness could be controlled to around 13 {mu}m thick. In addition, to achieve counter electrode, sputtering method was applied to deposit Pt on ITO-PET, resulting in thin films with four different thicknesses of 5, 8, 11 and 14 nm. The experimental results showed that the best colloid solution used in EPD process was a mixture of 100 ml isopropyl alcohol (IPA) and 0.4 g commercial TiO{sub 2} nanoparticles, Degussa P25. The best flatness for a 13 {mu}m thick film could be acquired under an electric field of 40 V/cm. Comparing the photoelectric conversion efficiency values of DSSC assembled by counter electrodes with different Pt thicknesses, the experimental results showed that the best Pt thickness was 11 nm, and the conversion efficiency could reach as high as 2.91%.

  10. ASIC for High Rate 3D Position Sensitive Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Vernon, E.; De Geronimo, G.; Ackley, K.; Fried, J.; He, Z.; Herman, C.; Zhang, F.

    2010-06-16

    We report on the development of an application specific integrated circuit (ASIC) for 3D position sensitive detectors (3D PSD). The ASIC is designed to operate with pixelated wide bandgap sensors like Cadmium-Zinc-Telluride (CZT), Mercuric Iodide (Hgl2) and Thallium Bromide (TIBr). It measures the amplitudes and timings associated with an ionizing event on 128 anodes, the anode grid, and the cathode. Each channel provides low-noise charge amplification, high-order shaping with peaking time adjustable from 250 ns to 12 {micro}s, gain adjustable to 20 mV/fC or 120 mV/fC (for a dynamic range of 3.2 MeV and 530 keV in CZT), amplitude discrimination with 5-bit trimming, and positive and negative peak and timing detections. The readout can be full or sparse, based on a flag and single- or multi-cycle token passing. All channels, triggered channels only, or triggered with neighbors can be read out thus increasing the rate capability of the system to more than 10 kcps. The ASIC dissipates 330 mW which corresponds to about 2.5 mW per channel.

  11. Adjoint sensitivity analysis of high frequency structures with Matlab

    CERN Document Server

    Bakr, Mohamed; Demir, Veysel

    2017-01-01

    This book covers the theory of adjoint sensitivity analysis and uses the popular FDTD (finite-difference time-domain) method to show how wideband sensitivities can be efficiently estimated for different types of materials and structures. It includes a variety of MATLAB® examples to help readers absorb the content more easily.

  12. Regionalized sensitivity analysis with respect to multiple outputs - and an application for real-time building space exploration

    DEFF Research Database (Denmark)

    Østergård, Torben

    Building design involves a large number of design parameters and performance indicators. The Monte Carlo method enables the modeler to perform thousands of building performance simulations representing a global design space. To explore such multivariate data (Factor Mapping), the parallel...

  13. A survey on classification of maintenance fund for high rise residential building in Klang Valley

    Science.gov (United States)

    Wahab, Siti Rashidah Hanum Abd; Ani, Adi Irfan Che; Sairi, Ahmad; Tawil, Norngainy Mohd; Razak, Muhd Zulhanif Abd

    2016-08-01

    High-rise residential building is a type of housing that has multi-dwelling units built on the same land. This type of housing has become popular each year in urban area due to the increasing cost of land. Unfortunately, there are several issues occurred in managing high rise residential building especially in maintenance fund. Thus, distribution of maintenance fund need to be clarified in order to make it well organised. The purpose of this paper is to identify the classification of maintenance fund distribution at high rise residential building. The survey was done on 170 high-rise residential schemes by using stratified random sampling technique. The scope of this research is within Klang Valley area. This area is rapidly developed with high-rise residential building. The result, there are five classification of maintenance fund identified in managing high-rise residential building scheme namely, management fund for administration and utilities, maintenance fund for exclusive facilities, maintenance fund for basic facilities, maintenance fund for support facilities and management sinking fund.

  14. Highly sensitive NIR PtSi/Si-nanostructure detectors

    Science.gov (United States)

    Li, Hua-gao; Guo, Pei; Yuan, An-bo; Long, Fei; Li, Rui-zhi; Li, Ping; Li, Yi

    2016-10-01

    We report a high external quantum efficiency (EQE) photodiode detector with PtSi/Si-nanostructures. Black silicon nanostructures were fabricated by metal-assist chemical etching (MCE), a 2 nm Pt layer was subsequently deposited on black silicon surface by DC magnetron sputtering system, and PtSi/Si-nanostructures were formed in vacuum annealing at 450 oC for 5 min. As the PtSi/Si-nanostructures presented a spiky shape, the absorption of incident light was remarkably enhanced for the repeat reflection and absorption. The breakdown voltage, dark current, threshold voltage and responsivity of the device were investigated to evaluate the performance of the PtSi/Si-nanostructures detector. The threshold voltage and dark currents of the PtSi/Si-nanostructure photodiode tends to be slightly higher than those of the standard diodes. The breakdown voltage remarkably was reduced because of existing avalanche breakdown in PtSi/Si-nanostructures. However, the photodiodes had high response at room temperature in near infrared region. At -5 V reverse bias voltage, the responsivity was 0.72 A/W in 1064 nm wavelength, and the EQE was 83.9%. By increasing the reverse bias voltage, the responsivity increased. At -60 V reverse bias voltage, the responsivity was 3.5 A/W, and the EQE was 407.5%, which means the quantum efficiency of PtSi/Si-nanostructure photodiodes was about 10 times higher than that of a standard diode. Future research includes how to apply this technology to enhance the NIR sensitivity of image sensors, such as Charge Coupled Devices (CCD).

  15. The Hedgehog Effect The Secrets of Building High Performance Teams

    CERN Document Server

    Kets de Vries, Manfred F R

    2011-01-01

    In The Hedgehog Effect, Manfred Kets de Vries presents the case for leadership group coaching as an experiential training ground for learning to function as a high performance team. His group coaching model, incorporating living case studies, has been developed over more than 20 years of delivering programs to top-level executives and sets the standard in the field of leadership group coaching. Written for coaches, consultants, leadership development directors, and anyone working in or with teams, The Hedgehog Effect begins with an in-depth analysis of what teams and groups are all about. The

  16. A highly sensitive electrostatic precipitator with no moving parts

    DEFF Research Database (Denmark)

    Teodosić, V.

    1968-01-01

    Cross correlation between a modulated precipitation voltage and the corresponding detector voltage variation gives a signal which is proportional to the fission gas concentration even when the precipitation electrode is not moving, which makes it possible to build a simple unit for fuel leakage d...

  17. High throughput modular chambers for rapid evaluation of anesthetic sensitivity

    Directory of Open Access Journals (Sweden)

    Eckmann David M

    2006-11-01

    Full Text Available Abstract Background Anesthetic sensitivity is determined by the interaction of multiple genes. Hence, a dissection of genetic contributors would be aided by precise and high throughput behavioral screens. Traditionally, anesthetic phenotyping has addressed only induction of anesthesia, evaluated with dose-response curves, while ignoring potentially important data on emergence from anesthesia. Methods We designed and built a controlled environment apparatus to permit rapid phenotyping of twenty-four mice simultaneously. We used the loss of righting reflex to indicate anesthetic-induced unconsciousness. After fitting the data to a sigmoidal dose-response curve with variable slope, we calculated the MACLORR (EC50, the Hill coefficient, and the 95% confidence intervals bracketing these values. Upon termination of the anesthetic, Emergence timeRR was determined and expressed as the mean ± standard error for each inhaled anesthetic. Results In agreement with several previously published reports we find that the MACLORR of halothane, isoflurane, and sevoflurane in 8–12 week old C57BL/6J mice is 0.79% (95% confidence interval = 0.78 – 0.79%, 0.91% (95% confidence interval = 0.90 – 0.93%, and 1.96% (95% confidence interval = 1.94 – 1.97%, respectively. Hill coefficients for halothane, isoflurane, and sevoflurane are 24.7 (95% confidence interval = 19.8 – 29.7%, 19.2 (95% confidence interval = 14.0 – 24.3%, and 33.1 (95% confidence interval = 27.3 – 38.8%, respectively. After roughly 2.5 MACLORR • hr exposures, mice take 16.00 ± 1.07, 6.19 ± 0.32, and 2.15 ± 0.12 minutes to emerge from halothane, isoflurane, and sevoflurane, respectively. Conclusion This system enabled assessment of inhaled anesthetic responsiveness with a higher precision than that previously reported. It is broadly adaptable for delivering an inhaled therapeutic (or toxin to a population while monitoring its vital signs, motor reflexes, and providing precise control

  18. 76 FR 65511 - Office of Governmentwide Policy; Office of Federal High-Performance Green Buildings; the Green...

    Science.gov (United States)

    2011-10-21

    ... ADMINISTRATION Office of Governmentwide Policy; Office of Federal High- Performance Green Buildings; the Green... provides the schedule and agenda for the first meeting of the Green Building Advisory Committee Meeting...: Ken Sandler, Designated Federal Official, Office of Federal High-Performance Green Buildings,...

  19. Highly insulating glazing in new multi-storey buildings; Hoejisolerende glaspartier i nye etageboliger

    Energy Technology Data Exchange (ETDEWEB)

    Engelund Thomsen, K.; Schmidt, H.; Aggerholm, S.

    2001-07-01

    The purpose of this report is to illustrate how highly insulating types of glazing can be used in multi-storey buildings for housing in new ways. These are energy efficient and provide good indoor climate and also satisfy requirements to high architectural quality. The project has resulted in a number of design proposal demonstrating how new types of glazing can be fitted into multi-storey buildings and how new facade expressions, space and lighting effects can be obtained by using highly insulating glass areas. The project is collaboration between the architects Boje Lundgaard and Lene Tranberg's Tegnestue, KAB Bygge og Boligadministration and Danish Building and Urban Research. Calculations of heat demand suggest that it is possible to meet the targets outlined in the Danish Government's action plan for energy. Energy 21 by using new types of highly insulating glazing in new buildings. Another 33% reduction of the heating demand is targeted in relation to existing requirements in the Danish Building Regulations 1995 (BR 95) and the Danish Building Regulations for Small Dwellings 1998 (BR-S 98). The project builds on experience gained from 'High-insulated Glass House' (Wittchen and Aggerholm, 1999) built on the housing estage Egebjerggaard in Ballerup, a suburb of Copenhagen. Examples of existing multi-storey buildings with glass facades show extensive use of glazing as early as 1830 in Spain. Walls preceding the curtain wall were built from wood and glass and rested on stone corbels at about 1 m from the load-bearing facade. The first multi-storey buildings with facades entirely made from glass date from the 1920s. The architect Le Corbusier was the first to create a building system that facilitated the construction of non-loadbearing facades. Various conditions must be especially considered at the design of facades with highly insulating glass areas, i.a. type of glass and glazing, solar shadings, frame constructions and airtightness

  20. High-sensitivity high-throughput chip based biosensor array for multiplexed detection of heavy metals

    Science.gov (United States)

    Yan, Hai; Tang, Naimei; Jairo, Grace A.; Chakravarty, Swapnajit; Blake, Diane A.; Chen, Ray T.

    2016-03-01

    Heavy metal ions released into the environment from industrial processes lead to various health hazards. We propose an on-chip label-free detection approach that allows high-sensitivity and high-throughput detection of heavy metals. The sensing device consists of 2-dimensional photonic crystal microcavities that are combined by multimode interferometer to form a sensor array. We experimentally demonstrate the detection of cadmium-chelate conjugate with concentration as low as 5 parts-per-billion (ppb).

  1. Distribution of background equivalent static wind load on high-rise buildings

    Institute of Scientific and Technical Information of China (English)

    Jianguo ZHANG; Ming GU

    2009-01-01

    In this paper, the along-wind and cross-wind fluctuating load distributions along the height of high-rise buildings and their correlations are obtained through simultaneous pressure measurements in a wind tunnel.Some typical methods proposed in some relative litera-tures, i.e., load-response correlation (LRC), and quasi-mean load (QML) and gust load envelope (GLE) methods,are verified in terms of their accuracy in describing the background equivalent static wind load distribution on high-rise buildings. Based on the results, formulae of the distribution of background equivalent static load on high-rise buildings with typical shapes are put forward. It is shown that these formulae are of high accuracy and practical use.

  2. Research of building information extraction and evaluation based on high-resolution remote-sensing imagery

    Science.gov (United States)

    Cao, Qiong; Gu, Lingjia; Ren, Ruizhi; Wang, Lang

    2016-09-01

    Building extraction currently is important in the application of high-resolution remote sensing imagery. At present, quite a few algorithms are available for detecting building information, however, most of them still have some obvious disadvantages, such as the ignorance of spectral information, the contradiction between extraction rate and extraction accuracy. The purpose of this research is to develop an effective method to detect building information for Chinese GF-1 data. Firstly, the image preprocessing technique is used to normalize the image and image enhancement is used to highlight the useful information in the image. Secondly, multi-spectral information is analyzed. Subsequently, an improved morphological building index (IMBI) based on remote sensing imagery is proposed to get the candidate building objects. Furthermore, in order to refine building objects and further remove false objects, the post-processing (e.g., the shape features, the vegetation index and the water index) is employed. To validate the effectiveness of the proposed algorithm, the omission errors (OE), commission errors (CE), the overall accuracy (OA) and Kappa are used at final. The proposed method can not only effectively use spectral information and other basic features, but also avoid extracting excessive interference details from high-resolution remote sensing images. Compared to the original MBI algorithm, the proposed method reduces the OE by 33.14% .At the same time, the Kappa increase by 16.09%. In experiments, IMBI achieved satisfactory results and outperformed other algorithms in terms of both accuracies and visual inspection

  3. Volatile Organic Compounds (VOCs in Conventional and High Performance School Buildings in the U.S.

    Directory of Open Access Journals (Sweden)

    Lexuan Zhong

    2017-01-01

    Full Text Available Exposure to volatile organic compounds (VOCs has been an indoor environmental quality (IEQ concern in schools and other buildings for many years. Newer designs, construction practices and building materials for “green” buildings and the use of “environmentally friendly” products have the promise of lowering chemical exposure. This study examines VOCs and IEQ parameters in 144 classrooms in 37 conventional and high performance elementary schools in the U.S. with the objectives of providing a comprehensive analysis and updating the literature. Tested schools were built or renovated in the past 15 years, and included comparable numbers of conventional, Energy Star, and Leadership in Energy and Environmental Design (LEED-certified buildings. Indoor and outdoor VOC samples were collected and analyzed by thermal desorption, gas chromatography and mass spectroscopy for 94 compounds. Aromatics, alkanes and terpenes were the major compound groups detected. Most VOCs had mean concentrations below 5 µg/m3, and most indoor/outdoor concentration ratios ranged from one to 10. For 16 VOCs, the within-school variance of concentrations exceeded that between schools and, overall, no major differences in VOC concentrations were found between conventional and high performance buildings. While VOC concentrations have declined from levels measured in earlier decades, opportunities remain to improve indoor air quality (IAQ by limiting emissions from building-related sources and by increasing ventilation rates.

  4. Volatile Organic Compounds (VOCs) in Conventional and High Performance School Buildings in the U.S.

    Science.gov (United States)

    Zhong, Lexuan; Su, Feng-Chiao; Batterman, Stuart

    2017-01-01

    Exposure to volatile organic compounds (VOCs) has been an indoor environmental quality (IEQ) concern in schools and other buildings for many years. Newer designs, construction practices and building materials for “green” buildings and the use of “environmentally friendly” products have the promise of lowering chemical exposure. This study examines VOCs and IEQ parameters in 144 classrooms in 37 conventional and high performance elementary schools in the U.S. with the objectives of providing a comprehensive analysis and updating the literature. Tested schools were built or renovated in the past 15 years, and included comparable numbers of conventional, Energy Star, and Leadership in Energy and Environmental Design (LEED)-certified buildings. Indoor and outdoor VOC samples were collected and analyzed by thermal desorption, gas chromatography and mass spectroscopy for 94 compounds. Aromatics, alkanes and terpenes were the major compound groups detected. Most VOCs had mean concentrations below 5 µg/m3, and most indoor/outdoor concentration ratios ranged from one to 10. For 16 VOCs, the within-school variance of concentrations exceeded that between schools and, overall, no major differences in VOC concentrations were found between conventional and high performance buildings. While VOC concentrations have declined from levels measured in earlier decades, opportunities remain to improve indoor air quality (IAQ) by limiting emissions from building-related sources and by increasing ventilation rates. PMID:28117727

  5. High sensitivity fiber Bragg grating pressure difference sensor

    Institute of Scientific and Technical Information of China (English)

    Haiwei Fu(傅海威); Junmei Fu(傅君眉); Xueguang Qiao(乔学光)

    2004-01-01

    Based on the effect of fiber Bragg grating (FBG) pressure difference sensitivity enhancement by encapsulating the FBG with uniform strength beam and metal bellows, a FBG pressure difference sensor is proposed, and its mechanism is also discussed. The relationship between Bragg wavelength and the pressure difference is derived, and the expression of the pressure difference sensitivity coefficient is also given. It is indicated that there is good linear relation between the Bragg wavelength shift and the pressure difference of the sensor. The theoretical and experimental pressure difference sensitivity coefficients are 38.67 and 37.6 nm/MPa, which are 12890 and 12533 times of that of the bare FBG, respectively. The pressure difference sensitivity and dynamic range can be easily changed by changing the size, Young's modulus, and Poisson's ratio of the beam and the bellows.

  6. Design of a High Sensitivity GNSS receiver for Lunar missions

    Science.gov (United States)

    Musumeci, Luciano; Dovis, Fabio; Silva, João S.; da Silva, Pedro F.; Lopes, Hugo D.

    2016-06-01

    This paper presents the design of a satellite navigation receiver architecture tailored for future Lunar exploration missions, demonstrating the feasibility of using Global Navigation Satellite Systems signals integrated with an orbital filter to achieve such a scope. It analyzes the performance of a navigation solution based on pseudorange and pseudorange rate measurements, generated through the processing of very weak signals of the Global Positioning System (GPS) L1/L5 and Galileo E1/E5 frequency bands. In critical scenarios (e.g. during manoeuvres) acceleration and attitude measurements from additional sensors complementing the GNSS measurements are integrated with the GNSS measurement to match the positioning requirement. A review of environment characteristics (dynamics, geometry and signal power) for the different phases of a reference Lunar mission is provided, focusing on the stringent requirements of the Descent, Approach and Hazard Detection and Avoidance phase. The design of High Sensitivity acquisition and tracking schemes is supported by an extensive simulation test campaign using a software receiver implementation and navigation results are validated by means of an end-to-end software simulator. Acquisition and tracking of GPS and Galileo signals of the L1/E1 and L5/E5a bands was successfully demonstrated for Carrier-to-Noise density ratios as low as 5-8 dB-Hz. The proposed navigation architecture provides acceptable performances during the considered critical phases, granting position and velocity errors below 61.4 m and 3.2 m/s, respectively, for the 99.7% of the mission time.

  7. Multi-hazard performance assessment of a transfer-plate high-rise building

    Institute of Scientific and Technical Information of China (English)

    Xiangming Zhou; Y L Xu

    2007-01-01

    Many urban areas are located in regions of moderate seismicity and are sunected to strong wind.Buildings in these regions are often designed without seismic provisions.As a result,in the event of an earthquake,the potential for damage and loss of lives may not be known.In this paper,the performance of a typical high-rise building with a thick transfer plate(TP),which is one type of building structure commonly found in Hong Kong,is assessed against both earthquake and wind hazards.Seismic-and wind-resistant performance objectives are first reviewed based on relevant codes and design guidelines for high-rise buildings.After a brief introduction of wind-resistant design of the building,various methodologies,including equivalent static load analysis (ESLA),response spectrum analysis(RSA),pushover analysis (POA),linear and nonlinear time-history analysis (LTHA and NTHA),are employed to assess the seismic performance of the building when subjected to frequent earthquakes,design based earthquakes and maximum credible earthquakes.The effects of design wind and seismic action with a common 50-year return period are also compared.The results indicate that most performance objectives can be satisfied by the building,but there are some objectives,such as inter-story drift ratio,that cannot be achieved when subjected to the frequent earthquakes.It is concluded that in addition to wind,seismic action may need to be explicitly considered in the design of buildings in regions of moderate seismicity.

  8. A high sensitive fiber-optic strain sensor with tunable temperature sensitivity for temperature-compensation measurement

    Science.gov (United States)

    Hu, Jie; Huang, Hui; Bai, Min; Zhan, Tingting; Yang, Zhibo; Yu, Yan; Qu, Bo

    2017-02-01

    A high sensitive fiber-optic strain sensor, which consists of a cantilever, a tandem rod and a fiber collimator, was proposed. The tandem rod, which transfer the applied strain to the cantilever, was used for tuning the temperature sensitivity from ‑0.15 to 0.19 dB/°C via changing the length ratio of the rods. Moreover, due to the small beam divergence of the collimator, high strain sensitivity can be realized via incident-angle sensitive detection-mechanism. A strain detection-range of 1.1 × 103 με (with a sensing length of 21.5 mm), a detection limit of 5.7 × 10‑3 με, and a maximum operating frequency of 1.18 KHz were demonstrated. This sensor is promising for compensating the thermal-expansion of various target objects.

  9. Building professional identity as computer science teachers: Supporting high school computer science teachers through reflection and community building

    Science.gov (United States)

    Ni, Lijun

    Computing education requires qualified computing teachers. The reality is that too few high schools in the U.S. have computing/computer science teachers with formal computer science (CS) training, and many schools do not have CS teacher at all. Moreover, teacher retention rate is often low. Beginning teacher attrition rate is particularly high in secondary education. Therefore, in addition to the need for preparing new CS teachers, we also need to support those teachers we have recruited and trained to become better teachers and continue to teach CS. Teacher education literature, especially teacher identity theory, suggests that a strong sense of teacher identity is a major indicator or feature of committed, qualified teachers. However, under the current educational system in the U.S., it could be challenging to establish teacher identity for high school (HS) CS teachers, e.g., due to a lack of teacher certification for CS. This thesis work centers upon understanding the sense of identity HS CS teachers hold and exploring ways of supporting their identity development through a professional development program: the Disciplinary Commons for Computing Educators (DCCE). DCCE has a major focus on promoting reflection on teaching practice and community building. With scaffolded activities such as course portfolio creation, peer review and peer observation among a group of HS CS teachers, it offers opportunities for CS teachers to explicitly reflect on and narrate their teaching, which is a central process of identity building through their participation within the community. In this thesis research, I explore the development of CS teacher identity through professional development programs. I first conducted an interview study with local HS CS teachers to understand their sense of identity and factors influencing their identity formation. I designed and enacted the professional program (DCCE) and conducted case studies with DCCE participants to understand how their

  10. Crucial problems on security assessment of a building site adjacent to an excavated high slope

    Institute of Scientific and Technical Information of China (English)

    文海家; ZHANG; Jialan; 等

    2002-01-01

    The subject of this work is the assessment on the stability of an excavated high slope in order to insure the security of the building site adjacent to the slope,which is frequently encountered in town construction in mountainous areas due to terrain limit.On the base of some typical engineering cases in Chongqing,several crucial problems on security assessment of building site adjacent to an excavated high slope,including the natural geological conditions and man-destroyed degree,engineering environment,potential failure pattern of the high slope,calculation parameters and analysis methods,are roundly discussed.It is demonstrated that the conclusion of security assessment can be determined according to the aspects above-mentioned,and the security assessment is one of the fundamental data to insure the safety of the related construction,site and buildings.

  11. Sustainable building versus ecological building

    CSIR Research Space (South Africa)

    Van Wyk, Llewellyn V

    2010-04-01

    Full Text Available and sensitivity to a site that are required to efficiently meet the energy needs of a building and occupants with renewable energy (solar, wind, geothermal, etc), designers must apply holistic design principles and take advantage of the free, naturally... Building Handbook Volume 1 Sustainable Building versus Ecological Building Llewellyn van Wyk Principal Researcher CSIR Background and Context ?Evidence is mounting that humankind, and the environment that shapes its existence, are in the midst...

  12. High spectral response heteroleptic ruthenium (II) complexes as sensitizers for dye sensitized solar cells

    Indian Academy of Sciences (India)

    M Chandrasekharam; Ch Srinivasarao; T Suresh; M Anil Reddy; M Raghavender; G Rajkumar; M Srinivasu; P Yella Reddy

    2011-01-01

    Heteroleptic ruthenium(II) bipyridyl complex, cis-Ru(II)(4,4'-bis(4-tert-butylstyryl)-2,2'-bipyridyl) (4,4'-dicarboxy-2,2'-bipyridyl) (NCS2) (H112) was synthesized and characterized by 1H-NMR, MASS, Spectrofluorometer and UV-Vis spectroscopes. The photo-voltaic performance of the sensitizer was evaluated in Dye Sensitized Solar Cell (DSSC) under irradiation of AM 1.5 G solar light and the photovoltaic characteristics were compared with those of reference cells of HRS1 and N719 fabricated under comparable conditions. Compared to N719, H112 sensitizer showed enhanced molar extinction coefficient and relatively better monochromatic incident photon-to-current conversion efficiency (IPCE) across the spectral range of 400 to 800 nm with solar energy-to-electrical conversion efficiency () of 2.43% [open circuit photovoltage (VOC) = 0.631V, short-circuit photocurrent density (JSC) = 8.96 mA/cm2, fill factor (ff) = 0.430], while values of 2.51% (VOC = 0.651V, JSC = 9.41 mA/cm2, ff = 0.410) and 2.74% (VOC = 0.705 V, JSC = 8.62 mA/cm2, ff = 0.455) were obtained for HRS1 and N719 sensitized solar cells respectively. The introduction of 4,4'-bis(4-tert-butylstyryl) moieties on one of the bipyridine moieties of N719 complex shows higher light absorption abilities, IPCE and JSC.

  13. 简析建筑电气在高层建筑中的应用%Application of Building Electric in High-rise Buildings

    Institute of Scientific and Technical Information of China (English)

    吕利强

    2014-01-01

    本文对高层建筑中如何选用建筑电气和具体施工工作进行阐述,旨在提高相关工作人员专业技术,从而完善高层建筑的电气系统。%This paper discusses how to select the building electric in high-rise building and the concrete construction method, aiming to improve the expertise of the related staff, and to perfect the electric system of high-rise building.

  14. Plausibility in Early Stages of Architectural Design: A New Tool for High-Rise Residential Buildings

    Institute of Scientific and Technical Information of China (English)

    Dirk Donath; Danny Lobos

    2009-01-01

    This paper analyzes the problem of the design of envelopes for high-rise isolated residential build-ings. The phenomenon of envelope creation appears in the early stages of the architectural design. Vari-ables that influence the final shape and size of such envelopes are then identified. This paper presents the state-of-the-art tools for the current solutions at the commercial and academic/scientific level. The variables identified in this research are the client's needs, the urban code and architectural practice, and their specific components for the final creation of a new decision support system tool based on the building information modeling (BIM) software platform, to facilitate the work in the project development and drawing production stages. This tool generates several options for building envelopes according to the parameters required by the city Zoning Planning Commission. These options then lead to deliver reliable data and a geometry that can be analyzed in a timely fashion by the engineers, builders, architects, government, and clients in the early stages of the building's design. The results show that use of specific information and communication technologies (ICT) tools in the early stages of a building design helps reduce the working time, increases confidence in the generated solution, and contributes to the exploration of altematives in a short period of time.

  15. Development of High Temperature/High Sensitivity Novel Chemical Resistive Sensor

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chonglin; Nash, Patrick; Ma, Chunrui; Enriquez, Erik; Wang, Haibing; Xu, Xing; Bao, Shangyong; Collins, Gregory

    2013-08-13

    The research has been focused to design, fabricate, and develop high temperature/high sensitivity novel multifunctional chemical sensors for the selective detection of fossil energy gases used in power and fuel systems. By systematically studying the physical properties of the LnBaCo{sub 2}O{sub 5+d} (LBCO) [Ln=Pr or La] thin-films, a new concept chemical sensor based high temperature chemical resistant change has been developed for the application for the next generation highly efficient and near zero emission power generation technologies. We also discovered that the superfast chemical dynamic behavior and an ultrafast surface exchange kinetics in the highly epitaxial LBCO thin films. Furthermore, our research indicates that hydrogen can superfast diffuse in the ordered oxygen vacancy structures in the highly epitaxial LBCO thin films, which suggest that the LBCO thin film not only can be an excellent candidate for the fabrication of high temperature ultra sensitive chemical sensors and control systems for power and fuel monitoring systems, but also can be an excellent candidate for the low temperature solid oxide fuel cell anode and cathode materials.

  16. A high-sensitivity push-pull magnetometer

    Science.gov (United States)

    Breschi, E.; Grujić, Z. D.; Knowles, P.; Weis, A.

    2014-01-01

    We describe our approach to atomic magnetometry based on the push-pull optical pumping technique. Cesium vapor is pumped and probed by a resonant laser beam whose circular polarization is modulated synchronously with the spin evolution dynamics induced by a static magnetic field. The magnetometer is operated in a phase-locked loop, and it has an intrinsic sensitivity below 20fT/√Hz , using a room temperature paraffin-coated cell. We use the magnetometer to monitor magnetic field fluctuations with a sensitivity of 300fT/√Hz .

  17. A high-sensitivity push-pull magnetometer

    CERN Document Server

    Breschi, E; Knowles, P; Weis, A

    2013-01-01

    We describe our approach to atomic magnetometry based on the push-pull optical pumping technique. Cesium vapor is pumped and probed by a resonant laser beam whose circular polarization is modulated synchronously with the spin evolution dynamics induced by a static magnetic field. The magnetometer is operated in a phase-locked loop, and it has an intrinsic sensitivity below 20fT/\\sqrt(Hz) using a room temperature paraffin-coated cell. We use the magnetometer to monitor magnetic field fluctuations with a sensitivity of 300fT/\\sqrt(Hz).

  18. High Sensitivity SPECT for Small Animals and Plants

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Gregory S. [UC Davis

    2015-02-28

    Imaging systems using single gamma-ray emitting radioisotopes typically implement collimators in order to form the images. However, a tradeoff in sensitivity is inherent in the use of collimators, and modern preclinical single-photon emission computed tomography (SPECT) systems detect a very small fraction of emitted gamma-rays (<0.3%). We have built a collimator-less system, which can reach sensitivity of 40% for 99mTc imaging, while still producing images of sufficient spatial resolution for certain applications in thin objects such as mice, small plants, and well plates used for in vitro experiments.

  19. High-speed high-sensitivity infrared spectroscopy using mid-infrared swept lasers (Conference Presentation)

    Science.gov (United States)

    Childs, David T. D.; Groom, Kristian M.; Hogg, Richard A.; Revin, Dmitry G.; Cockburn, John W.; Rehman, Ihtesham U.; Matcher, Stephen J.

    2016-03-01

    Infrared spectroscopy is a highly attractive read-out technology for compositional analysis of biomedical specimens because of its unique combination of high molecular sensitivity without the need for exogenous labels. Traditional techniques such as FTIR and Raman have suffered from comparatively low speed and sensitivity however recent innovations are challenging this situation. Direct mid-IR spectroscopy is being speeded up by innovations such as MEMS-based FTIR instruments with very high mirror speeds and supercontinuum sources producing very high sample irradiation levels. Here we explore another possible method - external cavity quantum cascade lasers (EC-QCL's) with high cavity tuning speeds (mid-IR swept lasers). Swept lasers have been heavily developed in the near-infrared where they are used for non-destructive low-coherence imaging (OCT). We adapt these concepts in two ways. Firstly by combining mid-IR quantum cascade gain chips with external cavity designs adapted from OCT we achieve spectral acquisition rates approaching 1 kHz and demonstrate potential to reach 100 kHz. Secondly we show that mid-IR swept lasers share a fundamental sensitivity advantage with near-IR OCT swept lasers. This makes them potentially able to achieve the same spectral SNR as an FTIR instrument in a time x N shorter (N being the number of spectral points) under otherwise matched conditions. This effect is demonstrated using measurements of a PDMS sample. The combination of potentially very high spectral acquisition rates, fundamental SNR advantage and the use of low-cost detector systems could make mid-IR swept lasers a powerful technology for high-throughput biomedical spectroscopy.

  20. Cavity Enhanced Optical Vernier Spectroscopy, Broad Band, High Resolution, High Sensitivity

    CERN Document Server

    Gohle, Christoph; Schliesser, Albert; Udem, Thomas; Hänsch, Theodor W

    2007-01-01

    A femtosecond frequency comb provides a vast number of equidistantly spaced narrow band laser modes that can be simultaneously tuned and frequency calibrated with 15 digits accuracy. Our Vernier spectrometer utilizes all of theses modes in a massively parallel manner to rapidly record both absorption and dispersion spectra with a sensitivity that is provided by a high finesse broad band optical resonator and a resolution that is only limited by the frequency comb line width while keeping the required setup simple.

  1. Careful modernisation of historical buildings. Wall-mounted multiple high-efficiency boiler systems; Sanierung mit Fingerspitzengefuehl. Brennwertwandgeraete als Mehrkesselanlage

    Energy Technology Data Exchange (ETDEWEB)

    Rieke, M. [Broetje (A.) Werke fuer Heizungstechnik GmbH und Co. KG, Rastede (Germany)

    2006-11-15

    The Offenburg townhall building is a historical monument of the baroque era which is still used as an office building. The technical facilities were checked and modernisation measures were planned and executed in 2005 so as to ensure high thermal comfort without interfering with the character of the building. (orig.)

  2. Overcoming barriers to high performance seismic design using lessons learned from the green building industry

    Science.gov (United States)

    Glezil, Dorothy

    NEHRP's Provisions today currently governing conventional seismic resistant design. These provisions, though they ensure the life-safety of building occupants, extensive damage and economic losses may still occur in the structures. This minimum performance can be enhanced using the Performance-Based Earthquake Engineering methodology and passive control systems like base isolation and energy dissipation systems. Even though these technologies and the PBEE methodology are effective reducing economic losses and fatalities during earthquakes, getting them implemented into seismic resistant design has been challenging. One of the many barriers to their implementation has been their upfront costs. The green building community has faced some of the same challenges that the high performance seismic design community currently faces. The goal of this thesis is to draw on the success of the green building industry to provide recommendations that may be used overcome the barriers that high performance seismic design (HPSD) is currently facing.

  3. Natural radionuclide and radiological assessment of building materials in high background radiation areas of Ramsar, Iran.

    Science.gov (United States)

    Bavarnegin, Elham; Moghaddam, Masoud Vahabi; Fathabadi, Nasrin

    2013-04-01

    Building materials, collected from different sites in Ramsar, a northern coastal city in Iran, were analyzed for their natural radionuclide contents. The measurements were carried out using a high resolution high purity Germanium (HPGe) gamma-ray spectrometer system. The activity concentration of (226)Ra, (232)Th, and (40)K content varied from below the minimum detection limit up to 86,400 Bqkg(-1), 187 Bqkg(-1), and 1350 Bqkg(-1), respectively. The radiological hazards incurred from the use of these building materials were estimated through various radiation hazard indices. The result of this survey shows that values obtained for some samples are more than the internationally accepted maximum limits and as such, the use of them as a building material pose significant radiation hazard to individuals.

  4. Pajarito Monitor: a high-sensitivity monitoring system for highly enriched uranium

    Energy Technology Data Exchange (ETDEWEB)

    Fehlau, P.E.; Coop, K.; Garcia, C. Jr.; Martinez, J.

    1984-01-01

    The Pajarito Monitor for Special Nuclear Material is a high-sensitivity gamma-ray monitoring system for detecting small quantities of highly enriched uranium transported by pedestrians or motor vehicles. The monitor consists of two components: a walk-through personnel monitor and a vehicle monitor. The personnel monitor has a plastic-scintillator detector portal, a microwave occupancy monitor, and a microprocessor control unit that measures the radiation intensity during background and monitoring periods to detect transient diversion signals. The vehicle monitor examines stationary motor vehicles while the vehicle's occupants pass through the personnel portal to exchange their badges. The vehicle monitor has four groups of large plastic scintillators that scan the vehicle from above and below. Its microprocessor control unit measures separate radiation intensities in each detector group. Vehicle occupancy is sensed by a highway traffic detection system. Each monitor's controller is responsible for detecting diversion as well as serving as a calibration and trouble-shooting aid. Diversion signals are detected by a sequential probability ratio hypothesis test that minimizes the monitoring time in the vehicle monitor and adapts itself well to variations in individual passage speed in the personnel monitor. Designed to be highly sensitive to diverted enriched uranium, the monitoring system also exhibits exceptional sensitivity for plutonium. 6 references, 9 figures, 2 tables.

  5. High Sensitive Precise 3D Accelerometer for Solar System Exploration with Unmanned Spacecrafts

    Science.gov (United States)

    Savenko, Y. V.; Demyanenko, P. O.; Zinkovskiy, Y. F.

    measuring, by analogue FOS, has been ˜ 10-4 %. Substantially accessible values are yet worse on 2-3 order. The reason of poor precise performances of measurers on the basis of analogue FOS is metrologically poor quality of a stream of optical radiation carrying out role of the carrier and receptor of the information. It is a high level of photon noise and a small blanket intensity level. First reason reflects the fact of discreteness of flow of high-energy photons, and it is consequence of second one - smallness, on absolute value, of inserted power into OF from available radiation sources (RS). Works on improvement of FO elements are carrying out. Certainly, it will be created RS allow to insert enough of power into standard OF. But simple increasing of optical flow power in measuring path of FOS will not be able to decide radically the problem of increasing of measuring prices: with raising of power in proportion of square root of its value there is raising a power of photon noises - 1000-times increase of power promises only 30-times increase of measuring precise; insertion into OF more large power (˜ 1 W for standard silicon OF) causes an appearance of non-linear effects in it, which destroying an operating principle of analogue FOS. Thus, it is needed to constatate impossibility of building, at that time, measurers of analogue FOS, concurated with traditional (electrical) measurers on measuring precise. At that all, advantages of FO, as basis of building of FO MD requires to find ways for decision of these problems. Analysis of problem of sensitivity of usual (analogue) FOS has brought us to conclusion about necessity of reviewing of principles of information signal forming in FOS and principles its next electronic processing. For radical increasing of accuracy of measurements with using FOS it is necessary to refuse analogue modulation of optical flow and to transfer to discreet its modulations, entering thus in optical flow new, non-optical, parameters, which will

  6. Advanced System Identification for High-rise Building Using Shear-Bending Model

    Directory of Open Access Journals (Sweden)

    Kohei Fujita

    2016-11-01

    Full Text Available In order to identify physical model parameters of a high-rise building, a new story stiffness identification method is presented based on a shear-bending model and the identification function. Although a shear building model may be the simplest conventional model for representing tall buildings, the system identification (SI method using that model is not necessarily appropriate. This is because the influence of bending deformation is predominant in such high-rise buildings. For this reason, a shear-bending model is used where the shear and bending stiffnesses are unknown. In the previous researches using the shear-bending model, it was difficult to identify the bending stiffnesses stably and reliably. In this paper, to overcome such instability of bending stiffness identification of the shear-bending model, a new SI algorithm using both the shear model and the shear-bending model is presented. The proposed SI algorithm is based on the observation that the fundamental-mode shape of the identified shear model is similar to that of the shear-bending model identified in the previous SI method. In order to verify the advanced SI method, two different 20-story building models are investigated in the numerical simulations. From the results of the simulations, both the shear and bending stiffnesses of the shear-bending model are identified reliably and stably in the proposed SI method.

  7. Distributed Multiple Tuned Mass Dampers for Wind Vibration Response Control of High-Rise Building

    Directory of Open Access Journals (Sweden)

    Said Elias

    2014-01-01

    Full Text Available Multiple tuned mass dampers (MTMDs distributed along height of a high-rise building are investigated for their effectiveness in vibration response control. A 76-storey benchmark building is modeled as shear type structure with a lateral degree of freedom at each floor, and tuned mass dampers (TMDs are installed at top/different floors. Suitable locations for installing the TMDs and their tuning frequencies are identified based, respectively, on the mode shapes and frequencies of the uncontrolled and controlled buildings. Multimode control strategy has been adopted, wherein each TMD is placed where the mode shape amplitude of the building is the largest or large in the particular mode being controlled and tuned with the corresponding modal frequency. Newmark’s method is used to solve the governing equations of motion for the structure. The performance of the distributed MTMDs (d-MTMDs is compared with single tuned mass damper (STMD and all the MTMDs placed at top floor. The variations of top floor acceleration and displacement under wind loads are computed to study the effectiveness of the MTMDs in vibration control of the high-rise building. It is concluded that the d-MTMDs are more effective to control wind induced vibration than the STMD and the MTMDs placed at top floor.

  8. Desensitization protocol in highly HLA-sensitized and ABO-incompatible high titer kidney transplantation.

    Science.gov (United States)

    Uchida, J; Machida, Y; Iwai, T; Naganuma, T; Kitamoto, K; Iguchi, T; Maeda, S; Kamada, Y; Kuwabara, N; Kim, T; Nakatani, T

    2010-12-01

    A positive crossmatch indicates the presence of donor-specific alloantibodies and is associated with a graft loss rate of >80%; anti-ABO blood group antibodies develop in response to exposure to foreign blood groups, resulting in immediate graft loss. However, a desensitization protocol for highly HLA-sensitized and ABO-incompatible high-titer kidney transplantation has not yet been established. We treated 6 patients with high (≥1:512) anti-A/B antibody titers and 2 highly HLA-sensitized patients. Our immunosuppression protocol was initiated 1 month before surgery and included mycophenolate mofetil (1 g/d) and/or low-dose steroid (methylprednisolone 8 mg/d). Two doses of the anti-CD20 antibody rituximab (150 mg/m(2)) were administered 2 weeks before and on the day of transplantation. We performed antibody removal with 6-12 sessions of plasmapheresis (plasma exchange or double-filtration plasmapheresis) before transplantation. Splenectomy was also performed on the day of transplantation. Postoperative immunosuppression followed the same regimen as ABO-compatible cases, in which calcineurin inhibitors were initiated 3 days before transplantation, combined with 2 doses of basiliximab. Of the 8 patients, 7 subsequently underwent successful living-donor kidney transplantation. Follow-up of our recipients showed that the patient and graft survival rates were 100%. Acute cellular rejection and antibody-mediated rejection episodes occurred in 1 of the 7 recipients. These findings suggest that our immunosuppression regimen consisting of rituximab infusions, splenectomy, plasmapheresis, and pharmacologic immunosuppression may prove to be effective as a desensitization protocol for highly HLA-sensitized and ABO-incompatible high-titer kidney transplantation. Copyright © 2010 Elsevier Inc. All rights reserved.

  9. Temperature insensitive hysteresis free highly sensitive polymer optical fiber Bragg grating humidity sensor

    DEFF Research Database (Denmark)

    Woyessa, Getinet; Nielsen, Kristian; Stefani, Alessio

    2016-01-01

    sensitivity and a high hysteresis in the humidity response, in particular when operated at high temperature. PMMA mPOFBGs annealed at high humidity show higher and more linear humidity sensitivity with negligible hysteresis. We also report how annealing at high humidity can blue-shift the FBG wavelength more...

  10. Class separation of buildings with high and low prevalence of SBS by principal component analysis

    DEFF Research Database (Denmark)

    Pommer, L.; Fick, J.; Andersson, B.

    2002-01-01

    This method was able to separate buildings with high and low prevalence of SBS in two different classes using principal component analysis (PCA). Data from the Northern Swedish Office Illness Study describing the presence and level of chemical compounds in outdoor, supply and room air, respective...

  11. A novel method to highly versatile monomeric PNA building blocks by multi component reactions

    NARCIS (Netherlands)

    Dömling, Alexander; Chi, Kai-Zu; Barrère, Mathieux

    1999-01-01

    A novel approach to monomeric PNA building blocks by a solution phase Ugi multi component reaction (MCR) is described. The reaction is easily performed in 96 well plates. The products precipitate from the reaction solution and are thus obtained in high yields and purity. Those products are not amena

  12. Highlighting High Performance Buildings: Adam Joseph Lewis Center for Environmental Studies

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-11-01

    Oberlin College's Adam Joseph Lewis Center for Environmental Studies is a high-performance building featuring an expansive photovoltaic system and a closed-loop groundwater heat pump system. Designers incorporated energy-efficient components and materials that are local, non-toxic, and durable.

  13. Methodology for estimating human perception to tremors in high-rise buildings

    Science.gov (United States)

    Du, Wenqi; Goh, Key Seng; Pan, Tso-Chien

    2016-12-01

    Human perception to tremors during earthquakes in high-rise buildings is usually associated with psychological discomfort such as fear and anxiety. This paper presents a methodology for estimating the level of perception to tremors for occupants living in high-rise buildings subjected to ground motion excitations. Unlike other approaches based on empirical or historical data, the proposed methodology performs a regression analysis using the analytical results of two generic models of 15 and 30 stories. The recorded ground motions in Singapore are collected and modified for structural response analyses. Simple predictive models are then developed to estimate the perception level to tremors based on a proposed ground motion intensity parameter—the average response spectrum intensity in the period range between 0.1 and 2.0 s. These models can be used to predict the percentage of occupants in high-rise buildings who may perceive the tremors at a given ground motion intensity. Furthermore, the models are validated with two recent tremor events reportedly felt in Singapore. It is found that the estimated results match reasonably well with the reports in the local newspapers and from the authorities. The proposed methodology is applicable to urban regions where people living in high-rise buildings might feel tremors during earthquakes.

  14. Field Monitoring of Column Shortenings in a High-Rise Building during Construction

    Directory of Open Access Journals (Sweden)

    Hyo Seon Park

    2013-10-01

    Full Text Available The automatic monitoring of shortenings of vertical members in high-rise buildings under construction is a challenging issue in the high-rise building construction field. In this study, a practical system for monitoring column shortening in a high-rise building under construction is presented. The proposed monitoring system comprises the following components: (1 a wireless sensing system and (2 the corresponding monitoring software. The wireless sensing system comprises the sensors and energy-efficient wireless sensing units (sensor nodes, master nodes, and repeater nodes, which automate the processes for measuring the strains of vertical members and transmitting the measured data to the remote server. The monitoring software enables construction administrators to monitor real-time data collected by the server via an Internet connection. The proposed monitoring system is applied to actual 66-floor and 72-floor high-rise buildings under construction. The system enables automatic and real-time measurements of the shortening of vertical members, which can result in more precise construction.

  15. Wind-tunnel investigations of pressure distribution over high-rise buildings

    CSIR Research Space (South Africa)

    Cwik, M

    2013-09-01

    Full Text Available pressure distribution over the façade of 208 m high Warsaw Trade Tower building. Wind tunnel tests were a part of a wider research project which also includes full-scale measurements and numerical simulations (CFD, FEM), in order to examine the possibility...

  16. Methodology for estimating human perception to tremors in high-rise buildings

    Science.gov (United States)

    Du, Wenqi; Goh, Key Seng; Pan, Tso-Chien

    2017-07-01

    Human perception to tremors during earthquakes in high-rise buildings is usually associated with psychological discomfort such as fear and anxiety. This paper presents a methodology for estimating the level of perception to tremors for occupants living in high-rise buildings subjected to ground motion excitations. Unlike other approaches based on empirical or historical data, the proposed methodology performs a regression analysis using the analytical results of two generic models of 15 and 30 stories. The recorded ground motions in Singapore are collected and modified for structural response analyses. Simple predictive models are then developed to estimate the perception level to tremors based on a proposed ground motion intensity parameter—the average response spectrum intensity in the period range between 0.1 and 2.0 s. These models can be used to predict the percentage of occupants in high-rise buildings who may perceive the tremors at a given ground motion intensity. Furthermore, the models are validated with two recent tremor events reportedly felt in Singapore. It is found that the estimated results match reasonably well with the reports in the local newspapers and from the authorities. The proposed methodology is applicable to urban regions where people living in high-rise buildings might feel tremors during earthquakes.

  17. A high sensitivity momentum flux measuring instrument for plasma thruster exhausts and diffusive plasmas

    Energy Technology Data Exchange (ETDEWEB)

    West, Michael D.; Charles, Christine; Boswell, Rod W. [Space Plasma, Power and Propulsion Group, Research School of Physics and Engineering, Australian National University, Canberra ACT 0200 (Australia)

    2009-05-15

    A high sensitivity momentum flux measuring instrument based on a compound pendulum has been developed for use with electric propulsion devices and radio frequency driven plasmas. A laser displacement system, which builds upon techniques used by the materials science community for surface stress measurements, is used to measure with high sensitivity the displacement of a target plate placed in a plasma thruster exhaust. The instrument has been installed inside a vacuum chamber and calibrated via two different methods and is able to measure forces in the range of 0.02-0.5 mN with a resolution of 15 {mu}N. Measurements have been made of the force produced from the cold gas flow and with a discharge ignited using argon propellant. The plasma is generated using a Helicon Double Layer Thruster prototype. The instrument target is placed about 1 mean free path for ion-neutral charge exchange collisions downstream of the thruster exit. At this position, the plasma consists of a low density ion beam (10%) and a much larger downstream component (90%). The results are in good agreement with those determined from the plasma parameters measured with diagnostic probes. Measurements at various flow rates show that variations in ion beam velocity and plasma density and the resulting momentum flux can be measured with this instrument. The instrument target is a simple, low cost device, and since the laser displacement system used is located outside the vacuum chamber, the measurement technique is free from radio frequency interference and thermal effects. It could be used to measure the thrust in the exhaust of other electric propulsion devices and the momentum flux of ion beams formed by expanding plasmas or fusion experiments.

  18. A high sensitivity momentum flux measuring instrument for plasma thruster exhausts and diffusive plasmas

    Science.gov (United States)

    West, Michael D.; Charles, Christine; Boswell, Rod W.

    2009-05-01

    A high sensitivity momentum flux measuring instrument based on a compound pendulum has been developed for use with electric propulsion devices and radio frequency driven plasmas. A laser displacement system, which builds upon techniques used by the materials science community for surface stress measurements, is used to measure with high sensitivity the displacement of a target plate placed in a plasma thruster exhaust. The instrument has been installed inside a vacuum chamber and calibrated via two different methods and is able to measure forces in the range of 0.02-0.5mN with a resolution of 15μN. Measurements have been made of the force produced from the cold gas flow and with a discharge ignited using argon propellant. The plasma is generated using a Helicon Double Layer Thruster prototype. The instrument target is placed about 1 mean free path for ion-neutral charge exchange collisions downstream of the thruster exit. At this position, the plasma consists of a low density ion beam (10%) and a much larger downstream component (90%). The results are in good agreement with those determined from the plasma parameters measured with diagnostic probes. Measurements at various flow rates show that variations in ion beam velocity and plasma density and the resulting momentum flux can be measured with this instrument. The instrument target is a simple, low cost device, and since the laser displacement system used is located outside the vacuum chamber, the measurement technique is free from radio frequency interference and thermal effects. It could be used to measure the thrust in the exhaust of other electric propulsion devices and the momentum flux of ion beams formed by expanding plasmas or fusion experiments.

  19. Highly sensitive BTX detection using surface functionalized QCM sensor

    Energy Technology Data Exchange (ETDEWEB)

    Bozkurt, Asuman Aşıkoğlu; Özdemir, Okan; Altındal, Ahmet, E-mail: altindal@yildiz.edu.tr [Department of Physics, Yildiz Technical University, Davutpasa, 34210 Istanbul (Turkey)

    2016-03-25

    A novel organic compound was designed and successfully synthesized for the fabrication of QCM based sensors to detect the low concentrations of BTX gases in indoor air. The effect of the long-range electron orbital delocalization on the BTX vapour sensing properties of azo-bridged Pcs based chemiresistor-type sensors have also been investigated in this work. The sensing behaviour of the film for the online detection of volatile organic solvent vapors was investigated by utilizing an AT-cut quartz crystal resonator. It was observed that the adsorption of the target molecules on the coating surface cause a reversible negative frequency shift of the resonator. Thus, a variety of solvent vapors can be detected by using the phthalocyanine film as sensitive coating, with sensitivity in the ppm range and response times in the order of several seconds depending on the molecular structure of the organic solvent.

  20. Highly Sensitive Cadmium Concentration Sensor Using Long Period Grating

    Directory of Open Access Journals (Sweden)

    A. S. Lalasangi

    2011-08-01

    Full Text Available In this paper we have proposed a simple and effective Long Period Grating chemical sensor for detecting the traces of Cadmium (Cd++ in drinking water at ppm level. Long Period gratings (LPG were fabricated by point-by-point technique with CO2 laser. We have characterized the LPG concentration sensor sensitivity for different solutions of Cd concentrations varying from 0.01 ppm to 0.04 ppm by injecting white Light source and observed transmitted spectra using Optical Spectrum Analyzer (OSA. Proper reagents have been used in the solutions for detection of the Cd species. The overall shift in wavelength is 10 nm when surrounding medium gradually changed from water to 0.04 ppm of cadmium concentrations. A comparative study has been done using sophisticated spectroscopic atomic absorption spectrometer (AAS and Inductively Coupled Plasma (ICP instruments. The spectral sensitivity enhancement was done by modifying grating surface with gold nanoparticles.

  1. Highly sensitive detection using Herriott cell for laser absorption spectroscopy

    Science.gov (United States)

    Zhao, Chongyi; Song, Guangming; Du, Yang; Zhao, Xiaojun; Wang, Wenju; Zhong, Liujun; Hu, Mai

    2016-11-01

    The tunable diode laser absorption spectroscopy combined with the long absorption path technique is a significant method to detect harmful gas. The long optical path could come true by Herriott cell reducing the size of the spectrometers. A 15 cm long Herriott cell with 28.8 m optical absorption path after 96 times reflection was designed that enhanced detection sensitivity of absorption spectroscopy. According to the theory data of calculation, Herriott cell is analyzed and simulated by softwares Matlab and Lighttools.

  2. HIGH SENSITIVE C-REACTIVE PROTEIN IN CEREBROVASCULAR ISCHEMIA

    OpenAIRE

    Padmalatha; Neeraja

    2016-01-01

    BACKGROUND Cerebrovascular ischemia is recognized as a major health problem, which causes significant morbidity and mortality. The main pathophysiology of ischemic stroke is atherosclerosis of cerebral vessels. Hs-CRP is a sensitive marker of inflammation tissue injury in the arterial wall, which contributes to atherosclerosis. In this study, we aim to investigate the association of hs-CRP in patients with ischemic stroke and to correlate hs-CRP levels with possible risk facto...

  3. The strain-rate sensitivity of high-strength high-toughness steels.

    Energy Technology Data Exchange (ETDEWEB)

    Dilmore, M.F. (AFRL/MNMW, Eglin AFB, FL); Crenshaw, Thomas B.; Boyce, Brad Lee

    2006-01-01

    The present study examines the strain-rate sensitivity of four high strength, high-toughness alloys at strain rates ranging from 0.0002 s-1 to 200 s-1: Aermet 100, a modified 4340, modified HP9-4-20, and a recently developed Eglin AFB steel alloy, ES-1c. A refined dynamic servohydraulic method was used to perform tensile tests over this entire range. Each of these alloys exhibit only modest strain-rate sensitivity. Specifically, the strain-rate sensitivity exponent m, is found to be in the range of 0.004-0.007 depending on the alloy. This corresponds to a {approx}10% increase in the yield strength over the 7-orders of magnitude change in strain-rate. Interestingly, while three of the alloys showed a concominant {approx}3-10% drop in their ductility with increasing strain-rate, the ES1-c alloy actually exhibited a 25% increase in ductility with increasing strain-rate. Fractography suggests the possibility that at higher strain-rates ES-1c evolves towards a more ductile dimple fracture mode associated with microvoid coalescence.

  4. Antibody desensitization therapy in highly sensitized lung transplant candidates.

    Science.gov (United States)

    Snyder, L D; Gray, A L; Reynolds, J M; Arepally, G M; Bedoya, A; Hartwig, M G; Davis, R D; Lopes, K E; Wegner, W E; Chen, D F; Palmer, S M

    2014-04-01

    As HLAs antibody detection technology has evolved, there is now detailed HLA antibody information available on prospective transplant recipients. Determining single antigen antibody specificity allows for a calculated panel reactive antibodies (cPRA) value, providing an estimate of the effective donor pool. For broadly sensitized lung transplant candidates (cPRA ≥ 80%), our center adopted a pretransplant multi-modal desensitization protocol in an effort to decrease the cPRA and expand the donor pool. This desensitization protocol included plasmapheresis, solumedrol, bortezomib and rituximab given in combination over 19 days followed by intravenous immunoglobulin. Eight of 18 candidates completed therapy with the primary reasons for early discontinuation being transplant (by avoiding unacceptable antigens) or thrombocytopenia. In a mixed-model analysis, there were no significant changes in PRA or cPRA changes over time with the protocol. A sub-analysis of the median fluorescence intensity (MFI) change indicated a small decline that was significant in antibodies with MFI 5000-10,000. Nine of 18 candidates subsequently had a transplant. Posttransplant survival in these nine recipients was comparable to other pretransplant-sensitized recipients who did not receive therapy. In summary, an aggressive multi-modal desensitization protocol does not significantly reduce pretransplant HLA antibodies in a broadly sensitized lung transplant candidate cohort. © Copyright 2014 The American Society of Transplantation and the American Society of Transplant Surgeons.

  5. Modeling Methodology of Progressive Collapse by the Example of Real High-Rise Buildings

    Directory of Open Access Journals (Sweden)

    Mariya Barabash

    2014-12-01

    Full Text Available The purpose of the research was to find out several ways to design real buildings with protective measures against progressive collapse. There are no uniform guidelines for choosing the type of finite element able to provide the necessary accuracy of the calculation model taking into account all the main factors affecting the strength and stability of the building. Therefore it is required to develop numerical methods for calculation on progressive collapse of buildings bearing structural elements in case of emergency. In addition, our task was to present a methodology that allows checking the stability of the building agains progressive collapse. By the technique nonlinear analysis on special (emergency regulations combination of loads and impacts is performed, including permanent and long-term regulatory burden and the impact of hypothetical local fractures bearing structures. This study was carried out on the high rise apartment complex with underground parking. In the empirical part of the study the main concern was to find out the reasons of progressive collapse of structures, taking into account stepwise assembly, building inspection performed rollover. Also the existing building retail and office complex “Gulliver” with public facilities and parking is considered, where computation was made on the progressive collapse of the upper slab technical floor. The calculation was carried out on plates or emergency landing helicopter crash on the floor slab. Analysis of the results leads to the following conclusions. To assess the real vitality of the building in an emergency situation, and resistance to progressive collapse it is recommended to count design taking into account physical and geometric nonlinearity and process modeling lifecycle.

  6. The Airborne Transmission of Infection Between Flats in High-rise Residential Buildings

    DEFF Research Database (Denmark)

    Gao, N.P.; Niu, J. L.; Perino, M.;

    2008-01-01

    in high-rise residential buildings, one of which is the natural ventilative airflow through open windows between flats, caused by buoyancy effects. Our early on-site measurement using tracer gases confirmed qualitatively and quantitatively that the re-entry of the exhaust-polluted air from the window...... of magnitude, but the risk of infection calculated by the Wells-Riley equation is only around one order of magnitude lower. It is found that, with single-side open-window conditions, wind blowing perpendicularly to the building may either reinforce or suppress the upward transport, depending on the wind speed...

  7. Nearly zero energy buildings and proliferation of microorganisms a current issue for highly insulated and airtight building envelopes

    CERN Document Server

    Di Giuseppe, Elisa

    2013-01-01

    This book provides a concise review of the thermo-physical phenomena which regulate heat and moisture transportation in Nearly Zero Energy Buildings envelopes, and their relationship with the growth of biological organisms. It describes the main microorganisms proliferating on contemporary building elements and within buildings. It also states the consequences of biological growth on durability, aesthetics and human health; and provides the main methods for the analytical and experimental evaluation of proliferation. Finally, through the review of recent developments, remedial actions to count

  8. High-rise buildings under multi-hazard environment assessment and design for optimal performance

    CERN Document Server

    Huang, Mingfeng

    2017-01-01

    This book discusses performance-based seismic and wind-resistant design for high-rise building structures, with a particular focus on establishing an integrated approach for performance-based wind engineering, which is currently less advanced than seismic engineering. This book also provides a state-of-the-art review of numerous methodologies, including computational fluid dynamics (CFD), extreme value analysis, structural optimization, vibration control, pushover analysis, response spectrum analysis, modal parameter identification for the assessment of the wind-resistant and seismic performance of tall buildings in the design stage and actual tall buildings in use. Several new structural optimization methods, including the augmented optimality criteria method, have been developed and employed in the context of performance-based design. This book is a valuable resource for students, researchers and engineers in the field of civil and structural engineering.

  9. Impacts of orientation on daylighting in high-rise office buildings in Malaysia

    Directory of Open Access Journals (Sweden)

    AbdolHamid Mahdavi

    2015-12-01

    Full Text Available Orientation is one of the important factors in building design to use daylight and ‎conserve energy. Well-orientated buildings maximise daylight reception through ‎building facades and reduce the need for artificial lighting. Reasonable daylighting usage in office buildings is an important part of an architect’s designing process, which leads to lesser electricity consumption as well as providing a visual and thermal comfort for the occupants. Orientation is an important factor in passive design strategies. This paper focuses on the orientation effect on daylighting into office rooms. The research method of this study was simulation which is performed on a hypothetical model on a 25 storey high-rise office building in Malaysia. All simulations were carried out in the IES-VE software that uses RADIANCE program for illuminance calculations. To evaluate the daylight in various conditions, a new index SAZ was introduced which assesses daylight factor (DF and absolute Lux. Results showed similar SAZ in CIE overcast sky in various orientations; whereas, in sunny sky due to sun path in Malaysia, different results showed northern and southern rooms have the best illuminance distribution. However, the similar window form and size in four orientations lead to more energy consumption for artificial lighting and cooling loads.

  10. Highly sensitive method for diagnosis of subclinical B. ovis infection.

    Science.gov (United States)

    Horta, Sara; Barreto, Maria C; Pepe, Ana; Campos, Joana; Oliva, Abel

    2014-10-01

    Babesia ovis is a tick-transmitted protozoa parasite that infects small ruminants causing fever, anaemia, hemoglobinuria, anorexia and, in acute cases, death. Common in tropical and sub-tropical areas, the presence of this parasite in sheep herds has an economic impact on industry and therefore sensitive methods for the diagnosis and disease eradication are required. To achieve this goal, a semi-nested PCR for B. ovis specific identification was developed and consequent reaction conditions and enzymes were optimized and tested with field samples. 300 blood samples from small ruminants and 39 ticks from Rhipicephalus genus were collected from different regions of Portugal. Afterwards, DNA extraction was performed and conventional and semi-nested PCR were accomplished for all samples. The results obtained from both methodologies were compared and the sensitivity was evaluated. Employing the semi-nested PCR it was possible to identify a higher number of positive cases among the evaluated samples than using the conventional PCR, namely 38/300 blood samples and 7/39 ticks. However, fragment amplification was only observed in 5 out of 300 blood samples and in none of the 39 ticks when a conventional PCR was employed. The validation of the results was achieved by sequencing the DNA fragments corresponding to the hypervariable v4 region of the 18S ribosomal RNA gene and performing an alignment with sequences already published on GenBank(®). The ticks collected in this study belong to the Rhipicephalus genus, although other species could be involved as a vector in the Babesia spread. The diagnostic assay here described is presently the most effective and sensitive method for detection of B. ovis in field blood samples and ticks, enabling the detection up to 1 parasite into 10(9) erythrocytes. Copyright © 2014 Elsevier GmbH. All rights reserved.

  11. HIGHLY SENSITIVE TIMER-BASED RESISTANCE DEVIATION TO TIME CONVERTER

    Directory of Open Access Journals (Sweden)

    Sheroz Khan

    2012-02-01

    Full Text Available Based on an inexpensive popular precision timing chip 555 timer, a resistance to time converter is proposed in this paper which is indeed capable of converting resistive and capacitive changes into pulse widths of proportional durations. This converter exhibits a compatibility of wider conversion range with a reasonable level of sensitivity required for industrial applications. The circuit is expected to have utility in oil and water supply schemes. Simulated results are shown to be compared with mathematical derivations, both reporting a good level of resemblance and similarities.

  12. High order sensitivity analysis of complex, coupled systems

    Science.gov (United States)

    Sobieszczanski-Sobieski, Jaroslaw

    1990-01-01

    The Sobieszczanski-Sobieski (1988) algorithm is extended to include second- and higher-order derivatives while retaining the obviation of finite-differencing of the system analysis. This is accomplished by means of a recursive application of the same implicit function theorem as in the original algorithm. In optimization, the computational cost of the higher-order derivatives is relative to the aggregate cost of analysis together with a repetition of the first-order sensitivity analysis as often as is required to produce the equivalent information by successive linearizations within move limits.

  13. Analysis of Cyberbullying Sensitivity Levels of High School Students and Their Perceived Social Support Levels

    Science.gov (United States)

    Akturk, Ahmet Oguz

    2015-01-01

    Purpose: The purpose of this paper is to determine the cyberbullying sensitivity levels of high school students and their perceived social supports levels, and analyze the variables that predict cyberbullying sensitivity. In addition, whether cyberbullying sensitivity levels and social support levels differed according to gender was also…

  14. Analysis of Cyberbullying Sensitivity Levels of High School Students and Their Perceived Social Support Levels

    Science.gov (United States)

    Akturk, Ahmet Oguz

    2015-01-01

    Purpose: The purpose of this paper is to determine the cyberbullying sensitivity levels of high school students and their perceived social supports levels, and analyze the variables that predict cyberbullying sensitivity. In addition, whether cyberbullying sensitivity levels and social support levels differed according to gender was also…

  15. Sensitivity analysis for high accuracy proximity effect correction

    Science.gov (United States)

    Thrun, Xaver; Browning, Clyde; Choi, Kang-Hoon; Figueiro, Thiago; Hohle, Christoph; Saib, Mohamed; Schiavone, Patrick; Bartha, Johann W.

    2015-10-01

    A sensitivity analysis (SA) algorithm was developed and tested to comprehend the influences of different test pattern sets on the calibration of a point spread function (PSF) model with complementary approaches. Variance-based SA is the method of choice. It allows attributing the variance of the output of a model to the sum of variance of each input of the model and their correlated factors.1 The objective of this development is increasing the accuracy of the resolved PSF model in the complementary technique through the optimization of test pattern sets. Inscale® from Aselta Nanographics is used to prepare the various pattern sets and to check the consequences of development. Fraunhofer IPMS-CNT exposed the prepared data and observed those to visualize the link of sensitivities between the PSF parameters and the test pattern. First, the SA can assess the influence of test pattern sets for the determination of PSF parameters, such as which PSF parameter is affected on the employments of certain pattern. Secondly, throughout the evaluation, the SA enhances the precision of PSF through the optimization of test patterns. Finally, the developed algorithm is able to appraise what ranges of proximity effect correction is crucial on which portion of a real application pattern in the electron beam exposure.

  16. Development of a high sensitive MEMS hydrophone using PVDF

    Science.gov (United States)

    Varadan, Vijay K.; Zhu, Bei; K. A, Jose

    2002-05-01

    The design and experimental evaluation of a PVDF-based MEMS hydrophone is presented in this paper. The basic structure of the hydrophone was fabricated on a silicon wafer using standard NMOS process technology. A MOSFET with extended gate electrode was designed as the interface circuit to the sensing material, which is a piezoelectric polymer, polyvinylidene difluoride (PVDF). Acoustic impedance possessed by this piezoelectric material provides a reasonable match to water, which makes it very attractive for underwater applications. The electrical signal generated by the PVDF film was directly coupled to the gate of the MOSFET. To minimize the parasitic capacitance underneath the PVDF film and hence improve the device sensitivity, a thick photoresist was first employed as the dielectric layer under the extended gate electrode. For underwater operation, a waterproof Rho-C rubber encapsulated the hydrophone. A silicon nitride layer passivated the active device, which is a good barrier material to most mobile ions and solvents. The device after passivation also shows a lower noise level. The theoretical model developed to predict the sensitivity of the hydrophone shows a reasonable agreement between the theory and the experiment.

  17. Photothermal Microscopy for High Sensitivity and High Resolution Absorption Contrast Imaging of Biological Tissues

    Directory of Open Access Journals (Sweden)

    Jun Miyazaki

    2017-04-01

    Full Text Available Photothermal microscopy is useful to visualize the distribution of non-fluorescence chromoproteins in biological specimens. Here, we developed a high sensitivity and high resolution photothermal microscopy with low-cost and compact laser diodes as light sources. A new detection scheme for improving signal to noise ratio more than 4-fold is presented. It is demonstrated that spatial resolution in photothermal microscopy is up to nearly twice as high as that in the conventional widefield microscopy. Furthermore, we demonstrated the ability for distinguishing or identifying biological molecules with simultaneous muti-wavelength imaging. Simultaneous photothermal and fluorescence imaging of mouse brain tissue was conducted to visualize both neurons expressing yellow fluorescent protein and endogenous non-fluorescent chromophores.

  18. High temperature probe sensor with high sensitivity based on Michelson interferometer

    Science.gov (United States)

    Zhao, Na; Fu, Haiwei; Shao, Min; Yan, Xu; Li, Huidong; Liu, Qinpeng; Gao, Hong; Liu, Yinggang; Qiao, Xueguang

    2015-05-01

    A novel Michelson interferometer based on a bi-taper is achieved. Such a device is fabricated by splicing a section of thin core fiber (TCF) at one end of single-mode fiber (SMF). Due to the fiber bi-taper at the splicing point of SMF and TCF, the light is coupled into the fiber core and cladding from lead in fiber core. The light will be reflected at the end of the fiber and then will be recoupled back into the lead out fiber core by the fiber bi-taper. While the light returns back to the lead out fiber, the intermodal interference will occur for the optical path difference between core mode and cladding mode. A high temperature sensitivity of 0.140 nm/°C is achieved from 30 to 800 °C, and the linearity is 99.9%. The configuration features the advantages of easy fabrication, a compact size, high sensitivity, wide sensing range and high mechanical strength, making it a good candidate for distant temperature sensing and oil prospecting.

  19. Double Wall Framing Technique An Example of High Performance, Sustainable Building Envelope Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kosny, Dr. Jan [Fraunhofer Center for Sustainable Energy Systems (CSE), Boston; Asiz, Andi [Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia; Shrestha, Som S [ORNL; Biswas, Kaushik [ORNL; Nitin, Shukla [Fraunhofer Center for Sustainable Energy Systems (CSE), Boston

    2015-01-01

    Double wall technologies utilizing wood framing have been well-known and used in North American buildings for decades. Most of double wall designs use only natural materials such as wood products, gypsum, and cellulose fiber insulation, being one of few building envelope technologies achieving high thermal performance without use of plastic foams or fiberglass. Today, after several material and structural design modifications, these technologies are considered as highly thermally efficient, sustainable option for new constructions and sometimes, for retrofit projects. Following earlier analysis performed for U.S. Department of Energy by Fraunhofer CSE, this paper discusses different ways to build double walls and to optimize their thermal performance to minimize the space conditioning energy consumption. Description of structural configuration alternatives and thermal performance analysis are presented as well. Laboratory tests to evaluate thermal properties of used insulation and whole wall system thermal performance are also discussed in this paper. Finally, the thermal loads generated in field conditions by double walls are discussed utilizing results from a joined project performed by Zero Energy Building Research Alliance and Oak Ridge National Laboratory (ORNL), which made possible evaluation of the market viability of low-energy homes built in the Tennessee Valley. Experimental data recorded in two of the test houses built during this field study is presented in this work.

  20. Building America

    Energy Technology Data Exchange (ETDEWEB)

    Brad Oberg

    2010-12-31

    IBACOS researched the constructability and viability issues of using high performance windows as one component of a larger approach to building houses that achieve the Building America 70% energy savings target.

  1. Ultrathin Two-Dimensional Covalent Organic Framework Nanosheets: Preparation and Application in Highly Sensitive and Selective DNA Detection

    KAUST Repository

    Peng, Yongwu

    2017-06-03

    The ability to prepare ultrathin two-dimensional (2D) covalent organic framework (COF) nanosheets (NSs) in high yield is of great importance for the further exploration of their unique properties and potential applications. Herein, by elaborately designing and choosing two flexible molecules with C3v molecular symmetry as building units, a novel imine-linked COF, namely TPA-COF, with hexagonal layered structure and sheet-like morphology, is synthesized. Since the flexible building units are integrated into the COF skeletons, the interlayer stacking becomes weak, resulting in the easy exfoliation of TPA-COF into ultrathin 2D NSs. Impressively, for the first time, the detailed structural information, i.e. the pore channels and individual building units in the NSs, is clearly visualized by using the recently developed low-dose imaging technique of transmission electron microscopy (TEM). As a proof-of-concept application, the obtained ultrathin COF NSs are used as a novel fluorescence sensing platform for the highly sensitive and selective detection of DNA.

  2. Highly sensitive methods for electroanalytical chemistry based on nanotubule membranes.

    Science.gov (United States)

    Kobayashi, Y; Martin, C R

    1999-09-01

    Two new methods of electroanalysis are described. These methods are based on membranes containing monodisperse Au nanotubules with inside diameters approaching molecular dimensions. In one method, the analyte species is detected by measuring the change in trans-membrane current when the analyte is added to the nanotubule-based cell. The second method entails the use of a concentration cell based on the nanotubule membrane. In this case, the change in membrane potential is used to detect the analyte. Detection limits as low as 10(-11) M have been achieved. Hence, these methods compete with even the most sensitive of modern analytical methodologies. In addition, excellent molecular-sized-based selectivity is observed.

  3. A new compact, high sensitivity neutron imaging system

    Energy Technology Data Exchange (ETDEWEB)

    Caillaud, T.; Landoas, O.; Briat, M.; Rosse, B.; Thfoin, I.; Philippe, F.; Casner, A.; Bourgade, J. L.; Disdier, L. [CEA, DAM, DIF,F-91297 Arpajon (France); Glebov, V. Yu.; Marshall, F. J.; Sangster, T. C. [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623-1299 (United States); Park, H. S.; Robey, H. F.; Amendt, P. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

    2012-10-15

    We have developed a new small neutron imaging system (SNIS) diagnostic for the OMEGA laser facility. The SNIS uses a penumbral coded aperture and has been designed to record images from low yield (10{sup 9}-10{sup 10} neutrons) implosions such as those using deuterium as the fuel. This camera was tested at OMEGA in 2009 on a rugby hohlraum energetics experiment where it recorded an image at a yield of 1.4 Multiplication-Sign 10{sup 10}. The resolution of this image was 54 {mu}m and the camera was located only 4 meters from target chamber centre. We recently improved the instrument by adding a cooled CCD camera. The sensitivity of the new camera has been fully characterized using a linear accelerator and a {sup 60}Co {gamma}-ray source. The calibration showed that the signal-to-noise ratio could be improved by using raw binning detection.

  4. Carbon nanotube quantum dots as highly sensitive THz spectrometers

    Science.gov (United States)

    Rinzan, Mohamed; Jenkins, Greg; Drew, Dennis; Shafranjuk, Serhii; Barbara, Paola

    2012-02-01

    We show that carbon nanotube quantum dots (CNT-Dots) coupled to antennas are extremely sensitive, broad-band, terahertz quantum detectors. Their response is due to photon-assisted single-electron tunneling (PASET)[1], but cannot be fully understood with orthodox PASET models[2]. We consider intra-dot excitations and non-equilibrium cooling to explain the anomalous response. REFERENCES: [1] Y. Kawano, S. Toyokawa, T. Uchida and K. Ishibashi, THz photon assisted tunneling in carbon-nanotube quantum dots, Journal of Applied Physics 103, 034307 (2008). [2] P. K. Tien and J. P. Gordon, Multiphoton Process Observed in the Interaction of Microwave Fields with the Tunneling between Superconductor Films, Phys. Rev. 129, 647 (1963).

  5. High-sensitivity observations of solar flare decimeter radiation

    CERN Document Server

    Benz, Arnold O; Monstein, C; Benz, Arnold O.; Messmer, Peter; Monstein, Christian

    2000-01-01

    A new acousto-optic radio spectrometer has observed the 1 - 2 GHz radio emission of solar flares with unprecedented sensitivity. The number of detected decimeter type III bursts is greatly enhanced compared to observations by conventional spectrometers observing only one frequency at the time. The observations indicate a large number of electron beams propagating in dense plasmas. For the first time, we report weak, reversed drifting type III bursts at frequencies above simultaneous narrowband decimeter spikes. The type III bursts are reliable signatures of electron beams propagating downward in the corona, apparently away from the source of the spikes. The observations contradict the most popular spike model that places the spike sources at the footpoints of loops. Conspicuous also was an apparent bidirectional type U burst forming a fish-like pattern. It occurs simultaneously with an intense U-burst at 600-370 MHz observed in Tremsdorf. We suggest that it intermodulated with strong terrestrial interference ...

  6. Highly sensitive biosensors based on water-soluble conjugated polymers

    Institute of Scientific and Technical Information of China (English)

    XU Hui; WU Haiping; FAN Chunhai; LI Wenxin; ZHANG Zhizhou; HE Lin

    2004-01-01

    Conjugated, conductive polymers are a kind of important organic macromolecules, which has found applications in a variety of areas. The application of conjugated polymers in developing fluorescent biosensors represents the merge of polymer sciences and biological sciences. Conjugated polymers are very good light harvesters as well as fluorescent polymers, and they are also "molecular wires". Through elaborate designs, these important features, i.e. efficient light harvesting and electron/energy transfer, can be used as signal amplification in fluorescent biosensors. This might significantly improve the sensitivity of conjugated polymer-based biosensors. In this article, we reviewed the application of conjugated polymers, via either electron transfer or energy transfer, to detections of gene targets, antibodies or enzymes. We also reviewed recent efforts in conjugated polymer-based solid-state sensor designs as well as chip-based multiple target detection. Possible directions in this conjugated polymer-based biosensor area are also discussed.

  7. Highly sensitive urea sensing with ion-irradiated polymer foils

    Energy Technology Data Exchange (ETDEWEB)

    Fink, Dietmar, E-mail: fink@daad-alumni.de [Departamento de Fisica, Universidad Autonoma Metropolitana-Iztapalapa, P.O. Box 55-534, 09340 Mexico, D.F. (Mexico); Nuclear Physics Institute, Academy of Sciences of the Czech Republic, 250 68 Rez (Czech Republic); Munoz Hernandez, Gerardo [Departamento de Fisica, Universidad Autonoma Metropolitana-Iztapalapa, P.O. Box 55-534, 09340 Mexico, D.F. (Mexico); Division de Ciencias Naturales e Ingenieria, Universidad Autonoma Metropolitana-Cuajimalpa, Pedro Antonio de los Santos 84, Col. Sn. Miguel Chapultepec, C.P. 11850, Mexico, D.F. (Mexico); Alfonta, Lital, E-mail: alfontal@bgu.ac.il [Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105 (Israel)

    2012-02-15

    Recently we prepared urea-sensors by attaching urease to the inner walls of etched ion tracks within thin polymer foil. Here, alternative track-based sensor configurations are examined where the enzyme remained in solution. The conductivities of systems consisting of two parallel irradiated polymer foils and confining different urea/urease mixtures in between were examined. The correlations between conductivity and urea concentration differed strongly for foils with unetched and etched tracks, which points at different sensing mechanisms - tentatively attributed to the adsorption of enzymatic reaction products on the latent track entrances and to the enhanced conductivity of reaction product-filled etched tracks, respectively. All examined systems enable in principle, urea sensing. They point at the possibility of sensor cascade construction for more sensitive or selective sensor systems.

  8. Introduction to Cost Control Strategies for Zero Energy Buildings: High-Performance Design and Construction on a Budget (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-09-01

    Momentum behind zero energy building design and construction is increasing, presenting a tremendous opportunity for advancing energy performance in the commercial building industry. At the same time, there is a lingering perception that zero energy buildings must be cost prohibitive or limited to showcase projects. Fortunately, an increasing number of projects are demonstrating that high performance can be achieved within typical budgets. This factsheet highlights replicable, recommended strategies for achieving high performance on a budget, based on experiences from past projects.

  9. Developing a next-generation community college curriculum forenergy-efficient high-performance building operations

    Energy Technology Data Exchange (ETDEWEB)

    Crabtree, Peter; Kyriakopedi, Nick; Mills, Evan; Haves, Philip; Otto, Roland J.; Piette, Mary Ann; Xu, Peng; Diamond, Rick; Frost, Chuck; Deringer, Joe

    2004-05-01

    The challenges of increased technological demands in today's workplace require virtually all workers to develop higher-order cognitive skills including problem solving and systems thinking in order to be productive. Such ''habits of mind'' are viewed as particularly critical for success in the information-based workplace, which values reduced hierarchy, greater worker independence, teamwork, communications skills, non-routine problem solving, and understanding of complex systems. The need is particularly compelling in the buildings arena. To scope the problem, this paper presents the results of interviews and focus groups--conducted by Oakland California's Peralta Community College District and Lawrence Berkeley National Laboratory--in which approximately 50 industry stakeholders discussed contemporary needs for building operator education at the community college level. Numerous gaps were identified between the education today received by building operators and technicians and current workplace needs. The participants concurred that many of the problems seen today in achieving and maintaining energy savings in buildings can be traced to inadequacies in building operation and lack of awareness and knowledge about how existing systems are to be used, monitored, and maintained. Participants and others we interviewed affirmed that while these issues are addressed in various graduate-level and continuing education programs, they are virtually absent at the community college level. Based on that assessment of industry needs, we present a new curriculum and innovative simulation-based learning tool to provide technicians with skills necessary to commission and operate high-performance buildings, with particular emphasis on energy efficiency and indoor environmental quality in the context of HVAC&R equipment and control systems.

  10. Automatic Building Detection based on Supervised Classification using High Resolution Google Earth Images

    Science.gov (United States)

    Ghaffarian, S.; Ghaffarian, S.

    2014-08-01

    This paper presents a novel approach to detect the buildings by automization of the training area collecting stage for supervised classification. The method based on the fact that a 3d building structure should cast a shadow under suitable imaging conditions. Therefore, the methodology begins with the detection and masking out the shadow areas using luminance component of the LAB color space, which indicates the lightness of the image, and a novel double thresholding technique. Further, the training areas for supervised classification are selected by automatically determining a buffer zone on each building whose shadow is detected by using the shadow shape and the sun illumination direction. Thereafter, by calculating the statistic values of each buffer zone which is collected from the building areas the Improved Parallelepiped Supervised Classification is executed to detect the buildings. Standard deviation thresholding applied to the Parallelepiped classification method to improve its accuracy. Finally, simple morphological operations conducted for releasing the noises and increasing the accuracy of the results. The experiments were performed on set of high resolution Google Earth images. The performance of the proposed approach was assessed by comparing the results of the proposed approach with the reference data by using well-known quality measurements (Precision, Recall and F1-score) to evaluate the pixel-based and object-based performances of the proposed approach. Evaluation of the results illustrates that buildings detected from dense and suburban districts with divers characteristics and color combinations using our proposed method have 88.4 % and 853 % overall pixel-based and object-based precision performances, respectively.

  11. CALCULATION OF THE UNIQUE HIGH-RISE BUILDING FOR EARTHQUAKES IN NONLINEAR DYNAMIC FORMULATION

    Directory of Open Access Journals (Sweden)

    Mkrtychev Oleg Vartanovich

    2016-06-01

    Full Text Available The article contains the calculation of a 80-storey high-rise building on 3-component accelerograms with different dominant frequencies. The “Akhmat Tower” belongs to the complex “Grozny-city 2” and is classified as a unique construction, its height is 400 m. During the construction unique high-rise buildings and high-rise buildings in seismic areas an additional computational studies are required, which should take into account the nonlinear nature of the design. For the case of linear instrumental-synthesized accelerograms, it is necessary to apply nonlinear dynamic methods. The studies were conducted using the software LS-DYNA, implementing the methods of direct integration of the equations of motion by the explicit scheme. The constructive scheme of the building frame is braced, the spatial stability is ensured by load-bearing interior walls, columns and hard disks, and frame metal coatings. The choice of the type and dimensions of the finite element and the step of integration is due to the ability to perform calculations in reasonable time, and to the required accuracy of calculation. For this aim the issues of convergence of the solutions on a number of settlement schemes were investigated with the terms of thickened mesh of finite elements: 0.5 m; 1 m; 2 m; 3 m. As a result of the research it was obtained that the best is to split into finite elements with a characteristic size of 2 m. The calculation of the building is made on rigid foundation. The authors used accelerograms normalized for earthquakes of 8 and 9 points on the MSK-64 scale. The destruction of the elements in the process of loading, and the interaction of the elements during their contact was taken into account, i.e. the calculation was made taking into account physical, geometrical and structural nonlinearities. The article analyzes the results of the calculation. The authors evaluated the seismic stability of the building. Possible ways to improve the seismic

  12. High-sensitivity in situ QCLAS-based ammonia concentration sensor for high-temperature applications

    Science.gov (United States)

    Peng, W. Y.; Sur, R.; Strand, C. L.; Spearrin, R. M.; Jeffries, J. B.; Hanson, R. K.

    2016-07-01

    A novel quantum cascade laser (QCL) absorption sensor is presented for high-sensitivity in situ measurements of ammonia (hbox {NH}_3) in high-temperature environments, using scanned wavelength modulation spectroscopy (WMS) with first-harmonic-normalized second-harmonic detection (scanned WMS-2 f/1 f) to neutralize the effect of non-absorption losses in the harsh environment. The sensor utilized the sQ(9,9) transition of the fundamental symmetric stretch band of hbox {NH}_3 at 10.39 {\\upmu }hbox {m} and was sinusoidally modulated at 10 kHz and scanned across the peak of the absorption feature at 50 Hz, leading to a detection bandwidth of 100 Hz. A novel technique was used to select an optimal WMS modulation depth parameter that reduced the sensor's sensitivity to spectral interference from hbox {H}_2hbox {O} and hbox {CO}_2 without significantly sacrificing signal-to-noise ratio. The sensor performance was validated by measuring known concentrations of hbox {NH}_3 in a flowing gas cell. The sensor was then demonstrated in a laboratory-scale methane-air burner seeded with hbox {NH}_3, achieving a demonstrated detection limit of 2.8 ± 0.26 ppm hbox {NH}_3 by mole at a path length of 179 cm, equivalence ratio of 0.6, pressure of 1 atm, and temperatures of up to 600 K.

  13. Highly sensitive glucose biosensor based on Au-Ni coaxial nanorod array having high aspect ratio.

    Science.gov (United States)

    Hsu, Che-Wei; Wang, Gou-Jen

    2014-06-15

    An effective glucose biosensor requires a sufficient amount of GOx immobilizing on the electrode surface. An electrode of a 3D nanorod array, having a larger surface-to-volume ratio than a 2D nanostructure, can accommodate more GOx molecules to immobilize onto the surface of the nanorods. In this study, a highly sensitive Au-Ni coaxial nanorod array electrode fabricated through the integration of nano electroforming and immersion gold (IG) method for glucose detection was developed. The average diameter of the as-synthesized Ni nanorods and that of the Au-Ni nanorods were estimated to be 150 and 250 nm, respectively; both had a height of 30 μm. The aspect ratio was 120. Compared to that of a flat Au electrode, the effective sensing area was enhanced by 79.8 folds. Actual glucose detections demonstrated that the proposed Au-Ni coaxial nanorod array electrode could operate in a linear range of 27.5 μM-27.5mM with a detection limit of 5.5μM and a very high sensitivity of 769.6 μA mM(-1)cm(-2). Good selectivity of the proposed sensing device was verified by sequential injections of uric acid (UA) and ascorbic acid (AA). Long-term stability was examined through successive detections over a period of 30 days.

  14. Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Koh [National Institute for Advanced Industrial Science and Technology, Molecular Profiling Research Center for Drug Discovery (Japan); Arthanari, Haribabu [Harvard Medical School, Department of Biochemistry and Molecular Pharmacology (United States); Shimada, Ichio, E-mail: shimada@iw-nmr.f.u-tokyo.ac.jp [National Institute for Advanced Industrial Science and Technology, Molecular Profiling Research Center for Drug Discovery (Japan); Wagner, Gerhard, E-mail: gerhard-wagner@hms.harvard.edu [Harvard Medical School, Department of Biochemistry and Molecular Pharmacology (United States)

    2015-12-15

    Detection of {sup 15}N in multidimensional NMR experiments of proteins has sparsely been utilized because of the low gyromagnetic ratio (γ) of nitrogen and the presumed low sensitivity of such experiments. Here we show that selecting the TROSY components of proton-attached {sup 15}N nuclei (TROSY {sup 15}N{sub H}) yields high quality spectra in high field magnets (>600 MHz) by taking advantage of the slow {sup 15}N transverse relaxation and compensating for the inherently low {sup 15}N sensitivity. The {sup 15}N TROSY transverse relaxation rates increase modestly with molecular weight but the TROSY gain in peak heights depends strongly on the magnetic field strength. Theoretical simulations predict that the narrowest line width for the TROSY {sup 15}N{sub H} component can be obtained at 900 MHz, but sensitivity reaches its maximum around 1.2 GHz. Based on these considerations, a {sup 15}N-detected 2D {sup 1}H–{sup 15}N TROSY-HSQC ({sup 15}N-detected TROSY-HSQC) experiment was developed and high-quality 2D spectra were recorded at 800 MHz in 2 h for 1 mM maltose-binding protein at 278 K (τ{sub c} ∼ 40 ns). Unlike for {sup 1}H detected TROSY, deuteration is not mandatory to benefit {sup 15}N detected TROSY due to reduced dipolar broadening, which facilitates studies of proteins that cannot be deuterated, especially in cases where production requires eukaryotic expression systems. The option of recording {sup 15}N TROSY of proteins expressed in H{sub 2}O media also alleviates the problem of incomplete amide proton back exchange, which often hampers the detection of amide groups in the core of large molecular weight proteins that are expressed in D{sub 2}O culture media and cannot be refolded for amide back exchange. These results illustrate the potential of {sup 15}N{sub H}-detected TROSY experiments as a means to exploit the high resolution offered by high field magnets near and above 1 GHz.

  15. Optimal Thermo-Structural Analysis for High Density Package Mounting on Build-up Board

    Science.gov (United States)

    Nakanishi, Tohru; Hase, Tomohiro

    The importance of the high density packaging technology and mounting technology on the printed wiring build-up board has been increased for the consumer electric products. On the other hand, the chance to use the build-up boards for mounting the high density packages has been increased. However, the understanding that the reliability of the solder connection depends on the structure of the package, the motherboard, and the material properties, is not very high. In this paper, the reliability for high density packaging, mounted on the build-up board, is assessed. The compact numerical analysis model for the reliability assessment is suggested and the most reliable packaging design with optimizing each of the parameters is reported. For introduction to the reliability assessment of the FCA attachment, ceramic and silicon are compared as the inter-poser with the parameter of the solder height. The verification of the numerical analysis results using tests on the actual hardware is also shown. And the established numerical analysis model is applied to the study of influence of the copper balance between the front side and the back side copper layers.

  16. High Sensitivity Optomechanical Reference Accelerometer over 10 kHz

    Science.gov (United States)

    2014-06-05

    characterizing fast mechanical dynamics and piezo -electric devices, but typically not both. Yet extremely high resolution maintained over large...applying a ringdown technique in vacuum. To this end, we used a piezo -shaker to excite the oscillator at its resonance frequency and measured the...exponential decay response. The resonance peak was determined by spectral analysis and then honed in by a high resolution function generator driving the piezo

  17. Achieving tunable sensitivity in composite high-energy density materials

    Science.gov (United States)

    Kuklja, Maija M.; Tsyshevsky, Roman V.; Rashkeev, Sergey

    2017-01-01

    Laser irradiation provides a unique opportunity for selective, predictive, and controlled initiation of energetic materials. We propose a consistent micro-scale mechanism of photoexcitation at the interface, formed by a molecular energetic material and a metal oxide. A specific PETN-MgO model composite is used to illustrate and explain seemingly puzzling experiments on selective laser initiation of energetic materials, which reported that the presence of metal oxide additives triggered the photoinitiation by an unusually low energy. We suggest that PETN photodecomposition is catalyzed by oxygen vacancies (F0 centers) at the MgO surface. The proposed model suggests ways to tune sensitivity of energetic molecular materials to photoinitiation. Our quantum-chemical calculations suggest that the structural point defects (e.g., oxygen vacancies) strongly interact with the molecular material (e.g., adsorbed energetic molecules) by inducing a charge transfer at the interface and hence play an imperative role in governing both energy absorption and energy release in the system. Our approach and conclusions provide a solid basis for novel design of energetic interfaces with desired properties and offers a new perspective in the field of explosive materials and devices.

  18. High-sensitivity observations of solar flare decimeter radiation

    Science.gov (United States)

    Benz, A. O.; Messmer, P.; Monstein, C.

    2001-01-01

    A new acousto-optic radio spectrometer has observed the 1-2 GHz radio emission of solar flares with unprecedented sensitivity. The number of detected decimeter type III bursts is greatly enhanced compared to observations by conventional spectrometers observing only one frequency at the time. The observations indicate a large number of electron beams propagating in dense plasmas. For the first time, we report weak, reversed drifting type III bursts at frequencies above simultaneous narrowband decimeter spikes. The type III bursts are reliable signatures of electron beams propagating downward in the corona, apparently away from the source of the spikes. The observations contradict the most popular spike model that places the spike sources at the footpoints of loops. Conspicuous also was an apparent bidirectional type U burst forming a fish-like pattern. It occurs simultaneously with an intense U-burst at 600-370 MHz observed in Tremsdorf. We suggest that it intermodulated with strong terrestrial interference(cellular phones) causing a spurious symmetric pattern in the spectrogram at 1.4 GHz. Symmetric features in the 1-2 GHz range, some already reported in the literature, therefore must be considered with utmost caution.

  19. Response of high-rise and base-isolated buildings to a hypothetical mw 7.0 blind thrust earthquake.

    Science.gov (United States)

    Heaton, T H; Hall, J F; Wald, D J; Halling, M W

    1995-01-13

    High-rise flexible-frame buildings are commonly considered to be resistant to shaking from the largest earthquakes. In addition, base isolation has become increasingly popular for critical buildings that should still function after an earthquake. How will these two types of buildings perform if a large earthquake occurs beneath a metropolitan area? To answer this question, we simulated the near-source ground motions of a M(w) 7.0 thrust earthquake and then mathematically modeled the response of a 20-story steel-frame building and a 3-story base-isolated building. The synthesized ground motions were characterized by large displacement pulses (up to 2 meters) and large ground velocities. These ground motions caused large deformation and possible collapse of the frame building, and they required exceptional measures in the design of the base-isolated building if it was to remain functional.

  20. A Comparative Study of Design Strategies for Energy Efficiency in 6 High-Rise Buildings in Two Different Climates

    NARCIS (Netherlands)

    Raji, B.; Tenpierik, M.J.; Van den Dobbelsteen, A.A.J.F.

    2014-01-01

    Due to the ever growing trend of urbanization and population growth, the construction of high-rise buildings is inevitable and will also continue at an ever increasing pace. However, typical high-rise buildings (the traditional template of a rectilinear, air-conditioned box) are not energy efficient

  1. Controlled synthesis of conjugated microporous polymer films: versatile platforms for highly sensitive and label-free chemo- and biosensing.

    Science.gov (United States)

    Gu, Cheng; Huang, Ning; Gao, Jia; Xu, Fei; Xu, Yanhong; Jiang, Donglin

    2014-05-05

    Conjugated microporous polymers (CMPs), in which rigid building blocks form robust networks, are usually synthesized as insoluble and unprocessable powders. We developed a methodology using electropolymerization for the synthesis of thin CMP films. The thickness of these films is synthetically controllable, ranging from nanometers to micrometers, and they are obtained on substrates or as freestanding films. The CMP films combine a number of striking physical properties, including high porosity, extended π conjugation, facilitated exciton delocalization, and high-rate electron transfer. We explored the CMP films as versatile platforms for highly sensitive and label-free chemo- and biosensing of electron-rich and electron-poor arenes, metal ions, dopamine, and hypochloroic acid, featuring rapid response, excellent selectivity, and robust reusability.

  2. Pressure integration technique for predicting wind-induced response in high-rise buildings

    Directory of Open Access Journals (Sweden)

    Aly Mousaad Aly

    2013-12-01

    Full Text Available This paper presents a procedure for response prediction in high-rise buildings under wind loads. The procedure is illustrated in an application example of a tall building exposed to both cross-wind and along-wind loads. The responses of the building in the lateral directions combined with torsion are estimated simultaneously. Results show good agreement with recent design standards; however, the proposed procedure has the advantages of accounting for complex mode shapes, non-uniform mass distribution, and interference effects from the surrounding. In addition, the technique allows for the contribution of higher modes. For accurate estimation of the acceleration response, it is important to consider not only the first two lateral vibrational modes, but also higher modes. Ignoring the contribution of higher modes may lead to underestimation of the acceleration response; on the other hand, it could result in overestimation of the displacement response. Furthermore, the procedure presented in this study can help decision makers, involved in a tall building design/retrofit to choose among innovative solutions like aerodynamic mitigation, structural member size adjustment, damping enhancement, and/or materials change, with an objective to improve the resiliency and the serviceability under extreme wind actions.

  3. Task Phase Recognition for Highly Mobile Workers in Large Building Complexes

    DEFF Research Database (Denmark)

    Stisen, Allan; Mathisen, Andreas; Krogh, Søren

    2016-01-01

    available for sensing and recognizing the activities and task phases the workers currently perform as such technologies have to be easily deployable and maintainable at a large scale. The methods presented in this paper consist of features that utilize data from sensing systems which are common in large......Being aware of activities of co-workers is a basic and vital mechanism for efficient work in highly distributed work settings. Thus, automatic recognition of the task phases the mobile workers are currently (or have been) in has many applications, e.g., efficient coordination of tasks...... by visualizing coworkers’ task progress, automatic notifications based on context awareness, and record filing of task statuses and completions. This paper presents methods to sense and detect highly mobile workers’ tasks phases in large building complexes. Large building complexes restrict the technologies...

  4. Dynamic Analysis of Flexible Multibody Systems for High-Rise Building Window Cleaning Gondola

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    A virtual prototype of high-rise building window cleaning gondola based on multibody system dynamics software MSC.ADAMS is presented. The rigid bodies are modeled by CAD software and flexible bodies are modeled by discrete beam method. The whole machine's natural characteristics are analyzed and changed to frequency field. According to the results, the dangerous frequencies are avoided and the design can be optimized and the performance can be improved.

  5. A Simulation of an Event Building Network for the CMS High Energy Physics Experiment

    CERN Document Server

    Aziz, S; Brigljevic, V; Bruno, G; Cano, E; Csilling, A; Cittolin, S; Erhan, S; Gigi, D; Glege, F; Gulmini, M; Gutleber, J; Jacobs, C; Kozlovszky, M; Larsen, H; Litmaath, M; Magrans, I; Maron, G; Meijers, F; Meschi, E; Murray, S; O'Dell, V; Oh, A; Orsini, L; Pollet, L; Racz, A; Samyn, D; Scharff-Hansen, P; Sphicas, P; Schwick, C; Suzuki, I; Toniolo, N; Zangrando, L

    2003-01-01

    A simulation of the event building network of the Data Acquisition System of the CMS experiment at the Large Hadron Collider at CERN has been developed. The simulation of this highly complex system allows the validation of the system design and the optimization of its performance. The correctness of the simulation model is verified using measurements from test set-ups and a forecast for the full-scale system is made.

  6. High sensitivity of Giardia duodenalis to tetrahydrolipstatin (orlistat in vitro.

    Directory of Open Access Journals (Sweden)

    Juliane Hahn

    Full Text Available Giardiasis, a gastrointestinal disease caused by Giardia duodenalis, is currently treated mainly with nitroimidazoles, primarily metronidazole (MTZ. Treatment failure rates of up to 20 percent reflect the compelling need for alternative treatment options. Here, we investigated whether orlistat, a drug approved to treat obesity, represents a potential therapeutic agent against giardiasis. We compared the growth inhibitory effects of orlistat and MTZ on a long-term in vitro culture adapted G. duodenalis strain, WB-C6, and on a new isolate, 14-03/F7, from a patient refractory to MTZ treatment using a resazurin assay. The giardiacidal concentration of the drugs and their combined in vitro efficacy was determined by median-effect analysis. Morphological changes after treatment were analysed by light and electron microscopy. Orlistat inhibited the in vitro growth of G. duodenalis at low micromolar concentrations, with isolate 14-03/F7 (IC50(24h = 2.8 µM being more sensitive than WB-C6 (IC50(24h = 6.2 µM. The effect was significantly more potent compared to MTZ (IC50(24h = 4.3 µM and 11.0 µM, respectively and led to specific undulated morphological alterations on the parasite surface. The giardiacidal concentration of orlistat was >14 µM for 14-03/F7 and >43 µM for WB-C6, respectively. Importantly, the combination of both drugs revealed no interaction on their inhibitory effects. We demonstrate that orlistat is a potent inhibitor of G. duodenalis growth in vitro and kills parasites at concentrations achievable in the gut by approved treatment regimens for obesity. We therefore propose to investigate orlistat in controlled clinical studies as a new drug in giardiasis.

  7. High sensitivity of Giardia duodenalis to tetrahydrolipstatin (orlistat) in vitro.

    Science.gov (United States)

    Hahn, Juliane; Seeber, Frank; Kolodziej, Herbert; Ignatius, Ralf; Laue, Michael; Aebischer, Toni; Klotz, Christian

    2013-01-01

    Giardiasis, a gastrointestinal disease caused by Giardia duodenalis, is currently treated mainly with nitroimidazoles, primarily metronidazole (MTZ). Treatment failure rates of up to 20 percent reflect the compelling need for alternative treatment options. Here, we investigated whether orlistat, a drug approved to treat obesity, represents a potential therapeutic agent against giardiasis. We compared the growth inhibitory effects of orlistat and MTZ on a long-term in vitro culture adapted G. duodenalis strain, WB-C6, and on a new isolate, 14-03/F7, from a patient refractory to MTZ treatment using a resazurin assay. The giardiacidal concentration of the drugs and their combined in vitro efficacy was determined by median-effect analysis. Morphological changes after treatment were analysed by light and electron microscopy. Orlistat inhibited the in vitro growth of G. duodenalis at low micromolar concentrations, with isolate 14-03/F7 (IC50(24h) = 2.8 µM) being more sensitive than WB-C6 (IC50(24h) = 6.2 µM). The effect was significantly more potent compared to MTZ (IC50(24h) = 4.3 µM and 11.0 µM, respectively) and led to specific undulated morphological alterations on the parasite surface. The giardiacidal concentration of orlistat was >14 µM for 14-03/F7 and >43 µM for WB-C6, respectively. Importantly, the combination of both drugs revealed no interaction on their inhibitory effects. We demonstrate that orlistat is a potent inhibitor of G. duodenalis growth in vitro and kills parasites at concentrations achievable in the gut by approved treatment regimens for obesity. We therefore propose to investigate orlistat in controlled clinical studies as a new drug in giardiasis.

  8. HIGH SENSITIVE C-REACTIVE PROTEIN IN CEREBROVASCULAR ISCHEMIA

    Directory of Open Access Journals (Sweden)

    Padmalatha

    2016-02-01

    Full Text Available BACKGROUND Cerebrovascular ischemia is recognized as a major health problem, which causes significant morbidity and mortality. The main pathophysiology of ischemic stroke is atherosclerosis of cerebral vessels. Hs-CRP is a sensitive marker of inflammation tissue injury in the arterial wall, which contributes to atherosclerosis. In this study, we aim to investigate the association of hs-CRP in patients with ischemic stroke and to correlate hs-CRP levels with possible risk factors of ischemic stroke and to assess the prognostic value of hs-CRP in ischemic stroke. METHODS In the present case control study after meeting inclusion and exclusion criteria, 50 patients with acute ischemic stroke admitted in the medical ward, King George Hospital, during the period between April 2014 and October 2014 and 40 asymptomatic age and sex matched control subjects were included. RESULTS The mean hs-CRP value in cases is 3.78+5.28mg/dl and in controls is 0.425+0.305mg/dl. Mean hs-CRP value is higher (3.78mg/dl in cases when compared to controls (0.425mg/dl, which is statistically significant. P admitted with severe degree of weakness (0-1/5 power with mean hs-CRP value of 4.28+4.07 without significant improvement in the power at the time of discharge; 8(16%> with mean hs-CRP value of 10.43+7.74 were expired. CONCLUSION Acute ischemic patients had higher mean hs-CRP values when compared to healthy asymptomatic control subjects P0.05. Higher mean hs-CRP values were associated with poor outcome after acute ischemic stroke. P<0.001.

  9. High Sensitivity Indium Phosphide Based Avalanche Photodiode Focal Plane Arrays Project

    Data.gov (United States)

    National Aeronautics and Space Administration — nLight has demonstrated highly-uniform APD arrays based on the highly sensitive InGaAs/InP material system. These results provide great promise for achieving the...

  10. Polycarbonates: a long-term highly sensitive radon monitor

    CERN Document Server

    Pressyanov, D; Poffijn, A; Meesen, G; Deynse, A V

    2000-01-01

    An approach for long-term (either retrospective or prospective) sup 2 sup 2 sup 2 Rn measurements is proposed that is based on the combination of the high radon absorption ability of some polycarbonates with their alpha track-etch properties. The detection limit is projected to be <10 Bq m sup - sup 3 for an exposure time of 20 yr.

  11. Seismic Response of Base-Isolated High-Rise Buildings under Fully Nonstationary Excitation

    Directory of Open Access Journals (Sweden)

    C. F. Ma

    2014-01-01

    Full Text Available Stochastic seismic responses of base-isolated high-rise buildings subjected to fully nonstationary earthquake ground motion are computed by combining the pseudoexcitation and the equivalent linearization methods, and the accuracy of results obtained by the pseudoexcitation method is verified by the Monte Carlo method. The superstructure of a base-isolated high-rise building is represented by a finite element model and a shear-type multi-degree of freedom model, respectively. The influence of the model type and the number of the modes of the superstructure participating in the computation of the dynamic responses of the isolated system has been investigated. The results of a 20-storey, 3D-frame with height to width ratio of 4 show that storey drifts and absolute accelerations of the superstructure for such a high-rise building will be substantially underestimated if the shear-type multi-degree of freedom model is employed or the higher modes of the superstructure are neglected; however, this has nearly no influence on the drift of the base slab.

  12. Forensic entomology of high-rise buildings in Malaysia: Three case reports.

    Science.gov (United States)

    Syamsa, R A; Omar, B; Zuha, R M; Faridah, M N; Swarhib, M S; Hidayatulfathi, O; Shahrom, A W

    2015-06-01

    The distributions of flies are not only confined to ground level but can also be at higher altitudes. Here, we report three forensic cases involving dipterans in high-rise buildings in Kuala Lumpur, Malaysia. Case 1 involved a corpse of adult female found at the top floor of a fifteen-story apartment. Case 2 dealt with a body of a 75-year-old female discovered in a bedroom on the eleventh floor of an eighteen-story building, while Case 3 was a 52-year-old male found in his fifth floor shop house. Interestingly, entomological analysis revealed that all corpses were infested with similar Dipterans: Megaselia scalaris (Loew) (Diptera: Phoridae), Synthesiomyia nudiseta (Wulp) (Diptera: Muscidae) and sarcophagid (Diptera: Sarcophagidae). The first two species were commonly associated with corpses found indoors at ground level. We noted the additional occurrence of blowflies Chrysomya megacephala (Fabricius) (Diptera: Calliphoridae) and Chrysomya rufifacies Macquart (Diptera: Calliphoridae) larvae in Case 2 and Case 3, respectively. Findings from this study are significant as they demonstrate that certain groups of fly can locate dead bodies even in high-rise buildings. Forensic entomofauna research on corpses found at high elevation is scarce and our study has highlighted the peculiarity of the fly species involved in Malaysia.

  13. Building America Case Study: Standard- Versus High-Velocity Air Distribution in High-Performance Townhomes, Denver, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    A. Poerschke, R. Beach, T. Begg

    2017-06-01

    IBACOS investigated the performance of a small-diameter high-velocity heat pump system compared to a conventional system in a new construction triplex townhouse. A ductless heat pump system also was installed for comparison, but the homebuyer backed out because of aesthetic concerns about that system. In total, two buildings, having identical solar orientation and comprised of six townhomes, were monitored for comfort and energy performance.

  14. Mass Spectrometry-based Assay for High Throughput and High Sensitivity Biomarker Verification

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Xuejiang; Tang, Keqi

    2017-06-14

    Searching for disease specific biomarkers has become a major undertaking in the biomedical research field as the effective diagnosis, prognosis and treatment of many complex human diseases are largely determined by the availability and the quality of the biomarkers. A successful biomarker as an indicator to a specific biological or pathological process is usually selected from a large group of candidates by a strict verification and validation process. To be clinically useful, the validated biomarkers must be detectable and quantifiable by the selected testing techniques in their related tissues or body fluids. Due to its easy accessibility, protein biomarkers would ideally be identified in blood plasma or serum. However, most disease related protein biomarkers in blood exist at very low concentrations (<1ng/mL) and are “masked” by many none significant species at orders of magnitude higher concentrations. The extreme requirements of measurement sensitivity, dynamic range and specificity make the method development extremely challenging. The current clinical protein biomarker measurement primarily relies on antibody based immunoassays, such as ELISA. Although the technique is sensitive and highly specific, the development of high quality protein antibody is both expensive and time consuming. The limited capability of assay multiplexing also makes the measurement an extremely low throughput one rendering it impractical when hundreds to thousands potential biomarkers need to be quantitatively measured across multiple samples. Mass spectrometry (MS)-based assays have recently shown to be a viable alternative for high throughput and quantitative candidate protein biomarker verification. Among them, the triple quadrupole MS based assay is the most promising one. When it is coupled with liquid chromatography (LC) separation and electrospray ionization (ESI) source, a triple quadrupole mass spectrometer operating in a special selected reaction monitoring (SRM) mode

  15. Microstructure-Sensitive Modeling of High Cycle Fatigue (Preprint)

    Science.gov (United States)

    2009-03-01

    history ( carburization and shot peening) and resulting residual stresses are considered in the case of subsurface crack formation at primary inclusions...experimental responses for known microstructures. Effects of process history ( carburization and shot peening) and resulting residual stresses are considered...nonmetallic inclusions. 3. HCF Crack Formation in Carburized and Shot Peened Martensitic Gear Steel High strength low carbon martensitic gear steel is a

  16. A highly selective and sensitive fluorescent chemosensor for Zn2+

    Institute of Scientific and Technical Information of China (English)

    Xiu Ying Zhang; Zuo Hui Wang; Lin Yang

    2008-01-01

    A new selective Zn2+ fluorescent chemosensor,o-vanillin-4-ethoxybenzoylhydrazone(1),was designed and prepared.Free 1 mainly displayed very weak fluorescence at 480 nm upone xcitation at 403 nln.It displayed high selectivity for Zn2+ and had a 518-fold fluorescent enhancement upon binding of Zn2+.while the other cation ions had only little influence on the fluorescence of 1.Mechanism of enhancement of 1's fluorescence by Zn2+ was briefly discussed.

  17. Highly sensitive bolometers for rare alpha decay studies

    Directory of Open Access Journals (Sweden)

    Gironi L.

    2014-03-01

    Full Text Available High resolution detectors able to identify background events are very appealing in the study of rare nuclear processes. Scintillating bolometers featuring simultaneous read-out of heat and scintillation signals, can effectively address this problem thanks to the possibility to discriminate different ionizing particles and achieve background free experiments. With this technique it has already been possible to measure rare alpha decays never observed before or improve by orders of magnitude the existing limits.

  18. An Adaptive Intelligent Integrated Lighting Control Approach for High-Performance Office Buildings

    Science.gov (United States)

    Karizi, Nasim

    An acute and crucial societal problem is the energy consumed in existing commercial buildings. There are 1.5 million commercial buildings in the U.S. with only about 3% being built each year. Hence, existing buildings need to be properly operated and maintained for several decades. Application of integrated centralized control systems in buildings could lead to more than 50% energy savings. This research work demonstrates an innovative adaptive integrated lighting control approach which could achieve significant energy savings and increase indoor comfort in high performance office buildings. In the first phase of the study, a predictive algorithm was developed and validated through experiments in an actual test room. The objective was to regulate daylight on a specified work plane by controlling the blind slat angles. Furthermore, a sensor-based integrated adaptive lighting controller was designed in Simulink which included an innovative sensor optimization approach based on genetic algorithm to minimize the number of sensors and efficiently place them in the office. The controller was designed based on simple integral controllers. The objective of developed control algorithm was to improve the illuminance situation in the office through controlling the daylight and electrical lighting. To evaluate the performance of the system, the controller was applied on experimental office model in Lee et al.'s research study in 1998. The result of the developed control approach indicate a significantly improvement in lighting situation and 1-23% and 50-78% monthly electrical energy savings in the office model, compared to two static strategies when the blinds were left open and closed during the whole year respectively.

  19. Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells

    Science.gov (United States)

    Tan, Juntao; Yang, Nuo; Hu, Zixi; Su, Jing; Zhong, Jianhong; Yang, Yang; Yu, Yating; Zhu, Jianmeng; Xue, Dabin; Huang, Yingying; Lai, Zongqiang; Huang, Yong; Lu, Xiaoling; Zhao, Yongxiang

    2016-06-01

    A simple, highly sensitive method to detect leukemia cells has been developed based on aptamer-modified fluorescent silica nanoparticles (FSNPs). In this strategy, the amine-labeled Sgc8 aptamer was conjugated to carboxyl-modified FSNPs via amide coupling between amino and carboxyl groups. Sensitivity and specificity of Sgc8-FSNPs were assessed using flow cytometry and fluorescence microscopy. These results showed that Sgc8-FSNPs detected leukemia cells with high sensitivity and specificity. Aptamer-modified FSNPs hold promise for sensitive and specific detection of leukemia cells. Changing the aptamer may allow the FSNPs to detect other types of cancer cells.

  20. Highly sensitive passive radio frequency identification based sensor systems.

    Science.gov (United States)

    Wissenwasser, J; Vellekoop, M; Heer, R

    2010-02-01

    A novel platform for sensor applications based on radio frequency (rf) identification technology, where passive tags are powered by the rf-field of a reader, is presented. The sophisticated energy harvesting system of the tag enables a blanking of the rf-field for a defined period, while supplying the tag electronics with a highly stable voltage and a power of 25 mW for 100 ms. During this time, span measurements can be performed without interferences of the rf-field. The presented tags work without batteries and are designed for impedance measurements on microbiological cell cultures under physiological relevant conditions as well as in harsh environments.

  1. Highly sensitive passive radio frequency identification based sensor systems

    Science.gov (United States)

    Wissenwasser, J.; Vellekoop, M.; Heer, R.

    2010-02-01

    A novel platform for sensor applications based on radio frequency (rf) identification technology, where passive tags are powered by the rf-field of a reader, is presented. The sophisticated energy harvesting system of the tag enables a blanking of the rf-field for a defined period, while supplying the tag electronics with a highly stable voltage and a power of 25 mW for 100 ms. During this time, span measurements can be performed without interferences of the rf-field. The presented tags work without batteries and are designed for impedance measurements on microbiological cell cultures under physiological relevant conditions as well as in harsh environments.

  2. Purification of ethanol for highly sensitive self-assembly experiments

    Directory of Open Access Journals (Sweden)

    Kathrin Barbe

    2014-08-01

    Full Text Available Ethanol is the preferred solvent for the formation of self-assembled monolayers (SAMs of thiolates on gold. By applying a thin film sensor system, we could demonstrate that even the best commercial qualities of ethanol contain surface-active contaminants, which can compete with the desired thiolates for surface sites. Here we present that gold nanoparticles deposited onto zeolite X can be used to remove these contaminants by chemisorption. This nanoparticle-impregnated zeolite does not only show high capacities for surface-active contaminants, such as thiols, but can be fully regenerated via a simple pyrolysis protocol.

  3. Dynamics and sensitivity analysis of high-frequency conduction block

    Science.gov (United States)

    Ackermann, D. Michael; Bhadra, Niloy; Gerges, Meana; Thomas, Peter J.

    2011-10-01

    The local delivery of extracellular high-frequency stimulation (HFS) has been shown to be a fast acting and quickly reversible method of blocking neural conduction and is currently being pursued for several clinical indications. However, the mechanism for this type of nerve block remains unclear. In this study, we investigate two hypotheses: (1) depolarizing currents promote conduction block via inactivation of sodium channels and (2) the gating dynamics of the fast sodium channel are the primary determinate of minimal blocking frequency. Hypothesis 1 was investigated using a combined modeling and experimental study to investigate the effect of depolarizing and hyperpolarizing currents on high-frequency block. The results of the modeling study show that both depolarizing and hyperpolarizing currents play an important role in conduction block and that the conductance to each of three ionic currents increases relative to resting values during HFS. However, depolarizing currents were found to promote the blocking effect, and hyperpolarizing currents were found to diminish the blocking effect. Inward sodium currents were larger than the sum of the outward currents, resulting in a net depolarization of the nodal membrane. Our experimental results support these findings and closely match results from the equivalent modeling scenario: intra-peritoneal administration of the persistent sodium channel blocker ranolazine resulted in an increase in the amplitude of HFS required to produce conduction block in rats, confirming that depolarizing currents promote the conduction block phenomenon. Hypothesis 2 was investigated using a spectral analysis of the channel gating variables in a single-fiber axon model. The results of this study suggested a relationship between the dynamical properties of specific ion channel gating elements and the contributions of corresponding conductances to block onset. Specifically, we show that the dynamics of the fast sodium inactivation gate are

  4. A compact high-sensitivity heterodyne interferometer for industrial metrology

    Science.gov (United States)

    Schuldt, Thilo; Gohlke, Martin; Weise, Dennis; Peters, Achim; Johann, Ulrich; Braxmaier, Claus

    2008-04-01

    For translation and tilt metrology, we developed a compact fiber-coupled polarizing heterodyne interferometer which is based on a highly symmetric design where both, measurement and reference beam have similar optical pathlengths and the same frequency and polarization. The method of differential wavefront sensing is implemented for tilt measurement. With this setup we reached noise levels below 5 pm/square root of Hz; Hz in translation and below 10 nrad/square root of Hz; in tilt measurement, both for frequencies above 10-2 Hz. While this setup is developed with respect to the requirements of the LISA (Laser Interferometer Space Antenna) space mission, we here present the current status of its adoption to industrial applications. We currently design a very compact and quasi-monolithic setup of the interferometer sensor head based on ultra-low expansion glass material. The resulting compact and robust sensor head can be used for nano-positioning control. We also plan to implement a scan of the measurement beam over the surface under investigation enabling high resolution 3D profilometry and surface property measurements (i. e. roughness, evenness and roundness). The dedicated low-noise (piezo-electric actuator in the measurement beam of the interferometer will be realized using integrated micro-system technology and can either be implemented in one or two dimensions.

  5. Highly sensitive thermoluminescent carbon doped nanoporous aluminium oxide detectors.

    Science.gov (United States)

    de Azevedo, W M; de Oliveira, G B; da Silva, E F; Khoury, H J; Oliveira de Jesus, E F

    2006-01-01

    In this work we present the synthesis, characterisation and the thermoluminescence (TL) response of nanoporous carbon doped aluminium oxide Al2O3:C produced by anodic oxidation of aluminium in organic and inorganic solvents. The X-ray and scanning electron microscopy (SEM) measurements reveal that the synthesised samples are amorphous and present highly ordered structures with uniform pore distribution with diameter of the order 50 nm. The photoluminescence and spectroscopic analysis in the visible and infrared regions show that the luminescence properties presented by the samples prepared in organic acid are due to carboxylate species, incorporated in anodic alumina films during the synthesis process. After an annealing treatment, part of the incorporated species decomposes and is incorporated into the structure of the aluminium oxide yielding a highly thermoluminescent detector (TL) . The results for X-ray irradiation in the range from 21 to 80 keV indicate a linear TL response with the dose in the range from 5 mGy to 1 Gy, suggesting that nanoporous aluminium oxide produced in the present route of synthesis is a suitable detector for radiation measurements.

  6. Porous tungsten oxide nanoflakes for highly alcohol sensitive performance.

    Science.gov (United States)

    Xiao, J; Liu, P; Liang, Y; Li, H B; Yang, G W

    2012-11-21

    Porous tungsten oxide (WO(3)) nanoflakes have been synthesized by a simple and green approach in an ambient environment. As a precursor solution a polycrystalline hydrated tungstite (H(2)WO(4)·H(2)O) nanoparticles colloid was first prepared by pulsed-laser ablation of a tungsten target in water. The H(2)WO(4)·H(2)O nanoflakes were produced by 72 h aging treatment at room temperature. Finally, porous WO(3) nanoflakes were synthesized by annealing at 800 °C for 4 h. Considering the large surface-to-volume ratio of porous nanoflakes, a porous WO(3) nanoflake gas sensor was fabricated, which exhibits an excellent sensor response performance to alcohol concentrations in the range of 20 to 600 ppm under low working temperature. This high response was attributed to the highly crystalline and porous flake-like morphology, which leads to effective adsorption and desorption, and provides more active sites for the gas molecules' reaction. These findings showed that the porous tungsten oxide nanoflake has great potential in gas-sensing performance.

  7. Highly sensitive temperature sensor based on an isopropanol-filled photonic crystal fiber long period grating

    Science.gov (United States)

    Du, Chao; Wang, Qi; Zhao, Yong; Li, Jin

    2017-03-01

    A high sensitivity measurement method for temperature has been proposed and investigated based on an isopropanol-filled photonic crystal fiber long period grating (PCF-LPG). Due to the high thermo-optic coefficient (TOC) of isopropanol, the sensitivity of the proposed temperature sensor could be effectively improved by filling isopropanol in the air waveguides of PCF. It can be found that the resonant dip will be split in two dips after filling isopropanol and the two dips have different sensitivities to surrounding temperature. Because of PCF-LPG is sensitive to the refractive index (RI) of internal filled liquid, the isopropanol-filled PCF-LPG temperature sensor has a high sensitivities of 1.356 nm/°C in the range of 20-50 °C. The simplicity and the excellent performance of our proposed device make it potential for the applications of high-precision temperature measurement is required.

  8. Analysis of wind-induced vibrations in high-rise buildings

    DEFF Research Database (Denmark)

    Persson, Peter; Austrell, Per-Erik; Kirkegaard, Poul Henning

    2016-01-01

    Buildings are getting taller due to increased urbanisation and densification of cities. More advanced construction methods and the desire to construct impressive buildings is also supporting the trend. Due to their inherent slenderness resulting in low eigenfrequencies, these buildings...

  9. Contributing to Net Zero Building: High Energy Efficient EIFS Wall Systems

    Energy Technology Data Exchange (ETDEWEB)

    Carbary, Lawrence D. [Dow Corning Corporation; Perkins, Laura L. [Dow Corning Corporation; Serino, Roland [Dryvit Systems, Inc; Preston, Bill [Dryvit Systems, Inc; Kosny, Jan [Fraunhofer USA, Inc. CSE

    2014-01-29

    The team led by Dow Corning collaborated to increase the thermal performance of exterior insulation and finishing systems (EIFS) to reach R-40 performance meeting the needs for high efficiency insulated walls. Additionally, the project helped remove barriers to using EIFS on retrofit commercial buildings desiring high insulated walls. The three wall systems developed within the scope of this project provide the thermal performance of R-24 to R-40 by incorporating vacuum insulation panels (VIPs) into an expanded polystyrene (EPS) encapsulated vacuum insulated sandwich element (VISE). The VISE was incorporated into an EIFS as pre-engineered insulation boards. The VISE is installed using typical EIFS details and network of trained installers. These three wall systems were tested and engineered to be fully code compliant as an EIFS and meet all of the International Building Code structural, durability and fire test requirements for a code compliant exterior wall cladding system. This system is being commercialized under the trade name Dryvit® Outsulation® HE system. Full details, specifications, and application guidelines have been developed for the system. The system has been modeled both thermally and hygrothermally to predict condensation potential. Based on weather models for Baltimore, MD; Boston, MA; Miami, FL; Minneapolis, MN; Phoenix, AZ; and Seattle, WA; condensation and water build up in the wall system is not a concern. Finally, the team conducted a field trial of the system on a building at the former Brunswick Naval Air Station which is being redeveloped by the Midcoast Regional Redevelopment Authority (Brunswick, Maine). The field trial provided a retrofit R-30 wall onto a wood frame construction, slab on grade, 1800 ft2 building, that was monitored over the course of a year. Simultaneous with the façade retrofit, the building’s windows were upgraded at no charge to this program. The retrofit building used 49% less natural gas during the winter of

  10. A novel high resolution, high sensitivity SPECT detector for molecular imaging of cardiovascular diseases

    Science.gov (United States)

    Cusanno, F.; Argentieri, A.; Baiocchi, M.; Colilli, S.; Cisbani, E.; De Vincentis, G.; Fratoni, R.; Garibaldi, F.; Giuliani, F.; Gricia, M.; Lucentini, M.; Magliozzi, M. L.; Majewski, S.; Marano, G.; Musico, P.; Musumeci, M.; Santavenere, F.; Torrioli, S.; Tsui, B. M. W.; Vitelli, L.; Wang, Y.

    2010-05-01

    Cardiovascular diseases are the most common cause of death in western countries. Understanding the rupture of vulnerable atherosclerotic plaques and monitoring the effect of innovative therapies of heart failure is of fundamental importance. A flexible, high resolution, high sensitivity detector system for molecular imaging with radionuclides on small animal models has been designed for this aim. A prototype has been built using tungsten pinhole and LaBr3(Ce) scintillator coupled to Hamamatsu Flat Panel PMTs. Compact individual-channel readout has been designed, built and tested. Measurements with phantoms as well as pilot studies on mice have been performed, the results show that the myocardial perfusion in mice can be determined with sufficient precision. The detector will be improved replacing the Hamamatsu Flat Panel with Silicon Photomultipliers (SiPMs) to allow integration of the system with MRI scanners. Application of LaBr3(Ce) scintillator coupled to photosensor with high photon detection efficiency and excellent energy resolution will allow dual-label imaging to monitor simultaneously the cardiac perfusion and the molecular targets under investigation during the heart therapy.

  11. Color Sensitivity Multiple Exposure Fusion using High Dynamic Range Image

    Directory of Open Access Journals (Sweden)

    Varsha Borole

    2014-02-01

    Full Text Available In this paper, we present a high dynamic range imaging (HDRI method using a capturing camera image using normally exposure, over exposure and under exposure. We make three different images from a multiple input image using local histogram stretching. Because the proposed method generated three histogram-stretched images from a multiple input image, ghost artifacts that are the result of the relative motion between the camera and objects during exposure time, are inherently removed. Therefore, the proposed method can be applied to a consumer compact camera to provide the ghost artifacts free HDRI. Experiments with several sets of test images with different exposures show that the proposed method gives a better performance than existing methods in terms of visual results and computation time.

  12. SPECIFICATIONS FOR HIGH TEMPERATURE LATTICE TEST REACTOR BUILDING 318 PROJECT CAH-100

    Energy Technology Data Exchange (ETDEWEB)

    Vitro Engineering Company

    1964-07-15

    This is the specifications for the High Temperature Lattice Test Reactor Building 318 and it is divided into the following 21 divisions or chapters: (1) Excavating, Backfill & Grading; (2) Reinforced Concrete; (3) Masonry; (4) Structural Steel & Miscellaneous Metal Items, Contents - Division V; (5) Plumbing, Process & Service Piping; (6) Welding; (7) Insulated Metal Siding; (8) Roof Decks & Roofing; (9) Plaster Partitions & Ceiling; (10) Standard Doors, Windows & Hardware; (11) Shielding Doors; (12) Sprinkler System & Fire Extinguishers, Contents - Division XIII; (13) Heating, Ventilating & Air Conditioning; (14) Painting, Protective Coating & Floor Covering, Contents - Division XV; (15) Electrical; (16) Communications & Alarm Systems; (17) Special Equipment & Furnishings; (18) Overhead Bridge Crane; (19) Prefabricated Steel Building; (20) Paved Drive; and (21) Landscaping & Irrigation Sprinklers.

  13. High sensitivity, wide coverage, and high-resolution NIR non-cryogenic spectrograph, WINERED

    Science.gov (United States)

    Ikeda, Yuji; Kobayashi, Naoto; Kondo, Sohei; Otsubo, Shogo; Hamano, Satoshi; Sameshima, Hiroaki; Yoshikawa, Tomoshiro; Fukue, Kei; Nakanishi, Kenshi; Kawanishi, Takafumi; Nakaoka, Tetsuya; Kinoshita, Masaomi; Kitano, Ayaka; Asano, Akira; Takenaka, Keiichi; Watase, Ayaka; Mito, Hiroyuki; Yasui, Chikako; Minami, Atsushi; Izumu, Natsuko; Yamamoto, Ryo; Mizumoto, Misaki; Arasaki, Takayuki; Arai, Akira; Matsunaga, Noriyuki; Kawakita, Hideyo

    2016-08-01

    Near-infrared (NIR) high-resolution spectroscopy is a fundamental observational method in astronomy. It provides significant information on the kinematics, the magnetic fields, and the chemical abundances, of astronomical objects embedded in or behind the highly extinctive clouds or at the cosmological distances. Scientific requirements have accelerated the development of the technology required for NIR high resolution spectrographs using 10 m telescopes. WINERED is a near-infrared (NIR) high-resolution spectrograph that is currently mounted on the 1.3 m Araki telescope of the Koyama Astronomical Observatory in Kyoto-Sangyo University, Japan, and has been successfully operated for three years. It covers a wide wavelength range from 0.90 to 1.35 μm (the z-, Y-, and J-bands) with a spectral resolution of R = 28,000 (Wide-mode) and R = 80,000 (Hires-Y and Hires-J modes). WINERED has three distinctive features: (i) optics with no cold stop, (ii) wide spectral coverage, and (iii) high sensitivity. The first feature, originating from the Joyce proposal, was first achieved by WINERED, with a short cutoff infrared array, cold baffles, and custom-made thermal blocking filters, and resulted in reducing the time for development, alignment, and maintenance, as well as the total cost. The second feature is realized with the spectral coverage of Δλ/λ 1/6 in a single exposure. This wide coverage is realized by a combination of a decent optical design with a cross-dispersed echelle and a large format array (2k x 2k HAWAII- 2RG). The Third feature, high sensitivity, is achieved via the high-throughput optics (>60 %) and the very low noise of the system. The major factors affecting the high throughput are the echelle grating and the VPH cross-disperser with high diffraction efficiencies of 83 % and 86 %, respectively, and the high QE of HAWAII-2RG (83 % at 1.23 μm). The readout noise of the electronics and the ambient thermal background radiation at longer wavelengths could be

  14. Analysis of wind-induced vibrations in high-rise buildings

    DEFF Research Database (Denmark)

    Persson, Peter; Austrell, Per-Erik; Kirkegaard, Poul Henning;

    2016-01-01

    Buildings are getting taller due to increased urbanisation and densification of cities. More advanced construction methods and the desire to construct impressive buildings is also supporting the trend. Due to their inherent slenderness resulting in low eigenfrequencies, these buildings are suscep......Buildings are getting taller due to increased urbanisation and densification of cities. More advanced construction methods and the desire to construct impressive buildings is also supporting the trend. Due to their inherent slenderness resulting in low eigenfrequencies, these buildings...

  15. Building Science-Relevant Literacy with Technical Writing in High School

    Energy Technology Data Exchange (ETDEWEB)

    Girill, T R

    2006-06-02

    By drawing on the in-class work of an on-going literacy outreach project, this paper explains how well-chosen technical writing activities can earn time in high-school science courses by enabling underperforming students (including ESL students) to learn science more effectively. We adapted basic research-based text-design and usability techniques into age-appropriate exercises and cases using the cognitive apprenticeship approach. This enabled high-school students, aided by explicit guidelines, to build their cognitive maturity, learn how to craft good instructions and descriptions, and apply those skills to better note taking and technical talks in their science classes.

  16. Effects of intrinsic magnetostriction on tube-topology magnetoelectric sensors with high magnetic field sensitivity

    Science.gov (United States)

    Gillette, Scott M.; Fitchorov, Trifon; Obi, Ogheneyunume; Jiang, Liping; Hao, Hongbo; Wu, Shuangxia; Chen, Yajie; Harris, Vincent G.

    2014-05-01

    Three quasi-one-dimensional magnetoelectric (ME) magnetic field sensors, each with a different magnetostrictive wire material, were investigated in terms of sensitivity and noise floor. Magnetostrictive Galfenol, iron-cobalt-vanadium, and iron-nickel wires were examined. Sensitivity profiles, hysteresis effects, and noise floor measurements for both optimally biased and zero-biased conditions are presented. The FeNi wire (FN) exhibits high sensitivity (5.36 mV/Oe) at bias fields below 22 Oe and an optimal bias of 10 Oe, whereas FeGa wire (FG) exhibits higher sensitivity (6.89 mW/Oe) at bias fields >22 Oe. The sensor of FeCoV wire (FC) presents relatively low sensitivity (2.12 mV/Oe), due to low magnetostrictive coefficient. Each ME tube-topology sensor demonstrates relatively high sensitivity at zero bias field, which results from a magnetic shape anisotropy and internal strain of the thin magnetostrictive wire.

  17. High-efficient dye-sensitized solar cell based on novel TiO2 nanorod/nanoparticle bilayer electrode

    Directory of Open Access Journals (Sweden)

    Hoda Hafez

    2010-08-01

    Full Text Available Hoda Hafez1,2, Zhang Lan2, Qinghua Li2, Jihuai Wu21Environmental Studies and Research Institute, Minoufiya University, Sadat City, Egypt, 2Institute of Materials Physical Chemistry, Huaqiao University, Quanzhou, ChinaAbstract: High light-to-energy conversion efficiency was achieved by applying novel TiO2 nanorod/nanoparticle (NR/NP bilayer electrode in the N719 dye-sensitized solar cells. The short-circuit current density (JSC, the open-circuit voltage (VOC, the fill factor (FF, and the overall efficiency (η were 14.45 mA/cm2, 0.756 V, 0.65, and 7.1%, respectively. The single-crystalline TiO2 NRs with length 200–500 nm and diameter 30–50 nm were prepared by simple hydrothermal methods. The dye-sensitized solar cells with pure TiO2 NR and pure TiO2 NP electrodes showed only a lower light-to-electricity conversion efficiency of 4.4% and 5.8%, respectively, compared with single-crystalline TiO2 NRs. This can be attributed to the new NR/NP bilayer design that can possess the advantages of both building blocks, ie, the high surface area of NP aggregates and rapid electron transport rate and the light scattering effect of single-crystalline NRs.Keywords: dye-sensitized solar cell, TiO2 nanorod, bilayer electrode

  18. Nanowire-templated microelectrodes for high-sensitivity pH detection

    DEFF Research Database (Denmark)

    Antohe, V.A.; Radu, Adrian; Mátéfi-Tempfli, Mária

    2009-01-01

    A highly sensitive pH capacitive sensor has been designed by confined growth of vertically aligned nanowire arrays on interdigited microelectrodes. The active surface of the device has been functionalized with an electrochemical pH transducer (polyaniline). We easily tune the device features...... by combining lithographic techniques with electrochemical synthesis. The reported electrical LC resonance measurements show considerable sensitivity enhancement compared to conventional capacitive pH sensors realized with microfabricated interdigited electrodes. The sensitivity can be easily improved...

  19. Automated Building Extraction from High-Resolution Satellite Imagery in Urban Areas Using Structural, Contextual, and Spectral Information

    Directory of Open Access Journals (Sweden)

    Curt H. Davis

    2005-08-01

    Full Text Available High-resolution satellite imagery provides an important new data source for building extraction. We demonstrate an integrated strategy for identifying buildings in 1-meter resolution satellite imagery of urban areas. Buildings are extracted using structural, contextual, and spectral information. First, a series of geodesic opening and closing operations are used to build a differential morphological profile (DMP that provides image structural information. Building hypotheses are generated and verified through shape analysis applied to the DMP. Second, shadows are extracted using the DMP to provide reliable contextual information to hypothesize position and size of adjacent buildings. Seed building rectangles are verified and grown on a finely segmented image. Next, bright buildings are extracted using spectral information. The extraction results from the different information sources are combined after independent extraction. Performance evaluation of the building extraction on an urban test site using IKONOS satellite imagery of the City of Columbia, Missouri, is reported. With the combination of structural, contextual, and spectral information, 72.7% of the building areas are extracted with a quality percentage 58.8%.

  20. Hypoxia-sensitive reporter system for high-throughput screening.

    Science.gov (United States)

    Tsujita, Tadayuki; Kawaguchi, Shin-ichi; Dan, Takashi; Baird, Liam; Miyata, Toshio; Yamamoto, Masayuki

    2015-01-01

    The induction of anti-hypoxic stress enzymes and proteins has the potential to be a potent therapeutic strategy to prevent the progression of ischemic heart, kidney or brain diseases. To realize this idea, small chemical compounds, which mimic hypoxic conditions by activating the PHD-HIF-α system, have been developed. However, to date, none of these compounds were identified by monitoring the transcriptional activation of hypoxia-inducible factors (HIFs). Thus, to facilitate the discovery of potent inducers of HIF-α, we have developed an effective high-throughput screening (HTS) system to directly monitor the output of HIF-α transcription. We generated a HIF-α-dependent reporter system that responds to hypoxic stimuli in a concentration- and time-dependent manner. This system was developed through multiple optimization steps, resulting in the generation of a construct that consists of the secretion-type luciferase gene (Metridia luciferase, MLuc) under the transcriptional regulation of an enhancer containing 7 copies of 40-bp hypoxia responsive element (HRE) upstream of a mini-TATA promoter. This construct was stably integrated into the human neuroblastoma cell line, SK-N-BE(2)c, to generate a reporter system, named SKN:HRE-MLuc. To improve this system and to increase its suitability for the HTS platform, we incorporated the next generation luciferase, Nano luciferase (NLuc), whose longer half-life provides us with flexibility for the use of this reporter. We thus generated a stably transformed clone with NLuc, named SKN:HRE-NLuc, and found that it showed significantly improved reporter activity compared to SKN:HRE-MLuc. In this study, we have successfully developed the SKN:HRE-NLuc screening system as an efficient platform for future HTS.

  1. Connections in Precast Buildings using Ultra High-Strength Fibre Reinforced Concrete

    DEFF Research Database (Denmark)

    Jensen, Bjarne Chr.; Jensen, Lars Rom; Hansen, F. Toft

    1995-01-01

    Precast elements have been used for decades in the building industry. Main reason for this are reduction in price, reduction in erection time, and increase of the quality as production in factories often reduce the possibility of faults. Since the beginning of the 70's, we have in Denmark made...... for the building industry. The Building Department of the Education Ministry has initiated such a development, and very simple building systems will be used for the next building complex at Aalborg University. The partners who did the development for the Building Department, are Carl Bro Group, Dall & Lindhardtsen...... several attempts to change from large panel buildings into systems which allow much more flexibility in the use of the building including changes during the lifetime of the building. Column/beam/slab building systems have been introduced, but the flexibility is still limited. Column/slab building systems...

  2. Sensory Processing Sensitivity: Factors of the Highly Sensitive Person Scale and Their relationships to Personality and Subjective Health Complaints.

    Science.gov (United States)

    Listou Grimen, Hanne; Diseth, Åge

    2016-12-01

    The aim of the present study was to examine the factor structure of a Norwegian version of the Highly Sensitive Person Scale (HSPS) and to investigate how sensory processing sensitivity (SPS) is related to personality traits of neuroticism, extraversion, and openness and to subjective health complaints (SHC) in a sample of 167 undergraduate psychology students. The results showed that the variance in a shortened version of the HSPS was best described by three separate factors: ease of excitation (EOE), aesthetic sensitivity (AES), and low sensory threshold (LST). Furthermore, the result showed than an overall SPS factor (EOE, LST, and AES combined) was predicted positively by neuroticism and openness and negatively by extraversion. With respect to SHC, the results showed that EOE and LST were positively associated with psychological health complaints. However, the personality trait of neuroticism contributed more than the SPS factors as predictor of SHC. In conclusion, the present study supported a shortened version of the HSPS and its relation to personality factors and SHC.

  3. Enhanced laboratory sensitivity to variation of the fine-structure constant using highly charged ions.

    Science.gov (United States)

    Berengut, J C; Dzuba, V A; Flambaum, V V

    2010-09-17

    We study atomic systems that are in the frequency range of optical atomic clocks and have enhanced sensitivity to potential time variation of the fine-structure constant α. The high sensitivity is due to coherent contributions from three factors: high nuclear charge Z, high ionization degree, and significant differences in the configuration composition of the states involved. Configuration crossing keeps the frequencies in the optical range despite the large ionization energies. We discuss a few promising examples that have the largest α sensitivities seen in atomic systems.

  4. High Sensitivity 1-D and 2-D Microwave Spectroscopy via Cryogenic Buffer Gas Cooling

    Science.gov (United States)

    Patterson, David; Eibenberger, Sandra

    2017-06-01

    All rotationally resolved spectroscopic methods rely on sources of cold molecules. For the last three decades, the workhorse technique for producing highly supersaturated samples of cold molecules has been the pulsed supersonic jet. We present here progress on our alternative method, cryogenic buffer gas cooling. Our high density, continuous source, and low noise temperature allow us to record microwave spectra at unprecedented sensitivity, with a dynamic range in excess of 10^6 achievable in a few minutes of integration time. This high sensitivity enables new protocols in both 1-D and 2-D microwave spectroscopy, including sensitive chiral analysis via nonlinear three wave mixing and applications as an analytical chemistry tool

  5. Highly sensitive surface plasmon resonance chemical sensor based on Goos-Hanchen effects

    Science.gov (United States)

    Yin, Xiaobo; Hesselink, Lambertus

    2006-08-01

    The resonance enhanced Goos-Hanchen shifts at attenuated total internal reflection enables the possibility for highly sensitive surface plasmon resonance sensor. The observed giant displacements result from the singular phase retardation at the resonance where the phase is continuous but changes dramatically. The phenomenon is proposed for chemical sensing and the superior sensitivity is demonstrated.

  6. A Saliency Guided Semi-Supervised Building Change Detection Method for High Resolution Remote Sensing Images

    Directory of Open Access Journals (Sweden)

    Bin Hou

    2016-08-01

    Full Text Available Characterizations of up to date information of the Earth’s surface are an important application providing insights to urban planning, resources monitoring and environmental studies. A large number of change detection (CD methods have been developed to solve them by utilizing remote sensing (RS images. The advent of high resolution (HR remote sensing images further provides challenges to traditional CD methods and opportunities to object-based CD methods. While several kinds of geospatial objects are recognized, this manuscript mainly focuses on buildings. Specifically, we propose a novel automatic approach combining pixel-based strategies with object-based ones for detecting building changes with HR remote sensing images. A multiresolution contextual morphological transformation called extended morphological attribute profiles (EMAPs allows the extraction of geometrical features related to the structures within the scene at different scales. Pixel-based post-classification is executed on EMAPs using hierarchical fuzzy clustering. Subsequently, the hierarchical fuzzy frequency vector histograms are formed based on the image-objects acquired by simple linear iterative clustering (SLIC segmentation. Then, saliency and morphological building index (MBI extracted on difference images are used to generate a pseudo training set. Ultimately, object-based semi-supervised classification is implemented on this training set by applying random forest (RF. Most of the important changes are detected by the proposed method in our experiments. This study was checked for effectiveness using visual evaluation and numerical evaluation.

  7. A Saliency Guided Semi-Supervised Building Change Detection Method for High Resolution Remote Sensing Images.

    Science.gov (United States)

    Hou, Bin; Wang, Yunhong; Liu, Qingjie

    2016-08-27

    Characterizations of up to date information of the Earth's surface are an important application providing insights to urban planning, resources monitoring and environmental studies. A large number of change detection (CD) methods have been developed to solve them by utilizing remote sensing (RS) images. The advent of high resolution (HR) remote sensing images further provides challenges to traditional CD methods and opportunities to object-based CD methods. While several kinds of geospatial objects are recognized, this manuscript mainly focuses on buildings. Specifically, we propose a novel automatic approach combining pixel-based strategies with object-based ones for detecting building changes with HR remote sensing images. A multiresolution contextual morphological transformation called extended morphological attribute profiles (EMAPs) allows the extraction of geometrical features related to the structures within the scene at different scales. Pixel-based post-classification is executed on EMAPs using hierarchical fuzzy clustering. Subsequently, the hierarchical fuzzy frequency vector histograms are formed based on the image-objects acquired by simple linear iterative clustering (SLIC) segmentation. Then, saliency and morphological building index (MBI) extracted on difference images are used to generate a pseudo training set. Ultimately, object-based semi-supervised classification is implemented on this training set by applying random forest (RF). Most of the important changes are detected by the proposed method in our experiments. This study was checked for effectiveness using visual evaluation and numerical evaluation.

  8. Dynamics and Control of High-Rise Buildings under Multidirectional Wind Loads

    Directory of Open Access Journals (Sweden)

    Aly Mousaad Aly

    2011-01-01

    Full Text Available This paper presents a procedure for the response prediction and reduction in high-rise buildings under multidirectional wind loads. The procedure is applied to a very slender tall building that is instructive. The structure is exposed to both cross-wind and along-wind loads obtained from pressure measurements on a rigid model (scaled 1 : 100 that was tested in a wind tunnel with two different configurations of the surroundings. In the theoretical formulation, dynamic equations of the structure are introduced by finite element and 3D lumped mass modeling. The lateral responses of the building in the two directions are controlled at the same time using tuned mass dampers (TMDs and active tuned mass dampers (ATMDs commanded by LQR and fuzzy logic controllers, while the effects of the uncontrolled torsional response of the structure are simultaneously considered. Besides their simplicity, fuzzy logic controllers showed similar trend as LQR controllers under multidirectional wind loads. Nevertheless, the procedure presented in this study can help decision makers, involved in the design process, to choose among innovative solutions like structural control, different damping techniques, modifying geometry, or even changing materials.

  9. Damage extraction of buildings in the 2015 Gorkha, Nepal earthquake from high-resolution SAR data

    Science.gov (United States)

    Yamazaki, Fumio; Bahri, Rendy; Liu, Wen; Sasagawa, Tadashi

    2016-05-01

    Satellite remote sensing is recognized as one of the effective tools for detecting and monitoring affected areas due to natural disasters. Since SAR sensors can capture images not only at daytime but also at nighttime and under cloud-cover conditions, they are especially useful at an emergency response period. In this study, multi-temporal high-resolution TerraSAR-X images were used for damage inspection of the Kathmandu area, which was severely affected by the April 25, 2015 Gorkha Earthquake. The SAR images obtained before and after the earthquake were utilized for calculating the difference and correlation coefficient of backscatter. The affected areas were identified by high values of the absolute difference and low values of the correlation coefficient. The post-event high-resolution optical satellite images were employed as ground truth data to verify our results. Although it was difficult to estimate the damage levels for individual buildings, the high resolution SAR images could illustrate their capability in detecting collapsed buildings at emergency response times.

  10. Automated metric characterization of urban structure using building decomposition from very high resolution imagery

    Science.gov (United States)

    Heinzel, Johannes; Kemper, Thomas

    2015-03-01

    Classification approaches for urban areas are mostly of qualitative and semantic nature. They produce interpreted classes similar to those from land cover and land use classifications. As a complement to those classes, quantitative measures directly derived from the image could lead to a metric characterization of the urban area. While these metrics lack of qualitative interpretation they are able to provide objective measure of the urban structures. Such quantitative measures are especially important in rapidly growing cities since, beside of the growth in area, they can provide structural information for specific areas and detect changes. Rustenburg, which serves as test area for the present study, is amongst the fastest growing cities in South Africa. It reveals a heterogeneous face of housing and building structures reflecting social and/or economic differences often linked to the spatial distribution of industrial and local mining sites. Up to date coverage with aerial photographs is provided by aerial surveys in regular intervals. Also recent satellite systems provide imagery with suitable resolution. Using such set of very high resolution images a fully automated algorithm has been developed which outputs metric classes by systematically combining important measures of building structure. The measurements are gained by decomposition of buildings directly from the imagery and by using methods from mathematical morphology. The decomposed building objects serve as basis for the computation of grid statistics. Finally a systematic combination of the single features leads to combined metrical classes. For the dominant urban structures verification results indicate an overall accuracy of at least 80% on the single feature level and 70% for the combined classes.

  11. Federal R&D Agenda for Net Zero Energy, High-Performance Green Buildings

    Science.gov (United States)

    2008-09-30

    indicate a gap between design intent and construction that results in reduced energy performance (Torcellini et al. 2006). Building energy efficiency is...occupant, building, or community needs and preferences. New technologies that maximize building energy efficiency and minimize operational energy use...including low-income home energy assistance program, weatherization assistance, state energy programs, state building energy efficiency codes incentives and

  12. Design and Optimization of Slot Aluminum Alloy Connectors of Photovoltaics Applied to High-rise Building Facades

    Science.gov (United States)

    Liang, Ya-Wei; Zhang, Hong-Mei; Dong, Jin-Zhi; Shi, Zhen-Hua

    2016-05-01

    Building Integrated Photovoltaic (BIPV) is a resort to save energy and reduce heat gain of buildings, utilize new and renewable energy, solve environment problems and alleviate electricity shortage in large cities. The area needed to generate power makes facade integrated photovoltaic panel a superb choice, especially in high-rise buildings. Numerous scholars have hitherto explored Building Facade Integrated Photovoltaic, however, focusing mainly on thermal performance, which fails to ensure seismic safety of high-rise buildings integrated photovoltaic. Based on connecting forms of the glass curtain wall, a connector jointing photovoltaic panel and facade was designed, which underwent loading position and size optimization. Static loading scenarios were conducted to test and verify the connector's mechanical properties under gravity and wind loading by means of HyperWorks. Compared to the unoptimized design, the optimized one saved material and managed to reduce maximum deflection by 74.64%.

  13. Proceedings of the 6. International Conference on Multipurpose High-rise Towers and Tall Buildings. CD-ROM ed.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This conference provided an opportunity to exchange information on recent building and construction research with particular reference to high-rise towers and tall buildings. The main issues were arranged into two sessions dealing with innovative new designs for tall structures and designs for fire safety. The presentations evaluated best practices in construction with reference to a wide range of topics, including serviceability considerations for tall residential buildings; super tall housing architectural and socio-psychological implications; design of drainage systems for high-rise buildings; bionic towers and vertical gardens; early warning and response measures for buildings at risk to chemical and biological threats; earthquake protection; safety measures for people with disabilities; and, fire resistance. The conference featured 10 presentations, of which 1 has been indexed separately for inclusion in this database. refs., tabs., figs.

  14. The Airborne Transmission of Infection Between Flats in High-rise Residential Buildings

    DEFF Research Database (Denmark)

    Gao, N. P.; Niu, J. L.; Perino, M.

    2009-01-01

    Several case clusters occurred in high-rise residential buildings in Hong Kong in the 2003 SARS (the severe acute respiratory syndrome) epidemic, which motivated a series of engineering investigations into the possible airborne transport routes. It is suspected that, driven by buoyancy force......, the polluted air that exits the window of the lower floor may re-enter the immediate upper floor through the window on the same side. This cascade effect has been quantified and reported in a previous paper, and it is found that, by tracer gas concentration analysis, the room in the adjacent upstairs may...

  15. Reliability of system identification technique in super high-rise building

    Directory of Open Access Journals (Sweden)

    Ayumi eIkeda

    2015-07-01

    Full Text Available A smart physical-parameter based system identification method has been proposed in the previous paper. This method deals with time-variant nonparametric identification of natural frequencies and modal damping ratios using ARX (Auto-Regressive eXogenous models and has been applied to high-rise buildings during the 2011 off the Pacific coast of Tohoku earthquake. In this perspective article, the current state of knowledge in this class of system identification methods is explained briefly and the reliability of this smart method is discussed through the comparison with the result by a more confident technique.

  16. InGaN micro-LED-pillar as the building block for high brightness emitters

    KAUST Repository

    Shen, Chao

    2013-01-01

    In summary, we confirmed the improved electrical and optical characteristics, with reduced efficiency droop in InGaN μLED-pillars when these devices were scaled down in size. We demonstrated that strain relief contributed to further improvement in EQE characteristics in small InGaN μLED-pillars (D < 50 μm), apart from the current spreading effect. The μLED-pillar can be deployed as the building block for large effective-area, high brightness emitter. © 2013 IEEE.

  17. Cavity-enhanced room-temperature high sensitivity optical Faraday magnetometry

    Science.gov (United States)

    Sun, Hui; Lei, Yaohua; Fan, Shuangli; Zhang, Qiaolin; Guo, Hong

    2017-01-01

    We propose a cavity QED system with two-photon Doppler-free configuration for weak magnetic field detection with high sensitivity at room temperature based on cavity electromagnetically induced transparency. Owing to the destructive interference induced by the control and driving fields, two transparency channels are opened. The Faraday rotation within two transparency channels can be used to detect weak magnetic field with high sensitivity at room temperature. The sensitivity with single photon and multiphoton probe inputs is analyzed. With single photon measurement, our numerical calculations demonstrate that the sensitivity with 3.8nT/√{Hz} and 6.4nT/√{Hz} could be achieved. When we measure the magnetic field with multiphoton input, the sensitivity can be improved to 7.7fT/√{Hz} and 25.6fT/√{Hz} under the realistic experimental conditions.

  18. High-throughput, Highly Sensitive Analyses of Bacterial Morphogenesis Using Ultra Performance Liquid Chromatography.

    Science.gov (United States)

    Desmarais, Samantha M; Tropini, Carolina; Miguel, Amanda; Cava, Felipe; Monds, Russell D; de Pedro, Miguel A; Huang, Kerwyn Casey

    2015-12-25

    The bacterial cell wall is a network of glycan strands cross-linked by short peptides (peptidoglycan); it is responsible for the mechanical integrity of the cell and shape determination. Liquid chromatography can be used to measure the abundance of the muropeptide subunits composing the cell wall. Characteristics such as the degree of cross-linking and average glycan strand length are known to vary across species. However, a systematic comparison among strains of a given species has yet to be undertaken, making it difficult to assess the origins of variability in peptidoglycan composition. We present a protocol for muropeptide analysis using ultra performance liquid chromatography (UPLC) and demonstrate that UPLC achieves resolution comparable with that of HPLC while requiring orders of magnitude less injection volume and a fraction of the elution time. We also developed a software platform to automate the identification and quantification of chromatographic peaks, which we demonstrate has improved accuracy relative to other software. This combined experimental and computational methodology revealed that peptidoglycan composition was approximately maintained across strains from three Gram-negative species despite taxonomical and morphological differences. Peptidoglycan composition and density were maintained after we systematically altered cell size in Escherichia coli using the antibiotic A22, indicating that cell shape is largely decoupled from the biochemistry of peptidoglycan synthesis. High-throughput, sensitive UPLC combined with our automated software for chromatographic analysis will accelerate the discovery of peptidoglycan composition and the molecular mechanisms of cell wall structure determination.

  19. A highly sensitive method for the detection of Chrysanthemum virus B

    Directory of Open Access Journals (Sweden)

    Zhiyong Guan

    2017-03-01

    Conclusion: A highly specific and sensitive nested PCR-based assay has been described for detecting CVB. This new method is highly specific and sensitive for the detection of CVB, which is known to infect chrysanthemum plants in the fields. Further, this protocol has an advantage over traditional methods as it is more cost-effective. This assay is ideal for an early stage diagnosis of the disease.

  20. Integration of a High Sensitivity MEMS Directional Sound Sensor With Readout Electronics

    Science.gov (United States)

    2012-12-01

    ERİŞMİŞ, “ MEMS accelerometers and gyroscopes for inertial measurement units,” M.S. thesis, Middle East Technical University, Cankaya, Ankara, Turkey...HIGH SENSITIVITY MEMS DIRECTIONAL SOUND SENSOR WITH READOUT ELECTRONICS by John D. Roth December 2012 Thesis Advisor: Gamani Karunasiri...3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Integration of a High Sensitivity MEMS Directional Sound Sensor with

  1. High-sensitivity Cardiac Troponin Elevation after Electroconvulsive Therapy: A Prospective, Observational Cohort Study.

    Science.gov (United States)

    Duma, Andreas; Pal, Swatilika; Johnston, Joshua; Helwani, Mohammad A; Bhat, Adithya; Gill, Bali; Rosenkvist, Jessica; Cartmill, Christopher; Brown, Frank; Miller, J Philip; Scott, Mitchell G; Sanchez-Conde, Francisco; Jarvis, Michael; Farber, Nuri B; Zorumski, Charles F; Conway, Charles; Nagele, Peter

    2017-04-01

    While electroconvulsive therapy is widely regarded as a lifesaving and safe procedure, evidence regarding its effects on myocardial cell injury is sparse. The objective of this investigation was to determine the incidence and magnitude of new cardiac troponin elevation after electroconvulsive therapy using a novel high-sensitivity cardiac troponin I assay. This was a prospective cohort study in adult patients undergoing electroconvulsive therapy in a single academic center (up to three electroconvulsive therapy treatments per patient). The primary outcome was new high-sensitivity cardiac troponin I elevation after electroconvulsive therapy, defined as an increase of high-sensitivity cardiac troponin I greater than 100% after electroconvulsive therapy compared to baseline with at least one value above the limit of quantification (10 ng/l). Twelve-lead electrocardiogram and high-sensitivity cardiac troponin I values were obtained before and 15 to 30 min after electroconvulsive therapy; in a subset of patients, an additional 2-h high-sensitivity cardiac troponin I value was obtained. The final study population was 100 patients and a total of 245 electroconvulsive therapy treatment sessions. Eight patients (8 of 100; 8%) experienced new high-sensitivity cardiac troponin I elevation after electroconvulsive therapy with a cumulative incidence of 3.7% (9 of 245 treatments; one patient had two high-sensitivity cardiac troponin I elevations), two of whom had a non-ST-elevation myocardial infarction (incidence 2 of 245; 0.8%). Median high-sensitivity cardiac troponin I concentrations did not increase significantly after electroconvulsive therapy. Tachycardia and/or elevated systolic blood pressure developed after approximately two thirds of electroconvulsive therapy treatments. Electroconvulsive therapy appears safe from a cardiac standpoint in a large majority of patients. A small subset of patients with preexisting cardiovascular risk factors, however, may develop new

  2. Making sense of high sensitivity troponin assays and their role in clinical care.

    Science.gov (United States)

    Daniels, Lori B

    2014-04-01

    Cardiac troponin assays have an established and undisputed role in the diagnosis and risk stratification of patients with acute myocardial infarction. As troponin assays gets more sensitive and more precise, the number of potential uses has rapidly expanded, but the use of this test has also become more complicated and controversial. Highly sensitive troponin assays can now detect troponin levels in most individuals, but accurate interpretation of these levels requires a clear understanding of the assay in the context of the clinical scenario. This paper provides a practical and up-to-date overview of the uses of highly sensitive troponin assays for diagnosis, prognosis, and risk stratification in clinical practice.

  3. High sensitivity probe absorption technique for time-of-flight measurements on cold atoms

    Indian Academy of Sciences (India)

    A K Mohapatra; C S Unnikrishnan

    2006-06-01

    We report on a phase-sensitive probe absorption technique with high sensitivity, capable of detecting a few hundred ultra-cold atoms in flight in an observation time of a few milliseconds. The large signal-to-noise ratio achieved is sufficient for reliable measurements on low intensity beams of cold atoms. We demonstrate the high sensitivity and figure of merit of the simple method by measuring the time-of-flight of atoms moving upwards from a magneto-optical trap released in the gravitational field.

  4. High-overtone Bulk-Acoustic Resonator gravimetric sensitivity: towards wideband acoustic spectroscopy

    CERN Document Server

    Rabus, D; Ballandras, S; Baron, T; Lebrasseur, E; Carry, E

    2015-01-01

    In the context of direct detection sensors with compact dimensions, we investigate the gravimetric sensitivity of High-overtone Bulk Acoustic Resonators, through modeling of their acoustic characteristics and experiment. The high frequency characterizing such devices is expected to induce a significant effect when the acoustic field boundary conditions are modified by a thin adlayer. Furthermore, the multimode spectral characteristics is considered for wideband acoustic spectroscopy of the adlayer, once the gravimetric sensitivity dependence of the various overtones is established. Finally, means of improving the gravimetric sensitivity by confining the acoustic field in a low acoustic-impedance layer is theoretically established.

  5. TEST CELLS SE-5 - SE-8 - SE-10 IN THE ENGINE RESEARCH BUILDING ERB AND 117 HIGH ENERGY FUELS LABORAT

    Science.gov (United States)

    1963-01-01

    TEST CELLS SE-5 - SE-8 - SE-10 IN THE ENGINE RESEARCH BUILDING ERB AND 117 HIGH ENERGY FUELS LABORATORY HEFL - TRANSDUCER INSTRUMENTATION CONSOLE SE-10 - TEMPERATURE INSTRUMENTATION CONSOLE SE-10 - MODULE FUEL CELL EXPERIMENT SE-8 -

  6. Lessons Learned from Case Studies of Six High-Performance Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Torcellini, P.; Pless, S.; Deru, M.; Griffith, B.; Long, N.; Judkoff, R.

    2006-06-01

    Commercial buildings have a significant impact on energy use and the environment. They account for approximately 18% (17.9 quads) of the total primary energy consumption in the United States (DOE 2005). The energy used by the building sector continues to increase, primarily because new buildings are added to the national building stock faster than old buildings are retired. Energy consumption by commercial buildings will continue to increase until buildings can be designed to produce more energy than they consume. As a result, the U.S. Department of Energy's (DOE) Building Technologies Program has established a goal to create the technology and knowledge base for marketable zero-energy commercial buildings (ZEBs) by 2025.

  7. High strain rate sensitivity of hardness in quinary Ti-Zr-Hf-Cu-Ni high entropy metallic glass thin films

    Science.gov (United States)

    Zhao, Shaofan; Wang, Haibin; Xiao, Lin; Guo, Nan; Zhao, Delin; Yao, Kefu; Chen, Na

    2017-10-01

    Quinary Ti-Zr-Hf-Cu-Ni high-entropy metallic glass thin films were produced by magnetron sputter deposition. Nanoindentation tests indicate that the deposited film exhibits a relatively large hardness of 10.4±0.6 GPa and a high elastic modulus of 131±11 GPa under the strain rate of 0.5 s-1. Specifically, the strain rate sensitivity of hardness measured for the thin film is 0.05, the highest value reported for metallic glasses so far. Such high strain rate sensitivity of hardness is likely due to the high-entropy effect which stabilizes the amorphous structure with enhanced homogeneity.

  8. Materials development and field demonstration of high-recycled-content concrete for energy-efficient building construction

    Energy Technology Data Exchange (ETDEWEB)

    Ostowari, Ken; Nosson, Ali

    2000-09-30

    The project developed high-recycled-content concrete material with balanced structural and thermal attributes for use in energy-efficient building construction. Recycled plastics, tire, wool, steel and concrete were used as replacement for coarse aggregates in concrete and masonry production. With recycled materials the specific heat and thermal conductivity of concrete could be tailored to enhance the energy-efficiency of concrete buildings. A comprehensive field project was implemented which confirmed the benefits of high-recycled-content concrete for energy-efficient building construction.

  9. The 2009 Space Science Component of UNH Project SMART and High School Students Building a High-Altitude Balloon Payload

    Science.gov (United States)

    Smith, C. W.; Broad, L.; Chen, L.; Farrugia, C. J.; Frederick-Frost, K.; Goelzer, S.; Kucharek, H.; Messeder, R.; Moebius, E.; Puhl-Quinn, P. A.; Torbert, R. B.

    2009-12-01

    For the past 19 years the University of New Hampshire has offered a unique research and education opportunity to motivated high-school students called Project SMART (Science and Mathematics Achievement through Research Training). The Space Science module is strongly research based. Students work in teams of two on real research projects carved from the research programs of the faculty. The projects are carefully chosen to match the abilities of the students. The students receive classes in basic physics as well as lectures in space science to help them with their work. This year the research included the analysis of magnetic reconnection observations and Crater FTE observation, both by the CLUSTER spacecraft, the building of Faraday cups for thermal ion measurements in our thermal vacuum facility, and analysis of the IBEX star sensor. In addition to this, the students work on one combined project and for the past several years this project has been the building of a payload for a high-altitude balloon. The students learn to integrate telemetry and GPS location hardware while they build several small experiments that they then fly to the upper reaches of the Earth's atmosphere. This year the payload included a small video camera and the payload flew to 96,000 feet, capturing images of weather patterns as well as the curvature of the Earth, thickness of the atmosphere, and black space. In addition to still photos, we will be showing 2- and 7-minute versions of the 90-minute flight video that include footage from peak altitude, the bursting of the balloon, and initial descent.

  10. Expanded organic building units for the construction of highly porous metal-organic frameworks.

    Science.gov (United States)

    Kong, Guo-Qiang; Han, Zhi-Da; He, Yabing; Ou, Sha; Zhou, Wei; Yildirim, Taner; Krishna, Rajamani; Zou, Chao; Chen, Banglin; Wu, Chuan-De

    2013-10-25

    Two new organic building units that contain dicarboxylate sites for their self-assembly with paddlewheel [Cu2(CO2)4] units have been successfully developed to construct two isoreticular porous metal-organic frameworks (MOFs), ZJU-35 and ZJU-36, which have the same tbo topologies (Reticular Chemistry Structure Resource (RCSR) symbol) as HKUST-1. Because the organic linkers in ZJU-35 and ZJU-36 are systematically enlarged, the pores in these two new porous MOFs vary from 10.8 Å in HKUST-1 to 14.4 Å in ZJU-35 and 16.5 Å in ZJU-36, thus leading to their higher porosities with Brunauer-Emmett-Teller (BET) surface areas of 2899 and 4014 m(2) g(-1) for ZJU-35 and ZJU-36, respectively. High-pressure gas-sorption isotherms indicate that both ZJU-35 and ZJU-36 can take up large amounts of CH4 and CO2, and are among the few porous MOFs with the highest volumetric storage of CH4 under 60 bar and CO2 under 30 bar at room temperature. Their potential for high-pressure swing adsorption (PSA) hydrogen purification was also preliminarily examined and compared with several reported MOFs, thus indicating the potential of ZJU-35 and ZJU-36 for this important application. Studies show that most of the highly porous MOFs that can volumetrically take up the greatest amount of CH4 under 60 bar and CO2 under 30 bar at room temperature are those self-assembled from organic tetra- and hexacarboxylates that contain m-benzenedicarboxylate units with the [Cu2(CO2)4] units, because this series of MOFs can have balanced porosities, suitable pores, and framework densities to optimize their volumetric gas storage. The realization of the two new organic building units for their construction of highly porous MOFs through their self-assembly with [Cu2(CO2)4] units has provided great promise for the exploration of a large number of new tetra- and hexacarboxylate organic linkers based on these new organic building units in which different aromatic backbones can be readily incorporated

  11. Highly Sensitive Local Surface Plasmon Resonance in Anisotropic Au Nanoparticles Deposited on Nanofibers

    Directory of Open Access Journals (Sweden)

    Masanari Saigusa

    2015-01-01

    Full Text Available This paper reports the facile and high-throughput fabrication method of anisotropic Au nanoparticles with a highly sensitive local surface plasmon resonance (LPR using cylindrical nanofibers as substrates. The substrates consisting of nanofibers were prepared by the electrospinning of poly(vinylidene fluoride (PVDF. The Au nanoparticles were deposited on the surface of electrospun nanofibers by vacuum evaporation. Scanning electron microscopy revealed the formation of a curved Au island structure on the surface of cylindrical nanofibers. Polarized UV-visible extinction spectroscopy showed anisotropy in their LPR arising from the high surface curvature of the nanofiber. The LPR of the Au nanoparticles on the thinnest nanofiber with a diameter of ~100 nm showed maximum refractive index (RI sensitivity over 500 nm/RI unit (RIU. The close correlation between the fiber diameter dependence of the RI sensitivity and polarization dependence of the LPR suggests that anisotropic Au nanoparticles improve RI sensitivity.

  12. Fano resonance-based highly sensitive, compact temperature sensor on thin film lithium niobate.

    Science.gov (United States)

    Qiu, Wentao; Ndao, Abdoulaye; Vila, Venancio Calero; Salut, Roland; Courjal, Nadège; Baida, Fadi Issam; Bernal, Maria-Pilar

    2016-03-15

    In this Letter, we report a Fano resonance-based highly sensitive and compact temperature sensor fabricated on thin film lithium niobate (TFLN) Suzuki phase lattice (SPL) photonic crystal. The experimental sensitivity is estimated to be 0.77 nm/°C with a photonic crystal size of only 25  μm × 24  μm. This sensitivity is 38 times larger than the intrinsic one of lithium niobate which is 0.02 nm/°C. The demonstrated sharp and high extinction ratio characteristics of the Fano lineshape resonance could be an excellent candidate in developing a high sensitivity temperature sensor, electric field sensor, etc.

  13. Bionic Optimisation of the Earthquake Resistance of High Buildings by Tuned Mass Dampers

    Institute of Scientific and Technical Information of China (English)

    Rolf Steinbuch

    2011-01-01

    The optimisation of earthquake resistance of high buildings by multi-tuned mass dampers was investigated using bionic algorithms. In bionic or evolutionary optimisation studies the properties of parents are crossed and mutated to produce a new generation with slightly different properties. The kids which best satisfy the object of the study, become the parents of the next generation. After a series of generations essential improvements of the object may be observed. Tuned mass dampers are widely used to reduce the impact of dynamic excitations on structures. A single mass system and multi-mass oscillators help to explain the mechanics of the dampers. To apply the bionic optimisation strategy to high buildings with passive tuned mass dampers subject to seismic loading a special beam element has been developed. In addition to the 6 degrees of freedom of a conventional beam element, it has 2 degrees of freedom for the displacements of the dampers. It allows for fast studies of many variants. As central result, efficient designs for damping systems along the height of an edifice are found. The impact on the structure may be reduced essentially by the use of such dampers designed to interact in an optimal way.

  14. Combined liver and kidney transplantation in a highly sensitized and positively cross-matched patient

    Directory of Open Access Journals (Sweden)

    Salem Alqurashi

    2011-01-01

    Full Text Available Combined liver kidney transplantation (CLKT has been used on many occasions and proved to be a successful event for both liver and kidney in highly sensitized patients. Our aim was to review the immunological and other laboratory results of a CLKT in a highly sensitized patient. CLKT was used to treat a highly sensitized, 42-year-old female. She was suffering from end-stage liver disease due to hepatitis C virus (HCV infection and renal disease due to diabetic nephropathy. Cross-matching, panel reactive assay (PRA and routine laboratory tests for liver and renal function were carried out before and after the CLKT. Prior to the CLKT, the patient was highly sensitized with human leukocytes antigens (anti-HLA class I antibodies (>90%. Patient was offered CLKT from a deceased donor. She had donor-specific antibodies, class I and II. Both T and B CDC cross-matches (XM were positive pre-transplant and eight hours post-transplant. Both cross-match and PRA results became completely negative six days post CKLT. Almost 30 months post CLKT, her renal function is normal and negative for class I and II PRA. Liver graft appears to be protective for renal graft when they are combined even in highly sensitized patients. CLKT is very useful in overcoming sensitization in addition to treating end-stage liver and renal diseases.

  15. Interpersonal sensitivity and functioning impairment in youth at ultra-high risk for psychosis.

    Science.gov (United States)

    Masillo, A; Valmaggia, L R; Saba, R; Brandizzi, M; Lindau, J F; Solfanelli, A; Curto, M; Narilli, F; Telesforo, L; Kotzalidis, G D; Di Pietro, D; D'Alema, M; Girardi, P; Fiori Nastro, P

    2016-01-01

    A personality trait that often elicits poor and uneasy interpersonal relationships is interpersonal sensitivity. The aim of the present study was to explore the relationship between interpersonal sensitivity and psychosocial functioning in individuals at ultra-high risk for psychosis as compared to help-seeking individuals who screened negative for an ultra-high risk of psychosis. A total sample of 147 adolescents and young adult who were help seeking for emerging mental health problems participated in the study. The sample was divided into two groups: 39 individuals who met criteria for an ultra-high-risk mental state (UHR), and 108 (NS). The whole sample completed the Interpersonal Sensitivity Measure (IPSM) and the Global Functioning: Social and Role Scale (GF:SS; GF:RS). Mediation analysis was used to explore whether attenuated negative symptoms mediated the relationship between interpersonal sensitivity and social functioning. Individuals with UHR state showed higher IPSM scores and lower GF:SS and GF:RS scores than NS participants. A statistically negative significant correlation between two IPSM subscales (Interpersonal Awareness and Timidity) and GF:SS was found in both groups. Our results also suggest that the relationship between the aforementioned aspects of interpersonal sensitivity and social functioning was not mediated by negative prodromal symptoms. This study suggests that some aspects of interpersonal sensitivity were associated with low level of social functioning. Assessing and treating interpersonal sensitivity may be a promising therapeutic target to improve social functioning in young help-seeking individuals.

  16. Nearly Zero Energy Standard for Non-Residential Buildings with high Energy Demands—An Empirical Case Study Using the State-Related Properties of BAVARIA

    Directory of Open Access Journals (Sweden)

    Michael Keltsch

    2017-03-01

    Full Text Available The Energy Performance of Buildings Directive (EPBD 2010 calls for the Nearly Zero Energy Building (nZEB Standard for new buildings from 2021 onwards: Buildings using “almost no energy” are powered by renewable sources or by the energy produced by the building itself. For residential buildings, this ambitious new standard has already been reached. But for other building types, this goal is still far away. The potential of these buildings to meet a nZEB Standard was investigated by analyzing ten case studies, representing non-residential buildings with different uses. The analysis shows that the primary characteristics common to critical building types are a dense building context with a very high degree of technical installation (such as hospital, research, and laboratory buildings. The large primary energy demand of these types of buildings cannot be compensated by building- and property-related energy generation, including off-site renewables. If the future nZEB Standard were to be defined with lower requirements because of this, the state-related properties of Bavaria suggest that the real potential energy savings available in at least 85% of all new buildings would be insufficiently exploited. Therefore, it would be more useful to individualize the legal energy verification process for new buildings, to distinguish critical building types such as laboratories and hospitals from the other building types.

  17. Energy and financial performance of micro-CHP in connection with high performance buildings

    Energy Technology Data Exchange (ETDEWEB)

    Sicre, B.; Buhring, A. [Fraunhofer Inst. fur Solare Energiesysteme, Freiburg (Germany); Platzer, B. [Chemnitz Technische Univ., Chemnitz (Germany). Fakultat fur Maschinenbau

    2005-07-01

    Micro-Combined Heating and Power plant (mCHP) installations in high performance houses were discussed in relation to energy conservation and cost savings. The effective exploitation of thermal output is crucial to achieving high levels of efficiency in mCHP systems, as they have a limited electrical conversion efficiency. However, high-performance residential buildings have a heat-to-power load ratio that is not well suited to the load ratios of mCHP systems. The results of an annual simulation confirmed that current performance of mCHP systems is not high enough to make them viable with standard high-performance energy converters. It was suggested that integrating a mCHP system into a heating, ventilation and air conditioning (HVAC) system may increase its efficiency. Several integration concepts were described in this paper, and assessed by simulation. A controller model capable of matching the cogeneration system output to electrical demand, thermal demand, economic and environmental criteria was developed and implemented. Three control modes were designed in order to modulate the output power of the plant. The regulating variables were the natural gas mass flow rates and the current density in the Solid Oxide Fuel Cell (SOFC) stack. SOFC performance data in terms of electrical and thermal efficiency versus fuel input and current density were provided to the controller in the form of fitting curves. The prediction of household electricity consumption was derived from the previous time step value provided by a metering system. A passive house construction was used for the building model. Domestic hot water and electricity profiles were presented, as well as details of space heating. The financial viability of the the mCHP system was also discussed. A preliminary simulation of an HVAC system was presented using a modular simulation environment. Results of the boiler and compact dwelling SOFC ventilation system were presented. It was concluded that an integrated

  18. Design and Build of an Electrical Machines’ High Speed Measurement System at Low Cost

    Directory of Open Access Journals (Sweden)

    Constantinos C. Kontogiannis

    2014-01-01

    Full Text Available The principal objective of this paper is to demonstrate the capability of high speed measurement and acquisition equipment design and build in the laboratory at a very low cost. The presented architecture employees highly integrated market components eliminating thus the complexity of the hardware and software stack. The key element of the proposed system is a Hi-Speed USB to Serial/FIFO development module that is provided with full software and driver support for most popular operating systems. This module takes over every single task needed to get the data from the A/D to the user software gluelessly and transparently, solving this way the most difficult problem in data acquisition systems which is the fast and reliable communication with a host computer. Other ideas tested and included in this document offer Hall Effect measuring solutions using some excellent features and very low cost ICs widely available on the market today.

  19. Proposed helmet PET geometries with add-on detectors for high sensitivity brain imaging

    Science.gov (United States)

    Tashima, Hideaki; Yamaya, Taiga

    2016-10-01

    For dedicated brain PET, we can significantly improve sensitivity for the cerebrum region by arranging detectors in a compact hemisphere. The geometrical sensitivity for the top region of the hemisphere is increased compared with conventional cylindrical PET consisting of the same number of detectors. However, the geometrical sensitivity at the center region of the hemisphere is still low because the bottom edge of the field-of-view is open, the same as for the cylindrical PET. In this paper, we proposed a helmet PET with add-on detectors for high sensitivity brain PET imaging for both center and top regions. The key point is the add-on detectors covering some portion of the spherical surface in addition to the hemisphere. As the location of the add-on detectors, we proposed three choices: a chin detector, ear detectors, and a neck detector. For example, the geometrical sensitivity for the region-of-interest at the center was increased by 200% by adding the chin detector which increased the size by 12% of the size of the hemisphere detector. The other add-on detectors gave almost the same increased sensitivity effect as the chin detector did. Compared with standard whole-body-cylindrical PET, the proposed geometries can achieve 2.6 times higher sensitivity for brain region even with less than 1/4 detectors. In addition, we conducted imaging simulations for geometries with a diameter of 250 mm and with high resolution depth-of-interaction detectors. The simulation results showed that the proposed geometries increased image quality, and all of the add-on detectors were equivalently effective. In conclusion, the proposed geometries have high potential for widespread applications in high-sensitivity, high-resolution, and low-cost brain PET imaging.

  20. High-sensitivity and high-Q-factor glass photonic crystal cavity and its applications as sensors.

    Science.gov (United States)

    Siraji, Ashfaqul Anwar; Zhao, Yang

    2015-04-01

    We investigate the properties of a planar photonic crystal cavity on glass and its applications as sensors. An airbridged twofold defect cavity on Schott glass background and Gorilla glass substrate has been designed for high Q-factor up to 4459. The average sensitivity of the cavity resonance to background refractive index is 388 nm/Refractive Index Unit. The resonant wavelength is sensitive to background temperature by 18.5 pm/°C. The designed sensors show much higher sensitivity than those based on waveguide interferometers or photonic bandgap structures without cavity resonance. The results are also useful for experimental studies of glass photonic devices.

  1. Fully printed, highly sensitive multifunctional artificial electronic whisker arrays integrated with strain and temperature sensors.

    Science.gov (United States)

    Harada, Shingo; Honda, Wataru; Arie, Takayuki; Akita, Seiji; Takei, Kuniharu

    2014-04-22

    Mammalian-mimicking functional electrical devices have tremendous potential in robotics, wearable and health monitoring systems, and human interfaces. The keys to achieve these devices are (1) highly sensitive sensors, (2) economically fabricated macroscale devices on flexible substrates, and (3) multifunctions beyond mammalian functions. Although highly sensitive artificial electronic devices have been reported, none have been fabricated using cost-effective macroscale printing methods and demonstrate multifunctionalities of artificial electronics. Herein we report fully printed high-sensitivity multifunctional artificial electronic whiskers (e-whisker) integrated with strain and temperature sensors using printable nanocomposite inks. Importantly, changing the composition ratio tunes the sensitivity of strain. Additionally, the printed temperature sensor array can be incorporated with the strain sensor array beyond mammalian whisker functionalities. The sensitivity for the strain sensor is impressively high (∼59%/Pa), which is the best sensitivity reported to date (>7× improvement). As the proof-of-concept for a truly printable multifunctional artificial e-whisker array, two- and three-dimensional space and temperature distribution mapping are demonstrated. This fully printable flexible sensor array should be applicable to a wide range of low-cost macroscale electrical applications.

  2. Longevity Tests of High-Sensitivity BD-PND Bubble Dosimeters

    Energy Technology Data Exchange (ETDEWEB)

    Radev, R; Carlberg, E

    2002-07-09

    Medium- and very-high-sensitivity neutron bubble dosimeters (BD-PNDs) made by Bubble Technology Industries (BTI) were used to study the life span of such dosimeters in a standard setup with a {sup 252}Cf source. Although data on the longevity of bubble dosimeters with low and medium sensitivity exist, such data for dosimeters with high and very high sensitivity are not readily available. The manufacturer guarantees optimum dosimeter performance for 3 months after receipt. However, it is important to know the change in the dosimeters' characteristics with time, especially after the first 3 months. The long-term performance of four sets of very high sensitivity and one set of medium-sensitivity bubble dosimeters was examined for periods of up to 13 months. During that time, the detectors were exposed and reset more than 20 times. Although departures from initial detection sensitivity were observed in several cases, the detectors indicated a significantly longer life span than stated in the manufacturer's warranty. In addition, the change in the number of bubbles and in evaluated neutron dose as a function of the time from the end of exposure until the dosimeters were read was investigated.

  3. Is sensitivity to reward associated with the malleability of implicit inclinations toward high-fat food?

    Science.gov (United States)

    Ashby, Casey R; Stritzke, Werner G K

    2013-08-01

    Two experiments examined the effect of positive and negative priming on implicit approach and avoidance inclinations toward high-fat food stimuli in participants high or low in reward sensitivity, using personalized unipolar variants of the Implicit Association Test (IAT; A. G. Greenwald, D. E. McGhee, & J. L. K. Schwartz, 1998, "Measuring individual differences in implicit cognition: The Implicit Association Test," Journal of Personality and Social Psychology, Vol. 74, pp. 1464-1480). Participants high in reward sensitivity showed an automatic processing bias that is characterized by a dual vulnerability of being particularly susceptible to priming of the rewarding aspects of high-fat foods, while being unaffected by priming of the negative aspects of those foods. In contrast, participants low in reward sensitivity generally showed no facilitation of implicit-approach inclinations following positive priming, but consistently showed facilitation of implicit-avoidance inclinations following negative priming. These results are consistent with the revised reinforcement sensitivity theory ( J. A. Gray & N. McNaughton, 2000, The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system, 2nd ed., New York, NY, Oxford University Press.) and suggest that the systems mediating reward sensitivity and punishment sensitivity are not orthogonal, as predicted by the separable subsystems hypothesis, but can be interdependent, as predicted by the joint subsystems hypothesis.

  4. High maltose sensitivity of sweet taste receptors in the Japanese macaque (Macaca fuscata)

    Science.gov (United States)

    Nishi, Emiko; Tsutsui, Kei; Imai, Hiroo

    2016-01-01

    Taste sensitivity differs among animal species depending on feeding habitat. To humans, sucrose is one of the sweetest natural sugars, and this trait is expected to be similar in other primates. However, previous behavioral tests have shown that some primate species have equal preferences for maltose and sucrose. Because sweet tastes are recognized when compounds bind to the sweet taste receptor Tas1R2/Tas1R3, we evaluated the responses of human and Japanese macaque Tas1R2/Tas1R3 to various natural sugars using a heterologous expression system. Human Tas1R2/Tas1R3 showed high sensitivity to sucrose, as expected; however, Japanese macaque Tas1R2/Tas1R3 showed equally high sensitivity to maltose and sucrose. Furthermore, Japanese macaques showed equally high sensitivity to sucrose and maltose in a two-bottle behavioral experiment. These results indicate that Japanese macaques have high sensitivity to maltose, and this sensitivity is directly related to Tas1R2/Tas1R3 function. This is the first molecular biological evidence that for some primate species, sucrose is not the most preferable natural sugar, as it is for humans. PMID:27982108

  5. A highly sensitive humidity sensor based on a nanofibrous membrane coated quartz crystal microbalance

    Energy Technology Data Exchange (ETDEWEB)

    Wang Xianfeng; Ding Bin [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620 (China); Yu Jianyong [Nanomaterials Research Center, Modern Textile Institute, Donghua University, Shanghai 200051 (China); Wang, Moran [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Pan Fukui, E-mail: binding@dhu.edu.cn [College of Textiles and Fashion, Qingdao University, Qingdao 266071 (China)

    2010-02-05

    A novel humidity sensor was fabricated by electrospinning deposition of nanofibrous polyelectrolyte membranes as sensitive coatings on a quartz crystal microbalance (QCM). The results of sensing experiments indicated that the response of the sensors increased by more than two orders of magnitude with increasing relative humidity (RH) from 6 to 95% at room temperature, exhibiting high sensitivity, and that, in the range of 20-95% RH, the Log({Delta}f) showed good linearity. The sensitivity of fibrous composite polyacrylic acid (PAA)/poly(vinyl alcohol) (PVA) membranes was two times higher than that of the corresponding flat films at 95% RH. Compared with fibrous PAA/PVA membranes, the nanofibrous PAA membranes exhibited remarkably enhanced humidity sensitivity due to their high PAA content and large specific surface area caused by the formation of ultrathin nanowebs among electrospun fibers. Additionally, the resultant sensors exhibited a good reversible behavior and good long term stability.

  6. A highly sensitive humidity sensor based on a nanofibrous membrane coated quartz crystal microbalance

    Science.gov (United States)

    Wang, Xianfeng; Ding, Bin; Yu, Jianyong; Wang, Moran; Pan, Fukui

    2010-02-01

    A novel humidity sensor was fabricated by electrospinning deposition of nanofibrous polyelectrolyte membranes as sensitive coatings on a quartz crystal microbalance (QCM). The results of sensing experiments indicated that the response of the sensors increased by more than two orders of magnitude with increasing relative humidity (RH) from 6 to 95% at room temperature, exhibiting high sensitivity, and that, in the range of 20-95% RH, the Log(Δf) showed good linearity. The sensitivity of fibrous composite polyacrylic acid (PAA)/poly(vinyl alcohol) (PVA) membranes was two times higher than that of the corresponding flat films at 95% RH. Compared with fibrous PAA/PVA membranes, the nanofibrous PAA membranes exhibited remarkably enhanced humidity sensitivity due to their high PAA content and large specific surface area caused by the formation of ultrathin nanowebs among electrospun fibers. Additionally, the resultant sensors exhibited a good reversible behavior and good long term stability.

  7. Building America Top Innovations 2012: Reduced Call-Backs with High-Performance Production Builders

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-01-01

    This Building America Top Innovations profile describes ways Building America teams have helped builders cut call-backs. Harvard University study found builders who worked with Building America had a 50% drop in call-backs. One builder reported a 50-fold reduction in the incidence of pipe freezing, a 50% reduction in drywall cracking, and a 60% decline in call-backs.

  8. High sensitivity to mass-ratio variation in deep molecular potentials

    CERN Document Server

    Hanneke, D; Lane, D A

    2016-01-01

    Molecular vibrational transitions are prime candidates for model-independent searches for variation of the proton-to-electron mass ratio. Searches for present-day variation achieve highest sensitivity with deep molecular potentials. We identify several high-sensitivity transitions in the deeply bound ${\\rm O}_2^+$ molecular ion. These transitions are electric-dipole forbidden and thus have narrow linewidths. The most sensitive transitions take advantage of an accidental degeneracy between vibrational states in different electronic potentials. We suggest experimentally feasible routes to a measurement with uncertainty exceeding current limits on present-day variation in $m_p/m_e$.

  9. High sensitivity to variation in the proton-to-electron mass ratio in O2+

    Science.gov (United States)

    Hanneke, D.; Carollo, R. A.; Lane, D. A.

    2016-11-01

    Molecular vibrational transitions are prime candidates for model-independent searches for variation of the proton-to-electron mass ratio. Searches for present-day variation achieve the highest sensitivity with deep molecular potentials. We identify several high-sensitivity transitions in the deeply bound O2+ molecular ion. These transitions are electric-dipole forbidden and have narrow linewidths. The most sensitive transitions take advantage of an accidental degeneracy between vibrational states in different electronic potentials. We suggest experimentally feasible routes to a measurement with uncertainty below current limits on present-day variation in mp/me .

  10. Rocks, Clays, Water, and Salts: Highly Durable, Infinitely Rechargeable, Eminently Controllable Thermal Batteries for Buildings

    Directory of Open Access Journals (Sweden)

    Alan W. Rempel

    2013-01-01

    Full Text Available Materials that store the energy of warm days, to return that heat during cool nights, have been fundamental to vernacular building since ancient times. Although building with thermally rechargeable materials became a niche pursuit with the advent of fossil fuel-based heating and cooling, energy and climate change concerns have sparked new enthusiasm for these substances of high heat capacity and moderate thermal conductivity: stone, adobe, rammed earth, brick, water, concrete, and more recently, phase-change materials. While broadly similar, these substances absorb and release heat in unique patterns characteristic of their mineralogies, densities, fluidities, emissivities, and latent heats of fusion. Current architectural practice, however, shows little awareness of these differences and the resulting potential to match materials to desired thermal performance. This investigation explores that potential, illustrating the correspondence between physical parameters and thermal storage-and-release patterns in direct-, indirect-, and isolated-gain passive solar configurations. Focusing on heating applications, results demonstrate the superiority of water walls for daytime warmth, the tunability of granite and concrete for evening warmth, and the exceptional ability of phase-change materials to sustain near-constant heat delivery throughout the night.

  11. Highly sensitive ammonia sensor using reflection of light at a glass - photonic crystal interface

    CERN Document Server

    Kuchyanov, A S; Spisser, H; Plekhanov, A I

    2013-01-01

    We have discovered and studied the effect of the asymmetric deformation of a photonic crystal in the form of a change in the slope of the crystal planes as it is filled with a gaseous analyte. We have demonstrated that the use of a new effect leading to the displacement of the stop band against the unchanged spectrum of diffracted white light at the (glass-thin opal film) interface can be used as fast, compact, high sensitive and reproducible optical chemical sensor for ammonia. Low cost and simplicity of sensor fabrication, the response of which can be easily observed without resorting to spectral instruments are therefore likely to be attractive. The basis for high sensitivity (1 ppm), fast response (120 ms) is capillary vapor condensation. On the basis of this effect a cheap high-speed and highly sensitive gas sensors has been built.

  12. Highly sensitive refractive index sensor based on two cascaded microfiber knots with Vernier effect

    Science.gov (United States)

    Xu, Zhilin; Sun, Qizhen; Jia, Weihua; Shum, Perry Ping; Liu, Deming

    2014-05-01

    A highly sensitive refractive index (RI) sensor based on two cascaded microfiber knots with vernier effect is proposed and demonstrated by theoretical arithmetic. Deriving from high proportional evanescent field of microfiber and sharp spectrum fringes induced by vernier effect, a slight change of ambient RI will cause large variation of effective RI and significant wavelength shift of resonant peaks, indicating high sensitivity and resolution of the proposed compound resonator. Numerical analysis demonstrates a high sensitivity of 10000nm/RIU and a resolution of 5.57×10-5 RIU at the ambient RI around 1.33 for the fiber diameter of 1μm and cavity radii of R1 = 500μm, R2 = 547.62μm

  13. Highly sensitive optical chemosensor for the detection of Cu2+ using a rhodamine B spirolatam

    Indian Academy of Sciences (India)

    Gen Hua Wu; Dong Xiang Wang; Da Yu Wu; Yuan Gao; Zhu Qing Wang

    2009-07-01

    Highly sensitive colorimetric chemosensor molecule RHN for selective detection of Cu2+ in mixed CH3CN aqueous media was designed and prepared by incorporating the well-known rhodamine fluorophore and a terdentate O2N binding unit into one molecule. The chemosensor RHN showed not only a reversible, selective, and sensitive absorbance enhancement response to Cu2+, but also a strong colour development against the colourless blank during the sensing event, a feature that would facilitate `naked-eye’ detection.

  14. Practical approach to determine sample size for building logistic prediction models using high-throughput data.

    Science.gov (United States)

    Son, Dae-Soon; Lee, DongHyuk; Lee, Kyusang; Jung, Sin-Ho; Ahn, Taejin; Lee, Eunjin; Sohn, Insuk; Chung, Jongsuk; Park, Woongyang; Huh, Nam; Lee, Jae Won

    2015-02-01

    An empirical method of sample size determination for building prediction models was proposed recently. Permutation method which is used in this procedure is a commonly used method to address the problem of overfitting during cross-validation while evaluating the performance of prediction models constructed from microarray data. But major drawback of such methods which include bootstrapping and full permutations is prohibitively high cost of computation required for calculating the sample size. In this paper, we propose that a single representative null distribution can be used instead of a full permutation by using both simulated and real data sets. During simulation, we have used a dataset with zero effect size and confirmed that the empirical type I error approaches to 0.05. Hence this method can be confidently applied to reduce overfitting problem during cross-validation. We have observed that pilot data set generated by random sampling from real data could be successfully used for sample size determination. We present our results using an experiment that was repeated for 300 times while producing results comparable to that of full permutation method. Since we eliminate full permutation, sample size estimation time is not a function of pilot data size. In our experiment we have observed that this process takes around 30min. With the increasing number of clinical studies, developing efficient sample size determination methods for building prediction models is critical. But empirical methods using bootstrap and permutation usually involve high computing costs. In this study, we propose a method that can reduce required computing time drastically by using representative null distribution of permutations. We use data from pilot experiments to apply this method for designing clinical studies efficiently for high throughput data.

  15. A novel detection platform for parallel monitoring of DNA hybridization with high sensitivity and specificity

    DEFF Research Database (Denmark)

    Yi, Sun; Perch-Nielsen, Ivan R.; Wang, Zhenyu;

    We developed a high-sensitive platform to monior multiple hybridization events in real time. By creating a microoptical array in a polymeric chip, the system combine the excellent discriminative power of supercritical angle fluorescence (SAF) microscopy with high-throughput capabilities...

  16. New approaches to donor crossmatching and successful transplantation of highly sensitized patients.

    Science.gov (United States)

    Delmonico, F L; Fuller, A; Cosimi, A B; Tolkoff-Rubin, N; Russell, P S; Rodey, G E; Fuller, T C

    1983-12-01

    A class I HLA molecule may bear not only a private or unique determinant, but a shared, yet discrete, public epitope. These public determinants occur with a much higher frequency in the random donor population than the associated private determinants--and thus, are encountered more often in random donor blood transfusions and in renal transplantation. Sera from highly sensitized dialysis patients have been reported to contain a restricted number of antibodies to public determinants rather than a diverse array of antibodies directed against the private HLA-AB epitopes. As detailed in this report, comprehensive serum analysis of the public antibodies in highly sensitized transplant candidates has optimized identification of potential crossmatch-compatible donors and has avoided needless crossmatches. During the past two years, the incidence of renal transplantation from cadaveric donors to highly sensitized recipients has doubled at this institution. At 10-25 months following transplantation, 70% of these allografts are functioning. Private HLA class I antigen incompatibility was not a barometer for exclusion in the final donor crossmatch of these highly sensitized recipients. Furthermore, positive donor T cell crossmatches with sera obtained more than six months prior to transplantation may not represent an impediment to successful transplantation. We conclude that the approach of detailed antibody analysis can result in an improved outlook for successful transplantation of more dialysis patients who are highly sensitized to the class I HLA alloantigens.

  17. Ultra high vacuum pumping system and high sensitivity helium leak detector

    Science.gov (United States)

    Myneni, Ganapati Rao

    1997-01-01

    An improved helium leak detection method and apparatus are disclosed which increase the leak detection sensitivity to 10.sup.-13 atm cc s.sup.-1. The leak detection sensitivity is improved over conventional leak detectors by completely eliminating the use of o-rings, equipping the system with oil-free pumping systems, and by introducing measured flows of nitrogen at the entrances of both the turbo pump and backing pump to keep the system free of helium background. The addition of dry nitrogen flows to the system reduces backstreaming of atmospheric helium through the pumping system as a result of the limited compression ratios of the pumps for helium.

  18. Energy Efficient Improvements of Existing Buildings through Building Envelope Upgrade Case Study of High Rise Block of Flats on 76, Boulevard Partizanski Odredi in Karpos IV, Skopje

    OpenAIRE

    2016-01-01

    AIM: This research examines the important issue of energy efficient improvements to the existing building stock through building envelope upgrade. To facilitate this, the energy performance characteristics of the existing building stock were identified with a view to establishing an existing building stock type, where building envelope upgrades can contribute to a higher level of energy efficiency improvements. The literature review along with the selected building precedents was used to esta...

  19. Collapse Scenarios of High-Rise Buildings Using Plastic Limit Analysis

    Directory of Open Access Journals (Sweden)

    G. Liu

    2009-01-01

    Full Text Available The Twin Towers of the World Trade Center (WTC in New York, USA collapsed on 11 September, 2001. The incident is regarded as the most severe disaster for high-rise buildings in history. Investigations into the collapse scenarios are still being conducted. Possible collapse scenarios assessed by local and international experts were reported. Another possible collapse scenario of the WTC based on two hypotheses was proposed in this paper, and the idea of plastic limit analysis was applied to evaluate the approximate limit load. According to the theory analysis and numerical calculations, a conclusion can be drawn that the large fires, aroused by the terrorist attack, play a significant role on the collapse of the WTC.

  20. Investigation of the structural form optimization methods of high-rise buildings

    Institute of Scientific and Technical Information of China (English)

    ZHANG Shihai; WANG Li; OU Jinping; WANG Guangyuan

    2007-01-01

    In this paper, the structural form optimization methods of high-rise buildings based on the expert system (ES), case-based reasoning (CBR), and knowledge discovery in database (KDD) are evaluated systematically. The charac- teristics and shortcomings of each method are pointed out. It is predicted that the incorporation of these three techniques into an intelligent form optimization method will be an important development direction in the future. Finally, the unified intelligent form selection model combined with concepts of ES, CBR, KDD and artificially intelligent beauti- fication is proposed. In consideration of the needs of human beings, machinery and computation, the model has been used for structural design combined with relevant knowledge, means, maneuver and strategy. The model plays an important role and has practical value in the process of artificially intelligent form optimization. It effectively reduces the blindness and failure of computer-aided structural design.

  1. Are Biophilic-Designed Site Office Buildings Linked to Health Benefits and High Performing Occupants?

    Directory of Open Access Journals (Sweden)

    Tonia Gray

    2014-11-01

    Full Text Available This paper discusses the first phase of a longitudinal study underway in Australia to ascertain the broad health benefits of specific types of biophilic design for workers in a building site office. A bespoke site design was formulated to include open plan workspace, natural lighting, ventilation, significant plants, prospect and views, recycled materials and use of non-synthetic materials. Initial data in the first three months was gathered from a series of demographic questions and from interviews and observations of site workers. Preliminary data indicates a strong positive effect from incorporating aspects of biophilic design to boost productivity, ameliorate stress, enhance well-being, foster a collaborative work environment and promote workplace satisfaction, thus contributing towards a high performance workspace. The longitudinal study spanning over two years will track human-plant interactions in a biophilic influenced space, whilst also assessing the concomitant cognitive, social, psychological and physical health benefits for workers.

  2. Are biophilic-designed site office buildings linked to health benefits and high performing occupants?

    Science.gov (United States)

    Gray, Tonia; Birrell, Carol

    2014-11-26

    This paper discusses the first phase of a longitudinal study underway in Australia to ascertain the broad health benefits of specific types of biophilic design for workers in a building site office. A bespoke site design was formulated to include open plan workspace, natural lighting, ventilation, significant plants, prospect and views, recycled materials and use of non-synthetic materials. Initial data in the first three months was gathered from a series of demographic questions and from interviews and observations of site workers. Preliminary data indicates a strong positive effect from incorporating aspects of biophilic design to boost productivity, ameliorate stress, enhance well-being, foster a collaborative work environment and promote workplace satisfaction, thus contributing towards a high performance workspace. The longitudinal study spanning over two years will track human-plant interactions in a biophilic influenced space, whilst also assessing the concomitant cognitive, social, psychological and physical health benefits for workers.

  3. Experimental and Simulation of Gamma Radiation Dose Rate for High Exposure Building Material

    CERN Document Server

    Abbasi, Akbar

    2015-01-01

    Natural radioactivity concentrations in high exposure building materials are commonly used in Iran, which is measured a direct exposure by using {\\gamma}-ray spectrometry. The values for 226Ra, 232Th and 40K were in the ranges 3.8 - 94.2, 6.5 - 172.2 and 556.9 - 1539.2 Bqkg-1, respectively. The absorbed dose rates in the standard dwelling room due to 238U, 232Th series and 40K were calculated with MCNPX code. The simulation and experimental results were between 7.95 - 41.74 and 8.36 - 39.99 nGy h-1, respectively. These results were compared with experimental outing and there was overlap closely. The simulation results are able to develop for any kind of dwelling places.

  4. Highly sensitive ion-sensitive field-effect transistor sensor using fully transparent amorphous In–Ga–Zn–O thin-film transistors

    Science.gov (United States)

    Ahn, Min-Ju; Lim, Cheol-Min; Cho, Won-Ju

    2017-03-01

    In this study, a highly sensitive ion-sensitive field-effect transistor (ISFET) sensor was developed using fully transparent amorphous In–Ga–Zn–O thin-film transistors fabricated on a glass substrate. To overcome the issues associated with conventional ISFETs, such as low sensitivity and poor reliability, a dual-gate (DG) operating mode was employed, which is able to significantly amplify the sensitivity through capacitive coupling between the front and back gate dielectrics. As a result, when compared to the sensitivity in the single-gate mode, the DG mode exhibited a high sensitivity of 269.3 mV/pH, which is beyond the Nernst response limit.

  5. Future Premature Mortality Due to O3, Secondary Inorganic Aerosols and Primary PM in Europe — Sensitivity to Changes in Climate, Anthropogenic Emissions, Population and Building Stock

    Directory of Open Access Journals (Sweden)

    Camilla Geels

    2015-03-01

    Full Text Available Air pollution is an important environmental factor associated with health impacts in Europe and considerable resources are used to reduce exposure to air pollution through emission reductions. These reductions will have non-linear effects on exposure due, e.g., to interactions between climate and atmospheric chemistry. By using an integrated assessment model, we quantify the effect of changes in climate, emissions and population demography on exposure and health impacts in Europe. The sensitivity to the changes is assessed by investigating the differences between the decades 2000–2009, 2050–2059 and 2080–2089. We focus on the number of premature deaths related to atmospheric ozone, Secondary Inorganic Aerosols and primary PM. For the Nordic region we furthermore include a projection on how population exposure might develop due to changes in building stock with increased energy efficiency. Reductions in emissions cause a large significant decrease in mortality, while climate effects on chemistry and emissions only affects premature mortality by a few percent. Changes in population demography lead to a larger relative increase in chronic mortality than the relative increase in population. Finally, the projected changes in building stock and infiltration rates in the Nordic indicate that this factor may be very important for assessments of population exposure in the future.

  6. Future Premature Mortality Due to O3, Secondary Inorganic Aerosols and Primary PM in Europe — Sensitivity to Changes in Climate, Anthropogenic Emissions, Population and Building Stock

    Science.gov (United States)

    Geels, Camilla; Andersson, Camilla; Hänninen, Otto; Lansø, Anne Sofie; Schwarze, Per E.; Ambelas Skjøth, Carsten; Brandt, Jørgen

    2015-01-01

    Air pollution is an important environmental factor associated with health impacts in Europe and considerable resources are used to reduce exposure to air pollution through emission reductions. These reductions will have non-linear effects on exposure due, e.g., to interactions between climate and atmospheric chemistry. By using an integrated assessment model, we quantify the effect of changes in climate, emissions and population demography on exposure and health impacts in Europe. The sensitivity to the changes is assessed by investigating the differences between the decades 2000–2009, 2050–2059 and 2080–2089. We focus on the number of premature deaths related to atmospheric ozone, Secondary Inorganic Aerosols and primary PM. For the Nordic region we furthermore include a projection on how population exposure might develop due to changes in building stock with increased energy efficiency. Reductions in emissions cause a large significant decrease in mortality, while climate effects on chemistry and emissions only affects premature mortality by a few percent. Changes in population demography lead to a larger relative increase in chronic mortality than the relative increase in population. Finally, the projected changes in building stock and infiltration rates in the Nordic indicate that this factor may be very important for assessments of population exposure in the future. PMID:25749320

  7. Success Factors for Building and Managing High Performance Global Virtual Teams

    Directory of Open Access Journals (Sweden)

    Dan S. Nguyen

    2013-04-01

    Full Text Available With the phenomenon of globalization, the global virtual team (GVT is widely recognized as an innovative functioning atmosphere that relies mostly on information communication technologies (ICTs. A global virtual team is specified as a different entity whose members come from different global work locations, may not have a mutual background, is organizationally scattered, collaborate using asynchronous and synchronous ICTs, and frequently built on an impromptu basis. Hence, boundaries such as geographical space, time, and organizations are no longer conceived as major impediments for small teams to function together. Yet, numerous GVT work challenges remain as these teams involve in globally distributed collaborative efforts. Numerous of the complexities emerge from workplaces factors (e.g., cultural, functional, and organizational differences, team technologies usage, management approaches, leadership dilemmas, and technological impediments. The purpose of this paper is to present and synthesize the success factors generally accepted as critical in building and managing high performance GVTs. These success factors consisted of GVT (e.g., structure, member’ competencies, commitment and trust, communications, goals, and collaboration, leading GVTs (e.g., leadership competencies, skills, and styles and so on, management (e.g., project, risk, team, knowledge and skills, and information managements, workplace factors (e.g., cultural, functional and organizational differences, technologies (e.g., development tools, and information communication technologies, and standards of excellence and external support. Organizational managers and practitioners from various industries who are building or managing GVTs could be of benefits with the researcher’s study outcomes by implementing or developing strategies or processes that could improve GVT performance for long term sustainable development. High performances GVT outcomes include improve team overall

  8. The Design and Optimization of a Highly Sensitive and Overload-Resistant Piezoresistive Pressure Sensor

    Directory of Open Access Journals (Sweden)

    Xiawei Meng

    2016-03-01

    Full Text Available A piezoresistive pressure sensor with a beam-membrane-dual-island structure is developed for micro-pressure monitoring in the field of aviation, which requires great sensitivity and overload resistance capacity. The design, fabrication, and test of the sensor are presented in this paper. By analyzing the stress distribution of sensitive elements using the finite element method, a novel structure incorporating sensitive beams with a traditional bossed diaphragm is built up. The proposed structure proved to be advantageous in terms of high sensitivity and high overload resistance compared with the conventional bossed diaphragm and flat diaphragm structures. Curve fittings of surface stress and deflection based on ANSYS simulation results are performed to establish the sensor equations. Fabricated on an n-type single crystal silicon wafer, the sensor chips are wire-bonded to a printed circuit board (PCB and packaged for experiments. The static and dynamic characteristics are tested and discussed. Experimental results show that the sensor has a sensitivity as high as 17.339 μV/V/Pa in the range of 500 Pa at room temperature, and a high overload resistance of 200 times overpressure. Due to the excellent performance, the sensor can be applied in measuring micro-pressure lower than 500 Pa.

  9. Highly sensitive giant magnetoimpedance in a solenoid containing FeCo-based ribbon

    Institute of Scientific and Technical Information of China (English)

    Fang Yun-Zhang; Xu Qi-Ming; Zheng Jin-Ju; Wu Feng-Min; Ye Hui-Qun; Si Jian-Xiao; Zheng Jian-Long; Fan Xiao-Zhen; Yang Xiao-Hong

    2012-01-01

    The highly sensitive giant magneto-impedance effect in a solenoid containing a magnetic core of Fe36Co36Nb4Si4.sB19.2 (FeCo-based) ribbon under a weak magnetic field (WMF) is presented in this paper. The FeCo-based amorphous ribbon is prepared by single roller quenching and annealed with Joule heat in a flowing nitrogen atmosphere.The giant magnetoimpedance effect in solenoid (GMIES) profiles are measured with an HP4294A impedance analyzer.The result shows that the GMIES responds to the WMF sensitively (as high as 1580 %/A·m-l).The high sensitivity can be obtained in a moderate narrow range of annealing current density (30-34 A/mm2) and closely depends on the driven current frequency.The highest sensitivity (1580 %/A.m-1) is obtained when the FeCobased amorphous ribbon is annealed at 32 A/mm2 for 10 min and then driven with an alterning current (AC) at the frequency of 350 kHz.The highly sensitive GMIES under the WMF may result from the multiple magnetic-anisotropic structure,which is induced by the temperature gradient produced during Joule-heating the ribbon.

  10. High degree gravitational sensitivity from Mars orbiters for the GMM-1 gravity model

    Science.gov (United States)

    Lerch, F. J.; Smith, D. E.; Chan, J. C.; Patel, G. B.; Chinn, D. S.

    1994-01-01

    Orbital sensitivity of the gravity field for high degree terms (greater than 30) is analyzed on satellites employed in a Goddard Mars Model GMM-1, complete in spherical harmonics through degree and order 50. The model is obtained from S-band Doppler data on Mariner 9 (M9), Viking Orbiter 1 (VO1), and Viking Orbiter 2 (VO2) spacecraft, which were tracked by the NASA Deep Space Network on seven different highly eccentric orbits. The main sensitivity of the high degree terms is obtained from the VO1 and VO2 low orbits (300 km periapsis altitude), where significant spectral sensitivity is seen for all degrees out through degree 50. The velocity perturbations show a dominant effect at periapsis and significant effects out beyond the semi-latus rectum covering over 180 degrees of the orbital groundtrack for the low altitude orbits. Because of the wideband of periapsis motion covering nearly 180 degrees in w and +39 degrees in latitude coverage, the VO1 300 km periapsis altitude orbit with inclination of 39 degrees gave the dominant sensitivity in the GMM-1 solution for the high degree terms. Although the VO2 low periapsis orbit has a smaller band of periapsis mapping coverage, it strongly complements the VO1 orbit sensitivity for the GMM-1 solution with Doppler tracking coverage over a different inclination of 80 degrees.

  11. The Design and Optimization of a Highly Sensitive and Overload-Resistant Piezoresistive Pressure Sensor.

    Science.gov (United States)

    Meng, Xiawei; Zhao, Yulong

    2016-03-09

    A piezoresistive pressure sensor with a beam-membrane-dual-island structure is developed for micro-pressure monitoring in the field of aviation, which requires great sensitivity and overload resistance capacity. The design, fabrication, and test of the sensor are presented in this paper. By analyzing the stress distribution of sensitive elements using the finite element method, a novel structure incorporating sensitive beams with a traditional bossed diaphragm is built up. The proposed structure proved to be advantageous in terms of high sensitivity and high overload resistance compared with the conventional bossed diaphragm and flat diaphragm structures. Curve fittings of surface stress and deflection based on ANSYS simulation results are performed to establish the sensor equations. Fabricated on an n-type single crystal silicon wafer, the sensor chips are wire-bonded to a printed circuit board (PCB) and packaged for experiments. The static and dynamic characteristics are tested and discussed. Experimental results show that the sensor has a sensitivity as high as 17.339 μV/V/Pa in the range of 500 Pa at room temperature, and a high overload resistance of 200 times overpressure. Due to the excellent performance, the sensor can be applied in measuring micro-pressure lower than 500 Pa.

  12. The Sensitivity of Adolescent School-Based Hearing Screens Is Significantly Improved by Adding High Frequencies.

    Science.gov (United States)

    Sekhar, Deepa L; Zalewski, Thomas R; Beiler, Jessica S; Czarnecki, Beth; Barr, Ashley L; King, Tonya S; Paul, Ian M

    2016-12-01

    High frequency hearing loss (HFHL), often related to hazardous noise, affects one in six U.S. adolescents. Yet, only 20 states include school-based hearing screens for adolescents. Only six states test multiple high frequencies. Study objectives were to (1) compare the sensitivity of state school-based hearing screens for adolescents to gold standard sound-treated booth testing and (2) consider the effect of adding multiple high frequencies and two-step screening on sensitivity/specificity. Of 134 eleventh-grade participants (2013-2014), 43 of the 134 (32%) did not pass sound-treated booth testing, and 27 of the 43 (63%) had HFHL. Sensitivity/specificity of the most common protocol (1,000, 2,000, 4,000 Hz at 20 dB HL) for these hearing losses was 25.6% (95% confidence interval [CI] = [13.5, 41.2]) and 85.7% (95% CI [76.8, 92.2]), respectively. A protocol including 500, 1,000, 2,000, 4,000, 6,000 Hz at 20 dB HL significantly improved sensitivity to 76.7% (95% CI [61.4, 88.2]), p < .001. Two-step screening maintained specificity (84.6%, 95% CI [75.5, 91.3]). Adolescent school-based hearing screen sensitivity improves with high frequencies.

  13. Classification of High-Rise Residential Building Facilities: A Descriptive Survey on 170 Housing Scheme in Klang Valley

    Directory of Open Access Journals (Sweden)

    Abd Wahab Siti Rashidah Hanum

    2016-01-01

    Full Text Available High-rise residential building is a type of housing that has multi-dwelling units built on the same land. This type of housing has become popular each year in urban area due to the increasing cost of land. There are several common facilities provided in high-rise residential building. For example playground, swimming pool, gymnasium, 24 hours security system such as CCTV, access card and so on. Thus, maintenance works of the common facilities must be well organised. The purpose of this paper is to identify the classification of facilities provided at high rise residential building. The survey was done on 170 high-rise residential schemes by using stratified random sampling technique. The scope of this research is within Klang Valley area. This area is rapidly developed with high-rise residential building. The objective of this survey is to list down all the facilities provided in each sample of the schemes. The result, there are nine classification of facilities provided for high-rise residential building.

  14. A Highly Sensitive CMOS Digital Hall Sensor for Low Magnetic Field Applications

    Directory of Open Access Journals (Sweden)

    Li Li

    2012-02-01

    Full Text Available Integrated CMOS Hall sensors have been widely used to measure magnetic fields. However, they are difficult to work with in a low magnetic field environment due to their low sensitivity and large offset. This paper describes a highly sensitive digital Hall sensor fabricated in 0.18 μm high voltage CMOS technology for low field applications. The sensor consists of a switched cross-shaped Hall plate and a novel signal conditioner. It effectively eliminates offset and low frequency 1/f noise by applying a dynamic quadrature offset cancellation technique. The measured results show the optimal Hall plate achieves a high current related sensitivity of about 310 V/AT. The whole sensor has a remarkable ability to measure a minimum ±2 mT magnetic field and output a digital Hall signal in a wide temperature range from −40 °C to 120 °C.

  15. A Highly Sensitive CMOS Digital Hall Sensor for Low Magnetic Field Applications

    Science.gov (United States)

    Xu, Yue; Pan, Hong-Bin; He, Shu-Zhuan; Li, Li

    2012-01-01

    Integrated CMOS Hall sensors have been widely used to measure magnetic fields. However, they are difficult to work with in a low magnetic field environment due to their low sensitivity and large offset. This paper describes a highly sensitive digital Hall sensor fabricated in 0.18 μm high voltage CMOS technology for low field applications. The sensor consists of a switched cross-shaped Hall plate and a novel signal conditioner. It effectively eliminates offset and low frequency 1/f noise by applying a dynamic quadrature offset cancellation technique. The measured results show the optimal Hall plate achieves a high current related sensitivity of about 310 V/AT. The whole sensor has a remarkable ability to measure a minimum ±2 mT magnetic field and output a digital Hall signal in a wide temperature range from −40 °C to 120 °C. PMID:22438758

  16. Photon Counting System for High-Sensitivity Detection of Bioluminescence at Optical Fiber End.

    Science.gov (United States)

    Iinuma, Masataka; Kadoya, Yutaka; Kuroda, Akio

    2016-01-01

    The technique of photon counting is widely used for various fields and also applicable to a high-sensitivity detection of luminescence. Thanks to recent development of single photon detectors with avalanche photodiodes (APDs), the photon counting system with an optical fiber has become powerful for a detection of bioluminescence at an optical fiber end, because it allows us to fully use the merits of compactness, simple operation, highly quantum efficiency of the APD detectors. This optical fiber-based system also has a possibility of improving the sensitivity to a local detection of Adenosine triphosphate (ATP) by high-sensitivity detection of the bioluminescence. In this chapter, we are introducing a basic concept of the optical fiber-based system and explaining how to construct and use this system.

  17. Fabrication of a highly sensitive penicillin sensor based on charge transfer techniques.

    Science.gov (United States)

    Lee, Seung-Ro; Rahman, M M; Sawada, Kazuaki; Ishida, Makoto

    2009-03-15

    A highly sensitive penicillin biosensor based on a charge-transfer technique (CTTPS) has been fabricated and demonstrated in this paper. CTTPS comprised a charge accumulation technique for penicilloic acid and H(+) ions perception system. With the proposed CTTPS, it is possible to amplify the sensing signals without external amplifier by using the charge accumulation cycles. The fabricated CTTPS exhibits excellent performance for penicillin detection and exhibit a high-sensitivity (47.852 mV/mM), high signal-to-noise ratio (SNR), large span (1445 mV), wide linear range (0-25 mM), fast response time (penicillin sensor and exhibited almost eight times greater sensitivity as compared to ISFET (6.56 mV/mM). The sensor system is implemented for the measurement of the penicillin concentration in penicillin fermentation broth.

  18. Repeated high-intensity exercise modulates Ca(2+) sensitivity of human skeletal muscle fibers

    DEFF Research Database (Denmark)

    Gejl, K D; Hvid, L G; Willis, S J;

    2016-01-01

    The effects of short-term high-intensity exercise on single fiber contractile function in humans are unknown. Therefore, the purposes of this study were: (a) to access the acute effects of repeated high-intensity exercise on human single muscle fiber contractile function; and (b) to examine whether...... the fourth sprint with respect to Ca(2+) sensitivity and maximal Ca(2+) -activated force. To investigate the oxidative effects of exercise on single fiber contractile function, a subset of fibers was incubated with dithiothreitol (DTT) before analysis. Ca(2+) sensitivity was enhanced by exercise in both MHC...... I (17%, P exercise. In conclusion, repeated high-intensity exercise increased Ca(2+) sensitivity in both MHC I and MHC II...

  19. Design and Synthesis of an MOF Thermometer with High Sensitivity in the Physiological Temperature Range.

    Science.gov (United States)

    Zhao, Dian; Rao, Xingtang; Yu, Jiancan; Cui, Yuanjing; Yang, Yu; Qian, Guodong

    2015-12-07

    An important result of research on mixed-lanthanide metal-organic frameworks (M'LnMOFs) is the realization of highly sensitive ratiometric luminescent thermometers. Here, we report the design and synthesis of the new M'LnMOF Tb0.80Eu0.20BPDA with high relative sensitivity in the physiological temperature regime (298-318 K). The emission intensity and luminescence lifetime were investigated and compared to those of existing materials. It was found that the temperature-dependent luminescence properties of Tb0.80Eu0.20BPDA are strongly associated with the distribution of the energy levels of the ligand. Such a property can be useful in the design of highly sensitive M'LnMOF thermometers.

  20. Optical transitions in highly charged californium ions with high sensitivity to variation of the fine-structure constant.

    Science.gov (United States)

    Berengut, J C; Dzuba, V A; Flambaum, V V; Ong, A

    2012-08-17

    We study electronic transitions in highly charged Cf ions that are within the frequency range of optical lasers and have very high sensitivity to potential variations in the fine-structure constant, α. The transitions are in the optical range despite the large ionization energies because they lie on the level crossing of the 5f and 6p valence orbitals in the thallium isoelectronic sequence. Cf(16+) is a particularly rich ion, having several narrow lines with properties that minimize certain systematic effects. Cf(16+) has very large nuclear charge and large ionization energy, resulting in the largest α sensitivity seen in atomic systems. The lines include positive and negative shifters.

  1. In vivo emergence of HIV-1 highly sensitive to neutralizing antibodies.

    Directory of Open Access Journals (Sweden)

    Marlén M I Aasa-Chapman

    Full Text Available BACKGROUND: The rapid and continual viral escape from neutralizing antibodies is well documented in HIV-1 infection. Here we report in vivo emergence of viruses with heightened sensitivity to neutralizing antibodies, sometimes paralleling the development of neutralization escape. METHODOLOGY/PRINCIPAL FINDINGS: Sequential viral envs were amplified from seven HIV-1 infected men monitored from seroconversion up to 5 years after infection. Env-recombinant infectious molecular clones were generated and tested for coreceptor use, macrophage tropism and neutralization sensitivity to homologous and heterologous serum, soluble CD4 and monoclonal antibodies IgG1b12, 2G12 and 17b. We found that HIV-1 evolves sensitivity to contemporaneous neutralizing antibodies during infection. Neutralization sensitive viruses grow out even when potent autologous neutralizing antibodies are present in patient serum. Increased sensitivity to neutralization was associated with susceptibility of the CD4 binding site or epitopes induced after CD4 binding, and mediated by complex envelope determinants including V3 and V4 residues. The development of neutralization sensitive viruses occurred without clinical progression, coreceptor switch or change in tropism for primary macrophages. CONCLUSIONS: We propose that an interplay of selective forces for greater virus replication efficiency without the need to resist neutralizing antibodies in a compartment protected from immune surveillance may explain the temporal course described here for the in vivo emergence of HIV-1 isolates with high sensitivity to neutralizing antibodies.

  2. On the Design of High-Rise Buildings for Multihazard: Fundamental Differences between Wind and Earthquake Demand

    Directory of Open Access Journals (Sweden)

    Aly Mousaad Aly

    2015-01-01

    Full Text Available In the past few decades, high-rise buildings have received a renewed interest in many city business locations, where land is scarce, as per their economics, sustainability, and other benefits. Taller and taller towers are being built everywhere in the world. However, the increased frequency of multihazard disasters makes it challenging to balance between a resilient and sustainable construction. Accordingly, it is essential to understand the behavior of such structures under multihazard loadings, in order to apply such knowledge to design. The results obtained from the dynamic analysis of two different high-rise buildings (54-story and 76-story buildings investigated in the current study indicate that earthquake loads excite higher modes that produce lower interstory drift, compared to wind loads, but higher accelerations that occur for a shorter time. Wind-induced accelerations may have comfort and serviceability concerns, while excessive interstory drifts can cause security issues. The results also show that high-rise and slender buildings designed for wind may be safe under moderate earthquake loads, regarding the main force resisting system. Nevertheless, nonstructural components may present a significant percentage of loss exposure of buildings to earthquakes due to higher floor acceleration. Consequently, appropriate damping/control techniques for tall buildings are recommended for mitigation under multihazard.

  3. Highly Sensitive and Selective Ethanol Sensor Fabricated with In-Doped 3DOM ZnO.

    Science.gov (United States)

    Wang, Zhihua; Tian, Ziwei; Han, Dongmei; Gu, Fubo

    2016-03-02

    ZnO is an important n-type semiconductor sensing material. Currently, much attention has been attracted to finding an effective method to prepare ZnO nanomaterials with high sensing sensitivity and excellent selectivity. A three-dimensionally ordered macroporous (3DOM) ZnO nanostructure with a large surface area is beneficial to gas and electron transfer, which can enhance the gas sensitivity of ZnO. Indium (In) doping is an effective way to improve the sensing properties of ZnO. In this paper, In-doped 3DOM ZnO with enhanced sensitivity and selectivity has been synthesized by using a colloidal crystal templating method. The 3DOM ZnO with 5 at. % of In-doping exhibits the highest sensitivity (∼88) to 100 ppm ethanol at 250 °C, which is approximately 3 times higher than that of pure 3DOM ZnO. The huge improvement to the sensitivity to ethanol was attributed to the increase in the surface area and the electron carrier concentration. The doping by In introduces more electrons into the matrix, which is helpful for increasing the amount of adsorbed oxygen, leading to high sensitivity. The In-doped 3DOM ZnO is a promising material for a new type of ethanol sensor.

  4. Effects of intrinsic magnetostriction on tube-topology magnetoelectric sensors with high magnetic field sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Gillette, Scott M.; Fitchorov, Trifon; Obi, Ogheneyunume; Chen, Yajie, E-mail: y.chen@neu.edu; Harris, Vincent G. [Department of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts 02115 (United States); Jiang, Liping; Hao, Hongbo; Wu, Shuangxia [Baotou Research Institute of Rare Earths, Baotou, Inner Mongolia 014030 (China)

    2014-05-07

    Three quasi-one-dimensional magnetoelectric (ME) magnetic field sensors, each with a different magnetostrictive wire material, were investigated in terms of sensitivity and noise floor. Magnetostrictive Galfenol, iron-cobalt-vanadium, and iron-nickel wires were examined. Sensitivity profiles, hysteresis effects, and noise floor measurements for both optimally biased and zero-biased conditions are presented. The FeNi wire (FN) exhibits high sensitivity (5.36 mV/Oe) at bias fields below 22 Oe and an optimal bias of 10 Oe, whereas FeGa wire (FG) exhibits higher sensitivity (6.89 mW/Oe) at bias fields >22 Oe. The sensor of FeCoV wire (FC) presents relatively low sensitivity (2.12 mV/Oe), due to low magnetostrictive coefficient. Each ME tube-topology sensor demonstrates relatively high sensitivity at zero bias field, which results from a magnetic shape anisotropy and internal strain of the thin magnetostrictive wire.

  5. Human Factors in Green Office Building Design: The Impact of Workplace Green Features on Health Perceptions in High-Rise High-Density Asian Cities

    Directory of Open Access Journals (Sweden)

    Fei Xue

    2016-10-01

    Full Text Available There is a growing concern about human factors in green building, which is imperative in high-rise high-density urban environments. This paper describes our attempts to explore the influence of workplace green features (such as green certification, ventilation mode, and building morphology on health perceptions (personal sensation, sensorial assumptions, healing performance based on a survey in Hong Kong and Singapore. The results validated the relationship between green features and health perceptions in the workplace environment. Remarkably, participants from the air-conditioned offices revealed significant higher concerns about health issues than those participants from the mixed-ventilated offices. The mixed-ventilation design performs as a bridge to connect the indoor environment and outdoor space, which enables people to have contact with nature. Additionally, the preferred building morphology of the workplace is the pattern of a building complex instead of a single building. The complex form integrates the configuration of courtyards, podium gardens, green terrace, public plaza, and other types of open spaces with the building clusters, which contributes to better health perceptions. This research contributes to the rationalization and optimization of passive climate-adaptive design strategies for green buildings in high-density tropical or subtropical cities.

  6. High-Sensitivity X-ray Polarimetry with Amorphous Silicon Active-Matrix Pixel Proportional Counters

    Science.gov (United States)

    Black, J. K.; Deines-Jones, P.; Jahoda, K.; Ready, S. E.; Street, R. A.

    2003-01-01

    Photoelectric X-ray polarimeters based on pixel micropattern gas detectors (MPGDs) offer order-of-magnitude improvement in sensitivity over more traditional techniques based on X-ray scattering. This new technique places some of the most interesting astronomical observations within reach of even a small, dedicated mission. The most sensitive instrument would be a photoelectric polarimeter at the focus of 2 a very large mirror, such as the planned XEUS. Our efforts are focused on a smaller pathfinder mission, which would achieve its greatest sensitivity with large-area, low-background, collimated polarimeters. We have recently demonstrated a MPGD polarimeter using amorphous silicon thin-film transistor (TFT) readout suitable for the focal plane of an X-ray telescope. All the technologies used in the demonstration polarimeter are scalable to the areas required for a high-sensitivity collimated polarimeter. Leywords: X-ray polarimetry, particle tracking, proportional counter, GEM, pixel readout

  7. Design optimization of highly sensitive LSPR enhanced surface plasmon resonance biosensors with nanoholes

    Institute of Scientific and Technical Information of China (English)

    Bin Wu; Qingkang Wang

    2008-01-01

    For breaking through the sensitivity limitation of conventional surface plasmon resonance (SPR) biosensors, novel highly sensitive SPR biosensors with Au nanoparticles and nanogratings enhancement have been proposed recently.But in practice, these structures have obvious disadvantages.In this study, a nanohole based sensitivity enhancement SPR biosensor is proposed and the influence of different structural parameters on the performance is investigated by using rigorous coupled wave analysis (RCWA).Electromagnetic field distributions around the nanohole are also given out to directly explain the performance difference for various structural parameters.The results indicate that significant sensitivity increase is associated with localized surface plasmons (LSPs) excitation mediated by nanoholes.Except to outcome the weakness of other LSP based biosensors, larger resonance angle shift, reflectance amplitude, and sharper SPR curves' width are obtained simultaneously under optimized structural parameters.

  8. An analysis of the benefits of photovoltaic-coated glazing on owning and operating costs of high rise commercial buildings

    Science.gov (United States)

    Sylvester, Keith Everette

    Energy efficient glazing is necessary to reduce heat gains or losses that contribute to the high-energy use of buildings. However, high-rise commercial buildings that use energy efficient glazing are still consumptive. To reduce their energy use further, recent studies have integrated photovoltaic glazed window systems into the building shell. With limited light transmittance due to their required production of electricity, photovoltaic glazed windows can be developed with thermal properties similar to Low-E coatings. Consequently, these window systems can reduce operating costs of buildings without reducing the human satisfaction of the built environment. To understand the relationship between photovoltaic windows, energy use and human satisfaction, this study investigates the effects of photovoltaic glazed windows on energy use of large commercial buildings and includes an assessment of the overall human satisfaction of the workers within photovoltaic glazed office spaces. This study targets high-rise commercial buildings and their occupants in urban centers of the four census regions---North, Northeast, South, and Midwest. A prototypical building was used to develop the base case simulations for the DOE-2 energy simulation program and the PV F-Chart photovoltaic analysis program. By substituting the appropriate variable in the base case simulation for each site, building was simulated to evaluate the impact of the PV glazing on the building's heat loss/gaining as well as the amount of electricity that could be expected from the PV. To test for human satisfaction, a survey was performed to assess the overall preference of the subjects to the office spaces using the photovoltaic glazed windows. An analysis of the variance was also conducted to test for significantly different treatment means. Overall, the findings of this study show that photovoltaic windows significantly decrease the energy used by high-rise commercial buildings. Payback periods 11 to 20 years

  9. Highly Sensitive Colorimetric Detection of Ochratoxin A by a Label-Free Aptamer and Gold Nanoparticles

    Directory of Open Access Journals (Sweden)

    Yunxia Luan

    2015-12-01

    Full Text Available A label-free aptamer-based assay for the highly sensitive and specific detection of Ochratoxin A (OTA was developed using a cationic polymer and gold nanoparticles (AuNPs. The OTA aptamer was used as a recognition element for the colorimetric detection of OTA based on the aggregation of AuNPs by the cationic polymer. By spectroscopic quantitative analysis, the colorimetric assay could detect OTA down to 0.009 ng/mL with high selectivity in the presence of other interfering toxins. This study offers a new alternative in visual detection methods that is rapid and sensitive for OTA detection.

  10. Miniaturized Fiber-Optic Fabry-Perot Interferometer for Highly Sensitive Refractive Index Measurement

    Institute of Scientific and Technical Information of China (English)

    Ming Deng; Tao Zhu; Yun-Jiang Rao; Hong Li

    2008-01-01

    This paper presents a novel miniaturized fiber-optic Fabry-Peort interferometer (FPI) for highly sensitive refractive index measurement. This device was tested for the refractive indices of various liquids including acetone and ethanol at room temperature. The sensitivity for measurement of refractive index change of ethanol is 1138 nm/RIU at the wavelength of 1550 nm. In addition, the sensor fabrication is simple including only cleaving, splicing, and etching. The signal is stable with high visibility. Therefore, it provides a valuable tool in biological and chemical applications.

  11. Real-Time, Single-Step Bioassay Using Nanoplasmonic Resonator With Ultra-High Sensitivity

    Science.gov (United States)

    Zhang, Xiang (Inventor); Ellman, Jonathan A. (Inventor); Chen, Fanqing Frank (Inventor); Su, Kai-Hang (Inventor); Wei, Qi-Huo (Inventor); Sun, Cheng (Inventor)

    2014-01-01

    A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.

  12. Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xiang; Ellman, Jonathan A; Chen, Fanqing Frank; Su, Kai-Hang; Wei, Qi-Huo; Sun, Cheng

    2014-04-01

    A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.

  13. Highly sensitive, non-invasive detection of colorectal cancer mutations using single molecule, third generation sequencing

    Directory of Open Access Journals (Sweden)

    Giancarlo Russo

    2015-12-01

    We present the first study that applies the high read accuracy and depth of single molecule, real time, circular consensus sequencing (SMRT-CCS to the detection of mutations in stool DNA in order to provide a non-invasive, sensitive and accurate test for CRC. In stool DNA isolated from patients diagnosed with adenocarcinoma, we are able to detect mutations at frequencies below 0.5% with no false positives. This approach establishes a foundation for a non-invasive, highly sensitive assay to screen the population for CRC and the early stage adenomas that lead to CRC.

  14. Highly Sensitive Colorimetric Detection of Ochratoxin A by a Label-Free Aptamer and Gold Nanoparticles.

    Science.gov (United States)

    Luan, Yunxia; Chen, Jiayi; Li, Cheng; Xie, Gang; Fu, Hailong; Ma, Zhihong; Lu, Anxiang

    2015-12-10

    A label-free aptamer-based assay for the highly sensitive and specific detection of Ochratoxin A (OTA) was developed using a cationic polymer and gold nanoparticles (AuNPs). The OTA aptamer was used as a recognition element for the colorimetric detection of OTA based on the aggregation of AuNPs by the cationic polymer. By spectroscopic quantitative analysis, the colorimetric assay could detect OTA down to 0.009 ng/mL with high selectivity in the presence of other interfering toxins. This study offers a new alternative in visual detection methods that is rapid and sensitive for OTA detection.

  15. Seed oil polyphenols: rapid and sensitive extraction method and high resolution-mass spectrometry identification.

    Science.gov (United States)

    Koubaa, Mohamed; Mhemdi, Houcine; Vorobiev, Eugène

    2015-05-01

    Phenolic content is a primary parameter for vegetables oil quality evaluation, and directly involved in the prevention of oxidation and oil preservation. Several methods have been reported in the literature for polyphenols extraction from seed oil but the approaches commonly used remain manually handled. In this work, we propose a rapid and sensitive method for seed oil polyphenols extraction and identification. For this purpose, polyphenols were extracted from Opuntia stricta Haw seed oil, using high frequency agitation, separated, and then identified using a liquid chromatography-high resolution mass spectrometry method. Our results showed good sensitivity and reproducibility of the developed methods.

  16. Effect of high gamma-doses in the sensitization of natural quartz for thermoluminescence dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Khoury, H.J.; Guzzo, P.L.; Brito, S.B. [Universidade Federal de Pernambuco, 50740-540 Recife PE (Brazil)

    2006-07-01

    Sensitization is an important effect in radiation dosimetry using thermoluminescent (TL materials where the enhancement of sensitivity is a desirable feature. Until known, the investigation of sensitization in quartz has been restricted to its first glow peak appearing around 110 C. In addition, the sensitization process has been essentially produced by heat-treatments in powdered quartz. The aim of this study is to investigate the sensitization process in the second glow peak of crystalline quartz using high doses of gamma irradiation. For this, five lots of samples were prepared from quartz single crystals issued from different geologies in Brazil. Chips of 5 x 5 x 1 mm{sup 3} (60 mg) were cut and lapped parallel to the (0001) plane. The specimens were initially irradiated with doses of gamma radiation of {sup 137} Cs in the range of 10 mGy to 10 Gy in order to determine its TL response curve. After that, the specimens were submitted to successive high doses of gamma-irradiation with {sup 60} Co from 25 kGy to 350 kGy. After each irradiation, the TL response curves to gamma radiation of {sup 137} Cs were determined for each quartz lot irradiated in the range of 2 to 20 mGy. The TL measurements were carried out with a 2800M Victoreen reader using the step mode. The step parameters were set in 10 s from 30 to 160 C (first region) and in 20 s from 160 to 320 C (second region). The absolute TL signal used to obtain the calibration curves represented the sum of electric charges under the glow peak appearing in the second region. The results showed that the TL response of the quartz studied increased with the dose sensitization, so that the TL response for 10mGy of {sup 137} Cs radiation varied from 0.05 nC/mg for the quartz without sensitization to 10 nC/mg after a sensitization with 50 kGy of gamma radiation of {sup 60} Co. The effect of sensitization with high doses of gamma irradiation was clearly observed for three quartz lots and it was observed that the high

  17. Electro-optic comb based real time ultra-high sensitivity phase noise measurement system for high frequency microwaves.

    Science.gov (United States)

    Kuse, N; Fermann, M E

    2017-06-06

    Recent progress in ultra low phase noise microwave generation indispensably depends on ultra low phase noise characterization systems. However, achieving high sensitivity currently relies on time consuming averaging via cross correlation, which sometimes even underestimates phase noise because of residual correlations. Moreover, extending high sensitivity phase noise measurements to microwaves beyond 10 GHz is very difficult because of the lack of suitable high frequency microwave components. In this work, we introduce a delayed self-heterodyne method in conjunction with sensitivity enhancement via the use of higher order comb modes from an electro-optic comb for ultra-high sensitivity phase noise measurements. The method obviates the need for any high frequency RF components and has a frequency measurement range limited only by the bandwidth (100 GHz) of current electro-optic modulators. The estimated noise floor is as low as -133 dBc/Hz, -155 dBc/Hz, -170 dBc/Hz and -171 dBc/Hz without cross correlation at 1 kHz, 10 kHz, 100 kHz and 1 MHz Fourier offset frequency for a 10 GHz carrier, respectively. Moreover, since no cross correlation is necessary, RF oscillator phase noise can be directly suppressed via feedback up to 100 kHz frequency offset.

  18. A novel light tracing system with high-precision and high-sensitivity sensors setup

    Science.gov (United States)

    Lin, Chern-Sheng; Wu, Pin Yi; Tsai, Jen Min; Tseng, Yu Hung; Chen, Hsin-Hung; Hwang, Jiann-Lih

    2013-11-01

    This paper presents a novel light source tracing system, which is comprised of a light-tracing board, with four photo-sensors of different incline angles, correspondingly disposed on its four edges, which are adjustable according to the movement range of the light source in order to achieve light-tracing purposes. This system introduces the algorithm of four-edge-sensors with servo motors in each site to improve sensor's sensitivity. The measurement values of light perception can be feedback to the programmable logic controller by wireless transceiver module. After proportional-integral-derivative operation, the system can obtain the situation of light source. In a normal mode, the light source movement range is large, the range of the incline angle of the light sensors are also set to large to obtain wide detection angle. But in a locking mode, the incline angle of the light sensing plane decreases, thus, the measurement range reduces, and the sensitivity is higher.

  19. Engineered nanoconstructs for the multiplexed and sensitive detection of high-risk pathogens

    Science.gov (United States)

    Seo, Youngmin; Kim, Ji-Eun; Jeong, Yoon; Lee, Kwan Hong; Hwang, Jangsun; Hong, Jongwook; Park, Hansoo; Choi, Jonghoon

    2016-01-01

    Many countries categorize the causative agents of severe infectious diseases as high-risk pathogens. Given their extreme infectivity and potential to be used as biological weapons, a rapid and sensitive method for detection of high-risk pathogens (e.g., Bacillus anthracis, Francisella tularensis, Yersinia pestis, and Vaccinia virus) is highly desirable. Here, we report the construction of a novel detection platform comprising two units: (1) magnetic beads separately conjugated with multiple capturing antibodies against four different high-risk pathogens for simple and rapid isolation, and (2) genetically engineered apoferritin nanoparticles conjugated with multiple quantum dots and detection antibodies against four different high-risk pathogens for signal amplification. For each high-risk pathogen, we demonstrated at least 10-fold increase in sensitivity compared to traditional lateral flow devices that utilize enzyme-based detection methods. Multiplexed detection of high-risk pathogens in a sample was also successful by using the nanoconstructs harboring the dye molecules with fluorescence at different wavelengths. We ultimately envision the use of this novel nanoprobe detection platform in future applications that require highly sensitive on-site detection of high-risk pathogens.

  20. Low air exchange rate causes high indoor radon concentration in energy-efficient buildings.

    Science.gov (United States)

    Vasilyev, A V; Yarmoshenko, I V; Zhukovsky, M V

    2015-06-01

    Since 1995, requirements on energy-efficient building construction were established in Russian Building Codes. In the course of time, utilisation of such technologies became prevailing, especially in multi-storey building construction. According to the results of radon survey in buildings constructed meeting new requirements on energy efficiency, radon concentration exceeds the average level in early-constructed buildings. Preponderance of the diffusion mechanism of radon entry in modern multi-storey buildings has been experimentally established. The experimental technique of the assessment of ventilation rate in dwellings under real conditions was developed. Based on estimates of average ventilation rate, it was approved that measures to increase energy efficiency lead to reduction in ventilation rate and accumulation of higher radon concentrations indoors. Obtained ventilation rate values have to be considered as extremely low.

  1. A Highly Sensitive Refractometric Sensor Based on Cascaded SiN Microring Resonators

    Directory of Open Access Journals (Sweden)

    Daniel Pergande

    2013-10-01

    Full Text Available We investigate a highly sensitive optical sensor based on two cascaded microring resonators exploiting the Vernier effect. The architecture consists of two microrings with a slight difference in their free spectral ranges. This allows the generation of the Vernier effect for achieving ultra-high sensitivities. The sensor chip was fabricated using a silicon nitride platform and characterized with isopropanol/ethanol mixtures. A sensitivity of 0.95 nm/% was found for isopropanol concentrations in ethanol ranging from 0% to 10%. Furthermore, a collection of measurements was carried out using aqueous sodium chloride (NaCl in solutions of different concentrations, confirming a high sensitivity of 10.3 nm/% and a bulk refractive index sensitivity of 6,317 nm/RIU. A limit of detection of 3.16 ´ 10−6 RIU was determined. These preliminary results show the potential features of cascaded silicon nitride microring resonators for real-time and free-label monitoring of biomolecules for a broad range of applications.

  2. High sensitivity to punishment and low impulsivity in obsessive-compulsive patients with hoarding symptoms.

    Science.gov (United States)

    Fullana, Miquel Angel; Mataix-Cols, David; Caseras, Xavier; Alonso, Pino; Manuel Menchón, Josep; Vallejo, Julio; Torrubia, Rafael

    2004-11-30

    Recent factor-analytic studies involving over 2000 patients have reduced the symptoms of obsessive-compulsive disorder (OCD) into a few dimensions or potentially overlapping syndromes. Hoarding consistently emerged as a separate factor in all these studies. This study investigated the relationship between OCD symptom dimensions and normal personality traits in a sample of 56 OCD patients. They were administered the Sensitivity to Punishment and Sensitivity to Reward Questionnaire and the Eysenck Personality Questionnaire, derived from Gray's and Eysenck's personality models, respectively. The personality scores were correlated with previously identified symptom dimensions from the Yale-Brown Obsessive-Compulsive Scale Symptom Checklist (Y-BOCS-SC), controlling for overall illness severity. High scores on the hoarding dimension of the Y-BOCS-SC were positively correlated with scores on the Sensitivity to Punishment scale and negatively with Eysenck's Psychoticism scale. While high sensitivity to punishment is a personality feature common to many OCD patients, it is more strongly pronounced in patients with hoarding symptoms. These patients also appear to be less impulsive or novelty seeking as reflected by low scores on Eysenck's Psychoticism scale. High sensitivity to punishment and low novelty seeking in OCD hoarders might explain their poor compliance and response to conventional treatments, but this question needs to be explored further in a prospective treatment study.

  3. High-sensitivity sucrose erbium-doped fiber ring laser sensor

    Science.gov (United States)

    Khaleel, Wurood Abdulkhaleq; Al-Janabi, Abdul Hadi M.

    2017-02-01

    We investigate a high-sensitivity sucrose sensor based on a standard erbium-doped fiber ring laser incorporating a coreless fiber (CF). A single-mode-coreless-single mode (SCS) structure with a very low insertion loss has been constructed. The SCS fiber structure performed dual function as an intracavity fiber filter and/or a sensing element. The gain medium (erbium-doped fiber) is pumped by a 975-nm wavelength fiber coupled diode laser. Laser emission around 1537 nm with -2 dBm peak output power is obtained when a CF in SCS structure has a diameter of 125 μm. The 3-dB line-width of the laser is <0.14 nm, which is beneficial to high precision sensing. The sucrose concentration varied from 0% to 60%, and the relationship between the lasing wavelength and the sucrose concentration exhibited linear behavior (R2=0.996), with sensitivity of 0.16 nm/% was obtained. To improve the measurement sensitivity, the CF is etched by hydrofluoric acid. The splice joint of etched CF with SMF is a taper, which improves its sensitivity to sucrose changes. An average sensitivity of 0.57 nm/% and a high signal-to-noise ratio of 50 dB make the proposed sensor suitable for potential applications.

  4. A highly sensitive refractometric sensor based on cascaded SiN microring resonators.

    Science.gov (United States)

    Zamora, Vanessa; Lützow, Peter; Weiland, Martin; Pergande, Daniel

    2013-10-28

    We investigate a highly sensitive optical sensor based on two cascaded microring resonators exploiting the Vernier effect. The architecture consists of two microrings with a slight difference in their free spectral ranges. This allows the generation of the Vernier effect for achieving ultra-high sensitivities. The sensor chip was fabricated using a silicon nitride platform and characterized with isopropanol/ethanol mixtures. A sensitivity of 0.95 nm/% was found for isopropanol concentrations in ethanol ranging from 0% to 10%. Furthermore, a collection of measurements was carried out using aqueous sodium chloride (NaCl) in solutions of different concentrations, confirming a high sensitivity of 10.3 nm/% and a bulk refractive index sensitivity of 6,317 nm/RIU. A limit of detection of 3.16 × 10(-6) RIU was determined. These preliminary results show the potential features of cascaded silicon nitride microring resonators for real-time and free-label monitoring of biomolecules for a broad range of applications.

  5. The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome

    Directory of Open Access Journals (Sweden)

    Özlem Yiğit

    2011-11-01

    Full Text Available Objective: ACS is the life threatening causes of chest pain. The aim of this study is to detect the sensitivity and specificity of CRP, IL-6 and D-dimer and identify their role in predicting adverse cardiac events. Material and Methods: All patients describing typical chest pain were enrolled in the study. Demographic features and final diagnosis were written and serum specimens were collected. All patients were telephoned after one month to determine if there were any adverse cardiac events. Results: There were 132 patients, (94 male, 38 female. The mean age was 60.92±10.78. 55 patients were diagnosed as AMI (37 STEMI and 18 NSTEMI 60 patients as unstable angina pectoris, 15 patients as stable angina pectoris and 2 patients as non cardiac chest pain. 6 patients died in the hospital. 15 patients had adverse cardiac events (12 recurrent AMI, 2 sudden cardiac death, 1 stroke. The levels of D-dimer, CRP and IL-6 at the presentation were not predictive for adverse events. Conclusion: D-dimer, CRP and IL-6 levels were high both in ACS and stable angina. Detecting the predictive value for adverse cardiac events requires larger patient numbers and longer follow up times.

  6. Assessment of rainwater use and greywater reuse in high-rise buildings in a brownfield site.

    Science.gov (United States)

    Zhang, Yan; Grant, Andrew; Sharma, Ashok; Chen, Donghui; Chen, Liang

    2009-01-01

    This study describes the use of rainwater and greywater (originated from bathroom only) for provision of non-contact indoor and outdoor use in high-rise buildings. A brownfield development site in Box Hill suburb of Melbourne was selected as case study site for this investigation. The performance of alternative servicing options was compared with conventional water supply, stormwater and wastewater servicing. A water balance model UVQ (Urban Volume and Quality) was applied to determine storage capacities and to evaluate the percentage reduction in water supplying, stormwater run-off and wastewater disposal, as well as volumes of rainwater use and greywater reuse. In this study, the impact of variation in collection area (600 m(2) and 900 m(2)) and appliance discharge volumes was examined. A number of demand management options were also investigated. The results of this study indicate greywater reuse is more suited than rainwater use for this development because of the steady, constant supply of greywater compared to the highly fluctuating, storm-event supply of rainwater and the high population density creating comparatively large volumes of greywater.

  7. Building High-Resolution Sky Images Using the Cell/B.E.

    Directory of Open Access Journals (Sweden)

    Ana Lucia Varbanescu

    2009-01-01

    Full Text Available The performance potential of the Cell/B.E., as well as its availability, have attracted a lot of attention from various high-performance computing (HPC fields. While computation intensive kernels proved to be exceptionally well suited for running on the Cell, irregular data-intensive applications are usually considered as poor matches. In this paper, we present our complete solution for enabling such a data-intensive application to run efficiently on the Cell/B.E. processor. Specifically, we target radioastronomy data gridding and degridding, two resembling imaging filters based on convolutional resampling. Our solution is based on building a high-level application model, used to evaluate parallelization alternatives. Next, we choose the one with the best performance potential, and we gradually exploit this potential by applying platform-specific and application-specific optimizations. After several iterations, our target application shows a speed-up factor between 10 and 20 on a dual-Cell blade when compared with the original application running on a commodity machine. Given these results, and based on our empirical observations, we are able to pinpoint a set of ten guidelines for parallelizing similar applications on the Cell/B.E. Finally, we conclude the Cell/B.E. can provide high performance for data-intensive applications at the price of increased programming efforts and with a significant aid from aggressive application-specific optimizations.

  8. Towards Building High Performance Medical Image Management System for Clinical Trials.

    Science.gov (United States)

    Wang, Fusheng; Lee, Rubao; Zhang, Xiaodong; Saltz, Joel

    2011-01-01

    Medical image based biomarkers are being established for therapeutic cancer clinical trials, where image assessment is among the essential tasks. Large scale image assessment is often performed by a large group of experts by retrieving images from a centralized image repository to workstations to markup and annotate images. In such environment, it is critical to provide a high performance image management system that supports efficient concurrent image retrievals in a distributed environment. There are several major challenges: high throughput of large scale image data over the Internet from the server for multiple concurrent client users, efficient communication protocols for transporting data, and effective management of versioning of data for audit trails. We study the major bottlenecks for such a system, propose and evaluate a solution by using a hybrid image storage with solid state drives and hard disk drives, RESTful Web Services based protocols for exchanging image data, and a database based versioning scheme for efficient archive of image revision history. Our experiments show promising results of our methods, and our work provides a guideline for building enterprise level high performance medical image management systems.

  9. Detection and Analysis of High Temperature Sensitivity of TGMS Lines in Rice Using AMMI Model

    Institute of Scientific and Technical Information of China (English)

    FU Li-zhong; XUE Qing-zhong

    2004-01-01

    With the AMMI(additive main effects and multiplicative interaction)analysis model,the determination of the sensitivity to temperature among different TGMS(thermo-sensitive genic male sterile)lines was performed. To assess the genetic differences due to high temperature stress at. the fertility-sensitive stage(10- 20 d before heading),seven genotypes(six TGMS lines and the control Pei-Ai64S)were grown from May 4 at seven different stages with 10d intervals. The temperatures at. the fertility-sensitive stages involved twelve levels from < 20 to >30℃ under the regime natural conditions in Hangzhou,China. There was considerable variation in pollen fertility among genotypes in response to high temperature. Five genotypes identified as TGMS lines as their percentages of fertile pollens were lower than or close to that. of the. control except for the unstable line RTS19(V6). When the temperatures at. the fertility-sensitive stage were at Ⅰ -Ⅳ,Ⅴ-Ⅵ and Ⅶ-Ⅻ,the percentages of fertile pollens varied in the ranges of 46.46- 48.49%,19.62-22.79% and 3.49- 5.87%,respectively. The critical temperatures of sterility and fertility in the five TGMS lines were 25.1 and 23.0℃,respectively. Considering the amounts and directions of main effect and their IPCA(interaction principal components analysis),we can classify the lines and temperature levels into different groups,and describe the characteristics of genotyPe x temperature interaction,offering the information and tools for the development and utility of thermo-sensitive male sterile lines.Several TGMS rice lines with their reproductive sensitivity to high temperature that can be screened using the AMMI model may add valuable germplasm to the breeding program of hybrid rice.

  10. Modeling Methodology of Progressive Collapse by the Example of Real High-Rise Buildings

    OpenAIRE

    Mariya Barabash

    2014-01-01

    The purpose of the research was to find out several ways to design real buildings with protective measures against progressive collapse. There are no uniform guidelines for choosing the type of finite element able to provide the necessary accuracy of the calculation model taking into account all the main factors affecting the strength and stability of the building. Therefore it is required to develop numerical methods for calculation on progressive collapse of buildings bearing structural ele...

  11. Study on prevention of spread of vertical fire along finishing materials for external wall of high-rise buildings

    Directory of Open Access Journals (Sweden)

    Yoo Yong Ho

    2013-11-01

    Full Text Available Although there are laws in the Korea Building Act relating to exterior finishing materials, fireproof structures and fire-stop of curtain wall structures, the standards relating to and test methods on securing detailed fire safety functions for exterior materials of all buildings including high-rise buildings have not been prepared. This is due to the fact that test methods and standards to quantitatively evaluate the vertical fire spread of the exterior material of buildings do not exist. In addition, while semi non-combustible materials or non-combustible materials are required to be used to prevent fire spread in buildings which exceed 30-stories, it is necessary to review the standards and regulations in cases where fire blocking systems, capable of preventing the vertical fire spread within the curtain wall, are installed to consider permitting the utilization of fire retardant material following an assessment of the construction characteristics of high-rise buildings. The functional evaluation standards and test methods on the vertical fire spread introduced in this study will be a more effective method for performing evaluations to prevent fire spread compared to the currently utilized method of performing small scale tests.

  12. Mesoporous structured MIPs@CDs fluorescence sensor for highly sensitive detection of TNT.

    Science.gov (United States)

    Xu, Shoufang; Lu, Hongzhi

    2016-11-15

    A facile strategy was developed to prepare mesoporous structured molecularly imprinted polymers capped carbon dots (M-MIPs@CDs) fluorescence sensor for highly sensitive and selective determination of TNT. The strategy using amino-CDs directly as "functional monomer" for imprinting simplify the imprinting process and provide well recognition sites accessibility. The as-prepared M-MIPs@CDs sensor, using periodic mesoporous silica as imprinting matrix, and amino-CDs directly as "functional monomer", exhibited excellent selectivity and sensitivity toward TNT with detection limit of 17nM. The recycling process was sustainable for 10 times without obvious efficiency decrease. The feasibility of the developed method in real samples was successfully evaluated through the analysis of TNT in soil and water samples with satisfactory recoveries of 88.6-95.7%. The method proposed in this work was proved to be a convenient and practical way to prepare high sensitive and selective fluorescence MIPs@CDs sensors.

  13. High Excitation Transfer Efficiency from Energy Relay Dyes in Dye-Sensitized Solar Cells

    KAUST Repository

    Hardin, Brian E.

    2010-08-11

    The energy relay dye, 4-(Dicyanomethylene)-2-methyl-6-(4- dimethylaminostyryl)-4H-pyran (DCM), was used with a near-infrared sensitizing dye, TT1, to increase the overall power conversion efficiency of a dye-sensitized solar cell (DSC) from 3.5% to 4.5%. The unattached DCM dyes exhibit an average excitation transfer efficiency (EÌ?TE) of 96% inside TT1-covered, mesostructured TiO2 films. Further performance increases were limited by the solubility of DCM in an acetonitrile based electrolyte. This demonstration shows that energy relay dyes can be efficiently implemented in optimized dye-sensitized solar cells, but also highlights the need to design highly soluble energy relay dyes with high molar extinction coefficients. © 2010 American Chemical Society.

  14. Surface plasmon resonance hydrogen sensor based on metallic grating with high sensitivity.

    Science.gov (United States)

    Lin, Kaiqun; Lu, Yonghua; Chen, Junxue; Zheng, Rongsheng; Wang, Pei; Ming, Hai

    2008-11-10

    High sensitivity is obtained at larger resonant incident angle if negative diffraction order of metallic grating is used to excite the surface plasmon. A highly sensitive grating-based surface plasmon resonance (SPR) sensor is designed for the hydrogen detection. A thin palladium (Pd) film deposited on the grating surface is used as transducer. The influences of grating period and the thickness of Pd on the performance of sensor are investigated using rigorous coupled-wave analysis (RCWA) method. The sensitivity as well as the width of the SPR curves and reflective amplitude is considered simultaneously for designing the grating-based SPR hydrogen sensor, and a set of optimized structural parameters is presented. The performance of grating-based SPR sensor is also compared with that of conventional prism-based SPR sensor.

  15. Elucidation of high sensitivity of δ-HMX: New insight from first principles simulations

    Science.gov (United States)

    Kuklja, Maija M.; Tsyshevsky, Roman V.; Sharia, Onise

    2017-01-01

    Understanding of a significant difference in sensitivities of β and δ phases of cyclotetramethylene-tetranitramine (HMX) has been long one of the challenges in the field of high energy density materials. Despite many experimental and theoretical efforts to explain the high sensitivity of the δ phase, convincing reasons behind the HMX behavior remained unclear. We established that the presence of a polar surface in δ-HMX has fundamental implications for stability and overall chemical behavior of the material. A comparative quantum-chemical analysis of decomposition mechanisms in polar δ-HMX and nonpolar β-HMX discovered a considerable difference in dominating dissociation reactions, activation barriers, and reaction rates. The polarization-induced charge transfer offered a logical explanation for different sensitivity of β-HMX and δ-HMX polymorphs to detonation initiation. Our conclusions also removed long-standing contradictions and explained a large range of experimental data on thermal decomposition of HMX.

  16. Food intake and energy expenditure are increased in high-fat-sensitive but not in high-carbohydrate-sensitive obesity-prone rats.

    Science.gov (United States)

    Azzout-Marniche, Dalila; Chaumontet, Catherine; Nadkarni, Nachiket A; Piedcoq, Julien; Fromentin, Gilles; Tomé, Daniel; Even, Patrick C

    2014-08-01

    Obesity-prone (OP) rodents are used as models of human obesity predisposition. The goal of the present study was to identify preexisting defects in energy expenditure components in OP rats. Two studies were performed. In the first one, male Wistar rats (n = 48) were fed a high-carbohydrate diet (HCD) for 3 wk and then a high-fat diet (HFD) for the next 3 wk. This study showed that adiposity gain under HCD was 2.9-fold larger in carbohydrate-sensitive (CS) than in carbohydrate-resistant (CR) rats, confirming the concept of "carbohydrate-sensitive" rats. Energy expenditure (EE), respiratory quotient (RQ), caloric intake (CI), and locomotor activity measured during HFD identified no differences in EE and RQ between fat-resistant (FR) and fat-sensitive (FS) rats, and indicated that obesity developed in FS rats only as the result of a larger CI not fully compensated by a parallel increase in EE. A specific pattern of spontaneous activity, characterized by reduced activity burst intensity, was identified in FS rats but not in CS ones. This mirrors a previous observation that under HCD, CS but not FS rats, exhibited bursts of activity of reduced intensity. In a second study, rats were fed a HFD for 3 wk, and the components of energy expenditure were examined by indirect calorimetry in 10 FR and 10 FS rats. This study confirmed that a low basal EE, reduced thermic effect of feeding, defective postprandial energy partitioning, or a defective substrate utilization by the working muscle are not involved in the FS phenotype. Copyright © 2014 the American Physiological Society.

  17. Evaluation of Stiffness Changes in a High-Rise Building by Measurements of Lateral Displacements Using GPS Technology

    Directory of Open Access Journals (Sweden)

    Se Woon Choi

    2013-11-01

    Full Text Available The outrigger truss system is one of the most frequently used lateral load resisting structural systems. However, little research has been reported on the effect of installation of outrigger trusses on improvement of lateral stiffness of a high-rise building through full-scale measurements. In this paper, stiffness changes of a high-rise building due to installation of outrigger trusses have been evaluated by measuring lateral displacements using a global positioning system (GPS. To confirm the error range of the GPS measurement system used in the full-scale measurement tests, the GPS displacement monitoring system is investigated through a free vibration test of the experimental model. Then, for the evaluation of lateral stiffness of a high-rise building under construction, the GPS displacement monitoring system is applied to measurements of lateral displacements of a 66-story high-rise building before and after installation of outrigger truss. The stiffness improvement of the building before and after the installation is confirmed through the changes of the natural frequencies and the ratios of the base shear forces to the roof displacements.

  18. High IgE sensitization to maize and rice pollen in the highlands of Madagascar

    Science.gov (United States)

    Ramavovololona; Sénéchal, Hélène; Andrianarisoa, Ange; Rakotoarimanana, Vololona; Godfrin, Dominique; Peltre, Gabriel; Poncet, Pascal; Sutra, Jean-Pierre

    2014-01-01

    Introduction Maize and rice are two crops constituting the main food supply in many under-developed and developing countries. Despite the large area devoted to the culture, the sensitization to the pollen from these plants is reported to be low and often considered as an occupational allergy. Methods Sixty five Malagasy pollen allergic patients were clinically and immunochemically investigated with regard to maize and rice pollen allergens. Pollen extracts were electrophoretically separated in 1 and 2 dimensions and IgE and IgG reactivities detected upon immunoblotting. Results When exploring the sensitization profile of Malagasy allergic patients to maize and rice pollen, it appears that a high proportion of these patients consulting during grass pollinating season were sensitized to both pollen as revealed by skin prick testing (62 vs. 59%) and IgE immunoblotting (85 vs. 40%). Several clinically relevant allergens were recognized by patients’ serum IgE in maize and rice pollen extracts. Conclusion The high levels of maize and rice pollen sensitization should be related, in this tropical region, to a specific environmental exposure including i) a proximity of the population to the allergenic sources and ii) a putative exacerbating effect of a highly polluted urban atmosphere on pollen allergenicity. Cross-reactivities between wild and cultivated grasses and also between rice and maize pollen are involved as well as some specific maize sensitizations. The presence of dense urban and peri-urban agriculture, in various African regions and worldwide, could be a high environmental risk factor for people sensitive to maize pollen. PMID:25870739

  19. Niacin Skin Sensitivity Is Increased in Adolescents at Ultra-High Risk for Psychosis.

    Directory of Open Access Journals (Sweden)

    Gregor E Berger

    Full Text Available Most studies provide evidence that the skin flush response to nicotinic acid (niacin stimulation is impaired in schizophrenia. However, only little is known about niacin sensitivity in the ultra-high risk (UHR phase of psychotic disorders.We compared visual ratings of niacin sensitivity between adolescents at UHR for psychosis according to the one year transition outcome (UHR-T n = 11; UHR-NT n = 55 with healthy controls (HC n = 25 and first episode schizophrenia patients (FEP n = 25 treated with atypical antipsychotics.Contrary to our hypothesis niacin sensitivity of the entire UHR group was not attenuated, but significantly increased compared to the HC group, whereas no difference could be found between the UHR-T and UHR-NT groups. As expected, niacin sensitivity of FEP was attenuated compared to HC group. In UHR individuals niacin sensitivity was inversely correlated with omega-6 and -9 fatty acids (FA, but positively correlated with phospholipase A2 (inPLA2 activity, a marker of membrane lipid repair/remodelling.Increased niacin sensitivity in UHR states likely indicates an impaired balance of eicosanoids and omega-6/-9 FA at a membrane level. Our findings suggest that the emergence of psychosis is associated with an increased mobilisation of eicosanoids prior to the transition to psychosis possibly reflecting a "pro-inflammatory state", whereas thereafter eicosanoid mobilisation seems to be attenuated. Potential treatment implications for the UHR state should be further investigated.

  20. Protein A immunoadsorption combined with rituximab in highly sensitized kidney transplant recipients

    Institute of Scientific and Technical Information of China (English)

    YIN Hang; HU Xiao-peng; LI Xiao-bei; LIU Hang; WANG Wei; REN Liang; WANG Yong; ZHANG Xiao-dong

    2009-01-01

    Background The number of highly sensitized patients is rising, and sensitization can lead to renal transplant failure.The present study aimed to investigate the safety and efficacy of protein A immunoadsorption combined with rituximab (RTX) in highly sensitized recipients of kidney transplants.Methods Seven highly sensitized recipients of living-related renal transplants (4 men and 3 women, mean aged 42.5 years old (range 33-51)) were pretreated with this combination. Human leukocyte antigen (HLA) mismatch number was 2-5. Panel reactive antibody (PRA) of class 1 was high in 2 cases and that of class Ⅱ was high in 1 case. All patients were pretreated with immunoadsorption 2-10 times. Immunoglobulin and PRA changes were monitored before and after absorption. The operation was conducted when PRA or immunoglobulin levels were at or below normal levels.Immunosuppressive drugs were provided 3-5 days before the operation, and one dose of RTX (375 mg/m~2) was infused with polyclonal antibody on the day of operation. Postoperative creatinine (Cr), creatinine clearance rate (Ccr), PRA ratio,and immunoglobulin changes were monitored.Results All 7 patients had good recovery without delayed graft function. Acute rejection occurred in 3 cases at postoperative days 8, 10, and 14, respectively. The Banff 07 biopsy grades were la in 1 case and lla C4d0 in 2 cases.Successful reversion was achieved after giving methylprednisolone or antithymocyte immunoglobulin + cyclophosphamide. All patients were discharged with normal renal function, mean class 1 PRA was 14% and mean class Ⅱ PRA was 35%. PRA was completely negative in 3 cases.Conclusion Protein A immunoadsorption combined with RTX can safely reduce the occurrence of humoral rejection in highly sensitized renal transplant recipients.