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Sample records for buc xa gamma

  1. Overview on the BUC activities at the IAEA

    International Nuclear Information System (INIS)

    Full text: Due to the worldwide interest and broad applicability of BUC for spent fuel management, the International Atomic Energy Agency (IAEA) has taken an active interest in the subject. The IAEA role has been one of an observer and disseminator of appropriate information. In 1997, the International Atomic Energy Agency (IAEA) started a task to monitor the implementation of BUC in spent fuel management systems, to provide a forum to exchange information, to discuss the matter and to gather and disseminate information on the status of national practices of BUC implementation in the Member States. The task addressed current and future aspects of BUC. In October 1997, the IAEA organized an advisory group meeting (AGM) to examine and report on the status of BUC for storage, transport, reprocessing, and disposal of PWR, BWR, WWER, RBMK and MOX spent fuel. Since the proceedings of the AGM were published in April 1998 (IAEA-TECDOC-1013), significant developments have served to advance the use of BUC throughout the world. Experts from countries with nuclear programmes that range from very small to very large have made important contributions. The use of BUC has progressed along the lines of greatest need. In the following years, several consultancies were held to monitor the progress in BUC implementation. (July and December 1998, July 1999 and July 2001). The results of these meetings were published in three Working Materials. A technical committee Meeting (TCM) on the Evaluation and Review of the Implementation of BUC in Spent Fuel Management Systems was held in July 2000 in Vienna with 35 experts from 17 countries and 2 international organizations. The purpose of this TCM was to survey the progress and status of international activities related to the use of BUC for spent fuel applications. The current BUC applications status and the BUC level implemented in each application were collected and published in Tables. Conclusions of the TCM. During the closing session of

  2. Expressional and Biochemical Characterization of Rice Disease Resistance Gene Xa3/Xa26 Family

    Institute of Scientific and Technical Information of China (English)

    Songjie Xu; Yinglong Cao; Xianghua Li; Shiping Wang

    2007-01-01

    The rice (Oryza sativa L.) Xa3/Xa26 gene, conferring race-specific resistance to bacterial blight disease and encoding a leucine-rich repeat (LRR) receptor kinase-like protein, belongs to a multigene family consisting of tandem clustered homologous genes, colocalizing with several uncharacterized genes for resistance to bacterial blight or fungal blast. To provide more information on the expressional and biochemical characteristics of the Xa3/Xa26 family, we analyzed the family members. Four Xa3/Xa26 family members in the indica rice variety Teqing, which carries a bacterial blight resistance gene with a chromosomal location tightly linked to Xa3/Xa26, and five Xa3/Xa26 family members in the japonica rice variety Nipponbare, which carries at least one uncharacterized blast resistance gene, were constitutively expressed in leaf tissue. The result suggests that some of the family members may be candidates of these uncharacterized resistance genes. At least five putative N-glycosylation sites in the LRR domain of XA3/XA26 protein are not glycosylated. The XA3/XA26 and its family members MRKa and MRKc all possess the consensus sequences of paired cysteines, which putatively function in dimerization of the receptor proteins for signal transduction, immediately before the first LRR and immediately after the last LRR. However, no homo-dimer between the XA3/XA26 molecules or hetero-dimer between XA3/XA26 and MRKa or MRKc were formed, indicating that XA3/XA26 protein might function either as a monomer or a hetero-dimer formed with other protein outside of the XA3/XA26 family. These results provide valuable information for further extensive investigation into this multiple protein family.

  3. Clinical Scenarios for Discordant Anti-Xa

    OpenAIRE

    Jesus Vera-Aguilera; Hindi Yousef; Diego Beltran-Melgarejo; Teng Hugh Teng; Ramos Jan; Mary Mok; Carlos Vera-Aguilera; Eduardo Moreno-Aguilera

    2016-01-01

    Anti-Xa test measures the activity of heparin against the activity of activated coagulation factor X; significant variability of anti-Xa levels in common clinical scenarios has been observed. Objective. To review the most common clinical settings in which anti-Xa results can be bias. Evidence Review. Guidelines and current literature search: we used PubMed, Medline, Embase, and MEDION, from 2000 to October 2013. Results. Anti-Xa test is widely used; however the assay underestimates heparin co...

  4. Clinical Scenarios for Discordant Anti-Xa

    Science.gov (United States)

    Vera-Aguilera, Jesus; Yousef, Hindi; Beltran-Melgarejo, Diego; Teng, Teng Hugh; Jan, Ramos; Mok, Mary; Vera-Aguilera, Carlos; Moreno-Aguilera, Eduardo

    2016-01-01

    Anti-Xa test measures the activity of heparin against the activity of activated coagulation factor X; significant variability of anti-Xa levels in common clinical scenarios has been observed. Objective. To review the most common clinical settings in which anti-Xa results can be bias. Evidence Review. Guidelines and current literature search: we used PubMed, Medline, Embase, and MEDION, from 2000 to October 2013. Results. Anti-Xa test is widely used; however the assay underestimates heparin concentration in the presence of significant AT deficiency, pregnancy, end stage renal disease, and postthrombolysis and in patients with hyperbilirubinemia; limited published data evaluating the safety and effectiveness of anti-Xa assays for managing UH therapy is available. Conclusions and Relevance. To our knowledge this is the first paper that summarizes the most common causes in which this assay can be affected, several “day to day” clinical scenarios can modify the outcomes, and we concur that these rarely recognized scenarios can be affected by negative outcomes in the daily practice. PMID:27293440

  5. Clinical Scenarios for Discordant Anti-Xa

    Directory of Open Access Journals (Sweden)

    Jesus Vera-Aguilera

    2016-01-01

    Full Text Available Anti-Xa test measures the activity of heparin against the activity of activated coagulation factor X; significant variability of anti-Xa levels in common clinical scenarios has been observed. Objective. To review the most common clinical settings in which anti-Xa results can be bias. Evidence Review. Guidelines and current literature search: we used PubMed, Medline, Embase, and MEDION, from 2000 to October 2013. Results. Anti-Xa test is widely used; however the assay underestimates heparin concentration in the presence of significant AT deficiency, pregnancy, end stage renal disease, and postthrombolysis and in patients with hyperbilirubinemia; limited published data evaluating the safety and effectiveness of anti-Xa assays for managing UH therapy is available. Conclusions and Relevance. To our knowledge this is the first paper that summarizes the most common causes in which this assay can be affected, several “day to day” clinical scenarios can modify the outcomes, and we concur that these rarely recognized scenarios can be affected by negative outcomes in the daily practice.

  6. La poesía bucólica en época de Nerón : lectura virgiliana, ideología senequiana y propaganda imperial

    OpenAIRE

    Ruiz Arzalluz, Iñigo

    1993-01-01

    [ES] Durante los pocos años del gobierno de Nerón la poesía bucólica latina experimenta un auge anormal y desarrolla una función propagandística particularmente clara. En este artículo se trata de reconstruir, a partir de textos que hasta ahora no se habían implicado debidamente en la cuestión (cuarta égloga de Virgilio, Apocolocyntosis de Séneca, etc.), las motivaciones inmediatas de este resurgir del género: la poesía bucólica de la época responde en parte a una invitación expresa que Sénec...

  7. The new factor Xa inhibitor: Apixaban

    Directory of Open Access Journals (Sweden)

    Sangeeta Bhanwra

    2014-01-01

    Full Text Available Cardiovascular diseases are still the most important cause of morbidity and mortality worldwide and anti-thrombotic treatment is widely used as a result. The currently used drugs include heparin and its derivatives, vitamin K antagonists, though efficacious, have their own set of limitations like unpredictable pharmacokinetic profile, parenteral route (with heparin and its derivatives only, narrow therapeutic window, and constant laboratory monitoring for their efficacy and safety. This lead to the development of novel factor Xa inhibitors which could be given orally, have predictable dose response relationship and are associated with lesser hemorrhagic complications. They include rivaroxaban, apixaban, and edoxaban among others. Apixaban has currently been approved for use in patients undergoing total knee or hip replacement surgery and to prevent stroke in patients with atrial fibrillation. Many trials are ongoing for apixaban to firmly establish its place in future, among the anti-thrombotic drugs.

  8. Bucólico: aplicación computacional para el análisis de textos. (hacia un análisis de rasgos de la informatividad

    Directory of Open Access Journals (Sweden)

    Giovanni Parodi S.

    2004-01-01

    Full Text Available La aplicación computacional BUCÓLICO (buscador de concordancias Lingüísticas en Corpus permite organizar tres corpora lingüísticos previamente procesados y etiquetados morfológicamente o analizar otros corpora, no etiquetados computacionalmente, a través del procesamiento de lenguaje natural. Desde un enfoque metodológico de la lingüística de Hábeas Computacional, se indaga, comparativamente a partir de los datos obtenidos con bucólico, en la ocurrencia de cuatro estructuras lingüísticas de alta densidad, compactación o integración informacionalBucólico (Buscador de Concordancias Lingüísticas en Corpus is a computational tool which is helps organize three linguistic corpora, previously processed and automatically tagged morfosintacically, and it analices other linguistic corpora, not computationally tagged though the precessing of natural language. The methodological principles of the modern computational corpus linguistics reserches about the occurrence of four linguistic features, typically associated with high density, integration, compactness and informational load

  9. Transcriptional Characteristics of Xa21-mediated Defense Responses in Rice

    Institute of Scientific and Technical Information of China (English)

    Qiang Gan; Hui Bai; Xianfeng Zhao; Yong Tao; Haipan Zeng; Yuning Han; Wenyuan Song; Lihuang Zhu; Guozhen Liu

    2011-01-01

    Bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo), is the most destructive bacterial disease of rice. The cloned rice gene Xa21 confers resistance to a broad spectrum of Xoo races. To identify genes involved in Xa21-mediated immunity, a whole-genome oligonucleotide microarray of rice was used to profile the expression of rice genes between incompatible interactions and mock treatments at 0, 4, 8, 24, 72 and 120 h post inoculation (hpi) or between incompatible and compatible interactions at 4 hpi, respectively. A total of 441 differentially expressed genes, designated as XDGs (Xa21 mediated differentially expressed genes), were identified. Based on their functional annotations, the XDGs were assigned to 14 categories, including defense-related, signaling, transcriptional regulators. Most of the defense-related genes belonged to the pathogenesis-related gene family, which was induced dramatically at 72 and 120 hpi. Interestingly, most signaling and transcriptional regulator genes were downregulated at 4 and 8 hpi, suggesting that negative regulation of cellular signaling may play a role in the Xa21-mediated defense response. Comparison of expression profiles between Xa21- and other R gene-mediated defense systems revealed interesting common responses. Representative XDGs with supporting evidences were also discussed.

  10. Marker-aided Incorporation of Xa38, a Novel Bacterial Blight Resistance Gene, in PB1121 and Comparison of its Resistance Spectrum with xa13 + Xa21.

    Science.gov (United States)

    Ellur, Ranjith K; Khanna, Apurva; S, Gopala Krishnan; Bhowmick, Prolay K; Vinod, K K; Nagarajan, M; Mondal, Kalyan K; Singh, Nagendra K; Singh, Kuldeep; Prabhu, Kumble Vinod; Singh, Ashok K

    2016-01-01

    Basmati rice is preferred internationally because of its appealing taste, mouth feel and aroma. Pusa Basmati 1121 (PB1121) is a widely grown variety known for its excellent grain and cooking quality in the international and domestic market. It contributes approximately USD 3 billion to India's forex earning annually by being the most traded variety. However, PB1121 is highly susceptible to bacterial blight (BB) disease. A novel BB resistance gene Xa38 was incorporated in PB1121 from donor parent PR114-Xa38 using a modified marker-assisted backcross breeding (MABB) scheme. Phenotypic selection prior to background selection was instrumental in identifying the novel recombinants with maximum recovery of recurrent parent phenome. The strategy was effective in delimiting the linkage drag to <0.5 mb upstream and <1.9 mb downstream of Xa38 with recurrent parent genome recovery upto 96.9% in the developed NILs. The NILs of PB1121 carrying Xa38 were compared with PB1121 NILs carrying xa13 + Xa21 (developed earlier in our lab) for their resistance to BB. Both NILs showed resistance against the Xoo races 1, 2, 3 and 6. Additionally, Xa38 also resisted Xoo race 5 to which xa13 + Xa21 was susceptible. The PB1121 NILs carrying Xa38 gene will provide effective control of BB in the Basmati growing region. PMID:27403778

  11. Evaluation of a Heparin-Calibrated Antifactor Xa Assay for Measuring the Anticoagulant Effect of Oral Direct Xa Inhibitors.

    Science.gov (United States)

    Beyer, Jacob; Trujillo, Toby; Fisher, Sheila; Ko, Ann; Lind, Stuart E; Kiser, Tyree H

    2016-07-01

    The introduction of oral direct anti-Xa anticoagulants apixaban and rivaroxaban has significantly impacted the treatment and prevention of thromboembolic disease. Clinical scenarios exist in which a quantitative assessment for degree of anticoagulation due to these agents would aid management. The purpose of this work was to evaluate the chromogenic antifactor Xa assay calibrated with heparin standards at our institution for assessment of intensity of anticoagulation with rivaroxaban or apixaban in addition to its current use for unfractionated heparin or low-molecular-weight heparin. We also aimed to propose expected steady state peak and trough antifactor Xa activities for these agents based upon dosing regimens approved for nonvalvular atrial fibrillation. Antifactor Xa activity correlated very strongly with apixaban and rivaroxaban concentration in both spiked samples and treated patient plasma samples (r (2) = .99, P < .001). This correlation was observed over a broad range (20-500 ng/mL) of drug concentrations, as sample dilution with pooled normal plasma significantly extended the range of quantitative assessment. Based on drug concentrations previously published in pharmacokinetic studies, the expected steady state peak and trough antifactor Xa activity ranges for apixaban are 1.80 to 2.20 IU/mL and 0.70 to 1.10 IU/mL, respectively. For rivaroxaban, these ranges are 3.80 to 6.20 IU/mL and 0.60 to 1.00 IU/mL, respectively. In conclusion, our findings demonstrate that heparin-calibrated antifactor Xa activity correlates strongly with apixaban and rivaroxaban concentration. The dilution of samples allowed for this correlation to be extended over the majority of on-therapy drug concentrations. PMID:26842561

  12. Lyso-Sulfatide Binds Factor Xa and Inhibits Thrombin Generation by the Prothrombinase Complex.

    Directory of Open Access Journals (Sweden)

    Subramanian Yegneswaran

    Full Text Available Blood coagulation reactions are strongly influenced by phospholipids, but little is known about the influence of sphingolipids on coagulation mechanisms. Lysosulfatide (lyso-SF (sulfogalactosyl sphingosine prolonged factor Xa (fXa 1-stage plasma clotting assays, showing it had robust anticoagulant activity. In studies using purified clotting factors, lyso-SF inhibited >90% of prothrombin (II activation for reaction mixtures containing fXa/factor Va (fVa/II, and also inhibited II activation generation by fXa/ phospholipids and by Gla-domainless-fXa/fVa/phospholipids. When lyso-SF analogs were tested, results showed that N-acetyl-sulfatide was not anticoagulant, implying that the free amine group was essential for the anticoagulant effects of lyso-SF. Lyso-SF did not inhibit fXa enzymatic hydrolysis of small peptide substrates, showing it did not directly inhibit the fXa activity. In surface plasmon resonance studies, lyso-SF bound to immobilized inactivated fXa as well as inactivated Gla-domainless-fXa. Confirming this lyso-SF:fXa interaction, fluorescence studies showed that fluorescently-labeled-fXa in solution bound to lyso-SF. Thus, lyso-SF is an anticoagulant lipid that inhibits fXa when this enzyme is bound to either phospholipids or to fVa. Mechanisms for inhibition of procoagulant activity are likely to involve lyso-SF binding to fXa domain(s that are distinct from the fXa Gla domain. This suggests that certain sphingolipids, including lyso-SF and some of its analogs, may down-regulate fXa activity without inhibiting the enzyme's active site or binding to the fXa Gla domain.

  13. Blood coagulation factor Xa as an emerging drug target

    NARCIS (Netherlands)

    K. Borensztajn; C.A. Spek

    2011-01-01

    Introduction: Factor (F) Xa is well-known as an important player in the coagulation cascade responsible for thrombin generation. More recently, FXa emerged as an essential player in cell biology via activation of proteaseactivated receptors (PAR)-1 and -2. This pleiotropic role of FXa forms the basi

  14. Data of evolutionary structure change: 1C4XA-2OG1B [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1C4XA-2OG1B 1C4X 2OG1 A B ---TVEIIEKRFPSGT---LASHALVAGDPQSPAVVLLH...EEEEEEE HHHHHHHHHHHHH 0 1C4X... A 1C4XA FPSGT---LASHA ...645107269287 4.700198173522949 1 1C4X... A 1C4XA

  15. Superfund Record of Decision (EPA Region 2): Kin-Buc Landfill, Edison Township, Middlesex County, NJ. (Second remedial action), September 1992. Final report

    International Nuclear Information System (INIS)

    The 200-acre Kin-Buc Landfill consists of several inactive disposal areas and is located in Edison Township, Middlesex County, New Jersey. Land use in the area is predominantly industrial and commercial, with some residences within 2 miles north of the site. No drinking water supply wells are located within a 2-mile radius of the site. As a result of an oil spill in 1976, EPA conducted an investigation of the property. In 1980, clean-up activities were initiated under the Clean Water Act and included removal, treatment, and disposal of leachate and drummed waste. The ROD addresses a final remedy for OU2 consisting of the sediment and groundwater in the Edmonds Creek wetlands area, Mill Brook/Martins Creek, Mound B, and the low-lying area. The primary contaminants of concern affecting the sediment and ground water are VOCs, including benzene and xylenes; other organics, including PAHs, PCBs, and pesticides; and metals, including arsenic and lead. The selected remedy for the site are included

  16. Effects of Water Soluble Phosphotidylserine on Bovine Factor Xa: Functional and Structural Changes Plus Dimerization

    OpenAIRE

    Majumder, Rinku; Wang, Jianfang; Lentz, Barry R.

    2003-01-01

    Previous work has shown that two molecules of a soluble form of phosphatidylserine, C6PS, bind to human and bovine factor Xa. Activity measurements along with the fluorescence of active-site-labeled human factor Xa showed that two linked sites specifically regulate the active site conformation and proteolytic activity of the human enzyme. These results imply, but cannot demonstrate, a C6PS-induced factor Xa conformational change. The purpose of this paper is to extend these observations to bo...

  17. A comparative approach expands the protein-protein interaction node of the immune receptor XA21 in wheat and rice

    OpenAIRE

    Yang, Baoju; Ruan, Randy; Cantu, Dario; Wang, Xiaodong; Ji, Wanquan; Ronald, Pamela C; Dubcovsky, Jorge

    2013-01-01

    The rice (Oryza sativa) OsXA21 receptor kinase is a well-studied immune receptor that initiates a signal transduction pathway leading to resistance to Xanthomonas oryzae pv. oryzae. Two homologs of OsXA21 were identified in wheat (Triticum aestivum): TaXA21-like1 located in a syntenic region with OsXA21, and TaXA21-like2 located in a non-syntenic region. Proteins encoded by these two wheat genes interact with four wheat orthologs of known OsXA21 interactors. In this study, we screened a wheat...

  18. Evaluation of Factor Xa-Specific Chromogenic Substrate Assays and the Determination of Pharmacokinetics of Fondaparinux.

    Science.gov (United States)

    Yuri, Maiko; Tabe, Yoko; Tsuchiya, Koji; Sadatsuki, Ryo; Aoki, Jun; Horii, Takashi; Iba, Toshiaki; Ohsaka, Akimichi

    2016-07-01

    Fondaparinux (FPX), a synthesized factor Xa inhibitor, is one of the most popular anticoagulants for the prevention of postoperative venous thromboembolism (VTE). Although routine monitoring is not required, the bleeding adverse events cannot be neglected, and the measurement of anti-Xa activity is expected to be monitored. The primary purpose of this study is to evaluate the performances of 2 chromogenic assays for the detection of anti-Xa activity. Furthermore, the pharmacokinetics of FPX was examined using chromogenic assays. Anti-Xa activity was measured using 2 FPX-based chromogenic substrates (S2222 and STA-Liquid Anti-Xa). The reproducibility, detection limits, linearity, and correlations between the substrates were examined using normal plasma doped with low and high concentrations of FPX formulation. In addition, anti-Xa activity in 235 clinical samples from 164 cases treated was measured, and the pharmacokinetics of FPX was evaluated. Both of the tested substrates were capable of accurately measuring the anti-Xa activity of FPX, with a lower limit of 0.05 μg/mL and a coefficient of variation of less than 10%. The repeated administration of FPX induced a gradual but significant increase in the anti-Xa activity, which was negatively correlated with body weight and estimated glomerular filtration rate. No significant correlation between the anti-Xa activity and the occurrence of postoperative VTE or bleeding event was observed. Anti-Xa activity can be successfully determined using 2 chromogenic assays and automated biochemical analyzers. The clinical significance of anti-Xa activity monitoring should be examined in the future study. PMID:26177660

  19. Mutation of the rice XA21 predicted nuclear localization sequence does not affect resistance to Xanthomonas oryzae pv. oryzae

    Science.gov (United States)

    Ho, Yuen Ting

    2016-01-01

    Background The rice receptor kinase XA21 confers robust resistance to the bacterial pathogen Xanthomonas oryzaepv. oryzae(Xoo). We previously reported that XA21 is cleaved in transgenic plants overexpressing XA21 with a GFP tag (Ubi-XA21-GFP) and that the released C-terminal domain is localized to the nucleus. XA21 carries a predicted nuclear localization sequence (NLS) that directs the C-terminal domain to the nucleus in transient assays, whereas alanine substitutions in the NLS disrupt the nuclear localization. Methods To determine if the predicted NLS is required for XA21-mediated immunity in planta, we generated transgenic plants overexpressing an XA21 variant carrying the NLS with the same alanine substitutions (Ubi-XA21nls-GFP). Results Ubi-XA21nls-GFP plants displayed slightly longer lesion lengths, higher Xoobacterial populations after inoculation and lower levels of reactive oxygen species production compared with the Ubi-XA21-GFP control plants. However, the Ubi-XA21nls-GFP plants express lower levels of protein than that observed in Ubi-XA21-GFP. Discussion These results demonstrate that the predicted NLS is not required for XA21-mediated immunity.

  20. [Roles of coagulation pathway and factor Xa in chronic kidney disease (CKD)].

    Science.gov (United States)

    Ono, Takahiko

    2012-01-01

    Considering that fibrin deposition is observed in glomerulonephritis as well as in diabetic nephropathy, we performed studies to clarify the roles of the coagulation pathway and the active type of coagulation factor X (factor Xa) in the development of chronic kidney disease (CKD) using animal models. Factor Xa activates various cell types through protease-activated receptor 2 (PAR2). Several in vitro studies have demonstrated that PAR2 can mediate factor Xa signaling, but not thrombin signaling. Coagulation processes proceed together with the extracellular matrix (ECM) accumulation through factor V expression in rat Thy-1 nephritis. DX-9065a, a factor Xa inhibitor, suppresses this type of glomerulonephritis. The factor Xa inhibitor danaparoid ameliorated proteinuria, cellular proliferation, and fibrin deposition in lipopolysaccharide (LPS)-triggered activation of High IgA (HIGA) strain of ddY mice. Another factor Xa inhibitor, fondaparinux, suppressed urinary protein, glomerular hypertrophy, and connective tissue growth factor (CTGF), and ECM protein deposition together with angiogenesis in diabetic db/db mice. Finally, in the model of peritoneal fibrosis, fondaparinux treatment decreased the thickness of submesothelial fibrotic tissue and angiogenesis. In consideration of the results to potential human therapy, factor Xa regulation may be promising for the treatment of the aggravation in glomerulonephritis and of the early phase of diabetic nephropathy. In the near future, novel factor Xa inhibitors with the characteristics of oral administration and biliary elimination may appear in the clinical use for treatment of cardiovascular diseases. PMID:22465921

  1. Purification of a Ni sup 2+ -binding protein, pNiXa, from Xenopus ovary

    Energy Technology Data Exchange (ETDEWEB)

    Beck, B.L.; Makowski, G.S.; Nomoto, S.; Sunderman, F.W. (Univ. of Connecticut, Farmington (United States))

    1991-03-11

    Previous research on nickel-induced teratogenesis in Xenopus laevis identified several Ni{sup 2+}-binding proteins, including pNiXa in Xenopus ovaries, unfertilized eggs, and embryos. A major goal of this research project is elucidating the role of pNiXa in the uptake, embryotoxicity, and teratogenicity of Ni{sup 2+} in Xenopus. To purify and identify pNiXa, ovarian tissue from mature Xenopus females was homogenized in 3 vol of Tris buffer and centrifuged. The supernatant was centrifuged; the ultracentrifugal supernatant was batch-adsorbed onto DEAE-cellulose. The pNiSa remained unbound and was subsequently adsorbed on phosphocellulose and eluted by a step-wise NaCl gradient. The pNiXa was eluted in 0.25 M NaCl; this fraction was concentrated, and further purified by reverse phase chromatography on a 5 {mu}m C-8 column, with a linear trifluoroacetic acid/acetonitrile gradient. The pNiXa was eluted at {approximately}56% acetonitrile, yielding a single protein band with mol wt {approximately}47 kD,based on SDS-PAGE analysis. Comparison of the amino acid composition of pNiXa versus the results obtained by automated Edman degradation indicated that the N-terminus of pNiXa was blocked. Sequencing of peptide fragments of pNiXa is underway.

  2. RIVAROXABAN: AN ORAL DIRECT INHIBITOR OF FACTOR X-A

    Directory of Open Access Journals (Sweden)

    Mehta Hiren R

    2011-08-01

    Full Text Available Venous thrombo embolism (VTE, which includes deep vein thrombosis and pulmonary embolism, is a major cause of morbidity and mortality in patients undergoing major orthopaedic surgery, and routine thrombo prophylaxis has been the standard of care over the last 20 years. Currently available options for the prevention of venous thrombo embolism in major orthopedic surgery include low-molecular-weight heparins, vitamin K antagonists and, more recently, the synthetic pentasaccharide fondaparinux. Although effective, these drugs have several limitations, and new oral antithrombotics offering predictable, effective and safe anticoagulation are strongly needed. This overview focuses on the most advanced oral direct inhibitors of factor Xa, rivaroxaban.Rivaroxaban, an oral oxazolidinone-based anticoagulant, is a potent, selective direct inhibitor of factor Xa that is used in the prevention of venous thrombo embolism in adult patients after total hip replacement (THR or total knee replacement (TKR surgery. In four large, clinical trials, oral rivaroxaban was more effective than subcutaneous enoxaparin in preventing postoperative VTE in patients undergoing total hip replacement or total knee replacement surgery. Notably, the superior efficacy of rivaroxaban was achieved with a low but not significant increase in the incidence of major bleeding episodes. In addition, preliminary pharma co-economic analyses in several countries indicate that rivaroxaban is a cost-effective treatment strategy versus enoxaparin. Although the position of rivaroxaban relative to other therapies remains to be fully determined, it is an effective emerging option for the prevention of venous thrombo embolism following total hip replacement and total knee replacement.

  3. Anti Xa monitoring during treatment with low molecular weight heparin or danaparoid: inter-assay variability.

    Science.gov (United States)

    Kitchen, S; Iampietro, R; Woolley, A M; Preston, F E

    1999-10-01

    If laboratory monitoring of low molecular weight heparin (LMWH) therapy is required the test of choice is the anti Xa activity assay. The relationship between anti Xa results obtained using different techniques is unknown. The aim of the present study was to compare anti Xa results obtained with eight different commercially available anti Xa activity assays (five chromogenic and three clotting based assays) in samples from patients receiving either therapeutic or prophylactic LMWH (enoxaparin or dalteparin) or danaparoid. We have demonstrated that highly significant differences exist between results obtained using different techniques. The mean anti Xa activity in patients receiving treatment or prophylaxis with enoxaparin ranged from 0.28 to 0.64 iu/ml. A similar relationship was present in samples from patients treated with dalteparin, mean anti Xa results ranging from 0.43 to 0.69 iu/ml. The Heptest clotting assay as used here in combination with the Automated Coagulation Laboratory instrument, was associated with lower results than other clotting or chromogenic techniques. In patients receiving danaparoid for heparin induced thrombocytopaenia (HIT) mean results with three clotting based assays were 0.30 to 0.36 u/ml, compared to mean results of 0.47 to 0.65 u/ml for chromogenic assays. Our data clearly indicate that the selection of anti Xa assay method could influence patient management since the dose required to achieve the therapeutic range would differ according to the assay employed. This is particularly important since the frequency of haemorrhagic side effects has been shown by others to be dose dependent, irrespective of the concomitant anti Xa activity results. In danaparoid therapy the clotting assays studied here should not be employed for monitoring without a modified target range, unless it can be demonstrated that the higher doses required to achieve the therapeutic range are safe. PMID:10544915

  4. Clinical Use of Anti-Xa Monitoring in Malignancy-Associated Thrombosis

    Directory of Open Access Journals (Sweden)

    Sarah Yentz

    2015-01-01

    Full Text Available Introduction. Low molecular weight heparin (LMWH is preferred for malignancy-associated venous thromboembolism (VTE. Many providers monitor LMWH with anti-Xa levels, despite little validation on correspondence with patient outcome. Methods. This is a retrospective, single institution study of anti-Xa measurement in malignancy-associated thrombosis. Cases were identified using the Electronic Data Warehouse, and inclusion was confirmed by two independent reviewers. Malignancy type, thrombotic history, measurement rationale and accuracy, clinical context, and management changes were evaluated. Results. 167 cases met inclusion criteria. There was no clear rationale for anti-Xa testing in 56%. Impaired renal function (10%, documented or suspected recurrent thrombosis despite anticoagulation (9%, and bleeding (6% were the most common reasons for testing. Incorrect measurement occurred in 44%. Renal impairment was not a significant impetus for testing, as 70% had a GFR > 60. BMI > 30 was present in 40%, and 28% had a BMI < 25. Clinical impact was low, as only 11% of patients had management changes. Conclusions. Provider education in accuracy and rationale for anti-Xa testing is needed. Our study illustrates uncertainty of interpretation and clinical impact of routine anti-Xa testing, as management was affected in few patients. It is not yet clear in which clinical context providers should send anti-Xa levels.

  5. Fast rotation of a subkilometer-sized near-Earth object 2011 XA{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Urakawa, Seitaro [Bisei Spaceguard Center, Japan Spaceguard Association, 1716-3 Okura, Bisei, Ibara, Okayama 714-1411 (Japan); Ohtsuka, Katsuhito [Tokyo Meteor Network, 1-27-5 Daisawa, Setagaya-ku, Tokyo 155-0032 (Japan); Abe, Shinsuke [Department of Aerospace Engineering, College of Science and Technology, Nihon University, 7-24-1 Narashinodai, Funabashi, Chiba 274-8501 (Japan); Ito, Takashi [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Nakamura, Tomoki, E-mail: urakawa@spaceguard.or.jp [Department of Earth and Planetary Material Sciences, Graduate School of Science, Tohoku University, Aoba, Sendai, Miyagi 980-8578 (Japan)

    2014-05-01

    We present light curve observations and their multiband photometry for near-Earth object (NEO) 2011 XA{sub 3}. The light curve has shown a periodicity of 0.0304 ± 0.0003 days (= 43.8 ± 0.4 minutes). The fast rotation shows that 2011 XA{sub 3} is in a state of tension (i.e., a monolithic asteroid) and cannot be held together by self-gravitation. Moreover, the multiband photometric analysis indicates that the taxonomic class of 2011 XA{sub 3} is S-complex, or V-type. Its estimated effective diameter is 225 ± 97 m (S-complex) and 166 ± 63 m (V-type), respectively. Therefore, 2011 XA{sub 3} is a candidate for the second-largest, fast-rotating, monolithic asteroid. Moreover, the orbital parameters of 2011 XA{sub 3} are apparently similar to those of NEO (3200) Phaethon, but F/B-type. We computed the orbital evolutions of 2011 XA{sub 3} and Phaethon. However, the results of the computation and distinct taxonomy indicate that neither of the asteroids is of common origin.

  6. Rice XB15, a protein phosphatase 2C, negatively regulates cell death and XA21-mediated innate immunity.

    Directory of Open Access Journals (Sweden)

    Chang-Jin Park

    2008-09-01

    Full Text Available Perception of extracellular signals by cell surface receptors is of central importance to eukaryotic development and immunity. Kinases that are associated with the receptors or are part of the receptors themselves modulate signaling through phosphorylation events. The rice (Oryza sativa L. XA21 receptor kinase is a key recognition and signaling determinant in the innate immune response. A yeast two-hybrid screen using the intracellular portion of XA21, including the juxtamembrane (JM and kinase domain as bait, identified a protein phosphatase 2C (PP2C, called XA21 binding protein 15 (XB15. The interaction of XA21 and XB15 was confirmed in vitro and in vivo by glutathione-S-transferase (GST pull-down and co-immunoprecipitation assays, respectively. XB15 fusion proteins purified from Escherichia coli and from transgenic rice carry PP2C activity. Autophosphorylated XA21 can be dephosphorylated by XB15 in a temporal- and dosage-dependent manner. A serine residue in the XA21 JM domain is required for XB15 binding. Xb15 mutants display a severe cell death phenotype, induction of pathogenesis-related genes, and enhanced XA21-mediated resistance. Overexpression of Xb15 in an XA21 rice line compromises resistance to the bacterial pathogen Xanthomonas oryzae pv. oryzae. These results demonstrate that Xb15 encodes a PP2C that negatively regulates the XA21-mediated innate immune response.

  7. 3D/3D registration of coronary CTA and biplane XA reconstructions for improved image guidance

    Energy Technology Data Exchange (ETDEWEB)

    Dibildox, Gerardo, E-mail: g.dibildox@erasmusmc.nl; Baka, Nora; Walsum, Theo van [Biomedical Imaging Group Rotterdam, Departments of Radiology and Medical Informatics, Erasmus Medical Center, 3015 GE Rotterdam (Netherlands); Punt, Mark; Aben, Jean-Paul [Pie Medical Imaging, 6227 AJ Maastricht (Netherlands); Schultz, Carl [Department of Cardiology, Erasmus Medical Center, 3015 GE Rotterdam (Netherlands); Niessen, Wiro [Quantitative Imaging Group, Faculty of Applied Sciences, Delft University of Technology, 2628 CJ Delft, The Netherlands and Biomedical Imaging Group Rotterdam, Departments of Radiology and Medical Informatics, Erasmus Medical Center, 3015 GE Rotterdam (Netherlands)

    2014-09-15

    Purpose: The authors aim to improve image guidance during percutaneous coronary interventions of chronic total occlusions (CTO) by providing information obtained from computed tomography angiography (CTA) to the cardiac interventionist. To this end, the authors investigate a method to register a 3D CTA model to biplane reconstructions. Methods: The authors developed a method for registering preoperative coronary CTA with intraoperative biplane x-ray angiography (XA) images via 3D models of the coronary arteries. The models are extracted from the CTA and biplane XA images, and are temporally aligned based on CTA reconstruction phase and XA ECG signals. Rigid spatial alignment is achieved with a robust probabilistic point set registration approach using Gaussian mixture models (GMMs). This approach is extended by including orientation in the Gaussian mixtures and by weighting bifurcation points. The method is evaluated on retrospectively acquired coronary CTA datasets of 23 CTO patients for which biplane XA images are available. Results: The Gaussian mixture model approach achieved a median registration accuracy of 1.7 mm. The extended GMM approach including orientation was not significantly different (P > 0.1) but did improve robustness with regards to the initialization of the 3D models. Conclusions: The authors demonstrated that the GMM approach can effectively be applied to register CTA to biplane XA images for the purpose of improving image guidance in percutaneous coronary interventions.

  8. Role of Factor Xa Inhibitors in Cancer-Associated Thrombosis: Any New Data?

    Directory of Open Access Journals (Sweden)

    Ali Zalpour

    2011-01-01

    Full Text Available The association between cancer and venous thromboembolism (VTE has been well documented in the literature. Prevention and treatment of VTE in cancer patients is imperative. Typically, the mainstay regimen for VTE prevention and treatment has been anticoagulation therapy, unless contraindicated. This therapy consists of unfractionated heparin (UFH, low-molecular-weight heparin (LMWH, factor Xa inhibitor, or vitamin K antagonist (VKA. Current guidelines recommend LMWH over VKA for the treatment of VTE in cancer patients. Factor-specific anticoagulants have been proven safe and effective, and recently factor Xa inhibitors have emerged as a treatment alternative to heparins and VKA. Currently, three factor Xa inhibitors have been identified: fondaparinux (the only one approved so far by the US Food and Drug Administration, idraparinux (in clinical trials, and idrabiotaparinux (in clinical trials. This paper will examine the role of these agents, focusing on fondaparinux, for the prevention and treatment of VTE in cancer patients.

  9. The Matrix Equation XA- AX=Xαg(X over Fields or Rings

    Directory of Open Access Journals (Sweden)

    Gerald Bourgeois

    2014-01-01

    Full Text Available Let n,α∈N≥2 and let K be an algebraically closed field with characteristic 0 or greater than n. We show that if f∈K[X] and A,B∈Mn(K satisfy [A,B]=f(A, then A,B are simultaneously triangularizable. Let R be a reduced ring such that n! is not a zero divisor and let A be a generic matrix over R; we show that X=0 is the sole solution of AX-XA=Xα. Let R be a commutative ring with unity; let A be similar to diag(λ1In1,…,λrInr such that, for every i≠j,λi-λj is not a zero divisor. If X is a nilpotent solution of XA-AX=Xαg(X where g∈R[X], then AX=XA.

  10. On Diophantine Equations of the Form $(x-a_1)(x-a_2)\\ldots(x-a_k)+r=y^n$

    Indian Academy of Sciences (India)

    Manisha Kulkarni; B Sury

    2011-08-01

    Erdős and Selfridge [3] proved that a product of consecutive integers can never be a perfect power. That is, the equation $x(x+1)(x+2)\\ldots(x+(m-1))=y^n$ has no solutions in positive integers $x,m,n$ where $m,n>1$ and $y\\in Q$. We consider the equation $$(x-a_1)(x-a_2)\\ldots(x-a_k)+r=y^n$$ where $0≤ a_1 < a_2 <\\cdots < a_k$ are integers and, with $r\\in Q,n≥ 3$ and we prove a finiteness theorem for the number of solutions in $Z,y$ in . Following that, we show that, more interestingly, for every nonzero integer >2 and for any nonzero integer which is not a perfect -th power for which the equation admits solutions, is bounded by an effective bound.

  11. Molecular analysis of two cDNAs encoding Xa1 and oxysterol binding proteins in sorghum (Sorghum bicolor)

    Science.gov (United States)

    Using suppression subtractive hybridization (SSH) and subsequent microarray analysis, expression profiles of sorghum genes responsive to greenbug phloem-feeding were obtained and identified. Among the profiles, two cDNAs designated to MM73 and MM95 were identified to encode Xa1 (Xa1) and oxysterol ...

  12. Introduction of a rice blight resistance gene, Xa21, into five Chinese rice varieties through an Agrobacterium-mediated system

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A cloned gene, Xa21 was transferred into five widely-used Chinese rice varieties through an Agrobacterium-mediated system, and over 110 independent transgenic lines were obtained. PCR and Southern analysis of transgenic plants revealed the integration of the whole Xa21 gene into the host genomes. The integrated Xa21 gene was stably inherited, and segregated in a 3∶1 ratio in the selfed T1 generation when one copy of the gene was integrated in the transformants. Inoculation tests displayed that transgenic T0 plants and Xa21 PCR-positive T1 plants were highly resistant to bacterial blight disease. The selected Xa21 homozygous resistant transgenic lines with desirable qualities may be propagated as new varieties or utilized in hybrid rice breeding.

  13. Introduction of a rice blight resistance gene, Xa21, into five Chinese rice varieties through an Agrobacterium -mediated system

    Institute of Scientific and Technical Information of China (English)

    翟文学; 李晓兵; 田文忠; 周永力; 潘学彪; 曹守云; 赵显峰; 赵彬; 章琦; 朱立煌

    2000-01-01

    A cloned gene, Xa21 was transferred into five widely-used Chinese rice varieties through an Agrobacterium-mediated system, and over 110 independent transgenic lines were obtained. PCR and Southern analysis of transgenic plants revealed the integration of the whole Xa21 gene into the host genomes. The integrated Xa21 gene was stably inherited, and segregated in a 3 : 1 ratio in the selfed T1 generation when one copy of the gene was integrated in the transfor-mants. Inoculation tests displayed that transgenic T0 plants and Xa21 PCR-positive T1 plants were highly resistant to bacterial blight disease. The selected Xa21 homozygous resistant transgenic lines with desirable qualities may be propagated as new varieties or utilized in hybrid rice breeding.

  14. Pleiotropic effects of factor Xa and thrombin : what to expect from novel anticoagulants

    NARCIS (Netherlands)

    Spronk, Henri M. H.; de Jong, Anne Margreet; Crijns, Harry J.; Schotten, Ulrich; Van Gelder, Isabelle C.; ten Cate, Hugo

    2014-01-01

    Factor Xa and thrombin are well-known components of the coagulation cascade and have been proven to be viable targets for effective anticoagulation treatment. However, accumulating evidence suggests that these serine proteases are also crucial modulators of other cellular mechanisms through the acti

  15. Factor Xa : at the crossroads between coagulation and signaling in physiology and disease

    NARCIS (Netherlands)

    Borensztajn, Keren; Peppelenbosch, Maikel P.; Spek, C. Arnold

    2008-01-01

    Activated factor Xa (FXa) is traditionally known as an important player in the coagulation cascade responsible for thrombin generation. Long considered a passive bystander, it is now evident that FXa exerts direct effects on a wide variety of cell types via activation of its two main receptors, prot

  16. The role of structural information in the discovery of direct thrombin and factor Xa inhibitors.

    Science.gov (United States)

    Nar, Herbert

    2012-05-01

    The quest for novel medications to treat thromboembolic disorders such as venous thrombosis, pulmonary embolism and stroke received a boost when the 3D structures of two major players in the blood coagulation cascade were determined in 1989 and 1993. Structure-guided design of inhibitors of thrombin (factor IIa, fIIa) and factor Xa (fXa) eventually led to the discovery of potent, selective, efficacious, orally active and safe compounds that proved successful in clinical studies. In 2008, the direct thrombin inhibitor dabigatran etexilate developed by Boehringer Ingelheim became the first novel antithrombotic molecular entity to enter the market in 50 years. Additional compounds targeting factor Xa were subsequently granted marketing authorization or are in late-stage clinical studies. In this review, I use selected case studies to describe the discovery of novel fIIa and fXa inhibitors, with a particular emphasis on the pre-eminent role that structural information played in this process. PMID:22503439

  17. Data of evolutionary structure change: 1B5XA-2G4NF [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1B5XA-2G4NF 1B5X 2G4N A F KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYN...G HHHH -GGGG -- EVID>EVID> 0 2G4N F 2G4NF ELKDL...242798 2.054610013961792 4.014041900634766 ...EVID> 1 2G4N F 2G4NF

  18. Factor Xa generation by computational modeling: an additional discriminator to thrombin generation evaluation.

    Directory of Open Access Journals (Sweden)

    Kathleen E Brummel-Ziedins

    Full Text Available Factor (fXa is a critical enzyme in blood coagulation that is responsible for the initiation and propagation of thrombin generation. Previously we have shown that analysis of computationally generated thrombin profiles is a tool to investigate hemostasis in various populations. In this study, we evaluate the potential of computationally derived time courses of fXa generation as another approach for investigating thrombotic risk. Utilizing the case (n = 473 and control (n = 426 population from the Leiden Thrombophilia Study and each individual's plasma protein factor composition for fII, fV, fVII, fVIII, fIX, fX, antithrombin and tissue factor pathway inhibitor, tissue factor-initiated total active fXa generation was assessed using a mathematical model. FXa generation was evaluated by the area under the curve (AUC, the maximum rate (MaxR and level (MaxL and the time to reach these, TMaxR and TMaxL, respectively. FXa generation was analyzed in the entire populations and in defined subgroups (by sex, age, body mass index, oral contraceptive use. The maximum rates and levels of fXa generation occur over a 10- to 12- fold range in both cases and controls. This variation is larger than that observed with thrombin (3-6 fold in the same population. The greatest risk association was obtained using either MaxR or MaxL of fXa generation; with an ∼2.2 fold increased risk for individuals exceeding the 90(th percentile. This risk was similar to that of thrombin generation(MaxR OR 2.6. Grouping defined by oral contraceptive (OC use in the control population showed the biggest differences in fXa generation; a >60% increase in the MaxR upon OC use. FXa generation can distinguish between a subset of individuals characterized by overlapping thrombin generation profiles. Analysis of fXa generation is a phenotypic characteristic which may prove to be a more sensitive discriminator than thrombin generation among all individuals.

  19. A Single-Tube, Functional Marker-Based Multiplex PCR Assay for Simultaneous Detection of Major Bacterial Blight Resistance GenesXa21, xa13 andxa5 in Rice

    Institute of Scientific and Technical Information of China (English)

    S. K. HAJIRA; M. ANILA; S. BHASKAR; V. ABHILASH; H. K. MAHADEVASWAMY; M. KOUSIK; T. DILIPKUMAR; G. HARIKA; G. REKHA; R. M. SUNDARAM; G. S. LAHA; A. YUGANDER; S. M. BALACHANDRAN; B. C. VIRAKTAMATH; K. SUJATHA; C. H. BALACHIRANJEEVI; K. PRANATHI

    2016-01-01

    In marker-assisted breeding for bacterial blight (BB) resistance in rice, three major resistance genes, viz.,Xa21, xa13andxa5,are routinely deployed either singly or in combinations. As efficient and functional markers are yet to be developed forxa13 andxa5,we have developed simple PCR-based functional markers for both the genes.Forxa13,we designed a functional PCR-based marker, xa13-prom targeting the InDel polymorphism in the promoter of candidate geneOs8N3 located on chromosome 8 of rice. With respect toxa5, a multiplex-PCR based functional marker system, named xa5FM, consisting of two sets of primer pairs targeting the 2-bp functional nucleotide polymorphism in the exon II of the geneTFIIAɤ5 (candidate forxa5), has been developed. Both xa13-prom and xa5FM can differentiate the resistant and susceptible alleles forxa13 andxa5, respectively, in a co-dominant fashion. Using these two functional markers along with the already reported functional PCR-based marker forXa21 (pTA248),we designed a single-tube multiplex PCR based assay for simultaneous detection of all the three major resistance genes and demonstrated the utility of the multiplex marker system in a segregating population.

  20. Comparative nutritional compositions and proteomics analysis of transgenic Xa21 rice seeds compared to conventional rice.

    Science.gov (United States)

    Gayen, Dipak; Paul, Soumitra; Sarkar, Sailendra Nath; Datta, Swapan K; Datta, Karabi

    2016-07-15

    Transgenic rice expressing the Xa21 gene have enhanced resistant to most devastating bacterial blight diseases caused by Xanthomonas oryzae pv. oryzae (Xoo). However, identification of unintended modifications, owing to the genetic modification, is an important aspect of transgenic crop safety assessment. In this study, the nutritional compositions of seeds from transgenic rice plants expressing the Xa21 gene were compared against non-transgenic rice seeds. In addition, to detect any changes in protein translation levels as a result of Xa21 gene expression, rice seed proteome analyses were also performed by two-dimensional gel electrophoresis. No significant differences were found in the nutritional compositions (proximate components, amino acids, minerals, vitamins and anti-nutrients) of the transgenic and non-transgenic rice seeds. Although gel electrophoresis identified 11 proteins that were differentially expressed between the transgenic and non-transgenic seed, only one of these (with a 20-fold up-regulation in the transgenic seed) shows nutrient reservoir activity. No new toxins or allergens were detected in the transgenic seeds. PMID:26948618

  1. A novel prothrombin time assay for assessing the anticoagulant activity of oral factor Xa inhibitors.

    Science.gov (United States)

    Barrett, Yu Chen; Wang, Zhaoqing; Knabb, Robert M

    2013-09-01

    Conventional prothrombin time (PT) assays have limited sensitivity and dynamic range in monitoring the anticoagulant activity of direct factor Xa inhibitors. Hence, new assays are needed. We modified a PT assay by adding calcium chloride (CaCl2) to the thromboplastin reagent to increase assay dynamic range and improve sensitivity. Effects of calcium and sodium ion concentrations, and sample handling, were evaluated to optimize assay performance. Increasing concentrations of calcium ions produced progressive increases in PT across the factor Xa inhibitor concentrations of 0 to 2500 nmol/L for razaxaban and apixaban. The greatest effect was seen when the thromboplastin reagent was diluted 1:2.25 with 100 mmol/L CaCl2 (thus selected for routine use). The optimized assay showed an interassay precision of 1.5 to 9.3 percentage coefficient of variation (%CV) for razaxaban and 3.1 to 4.6 %CV for apixaban. We conclude that the modified PT assay is likely to be suitable as a pharmacodynamic marker for activity at therapeutic concentrations of factor Xa inhibitors.

  2. The phylogenetically-related pattern recognition receptors EFR and XA21 recruit similar immune signaling components in monocots and dicots.

    Directory of Open Access Journals (Sweden)

    Nicholas Holton

    2015-01-01

    Full Text Available During plant immunity, surface-localized pattern recognition receptors (PRRs recognize pathogen-associated molecular patterns (PAMPs. The transfer of PRRs between plant species is a promising strategy for engineering broad-spectrum disease resistance. Thus, there is a great interest in understanding the mechanisms of PRR-mediated resistance across different plant species. Two well-characterized plant PRRs are the leucine-rich repeat receptor kinases (LRR-RKs EFR and XA21 from Arabidopsis thaliana (Arabidopsis and rice, respectively. Interestingly, despite being evolutionary distant, EFR and XA21 are phylogenetically closely related and are both members of the sub-family XII of LRR-RKs that contains numerous potential PRRs. Here, we compared the ability of these related PRRs to engage immune signaling across the monocots-dicots taxonomic divide. Using chimera between Arabidopsis EFR and rice XA21, we show that the kinase domain of the rice XA21 is functional in triggering elf18-induced signaling and quantitative immunity to the bacteria Pseudomonas syringae pv. tomato (Pto DC3000 and Agrobacterium tumefaciens in Arabidopsis. Furthermore, the EFR:XA21 chimera associates dynamically in a ligand-dependent manner with known components of the EFR complex. Conversely, EFR associates with Arabidopsis orthologues of rice XA21-interacting proteins, which appear to be involved in EFR-mediated signaling and immunity in Arabidopsis. Our work indicates the overall functional conservation of immune components acting downstream of distinct LRR-RK-type PRRs between monocots and dicots.

  3. Recent advances in the development of factor Xa%Xa因子抑制剂的研究进展

    Institute of Scientific and Technical Information of China (English)

    江凯; 张惠斌; 周金培; 邢俊豪

    2012-01-01

    Xa因子是一个维生素K依赖的丝氨酸蛋白酶,它占据了凝血瀑布反应中的中心位置,可以由内源性和外源性凝血途径激活,其位置特殊性决定了其作用的重要性.利伐沙班等Xa因子抑制剂作为未来重要的口服抗血栓药物已上市,相关的其他方面的药理作用也成为研究热点.文中对Xa因子的结构、作用模式及不同结构抑制剂的最新研究进展做一综述.%Factor Xa (fXa) is a Vk dependent serine protease playing a crucial role in the blood coagulation cascade. It occupies the central position in the coagulation cascade as the convergence point between intrinsic and extrinsic pathways, which decides its significance in role. Rivaroxaban and several other fXa inhibitors have been approved for antithrombus treatment. Related pharmacological studies also become hotspots. In this review, we will illustrate the structure of factor Xa, the action mode between the inhibitors and fXa, and the recent research advances of fXa inhibitors with different structures.

  4. Fine mapping of the rice bacterial blight resistance gene Xa-4 and its co-segregation marker

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    An F2 population developed from the Xa-4 near isogenic lines,IR24 and IRBB4,was used for fine mapping of the rice bacterial blight resistance gene,Xa-4.Some restriction fragment length polymorphism (RFLP) markers on the high-density map constructed by Harushima et al.and the amplified DNA fragments homologous to the conserved domains of plant disease resistance (R) genes were used to construct the genetic linkage map around the gene Xa-4 by scoring susceptible individuals in the population.Xa-4 was mapped between the RFLP marker G181 and the polymerase chain reaction (PCR) marker M55.The R gene homologous fragment marker RS13 was found co-segregating with Xa-4 by analyzing all the plants in the population.This result opened an approach to map-based cloning of this gene,and marker RS13 can be applied to molecular marker-assisted selection of Xa-4 in rice breeding programs.

  5. Assessment of apixaban plasma levels by laboratory tests: suitability of three anti-Xa assays. A multicentre French GEHT study.

    Science.gov (United States)

    Gouin-Thibault, Isabelle; Flaujac, Claire; Delavenne, Xavier; Quenet, Sara; Horellou, Marie-Hélenè; Laporte, Silvy; Siguret, V; Lecompte, T

    2014-02-01

    While laboratory monitoring is not required in patients treated with apixaban, a direct factor-Xa inhibitor, assessment of its concentration is useful in some critical situations. However, few data are available on its effect on coagulation tests and on the suitability of anti-Xa assays for its quantification. It was the objective of this study to identify laboratory tests suitable for apixaban concentration assessment. Coagulation tests - PT and aPTT- and anti-Xa assays were performed in apixaban-spiked plasma samples. To evaluate the sensitivity of PT and aPTT to apixaban, we conducted a first monocenter part, with a wide range of concentrations (50-1,000 ng/ml), a large panel of reagents (20 reagents), and two coagulometers (STAR®, Stago and ACL TOP®, IL), and a second multicenter part involving 13 laboratories using either a common PT reagent (RecombiPlastin2G®) or the local PT and aPTT reagents. In the multicentre part, five blinded apixaban-spiked plasma samples (0/100/200/400/800 ng/ml - checked by HPLC-MS/MS) were used; apixaban concentrations were measured with three anti-Xa assays, apixaban calibrators and controls (Stago). PT and aPTT tests using a large panel of reagents displayed a low sensitivity to a wide range of apixaban concentrations. The concentrations to double PT ranged from 400 to >1,000 ng/ml with the 10 reagents. With the three anti-Xa assays, inter-laboratory precision and accuracy were below 11% and 12%, respectively. In conclusion, whereas PT and aPTT tests were not sensitive enough to detect apixaban, the three anti-Xa assays tested using lyophilised apixaban calibrators and controls allowed to reliably quantify a wide range of apixaban concentrations.

  6. Identification and gene prediction of a 24 kb region containing xa5, a recessive bacterial blight resistance gene in rice (Oryza sativa L.)

    Institute of Scientific and Technical Information of China (English)

    ZHONG Yiming; JIANG Guanghuai; CHEN Xuewei; XIA Zhihui; LI Xiaobing; ZHU Lihuang; ZHAI Wenxue

    2003-01-01

    Rice xa5 gene provides recessive, race-specific resistance to bacterial blight disease caused by the pathogen Xanthomonas oryzae pv. oryzae and has great value for research and breeding. In an effort to clone xa5, an F2 population of 4892 individuals was developed from the xa5 near isogenic lines, IR24 and IRBB5. A fine mapping procedure was conducted and tightly linked RFLP markers were used to screen a BAC library of IRBB56, a resistant rice line containing the xa5 gene. A 213 kb contig covering the xa5 locus was constructed. According to the sequences from the International Rice Genome Sequening Project (IRGSP), the Chinese Superhybrid Rice Genome Project (SRGP) and some sub-clones of the contig, twelve SSLP and CAPS markers were developed for fine mapping. The xa5 gene was mapped to a 0.3 cM interval between markers K5 and T4, which spanned an interval of approximately 24 kb, co-segregating with marker T2. Sequence analysis of the 24 kb region revealed that an ABC transporter and a basal transcription factor (TFIIa) were potential candidates for the xa5 resistance gene product. The molecular mechanism by which the xa5 gene provides recessive, race-specific resistance to bacterial blight will be elucidated by the functional tests of the 24 kb DNA and the candidate genes.

  7. Hysteresis-like binding of coagulation factors X/Xa to procoagulant activated platelets and phospholipids results from multistep association and membrane-dependent multimerization.

    Science.gov (United States)

    Podoplelova, Nadezhda A; Sveshnikova, Anastasia N; Kurasawa, James H; Sarafanov, Andrey G; Chambost, Herve; Vasil'ev, Sergey A; Demina, Irina A; Ataullakhanov, Fazly I; Alessi, Marie-Christine; Panteleev, Mikhail A

    2016-06-01

    Binding of coagulation factors X (fX) and Xa (fXa) to activated platelets is required for the formation of membrane-dependent enzymatic complexes of intrinsic tenase and prothrombinase. We carried out an in-depth characterization of fX/fXa binding to phospholipids and gel-filtered, thrombin-activated platelets. Flow cytometry, surface plasmon resonance, and computational modeling were used to investigate interactions of fX/fXa with the membranes. Confocal microscopy was employed to study fXa binding to platelet thrombi formed in flowing whole blood under arterial conditions. Binding of fX/fXa to either vesicles or procoagulant platelets did not follow a traditional one-step reversible binding model. Their dissociation was a two-step process resulting in a plateau that was up to 10-fold greater than the saturation value observed in the association experiments. Computational modeling and experimental evidence suggested that this was caused by a combination of two-step association (mainly for fX) and multimerization on the membrane (mainly for fXa). Importantly, fX formed multimers with fXa, thereby improving its retention. The same binding/dissociation hysteresis was observed for annexin V known to form trimers on the membranes. Experiments with platelets from gray syndrome patients showed that alpha-granular factor Va provided an additional high-affinity binding site for fXa that did not affect the hysteresis. Confocal microscopy observation of fXa binding to platelet thrombi in a flow chamber and its wash-out confirmed that this phenomenon persisted under physiologically relevant conditions. This suggests its possible role of "locking" coagulation factors on the membrane and preventing their inhibition in plasma and removal from thrombi by flow.

  8. Basis for the Specificity and Activation of the Serpin Protein Z-dependent Proteinase Inhibitor (ZPI) as an Inhibitor of Membrane-associated Factor Xa

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xin; Dementiev, Alexey; Olson, Steven T.; Gettins, Peter G.W. (UIC)

    2012-12-13

    The serpin ZPI is a protein Z (PZ)-dependent specific inhibitor of membrane-associated factor Xa (fXa) despite having an unfavorable P1 Tyr. PZ accelerates the inhibition reaction {approx}2000-fold in the presence of phospholipid and Ca{sup 2+}. To elucidate the role of PZ, we determined the x-ray structure of Gla-domainless PZ (PZ{sub {Delta}GD}) complexed with protein Z-dependent proteinase inhibitor (ZPI). The PZ pseudocatalytic domain bound ZPI at a novel site through ionic and polar interactions. Mutation of four ZPI contact residues eliminated PZ binding and membrane-dependent PZ acceleration of fXa inhibition. Modeling of the ternary Michaelis complex implicated ZPI residues Glu-313 and Glu-383 in fXa binding. Mutagenesis established that only Glu-313 is important, contributing {approx}5-10-fold to rate acceleration of fXa and fXIa inhibition. Limited conformational change in ZPI resulted from PZ binding, which contributed only {approx}2-fold to rate enhancement. Instead, template bridging from membrane association, together with previously demonstrated interaction of the fXa and ZPI Gla domains, resulted in an additional {approx}1000-fold rate enhancement. To understand why ZPI has P1 tyrosine, we examined a P1 Arg variant. This reacted at a diffusion-limited rate with fXa, even without PZ, and predominantly as substrate, reflecting both rapid acylation and deacylation. P1 tyrosine thus ensures that reaction with fXa or most other arginine-specific proteinases is insignificant unless PZ binds and localizes ZPI and fXa on the membrane, where the combined effects of Gla-Gla interaction, template bridging, and interaction of fXa with Glu-313 overcome the unfavorability of P1 Tyr and ensure a high rate of reaction as an inhibitor.

  9. Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation

    NARCIS (Netherlands)

    Borensztajn, Keren S.; Bijlsma, Maarten F.; Groot, Angelique P.; Bruggemann, Lois W.; Versteeg, Henri H.; Reitsma, Pieter H.; Peppelenbosch, Maikel P.; Spek, C. Arnold

    2007-01-01

    Coagulation Factor (F)Xa is a serine protease that plays a crucial role during blood coagulation by converting prothrombin into active thrombin. Recently, however, it emerged that besides this role in coagulation, FXa induces intracellular signaling leading to different cellular effects. Here, we sh

  10. Advances in coagulation factor Xa inhibitor%凝血因子Xa抑制药研究进展

    Institute of Scientific and Technical Information of China (English)

    黄震华

    2012-01-01

    Factor Xa is located at the intersection of the intrinsic and extrinsic pathways in the coagulation cascade. The newer anticoagulant drugs targeting factor Xa have the advantage of good efficacy, more convenience, no laboratory monitoring, and less bleeding side effect. Indirect factor Xa inhibitor fondaparinux, idraparinux, idrabiotaparinux, SR123781 and direct factor Xa inhibitor rivaroxaban, apixaban, betrixaban, edoxaban, eribaxaban, LY517717, YM150, letaxaban, otamixaban are the more studied drugs nowadays.%凝血因子Xa是内源性凝血系统和外源性凝血系统的交汇点.针对凝血因子Xa的新型抗凝药物具有疗效显著、使用方便、不需实验室监测、出血不良反应少等优点.间接凝血因子Xa抑制药璜达肝素、艾屈肝素、idrabiotaparinux、SR123781和直接凝血因子Xa抑制药利伐沙班、apixaban、betrixaban、edoxaban、eribaxaban、LY517717、YM150、letaxaban、奥米沙班是目前研究较多的药物.

  11. Magnetization of mixed ferri-ferrimagnets composed of Prussian blue analogs A1xA21-xB

    Institute of Scientific and Technical Information of China (English)

    Jiang Wei; Guan Hong-Yu; Lo Weng-Cheng

    2011-01-01

    The magnetization of ternary metal Prussian blue analogues A1xA21-xB, formed by three different sublattices A1, A2 and B, is studied by using the effective-field theory with self-spin correlations. Effects of the mole fraction x,the anisotropy and the transverse magnetic field on the magnetization are discussed.

  12. 800 XA Application in Prco es Automation of High Titanium Slag Furnace%800 XA 在高钛渣炉过程自动化中的应用

    Institute of Scientific and Technical Information of China (English)

    杨春旺

    2013-01-01

    Combined with special requirements of manufacturing technology for the high titanium slag DC electric arc furnace and distinct characteristics of ABB -800XA system, the operation practices of the optimization design and configuration for the production process automation with ABB -800 XA system were expounded so as to a-chieve the optimization control for technological process of high titanium slag DC electric arc furnace .%结合高钛渣直流电弧炉生产工艺的特殊需求与ABB-800 XA系统的鲜明特点,阐述了采用后者对生产过程自动化进行优化设计与配置的运用实践,从而实现了对高钛渣直流电弧炉工艺过程的优化控制。

  13. Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

    Directory of Open Access Journals (Sweden)

    Upreti VV

    2013-04-01

    Full Text Available Vijay V Upreti,1 Yan Song,1 Jessie Wang,2 Wonkyung Byon,3 Rebecca A Boyd,3 Janice M Pursley,4 Frank LaCreta,1 Charles E Frost1 1Clinical Pharmacology and Pharmacometrics, Discovery Medicine and Clinical Pharmacology, 2Exploratory Development Global Biometric Sciences, Bristol-Myers Squibb, Princeton, NJ, 3Primary Care Clinical Pharmacology, Pfizer, Groton, CT, 4Analytical and Bioanalytical Department, Bristol-Myers Squibb, Princeton, NJ, USA Background: Apixaban is an oral, selective, direct factor Xa inhibitor approved for thromboprophylaxis after orthopedic surgery and stroke prevention in patients with atrial fibrillation, and under development for treatment of venous thromboembolism. This study investigated the effect of a gastric acid suppressant, famotidine (a histamine H2-receptor antagonist, on the pharmacokinetics of apixaban in healthy subjects. Methods: This two-period, two-treatment crossover study randomized 18 healthy subjects to receive a single oral dose of apixaban 10 mg with and without a single oral dose of famotidine 40 mg administered 3 hours before dosing with apixaban. Plasma apixaban concentrations were measured up to 60 hours post-dose and pharmacokinetic parameters were calculated. Results: Famotidine did not affect maximum apixaban plasma concentration (Cmax or area under the plasma concentration-time curve from zero to infinite time (AUC∞. Point estimates for ratios of geometric means with and without famotidine were close to unity for Cmax (0.978 and AUC∞ (1.007, and 90% confidence intervals were entirely contained within the 80%–125% no-effect interval. Administration of apixaban alone and with famotidine was well tolerated. Conclusion: Famotidine does not affect the pharmacokinetics of apixaban, consistent with the physicochemical properties of apixaban (lack of an ionizable group and pH-independent solubility. Apixaban pharmacokinetics would not be affected by an increase in gastrointestinal pH due to

  14. Antithrombotic and anticoagulant effects of direct factor Xa inhibitor darexaban in rat and rabbit models of venous thrombosis.

    Science.gov (United States)

    Kaku, Seiji; Uemura, Toshio; Saitoh, Minori; Suzuki, Ken-ichi; Iwatsuki, Yoshiyuki; Funatsu, Toshiyuki; Kawasaki, Tomihisa

    2013-01-15

    The oral direct factor Xa inhibitor darexaban administered intraduodenally prevented venous thrombus formation in both rats and rabbits with no effect on bleeding. The indirect parenteral Factor Xa inhibitor fondaparinux exerted similar properties, only prolonging bleeding time at extremely high doses. In contrast, the thrombin inhibitor ximelagatran and low-molecular-weight heparin enoxaparin prolonged bleeding time at antithrombotic doses. Studies using human platelets showed darexaban glucuronide, a darexaban metabolite that predominantly determines darexaban antithrombotic effects in vivo, had no effect on platelet activation and aggregation, while heparin and enoxaparin activated platelets. Melagatran, heparin, and enoxaparin all inhibited thrombin-induced platelet aggregation at clinically relevant concentrations. Taken together, these results suggest that thrombin-inhibiting drugs may increase the risk of bleeding, while darexaban may have potential as an orally available antithrombotic agent with a wide therapeutic window. PMID:23200896

  15. 争奇斗艳——丰田改装车Scion xA speedster

    Institute of Scientific and Technical Information of China (English)

    志华

    2006-01-01

    世界上的车展纷繁众多,有个叫SEMA的车展每年固定在赌城拉斯维加斯举行,车展的主题就是一个字:“怪”!丰田的这款Scion xA speedster就是其中之一小怪车。

  16. Comparative study of Factor Xa fluorogenic substrates and their influence on the quantification of LMWHs.

    Science.gov (United States)

    Castro-López, Vanessa; Harris, Leanne F; O'Donnell, James S; Killard, Anthony J

    2011-01-01

    Low molecular weight heparins (LMWHs) are recognised as the preferred anticoagulants in the prevention and treatment of venous thromboembolism. Anti-Factor Xa (anti-FXa) levels are used to monitor the anticoagulant effect of LMWHs and such assays are routinely employed in hospital diagnostic laboratories. In this study, a fluorogenic anti-FXa assay was developed using a commercially available fluorogenic substrate with an attached 6-amino-1-naphthalene-sulfonamide (ANSN) fluorophore and was used for the determination of two LMWHs, enoxaparin and tinzaparin and the heparinoid, danaparoid. The assay was based on the complexation of heparinised plasma with 100 nM exogenous FXa and 25 μM of the fluorogenic substrate Mes-D-LGR-ANSN (C(2)H(5))(2) (SN-7). The assay was tested with pooled plasma samples spiked with anticoagulant concentrations in the range 0-1.6 U mL(-1). The statistically sensitive assay range was 0-0.4 U mL(-1) for enoxaparin and tinzaparin and 0-0.2 U mL(-1) for danaparoid, with assay variation typically below 10.5%. This assay was then compared with a previously published fluorogenic anti-FXa assay developed with the peptide substrate, methylsulfonyl-D: -cyclohexylalanyl-glycyl-arginine-7-amino-4-methylcoumarin acetate (Pefafluor FXa). Both assays were compared in terms of fluorescence intensity, lag times and sensitivity to anticoagulants. PMID:20972772

  17. Chandra Imaging and Spectroscopy of the Eastern XA Region of the Cygnus Loop Supernova Remnant

    CERN Document Server

    McEntaffer, Randall L

    2011-01-01

    The XA region of the Cygnus Loop is a bright knot of X-ray emission on the eastern edge of the supernova remnant resulting from the interaction of the supernova blast wave with density enhancements at the edge of a precursor formed cavity. To study the nature and origin of the X-ray emission we use high spatial resolution images from Chandra. Our goal is to probe the density of various spectral extraction regions to form a picture of the cavity wall and characterize the interaction between this supernova and the local interstellar medium. We find that a series of regions along the edge of the X-ray emission appears to trace out the location of the cavity wall. The best fit plasma models result in two temperature component equilibrium models for each region. The low temperature components have densities that are an order of magnitude higher than the high temperature components. The high density plasma may exist in the cavity wall where it equilibrates rapidly and cools efficiently. The low density plasma is in...

  18. Contemporary developments in the discovery of selective factor Xa inhibitors: A review.

    Science.gov (United States)

    Patel, Nirav R; Patel, Dushyant V; Murumkar, Prashant R; Yadav, Mange Ram

    2016-10-01

    Thrombosis is a leading cause of death in cardiovascular diseases such as myocardial infarction (MI), unstable angina and acute coronary syndrome (ACS) in the industrialized world. Venous thromboembolism is observed in about 1 million people every year in United States causing significant morbidity and mortality. Conventional antithrombotic therapy has been reported to have several disadvantages and limitations like inconvenience in oral administration, bleeding risks (heparin analogs), narrow therapeutic window and undesirable interactions with food and drugs (vitamin K antagonist-warfarin). The unmet medical demand for orally active safe anticoagulants has generated widespread interest among the medicinal chemists engaged in this field. To modulate blood coagulation, various enzymes involved in the coagulation process have received great attention as potential targets by various research groups for the development of oral anticoagulants. Among these enzymes, factor Xa (FXa) has remained the centre of attention in the last decade. Intensive research efforts have been made by various research groups for the development of small, safe and orally bioavailable FXa inhibitors. This review is an attempt to compile the research work of various researchers in the direction of development of FXa inhibitors reported since 2010 onward. PMID:27322757

  19. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination.

    Science.gov (United States)

    Mendell, Jeanne; Noveck, Robert J; Shi, Minggao

    2012-10-01

    The oral anticoagulant edoxaban, a factor Xa inhibitor, will likely be coadministered with digoxin in some patients with atrial fibrillation. Both drugs are substrates for P-glycoprotein. The objective of this phase 1, parallel study was to assess the effects of coadministration of both drugs on their respective pharmacokinetics (PK) and pharmacodynamics (PD). Forty-eight subjects, aged 18 to 45 years, received either edoxaban 60 mg once daily × 7 days (n = 24) or digoxin 0.25 mg twice daily × 2 days and once daily × 5 days (n = 24) and then concomitantly for 7 days. Serial blood and urine samples were collected for digoxin and edoxaban concentrations on days 7 and 14. Serial coagulation assays were measured for edoxaban on days 7 and 14. Edoxaban PK parameters demonstrated mild increases in area under the curve and peak concentrations of 9.5% and 15.6%, respectively, when coadministered with digoxin. Although digoxin PK parameters demonstrated increased area under the curve and peak concentrations of 8.3% and 28%, respectively, plasma concentrations were within the established therapeutic range. Edoxaban PD were consistent with PK. Both drugs were well tolerated alone or in combination. No clinically significant changes in PK, PD, or renal elimination were observed with concomitant administration of edoxaban and digoxin. PMID:23064240

  20. Spitzer IRS Observations of the XA Region in the Cygnus Loop Supernova Remnant

    CERN Document Server

    Sankrit, R; Bautista, M; Gaetz, T J; Williams, B J; Blair, W P; Borkowski, K J; Long, K S

    2014-01-01

    We report on spectra of two positions in the XA region of the Cygnus Loop supernova remnant obtained with the InfraRed Spectrograph on the Spitzer Space Telescope. The spectra span the 10-35 micron wavelength range, which contains a number of collisionally excited forbidden lines. These data are supplemented by optical spectra obtained at the Whipple Observatory and an archival UV spectrum from the International Ultraviolet Explorer. Coverage from the UV through the IR provides tests of shock wave models and tight constraints on model parameters. Only lines from high ionization species are detected in the spectrum of a filament on the edge of the remnant. The filament traces a 180 km/s shock that has just begun to cool, and the oxygen to neon abundance ratio lies in the normal range found for Galactic H II regions. Lines from both high and low ionization species are detected in the spectrum of the cusp of a shock-cloud interaction, which lies within the remnant boundary. The spectrum of the cusp region is mat...

  1. Engineering Factor Xa Inhibitor with Multiple Platelet-Binding Sites Facilitates its Platelet Targeting

    Science.gov (United States)

    Zhu, Yuanjun; Li, Ruyi; Lin, Yuan; Shui, Mengyang; Liu, Xiaoyan; Chen, Huan; Wang, Yinye

    2016-01-01

    Targeted delivery of antithrombotic drugs centralizes the effects in the thrombosis site and reduces the hemorrhage side effects in uninjured vessels. We have recently reported that the platelet-targeting factor Xa (FXa) inhibitors, constructed by engineering one Arg-Gly-Asp (RGD) motif into Ancylostoma caninum anticoagulant peptide 5 (AcAP5), can reduce the risk of systemic bleeding than non-targeted AcAP5 in mouse arterial injury model. Increasing the number of platelet-binding sites of FXa inhibitors may facilitate their adhesion to activated platelets, and further lower the bleeding risks. For this purpose, we introduced three RGD motifs into AcAP5 to generate a variant NR4 containing three platelet-binding sites. NR4 reserved its inherent anti-FXa activity. Protein-protein docking showed that all three RGD motifs were capable of binding to platelet receptor αIIbβ3. Molecular dynamics simulation demonstrated that NR4 has more opportunities to interact with αIIbβ3 than single-RGD-containing NR3. Flow cytometry analysis and rat arterial thrombosis model further confirmed that NR4 possesses enhanced platelet targeting activity. Moreover, NR4-treated mice showed a trend toward less tail bleeding time than NR3-treated mice in carotid artery endothelium injury model. Therefore, our data suggest that engineering multiple binding sites in one recombinant protein is a useful tool to improve its platelet-targeting efficiency. PMID:27432161

  2. Engineering Factor Xa Inhibitor with Multiple Platelet-Binding Sites Facilitates its Platelet Targeting.

    Science.gov (United States)

    Zhu, Yuanjun; Li, Ruyi; Lin, Yuan; Shui, Mengyang; Liu, Xiaoyan; Chen, Huan; Wang, Yinye

    2016-01-01

    Targeted delivery of antithrombotic drugs centralizes the effects in the thrombosis site and reduces the hemorrhage side effects in uninjured vessels. We have recently reported that the platelet-targeting factor Xa (FXa) inhibitors, constructed by engineering one Arg-Gly-Asp (RGD) motif into Ancylostoma caninum anticoagulant peptide 5 (AcAP5), can reduce the risk of systemic bleeding than non-targeted AcAP5 in mouse arterial injury model. Increasing the number of platelet-binding sites of FXa inhibitors may facilitate their adhesion to activated platelets, and further lower the bleeding risks. For this purpose, we introduced three RGD motifs into AcAP5 to generate a variant NR4 containing three platelet-binding sites. NR4 reserved its inherent anti-FXa activity. Protein-protein docking showed that all three RGD motifs were capable of binding to platelet receptor αIIbβ3. Molecular dynamics simulation demonstrated that NR4 has more opportunities to interact with αIIbβ3 than single-RGD-containing NR3. Flow cytometry analysis and rat arterial thrombosis model further confirmed that NR4 possesses enhanced platelet targeting activity. Moreover, NR4-treated mice showed a trend toward less tail bleeding time than NR3-treated mice in carotid artery endothelium injury model. Therefore, our data suggest that engineering multiple binding sites in one recombinant protein is a useful tool to improve its platelet-targeting efficiency. PMID:27432161

  3. Production of Transgenic Anliucheng Sweet Orange (Citrus sinensis Osbeck) with Xa21 Gene for Potential Canker Resistance

    Institute of Scientific and Technical Information of China (English)

    LI Ding-li; XIAO Xuan; and GUO Wen-wu

    2014-01-01

    Citrus canker, an epidemic quarantine disease caused by Xanthomonas axonopodis pv. citri, has brought a great damage in citrus production worldwide. Herein, a rice PRR (pattern recognition receptor) gene Xa21 together with GUS reporter gene and hygromycin phosphotransferase gene (HPT) was introduced into Anliucheng sweet orange (Citrus sinensis Osbeck) via Agrobacterium-mediated transformation of embryogenic callus. The transgenic calluses were screened on MT basal medium containing hygromycin (HYG) and detected by histochemical GUS staining. The transgenic plantlets were recovered through somatic embryogenesis pathway. The regenerated plantlets were accustomed to and maintained in the greenhouse. The transgene integration of recovered plantlets was identiifed by PCR and Southern blot hybridization. It showed that all the transgenic plantlets tested had undergone single copy integration, the expression of Xa21 in eight different transgenic lines detected by qRT-PCR can be divided into three grades, high for T5 and T6, middle for T4 and low for the rest. The tolerance to citrus canker disease of the three recovered transgenic lines T2, T4 and T6 was assessed by in vitro pin-puncture inoculation. The results showed that all the three transgenic lines conferred improved resistance to citrus canker bacterium infection and the T4 transgenic line displayed the highest resistance. The mechanism and feasibility of rice Xa21 in triggering innate immunity in citrus was brielfy discussed.

  4. Characterization of Xanthomonas oryzae-Responsive cis-Acting Element in the Promoter of Rice Race-Specific Susceptibility Gene Xa13

    Institute of Scientific and Technical Information of China (English)

    Ting Yuan; Xianghua Li; Jinghua Xiao; Shiping Wang

    2011-01-01

    The rice Xa13 gene,whose promoter harbors a UPT (up-regulated by transcription activator-like [TAL] effector) box,UPTPthXo1,plays a pivotal role in the race-specific pathogenicity caused by Xanthomonas oryzae pv. Oryzae (Xoo) strain PXO99. PXO99 causes rice disease by inducing Xa13. It is unknown,however,whether the UPTPthXo1 box is the only PXO99-responsive c/s-regulating elements in the activation of Xa13 expression. We analyzed the expression of a series of end- and site-truncated and site-mutated Xa 13 promoters in rice and the binding of PXO99 protein to the intact,partial,or site-mutated UPTPthXo1 boxes. In the Xa13 promoter,UPTPthXo1 box is the only Xoo-responsive cis-acting element that results in PXO99-induced Xa13 expression. The 5'-terminal second,third,and fourth nucleotides of the box are important for bacterial protein binding and gene activation;mutation of any one of these sites abolished PXO99-induced gene expression. Furthermore,the 3'-half of the UPTPthXo1 box is also required for protein binding and gene activation. These findings will enhance our understanding of the molecular mechanism of the interaction of rice and Xoo via UPT boxes and TAL effectors.

  5. Effects of Xylopia aethiopica (Annonaceae) fruit methanol extract on gamma-radiation-induced oxidative stress in brain of adult male Wistar rats.

    Science.gov (United States)

    Adaramoye, O A; Popoola, Bosede O; Farombi, E O

    2010-09-01

    Xylopia aethiopica (XA) (Annonaceae) possesses great nutritional and medicinal values. This study was designed to investigate the effects of XA fruit methanol extract on oxidative stress in brain of rats exposed to whole body gamma-radiation (5 Gy). Vitamin C (VC) served as standard antioxidant. Forty-four rats were divided into 4 groups of 11 rats each. One group served as control, two different groups were treated with XA and VC (250 mg/kg), 6 weeks before and 8 weeks after irradiation, and fourth group was only irradiated. Rats were sacrificed 1 and 8 weeks after irradiation. The antioxidant status, viz. Lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT), glutathione-s-transferase (GST) and glutathione (GSH) were estimated. Results indicate a significant increase (p < 0.05) in levels of brain LPO after irradiation. LPO increased by 90% and 151%, after 1 and 8 weeks of irradiation, respectively. Irradiation caused significant (p < 0.05) decreases in levels of GSH and GST by 61% and 43% after 1 week and, 75% and 73%, respectively, after 8 weeks of exposure. CAT and SOD levels were decreased by 62% and 68%, respectively, after 8 weeks of irradiation. Treatment with XA and VC ameliorated the radiation-induced decreases in antioxidant status of the animals. These suggest that XA could have beneficial effect by inhibiting oxidative damage in brain of exposed rats.

  6. Spitzer IRS observations of the XA region in the cygnus loop supernova remnant

    Energy Technology Data Exchange (ETDEWEB)

    Sankrit, Ravi [SOFIA Science Center, NASA Ames Research Center, M/S N211-3, Moffett Field, CA 94035 (United States); Raymond, John C.; Gaetz, Terrance J. [Smithsonian Astrophysical Observatory, 60 Garden Street, MS 15, Cambridge, MA 02138 (United States); Bautista, Manuel [Department of Physics, Western Michigan University, Kalamazoo MI 49008-5252 (United States); Williams, Brian J. [Goddard Space Flight Center, Mail Code 662, Greenbelt, MD 20771 (United States); Blair, William P. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Borkowski, Kazimierz J. [North Carolina State University, Raleigh, NC 27607 (United States); Long, Knox S. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2014-05-20

    We report on spectra of two positions in the XA region of the Cygnus Loop supernova remnant obtained with the InfraRed Spectrograph on the Spitzer Space Telescope. The spectra span the 10-35 μm wavelength range, which contains a number of collisionally excited forbidden lines. These data are supplemented by optical spectra obtained at the Whipple Observatory and an archival UV spectrum from the International Ultraviolet Explorer. Coverage from the UV through the IR provides tests of shock wave models and tight constraints on model parameters. Only lines from high ionization species are detected in the spectrum of a filament on the edge of the remnant. The filament traces a 180 km s{sup –1} shock that has just begun to cool, and the oxygen to neon abundance ratio lies in the normal range found for Galactic H II regions. Lines from both high and low ionization species are detected in the spectrum of the cusp of a shock-cloud interaction, which lies within the remnant boundary. The spectrum of the cusp region is matched by a shock of about 150 km s{sup –1} that has cooled and begun to recombine. The post-shock region has a swept-up column density of about 1.3 × 10{sup 18} cm{sup –2}, and the gas has reached a temperature of 7000-8000 K. The spectrum of the Cusp indicates that roughly half of the refractory silicon and iron atoms have been liberated from the grains. Dust emission is not detected at either position.

  7. Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa.

    Science.gov (United States)

    Al-Tamimi, Mohammad; Grigoriadis, George; Tran, Huy; Paul, Eldho; Servadei, Patricia; Berndt, Michael C; Gardiner, Elizabeth E; Andrews, Robert K

    2011-04-01

    This study evaluated shedding of the platelet collagen receptor, glycoprotein VI (GPVI) in human plasma. Collagen or other ligands induce metalloproteinase-mediated GPVI ectodomain shedding, generating approximately 55-kDa soluble GPVI (sGPVI) and approximately 10-kDa platelet-associated fragments. In the absence of GPVI ligands, coagulation of platelet-rich plasma from healthy persons induced GPVI shedding, independent of added tissue factor, but inhibitable by metalloproteinase inhibitor, GM6001. Factor Xa (FXa) common to intrinsic and tissue factor-mediated coagulation pathways was critical for sGPVI release because (1) shedding was strongly blocked by the FXa-selective inhibitor rivaroxaban but not FIIa (thrombin) inhibitors dabigatran or hirudin; (2) Russell viper venom that directly activates FX generated sGPVI, with complete inhibition by enoxaparin (inhibits FXa and FIIa) but not hirudin; (3) impaired GPVI shedding during coagulation of washed platelets resuspended in FX-depleted plasma was restored by adding purified FX; and (4) purified FXa induced GM6001-inhibitable GPVI shedding from washed platelets. In 29 patients with disseminated intravascular coagulation, mean plasma sGPVI was 53.9 ng/mL (95% confidence interval, 39.9-72.8 ng/mL) compared with 12.5 ng/mL (95% confidence interval, 9.0-17.3 ng/mL) in thrombocytopenic controls (n = 36, P coagulation-induced GPVI shedding via FXa down-regulates GPVI under procoagulant conditions. FXa inhibitors have an unexpected role in preventing GPVI down-regulation.

  8. Factor Xa inhibitors: new anti-thrombotic agents and their characteristics.

    Science.gov (United States)

    Ieko, Masahiro; Tarumi, Takashi; Nakabayashi, Toru; Yoshida, Mika; Naito, Sumiyoshi; Koike, Takao

    2006-01-01

    Factor Xa (FXa) is a key enzyme that is positioned at the convergence of the intrinsic and extrinsic pathways in the blood coagulation cascade, and inactivation by a specific FXa inhibitor effectively prevents the generation of thrombin. Various types of low molecular weight (LMW) heparin, which function as semi-selective and indirect FXa inhibitors, are replacing unfractionated heparin (UFH) as agents for the prevention and treatment of venous thromboembolism (VTE), as well as in initial treatment for coronary events. Of those, heparinoid has been shown to be safer and more effective for the prevention of postoperative VTE than UFH, especially for treatment of heparin-induced thrombocytopenia (HIT). Further, synthetic pentasaccharide has been found to offer advantages over current thromboprophylactic regimens in a number of patients undergoing major orthopedic surgery. Other studies have shown that pentasaccharide is more effective for overall VTE in comparison with LMW heparin, though it was also associated with an increased rate of major bleeding. Synthetic, selective, and direct inhibitors to FXa, such as DX-9065a, are highly potent and orally bioavailable antithrombotic agents that have demonstrated an improved side effect profile, probably by allowing sufficient thrombin to remain for platelet activation and normal hemostasis, while preventing pathological thrombus formation. For thrombosis therapy, the most desirable type of antithrombotic agent is an orally active drug that has a broad range of effective doses and no hemorrhagic side effects. Presently, many types of direct inhibitors are in various stages of clinical trials and expected to provide significant benefits as compared to currently utilized therapy strategies. PMID:16146728

  9. Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors.

    Science.gov (United States)

    Zhu, Yuanjun; Lin, Yuan; Liu, Aihua; Shui, Mengyang; Li, Ruyi; Liu, Xiaoyan; Hu, Wenhui; Wang, Yinye

    2015-06-15

    Anticoagulants and anti-platelet agents are simultaneously administrated in clinical practice (i.e. percutaneous coronary intervention), which cause significant risk of systemic bleeding. Targeted delivery of anticoagulants to the activated platelets at sites of vascular injuries may condense the site-specific anticoagulant effect and reduce the hemorrhage side effects in uninjured vessels. To this end, we prepared three ancylostoma caninum anticoagulant peptide 5 (AcAP5) variants NR1, NR2 and NR3 engineered with a platelet-binding Arg-Gly-Asp (RGD) motif and evaluated their anti-Factor Xa (FXa) and platelet-binding effects. These RGD-containing AcAP5 variants were capable of interacting with platelet receptor αIIbβ3 as shown in computational analysis. All variants, especially NR2 and NR3, retained entirely the anti-FXa function of parent AcAP5. Moreover, they prevented the formation of occlusive thrombi in rat carotid artery injury model, suggesting that they inhibit platelet aggregation in vivo. Further functional investigation of NR3 demonstrated that NR3 inhibited platelet aggregation in vitro and FXa activity in vivo, and prolonged the coagulation time, all in a dose-dependent manner. Through flow cytometry assay, we confirmed the binding of NR3 to αIIbβ3 receptor. In mouse model of carotid artery endothelium injury, NR3-treated mice showed less tail bleeding time than AcAP5-treated mice, and aspirin plus NR3 treatment exhibited moderate reduction of blood loss compared with aspirin plus AcAP5 treatment. These results indicate the feasibility to engineer a novel FXa inhibitor specifically targeting the activated platelets, which centralizes its anticoagulation efficacy in the injured vascular endothelium and reduces the risk of systemic bleeding. PMID:25887920

  10. Des-gamma-carboxyprothrombin (PIVKA II) and plasma vitamin K1 in newborns and their mothers.

    Science.gov (United States)

    von Kries, R; Shearer, M J; Widdershoven, J; Motohara, K; Umbach, G; Göbel, U

    1992-10-01

    Assessments of the vitamin K status in newborns and their mothers by means of des-gamma-carboxy-prothrombin (PIVKA II) measurement have given equivocal results. Part of the variability could be attributed to differences in sensitivity (i.e. the ability to detect small concentrations) and validity (i.e. ability to detect vitamin K deficiency) of the methods applied. None of these methods have yet been validated with respect to plasma vitamin K1. In 22 healthy mother/infant pairs PIVKA II was determined using three different assays including ratio Xa/ecarin (Xa/ec), crossed immunoelectrophoresis (CIE), and an ELISA with a monoclonal antibody (MAB). The results were compared with conventional clotting tests and plasma vitamin K1. The following results were obtained: Cord blood: Clotting tests within age-related normal ranges; PIVKA II detection rates: 0/22 (Xa/ec), 1/22 (CIE), 4/22 (MAB); plasma vitamin K1: undetectable in 20/22. Mothers: Clotting tests all within normal range; PIVKA II detection rates: 1/22 (Xa/ec), 0/22 (CIE), 5/22 (MAB); plasma vitamin K1 (pg/ml) for all mothers (median; range): 186; 55-833; for PIVKA II positive mothers: 213; 59-699. PIVKA II detectability in newborns and mothers was not correlated. The results show an increase in sensitivity for PIVKA II detection in the order of MAB > CIE > Xa/ec. Due to the very low plasma vitamin K1 at birth, no correlation was possible between cord PIVKA II detectability and plasma vitamin K1. However, in mothers at term PIVKA II MAB appears to be unrelated to the vitamin K status.

  11. HD-DVD曙光初现——东芝HD-XA1 HD DVD播放机

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    全球首部HD DVD播放机已经推出,它就是TOSHIBA HD—XA1,这也意味蕾HD高;膏视频时代即将来到我们身边。虽然在早期,HD视频相关产品的价格不可避免地的会高高在上,但并不影响我们第一时间对这款划时代的播放机进行评测。

  12. 直接Xa因子抑制剂贝曲沙班%Direct factor Xa inhibitor betrixaban

    Institute of Scientific and Technical Information of China (English)

    王兵; 刘颖; 刘登科; 王平保

    2015-01-01

    心脑血管疾病已成为全球致病和致死率最高的疾病之一,血栓形成是心脑血管疾病的主要诱因。传统的抗凝药物以肝素和华法林为主,但存在出血、血小板减少的明显不良反应。Xa 因子处于内源性凝血和外源性凝血通路的中心位置,并且每分子的Xa因子可活化产生约1000分子的凝血酶,Xa因子抑制剂的出现为抗凝药物的发展提供了新的方向。贝曲沙班是一种口服的直接Xa因子抑制剂,也是目前唯一经肾脏排泄最少的药物,在一系列研究中显示出良好的治疗前景。主要从贝曲沙班的药物概况、相关背景、合成路线、作用机制、临床研究等方面进行介绍。%Cardiovascular and cerebrovascular diseases have become one of the leading causes of morbidity and mortality in the world. Thrombosis is a major cause. Conventional antithrombotic therapy comprises heparin, warfarin, and so on. All these agents have a potential bleeding risk and a significant adverse reaction of thrombocytopenia. Factor Xa, presented at the juncture of the intrinsic and the extrinsic pathways, plays a pivotal role in the blood coagulation cascade, and per molecule produces thrombin approximately 1000 molecules. Factor Xa inhibitors provide a new direction for the development of anticoagnlant drugs. Betrixaban is an oral direct factor Xa inhibitor, and has the lowest renal excretion. In a series of researches, betrixaban shows a good prospect. The drug situation, background, route of synthesis, pharmacological action and clinical trials researches of betrixaban are reviewed in this paper.

  13. AvrXa3:A novel member of avrBs3 gene family from Xanthomonas oryzae pv.oryzae has a dual function

    Institute of Scientific and Technical Information of China (English)

    LI Ping; LONG Juying; HUANG Yingchun; ZHANG Yan; WANG Jinsheng

    2004-01-01

    Two positive clones pUAV45 and pUAV47 were identified from the cDNA library of JxoⅢ, a race 3 strain of Xanthomonas oryzae pv. Oryzae Dye (Xoo) in Japanese system, using Tn5 based technology. pUAV45 clone contained a 25.4 kb Xoo genomic DNA insert. Southern blot analysis with avrXa10 as the probe showed that DNA insert in pUAV45 shares homology with avrX10. Furthermore within the Xoo insert, a smaller 5.7 kb KpnI fragment (pUAVSk) was identified through hybridization with avrXa10. The transformation of pUAV45 and pUAV5k into the strain Pxo99 (race 6 in Philippine system) led to the decrease of Pxo99pathogenicity on rice cultivar Wase Aikoku 3 (Xa3) and the increase of the pathogen pathogenicity on Cas209 (Xa10). The result of sequence analysis showed that there is a 2598 bp open reading frame (ORF) within the 5.7 kb Kpn 1 fragment (pUAVSk). The ORF shared high identity (97 % ) with avrXa10. The deduced sequence of the ORF contained 8.5 tandem repeat units of 34-amino-acids, one leucine zipper (LZ), three nuclear localization signal (NLS) motifs, and an acidic activation transcriptional domain (AAD) at C-terminus.We named this ORF avrXa3 and it is classified as a new member of avrBs3 (avr/pth) family with the dual-function determined by alternations of avirulence and aggressiveness on rice cultivars carrying different ‘ R' genes.

  14. 基于P51XA-S3微机的剑杆织机控制系统%Utilize P51XA-S3 to Design Control System of Microcomputer Rapier Loom

    Institute of Scientific and Technical Information of China (English)

    俞建军

    2011-01-01

    采用飞利浦的16位微机P51XA-S3和大容量在系统存储芯片PSD934设计一种高档的剑杆织机控制器,同时采用实时时钟芯片RS5C372A、看门狗电路IMP706、通信芯片MAX232、75176以及先藕隔离器等器件,保证系统的稳定性与先进性,系统采用C语言编程,采用光电编码器对织机主轴转过的角度进行监控,所设计的系统可支持织机的最高转速可达600r/min.%Using 16-bit microprocessor P51 XA-S3 of Philips and high-capacity in-system memory chips PSD934 to design one kind of high-end controller of rapier loom, the paper adopted devices like real time clock chip RS5C372A, watch-dog circuit IMP706, communication chip MAX232, 75176 and optical coupling isolator, etc. To ensure stability and advancement of system. The system adopts C programming language and photoelectric encoder, etc. To monitor the turning angle of the main shaft of loom. The system designed can support the highest rotational speed of 600 r/min of the loom.

  15. Transgenic expression of the rice Xa21 pattern-recognition receptor in banana (Musa sp.) confers resistance to Xanthomonas campestris pv. musacearum.

    Science.gov (United States)

    Tripathi, Jaindra N; Lorenzen, Jim; Bahar, Ofir; Ronald, Pamela; Tripathi, Leena

    2014-08-01

    Banana Xanthomonas wilt (BXW), caused by the bacterium Xanthomonas campestris pv. musacearum (Xcm), is the most devastating disease of banana in east and central Africa. The spread of BXW threatens the livelihood of millions of African farmers who depend on banana for food security and income. There are no commercial chemicals, biocontrol agents or resistant cultivars available to control BXW. Here, we take advantage of the robust resistance conferred by the rice pattern-recognition receptor (PRR), XA21, to the rice pathogen Xanthomonas oryzae pv. oryzae (Xoo). We identified a set of genes required for activation of Xa21-mediated immunity (rax) that were conserved in both Xoo and Xcm. Based on the conservation, we hypothesized that intergeneric transfer of Xa21 would confer resistance to Xcm. We evaluated 25 transgenic lines of the banana cultivar 'Gonja manjaya' (AAB) using a rapid bioassay and 12 transgenic lines in the glasshouse for resistance against Xcm. About 50% of the transgenic lines showed complete resistance to Xcm in both assays. In contrast, all of the nontransgenic control plants showed severe symptoms that progressed to complete wilting. These results indicate that the constitutive expression of the rice Xa21 gene in banana results in enhanced resistance against Xcm. Furthermore, this work demonstrates the feasibility of PRR gene transfer between monocotyledonous species and provides a valuable new tool for controlling the BXW pandemic of banana, a staple food for 100 million people in east Africa.

  16. Efficient selection of homozy-gous lines of hybrid rice restorer with the transgene Xa21 using test cross and PCR

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The homozygous restorer lines with a single copy of the transgene Xa21 have been obtained from the progenies of transgenic Minghui63 and Yanhui559 plants through PCR marker-assisted selection and test cross. These homozygous transgenic restorer lines can be used to breed hybrid rice with high resistance to bacterial leaf blight.

  17. Measuring the Luminosity of a gamma gamma Collider with gamma gamma -> l+ l- gamma Events

    OpenAIRE

    Makarenko, V.; Moenig, K.; Shishkina, T.

    2003-01-01

    The process gamma gamma -> l+ l- is highly suppressed when the total angular momentum of the two colliding photons is zero so that it cannot be used for luminosity determination. This configuration, however is needed for Higgs production at a photon collider. It will be shown that the process gamma gamma -> l+ l- gamma can be used in this case to measure the luminosity of a collider with a precision that is good enough not to limit the error on the partial decay width Gamma(H -> gamma gamma).

  18. Determination of factor Xa inhibition doses of low-molecular heparin, nadroparin and reviparin in urological patients

    Directory of Open Access Journals (Sweden)

    Pavlović Svetlana

    2007-01-01

    Full Text Available Background/Aim. The inhibition of factor Xa (FX by the use of low-molecular heparin (LMH is important clinical procedure in patients with moderate and high risk for the developament of venous thromboembolism (VTE and pulmonary embolism (PE. The aim of this study was to determine the level of inhibition of FXa by the use of prophylactic doses of LMH nadroparin-calcium and reviparine-sodium which were applied in urological patients with moderate risk for VTE and PE. Methods. The examination included 80 urological patients divided into 4 groups after urological, uroradiological and anesthesiological preoperative preparation and categorization of anesthesiological risk according to the ASA III classification. The first two groups, of 20 patients each, received the recommended doses of LMH in accordance with the preoperative risk, and an inhibition of FXa 48 hours after the surgical operation and four hours after the administration of LMH was determined. Heptest and homogenous anti-Xa test were used for monitoring of FXa inhibition. Since the obtained anti-Xa values were not satisfactory, two more groups were formed and given double the recommended doses. In these new groups, inhibition of FXa was in recommended range. Standard descriptive statistical parameters were used for describing the charateristics of the people from the formed groups. Results. All the patients examined were clinically estimated as patients of moderate risk, for VTE and PE. There were no statistically singificant difference in body weight of the patients who received nadroparin-calcium 0.3 ml and reviparine-sodium 0.25 ml and those who received their double doses, respectively. The level of FXa inhibition in the group in which the dose of nadroparin-calcium of 0.6 ml was applied was statistically significantly higher than in the group which received the dose of 0.3 ml (Mann-Whitney U test: Z = 5.416; p < 0.0001. The level of FXa in the group given reviparine-sodium 0.5 ml was

  19. RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome

    DEFF Research Database (Denmark)

    Steg, Ph Gabriel; Mehta, Shamir R; Jukema, J Wouter;

    2011-01-01

    To establish the safety, tolerability and most promising regimen of darexaban (YM150), a novel, oral, direct factor Xa inhibitor, for prevention of ischaemic events in acute coronary syndrome (ACS)....

  20. MODEL GROUP INVESTIGATION (GI) DIPADU PROBLEM BASED LEARNING (PBL) UNTUK MENINGKATKAN KETERAMPILAN BEKERJA ILMIAH DAN KEMAMPUAN KOGNITIF SISWA KELAS X-A1 SMAN 2 MALANG

    OpenAIRE

    Prasmala, Erfitra Rezqi

    2016-01-01

    ABSTRACTThe purpose of this study to improve (1) the skills of scientific work, (2) the cognitive abilities of students of class X-A1 at SMAN 2 Malang through the application of models Group Investigation (GI) combined with the Problem Based Learning (PBL). Type of research is Action Research Action (PTK) with research subjects-A1 class X SMAN 2 Malang. Data collected by the research instrument consisting of a sheet of observation skills of scientific work, scientific work reports, students' ...

  1. Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

    OpenAIRE

    Mendell, Jeanne; Zahir, Hamim; Matsushima, Nobuko; Noveck, Robert; Lee, Frank; Chen, Shuquan; Zhang, George; Shi, Minggao

    2013-01-01

    Background Edoxaban, an oral direct factor Xa inhibitor, is in development for thromboprophylaxis, including prevention of stroke and systemic embolism in patients with atrial fibrillation (AF). P-glycoprotein (P-gp), an efflux transporter, modulates absorption and excretion of xenobiotics. Edoxaban is a P-gp substrate, and several cardiovascular (CV) drugs have the potential to inhibit P-gp and increase drug exposure. Objective To assess the potential pharmacokinetic interactions of edoxaban...

  2. Edoxaban: A Novel Factor Xa Inhibitor for the Management of Non-valvular Atrial Fibrillation and Venous Thromboembolism.

    Science.gov (United States)

    Kubli, Kara A; Snead, Jessica A; Cheng-Lai, Angela

    2016-01-01

    Warfarin has been a highly prevalent agent for over 70 years; however, its use has been limited by drug-drug interactions, adverse events, and the need for frequent monitoring. To minimize these complications, several non-vitamin K oral anticoagulants have been approved, including the latest agent, edoxaban. Edoxaban is a factor Xa inhibitor approved for the prevention of stroke/systemic embolism in patients with non-valvular atrial fibrillation and for the treatment of venous thromboembolism. Edoxaban was largely studied in the Edoxaban versus Warfarin in Patients with Atrial Fibrillation (ENGAGE AF-TIMI 48) and Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism (Hokusai-VTE) trials, both showing noninferiority when compared with warfarin. Similar to other oral anticoagulants, the most serious adverse effects of edoxaban are related to bleeding. However, there are currently no approved reversal agents. Andexanet alfa and ciraparantag are the latest agents being studied for reversal. This article provides an overview of the safety and efficacy along with the advantages and disadvantages of edoxaban. PMID:26991962

  3. Microfluidic Chip-Based Online Screening Coupled to Mass Spectrometry: Identification of Inhibitors of Thrombin and Factor Xa.

    Science.gov (United States)

    Iyer, Janaki Krishnamoorthy; Otvos, Reka A; Kool, Jeroen; Kini, R Manjunatha

    2016-02-01

    Thrombin and factor Xa (FXa) are critical enzymes of the blood coagulation cascade and are excellent targets of anticoagulant agents. Natural sources present an array of anticoagulants that can be developed as antithrombotic drugs. High-resolution, online screening techniques have been developed for the identification of drug leads from complex mixtures. In this study, we have developed and optimized a microfluidic online screening technique coupled to nano-liquid chromatography (LC) and in parallel with a mass spectrometer for the identification of thrombin and FXa inhibitors in mixtures. Inhibitors eluting from the nano-LC were split postcolumn in a 1:1 ratio; half was fed into a mass spectrometer (where its mass is detected), and the other half was fed into a microfluidic chip (which acts as a microreactor for the online assays). With our platform, thrombin and FXa inhibitors were detected in the assay in parallel with their mass identification. These methods are suitable for the identification of inhibitors from sample amounts as low as sub-microliter volumes. PMID:26323281

  4. Development of a fluorescent anti-factor Xa assay to monitor unfractionated and low molecular weight heparins.

    Science.gov (United States)

    Harris, Leanne F; Castro-López, Vanessa; Hammadi, Nissrin; O'Donnell, James S; Killard, Anthony J

    2010-06-15

    Fluorogenic assays have many potential advantages over traditional clot-based and chromogenic assays such as the absence of interference from a range of factor deficiencies as well as offering the possibility of assays in platelet rich plasma or whole blood. A fluorogenic anti-factor Xa (anti-FXa) assay has been developed for the determination of unfractionated heparin (UFH), low molecular weight heparins (LMWHs), namely enoxaparin and tinzaparin, and the synthetic heparinoid danaparoid, in commercial human pooled plasma. The assay was based on the complexation of heparin-spiked plasmas with exogenous FXa at a concentration of 4nM in the presence of 0.9microM of the fluorogenic substrate methylsulfonyl-D-cyclohexylalanyl-glycyl-arginine-7-amino-4-methylcoumarin acetate (Pefafluor FXa). Pooled plasma samples were spiked with concentrations of anticoagulants in the range 0-1.6U/ml. The assay was capable of the measurement of UFH and danaparoid in the range 0-1U/ml, and enoxaparin and tinzaparin in the range 0-0.8 and 0-0.6U/ml, respectively. Correlation coefficients generated by linear regression of the log/lin data analysis were between 0.93 and 0.96 for the anticoagulants tested. Assay percentage coefficients of variation were typically below 7%. PMID:20441964

  5. AutoGPA-Based 3D-QSAR Modeling and Molecular Docking Study on Factor Xa Inhibitors as Anticoagulant Agents

    Directory of Open Access Journals (Sweden)

    Guo Fang Yuan

    2016-01-01

    Full Text Available The three-dimensional-quantitative structure activity relationship (3D-QSAR studies were performed on a series of direct factor Xa (FXa inhibitors using AutoGPA-based modeling method in this paper. A training set of 38 molecules and a test set containing 10 molecules were used to build the 3D-QSAR model and validate the derived model, respectively. The developed model with correlation coefficients (r2 of 0.8564 and cross-validated correlation coefficients (q2 of 0.6721 were validated by an external test set of 10 molecules with predicted correlation coefficient (rpred2 of 0.6077. Docking study of FXa inhibitors and FXa active site was performed to check the induced pharmacophore query and comparative molecular field analysis (CoMFA contour maps using MOE2012.10. It was proved to be coincidence with the interaction information between ligand and FXa active site and was rendered to provide a useful tool to improve FXa inhibitors.

  6. Gamma watermarking

    Science.gov (United States)

    Ishikawa, Muriel Y.; Wood, Lowell L.; Lougheed, Ronald W.; Moody, Kenton J.; Wang, Tzu-Fang

    2004-05-25

    A covert, gamma-ray "signature" is used as a "watermark" for property identification. This new watermarking technology is based on a unique steganographic or "hidden writing" digital signature, implemented in tiny quantities of gamma-ray-emitting radioisotopic material combinations, generally covertly emplaced on or within an object. This digital signature may be readily recovered at distant future times, by placing a sensitive, high energy-resolution gamma-ray detecting instrument reasonably precisely over the location of the watermark, which location may be known only to the object's owner; however, the signature is concealed from all ordinary detection means because its exceedingly low level of activity is obscured by the natural radiation background (including the gamma radiation naturally emanating from the object itself, from cosmic radiation and material surroundings, from human bodies, etc.). The "watermark" is used in object-tagging for establishing object identity, history or ownership. It thus may serve as an aid to law enforcement officials in identifying stolen property and prosecuting theft thereof. Highly effective, potentially very low cost identification-on demand of items of most all types is thus made possible.

  7. Gamma watermarking

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Muriel Y.; Wood, Lowell L.; Lougheed, Ronald W.; Moody, Kenton J.; Wang, Tzu-Fang

    2004-05-25

    A covert, gamma-ray "signature" is used as a "watermark" for property identification. This new watermarking technology is based on a unique steganographic or "hidden writing" digital signature, implemented in tiny quantities of gamma-ray-emitting radioisotopic material combinations, generally covertly emplaced on or within an object. This digital signature may be readily recovered at distant future times, by placing a sensitive, high energy-resolution gamma-ray detecting instrument reasonably precisely over the location of the watermark, which location may be known only to the object's owner; however, the signature is concealed from all ordinary detection means because its exceedingly low level of activity is obscured by the natural radiation background (including the gamma radiation naturally emanating from the object itself, from cosmic radiation and material surroundings, from human bodies, etc.). The "watermark" is used in object-tagging for establishing object identity, history or ownership. It thus may serve as an aid to law enforcement officials in identifying stolen property and prosecuting theft thereof. Highly effective, potentially very low cost identification-on demand of items of most all types is thus made possible.

  8. Gamma camera

    International Nuclear Information System (INIS)

    The design of a collimation system for a gamma camera for use in nuclear medicine is described. When used with a 2-dimensional position sensitive radiation detector, the novel system can produce superior images than conventional cameras. The optimal thickness and positions of the collimators are derived mathematically. (U.K.)

  9. Daboxin P, a Major Phospholipase A2 Enzyme from the Indian Daboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity

    Science.gov (United States)

    Iyer, Janaki Krishnamurthy; Shih, Norrapat; Majumder, Munmi; Mattaparthi, Venkata Satish Kumar; Mukhopadhyay, Rupak; Doley, Robin

    2016-01-01

    In the present study a major protein has been purified from the venom of Indian Daboia russelii russelii using gel filtration, ion exchange and Rp-HPLC techniques. The purified protein, named daboxin P accounts for ~24% of the total protein of the crude venom and has a molecular mass of 13.597 kDa. It exhibits strong anticoagulant and phospholipase A2 activity but is devoid of any cytotoxic effect on the tested normal or cancerous cell lines. Its primary structure was deduced by N-terminal sequencing and chemical cleavage using Edman degradation and tandem mass spectrometry. It is composed of 121 amino acids with 14 cysteine residues and catalytically active His48 -Asp49 pair. The secondary structure of daboxin P constitutes 42.73% of α-helix and 12.36% of β-sheet. It is found to be stable at acidic (pH 3.0) and neutral pH (pH 7.0) and has a Tm value of 71.59 ± 0.46°C. Daboxin P exhibits anticoagulant effect under in-vitro and in-vivo conditions. It does not inhibit the catalytic activity of the serine proteases but inhibits the activation of factor X to factor Xa by the tenase complexes both in the presence and absence of phospholipids. It also inhibits the tenase complexes when active site residue (His48) was alkylated suggesting its non-enzymatic mode of anticoagulant activity. Moreover, it also inhibits prothrombinase complex when pre-incubated with factor Xa prior to factor Va addition. Fluorescence emission spectroscopy and affinity chromatography suggest the probable interaction of daboxin P with factor X and factor Xa. Molecular docking analysis reveals the interaction of the Ca+2 binding loop; helix C; anticoagulant region and C-terminal region of daboxin P with the heavy chain of factor Xa. This is the first report of a phospholipase A2 enzyme from Indian viper venom which targets both factor X and factor Xa for its anticoagulant activity. PMID:27089306

  10. Daboxin P, a Major Phospholipase A2 Enzyme from the Indian Daboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity.

    Directory of Open Access Journals (Sweden)

    Maitreyee Sharma

    Full Text Available In the present study a major protein has been purified from the venom of Indian Daboia russelii russelii using gel filtration, ion exchange and Rp-HPLC techniques. The purified protein, named daboxin P accounts for ~24% of the total protein of the crude venom and has a molecular mass of 13.597 kDa. It exhibits strong anticoagulant and phospholipase A2 activity but is devoid of any cytotoxic effect on the tested normal or cancerous cell lines. Its primary structure was deduced by N-terminal sequencing and chemical cleavage using Edman degradation and tandem mass spectrometry. It is composed of 121 amino acids with 14 cysteine residues and catalytically active His48 -Asp49 pair. The secondary structure of daboxin P constitutes 42.73% of α-helix and 12.36% of β-sheet. It is found to be stable at acidic (pH 3.0 and neutral pH (pH 7.0 and has a Tm value of 71.59 ± 0.46°C. Daboxin P exhibits anticoagulant effect under in-vitro and in-vivo conditions. It does not inhibit the catalytic activity of the serine proteases but inhibits the activation of factor X to factor Xa by the tenase complexes both in the presence and absence of phospholipids. It also inhibits the tenase complexes when active site residue (His48 was alkylated suggesting its non-enzymatic mode of anticoagulant activity. Moreover, it also inhibits prothrombinase complex when pre-incubated with factor Xa prior to factor Va addition. Fluorescence emission spectroscopy and affinity chromatography suggest the probable interaction of daboxin P with factor X and factor Xa. Molecular docking analysis reveals the interaction of the Ca+2 binding loop; helix C; anticoagulant region and C-terminal region of daboxin P with the heavy chain of factor Xa. This is the first report of a phospholipase A2 enzyme from Indian viper venom which targets both factor X and factor Xa for its anticoagulant activity.

  11. Gamma-ray methods

    International Nuclear Information System (INIS)

    Bulk analysis techniques using gamma radiation are described. The methods include gamma-ray induced reactions, selective gamma-ray scattering and methods which rely on natural radioactivity. The gamma-ray resonance scattering technique can be used for the determination of copper and nickel in bulk samples and drill cores. The application of gamma-gamma methods to iron ore analysis is outlined

  12. [Surgery and invasive procedures in patients on long-term treatment with oral direct thrombin or factor Xa inhibitors].

    Science.gov (United States)

    Sié, P; Samama, C-M; Godier, A; Rosencher, N; Steib, A; Llau, J-V; van der Linden, P; Pernod, G; Lecompte, T; Gouin-Thibault, I; Albaladejo, P

    2011-09-01

    Direct oral anticoagulants (DOAs), inhibitors of factor IIa or Xa, are expected to replace vitamin K antagonists in most of their indications. It is likely that patients on long-term treatment with DOAs will be exposed to elective or emergency surgery or invasive procedures. Due to the present lack of experience in such conditions, we cannot make recommendations, but only propose perioperative management for optimal safety as regards the risk of bleeding and thrombosis. DOAs may increase surgical bleeding, they have no validated antagonists, they cannot be monitored by simple, standardised laboratory assays, and their pharmacokinetics vary significantly from patient to patient. Although DOAs differ in many respects, the proposals in the perioperative setting need not be specific to each. For procedures with low risk of haemorrhage, a therapeutic window of 48 h (last administration 24h before surgery, restart 24h after) is proposed. For procedures with medium or high haemorrhagic risk, we suggest stopping DOAs 5 days before surgery to ensure complete elimination of the drug in all patients. The treatment should be resumed only when the risk of bleeding has been controlled. In patients with a high risk of thrombosis (e.g. those in atrial fibrillation with an antecedent of stroke), bridging with heparin (low molecular weight, or unfractionated if the former is contraindicated) is proposed. In emergency, the procedure should be postponed for as long as possible (minimum 1-2 half-lives) and non-specific anti-haemorrhagic agents, such as recombinant human activated factor VIIa, or prothrombin concentrates, should not be given for prophylactic reversal, due to their uncertain benefit-risk. PMID:21820844

  13. GARCH Gamma

    OpenAIRE

    Robert F. Engle; Joshua V. Rosenberg

    1995-01-01

    This paper addresses the issue of hedging option positions when the underlying asset exhibits stochastic volatility. By parameterizing the volatility process as GARCH, and utilizing risk- neutral valuation, we estimate hedging parameters (delta and gamma) using Monte-Carlo simulation. We estimate hedging parameters for options on the Standard and Poor's 500 index, a bond futures index, a weighted foreign exchange rate index, and an oil futures index. We find that Black-Scholes and GARCH delta...

  14. Gamma teletopography

    International Nuclear Information System (INIS)

    The mapping of gamma sources radiation emission in a nuclear plant is an important safety point. A remote gamma ray mapping process was developed in SPS/CEA/SACLAY. It uses the ''pinhole camera'' principle, precursor of photography. It mainly consists of a radiation proof box, with a small orifice, containing sensitive emulsions at the opposite. A first conventional photographic type emulsion photographs the area. A second photographic emulsion shows up the gamma radiations. The superim position of the two shots gives immediate informations of the precise location of each source of radiation in the observed area. To make easier the presentation and to improve the accuracy of the results for radiation levels mapping, the obtained films are digitally processed. The processing assigns a colours scale to the various levels of observed radiations. Taking account physical data and standard parameters, it gets possible to estimate the dose rate. The device is portable. Its compactness and fully independent nature make it suitable for use anywhere. It can be adapted to a remote automatic handling system, robot... so as to avoid all operator exposure when the local dose rate is too high

  15. X and gamma rays irradiation tests for evaluating performances of Italian dosimetry services

    International Nuclear Information System (INIS)

    The ENEA (Italian Agency for New Technologies, Energy and the Environment)-EDP Group (Personal Dosimetry Experts) has already evaluated the reliability of more than 50% of the 70 Italian personal dosimetry services, which agreed to test their dosimeters through X and gamma irradiation in air. Film,TL and both film and TL are used as detectors. The X and gamma rays energy ranges from 30 keV to 1.250 keV (beam defined by ISO 4037). Exposures range from 5.2 10-6 C/kg to 1.3 10-3 C/kg. Some dosimeters have been irradiated with a single energy level and others with two energy levels. For each one of the nearly 4.000 dosimeters already tested, the ratio R has been calculated: R = Xv/Xa where: Xv is the exposure evaluated by the service, Xa is the actual exposure. The R distributions have been analysed for the dosimeters using film or TL as detectors, as a function of irradiation energy and as a function of exposure values. The results obtained by all tested services are commented. Separate comments deal also with possible reasons of the failures to pass the tests

  16. CP1H-XA40CDR-A可编程器内置模拟量功能在制冷试验装置中应用%The Built-in Analog Functions of CP1H-XA40CDR-A Programmable Used in the Refrigeration Test Device

    Institute of Scientific and Technical Information of China (English)

    杨厚太; 郝颖磊

    2011-01-01

    主要介绍CP1H-XA40CDR-A可编程控制器的内置模拟量输入功能在制冷试验装置中的应用,着重介绍模拟量输入在恒温水箱上的应用,模拟输出在控制无级冷水机组上的应用以及编程时候需要注意的事项。%This article mainly introduces the CP1H-XA40CDR-A built-in analog input capability of programmable logic controller application in refrigeration test equipment,focuses on analog input application in thermostat water tank,analog output in controlled stepless chiller applications,and programming time on matters requiring attention.

  17. Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X

    Energy Technology Data Exchange (ETDEWEB)

    Tee, Meng Kian; Thomson, A.A.; Bristow, J.; Miller, W.L. [Univ. of California, San Francisco, CA (United States)

    1995-07-20

    A compact region in the human class III major histocompatibility locus contains the human genes for the fourth component of human complement (C4) and steroid 21-hydroxylase (P450c21) in one transcriptional orientation, while the gene for the extracellular matrix protein tenascin-X (TN-X) overlaps the last exon of P450c21 on the opposite strand of DNA in the opposite transcriptional orientation. This complex locus is duplicated into A and B loci, so that the organization is 5{prime}-C4A-21A-XA-C4B-21B-XB-3{prime}. Although this duplication event truncated the 65-kb X(B) gene to a 4.5-kb XA gene, the XA gene is transcriptionally active in the adrenal cortex. To examine the basis of the tissue-specific expression of XA and C4B, we cloned the 1763-bp region that lies between the cap sites for XA and C4B and analyzed its promoter activity in both the XA and the C4 orientations. Powerful, liver-specific sequences lie within the first 75 to 138 bp from the C4B cap site, and weaker elements lie within 128 bp of the XA cap site that function in both liver and adrenal cells. Because these 128 bp upstream from the XA cap site are perfectly preserved in the XB gene encoding TN-X, we sought to determine whether a transcript similar to XA arises within the SB gene. RNase protection assays, cDNA cloning, and RT/PCR show that adrenal cells contain a novel transcript, termed short XB (XB-S), which has the same open reading frame as TN-X. Cell-free translation and immunoblotting show that this transcript encodes a novel 74-kDa XB-S protein that is identical to the carboxy-terminal 673 residues of TN-X. Because this protein consists solely of fibronectin type III repeats and a fibrinogen-like domain, it appears to correspond to an evolutionary precursor of the tenascin family of extracellular matrix proteins. 40 refs., 6 figs.

  18. Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2)

    DEFF Research Database (Denmark)

    Eriksson, B I; Turpie, A G G; Lassen, M R;

    2010-01-01

    , 60 or 120 mg) (double-blind) or preoperative subcutaneous (open label) enoxaparin (40 mg) for 5 weeks. The primary efficacy endpoint comprised VTE diagnosed by mandatory bilateral venography or verified symptomatic deep vein thrombosis (DVT) plus all deaths up to 9 days after surgery. The primary......BACKGROUND: Anticoagulant prophylaxis substantially reduces the risk of venous thromboembolism (VTE) after major orthopedic surgery. The direct factor Xa inhibitor YM150 is currently under investigation for the prevention of VTE, stroke and ischemic vascular events in patients after orthopedic...

  19. Fuzzy Gamma-hypersemigroups

    OpenAIRE

    R. Ameri; Sadeghi, R.

    2013-01-01

    We introduced and study fuzzy gamma-hypersemigroups, according to fuzzy semihyper- groups as previously defined [33] and prove that results in this respect. In this regard first we introduce fuzzy hyperoperation and then study fuzzy gamma-hypersemigroup. We will proceed by study fuzzy gamma-hyperideals and fuzzy gamma-bihyperideals. Also we study the relation between the classes of fuzzy gamma-hypersemigroups and semigroups. Precisely, we associate a gamma-hypersemigroup to every fuzzy hypers...

  20. On semi-exclusive measurement of $\\gamma\\gamma\\to\\gamma\\gamma$ scattering

    CERN Document Server

    Staszewski, Rafał

    2016-01-01

    The two-photon production of photon pairs, i.e. the $\\gamma\\gamma\\to\\gamma\\gamma$ process, is studied. Different production modes regarding the elastic or inelastic coupling of the intermediate-state photons to the protons are considered. The semi-exclusive measurement, where one intact proton is registered by a dedicated forward proton detector, is discussed. As an example, the signal and background simulations are performed for the $\\gamma\\gamma\\to\\gamma\\gamma$ process mediated by the hypothetical 750 GeV resonance.

  1. GAMMA-400 gamma-ray observatory

    CERN Document Server

    Topchiev, N P; Bonvicini, V; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bakaldin, A V; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, L; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Cumani, P; Dalkarov, O D; Dedenko, G L; De Donato, C; Dogiel, V A; Finetti, N; Gascon, D; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Martinez, M; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Paredes, J M; Pearce, M; Picozza, P; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Stozhkov, Yu I; Suchkov, S I; Taraskin, A A; Tavani, M; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Ward, J E; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    The GAMMA-400 gamma-ray telescope with excellent angular and energy resolutions is designed to search for signatures of dark matter in the fluxes of gamma-ray emission and electrons + positrons. Precision investigations of gamma-ray emission from Galactic Center, Crab, Vela, Cygnus, Geminga, and other regions will be performed, as well as diffuse gamma-ray emission, along with measurements of high-energy electron + positron and nuclei fluxes. Furthermore, it will study gamma-ray bursts and gamma-ray emission from the Sun during periods of solar activity. The energy range of GAMMA-400 is expected to be from ~20 MeV up to TeV energies for gamma rays, up to 20 TeV for electrons + positrons, and up to 10E15 eV for cosmic-ray nuclei. For high-energy gamma rays with energy from 10 to 100 GeV, the GAMMA-400 angular resolution improves from 0.1{\\deg} to ~0.01{\\deg} and energy resolution from 3% to ~1%; the proton rejection factor is ~5x10E5. GAMMA-400 will be installed onboard the Russian space observatory.

  2. Modulation gamma resonance spectroscopy

    International Nuclear Information System (INIS)

    Possibility to control dynamic processes in a matter through gamma-resonance modulation by high-frequency external variable fields in excess of inverse lifetimes of the Moessbauer nuclei excited states, that is, within the megahertz frequency range lies in the heart of the modulation gamma-resonance spectroscopy. Through the use of the gamma-resonance process theoretical analysis methods and of the equation solution method for the density matrix with the secondary quantization of gamma-radiation field one attacks the problems dealing with the effect of both variable fields and relaxation on gamma-resonance. One has studied the gamma-radiation ultrasound modulation stages. One points out a peculiar role of the gamma-magnetic resonance effect in modulation gamma resonance spectroscopy formation. One forecasts development of the modulation gamma-resonance spectroscopy into the nonlinear gamma-resonance spectroscopy

  3. Sequence analysis of Xa21 gene promoter in rice (Oryza sativa ‘Nipponbare')and its expression characteristics under different conditions%水稻Xa21基因启动子序列分析及其在不同条件下的表达特征

    Institute of Scientific and Technical Information of China (English)

    牟少亮; 刘志钦; 赖燕; 蔡汉阳; 何水林

    2012-01-01

    以水稻品种‘日本晴’(Oryza sativa‘ Nipponbare’)为实验材料,根据GenBank上公布的同品种水稻的基因组DNA序列设计1对引物,对水稻Xa21基因启动子进行克隆并测序,通过PCR扩增获得的Xa21基因启动子序列长1 982 bp,其中除包含启动子基本元件外,还包含一些与逆境信号相关的元件(GCC-box、A-box、TC-rich repeats、MBS、LTR和W-box等).利用GUS组织化学染色和定量分析方法,研究了转基因水稻T1代株系不同器官和发育阶段Xa21基因启动子的表达特异性及其在不同逆境和激素处理条件下的表达特征,结果显示:在转基因水稻的叶、茎和根部均能检测到GUS活性,但根部GUS活性最高,特别是在根尖的中柱区活性最强;随苗龄增长(3叶期、5叶期和8至9叶期)叶片中GUS活性逐渐增加,8至9叶期GUS活性最高;机械损伤和100 μmol ·L-1茉莉酸甲酯(MeJA)处理可使叶片中GUS活性显著或极显著提高,而干旱、500 μmol·L-1水杨酸(SA)和100 μmol·L-1脱落酸(ABA)处理则对叶片中GUS活性无明显影响.研究结果表明:外界逆境胁迫对水稻Xa21基因启动子的表达有诱导作用;该启动子的表达受水稻发育阶段的调控并具有一定的器官组织特异性,在根中的表达量最高;其介导的抗病反应依赖于茉莉酸(JA)信号通路.%Taking cultivar' Nipponbare' of rice (Oryza sativa L.) as the experimental materials, Xa21 gene promoter was cloned and sequenced by a pair of primers designed on the basis of genomic DNA sequence of same cultivar published on GenBank.Xa21 gene promoter with sequence length of 1 982 bp is obtained by PCR amplification, in which, except with promoter basic elements, it also contains some elements related to stress signals, such as GCC-box, A-box, TC-rich repeats, MBS, LTR and W-box, etc.By means of GUS histochemical staining and quantitative assay methods, expression specificity of Xa21 gene promoter in different organs and

  4. Rehabilitation of gamma

    Science.gov (United States)

    Poynton, Charles A.

    1998-07-01

    Gamma characterizes the reproduction of tone scale in an imaging system. Gamma summarizes, in a single numerical parameter, the nonlinear relationship between code value--in an 8-bit system, from 0 through 255--and physical intensity. Nearly all image coding systems are nonlinear, and so involve values of gamma different from unity. Owing to poor understanding of tone scale reproduction, and to misconceptions about nonlinear coding, gamma has acquired a terrible reputation in computer graphics and image processing. In addition, the world-wide web suffers from poor reproduction of grayscale and color images, due to poor handling of nonlinear image coding. This paper aims to make gamma respectable again.

  5. Reactor gamma spectrometry: status

    International Nuclear Information System (INIS)

    Current work is described for Compton Recoil Gamma-Ray Spectrometry including developments in experimental technique as well as recent reactor spectrometry measurements. The current status of the method is described concerning gamma spectromoetry probe design and response characteristics. Emphasis is given to gamma spectrometry work in US LWR and BR programs. Gamma spectrometry in BR environments are outlined by focussing on start-up plans for the Fast Test Reactor (FTR). Gamma spectrometry results are presented for a LWR pressure vessel mockup in the Poolside Critical Assembly (PCA) at Oak Ridge National Laboratory

  6. GammaWorkshops Proceedings

    DEFF Research Database (Denmark)

    Strålberg, Elisabeth; Klemola, Seppo; Nielsen, Sven Poul;

    Due to a sparse interaction during the last years between practioners in gamma ray spectrometry in the Nordic countries, a NKS activity was started in 2009. This GammaSem was focused on seminars relevant to gamma spectrometry. A follow up seminar was held in 2010. As an outcome of these activities...... it was suggested that the 2011 meeting should be focused on practical issues, e.g. different corrections needed in gamma spectrometric measurements. This three day’s meeting, GammaWorkshops, was held in September at Risø-DTU. Experts on different topics relevant for gamma spectrometric measurements were invited...... to the GammaWorkshops. The topics included efficiency transfer, true coincidence summing corrections, self-attenuation corrections, measurement of natural radionuclides (natural decay series), combined measurement uncertainty calculations, and detection limits. These topics covered both lectures and practical...

  7. Development of clinical research on apixaban, an oral direct inhibitor of factor Xa%口服Xa因子直接抑制剂阿哌沙班的临床研究进展

    Institute of Scientific and Technical Information of China (English)

    王磊; 钟静芬; 时惠麟

    2012-01-01

      As an oral direct inhibitor of factor Xa, Apixaban is approved after dabigatran etexilate and rivaroxaban, which has been used for prevention of venous thromboembolic events in adult patients who have undergone elective hip or knee replacement surgery. This article discusses the discovery, mechanism, pharmacokinetics, and clinical trials of this emerging drug.%  阿哌沙班是口服 Xa 因子直接抑制剂,继达比加群酯和利伐沙班后上市,用于择期髋关节或膝关节置换手术的成年患者,以预防静脉血栓形成。本文主要介绍这个新药的研发背景、作用机制、药动学和临床试验。

  8. Sur quelques oxydes de cuivre La 1-xA xCuO 3-δ (A = Sr, Y) lacunaires en oxygène et dérivés de la perovskite LaCuO 3

    Science.gov (United States)

    Darracq, S.; Demazeau, G.; Largeteau, A.

    1995-05-01

    LaCuO 3 was the first Cu(III) oxide with the perovskite structure. In 1990, J.F. Bringley et al. described the structures of new non-stoichiometric oxides LaCuO 3-δ. This paper deals with new materials La 1-xA xCuO 3-δ (A = Sr, Y) isostructural with the previous oxides. Their preparation conditions, their stability domain and their physical properties are correlated to the nature of the A cation.

  9. Gamma Splines and Wavelets

    Directory of Open Access Journals (Sweden)

    Hannu Olkkonen

    2013-01-01

    Full Text Available In this work we introduce a new family of splines termed as gamma splines for continuous signal approximation and multiresolution analysis. The gamma splines are born by -times convolution of the exponential by itself. We study the properties of the discrete gamma splines in signal interpolation and approximation. We prove that the gamma splines obey the two-scale equation based on the polyphase decomposition. to introduce the shift invariant gamma spline wavelet transform for tree structured subscale analysis of asymmetric signal waveforms and for systems with asymmetric impulse response. Especially we consider the applications in biomedical signal analysis (EEG, ECG, and EMG. Finally, we discuss the suitability of the gamma spline signal processing in embedded VLSI environment.

  10. Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF)

    DEFF Research Database (Denmark)

    Halperin, Jonathan L; Hankey, Graeme J; Wojdyla, Daniel M;

    2014-01-01

    BACKGROUND: Nonvalvular atrial fibrillation is common in elderly patients, who face an elevated risk of stroke but difficulty sustaining warfarin treatment. The oral factor Xa inhibitor rivaroxaban was noninferior to warfarin in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compar...... younger patients, but the efficacy and safety of rivaroxaban relative to warfarin did not differ with age, supporting rivaroxaban as an alternative for the elderly....

  11. Pharmacokinetics and Pharmacodynamics of Edoxaban, a Non-Vitamin K Antagonist Oral Anticoagulant that Inhibits Clotting Factor Xa.

    Science.gov (United States)

    Parasrampuria, Dolly A; Truitt, Kenneth E

    2016-06-01

    Edoxaban, a once daily non-vitamin K antagonist oral anticoagulant, is a direct, selective, reversible inhibitor of factor Xa (FXa). In healthy subjects, single oral doses of edoxaban result in peak plasma concentrations within 1.0-2.0 h of administration, followed by a biphasic decline. Exposure is approximately dose proportional for once daily doses of 15-150 mg. Edoxaban is predominantly absorbed from the upper gastrointestinal tract, and oral bioavailability is approximately 62 %. Food does not affect total exposure to edoxaban. The terminal elimination half-life in healthy subjects ranges from 10 to 14 h, with minimal accumulation upon repeat once daily dosing up to doses of 120 mg. The steady-state volume of distribution is approximately 107 L, and total clearance is approximately 22 L/h; renal clearance accounts for approximately 50 % of total clearance, while metabolism and biliary secretion account for the remaining 50 %. Intrinsic factors, such as age, sex and race, do not affect edoxaban pharmacokinetics after renal function is taken into account. Oral administration of edoxaban results in rapid changes in anticoagulatory biomarkers, with peak effects on anticoagulation markers (such as anti-FXa), the prothrombin time and the activated partial thromboplastin time occurring within 1-2 h of dosing. PMID:26620048

  12. Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban – an oral, direct Factor Xa inhibitor

    Directory of Open Access Journals (Sweden)

    Rolf eBurghaus

    2014-11-01

    Full Text Available The long-lasting anticoagulant effect of vitamin K antagonists can be problematic in cases of adverse drug reactions or when patients are switched to another anticoagulant therapy. The objective of this study was to examine in silico the anticoagulant effect of rivaroxaban, an oral, direct Factor Xa inhibitor, combined with the residual effect of discontinued warfarin. Our simulations were based on the recommended anticoagulant dosing regimen for stroke prevention in patients with atrial fibrillation. The effects of the combination of discontinued warfarin plus rivaroxaban were simulated using an extended version of a previously validated blood coagulation computer model. A strong synergistic effect of the two distinct mechanisms of action was observed in the first 2–3 days after warfarin discontinuation; thereafter, the effect was close to additive. Nomograms for the introduction of rivaroxaban therapy after warfarin discontinuation were derived for Caucasian and Japanese patients using safety and efficacy criteria described previously, together with the coagulation model. The findings of our study provide a mechanistic pharmacologic rationale for dosing schedules during the therapy switch from warfarin to rivaroxaban and support the switching strategies as outlined in the Summary of Product Characteristics and Prescribing Information for rivaroxaban.

  13. Comparative evaluation of direct thrombin and factor Xa inhibitors with antiplatelet agents under flow and static conditions: an in vitro flow chamber model.

    Directory of Open Access Journals (Sweden)

    Kazuya Hosokawa

    Full Text Available Dabigatran and rivaroxaban are novel oral anticoagulants that specifically inhibit thrombin and factor Xa, respectively. The aim of this study is to elucidate antithrombotic properties of these anticoagulant agents under arterial and venous shear conditions. Whole blood samples treated with dabigatran or rivaroxaban at 250, 500, and 1000 nM, with/without aspirin and AR-C66096, a P2Y12 antagonist, were perfused over a microchip coated with collagen and tissue thromboplastin at shear rates of 240 and 600 s(-1. Fibrin-rich platelet thrombus formation was quantified by monitoring flow pressure changes. Dabigatran at higher concentrations (500 and 1000 nM potently inhibited thrombus formation at both shear rates, whereas 1000 nM of rivaroxaban delayed, but did not completely inhibit, thrombus formation. Dual antiplatelet agents weakly suppressed thrombus formation at both shear rates, but intensified the anticoagulant effects of dabigatran and rivaroxaban. The anticoagulant effects of dabigatran and rivaroxaban were also evaluated under static conditions using thrombin generation (TG assay. In platelet-poor plasma, dabigatran at 250 and 500 nM efficiently prolonged the lag time (LT and moderately reduce peak height (PH of TG, whereas rivaroxaban at 250 nM efficiently prolonged LT and reduced PH of TG. In platelet-rich plasma, however, both anticoagulants efficiently delayed LT and reduced PH of TG. Our results suggest that dabigatran and rivaroxaban may exert distinct antithrombotic effects under flow conditions, particularly in combination with dual antiplatelet therapy.

  14. Peculiaridades da terapia trombolítica na síndrome nefrótica pediátrica: monitorização do fator anti-Xa Particularities of thrombolytic therapy in pediatric nephrotic syndrome: anti-factor Xa monitoring

    Directory of Open Access Journals (Sweden)

    Patrícia Zambi Meirelles

    2008-06-01

    Full Text Available OBJETIVO: Descrever a importância do tromboembolismo pulmonar (TEP na síndrome nefrótica pediátrica e o uso da heparina de baixo peso molecular como opção terapêutica segura e eficaz. DESCRIÇÃO DO CASO: Menino de 5,7 anos com síndrome nefrótica córtico-resistente e glomérulo-esclerose segmentar e focal foi internado devido à diarréia, distúrbios eletrolíticos e anasarca. No 11º dia de internação, evoluiu com desconforto respiratório súbito, cuja investigação mostrou área de alta probabilidade de TEP na cintilografia pulmonar ventilação/perfusão e obstrução em veia jugular interna esquerda ao ultra-som doppler. Iniciado suporte ventilatório com nebulização de oxigênio e anticoagulação com enoxaparina (2mg/kg/dia. Após seis dias, evoluiu com sintomas neurológicos compatíveis com episódio isquêmico transitório, sem alteração na tomografia computadorizada de crânio. A monitorização do fator anti-Xa no soro demonstrou nível subterapêutico e a dose de enoxaparina foi ajustada para 3mg/kg/dia. O edema e os sintomas pulmonares melhoraram e o paciente recebeu alta hospitalar após 33 dias. COMENTÁRIOS: Embora o TEP seja raro em crianças, a síndrome nefrótica é uma condição pró-trombótica que favorece a complicação. A heparina de baixo peso molecular pode ser considerada no tratamento e na profilaxia secundária do TEP, sendo importante monitorizar o nível sérico do fator anti-Xa para ajustar sua dose e promover tratamento seguro e eficaz.OBJECTIVE: Report the importance of pulmonary thromboembolism (PTE in pediatric nephrotic syndrome and the use of low molecular weight heparin (LMWH as an effective and secure therapeutic option. CASE DESCRIPTION: A 5.7 year-old boy with steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis was admitted to the pediatric unit with diarrhea, electrolyte disturbances and anasarca. On the 11th day of hospital stay, he developed a sudden

  15. Beta and Gamma Gradients

    DEFF Research Database (Denmark)

    Løvborg, Leif; Gaffney, C. F.; Clark, P. A.;

    1985-01-01

    Experimental and/or theoretical estimates are presented concerning, (i) attenuation within the sample of beta and gamma radiation from the soil, (ii) the gamma dose within the sample due to its own radioactivity, and (iii) the soil gamma dose in the proximity of boundaries between regions...... of differing radioactivity. It is confirmed that removal of the outer 2 mm of sample is adequate to remove influence from soil beta dose and estimates are made of the error introduced by non-removal. Other evaluations include variation of the soil gamma dose near the ground surface and it appears...

  16. How the $\\gamma \\gamma$ Resonance Stole Christmas

    CERN Document Server

    Craig, Nathaniel; Kilic, Can; Thomas, Scott

    2015-01-01

    The experimental and theoretical implications of heavy di-gauge boson resonances that couple to, or are comprised of, new charged and strongly interacting matter are investigated. Observation and measurement of ratios of the resonant di-gauge boson channels $WW$, $ZZ$, $\\gamma \\gamma$, $Z \\gamma$, and $gg$ in the form of di-jets, provide a rather direct -- and for some ratios a rather robust -- probe of the gauge representations of the new matter. For a spin-zero resonance with the quantum numbers of the vacuum, the ratios of resonant $WW$ and $ZZ$ to $\\gamma \\gamma$ channels, as well as the longitudinal versus transverse polarization fractions in the $WW$ and $ZZ$ channels, provide extraordinarily sensitive probes for possible mixing with the Higgs boson, while di-Higgs and di-top resonant channels, $hh$ and $tt$, provide somewhat less sensitivity. We present a survey of possible underlying models for di-gauge boson resonances by considering various limits for the mass of the new charged and strongly interac...

  17. Gamma-ray sources

    International Nuclear Information System (INIS)

    Results are presented from an analysis of the celestial gamma-ray fine-scale structure based on over half of the data which may ultimately be available from the COS-B satellite. A catalogue consisting of 25 gamma-ray sources measured at energies above 100 MeV is presented. (Auth.)

  18. Gamma-sterilization

    International Nuclear Information System (INIS)

    The author makes a survey of his experience in sterilization and sterility control of medical products. At present three different methods are used, steamsterilization, gassterilizing and gammasterilizing. The investments and costs for gamma radiation is presented and a comparison of the costs for gamma- and gassterilization including sterility control is made. (M.S.)

  19. Resolved photon and multi-component model for $\\gamma^*$p and $\\gamma^* \\gamma^*$ total cross section

    OpenAIRE

    Szczurek, A.; Pietrycki, T.

    2005-01-01

    We generalize our previous model for $\\gamma^* p$ scattering to $\\gamma \\gamma$ scattering. Performing a new simultaneous fit to $\\gamma^* p$ and $\\gamma \\gamma$ total cross section we find an optimal set of parameters to describe both processes. We propose new measures of factorization breaking for $\\gamma^* \\gamma^*$ collisions and present results for our new model.

  20. Colliding. gamma. e- and. gamma gamma. -beams on the basis of electron-positron linear colliders

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Tel' nov, V.I.

    1983-08-01

    Main properties of the ..gamma..e and ..gamma gamma.. collisions are discussed in some detail with application to the generation of colliding ..gamma..e and ..gamma gamma.. beams basing on the designed linear accelerators with colliding e/sup +/e/sup -/ beams, VLEEP and SLC, as it was proposed in a previous work. Intensive ..gamma.. beams with the energy 50 GeV would be produced from scattering of the laser light focused to the electron beams of the accelerators. Laser radiation is focused to the electron beam in the conversion region at a distance of about 10 cm from the place of collision. After scattering on electrons high-energy photons move practically along the electron primary trajectories and are focused in the collision region. The electrons are deflected from the collision region by means of approximately 1 T magnetic field. Then the produced ..gamma..-beam collides with an electron beam or a similar ..gamma..-beam. In the case when the maximum luminosity (L) is attained, the luminosity distribution in the invariant mass of the ..gamma..e or ..gamma gamma.. systems is wide. A monochromatization of the collisions up to the level of 5-10% is possible. That will entail a decrease in the luminosity, the procedure is most effective if one uses the electrons and the laser photons with opposite helicities. Examples of physically interesting problems to be investigated with the proposed ..gamma..e and ..gamma gamma.. beams are suggested.

  1. The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis.

    Science.gov (United States)

    He, Shu; Blombäck, Margareta; Bark, Niklas; Johnsson, Hans; Wallén, N Hakan

    2010-05-01

    The present study aimed to assess whether the fibrin network structure is modified by the direct thrombin-inhibitors lepirudin, argatroban or bivalirudin and by the indirect Xa-inhibitor danaparoid. Using an in vitro assay that imitates the physiological process of coagulation from thrombin generation to fibrin formation, we examined a normal plasma pool spiked with one of the inhibitors. At concentrations considered to be the plasma levels observed during therapy, almost no influence was detected for lepirudin despite clear-cut effects on "clotting time". However, argatroban, bivalirudin and danaparoid increased the fibrin gel permeability (Ks) to a similar extent. At concentrations higher than the "therapeutic" levels, the dose-response curve in the Ks assay became very steep for lepirudin while those were shallow for the others. In parallel with the drug-induced increases of Ks, larger network pores in 3D-microscopic images and significant shortenings in "clot lysis time" induced by addition of rtPA were observed. Recombinant factor VIII (rFVIII) added to danaparoid-treated samples profoundly counteracted the increase of Ks but had only a slight or no effect on the other drugs. Thus, in vitro, argatroban, bivalirudin and danaparoid have comparable anticoagulating effects, rendering the fibrin network more permeable and less resistant to fibrinolysis. For lepirudin, the steep dose-response curve supports previous clinical findings, i.e. this thrombin inhibitor has a narrow therapeutic window. Furthermore, our data suggest that the haemostatic agent, rFVIII, might be effective in treatment of bleeding complications induced by danaparoid. PMID:20216982

  2. Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial.

    Science.gov (United States)

    Barco, Stefano; Lankeit, Mareike; Binder, Harald; Schellong, Sebastian; Christ, Michael; Beyer-Westendorf, Jan; Duerschmied, Daniel; Bauersachs, Rupert; Empen, Klaus; Held, Matthias; Schwaiblmair, Martin; Fonseca, Cândida; Jiménez, David; Becattini, Cecilia; Quitzau, Kurt; Konstantinides, Stavros

    2016-07-01

    Pulmonary embolism (PE) is a potentially life-threatening acute cardiovascular syndrome. However, more than 95 % of patients are haemodynamically stable at presentation, and among them are patients at truly low risk who may qualify for immediate or early discharge. The Home Treatment of Pulmonary Embolism (HoT-PE) study is a prospective international multicentre single-arm phase 4 management (cohort) trial aiming to determine whether home treatment of acute low-risk PE with the oral factor Xa inhibitor rivaroxaban is feasible, effective, and safe. Patients with confirmed PE, who have no right ventricular dysfunction or free floating thrombi in the right atrium or ventricle, are eligible if they meet none of the exclusion criteria indicating haemodynamic instability, serious comorbidity or any condition mandating hospitalisation, or a familial/social environment unable to support home treatment. The first dose of rivaroxaban is given in hospital, and patients are discharged within 48 hours of presentation. Rivaroxaban is taken for at least three months. The primary outcome is symptomatic recurrent venous thromboembolism or PE-related death within three months of enrolment. Secondary outcomes include quality of life and patient satisfaction, and health care resource utilisation compared to existing data on standard-duration hospital treatment. HoT-PE is planned to analyse 1,050 enrolled patients, providing 80 % power to reject the null hypothesis that the recurrence rate of venous thromboembolism is >3 % with α≤0.05. If the hypothesis of HoT-PE is confirmed, early discharge and out-of-hospital treatment may become an attractive, potentially cost-saving option for a significant proportion of patients with acute PE.

  3. Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial.

    Science.gov (United States)

    Barco, Stefano; Lankeit, Mareike; Binder, Harald; Schellong, Sebastian; Christ, Michael; Beyer-Westendorf, Jan; Duerschmied, Daniel; Bauersachs, Rupert; Empen, Klaus; Held, Matthias; Schwaiblmair, Martin; Fonseca, Cândida; Jiménez, David; Becattini, Cecilia; Quitzau, Kurt; Konstantinides, Stavros

    2016-07-01

    Pulmonary embolism (PE) is a potentially life-threatening acute cardiovascular syndrome. However, more than 95 % of patients are haemodynamically stable at presentation, and among them are patients at truly low risk who may qualify for immediate or early discharge. The Home Treatment of Pulmonary Embolism (HoT-PE) study is a prospective international multicentre single-arm phase 4 management (cohort) trial aiming to determine whether home treatment of acute low-risk PE with the oral factor Xa inhibitor rivaroxaban is feasible, effective, and safe. Patients with confirmed PE, who have no right ventricular dysfunction or free floating thrombi in the right atrium or ventricle, are eligible if they meet none of the exclusion criteria indicating haemodynamic instability, serious comorbidity or any condition mandating hospitalisation, or a familial/social environment unable to support home treatment. The first dose of rivaroxaban is given in hospital, and patients are discharged within 48 hours of presentation. Rivaroxaban is taken for at least three months. The primary outcome is symptomatic recurrent venous thromboembolism or PE-related death within three months of enrolment. Secondary outcomes include quality of life and patient satisfaction, and health care resource utilisation compared to existing data on standard-duration hospital treatment. HoT-PE is planned to analyse 1,050 enrolled patients, providing 80 % power to reject the null hypothesis that the recurrence rate of venous thromboembolism is >3 % with α≤0.05. If the hypothesis of HoT-PE is confirmed, early discharge and out-of-hospital treatment may become an attractive, potentially cost-saving option for a significant proportion of patients with acute PE. PMID:27010343

  4. Holothurian glycosaminoglycan inhibits metastasis and thrombosis via targeting of nuclear factor-κB/tissue factor/Factor Xa pathway in melanoma B16F10 cells.

    Directory of Open Access Journals (Sweden)

    Yang Zhao

    Full Text Available Holothurian glycosaminoglycan (hGAG is a high-molecular-weight form of fucosylated chondroitin sulfate and has an antithrombotic effect. Our previous studies demonstrated that hGAG efficiently inhibited tumor cell metastasis. The interplays between thrombosis and tumor progression may have a major impact on hematogenous metastasis. In this study, we demonstrated that the mouse melanoma B16F10 cells treated with hGAG displayed a significant reduction of metastasis and coagulation capacity in vitro and in vivo. Mechanistic studies revealed that hGAG treatment in B16F10 cells remarkably inhibited the formation of fibrin through attenuating the generation of activated Factor Xa (FXa, without affecting the expression of urokinase (uPA and plasminogen activator inhibitor 1 (PAI-1 that involved in fibrinolysis. Moreover, hGAG treatment downregulated the transcription and protein expression of tissue factor (TF. Promoter deletions, site mutations and functional studies identified that the nuclear transcription factor NF-κB binding region is responsible for hGAG-induced inhibition of TF expression. While the hGAG treatment of B16F10 cells was unable to inhibit NF-κB expression and phosphorylation, hGAG significantly prevented nuclear translocation of NF-κB from the cytosol, a potential mechanism underlying the transcriptional suppression of TF. Moreover, hGAG markedly suppressed the activation of p38MAPK and ERK1/2 signaling pathways, the central regulators for the expression of metastasis-related matrix metalloproteinases (MMPs. Consequently, hGAG exerts a dual function in the inhibition of metastasis and coagulation activity in mouse melanoma B16F10 cells. Our studies suggest hGAG to be a promising therapeutic agent for metastatic cancer treatment.

  5. GammaWorkshops Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Ramebaeck, H. (ed.) (Swedish Defence Research Agency (Sweden)); Straalberg, E. (Institute for Energy Technology, Kjeller (Norway)); Klemola, S. (Radiation and Nuclear Safety Authority, STUK (Finland)); Nielsen, Sven P. (Technical Univ. of Denmark. Risoe National Lab. for Sustainable Energy, Roskilde (Denmark)); Palsson, S.E. (Icelandic Radiation Safety Authority (Iceland))

    2012-01-15

    Due to a sparse interaction during the last years between practioners in gamma ray spectrometry in the Nordic countries, a NKS activity was started in 2009. This GammaSem was focused on seminars relevant to gamma spectrometry. A follow up seminar was held in 2010. As an outcome of these activities it was suggested that the 2011 meeting should be focused on practical issues, e.g. different corrections needed in gamma spectrometric measurements. This three day's meeting, GammaWorkshops, was held in September at Risoe-DTU. Experts on different topics relevant for gamma spectrometric measurements were invited to the GammaWorkshops. The topics included efficiency transfer, true coincidence summing corrections, self-attenuation corrections, measurement of natural radionuclides (natural decay series), combined measurement uncertainty calculations, and detection limits. These topics covered both lectures and practical sessions. The practical sessions included demonstrations of tools for e.g. corrections and calculations of the above meantioned topics. (Author)

  6. Gamma-ray Astronomy

    CERN Document Server

    Hinton, Jim

    2007-01-01

    The relevance of gamma-ray astronomy to the search for the origin of the galactic and, to a lesser extent, the ultra-high-energy cosmic rays has long been recognised. The current renaissance in the TeV gamma-ray field has resulted in a wealth of new data on galactic and extragalactic particle accelerators, and almost all the new results in this field were presented at the recent International Cosmic Ray Conference (ICRC). Here I summarise the 175 papers submitted on the topic of gamma-ray astronomy to the 30th ICRC in Merida, Mexico in July 2007.

  7. The gamma function

    CERN Document Server

    Artin, Emil

    2015-01-01

    This brief monograph on the gamma function was designed by the author to fill what he perceived as a gap in the literature of mathematics, which often treated the gamma function in a manner he described as both sketchy and overly complicated. Author Emil Artin, one of the twentieth century's leading mathematicians, wrote in his Preface to this book, ""I feel that this monograph will help to show that the gamma function can be thought of as one of the elementary functions, and that all of its basic properties can be established using elementary methods of the calculus."" Generations of teachers

  8. Dynamic gamma knife radiosurgery

    Science.gov (United States)

    Luan, Shuang; Swanson, Nathan; Chen, Zhe; Ma, Lijun

    2009-03-01

    Gamma knife has been the treatment of choice for various brain tumors and functional disorders. Current gamma knife radiosurgery is planned in a 'ball-packing' approach and delivered in a 'step-and-shoot' manner, i.e. it aims to 'pack' the different sized spherical high-dose volumes (called 'shots') into a tumor volume. We have developed a dynamic scheme for gamma knife radiosurgery based on the concept of 'dose-painting' to take advantage of the new robotic patient positioning system on the latest Gamma Knife C™ and Perfexion™ units. In our scheme, the spherical high dose volume created by the gamma knife unit will be viewed as a 3D spherical 'paintbrush', and treatment planning reduces to finding the best route of this 'paintbrush' to 'paint' a 3D tumor volume. Under our dose-painting concept, gamma knife radiosurgery becomes dynamic, where the patient moves continuously under the robotic positioning system. We have implemented a fully automatic dynamic gamma knife radiosurgery treatment planning system, where the inverse planning problem is solved as a traveling salesman problem combined with constrained least-square optimizations. We have also carried out experimental studies of dynamic gamma knife radiosurgery and showed the following. (1) Dynamic gamma knife radiosurgery is ideally suited for fully automatic inverse planning, where high quality radiosurgery plans can be obtained in minutes of computation. (2) Dynamic radiosurgery plans are more conformal than step-and-shoot plans and can maintain a steep dose gradient (around 13% per mm) between the target tumor volume and the surrounding critical structures. (3) It is possible to prescribe multiple isodose lines with dynamic gamma knife radiosurgery, so that the treatment can cover the periphery of the target volume while escalating the dose for high tumor burden regions. (4) With dynamic gamma knife radiosurgery, one can obtain a family of plans representing a tradeoff between the delivery time and the

  9. Dynamic gamma knife radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Luan Shuang; Swanson, Nathan; Chen Zhe [Department of Computer Science, University of New Mexico, Albuquerque, NM 87131 (United States); Ma Lijun [Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143 (United States)], E-mail: sluan@cs.unm.edu, E-mail: nate@cs.unm.edu, E-mail: zchen@cs.unm.edu, E-mail: lijunma@radonc.ucsf.edu

    2009-03-21

    Gamma knife has been the treatment of choice for various brain tumors and functional disorders. Current gamma knife radiosurgery is planned in a 'ball-packing' approach and delivered in a 'step-and-shoot' manner, i.e. it aims to 'pack' the different sized spherical high-dose volumes (called 'shots') into a tumor volume. We have developed a dynamic scheme for gamma knife radiosurgery based on the concept of 'dose-painting' to take advantage of the new robotic patient positioning system on the latest Gamma Knife C(TM) and Perfexion(TM) units. In our scheme, the spherical high dose volume created by the gamma knife unit will be viewed as a 3D spherical 'paintbrush', and treatment planning reduces to finding the best route of this 'paintbrush' to 'paint' a 3D tumor volume. Under our dose-painting concept, gamma knife radiosurgery becomes dynamic, where the patient moves continuously under the robotic positioning system. We have implemented a fully automatic dynamic gamma knife radiosurgery treatment planning system, where the inverse planning problem is solved as a traveling salesman problem combined with constrained least-square optimizations. We have also carried out experimental studies of dynamic gamma knife radiosurgery and showed the following. (1) Dynamic gamma knife radiosurgery is ideally suited for fully automatic inverse planning, where high quality radiosurgery plans can be obtained in minutes of computation. (2) Dynamic radiosurgery plans are more conformal than step-and-shoot plans and can maintain a steep dose gradient (around 13% per mm) between the target tumor volume and the surrounding critical structures. (3) It is possible to prescribe multiple isodose lines with dynamic gamma knife radiosurgery, so that the treatment can cover the periphery of the target volume while escalating the dose for high tumor burden regions. (4) With dynamic gamma knife radiosurgery, one can

  10. Screening of gamma radiation-induced pathogen resistance rice lines against Xanthomonas oryzae pv. oryzae

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Chan Ju; Lee, Ha Yeon; Kim, Woong Bom; Ahmad, Raza; Moon, Jae Sun; Kwon, Suk Yoon [Korea Research Institute of Beoscience and Biotechnology, Daejeon (Korea, Republic of); Kim, Dong Sub [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2010-09-15

    Bacterial blight is one of the most serious diseases of rice (Oryza sativa L.), and it has been known that Xanthomonas oryzae pv. oryzae (Xoo) causes this disease symptom. To develop resistance rice cultivars against Xoo, 3,000 lines of M{sub 3}, which were irradiated with gamma ray, were tested by 'scissor-dip method' primarily, and 191 putative resistant lines were selected. In M{sub 4} generation, these lines were screened again with various ways such as measuring of symptom of bacterial blight in leaf, number of tiller, fresh weight, and phenotypic segregation ratio in next generation. Finally, six resistance lines were selected. RT-PCR analysis revealed that these lines displayed high level of R-genes such as Xa21, Pi36, and Pi-ta. These results indicate that mutations by gamma ray cause disruptions of regulatory signal transduction systems of these R-genes. Furthermore, these selected mutants could be useful for the development of rice cultivar resistant to Xoo.

  11. Monitoring low molecular weight heparins at therapeutic levels: dose-responses of, and correlations and differences between aPTT, anti-factor Xa and thrombin generation assays.

    Directory of Open Access Journals (Sweden)

    Owain Thomas

    Full Text Available Low molecular weight heparins (LMWH's are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa, activated partial thromboplastin time (aPTT and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.To examine the effects of two different LMWH's on the results of 4 different aPTT-tests, anti-FXa activity and thrombin generation and to assess the tests' concordance.Enoxaparin and tinzaparin were added ex-vivo in concentrations of 0.0, 0.5, 1.0 and 1.5 anti-FXa international units (IU/mL, to blood from 10 volunteers. aPTT was measured using two whole blood methods (Free oscillation rheometry (FOR and Hemochron Jr (HCJ and an optical plasma method using two different reagents (ActinFSL and PTT-Automat. Anti-FXa activity was quantified using a chromogenic assay. Thrombin generation (Endogenous Thrombin Potential, ETP was measured on a Ceveron Alpha instrument using the TGA RB and more tissue-factor rich TGA RC reagents.Methods' mean aPTT at 1.0 IU/mL LMWH varied between 54s (SD 11 and 69s (SD 14 for enoxaparin and between 101s (SD 21 and 140s (SD 28 for tinzaparin. ActinFSL gave significantly shorter aPTT results. aPTT and anti-FXa generally correlated well. ETP as measured with the TGA RC reagent but not the TGA RB reagent showed an inverse exponential relationship to the concentration of LMWH. The HCJ-aPTT results had the weakest correlation to anti-FXa and thrombin generation (Rs0.62-0.87, whereas the other aPTT methods had similar correlation coefficients (Rs0.80-0.92.aPTT displays a linear dose-response to LMWH. There is variation between aPTT assays. Tinzaparin increases aPTT and decreases thrombin generation more than enoxaparin at any given level of anti-FXa activity, casting doubt on anti-FXa's present gold standard status. Thrombin generation with tissue factor-rich activator is a promising method for monitoring LMWH's.

  12. Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment.

    Science.gov (United States)

    Graff, Jochen; Harder, Sebastian

    2013-04-01

    The direct factor Xa (FXa) inhibitors rivaroxaban, apixaban and edoxaban, and the thrombin inhibitor dabigatran etexilate (dabigatran) have gained approval for use in several indications, most notably for the prevention and treatment of venous thromboembolism (VTE) and for the prevention of stroke in patients with atrial fibrillation. Hepatic impairment can affect the disposition of these anticoagulants considerably not only because of the hepatic metabolism of the direct FXa inhibitors but also because moderate to severely impaired hepatic function will affect coagulation. This review describes the key pharmacological properties of novel oral anticoagulants with special attention to patients with impaired hepatic function. In subjects with moderately impaired liver function (i.e. Child-Pugh classification B), the area under the plasma concentration-time curve (AUC) of rivaroxaban (10 mg single dose) is increased by 2.27-fold, which is paralleled by an increase in FXa inhibition. The AUC of apixaban (5 mg single dose) is increased by 1.09-fold, whereas the AUC of edoxaban (15 mg single dose) is decreased by 4.8 % and the AUC of dabigatran (150 mg single dose) is decreased by 5.6 %. Specific labelling restrictions for rivaroxaban, apixaban and dabigatran regarding impaired hepatic function are based on both the Child-Pugh classification and liver-related exclusion criteria applied in pivotal clinical trials. Rivaroxaban is contraindicated in patients with hepatic disease associated with coagulopathy and clinically relevant bleeding risk, including cirrhotic patients classified as Child-Pugh B and C. Apixaban can be used with caution in patients with mild (Child-Pugh A) or moderate (Child-Pugh B) hepatic impairment or in patients with alanine aminotransferase and aspartate aminotransferase levels >2× upper limit of normal (ULN). Apixaban is not recommended in patients with severe hepatic impairment and is contraindicated in those with hepatic disease associated with

  13. Characterizations of {\\Gamma}-AG^{**}-groupoids by their {\\Gamma}-ideals

    CERN Document Server

    Khan, Madad

    2010-01-01

    In this paper we have discusses {\\Gamma}-left, {\\Gamma}-right, {\\Gamma}-bi-, {\\Gamma}-quasi-, {\\Gamma}-interior and {\\Gamma}-ideals in {\\Gamma}-AG^{**}-groupoids and regular {\\Gamma}-AG^{**}-groupoids. Moreover we have proved that the set of {\\Gamma}-ideals in a regular {\\Gamma}-AG^{**}-groupoid form a semilattice structure. Also we have characterized a regular {\\Gamma}-AG^{**}-groupoid in terms of left ideals.

  14. Characterizations of gamma-AG^{**}-groupoids by the properties their gamma-ideals

    CERN Document Server

    Khan, Madad; Rehman, Inayatur

    2010-01-01

    In this paper we have discusses {\\Gamma}-left, {\\Gamma}-right, {\\Gamma}-bi-, {\\Gamma}-quasi-, {\\Gamma}-interior and {\\Gamma}-ideals in {\\Gamma}-AG^{**}-groupoids and regular {\\Gamma}-AG^{**}-groupoids. Moreover we have proved that the set of {\\Gamma}-ideals in a regular {\\Gamma}-AG^{**}-groupoid form a semilattice structure. Also we have characterized a regular {\\Gamma}-AG^{**}-groupoid in terms of left ideals.

  15. Measurement of anomalous couplings ZZ gamma , Z gamma gamma and ZZZ

    CERN Document Server

    Matteuzzi, C

    2001-01-01

    The anomalous couplings Z gamma gamma , ZZ gamma and ZZZ have been studied at LEP 2 with the reactions e/sup +/e/sup -/ to qq gamma , e /sup +/e/sup -/ to nu nu gamma and e/sup +/e/sup to / ZZ at square root s from 189 to 202 GeV. Limits are derived on three gauge neutral bosons couplings combining the results of the 3 experiments L3, OPAL and DELPHI.

  16. Gamma ray camera

    Science.gov (United States)

    Perez-Mendez, Victor

    1997-01-01

    A gamma ray camera for detecting rays emanating from a radiation source such as an isotope. The gamma ray camera includes a sensor array formed of a visible light crystal for converting incident gamma rays to a plurality of corresponding visible light photons, and a photosensor array responsive to the visible light photons in order to form an electronic image of the radiation therefrom. The photosensor array is adapted to record an integrated amount of charge proportional to the incident gamma rays closest to it, and includes a transparent metallic layer, photodiode consisting of a p-i-n structure formed on one side of the transparent metallic layer, and comprising an upper p-type layer, an intermediate layer and a lower n-type layer. In the preferred mode, the scintillator crystal is composed essentially of a cesium iodide (CsI) crystal preferably doped with a predetermined amount impurity, and the p-type upper intermediate layers and said n-type layer are essentially composed of hydrogenated amorphous silicon (a-Si:H). The gamma ray camera further includes a collimator interposed between the radiation source and the sensor array, and a readout circuit formed on one side of the photosensor array.

  17. Close linkage of a blast resistance gene, Pias(t), with a bacterial leaf blight resistance gene, Xa1-as(t), in a rice cultivar ‘Asominori’

    Science.gov (United States)

    Endo, Takashi; Yamaguchi, Masayuki; Kaji, Ryota; Nakagomi, Koji; Kataoka, Tomomori; Yokogami, Narifumi; Nakamura, Toshiki; Ishikawa, Goro; Yonemaru, Jun-ichi; Nishio, Takeshi

    2012-01-01

    It has long been known that a bacterial leaf blight-resistant line in rice obtained from a crossing using ‘Asominori’ as a resistant parent also has resistance to blast, but a blast resistance gene in ‘Asominori’ has not been investigated in detail. In the present study, a blast resistance gene in ‘Asominori’, tentatively named Pias(t), was revealed to be located within 162-kb region between DNA markers YX4-3 and NX4-1 on chromosome 4 and to be linked with an ‘Asominori’ allele of the bacterial leaf blight resistance gene Xa1, tentatively named Xa1-as(t). An ‘Asominori’ allele of Pias(t) was found to be dominant and difference of disease severity between lines having the ‘Asominori’ allele of Pias(t) and those without it was 1.2 in disease index from 0 to 10. Pias(t) was also closely linked with the Ph gene controlling phenol reaction, suggesting the possibility of successful selection of blast resistance using the phenol reaction. Since blast-resistant commercial cultivars have been developed using ‘Asominori’ as a parent, Pias(t) is considered to be a useful gene in rice breeding for blast resistance. PMID:23341747

  18. Industrial 800xA系统在无缝钢管生产中的应用%Application of Industrial 800xA System in Seamless Tube Mill

    Institute of Scientific and Technical Information of China (English)

    李建军; 余志伟; 王歌; 刘占国

    2009-01-01

    Application of ABB Industrial 800xA System in Seamless Tube Mill is described,including technological process,system configuration,software function and performance analysis etc.The automation level,productivity and control accuracy in seamless tube are extremely improved by using Industrial 800xA system,stability and reliability of production are ensured as well.%介绍ABB Industrial 800xA系统在无缝钢管生产领域中的应用,主要包括工艺流程、系统配置、软件控制功能、性能分析等内容.该系统的使用显著地提高了缝钢管生产的自动化控制水平,有效地提升了生产节奏和控制精度,生产的稳定性和可靠性得到了有效保障.

  19. SVOM Gamma Ray Monitor

    CERN Document Server

    Dong, Yongwei; Li, Yanguo; Zhang, Yongjie; Zhang, Shuangnan

    2009-01-01

    The Space-based multi-band astronomical Variable Object Monitor (SVOM) mission is dedicated to the detection, localization and broad-band study of Gamma-Ray Bursts (GRBs) and other high-energy transient phenomena. The Gamma Ray Monitor (GRM) onboard is designed to observe the GRBs up to 5 MeV. With this instrument one of the key GRB parameter, Epeak, can be easily measured in the hard x-ray band. It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  20. SVOM gamma ray monitor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The space-based multi-band astronomical Variable Object Monitor(SVOM) mission is dedicated to the detection,localization and broad-band study of gamma-ray bursts(GRBs) and other high-energy transient phenomena.The gamma ray monitor(GRM) onboard is designed to observe GRBs up to 5 MeV.With this instrument,one of the key GRB parameters,Epeak,can be easily measured in the hard X-ray band.It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  1. Gamma Ray Bursts

    Science.gov (United States)

    Gehrels, Neil; Meszaros, Peter

    2012-01-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma-rays coming from the cosmos. They occur roughly once per day ,last typically lOs of seconds and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this review we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglows.

  2. Gamma-Ray Bursts

    Science.gov (United States)

    Gehrels, Neil; Mészáros, Péter

    2012-08-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma rays coming from the cosmos. They occur roughly once per day, typically last for tens of seconds, and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this Review, we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglow.

  3. Gamma Ray Bursts

    CERN Document Server

    Gehrels, Neil; 10.1126/science.1216793

    2012-01-01

    Gamma-ray bursts (GRBs) are bright flashes of gamma-rays coming from the cosmos. They occur roughly once per day, last typically 10s of seconds and are the most luminous events in the universe. More than three decades after their discovery, and after pioneering advances from space and ground experiments, they still remain mysterious. The launch of the Swift and Fermi satellites in 2004 and 2008 brought in a trove of qualitatively new data. In this review we survey the interplay between these recent observations and the theoretical models of the prompt GRB emission and the subsequent afterglows.

  4. Wsup(+-) boson production at the e/sup +/e/sup -/,. gamma. e and. gamma gamma. colliding beams

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Panfil, S.L.; Serbo, V.G.

    1983-11-21

    Wsup(+-) boson production in e/sup +/e/sup -/->W/sup +/W/sup -/, ..gamma..e->W/sup +/W/sup -/, ..gamma..e->W, ..gamma gamma..->W/sup +/W/sup -/ reactions at the e/sup +/e/sup -/, ..gamma..e and ..gamma gamma.. colliding beams is considered. What physical information can be extracted from such experiments, including those with polarized beams, is discussed. Conditions of observation, are considered together with the background problems.

  5. CKM angle $\\gamma$ from LHCb

    CERN Multimedia

    Smith, Jackson

    2015-01-01

    Results of the latest $\\gamma$ combination from LHCb are presented, along with the six LHCb measurements used as inputs. In addition, the anticipated precision attainable for measuring $\\gamma$ after the LHCb Upgrade is outlined

  6. Interferon Gamma-1b Injection

    Science.gov (United States)

    Interferon gamma-1b injection is used to reduce the frequency and severity of serious infections in people ... with severe, malignant osteopetrosis (an inherited bone disease). Interferon gamma-1b is in a class of medications ...

  7. Proprioceptive evoked gamma oscillations

    DEFF Research Database (Denmark)

    Arnfred, S.M.; Hansen, Lars Kai; Parnas, J.;

    2007-01-01

    A proprioceptive stimulus consisting of a weight change of a handheld load has recently been shown to elicit an evoked potential. Previously, somatosensory gamma oscillations have only been evoked by electrical stimuli. We conjectured that a natural proprioceptive stimulus also would be able...

  8. The shifting gamma perception

    NARCIS (Netherlands)

    Besuijen, J.

    2005-01-01

    True to life, color display and color management depend on a proper technical model of the display used. Current gamma models and fitting procedures are not accurate in modeling the lower part of the tone reproduction curve. The GOG- and GOGO-model used in color management standards tend to clip the

  9. Proprioceptive evoked gamma oscillations

    DEFF Research Database (Denmark)

    Arnfred, Sidse M; Hansen, Lars Kai; Parnas, Josef;

    2007-01-01

    A proprioceptive stimulus consisting of a weight change of a handheld load has recently been shown to elicit an evoked potential. Previously, somatosensory gamma oscillations have only been evoked by electrical stimuli. We conjectured that a natural proprioceptive stimulus also would be able to...

  10. Industrial radiography. Gamma radiography

    International Nuclear Information System (INIS)

    Informations are given on gamma radiodefectology regulations, entire references and main dispositions applicable to each state of the European Economic Community. The content includes previous arrangements for source acquisition, holding and use of the sources, transport, accidents, civil liability of the source holder, person insurance against radiation hazards and contamination, property insurance, penal liability of the source holder

  11. Chemist's gamma-ray table

    International Nuclear Information System (INIS)

    An edited listing of gamma-ray information has been prepared. Prominent gamma rays originating from nuclides with half lives long enough to be seen in radiochemical experiments are included. Information is ordered by nuclide in one section and by energy in a second section. This shorter listing facilitates identification of nuclides responsible for gamma rays observed in experiments

  12. Measurement of {\\eta} meson production in {\\gamma}{\\gamma} interactions and {\\Gamma}({\\eta}-->{\\gamma}{\\gamma}) with the KLOE detector

    CERN Document Server

    :,; Badoni, D; Balwierz-Pytko, I; Bencivenni, G; Bini, C; Bloise, C; Bossi, F; Branchini, P; Budano, A; Balkestaahl, L Caldeira; Capon, G; Ceradini, F; Ciambrone, P; Czerwinski, E; Dane, E; De Lucia, E; De Robertis, G; De Santis, A; Di Domenico, A; Di Donato, C; Di Salvo, R; Domenici, D; Erriquez, O; Fanizzi, G; Fantini, A; Felici, G; Fiore, S; Franzini, P; Gauzzi, P; Giardina, G; Giovannella, S; Gonnella, F; Graziani, E; Happacher, F; Heijkenskj, L; Hoistad, B; Iafolla, L; Jacewicz, M; Johansson, T; Kupsc, A; Lee-Franzini, J; Leverington, B; Loddo, F; Loffredo, S; Mandaglio, G; Martemianov, M; Martini, M; Mascolo, M; Messi, R; Miscetti, S; Morello, G; Moricciani, D; Moskal, P; Nguyen, F; Passeri, A; Patera, V; Longhi, I Prado; Ranieri, A; Redmer, C F; Santangelo, P; Sarra, I; Schioppa, M; Sciascia, B; Silarski, M; Taccini, C; Tortora, L; Venanzoni, G; Wislicki, W; Wolke, M; Zdebik, J

    2012-01-01

    We present a measurement of {\\eta} meson production in photon-photon interactions produced by electron-positron beams colliding with \\sqrt{s}=1 GeV. The measurement is done with the KLOE detector at the \\phi-factory DA{\\Phi}NE with an integrated luminosity of 0.24 fb^{-1}. The e^+e^- --> e^+e^-{\\eta} cross section is measured without detecting the outgoing electron and positron, selecting the decays {\\eta}-->{\\pi}^+{\\pi}^-{\\pi}^0 and {\\eta}-->{\\pi}^0{\\pi}^0{\\pi}^0. The most relevant background is due to e^+e^- --> {\\eta}{\\gamma} when the monochromatic photon escapes detection. The cross section for this process is measured as {\\sigma}(e^+e^- -->{\\eta}{\\gamma}) = (856 \\pm 8_{stat} \\pm 16_{syst}) pb. The combined result for the e^+e^- -->e^+e^-{\\eta} cross section is {\\sigma}(e^+e^- -->e^+e^-{\\eta}) = (32.72 \\pm 1.27_{stat} \\pm 0.70_{syst}) pb. From this we derive the partial width {\\Gamma}({\\eta}-->{\\gamma}{\\gamma}) = (520 \\pm 20_{stat} \\pm 13_{syst}) eV. This is in agreement with the world average and is the ...

  13. Gamma-ray performance of the GAMMA-400 detector

    CERN Document Server

    Cumani, P; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Sarkar, R; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    GAMMA-400 is a new space mission, designed as a dual experiment, capable to study both high energy gamma rays (from $\\sim$100 MeV to few TeV) and cosmic rays (electrons up to 20 TeV and nuclei up to $\\sim$10$^{15}$ eV). The full simulation framework of GAMMA-400 is based on the Geant4 toolkit. The details of the gamma-ray reconstruction pipeline in the three main instruments (Tracker, Imaging Calorimeter, Homogeneous Calorimeter) will be outlined. The performance of GAMMA-400 (PSF, effective area and sensitivity) have been obtained using this framework. The most updated results on them will be shown.

  14. The finite mass calculations for Gamma Gamma --> L+ L- Gamma process

    OpenAIRE

    Makarenko, V. V.; T.V. Shishkina

    2003-01-01

    The process $\\gamma\\gamma\\to l^+ l^- \\gamma$ will be used for the photon beams luminosity measurement when the total angular momentum of colliding photons equals zero. The previous studies of this process were performed in the chiral limit. But the mass contribution should be taken into account.

  15. BUCS: Patterns and Robustness: Experimentation with Safety Patterns in Safety-Critical Software Systems

    OpenAIRE

    Ljosland, Ingvar

    2006-01-01

    In modern society, we rely on safely working software systems. This is the final report in a masters degree project to reveal key issues in the science field of computer software architecture and design of safety-critical software systems. A pre-study of a navigation system implied that functionality related problems and safety-critical problems do not stack one to one, but rather is a case of solving these aspects in different layers. This means that changes in software systems functionalit...

  16. Precise measurement of {gamma}(K{yields}e {nu}({gamma}))/{gamma}(K{yields}{mu} {nu}({gamma})) and study of K{yields}e {nu} {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosino, F.; Massarotti, P.; Meola, S.; Napolitano, M. [Dipartimento di Scienze Fisiche dell' Universita ' ' Federico II' ' , Napoli (Italy); INFN Sezione di Napoli, Napoli (Italy); Antonelli, A.; Antonelli, M.; Bencivenni, G.; Bloise, C.; Bossi, F.; Capon, G.; Capussela, T.; Ciambrone, P.; De Lucia, E.; De Simone, P.; Dreucci, M.; Felici, G.; Gatti, C.; Giovannella, S.; Jacewicz, M.; Lanfranchi, G.; Miscetti, S.; Moulson, M.; Murtas, F.; Palutan, M.; Santangelo, P.; Sciascia, B.; Sibidanov, A.; Spadaro, T.; Venanzoni, G. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Archilli, F. [Dipartimento di Fisica dell' Universita ' ' Tor Vergata' ' , Rome (Italy); INFN Sezione di Roma Tor Vergata, Rome (Italy); Beltrame, P.; Denig, A.; Mueller, S. [Johannes Gutenberg-Universitaet, Institut fuer Kernphysik, Mainz (Germany); Bini, C.; De Santis, A.; De Zorzi, G.; Di Domenico, A.; Fiore, S.; Franzini, P.; Gauzzi, P. [Dipartimento di Fisica dell' Universita ' ' La Sapienza' ' , Rome (Italy); INFN Sezione di Roma, Rome (Italy); Bocchetta, S.; Ceradini, F.; Di Micco, B.; Nguyen, F. [Dipartimento di Fisica dell' Universita ' ' Roma Tre' ' , Rome (Italy); INFN Sezione di Roma Tre, Rome (Italy); Branchini, P.; Graziani, E.; Passeri, A.; Tortora, L. [INFN Sezione di Roma Tre, Rome (Italy); Capriotti, D. [Dipartimento di Fisica dell' Universita ' ' Roma Tre' ' , Rome (Italy); Di Donato, C. [INFN Sezione di Napoli, Napoli (Italy); Kulikov, V. [Institute for Theoretical and Experimental Physics, Moscow (Russian Federation); Lee-Franzini, J. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); State University of New York, Physics Department, Stony Brook (United States); Martini, M.; Patera, V.; Versaci, R. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Dipartimento di Energetica dell' Universita ' ' La Sapienza' ' , Rome (Italy); Valente, P. [INFN Sezione di Roma, Rome (Italy)

    2009-12-15

    We present a precise measurement of the ratio R{sub K}={gamma}(K{yields}e{nu}({gamma}))/{gamma}(K{yields}{mu}{nu}({gamma})) and a study of the radiative process K{yields}e{nu}{gamma}, performed with the KLOE detector. The results are based on data collected at the Frascati e{sup +}e{sup -} collider DA {phi}NE for an integrated luminosity of 2.2 fb{sup -1}. We find R{sub K}=(2.493{+-}0.025{sub stat}{+-}0.019{sub syst}) x 10{sup -5}, in agreement with the Standard Model expectation. This result is used to improve constraints on parameters of the Minimal Supersymmetric Standard Model with lepton flavor violation. We also measured the differential decay rate d {gamma}(K{yields}e{nu}{gamma})/dE{sub {gamma}} for photon energies 10gamma}}<250 MeV. Results are compared with predictions from theory. (orig.)

  17. Novel gamma cameras

    International Nuclear Information System (INIS)

    The gamma-ray cameras described are based on radiation imaging devices which permit the direct recording of the distribution of radioactive material from a radiative source, such as a human organ. They consist in principle of a collimator, a converter matrix converting gamma photons to electrons, and an electron image multiplier producing a multiplied electron output, and means for reading out the information. The electron image multiplier is a device which produces a multiplied electron image. It can be in principle, either gas avalanche electron multiplier or a multi-channel plate. The multi-channel plate employed is a novel device, described elsewhere. The three described embodiments, in which the converter matrix can be either of metal type or of scintillation crystal type, were designed and are being developed

  18. Gamma rays in thunderstorms

    International Nuclear Information System (INIS)

    Not only lightning occur in thunderstorms but also luminous flashes that are emitted upwards over the clouds. These flashes have been studied for 20 years. Satellites have detected gamma flashes with an energy of 30 MeV. It was thought that these flashes resulted from collisions between cosmic particles and cloud molecules but recent results from the Italian Agile satellite question this explanation. Gamma flashes with an energy of 100 MeV have been detected which is too high an energy to be explained by collisions with cosmic particles. Another result show the existence of very strong acceleration of electrons in areas where some type of flashes are likely to happen. (A.C.)

  19. Gamma camera system

    International Nuclear Information System (INIS)

    A detailed description is given of a novel gamma camera which is designed to produce superior images than conventional cameras used in nuclear medicine. The detector consists of a solid state detector (e.g. germanium) which is formed to have a plurality of discrete components to enable 2-dimensional position identification. Details of the electronic processing circuits are given and the problems and limitations introduced by noise are discussed in full. (U.K.)

  20. Gamma-Ray Localization of Terrestrial Gamma-Ray Flashes

    CERN Document Server

    Marisaldi, M; Trois, A; Giuliani, A; Tavani, M; Labanti, C; Fuschino, F; Bulgarelli, A; Longo, F; Barbiellini, G; Del Monte, E; Moretti, E; Trifoglio, M; Costa, E; Caraveo, P; Cattaneo, P W; Chen, A; D'Ammando, F; De Paris, G; Di Cocco, G; Di Persio, G; Donnarumma, I; Evangelista, Y; Feroci, M; Ferrari, A; Fiorini, M; Froysland, T; Galli, M; Gianotti, F; Lapshov, I; Lazzarotto, F; Lipari, P; Mereghetti, S; Morselli, A; Pacciani, L; Pellizzoni, A; Perotti, F; Picozza, P; Piano, G; Pilia, M; Prest, M; Pucella, G; Rapisarda, M; Rappoldi, A; Rubini, A; Sabatini, S; Soffitta, P; Striani, E; Vallazza, E; Vercellone, S; Vittorini, V; Zambra, A; Zanello, D; Antonelli, L A; Colafrancesco, S; Cutini, S; Giommi, P; Lucarelli, F; Pittori, C; Santolamazza, P; Verrecchia, F; Salotti, L; 10.1103/PhysRevLett.105.128501

    2010-01-01

    Terrestrial Gamma-Ray Flashes (TGFs) are very short bursts of high energy photons and electrons originating in Earth's atmosphere. We present here a localization study of TGFs carried out at gamma-ray energies above 20 MeV based on an innovative event selection method. We use the AGILE satellite Silicon Tracker data that for the first time have been correlated with TGFs detected by the AGILE Mini-Calorimeter. We detect 8 TGFs with gamma-ray photons of energies above 20 MeV localized by the AGILE gamma-ray imager with an accuracy of 5-10 degrees at 50 MeV. Remarkably, all TGF-associated gamma rays are compatible with a terrestrial production site closer to the sub-satellite point than 400 km. Considering that our gamma rays reach the AGILE satellite at 540 km altitude with limited scattering or attenuation, our measurements provide the first precise direct localization of TGFs from space.

  1. Gamma heating in LMFBR media

    International Nuclear Information System (INIS)

    State-of-the-art approaches for the calculation of gamma heating in LMFBR core, blanket and reflector regions have been evaluated, with particular emphasis on coupled neutron-gamma methods/cross section sets. The major source of calculational error was found to be the apparent failure to impose a mass-energy balance on total gamma energy yield from neutron capture and other interactions in the preparation of representative neutron-gamma cross section sets. The applicability of many simplifying assumptions was demonstrated, including: volume-weighted homogenization, insensitivity to the shape of the gamma-source-spectrum, gamma energy deposition equal to gamma energy source more than 10 cm inside large zones of uniform composition, and the negligible effect of bremsstrahlung. A simple one-group method was developed to permit rapid, accurate estimation of the large (factor of 2) changes in the gamma energy deposition-to-source ratio possible near region interfaces. The approach, which also ensures conservation of mass-energy, was used in conjunction with coupled neutron-gamma computations to verify that previous experimental measurements of gamma heating in an LMFBR blanket mockup at M. I. T. were in accord with theoretical expectations within the experimental precision of +-10%

  2. Gamma heating in LMFBR media

    Energy Technology Data Exchange (ETDEWEB)

    Kalra, M.S.; Drisoll, M.J.

    1976-02-01

    State-of-the-art approaches for the calculation of gamma heating in LMFBR core, blanket and reflector regions have been evaluated, with particular emphasis on coupled neutron-gamma methods/cross section sets. The major source of calculational error was found to be the apparent failure to impose a mass-energy balance on total gamma energy yield from neutron capture and other interactions in the preparation of representative neutron-gamma cross section sets. The applicability of many simplifying assumptions was demonstrated, including: volume-weighted homogenization, insensitivity to the shape of the gamma-source-spectrum, gamma energy deposition equal to gamma energy source more than 10 cm inside large zones of uniform composition, and the negligible effect of bremsstrahlung. A simple one-group method was developed to permit rapid, accurate estimation of the large (factor of 2) changes in the gamma energy deposition-to-source ratio possible near region interfaces. The approach, which also ensures conservation of mass-energy, was used in conjunction with coupled neutron-gamma computations to verify that previous experimental measurements of gamma heating in an LMFBR blanket mockup at M. I. T. were in accord with theoretical expectations within the experimental precision of +-10%.

  3. The GAMMA-400 Space Mission

    CERN Document Server

    Cumani, P; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    GAMMA-400 is a new space mission which will be installed on board the Russian space platform Navigator. It is scheduled to be launched at the beginning of the next decade. GAMMA-400 is designed to study simultaneously gamma rays (up to 3 TeV) and cosmic rays (electrons and positrons from 1 GeV to 20 TeV, nuclei up to 10$^{15}$-10$^{16}$ eV). Being a dual-purpose mission, GAMMA-400 will be able to address some of the most impelling science topics, such as search for signatures of dark matter, cosmic-rays origin and propagation, and the nature of transients. GAMMA-400 will try to solve the unanswered questions on these topics by high-precision measurements of the Galactic and extragalactic gamma-ray sources, Galactic and extragalactic diffuse emission and the spectra of cosmic-ray electrons + positrons and nuclei, thanks to excellent energy and angular resolutions.

  4. Gamma Oscillations and Visual Binding

    Science.gov (United States)

    Robinson, Peter A.; Kim, Jong Won

    2006-03-01

    At the root of visual perception is the mechanism the brain uses to analyze features in a scene and bind related ones together. Experiments show this process is linked to oscillations of brain activity in the 30-100 Hz gamma band. Oscillations at different sites have correlation functions (CFs) that often peak at zero lag, implying simultaneous firing, even when conduction delays are large. CFs are strongest between cells stimulated by related features. Gamma oscillations are studied here by modeling mm-scale patchy interconnections in the visual cortex. Resulting predictions for gamma responses to stimuli account for numerous experimental findings, including why oscillations and zero-lag synchrony are associated, observed connections with feature preferences, the shape of the zero-lag peak, and variations of CFs with attention. Gamma waves are found to obey the Schroedinger equation, opening the possibility of cortical analogs of quantum phenomena. Gamma instabilities are tied to observations of gamma activity linked to seizures and hallucinations.

  5. gamma. -hexachlorocyclohexane (. gamma. -HCH) activates washed rabbit platelets

    Energy Technology Data Exchange (ETDEWEB)

    Lalau-Keraly, C.; Delautier, D.; Benveniste, J.; Puiseux-Dao, S.

    1986-03-01

    In guinea-pig macrophages, ..gamma..-HCH triggers activation of the phosphatidylinositol cycle and Ca/sup 2 +/ mobilization. Since these two biochemical events are also involved in platelet activation, the authors examined the effects of ..gamma..-HCH on washed rabbit platelets. Release of /sup 14/C-serotonin (/sup 14/C-5HT) and ATP from platelets prelabelled with /sup 14/C-5HT was measured simultaneously with aggregation. ..gamma..-HCH induced shape-change, aggregation and release reaction of platelets. Maximal aggregation (89 arbitrary units, AU), was observed using 170 ..mu..M ..gamma..-HCH, and was associated with 38.1 +/- 6.9% and 161 +/- 48 nM for /sup 14/C-5HT and ATP release respectively (mean +/- 1 SD, n=3). Using 80 ..mu..M ..gamma..-HCH yielded 18 AU, 12.8 +/- 1.0% and 27 +/- 14 nM for aggregation, C-5HT and ATP release respectively (n=3). No effect was observed with 40 ..mu.. M ..gamma..-HCH. Aspirin (ASA), a cyclooxygenase blocker, did not affect ..gamma..-HCH-induced platelet activation. Apyrase (APY), an ADP scavenger, inhibited by 90% aggregation induced by 170 ..mu..M ..gamma..-HCH and slightly inhibited (15%) the /sup 14/C-5HT release. In the presence of both ASA and APY, 96% inhibition of aggregation and 48% inhibition of /sup 14/C-5HT release were observed. Thus, ..gamma..-HCH induced platelet activation in a dose-dependent manner ADP, but not cyclooxygenase-dependent arachidonate metabolites, is involved in ..gamma..-HCH-induced aggregation, whereas, both appear to play a role in ..gamma..-HCH-induced release reaction.

  6. Simultaneous beta and gamma spectroscopy

    Science.gov (United States)

    Farsoni, Abdollah T.; Hamby, David M.

    2010-03-23

    A phoswich radiation detector for simultaneous spectroscopy of beta rays and gamma rays includes three scintillators with different decay time characteristics. Two of the three scintillators are used for beta detection and the third scintillator is used for gamma detection. A pulse induced by an interaction of radiation with the detector is digitally analyzed to classify the type of event as beta, gamma, or unknown. A pulse is classified as a beta event if the pulse originated from just the first scintillator alone or from just the first and the second scintillator. A pulse from just the third scintillator is recorded as gamma event. Other pulses are rejected as unknown events.

  7. Applied gamma-ray spectrometry

    CERN Document Server

    Dams, R; Crouthamel, Carl E

    1970-01-01

    Applied Gamma-Ray Spectrometry covers real life application of the gamma-ray and the devices used in their experimental studies. This book is organized into 9 chapters, and starts with discussions of the various decay processes, the possible interaction mechanisms of gamma radiation with matter, and the intrinsic and extrinsic variables, which affect the observed gamma-ray and X-ray spectra. The subsequent chapters deal with the properties and fabrication of scintillation detectors, semiconductor detectors, and proportional gas counters. These chapters present some of the most widely utilized

  8. Determination of the $e^+ e^- \\to \\gamma \\gamma (\\gamma)$ cross-section at LEP 2

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alderweireld, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Ballestrero, A; Bambade, P; Barbier, R; Bardin, Dimitri Yuri; Barker, G J; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Bugge, L; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F R; Chapkin, M M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L S; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Dris, M; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J A; Gandelman, M; García, C; Gavillet, P; Gazis, E N; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Hultqvist, K; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E C; Kernel, G; Kersevan, B P; Kerzel, U; Kiiskinen, A P; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Nassiakou, M; Navarria, Francesco Luigi; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, R; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V F; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, Antonio; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Segar, A; Sekulin, R L; Siebel, M; Sissakian, A N; Smadja, G; Smirnova, O G; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I; Vegni, G; Veloso, F; Venus, W A; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O P; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zintchenko, A; Zupan, M

    2004-01-01

    A test of the benchmark QED process e+e- -> gamma gamma (gamma) is reported, using the data collected with the DELPHI detector at LEP 2. The data analysed were recorded at centre-of-mass energies ranging from 161 GeV to 208 GeV and correspond to a total integrated luminosity of 656.4 pb^{-1}. The Born cross-section for the process e+e- -> gamma gamma (gamma) was determined, confirming the validity of QED at the highest energies ever attained in electron-positron collisions. Lower limits on the parameters of a number of possible deviations from QED, predicted within theoretical frameworks expressing physics beyond the Standard Model, were derived.

  9. Decays $h\\to \\gamma \\gamma, \\, \\gamma Z$ in the Two Higgs Doublet Model Type III

    CERN Document Server

    Cordero-Cid, A; Honorato, C G; Moretti, S

    2015-01-01

    We study the enhancement of the branching ratios of the decays $h \\to \\gamma \\gamma, \\, \\gamma Z$ in the Two Higgs Doublet Model Type III, assuming a four-zero Yukawa Texture and a general Higgs potential. We show that these processes are very sensitive to the flavor pattern of the Yukawa texture and the structure of the triple coupling $h H^\\pm H^\\mp$ from the Higgs potential. We can accomodate the parameters of the model such that one can obtain the $h \\to\\gamma \\gamma$ rates reported by the LHC and at the same time we can get a $ h \\to \\gamma Z$ fraction larger than in the SM and within experimental reach. The possibility of obtaining a light charged Higgs boson within the ensuing parameter space and compatible with current experimental measurements is also presented.

  10. Advantages of exclusive \\gamma\\gamma production to probe high mass systems

    CERN Document Server

    Martin, A D

    2016-01-01

    We recall that the exclusive production of high mass objects via \\gamma\\gamma fusion at the LHC is not strongly suppressed in comparison with inclusive \\gamma\\gamma fusion. Therefore it may be promising to study new objects produced by the \\gamma\\gamma subprocess in experiments with exclusive kinematics. We list the main advantages of exclusive experiments.

  11. The GAMMA-400 Space Experiment: Gammas, Electrons and Nuclei Measurements

    Science.gov (United States)

    Mocchiutti, E.; Galper, A. M.; Adriani, O.; Aptekar, R. L.; Arkhangelskaja, I. V.; Arkhangelskiy, A. I.; Boezio, M.; Bonvicini, V.; Boyarchuk, K. A.; Carbone, R.; Cumani, P.; Fradkin, M. I.; Gusakov, Yu. V.; Kaplin, V. A.; Kachanov, V. A.; Kheymits, M. D.; Leonov, A. A.; Longo, F.; Mazets, E. P.; Maestro, P.; Marrocchesi, P.; Mereminskiy, I. A.; Mikhailov, V. V.; Moiseev, A. A.; Mori, N.; Moskalenko, I. V.; Naumov, P. Yu.; Papini, P.; Picozza, P.; Rodin, V. G.; Runtso, M. F.; Sarkar, R.; Sparvoli, R.; Spillantini, P.; Suchkov, S. I.; Tavani, M.; Topchiev, N. P.; Vacchi, A.; Vannuccini, E.; Yurkin, Yu. T.; Zampa, N.; Zverev, V. G.; Zirakashvili, V. N.

    2013-06-01

    The present design of the new space gamma-ray telescope GAMMA-400 for the energy range 50 MeV-3 TeV is presented. The proposed instrument has an angular resolution of 1-2 degrees at E(γ)˜100 MeV and ˜0.01 degrees at E(γ)>100 GeV and an energy resolution ˜1% at E(γ)>100 GeV. By means of a deep segmented calorimeter high energy electron flux can be studied, with a proton rejection factor of about 106. The GAMMA-400 experiment is optimized to address a broad range of science topics, such as search for signatures of dark matter, studies of galactic and extragalactic gamma-ray sources, galactic and extragalactic diffuse emission, gamma-ray bursts, as well as high-precision measurements of spectra of high energy electrons, protons and nuclei up to the knee.

  12. Generalized gamma frailty model.

    Science.gov (United States)

    Balakrishnan, N; Peng, Yingwei

    2006-08-30

    In this article, we present a frailty model using the generalized gamma distribution as the frailty distribution. It is a power generalization of the popular gamma frailty model. It also includes other frailty models such as the lognormal and Weibull frailty models as special cases. The flexibility of this frailty distribution makes it possible to detect a complex frailty distribution structure which may otherwise be missed. Due to the intractable integrals in the likelihood function and its derivatives, we propose to approximate the integrals either by Monte Carlo simulation or by a quadrature method and then determine the maximum likelihood estimates of the parameters in the model. We explore the properties of the proposed frailty model and the computation method through a simulation study. The study shows that the proposed model can potentially reduce errors in the estimation, and that it provides a viable alternative for correlated data. The merits of proposed model are demonstrated in analysing the effects of sublingual nitroglycerin and oral isosorbide dinitrate on angina pectoris of coronary heart disease patients based on the data set in Danahy et al. (sustained hemodynamic and antianginal effect of high dose oral isosorbide dinitrate. Circulation 1977; 55:381-387). PMID:16220516

  13. Diffuse gamma radiation

    Science.gov (United States)

    Fichtel, C. E.; Simpson, G. A.; Thompson, D. J.

    1977-01-01

    An examination of the intensity, energy spectrum, and spatial distribution of the diffuse gamma-radiation observed by SAS-2 satellite away from the galactic plane in the energy range above 35 MeV has shown that it consists of two components. One component is generally correlated with galactic latitudes, the atomic hydrogen column density was deduced from 21 cm measurements, and the continuum radio emission, believed to be synchrotron emission. It has an energy spectrum similar to that in the plane and joins smoothly to the intense radiation from the plane. It is therefore presumed to be of galactic origin. The other component is apparently isotropic, at least on a coarse scale, and has a steep energy spectrum. No evidence is found for a cosmic ray halo surrounding the galaxy in the shape of a sphere or oblate spheroid with galactic dimensions. Constraints for a halo model with significantly larger dimensions are set on the basis of an upper limit to the gamma-ray anisotropy.

  14. The neutron-gamma Feynman variance to mean approach: gamma detection and total neutron-gamma detection (theory and practice)

    OpenAIRE

    Chernikova, Dina; Axell, Kåre; Avdic, Senada; Pázsit, Imre; Nordlund, Anders

    2014-01-01

    Two versions of the neutron-gamma variance to mean (Feynman-alpha method or Feynman-Y function) formula for either gamma detection only or total neutron-gamma detection, respectively, are derived and compared in this paper. The new formulas have a particular importance for detectors of either gamma photons or detectors sensitive to both neutron and gamma radiation. If applied to a plastic or liquid scintillation detector, the total neutron-gamma detection Feynman-Y expression corresponds to a...

  15. Gamma-Gamma Absorption in the Broad Line Region Radiation Fields of Gamma-Ray Blazars

    CERN Document Server

    Boettcher, Markus

    2016-01-01

    The expected level of gamma-gamma absorption in the Broad Line Region (BLR) radiation field of gamma-ray loud Flat Spectrum Radio Quasars (FSRQs)is evaluated as a function of the location of the gamma-ray emission region. This is done self-consistently with parameters inferred from the shape of the spectral energy distribution (SED) in a single-zone leptonic EC-BLR model scenario. We take into account all geometrical effects both in the calculation of the gamma-gamma opacity and the normalization of the BLR radiation energy density. As specific examples, we study the FSRQs 3C279 and PKS 1510-089, keeping the BLR radiation energy density at the location of the emission region fixed at the values inferred from the SED. We confirm previous findings that the optical depth due to $\\gamma\\gamma$ absorption in the BLR radiation field exceeds unity for both 3C279 and PKS 1510-089 for locations of the gamma-ray emission region inside the inner boundary of the BLR. It decreases monotonically, with distance from the cen...

  16. Colliding. gamma. e and. gamma gamma. beams from single-pass e/sup +/e/sup -/ accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Tel' nov, V.I.

    1983-08-01

    A detailed discussion is given of the main characteristics of ..gamma..e and ..gamma gamma.. collisions in the scheme previously proposed by the authors for obtaining colliding ..gamma..e and ..gamma gamma.. beams on the basis of the planned linear accelerators with e/sup +/e/sup -/ colliding beams VLEPP and SLC. It is proposed to obtain intense ..gamma.. beams with energy ..omega..approx.E/sub e/> or =50 GeV by scattering of laser light focused onto the electron beams of these accelerators. In the case when the maximum luminosity is achieved, L/sub gammae/approx.L/sub e/e or L/sub gammagamma/approx.L/sub e/e, the distribution of the luminosity in the invariant mass of the ..gamma..e or ..gamma gamma.. system is broad. Monochromatization of the collisions to a level 5--10% is possible. It involves a decrease of luminosity and is most efficient for use of electrons and laser photons with helicities of opposite sign. Examples of interesting physics problems for the proposed ..gamma..e and ..gamma gamma.. beams are given.

  17. Gamma-hadron families and scaling violation

    Science.gov (United States)

    Gaisser, T. K.; Stanev, T.; Wrotniak, J. A.

    1985-01-01

    For three different interaction models we have simulated gamma-hadron families, including the detector (Pamir emulsion chamber) response. Rates of gamma families, hadrons, and hadron-gamma ratios were compared with experiments.

  18. Cyclic oxidation behavior of beta+gamma overlay coatings on gamma and gamma+gamma-prime alloys

    Science.gov (United States)

    Nesbitt, J. A.; Pilsner, B. H.; Carol, L. A.; Heckel, R. W.

    1984-01-01

    Detailed experimental studies of the cyclic oxidation behavior of low-pressure plasma sprayed beta+gamma coasting on gamma-phase Ni-Cr-Al alloys have shown the correlation of weight change, oxide type, and Cr and Al concentration-distance profiles as a function of oxidation time. Of special interest was the transition to breakway oxidation due to the loss of the Al flux to the oxide and the failure of the coated alloy to form an Al2O3-rich oxide scale. The experimental results on beta+gamma/gamma coating systems were used as the basis of a numerical model (ternary, semi-infinite, finite-difference analysis) which accurately predicted changes in Cr and Al concentration-distance profiles. The model was used to study parameters critical to enhancing the life of coatings which fail by a combination of Al loss in forming the oxide scale and Al loss via interdiffusion with the substrate alloy. Comparisons of beta+gamma/gamma coating behavior are made to the oxidation of coated gamma+gamma-prime substrates, both ternary Ni-Cr-Al alloys and Mar-M 247-type alloys.

  19. Airborne gamma-ray spectrometry

    DEFF Research Database (Denmark)

    Hovgaard, Jens

    A new method - Noise Adjusted Singular Value Decomposition, NASVD - for processing gamma-ray spectra has been developed as part of a Ph.D. project. By using this technique one is able to decompose a large set of data - for example from airborne gamma-ray surveys - into a few spectral components. ...

  20. On $Z \\to \\gamma \\gamma$ decay and cancellation of axial anomaly in $Z \\to \\gamma \\gamma$ transition amplitude for massive fermions

    OpenAIRE

    Zhemchugov, E. V.

    2014-01-01

    $Z \\to \\gamma \\gamma$ decay amplitude is considered and proven to be zero due to properties of polarization vectors and Bose statistics. Triangular diagrams for a pseudoscalar $\\to \\gamma \\gamma$ and $Z \\to \\gamma \\gamma$ processes with massive fermions in the loop are explicitely calculated. In the Standard Model axial anomaly vanishes in the sum of these diagrams as Z boson is mixed with one of the Goldstone bosons.

  1. AGATA - Advanced Gamma Tracking Array

    CERN Document Server

    Akkoyun, S; Alikhani, B; Ameil, F; de Angelis, G; Arnold, L; Astier, A; Ataç, A; Aubert, Y; Aufranc, C; Austin, A; Aydin, S; Azaiez, F; Badoer, S; Balabanski, D L; Barrientos, D; Baulieu, G; Baumann, R; Bazzacco, D; Beck, F A; Beck, T; Bednarczyk, P; Bellato, M; Bentley, M A; Benzoni, G; Berthier, R; Berti, L; Beunard, R; Bianco, G Lo; Birkenbach, B; Bizzeti, P G; Bizzeti-Sona, A M; Blanc, F Le; Blasco, J M; Blasi, N; Bloor, D; Boiano, C; Borsato, M; Bortolato, D; Boston, A J; Boston, H C; Bourgault, P; Boutachkov, P; Bouty, A; Bracco, A; Brambilla, S; Brawn, I P; Brondi, A; Broussard, S; Bruyneel, B; Bucurescu, D; Burrows, I; Bürger, A; Cabaret, S; Cahan, B; Calore, E; Camera, F; Capsoni, A; Carrió, F; Casati, G; Castoldi, M; Cederwall, B; Cercus, J -L; Chambert, V; Chambit, M El; Chapman, R; Charles, L; Chavas, J; Clément, E; Cocconi, P; Coelli, S; Coleman-Smith, P J; Colombo, A; Colosimo, S; Commeaux, C; Conventi, D; Cooper, R J; Corsi, A; Cortesi, A; Costa, L; Crespi, F C L; Cresswell, J R; Cullen, D M; Curien, D; Czermak, A; Delbourg, D; Depalo, R; Descombes, T; Désesquelles, P; Detistov, P; Diarra, C; Didierjean, F; Dimmock, M R; Doan, Q T; Domingo-Pardo, C; Doncel, M; Dorangeville, F; Dosme, N; Drouen, Y; Duchêne, G; Dulny, B; Eberth, J; Edelbruck, P; Egea, J; Engert, T; Erduran, M N; Ertürk, S; Fanin, C; Fantinel, S; Farnea, E; Faul, T; Filliger, M; Filmer, F; Finck, Ch; de France, G; Gadea, A; Gast, W; Geraci, A; Gerl, J; Gernhäuser, R; Giannatiempo, A; Giaz, A; Gibelin, L; Givechev, A; Goel, N; González, V; Gottardo, A; Grave, X; Grȩbosz, J; Griffiths, R; Grint, A N; Gros, P; Guevara, L; Gulmini, M; Görgen, A; Ha, H T M; Habermann, T; Harkness, L J; Harroch, H; Hauschild, K; He, C; Hernández-Prieto, A; Hervieu, B; Hess, H; Hüyük, T; Ince, E; Isocrate, R; Jaworski, G; Johnson, A; Jolie, J; Jones, P; Jonson, B; Joshi, P; Judson, D S; Jungclaus, A; Kaci, M; Karkour, N; Karolak, M; Kaşkaş, A; Kebbiri, M; Kempley, R S; Khaplanov, A; Klupp, S; Kogimtzis, M; Kojouharov, I; Korichi, A; Korten, W; Kröll, Th; Krücken, R; Kurz, N; Ky, B Y; Labiche, M; Lafay, X; Lavergne, L; Lazarus, I H; Leboutelier, S; Lefebvre, F; Legay, E; Legeard, L; Lelli, F; Lenzi, S M; Leoni, S; Lermitage, A; Lersch, D; Leske, J; Letts, S C; Lhenoret, S; Lieder, R M; Linget, D; Ljungvall, J; Lopez-Martens, A; Lotodé, A; Lunardi, S; Maj, A; van der Marel, J; Mariette, Y; Marginean, N; Marginean, R; Maron, G; Mather, A R; Mȩczyński, W; Mendéz, V; Medina, P; Melon, B; Menegazzo, R; Mengoni, D; Merchan, E; Mihailescu, L; Michelagnoli, C; Mierzejewski, J; Milechina, L; Million, B; Mitev, K; Molini, P; Montanari, D; Moon, S; Morbiducci, F; Moro, R; Morrall, P S; Möller, O; Nannini, A; Napoli, D R; Nelson, L; Nespolo, M; Ngo, V L; Nicoletto, M; Nicolini, R; Noa, Y Le; Nolan, P J; Norman, M; Nyberg, J; Obertelli, A; Olariu, A; Orlandi, R; Oxley, D C; Özben, C; Ozille, M; Oziol, C; Pachoud, E; Palacz, M; Palin, J; Pancin, J; Parisel, C; Pariset, P; Pascovici, G; Peghin, R; Pellegri, L; Perego, A; Perrier, S; Petcu, M; Petkov, P; Petrache, C; Pierre, E; Pietralla, N; Pietri, S; Pignanelli, M; Piqueras, I; Podolyak, Z; Pouhalec, P Le; Pouthas, J; Pugnére, D; Pucknell, V F E; Pullia, A; Quintana, B; Raine, R; Rainovski, G; Ramina, L; Rampazzo, G; La Rana, G; Rebeschini, M; Recchia, F; Redon, N; Reese, M; Reiter, P; Regan, P H; Riboldi, S; Richer, M; Rigato, M; Rigby, S; Ripamonti, G; Robinson, A P; Robin, J; Roccaz, J; Ropert, J -A; Rossé, B; Alvarez, C Rossi; Rosso, D; Rubio, B; Rudolph, D; Saillant, F; Şahin, E; Salomon, F; Salsac, M -D; Salt, J; Salvato, G; Sampson, J; Sanchis, E; Santos, C; Schaffner, H; Schlarb, M; Scraggs, D P; Seddon, D; Şenyiğit, M; Sigward, M -H; Simpson, G; Simpson, J; Slee, M; Smith, J F; Sona, P; Sowicki, B; Spolaore, P; Stahl, C; Stanios, T; Stefanova, E; Stézowski, O; Strachan, J; Suliman, G; Söderström, P -A; Tain, J L; Tanguy, S; Tashenov, S; Theisen, Ch; Thornhill, J; Tomasi, F; Toniolo, N; Touzery, R; Travers, B; Triossi, A; Tripon, M; Tun-Lanoë, K M M; Turcato, M; Unsworth, C; Ur, C A; Valiente-Dobon, J J; Vandone, V; Vardaci, E; Venturelli, R; Veronese, F; Veyssiere, Ch; Viscione, E; Wadsworth, R; Walker, P M; Warr, N; Weber, C; Weisshaar, D; Wells, D; Wieland, O; Wiens, A; Wittwer, G; Wollersheim, H J; Zocca, F; Zamfir, N V; Ziȩbliński, M; Zucchiatti, A

    2011-01-01

    The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realization of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly-segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterization of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorith...

  2. Sterilization by gamma irradiation

    International Nuclear Information System (INIS)

    Since 1980 the National Institute of Nuclear Research counts with an Industrial Gamma Irradiator, for the sterilization of raw materials and finished products. Through several means has been promoted the use of this technology as alternative to conventional methods of sterilization as well as steam treatment and ethylene oxide. As a result of the made promotion this irradiator has come to its saturation limit being the sterilization irradiation one of the main services that National Institute of Nuclear Research offers to producer enterprises of disposable materials of medical use also of raw materials for the elaboration of cosmetic products and pharmaceuticals as well as dehydrated foods. It is presented the trend to the sterilization service by irradiation showed by the compilation data in a survey made by potential customers. (Author)

  3. Planetary gamma-ray spectroscopy

    International Nuclear Information System (INIS)

    The chemical composition of a planet can be inferred from the gamma rays escaping from its surface and can be used to study its origin and evolution. The measured intensities of certain gamma rays of specific energies can be used to determine the abundances of a number of elements. The major sources of these gamma-ray lines are the decay of natural radionuclides, reactions induced by energetic galactic-cosmic-ray particles, capture of low energy neutrons, and solar-proton-induced radioactivities. The fluxes of the more intense gamma-ray lines emitted from 30 elements were calculated using current nuclear data and existing models. The source strengths for neutron-capture reactions were modified from those previously used. The fluxes emitted from a surface of average lunar composition are reported for 288 gamma-ray lines. These theoretical fluxes have been used elsewhere to convert the data from the Apollo gamma-ray spectrometers to elemental abundances and can be used with results from future missions to map the concentrations of a number of elements over a planet's surface. Detection sensitivities for these elements are examined and applications of gamma-ray spectroscopy for future orbiters to Mars and other solar-system objects are discussed

  4. Planetary gamma-ray spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Reedy, R.C.

    1978-01-01

    The chemical composition of a planet can be inferred from the gamma rays escaping from its surface and can be used to study its origin and evolution. The measured intensities of certain gamma rays of specific energies can be used to determine the abundances of a number of elements. The major sources of these gamma-ray lines are the decay of natural radionuclides, reactions induced by energetic galactic-cosmic-ray particles, capture of low energy neutrons, and solar-proton-induced radioactivities. The fluxes of the more intense gamma-ray lines emitted from 30 elements were calculated using current nuclear data and existing models. The source strengths for neutron-capture reactions were modified from those previously used. The fluxes emitted from a surface of average lunar composition are reported for 288 gamma-ray lines. These theoretical fluxes have been used elsewhere to convert the data from the Apollo gamma-ray spectrometers to elemental abundances and can be used with results from future missions to map the concentrations of a number of elements over a planet's surface. Detection sensitivities for these elements are examined and applications of gamma-ray spectroscopy for future orbiters to Mars and other solar-system objects are discussed.

  5. Galactic plane gamma-radiation

    Science.gov (United States)

    Hartman, R. C.; Kniffen, D. A.; Thompson, D. J.; Fichtel, C. E.; Ogelman, H. B.; Tumer, T.; Ozel, M. E.

    1979-01-01

    Analysis of the SAS 2 data together with the COS B results shows that the distribution of galactic gamma-radiation has several similarities to that of other large-scale tracers of galactic structure. The radiation is primarily confined to a thin disc which exhibits offsets from b = 0 degrees similar to warping at radio frequencies. The principal distinction of the gamma-radiation is a stronger contrast in intensity between the region from 310 to 45 degrees in longitude and the regions away from the center that can be attributed to a variation in cosmic-ray density as a function of position in Galaxy. The diffuse galactic gamma-ray energy spectrum shows no significant variation in direction, and the spectrum seen along the plane is the same as that for the galactic component of the gamma-radiation at high altitudes. The uniformity of the galactic gamma-ray spectrum, the smooth decrease in intensity as a function of altitude, and the absence of any galactic gamma-ray sources at high altitudes indicate a diffuse origin for bulk of the galactic gamma-radiation rather than a collection of localized sources.

  6. $\\gamma\\gamma$ physics with the KLOE experiment

    CERN Document Server

    Archilli, F; Badoni, D; Balwierz, I; Bencivenni, G; Bini, C; Bloise, C; Bocci, V; Bossi, F; Branchini, P; Budano, A; Bulychjev, S A; Campana, P; Capon, G; Ceradini, F; Ciambrone, P; Czerwinski, E; Dane, E; De Lucia, E; De Robertis, G; De Santis, A; De Zorzi, G; Di Domenico, A; Di Donato, C; Domenici, D; Erriquez, O; Fanizzi, G; Felici, G; Fiore, S; Franzini, P; Gauzzi, P; Giovannella, S; Gonnella, F; Graziani, E; Happacher, F; Hoistad, B; Iarocci, E; Jacewicz, M; Johansson, T; Kulikov, V; Kupsc, A; Lee-Franzini, J; Loddo, F; Martemianov, M; Martini, M; Matsyuk, M; Messi, R; Miscetti, S; Morello, G; Moricciani, D; Moskal, P; Nguyen, F; Passeri, A; Patera, V; Longhi, I Prado; Ranieri, A; Santangelo, P; Sarra, I; Schioppa, M; Sciascia, B; Sciubba, A; Silarski, M; Taccini, C; Tortora, L; Venanzoni, G; Versaci, R; Wislicki, W; Wolke, M; Zdebik, J

    2011-01-01

    The processes $e^+e^-\\to e^+e^-X$, with $X$ being either the $\\eta$ meson or $\\pi^0\\pi^0$, are studied at DA$\\Phi$NE, with $e^+e^-$ beams colliding at $\\sqrt{s}\\simeq1$ GeV, below the $\\phi$ resonance peak. The data sample is from an integrated luminosity of 240 pb$^{-1}$, collected by the KLOE experiment without tagging of the outgoing $e^+e^-$. Preliminary results are presented on the observation of the $\\gamma\\gamma\\to\\eta$ process, with both $\\eta\\to\\pi^+\\pi^-\\pi^0$ and $\\eta\\to\\pi^0\\pi^0\\pi^0$ channels, and the evidence for $\\gamma\\gamma\\to\\pi^0\\pi^0$ production at low $\\pi^0\\pi^0$ invariant mass.

  7. Total Cross Section in $\\gamma\\gamma$ Collisions at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Todorova-Nová, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ewers, A; Extermann, Pierre; Fabre, M; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M

    2001-01-01

    The reaction e+e- -> e+e- gamma* gamma* -> e+e- hadrons for quasi-real photons is studied using data from root(s) = 183 GeV up to 202 GeV. Results on the total cross sections sigma(e+e- -> e+e- hadrons) and sigma(+e- gamma* gamma* -> e+e- hadrons) are given for the two-photon centre-of-mass energies 5 GeV < Wgammagamma < 185 GeV. The total cross section of two real photons is described by a Regge parametrisation. We observe a steeper rise with the two-photon centre-of-mass energy as compared to the hadron-hadron and the photon-proton cross sections. The data are also compared to the expectations of different theoretical models.

  8. Gamma-ray Pulsar Revolution

    OpenAIRE

    Caraveo, Patrizia A.

    2013-01-01

    Isolated Neutron Stars (INSs) were the first sources identified in the field of high-energy gamma-ray astronomy. At first, in the 70s, there were only two identified sources, the Crab and Vela pulsars. However, although few in number, these objects were crucial in establishing the very concept of a gamma-ray source. Moreover, they opened up significant discovery space both in the theoretical and phenomenological fronts. The need to explain the copious gamma-ray emission of these pulsars led t...

  9. Bonds futures: Delta? No gamma!

    OpenAIRE

    Henrard, Marc

    2006-01-01

    Bond futures are liquid but complex instruments. Here they are analysed in a one-factor Gaussian HJM model. The in-the-model delta and out-of-the-model delta and gamma are studied. An explicit formula is provided for in-the-model delta. The out-of-the-model delta and gamma are equivalent to partial derivatives with respect to discount factors. In particular cases the derivative can not be obtained by standard techniques. The same situations lead to cases where the gammas (second order partial...

  10. Gamma radiation from radio pulsars

    Science.gov (United States)

    Ruderman, Malvin

    1990-01-01

    The probable magnetospheric location and source of the gamma ray emission from some young radiopulsars is discussed. The suggested evolution of this emission as a function of pulsar period gives a diminished gamma-ray luminosity for a more rapidly spinning pre-Crab pulsar. A greatly enhanced one, similar to that of unidentified Cos B sources, is predicted for a slightly slower post-Vela pulsar, followed by a relatively rapid quenching of the gamma-ray luminosity at still longer periods. Possible anomalous exo-magnetospheric pulsed MeV and TeV-PeV radiation from the Crab pulsar is considered.

  11. 体积排阻色谱法测定低分子量肝素抗凝血因子Xa的活性%An assay for anti-factor Xa activity of low molecular weight heparins by high performance liquid size exclusion chromatography

    Institute of Scientific and Technical Information of China (English)

    张倩倩; 康经武

    2013-01-01

    发展了一种基于体积排阻色谱测定低分子量肝素(LMWH)抗凝血活性的方法.利用肝素与抗凝血酶Ⅲ(ATⅢ)结合后可增强ATⅢ对凝血因子Xa (FXa)抑制作用的原理,通过测定加入LMWH后FXa水解其生色底物产生对硝基苯胺(pNA)这一反应的抑制程度确定LMWH的活性.首先将含有一定浓度LMWH的缓冲溶液与ATⅢ溶液混合,然后依次加入FXa和生色底物,分别孵育一段时间.底物被FXa水解,产生游离的pNA.体积排阻色谱可将小分子产物pNA与其他大分子分离开,因而可以在pNA的最大吸收波长下得到高灵敏度的测定,并且不再受其他成分的干扰.该方法重复性好,灵敏度高,极大地减少了样品的消耗量,降低了成本,并且还可进行各种复杂样品(如血浆)中LMWH抗FXa活性的监测.%The "gold standard" assay for monitoring low molecular weight heparins (LMWHs) activity is the chromogenic-based anti-factor Xa assay.The methodology of an anti-factor Xa assay is that LMWH is added to a known amount of excess factor Xa and excess antithrombin.It will bind to antithrombin and form a triplet complex with factor Xa,inhibiting the activity of factor Xa.However,the residual factor Xa can still hydrolyze chromogenic peptide substrate,releasing the chromophore for photometric detection.The absorbance is inversely proportional to the amount of heparin/LMWH.The results are given in anticoagulant concentration in units/ mL of anti-factor Xa,such that high values indicate high levels of anticoagulation and low values indicate low levels of anticoagulation.Herein,a novel assay method for anti-FXa activity of LMWHs using high performance liquid size exclusion chromatography (SEC) is reported,in which antithrombin m (AT m) was diluted by the buffer solution contained LMWHs.Subsequently,exogenous FXa and p-nitroaniline coupled peptide substrate were added and incubated for a period,separately.The resulting mixture was separated based on size by SEC

  12. Diamond gamma dose rate monitor; Debitmetre gamma en diamant

    Energy Technology Data Exchange (ETDEWEB)

    Brambilla, A.; Chambaud, P.; Tromson, D.; Bergonzo, P.; Foulon, F.; Joffre, F. [CEA Saclay, Dept. d' Electronique et d' Instrumentation Nucleaire, LETI, 91 - Gif-sur-Yvette (France)

    1999-07-01

    CVD (chemical vapor deposition) diamond detectors for X and gamma dose rate monitoring have been fabricated and tested in the 1 mGy/h to 1 kGy/h range. They show excellent performances in terms of sensitivity and linearity. Radiation hardness measurement under 60-Co gamma rays have demonstrated long term stability for integrated doses up to 500 kGy. (authors)

  13. Search for the Exclusive Radiative Decays B -> rho gamma and B -> omega gamma

    CERN Document Server

    Aubert, Bernard; Gaillard, Jean-Marc; Hicheur, A; Karyotakis, Yu; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kral, J F; Le Clerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, Michael T; Shelkov, V G; Telnov, A V; Wenzel, W A; Harrison, T J; Hawkes, C M; Knowles, D J; O'Neale, S W; Penny, R C; Watson, A T; Watson, N K; Deppermann, T; Goetzen, K; Koch, H; Lewandowski, B; Peters, K; Schmücker, H; Steinke, M; Barlow, N R; Bhimji, W; Boyd, J T; Chevalier, N; Clark, P J; Cottingham, W N; MacKay, C; Wilson, F F; Abe, K; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Jolly, S; McKemey, A K; Blinov, V E; Bukin, A D; Buzykaev, A R; Golubev, V B; Ivanchenko, V N; Korol, A A; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Yushkov, A N; Best, D; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M A; McMahon, S; Stoker, D P; Buchanan, C; Chun, S; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Prell, S; Rahatlou, S; Raven, G; Schwanke, U; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Hart, P A; Kuznetsova, N P; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beringer, J; Eisner, A M; Grothe, M; Heusch, C A; Lockman, W S; Pulliam, T; Schalk, T L; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S M; Mancinelli, G; Meadows, B T; Sokoloff, M D; Barillari, T; Bloom, P; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; Van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Krishnamurthy, M; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Maly, E; Müller-Pfefferkorn, R; Otto, S; Schubert, Klaus R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Ferrag, S; T'Jampens, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Anjomshoaa, A; Bernet, R; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Tinslay, J; Falbo, M; Borean, C; Bozzi, C; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Zallo, A; Bagnasco, S; Buzzo, A; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Pastore, F C; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Bartoldus, R; Grenier, G J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Lacker, H M; Laplace, S; Le Diberder, F R; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Trincaz-Duvoid, S; Wormser, G; Bionta, R M; Brigljevic, V; Lange, D J; Van Bibber, K; Wright, D M; Bevan, A J; Fry, J R; Gabathuler, Erwin; Gamet, R; George, M; Kay, M; Payne, D J; Sloane, R J; Touramanis, C; Aspinwall, M L; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Morton, G W; Nash, J A; Sanders, P; Smith, D; Taylor, G P; Back, J J; Bellodi, G; Dixon, P; Harrison, P F; Potter, R J L; Shorthouse, H W; Strother, P; Vidal, P B; Cowan, G; Flächer, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, R J; Forti, A C; Jackson, F; Lafferty, G D; Lyon, A J; Savvas, N; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Lillard, V; Roberts, D A; Schieck, J; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Stängle, H; Willocq, S; Brau, B; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Milek, M; Patel, P M; Palombo, F; Bauer, J M; Cremaldi, L M; Eschenburg, V; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Hast, C; Taras, P; Rene, J A; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, Gallieno; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; LoSecco, J M; Alsmiller, J R G; Gabriel, T A; Brau, J E; Frey, R; Iwasaki, M; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; La Vaissière, C de; Del Buono, L; Hamon, O; Leruste, P; Ocariz, J; Pivk, M; Roos, L; Stark, J; Manfredi, P F; Re, V; Speziali, V; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Campagna, E

    2002-01-01

    A search for the exclusive radiative decays B->rho(770) gamma and B^0->omega(782) gamma is performed on a sample of 84 million BB-bar events collected by the BABAR detector at the PEP-II asymmetric e^+e^- collider. No significant signal is seen in any of the channels. We set preliminary upper limits of BR[B^0->rho^0 gamma] rho^+ gamma] omega gamma] rho gamma, we find the preliminary limit BR[B -> rho gamma] rho gamma]/BR[B-> K* gamma] < 0.047 at 90% Confidence Level.

  14. Gamma-ray-selected AGN

    Science.gov (United States)

    Giommi, Paolo

    2016-08-01

    The gamma-ray band is the most energetic part of the electromagnetic spectrum. As such it is also where selection effects are most severe, as it can only be reached by the most extreme non-thermal AGN. Blazars, with their emission dominated by non-thermal blue-shifted radiation arising in a relativistic jet pointed in the direction of the observer, naturally satisfy this though requirement. For this reason, albeit these sources are intrisically very rare (orders of magnitude less abundant than radio quiet AGN of the same optical magnitude) they almost completely dominate the extragalactic gamma-ray and very high energy sky. I will discuss the emission of different types of blazars and the selection effects that are at play in the gamma-ray band based on recent results from the current generation of gamma-ray astronomy satellites, ground-based Cherenkov telescopes, and Monte Carlo simulations.

  15. Study of the $e^+ e^- \\to Z\\gamma\\gamma \\to q\\overline{q}\\gamma\\gamma$ Process at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Todorova-Nová, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ewers, A; Extermann, Pierre; Fabre, M; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, M; Wang, X L; Wang, Z M; Weber, A; Weber, M; Wienemann, P; Wilkens, H; Wu, S X; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Ye, J B; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhu, G Y; Zhu, R Y; Zichichi, A; Zilizi, G; Zimmermann, B; Zöller, M

    2001-01-01

    The process e^+e^- -> Z gamma gamma -> q q~ gamma gamma$ is studied in 0.5\\,fb-1$ of data collected with the L3 detector at centre-of-mass energies between 130.1 GeV and 201.7 GeV. Cross sections are measured and found to be consistent with the Standard Model expectations. The study of the least energetic photon constrains the quartic gauge boson couplings to -0.008 GeV-2 < a_0/\\Lambda^2 < 0.005 GeV-2 and -0.007 GeV-2 < a_c/\\Lambda^2 < 0.011 GeV-2, at 95% confidence level.

  16. The GAMMA-400 Space Experiment

    Science.gov (United States)

    Bongi, M.

    2014-06-01

    GAMMA-400 is a new space experiment which will study gamma rays and cosmic rays from about 100 MeV up to some TeVs. The proposed instrument has an angular resolution ˜ 0.1 degrees at 10 GeV and better than ˜ 0.02 degrees above 100 GeV, and an energy resolution ˜ 1% at E > 100 GeV for gamma rays. With these characteristics the experiment will be able to contribute to the search for signatures of Dark Matter, and to the study of Galactic and ex-tragalactic gamma sources and diffuse emission. A large segmented calorimeter more than 25 X0 deep will allow the study of high-energy electrons, and the measurement of the flux of protons and nuclei up to the "knee" region.

  17. Comparative physical mapping of rice BAC clones linked to resistance genes Glh,Bph-3 and xa-5 in Oryza sativa L.and O.granulata Nees et Am.ex Watt.

    Institute of Scientific and Technical Information of China (English)

    XIONG Zhiyong; TAN Guangxuan; YOU Aiqing; HE Guangyuan; SHE Chaowen; LI Lijia; SONG Yunchun

    2004-01-01

    Oryza granulata Nees et Arn. ex Watt. is one of the three wild relatives of rice, which are the most valuable for study and utilization in China. In this study, the homology and physical locations of three rice resistance genes, Glh,Bph-3 and xa-5 are comparatively analyzed between O. sativa and O. granulata by Southern blotting and fluorescence in situ hybridization (FISH). The results of Southern blotting indicate that there exist homologous sequences of the tested RFLP markers in O. granulata. By using three bacterial artificial chromosome (BAC) clones scanned by the tested RFLP as probes, FISH signals are detected on both mitotic and pachytene chromosomes in O. sativa and O. granulata.Dual-color FISH demonstrates that two of the three BAC clones (14E16 and 38J9) are located on the short arm of the same chromosome pair in O. granulata. Additionally, colinearity is shown for the two clones between O. sativa and O.granulata. Another BAC clone 44B4 is located on the end of the short arm of other chromosome pair in these two species.Although the phylogenetic relationship between O. sativa and O. granulata is the most distinct in Oryza and these two species have evidently different biological features and ecological habits, the relative lengths and arm ratios of the detected chromosomes and the relative positions of the tested clone signals on chromosomes in O. granulata are quite similar to those in O. sativa.

  18. Gamma camera system

    International Nuclear Information System (INIS)

    The invention provides a composite solid state detector for use in deriving a display, by spatial coordinate information, of the distribution or radiation emanating from a source within a region of interest, comprising several solid state detector components, each having a given surface arranged for exposure to impinging radiation and exhibiting discrete interactions therewith at given spatially definable locations. The surface of each component and the surface disposed opposite and substantially parallel thereto are associated with impedence means configured to provide for each opposed surface outputs for signals relating the given location of the interactions with one spatial coordinate parameter of one select directional sense. The detector components are arranged to provide groupings of adjacently disposed surfaces mutually linearly oriented to exhibit a common directional sense of the spatial coordinate parameter. Means interconnect at least two of the outputs associated with each of the surfaces within a given grouping for collecting the signals deriving therefrom. The invention also provides a camera system for imaging the distribution of a source of gamma radiation situated within a region of interest

  19. Diamond gamma dose rate monitor

    International Nuclear Information System (INIS)

    CVD (chemical vapor deposition) diamond detectors for X and gamma dose rate monitoring have been fabricated and tested in the 1 mGy/h to 1 kGy/h range. They show excellent performances in terms of sensitivity and linearity. Radiation hardness measurement under 60-Co gamma rays have demonstrated long term stability for integrated doses up to 500 kGy. (authors)

  20. Notes on the gamma kernel

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole E.

    The density function of the gamma distribution is used as shift kernel in Brownian semistationary processes modelling the timewise behaviour of the velocity in turbulent regimes. This report presents exact and asymptotic properties of the second order structure function under such a model......, and relates these to results of von Karmann and Horwath. But first it is shown that the gamma kernel is interpretable as a Green’s function....

  1. Dark Matter Search Perspectives with GAMMA-400

    CERN Document Server

    Moiseev, A A; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Avanesov, G A; Bergstrom, L; Boezio, M; Bonvicini, V; Boyarchuk, K A; Dogiel, V A; Gusakov, Yu V; Fradkin, M I; Fuglesang, Ch; Hnatyk, B I; Kachanov, V A; Kaplin, V A; Kheymits, M D; Korepanov, V; Larsson, J; Leonov, A A; Longo, F; Maestro, P; Marrocchesi, P; Mazets, E P; Mikhailov, V V; Mocchiutti, E; Mori, N; Moskalenko, I; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Runtso, M F; Ryde, F; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Topchiev, N P; Vacchi, A; Vannuccini, E; Yurkin, Yu T; Zampa, N; Zarikashvili, V N; Zverev, V G

    2013-01-01

    GAMMA-400 is a future high-energy gamma-ray telescope, designed to measure the fluxes of gamma-rays and cosmic-ray electrons + positrons, which can be produced by annihilation or decay of dark matter particles, and to survey the celestial sphere in order to study point and extended sources of gamma-rays, measure energy spectra of Galactic and extragalactic diffuse gamma-ray emission, gamma-ray bursts, and gamma-ray emission from the Sun. GAMMA-400 covers the energy range from 100 MeV to ~3000 GeV. Its angular resolution is ~0.01 deg(Eg > 100 GeV), and the energy resolution ~1% (Eg > 10 GeV). GAMMA-400 is planned to be launched on the Russian space platform Navigator in 2019. The GAMMA-400 perspectives in the search for dark matter in various scenarios are presented in this paper

  2. Observation of B_s to phi gamma and Search for B_s to gamma gamma Decays at Belle

    CERN Document Server

    Wicht, J; Aihara, H; Arinstein, K; Aulchenko, V; Aushev, T; Bakich, A M; Balagura, V; Bay, A; Belous, K S; Bhardwaj, V; Bitenc, U; Bondar, A; Bozek, A; Brako, M; Browder, T E; Chang, cP; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chistov, R; Cho, I S; Choi, Y; Dalseno, J; Dash, M; Drutskoy, A; Eidelman, S; Gabyshev, N; Goldenzweig, P; Golob, B; Haba, J; Hayasaka, K; Hazumi, M; Heffernan, D; Hoshi, Y; Hou, W S; Hsiung, Y B; Hyun, H J; Iijima, T; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwasaki, Y; Kah, D H; Kaji, H; Kang, J H; Kapusta, P; Kawai, H; Kawasaki, T; Kichimi, H; Kim, H J; Kim, H O; Kim, S K; Kim, Y J; Kinoshita, K; Korpar, S; Krian, P; Kumar, R; Kuo, C C; Kwon, Y J; Lange, J S; Lee, J; Lee, z J S; Lee, S E; Lesiak, T; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; Mandl, F; McOnie, S; Medvedeva, T; Mitaroff, W A; Miyabayashi, K; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Mohapatra, D; Moloney, G R; Nakao, M; Natkaniec, Z; Nishida, S; Nitoh, O; Nozaki, T; Ogawa, S; Ohshima, T; Okuno, S; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Park, H; Park, K S; Pestotnik, R; Piilonen, L E; Sakai, Y; Schneider, O; Schümann, J; Schwartz, A J; Senyo, K; Sevior, M E; Shapkin, M; Shibuya, H; Shiu, J G; Shwartz, B; Singh, J B; Somov, A; Stani, S; Stari, M; Sumisawa, K; Sumiyoshi, T; Takasaki, F; Tamai, K; Tanaka, M; Taylor, G N; Teramoto, Y; Trabelsi, cK; Tsuboyama, T; Uehara, S; Ueno, K; Unno, Y; Uno, S; Ushiroda, Y; Usov, Yu; Varner, G; Vervink, K; Villa, S; Wang, C H; Wang, P; Wang, X L; Watanabe, Y; Won, E; Yabsley, B D; Yamashita, Y; Yamauchi, M; Yusa, Y; Zhang, Z P; Zhilich, V; Zupanc, A; Zwahlen, N

    2007-01-01

    We search for the radiative penguin decays B_s to phi gamma and B_s to gamma gamma in a 23.6 fb-1 data sample collected at the Upsilon(5S) resonance with the Belle detector at the KEKB e+e- asymmetric-energy collider. We observe for the first time a radiative penguin decay of the B_s meson in the B_s to phi gamma mode. No significant B_s to gamma gamma signal is observed.

  3. Search for the Radiative Penguin Decays B+ -> rho+ gamma, B0 -> rho0 gamma, and B0 -> omega gamma

    CERN Document Server

    Aubert, B; Boutigny, D; Couderc, F; Gaillard, J M; Hicheur, A; Karyotakis, Yu; Lees, J P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, Michael T; Shelkov, V G; Wenzel, W A; Barrett, M; Ford, K E; Harrison, T J; Hart, A J; Hawkes, C M; Morgan, S E; Watson, A T; Fritsch, M; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Wilson, F F; Çuhadar-Dönszelmann, T; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Thiessen, D; Khan, A; Kyberd, P; Teodorescu, L; Blinov, A E; Blinov, V E; Druzhinin, V P; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M A; Mommsen, R K; Röthel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Foulkes, S D; Gary, J W; Shen, B C; Wang, K; Del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Eisner, A M; Heusch, C A; Kroseberg, J; Lockman, W S; Nesom, G; Schalk, T; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S M; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Smith, J G; Zhang, J; Zhang, L; Chen, A; Harton, J L; Soffer, A; Toki, W H; Wilson, R J; Zeng, Q L; Altenburg, D; Brandt, T; Brose, J; Dickopp, M; Feltresi, E; Hauke, A; Lacker, H M; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Petzold, A; Schubert, J; Schubert, Klaus R; Schwierz, R; Spaan, B; Sundermann, J E; Bernard, D; Bonneaud, G R; Brochard, F; Grenier, P; Schrenk, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Bard, D J; Clark, P J; Lavin, D; Muheim, F; Playfer, S; Xie, Y; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Brandenburg, G; Chaisanguanthum, K S; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Nikolich, M B; Taylor, G P; Charles, M J; Grenier, G J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Yi, J; Biasini, M; Covarelli, R; Pioppi, M; Davier, M; Giroux, X; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F R; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Chavez, C A; Coleman, J P; Forster, I J; Fry, J R; Gabathuler, Erwin; Gamet, R; Hutchcroft, D E; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Mohanty, G B; Cowan, G; Flack, R L; Flächer, H U; Green, M G; Jackson, P S; McMahon, T R; Ricciardi, S; Salvatore, F; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Lafferty, G D; Lyon, A J; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Stängle, H; Willocq, S; Cowan, R; Sciolla, G; Sekula, S J; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L M; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Zhao, H W; Brunet, S; Côté, D; Taras, P; Nicholson, H; Cavallo, N; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M; Bulten, H; Raven, G; Snoek, H L; Wilden, L; Jessop, C P; LoSecco, J M; Allmendinger, T; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Rahimi, A M; Ter-Antonian, R; Wong, Q K; Brau, J E; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; La Vaissière, C de; Del Buono, L; Hamon, O; John, M J J; Leruste, P; Malcles, J; Ocariz, J; Pivk, M; Roos, L; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martínez-Vidal, F; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lau, Y P; Lü, C; Miftakov, V; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai-Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B J; Geddes, N I; Gopal, G P; Olaiya, E O; Aleksan, Roy; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel de Monchenault, G; Kozanecki, Witold; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yéche, C; Zito, M; Purohit, M V; Weidemann, A W; Wilson, J R; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmüller, O L; Claus, R; Convery, M R; Cristinziani, M; De Nardo, Gallieno; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W M; Elsen, E E; Fan, S; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hast, C; Hrynóva, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Lüth, V; Lynch, H L; Marsiske, H; Messner, R; Müller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Vavra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Young, C C; Burchat, Patricia R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bóna, M; Gallo, F; Gamba, D; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R V; Roney, J M; Sobie, R J; Band, H R; Cheng, B; Dasu, S; Datta, M; Eichenbaum, A M; Graham, M; Hollar, J J; Johnson, J R; Kutter, P E; Li, H; Liu, R; Mihályi, A; Mohapatra, A K; Pan, Y; Prepost, R; Tan, P; Von Wimmersperg-Töller, J H; Wu, J; Wu, S L; Yu, Z; Greene, M G; Neal, H

    2004-01-01

    A search for the decays B --> rho(770) gamma and B0 --> omega(782)gamma is performed on a sample of 211 million Y(4S)->BBbar events collected by the BABAR detector at the PEP-II asymmetric-energy e+e- storage ring. No evidence for the decays is seen. We set the following limits on the individual branching fractions BF(B --> rho+ gamma) rho0 gamma) omega gamma) (rho/omega) gamma]<1.2 x 10^-6 and constrain V_td/V_ts< 0.19 at the 90% C.L.

  4. GammaModeler 3-D gamma-ray imaging technology

    International Nuclear Information System (INIS)

    The 3-D GammaModelertrademark system was used to survey a portion of the facility and provide 3-D visual and radiation representation of contaminated equipment located within the facility. The 3-D GammaModelertrademark system software was used to deconvolve extended sources into a series of point sources, locate the positions of these sources in space and calculate the 30 cm. dose rates for each of these sources. Localization of the sources in three dimensions provides information on source locations interior to the visual objects and provides a better estimate of the source intensities. The three dimensional representation of the objects can be made transparent in order to visualize sources located within the objects. Positional knowledge of all the sources can be used to calculate a map of the radiation in the canyon. The use of 3-D visual and gamma ray information supports improved planning decision-making, and aids in communications with regulators and stakeholders

  5. AGATA - Advanced GAmma Tracking Array

    Energy Technology Data Exchange (ETDEWEB)

    Akkoyun, S. [Department of Physics, Faculty of Science, Ankara University, 06100 Tandogan, Ankara (Turkey); Algora, A. [IFIC, CSIC-Universitat de Valencia, E-46980 Paterna (Spain); Alikhani, B. [IKP, TU Darmstadt, Schlossgartenstrasse 9, D-64289 Darmstadt (Germany); Ameil, F. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Angelis, G. de [INFN Laboratori Nazionali di Legnaro, IT-35020 Padova (Italy); Arnold, L. [Universite de Strasbourg, IPHC, 23 rue du Loess, 67037 Strasbourg (France); CNRS, UMR 7178, 67037 Strasbourg (France); Astier, A. [CSNSM, CNRS, IN2P3, Universite Paris-Sud, F-91405 Orsay (France); Atac, A. [Department of Physics, Faculty of Science, Ankara University, 06100 Tandogan, Ankara (Turkey); Department of Physics and Astronomy, Uppsala University, Uppsala (Sweden); Royal Institute of Technology, SE-10691 Stockholm (Sweden); Aubert, Y. [IPNO, CNRS/IN2P3, Universite Paris-Sud, F-91406 Orsay (France); Aufranc, C. [Universite de Lyon, Universite Lyon 1, CNRS-IN2P3, Institut de Physique Nucleaire de Lyon, F-69622 Villeurbanne (France); Austin, A. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Aydin, S. [INFN Sezione di Padova, IT-35131 Padova (Italy); Azaiez, F. [IPNO, CNRS/IN2P3, Universite Paris-Sud, F-91406 Orsay (France); Badoer, S. [INFN Laboratori Nazionali di Legnaro, IT-35020 Padova (Italy); Balabanski, D.L. [Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia (Bulgaria); Barrientos, D. [IFIC, CSIC-Universitat de Valencia, E-46980 Paterna (Spain); and others

    2012-03-11

    The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation {gamma}-ray spectrometer. AGATA is based on the technique of {gamma}-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a {gamma} ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of {gamma}-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer.

  6. Extragalactic Gamma-Ray Astrophysics

    CERN Document Server

    CERN. Geneva

    2016-01-01

    During the last decades, various classes of radio-loud active galactic nuclei have been established as sources of high-energy radiation extending over a very broad range from soft gamma-rays (photon energies E~MeV) up to very-high-energy gamma-rays (E>100 GeV). These include blazars of different types, as well as young and evolved radio galaxies. The observed gamma-ray emission from such implies efficient particle acceleration processes taking place in highly magnetized and relativistic jets produced by supermassive black holes, processes that have yet to be identified and properly understood. In addition, nearby starforming and starburst galaxies, some of which host radio-quiet Seyfert-type nuclei, have been detected in the gamma-ray range as well. In their cases, the observed gamma-ray emission is due to non-thermal activity in the interstellar medium, possibly including also a contribution from accretion disks and nuclear outflows. Finally, the high-energy emission from clusters of galaxies remains elusive...

  7. Quality assurance for gamma knives

    Energy Technology Data Exchange (ETDEWEB)

    Jones, E.D.; Banks, W.W.; Fischer, L.E. [Lawrence Livermore National Lab., CA (United States)

    1995-09-01

    This report describes and summarizes the results of a quality assurance (QA) study of the Gamma Knife, a nuclear medical device used for the gamma irradiation of intracranial lesions. Focus was on the physical aspects of QA and did not address issues that are essentially medical, such as patient selection or prescription of dose. A risk-based QA assessment approach was used. Sample programs for quality control and assurance are included. The use of the Gamma Knife was found to conform to existing standards and guidelines concerning radiation safety and quality control of external beam therapies (shielding, safety reviews, radiation surveys, interlock systems, exposure monitoring, good medical physics practices, etc.) and to be compliant with NRC teletherapy regulations. There are, however, current practices for the Gamma Knife not covered by existing, formalized regulations, standards, or guidelines. These practices have been adopted by Gamma Knife users and continue to be developed with further experience. Some of these have appeared in publications or presentations and are slowly finding their way into recommendations of professional organizations.

  8. Quality assurance for gamma knives

    International Nuclear Information System (INIS)

    This report describes and summarizes the results of a quality assurance (QA) study of the Gamma Knife, a nuclear medical device used for the gamma irradiation of intracranial lesions. Focus was on the physical aspects of QA and did not address issues that are essentially medical, such as patient selection or prescription of dose. A risk-based QA assessment approach was used. Sample programs for quality control and assurance are included. The use of the Gamma Knife was found to conform to existing standards and guidelines concerning radiation safety and quality control of external beam therapies (shielding, safety reviews, radiation surveys, interlock systems, exposure monitoring, good medical physics practices, etc.) and to be compliant with NRC teletherapy regulations. There are, however, current practices for the Gamma Knife not covered by existing, formalized regulations, standards, or guidelines. These practices have been adopted by Gamma Knife users and continue to be developed with further experience. Some of these have appeared in publications or presentations and are slowly finding their way into recommendations of professional organizations

  9. Effect of Re in {gamma} phase, {gamma}{sup '} phase and {gamma}/{gamma}{sup '} interface of Ni-based single-crystal superalloys

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Tao, E-mail: zhutao2003@sohu.com [Central Iron and Steel Research Institute, Beijing 100081 (China); Wang Chongyu, E-mail: cywang@mail.tsinghua.edu.cn [Central Iron and Steel Research Institute, Beijing 100081 (China)] [Department of Physics, Tsinghua University, Beijing 100084 (China)] [International Centre for Materials Physics, Chinese Academy of Sciences, Shenyang 110016 (China); Gan Yong, E-mail: gany@cisri.com.cn [Central Iron and Steel Research Institute, Beijing 100081 (China)

    2010-04-15

    Molecular dynamics (MD) within the framework of the embedded atom method and the first-principles discrete variational method (DVM) are both used to study the effect of Re in the {gamma} phase, the {gamma}{sup '} phase and the {gamma}/{gamma}{sup '} interface of Ni-based single-crystal superalloys. From the MD relaxation it is found that the {gamma}/{gamma}{sup '} interface only has two atomic configurations, i.e. a coherent region and a misfit dislocation region, and the 'cage-like' misfit dislocation networks, consist of <110>{l_brace}0 0 1{r_brace} edge dislocations winding over the precipitate phase. The MD results also show that the substitution atom Re stabilizes both the {gamma} phase and the {gamma}{sup '} phase, and influences the degree of mismatch between {gamma} and {gamma}{sup '}. From the simulation results we find that Re atoms have a tendency to cluster in both the {gamma} phase and the {gamma}{sup '} phase. Based on the MD simulation we have chosen six clusters of the {gamma}/{gamma}{sup '} interface for the DVM study, in which the interatomic energy, the charge distribution, the partial density of states and the electron density difference are all calculated. It is found that a Re atom occupying either a Ni site in the {gamma} phase or an Al site in the {gamma}{sup '} phase can strongly enhance the bonding strength between Re and its nearest neighboring atoms, suggesting that the substitution atom Re will influence dislocation motion along the {gamma}/{gamma}{sup '} interface.

  10. Mirror matter admixtures in K_S to gamma gamma

    CERN Document Server

    Sánchez-Colón, G; Sanchez-Colon, Gabriel; Garcia, Augusto

    2006-01-01

    The latest measurement of the K_S to gamma gamma branching ratio clearly shows an enhancement over the current theoretical prediction. As in other K and B meson decays, this invites to consider the possibility of the contribution of new physics. We study a particular form of the latter, which may be referred to as manifest mirror symmetry. The experimental data are described using previously determined values for the mixing angles of the admixtures of mirror matter in ordinary hadrons and by assuming that for pi^0, eta, eta', the mirror decay amplitudes have the same magnitudes as their ordinary counterparts.

  11. FEL system for gamma-gamma collider at TESLA

    International Nuclear Information System (INIS)

    The present paper contains the results of optimization of the free electron laser for the gamma-gamma collider at TESLA. A superconducting linear accelerator, similar to the TTF (TESLA Test Facility) accelerator, produces a driving electron beam for the FEL. The MOPA FEL scheme is studied when the radiation from a master oscillator is amplified in the FEL amplifier with tapered undulator. The FEL produces a radiation of TW level with a wavelength of 1 μm. Optimization of the FEL amplifier is performed with a three-dimensional, time-dependent simulation code FAST

  12. Free electron laser for gamma-gamma collider at TESLA

    International Nuclear Information System (INIS)

    The present paper contains the results of optimization of the free electron laser for the gamma-gamma collider at TESLA. A superconducting linear accelerator, similar to the TESLA test facility (TTF) accelerator, produces a driving electron beam for the FEL. The MOPA FEL scheme is studied when the radiation from a master oscillator is amplified in the FEL amplifier with tapered undulator. The FEL produces the radiation of TW level with a wavelength of 1 μm. Optimization of the FEL amplifier is performed with three-dimensional, time-dependent simulation code FAST

  13. Single sneutrino production in $\\gamma\\gamma$ collisions

    CERN Document Server

    Chaichian, Masud; Roy, S; Yu, Z H

    2001-01-01

    We study the single production of sneutrinos with two leptons (or jets) via $\\gamma\\gamma$ collision in an R-parity ($R_{p}$) violating supersymmetric model. The subsequent decays of the sneutrino are also considered. The single production of sneutrinos may provide a significant test of supersymmetry and $R_p$-violation with flavour conserving and flavour changing final states. If such processes coming from $R_p$ violation are not detected, the parameter space of the model will be strongly constrained at the future Linear Collider.

  14. The neutron–gamma Feynman variance to mean approach: Gamma detection and total neutron–gamma detection (theory and practice)

    Energy Technology Data Exchange (ETDEWEB)

    Chernikova, Dina, E-mail: dina@nephy.chalmers.se [Chalmers University of Technology, Department of Applied Physics, Nuclear Engineering, Fysikgården 4, SE-412 96 Göteborg (Sweden); Axell, Kåre [Chalmers University of Technology, Department of Applied Physics, Nuclear Engineering, Fysikgården 4, SE-412 96 Göteborg (Sweden); Swedish Radiation Safety Authority, SE-171 16 Stockholm (Sweden); Avdic, Senada [University of Tuzla, Department of Physics, 75000 Tuzla, Bosnia and Herzegovina (Bosnia and Herzegovina); Pázsit, Imre; Nordlund, Anders [Chalmers University of Technology, Department of Applied Physics, Nuclear Engineering, Fysikgården 4, SE-412 96 Göteborg (Sweden); Allard, Stefan [Chalmers University of Technology, Department of Chemical and Biological Engineering, Nuclear Chemistry and Industrial Materials Recycling, Kemivagen 4, SE-412 96 Göteborg (Sweden)

    2015-05-11

    Two versions of the neutron–gamma variance to mean (Feynman-alpha method or Feynman-Y function) formula for either gamma detection only or total neutron–gamma detection, respectively, are derived and compared in this paper. The new formulas have particular importance for detectors of either gamma photons or detectors sensitive to both neutron and gamma radiation. If applied to a plastic or liquid scintillation detector, the total neutron–gamma detection Feynman-Y expression corresponds to a situation where no discrimination is made between neutrons and gamma particles. The gamma variance to mean formulas are useful when a detector of only gamma radiation is used or when working with a combined neutron–gamma detector at high count rates. The theoretical derivation is based on the Chapman–Kolmogorov equation with the inclusion of general reactions and corresponding intensities for neutrons and gammas, but with the inclusion of prompt reactions only. A one energy group approximation is considered. The comparison of the two different theories is made by using reaction intensities obtained in MCNPX simulations with a simplified geometry for two scintillation detectors and a {sup 252}Cf-source. In addition, the variance to mean ratios, neutron, gamma and total neutron–gamma are evaluated experimentally for a weak {sup 252}Cf neutron–gamma source, a {sup 137}Cs random gamma source and a {sup 22}Na correlated gamma source. Due to the focus being on the possibility of using neutron–gamma variance to mean theories for both reactor and safeguards applications, we limited the present study to the general analytical expressions for Feynman-alpha formulas.

  15. Beta-gamma discriminator circuit

    International Nuclear Information System (INIS)

    The major difficulty encountered in the determination of beta-ray dose in field conditions is generally the presence of a relatively high gamma-ray component. Conventional dosimetry instruments use a shield on the detector to estimate the gamma-ray component in comparison with the beta-ray component. More accurate dosimetry information can be obtained from the measured beta spectrum itself. At Los Alamos, a detector and discriminator circuit suitable for use in a portable spectrometer have been developed. This instrument will discriminate between gammas and betas in a mixed field. The portable package includes a 256-channel MCA which can be programmed to give a variety of outputs, including a spectral display, and may be programmed to read dose directly

  16. Scintillation counter, maximum gamma aspect

    International Nuclear Information System (INIS)

    A scintillation counter, particularly for counting gamma ray photons, includes a massive lead radiation shield surrounding a sample-receiving zone. The shield is disassembleable into a plurality of segments to allow facile installation and removal of a photomultiplier tube assembly, the segments being so constructed as to prevent straight-line access of external radiation through the shield into radiation-responsive areas. Provisions are made for accurately aligning the photomultiplier tube with respect to one or more sample-transmitting bores extending through the shield to the sample receiving zone. A sample elevator, used in transporting samples into the zone, is designed to provide a maximum gamma-receiving aspect to maximize the gamma detecting efficiency. (U.S.)

  17. Gamma irradiators for radiation processing

    International Nuclear Information System (INIS)

    Radiation technology is one of the most important fields which the IAEA supports and promotes, and has several programmes that facilitate its use in the developing Member States. In view of this mandate, this Booklet on 'Gamma Irradiators for Radiation Processing' is prepared which describes variety of gamma irradiators that can be used for radiation processing applications. It is intended to present description of general principles of design and operation of the gamma irradiators available currently for industrial use. It aims at providing information to industrial end users to familiarise them with the technology, with the hope that the information contained here would assist them in selecting the most optimum irradiator for their needs. Correct selection affects not only the ease of operation but also yields higher efficiency, and thus improved economy. The Booklet is also intended for promoting radiation processing in general to governments and general public

  18. Terrestrial gamma-ray flashes

    Energy Technology Data Exchange (ETDEWEB)

    Marisaldi, Martino, E-mail: marisaldi@iasfbo.inaf.it [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy); Fuschino, Fabio; Labanti, Claudio [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy); Tavani, Marco [INAF-IASF Roma, Via Fosso del Cavaliere 100, I-00133 Roma (Italy); Argan, Andrea [INAF, Viale del Parco Mellini 84, 00136 Roma (Italy); Del Monte, Ettore [INAF-IASF Roma, Via Fosso del Cavaliere 100, I-00133 Roma (Italy); Longo, Francesco; Barbiellini, Guido [Dipartimento di Fisica Università di Trieste and INFN Trieste, via A. Valerio 2, I-34127 Trieste (Italy); Giuliani, Andrea [INAF-IASF Milano, Via Bassini 15, I-20133 Milano (Italy); Trois, Alessio [INAF Osservatorio Astronomico di Cagliari, loc. Poggio dei Pini, strada 54, I-09012 Capoterra (Italy); Bulgarelli, Andrea; Gianotti, Fulvio; Trifoglio, Massimo [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy)

    2013-08-21

    Lightning and thunderstorm systems in general have been recently recognized as powerful particle accelerators, capable of producing electrons, positrons, gamma-rays and neutrons with energies as high as several tens of MeV. In fact, these natural systems turn out to be the highest energy and most efficient natural particle accelerators on Earth. Terrestrial Gamma-ray Flashes (TGFs) are millisecond long, very intense bursts of gamma-rays and are one of the most intriguing manifestation of these natural accelerators. Only three currently operative missions are capable of detecting TGFs from space: the RHESSI, Fermi and AGILE satellites. In this paper we review the characteristics of TGFs, including energy spectrum, timing structure, beam geometry and correlation with lightning, and the basic principles of the associated production models. Then we focus on the recent AGILE discoveries concerning the high energy extension of the TGF spectrum up to 100 MeV, which is difficult to reconcile with current theoretical models.

  19. Zeptosecond $\\gamma$-ray pulses

    CERN Document Server

    Klaiber, Michael; Keitel, Christoph H

    2007-01-01

    High-order harmonic generation (HHG) in the relativistic regime is employed to obtain zeptosecond pulses of $\\gamma$-rays. The harmonics are generated from atomic systems in counterpropagating strong attosecond laser pulse trains of linear polarization. In this setup recollisions of the ionized electrons can be achieved in the highly relativistic regime via a reversal of the commonly deteriorating drift and without instability of the electron dynamics such as in a standing laser wave. As a result, coherent attosecond $\\gamma$-rays in the 10 MeV energy range as well as coherent zeptosecond $\\gamma$-ray pulses of MeV photon energy for time-resolved nuclear spectroscopy become feasible.

  20. Design and Performance of the GAMMA-400 Gamma-Ray Telescope for the Dark Matter Searches

    CERN Document Server

    Galper, A M; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Boezio, M; Bonvicini, V; Boyarchuk, K A; Fradkin, M I; Gusakov, Yu V; Kaplin, V A; Kachanov, V A; Kheymits, M D; Leonov, A A; Longo, F; Mazets, E P; Maestro, P; Marrocchesi, P; Mereminskiy, I A; Mikhailov, V V; Moiseev, A A; Mocchiutti, E; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Picozza, P; Rodin, V G; Runtso, M F; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Topchiev, N P; Vacchi, A; Vannuccini, E; Yurkin, Yu T; Zampa, N; Zverev, V G; Zirakashvili, V N

    2012-01-01

    The GAMMA-400 gamma-ray telescope is designed to measure the fluxes of gamma rays and cosmic-ray electrons + positrons, which can be produced by annihilation or decay of the dark matter particles, as well as to survey the celestial sphere in order to study point and extended sources of gamma rays, measure energy spectra of Galactic and extragalactic diffuse gamma-ray emission, gamma-ray bursts, and gamma-ray emission from the Sun. The GAMMA-400 covers the energy range from 100 MeV to 3000 GeV. Its angular resolution is ~0.01 deg (E{\\gamma} > 100 GeV), the energy resolution ~1% (E{\\gamma} > 10 GeV), and the proton rejection factor ~10E6. GAMMA-400 will be installed on the Russian space platform Navigator. The beginning of observations is planned for 2018.

  1. Design and Performance of the GAMMA-400 Gamma-Ray Telescope for Dark Matter Searches

    Science.gov (United States)

    Galper, A. M.; Adriani, O.; Aptekar, R. L.; Arkhangelskaja, I. V.; Arkhangelskiy, A. I.; Boezio, M.; Bonvicini, V.; Boyarchuk, K. A.; Fradkin, M. I.; Gusakov, Yu V.; Kaplin, V. A.; Kachanov, V. A.; Kheymits, M. D.; Leonov, A. A.; Longo, F.; Mazets, E. P.; Maestro, P.; Marrocchesi, P.; Mereminskiy, I. A.; Mikhailov, V. V.; Mocchiutti, E.; Moiseev, A. A.; Mori, N.; Moskalenko, I. V.; Naumov, P. Yu

    2012-01-01

    The GAMMA-400 gamma-ray telescope is designed to measure the fluxes of gamma-rays and cosmic-ray electrons (+) positrons, which can be produced by annihilation or decay of the dark matter particles, as well as to survey the celestial sphere in order to study point and extended sources of gamma-rays, measure energy spectra of Galactic and extragalactic diffuse gamma-ray emission, gamma-ray bursts, and gamma-ray emission from the Sun. GAMMA-400 covers the energy range from 100 MeV to 3000 GeV. Its angular resolution is approximately 0.01deg (E(sub gamma) greater than 100 GeV), the energy resolution approximately 1% (E(sub gamma) greater than 10 GeV), and the proton rejection factor approximately 10(exp 6). GAMMA-400 will be installed on the Russian space platform Navigator. The beginning of observations is planned for 2018.

  2. Dispersive treatment of $K_S\\to\\gamma\\gamma$ and $K_S\\to\\gamma\\ell^+\\ell^-$

    CERN Document Server

    Colangelo, Gilberto; Tunstall, Lewis C

    2016-01-01

    We analyse the rare kaon decays $K_S \\to \\gamma\\gamma$ and $K_S \\to \\gamma\\ell^+\\ell^-$ $(\\ell = e \\mbox{ or } \\mu)$ in a dispersive framework in which the weak Hamiltonian carries momentum. Our analysis extends predictions from lowest order $SU(3)_L\\times SU(3)_R$ chiral perturbation theory ($\\chi$PT$_3$) to fully account for effects from final-state interactions, and is free from ambiguities associated with extrapolating the kaon off-shell. Given input from $K_S \\to \\pi\\pi$ and $\\gamma\\gamma^{(*)}\\to\\pi\\pi$, we solve the once-subtracted dispersion relations numerically to predict the rates for $K_S \\to \\gamma\\gamma$ and $K_S \\to \\gamma\\ell^+\\ell^-$. In the leptonic modes, we find sizeable corrections to the $\\chi$PT$_3$ predictions for the integrated rates.

  3. Gamma-ray Imaging Methods

    Energy Technology Data Exchange (ETDEWEB)

    Vetter, K; Mihailescu, L; Nelson, K; Valentine, J; Wright, D

    2006-10-05

    In this document we discuss specific implementations for gamma-ray imaging instruments including the principle of operation and describe systems which have been built and demonstrated as well as systems currently under development. There are several fundamentally different technologies each with specific operational requirements and performance trade offs. We provide an overview of the different gamma-ray imaging techniques and briefly discuss challenges and limitations associated with each modality (in the appendix we give detailed descriptions of specific implementations for many of these technologies). In Section 3 we summarize the performance and operational aspects in tabular form as an aid for comparing technologies and mapping technologies to potential applications.

  4. Gamma-ray burst spectra

    Science.gov (United States)

    Teegarden, B. J.

    1982-01-01

    A review of recent results in gamma-ray burst spectroscopy is given. Particular attention is paid to the recent discovery of emission and absorption features in the burst spectra. These lines represent the strongest evidence to date that gamma-ray bursts originate on or near neutron stars. Line parameters give information on the temperature, magnetic field and possibly the gravitational potential of the neutron star. The behavior of the continuum spectrum is also discussed. A remarkably good fit to nearly all bursts is obtained with a thermal-bremsstrahlung-like continuum. Significant evolution is observed of both the continuum and line features within most events.

  5. Nuclear fuel microsphere gamma analyzer

    Science.gov (United States)

    Valentine, Kenneth H.; Long, Jr., Ernest L.; Willey, Melvin G.

    1977-01-01

    A gamma analyzer system is provided for the analysis of nuclear fuel microspheres and other radioactive particles. The system consists of an analysis turntable with means for loading, in sequence, a plurality of stations within the turntable; a gamma ray detector for determining the spectrum of a sample in one section; means for analyzing the spectrum; and a receiver turntable to collect the analyzed material in stations according to the spectrum analysis. Accordingly, particles may be sorted according to their quality; e.g., fuel particles with fractured coatings may be separated from those that are not fractured, or according to other properties.

  6. Measurement of resonance production in the reactions. gamma. gamma. yields. pi. sup 0. pi. sup 0 and. gamma. gamma. yields. pi. sup 0. eta

    Energy Technology Data Exchange (ETDEWEB)

    Oest, T.; Greenshaw, T.; Hagemann, J.; Heinzelmann, G.; Kleinwort, C.; Kuhlen, M.; Naroska, B.; Ould-Saada, F.; Pitzl, D.; Schneekloth, U.; Weber, G. (Hamburg Univ. (Germany, F.R.). 2. Inst. fuer Experimentalphysik); Olsson, J.; Bartel, W.; Felst, R.; Haidt, D.; Kado, H.; Knies, G.; Krehbiel, H.; Magnussen, N.; Meinke, R.; Ramcke, R.; Schmidt, D.; Steffen, P. (Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany, F.R.)); Allison, J.; Barlow, R.J.; Chrin, J.; Duerdoth, I.P.; Loebinger, F.K.; Macbeth, A.A.; Murphy, P.G.; Stephens, K. (Manchester Univ. (UK)); Ambrus, K.; Bethke, S.; Dieckmann, A.; Eckerlin, G.; Elsen, E.; Heintze, J.; Hellenbrand, K.H.; Komamiya, S.; Krogh, J. v.; Rieseberg, H.; Smolik, L.; Spitzer, J.; Wagner, A.; Zimmer, M. (Heidelberg Univ. (Germany, F.R.). Physikalisches Inst.); Bowdery, C.K.; Finch, A.J.; Foster, F.; Hughes, G.; Nye, J.M.; Walker, I.W. (Lancaster Univ. (UK)); Cartwright, S.L.; Clarke, D.; Marshall, R.; Middleton, R.P. (Rutherford Appleton L; JADE Collaboration

    1990-07-01

    Resonance production in the {gamma}{gamma} reactions e{sup +}e{sup -}{yields}e{sup +}e{sup -}{pi}{sup 0}{pi}{sup 0} and e{sup +}e{sup -}{yields}e{sup +}e{sup -}{pi}{sup 0}{eta} has been studied with the JADE detector at PETRA. The decay widths into {gamma}{gamma} of the f{sub 2}(1270), {alpha}{sub 0}(980) and {alpha}{sub 2}(1320) were measured to be {Gamma}{sub {gamma}{gamma}}(f{sub 2}(1270))=3.19{plus minus}0.09(+.22-0.38) keV, {Gamma}{sub {gamma}{gamma}}(a{sub 0}(980))=0.28{plus minus}0.04{plus minus}0.10 keV/BR(a{sub 0}(980){yields}{pi}{sup 0}{eta}) and {Gamma}{sub {gamma}{gamma}}(a{sub 2}(1320))=1.01{plus minus}0.14{plus minus}0.22 keV. For the f{sub 0}(975) and f{sub 4}(2050) upper limits of the widths were obtained, {Gamma}{sub {gamma}{gamma}}(f{sub 0}(975))<0.6 keV and {Gamma}{sub {gamma}{gamma}}(f{sub 4}(2050))<1.1 keV, both at the 95% C.L. Assumming that the spin 0 background under the f{sub 2}(1270) is small, the f{sub 2}(1270) was found to be produced exclusively in a helicity 2 state. The helicity 0 contribution is <15% at the 95% C.L.. The cross section for {gamma}{gamma}{yields}{pi}{sup 0}{pi}{sup 0} in the mass range 2.0-3.5 GeV/c{sup 2} was measured for the first time. Since the cross section for {gamma}{gamma}{yields}{pi}{sup +}{pi}{sup -} is a factor {proportional to}2 larger, {pi}{pi} production in this range can be interpreted as taking place via isospin 0 production. (orig.).

  7. Production of high-energy colliding. gamma gamma. and. gamma. e beams with a high luminosity at VLEPP accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Tel' nov, V.I.

    1981-11-05

    Colliding ..gamma gamma.. and ..gamma..e beams with an energy and luminosity of the same order of magnitude as for e/sup +/e/sup -/ beams can be produced by scattering a laser light at the accelerators with colliding e/sup +/e/sup -/ beams with an energy > or approx. =100 GeV. Such accelerators are currently in the design stage.

  8. QCD and $\\gamma\\,\\gamma$ studies at FCC-ee

    CERN Document Server

    Skands, Peter

    2016-01-01

    The Future Circular Collider (FCC) is a post-LHC project aiming at searches for physics beyond the SM in a new 80--100~km tunnel at CERN. Running in its first phase as a very-high-luminosity electron-positron collider (FCC-ee), it will provide unique possibilities for indirect searches of new phenomena through high-precision tests of the SM. In addition, by collecting tens of ab$^{-1}$ integrated luminosity in the range of center-of-mass energies $\\sqrt{s}$~=90--350~GeV, the FCC-ee also offers unique physics opportunities for precise measurements of QCD phenomena and of photon-photon collisions through, literally, billions of hadronic final states as well as unprecedented large fluxes of quasireal $\\gamma$'s radiated from the $\\rm e^+e^-$ beams. We succinctly summarize the FCC-ee perspectives for high-precision extractions of the QCD coupling, for detailed analyses of parton radiation and fragmentation, and for SM and BSM studies through $\\gamma\\gamma$ collisions.

  9. Towards an improved understanding of eta --> gamma^* gamma^*

    CERN Document Server

    Xiao, C W; Hanhart, C; Kubis, B; Meißner, U -G; Wirzba, A

    2015-01-01

    We argue that high-quality data on the reaction $e^+e^-\\to \\pi^+\\pi^-\\eta$ will allow one to determine the double off-shell form factor $\\eta \\to \\gamma^*\\gamma^*$ in a model-independent way with controlled accuracy. This is an important step towards a reliable evaluation of the hadronic light-by-light scattering contribution to the anomalous magnetic moment of the muon. When analyzing the existing data for $e^+e^- \\to \\pi^+\\pi^-\\eta$ in the range of total energies $1\\text{GeV}^2gamma^*\\gamma^*}(Q_1^2,Q_2^2)$ is consistent with the commonly employed factorization ansatz at least for $Q_1^2<1\\text{GeV}^2$, if the effect of the $a_2$ meson is taken into account. However, better data are needed to draw firm conclusions.

  10. Realization of a gamma multiplicity filter and gamma multiplicity measurements

    International Nuclear Information System (INIS)

    A gamma multiplicity filter for the study of reaction mechanism has been realised. It's composed of six NaI(Tl) counters. The flexibility of the geometry allows many configurations. This set up has been tested with gamma radioactive sources and with the 252Cf source to resolve problems of gamma-efficiency of the NaI(Tl) counters and the contamination of neutrons in these detectors. A logical electronic unit (Encodeur) has been constructed and the around electronic has been developped. This gamma multiplicity filter has been coupled with a detector of high resolution Ge(Li), and used in two reactions: 12C + 55Mn at E(12C) = 54 MeV; α + 63Cu at E(α) = 52 MeV. The dominant process is the fusion-evaporation. The compound nucleus 67Ga, is formed at the same excitation energy. The values of multiplicities Msub(γ) have been extracted using a program based on the formalism of W.J. Ockels. The fractionalization of the angular momentum is well observed for some residual nuclei (63Zn, 64Zn, 65Zn), and for each residual nucleus, the average gamma multiplicity is lower with projectile α than that with projectile 12C. For the most strongly output channel p2n, an entry point for the 64Zn has been determined in the reactions. All these observations are in good agreement with those published, in the same region (f-p shell) of nuclei. This set up can be coupled with different central detector as, ''X'', neutrons charged particles detectors, and will be used with the new machine SARA to make a systematic study of transfer of angular momentum to the fragments at 30 MeV/A

  11. Higgs boson decays into {\\gamma}{\\gamma} and Z{\\gamma} in the MSSM and BLSSM

    CERN Document Server

    Hammad, A; Moretti, S

    2015-01-01

    We calculate Higgs decay rates into {\\gamma}{\\gamma} and Z{\\gamma} in the Minimal Supersymmetric Standard Model (MSSM) and (B-L) Supersymmetric Standard Model (BLSSM) by allowing for contributions from light staus and charginos. We show that sizable departures are possible from the SM predictions for the 125 GeV state and that they are testable during run 2 at the Large Hadron Collider. Furthermore, we illustrate how a second light scalar Higgs signal in either or both these decay modes can be accessed at the CERN machine rather promptly within the BLSSM, a possibility instead precluded to the MSSM owing to the much larger mass of its heavy scalar state.

  12. On Some Properties of Gamma Matrices

    Science.gov (United States)

    Dumais, Jean-Francois

    1977-01-01

    Discusses the problem of the order, reducibility, and equivalence of systems of Dirac gamma matrices. Gives a simple systematic method for finding the matrices connecting different systems of 4 x 4 gamma matrices. (MLH)

  13. Gamma-Ray Interactions for Reachback Analysts

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, Steven Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-02

    This presentation is a part of the DHS LSS spectroscopy training course and presents an overview of the following concepts: identification and measurement of gamma rays; use of gamma counts and energies in research.

  14. Search for Anomalous $ZZ\\gamma$ and $Z\\gamma\\gamma$ couplings in the process $e^{+}e^{-} \\to Z\\gamma$ at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brigljevic, V; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; Durán, I; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Extermann, Pierre; Fabre, M; Faccini, R; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lassila-Perini, K M; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marchesini, P A; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Molnár, P; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Robohm, A; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Rubio, Juan Antonio; Ruggiero, G; Ruschmeier, D; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Sarakinos, M E; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Sciarrino, D; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, M; Wang, X L; Wang, Z M; Weber, A; Weber, M; Wienemann, P; Wilkens, H; Wu, S X; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Ye, J B; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhu, G Y; Zhu, R Y; Zichichi, A; Zilizi, G; Zöller, M

    2000-01-01

    We search for anomalous trilinear gauge couplings in the ${\\rm ZZ}\\gamma$ and ${\\rm Z}\\gamma\\gamma$ vertices using data collected with the L3 detectorat LEP at a centre--of--mass energy $\\sqrt{s}=189$ GeV. No evidence is found and limits on these couplings and on new physics scales are derived from the analysis of the process ${\\rm e}^{+}{\\rm e}^{-} \\rightarrow {\\rm Z} \\gamma$.

  15. A New Search for tau -> mu gamma and tau -> e gamma Decays at Belle

    CERN Document Server

    Abe, K; Aihara, H; Anipko, D; Aoki, K; Arakawa, T; Arinstein, K; Asano, Y; Aso, T; Aulchenko, V M; Aushev, T; Aziz, T; Bahinipati, S; Bakich, A M; Balagura, V; Ban, Y; Banerjee, S; Barberio, E; Barbero, M; Bay, A; Bedny, I; Belous, K S; Bitenc, U; Bizjak, I; Blyth, S; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chang, P; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chistov, R; Choi, J H; Choi, S K; Choi, Y; Choi, Y K; Chuvikov, A; Cole, S; Dalseno, J; Danilov, M; Dash, M; Dowd, R; Dragic, J; Drutskoy, A; Eidelman, S; Enari, Y; Epifanov, D A; Fratina, S; Fujii, H; Fujikawa, M; Gabyshev, N; Garmash, A; Gershon, T; Go, A; Gokhroo, G; Goldenzweig, P; Golob, B; Gorisek, A; Grosse-Perdekamp, M; Guler, H; Ha, H; Haba, J; Hara, K; Hara, T; Hasegawa, Y; Hastings, N C; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Higuchi, T; Hinz, L; Hokuue, T; Hoshi, Y; Hoshina, K; Hou, S; Hou, W S; Hsiung, Y B; Igarashi, Y; Iijima, T; Ikado, K; Imoto, A; Inami, K; Ishikawa, A; Ishino, H; Itoh, K; Itoh, R; Iwabuchi, M; Iwasaki, M; Iwasaki, Y; Jacoby, C; Jones, M; Kakuno, H; Kang, J H; Kang, J S; Kapusta, P; Kataoka, S U; Katayama, N; Kawai, H; Kawasaki, T; Khan, H R; Kibayashi, A; Kichimi, H; Kikuchi, N; Kim, H J; Kim, H O; Kim, J H; Kim, S K; Kim, T H; Kim, Y J; Kinoshita, K; Kishimoto, N; Korpar, S; Kozakai, Y; Krizan, P; Krokovnyi, P P; Kubota, T; Kulasiri, R; Kumar, R; Kuo, C C; Kurihara, E; Kusaka, A; Kuzmin, A; Kwon, Y J; Lange, J S; Leder, G; Lee, J; Lee, S E; Lee, Y J; Lesiak, T; Li, J; Limosani, A; Lin, C Y; Lin, S W; Liu, Y; Liventsev, D; MacNaughton, J; Majumder, G; Mandl, F; Marlow, D; Matsumoto, T; Matyja, A; McOnie, S; Medvedeva, T; Mikami, Y; Mitaroff, W A; Miyabayashi, K; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Mohapatra, D; Moloney, G R; Mori, T; Müller, J; Murakami, A; Nagamine, T; Nagasaka, Y; Nakagawa, T; Nakahama, Y; Nakamura, I; Nakano, E; Nakao, M; Nakazawa, H; Natkaniec, Z; Neichi, K; Nishida, S; Nishimura, K; Nitoh, O; Noguchi, S; Nozaki, T; Ogawa, A; Ogawa, S; Ohshima, T; Okabe, T; Okuno, S; Olsen, S L; Ono, S; Ostrowicz, W; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Park, H; Park, K S; Parslow, N; Peak, L S; Pernicka, M; Pestotnik, R; Peters, M; Piilonen, L E; Poluektov, A; Ronga, F J; Root, N; Rorie, J; Rózanska, M; Sahoo, H; Saitoh, S; Sakai, Y; Sakamoto, H; Sakaue, H; Sarangi, T R; Sato, N; Satoyama, N; Sayeed, K; Schietinger, T; Schneider, O; Schonmeier, P; Schümann, J; Schwanda, C; Schwartz, A J; Seidl, R; Seki, T; Senyo, K; Sevior, M E; Shapkin, M; Shen, Y T; Shibuya, H; Shwartz, B; Sidorov, V; Singh, J B; Sokolov, A; Somov, A; Soni, N; Stamen, R; Stanic, S; Staric, M; Stöck, H; Sugiyama, A; Sumisawa, K; Sumiyoshi, T; Suzuki, S; Suzuki, S Y; Tajima, O; Takada, N; Takasaki, F; Tamai, K; Tamura, N; Tanabe, K; Tanaka, M; Taylor, G N; Teramoto, Y; Tian, X C; Tikhomirov, I; Trabelsi, K; Tsai, Y T; Tse, Y F; Tsuboyama, T; Tsukamoto, T; Uchida, K; Uchida, Y; Uehara, S; Uglov, T; Ueno, K; Unno, Y; Uno, S; Urquijo, P; Ushiroda, Y; Usov, Yu; Varner, G; Varvell, K E; Villa, S; Wang, C C; Wang, C H; Wang, M Z; Watanabe, M; Watanabe, Y; Wicht, J; Widhalm, L; Wiechczynski, J; Won, E; Wu, C H; Xie, Q L; Yabsley, B D; Yamaguchi, A; Yamamoto, H; Yamamoto, S; Yamashita, Y; Yamauchi, M; Heyoung Yang; Yoshino, S; Yuan, Y; Yusa, Y; Zang, S L; Zhang, C C; Zhang, J; Zhang, L M; Zhang, Z P; Zhilich, V; Ziegler, T; Zupanc, A; Zürcher, D

    2006-01-01

    We update our search for the lepton flavor violating tau -> mu gamma and tau -> e gamma decays based on 535/fb of data accumulated at the Belle experiment. No signal is found and we set preliminary 90% confidence level upper limits: B(tau -> mu gamma) e gamma) < 1.2x 10^-7.

  16. Gamma and X 93 spectrometry

    International Nuclear Information System (INIS)

    The Meetings of Gamma and X 93 Spectrometry were held on 12-14 October 1993. The symposium was organized into six sessions: Instrumentation development, Nuclear matter measurement, Method and calibration, Medical applications, Environment survey (radioactive traces measurement), other applications (spent fuels analysis, various techniques). Separate abstracts were prepared for all the papers in this volume. (TEC)

  17. Gamma scanner conceptual design report

    International Nuclear Information System (INIS)

    The Fuels and Materials Examination Facility (FMEF) will include several stations for the nondestructive examination of irradiated fuels. One of these stations will be the gamma scanner which will be employed to detect gamma radiation from the irradiated fuel pins. The conceptual design of the gamma scan station is described. The gamma scanner will use a Standard Exam Stage (SES) as a positioner and transport mechanism for the fuel pins which it will obtain from a magazine. A pin guide mechanism mounted on the face of the collimator will assure that the fuel pins remain in front of the collimator during scanning. The collimator has remotely adjustable tungsten slits and can be manually rotated to align the slit at various angles. A shielded detector cart located in the operating corridor holds an intrinsic germanium detector and associated sodium-iodide anticoincidence detector. The electronics associated with the counting system consist of standard NIM modules to process the detector signals and a stand-alone multichannel analyzer (MCA) for counting data accumulation. Data from the MCA are bussed to the station computer for analysis and storage on magnetic tape. The station computer controls the collimator, the MCA, a source positioner and the SES through CAMAC-based interface hardware. Most of the electronic hardware is commercially available but some interfaces will require development. Conceptual drawings are included for mechanical hardware that must be designed and fabricated

  18. Novae in gamma-rays

    CERN Document Server

    Hernanz, M

    2013-01-01

    Classical novae produce radioactive nuclei which are emitters of gamma-rays in the MeV range. Some examples are the lines at 478 and 1275 keV (from 7Be and 22Na) and the positron-electron annihilation emission (511 keV line and a continuum below this energy, with a cut-off at 20-30 keV). The analysis of gamma-ray spectra and light curves is a potential unique and powerful tool both to trace the corresponding isotopes and to give insights on the properties of the expanding envelope determining its transparency. Another possible origin of gamma-rays is the acceleration of particles up to very high energies, so that either neutral pions or inverse Compton processes produce gamma-rays of energies larger than 100 MeV. MeV photons during nova explosions have not been detected yet, although several attempts have been made in the last decades; on the other hand, GeV photons from novae have been detected in some particular novae, in symbiotic binaries, where the companion is a red giant with a wind, instead of a main ...

  19. Gamma ray slush hydrogen monitor

    Science.gov (United States)

    Singh, Jag J.; Shen, Chih-Peng; Sprinkle, Danny R.

    1992-01-01

    Mass attenuation for 109Cd radiation have been measured in mixtures of phases and in single phases of five chemical compounds. As anticipated, the mass attenuation coefficients are independent of the phases of the test chemicals. It is recommended that a slush hydrogen monitoring system based on low energy gamma ray attenuation be developed for utilization aboard the NASP.

  20. Short duration gamma ray bursts

    Indian Academy of Sciences (India)

    Patrick Das Gupta

    2004-10-01

    After a short review of gamma ray bursts (GRBs), we discuss the physical implications of strong statistical correlations seen among some of the parameters of short duration bursts (90 < 2 s). Finally, we conclude with a brief sketch of a new unified model for long and short GRBs.

  1. Gamma spectrometry of infinite 4Π geometry

    International Nuclear Information System (INIS)

    Owing to the weak absorption og gamma radiation by matter, gamma-ray spectrometry may be applied to samples of great volume. A very interesting case is that of the gamma-ray spectrometry applied with 4Π geometry around the detector on a sample assumed to be of infinite extension. The determination of suitable efficiencies allows this method to be quantitative. (author)

  2. The Processing Software of Gamma Spetrum

    Institute of Scientific and Technical Information of China (English)

    SHAO; Jie-wen; BAI; Lei; CHENG; Yi-mei; HE; Li-xia

    2012-01-01

    <正>ORTEC’s MAESTRO\\GammaVision and Canberra’s Genie2000 are two major softwares for operating the front spectrometer in gamma measurement. But the functions are limited to gamma acquisition & analysis. In routine analysis and the analytical method of some NDA special equipment, users usually require the use of other more unique and complex function.

  3. Gamma and Related Functions Generalized for Sequences

    Science.gov (United States)

    Ollerton, R. L.

    2008-01-01

    Given a sequence g[subscript k] greater than 0, the "g-factorial" product [big product][superscript k] [subscript i=1] g[subscript i] is extended from integer k to real x by generalizing properties of the gamma function [Gamma](x). The Euler-Mascheroni constant [gamma] and the beta and zeta functions are also generalized. Specific examples include…

  4. Gamma-Ray Interactions for Reachback Analysts

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, Steven Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-02

    This presentation is a part of the DHS LSS spectroscopy training course and presents an overview of the following concepts: identification and measurement of gamma rays; use of gamma counts and energies in research. Understanding the basic physics of how gamma rays interact with matter can clarify how certain features in a spectrum were produced.

  5. Branching Fraction Measurements of B+ -> rho+ gamma, B0 -> rho0 gamma, and B0 -> omega gamma

    CERN Document Server

    Aubert, B; Abrams, G S; Adye, T; Ahmed, S; Alam, M S; Albert, J; Aleksan, R; Allen, M T; Allison, J; Altenburg, D D; Andreotti, M; Angelini, C; Anulli, F; Arnaud, N; Asgeirsson, D J; Aston, D; Azzolini, V; Baak, M A; Back, J J; Baldini-Ferroli, R; Band, H R; Banerjee, Sw; Bard, D J; Barlow, N R; Barlow, R J; Barrett, M; Bartoldus, R; Batignani, G; Battaglia, M; Bauer, J M; Bechtle, P; Beck, T W; Behera, P K; Bellini, F; Ben-Haim, E; Benelli, G; Berger, N; Bernard, D; Berryhill, J W; Bettarini, S; Bettoni, D; Bevan, A J; Bhuyan, B; Bianchi, F; Biasini, M; Biesiada, J; Blanc, F; Blaylock, G; Blinov, V E; Bloom, P C; Blount, N L; Bomben, M; Bondioli, M; Bonneaud, G R; Bosisio, L; Boutigny, D; Boyd, J T; Bozzi, C; Brandt, T; Brau, J E; Briand, H; Brown, D N; Bruinsma, M; Brunet, S; Buchanan, C; Bugg, W; Bukin, A D; Bula, R; Burchat, P R; Burke, J P; Button-Shafer, J; Buzzo, A; Bóna, M; Cahn, R N; Calabrese, R; Calcaterra, A; Calderini, G; Campagnari, C; Carpinelli, M; Cartaro, C; Castelli, G; Cavallo, N; Cavoto, G; Cenci, R; Chai, X; Chaisanguanthum, K S; Chao, M; Charles, M J; Chauveau, J; Chavez, C A; Chen, A; Chen, C; Chen, E; Chen, J C; Chen, S; Chen, X; Chen, X R; Cheng, C H; Chia, Y M; Cibinetto, G; Clark, P J; Claus, R; Cochran, J; Coleman, J P; Contri, R; Convery, M R; Corwin, L A; Cossutti, F; Cottingham, W N; Covarelli, R; Cowan, G; Cowan, R; Crawley, H B; Cremaldi, L; Cunha, A; Curry, S; Côté, D; D'Orazio, A; Dahmes, B; Dallapiccola, C; Dasu, S; Dauncey, P D; David, P; Davier, M; Davis, C L; De Nardo, Gallieno; De Sangro, R; Del Amo-Sánchez, P; Del Buono, L; Del Re, D; Della Ricca, G; Denig, A G; Di Lodovico, F; Di Marco, E; Dingfelder, J C; Dong, L; Dorfan, J; Druzhinin, V P; Dubitzky, R S; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W; Dvoretskii, A; Ebert, M; Eckhart, E A; Eckmann, R; Edgar, C L; Edwards, A J; Eigen, G; Eisner, A M; Elmer, P; Emery, S; Ernst, J A; Escalier, M; Eschenburg, V; Eschrich, I; Eyges, V; Fabozzi, F; Faccini, R; Fang, F; Feltresi, E; Ferrarotto, F; Ferroni, F; Field, R C; Finocchiaro, G; Flacco, C J; Flack, R L; Flächer, H U; Flood, K T; Ford, W T; Forster, I J; Forti, F; Foulkes, S D; Franek, B; Frey, R; Fritsch, M; Fry, J R; Fulsom, B G; Gabathuler, E; Gaidot, A; Gallo, F; Gamba, D; Gamet, R; Gan, K K; Ganzhur, S F; Gary, J W; Gaspero, M; Gatto, C; Gaz, A; George, K A; Giorgi, M A; Gladney, L; Glanzman, T; Godang, R; Golubev, V B; Gowdy, S J; Gradl, W; Graham, M T; Graugès-Pous, E; Grenier, P; Gritsan, A V; Grosdidier, G; Groysman, Y; Haire, M; Halyo, V; Hamano, K; Hamel de Monchenault, G; Hamon, O; Harrison, P F; Harrison, T J; Hart, A J; Hartfiel, B L; Hast, C; Hauke, A; Hawkes, C M; Hearty, C; Held, T; Hertzbach, S S; Heusch, C A; Hill, E J; Hirschauer, J F; Hitlin, D G; Hollar, J J; Hong, T M; Honscheid, K; Hopkins, D A; Hrynóva, T; Hufnagel, D; Hulsbergen, W D; Hutchcroft, D E; Höcker, A; Igonkina, O; Innes, W R; Izen, J M; Jackson, P D; Jackson, P S; Jacobsen, R G; Jain, V; Jasper, H; Jawahery, A; Jessop, C P; Kadyk, J A; Kagan, H; Karyotakis, Yu; Kass, R; Kelsey, M H; Kerth, L T; Khan, A; Kim, H; Kim, P; Kirkby, D; Klose, V; Knecht, N S; Koch, H; Koeneke, K; Kolb, J A; Kolomensky, Yu G; Kovalskyi, D; Kowalewski, R V; Kozanecki, W; Kreisel, A; Krishnamurthy, M; Kroeger, R; Kroseberg, J; Kukartsev, G; Kutter, P E; Kyberd, P; La Vaissière, C de; Lacker, H M; Lae, C K; Lafferty, G D; Lanceri, L; Lang, M I; Lange, D J; Lankford, A J; Latham, T E; Latour, E; Lau, Y P; Lazzaro, A; Le Diberder, F R; Lees, J P; Legendre, M; Leith, D W G S; Lepeltier, V; Leruste, P; Lewandowski, B; Li Gioi, L; Li, S; Li, X; Lista, L; Liu, F; Liu, H; Lo Vetere, M; LoSecco, J M; Lockman, W S; Lombardo, V; Long, O; Lopes-Pegna, D; Lopez-March, N; Lou, X C; Lu, M; Luitz, S; Lund, P; Luppi, E; Lusiani, A; Lutz, A M; Lynch, G; Lynch, H L; Lü, C; Lüth, V; MacFarlane, D B; Macri, M M; Mader, W F; Majewski, S A; Malcles, J; Mallik, U; Mancinelli, G; Mandelkern, M A; Marchiori, G; Margoni, M; Marks, J; Marsiske, H; Martin, E C; Martínez-Vidal, F; Mattison, T S; Mazur, M A; Mazzoni, M A; McKenna, J A; McMahon, T R; Mclachlin, S E; Meadows, B T; Mellado, B; Menges, W; Merkel, J; Messner, R; Meyer, N T; Meyer, W T; Mir, L M; Mishra, K; Mohanty, G B; Monge, M R; Monorchio, D; Moore, T B; Morandin, M; Morganti, M; Morganti, S; Morii, M; Morris, J P; Muheim, F; Müller, D R; Nagel, M; Narsky, I; Nash, J A; Nauenberg, U; Neal, H; Negrini, M; Neri, N; Nicholson, H; Nikolich, M B; Nogowski, R; Nugent, I M; O'Grady, C P; Ocariz, J; Ofte, I; Olaiya, E O; Olivas, A; Olsen, J; Onuchin, A P; Orimoto, T J; Oyanguren, A; Ozcan, V E; Paar, H P; Pacetti, S; Palano, A; Palombo, F; Pan, B; Pan, Y; Panduro-Vazquez, W; Paoloni, E; Paolucci, P; Pappagallo, M; Park, W; Passaggio, S; Patel, P M; Patrignani, C; Patteri, P; Payne, D J; Pelizaeus, M; Pelliccioni, M; Perazzo, A; Perl, M

    2006-01-01

    We present a study of the decays B+ -> rho+ gamma, B0 -> rho0 gamma, and B0 -> omega gamma. The analysis is based on data containing 347 million BBbar events recorded with the BaBar detector at the PEP-II asymmetric B factory. We measure the branching fractions BR(B+ -> rho+ gamma) = (1.10 +0.37/-0.33 +/- 0.09) x 10-6 and BR(B0 -> rho0 gamma) = (0.79 +0.22/-0.20 +/- 0.06) x 10-6, and set a 90% C.L. upper limit BR(B0 -> omega gamma) rho/omega gamma) = (1.25 +0.25/-0.24 +/- 0.09) x 10-6, from which we determine |Vtd/Vts| = 0.200 +0.021/-0.020 +/- 0.015, where the first uncertainty is experimental and the second is theoretical.

  6. Measurement of the gamma gamma* -> pi0 transition form factor

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2009-06-02

    We study the reaction e{sup +}e{sup -} {yields} e{sup +}e{sup -}{pi}{sup 0} in the single tag mode and measure the differential cross section d{sigma}/dQ{sup 2} and the {gamma}{gamma}* {yields} {pi}{sup 0} transition form factor in the mometum transfer range from 4 to 40 GeV{sup 2}. At Q{sup 2} > 10 GeV{sup 2} the measured form factor exceeds the asymptotic limit predicted by perturbative QCD. The analysis is based on 442 fb{sup -1} of integrated luminosity collected at PEP-II with the BABAR detector at e{sup +}e{sup -} center-of-mass energies near 10.6 GeV.

  7. Transitional gamma strength in Cd isotopes

    OpenAIRE

    Larsen, André; Ruud, I. E.; Burger, Arnold; Goriely, Stéphane; Guttormsen, Magne; Görgen, Andreas; Hagen, W. T.; Harissopulos, Sotirios; Nyhus, Hilde Therese; Renstrom, T.; Schiller, Andreas; Siem, Sunniva; Tveten, G. M.; Voinov, A.; Wiedeking, M.

    2013-01-01

    The level densities and $\\gamma$-ray strength functions of $^{105,106,111,112}$Cd have been extracted from particle-$\\gamma$ coincidence data using the Oslo method. The level densities are in very good agreement with known levels at low excitation energy. The $\\gamma$-ray strength functions display no strong enhancement for low $\\gamma$ energies. However, more low-energy strength is apparent for $^{105,106}$Cd than for $^{111,112}$Cd. For $\\gamma$ energies above $\\approx$ 4 MeV, there is evid...

  8. Urban gamma spectrometry. Report 2

    Energy Technology Data Exchange (ETDEWEB)

    Aage, H.K. (Technical Univ. of Denmark, Kgs. Lyngby (Denmark)); Kuukankorpi, S.; Moring, M.; Smolander, P.; Toivonen, H. (Radiation and Nuclear Safety Authority, Helsinki (Finland))

    2009-06-15

    Urban gamma spectrometry has been given only minor attention with the focus being on rural gamma spectrometry. However, in recent years the Nordic emergency management authorities have turned focus towards border control and lost or stolen sources. Gamma spectra measured in urban areas are characterized by a wide variety of spectrum shapes and very fast changes in environmental background. In 2004 a Danish CGS (Carborne Gamma Spectrometry) survey took place in Copenhagen. It was found that gamma spectrometry in urban areas is far more complicated to interpret than had previously been thought and a new method 'Fitting with Spectral Components', FSC, based on NASVD, was tested with some success. In Finland, a database 'LINSSI' has been developed for spectral data management. In CGS search mode a 'peak hypothesis test' is applied to the measured spectra. This system was tested during the Helsinki 2005 Athletics World Championship and it provides fast and reliable automated alarms for intermediate and high level signals. In Sweden mobile detector systems are used for border controls and problems are encountered when making measurement in harbour, container areas. The methods for handling data and for interpretation of urban gamma spectrometry measurements were compared and tested on the same data sets from Copenhagen and Helsinki. Software tools were developed for converting data between the Finnish LINSSI database and the binary file formats used in Denmark and Sweden. The Processing methods used at DTU and STUK have different goals. The ASSS and FSC methods are designed to optimize the overall detection capability of the system, while sacrificing speed, usability and to a certain level robustness. These methods cannot always be used for real time analysis. The Peak Significance method is designed to give robust alarms in real time, while sacrificing some of the detection capability. Thus these methods are not interchangeable, but rather

  9. Gamma-ray emission from thunderstorm discharges

    International Nuclear Information System (INIS)

    Fine features of gamma-ray radiation registered during a thunderstorm at Tien-Shan Mountain Cosmic Ray Station are presented. Long duration (100-600 ms) gamma-ray bursts are found. They are for the first time identified with atmospheric discharges (lighting). Gamma-ray emission lasts all the time of the discharge and is extremely non-uniform consisting of numerous flashes. Its peak intensity in the flashes exceeds the gamma-ray background up to two orders of magnitude. Exclusively strong altitude dependence of gamma radiation is found. The observation of gamma radiation at the height 4-8 km could serve as a new important method of atmospheric discharge processes investigation. - Highlights: → Gamma-radiation bursts always accompany the electric discharges in atmosphere. → The gamma burst fill up the time of an atmospheric discharge completely. → The higher is the discharge electric field change - the higher is gamma intensity. → The temporal distribution of gamma intensity during the burst is non-uniform. → The altitude dependence of the burst gamma intensity is dramatic.

  10. Status of the GAMMA-400 Project

    CERN Document Server

    Galper, A M; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Boezio, M; Bonvicini, V; Boyarchuk, K A; Gusakov, Yu V; Farber, M O; Fradkin, M I; Kachanov, V A; Kaplin, V A; Kheymits, M D; Leonov, A A; Longo, F; Maestro, P; Marrocchesi, P; Mazets, E P; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I; Naumov, P Yu; Papini, P; Picozza, P; Rodin, V G; Runtso, M F; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Topchiev, N P; Vacchi, A; Vannuccini, E; Yurkin, Yu T; Zampa, N; Zverev, V G

    2012-01-01

    The preliminary design of the new space gamma-ray telescope GAMMA-400 for the energy range 100 MeV - 3 TeV is presented. The angular resolution of the instrument, 1-2{\\deg} at E{\\gamma} ~100 MeV and ~0.01^{\\circ} at E{\\gamma} > 100 GeV, its energy resolution ~1% at E{\\gamma} > 100 GeV, and the proton rejection factor ~10E6 are optimized to address a broad range of science topics, such as search for signatures of dark matter, studies of Galactic and extragalactic gamma-ray sources, Galactic and extragalactic diffuse emission, gamma-ray bursts, as well as high-precision measurements of spectra of cosmic-ray electrons, positrons, and nuclei.

  11. Measurement of the $ \\mathrm{ Z } \\gamma \\rightarrow \

    Energy Technology Data Exchange (ETDEWEB)

    Khachatryan, Vardan; et al.

    2016-02-23

    A measurement of the Z gamma to nu nu-bar gamma production cross section in pp collisions at sqrt(s) = 8 TeV is presented, using data corresponding to an integrated luminosity of 19.6 inverse-femtobarns collected with the CMS detector at the LHC. This measurement is based on the observation of events with large missing energy and with a single photon with transverse momentum above 145 GeV and absolute pseudorapidity in the range |eta| < 1.44. The measured Z gamma to nu nu-bar gamma production cross section, 52.7 +/- 2.1(stat) +/- 6.4 (syst) +/- 1.4 (lumi) fb, agrees well with the standard model prediction of 50.0+2.4-2.2 fb. A study of the photon transverse momentum spectrum yields the most stringent limits to date on the anomalous Z-Z-gamma and Z-gamma-gamma trilinear gauge boson couplings.

  12. T cell receptor gamma/delta chain diversity

    OpenAIRE

    1988-01-01

    The TCR-gamma and -delta chains of six murine hybridomas were compared by one-dimensional SDS-PAGE and two-dimensional NEPHGE/SDS-PAGE analysis. This allowed the identification of three distinct gamma chains (gamma a, gamma b, and gamma c) and three distinct delta chains (delta a, delta b, and delta c). Four gamma/delta chain combinations (gamma a delta a, gamma b delta b, gamma b delta c, and gamma c delta a) were observed. These results indicate that multiple forms of the delta chain are ex...

  13. CD-ROM和CD-ROM XA

    Institute of Scientific and Technical Information of China (English)

    申江

    1995-01-01

    @@ 供计算机作大容量存储器用的激光唱片称激光唱片只读存储器(Compact Disc Read Only Memory),简称CD-ROM,其机械和光学性能大多与普通CD相同,不同之处仅在于数据格式.

  14. Bioengineering factor Xa to treat bleeding.

    Science.gov (United States)

    Camire, Rodney M

    2016-05-01

    There is a clinical need to develop safe and rapid therapeutic strategies to control bleeding arising from a host of emergent situations. Over the past several years our laboratory has developed novel zymogen-like FXa variants and tested their safety and efficacy using hemophilia as a model system. The variants have a spectrum of properties resulting from an amino acid change at the N-terminus of the heavy chain that alters a critical conformational change. These properties, which include resistance to plasma protease inhibitors, low activity in the absence of FVa, and rescue of low activity upon incorporation in prothrombinase, yield remarkably effective pro-hemostatic agents. The FVa-dependent restoration of activity is a key aspect to their efficacy and also contributes to localizing the variants to the site of vascular injury. While pre-clinical data support their use in the setting of hemophilia, they have the potential to act as rapid pro-hemostatic agents for the treatment of a range of bleeding conditions. This review will discuss the biochemical properties of these FXa zymogen-like variants and their in vivo characterization. PMID:27207419

  15. LEPS backward gamma detector reassembled

    International Nuclear Information System (INIS)

    A new electro-magnetic (EM) calorimeter complex FOREST covering a solid angle of about 4π sr is under construction. It consists of three calorimeters: the EPS forward one made up of pure CsI crystals, the middle one of lead scintillating fiber (Lead/SciFi) modules, and the backward one of lead glass Cerenkov counters. We have reassembled the middle calorimeter, comprised of 252 Lead/SciFi modules, which used to be the LEPS Backward Gamma detector system utilized in a LEPS experiment at SPring-8. A performance test for the gamma detector system has been made with a photon beam in the GeV γ experimental hall. The π0 peak is clearly observed in the γγ invariant mass distribution. (author)

  16. Airborne gamma ray spectrometer surveying

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency (IAEA) in its role as collector and disseminator of information on nuclear techniques has long had an interest in gamma ray spectrometer methods and has published a number of Technical Reports on various aspects of the subject. At an Advisory Group Meeting held in Vienna in November 1986 to review appropriate activities the IAEA could take following the Chernobyl accident, it was recommended that preparation begin on a new Technical Report on airborne gamma ray spectrometer surveying, taking into account the use of the technique for environmental monitoring as well as for nuclear emergency response requirements. Shortly thereafter the IAEA became the lead organization in the Radioelement Geochemical Mapping section of the International Geological Correlation Programme/United Nations Educational, Scientific and Cultural Organization (UNESCO) Project on International Geochemical Mapping. These two factors led to the preparation of the present Technical Report. 18 figs, 4 tabs

  17. Gamma sterilization of perfumed talcs

    International Nuclear Information System (INIS)

    Formula of talcs powders manufactured in cosmetic industry often includes starch and therefore they cannot be sterilized by ordinary dry heat processes. Gamma ray are most convenient, but one might expect a resulting adulteration of perfume, if present in the item. Contrarely, it was found that no modification seemed to occur, in the scent of the sterilized product. Increase of stability, after long storage, was even observed

  18. Monomial Gamma Monte Carlo Sampling

    OpenAIRE

    Zhang, Yizhe; Wang, Xiangyu; Chen, Changyou; Fan, Kai; Carin, Lawrence

    2016-01-01

    We unify slice sampling and Hamiltonian Monte Carlo (HMC) sampling by demonstrating their connection under the canonical transformation from Hamiltonian mechanics. This insight enables us to extend HMC and slice sampling to a broader family of samplers, called monomial Gamma samplers (MGS). We analyze theoretically the mixing performance of such samplers by proving that the MGS draws samples from a target distribution with zero-autocorrelation, in the limit of a single parameter. This propert...

  19. Supernovae and Gamma Ray Bursts

    Directory of Open Access Journals (Sweden)

    M. Della Valle

    2007-01-01

    Full Text Available Se revisa el estatus observacional de la conexi on Supernova (SN/Estallido de Rayos-Gamma (GRB. Recientes (y no tan recientes observaciones de GRBs largos sugieren que una fracci on signi cativa de ellos (pero no todos est an asociados con supernovas brillantes del tipo Ib/c. Estimaciones actuales de las tasas de producci on de GRBs y SNs dan una raz on para GRB/SNe-Ibc en el rango 0:4%

  20. Neutrinos from Gamma Ray Bursts

    CERN Document Server

    Mannheim, K

    2000-01-01

    The observed fluxes of cosmic rays and gamma rays are used to infer the maximum allowed high-energy neutrino flux allowed for Gamma Ray Bursts (GRBs), following Mannheim, Protheroe, and Rachen (2000). It is shown that if GRBs produce the ultrahigh-energy cosmic rays, they should contribute (a) at least 10% of the extragalactic gamma ray background between 3 MeV and 30 GeV, contrary to their observed energy flux which is only a minute fraction of this flux, and (b) a cumulative neutrino flux a factor of 20 below the AMANDA (Neutrino 2000) limit on isotropic neutrinos. This could have two implications, either GRBs do not produce the ultrahigh energy cosmic rays or that the GRBs are strongly beamed and emit most of their power at energies well above 100 GeV implausibly increasing the energy requirements, but consistent with the marginal detections of a few low-redshift GRBs by MILAGRITO, HEGRA-AIROBICC, and the Tibet-Array. All crucial measurements to test the models will be available in the next few years. Thes...

  1. Evidence for $\\eta_{c} \\rightarrow \\gamma\\gamma$ and Measurement of $J/\\psi\\rightarrow 3\\gamma$

    CERN Document Server

    Ablikim, M; Ambrose, D J; An, F F; An, Q; An, Z H; Bai, J Z; Ban, Y; Becker, J; Bertani, M; Bian, J M; Boger, E; Bondarenko, O; Boyko, I; Briere, R A; Bytev, V; Cai, X; Cakir, O; Calcaterra, A; Cao, G F; Cetin, S A; Chang, J F; Chelkov, G; Chen, G; Chen, H S; Chen, J C; Chen, M L; Chen, S J; Chen, Y B; Cheng, H P; Chu, Y P; Cronin-Hennessy, D; Dai, H L; Dai, J P; Dedovich, D; Deng, Z Y; Denig, A; Denysenko, I; Destefanis, M; Ding, W M; Ding, Y; Dong, L Y; Dong, M Y; Du, S X; Fang, J; Fang, S S; Fava, L; Feldbauer, F; Feng, C Q; Ferroli, R B; Fu, C D; Fu, J L; Gao, Y; Geng, C; Goetzen, K; Gong, W X; Gradl, W; Greco, M; Gu, M H; Gu, Y T; Guan, Y H; Guo, A Q; Guo, L B; Guo, Y P; Han, Y L; Harris, F A; He, K L; He, M; He, Z Y; Held, T; Heng, Y K; Hou, Z L; Hu, H M; Hu, J F; Hu, T; Huang, G M; Huang, J S; Huang, X T; Huang, Y P; Hussain, T; Ji, C S; Ji, Q; Ji, X B; Ji, X L; Jiang, L L; Jiang, X S; Jiao, J B; Jiao, Z; Jin, D P; Jin, S; Jing, F F; Kalantar-Nayestanaki, N; Kavatsyuk, M; Kuehn, W; Lai, W; Lange, J S; Li, C H; Li, Cheng; Li, Cui; Li, D M; Li, F; Li, G; Li, H B; Li, J C; Li, K; Li, Lei; Li, Q J; Li, S L; Li, W D; Li, W G; Li, X L; Li, X N; Li, X Q; Li, X R; Li, Z B; Liang, H; Liang, Y F; Liang, Y T; Liao, G R; Liao, X T; Liu, B J; Liu, C L; Liu, C X; Liu, C Y; Liu, F H; Liu, Fang; Liu, Feng; Liu, H; Liu, H B; Liu, H H; Liu, H M; Liu, H W; Liu, J P; Liu, K Y; Liu, Kai; Liu, P L; Liu, Q; Liu, S B; Liu, X; Liu, X H; Liu, Y B; Liu, Z A; Liu, Zhiqiang; Liu, Zhiqing; Loehner, H; Lu, G R; Lu, H J; Lu, J G; Lu, Q W; Lu, X R; Lu, Y P; Luo, C L; Luo, M X; Luo, T; Luo, X L; Lv, M; Ma, C L; Ma, F C; Ma, H L; Ma, Q M; Ma, S; Ma, T; Ma, X Y; Ma, Y; Maas, F E; Maggiora, M; Malik, Q A; Mao, Y J; Mao, Z P; Messchendorp, J G; Min, J; Min, T J; Mitchell, R E; Mo, X H; Morales, C Morales; Motzko, C; Muchnoi, N Yu; Muramatsu, H; Nefedov, Y; Nicholson, C; Nikolaev, I B; Ning, Z; Olsen, S L; Ouyang, Q; Pacetti, S; Park, J W; Pelizaeus, M; Peng, H P; Peters, K; Ping, J L; Ping, R G; Poling, R; Prencipe, E; Qi, M; Qian, S; Qiao, C F; Qin, X S; Qin, Y; Qin, Z H; Qiu, J F; Rashid, K H; Rong, G; Ruan, X D; Sarantsev, A; Schaefer, B D; Schulze, J; Shao, M; Shen, C P; Shen, X Y; Sheng, H Y; Shepherd, M R; Song, X Y; Spataro, S; Spruck, B; Sun, D H; Sun, G X; Sun, J F; Sun, S S; Sun, Y J; Sun, Y Z; Sun, Z J; Sun, Z T; Tang, C J; Tang, X; Tapan, I; Thorndike, E H; Toth, D; Ullrich, M; Varner, G S; Wang, B; Wang, B Q; Wang, K; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, Q; Wang, Q J; Wang, S G; Wang, X L; Wang, Y D; Wang, Y F; Wang, Y Q; Wang, Z; Wang, Z G; Wang, Z Y; Wei, D H; Weidenkaff, P; Wen, Q G; Wen, S P; Werner, M; Wiedner, U; Wu, L H; Wu, N; Wu, S X; Wu, W; Wu, Z; Xia, L G; Xiao, Z J; Xie, Y G; Xiu, Q L; Xu, G F; Xu, G M; Xu, H; Xu, Q J; Xu, X P; Xu, Z R; Xue, F; Xue, Z; Yan, L; Yan, W B; Yan, Y H; Yang, H X; Yang, Y; Yang, Y X; Ye, H; Ye, M; Ye, M H; Yu, B X; Yu, C X; Yu, J S; Yu, S P; Yuan, C Z; Yuan, Y; Zafar, A A; Zallo, A; Zeng, Y; Zhang, B X; Zhang, B Y; Zhang, C C; Zhang, D H; Zhang, H H; Zhang, H Y; Zhang, J Q; Zhang, J W; Zhang, J Y; Zhang, J Z; Zhang, S H; Zhang, X J; Zhang, X Y; Zhang, Y; Zhang, Y H; Zhang, Y S; Zhang, Z P; Zhang, Z Y; Zhao, G; Zhao, H S; Zhao, J W; Zhao, K X; Zhao, Lei; Zhao, Ling; Zhao, M G; Zhao, Q; Zhao, S J; Zhao, T C; Zhao, X H; Zhao, Y B; Zhao, Z G; Zhemchugov, A; Zheng, B; Zheng, J P; Zheng, Y H; Zhong, B; Zhong, J; Zhou, L; Zhou, X K; Zhou, X R; Zhu, C; Zhu, K; Zhu, K J; Zhu, S H; Zhu, X L; Zhu, X W; Zhu, Y C; Zhu, Y M; Zhu, Y S; Zhu, Z A; Zhuang, J; Zou, B S; Zou, J H

    2012-01-01

    The decay of $J/\\psi$ to three photons is studied using $\\psi^\\prime\\to\\pi^+\\pi^-J/\\psi$ in a sample of 106 million $\\psi^\\prime$ events collected with the BESIII detector. First evidence of the decay $\\eta_c\\to\\gamma\\gamma$ is reported, and the product branching fraction is determined to be $\\br{J/\\psi\\to\\gamma\\eta_c,\\eta_c\\to \\gamma\\gamma}=(4.5\\pm1.2\\pm0.6)\\times10^{-6}$, where the first error is statistical and the second systematic. The branching ratio for the direct decay is $\\br{J/\\psi\\to3\\gamma} = (11.3\\pm1.8\\pm2.0)\\times 10^{-6}$.

  2. The close-range gamma-graphy control - {gamma}-prox; Le controle par gammagraphie de proximite - {gamma}-prox

    Energy Technology Data Exchange (ETDEWEB)

    Blettner, A. [Institut de Soudure, 93 - Villepinte (France)

    2011-01-15

    This work deals with the {gamma}-prox: a modular device for proximity gamma-graphy. The dose rates obtained between the standard collimator and the {gamma}-prox are compared. A study, among the tools developed by the Welding Institute Industry, to estimate the occupational dosimetry is presented in order to determine the dose limits for a welding control of 255 mm diameter and 5 mm thickness, as well as the calculation of the signalling distances. (O.M.)

  3. New Scalar Contributions to $h\\to Z\\gamma$

    CERN Document Server

    Chen, Chian-Shu; Huang, Da; Tsai, Lu-Hsing

    2013-01-01

    We calculate the decay rate of $h\\to Z\\gamma$ by including the contributions from new scalars with arbitrary quantum numbers of the weak isospin ($T$) and hypercharge ($Y$) in the standard model. We find that our general formula for the decay rate of $h\\to Z\\gamma$ matches with that for $h\\to \\gamma\\gamma$ in the limit of $m_Z=0$, but it is different from those in the literature. To illustrate our result, by taking the current $2\\sigma$ excess of the $h\\to \\gamma\\gamma$rate measured by the LHC, we examine the corresponding shift for the $Z\\gamma$ decay channel due to the new scalar. We show that the enhancement or reduction of the $h\\to Z\\gamma$ rate only depends on the relative size of $T$ and the absolute value of $Y$. Explicitly, we predict $0.76gamma}\\equiv \\Gamma(h\\to Z\\gamma)/\\Gamma_{SM}(h\\to Z\\gamma)<2.05$ by imposing the observed range of $1.5gamma\\gamma}\\equiv \\Gamma(h\\to Z\\gamma\\gamma)/\\Gamma_{SM}(h\\to\\gamma\\gamma)<2$, which is independent of the number of multiplets and the c...

  4. Gravitational microlensing of gamma-ray blazars

    DEFF Research Database (Denmark)

    F. Torres, Diego; E. Romero, Gustavo; F. Eiroa, Ernesto;

    2003-01-01

    We present a detailed study of the effects of gravitational microlensing on compact and distant $\\gamma$-ray blazars. These objects have $\\gamma$-ray emitting regions which are small enough as to be affected by microlensing effects produced by stars lying in intermediate galaxies. We analyze...... the temporal evolution of the gamma-ray magnification for sources moving in a caustic pattern field, where the combined effects of thousands of stars are taken into account using a numerical technique. We propose that some of the unidentified $\\gamma$-ray sources (particularly some of those lying at high...... galactic latitude whose gamma-ray statistical properties are very similar to detected $\\gamma$-ray blazars) are indeed the result of gravitational lensing magnification of background undetected Active Galactic Nuclei (AGNs)....

  5. The topological filtration of $\\gamma$-structures

    CERN Document Server

    Li, Thomas J X

    2012-01-01

    In this paper we study $\\gamma$-structures filtered by topological genus. $\\gamma$-structures are a class of RNA pseudoknot structures that plays a key role in the context of polynomial time folding of RNA pseudoknot structures. A $\\gamma$-structure is composed by specific building blocks, that have topological genus less than or equal to $\\gamma$, where composition means concatenation and nesting of such blocks. Our main results are the derivation of a new bivariate generating function for $\\gamma$-structures via symbolic methods, the singularity analysis of the solutions and a central limit theorem for the distribution of topological genus in $\\gamma$-structures of given length. In our derivation specific bivariate polynomials play a central role. Their coefficients count particular motifs of fixed topological genus and they are of relevance in the context of genus recursion and novel folding algorithms.

  6. Repatriation of Gamma Chambers Exported by India

    International Nuclear Information System (INIS)

    The Board of Radiation and Isotope Technology (BRIT) is engaged in the production and supply of laboratory gamma chambers. The gamma chambers are self-shielded devices in which a number of 60Co source pencils placed in a cylindrical cage. The gamma chambers are type approved as a device and a transportation package separately by the Atomic Energy Regulatory Board. BRIT has exported number of such gamma chambers. For some of the gamma chambers, the type approval validity period is over and can no longer be transported. Hence, the radiation sources need to be transferred to a type approved package before transportation. BRIT has decommissioned five such gamma chambers so far and sources have been repatriated back to India. (author)

  7. The topological filtration of gamma-structures

    DEFF Research Database (Denmark)

    Li, T. J.; Reidys, C. M.

    2013-01-01

    topological genus less than or equal to gamma, where composition means concatenation and nesting of such blocks. Our main results are the derivation of a new bivariate generating function for gamma-structures via symbolic methods, the singularity analysis of the solutions and a central limit theorem......In this paper we study gamma-structures filtered by topological genus. gamma-structures are a class of RNA pseudoknot structures that plays a key role in the context of polynomial time folding of RNA pseudoknot structures. A gamma-structure is composed by specific building blocks, that have...... for the distribution of topological genus in gamma-structures of given length. In our derivation specific bivariate polynomials play a central role. Their coefficients count particular motifs of fixed topological genus and they are of relevance in the context of genus recursion and novel folding algorithms....

  8. Human Gamma Oscillations during Slow Wave Sleep

    OpenAIRE

    Mario Valderrama; Benoît Crépon; Vicente Botella-Soler; Jacques Martinerie; Dominique Hasboun; Catalina Alvarado-Rojas; Michel Baulac; Claude Adam; Vincent Navarro; Michel Le Van Quyen

    2012-01-01

    Neocortical local field potentials have shown that gamma oscillations occur spontaneously during slow-wave sleep (SWS). At the macroscopic EEG level in the human brain, no evidences were reported so far. In this study, by using simultaneous scalp and intracranial EEG recordings in 20 epileptic subjects, we examined gamma oscillations in cerebral cortex during SWS. We report that gamma oscillations in low (30-50 Hz) and high (60-120 Hz) frequency bands recurrently emerged in all investigated r...

  9. Understanding Doppler Broadening of Gamma Rays

    Energy Technology Data Exchange (ETDEWEB)

    Rawool-Sullivan, Mohini [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sullivan, John P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-07-03

    Doppler-broadened gamma ray peaks are observed routinely in the collection and analysis of gamma-ray spectra. If not recognized and understood, the appearance of Doppler broadening can complicate the interpretation of a spectrum and the correct identification of the gamma ray-emitting material. We have conducted a study using a simulation code to demonstrate how Doppler broadening arises and provide a real-world example in which Doppler broadening is found. This report describes that study and its results.

  10. Cross-Section of Hadron Production in $\\gamma\\gamma$ Collisions at LEP

    CERN Document Server

    Acciarri, M; Aguilar-Benítez, M; Ahlen, S P; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alverson, G; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Banerjee, S; Banerjee, Sw; Banicz, K; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Baschirotto, A; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Bilei, G M; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böck, R K; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brigljevic, V; Brock, I C; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Button, A M; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chekanov, S V; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chéreau, X J; Chiefari, G; Chien, C Y; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Cohn, H O; Coignet, G; Colijn, A P; Colino, N; Commichau, V; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Dai, T S; D'Alessandro, R; De Asmundis, R; Degré, A; Deiters, K; Della Volpe, D; Denes, P; De Notaristefani, F; DiBitonto, Daryl; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Duinker, P; Durán, I; Dutta, S; Easo, S; Efremenko, Yu V; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ernenwein, J P; Extermann, Pierre; Fabre, M; Faccini, R; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Fenyi, B; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Goldfarb, S; Goldstein, J; Gong, Z F; Gougas, Andreas; Gratta, Giorgio; Grünewald, M W; Gupta, V K; Gurtu, A; Gutay, L J; Hartmann, B; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Van Hoek, W C; Hofer, H; Hong, S J; Hoorani, H; Hou, S R; Hu, G; Innocente, Vincenzo; Jenkes, K; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kasser, A; Khan, R A; Kamrad, D; Kamyshkov, Yu A; Kapustinsky, J S; Karyotakis, Yu; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, D H; Kim, J K; Kim, S C; Kim, Y G; Kinnison, W W; Kirkby, A; Kirkby, D; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Korolko, I; Koutsenko, V F; Krämer, R W; Krenz, W; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lapoint, C; Lassila-Perini, K M; Laurikainen, P; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lu, W; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Majumder, G; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mangla, S; Marchesini, P A; Marin, A; Martin, J P; Marzano, F; Massaro, G G G; McNally, D; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mi, Y; Mihul, A; Van Mil, A J W; Mirabelli, G; Mnich, J; Molnár, P; Monteleoni, B; Moore, R; Morganti, S; Moulik, T; Mount, R; Müller, S; Muheim, F; Muijs, A J M; Nahn, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nippe, A; Nisati, A; Nowak, H; Oh, Yu D; Opitz, H; Organtini, G; Ostonen, R; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Park, H K; Park, I H; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pei, Y J; Pensotti, S; Perret-Gallix, D; Petersen, B; Petrak, S; Pevsner, A; Piccolo, D; Pieri, M; Pinto, J C; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Produit, N; Prokofev, D; Prokofiev, D O; Rahal-Callot, G; Raja, N; Rancoita, P G; Rattaggi, M; Raven, G; Razis, P A; Read, K; Ren, D; Rescigno, M; Reucroft, S; Van Rhee, T; Riemann, S; Riles, K; Robohm, A; Rodin, J; Roe, B P; Romero, L; Rosier-Lees, S; Rosselet, P; Van Rossum, W; Roth, S; Rubio, Juan Antonio; Ruschmeier, D; Rykaczewski, H; Salicio, J; Sánchez, E; Sanders, M P; Sarakinos, M E; Sarkar, S; Sassowsky, M; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schmitz, P; Scholz, N; Schopper, Herwig Franz; Schotanus, D J; Schwenke, J; Schwering, G; Sciacca, C; Sciarrino, D; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shukla, J; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Sopczak, André; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stone, H; Stoyanov, B; Strässner, A; Strauch, K; Sudhakar, K; Sultanov, G G; Sun, L Z; Susinno, G F; Suter, H; Swain, J D; Tang, X W; Tauscher, Ludwig; Taylor, L; Ting, Samuel C C; Ting, S M; Tonutti, M; Tonwar, S C; Tóth, J; Tully, C; Tuchscherer, H; Tung, K L; Uchida, Y; Ulbricht, J; Uwer, U; Valente, E; Van de Walle, R T; Vesztergombi, G; Vetlitskii, I; Viertel, Gert M; Vivargent, M; Völkert, R; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, J C; Wang, X L; Wang, Z M; Weber, A; Wittgenstein, F; Wu, S X; Wynhoff, S; Xu, J; Xu, Z Z; Yang, B Z; Yang, C G; Yao, X Y; Ye, J B; Yeh, S C; You, J M; Zalite, A; Zalite, Yu; Zemp, P; Zeng, Y; Zhang, Z; Zhang, Z P; Zhou, B; Zhu, G Y; Zhu, R Y; Zichichi, Antonino; Ziegler, F

    1997-01-01

    The reaction $\\mathrm{e}^{+} \\mathrm{e}^{-} \\rightarrow \\mathrm{e}^{+} \\mathrm{e}^{-} \\gamma ^{*} \\gamma ^{*} \\rightarrow \\mathrm{e}^{+} \\mathrm{e}^{-} $ {\\sl hadrons} is analysed using data collected by the L3 detector during the LEP runs at $\\sqrt {s}$ = 130-140 GeV and $\\sqrt {s}$ = 161 GeV. The cross sections $\\sigma(\\mathrm{e}^{+} \\mathrm{e}^{-} \\rightarrow \\mathrm{e}^{+} \\mathrm{e}^{-} $ {\\sl hadrons}) and $\\sigma (\\gamma\\gamma \\rightarrow $ {\\sl hadrons}) are measured in the interval 5 $\\leq W_{\\gamma\\gamma} \\leq$ 75 GeV. The energy dependence of the $\\sigma (\\gamma\\gamma \\rightarrow $ {\\sl hadrons}) cross section is consistent with the universal Regge behaviour of total hadronic cross sections. %\\end{abstract}

  11. TESLA*HERA Based gamma-p and gamma-A Colliders

    OpenAIRE

    Ciftci, A. K.; Sultansoy, S.; Yavas, O.

    2000-01-01

    Main parameters and physics search potential of gamma-p and gamma-A colliders, which will be available due to constructing the TESLA linear electron-positron collider tangentially to the HERA proton ring, are discussed.

  12. Application of conventional laser technology to gamma-gamma colliders

    International Nuclear Information System (INIS)

    A future e-e+ (electron-positron) linear collider can be configured with perhaps minimal modification to serve as an γ-γ (gamma-gamma) or a e--γ collider. This is accomplished by Compton-backscattering low energy photons (from a laser source) off of the high-energy electron beams prior to the crossing of the electron beams. However, to be competitive with the e-e+ configuration, the luminosity cannot be compromised in the process. This requires that the laser source deliver a sufficient number of photons per pulse with a pulse format and rate matching that of the electron beams. As it turns out, this requires an average optical power of 5 to 15 kW from the laser which is beyond the current state of the art. In this paper, the authors address how to generate the required pulse format and how the high average power requirement can be met with conventional laser technology. They also address concerns about the survivability of mirrors located near the interaction point. Finally, they list a program of research and development which addresses some of the unknowns in such a system

  13. Roy-Steiner equations for gamma gamma -> pi pi

    CERN Document Server

    Hoferichter, Martin; Schat, Carlos

    2011-01-01

    Starting from hyperbolic dispersion relations, we derive a system of Roy--Steiner equations for pion Compton scattering that respects analyticity, unitarity, gauge invariance, and crossing symmetry. It thus maintains all symmetries of the underlying quantum field theory. To suppress the dependence of observables on high-energy input, we also consider once- and twice-subtracted versions of the equations, and identify the subtraction constants with dipole and quadrupole pion polarizabilities. Based on the assumption of Mandelstam analyticity, we determine the kinematic range in which the equations are valid. As an application, we consider the resolution of the $\\gamma\\gamma\\to\\pi\\pi$ partial waves by a Muskhelishvili--Omn\\`es representation with finite matching point. We find a sum rule for the isospin-two $S$-wave, which, together with chiral constraints, produces an improved prediction for the charged-pion quadrupole polarizability $(\\alpha_2-\\beta_2)^{\\pi^\\pm}=(15.3\\pm 3.7)\\cdot 10^{-4} {\\rm fm}^5$. We inves...

  14. Multiple elliptic gamma functions associated to cones

    CERN Document Server

    Winding, Jacob

    2016-01-01

    We define generalizations of the multiple elliptic gamma functions and the multiple sine functions, associated to good rational cones. We explain how good cones are related to collections of $SL_r(\\mathbb{Z})$-elements and prove that the generalized multiple sine and multiple elliptic gamma functions enjoy infinite product representations and modular properties determined by the cone. This generalizes the modular properties of the elliptic gamma function studied by Felder and Varchenko, and the results about the usual multiple sine and elliptic gamma functions found by Narukawa.

  15. Radion production in gamma-electron collisions

    CERN Document Server

    Soa, D V; Thao, N H; Thuy, D T L; 10.1142/S021773231250126X

    2012-01-01

    We analyze the potential of Compact Linear Colliders based on the \\gamma-e collisions to search for the radion in the Randall-Sundrum model, where compactification radius of the extra dimension is stabilized by the radion, which is a scalar field lighter than the graviton Kaluza-Klein states. The radion production in the high energy \\gamma-e colliders with the polarization of the electron beams are calculated in detail. Numerical evaluation shows that if the radion mass is not too heavy with the mass order of GeV then the reaction can give observable cross section in future colliders at the high degree of polarization.

  16. Skyshine spectra of gamma rays

    International Nuclear Information System (INIS)

    A study of the spectra of gamma photons back-scattered in vertical direction by infinite air above ground (skyshine) is presented. The source for these measurements is a 650 Ci Cobalt-60 point-source and the skyshine spectra are reported for distances from 150 m to 325 m from the source, measured with a 5 cm x 5 cm NaI(Tl) detector collimated with collimators of 12 mm and 20 mm diameter and 5 cm length. These continuous spectra are unfolded with Gold's iterative technique. The photon-spectra so obtained have a distinct line at 72 keV due to multiply-scattered photons. This is an energy where photoelectric and Compton cross-sections for multiply-scattered photons balance each other. The intensity of the line(I) decreases exponentially with distance (d) from the source obeying a relation of the type I = Isub(o)esup(-μd) where μ is called as ''Multiply-Scatter Coefficient'', a constant of the medium which is air in these measurements. This relationship is explained in terms of a halo around the source comprising of multiply-scattered gamma photons, Isub(0) being the intensity of these scattered photons at the location of cobalt-source. A fraction called as ''Back-scattered Fraction'', the ratio of Isub(0) to the number of original photons from the cobalt-source entering the infinite air, is also calculated. It is shown that with a properly calibrated detector system, this fraction can be used to determine the strength of a large gamma source, viz. a nuclear explosion in air, and for mineral prospecting. These conclusions are general and can be applied to any other infinite medium. Some forward-scatter (transmission) spectra of cobalt-60 source through 10 cm of Pb and 2.5 cm of Al are also reported. (auth.)

  17. Performance Analysis of Decode-and-Forward Relaying in Gamma-Gamma Fading Channels

    CERN Document Server

    Bhatnagar, Manav R

    2012-01-01

    Decode-and-forward (DF) cooperative communication based on free space optical (FSO) links is studied in this letter. We analyze performance of the DF protocol in the FSO links following the Gamma-Gamma distribution. The cumulative distribution function (CDF) and probability density function (PDF) of a random variable containing mixture of the Gamma- Gamma and Gaussian random variables is derived. By using the derived CDF and PDF, average bit error rate of the DF relaying is obtained.

  18. Sterilization plants equipped with the isotopic gamma radiation sources

    International Nuclear Information System (INIS)

    Presentation describes different isotopic gamma radiation sources applicable for sterilization of food and medical materials. Certain gamma pallet irradiators, mini gamma irradiators and different scale gamma tote irradiators are presented. It is concluded, that about two hundreds plants with gamma radiation sources operates in different countries. However, industrially developed countries must construct much more plants than operates now

  19. Variance gamma process simulation and it's parameters estimation

    OpenAIRE

    Kuzmina, A. V.

    2010-01-01

    Variance gamma process is a three parameter process. Variance gamma process is simulated as a gamma time-change Brownian motion and as a difference of two independent gamma processes. Estimations of simulated variance gamma process parameters are presented in this paper.

  20. Measurement and analysis of the reaction. gamma. gamma. ->3. pi. sup + 3. pi. sup -

    Energy Technology Data Exchange (ETDEWEB)

    Pust, R.; Greenshaw, T.; Hagemann, J.; Heinzelmann, G.; Kleinwort, C.; Kuhlen, M.; Naroska, B.; Ould-Saada, F.; Pitzl, D.; Schneekloth, U.; Weber, G. (Hamburg Univ. (Germany, F.R.). 2. Inst. fuer Experimentalphysik); Olsson, J.; Bartel, W.; Felst, R.; Haidt, D.; Kado, H.; Knies, G.; Krehbiel, H.; Magnussen, N.; Meinke, R.; Ramcke, R.; Schmidt, D.; Steffen, P. (Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany, F.R.)); Allison, J.; Barlow, R.J.; Chrin, J.; Duerdoth, I.P.; Loebinger, F.K.; Macbeth, A.A.; Murphy, P.G.; Stephens, K. (Manchester Univ. (UK)); Ambrus, K.; Bethke, S.; Dieckmann, A.; Eckerlin, G.; Elsen, E.; Heintze, J.; Hellenbrand, K.H.; Komamiya, S.; Krogh, J. v.; Rieseberg, H.; Smolik, L.; Spitzer, J.; Wagner, A.; Zimmer, M. (Heidelberg Univ. (Germany, F.R.). Physikalisches Inst.); Bowdery, C.K.; Finch, A.J.; Foster, F.; Hughes, G.; Nye, J.M.; Walker, I.W. (Lancaster Univ. (UK)); Cartwright, S.L.; Clarke, D.; Marshall, R.; Middleton, R.P. (Rutherford Appleton L; JADE Collaboration

    1991-08-01

    The reaction {gamma}{gamma}->3{pi}{sup +}3{pi}{sup -} has been studied using the JADE detector at PETRA. The topological cross section {sigma} ({gamma}{gamma}->3{pi}{sup +}3{pi}{sup -}) was measured in the CM energy range 1.5-5.5 GeV. The production of rho{sup 0}'s was observed and the average number of rho{sup 0}'s per event measured. The contributions of the subprocesses {gamma}{gamma}->rho{sup 0}2{pi}{sup +}2{pi}{sup -}, {gamma}{gamma}->rho{sup 0}rho{sup 0}{pi}{sup +}{pi}{sup -} and {gamma}{gamma}->3{pi}{sup +}3{pi}{sup -} (phase space) were studied and 95% C.L. upper limits for the cross section {sigma}({gamma}{gamma}->rho{sup 0}rho{sup 0}{pi}{sup +}{pi}{sup -}) determined. Finally the Bose-Einstein correlation for pairs of like signed pions was observed. A fit to a standard parametrization gave results consistent with other studies of this effect in pion systems. (orig.).

  1. Test of compositeness in p anti p ->. gamma gamma. X processes

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Canal, C.A.; Grifols, J.A.; Mendez, A. (Universidad Autonoma de Barcelona (Spain). Dept. de Fisica Teorica)

    1984-10-11

    If composite spin-zero states are introduced in order to explain the measured abundance of Z -> e/sup +/e/sup -/..gamma.. events, it is shown that these states should be observed in the two-photon energy spectrum of p anti p -> ..gamma gamma..X. The possible choices for the coupling constants involved are discussed.

  2. AcAP5蛋白N端片段的表达、纯化与活性评价%Expression, purification and evaluation of N-terminal domain of AcAP5 with Factor Xa inhibitory activity

    Institute of Scientific and Technical Information of China (English)

    刘爱华; 朱元军; 刘晓岩; 王银叶

    2013-01-01

    Ancylostoma anticoagulant peptide 5 (AcAP5) is a strong inhibitor of human coagulation factor Xa (FXa).The N-terminal residues (N40) of AcAP5 contains a domain that could combine with FXa.In order to determine whether N40 protein has FXa inhibitory effect,we cloned,expressed and purified the protein for activity evaluation.The DNA fragment coding N40 was amplified by PCR,cloned into pET-30a to construct recombinant plasmid pET30a-N40,and subsequently transformed into E.coli.BL21 (DE3).Expression of N40 was induced by isopropyl β-D-l-thiogalactopyranoside (IPTG),and the interest protein was identified by SDS-PAGE and purified using one-step nickel (Ni) affinity chromatography.Under the optimal expression condition (0.05 mM IPTG for 6 h at 37 ℃),the purity of N40 reached 90%.We also evaluated the inhibition activity of N40 protein on FXa,finding the IC50 was 4.58× 10 5 mol/L.This study suggests the N40 of AcAP5 could combine with FXa to inhibit FXa activity.%犬钩虫抗凝肽5 (Ancylostoma anticoagulant peptide 5,AcAP5)N端40个氨基酸片段(N40)含有与FXa结合的结构域.为研究N40的FXa抑制作用,我们克隆、表达和纯化了N40,并检测其生物活性.用PCR扩增N40基因;将PCR产物克隆至原核表达载体pET-30a中,构建质粒pET30a-N40;将其转化入大肠杆菌E.coli.BL21 (DE3)中,IPTG诱导目的蛋白表达,SDS-PAGE电泳鉴定,经过镍柱亲和层析纯化,用BCA法进行蛋白定量,测定该蛋白抑制FXa的活性.限制性酶切鉴定和基因测序结果显示重组质粒构建成功;SDS-PAGE结果显示目的蛋白在E.coli.BL21(DE3)中为可溶性表达,亲和层析纯化后获得了纯度约90%的蛋白,经活性鉴定该蛋白确有抑制FXa的活性.

  3. Safety assessment of gamma-cyclodextrin.

    Science.gov (United States)

    Munro, I C; Newberne, P M; Young, V R; Bär, A

    2004-06-01

    Gamma-cyclodextrin (gamma-CD) is a cyclic alpha-(1,4)-linked oligosaccharide consisting of eight glucose molecules. Like other cyclodextrins, gamma-CD can form inclusion complexes with a variety of organic molecules because the inner side of the torus-like molecule is less polar than the outer side. In foods, gamma-CD may be used as a carrier for flavors, vitamins, polyunsaturated fatty acids, and other ingredients. It also has useful properties as a stabilizer in different food systems. The daily intake from all its intended uses in food at highest feasible concentrations has been estimated at 4.1g/person/day for consumers of gamma-CD containing foods. The present review summarizes the safety data of gamma-CD. The toxicity studies consist of standard genotoxicity tests, subchronic rat studies with oral and intravenous administration of gamma-CD for up to 3 months, a subchronic (3-month) toxicity study in dogs, a (1-year) oral toxicity study in rats, and embryotoxicity/teratogenicity studies in rats and rabbits. In the studies with oral administration, gamma-CD was given at dietary concentrations of up to 20%. All these studies demonstrated that gamma-CD is well tolerated and elicits no toxicological effects. Metabolic studies in rats showed that gamma-CD is rapidly and essentially completely digested by salivary and pancreatic amylase. Therefore, the metabolism of gamma-CD closely resembles that of starch and linear dextrins. A human study with ingestion of single doses of 8 g gamma-CD or 8 g maltodextrin did not reveal a difference in gastrointestinal tolerance of these two products. An interaction of ingested gamma-CD with the absorption of fat-soluble vitamins or other lipophilic nutrients is not to be expected because the formation of inclusion complexes is a reversible process, gamma-CD is readily digested in the small intestine, and studies with beta-CD, a non-digestible cyclodextrin, have shown that the bioavailability of vitamins (A, D, and E) is not

  4. Gemstone dedicated gamma irradiation development

    Energy Technology Data Exchange (ETDEWEB)

    Omi, Nelson M.; Rela, Paulo R. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: nminoru@ipen.br; prela@ipen.br

    2007-07-01

    The gemstones gamma irradiation process to enhance the color is widely accepted for the jewelry industry. These gems are processed in conventional industrial gamma irradiation plant which are optimized for other purposes, using underwater irradiation devices with high rejection rate due to its poor dose uniformity. A new conception design, which states the working principles and manufacturing ways of the device, was developed in this work. The suggested device's design is based on the rotation of cylindrical baskets and their translation in circular paths inside and outside a cylindrical source rack as a planetary system. The device is meant to perform the irradiation in the bottom of the source storage pool, where the sources remain always shielded by the water layer. The irradiator matches the Category III IAEA classification. To verify the physical viability of the basic principle, tests with rotating cylindrical baskets were performed in the Multipurpose Irradiator constructed in the CTR, IPEN. Also, simulations using the CADGAMMA software, adapted to simulate underwater irradiations, were performed. With the definitive optimized irradiator, the irradiation quality will be enhanced with better dose control and the production costs will be significantly lower than market prices due to the intended treatment device's optimization. This work presents some optimization parameters and the expected performance of the irradiator. (author)

  5. Gamma Irradiation of Polyesters Film

    International Nuclear Information System (INIS)

    Experimental investigations on the effects of gamma irradiation in air of aromatic polyesters are carried out, in order to evaluate the influence of aromatic density and the role of oxygen on the radiation resistance. The thermoplastic polyesters PolyEthyleneTerephthalate (PET), PolyButylene Terephthalate (PBT), PolyEthyleneNaphthalate (PEN), Poly1,4-cyclohexanedimethylen terephthalate-co-ethyleneterephthalate (PCT-co-ET) are moulded in thin films of 50 micron and irradiated at different absorbed doses, ranging from 0 to 1000 kGy, using a Co-60 gamma source. The structural changes in the polymers are studied by means of several physical-chemical and nuclear techniques. Electron Paramagnetic Resonance analyses are carried out to detect the radicals induced by irradiation and to follow their decay by oxygen permeation. Viscometric measurements show a similar trend for the different irradiated polyesters: in particular, chain scission induced by irradiation depends on the aromatic density contained in the polymer and shows a saturation effect at the highest doses. Positron Annihilation Lifetime Spectroscopy points out a decrease of the ortho-positronium signal caused by the production of oxidized species inhibiting the positronium formation. Finally, the experimental results obtained on the irradiated films are compared with previous studies carried out on the same polyesters moulded in sheets of 1-2 mm of thickness and γ-irradiated at the same adsorbed doses

  6. Food irradiation: Gamma processing facilities

    Energy Technology Data Exchange (ETDEWEB)

    Kunstadt, P. [MDS Nordion International, 447 March Road. Kanata, Ontario, K2K148 (Canada)

    1997-12-31

    The number of products being radiation processed is constantly increasing and today include such diverse items as medical disposable, fruits and vegetables, bulk spices, meats, sea foods and waste effluents. Not only do the products differ but also many products, even those within the same groupings, require different minimum and maximum radiation doses. These variations create many different requirements in the irradiator design. The design of Cobalt-60 radiation processing facilities is well established for a number of commercial applications. Installations in over 40 countries, with some in operation since the early 1960s, are testimony to the fact that irradiator design, manufacture, installation and operation is a well established technology. However, in order to design gamma irradiators for the preservation of foods one must recognize those parameters typical to the food irradiation process as well as those systems and methods already well established in the food industry. This paper discusses the basic design concepts for gamma food irradiators. They are most efficient when designed to handle a limited product density range at an established dose. Safety of Cobalt-60 transport, safe facility operation principles and the effect of various processing parameters on economics, will also be discussed. (Author)

  7. Gamma scale chemistry progress report

    Energy Technology Data Exchange (ETDEWEB)

    Economides, M.; Estabrook, E.; Joy, E.F. [and others

    1948-06-01

    This report considers the work done during the year ending June 30, 1948, present work being done and future plans on the determination of formulas, methods of preparation, and properties of as many compounds of postum as possible. An experimental approach to such a research problem on the element postum requires that procedures which may be used deal with ultramicro quantities of material. Such procedures on an ultramicro or gamma scale require special techniques by personnel trained in manipulating these small quantities of radioactive material. Equipment which may be used varies with the experiment considered. Often new apparatus must be developed or equipment previously developed and used in some other experiment must be modified. This generalized research problem is subdivided in the {open_quotes}Research Problems Outline{close_quotes}. The presentation of a survey of these research problems with reference to the outline for the year ending June 30, 1948 is a critical review of the work done by the Gamma Scale Chemistry Group as well as a consideration of future plans. The course which these future plans may follow will depend upon information which may be obtained when carrying out planned experiments.

  8. Food irradiation: Gamma processing facilities

    International Nuclear Information System (INIS)

    The number of products being radiation processed is constantly increasing and today include such diverse items as medical disposable, fruits and vegetables, bulk spices, meats, sea foods and waste effluents. Not only do the products differ but also many products, even those within the same groupings, require different minimum and maximum radiation doses. These variations create many different requirements in the irradiator design. The design of Cobalt-60 radiation processing facilities is well established for a number of commercial applications. Installations in over 40 countries, with some in operation since the early 1960s, are testimony to the fact that irradiator design, manufacture, installation and operation is a well established technology. However, in order to design gamma irradiators for the preservation of foods one must recognize those parameters typical to the food irradiation process as well as those systems and methods already well established in the food industry. This paper discusses the basic design concepts for gamma food irradiators. They are most efficient when designed to handle a limited product density range at an established dose. Safety of Cobalt-60 transport, safe facility operation principles and the effect of various processing parameters on economics, will also be discussed. (Author)

  9. Photon structure functions and azimuthal correlations of lepton pairs in tagged $\\gamma\\gamma$ collisions

    CERN Document Server

    Acciarri, M; Aguilar-Benítez, M; Ahlen, S P; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Ball, R C; Banerjee, S; Banerjee, Sw; Banicz, K; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Baschirotto, A; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Bilei, G M; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böck, R K; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Boutigny, D; Braccini, S; Branson, J G; Brigljevic, V; Brock, I C; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chekanov, S V; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chen, M; Chiefari, G; Chien, C Y; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colijn, A P; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Dai, T S; D'Alessandro, R; De Asmundis, R; Degré, A; Deiters, K; Denes, P; De Notaristefani, F; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Drago, E; Duchesneau, D; Duinker, P; Durán, I; Easo, S; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ernenwein, J P; Extermann, Pierre; Fabre, M; Faccini, R; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gerald, J; Gheordanescu, N; Giagu, S; Goldfarb, S; Goldstein, J; Gong, Z F; Gougas, Andreas; Gratta, Giorgio; Grünewald, M W; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hartmann, B; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Van Hoek, W C; Hofer, H; Hoorani, H; Hou, S R; Hu, G; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kasser, A; Khan, R A; Kamrad, D; Kapustinsky, J S; Karyotakis, Yu; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, D H; Kim, J K; Kim, S C; Kinnison, W W; Kirkby, A; Kirkby, D; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Korolko, I; Koutsenko, V F; Krämer, R W; Krenz, W; Kunin, A; Lacentre, P E; Ladrón de Guevara, P; Landi, G; Lapoint, C; Lassila-Perini, K M; Laurikainen, P; Lavorato, A; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Leggett, C; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lu, W; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Majumder, G; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Marchesini, P A; Marian, G; Marin, A; Martin, J P; Marzano, F; Massaro, G G G; Mazumdar, K; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mi, Y; Migani, D; Mihul, A; Van Mil, A J W; Milcent, H; Mirabelli, G; Mnich, J; Molnár, P; Monteleoni, B; Moore, R; Moulik, T; Mount, R; Muheim, F; Muijs, A J M; Nahn, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nippe, A; Nisati, A; Nowak, H; Oh, Yu D; Organtini, G; Ostonen, R; Palit, S; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Park, H K; Park, I H; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pei, Y J; Pensotti, S; Perret-Gallix, D; Petersen, B; Petrak, S; Pevsner, A; Piccolo, D; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Produit, N; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Raja, N; Rancoita, P G; Rattaggi, M; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Van Rhee, T; Riemann, S; Riles, K; Rind, O; Robohm, A; Rodin, J; Roe, B P; Romero, L; Rosier-Lees, S; Rosselet, P; Roth, S; Rubio, Juan Antonio; Ruschmeier, D; Rykaczewski, H; Salicio, J; Sánchez, E; Sanders, M P; Sarakinos, M E; Sauvage, G; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schneegans, M; Scholz, N; Schopper, Herwig Franz; Schotanus, D J; Schwenke, J; Schwering, G; Sciacca, C; Sciarrino, D; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shukla, J; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Soulimov, V; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, H; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z

    1998-01-01

    Measurements of the QED structure of the photon based on the reaction ee to ee gamma /sup (*)/(P/sup 2/) gamma *(Q/sup 2/) to ee mu mu are discussed. This review is an update of the discussion of the results on the QED structure of the photon and covers the published measurements of the photon structure functions F/sub 2//sup gamma /, F/sub A//sup gamma / and F/sub B//sup gamma / and of the differential cross-section d sigma /dx for the exchange of two virtual photons. (10 refs).

  10. Games with gammas: problems in environmental gamma dose determination

    International Nuclear Information System (INIS)

    The evaluation of the environmental dose rate is fundamental to ESR, OTL and TL dating, but results from different measurement methods, independently calibrated, are not always consistent. Some field measurements of environmental dose rate using a Canberra field gamma spectrometer are compared with those obtained using TLD and show a systematic discrepancy close to a factor of two. Possible reasons for the discrepancy are discussed but none offers a sufficiently substantial adjustment to reconcile the disagreement in the results given by the two methods. Comparison with dose rates estimated from radionuclide concentrations could not determine which method was more accurate as the correlation between these estimates and the previous ones was negligible, casting some doubt on the accuracy of the concentration estimates. The danger of relying on a single method of estimating dose rate without careful cross-calibration is highlighted. (author)

  11. Prompt gamma-ray activation analysis (PGAA)

    Energy Technology Data Exchange (ETDEWEB)

    Kern, J. [Fribourg Univ. (Switzerland). Inst. de Physique

    1996-11-01

    The paper deals with a brief description of the principles of prompt gamma-ray activation analysis (PGAA), with the detection of gamma-rays, the PGAA project at SINQ and with the expected performances. 8 figs., 3 tabs., 10 refs.

  12. Intercomparison of gamma ray analysis software packages

    International Nuclear Information System (INIS)

    The IAEA undertook an intercomparison exercise to review available software for gamma ray spectra analysis. This document describes the methods used in the intercomparison exercise, characterizes the software packages reviewed and presents the results obtained. Only direct results are given without any recommendation for a particular software or method for gamma ray spectra analysis

  13. Gamma-hydroxybutyrate abuse and dependence

    NARCIS (Netherlands)

    Noorden, M.S. van; Kamal, R.M.; Dijkstra, B.A.G.; Brunt, T.M.; Jong, C.A.J. de

    2016-01-01

    Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid that naturally occurs in the brain, where it acts as a neurotransmitter and as a neuromodulator. GHB is a gamma-aminobutyric acid (GABA) analogue that passes the blood–brain barrier. GHB exerts its actions by binding to the GHB receptor

  14. Gamma spectrometric assessment of nuclear fuel

    Science.gov (United States)

    Krištof, Edvard; Pregl, Gvido

    1990-12-01

    A description is given of a gamma spectrometric technique which has been developed with the aim of determining the amount of a certain radioactive fission product taking into consideration local variations of the linear attenuation coefficient of gamma rays. Also, an experiment using a fuel element of the TRIGA Mark II reactor in Ljubljana is presented.

  15. Gamma-hydroxybutyrate abuse and dependence

    NARCIS (Netherlands)

    Noorden, M.S. van; Kamal, R.M.; Dijkstra, B.A.G.; Brunt, T.M.; Jong, C.A.J. de

    2016-01-01

    Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid that naturally occurs in the brain, where it acts as a neurotransmitter and as a neuromodulator. GHB is a gamma-aminobutyric acid (GABA) analogue that passes the blood–brain barrier. GHB exerts its actions by binding to the GHB receptor in the

  16. A gamma model for {DNA} mixture analyses

    OpenAIRE

    Cowell, R. G.; Lauritzen, S L; Mortera, J.

    2007-01-01

    We present a new methodology for analysing forensic identification problems involving DNA mixture traces where several individuals may have contributed to the trace. The model used for identification and separation of DNA mixtures is based on a gamma distribution for peak area values. In this paper we illustrate the gamma model and apply it on several real examples from forensic casework.

  17. Handbook on Mobile Gamma-ray Spectrometry

    DEFF Research Database (Denmark)

    Aage, Helle Karina; Korsbech, Uffe C C

    2003-01-01

    Basic physics and mathematics for Airborne and Car-borne Gamma-ray Spectrometry supplemented with practical examples and methods for advanced data processing......Basic physics and mathematics for Airborne and Car-borne Gamma-ray Spectrometry supplemented with practical examples and methods for advanced data processing...

  18. Which multivariate gamma distributions are infinitely divisible?

    OpenAIRE

    Bernardoff, Philippe

    2006-01-01

    We define a multivariate gamma distribution on [math] by its Laplace transform [math] , [math] where ¶ [math] ¶ Under [math] , we establish necessary and sufficient conditions on the coefficients of [math] such that the above function is the Laplace transform of some probability distribution, for all [math] thus characterizing all infinitely divisible multivariate gamma distributions on [math

  19. Colliding. gamma. e and. gamma gamma. beams based in single-pass e/sup +/e/sup -/ accelerators. Pt. 2. Polarization effects, monochromatization improvement

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Panfil, S.L.; Telnov, V.I.

    Polarization effects are considered in colliding ..gamma..e and ..gamma gamma.. beams, which are proposed to be obtained on the basis of linear e/sup +/e/sup -/ colliders (by backward Compton scattering of laser light on electron beams). It is shown that using electrons and laser photons with helicities lambda and Psub(c), such that lambdaPsub(c) < 0, essentially improves the monochromatization. The characteristic laser flash energy, A/sub 0/, which is necessary to obtain a conversion coefficient k proportional 1 with a definite degree of monochromatization, is considerably less (somestimes by one order of magnitude) in the case 2 lambdaPsub(c) = -1 in contrast to the case lambdaPsub(c) = 0. Simultaneously the luminosities Lsub(..gamma..e) and Lsub(..gamma gamma..) essentially increase. Formulae are obtained which allow one to extract the polarization information about ..gamma..e -> X and ..gamma gamma.. -> X reactions. Perculiarities connected with the specific scheme of the ..gamma.. beam preparation are discussed. Problems of the calibration of the ..gamma..e and ..gamma gamma.. collisions for the polarized beams are discussed.

  20. The GAMMA-400 gamma-ray telescope characteristics. Angular resolution and electrons/protons separation

    CERN Document Server

    Leonov, A A; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Boyarchuk, K A; Castellini, G; Cattaneo, P W; Cumani, P; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2014-01-01

    The measurements of gamma-ray fluxes and cosmic-ray electrons and positrons in the energy range from 100 MeV to several TeV, which will be implemented by the specially designed GAMMA-400 gamma-ray telescope, concern with the following broad range of science topics. Searching for signatures of dark matter, surveying the celestial sphere in order to study gamma-ray point and extended sources, measuring the energy spectra of Galactic and extragalactic diffuse gamma-ray emission, studying gamma-ray bursts and gamma-ray emission from the Sun, as well as high precision measuring spectra of high-energy electrons and positrons, protons and nuclei up to the knee. To clarify these scientific problems with the new experimental data the GAMMA-400 gamma-ray telescope possesses unique physical characteristics comparing with previous and present experiments. For gamma-ray energies more than 100 GeV GAMMA-400 provides the energy resolution of ~1% and angular resolution better than 0.02 deg. The methods developed to reconstru...

  1. HIGGS PHYSICS WITH A GAMMA GAMMA COLLIDER BASED ON CLIC 1*.

    Energy Technology Data Exchange (ETDEWEB)

    ASNER,D.; BURKHARDT,H.; DE ROECK,A.; ELLIS,J.; GRONBERG,J.; HEINEMEYER,S.; SCHMITT,M.; SCHULTE,D.; VELASCO,M.; ZIMMERMAN,F.

    2001-11-01

    We present the machine parameters and physics capabilities of the CLIC Higgs Experiment (CLICHE), a low-energy {gamma}{gamma} collider based on CLIC 1, the demonstration project for the higher-energy two-beam accelerator CLIC. CLICHE is conceived as a factory capable of producing around 20,000 light Higgs bosons per year. We discuss the requirements for the CLIC 1 beams and a laser backscattering system capable of producing a {gamma}{gamma} total (peak) luminosity of 2.0 (0.36) x 10{sup 34} cm{sup -2} s{sup -1} with E{sub CM}({gamma}{gamma}) 115 GeV. We show how CLICHE could be used to measure accurately the mass, {bar b}b, WW and {gamma}{gamma} decays of a light Higgs boson. We illustrate how these measurements may distinguish between the Standard Model Higgs boson and those in supersymmetric and more general two-Higgs-doublet models, complementing the measurements to be made with other accelerators. We also comment on other prospects in {gamma}{gamma} and e{sup -}{gamma} physics with CLICHE.

  2. Software tool for xenon gamma-ray spectrometer control

    Science.gov (United States)

    Chernysheva, I. V.; Novikov, A. S.; Shustov, A. E.; Dmitrenko, V. V.; Pyae Nyein, Sone; Petrenko, D.; Ulin, S. E.; Uteshev, Z. M.; Vlasik, K. F.

    2016-02-01

    Software tool "Acquisition and processing of gamma-ray spectra" for xenon gamma-ray spectrometers control was developed. It supports the multi-windows interface. Software tool has the possibilities for acquisition of gamma-ray spectra from xenon gamma-ray detector via USB or RS-485 interfaces, directly or via TCP-IP protocol, energy calibration of gamma-ray spectra, saving gamma-ray spectra on a disk.

  3. Reaction Rate Sensitivity of the gamma-Process Path

    OpenAIRE

    Rauscher, T.

    2004-01-01

    The location of the (gamma,p)/(gamma,n) and (gamma,alpha)/(gamma,n) line at gamma-process temperatures is discussed, using recently published reaction rates based on global Hauser-Feshbach calculations. The results can directly be compared to previously published, classic gamma-process discussions. The nuclei exhibiting the largest sensitivity to uncertainties in nuclear structure and reaction parameters are specified.

  4. Study of $\\psi(2S)$ decays into $\\gamma K^+K^-$ and $\\gamma \\pi^+\\pi^-$

    CERN Document Server

    Ablikim, M; Bai, J Z; Ban, Y; Cai, X; Chen, H F; Chen, H S; Chen, H X; Chen, J C; Chen, Jin; Chen, Y B; Chu, Y P; Dai, Y S; Diao, L Y; Deng, Z Y; Dong, Q F; Du, S X; Fang, J; Fang, S S; Fu, C D; Gao, C S; Gao, Y N; Gu, S D; Gu, Y T; Guo, Y N; Guo, Z J; Harris, F A; LHe, K; He, M; Heng, Y K; Hou, J; Hu, H M; Hu, J H; Hu, T; Huang, X T; Ji, X B; Jiang, X S; Jiang, X Y; Jiao, J B; Jin, D P; Jin, S; Lai, Y F; Li, G; Li, H B; Li, J; Li, R Y; Li, S M; Li, W D; Li, W G; Li, X L; Li, X N; Li, X Q; Liang, Y F; Liao, H B; Liu, B J; Liu, C X; Liu, F; Liu, Fang; Liu, H H; Liu, H M; Liu, J; Liu, J B; Liu, J P; Liu, Jian; Liu, Q; Liu, R G; Liu, Z A; Lou, Y C; Lu, F; Lu, G R; Lu, J G; Lundborg, A; Luo, C L; Ma, F C; Ma, H L; Ma, L L; Ma, Q M; Mao, Z P; Mo, X H; Nie, J; Olsen, S L; Ping, R G; Qi, N D; Qin, H; Qiu, J F; Ren, Z Y; Rong, G; Ruan, X D; Shan, L Y; Shang, L; Shen, C P; Shen, D L; Shen, X Y; Sheng, H Y; Sun, H S; Sun, S S; Sun, Y Z; Sun, Z J; Tang, X; Tong, G L; Varner, G S; Wang, D Y; Wang, L; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, Y F; Wang, Z; Wang, Z Y; Wang, Zheng; Wei, C L; Wei, D H; Weng, Y; Wiedner, U; Wu, N; Xia, X M; Xie, X X; Xu, G F; Xu, X P; Xu, Y; Yan, M L; Yang, H X; Yang, Y X; Ye, M H; Ye, Y X; Yu, G W; Yuan, C Z; Yuan, Y; Zhang, S L; Zeng, Y; Zhang, B X; Zhang, B Y; Zhang, C C; Zhang, D H; Zhang, H Q; Zhang, H Y; Zhang, J W; Zhang, J Y; Zhang, S H; Zhang, X Y; Zhang, Yiyun; Zhang, Z X; Zhang, Z P; Zhao, D X; Zhao, W J; Zhao, M G; Zhao, P P; Zhao, W R; Zhao, Z G; Zheng, H Q; Zheng, J P; Zheng, Z P; Zhou, L; Zhu, K J; Zhu, Q M; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, B A; Zhuang, X A; Zou, B S

    2007-01-01

    Radiative charmonium decays from the BESII sample of 14$\\times10^{6}$ $\\psi(2S)$-events into two different final states, $\\gamma K^+K^-$ and $\\gamma\\pi^+\\pi^-$, are analyzed. Product branching fractions for $\\psi(2S)\\to\\gamma X\\to \\gamma\\pi^+\\pi^-$, $\\gamma K^+K^-$ are given, where $X=f_2(1270)$, $f_0(1500)$, and $f_0(1710)$ in $\\pi^+\\pi^-$ and $f_2(1270)$, $f_2'(1525)$, and $f_0(1700)$ in $K^+K^-$. An angular analysis gives the ratios of the helicity projections for the $f_2(1270)$ in $\\psi(2S)\\to\\gamma f_2(1270)\\to\\gamma\\pi^+\\pi^-$.

  5. Fabrication of gamma sources using the neutron-gamma reactions of 238Pu13C

    International Nuclear Information System (INIS)

    A production campaign for 238Pu13C sources with gamma fluence ranging from 2500 to 4500 gamma/s/4π at 6.13 MeV was carried out in 2002 in Atalante. An experimental study was undertaken to prepare the 238PuC mixture, which is the most delicate step. This procedure is described together with the other steps in the source fabrication process: purification of a plutonium oxide batch, preparation of a nitric solution of 238Pu, measurement of the gamma fluence of the PuC mixture before and after insertion into each of the two stainless steel capsules that constitute a PuN2O package, welding of the second envelope followed by leak testing, final measurement of the gamma fluence of the sealed source. This PuC sources fabrication procedure is effective: all the sources include the required gamma activity with an uncertainty on the gamma fluence of less than 10%. (authors)

  6. The Space-Based Gamma-Ray Telescope GAMMA-400 and Its Scientific Goals

    CERN Document Server

    Galper, A M; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Avanesov, G A; Bergstrom, L; Bogomolov, E A; Boezio, M; Bonvicini, V; Boyarchuk, K A; Dogiel, V A; Gusakov, Yu V; Fradkin, M I; Fuglesang, Ch; Hnatyk, B I; Kachanov, V A; Kadilin, V V; Kaplin, V A; Kheymits, M D; Korepanov, V; Larsson, J; Leonov, A A; Longo, F; Maestro, P; Marrocchesi, P; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Runtso, M F; Ryde, F; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Topchiev, N P; Vacchi, A; Vannuccini, E; Vasiliev, G I; Yurkin, Yu T; Zampa, N; Zarikashvili, V N; Zverev, V G

    2013-01-01

    The design of the new space-based gamma-ray telescope GAMMA-400 is presented. GAMMA-400 is optimized for the energy 100 GeV with the best parameters: the angular resolution ~0.01 deg, the energy resolution ~1%, and the proton rejection factor ~10E6, but is able to measure gamma-ray and electron + positron fluxes in the energy range from 100 MeV to 10 TeV. GAMMA-400 is aimed to a broad range of science topics, such as search for signatures of dark matter, studies of Galactic and extragalactic gamma-ray sources, Galactic and extragalactic diffuse emission, gamma-ray bursts, as well as high-precision measurements of spectra of cosmic-ray electrons + positrons, and nuclei.

  7. Production of modified starches by gamma irradiation

    International Nuclear Information System (INIS)

    As a new processing method for the production of modified starch, gamma irradiation and four kinds of inorganic peroxides were applied to commercial corn starch. The addition of inorganic peroxides without gamma irradiation or gamma irradiation without the addition of inorganic peroxides effectively decreased initial viscosity, but did not sufficiently keep viscosity stable. The combination of adding ammonium persulfate (APS) and gamma irradiation showed the lowest initial viscosity and the best stability out of the tested four kinds of inorganic peroxides. Among the tested mixing methods of APS, soaking was found to be more effective than dry blending or spraying. Therefore, the production of modified starch with low viscosity as well as with sufficient viscosity stability became feasible by the control of gamma irradiation dose levels and the amount of added APS to starch

  8. GEANT simulation of the $\\gamma$ nuclear gauge

    CERN Document Server

    Ouardi, A; Benchekroun, D; Hoummada, A

    2003-01-01

    The gamma nuclear gauging technique used for monitoring the sediment load suspended in water, is based on the detection of gamma rays emitted by a radioactive source. The GEANT321 Monte Carlo simulation tool, originally developed at CERN for high energy physics experiments, is used for the evaluation and calibration of gamma nuclear gauges. A set of parameters, principally the source energy, the source-detector separation, the lead block thickness and the energy threshold below which the sediments elemental composition affects the measurement or the energy corresponding to the Compton and photoelectric windows separation, are discussed and evaluated in the case of the gamma scattering gauge. For the gamma transmission gauge, the GEANT321 code has been used to define the optimal source detector distance interval, particularly for the Moroccan sediment samplers, and to check the influence of the radionuclide existing in the suspension, on the gauge response accuracy. Experimental calibration was also carried ou...

  9. Librarian driven analysis of gamma ray spectra

    International Nuclear Information System (INIS)

    For a set of a priori given radionuclides extracted from a general nuclide data library, the authors use median estimates of the gamma-peak areas and estimates of their errors to produce a list of possible radionuclides matching gamma ray line(s). The identification of a given radionuclide is obtained by searching for a match with the energy information of a database. This procedure is performed in an interactive graphic mode by markers that superimpose, on the spectral data, the energy information and yields provided by a general gamma ray data library. This library of experimental data includes approximately 17,000 gamma ray energy lines related to 756 known gamma emitter radionuclides listed by the ICRP. (author)

  10. Simultaneous beta/gamma digital spectroscopy

    Science.gov (United States)

    Farsoni, Abdollah T.

    A state-of-the-art radiation detection system for simultaneous spectroscopy of beta-particles and gamma-rays has been developed. The system utilizes a triple-layer phoswich detector and a customized Digital Pulse Processor (DPP) built in our laboratory. The DPP board was designed to digitally capture the analog signal pulses and, following several digital preprocessing steps, transfer valid pulses to the host computer for further digital processing. A MATLAB algorithm was developed to digitally discriminate beta and gamma events and reconstruct separate beta and gamma-ray energy spectra with minimum crosstalk. The spectrometer proved to be an effective tool for recording separate beta and gamma-ray spectra from mixed radiation fields. The system as a beta-gamma spectrometer will have broad-ranging applications in nuclear non-proliferation, radioactive waste management, worker safety, systems reliability, dose assessment, and risk analysis.

  11. Gamma-ray pulsars: a gold mine

    CERN Document Server

    Grenier, Isabelle A

    2015-01-01

    The most energetic neutron stars, powered by their rotation, are capable of producing pulsed radiation from the radio up to gamma rays with nearly TeV energies. These pulsars are part of the universe of energetic and powerful particle accelerators, using their uniquely fast rotation and formidable magnetic fields to accelerate particles to ultra-relativistic speed. The extreme properties of these stars provide an excellent testing ground, beyond Earth experience, for nuclear, gravitational, and quantum-electrodynamical physics. A wealth of gamma-ray pulsars has recently been discovered with the Fermi Gamma-Ray Space Telescope. The energetic gamma rays enable us to probe the magnetospheres of neutron stars and particle acceleration in this exotic environment. We review the latest developments in this field, beginning with a brief overview of the properties and mysteries of rotation-powered pulsars, and then discussing gamma-ray observations and magnetospheric models in more detail.

  12. High Energy Radiation from $\\gamma$ Ray Bursts

    CERN Document Server

    Dermer, C D; Dermer, Charles D.; Chiang, James

    1999-01-01

    Gamma-ray burst (GRB) engines are probed most intimately during the prompt gamma-ray luminous phase when the expanding blast wave is closest to the explosion center. Using GRBs 990123 and 940217 as guides, we briefly review observations of high-energy emission from GRBs and summarize some problems in GRB physics. \\gamma\\gamma transparency arguments imply relativistic beaming. The parameters that go into the external shock model are stated, and we show numerical simulation results of gamma-ray light curves from relativistic blast waves with different amounts of baryon loading. A distinct component due to the synchrotron self-Compton process produces significant emission at GeV and TeV energies. Predictions for spectral and temporal evolution at these energies are presented for a blast wave expanding into uniform surroundings. Observations of the slow decay of GeV-TeV radiation provide evidence for ultra-high energy cosmic ray acceleration in GRBs.

  13. Gamma Knife Radiosurgery for Acromegaly

    Directory of Open Access Journals (Sweden)

    John D. Rolston

    2012-01-01

    Full Text Available Acromegaly is debilitating disease occasionally refractory to surgical and medical treatment. Stereotactic radiosurgery, and in particular Gamma Knife surgery (GKS, has proven to be an effective noninvasive adjunct to traditional treatments, leading to disease remission in a substantial proportion of patients. Such remission holds the promise of eliminating the need for expensive medications, along with side effects, as well as sparing patients the damaging sequelae of uncontrolled acromegaly. Numerous studies of radiosurgical treatments for acromegaly have been carried out. These illustrate an overall remission rate over 40%. Morbidity from radiosurgery is infrequent but can include cranial nerve palsies and hypopituitarism. Overall, stereotactic radiosurgery is a promising therapy for patients with acromegaly and deserves further study to refine its role in the treatment of affected patients.

  14. Gamma irradiation service in Mexico

    International Nuclear Information System (INIS)

    In 1980 it was installed in Mexico, on the National Institute of Nuclear Research, an irradiator model J S-6500 of a canadian manufacture. Actually, this is the greatest plant in the Mexican Republic that offers a gamma irradiation process at commercial level to diverse industries. However, seeing that the demand for sterilize those products were not so much as the irradiation capacity it was opted by the incursion in other types of products. During 17 years had been irradiated a great variety of products grouped of the following form: dehydrated foods, disposable products for medical use, cosmetics, medicaments, various. Nowadays the capacity of the irradiator is saturated virtue of it is operated the 24 hours during the 365 days of the year and only its operation is suspended by the preventive and corrective maintenance. However, the fresh food market does not be attended since this irradiator was designed for doses greater than 10 kGy (1.0 Mrad)

  15. Durability Assessment of Gamma Tial

    Science.gov (United States)

    Draper, Susan L.; Lerch, Bradley A.; Pereira, J. Michael; Miyoshi, Kazuhisa; Arya, Vinod K.; Zhuang, Wyman

    2004-01-01

    Gamma TiAl was evaluated as a candidate alloy for low-pressure turbine blades in aeroengines. The durability of g-TiAl was studied by examining the effects of impact or fretting on its fatigue strength. Cast-to-size Ti-48Al-2Cr-2Nb was studied in impact testing with different size projectiles at various impact energies as the reference alloy and subsequently fatigue tested. Impacting degraded the residual fatigue life. However, under the ballistic impact conditions studied, it was concluded that the impacts expected in an aeroengine would not result in catastrophic damage, nor would the damage be severe enough to result in a fatigue failure under the anticipated design loads. In addition, other gamma alloys were investigated including another cast-to-size alloy, several cast and machined specimens, and a forged alloy. Within this Ti-48-2-2 family of alloys aluminum content was also varied. The cracking patterns as a result of impacting were documented and correlated with impact variables. The cracking type and severity was reasonably predicted using finite element models. Mean stress affects were also studied on impact-damaged fatigue samples. The fatigue strength was accurately predicted based on the flaw size using a threshold-based, fracture mechanics approach. To study the effects of wear due to potential applications in a blade-disk dovetail arrangement, the machined Ti-47-2-2 alloy was fretted against In-718 using pin-on-disk experiments. Wear mechanisms were documented and compared to those of Ti-6Al-4V. A few fatigue samples were also fretted and subsequently fatigue tested. It was found that under the conditions studied, the fretting was not severe enough to affect the fatigue strength of g-TiAl.

  16. A new measurement of the rare decay eta -> pi^0 gamma gamma with the Crystal Ball/TAPS detectors at the Mainz Microtron

    Energy Technology Data Exchange (ETDEWEB)

    Nefkens, B M; Prakhov, S; Aguar-Bartolom��, P; Annand, J R; Arends, H J; Bantawa, K; Beck, R; Bekrenev, V; Bergh��user, H; Braghieri, A; Briscoe, W J; Brudvik, J; Cherepnya, S; Codling, R F; Collicott, C; Costanza, S; Danilkin, I V; Denig, A; Demissie, B; Dieterle, M; Downie, E J; Drexler, P; Fil' kov, L V; Fix, A; Garni, S; Glazier, D I; Gregor, R; Hamilton, D; Heid, E; Hornidge, D; Howdle, D; Jahn, O; Jude, T C; Kashevarov, V L; K��ser, A; Keshelashvili, I; Kondratiev, R; Korolija, M; Kotulla, M; Koulbardis, A; Kruglov, S; Krusche, B; Lisin, V; Livingston, K; MacGregor, I J; Maghrbi, Y; Mancel, J; Manley, D M; McNicoll, E F; Mekterovic, D; Metag, V; Mushkarenkov, A; Nikolaev, A; Novotny, R; Oberle, M; Ortega, H; Ostrick, M; Ott, P; Otte, P B; Oussena, B; Pedroni, P; Polonski, A; Robinson, J; Rosner, G; Rostomyan, T; Schumann, S; Sikora, M H; Starostin, A; Strakovsky, I I; Strub, T; Suarez, I M; Supek, I; Tarbert, C M; Thiel, M; Thomas, A; Unverzagt, M; Watts, D P; Werthmueller, D; Witthauer, L

    2014-08-01

    A new measurement of the rare, doubly radiative decay eta->pi^0 gamma gamma was conducted with the Crystal Ball and TAPS multiphoton spectrometers together with the photon tagging facility at the Mainz Microtron MAMI. New data on the dependence of the partial decay width, Gamma(eta->pi^0 gamma gamma), on the two-photon invariant mass squared, m^2(gamma gamma), as well as a new, more precise value for the decay width, Gamma(eta->pi^0 gamma gamma) = (0.33+/-0.03_tot) eV, are based on analysis of 1.2 x 10^3 eta->pi^0 gamma gamma decays from a total of 6 x 10^7 eta mesons produced in the gamma p -> eta p reaction. The present results for dGamma(eta->pi^0 gamma gamma)/dm^2(gamma gamma) are in good agreement with previous measurements and recent theoretical calculations for this dependence.

  17. Search for the decays $J/\\psi\\to\\gamma \\rho \\phi$ and $J/\\psi\\to\\gamma \\rho \\omega$

    CERN Document Server

    Bai, J Z; Cai, X; Chen, H F; Chen, H S; Chen, H X; Chen, J C; Chen, Jin; Chen, Y B; Chu, Y P; Dai, Y S; Diao, L Y; Deng, Z Y; Dong, Q F; Du, S X; Fang, J; Fang, S S; Fu, C D; Gao, C S; Gao, Y N; Gu, S D; Gu, Y T; Guo, Y N; Guo, Z J; Harris, F A; He, K L; He, M; Heng, Y K; Hou, J; Hu, H M; Hu, J H; Hu, T; Huang, G S; Huang, X T; Ji, X B; Jiang, X S; Jiang, X Y; Jiao, J B; Jin, D P; Jin, S; Lai, Y F; Li, G; Li, H B; Li, J; Li, R Y; Li, S M; Li, W D; Li, W G; Li, X L; Li, X N; Li, X Q; Liang, Y F; Liao, H B; Liu, B J; Liu, C X; Liu, F; Fang Liu; Liu, H H; Liu, H M; Liu, J; Liu, J B; Liu, J P; Liu, Jian; Liu, Q; Liu, R G; Liu, Z A; Lou, Y C; Lu, F; Lu, G R; Lu, J G; Luo, C L; Ma, F C; Ma, H L; Ma, L L; Ma, Q M; Mao, Z P; Mo, X H; Nie, J; Olsen, S L; Ping, R G; Qi, N D; Qin, H; Qiu, J F; Ren, Z Y; Rong, G; Ruan, X D; Shan, L Y; Shang, L; Shen, C P; Shen, D L; Shen, X Y; Sheng, H Y; Sun, H S; Sun, S S; Sun, Y Z; Sun, Z J; Tang, X; Tong, G L; Varner, G S; Wang, D Y; Wang, L; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, Y F; Wang, Z; Wang, Z Y; Wang, Zheng; Wei, C L; Wei, D H; Weng, Y; Wu, N; Xia, X M; Xie, X X; Xu, G F; Xu, X P; Xu, Y; Yan, M L; Yang, H X; Yang, Y X; Ye, M H; Ye, Y X; Yu, G W; Yuan, C Z; Yuan, Y; Zang, S L; Zeng, Y; Zhang, B X; Zhang, B Y; Zhang, C C; Zhang, D H; Zhang, H Q; Zhang, H Y; Zhang, J W; Zhang, J Y; Zhang, S H; Zhang, X Y; Zhang, Yiyun; Zhang, Z X; Zhang, Z P; Zhao, D X; Zhao, J W; Zhao, M G; Zhao, P P; Zhao, W R; Zhao, Z G; Zheng, H Q; Zheng, J P; Zheng, Z P; Zhou, L; Zhu, K J; Zhu, Q M; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, B A; Zhuang, X A; Zou, B S

    2007-01-01

    Using 58 million $J/\\psi$ events collected with the Beijing Spectrometer (BESII) at the Beijing Electron-Positron Collider, the decays $J/\\psi\\to \\gamma\\phi\\rho$ and $J/\\psi\\to \\gamma\\omega\\rho$ are searched for, and upper limits on their branching fractions are reported at the 90% C. L. No clear structures are observed in the $\\gamma \\rho$, $\\gamma \\phi$, or $\\rho \\phi $ mass spectra for $J/\\psi\\to \\gamma\\phi\\rho$ nor in the $\\gamma \\rho$, $\\gamma \\omega$, or $\\rho \\omega$ mass spectra for $J/\\psi\\to \\gamma\\omega\\rho$.

  18. Comparison of gamma-gamma Phase Coarsening Responses of Three Powder Metal Disk Superalloys

    Science.gov (United States)

    Gabb, T. P.; Gayda, J.; Johnson, D. F.; MacKay, R. A.; Rogers, R. B.; Sudbrack, C. K.; Garg, A.; Locci, I. E.; Semiatin, S. L.; Kang, E.

    2016-01-01

    The phase microstructures of several powder metal (PM) disk superalloys were quantitatively evaluated. Contents, chemistries, and lattice parameters of gamma and gamma strengthening phase were determined for conventionally heat treated Alloy 10, LSHR, and ME3 superalloys, after electrolytic phase extractions. Several of long term heat treatments were then performed, to allow quantification of the precipitation, content, and size distribution of gamma at a long time interval to approximate equilibrium conditions. Additional coarsening heat treatments were performed at multiple temperatures and shorter time intervals, to allow quantification of the precipitation, contents and size distributions of gamma at conditions diverging from equilibrium. Modest differences in gamma and gamma lattice parameters and their mismatch were observed among the alloys, which varied with heat treatment. Yet, gamma coarsening rates were very similar for all three alloys in the heat treatment conditions examined. Alloy 10 had higher gamma dissolution and formation temperatures than LSHR and ME3, but a lower lattice mismatch, which was slightly positive for all three alloys at room temperature. The gamma precipitates of Alloy 10 appeared to remain coherent at higher temperatures than for LSHR and ME3. Higher coarsening rates were observed for gamma precipitates residing along grain boundaries than for those within grains in all three alloys, during slow-moderate quenching from supersolvus solution heat treatments, and during aging at temperatures of 843 C and higher.

  19. A separation of electrons and protons in the GAMMA-400 gamma-ray telescope

    CERN Document Server

    Leonov, A A; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Cumani, P; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    The GAMMA-400 gamma-ray telescope is intended to measure the fluxes of gamma rays and cosmic-ray electrons and positrons in the energy range from 100 MeV to several TeV. Such measurements concern with the following scientific goals: search for signatures of dark matter, investigation of gamma-ray point and extended sources, studies of the energy spectra of Galactic and extragalactic diffuse emission, studies of gamma-ray bursts and gamma-ray emission from the active Sun, as well as high-precision measurements of spectra of high-energy electrons and positrons, protons, and nuclei up to the knee. The main components of cosmic rays are protons and helium nuclei, whereas the part of lepton component in the total flux is ~10E-3 for high energies. In present paper, the capability of the GAMMA-400 gamma-ray telescope to distinguish electrons and positrons from protons in cosmic rays is investigated. The individual contribution to the proton rejection is studied for each detector system of the GAMMA-400 gamma-ray tel...

  20. Human gamma oscillations during slow wave sleep.

    Directory of Open Access Journals (Sweden)

    Mario Valderrama

    Full Text Available Neocortical local field potentials have shown that gamma oscillations occur spontaneously during slow-wave sleep (SWS. At the macroscopic EEG level in the human brain, no evidences were reported so far. In this study, by using simultaneous scalp and intracranial EEG recordings in 20 epileptic subjects, we examined gamma oscillations in cerebral cortex during SWS. We report that gamma oscillations in low (30-50 Hz and high (60-120 Hz frequency bands recurrently emerged in all investigated regions and their amplitudes coincided with specific phases of the cortical slow wave. In most of the cases, multiple oscillatory bursts in different frequency bands from 30 to 120 Hz were correlated with positive peaks of scalp slow waves ("IN-phase" pattern, confirming previous animal findings. In addition, we report another gamma pattern that appears preferentially during the negative phase of the slow wave ("ANTI-phase" pattern. This new pattern presented dominant peaks in the high gamma range and was preferentially expressed in the temporal cortex. Finally, we found that the spatial coherence between cortical sites exhibiting gamma activities was local and fell off quickly when computed between distant sites. Overall, these results provide the first human evidences that gamma oscillations can be observed in macroscopic EEG recordings during sleep. They support the concept that these high-frequency activities might be associated with phasic increases of neural activity during slow oscillations. Such patterned activity in the sleeping brain could play a role in off-line processing of cortical networks.

  1. Modeling gamma-ray bursts

    Science.gov (United States)

    Maxham, Amanda

    Discovered serendipitously in the late 1960s, gamma-ray bursts (GRBs) are huge explosions of energy that happen at cosmological distances. They provide a grand physical playground to those who study them, from relativistic effects such as beaming, jets, shocks and blastwaves to radiation mechanisms such as synchrotron radiation to galatic and stellar populations and history. Through the Swift and Fermi space telescopes dedicated to observing GRBs over a wide range of energies (from keV to GeV), combined with accurate pinpointing that allows ground based follow-up observations in the optical, infrared and radio, a rich tapestry of GRB observations has emerged. The general picture is of a mysterious central engine (CE) probably composed of a black hole or neutron star that ejects relativistic shells of matter into intense magnetic fields. These shells collide and combine, releasing energy in "internal shocks" accounting for the prompt emission and flaring we see and the "external shock" or plowing of the first blastwave into the ambient surrounding medium has well-explained the afterglow radiation. We have developed a shell model code to address the question of how X-ray flares are produced within the framework of the internal shock model. The shell model creates randomized GRB explosions from a central engine with multiple shells and follows those shells as they collide, merge and spread, producing prompt emission and X-ray flares. We have also included a blastwave model, which can constrain X-ray flares and explain the origin of high energy (GeV) emission seen by the Fermi telescope. Evidence suggests that gamma-ray prompt emission and X-ray flares share a common origin and that at least some flares can only be explained by long-lasting central engine activity. We pay special attention to the time history of central engine activity, internal shocks, and observed flares. We calculate the gamma-ray (Swift/BAT band) and X-ray (Swift/XRT band) lightcurves for arbitrary

  2. The propagation of gamma quanta in matter

    CERN Document Server

    Lejpunskij, Ovsej Ilich; Sakharov, Vsevolod Nikolaevich

    1965-01-01

    The Propagation of Gamma Quanta in Matter deals with various problems of the propagation and absorption of gamma quanta in matter, particularly the occurrence of multiple scattering of radiation. The ultimate objective is to determine the material, size, and configuration that will ensure the safe absorption of nuclear radiation. Shield design problems are given, the solution of which is achieved using numerical data presented in graphs and tables. This volume is comprised of three chapters and begins with an overview of the interaction of gamma radiation with matter and multiple scattering of

  3. GAMMA-KNIFE: OPERATION OHNE SKALPELL

    OpenAIRE

    АБЛЯЕВА В.И.; НИКОЛАЕВА Н.А.; ДЕНИСОВА О.С.

    2015-01-01

    Das Gamma-Knife ist ein Operationsroboter, mit dem Ärzte durch Photonenstrahlen im Körper operieren können. Die Photonen beschädigen die DNA von Zellen, so dass diese sich nicht mehr teilen können. Gutartige Tumoren vernarben in den Wochen und Monaten nach der Behandlung, bösartige zerfallen. Mit dem Gamma-Knife können unterschiedliche Arten von Tumoren behandelt werden, gutartige ebenso wie bösartige. Zu den Diagnosen, bei denen das Gamma-Knife in Frage kommt, gehören zum Beispiel Akustikusn...

  4. Atmospheric Cherenkov Gamma-ray Telescopes

    CERN Document Server

    Holder, Jamie

    2015-01-01

    The stereoscopic imaging atmospheric Cherenkov technique, developed in the 1980s and 1990s, is now used by a number of existing and planned gamma-ray observatories around the world. It provides the most sensitive view of the very high energy gamma-ray sky (above 30 GeV), coupled with relatively good angular and spectral resolution over a wide field-of-view. This Chapter summarizes the details of the technique, including descriptions of the telescope optical systems and cameras, as well as the most common approaches to data analysis and gamma-ray reconstruction.

  5. Dipole strength in 144Sm studied via (gamma,n), (gamma,p) and (gamma,alpha) reactions

    CERN Document Server

    Nair, Chithra; Erhard, Martin; Bemmerer, Daniel; Beyer, Roland; Grosse, Eckart; Kosev, Krasimir; Marta, Michele; Rusev, Gencho; Schilling, Klaus-Dieter; Schwengner, Ronald; Wagner, Andreas

    2010-01-01

    Photoactivation measurements on 144Sm have been performed with bremsstrahlung endpoint energies from 10.0 to 15.5 MeV at the bremsstrahlung facility of the superconducting electron accelerator ELBE of Forschungszentrum Dresden-Rossendorf. The measured activation yield for the 144Sm(gamma,n) reaction is compared with the calculated yield using cross sections from previous photoneutron experiments. The activation yields measured for all disintegration channels 144Sm(gamma,n), (gamma,p) and (gamma,alpha) are compared to the yield calculated by using Hauser-Feshbach statistical models. A new parametrization of the photon strength function is presented and the yield simulated by using the modified photon strength parameters are compared to the experimental data.

  6. A Search for the Rare Decay $B\\rightarrow\\gamma\\gamma$

    Energy Technology Data Exchange (ETDEWEB)

    del Amo Sanchez, P.; Lees, J.P.; Poireau, V.; Prencipe, E.; Tisserand, V.; /Annecy, LAPP; Garra Tico, J.; Grauges, E.; /Barcelona U., ECM; Martinelli, M.; Palano, A.; Pappagallo, M.; /INFN, Bari /Bari U.; Eigen, G.; Stugu, B.; Sun, L.; /Bergen U.; Battaglia, M.; Brown, D.N.; Hooberman, B.; Kerth, L.T.; Kolomensky, Yu.G.; Lynch, G.; Osipenkov, I.L.; Tanabe, T.; /UC, Berkeley /Birmingham U. /Ruhr U., Bochum /British Columbia U. /Brunel U. /Novosibirsk, IYF /UC, Irvine /UC, Riverside /UC, Santa Barbara /UC, Santa Cruz /Caltech /Cincinnati U. /Colorado U. /Colorado State U. /Dortmund U. /Dresden, Tech. U. /Ecole Polytechnique /Edinburgh U. /INFN, Ferrara /Ferrara U. /INFN, Ferrara /INFN, Ferrara /Ferrara U. /INFN, Ferrara /Frascati /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /Indian Inst. Tech., Guwahati /Harvard U. /Heidelberg U. /Humboldt U., Berlin /Imperial Coll., London /Iowa State U. /Iowa State U. /Johns Hopkins U. /Orsay, LAL /LLNL, Livermore /Liverpool U. /Queen Mary, U. of London /Royal Holloway, U. of London /Royal Holloway, U. of London /Louisville U. /Mainz U., Inst. Kernphys. /Manchester U. /Maryland U. /Massachusetts U., Amherst /MIT /McGill U. /INFN, Milan /Milan U. /INFN, Milan /INFN, Milan /Milan U. /Mississippi U. /Montreal U. /INFN, Naples /Naples U. /NIKHEF, Amsterdam /NIKHEF, Amsterdam /Notre Dame U. /Ohio State U. /Oregon U. /INFN, Padua /Padua U. /INFN, Padua /INFN, Padua /Padua U. /Paris U., VI-VII /INFN, Perugia /Perugia U. /INFN, Pisa /Pisa U. /INFN, Pisa /Pisa, Scuola Normale Superiore /INFN, Pisa /Pisa U. /INFN, Pisa /Princeton U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /Rostock U. /Rutherford /DAPNIA, Saclay /SLAC /South Carolina U. /Southern Methodist U. /Stanford U., Phys. Dept. /SUNY, Albany /Tel Aviv U. /Tennessee U. /Texas Nuclear Corp., Austin /Texas U., Dallas /INFN, Turin /Turin U. /INFN, Trieste /Trieste U. /Valencia U. /Victoria U. /Warwick U. /Wisconsin U., Madison

    2011-06-02

    We report the result of a search for the rare decay B{sup 0} {yields} {gamma}{gamma} in 426 fb{sup -1} of data, corresponding to 226 million B{sup 0}{bar B}{sup 0} pairs, collected on the {Upsilon}(4S) resonance at the PEP-II asymmetric-energy e{sup +}e{sup -} collider using the BABAR detector. We use a maximum likelihood fit to extract the signal yield and observe 21{sub -12}{sup +13} signal events with a statistical signficance of 1.9 {sigma}. This corresponds to a branching fraction {Beta}(B{sup 0} {yields} {gamma}{gamma}) = (1.7 {+-} 1.1(stat.) {+-} 0.2(syst.)) x 10{sup -7}. Based on this result, we set a 90% confidence level upper limit of {Beta}(B{sup 0} {yields} {gamma}{gamma}) < 3.2 x 10{sup -7}.

  7. Coupling WW, ZZ unitarized amplitudes to $\\gamma\\gamma$ in the TeV region

    CERN Document Server

    Delgado, Rafael L; Llanes-Estrada, Felipe J

    2016-01-01

    We define and calculate helicity partial-wave amplitudes for processes linking the Electroweak Symmetry Breaking Sector (EWSBS) to $\\gamma\\gamma$, employing (to NLO) the Higgs-EFT (HEFT) extension of the Standard Model and the Equivalence Theorem, while neglecting all particle masses. The resulting amplitudes can be useful in the energy regime ($500\\,{\\rm GeV}-3\\,{\\rm TeV}$). We also deal with their unitarization so that resonances of the EWSBS can simultaneously be described in the $\\gamma\\gamma$ initial or final states. Our resulting amplitudes satisfy unitarity, perturbatively in $\\alpha$, but for all $s$ values. In this way we improve on the HEFT that fails as interactions become stronger with growing $s$ and provide a natural framework for the decay of dynamically generated resonances into $WW$, $ZZ$ and $\\gamma\\gamma$ pairs.

  8. GAMMA-RAY AND X-RAY EMISSION FROM GAMMA-RAY-LOUD BLAZARS

    Institute of Scientific and Technical Information of China (English)

    ZHANG XIONG; ZHAO GANG; XIE GUANG-ZHONG; ZHENG GUANG-SHENG; ZHANG LI

    2001-01-01

    We present a strong correlation of the gamma-ray (above 100 MeV) mean spectral indices aγ and X-ray (1 keV)mean spectral indices cX for 34 gamma-ray-loud blazars (16 BL Lac objects and 18 flat spectrum radio quasars). Astrong correlation is also found between the gamma-ray flux densities F-γ and X-ray flux densities Fx in the low state for 47 blazars (17 BL Lac and 30 flat spectrum radio quasars). Possible correlation on the gamma-ray emission mechanism is discussed. We suggest that the main gamma-ray radiation mechanism is probably the synchrotron process. The gamma-ray emission may be somewhat different from that of BL Lac objects and flat spectrum radio quasars.

  9. Renormalization of dimension-six operators relevant for the Higgs decays $h\\rightarrow \\gamma\\gamma,\\gamma Z$

    CERN Document Server

    Elias-Miró, J; Masso, E; Pomarol, A

    2013-01-01

    The discovery of the Higgs boson has opened a new window to test the SM through the measurements of its couplings. Of particular interest is the measured Higgs coupling to photons which arises in the SM at the one-loop level, and can then be significantly affected by new physics. We calculate the one-loop renormalization of the dimension-six operators relevant for $h\\rightarrow \\gamma\\gamma, \\gamma Z$, which can be potentially important since it could, in principle, give log-enhanced contributions from operator mixing. We find however that there is no mixing from any current-current operator that could lead to this log-enhanced effect. We show how the right choice of operator basis can make this calculation simple. We then conclude that $h\\rightarrow \\gamma\\gamma, \\gamma Z$ can only be affected by RG mixing from operators whose Wilson coefficients are expected to be of one-loop size, among them fermion dipole-moment operators which we have also included.

  10. Measurement of \\Gamma(\\eta -> \\pi^+\\pi^-\\gamma)/\\Gamma(\\eta -> \\pi^+\\pi^-\\pi^0) with the KLOE Detector

    CERN Document Server

    Babusci, D; Balwierz-Pytko, I; Bencivenni, G; Bini, C; Bloise, C; Bocci, V; Bossi, F; Branchini, P; Budano, A; Caldeira Balkest, L; Capon, G; Ceradini, F; Ciambrone, P; Czerwinski, E; Dane, E; De Lucia, E; De Robertis, G; De Santis, A; De Simone, P; Di Domenico, A; Di Donato, C; Di Micco, B; Di Salvo, R; Domenici, D; Erriquez, O; Fanizzi, G; Fantini, A; Felici, G; Fiore, S; Franzini, P; Gauzzi, P; Giardina, G; Giovannella, S; Gonnella, F; Graziani, E; Happacher, F; Hoistad, B; Iafolla, L; Jacewicz, M; Johansson, T; Kupsc, A; Lee-Franzini, J; Leverington, B; Loddo, F; Loffredo, S; Mandaglio, G; Martemianov, M; Martini, M; Mascolo, M; Messi, R; Miscetti, S; Morello, G; Moricciani, D; Moskal, P; Nguyen, F; Passeri, A; Patera, V; Prado Longhi, I; Ranieri, A; Redmer, C.F; Santangelo, P; Sarra, I; Schioppa, M; Sciascia, B; Silarski, M; Taccini, C; Tortora, L; Venanzoni, G; Versaci, R; Wislicki, W; Wolke, M; Xu, G; Zdebik, J

    2013-01-01

    The ratio R_{\\eta}=\\Gamma(\\eta -> \\pi^+\\pi^-\\gamma)/\\Gamma(\\eta -> \\pi^+\\pi^-\\pi^0) has been measured by analyzing 22 million \\phi \\to \\eta \\gamma decays collected by the KLOE experiment at DA\\PhiNE, corresponding to an integrated luminosity of 558 pb^{-1}. The \\eta \\to \\pi^+\\pi^-\\gamma proceeds both via the \\rho resonant contribution, and possibly a non-resonant direct term, connected to the box anomaly. Our result, R_{\\eta}= 0.1856\\pm 0.0005_{stat} \\pm 0.0028_{syst}, points out a sizable contribution of the direct term to the total width. The di-pion invariant mass for the \\eta -> \\pi^+\\pi^-\\gamma decay could be described in a model-independent approach in terms of a single free parameter, \\alpha. The determined value of the parameter \\alpha is \\alpha = (1.32 \\pm 0.08_{stat} +0.10/-0.09_{syst}\\pm 0.02_{theo}) GeV^{-2}

  11. Tests of quantum chromodynamics in exclusive e sup + e sup minus and. gamma. gamma. processes

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, S.J.

    1989-09-01

    This paper discusses the following topics: Factorization theorem for exclusive processes; Electromagnetic form factors of baryons; Suppression of final state interactions; The {gamma}{pi}{sub 0} Transition form factor; Exclusive charmonium decays; The {pi}-{rho} puzzle; Time-like compton processes; Multi-hadron production; Heavy Quark exclusive states and form factor zeros in QCD; Exclusive {gamma}{gamma} reactions; Higher twist effects; and Tauonium and threshold {tau}{sup +}{tau}{sup {minus}} production. 41 refs., 15 figs. (LSP)

  12. HotSpotter? Neutron/Gamma Detector

    Energy Technology Data Exchange (ETDEWEB)

    Bell, Z.W.

    2003-04-01

    The HotSpotter{trademark} Neutron/Gamma Detector combines in a single detecting module high sensitivity to gamma rays up to 3 MeV and sensitivity to neutrons. Using a 15 mm cubic CdWO{sub 4} (cadmium tungstate) crystal mounted on a 25 mm photomultiplier, the instrument realizes a factor of 5 increased photopeak efficiency over NaI(Tl) at 1 MeV, and a factor of 2 improvement over CsI(Tl). The addition of a 0.5 mm layer of {sup 10}B- impregnated epoxy covering the crystal provides neutron sensitivity without sacrificing gamma ray spectroscopic characteristics. Neutrons are detected by the presence of the 478 keV gamma from the {sup 10}B(n,{alpha}){sup 7}Li* reaction. In this paper, we describe the electronics and software of the instrument, and some of its characteristics.

  13. Supernova remnants and gamma-ray sources

    CERN Document Server

    Torres, D F; Dame, T M; Combi, J A; Butt, Y M; Torres, Diego F.; Romero, Gustavo E.; Dame, Thomas M.; Combi, Jorge A.; Butt, Yousaf M.

    2003-01-01

    A review of the possible relationship between $\\gamma$-ray sources and supernova remnants (SNRs) is presented. Particular emphasis is given to the analysis of the observational status of the problem of cosmic ray acceleration at SNR shock fronts. All positional coincidences between SNRs and unidentified $\\gamma$-ray sources listed in the Third EGRET Catalog at low Galactic latitudes are discussed on a case by case basis. For several coincidences of particular interest, new CO(J=1-0) and radio continuum maps are shown, and the mass content of the SNR surroundings is determined. The contribution to the $\\gamma$-ray flux observed that might come from cosmic ray particles (particularly nuclei) locally accelerated at the SNR shock fronts is evaluated. We discuss the prospects for future research in this field and remark on the possibilities for observations with forthcoming $\\gamma$-ray instruments.

  14. Stable homotopical algebra and [Gamma]-spaces

    Science.gov (United States)

    Schwede, Stefan

    1999-03-01

    In this paper we advertise the category of [Gamma]-spaces as a convenient framework for doing ‘algebra’ over ‘rings’ in stable homotopy theory. [Gamma]-spaces were introduced by Segal [Se] who showed that they give rise to a homotopy category equivalent to the usual homotopy category of connective (i.e. ([minus sign]1)-connected) spectra. Bousfield and Friedlander [BF] later provided model category structures for [Gamma]-spaces. The study of ‘rings, modules and algebras’ based on [Gamma]-spaces became possible when Lydakis [Ly] introduced a symmetric monoidal smash product with good homotopical properties. Here we develop model category structures for modules and algebras, set up (derived) smash products and associated spectral sequences and compare simplicial modules and algebras to their Eilenberg-MacLane spectra counterparts.

  15. The $e^+ e^- \\to Z\\gamma\\gamma \\to q\\overline{q}\\gamma\\gamma$ Reaction at LEP and Constraints on Anomalous Quartic Gauge Boson Couplings

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, Michael; Doria, A; Dova, M T; Duchesneau, D; Echenard, B; Eline, A; El-Mamouni, H; Engler, A; Eppling, F J; Ewers, A; Extermann, Pierre; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hakobyan, R S; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Latt, J; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Palomares, C; Pandoulas, D; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R P; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wallraff, W; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2002-01-01

    The cross section of the process e^+ e^- -> Z \\gamma\\gamma -> qq~ \\gamma \\gamma is measured with 215 pb^-1 of data collected with the L3 detector during the final LEP run at centre-of-mass energies around 205 GeV and 207 GeV. No deviation from the Standard Model expectation is observed. The full data sample of 713 pb^-1, collected above the Z resonance, is used to constrain the coefficients of anomalous quartic gauge boson couplings to: -0.02 GeV^-2 < a_0/\\Lambda^2 < 0.03 GeV^-2 and -0.07 GeV^-2 < a_c/\\Lambda^2 < 0.05 GeV^-2, at 95% confidence level.

  16. Project Marna Natural Gamma Radiation MAP

    International Nuclear Information System (INIS)

    The confusion created by the accident that occurred in one of the Chernobyl reactors in April of 1986 made the general public and governments aware of the need for improved monitoring of environmental radiation levels. The levels of total gamma radiation or total gamma exposure rate over large areas reached values as high as 400 micro Roentgen/hour (mu R/h) and at points exceeded 1000 mu R/h. It should be borne in mind that, depending on the type of geological formations, normal values range from 5 to 30 mu R/h. The IAEA recommended to all countries that natural gamma radiation maps be made available to evaluate the levels of natural gamma radiation and possible increases, and it also indicated its concern that information be standardized. In addition, it stressed the advisability of using data obtained from uranium prospecting. (Author)

  17. Gamma knife radiosurgery for cerebral arteriovenous malformations.

    Science.gov (United States)

    Kemeny, A A; Radatz, M W R; Rowe, J G; Walton, L; Hampshire, A

    2004-01-01

    Since its introduction, gamma knife radiosurgery has become an important treatment modality for cerebral arteriovenous malformations. This paper is a brief overview of the technique used, of the clinical results achieved and of the experience gained in Sheffield.

  18. Gamma-Ray Astrophysics NSSTC Fermi GBM

    Data.gov (United States)

    National Aeronautics and Space Administration — The Fermi Gamma-Ray Burst Monitor (GBM) is not a pointed or imaging instrument. To determine fluxes for known sources, we measure the change in the count rate...

  19. Gamma beam system at ELI-NP

    Energy Technology Data Exchange (ETDEWEB)

    Ur, Calin Alexandru, E-mail: calin.ur@eli-np.ro [Extreme Light Infrastructure, IFIN-HH, Magurele-Bucharest (Romania)

    2015-02-24

    The Gamma Beam System of ELI-NP will produce brilliant, quasi-monochromatic gamma-ray beams via Inverse Compton Scattering of short laser pulses on relativistic electron beam pulses. The scattered radiation is Doppler upshifted by more than 1,000,000 times and is forward focused in a narrow, polarized, tunable, laser-like beam. The gamma-ray beam at ELI-NP will be characterized by large spectral density of about 10{sup 4} photons/s/eV, narrow bandwidth (< 0.5%) and tunable energy from 200 keV up to about 20 MeV. The Gamma Beam System is a state-of-the-art equipment employing techniques and technologies at the limits of the present-day's knowledge.

  20. Monochromatic gamma emitter for low energy quanta

    CERN Document Server

    Tomova, Z R; Mironova, S A

    2004-01-01

    The possibility of creating of a monochromatic gamma emitter of low energy quanta is analyzed. The idea is based on Daning's scheme. Except for purely scientific problems the monochromator is actual for therapy of wide range of diseases.

  1. Precision measurements of gamma-ray intensities

    International Nuclear Information System (INIS)

    To determine relative intensities of gamma rays in the region of 280 to 2750 keV, Ge(Li) detectors were calibrated with standard sources and cascade gamma-ray sources. Decay rates of the standard sources were determined by means of the 4πβ-γ or 4πX-γ coincidence method. Experimental conditions were improved and spectra were carefully analyzed. Relative gamma-ray intensities of 56Co, 88Y, sup(110m)Ag, 133Ba, 134Cs, 152Eu, 154Eu, 192Ir and 207Bi were determined within the accuracy of about 0.5% for strong gamma rays. Intensities per decays were obtained from the relative intensities for most of the nuclides. (author)

  2. Review of Ge detectors for gamma spectroscopy

    CERN Document Server

    Alexiev, D; Mo, L; Smith, M L; Rosenfeld, A H

    2002-01-01

    A review is given of the use of germanium detectors for gamma spectroscopy. The advantages, principles of operation, and fabrication processes of semiconductor radiation detectors are described. Copyright (2002) Australasian College of Physical Scientists and Engineers in Medicine

  3. Bound-state effects in $\\mu^{+}e^{-} \\to \\gamma\\gamma$ and $\\overline{B}^{0}_{s} \\to \\gamma\\gamma$ decays

    CERN Document Server

    Eeg, Jan O; Picek, I

    2000-01-01

    We demonstrate that in the double-radiative decays of heavy-light QED and QCD atoms, \\mu^{+} e^{-} \\to \\gamma\\gamma and \\bar{B}^{0}_{s} \\to \\gamma\\gamma, there is a contribution coming from operators that vanish on the free-quark mass shell. This off-shell effect is suppressed with respect to the effect of the well known flavour-changing magnetic-moment operator by the bound-state binding factor. Accordingly, the negligible off-shellness of the weakly bound QED atoms becomes important for strongly bound QCD atoms. We present this effect in two different model-approaches to QCD, one of them enabling us to keep close contact to the related effect in QED.

  4. A localized excess of diffuse gamma radiation

    Science.gov (United States)

    Chen, A.; Dwyer, J.; Kaaret, P.

    1995-01-01

    Using archival Energetic Gamma Ray Experiment Telescope (EGRET) gamma-ray data and atomic hydrogen (H I) column densities derived from 21 cm radio observations, we have found a large irregular region in the northern Galactic hemisphere extending from (l approximately 90 deg, b approximately 52 deg) to (l approximately 45 deg, b approximately 77 deg) with a significant enhancement in the gamma-ray emissivity compared to the surrounding sky. The region contains no previously identified gamma-ray point sources. The emission may arise from a localized enhancement in cosmic-ray density or from the presence of matter other than H I. If the emission is due to unseen matter, a column density enhancement equivalent to approximately 2 x 10(exp 20) H-atoms/sq cm is required.

  5. The HAWC Gamma-Ray Observatory: Sensitivity to Steady and Transient Sources of Gamma Rays

    CERN Document Server

    Abeysekara, A U; Alvarez, C; Álvarez, J D; Arceo, R; Arteaga-Velázquez, J C; Solares, H A Ayala; Barber, A S; Baughman, B M; Bautista-Elivar, N; Belmont, E; BenZvi, S Y; Berley, D; Rosales, M Bonilla; Braun, J; Caballero-Lopez, R A; Caballero-Mora, K S; Carramiñana, A; Castillo, M; Cotti, U; Cotzomi, J; de la Fuente, E; De León, C; DeYoung, T; Hernandez, R Diaz; Díaz-Vélez, J C; Dingus, B L; DuVernois, M A; Ellsworth, R W; Fernandez, A; Fiorino, D W; Fraija, N; Galindo, A; Garfias, F; González, L X; González, M M; Goodman, J A; Grabski, V; Gussert, M; Hampel-Arias, Z; Hui, C M; Hüntemeyer, P; Imran, A; Iriarte, A; Karn, P; Kieda, D; Kunde, G J; Lara, A; Lauer, R J; Lee, W H; Lennarz, D; Vargas, H León; Linares, E C; Linnemann, J T; Longo, M; Luna-GarcIa, R; Marinelli, A; Martinez, H; Martinez, O; Martínez-Castro, J; Matthews, J A J; Miranda-Romagnoli, P; Moreno, E; Mostafá, M; Nava, J; Nellen, L; Newbold, M; Noriega-Papaqui, R; Oceguera-Becerra, T; Patricelli, B; Pelayo, R; Pérez-Pérez, E G; Pretz, J; Rivière, C; Rosa-González, D; Salazar, H; Salesa, F; Sanchez, F E; Sandoval, A; Santos, E; Schneider, M; Silich, S; Sinnis, G; Smith, A J; Sparks, K; Springer, R W; Taboada, I; Toale, P A; Tollefson, K; Torres, I; Ukwatta, T N; Villaseñor, L; Weisgarber, T; Westerhoff, S; Wisher, I G; Wood, J; Yodh, G B; Younk, P W; Zaborov, D; Zepeda, A; Zhou, H

    2013-01-01

    The High-Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory is designed to record air showers produced by cosmic rays and gamma rays between 100 GeV and 100 TeV. Because of its large field of view and high livetime, HAWC is well-suited to measure gamma rays from extended sources, diffuse emission, and transient sources. We describe the sensitivity of HAWC to emission from the extended Cygnus region as well as other types of galactic diffuse emission; searches for flares from gamma-ray bursts and active galactic nuclei; and the first measurement of the Crab Nebula with HAWC-30.

  6. Measurement of the Charm Production Cross Section in gamma gamma Collisions at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Todorova-Nová, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ewers, A; Extermann, Pierre; Fabre, M; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, M; Wang, X L; Wang, Z M; Weber, A; Weber, M; Wienemann, P; Wilkens, H; Wu, S X; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Ye, J B; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhu, G Y; Zhu, R Y; Zichichi, A; Zilizi, G; Zimmermann, B; Zöller, M

    2001-01-01

    Open charm production in gamma-gamma collisions is studied with data collected at e+e- centre-of-mass energies from 189 GeV to 202 GeV corresponding to a total integrated luminosity of 410 pb-1. The charm cross section sigma(gamma gamma ---> c c~ X) is measured for the first time as a function of the two-photon centre-of-mass energy in the interval from 5 GeV to 70 GeV and is compared to NLO QCD calculations.

  7. Investigation of selected toxicological parameters of gamma-pentachlorocyclohexene (gamma-PCCH).

    Science.gov (United States)

    Mazzag, E; Nagymajtenyi, L; Huszta, E; Desi, I; Macholz, R

    1991-01-01

    The toxic effects of the gamma-hexachlorocyclohexane metabolite gamma-pentachlorocyclohexene (gamma-PCCH) were studied by acute and subacute (6 weeks) experiments. The investigations included cerebral convulsibility with chemoshock (Tetrazolium), reactivity with hot plate method, the learning ability with learning tests, and peripheral nervous activity (EMG). Nociceptive reaction time was not influenced, the learning process (6 weeks) was inhibited by gamma-PCCH. The conduction velocity of the peripheral nerve was decreased. At the end of the 6th week liver enlargement was found.

  8. Search for anomalous quartic $ZZ\\gamma\\gamma$ couplings in photon-photon collisions

    CERN Document Server

    Köksal, M; Senol, A

    2016-01-01

    The self-couplings of the electroweak gauge bosons are completely specified by the non-Abelian gauge nature of the Standard Model (SM). The direct study of these couplings provides a significant opportunity to test the validity of the SM and the existence of new physics beyond the SM up to the high energy scale. For this reason, we investigate the potential of the processes $\\gamma\\gamma\\rightarrow ZZ$, $e^{-}\\gamma\\rightarrow e^{-}\\gamma^{*}\\gamma \\rightarrow e^{-}Z\\, Z$ and $e^{+}e^{-}\\rightarrow e^{+}\\gamma^{*} \\gamma^{*} e^{-} \\rightarrow e^{+}\\, Z\\, Z\\, e^{-}$ to examine the anomalous quartic couplings of $ZZ\\gamma\\gamma$ vertex at the Compact Linear Collider (CLIC) with center-of-mass energies $0.35, 1.4$ and $3$ TeV. We calculate $95\\%$ confidence level sensitivities on the dimension-8 parameters with various values of the integrated luminosity. We show that the best bounds on the anomalous $\\frac{f_{M2}}{\\Lambda^{4}}$, $\\frac{f_{M3}}{\\Lambda^{4}}$, $\\frac{f_{T0}}{\\Lambda^4}$ and $\\frac{f_{T9}}{\\Lambda...

  9. The blazar gamma-ray luminosity function and the diffuse extragalactic gamma-ray background

    Science.gov (United States)

    Salamon, M. H.; Stecker, F. W.

    1994-01-01

    We have used the data from the new EGRET catalog on 'grazars' (blazers which are observed to be high-energy gamma-ray sources), together with radio data, to construct a new relation between radio and gamma-ray luminosity for these sources. Using this relation to construct a grazar gamma-ray luminosity function, we then calculate the contribution of unresolved grazars to the cosmic gamma-ray background radiation. We derive the energy spectrum of this background component above 100 MeV and the angular fluctuations in this background implied by our model.

  10. Single superparticle production via $\\gamma\\gamma$ collision with explicit R-parity violation

    CERN Document Server

    Chaichian, Masud; Yu, Z H

    2001-01-01

    We study the single production of scalar neutrinos or charginos via $\\gamma\\gamma$ collision in an R-parity ($R_{p}$) violating supersymmetric model. It may be possible to detect a sneutrino or a chargino at a Linear Collider (LC) in $\\gamma \\gamma$ operation mode, as a test of supersymmetry and $R_p$-violation. Because of the clean background in LC, stringent constraints on $R_p$ violating parameters can be obtained even if the process cannot be observed at the future Linear Collider.

  11. Search for the rare decay $D^0\\to\\gamma\\gamma$ at Belle

    CERN Document Server

    Nisar, N K; Trabelsi, K; Aziz, T; Abdesselam, A; Adachi, I; Aihara, H; Asner, D M; Aulchenko, V; Aushev, T; Ayad, R; Babu, V; Badhrees, I; Bahinipati, S; Barberio, E; Behera, P; Bhardwaj, V; Biswal, J; Bobrov, A; Bozek, A; Bračko, M; Breibeck, F; Browder, T E; Červenkov, D; Chekelian, V; Chen, A; Cheon, B G; Chistov, R; Cho, K; Chobanova, V; Choi, Y; Cinabro, D; Dalseno, J; Dash, N; Doležal, Z; Drásal, Z; Drutskoy, A; Dutta, D; Eidelman, S; Farhat, H; Fast, J E; Fulsom, B G; Gaur, V; Garmash, A; Gillard, R; Goh, Y M; Goldenzweig, P; Greenwald, D; Grzymkowska, O; Haba, J; Hara, T; Hayasaka, K; Hayashii, H; He, X H; Hou, W -S; Inami, K; Ishikawa, A; Iwasaki, Y; Jacobs, W W; Jaegle, I; Jeon, H B; Joffe, D; Joo, K K; Julius, T; Kang, K H; Kato, E; Kawasaki, T; Kiesling, C; Kim, D Y; Kim, H J; Kim, K T; Kim, M J; Kim, S H; Kinoshita, K; Kodyš, P; Korpar, S; Križan, P; Krokovny, P; Kuhr, T; Kumar, R; Kumita, T; Kuzmin, A; Kwon, Y -J; Lee, I S; Lange, J S; Li, H; Li, L; Gioi, L Li; Libby, J; Liventsev, D; Lukin, P; Masuda, M; Matvienko, D; Miyabayashi, K; Miyata, H; Mizuk, R; Mohanty, S; Moll, A; Moon, H K; Mori, T; Mussa, R; Nakano, E; Nakao, M; Nanut, T; Natkaniec, Z; Nayak, M; Niiyama, M; Nishida, S; Ogawa, S; Okuno, S; Pakhlov, P; Pakhlova, G; Pal, B; Park, C W; Park, H; Paul, S; Pedlar, T K; Pesántez, L; Pestotnik, R; Petrič, M; Piilonen, L E; Prasanth, K; Pulvermacher, C; Rauch, J; Ribežl, E; Ritter, M; Rostomyan, A; Ryu, S; Sahoo, H; Sandilya, S; Sanuki, T; Sato, Y; Savinov, V; Schlüter, T; Schneider, O; Schnell, G; Schwanda, C; Schwartz, A J; Seino, Y; Senyo, K; Seon, O; Seong, I S; Shebalin, V; Shibata, T -A; Shiu, J -G; Shwartz, B; Simon, F; Singh, J B; Sohn, Y -S; Solovieva, E; Stanič, S; Starič, M; Stypula, J; Sumihama, M; Sumiyoshi, T; Tamponi, U; Teramoto, Y; Uchida, M; Uglov, T; Uno, S; Urquijo, P; Van Hulse, C; Vanhoefer, P; Varner, G; Varvell, K E; Vinokurova, A; Vossen, A; Wagner, M N; Wang, C H; Wang, M -Z; Wang, X L; Watanabe, M; Watanabe, Y; Williams, K M; Won, E; Yelton, J; Yuan, C Z; Yusa, Y; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A

    2015-01-01

    We search for the rare radiative decay $D^0\\to\\gamma\\gamma$ using a data sample with an integrated luminosity of $832{\\rm fb^{-1}}$ recorded by the Belle detector at the KEKB $e^+e^-$ asymmetric-energy collider. We find no statistically significant signal and set an upper limit on the branching fraction of ${\\cal B}(D^0\\to\\gamma\\gamma)<8.5\\times10^{-7}$ at $90\\%$ confidence level. This is the most restrictive limit on the decay channel to date.

  12. RID-41 gamma flaw detector

    International Nuclear Information System (INIS)

    The design is described and the main characteristics are given of a universal stationary hose-type gamma flow detector with a 60Co source from 3O to 4g0 Ci for high-productive control of thick-walled products from steel and other materials. The principal units of the instrument are a radiation head, a control panel, and a charge-exchange container. The flaw detector may be used both in shield chambers and in shop or mounting conditions on complying with due requirements of radiation protection. The high activity of the source at relatively small dimensions of its active part ensures good detection of defects. The high radioscopy rate permits to use the flaw detector in conditions of increased background radiation, e.g. during routine repairs and inspections at nuclear power plants. The instrument may also be used in radiometric complexes, and produces a considerable economic effect. This flaw-detector corresponds to ISO and IAEA requirements and may be delivered for export

  13. How to treat $\\gamma_5$

    CERN Document Server

    Cheng, H; Cheng, Hung

    1996-01-01

    In this paper, we present a method to perform renormalized perturbation calculations to gauge theories with chiral fermions. We find it proper to focus directly on the Ward-Takahashi identities, relegating dimensional regularization into a supplementary and secondary role. We show with the example of the Abelian-Higgs theory how to handle amplitudes involving fermions, particularly how to handle the matrix $\\gamma_5$. As a demonstration of our method of renormalization, we evaluate the radiative corrections of the triangular anomaly in the Abelian-Higgs theory with chiral fermions and with Yukawa couplings. Families of chiral fermions with appropriate quantum numbers are introduced so that the sum of their contributions to the lowest-order anomaly is equal to zero. Both the left-handed and right-handed fermion of this theory are assumed to interact with the gauge field. We find that the anomaly amplitude in the next-lowest order is not zero, contrary to common belief. This anomaly amplitude is calculated with...

  14. Gamma-ray Burst Cosmology

    CERN Document Server

    Wang, F Y; Liang, E W

    2015-01-01

    Gamma-ray bursts (GRBs) are the most luminous electromagnetic explosions in the Universe, which emit up to $8.8\\times10^{54}$ erg isotropic equivalent energy in the hard X-ray band. The high luminosity makes them detectable out to the largest distances yet explored in the Universe. GRBs, as bright beacons in the deep Universe, would be the ideal tool to probe the properties of high-redshift universe: including the cosmic expansion and dark energy, star formation rate, the reionization epoch and the metal enrichment history of the Universe. In this article, we review the luminosity correlations of GRBs, and implications for constraining the cosmological parameters and dark energy. Observations show that the progenitors of long GRBs are massive stars. So it is expected that long GRBs are tracers of star formation rate. We also review the high-redshift star formation rate derived from GRBs, and implications for the cosmic reionization history. The afterglows of GRBs generally have broken power-law spectra, so it...

  15. Latest Results from VERITAS: Gamma 2016

    CERN Document Server

    Holder, J

    2016-01-01

    The VERITAS imaging atmospheric Cherenkov telescope array has been observing the northern TeV sky with four telescopes since summer 2007. Over 50 gamma-ray sources have been studied, including active and starburst galaxies, pulsars and their nebulae, supernova remnants and Galactic binary systems. We review here some of the most recent VERITAS results, and discuss the status and prospects for collaborative work with other gamma-ray instruments, and with multimessenger observatories.

  16. Track finding in gamma conversions in CMS

    OpenAIRE

    Marinelli, Nancy

    2007-01-01

    A track finding algorithm has been developed for reconstruction of e+e- pairs. It combines the information of the electromagnetic calorimeter with the information provided by the Tracker. Results on reconstruction efficiency of converted photons, as well as on fake rate are shown for single isolated photons and for photons from H->gamma gamma events with pile-up events at 10^33 cm^-2 s^-1 LHC luminosity.

  17. Supernovae and gamma-ray bursts connection

    Science.gov (United States)

    Valle, Massimo Della

    2015-12-01

    I'll review the status of the Supernova/Gamma-Ray Burst connection. Several pieces of evidence suggest that long duration Gamma-ray Bursts are associated with bright SNe-Ic. However recent works suggest that GRBs might be produced in tight binary systems composed of a massive carbon-oxygen cores and a neutron star companion. Current estimates of the SN and GRB rates yield a ratio GRB/SNe-Ibc in the range ˜ 0.4% - 3%.

  18. Gamma Oscillations Distinguish True From False Memories

    OpenAIRE

    Sederberg, Per B.; Schulze-Bonhage, Andreas; Madsen, Joseph R.; Bromfield, Edward B.; Litt, Brian; Brandt, Armin; Kahana, Michael J.

    2007-01-01

    To test whether distinct patterns of electrophysiological activity prior to a response can distinguish true from false memories, we analyzed intracranial electroencephalographic recordings while 52 patients undergoing treatment for epilepsy performed a verbal free-recall task. These analyses revealed that the same pattern of gamma-band (28–100 Hz) oscillatory activity that predicts successful memory formation at item encoding—increased gamma power in the hippocampus, prefrontal cortex, and le...

  19. Compton scattering gamma-ray source optimization

    Science.gov (United States)

    Hartemann, Frederic; Wu, Sheldon; Albert, Félicie; Barty, Chris

    2012-10-01

    The interaction of a bright relativistic electron beam with an intense laser pulse via Compton scattering can generate tunable gamma-rays for precision nuclear photonics applications. The properties of the gamma-ray phase space will be outlined, in relation with the 6D electron bunch and 6D laser pulse phase space, along with collimation, nonlinear effects and other sources of spectral broadening. Optimization strategies will be outlines within the context of nuclear photonics applications.

  20. Supernovae and gamma-ray bursts connection

    Energy Technology Data Exchange (ETDEWEB)

    Valle, Massimo Della [INAF-Napoli, Capodimonte Observatory, Salita Moiariello, 16, I-80131 Napoli (Italy); International Center for Relativistic Astrophysics Network, Piazzale della Repubblica 10, I-65122, Pescara (Italy)

    2015-12-17

    I’ll review the status of the Supernova/Gamma-Ray Burst connection. Several pieces of evidence suggest that long duration Gamma-ray Bursts are associated with bright SNe-Ic. However recent works suggest that GRBs might be produced in tight binary systems composed of a massive carbon-oxygen cores and a neutron star companion. Current estimates of the SN and GRB rates yield a ratio GRB/SNe-Ibc in the range ∼ 0.4% − 3%.

  1. New type air (automobile) gamma spectroscopic system

    International Nuclear Information System (INIS)

    A new type air (automobile) gamma spectroscopic system for identification and measuring of contamination with natural and artificial gamma isotopes is described. developed. Its main principle is a maximal use of the energy resolution of NaJ(Tl) detectors. The system consists of a spectrometer working simultaneously with a set of 1-16 scintillator blocks and a registration/ data processing unit. The operational mode, optimal performance and control subsystem are described

  2. Gamma-ray detected radio galaxies

    Science.gov (United States)

    Beckmann, Volker; Soldi, Simona; De Jong, Sandra; Kretschmer, Karsten; Savchenko, Volodymyr

    2016-07-01

    So far 15 radio galaxies have been detected in the gamma-ray domain by CGRO/EGRET and Fermi/LAT, with a few detections also in the VHE range. We search for distinguishing parameters and estimate the total number of gamma-ray emitting radio galaxies that are potentially detectable by Fermi/LAT. We use Fermi/LAT data in comparison with X-ray and hard X-ray data in order to constrain basic parameters such as the total power of the inverse Compton branch and the position of its peak. We search for possible correlations between the radio, UV, X-ray, and gamma-ray domain and derive the number counts distribution. We then compare their properties with those of the radio galaxies in the 3CRR and SMS4 catalogues. The data show no correlation between the peak of the inverse Compton emission and its luminosity. For the gamma-ray detected radio galaxies the luminosities in the various bands are correlated, except for the UV band, but there is no indication of a correlation of peak frequency or luminosity with the spectral slopes in the X-ray or gamma-ray band. The comparison with other bright radio galaxies shows that the gamma-ray detected objects are among those that have the largest X-ray but rather moderate radio fluxes. Their UV and X-ray luminosities are similar, but gamma-ray detected radio galaxies are predominantly of type FR-I, while the 3CRR sample contains mainly FR-II objects. The number counts of the so far gamma-ray detected radio galaxies shows a very shallow slope, indicating that potentially a fraction of radio galaxies has been missed so far or has not been identified as such, although the predicted number of 22 ± 7 is consistent with the observed 15 objects.

  3. Investigation of WW$\\gamma$ couplings

    CERN Document Server

    Kim, C S; Song, H S; Kim, C S; Lee, Jungil; Song, H S

    1995-01-01

    We investigated how measurements of weak boson production at high energy ep and e\\gamma collisions can provide important information on anomalous WW\\gamma couplings. We also considerd the sinlge muon production through the virtual W-decay at the Pohang Light Source (PLS) facility, and found this process is not adequate to be detected at the PLS until a large luminosity (\\sim 10^{33}/sec/cm^2) Free Electron Laser is installed.

  4. Two-gluon exchange contribution to elastic $\\gamma \\gamma \\to \\gamma \\gamma$ scattering and production of two-photons in ultraperipheral ultrarelativistic heavy ion and proton-proton collisions

    CERN Document Server

    Klusek-Gawenda, Mariola; Szczurek, Antoni

    2016-01-01

    We discuss the two-gluon exchange contribution (formally three-loops) to elastic photon-photon scattering in the high-energy approximation. The elastic $\\gamma\\gamma \\to \\gamma \\gamma$ amplitude is given in the impact-factor representation for all helicity configurations and finite quark masses. We discuss the importance of including the charm quark, which contribution, due to interference, can enhance the cross section considerably. We investigate the contribution to the $\\gamma \\gamma \\to \\gamma \\gamma$ amplitude from the soft region, by studying its dependence on nonperturbative gluon mass. Helicity-flip contributions are shown to be much smaller than helicity-conserving ones. We identify region(s) of phase space where the two-gluon exchange contribution becomes important ingredient compared to box and nonperturbative VDM-Regge mechanisms considered in the literature. Consequences for the $A A \\to A A \\gamma \\gamma$ reaction are discussed. Several differential distributions are shown. A feasibility study t...

  5. Gamma, x-ray reduction system. Volume I: gamma

    International Nuclear Information System (INIS)

    The starting premises for this data reduction system were (a) the individual researcher needs all the accuracy that can be achieved but he has neither the time nor the inclination to learn how to achieve it, and (b) if the data reduction system is to be centralized the people operating it will want to minimize conversation with the computer. This is a working system. All spectral data are stored on Data General 4234 discs after background normalization and strip. Storage is initiated from magnetic tapes loaded by detached pulse height analyzers or directly from Scorpio pulse height analyzers. The only restrictions placed on the individual researchers are that the pulse height analyzer energy scale be set up consistently, that a recovery standard be run at least once every day of use, and the total acquisition system be calibrated to its range of use. In many instances, and if desirable, the latter is provided as a service. At the time of writing this gamma data reduction system is actively being used to calculate net peak areas, activities with or without time correction, activations analysis results, counting precisions, and dynamic limits of detection for the spectral data output of 17 detached pulse height analyzers. To all modes of data reduction are applied background subtraction, random summing correction, detector recovery factor correction, peak interfernce correction (second-order product interference for activation analysis), geometry function correction, acquisition time decay corrections, external and internal sorber correction. All of this is accomplished and a customer report typed in a readable format after a halfline of noninteractive instruction

  6. Cosmic gamma-ray studies at Srinagar

    International Nuclear Information System (INIS)

    Cosmic gamma ray studies being carried out at the Nuclear Research Laboratory at Srinagar and Gulmarg are described and some of the results of observation and possible conclusions are mentioned. These studies use ground base techniques which can detect short-time scale gamma ray bursts from supernovae and primordial black hole (PBH) and also high energy gamma rays from various point sources. A large area photomultiplier system is employed to detect pulses of visible fluorescence radiation which is caused by a gamma ray burst of supernovae of PBH origin. However, any signal out a large number of signals recorded at Gulmarg could not be identified as coinciding with any such event observed elsewhere. It shows that the size of the burst source cannot exceed 30 km., which is in agreement with neutron-star source models. An array using plastic scintillator detectors at the corner of a 10 metre square has been set up at Gulmarg to detect air-shower due to high energy gamma rays. Cerenkov light pulses recorded at Gulmarg have been projected on the sidereal map. A significant excess observed in the right ascension range 20 +- 3 h suggests the possible presence of a quasic-periodic source of gamma rays of energy greater than 1014 eV in the general direction of Cygnus X-3. Future programme of studies is mentioned. (K.M.)

  7. Gamma-ray pulsar studies with COMPTEL

    Science.gov (United States)

    Hermsen, W.; Kuiper, L.; Diehl, R.; Lichti, G.; Schoenfelder, V.; Strong, A. W.; Connors, A.; Ryan, J.; Bennett, K.; Busetta, M.; Carraminana, A.; Buccheri, R.; Grenier, I. A.

    1994-06-01

    Since the launch of the Compton Gamma-Ray Observatory (CGRO) the number of detected gamma-ray pulsars increased from two to six. COMPTEL, on-board CGRO and sensitive to gamma-rays with energies between approximately 0.7 and 30 MeV, detected three of these unambiguously. The classical Crab and Vela pulsars have been observed on several occasions and detailed pulse patterns and spectral parameters have been derived. The new CGRO gamma-ray pulsar PSR B1509-58 has been detected by COMPTEL at a significance level above 4 sigma, consistently in a timing and spatial analysis. A likely detection of Geminga has been obtained at an approximately 3 sigma level. This indication is found in a phase interval in which COS B data showed the presence of a new variable component, Interpeak 2, exhibiting a very soft spectrum above 50 MeV. The diversities in light-curve sphapes and spectral distributions, the apparent time variabilities, and the significant differences in the fractions of the spin-down power radiated at gamma-ray energies in this small sample of gamma-ray pulsars pose important constraints to pulsar modeling.

  8. Gamma Putty dosimetric studies in electron beam

    Directory of Open Access Journals (Sweden)

    Aime M Gloi

    2016-01-01

    Full Text Available Traditionally, lead has been used for field shaping in megavoltage electron beams in radiation therapy. In this study, we analyze the dosimetric parameters of a nontoxic, high atomic number (Z = 83, bismuth-loaded material called Gamma Putty that is malleable and can be easily molded to any desired shape. First, we placed an ionization chamber at different depths in a solid water phantom under a Gamma Putty shield of thickness (t = 0, 3, 5, 10, 15, 20, and 25 mm, respectively and measured the ionizing radiation on the central axis (CAX for electron beam ranging in energies from 6 to 20 MeV. Next, we investigated the relationship between the relative ionization (RI measured at a fixed depth for several Gamma Putty shield at different cutout diameters ranging from 2 to 5 cm for various beam energies and derived an exponential fitting equation for clinical purposes. The dose profiles along the CAX show that bremsstrahlung dominates for Gamma Putty thickness >15 mm. For high-energy beams (12-20 MeV and all Gamma Putty thicknesses up to 25 mm, RI below 5% could not be achieved due to the strong bremsstrahlung component. However, Gamma Putty is a very suitable material for reducing the transmission factor below 5% and protecting underlying normal tissues for low-energy electron beams (6-9 MeV.

  9. Gamma irradiation of peanut (Arachis hypogaea L.)

    International Nuclear Information System (INIS)

    This study was conducted to determine some effects of gamma radiation on peanut (Arachis hypogaea L.). The biological parameters used to evaluate these effects were: % emergence of irradiated seeds, % survival of plants, growth rate, chlorophyll mutations, morphological changes and yield potential. Seeds were irradiated with dose levels of 2.5, 5, 10, 15, 20, 25, 30 and 40 KK per hour of gamma radiation from a Co-60 source. In general, % of emergence and survival in the M1 gene ration decreased with increasing doses of gamma radiation. Morphological changes induced by gamma radiation in the M1 generation of peanut were: leaf flecks, thickened leaves, red purple seeds and red colored seed coat. Generally, frequency of these morphological changes increased with increasing doses of gamma radiation. Protein and fat contents were increased by 2.8% to 1.5% respectively, while starch content decreased with 2.6% in the M2. On the basis of the results obtained, gamma radiation is an effective mutagenic agent in inducing various morphological and genetic changes in peanut

  10. Gamma-Ray Bursts: The End Game

    Science.gov (United States)

    Lamb, Don

    1997-11-01

    The nature of gamma-ray bursts has been one of the greatest unsolved mysteries in astrophysics for more than a quarter century. A major reason for this is that no definite counterparts to the bursts could be found at other wavelengths, despite intense efforts spanning more than two decades. Consequently, the study of gamma-ray bursts has been isolated from the rest of astronomy. Scientists studying them have had only the laws of physics and the bursts themselves to guide them in attempting to solve the burst mystery. All of this changed dramatically with the discovery earlier this year of fading X-ray and optical sources in the arcminute-sized positional error boxes of several gamma-ray bursts. For the first time, temporal, as well as spatial, coincidence could be used to associate these X-ray and optical sources with the gamma-ray bursts. As a result, the odds are great that the fading X-ray and optical sources are counterparts of the bursts, and that the study of gamma-ray bursts has finally been connected with the rest of astronomy. In this talk, we describe the dramatic new information about the nature of gamma-ray bursts that the X-ray, optical, and radio observations of the fading sources have provided, and emphasize the implications that this information has for the distance scale to the bursts.

  11. Egret observations of the extragalactic gamma-ray emission

    DEFF Research Database (Denmark)

    Sreekumar, P.; Bertsch, D.L.; Dingus, B.L.;

    1998-01-01

    The all-sky survey in high-energy gamma rays (E > 30 MeV) carried out by EGRET aboard the Compton Gamma Ray Observatory provides a unique opportunity to examine in detail the diffuse gamma-ray emission. The observed diffuse emission has a Galactic component arising from cosmic-ray interactions...... likely explanation for the origin of this extragalactic high-energy gamma-ray emission is that it arises primarily from unresolved gamma-ray-emitting blazars....

  12. Recombinant mouse interferon-gamma regulation of antibody production.

    OpenAIRE

    Johnson, H M; Torres, B A

    1983-01-01

    Interferon-gamma produced in monkey cells by transfection with mouse interferon-gamma cDNA suppressed the mouse in vitro antibody response in a manner similar to that of natural mouse interferon-gamma. Significant suppression was obtained with as little as 1 U of interferon. Recombinant human interferon-gamma produced by cloning in a similar fashion was not suppressive. Both the suppressive and the antiviral activities of recombinant interferon-gamma were neutralized by antibodies to mouse na...

  13. Search for Charmonium States Decaying to J/psi gamma gamma Using Initial-State Radiation Events

    CERN Document Server

    Aubert, B; Bóna, M; Boutigny, D; Couderc, F; Karyotakis, Yu; Lees, J P; Poireau, V; Tisserand, V; Zghiche, A; Graugès-Pous, E; Palano, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Battaglia, M; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Gill, M S; Groysman, Y; Jacobsen, R G; Kadyk, J A; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Mir, L M; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Wenzel, W A; Del Amo-Sánchez, P; Barrett, M; Ford, K E; Hart, A J; Harrison, T J; Hawkes, C M; Morgan, S E; Watson, A T; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schröder, T; Steinke, M; Boyd, J T; Burke, J P; Cottingham, W N; Walker, D; Asgeirsson, D J; Çuhadar-Dönszelmann, T; Fulsom, B G; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Khan, A; Kyberd, P; Saleem, M; Sherwood, D J; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, Y K; Best, D S; Bondioli, M; Bruinsma, M; Chao, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M A; Mommsen, R K; Röthel, W; Stoker, D P; Abachi, S; Buchanan, C; Foulkes, S D; Gary, J W; Long, O; Shen, B C; Wang, K; Zhang, L; Hadavand, H K; Hill, E J; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Cunha, A; Dahmes, B; Hong, T M; Kovalskyi, D; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Nesom, G; Schalk, T; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dvoretskii, A; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Blanc, F; Bloom, P C; Chen, S; Ford, W T; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Olivas, A; Ruddick, W O; Smith, J G; Ulmer, K A; Wagner, S R; Zhang, J; Chen, A; Eckhart, E A; Soffer, A; Toki, W H; Wilson, R J; Winklmeier, F; Zeng, Q; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Merkel, J; Petzold, A; Spaan, B; Brandt, T; Klose, V; Lacker, H M; Mader, W F; Nogowski, R; Schubert, J; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, C; Verderi, M; Clark, P J; Gradl, W; Muheim, F; Playfer, S; Robertson, A I; Xie, Y; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Prencipe, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Lo Vetere, M; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Brandenburg, G; Chaisanguanthum, K S; Morii, M; Wu, J; Dubitzky, R S; Marks, J; Schenk, S; Uwer, U; Bard, D J; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Flack, R L; Nash, J A; Nikolich, M B; Panduro-Vazquez, W; Behera, P K; Chai, X; Charles, M J; Mallik, U; Meyer, N T; Ziegler, V; Cochran, J; Crawley, H B; Dong, L; Eyges, V; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gritsan, A V; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Davier, M; Grosdidier, G; Höcker, A; Le Diberder, F R; Lepeltier, V; Lutz, A M; Oyanguren, A; Pruvot, S; Rodier, S; Roudeau, P; Schune, M H; Stocchi, A; Wang, W F; Wormser, G; Cheng, C H; Lange, D J; Wright, D M; Chavez, C A; Forster, I J; Fry, J R; Gabathuler, E; Gamet, R; George, K A; Hutchcroft, D E; Payne, D J; Schofield, K C; Touramanis, C; Bevan, A J; Di Lodovico, F; Menges, W; Sacco, R; Cowan, G; Flächer, H U; Hopkins, D A; Jackson, P S; McMahon, T R; Ricciardi, S; Salvatore, F; Wren, A C; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; Naisbit, M T; Williams, J C; Yi, J I; Chen, C; Hulsbergen, W D; Jawahery, A; Lae, C K; Roberts, D A; Simi, G; Blaylock, G; Dallapiccola, C; Hertzbach, S S; Li, X; Moore, T B; Saremi, S; Stängle, H; Cowan, R; Sciolla, G; Sekula, S J; Spitznagel, M; Taylor, F; Yamamoto, R K; Kim, H; Mclachlin, S E; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Simard, M; Taras, P; Viaud, F B; Nicholson, H; Cavallo, N; De Nardo, Gallieno; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; Snoek, H L; Jessop, C P; LoSecco, J M; Allmendinger, T; Benelli, G; Corwin, L A; Gan, K K; Honscheid, K; Hufnagel, D; Jackson, P D; Kagan, H; Kass, R; Rahimi, A M; Regensburger, J J; Ter-Antonian, R; Wong, Q K; Blount, N L; Brau, J E; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Gaz, A; Margoni, M; Morandin, M; Pompili, A; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; Del Buono, L; La Vaissière, C de; Hamon, O; Hartfiel, B L; John, M J J; Leruste, P; Malcles, J; Ocariz, J; Roos, L; Therin, G; Gladney, L; Panetta, J; Biasini, M; Covarelli, R; Angelini, C; Batignani, G; Bettarini, S; Bucci, F; Calderini, G; Carpinelli, M; Cenci, R; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Mazur, M A; Morganti, M; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Haire, M; Judd, D; Wagoner, D E; Biesiada, J; Danielson, N; Elmer, P; Lau, Y P; Lü, C; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; D'Orazio, A; Del Re, D; Di Marco, E; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Safai-Tehrani, F; Voena, C; Ebert, M; Schröder, H; Waldi, R; Adye, T; De Groot, N; Franek, B; Olaiya, E O; Wilson, F F; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Hamel de Monchenault, G; Kozanecki, Witold; Legendre, M; Vasseur, G; Yéche, C; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Berger, N; Claus, R; Coleman, J P; Convery, M R; Cristinziani, M; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W M; Field, R C; Glanzman, T; Gowdy, S J; Graham, M T; Grenier, P; Halyo, V; Hast, C; Hrynóva, T; Innes, W R; Kelsey, M H; Kim, P; Leith, D W G S; Li, S; Luitz, S; Lüth, V; Lynch, H L; MacFarlane, D B; Marsiske, H; Messner, R; Müller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Pulliam, T; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Stelzer, J; Su, D; Sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Vavra, J; Van Bakel, N; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Yi, K; Young, C C; Burchat, P R; Edwards, A J; Majewski, S A; Petersen, B A; Roat, C; Wilden, L; Ahmed, S; Alam, M S; Bula, R; Ernst, J A; Jain, V; Pan, B; Saeed, M A; Wappler, F R; Zain, S B; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Ritchie, J L; Satpathy, A; Schilling, C J; Schwitters, R F; Izen, J M; Lou, X C; Ye, S; Bianchi, F; Gallo, F; Gamba, D; Bomben, M; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Dittongo, S; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martínez-Vidal, F; Banerjee, Sw; Bhuyan, B; Brown, C M; Fortin, D; Hamano, K; Kowalewski, R V; Nugent, I M; Roney, J M; Sobie, R J; Back, J J; Harrison, P F; Latham, T E; Mohanty, G B; Pappagallo, M; Band, H R; Chen, X; Cheng, B; Dasu, S; Datta, M; Flood, K T; Hollar, J J; Kutter, P E; Mellado, B; Mihályi, A; Pan, Y; Pierini, M; Prepost, R; Wu, S L; Yu, Z; Neal, H; al, et

    2006-01-01

    We study the processes e+e- -> (J/psi gamma gamma) gamma and e+e- -> (J/psi pi- pi+) gamma where the hard photon radiated from an initial e+e- collision with center-of-mass (CM) energy near 10.58 GeV is detected. In the final state J/psi gamma gamma we consider J/psi pi0, J/psi eta, chi_{c1} gamma, and chi_{c2} gamma candidates. The invariant mass of the hadronic final state defines the effective e+e- CM energy in each event, so these data can be compared with direct e+e- measurements. We report 90% CL upper limits for the integrated cross section times branching fractions of the J/psi gamma gamma channels in the Y(4260) mass region.

  14. A Search for Gamma-Ray Bursts and Pulsars, and the Application of Kalman Filters to Gamma-Ray Reconstruction

    OpenAIRE

    Jones, B B

    2002-01-01

    Part I describes the analysis of periodic and transient signals in EGRET data. A method to search for the transient flux from gamma-ray bursts independent of triggers from other gamma-ray instruments is developed. Several known gamma-ray bursts were independently detected, and there is evidence for a previously unknown gamma-ray burst candidate. Statistical methods using maximum likelihood and Bayesian inference are developed and implemented to extract periodic signals from gamma-ray sources ...

  15. Measurement of $\\Gamma(\\eta \\to \\pi^+\\pi^-\\gamma)/\\Gamma(\\eta \\to \\pi^+\\pi^-\\pi^0)$ with KLOE experiment

    CERN Document Server

    Ambrosino, F; Antonelli, M; Archilli, F; Balwierz, I; Bencivenni, G; Bini, C; Bloise, C; Bocchetta, S; Bossi, F; Branchini, P; Capon, G; Capussela, T; Ceradini, F; Ciambrone, P; Czerwiski, E; De Lucia, E; De Santis, A; De Simone, P; De Zorzi, G; Denig, A; Di Domenico, A; Di Donato, C; Di Micco, B; Dreucci, M; Felici, G; Fiore, S; Franzini, P; Gatti, C; Gauzzi, P; Giovannella, S; Graziani, E; Jacewicz, M; Lee-Franzini, J; Martemianov, M; Martini, M; Massarotti, P; Meola, S; Miscetti, S; Morello, G; Moulson, M; Muller, S; Napolitano, M; Nguyen, F; Palutan, M; Passeri, A; Patera, V; Longhi, I Prado; Santangelo, P; Sciascia, B; Silarski, M; Spadaro, T; Taccini, C; Tortora, L; Venanzoni, G; Versaci, R; Xu, G; Zdebik, J; Badoni, D; Bocci, V; Budano, A; Bulychjev, S A; Campana, P; Dané, E; De Robertis, G; Domenici, D; Erriquez, O; Fanizzi, G; Gonnella, F; Happacher, F; Höistad, B; Iarocci, E; Johansson, T; Kulikov, V; Kupsc, A; Loddo, F; Matsyuk, M; Messi, R; Moricciani, D; Moskal, P; Ranieri, A; Sarra, I; Schioppa, M; Sciubba, A; Wiślicki, W; Wolke, M

    2011-01-01

    We report the measurement of the ratio $\\Gamma(\\eta \\to \\pi^+\\pi^-\\gamma)/\\Gamma(\\eta \\to \\pi^+\\pi^-\\pi^0)$ analyzing a large sample of $\\phi \\to \\eta \\gamma$ decays recorded with the KLOE experiment at the DA$\\Phi$NE $e^+ e^-$ collider, corresponding to an integrated luminosity of 558 pb$^{-1}$. The $\\eta \\to \\pi^+\\pi^-\\gamma$ process is supposed to proceed both via a resonant contribution, mediated by the $\\rho$ meson, and a non resonant direct term, connected to the box anomaly. The presence of the direct term affects the partial width value. Our result $R_{\\eta}=\\Gamma(\\eta \\to \\pi^+ \\pi^- \\gamma)/\\Gamma(\\eta \\to \\pi^+ \\pi^- \\pi^0)= 0.1838\\pm 0.0005_{stat} \\pm 0.0030_{syst}$ is in agreement with a recent CLEO measurement, which differs by more 3 $\\sigma$ from the average of previous results.

  16. Measurement of the Branching Ratio Gamma(D_s^* -> D_s pi0)/Gamma(D_s^* --> D_s gamma)

    CERN Document Server

    Aubert, B; Boutigny, D; Couderc, F; Gaillard, J M; Hicheur, A; Karyotakis, Yu; Lees, J P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, Michael T; Shelkov, V G; Wenzel, W A; Barrett, M; Ford, K E; Harrison, T J; Hart, A J; Hawkes, C M; Morgan, S E; Watson, A T; Fritsch, M; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Wilson, F F; Çuhadar-Dönszelmann, T; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Thiessen, D; Khan, A; Kyberd, P; Teodorescu, L; Blinov, A E; Blinov, V E; Druzhinin, V P; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M A; Mommsen, R K; Röthel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Foulkes, S D; Gary, J W; Shen, B C; Wang, K; Del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Eisner, A M; Heusch, C A; Lockman, W S; Nesom, G; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S M; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Smith, J G; Zhang, J; Zhang, L; Chen, A; Harton, J L; Soffer, A; Toki, W H; Wilson, R J; Zeng, Q L; Altenburg, D; Brandt, T; Brose, J; Dickopp, M; Feltresi, E; Hauke, A; Lacker, H M; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Petzold, A; Schubert, J; Schubert, Klaus R; Schwierz, R; Spaan, B; Sundermann, J E; Bernard, D; Bonneaud, G R; Brochard, F; Grenier, P; Schrenk, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Bard, D J; Clark, P J; Lavin, D; Muheim, F; Playfer, S; Xie, Y; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Brandenburg, G; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Nikolich, M B; Taylor, G P; Charles, M J; Grenier, G J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F R; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Chavez, C A; Coleman, J P; Forster, I J; Fry, J R; Gabathuler, Erwin; Gamet, R; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Mohanty, G B; Cowan, G; Flack, R L; Flächer, H U; Green, M G; Jackson, P S; McMahon, T R; Ricciardi, S; Salvatore, F; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hodgkinson, M C; Lafferty, G D; Lyon, A J; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Stängle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L M; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Taras, P; Nicholson, H; Fabozzi, F; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M; Bulten, H; Raven, G; Snoek, H L; Wilden, L; Jessop, C P; LoSecco, J M; Gabriel, T A; Allmendinger, T; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Rahimi, A M; Ter-Antonian, R; Wong, Q K; Brau, J E; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; La Vaissière, C de; Del Buono, L; Hamon, O; John, M J J; Leruste, P; Malcles, J; Ocariz, J; Pivk, M; Roos, L; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martínez-Vidal, F; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lau, Y P; Lü, C; Miftakov, V; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai-Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B J; Geddes, N I; Gopal, G P; Olaiya, E O; Aleksan, Roy; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel de Monchenault, G; Kozanecki, Witold; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yéche, C; Zito, M; Purohit, M V; Weidemann, A W; Wilson, J R; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmüller, O L; Claus, R; Convery, M R; Cristinziani, M; De Nardo, Gallieno; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W M; Elsen, E E; Fan, S; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hast, C; Hrynóva, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Lüth, V; Lynch, H L; Marsiske, H; Messner, R; Müller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Vavra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Young, C C; Burchat, Patricia R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bóna, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R V; Roney, J M; Sobie, R J; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Graham, M; Hollar, J J; Johnson, J R; Kutter, P E; Li, H; Liu, R; Mihályi, A; Mohapatra, A K; Pan, Y; Prepost, R; Rubin, A E; Sekula, S J; Tan, P; Von Wimmersperg-Töller, J H; Wu, J; Wu, S L; Yu, Z; Greene, M G; Neal, H

    2004-01-01

    The (Delta I = 1) decay D_s^* --> Ds pi0 and (\\Delta I = 0) decay D_s^* --> Ds gamma have been reconstructed using 90.4 fb^-1 of data recorded by the BaBar detector at the PEP-II asymmetric-energy e^+e^- collider. The relative branching fraction of isospin violating decay to isospin conserving decay has been measured. Our preliminary result for this ratio is Gamma(D_s^* -> D_s pi0)/Gamma(D_s^* --> D_s gamma) = 0.0621 +/- 0.0049 (stat) +/- 0.0063 (syst). In addition we reconstruct the decays D^* --> D0 pi0 and D^* --> D0 gamma for completeness and measure a preliminary relative branching fraction to be Gamma(D^* --> D0 pi0)/Gamma(D&* --> D0 gamma) = = 1.740 +/- 0.020 (stat) +/- 0.125 (syst). Both measurements represent significant improvements over present world averages.

  17. Measuring anomalous WW$\\gamma$ and t$\\bar{\\text{t}}\\gamma$ couplings using top+$\\gamma$ production at the LHC

    CERN Document Server

    Etesami, Seyed Mohsen; Najafabadi, Mojtaba Mohammadi

    2016-01-01

    We consider the electroweak production of a top quark in association with a photon at the LHC to probe the electroweak top quark couplings (t$\\bar{\\text{t}}\\gamma$) as well as the triple gauge boson couplings (WW$\\gamma$). The study is based on the modifications of the t$\\bar{\\text{t}}\\gamma$ and WW$\\gamma$ interactions via heavy degrees of freedom in the form of dimension-six operators which we add to the standard model Lagrangian. A binned angular asymmetry in single top quark plus photon events and cross section ratio are proposed to probe the anomalous t$\\bar{\\text{t}}\\gamma$ and WW$\\gamma$ couplings. It is shown that the proposed angular asymmetry can distinguish anomalous t$\\bar{\\text{t}}\\gamma$, WW$\\gamma$ couplings from the standard model prediction and yield a great sensitivity.

  18. On the equation $p \\frac{\\Gamma(\\frac{n}{2}-\\frac{s}{p-1})\\Gamma(s+\\frac{s}{p-1})}{\\Gamma(\\frac{s}{p-1})\\Gamma(\\frac{n-2s}{2}-\\frac{s}{p-1})} =\\frac{\\Gamma(\\frac{n+2s}{4})^2}{\\Gamma(\\frac{n-2s}{4})^2}$

    OpenAIRE

    Luo, Senping; Wei, Juncheng; Zou, Wenming

    2016-01-01

    The note is aimed at giving a complete characterization of the following equation: $$\\displaystyle p\\frac{\\Gamma(\\frac{n}{2}-\\frac{s}{p-1})\\Gamma(s+\\frac{s}{p-1})}{\\Gamma(\\frac{s}{p-1})\\Gamma(\\frac{n-2s}{2}-\\frac{s}{p-1})} =\\frac{\\Gamma(\\frac{n+2s}{4})^2}{\\Gamma(\\frac{n-2s}{4})^2}.$$ The method is based on some key transformation and the properties of the Gamma function. Applications to fractional nonlinear Lane-Emden equations will be given.

  19. Higgs, SUSY and the Standard Model at $\\gamma\\gamma$ Colliders

    CERN Document Server

    Hagiwara, K

    2001-01-01

    In this report I surveyed physics potential of the gamma-gamma option of a Linear e+e- Collider with the following questions in mind: What new discovery can be expected at a gamma-gamma collider in addition to what will be learned at its `parent' e+e- Linear Collider? By taking account of the hard energy spectrum and polarization of colliding photons, produced by Compton back-scattering of laser light off incoming e- beams, we find that a gamma-gamma collider is most powerful when new physics appears in the neutral spin-zero channel at an invariant mass below about 80% of the c.m. energy of the colliding e-e- system. If a light Higgs boson exists, its properties can be studied in detail, and if its heavier partners or a heavy Higgs boson exists in the above mass range, they may be discovered at a gamma-gamma collider. CP property of the scalar sector can be explored in detail by making use of linear polarization of the colliding photons, decay angular correlations of final state particles, and the pattern of ...

  20. Consequences of the gamma-gamma attenuation in GRBs: a detailed study

    CERN Document Server

    Hascoët, R; Mochkovitch, R; Vennin, V

    2011-01-01

    Recent detections of GeV photons in a few GRBs by Fermi-LAT have led to strong constraints on the bulk Lorentz factor in GRB outflows. To avoid a large gamma-gamma optical depth, minimum values of the Lorentz factor have been estimated to be as high as 800-1200 in some bursts. Here we present a detailed calculation of the gamma-gamma optical depth taking into account both the geometry and the dynamics of the jet. In the framework of the internal shock model, we compute lightcurves in different energy bands and the corresponding spectrum and we show how the limits on the Lorentz factor can be significantly lowered compared to previous estimates. Our detailed model of the propagation of high energy photons in GRB outflows is also appropriate to study many other consequences of gamma-gamma annihilation in GRBs: (i) the gamma-gamma cutoff transition in a time-integrated spectrum is expected to be closer to a power-law steepening of the spectrum than to a sharp exponential decay; (ii) the temporal evolution of the...

  1. On the difference between gamma-ray-detected and non-gamma-ray-detected pulsars

    CERN Document Server

    Rookyard, Simon C; Johnston, Simon; Kerr, Matthew

    2016-01-01

    We compare radio profile widths of young, energetic gamma-ray-detected and non-gamma-ray-detected pulsars. We find that the latter typically have wider radio profiles, with the boundary between the two samples exhibiting a dependence on the rate of rotational energy loss. We also find that within the sample of gamma-ray-detected pulsars, radio profile width is correlated with both the separation of the main gamma-ray peaks and the presence of narrow gamma-ray components. These findings lead us to propose that these pulsars form a single population where the main factors determining gamma ray detectability are the rate of rotational energy loss and the proximity of the line of sight to the rotation axis. The expected magnetic inclination angle distribution will be different for radio pulsars with and without detectable gamma rays, naturally leading to the observed differences. Our results also suggest that the geometry of existing radio and outer-magnetosphere gamma-ray emission models are at least qualitative...

  2. Single Higgs-boson production through gamma-gamma scattering within the general 2HDM

    CERN Document Server

    Bernal, Nicolas; Sola, Joan

    2009-01-01

    The production of a single neutral Higgs boson h through (loop-induced) gamma-gamma collisions is explored in the context of the linear colliders within the general Two-Higgs-Doublet Model (2HDM). Two different mechanisms are analyzed: on the one hand, the scattering gamma gamma-> h of two real photons in a gamma-gamma collider; on the other, the more traditional mechanism of virtual photon fusion, e+e- -->e+e- + h. Owing to the peculiar properties of the Higgs boson self-interactions within the general 2HDM, we find that the overall production rates can be boosted up significantly, provided the charged Higgs mass is not too heavy. For example, if the latter is slightly above 100 GeV and, in addition, the lightest CP-even Higgs boson falls in the ballpark of the LEP bound on the SM Higgs mass up to a few hundred GeV, the cross-sections may typically render \\sigma(gamma gamma-> h)= 0.1-1 pb and \\sigma(e+e- --> e+e- + h)\\sim 0.01 pb -- in both cases well above the SM prediction. Although for charged Higgs masse...

  3. Development of a Second Generation Bovigam Interferon Gamma (IFN-gamma) Assay

    Science.gov (United States)

    In search for better tools to control bovine tuberculosis, the development of diagnostic tests with improved performance and enhanced ease-of-use has a high priority. BOVIGAM®, a rapid laboratory assay, measures gamma interferon (IFN-gamma) production in whole blood samples after induction of a ce...

  4. Gamma-Ray Lenses for Astrophysics-and the Gamma-Ray Imager Mission GRI

    DEFF Research Database (Denmark)

    Wunderer, C. B.; Ballmoos, P. V.; Barriere, N.;

    2009-01-01

    Observations of the gamma-ray sky reveal the most powerful sources and the most violent events in the Universe. While at lower wavebands the observed emission is generally dominated by thermal processes, the gamma-ray sky provides us with a view on the non-thermal Universe. Here particles are acc...

  5. Gravitational Light Bending Prevents $\\gamma\\gamma$ Absorption in Gravitational Lenses

    CERN Document Server

    Boettcher, Markus

    2016-01-01

    The magnification effect due to gravitational lensing enhances the chances of detecting moderate-redshift ($z \\sim 1$) sources in very-high-energy (VHE; $E > 100$ GeV) $\\gamma$-rays by ground-based Atmospheric Cherenkov Telescope facilities. It has been shown in previous work that this prospect is not hampered by potential $\\gamma-\\gamma$ absorption effects by the intervening (lensing) galaxy, nor by any individual star within the intervening galaxy. In this paper, we expand this study to simulate the light-bending effect of a realistic ensemble of stars. We first demonstrate that, for realistic parameters of the galaxy's star field, it is extremely unlikely (probability $\\lesssim 10^{-6}$) that the direct line of sight between the $\\gamma$-ray source and the observer passes by any star in the field close enough to be subject to significant $\\gamma\\gamma$ absorption. Our simulations then focus on the rare cases where $\\gamma\\gamma$ absorption by (at least) one individual star might be non-negligible. We show ...

  6. Measurement of gamma gamma* --> pi0 transition form factor at Belle

    OpenAIRE

    The Belle Collaboration; Uehara, S.; Watanabe, Y.; Nakazawa, H; Adachi, I.; Aihara, H.; Asner, D. M.; Aushev, T.; Bakich, A. M.; Belous, K.; Bhardwaj, V.; Bhuyan, B.; Bischofberger, M.; Bondar, A.; Bonvicini, G.

    2012-01-01

    We report a measurement of the process gamma gamma* --> pi0 with a 759 fb^{-1} data sample recorded with the Belle detector at the KEKB asymmetric-energy e+e- collider. The pion transition form factor, F(Q^2), is measured for the kinematical region 4 GeV^2

  7. Higgs Boson Self-Coupling at High Energy $\\gamma \\gamma$ Collider

    CERN Document Server

    Gutierrez-Rodriguez, A; Sampayo, O A

    2011-01-01

    We analyzed the double production and the triple self-coupling of the standard model Higgs boson at future $\\gamma \\gamma$ collider energies, with the reactions $\\gamma\\gamma \\rightarrow f \\bar f HH$ $(f=b, t)$. We evaluated the total cross section for $f\\bar fHH$ and calculated the total number of events considering the complete set of Feynman diagrams at tree-level and for different values of the triple coupling $\\kappa\\lambda_{HHH}$. We have also analyzed the sensitivity for the considered reaction and we show the results as 95% C.L. regions in the $\\kappa-M_H$ plane for different values of the center of mass energy and different levels of background. The numerical computation was done for the energies which are expected to be available at a possible Future Linear $\\gamma\\gamma$ Collider with a center-of-mass energy 500-3000 $GeV$ and luminosities of 1 and $5 ab^{-1}$. We found that the number of events for the process $\\gamma\\gamma \\rightarrow t \\bar t HH$, taking into account the decay products of both $...

  8. Searches for ttH and tH with H \\rightarrow \\gamma \\gamma

    CERN Document Server

    Cinca, Diane; The ATLAS collaboration

    2016-01-01

    Presentation of the latest results concerning ttH with Higgs decaying to gamma gamma for 13 TeV data. Results are from both ATLAS and CMS. The talk is planned for Top2016, September 19-23, in Olomouc.

  9. Perspectives of the GAMMA-400 space observatory for high-energy gamma rays and cosmic rays measurements

    Science.gov (United States)

    Topchiev, N. P.; Galper, A. M.; Bonvicini, V.; Adriani, O.; Aptekar, R. L.; Arkhangelskaja, I. V.; Arkhangelskiy, A. I.; Bakaldin, A. V.; Bergstrom, L.; Berti, E.; Bigongiari, G.; Bobkov, S. G.; Boezio, M.; Bogomolov, E. A.; Bonechi, S.; Bongi, M.; Bottai, S.; Castellini, G.; Cattaneo, P. W.; Cumani, P.; Dalkarov, O. D.; Dedenko, G. L.; De Donato, C.; Dogiel, V. A.; Finetti, N.; Gorbunov, M. S.; Gusakov, Yu V.; Hnatyk, B. I.; Kadilin, V. V.; Kaplin, V. A.; Kaplun, A. A.; Kheymits, M. D.; Korepanov, V. E.; Larsson, J.; Leonov, A. A.; Loginov, V. A.; Longo, F.; Maestro, P.; Marrocchesi, P. S.; Men'shenin, A. L.; Mikhailov, V. V.; Mocchiutti, E.; Moiseev, A. A.; Mori, N.; Moskalenko, I. V.; Naumov, P. Yu; Papini, P.; Pearce, M.; Picozza, P.; Rappoldi, A.; Ricciarini, S.; Runtso, M. F.; Ryde, F.; Serdin, O. V.; Sparvoli, R.; Spillantini, P.; Stozhkov, Yu I.; Suchkov, S. I.; Taraskin, A. A.; Tavani, M.; Tiberio, A.; Tyurin, E. M.; Ulanov, M. V.; Vacchi, A.; Vannuccini, E.; Vasilyev, G. I.; Yurkin, Yu T.; Zampa, N.; Zirakashvili, V. N.; Zverev, V. G.

    2016-02-01

    The GAMMA-400 gamma-ray telescope is intended to measure the fluxes of gamma-rays and cosmic-ray electrons and positrons in the energy range from 100 MeV to several TeV. Such measurements concern the following scientific tasks: investigation of point sources of gamma-rays, studies of the energy spectra of Galactic and extragalactic diffuse emission, studies of gamma-ray bursts and gamma-ray emission from the Sun, as well as high precision measurements of spectra of high-energy electrons and positrons. Also the GAMMA- 400 instrument provides the possibility for protons and nuclei measurements up to knee. But the main goal for the GAMMA-400 mission is to perform a sensitive search for signatures of dark matter particles in high-energy gamma-ray emission. To fulfill these measurements the GAMMA-400 gamma-ray telescope possesses unique physical characteristics in comparison with previous and present experiments. The major advantage of the GAMMA-400 instrument is excellent angular and energy resolution for gamma-rays above 10 GeV. The GAMMA-400 experiment will be installed onboard of the Navigator space platform, manufactured by the NPO Lavochkin Association. The expected orbit will be a highly elliptical orbit (with apogee 300.000 km and perigee 500 km) with 7 days orbital period. An important profit of such an orbit is the fact that the full sky coverage will always be available for gamma ray astronomy.

  10. New insights from cosmic gamma rays

    Science.gov (United States)

    Roland, Diehl

    2016-04-01

    The measurement of gamma rays from cosmic sources at ~MeV energies is one of the key tools for nuclear astrophysics, in its study of nuclear reactions and their impacts on objects and phenomena throughout the universe. Gamma rays trace nuclear processes most directly, as they originate from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. Additionally, the unique gamma-ray signature from the annihilation of positrons falls into this astronomical window and is discussed here: Cosmic positrons are often produced from β-decays, thus also of nuclear physics origins. The nuclear reactions leading to radioactive isotopes occur inside stars and stellar explosions, which therefore constitute the main objects of such studies. In recent years, both thermonuclear and core-collapse supernova radioactivities have been measured though 56Ni, 56Co, and 44Ti lines, and a beginning has thus been made to complement conventional supernova observations with such measurements of the prime energy sources of supernova light created in their deep interiors. The diffuse radioactive afterglow of massive-star nucleosynthesis in gamma rays is now being exploited towards astrophysical studies on how massive stars feed back their energy and ejecta into interstellar gas, as part of the cosmic cycle of matter through generations of stars enriching the interstellar gas and stars with metals. Large interstellar cavities and superbubbles have been recognised to be the dominating structures where new massive-star ejecta are injected, from 26Al gamma-ray spectroscopy. Also, constraints on the complex interiors of stars derive from the ratio of 60Fe/26Al gamma rays. Finally, the puzzling bulge-dominated intensity distribution of positron annihilation gamma rays is measured in greater detail, but still not understood; a recent microquasar flare provided evidence that such objects may be prime sources for positrons in interstellar space, rather than

  11. Environmental monitoring and in situ gamma spectrometry

    International Nuclear Information System (INIS)

    The in-situ gamma ray spectrometry is widely used for monitoring of the natural as well as man-made radionuclides and corresponding gamma fields in the environment or working places. It finds effective application in the operational and accidental monitoring of the nuclear facilities and their vicinity, radioactive contamination measurements, environmental, radiation hygiene and radiation safety studies, etc. Knowledge of the used detection system response function/matrix makes it possible to analyze measured gamma fields characteristics, calculate energy distributions of the dosimetric quantities in these fields and/or calculate the concentrations of radionuclides in the environment (usually in the soil surface layer). Method of the gamma spectrometry data processing, based on the detector response knowledge, can be applied as for scintillation or semiconductor detection systems and ground measurements, as for airborne spectrometry monitoring. Methods for calculation of angular-energy distributions of gamma fields, originated from typical sources (using Monte Carlo simulation) are discussed as well as methods for calculation of detection systems responses and/or response matrixes in such gamma fields. Techniques of the measured spectra deconvolution and calculation of the dosimetric quantities energy distributions are overviewed. Method and results of calculations of the conversion factors for radionuclides concentrations determination from the measured and calculated photon fluencies energy distributions are discussed (including possibility to set a user-defined radionuclide depth distribution for given experimental data processing). Method (based on detection system response matrix Monte Carlo calculation) developed for the processing and analyzing data from airborne spectrometry monitoring and mapping is described. Sensitivity, achievable precision and some factors influencing the interpretation of results and their accuracy using considered methods are

  12. The Infrared-Gamma-Ray Connection: A WISE View of the Extragalactic Gamma-Ray Sky

    CERN Document Server

    Massaro, F

    2016-01-01

    Using data from the WISE all-sky survey we discovered that the non-thermal infrared (IR) emission of blazars, the largest known population of extragalactic gamma-ray sources, has peculiar spectral properties. In this work, we confirm and strengthen our previous analyses using the latest available releases of both the WISE and the Fermi source catalogs. We also show that there is a tight correlation between the mid-IR colors and the gamma-ray spectral index of Fermi blazars. We name this correlation "the infrared--gamma-ray connection". We discuss how this connection links both the emitted powers and the spectral shapes of particles accelerated in jets arising from blazars over ten decades in energy. Based on this evidence, we argue that the infrared--gamma-ray connection is stronger than the well known radio--gamma-ray connection.

  13. Search for X(3872) in gamma gamma Fusion and ISR at CLEO

    CERN Document Server

    Dobbs, S; Metreveli, Z V; Seth, K K; Tomaradze, A G; Zweber, P; Ernst, J; Mahmood, A H; Severini, H; Asner, D M; Dytman, S A; Love, W; Mehrabyan, S S; Müller, J A; Savinov, V; Li, Z; López, A; Méndez, H; Ramírez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shibata, E I; Shipsey, I P J; Adams, G S; Chasse, M; Cravey, M; Cummings, J P; Danko, I; Napolitano, J; Cronin-Hennessy, D; Park, C S; Park, W; Thayer, J B; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Artuso, M; Boulahouache, C; Blusk, S; Butt, J; Dambasuren, E; Dorjkhaidav, O; Menaa, N; Mountain, R; Muramatsu, H; Nandakumar, R; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Bornheim, A; Pappas, S P; Weinstein, A J; Rosner, J L; Briere, R A; Chen, G P; Ferguson, T; Tatishvili, G T; Vogel, H; Watkins, M E; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Credé, V; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gittelman, B; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hsu, L; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shepherd, M R; Stroiney, S; Sun, W M; Thayer, J G; Urner, D; Wilksen, T; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stöck, H; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Gollin, G D; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; Thaler, J J; Williams, J; Wiss, J; Edwards, K W; Besson, D; Pedlar, T K; Gao, K Y; Gong, D T; Kubota, Y; Lang, B W; Li, S Z; Poling, R A; Scott, A W; Smith, A; Stepaniak, C J

    2004-01-01

    We report on a search for the recently reported X(3872) state using 15.1 fb^{-1} e+ e- data taken in the \\sqrt{s} = 9.46-11.30 GeV region. Separate searches for the production of X(3872) in untagged gamma-gamma fusion and e+ e- annihilation following initial state radiation (ISR) are made by taking advantage of the unique correlation of J/psi -> l+ l- in X(3872) decay to pi+ pi- J/psi. No signals are observed in either case, and 90% confidence upper limits are established as (2J+1)\\Gamma_{\\gamma\\gamma}B(X -> pi+ pi- J/psi) pi+ pi- J/psi) < 8.3 eV.

  14. Measurement of K{sup {+-}}{yields}{pi}{sup {+-}}{gamma}{gamma} decays

    Energy Technology Data Exchange (ETDEWEB)

    Morales Morales, Cristina

    2009-07-21

    The goal of this thesis was an experimental test of an effective theory of strong interactions at low energy, called Chiral Perturbation Theory (ChPT). Weak decays of kaon mesons provide such a test. In particular, K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} decays are interesting because there is no tree-level O(p{sup 2}) contribution in ChPT, and the leading contributions start at O(p{sup 4}). At this order, these decays include one undetermined coupling constant, c. Both the branching ratio and the spectrum shape of K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} decays are sensitive to this parameter. O(p{sup 6}) contributions to K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} ChPT predict a 30-40% increase in the branching ratio. From the measurement of the branching ratio and spectrum shape of K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} decays, it is possible to determine a model dependent value of c and also to examine whether the O(p{sup 6}) corrections are necessary and enough to explain the rate. About 40% of the data collected in the year 2003 by the NA48/2 experiment have been analyzed and 908 K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} candidates with about 8% background contamination have been selected in the region with z=m{sup 2}{sub {gamma}}{sub {gamma}}/m{sub K}{sup 2}{>=}0.2. Using 5,750,121 selected K{sup {+-}} {yields} {pi}{sup {+-}}{pi}{sup 0} decays as normalization channel, a model independent differential branching ratio of K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma} has been measured to be: BR(K{sup {+-}} {yields} {pi}{sup {+-}}{gamma}{gamma}, z{>=}0.2)=(1.018{+-}0.038{sub stat}{+-}0.039{sub syst}{+-}0.004{sub ext}).10{sup -6}. From the fit to the O(p{sup 6}) ChPT prediction of the measured branching ratio and the shape of the z-spectrum, a value of c=1.54{+-}0.15{sub stat}{+-}0.18{sub syst} has been extracted. Using the measured c value and the O(p{sup 6}) ChPT prediction, the branching ratio for z=m{sup 2}{sub

  15. GammaSem Proceedings. A Nordic seminar for users of gamma spectrometry

    International Nuclear Information System (INIS)

    The project GammaSem was proposed to the NKS in 2008. The aim of the project was to arrange two seminars for users of gamma spectrometry, in 2009 and 2010. The seminars were meant to provide a forum for discussions and sharing of information on practical issues concerning gamma spectrometry and initiate a network of gamma spectrometry users in the Nordic countries. Such a Nordic network should strengthen the collaboration between laboratories and improve all participants' competence in practical gamma spectrometry. Both seminars' focus was practical challenges met by the users themselves, rather than theoretical matters. Scientists and users of gamma spectrometry from all five Nordic countries were invited to the seminar, as well as scientist from the Baltic countries. A total of 65 people signed up for GammaSem 2010; representing 30 different universities, commercial companies, research institutes and authorities. The working group concept as presented at last year's GammaSem, has not worked out as intended. The reason for this is probably because most of the laboratories that signed up to join the working groups, signed up because they wanted to learn more about the different subjects. In combination with the fact that no funding was made available for the working groups, it was difficult to establish goals on what to achieve. None of the working groups applied for funding from the NKS (or elsewhere) to establish separate projects. There is a big need for more cooperation and for training within the field of gamma spectrometry. This fact has been proved through these two seminars, both by the many different topics that have been discussed, but also by the huge interest for participating in the suggested series of workshop. The GammaSem seminars have thus provided a much welcomed starting point for a broader Nordic collaboration. (Author)

  16. GammaSem Proceedings. A Nordic seminar for users of gamma spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Straalberg, E. (ed.) (Institute for Energy Technolgy (Norway)); Berg, K. (National Institute of Radiation Protection (Denmark)); Dowdall, M. (Norwegian Radiation Protection Authority (Norway)) (and others)

    2010-11-15

    The project GammaSem was proposed to the NKS in 2008. The aim of the project was to arrange two seminars for users of gamma spectrometry, in 2009 and 2010. The seminars were meant to provide a forum for discussions and sharing of information on practical issues concerning gamma spectrometry and initiate a network of gamma spectrometry users in the Nordic countries. Such a Nordic network should strengthen the collaboration between laboratories and improve all participants' competence in practical gamma spectrometry. Both seminars' focus was practical challenges met by the users themselves, rather than theoretical matters. Scientists and users of gamma spectrometry from all five Nordic countries were invited to the seminar, as well as scientist from the Baltic countries. A total of 65 people signed up for GammaSem 2010; representing 30 different universities, commercial companies, research institutes and authorities. The working group concept as presented at last year's GammaSem, has not worked out as intended. The reason for this is probably because most of the laboratories that signed up to join the working groups, signed up because they wanted to learn more about the different subjects. In combination with the fact that no funding was made available for the working groups, it was difficult to establish goals on what to achieve. None of the working groups applied for funding from the NKS (or elsewhere) to establish separate projects. There is a big need for more cooperation and for training within the field of gamma spectrometry. This fact has been proved through these two seminars, both by the many different topics that have been discussed, but also by the huge interest for participating in the suggested series of workshop. The GammaSem seminars have thus provided a much welcomed starting point for a broader Nordic collaboration. (Author)

  17. The antiviral response to gamma interferon.

    Science.gov (United States)

    Costa-Pereira, Ana P; Williams, Timothy M; Strobl, Birgit; Watling, Diane; Briscoe, James; Kerr, Ian M

    2002-09-01

    A role for alpha/beta interferon (IFN-alpha/beta) in the IFN-gamma antiviral response has long been suggested. Accordingly, possible roles for autocrine or double-stranded-RNA (dsRNA)-induced IFN-alpha/beta in the IFN-gamma response were investigated. Use was made of wild-type and a variety of mutant human fibrosarcoma cell lines, including mutant U5A cells, which lack a functional IFN-alpha/beta receptor and hence an IFN-alpha/beta response. IFN-gamma did not induce detectable levels of IFN-alpha/beta in any of the cell lines, nor was the IFN-gamma response per se dependent on autocrine IFN-alpha/beta. On the other hand, a number of responses to dsRNA [poly(I). poly(C)] and encephalomyocarditis virus were greatly enhanced by IFN-gamma pretreatment (priming) of wild-type cells or of mutant cells lacking an IFN-alpha/beta response; these include the primary induction of dsRNA-inducible mRNAs, including IFN-beta mRNA, and, to a lesser extent, the dsRNA-mediated activation of the p38 mitogen-activated protein (MAP) kinase(s). IFN-gamma priming of mRNA induction by dsRNA is dependent on JAK1 and shows biphasic kinetics, with an initial rapid (<30-min) response being followed by a more substantial effect on overnight incubation. The IFN-gamma-primed dsRNA responses appear to be subject to modulation through the p38, phosphatidylinositol 3-kinase, and ERK1/ERK2 MAP kinase pathways. It can be concluded that despite efficient priming of IFN-beta production, the IFN-alpha/beta pathways play no significant role in the primary IFN-gamma antiviral response in these cell-virus systems. The observed IFN-gamma priming of dsRNA responses, on the other hand, will likely play a significant role in combating virus infection in vivo.

  18. Influence of the temperature in the measurement of the gamma automatic probe Gamma Tracer; Influencia de la temperatura en la medicion de la sonda gamma automatica Gamma Tracer

    Energy Technology Data Exchange (ETDEWEB)

    Caveda R, C.A.; Dominguez L, O.; Alonso A, D. [CPHR, Calle 20 No. 4113 e/41 y 47, Playa, C.P. 11300, A.P. 6195, C.P. 10600 La Habana (Cuba); Montalvan E, A.; Fabelo B, O. [CIAC, Ave. Finlay Km 2 1/2, Rpto. Puerto Principe, Camaguey 70800 (Cuba)]. e-mail: caveda@cphr.edu.cu

    2006-07-01

    In the following work an analysis of the existent relationship among the measurement of the absorbed dose rate in air due to the environmental gamma radiation and the temperature, magnitudes measured to intervals of 10 minutes by the gamma probe Gamma Tracer located in the post of occident of the National Net of Environmental Radiological Surveillance (RNVRA), in the Center of Protection and Hygiene of the Radiations (CPHR) is made. For it its were analyzed near 100,000 measurements corresponding to the period 2004-2005. For a better processing and interpretation of the data, these were analyzed with one frequency time zone and monthly using the Gamma Red software to which was necessary to add it some options. Finally it was submitted the probe to a heating process inside a stove. The results of the carried out experiments confirmed that the absorbed dose rate in air due to the environmental gamma radiation depends potentially of the probe temperature in the range of environmental temperature to which is subjected daily the same one. (Author)

  19. GRI: the gamma-ray imager mission

    CERN Document Server

    Knödlseder, J

    2006-01-01

    Observations of the gamma-ray sky reveal the most powerful sources and the most violent events in the Universe. While at lower wavebands the observed emission is generally dominated by thermal processes, the gamma-ray sky provides us with a view on the non-thermal Universe. Here particles are accelerated to extreme relativistic energies by mechanisms which are still poorly understood, and nuclear reactions are synthesizing the basic constituents of our world. Cosmic accelerators and cosmic explosions are the major science themes that are addressed in the gamma-ray regime. With the INTEGRAL observatory, ESA has provided a unique tool to the astronomical community revealing hundreds of sources, new classes of objects, extraordinary views of antimatter annihilation in our Galaxy, and fingerprints of recent nucleosynthesis processes. While INTEGRAL provides the global overview over the soft gamma-ray sky, there is a growing need to perform deeper, more focused investigations of gamma-ray sources. In soft X-rays a...

  20. Gamma Radiation Effects on Peanut Skin Antioxidants

    Directory of Open Access Journals (Sweden)

    Adriano Costa de Camargo

    2012-03-01

    Full Text Available Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached-deodorized (RBD soybean oil. The oxidative stability of the oil samples was determined using the Oil Stability Index method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ. Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. All extracts, gamma irradiated or not, presented increasing induction period (h, measured by the Oil Stability Index method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT. The present study confirmed that gamma radiation did not affect the peanut skin extracts’ antioxidative properties when added to soybean oil.

  1. Gamma radiation effects on peanut skin antioxidants.

    Science.gov (United States)

    de Camargo, Adriano Costa; de Souza Vieira, Thais Maria Ferreira; Regitano-D'Arce, Marisa Aparecida Bismara; Calori-Domingues, Maria Antonia; Canniatti-Brazaca, Solange Guidolin

    2012-01-01

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached-deodorized (RBD) soybean oil. The oxidative stability of the oil samples was determined using the Oil Stability Index method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ). Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. All extracts, gamma irradiated or not, presented increasing induction period (h), measured by the Oil Stability Index method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT. The present study confirmed that gamma radiation did not affect the peanut skin extracts' antioxidative properties when added to soybean oil.

  2. Status of the Milagro Gamma Ray Observatory

    CERN Document Server

    Maryland Univ. College Park

    2001-01-01

    The Milagro Gamma Ray Observatory, located at an altitude of 8,600 feet in the Jemez Mountains of New Mexico, is the world's first large-area water Cherenkov detector capable of continuously monitoring the entire sky for sources of TeV gamma rays. It is uniquely capable of searching for transient sources of VHE gamma rays. The core of the detector is a 60m x 80m x 8m pond instrumented with 723 PMTs deployed in two layers. This part of the detector is complete and has operated continuously since Jan. 2000. Initial studies including searches for gamma-ray sources are ongoing, and preliminary results are available. The final stage of construction is under way. We are deploying 170 auxiliary "outrigger" water Cherenkov detectors in an area of 40,000 square-meters surrounding the pond, which will significantly enhance our ability to reject background and more accurately reconstruct the gamma-ray direction and energy. In addition, we are lowering the energy threshold of the detector by using custom processing to en...

  3. Stellar Photon Archaeology with Gamma-Rays

    Science.gov (United States)

    Stecker, Floyd W.

    2009-01-01

    Ongoing deep surveys of galaxy luminosity distribution functions, spectral energy distributions and backwards evolution models of star formation rates can be used to calculate the past history of intergalactic photon densities and, from them, the present and past optical depth of the Universe to gamma-rays from pair production interactions with these photons. The energy-redshift dependence of the optical depth of the Universe to gamma-rays has become known as the Fazio-Stecker relation (Fazio & Stecker 1970). Stecker, Malkan & Scully have calculated the densities of intergalactic background light (IBL) photons of energies from 0.03 eV to the Lyman limit at 13.6 eV and for 0$ < z < $6, using deep survey galaxy observations from Spitzer, Hubble and GALEX and have consequently predicted spectral absorption features for extragalactic gamma-ray sources. This procedure can also be reversed. Determining the cutoff energies of gamma-ray sources with known redshifts using the recently launched Fermi gamma-ray space telescope may enable a more precise determination of the IBL photon densities in the past, i.e., the "archaeo-IBL.", and therefore allow a better measure of the past history of the total star formation rate, including that from galaxies too faint to be observed.

  4. Gamma-Ray Astronomy from the Ground

    CERN Document Server

    Horns, D

    2016-01-01

    The observation of cosmic gamma-rays from the ground is based upon the detection of gamma-ray initiated air showers. At energies between approximately $10^{11}$ eV and $10^{13}$ eV, the imaging air Cherenkov technique is a particularly successful approach to observe gamma-ray sources with energy fluxes as low as $\\approx 10^{-13}$ erg\\,cm$^{-2}\\,$s$^{-1}$. The observations of gamma-rays in this energy band probe particle acceleration in astrophysical plasma conditions and are sensitive to high energy phenomena beyond the standard model of particle physics (e.g., self-annihilating or decaying dark matter, violation of Lorentz invariance, mixing of photons with light pseudo-scalars). The current standing of the field and its major instruments are summarised briefly by presenting selected highlights. A new generation of ground based gamma-ray instruments is currently under development. The perspectives and opportunities of these future facilities will be discussed.

  5. GAMPIX: A new generation of gamma camera

    Science.gov (United States)

    Gmar, M.; Agelou, M.; Carrel, F.; Schoepff, V.

    2011-10-01

    Gamma imaging is a technique of great interest in several fields such as homeland security or decommissioning/dismantling of nuclear facilities in order to localize hot spots of radioactivity. In the nineties, previous works led by CEA LIST resulted in the development of a first generation of gamma camera called CARTOGAM, now commercialized by AREVA CANBERRA. Even if its performances can be adapted to many applications, its weight of 15 kg can be an issue. For several years, CEA LIST has been developing a new generation of gamma camera, called GAMPIX. This system is mainly based on the Medipix2 chip, hybridized to a 1 mm thick CdTe substrate. A coded mask replaces the pinhole collimator in order to increase the sensitivity of the gamma camera. Hence, we obtained a very compact device (global weight less than 1 kg without any shielding), which is easy to handle and to use. In this article, we present the main characteristics of GAMPIX and we expose the first experimental results illustrating the performances of this new generation of gamma camera.

  6. Dielectric relaxation of gamma irradiated muscovite mica

    Energy Technology Data Exchange (ETDEWEB)

    Kaur, Navjeet [Department of Physics, Guru Nanak Dev University, Amritsar, Punjab 143005 (India); Singh, Mohan, E-mail: mohansinghphysics@gmail.com [Department of Physics, Guru Nanak Dev University, Amritsar, Punjab 143005 (India); Singh, Lakhwant [Department of Physics, Guru Nanak Dev University, Amritsar, Punjab 143005 (India); Awasthi, A.M. [Thermodynamics Laboratory, UGC-DAE Consortium for Scientific Research, Indore 452001 (India); Lochab, S.P. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India)

    2015-03-15

    Highlights: • The present article reports the effect of gamma irradiation on the dielectric relaxation characteristics of muscovite mica. • Dielectric and electrical relaxations have been analyzed in the framework of dielectric permittivity, electric modulus and Cole–Cole formalisms. • The frequency dependent electrical conductivity has been rationalized using Johnsher’s universal power law. • The experimentally measured electric modulus and conductivity data have been fitted using Havriliak–Negami dielectric relaxation function. - Abstract: In the present research, the dielectric relaxation of gamma irradiated muscovite mica was studied in the frequency range of 0.1 Hz–10 MHz and temperature range of 653–853 K, using the dielectric permittivity, electric modulus and conductivity formalisms. The dielectric constants (ϵ′ and ϵ′′) are found to be high for gamma irradiated muscovite mica as compared to the pristine sample. The frequency dependence of the imaginary part of complex electric modulus (M′′) and dc conductivity data conforms Arrhenius law with single value of activation energy for pristine sample and two values of activation energy for gamma irradiated mica sample. The experimentally assessed electric modulus and conductivity information have been interpreted by the Havriliak–Negami dielectric relaxation explanation. Using the Cole–Cole framework, an analysis of real and imaginary characters of the electric modulus for pristine and gamma irradiated sample was executed which reflects the non-Debye relaxation mechanism.

  7. Gamma Reaction History for the NIF

    Energy Technology Data Exchange (ETDEWEB)

    Herrmann, H W; Evans, S C; Kim, Y; Mack, J M; Young, C S; Cox, B C; Frogget, B C; Kaufman, M I; Malone, R M; Tunnell, T W; Stoeffl, W

    2009-06-05

    Bang time and reaction history measurements are fundamental components of diagnosing ICF implosions and will be essential contributors to diagnosing attempts at ignition on the National Ignition Facility (NIF). Fusion gammas provide a direct measure of fusion interaction rate without being compromised by Doppler spreading. Gamma-based gas Cherenkov detectors that convert fusion gamma rays to optical Cherenkov photons for collection by fast recording systems have been developed and fielded at Omega. These systems have established their usefulness in illuminating ICF physics in several experimental campaigns. Bang time precision better than 25 ps has been demonstrated, well below the 50 ps accuracy requirement defined by the NIF System Design Requirements. A staged approach of implementing Gamma Reaction History (GRH) diagnostics on the NIF has been initiated. In the early stage, multiple detectors located close to target chamber center (at 2 and 6 m) and coupled to photomultiplier tubes are geared toward the loweryield THD campaign. In the later stage, streak camera–coupled instruments will be used for improved temporal resolution at the higher yields expected from the DT ignition campaign. Multiple detectors will allow for increased dynamic range and gamma energy spectral information.

  8. Gamma radiographic exposure time indicator

    International Nuclear Information System (INIS)

    In industrial radiography, with the proper selection of source and film, the radiographic quality depends very much on the exposure time, which in turn depends upon the source strength and the source to film distance. Conventional methods to arrive at correct exposure time involve time consuming calculations and in these methods the knowledge of the above mentioned parameters is imperative. An instrument to determine the required exposure time has been developed which indicates exposure times in about 30 secs. This covers two commonly used gamma radiography sources, viz., 192Ir and 60Co and six commonly used radiography films of different speeds. Knowledge of source strength and source to film distance is not required with the use of this instrument. With a knowledge of the total exposure required by the film to give the required sensitivity and by the measurement of radiation level at the film location, the correct exposure time is determined. The radiation level is measured by placing a GM counter behind the radiographic specimen at the film location. To match the responses of the film and the GM counter, the counter is incorporated in a suitably designed probe. In this instruments, an integrator to integrate the GM-pulses and a constant current integrator (timer) are started simultaneously. The voltage at the GM-pulse integrator is compared with a preselected voltage, (selected on the basis of film type, source, source strength and order of object thickness) by a comparator. The comparator is so adjusted that when the GM-pulse integrator voltage exceeds the preselected voltage, it switches its state and stops the integration of constant current. The constant current integrator output which is proportional to the time taken for the GM-pulse integrator to reach the preselected voltage, is read on a meter graduated in terms of exposure time. The instrument can measure exposure times from 5 minutes to 10 hours read in two ranges, the range-changing being automatic

  9. Urban gamma spectrometry. Report 1

    International Nuclear Information System (INIS)

    This report contains the present status and results for the NKS UGS-project per 1 June 2006 for NKS partners DTU, Denmark, and STUK, Finland. The Danish and Finnish CGS (Carborne Gamma Spectrometry) systems are not of similar types. The Danish CGS system(s) only make use of one NaI(Tl) detector whereas the Finnish CGS system consists of several detectors, NaI(Tl) and HPGe both and as an additional feature the Finnish detectors have position dependent different fields of view. Furthermore, the Finnish system is equipped with an air sampling system. In terms of operation, the Danish detector is located on the rooftop where as the Finnish detectors are located inside the vehicle. The Finnish and the Danish team use different methods for data processing. STUK uses a hypothesis test method to get robust real time alarms (within 10 seconds) when significant peaks from a previously defined set of nuclides are detected. An alarm for a significantly elevated total pulse rate is sent if none of the predefined nuclides is identified. All data are stored to the LINSSI database, which facilitates easy data retrieval for post processing. DEMA/DTU bases their calculations on full spectrum fitting using NASVD and the Danish software NucSpec. Source signals are found from spectrum fitting residuals or from stripping of energy windows - either by the standard 4-windows method or by a measurement based method where stripping factors for any window of interest can be derived from the measurements themselves. A thorough description of the two systems and data processing methods (including mathematics) are described in this report. For the Danish methods of data processing some comparisons have been made, but no final conclusion has been reached yet. Raw urban data has been investigated along with urban data sets to which source signals have been added and searched for. For the Finnish method calibration plots of the minimum detection limits for two different detector types have been

  10. Urban gamma spectrometry. Report 1

    Energy Technology Data Exchange (ETDEWEB)

    Aage, H.K. (Technical Univ. of Denmark, Kgs. Lyngby (Denmark)); Kuukankorpi, S.; Moring, M.; Smolander, P.; Toivonen, H. (Radiation and Nuclear Safety Authority, Helsinki (Finland))

    2009-06-15

    This report contains the present status and results for the NKS UGS-project per 1 June 2006 for NKS partners DTU, Denmark, and STUK, Finland. The Danish and Finnish CGS (Carborne Gamma Spectrometry) systems are not of similar types. The Danish CGS system(s) only make use of one NaI(Tl) detector whereas the Finnish CGS system consists of several detectors, NaI(Tl) and HPGe both and as an additional feature the Finnish detectors have position dependent different fields of view. Furthermore, the Finnish system is equipped with an air sampling system. In terms of operation, the Danish detector is located on the rooftop where as the Finnish detectors are located inside the vehicle. The Finnish and the Danish team use different methods for data processing. STUK uses a hypothesis test method to get robust real time alarms (within 10 seconds) when significant peaks from a previously defined set of nuclides are detected. An alarm for a significantly elevated total pulse rate is sent if none of the predefined nuclides is identified. All data are stored to the LINSSI database, which facilitates easy data retrieval for post processing. DEMA/DTU bases their calculations on full spectrum fitting using NASVD and the Danish software NucSpec. Source signals are found from spectrum fitting residuals or from stripping of energy windows - either by the standard 4-windows method or by a measurement based method where stripping factors for any window of interest can be derived from the measurements themselves. A thorough description of the two systems and data processing methods (including mathematics) are described in this report. For the Danish methods of data processing some comparisons have been made, but no final conclusion has been reached yet. Raw urban data has been investigated along with urban data sets to which source signals have been added and searched for. For the Finnish method calibration plots of the minimum detection limits for two different detector types have been

  11. Treatment with anti-interferon-gamma monoclonal antibodies modifies experimental autoimmune encephalomyelitis in interferon-gamma receptor knockout mice

    DEFF Research Database (Denmark)

    Espejo, C; Penkowa, M; Sáez-Torres, I;

    2001-01-01

    The role of interferon-gamma (IFN-gamma) in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis (EAE) is still controversial. We have studied the function of IFN-gamma and its receptor in the EAE model using two different IFN-gamma receptor knockout (IFN-gamma R......(-/-)) mouse types: C57Bl/6x129Sv, with a disruption of the IFN-gamma receptor cytoplasmic domain, and 129Sv, homozygous for a disrupted IFN-gamma receptor gene. Mice were immunized with peptide 40-55 from rat myelin oligodendrocyte glycoprotein. A subgroup of mice was treated with anti-IFN-gamma monoclonal...... antibodies (mAb) on day 8 postimmunization. Clinical scoring and both histological and immunohistochemical studies were undertaken for all groups. We hereby show that treatment with anti-IFN-gamma mAb worsened the disease course of 129Sv wild-type mice. However, it decreased the mean daily score in IFN...

  12. INTEGRAL & RXTE View of Gamma-ray Binaries

    OpenAIRE

    Jian LI; Torres, Diego F.; Zhang, Shu; WANG, JIANMIN

    2013-01-01

    Gamma-ray binaries are X-ray binaries with gamma-ray emissions. Their multi-wavelength emissions range from radio, optical, X-ray and to very high energy (TeV). X-ray emissions are crucial to understand the nature of gamma-ray binaries. INTEGRAL and RXTE have covered and monitored most of the gamma-ray binaries in hard and soft X-rays. Here we report the results of several gamma-ray binaries and possible gamma-ray binaries from INTEGRAL and RXTE.

  13. Induction of bacterial blight resistance in elite Indian rice (Oryza sativa L.) cultivars using gamma irradiation and ethyl methane sulfonate

    International Nuclear Information System (INIS)

    inoculation following standard techniques. Plants with a lesion length of less than 2.5 cm were scored as resistant. In M2 out of a population of 89045 plants, a total of 40 lines comprising 145 plants (2.46%) were resistant to bacterial blight. A maximum of 16 BB resistant mutant lines were observed in Pusa Basmati 1, whereas there were 24 in PR 106. On a line basis, 24 out of 1876 lines of PR106 segregated for BB resistance leading to a frequency of 1.279%, whereas 16 out of 1953 segregated for BB resistance leading to a frequency of 0.819% in the case of Pusa Basmati 1. When observed in terms of mutagens, 17 out of 24 mutants were induced by EMS in the case of PR 106 whereas for Pusa Basmati 1, 12 out of 16 cases the resistance was induced by gamma irradiation. In a study by Padmanabhan et al (1976) [4], 0.36% resistant and 0.65% moderately resistant plants were obtained in the M2 population derived from EMS treated variety. The rate of successful induction of resistance during the present investigation is comparatively low since the moderately resistant and moderately susceptible plants in the M2 were considered susceptible. The newness of resistance developed in the present study needs to be tested by going for allelic testing and testing against different pathotypes. Induced mutants have been used to develop new BB resistant gene(s) vix. Xa-nm(t) by Nakai et al (1990) and xa-19 by Taura et al (1991). The productive BB resistant lines developed here were grown in plant progeny methods by screening in every generation. Those advanced lines are under field trials and would be used to study the genetics of BB resistance in the future and the release of commercial cultivars for the farming community of this region

  14. Very high count rate gamma spectroscopy

    International Nuclear Information System (INIS)

    Recent improvements in the electronics that amplify and analyze gamma photon-induced pulses have made it possible for HPGe coaxial detectors to accept input rates of one-million, one-MeV gamma photons-per-second and still provide the spectroscopist with spectra that can be analyzed. Data are presented that illustrate peak area variances and changes in counting uncertainty statistics due to the greatly extended count rate range. Software algorithms are presented that allow gain shift and peak resolution to be adjusted automatically on a sample-by-sample basis. Relationships are developed between integrated count rate and the variances of full energy photon peak area and counting uncertainty when using the real time correction mode of pulse processing. Finally, the results of integrating hardware and software into a system are used to illustrate that quantitative gamma spectroscopy over counting rates of one- to one-million counts-per-second are achievable

  15. Nondestructive gamma activation analysis of mineral materials

    International Nuclear Information System (INIS)

    The basic problems are described related to the use of gamma activation analysis. The applicability was studied of instrumental gamma activation analysis (IGAA) in geology. A number of minerals, rocks, marine sediments and reference materials were studied. For irradiation a betatron and a microtron were used. The results show that IGAA allows the simultaneous determination of a number of trace elements at concentrations of tenths of ppm. The results are given of comparisons made of the analytical possibilities of microtron IGAA and reactor INAA in geology. Tables show the results of the application of IGAA, the main products and parameters of photoexcitation reactions and graphically represented are the gamma spectra of measured materials. (J.B.)

  16. Dose rate levels around industrial gamma sources

    International Nuclear Information System (INIS)

    Dose rate levels around two gamma ray sources utilized in a mining corporation have been determined. Both gamma ray sources are 137Cs and are installed in a mining corporation to measure on-line the density of mine products. Dose rate levels were calculated in several sites around the 137Cs sources using two active and several passive thermoluminescent dosemeters. Using the 137Cs' gamma factor dose rates were calculated in all the points. A comparison between the measured and calculated dose rate levels was carried out. Calculated dose rate levels was obtained for three cases: first, assuming the sources were bare, second, assuming the sources inside their shielding and the third, adding an extra shield to reduce the dose rate levels to those similar to local background. (author)

  17. Progress in gamma-camera quality control

    International Nuclear Information System (INIS)

    The latest developments in the art of quality control of gamma cameras are emphasized in a simple historical manner. The exhibit describes methods developed by the Bureau of Radiological Health (BRH) in comparison with previously accepted techniques for routine evaluation of gamma-camera performance. Gamma cameras require periodic testing of their performance parameters to ensure that their optimum imaging capability is maintained. Quality control parameters reviewed are field uniformity, spatial distortion, intrinsic and spatial resolution, and temporal resolution. The methods developed for the measurement of these parameters are simple, not requiring additional electronic equipment or computers. The data has been arranged in six panels as follows: schematic diagrams of the most important test patterns used in nuclear medicine; field uniformity; regional displacements in transmission pattern image; spatial resolution using the BRH line-source phantom; instrinsic resolution using the BRH Test Pattern; and Temporal resolution and count losses at high counting rates

  18. Solution To The Gamma Ray Burst Mystery?

    CERN Document Server

    Dar, Arnon

    1996-01-01

    Photoexcitation and ionization of partially ionized heavy atoms in highly relativistic flows by interstellar photons, followed by their reemission in radiative recombination and decay, boost star-light into beamed $\\gamma$ rays along the flow direction. Repeated excitation/decay of highly relativistic baryonic ejecta from merger or accretion induced collapse of neutron stars in dense stellar regions (DSRs), like galactic cores, globular clusters and super star-clusters, can convert enough kinetic energy in such events in distant galaxies into cosmological gamma ray bursts (GRBs). The model predicts remarkably well all the main observed temporal and spectral properties of GRBs. Its success strongly suggests that GRBs are $\\gamma$ ray tomography pictures of DSRs in galaxies at cosmological distances with unprecedented resolution: A time resolution of $dt\\sim 1~ms$ in a GRB can resolve stars at a Hubble distance which are separated by only $D\\sim 10^{10}cm$. This is equivalent to the resolving power of an optica...

  19. Plasma driven neutron/gamma generator

    Energy Technology Data Exchange (ETDEWEB)

    Leung, Ka-Ngo; Antolak, Arlyn

    2015-03-03

    An apparatus for the generation of neutron/gamma rays is described including a chamber which defines an ion source, said apparatus including an RF antenna positioned outside of or within the chamber. Positioned within the chamber is a target material. One or more sets of confining magnets are also provided to create a cross B magnetic field directly above the target. To generate neutrons/gamma rays, the appropriate source gas is first introduced into the chamber, the RF antenna energized and a plasma formed. A series of high voltage pulses are then applied to the target. A plasma sheath, which serves as an accelerating gap, is formed upon application of the high voltage pulse to the target. Depending upon the selected combination of source gas and target material, either neutrons or gamma rays are generated, which may be used for cargo inspection, and the like.

  20. New insights from cosmic gamma rays

    CERN Document Server

    Diehl, Roland

    2016-01-01

    The measurement of gamma rays from cosmic sources at MeV energies is one of the key tools for nuclear astrophysics, in its study of nuclear reactions and their impacts on objects and phenomena throughout the universe. Gamma rays trace nuclear processes most directly, as they originate from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. Additionally, the unique gamma-ray signature from the annihilation of positrons falls into this astronomical window and is discussed here: Cosmic positrons are often produced from beta-decays, thus also of nuclear physics origins. The nuclear reactions leading to radioactive isotopes occur inside stars and stellar explosions, which therefore constitute the main objects of such studies. In recent years, both thermonuclear and core-collapse supernova radioactivities have been measured, and complement conventional supernova observations with measurements of their prime energy sources. The diffuse radioactive afterglow of massi...

  1. Effects of gamma radiation in tomato seeds

    International Nuclear Information System (INIS)

    Tomato dry seeds of the hybrid 'Gladiador' F1 were exposed to low doses of gamma radiation from Co-60 source at 0,509 kGy tax rate in order to study stimulation effects of radiation on germination and plant growth. Eight treatments radiation doses were applied as follows: 0 (control); 2,5; 5,0; 7,5; 10,0; 12,5; 15,0; 20,0 Gy. Seed germination as well as green fruits number, harvested fruit number, fruit weight and total production were assessed to identify occurrence of stimulation. Tomato seeds and plants were handled as for usual tomato production in Brazil. Low doses of gamma radiation treatment in the seeds stimulate germination and substantially increase fruit number and total production up to 86% at 10 Gy dose. There are evidences that the use of low doses of gamma radiation can stimulate germination and plant production thus, showing hormetic effects. (author)

  2. TeV Gamma-Ray Astrophysics

    CERN Document Server

    Ribó, M

    2008-01-01

    The window of TeV Gamma-Ray Astrophysics was opened less than two decades ago, when the Crab Nebula was detected for the first time. After several years of development, the technique used by imaging atmospheric Cherenkov telescopes like HESS, MAGIC or VERITAS, is now allowing to conduct sensitive observations in the TeV regime. Water Cherenkov instruments like Milagro are also providing the first results after years of integration time. Different types of extragalactic and galactic sources have been detected, showing a variety of interesting phenomena that are boosting theory in very high energy gamma-ray astrophysics. Here I review some of the most interesting results obtained up to now, making special emphasis in the field of X-ray/gamma-ray binaries.

  3. Microsecond flares in gamma-ray bursts

    Science.gov (United States)

    Schaefer, Bradley E.; Cohen, Justin; Teegarden, Bonnard J.; Cline, Thomas L.; Fishman, Gerald J.; Meegan, Charles A.; Wilson, Robert B.; Paciesas, William S.; Pendleton, Geoffrey N.; Matteson, James L.

    1993-01-01

    It has been suggested that gamma-ray burst light curves may consist of many superposed flares with a duration shorter than 30/microsec. If true, the implications for the interpretation of burst data are enormous. With the launch of the Compton Gamma-Ray Observatory, four predictions of Mitrofanov's (1989) suggestion can be tested. Our results which contradict this suggestion are (1) the photon arrival times are not correlated between independent detectors, (2) the spectral hardness and intensity does not depend on the detector area, (3) the bursts seen by detectors which measure photon positions do not see microsecond flares, and (4) burst positions deduced from detectors with different projected areas are close to the positions deduced from time-of-flight differences between separated spacecraft. We conclude, therefore, that gamma-ray bursts are not composed of microsecond flares.

  4. Low radioactivity spectral gamma calibration facility

    International Nuclear Information System (INIS)

    A low radioactivity calibration facility has been constructed at the Nevada Test Site (NTS). This facility has four calibration models of natural stone that are 3 ft in diameter and 6 ft long, with a 12 in. cored borehole in the center of each model and a lead-shielded run pipe below each model. These models have been analyzed by laboratory natural gamma ray spectroscopy (NGRS) and neutron activation analysis (NAA) for their K, U, and Th content. Also, 42 other elements were analyzed in the NAA. The 222Rn emanation data were collected. Calibrating the spectral gamma tool in this low radioactivity calibration facility allows the spectral gamma log to accurately aid in the recognition and mapping of subsurface stratigraphic units and alteration features associated with unusual concentrations of these radioactive elements, such as clay-rich zones

  5. Effects of gamma radiation in tomato seeds

    Energy Technology Data Exchange (ETDEWEB)

    Wiendl, Toni A.; Wiendl, Fritz W.; Franco, Suely S.H.; Franco, Jose G.; Althur, Valter, E-mail: tawiendl@hotmail.com, E-mail: gilmita@uol.com.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Arthur, Paula B., E-mail: arthur@cena.usp.br [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil)

    2013-07-01

    Tomato dry seeds of the hybrid 'Gladiador' F1 were exposed to low doses of gamma radiation from Co-60 source at 0,509 kGy tax rate in order to study stimulation effects of radiation on germination and plant growth. Eight treatments radiation doses were applied as follows: 0 (control); 2,5; 5,0; 7,5; 10,0; 12,5; 15,0; 20,0 Gy. Seed germination as well as green fruits number, harvested fruit number, fruit weight and total production were assessed to identify occurrence of stimulation. Tomato seeds and plants were handled as for usual tomato production in Brazil. Low doses of gamma radiation treatment in the seeds stimulate germination and substantially increase fruit number and total production up to 86% at 10 Gy dose. There are evidences that the use of low doses of gamma radiation can stimulate germination and plant production thus, showing hormetic effects. (author)

  6. Probing the H$^{3}$ vertex in e+e-, $\\gamma$e and $\\gamma\\gamma$ collisions for light and intermediate Higgs bosons

    CERN Document Server

    Ilyin, V A; Kurihara, Y; Pukhov, A E; Shimizu, Y

    1996-01-01

    We have studied double Higgs production at future linear colliders while paying special attention to the option of high-energy and high-luminosity photon beams. The main purpose was to examine the feasibility of e+e-, e-gamma and gamma-gamma colliders in order to probe the anomalous triple Higgs coupling, which is crucial for understanding the Standard Model. We considered mainly the cases of light and intermediate Higgs bosons. Double Higgs production is almost background free, except in the MH=MZ mass range, which is discussed separately. It is shown that for a light Higgs boson the HHH coupling can be measured even at e+e- collider at 500 GeV. For a intermediate Higgs boson a collider in the TeV region is suitable for such an investigation. We have estimated the bounds on the anomalous HHH coupling, which can be experimentally established using future linear colliders.

  7. Form factors of the transitions {gamma}{sup *}{pi}{sup 0} {r_arrow} {gamma} and {gamma}{sup *}{eta}{r_arrow}{gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Afanasev, A. [Continuous Electron Beam Accelerator Facility, Newport News, VA (United States)

    1994-04-01

    The author discusses possibilities to study {gamma}*{pi}{sup 0} and {gamma}*{eta} {r_arrow} {gamma} transition form factors at CEBAF energies. The author shows that for 4 GeV electron beam, these form factors can be measured at CEBAF for the 4-momentum transfers Q{sup 2} {le} 2.5 (GeV/c){sup 2} using virtual Compton scattering on the proton and nuclear target in the kinematic regime of low momentum transfers to the target. These measurements can be extended to Q{sup 2} {le} 4.0 (GeV/c){sup 2} using the electron beam with the energy 6 GeV.

  8. A novel fully integrated handheld gamma camera

    Science.gov (United States)

    Massari, R.; Ucci, A.; Campisi, C.; Scopinaro, F.; Soluri, A.

    2016-10-01

    In this paper, we present an innovative, fully integrated handheld gamma camera, namely designed to gather in the same device the gamma ray detector with the display and the embedded computing system. The low power consumption allows the prototype to be battery operated. To be useful in radioguided surgery, an intraoperative gamma camera must be very easy to handle since it must be moved to find a suitable view. Consequently, we have developed the first prototype of a fully integrated, compact and lightweight gamma camera for radiopharmaceuticals fast imaging. The device can operate without cables across the sterile field, so it may be easily used in the operating theater for radioguided surgery. The prototype proposed consists of a Silicon Photomultiplier (SiPM) array coupled with a proprietary scintillation structure based on CsI(Tl) crystals. To read the SiPM output signals, we have developed a very low power readout electronics and a dedicated analog to digital conversion system. One of the most critical aspects we faced designing the prototype was the low power consumption, which is mandatory to develop a battery operated device. We have applied this detection device in the lymphoscintigraphy technique (sentinel lymph node mapping) comparing the results obtained with those of a commercial gamma camera (Philips SKYLight). The results obtained confirm a rapid response of the device and an adequate spatial resolution for the use in the scintigraphic imaging. This work confirms the feasibility of a small gamma camera with an integrated display. This device is designed for radioguided surgery and small organ imaging, but it could be easily combined into surgical navigation systems.

  9. The Prototype of GAMMA-400 Apparatus

    Science.gov (United States)

    Arkhangelskiy, A. I.; Arkhangelskaja, I. V.; Kheymits, M. D.; Runtso, M. F.; Suchkov, S. I.; Topchiev, N. P.; Yurkin, Yu. T.

    Scientific project GAMMA-400 (Gamma-Astronomy Multifunction Modules Apparatus) relates to the new generation of space observatories for investigation of cosmic γ-emission in the energy band from ∼20 MeV up to several TeV, electron/positron fluxes from ∼1 GeV up to ∼10 TeV and cosmic-ray nuclei fluxes with energies up to ∼1015 eV by means of GAMMA-400 gamma-telescope represents the core of the scientific complex. The investigation of gamma ray bursts in the energy band of 10 keV-15 MeV are possible too by means of KONUS-FG apparatus included in the complex. For γ-rays in the energy region from 10 to 100 GeV expected energy resolution changes from ∼3% to ∼1% and angular resolution from ∼0.1% to ∼ 0.01% respectively, γ/protons rejection factor is ∼5·105. The GAMMA-400 satellite will be launched at the beginning of the next decade on the high apogee orbit with following initial parameters: apogee altitude ∼300000 km, perigee altitude ∼500 km, rotation period ∼7 days, inclination to the equator plane 51.4°. The active functioning interval will be 7-10 years. The scientific complex will have next main technical parameters: total weight ∼4100 kg, power consumption ∼2000 W, information quote 100 GByte/day. During the project development, the prototype of apparatus was created for working-off of the main apparatus construction units in laboratory conditions. The main distinctive features of the prototype are presented.

  10. Tolerance of edible flowers to gamma irradiation

    International Nuclear Information System (INIS)

    People have been eating flowers and using them in culinary creations for hundreds of years. Edible flowers are increasingly being used in meals as an ingredient in salads or garnish, entrees, drinks and desserts. The irradiation process is an alternative method that can be used in disinfestation of food and flowers, using doses that do not damage the product. The sensitivity of flowers to irradiation varies from species to species. In the present research was irradiated with doses up to 1 kGy some edible flowers to examine their physical tolerance to gamma-rays. Furthermore, high doses gamma irradiation causes petal withering, browning process and injury in edible flowers. (author)

  11. Beta/gamma test problems for ITS

    International Nuclear Information System (INIS)

    The Integrated Tiger Series of Coupled Electron/Photon Monte Carlo Transport Codes (ITS 3.0, PC Version) was used at Oak Ridge National Laboratory (ORNL) to compare with and extend the experimental findings of the beta/gamma response of selected health physics instruments. In order to assure that ITS gives correct results, several beta/gamma problems have been tested. ITS was used to simulate these problems numerically, and results for each were compared to the problem's experimental or analytical results. ITS successfully predicted the experimental or analytical results of all tested problems within the statistical uncertainty inherent in the Monte Carlo method

  12. Gamma-Ray Bursts: Jets and Energetics

    CERN Document Server

    Frail, D A

    2003-01-01

    The relativistic outflows from gamma-ray bursts are now thought to be narrowly collimated into jets. After correcting for this jet geometry there is a remarkable constancy of both the energy radiated by the burst and the kinetic energy carried by the outflow. Gamma-ray bursts are still the most luminous explosions in the Universe, but they release energies that are comparable to supernovae. The diversity of cosmic explosions appears to be governed by the fraction of energy that is coupled to ultra-relativistic ejecta.

  13. Very high energy gamma ray astrophysics

    International Nuclear Information System (INIS)

    The Whipple Observatory High Resolution Camera will be used in a vigorous program of observations to search for new sources of very-high-energy gamma rays. In addition, a search for antimatter using the moon-earth system as an ion spectrometer will be begun. The first phase of GRANITE, the new 37-element 11-m camera, will be concluded with first light scheduled for September, 1991. The two cameras will operate in support of the Gamma Ray Observatory mission in the winter of 1991/2

  14. Material recognition using fission gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Viesti, G. [Dipartimento di Fisica dell' Universita di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy)], E-mail: giuseppe.viesti@pd.infn.it; Sajo-Bohus, L. [Universidad Simon-Bolivar, Laboratorio Fisica Nuclear, Apartado 8900, 1080 A. Caracas (Venezuela, Bolivarian Republic of); Fabris, D. [INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Lunardon, M.; Moretto, S. [Dipartimento di Fisica dell' Universita di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Nebbia, G.; Pesente, S. [INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy)

    2009-07-21

    Material recognition is studied by measuring the transmission spectrum of {sup 252}Cf fission gamma rays in the energy range E{sub {gamma}}=0.1-5.5 MeV for 0.1-MeV-wide energy bins through a number of elementary samples. Each transmitted spectrum is compared with a library of reference spectra for different elements providing the possibility of material identification. In case of elemental samples with known thickness, this procedure allows the identification of the sample Z with uncertainty typically lower than 3 Z-units over a wide range of elements. Applications to composite materials are also reported.

  15. Storage ability of gamma irradiated mango fruits

    International Nuclear Information System (INIS)

    Extension of shelf-life have been achieved by many methods. the most modern one is using gamma irradiation as a promising technology for the developing nations. The aim of this investigation is to study the effects of gamma irradiation either alone or in combination with Alar or Benlate on 'Hindi Be Senara' mature green fruits and also to determine the optimum treatment and maximum extension in shelf - life. Mature-green 'Hindi be sinara' mango fruits were taken from trees planted in commercial orchard in 'kerdasa'Giza

  16. Effect of Gamma radiation on mycotoxins solutions

    OpenAIRE

    Calado, Thalita; António, Amilcar L.; Rodrigues, Paula; Cabo Verde, Sandra; Abrunhosa, Luís; Venâncio, Armando

    2013-01-01

    Due to the high toxicity of mycotoxins, many methods have been used to reduce or eliminate them from food and feed. Gamma radiation is one technique that has been investigated with some promising results in degradation of some mycotoxins from food. The aim of this study was to clarify the effect of gamma irradiation on aflatoxin B1 (AFB1) aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2), ochatoxin A (OTA) and zearelone (ZEA). The effect of the presence of moisture during the i...

  17. Effect of gamma radiation on mycotoxins solutions

    OpenAIRE

    Calado, Thalita; Antonio, Amilcar L.; Rodrigues, Paula; Cabo Verde, Sandra; Venâncio, Armando

    2013-01-01

    Due to the high toxicity of mycotoxins, many methods have been used to reduce or eliminate them from food and feed. Gamma radiation is one technique that has been investigated with some promising results in degradation of some mycotoxins from food. The aim of this study was to clarify the effect of gamma irradiation on aflatoxin B1 (AFB1) aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2), ochatoxin A (OTA) and zearelone (ZEA). The effect of the presence of moisture during the i...

  18. A Shotgun Model for $\\gamma$ Ray Bursts

    CERN Document Server

    Heinz, S

    1999-01-01

    We propose that gamma ray bursts (GRBs) are produced by a shower of heavy blobs running into circumstellar material at highly relativistic speeds. The gamma ray emission is produced in the shocks these bullets drive into the surrounding medium. The short term variability seen in GRBs is set by the slowing-down time of the bullets while the overall duration of the burst is set by the lifetime of the central engine. A requirement of this model is that the ambient medium be dense, consistent with a strong stellar wind. In contrast to other external shock scenarios, the efficiency of the shock can be close to unity.

  19. Gamma Knife Surgery in Trigeminal Neuralgia.

    Science.gov (United States)

    Wolf, Amparo; Kondziolka, Douglas

    2016-07-01

    Gamma knife surgery (GKS) represents a safe, effective, and relatively durable noninvasive treatment option for patients with trigeminal neuralgia (TN) and recurrent TN. By one year's time, 75% to 90% of patients will have obtained pain relief, defined as Barrow Neurological Institute grades I to IIIB. Similar rates have been demonstrated for patients undergoing a second GKS for recurrent TN. Predictors of durability of GKS in TN include type I TN, post-GKS Barrow Neurological Institute score, and the presence of post-Gamma Knife facial numbness. PMID:27324996

  20. Cytotoxicity of mycotoxins after gamma irradiation

    OpenAIRE

    Calado, Thalita; Verde, S. Cabo; Abrunhosa, Luís; Fernández-Cruz, M.; Venâncio, Armando

    2015-01-01

    Due to the high toxicity of mycotoxins, many methods have been used to reduce or eliminate them from food and feed. Gamma radiation is one technique that has been investigated with some promising results in the degradation of mycotoxins from food commodities. The aims of this study were (i) to clarify the effect of gamma irradiation on aflatoxin B1 (AFB1), aflatoxin B2, aflatoxin G1, aflatoxin G2 and ochratoxin A (OTA); (ii) to evaluate the effect of the presence of water du...

  1. Gamma Radiation Effects on Peanut Skin Antioxidants

    OpenAIRE

    de Camargo, Adriano Costa; Vieira, Thais Maria Ferreira de Souza; Regitano-d’Arce, Marisa Aparecida Bismara; Calori-Domingues, Maria Antonia; Solange Guidolin CANNIATTI-BRAZACA

    2012-01-01

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to...

  2. Gamma ray spectrometer for Lunar Scout 2

    Science.gov (United States)

    Moss, C. E.; Burt, W. W.; Edwards, B. C.; Martin, R. A.; Nakano, George H.; Reedy, R. C.

    1993-01-01

    We review the current status of the Los Alamos program to develop a high-resolution gamma-ray spectrometer for the Lunar Scout-II mission, which is the second of two Space Exploration Initiative robotic precursor missions to study the Moon. This instrument will measure gamma rays in the energy range of approximately 0.1 - 10 MeV to determine the composition of the lunar surface. The instrument is a high-purity germanium crystal surrounded by an CsI anticoincidence shield and cooled by a split Stirling cycle cryocooler. It will provide the abundance of many elements over the entire lunar surface.

  3. Nuclear Forensics using Gamma-ray Spectroscopy

    Science.gov (United States)

    Norman, E. B.

    2016-09-01

    Much of George Dracoulis's research career was devoted to utilising gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the last several years, our research group has made use of both high- and low-resolution gamma-ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  4. Neocortical gamma oscillations in idiopathic generalized epilepsy

    DEFF Research Database (Denmark)

    Benedek, Krisztina; Berenyi, Antal; Gombkoto, Peter;

    2016-01-01

    Objective: Absence seizures in patients with idiopathic generalized epilepsy (IGE) may in part be explained by a decrease in phasic GABAA (type-A c-aminobutyric acid) receptor function, but the mechanisms are only partly understood. Here we studied the relation between ictal and interictal spike...... decrease in the 8-12 Hz frequency band. The rise in EEG gamma oscillations was short-lasting and decreased before activity declined at lower frequency ranges. Compared to control patients, patients with epilepsy also showed higher interictal values of mean coherence of gamma activity, but this interictal...

  5. Tolerance of edible flowers to gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Koike, Amanda C.R.; Araujo, Michel M.; Costa, Helbert S.F.; Almeida, Mariana C.; Villavicencio, Anna Lucia C.H., E-mail: ackoike@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP) Sao Paulo, SP (Brazil)

    2011-07-01

    People have been eating flowers and using them in culinary creations for hundreds of years. Edible flowers are increasingly being used in meals as an ingredient in salads or garnish, entrees, drinks and desserts. The irradiation process is an alternative method that can be used in disinfestation of food and flowers, using doses that do not damage the product. The sensitivity of flowers to irradiation varies from species to species. In the present research was irradiated with doses up to 1 kGy some edible flowers to examine their physical tolerance to gamma-rays. Furthermore, high doses gamma irradiation causes petal withering, browning process and injury in edible flowers. (author)

  6. Observation of J/psi --> 3 gamma

    CERN Document Server

    Adams, G S; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Ma, J S Y; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Méndez, H; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B

    2008-01-01

    We report the first observation of the decay J/psi --> 3 gamma. The signal has a statistical significance of 6 sigma and corresponds to a branching fraction of B(J/psi --> 3 gamma) = (1.2 +- 0.3 +- 0.2) x 10^-5, in which the errors are statistical and systematic, respectively. The measurement uses psi(2S) --> pi+ pi- J/psi events acquired with the CLEO-c detector operating at the CESR e+e- collider.

  7. Zeros in. gamma. +e. -->. W+. nu

    Energy Technology Data Exchange (ETDEWEB)

    Mikaelian, K.O.

    1984-09-01

    We point out a misprint in the differential cross section for ..gamma..e..-->..W..nu.. reported recently by Ginzburg, Kotkin, Parful, and Serbo. The corrected expression has a zero in accordance with the general formula derived earlier by Mikaelian. We plot the angular distribution for different values of kappa, the anomalous-magnetic-moment parameter of the W. We suggest that the reaction ..gamma..e..-->..W..nu.. is an attractive way to measure kappa because the distributions are sensitive to it and the zero exists only if kappa = +1 as in the standard electroweak theory.

  8. Gamma Ray Bursts in the HAWC Era

    CERN Document Server

    Mészáros, Peter; Murase, Kohta; Fox, Derek; Gao, He; Senno, Nicholas

    2015-01-01

    Gamma-Ray Bursts are the most energetic explosions in the Universe, and are among the most promising for detecting multiple non-electromagnetic signals, including cosmic rays, high energy neutrinos and gravitational waves. The multi-GeV to TeV gamma-ray range of GRB could have significant contributions from hadronic interactions, mixed with more conventional leptonic contributions. This energy range is important for probing the source physics, including overall energetics, the shock parameters and the Lorentz factor. We discuss some of the latest observational and theoretical developments in the field.

  9. Gamma radiation background measurements from Spacelab 2

    Science.gov (United States)

    Paciesas, William S.; Gregory, John C.; Fishman, Gerald J.

    1989-01-01

    A Nuclear Radiation Monitor incorporating a NaI(Tl) scintillation detector was flown as part of the verification flight instrumentation on the Spacelab 2 mission, July 29 to August 6, 1985. Gamma-ray spectra were measured with better than 20 s resolution throughout most of the mission in the energy range 0.1 to 30 MeV. Knowledge of the decay characteristics and the geomagnetic dependence of the counting rates enable measurement of the various components of the Spacelab gamma-ray background: prompt secondary radiation, earth albedo, and delayed induced radioactivity. The status of the data analysis and present relevant examples of typical background behavior are covered.

  10. Nuclear forensics using gamma-ray spectroscopy

    CERN Document Server

    Norman, Eric B

    2016-01-01

    Much of George Dracoulis's research career was devoted to utilizing gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the past several years, our research group has made use of both high- and low- resolution gamma ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  11. Nuclear Forensics using Gamma-ray Spectroscopy

    Directory of Open Access Journals (Sweden)

    Norman E. B.

    2016-01-01

    Full Text Available Much of George Dracoulis’s research career was devoted to utilising gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the last several years, our research group has made use of both high- and low-resolution gamma-ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  12. Status of the Milagro $\\gamma$ Ray Observatory

    CERN Document Server

    Atkins, R; Berley, D; Chen, M L; Coyne, D G; Delay, R S; Dingus, B L; Dorfan, D E; Ellsworth, R W; Evans, D; Falcone, A D; Fleysher, L; Fleysher, R; Gisler, G; Goodman, J A; Haines, T J; Hoffman, C M; Hugenberger, S; Kelley, L A; Leonor, I; Macri, J R; McConnell, M; McCullough, J F; McEnery, J E; Miller, R S; Mincer, A I; Morales, M F; Némethy, P; Ryan, J M; Schneider, M; Shen, B; Shoup, A L; Sinnis, G; Smith, A J; Sullivan, G W; Thompson, T N; Tümer, T O; Wang, K; Wascko, M O; Westerhoff, S; Williams, D A; Yang, T; Yodh, G B

    2001-01-01

    The Milagro Gamma Ray Observatory is the world's first large-area water Cherenkov detector capable of continuously monitoring the sky at TeV energies. Located in northern New Mexico, Milagro will perform an all sky survey of the Northern Hemisphere at energies between ~250 GeV and 50 TeV. With a high duty cycle, large detector area (~5000 square meters), and a wide field-of-view (~1 sr), Milagro is uniquely capable of searching for transient and DC sources of high-energy gamma-ray emission. Milagro has been operating since February, 1999. The current status of the Milagro Observatory and initial results will be discussed.

  13. New Precise Measurements of the $\\Xi^{0} \\to \\Lambda \\gamma$ and $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ Decay Asymmetries

    CERN Document Server

    Batley, J R; Lazzeroni, C; Munday, D J; Patel, M; Slater, M W; Wotton, S A; Arcidiacono, R; Bocquet, G; Ceccucci, A; Cundy, D; Doble, N; Falaleev, V; Gatignon, L; Gonidec, A; Grafstrom, P; Kubischta, W; Mikulec, I; Norton, A; Panzer-Steindel, B; Rubin, P; Wahl, H; Goudzovski, E; Hristov, P; Kekelidze, V; Litov, L; Madigozhin, D; Molokanova, N; Potrebenikov, Yu; Stoynev, S; Zinchenko, A; Monnier, E; Swallow, E; Winston, R; Sacco, R; Walker, A; Baldini, W; Gianoli, A; Dalpiaz, P; Frabetti, P L; Martini, M; Petrucci, F; Savrie, M; Scarpa, M; Calvetti, M; Collazuol, G; Iacopini, E; Ruggiero, G; Bizzeti, A; Lenti, M; Veltri, M; Behler, M; Eppard, K; Eppard, M; Hirstius, A; Kleinknecht, K; Koch, U; Marouelli, P; Masetti, L; Moosbrugger, U; Morales-Morales, C; Peters, A; Wanke, R; Winhart, A; Dabrowski, A; Fonseca Martin, T; Velasco, M; Cenci, P; Lubrano, P; Pepe, M; Anzivino, G; Imbergamo, E; Lamanna, G; Michetti, A; Nappi, A; Petrucci, M C; Piccini, M; Valdata, M; Cerri, C; Fantechi, R; Costantini, F; Fiorini, L; Giudici, S; Pierazzini, G; Sozzi, M; Mannelli, I; Cheshkov, C; Cheze, J B; De Beer, M; Debu, P; Gouge, G; Marel, G; Mazzucato, E; Peyaud, B; Vallage, B; Holder, M; Maier, A; Ziolkowski, M; Biino, C; Cartiglia, N; Marchetto, F; Pastrone, N; Clemencic, M; Goy Lopez, S; Menichetti, E; Wislicki, W; Dibon, H; Jeitler, M; Markytan, M; Neuhofer, G; Widhalm, L

    2010-01-01

    The decay asymmetries of the weak radiative Hyperon decays $\\Xi^{0}\\to \\Lambda \\gamma$ and $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ have been measured with high precision using data of the NA48/1 experiment at CERN. From about 52000 $\\Xi^{0}\\to \\Lambda \\gamma$ and 15000 $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ decays, we obtain for the decay asymmetries $\\alpha_{\\Xi^{0}\\to \\Lambda\\gamma}$ = -0.704 +- 0.019$_{stat}$ +- 0.064$_{syst}$ and $\\alpha_{\\Xi^{0}\\to \\Sigma^{0}\\gamma}$ = -0.729 +- 0.030$_{stat}$ +- 0.076$_{syst}$, respectively. These results are in good agreement with previous experiments, but more precise.

  14. Gamma interferon augments Fc gamma receptor-mediated dengue virus infection of human monocytic cells.

    OpenAIRE

    Kontny, U; Kurane, I; Ennis, F A

    1988-01-01

    It has been reported that anti-dengue antibodies at subneutralizing concentrations augment dengue virus infection of monocytic cells. This is due to the increased uptake of dengue virus in the form of virus-antibody complexes by cells via Fc gamma receptors. We analyzed the effects of recombinant human gamma interferon (rIFN-gamma) on dengue virus infection of human monocytic cells. U937 cells, a human monocytic cell line, were infected with dengue virus in the form of virus-antibody complexe...

  15. CP sensitive observables of a hypothetical heavy spin-0 particle with $\\gamma\\gamma-$interactions dominant

    CERN Document Server

    Belyaev, N; Prokofiev, K

    2016-01-01

    We study observables sensitive to tensor structure of interactions of a hypothetical heavy spin-0 particle. It is assumed that the interactions of this particle are primary with photons; interactions with vector bosons $gg$, $WW$, $ZZ$, and quarks $t\\bar{t}$ are suppressed. The above assumptions favor the production of this hypothetical particle through the vector boson fusion mechanism structurally dominated by $\\gamma \\gamma$ and $\\gamma Z$ interactions. This particle will be produced in association with two light quarks. It is shown that the difference in azimuthal angle between the tagging jets provides an observable sensitive to the CP properties of this hypothetical particle.

  16. Resistance of a gamma/gamma prime - delta directionally solidified eutectic alloy to recrystallization

    Science.gov (United States)

    Tewari, S. N.; Scheuermann, C. M.; Andrews, C. W.

    1975-01-01

    The lamellar directionally solidified nickel-base eutectic alloy gamma/gamma prime-delta has potential as an advanced turbine blade material. The microstructural stability of this alloy was investigated. Specimens were plastically deformed by uniform compression or Brinell indentation, then annealed between 705 and 1120 C. Microstructural changes observed after annealing included gamma prime coarsening, pinch-off and spheroidization of delta lamellae, and the appearance of an unidentified blocky phase in surface layers. All but the first of these was localized in severely deformed regions, suggesting that microstructural instability is not a serious problem in the use of this alloy.

  17. High-energy gamma-ray afterglows from low-luminosity gamma-ray bursts

    OpenAIRE

    He, Hao-Ning; WANG, XIANG-YU; Yu, Yun-Wei; Meszaros, Peter

    2009-01-01

    The observations of gamma-ray bursts (GRBs) such as 980425, 031203 and 060218, with luminosities much lower than those of other classic bursts, lead to the definition of a new class of GRBs -- low-luminosity GRBs. The nature of the outflow responsible for them is not clear yet. Two scenarios have been suggested: one is the conventional relativistic outflow with initial Lorentz factor of order of $\\Gamma_0\\ga 10$ and the other is a trans-relativistic outflow with $\\Gamma_0\\simeq 1-2$. Here we ...

  18. Shielding evaluation by laser compton scattering gamma-ray

    International Nuclear Information System (INIS)

    Laser Compton scattering gamma-ray beam was used for evaluation of gamma ray shield. The gamma source of a NewSUBARU Synchrotron Radiation Facility can generate the quasi-monochromatic gamma ray beam of 0.5-1.7 MeV by combining a carbon dioxide laser and a 0.5-1.0 GeV electron beam. This gamma-ray source has small divergence of 1/γ radian due to the relativistic effect, where γ is relativistic factor of electron. Small diameter test beam of gamma-ray of about 1 mm in diameter is possible to use at the 10 m from the gamma-ray source by combining the small divergence gamma-ray beam with small hole lead collimator. Test sample size used was 2 cm in diameter. Measured shield factor was compared with calculated value using known shield materials such as lead. (author)

  19. Gamma rays and supernova explosions. [high temperature radiation measurement

    Science.gov (United States)

    Arnett, W. D.

    1977-01-01

    Thermal radiation associated with the explosion of supernovae is investigated. High temperature is required to produce copious gamma radiation of this sort. It appears that type 11 supernovae do not release much of their energy as gamma ray continuum radiation.

  20. QCD Compositeness as Revealed in Exclusive Vector Boson Reactions through Double-Photon Annihilation: $e^+ e^- \\to \\gamma \\gamma^\\ast \\to \\gamma V^0 $ and $e^+ e^- \\to \\gamma^\\ast \\gamma^\\ast \\to V^0 V^0$

    CERN Document Server

    Brodsky, Stanley J; Lyubovitskij, Valery E

    2016-01-01

    We study the exclusive double-photon annihilation processes, $e^+ e^- \\to \\gamma \\gamma^\\ast\\to \\gamma V^0$ and $e^+ e^- \\to \\gamma^\\ast \\gamma^\\ast \\to V^0_a V^0_b,$ where the $V^0_i$ is a neutral vector meson produced in the forward kinematical region: $s \\gg -t$ and $-t \\gg \\Lambda_{\\rm QCD}^2$. We show how the differential cross sections $\\frac{d\\sigma}{dt}$, as predicted by QCD, have additional falloff in the momentum transfer squared $t$ due to the QCD compositeness of the hadrons, consistent with the leading-twist fixed-$\\theta_{\\rm CM} $ scaling laws. However, even though they are exclusive channels and not associated with the conventional electron-positron annihilation process $e^+ e^- \\to \\gamma^\\ast \\to q \\bar q,$ these total cross sections $\\sigma(e^+ e^- \\to \\gamma V^0) $ and $\\sigma(e^+ e^- \\to V^0_a V^0_b),$ integrated over the dominant forward- and backward-$\\theta_{\\rm CM}$ angular domains, scale as $1/s$, and thus contribute to the leading-twist scaling behavior of the ratio $R_{e^+ e^-}$. W...

  1. LHCb: Measurement of Gamma from $B \\rightarrow DK$ Decays

    CERN Multimedia

    Hussain, N

    2013-01-01

    The angle $\\gamma$ of the CKM Unitarity Triangle is the only one that can be measured directly at tree level. Direct measurements of $\\gamma$ constrain the triangle and any deviations from unity may be an indication of new physics. This poster presents three analyses that look at a variety of $B \\rightarrow DK$ decays, whose information is then combined to perform a $\\gamma$ measurement. The best fit value of $\\gamma$ is ${71.1^{+16.1}_{-15.2}} ^\\circ$.

  2. Interstellar medium structure and content and gamma ray astronomy

    International Nuclear Information System (INIS)

    A general description of gamma-ray astronomy is presented with special emphasis on the study of diffuse gamma-ray emission. This is followed by a collection of reflections and observations on the structure and the gas and dust content of the local interstellar medium. Results of gamma-ray observations on the local interstellar medium are given. The last part is devoted to the whole of the galactic gamma-ray emission and its interpretation

  3. Study of p-wave gamma-ray strength functions

    International Nuclear Information System (INIS)

    Gamma-ray strength functions are important for description of the gamma emission channel in nuclear reactions. The impact of different models- Weisskopf's single particle model, Brink's standard Lorentzian and Kopecky's generalized Lorentzian for gamma ray strength functions on the calculation of neutron capture related experimental quantities such as total radiation widths Γγ cross sections and gamma-ray spectra has been studied

  4. Typed generic traversals in $S_gamma^'$

    NARCIS (Netherlands)

    Lämmel, R.

    2001-01-01

    A typed model of strategic rewriting is developed. An innovation is that generic traversals are covered. To this end, we define a rewriting calculus $S'_{gamma$. The calculus offers a few strategy combinators for generic traversals. There is, for example, a combinator to apply a strategy to all imme

  5. LHCb: Measurement of $A_{\\Gamma}$

    CERN Multimedia

    Smith, M

    2013-01-01

    The measurement of the time dependent CP violating observable $A_{\\Gamma}$ is presented. The result using $1fb^{-1}$ of data from pp collisions at $\\sqrt{s}=7$TeV collected in 2011 is the most accurate to date. No CP violation is observed.

  6. An empirical-parametric gamma calibration algorithm

    CERN Document Server

    Isohanni, Jani

    2014-01-01

    A method to determine the gamma correction curves for displays is presented. An empirical model is first constructed from exhaustive measurements of a few representative units. The model parameters for the remaining units are then fitted using only a few measurements. The method uses standard least-squares algorithms and is computationally light. Experimental results for a small sample of LCD displays are presented.

  7. Scaling studies with gamma transmission technique

    Energy Technology Data Exchange (ETDEWEB)

    Bjoernstad, Tor; Stamatakis, Emmanuel

    2006-03-15

    A method based on gamma transmission attenuation for study of scaling rates in open tubes has been tested and qualified in laboratory experiments. This is a non-intrusive continuous on-line technique, which requires a gamma-emitting radioactive source and a corresponding gamma detector. Gamma emission with energies larger than 300 keV from a source of {sup 133}Ba and a NaI(Tl) detector has been used in experiments with CaCO{sub 3}{sup -}scaling. The equipment allows for axial tube scanning. Thus, scaling rates and thicknesses along the length of the tube may be measured. Saturation ratios down to SR 1.5 has been tested with good results. The possibility to apply this technique to measure scaling rates also in porous media is evaluated. By optimizing the experimental conditions, scaling thicknesses down to 30 micrometer is feasible in a silicate-packed tube of 1 cm internal diameter. Besides studying induction times and scaling rates, this method is useful for screening of the effect of various scale inhibitors. (author) (tk)

  8. A Gamma Model for Mixture STR Samples

    DEFF Research Database (Denmark)

    Christensen, Susanne; Bøttcher, Susanne Gammelgaard; Morling, Niels;

    This project investigates the behavior of the PCR Amplification Kit. A number of known DNA-profiles are mixed two by two in "known" proportions and analyzed. Gamma distribution models are fitted to the resulting data to learn to what extent actual mixing proportions can be rediscovered in the amp...

  9. The new gamma-ray observatory: CTA

    Science.gov (United States)

    Carr, John

    2016-07-01

    CTA is the next generation gamma-ray observatory and will have a factor 10 better sensitivity compared to existing facilities, as well as many other superior parameters. Aspects of array layout, performance and sites are presented. The broad range of forefront science which will be studied is described.

  10. Gamma-ray emission from nova outbursts

    CERN Document Server

    Hernanz, M

    2013-01-01

    Classical novae produce radioactive nuclei which are emitters of gamma-rays in the MeV range. Some examples are the lines at 478 and 1275 keV (from 7Be and 22Na) and the positron-electron annihilation emission, with the 511 keV line and a continuum. Gamma-ray spectra and light curves are potential unique tools to trace the corresponding isotopes and to give insights on the properties of the expanding envelope. Another possible origin of gamma-rays is the acceleration of particles up to very high energies, so that either neutral pions or inverse Compton processes produce gamma-rays of energies larger than 100 MeV. MeV photons during nova explosions have not been detected yet, although several attempts have been made in the last decades; on the other hand, GeV photons from novae have been detected with the Fermi satellite in V407 Cyg, a nova in a symbiotic binary, where the companion is a red giant with a wind, instead of a main sequence star as in the cataclysmic variables hosting classical novae. Two more nov...

  11. Gamma-ray Novae: Rare or Nearby?

    CERN Document Server

    Morris, Paul J; Brown, Anthony M; Chadwick, Paula M

    2016-01-01

    Classical Novae were revealed as a surprise source of gamma-rays in Fermi LAT observations. During the first 8 years since the LAT was launched, 6 novae in total have been detected to > 5 sigma in gamma-rays, in contrast to the 69 discovered optically in the same period. We attempt to resolve this discrepancy by assuming all novae are gamma-ray emitters, and assigning peak one-day fluxes based on a flat distribution of the known emitters to a simulated population. To determine optical parameters, the spatial distribution and magnitudes of bulge and disc novae in M31 are scaled to the Milky Way, which we approximate as a disc with a 20 kpc radius and elliptical bulge with semi major axis 3 kpc and axis ratios 2:1 in the xy plane. We approximate Galactic reddening using a double exponential disc with vertical and radial scale heights of r_d = 5 kpc and z_d = 0.2 kpc, and demonstrate that even such a rudimentary model can easily reproduce the observed fraction of gamma-ray novae, implying that these apparently r...

  12. Gamma radiation decontamination of some cosmetic preparations

    International Nuclear Information System (INIS)

    the present investigation was elucidated to determine the bio burden of eye make up preparations ( intact and in-use), to isolate and identify microbial isolates from the selected cosmetic products, dose response study of the isolated microorganisms to gamma radiation and design of the sterilization dose by gamma radiation for the selected cosmetic products using the radiation resistant microorganisms. one hundred eye makeup samples (40 eye shadow samples, 35 eye mascara samples and 25 eyeliner samples) were purchased from the markets in cairo. total aerobic microbial count, isolation and identification of the microbial contaminants were performed for all the samples ( intact and in-use). gamma irradiation studies were done including dose response curves of mixed microbial population representing each company with determining their D10 values, from which the most radio resistant isolates were isolated. their D10 values together with the log of the bio-burden on the contaminated samples and a sterility assurance level of 1:10-6, were used to calculate the gamma radiation sterilization doses needed to sterilize the eye make up samples in the present study and finally sterilization doses were tested for their applicability

  13. Well logging with natural gamma radiation

    International Nuclear Information System (INIS)

    An invention is described for use in natural gamma radiation well logging in which measurements taken in a borehole are used in the search for valuable underground resources such as oil or gas. The invention comprises deriving a log of natural gamma radiation detected in selected energy windows for a selected borehole depth interval and converting it into a log of the selected subsurface materials, e.g. Th, U, K. This log is corrected for the effects of 1) either a gamma ray emitter in the borehole fluid, e.g. potassium salts and/or 2) a gamma ray attenuator in the borehole fluid, e.g. a strong attenuator such as barite and/or hematite. The Th, U, K log is particularly useful in the exploration of oil and gas resources since the Th, U, K concentrations are a good indication as to the presence, type and volume of shale and clay in the formations surrounding the borehole. (U.K.)

  14. Gamma-Ray Telescope and Uncertainty Principle

    Science.gov (United States)

    Shivalingaswamy, T.; Kagali, B. A.

    2012-01-01

    Heisenberg's Uncertainty Principle is one of the important basic principles of quantum mechanics. In most of the books on quantum mechanics, this uncertainty principle is generally illustrated with the help of a gamma ray microscope, wherein neither the image formation criterion nor the lens properties are taken into account. Thus a better…

  15. ON DIFFERENCE EQUATIONS RELATING TO GAMMA FUNCTION

    Institute of Scientific and Technical Information of China (English)

    Chen Zongxuan; Huang Zhibo; Zhang Ranran

    2011-01-01

    We consider the existence,the growth,poles,zeros,fixed points and the Borel exceptional value of solutions for the following difference equations relating to Gamma function y(z+1)-y(z) =R(z) and y(z+1) =P(z)y(z).

  16. Some Properties of Gamma Generated Distributions

    Directory of Open Access Journals (Sweden)

    Manisha Pal

    2015-12-01

    Full Text Available Based on standard probability distributions, new families of univariate distributions have been introduced and their properties studied by many authors. The present paper investigates some general properties of a family of Gamma generated distributions proposed by Zografos and Balakrishnan (2009.

  17. Effects of gamma radiation in annatto seeds

    International Nuclear Information System (INIS)

    The annatto bixin has emerged as a major source of natural dyes used in the world notably by the substitution of synthetics harmful to human health and ecologic tendency in obtaining industrial products free of additives with applications in industries textiles; cosmetics; pharmaceutical and food mainly. The aim of this research was to obtain increased of germination rate and dormancy breaking on annatto seeds by gamma radiation. Annatto dry seeds were exposed to low doses of gamma radiation from source of Cobalt-60, type Gammecell-220, at 0.456 kGy/hour dose rate. In order to study stimulation effects of radiation on germination rate and dormancy breaking in the seeds. Five treatments with gamma radiation doses were applied as follows: 0 (control); 100; 125; 150 and 175 Gy. After irradiation the annatto seeds were planted as for usual seed production. According to the results obtained in this experiment we can conclude that the low doses of gamma radiation utilized on the annatto seeds did not presented significantly effect on the germination of plants. But the best dose to increase the germination of seeds was 150 Gy. (author)

  18. The Gamma Factory proposal for CERN

    CERN Document Server

    Krasny, Mieczyslaw Witold

    2015-01-01

    This year, 2015, marks the centenary of the publication of Einsteins Theory of General Relativity and it has been named the International Year of Light and light-based technologies by the UN General Assembly. It is thus timely to discuss the possibility of broadening the present CERN research program by including a new component based on a novel concept of the light source which could pave a way towards a multipurpose Gamma Factory. The proposed light source could be realized at CERN by using the infrastructure of the existing accelerators. It could push the intensity limits of the presently operating light-sources by at least 7 orders of magnitude, reaching the flux of the order of 10^17 photons/s, in the particularly interesting gamma-ray energy domain of 1 < Ephoton < 400 MeV. This domain is out of reach for the FEL-based light sources. The energy-tuned, quasi-monochromatic gamma beams, together with the gamma-beam-driven, high intensity secondary beams of polarized positrons, polarized muons, neutro...

  19. Gamma flicker elicits positive affect without awareness

    NARCIS (Netherlands)

    B.T. Heerebout; A.E.Y Tap; M. Rotteveel; R.H. Phaf

    2013-01-01

    High-frequency oscillations emerged as a neural code for both positive affect and fluent attentional processing from evolutionary simulations with artificial neural networks. Visual 50 Hz flicker, which entrains neural oscillations in the gamma band, has been shown to foster attentional switching, b

  20. Primary shutter and gamma ray trap

    International Nuclear Information System (INIS)

    This paper reports on the main radiation shutter and gamma ray trap, which will be used at LNLS front-ends that has been designed. The components external to the UHV chamber have been assembled and are undergoing tests. Vacuum requirements for the chamber have been estimated

  1. Effects of gamma radiation in annatto seeds

    Energy Technology Data Exchange (ETDEWEB)

    Franco, Camilo F. de Oliveira, E-mail: camilo.urucum@hotmail.com [Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA/EMEPA), Joao Pessoa, PB (Brazil); Arthur, Valter; Arthur, Paula B., E-mail: arthur@cena.usp.br [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil); Harder, Marcia N.C., E-mail: marcia.harder@fatec.sp.gov.br [Centro Paula Souza, Curso Superior de Tecnologia em Bicombustiveis (FATEC), Piracicaba, SP (Brazil); Filho, Jose C.; Neto, Miguel B., E-mail: jorgecazefilho@yahoo.com.br [Empresa Estadual de Pesquisa Agropecuaria da Paraiba (EMEPA), Joao Pessoa, PB (Brazil)

    2015-07-01

    The annatto bixin has emerged as a major source of natural dyes used in the world notably by the substitution of synthetics harmful to human health and ecologic tendency in obtaining industrial products free of additives with applications in industries textiles; cosmetics; pharmaceutical and food mainly. The aim of this research was to obtain increased of germination rate and dormancy breaking on annatto seeds by gamma radiation. Annatto dry seeds were exposed to low doses of gamma radiation from source of Cobalt-60, type Gammecell-220, at 0.456 kGy/hour dose rate. In order to study stimulation effects of radiation on germination rate and dormancy breaking in the seeds. Five treatments with gamma radiation doses were applied as follows: 0 (control); 100; 125; 150 and 175 Gy. After irradiation the annatto seeds were planted as for usual seed production. According to the results obtained in this experiment we can conclude that the low doses of gamma radiation utilized on the annatto seeds did not presented significantly effect on the germination of plants. But the best dose to increase the germination of seeds was 150 Gy. (author)

  2. Technipion contribution to b --> s$\\gamma$

    CERN Document Server

    Balaji, B

    1996-01-01

    We show that the present limit on the inclusive decay b\\rightarrow s\\gamma provides strong constraints on Technicolor models. In particular, small values of F_\\pi and the mass of charged octet and singlet technipions are excluded, assuming the most natural form of the technipion coupling to the ordinary quarks.

  3. Polarization effects in collisions of. gamma. beams

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Panfil' , S.L.; Serbo, V.G.

    1983-10-01

    We study polarization effects in collisions of high energy ..gamma.. beams obtained in the Compton scattering of laser light on electrons (according to the scheme of I. F. Ginzburg et al., Preprint 81-50, IYaF SO AN SSSR, Novosibirsk, 1981, and JETP Letters 34, 491 (1982)). For this we determine the Stokes parameters of the ..gamma.. beams xi/sub i/ and xi-tilde/sub j/ and their average values and as functions of the photon energy and polarization of the initial beams. The quantities that are measurable in ..gamma gamma.. collisions are expressed in terms of the average values , which, in general, are not equal to , which complicates the study of polarization phenomena. In particular, not =0, even for unpolarized electron and laser beams. It is shown that in two important limiting cases roughly-equal. Effects due to correlation between the beams are studied.

  4. Gamma-ray bursts at high redshift

    NARCIS (Netherlands)

    R.A.M.J. Wijers

    1999-01-01

    Gamma-ray bursts are much brighter than supernovae, and could therefore possibly probe the Universe to high redshift. The presently established GRB redshifts range from 0.83 to 5, and quite possibly even beyond that. Since most proposed mechanisms for GRB link them closely to deaths of massive stars

  5. Neutrino Balls and Gamma-Ray Bursts

    CERN Document Server

    Holdom, B

    1994-01-01

    We propose a mechanism by which the neutrino emission from a supernova-type explosion can be converted into a gamma-ray burst of total energy $\\sim 10^{50}$ ergs. This occurs naturally if the explosion is situated inside a ball of trapped neutrinos, which in turn may lie at a galactic core. There are possible unique signatures of this scenario.

  6. Gamma Ray Imaging for Environmental Remediation

    Energy Technology Data Exchange (ETDEWEB)

    B.F. Philips; R.A. Kroeger: J.D. Kurfess: W.N. Johnson; E.A. Wulf; E. I. Novikova

    2004-11-12

    This program is the development of germanium strip detectors for environmental remediation. It is a collaboration between the Naval Research Laboratory and Lawrence Berkeley National Lab. The goal is to develop detectors that are simultaneously capable of excellent spectroscopy and imaging of gamma radiation.

  7. Inactivation of RNA viruses by gamma irradiation

    International Nuclear Information System (INIS)

    Four kinds of RNA viruses, Bluetongue virus (BT), Bovine Virus Diarrhea-Mucosal Disease virus (BVD·MD), Bovine Respiratory Syncytial virus (RS), Vesicular Stmatitis virus (VS), were subjected to various doses of gamma irradiation to determine the lethal doses. The D10 values, which are the dose necessary to decimally reduce infectivity, ranged from 1.5 to 3.4 kGy under frozen condition at dry-ice temperature, and they increased to 2.6 to 5.0 kGy under frozen condition at dry-ice temperature. Serum neutralzing antibody titer of Infectious Bovine Rhinotracheitis (IBR) was not adversely changed by the exposure to 36 kGy of gamma-rays under frozen condition. Analysis of electrophoresis patterns of the bovine serum also reveales that the serum proteins were not remarkably affected, even when exposed to 36 kGy of gamma radiation under frozen condition. The results suggested that gamma irradiation under frozen condition is an effective means for inactivating both DNA and RNA viruses without adversely affecting serum proteins and neutralizing antibody titer. (author)

  8. Synthesis of alkylfurans from. gamma. -oxoaldehydes. gamma. -oxoaldehyde wo genryotosuru alkylfuran rui no gosei

    Energy Technology Data Exchange (ETDEWEB)

    Tsukasa, H. (Toyotama Perfumery, Co. Ltd., Tokyo (Japan))

    1991-06-20

    2-Alkyl 3-or 4-methy1 furans and 2-alkylfurans, which are compounds naturally produced, were synthesized from {gamma}-oxoaldehydes or {gamma}-oxoaldehyde acetals. 3-Methyl-4-oxoaldehydes were synthesized in 48 to 60% yields from aliphatic aldehyde and crotonaldehyde through a radical addition reaction. Treatment of {gamma}-oxoaldehydes with pyrophosphoric acid in benzene under reflux with the azeotropic removal of water gave alkylfurans in 3 to 42% yields. Alkylfurans were also obtained in 35 to 78% yields through the dropwise addition of {gamma}-oxoaldehyde acetal under reduced pressure. Futhermore, menthofurans, which are a minor but important olfactive ingredient of peppermint oil, were obtained in a 64% yield from 9,10-epoxy-3,3-ethylenedioxy-p-menthane. 15 refs., 2 tabs.

  9. Competing $\\gamma$-rigid and $\\gamma$-stable vibrations in neutron rich Gd and Dy isotopes

    CERN Document Server

    Budaca, R

    2015-01-01

    An exactly separable version of the Bohr Hamiltonian which combines the $\\gamma$-stable and $\\gamma$-rigid axial vibration-rotation is used to describe the collective properties of few neutron rich transitional nuclei. The coupling between the two types of collective motion is managed through a rigidity parameter which also influences the geometry of the shape-phase space. While the $\\gamma$-angular part of the problem associated to axially symmetric shapes is treated within the small angles approximation and the stiff $\\gamma$ oscillation hypothesis, the $\\beta$ vibration is described by means of a Davidson potential. The resulting model have three free parameters not counting the scale and was successfully applied for the description of the collective spectra for few heavier isotopes of Gd and Dy. In both cases a critical nucleus was identified through a discontinuous behavior in respect to the rigidity parameter and relevant experimental observables.

  10. Exploring anomalous $HZ\\gamma $ couplings in $\\gamma $-proton collisions at the LHC

    CERN Document Server

    Monfared, S Taheri; Najafabadi, M Mohammadi

    2016-01-01

    The $HZ\\gamma $ coupling, which is highly sensitive to the new physics beyond the standard model, is studied through the process $pp\\rightarrow p\\gamma p\\rightarrow pHX$ at the LHC. To this purpose, an effective Lagrangian, in a model independent approach, with dimension six operators is considered in this paper. New interaction terms regarding beyond the standard model physics include the Higgs boson anomalous vertices in both CP-even and CP-odd structures. A detailed numerical analysis is performed to scrutinize the accurate constraints on the effective $HZ\\gamma $ couplings and to discuss how far the corresponding bounds can be improved. This is achieved by testing all the efficient Higgs decay channels and increasing the integrated luminosity at three different forward detector acceptance regions. The numerical results propose that the Higgs photoproduction at the LHC, as a complementary channel, has a great potential of exploring the $HZ\\gamma $ couplings.

  11. Systematic Study of Gamma-ray bright Blazars with Optical Polarization and Gamma-ray Variability

    CERN Document Server

    Itoh, Ryosuke; Fukazawa, Yasushi; Uemura, Makoto; Tanaka, Yasuyuki T; Kawabata, Koji S; Madejski, Grzegorz M; Schinzel, Frank K; Kanda, Yuka; Shiki, Kensei; Akitaya, Hiroshi; Kawabata, Miho; Moritani, Yuki; Nakaoka, Tatsuya; Ohsugi, Takashi; Sasada, Mahito; Takaki, Katsutoshi; Takata, Koji; Ui, Takahiro; Yamanaka, Masayuki; Yoshida, Michitoshi

    2016-01-01

    Blazars are highly variable active galactic nuclei which emit radiation at all wavelengths from radio to gamma-rays. Polarized radiation from blazars is one key piece of evidence for synchrotron radiation at low energies and it also varies dramatically. The polarization of blazars is of interest for understanding the origin, confinement, and propagation of jets. However, even though numerous measurements have been performed, the mechanisms behind jet creation, composition and variability are still debated. We performed simultaneous gamma-ray and optical photopolarimetry observations of 45 blazars between Jul. 2008 and Dec. 2014 to investigate the mechanisms of variability and search for a basic relation between the several subclasses of blazars. We identify a correlation between the maximum degree of optical linear polarization and the gamma-ray luminosity or the ratio of gamma-ray to optical fluxes. Since the maximum polarization degree depends on the condition of the magnetic field (chaotic or ordered), thi...

  12. Final Results from the KTeV Experiment on the Decay KL -> pi0 gamma gamma

    CERN Document Server

    Abouzaid, E; Barker, A R; Bellantoni, L; Blucher, E; Bock, G J; Cheu, E; Coleman, R; Corcoran, M D; Cox, B; Erwin, A R; Escobar, C O; Glazov, A; Golossanov, A; Gomes, R A; Gouffon, P; Hsiung, Y B; Jensen, D A; Kessler, R; Kotera, K; Ledovskoy, A; McBride, P L; Monnier, E; Nguyen, H; Niclasen, R; Phillips, D G; Ramberg, E J; Ray, R E; Ronquest, M; Santos, E; Slater, W; Smith, D; Solomey, Nickolas; Swallow, E C; Toale, P A; Tschirhart, R; Wah, Y W; Wang, J; White, H B; Whitmore, J; Wilking, M J; Winstein, B; Winston, R; Worcester, E T; Yamanaka, T; Zimmerman, E D; Zukanovich-Funchal, R

    2008-01-01

    We report on a new measurement of the branching ratio B(KL->pi0 gamma gamma)using the KTeV detector. We reconstruct 1982 events with an estimated background of 608, that results in B(KL -> pi0 gamma gamma) = (1.29 +/- 0.03(stat) +/- 0.05(syst)) x 10**-6. We also measure the parameter, aV, which characterizes the strength of vector meson exchange terms in this decay. We find aV = -0.31 +/- 0.05(stat) +/- 0.07(syst). These results utilize the full KTeV data set collected from 1997 to 2000 and supersede earlier KTeV measurements of the branching ratio and aV.

  13. On the maximum and minimum of two modified Gamma-Gamma variates with applications

    KAUST Repository

    Al-Quwaiee, Hessa

    2014-04-01

    In this work, we derive the statistical characteristics of the maximum and the minimum of two modified1 Gamma-Gamma variates in closed-form in terms of Meijer\\'s G-function and the extended generalized bivariate Meijer\\'s G-function. Then, we rely on these new results to present the performance analysis of (i) a dual-branch free-space optical selection combining diversity undergoing independent but not necessarily identically distributed Gamma-Gamma fading under the impact of pointing errors and of (ii) a dual-hop free-space optical relay transmission system. Computer-based Monte-Carlo simulations verify our new analytical results.

  14. Capability of analysis arsenic in geology sample by gamma-gamma coincidence method

    International Nuclear Information System (INIS)

    Gamma-gamma coincidence method has been successfully applied to the study of nuclear data and structure. Due to good abilities of background reduction, gamma-gamma coincidence method has been widely applied in neutron activation analysis. The experimental studies on geological and environmental samples have been conducted in several laboratories in the world. This report presents the results of Arsenic (As) analysis of geological sample by neutron activation analysis with coincidence method. The results show that the linearity between concentration in sample and count rate of peak in coincidence measurements and the influence of isotopes was eliminated and the background was reduced by application of this method in comparison with the conventional method that uses a detector. The results also found out that detection limits for analysis of As in geological samples were improved. (author)

  15. Measuring the charged pion polarizability in the gamma gamma -> pi+pi- reaction

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, David W. [JLAB; Miskimen, Rory A. [University of Massachusetts, Amherst; Mushkarenkov, Alexander Nikolaevich [University of Massachusetts, Amherst; Smith, Elton S. [JLAB

    2013-08-01

    Development has begun of a new experiment to measure the charged pion polarizability $\\alpha_{\\pi}-\\beta_{\\pi}$. The charged pion polarizability ranks among the most important tests of low-energy QCD presently unresolved by experiment. Analogous to precision measurements of $\\pi^{\\circ}\\rightarrow\\gamma\\gamma$ that test the intrinsic odd-parity (anomalous) sector of QCD, the pion polarizability tests the intrinsic even-parity sector of QCD. The measurement will be performed using the $\\gamma\\gamma\\rightarrow\\pi^{+{}}\\pi^{-{}}$ cross section accessed via the Primakoff mechanism on nuclear targets using the GlueX detector in Hall D at Jefferson Lab. The linearly polarized photon source in Hall-D will be utilized to separate the Primakoff cross-section from coherent $\\rho^{\\circ}$ production.

  16. $H\\rightarrow \\gamma\\gamma$ as a Triangle Anomaly: Possible Implications for the Hierarchy Problem

    CERN Document Server

    de Gouvea, Andre; Vega-Morales, Roberto

    2013-01-01

    The Standard Model calculation of $H\\rightarrow\\gamma\\gamma$ has the curious feature of being finite but regulator-dependent. While dimensional regularization yields a result which respects the electromagnetic Ward identities, additional terms which violate gauge invariance arise if the calculation is done setting $d=4$. This discrepancy between the $d=4-\\epsilon$ and $d=4$ results is recognized as a true ambiguity which must be resolved using physics input; as dimensional regularization respects gauge invariance, the $d=4-\\epsilon$ calculation is accepted as the correct SM result. However, here we point out another possibility; working in analogy with the gauge chiral anomaly, we note that it is possible that the individual diagrams do violate the electromagnetic Ward identities, but that the gauge-invariance-violating terms cancel when all contributions to $H\\rightarrow\\gamma\\gamma$, both from the SM and from new physics, are included. We thus examine the consequences of the hypothesis that the $d=4$ calcul...

  17. Managing $\\gamma_5$ in Dimensional Regularization II: the Trace with more $\\gamma_5$

    CERN Document Server

    Ferrari, Ruggero

    2015-01-01

    In the present paper we evaluate the anomaly for the abelian axial current in a non abelian chiral gauge theory, by using dimensional regularization. This amount to formulate a procedure for managing traces with more than one $\\gamma_5$. \\par The suggested procedure obeys Lorentz covariance and cyclicity, at variance with previous approaches (e.g. the celebrated 't Hooft and Veltman's where Lorentz is violated) \\par The result of the present paper is a further step forward in the program initiated by a previous work on the traces involving a single $\\gamma_5$. The final goal is an unconstrained definition of $\\gamma_5$ in dimensional regularization. Here, in the evaluation of the anomaly, we profit of the axial current conservation equation, when radiative corrections are neglected. This kind of tool is not always exploited in field theories with $\\gamma_5$, e.g. in the use of dimensional regularization of infrared and collinear divergences.

  18. Modeling and simulation of gamma camera

    International Nuclear Information System (INIS)

    Simulation techniques play a vital role in designing of sophisticated instruments and also for the training of operating and maintenance staff. Gamma camera systems have been used for functional imaging in nuclear medicine. Functional images are derived from the external counting of the gamma emitting radioactive tracer that after introduction in to the body mimics the behavior of native biochemical compound. The position sensitive detector yield the coordinates of the gamma ray interaction with the detector and are used to estimate the point of gamma ray emission within the tracer distribution space. This advanced imaging device is thus dependent on the performance of algorithm for coordinate computing, estimation of point of emission, generation of image and display of the image data. Contemporary systems also have protocols for quality control and clinical evaluation of imaging studies. Simulation of this processing leads to understanding of the basic camera design problems. This report describes a PC based package for design and simulation of gamma camera along with the options of simulating data acquisition and quality control of imaging studies. Image display and data processing the other options implemented in SIMCAM will be described in separate reports (under preparation). Gamma camera modeling and simulation in SIMCAM has preset configuration of the design parameters for various sizes of crystal detector with the option to pack the PMT on hexagon or square lattice. Different algorithm for computation of coordinates and spatial distortion removal are allowed in addition to the simulation of energy correction circuit. The user can simulate different static, dynamic, MUGA and SPECT studies. The acquired/ simulated data is processed for quality control and clinical evaluation of the imaging studies. Results show that the program can be used to assess these performances. Also the variations in performance parameters can be assessed due to the induced

  19. BL Lacertae Objects and the Extragalactic Gamma-Ray Background

    CERN Document Server

    Li, Fan

    2011-01-01

    A tight correlation between gamma-ray and radio emission is found for a sample of BL Lacertae (BL Lac) objects detected by Fermi Gamma-ray Space Telescope (Fermi) and the Energetic Gamma-Ray Experiment Telescope (EGRET). The gamma-ray emission of BL Lac objects exhibits strong variability, and the detection rate of gamma-ray BL Lac objects is low, which may be related to the gamma-ray duty cycle of BL Lac objects. We estimate the gamma-ray duty cycle ~ 0.11, for BL Lac objects detected by EGRET and Fermi. Using the empirical relation of gamma-ray emission with radio emission and the estimated gamma-ray duty cycle, we derive the gamma-ray luminosity function (LF) of BL Lac objects from their radio LF. Our derived gamma-ray LF of BL Lac objects can almost reproduce that calculated with the recently released Fermi bright active galactic nuclei (AGN) sample. We find that about 45% of the extragalactic diffuse gamma-ray background (EGRB) is contributed by BL Lac objects. Combining the estimate of the quasar contri...

  20. Albedo method applied to coupled neutron-gamma shielding radiations

    International Nuclear Information System (INIS)

    The Albedo Theory was applied in order to develop an one-group algorithm for coupled neutron-gamma shielding calculations. The configuration analyzed consists of multilayered plane systems, where a incident neutron current generates gamma radiation through neutron-gamma reactions. The results obtained by Albedo Method and ANISN code have shown excellent agreement. (author)