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Sample records for brusselaers stam monstrey

  1. NIMS and Empa announce STAM collaboration

    Science.gov (United States)

    Yoshida, Toyonobu; Krug, Harald F.

    2014-02-01

    In January 2014, the Swiss Federal Laboratories for Materials Science and Technology (Empa) joined the National Institute for Materials Science (NIMS) in collaborative activities on Science and Technology of Advanced Materials (STAM). STAM was founded in 2000. In 2005 NIMS took over the management of its peer review and financial systems, resulting in a continuous rise of the impact of the journal. Empa will provide further support for the editorial management of STAM. In particular, it will establish a European office in Switzerland and reinforce the Editorial Board. From this point of view, I am pleased and excited to have new colleagues from Empa on our Editorial Board, and I believe that this collaboration will bring us a remarkable improvement in the international visibility of STAM and increase the number of paper submissions from Europe. It will expand the topics covered in the journal from traditional fields of materials science with a focus on energy and environmental issues to medical and bioengineering applications, where Empa has a significant expertise. I firmly believe that Empa's participation in publishing STAM will reinforce its position as an open-access journal with a global audience. Together with my colleagues, Yoshio Sakka (NIMS) and Shu Yamaguchi (University of Tokyo), I welcome Harald F Krug as the new Co-Editor-in-Chief of STAM. I am also pleased to learn that the year 2014 not only marks the 15th anniversary of STAM, but also the 150th anniversary of the establishment of diplomatic relations between Japan and Switzerland. Toyonobu Yoshida Advances in materials science are key for the sustainable development of our society. That is why, starting from January 2014, Empa, the Swiss Federal Laboratories for Materials Science and Technology, have engaged in an entirely new field of activity: scientific publishing. As mentioned above, Empa joined NIMS in the publishing of STAM. We have a clear-cut goal in mind: we want to support our sister

  2. EDITORIAL: STAM celebrates its 10th anniversary STAM celebrates its 10th anniversary

    Science.gov (United States)

    Ushioda, Sukekatsu

    2010-02-01

    I would like to extend my warmest greetings to the readers and staff of Science and Technology of Advanced Materials (STAM), on the occasion of its 10th anniversary. Launched in 2000, STAM marks this year an important milestone in its history. This is a great occasion to celebrate. STAM was founded by Tsuyoshi Masumoto in collaboration with Teruo Kishi and Toyonobu Yoshida as a world-class resource for the materials science community. It was initially supported by several materials research societies and was published as a regular peer-reviewed journal. Significant changes occurred in 2008, when the National Institute for Materials Science (NIMS) became solely responsible for all the costs of maintaining the journal. STAM was transformed into an open-access journal published by NIMS in partnership with IOP Publishing. As a result, the publication charges were waived and the entire STAM content, including all back issues, became freely accessible through the IOP Publishing website. The transition has made STAM more competitive and successful in global publication communities, with innovative ideas and approaches. The journal has also changed its publication strategy, aiming to publish a limited number of high-quality articles covering the frontiers of materials science. Special emphasis has been placed on reviews and focus issues, providing recent summaries of hot materials science topics. Publication has become electronic only; however, selected issues are printed and freely distributed at major international scientific events. The Editorial Board has been expanded to include leading experts from all over the world and, together with the Editorial Office, the board members are doing their best to transform STAM into a leading materials science journal. These efforts are paying off, as shown by the rapidly increasing number of article downloads and citations in 2009. I believe that the STAM audience can not only deepen their knowledge in their own specialties but

  3. Gerontechnology acceptance by elderly Hong Kong Chinese: a senior technology acceptance model (STAM).

    Science.gov (United States)

    Chen, Ke; Chan, Alan Hoi Shou

    2014-01-01

    The purpose of this study was to develop and test a senior technology acceptance model (STAM) aimed at understanding the acceptance of gerontechnology by older Hong Kong Chinese people. The proposed STAM extended previous technology acceptance models and theories by adding age-related health and ability characteristics of older people. The proposed STAM was empirically tested using a cross-sectional questionnaire survey with a sample of 1012 seniors aged 55 and over in Hong Kong. The result showed that STAM was strongly supported and could explain 68% of the variance in the use of gerontechnology. For older Hong Kong Chinese, individual attributes, which include age, gender, education, gerontechnology self-efficacy and anxiety, and health and ability characteristics, as well as facilitating conditions explicitly and directly affected technology acceptance. These were better predictors of gerontechnology usage behaviour (UB) than the conventionally used attitudinal factors (usefulness and ease of use).

  4. Brasil, estudos pós-coloniais e contracorrentes análogas: entrevista com Ella Shohat e Robert Stam

    NARCIS (Netherlands)

    dos Santos, E.R.S.; Schor, P.

    2013-01-01

    Interview with Ella Shohat and Robert Stam (Portuguese translation). Original version: Brazil is not Traveling Enough”: On Postcolonial Theory and Analogous Counter-Currents (http://www2.let.uu.nl/solis/psc/P/PVOLUMEFOUR/PVOLUMEFOURPAPERS/P4SHOHAT-STAM-INTERVIEW.pdf)

  5. The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development.

    Directory of Open Access Journals (Sweden)

    Hélène Chanut-Delalande

    Full Text Available BACKGROUND: Endocytosis is a key regulatory step of diverse signalling pathways, including receptor tyrosine kinase (RTK signalling. Hrs and Stam constitute the ESCRT-0 complex that controls the initial selection of ubiquitinated proteins, which will subsequently be degraded in lysosomes. It has been well established ex vivo and during Drosophila embryogenesis that Hrs promotes EGFR down regulation. We have recently isolated the first mutations of stam in flies and shown that Stam is required for air sac morphogenesis, a larval respiratory structure whose formation critically depends on finely tuned levels of FGFR activity. This suggest that Stam, putatively within the ESCRT-0 complex, modulates FGF signalling, a possibility that has not been examined in Drosophila yet. PRINCIPAL FINDINGS: Here, we assessed the role of the Hrs/Stam complex in the regulation of signalling activity during Drosophila development. We show that stam and hrs are required for efficient FGFR signalling in the tracheal system, both during cell migration in the air sac primordium and during the formation of fine cytoplasmic extensions in terminal cells. We find that stam and hrs mutant cells display altered FGFR/Btl localisation, likely contributing to impaired signalling levels. Electron microscopy analyses indicate that endosome maturation is impaired at distinct steps by hrs and stam mutations. These somewhat unexpected results prompted us to further explore the function of stam and hrs in EGFR signalling. We show that while stam and hrs together downregulate EGFR signalling in the embryo, they are required for full activation of EGFR signalling during wing development. CONCLUSIONS/SIGNIFICANCE: Our study shows that the ESCRT-0 complex differentially regulates RTK signalling, either positively or negatively depending on tissues and developmental stages, further highlighting the importance of endocytosis in modulating signalling pathways during development.

  6. Expression pattern and functional analysis of mouse Stam2 in the olfactory system.

    Science.gov (United States)

    Furić Cunko, Vesna; Mitrecić, Dinko; Mavrić, Sandra; Gajović, Srećko

    2008-01-01

    Gene trap mutant mice Stam(gt1Gaj) were investigated in order to elucidate in vivo function of Stam2 (signal transducing adaptor molecule 2) gene, which was in vitro implicated in sorting cargo marked by monoubiquitination toward degradation in the lysosomes. The expression analysis showed high Stam2 expression in the brain including the regions related to olfaction, and in the olfactory epithelium, but not in the respiratory part of nasal mucosa. To test mouse olfaction, ability to find chocolate hidden under the sawdust in the cage was examined. When food was given ad libitum before trials, mutants needed more time and failed more frequently to find the chocolate. In contrast, when the mice were fasted overnight before trial, there were no differences between mutants and wild type mice. No changes in morphology of olfactory mucosa were observed. The obtained results showed the existence of phenotype differences between mutants and wild type mice. However, different results of two approaches aimed to test olfaction, with and without food deprivation, currently do not enable to assign the particular function of Stam2 to olfaction. This emphasizes how slight modification of experimental setup in behavioural testing can cause important differences on the obtained results.

  7. STAM protocol in dementia: a multicenter, single-blind, randomized, and controlled trial.

    Science.gov (United States)

    Ceccato, Enrico; Vigato, Giovanna; Bonetto, Chiara; Bevilacqua, Albina; Pizziolo, Paolo; Crociani, Susanna; Zanfretta, Emanuele; Pollini, Lorenza; Caneva, Paolo Alberto; Baldin, Lorella; Frongillo, Cristina; Signorini, Andrea; Demoro, Sara; Barchi, Elisabetta

    2012-08-01

    The Sound Training for Attention and Memory in Dementia (STAM-Dem) is a manualized music-based protocol designed to be used in the rehabilitation of cognitive functions in elderly patients with dementia (PWD). This was a multicenter, single-blind, randomized, and controlled trial that involved 51 PWD. The objective was to test the STAM-Dem efficacy. Patients in the experimental group followed the STAM-Dem for 2 weekly sessions of 45 minutes for 12 weeks (in addition to standard care). Those in the control group continued with the normal "standard care" provided. In the experimental group, the instruments immediate prose memory test (MPI), deferred prose memory test (MPD), attentional matrices, activities of daily living, Music Therapy Activity Scale (SVAM) and Geriatric Music Therapy Profile (GMP) increase significantly from pre to post-test (P effect on attentino (matrices) and prose memory skills (MPI and MPD). The effect size reveals a general improvement in the results of the experimental group.

  8. On Generalized Stam Inequalities and Fisher–Rényi Complexity Measures

    Directory of Open Access Journals (Sweden)

    Steeve Zozor

    2017-09-01

    Full Text Available Information-theoretic inequalities play a fundamental role in numerous scientific and technological areas (e.g., estimation and communication theories, signal and information processing, quantum physics, … as they generally express the impossibility to have a complete description of a system via a finite number of information measures. In particular, they gave rise to the design of various quantifiers (statistical complexity measures of the internal complexity of a (quantum system. In this paper, we introduce a three-parametric Fisher–Rényi complexity, named ( p , β , λ -Fisher–Rényi complexity, based on both a two-parametic extension of the Fisher information and the Rényi entropies of a probability density function ρ characteristic of the system. This complexity measure quantifies the combined balance of the spreading and the gradient contents of ρ , and has the three main properties of a statistical complexity: the invariance under translation and scaling transformations, and a universal bounding from below. The latter is proved by generalizing the Stam inequality, which lowerbounds the product of the Shannon entropy power and the Fisher information of a probability density function. An extension of this inequality was already proposed by Bercher and Lutwak, a particular case of the general one, where the three parameters are linked, allowing to determine the sharp lower bound and the associated probability density with minimal complexity. Using the notion of differential-escort deformation, we are able to determine the sharp bound of the complexity measure even when the three parameters are decoupled (in a certain range. We determine as well the distribution that saturates the inequality: the ( p , β , λ -Gaussian distribution, which involves an inverse incomplete beta function. Finally, the complexity measure is calculated for various quantum-mechanical states of the harmonic and hydrogenic systems, which are the two main

  9. High-resolution solid-state 13C NMR spectroscopy of the paramagnetic metal-organic frameworks, STAM-1 and HKUST-1.

    Science.gov (United States)

    Dawson, Daniel M; Jamieson, Lauren E; Mohideen, M Infas H; McKinlay, Alistair C; Smellie, Iain A; Cadou, Romain; Keddie, Neil S; Morris, Russell E; Ashbrook, Sharon E

    2013-01-21

    Solid-state (13)C magic-angle spinning (MAS) NMR spectroscopy is used to investigate the structure of the Cu(II)-based metal-organic frameworks (MOFs), HKUST-1 and STAM-1, and the structural changes occurring within these MOFs upon activation (dehydration). NMR spectroscopy is an attractive technique for the investigation of these materials, owing to its high sensitivity to local structure, without any requirement for longer-range order. However, interactions between nuclei and unpaired electrons in paramagnetic systems (e.g., Cu(II)-based MOFs) pose a considerable challenge, not only for spectral acquisition, but also in the assignment and interpretation of the spectral resonances. Here, we exploit the rapid T(1) relaxation of these materials to obtain (13)C NMR spectra using a spin-echo pulse sequence at natural abundance levels, and employ frequency-stepped acquisition to ensure uniform excitation of resonances over a wide frequency range. We then utilise selective (13)C isotopic labelling of the organic linker molecules to enable an unambiguous assignment of NMR spectra of both MOFs for the first time. We show that the monomethylated linker can be recovered from STAM-1 intact, demonstrating not only the interesting use of this MOF as a protecting group, but also the ability (for both STAM-1 and HKUST-1) to recover isotopically-enriched linkers, thereby reducing significantly the overall cost of the approach.

  10. Theory to practice: A study of science teachers' pedagogical practices as measured by the Science Teacher Analysis Matrix (STAM) and Teacher Pedagogical Philosophy Interview (TPPI)

    Science.gov (United States)

    Brown, Sherri Lynne

    This study continued research previously conducted by a nine-university collaborative, the Salish I Research Project, by exploring science teachers' beliefs and actions with regard to inquiry instruction. Science education reform efforts require that students learn science via inquiry. The purpose of this study was to determine and classify espoused teaching beliefs and observable teaching style. Reported are linkages between the teachers' beliefs and styles, influential coursework from College of Education and College of Liberal Arts, and outcomes of increased classroom experience. Eight participants were chosen from three separate preservice science education cohorts. Inquiry efforts require a student-centered environment as opposed to the traditional teacher-centered environment. According to the 1997 Salish I Research Collaborative, beginning teachers displayed a stark contrast between their student centered beliefs to their teacher-centered actions. The limitations of this study were as follows: (1) the participants had completed the authentic research-based inquiry science course, Knowing and Teaching Science: Just Do It; (2) the participants were currently teaching science at the secondary level; (3) the selected instruments were used in the Salish I Research Collaborative Study, and (4) instrument validity and reliability data were not available. Interview data from the Teacher Pedagogical Philosophy Interview (TPPI) instrument and observational data from the Secondary Science Teacher Analysis Matrix (STAM) instrument were statistically compiled via concept maps and matrices. Data were then represented on an ordinal scale. Interview results indicated that 87.5% of the participants professed a teacher-centered style with regard to teacher and student's actions. Observational results indicated that 56% of the participants displayed a teacher-centered style with regard to content, teacher's actions, student's actions, resources, and environment. Additionally

  11. Enerģijas dzērienu zīmolu atpazīstamība un lojalitāte: Red Bull, Shark un Burn gadījums

    OpenAIRE

    Vaņkova, Lauma

    2011-01-01

    Bakalaura darba nosaukums ir „Enerģijas dzērienu zīmolu atpazīstamība un lojalitāte: Red Bull, Shark un Burn gadījums.” Darba mērķis ir noskaidrot, cik informēta ir jauniešu auditorija par Latvijā pieejamiem enerģijas dzērienu zīmoliem, kā arī noskaidrot iemeslus, kādēļ viņi izvēlas konkrētos zīmolus. Darba teorētiskajā daļā tiek apskatīta teorija par zīmola jēdzienu un funkcijām, zīmolvedību, kā arī zīmola komunikācijas aspektiem, un, pamatojoties uz teorētiskajām nostādnēm, tiek analizē...

  12. LIVE RĪGA zīmola komunikācija: atpazīstamība, uztvere un attieksme iekšējā publikā

    OpenAIRE

    2010-01-01

    Šī bakalaura darba mērķis ir izpētīt iekšējās publikas zīmola uztveri, atpazīstamību un attieksmi pret Rīgas tūrismu veicinoša zīmola LIVE RĪGA komunicēto zīmola identitāti, tās elementiem un vērtībām. Darba teorētiskajā daļā tiek apkopota literatūra par zīmola, zīmola vadīšanas pamataspektiem, zīmola identitāti un tēlu, zīmola asociācijām un zīmola komunikāciju. Galvenokārt teorijas daļā tika iekļautas tādu autoru kā Deivida Ākera, Žana-Noela Kapferera, Kevina Kellera un Filipa Kotlera, kā a...

  13. Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways

    DEFF Research Database (Denmark)

    Pandey, A; Fernandez, M M; Steen, H;

    2000-01-01

    In an effort to clone novel tyrosine-phosphorylated substrates of the epidermal growth factor receptor, we have initiated an approach coupling affinity purification using anti-phosphotyrosine antibodies to mass spectrometry-based identification. Here, we report the identification of a signaling m...

  14. Videi un cilvēka veselībai bīstamās vielas plaša patēriņa produktu grupās

    OpenAIRE

    Meija-Toropova, Agnese

    2013-01-01

    Maģistra darbā apskatīta cilvēka veselībai un apkārtējai videi bīstamo vielu saturošo plaša patēriņa produktu pārvaldības problemātika, kā arī ar to saistītie iedzīvotāju informētības jautājumi. Darbā ar literatūras, produktu drošības datu lapu, kā arī iedzīvotāju viedokļu analīzes palīdzību apkopota informācija par atsevišķās plaša patēriņa produktu grupās visbiežāk sastopamajām bīstamajām vielām, to potenciālajiem iedarbības efektiem un pircēju izvēli noteicošajiem faktoriem, kā arī izdarīt...

  15. The double dissociation of phenomenological and experimental methods in psychology; a case study

    NARCIS (Netherlands)

    van Hezewijk, René; Stam, Henderikus; Panhuysen, Geert

    2010-01-01

    In the nineteen sixties The Utrecht School became famous for its contributions to phenomenological psychology (Van Hezewijk, Stam, & Panhuysen, 2002) (see also the preceding papers in this conference by H. Stam). In this paper we will try to present the view we arrived at in our research on how

  16. De ontogenese van de darm bij Mus musculus L.

    NARCIS (Netherlands)

    Pleeging, Johannes Hermanus

    1975-01-01

    Een onderzoek werd verricht naar de ontwikkeling van de darm bij de muis (Mus Musculus L, stam C57 BL/RIJ en stam C57 BL/OSCN), aan embryonen van opeenvolgende leeftijden. Hiertoe werden van de maagdarmtractus van de embryonen 8 tot 16,5 dag p.c. reconstructies vervaardigd. Enige waarnemingen werden

  17. PTP1B targets the endosomal sorting machinery

    DEFF Research Database (Denmark)

    Stuible, Matthew; Abella, Jasmine V; Feldhammer, Matthew;

    2010-01-01

    STAM2 specifically suppressed Akt activation, and a phosphorylation-deficient STAM2 mutant displayed prolonged localization on endosomes following EGF stimulation. These results reveal a novel link between the dephosphorylation and endocytic machinery and suggest that PTP1B can affect RTK signaling...

  18. Double-edged sword of interdisciplinary knowledge flow from hard sciences to humanities and social sciences: Evidence from China.

    Science.gov (United States)

    Liu, Meijun; Shi, Dongbo; Li, Jiang

    2017-01-01

    Humanities and Social Sciences (HSS) increasingly absorb knowledge from Hard Sciences, i.e., Science, Technology, Agriculture and Medicine (STAM), as testified by a growing number of citations. However, whether citing more Hard Sciences brings more citations to HSS remains to be investigated. Based on China's HSS articles indexed by the Web of Science during 1998-2014, this paper estimated two-way fixed effects negative binomial models, with journal effects and year effects. Findings include: (1) An inverse U-shaped curve was observed between the percentage of STAM references to the HSS articles and the number of citations they received; (2) STAM contributed increasing knowledge to China's HSS, while Science and Technology knowledge contributed more citations to HSS articles. It is recommended that research policy should be adjusted to encourage HSS researchers to adequately integrate STAM knowledge when conducting interdisciplinary research, as over-cited STAM knowledge may jeopardize the readability of HSS articles.

  19. Collaborative study with reference materials containing Clostridium perfringens (strain D10) for water microbiology

    NARCIS (Netherlands)

    Manavakis M; van Dommelen JA; Mooijman KA; Havelaar AH; LWL

    1995-01-01

    In december 1993 werd een internationaal ringonderzoek voor watermicrobiologische laboratoria georganiseerd om een nieuw ontwikkeld referentiemateriaal met Clostridium perfringens (stam D10) uit te testen. Aan dit ringonderzoek namen 24 Europese laboratoria deel. Elk laboratorium testte 8 capsules

  20. Application of mixed models for the assessment genotype and ...

    African Journals Online (AJOL)

    SAM

    2014-05-07

    May 7, 2014 ... In the process of introducing cotton cultivars, it is essential to assess their productive ... In turn, the cultivars CA 222, STAM 42 and ISA-205 were ..... sector development in Mozambique. ... Principles of genetics quantitative.

  1. Editorial

    Science.gov (United States)

    Yoshida, Toyonobu

    2013-02-01

    As the successor to Professor Teruo Kishi, the former Editor-in-Chief of Science and Technology of Advanced Materials (STAM), I would like to share some of STAM's journal history with our readers. STAM was launched in 2000 with the financial support of the Japanese Ministry of Education, Culture, Sports, Science and Technology in recognition of a strong need for an international journal that would be distributed and read across the globe. Five years later, the publication of STAM was transferred to the National Institute for Materials Science (NIMS) under the initiative of Professor Kishi. As a result of his work, STAM is now positioned as a high-impact journal, 3.512 as listed by the ISI 2011 Science Citation Index Journal Citation Report, with a much higher and faster growth than when I was participating as a co-founder in the past. STAM is well known as a successful open-access journal since shifting from the initial subscription model in 2008. As an editor, I would like to emphasize that STAM will continue to publish with a sense of social mission as an academic journal, allowing space for researchers to contribute to the sustainable development of society and health. However, some contribution from authors would assist us in creating a sustainable journal publishing model, and further enhance services to authors and readers of STAM. With this in mind, I would like to state that STAM's editorial board is planning to introduce an article processing charge from July 2013, in addition to NIMS' continuing financial support. One of our new editorial policies is to aim for reader-oriented publishing. I believe that academic journal publishing can take the role of navigator in advancing the development of materials. Among the many other scientific journals, STAM will lead the rapid growth in materials science, inspiring research into new materials for the future and leading the next generation of materials science and technology. It is my honor to work with members of

  2. New direct compression excipient from tigernut starch: physicochemical and functional properties.

    Science.gov (United States)

    Builders, Philip F; Anwunobi, Patricia A; Mbah, Chukwuemeka C; Adikwu, Michael U

    2013-06-01

    Tigernut starch has been isolated and modified by forced retrogradation of the acidic gel by freezing and thawing processes. Relevant physicochemical and functional properties of the new excipient (tigernut starch modified by acid gelation and accelerated (forced) retrogradation (ST(AM))) were evaluated as a direct compression excipient in relation to the native tigernut starch (ST(NA)), intermediate product (tigernut starch modified by acid gelation (ST(A))), and microcrystalline cellulose (MCC). The particle morphology, swelling capacity, moisture sorption, differential scanning calorimeter (DSC) thermographs and X-ray powder diffraction (XRD) patterns, flow, dilution capacity, and tablet disintegration efficiency were evaluated. The particles of ST(NA) were either round or oval in shape, ST(A) were smooth with thick round edges and hollowed center while ST(AM) were long, smooth, and irregularly shaped typically resembling MCC. The DSC thermographs of ST(NA) and MCC showed two endothermic transitions as compared with ST(A) and ST(AM) which showed an endothermic and an exothermic. The moisture uptake, swelling, flow, and dilution capacity of ST(AM) were higher than those of MCC, ST(A), and ST(NA). The XRD pattern and moisture sorption profile of ST(AM) showed similarities and differences with ST(NA), ST(A), and MCC that relate the modification. Acetylsalicylic acid (ASA) tablets containing ST(AM) disintegrated at 3±0.5 min as compared with the tablets containing ST(NA), ST(A), and MCC which disintegrated at 8.5±0.5, 10±0.5, and 58±0.8 min, respectively. The study shows the physicochemical properties of tigernut starch modified by forced retrogradation as well as its potential as an efficient direct compression excipient with enhanced flow and disintegration abilities for tablets production.

  3. Use of transformed data sets in examination of relationship between growth of trees and weather parameters

    Directory of Open Access Journals (Sweden)

    Márton Edelényi

    2011-11-01

    Full Text Available Analysing and stability improving methods were studied for the examination of relationships between tree growth and meteorological factors according to our requirements. In order to explore more complex relations from primary data sets secondary data series had to be systematically transformed and a uniform analysis process was developed for their investigation. The structure of the Systematic Transformation Analysing Method (STAM has three main components. The first module derives input data from the original series without any essential changes. The transformation unit produces secondary data series using a moving window technique. The thirds component performs the examinations. STAM also allows the application in several other research fields.

  4. Experiment list: SRX069125 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available phageal epithelial cells 43784768,95.8,40.9,109725 GSM736532: Stam HEEpiC 2 source_...SRX069125 hg19 DNase-seq DNase-Seq Digestive tract HEEpiC Tissue=epithelium|Lineage=endoderm|Description=eso

  5. Experiment list: SRX069178 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available phageal epithelial cells 52668033,95.9,42.1,136405 GSM736585: Stam HEEpiC 1 source_...SRX069178 hg19 DNase-seq DNase-Seq Digestive tract HEEpiC Tissue=epithelium|Lineage=endoderm|Description=eso

  6. Experiment list: SRX080375 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available phageal epithelial cells 28024999,96.6,13.1,41872 GSM749712: Stam HEEpiC CTCF 1 sou...SRX080375 hg19 TFs and others CTCF Digestive tract HEEpiC Tissue=epithelium|Lineage=endoderm|Description=eso

  7. Experiment list: SRX080389 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available phageal epithelial cells 13830153,91.1,10.0,32467 GSM749726: Stam HEEpiC CTCF 2 sou...SRX080389 hg19 TFs and others CTCF Digestive tract HEEpiC Tissue=epithelium|Lineage=endoderm|Description=eso

  8. Karakterisering van de zuurgevoeligheid van Salmonella typhimurium faagtype DT104

    NARCIS (Netherlands)

    de Jonge R; van Leusden FM; Dufrenne JB; Ritmeester WS; Delfgou-van Asch EHM; van Pelt W; LBG

    1999-01-01

    Het aantal gevallen van salmonellosis in Nederland veroorzaakt door Salmonella typhimurium faagtype DT104 is toegenomen van 10 in 1985 tot 163 in 1997 (10% van alle gevallen van salmonellosis). De stam lijkt zijn oorsprong te hebben in het Verenigd Koninkrijk. Daar wordt inmiddels 20% van alle gev

  9. Assessment of Benefits and Drawbacks of Using Fuzzy Logic, Especially in Fire Control Systems

    Science.gov (United States)

    1994-03-01

    Netherlands, June 1991 [2] ’Technologieverkenning Vage Logica ’ (Dutch), Stam Tijdschriften, The Netherlands, April 1992 [3] ’Fuzzy Logic; vage logica voor...1991 [14] ’An autopilot for ships designed with fuzzy sets’,Proceedings of 5th IFAC/IFIP Int. Conf. on Digital Computer Applications to Process

  10. Growth of the endocrine pancreas

    DEFF Research Database (Denmark)

    Gaarn, Louise Winkel

    regulering. Der er blevet foreslaaet flere forskellige strategier til at generere klinisk anvendelige ß-celler. Disse omfatter differentiering af embryonale stamceller, deling af eksisterende voksne ß-celler, differentiering af voksne stam-/progenitorceller celler samt omprogrammering af ikke-ß-celler til ß...

  11. The psychologist's dilemma ESHHS Paper Utrecht 2010

    NARCIS (Netherlands)

    van Hezewijk, René; Stam, Henderikus

    2010-01-01

    The Psychologists Dilemma Game René van Hezewijk and Henderikus Stam Among the recurrent cleavages that define 20th century psychology is the deep division between psychologies that distance the psychologist from the phenomenon under investigation from those that engage the question under investi

  12. Majad moodsalt tänavalt / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    1927. a. Stuttgarti ehitatud Weissenhofi elamugrupist (Le Corbusier, P. Jeanneret, J. J. P. Oud, M. Stam, W. Gropius, P. Behrens, M. ja B. Taut jt.) ja 1933. a. valminud Vaarika-Maasika t. asumist (A. Volberg, E. J. Kuusik, E. Jacoby, E. Lohk, F. de Vries). Näitus "Moodsad näidisasumid: Weissenhof & Maasika-Vaarika" Rotermanni soolalaos.

  13. Bacteriologisch en serologisch onderzoek van Helicobacter species bij laboratoriummuizen

    NARCIS (Netherlands)

    Root R; Admiraal J; Koedam MA; Thuis HCW; Veenema JL; LIS; LPI

    1998-01-01

    Helicobacter soorten zijn spiraalvormige Gramnegatieve bacterien die voorkomen in het maagdarmkanaal van mens en dier. Helicobacter hepaticus koloniseert bij muizen o.a. het ileum en het cecum en is bij meerdere muizenstammen geassocieerd met chronische actieve hepatitis en bij de A/J stam met

  14. Changes in Thinking for Speaking: A Longitudinal Case Study

    Science.gov (United States)

    Stam, Gale

    2015-01-01

    Cross-linguistic research on motion events has shown that Spanish speakers and English speakers have different patterns of thinking for speaking about motion, both linguistically and gesturally (for a review, see Stam, 2010b). Spanish speakers express path linguistically with verbs, and their path gestures tend to occur with path verbs, whereas…

  15. Oriënterend onderzoek over de reuzen- en dwergplanten in F1 en volgende generaties van Phaseolus vulgaris L. x Phaseolus multiflorus Lam.

    NARCIS (Netherlands)

    Geerts, Sipke Johannes

    1949-01-01

    A cross is studied between the selffertilising bush bean (Phaseolus vulgaris L.) "Zeeuwse Bruine Boon" and crossfertilising runner bean (Phaseolus multiflorus Lam.) "stam" (a scarlet flowering stockrunner-bean) or some other (climbing) runners. With the bushbean as mother this cross easily results i

  16. Planten inenten hulpmiddel bij gebrek aan resistentie : Cross protection bruikbaar alternatief als resistentie ontbreekt

    NARCIS (Netherlands)

    Kierkels, T.; Vlak, J.M.; Heuvelink, E.

    2009-01-01

    Enten met een zwakke virusstam om de plant te beschermen tegen een agressieve variant is met veel ‘mitsen’ en ‘maren’ omgeven. In principe is cross protection, zoals dit heet, mogelijk. De plant vertoont zelf een afweerreactie en de eiwitten van de zwakke stam belemmeren vermenigvuldiging van de agr

  17. Majad moodsalt tänavalt / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    1927. a. Stuttgarti ehitatud Weissenhofi elamugrupist (Le Corbusier, P. Jeanneret, J. J. P. Oud, M. Stam, W. Gropius, P. Behrens, M. ja B. Taut jt.) ja 1933. a. valminud Vaarika-Maasika t. asumist (A. Volberg, E. J. Kuusik, E. Jacoby, E. Lohk, F. de Vries). Näitus "Moodsad näidisasumid: Weissenhof & Maasika-Vaarika" Rotermanni soolalaos.

  18. The psychologist's dilemma ESHHS Paper Utrecht 2010

    NARCIS (Netherlands)

    van Hezewijk, René; Stam, Henderikus

    2010-01-01

    The Psychologists Dilemma Game René van Hezewijk and Henderikus Stam Among the recurrent cleavages that define 20th century psychology is the deep division between psychologies that distance the psychologist from the phenomenon under investigation from those that engage the question under investi

  19. The psychologist's dilemma ESHHS Paper Utrecht 2010

    NARCIS (Netherlands)

    van Hezewijk, René; Stam, Henderikus

    2010-01-01

    The Psychologists Dilemma Game René van Hezewijk and Henderikus Stam Among the recurrent cleavages that define 20th century psychology is the deep division between psychologies that distance the psychologist from the phenomenon under investigation from those that engage the question under

  20. Kenia en de ‘stammenstrijd’

    NARCIS (Netherlands)

    Dietz, T.; Rutten, M.

    2008-01-01

    In de media worden de gewelddadigheden na de verkiezingen in Kenia afgeschilderd als een etnische strijd tussen de grootste stam, de Kikuyu van 'winnaar' Kibaki, en een 'kleine minderheidsgroep', de Luo, van oppositieleider Odinga. De situatie in multietnisch Kenia ligt echter veel ingewikkelder -

  1. Experiment list: SRX143822 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 54 GSM918730: LICR ChipSeq WholeBrain CTCF E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; ... datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organism...=mouse || cell description=Whole Brain || cell sex=U || antibody=CTCF || antibody antibodydescription=rabbit

  2. Oriënterend onderzoek over de reuzen- en dwergplanten in F1 en volgende generaties van Phaseolus vulgaris L. x Phaseolus multiflorus Lam.

    NARCIS (Netherlands)

    Geerts, Sipke Johannes

    1949-01-01

    A cross is studied between the selffertilising bush bean (Phaseolus vulgaris L.) "Zeeuwse Bruine Boon" and crossfertilising runner bean (Phaseolus multiflorus Lam.) "stam" (a scarlet flowering stockrunner-bean) or some other (climbing) runners. With the bushbean as mother this cross easily results i

  3. Mossen en kortsmossen op dood beukenhout

    NARCIS (Netherlands)

    Dort, van K.W.; Hees, van A.F.M.

    2003-01-01

    Tweede artikel in een serie van drie over de rol van dood beukenhout voor de biodiversiteit. In Nederlandse beukenbossen op zowel zand- als kleigrond zijn dode beukenstammen geïnventariseerd op het voorkomen van mossen (bladmossen; levermossen) en korstmossen. De soortenrijkdom per stam is sterk afh

  4. Experiment list: SRX069230 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Carcinoma Hepatocellular 50956337,52.3,46.2,40764 GSM736637: Stam HepG2 1 source_name=HepG2 || biomateria...l_provider=ATCC || cell=HepG2 || cell organism=Human || cell description=liver carcinoma || cell karyotype=c

  5. Experiment list: SRX037108 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Carcinoma Hepatocellular 248320583,89.7,54.5,73094 GSM646559: Stam HepG2 source_name=HepG2 || biomaterial..._provider=ATCC || cell=HepG2 || cell organism=Human || cell description=liver carcinoma || cell karyotype=ca

  6. Effects of pesticides, polychlorinated biphenyls and metals on the growth and reproduction of Acanthamoeba castellanii

    Energy Technology Data Exchange (ETDEWEB)

    Prescott, L.M.; Kubovec, M.K.; Tryggestad, D.

    1977-07-01

    The effects of pollutants (pesticides, PCB and metals) were studied in the free-living amoeba, Acanthamoeba castellanii. Eight pesticides were used--the insecticides dieldrin, aldrin and sevin, and the herbicides linuron, stam F-34, IPC, atrazine and simazine. It was shown that the sensitivity of A. castellanii to pesticides varied greatly. The population growth was inhibited by linuron, stam F-34, IPC, sevin and atrazine at a level of 10 mg/l. The polychlorinated biphenyl, Arochor 1254, had no significant effect at a concentration of 0.01 mg/l (10 ppb). The studies with metal ions showed that A. castellanii was unaffected by moderately high levels of Cu and Zn, but was sensitive to the presence of Pb and mercuric ions.

  7. Effect of Interstitials on the Trapping of Hydrogen in Iron-Single Crystals

    Science.gov (United States)

    1992-01-01

    UNCLASSIFIED uL Stam’ac ;orm .38 Rev 2-89 4 FINAL REPORT ON HYDROGEN PERMEATION AND POSITRON ANNIHILATION STUDY OF ALPHA - IRON SINGLE CRYSTALS P J A M E...AND BOTH WERE SMALLER THAN 178 KJOULES FOR VACANCY MIGRATION -SELF-DIFFUSION - IN ALPHA - IRON , 5. DISLOCATION PROFILE FORMED BY MECHANICAL POLISHING...1984. Hydrogen Permeation and Positron Annilhilation Study of Alpha Iron Crystals," James T. Waber. Workshop on Surface Science and Technology at the

  8. Experiment list: SRX080383 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX080383 hg19 Input control Input control Neural HA-sp Tissue=spinal cord|Lineage=...ectoderm|Description=astrocytes spinal cord 32808569,97.3,3.2,1174 GSM749720: Stam HA-sp Input 1 source_name...=HA-sp || biomaterial_provider=ScienCell || cell=HA-sp || cell organism=Human || cell description=Human astrocytes spinal

  9. Experiment list: SRX069130 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX069130 hg19 DNase-seq DNase-Seq Neural HA-sp Tissue=spinal cord|Lineage=ectoderm...aterial_provider=ScienCell || cell=HA-sp || cell organism=human || cell description=Human astrocytes spinal ...|Description=astrocytes spinal cord 5262220,98.4,23.1,9555 GSM736537: Stam HA-sp 1 source_name=HA-sp || biom

  10. Politics and Policy in the Crucible of Interstate Coercion

    Science.gov (United States)

    2011-02-16

    Reiter, Dan and Allan C. Stam, III, Democracies at War. Princeton: Princeton University Press, 2002. Samuelson , Paul A. "The Pure Theory of Public...who can be readily replaced. 6 Ibid., 29-31. For the seminal work on public and private goods more generally, see Paul A. Samuelson , "The Pure... Paul K. Extended Deterrence and the Prevention of War. New Haven: Yale University Press, 1988. Jervis, Robert. Perception and Misperception in

  11. Murine Model of Repeated Exposures to Conspecific Trained Aggressors Simulates Features of Post-Traumatic Stress Disorder

    Science.gov (United States)

    2012-07-20

    Rasmusson and Charney [95], Stam et al. [96], and Siegmund and Wotjak [6]. In our studies, the persis- tence of some acutely altered behaviors after...served in Iraq and Afghanistan: possible explanations. Journal of Traumatic Stress 2010;23:59–68. [6] Siegmund A, Wotjak CT. Toward an animal model...Posttraumatic Stress Disorder (PTSD). Behavioural Brain Research 2009;205:544–9. ral BrR. Hammamieh et al. / Behaviou [11] Siegmund A, Dahlhoff M, Habersetzer

  12. The psychologist's dilemma ESHHS Paper Utrecht 2010

    OpenAIRE

    van Hezewijk, René; Stam, Henderikus

    2010-01-01

    The Psychologists Dilemma Game René van Hezewijk and Henderikus Stam Among the recurrent cleavages that define 20th century psychology is the deep division between psychologies that distance the psychologist from the phenomenon under investigation from those that engage the question under investigation from the perspective of the reflexive capacities of the psychologist as one among other human beings and/or members of a specific culture. Most obvious was the emergence – in the late nineteent...

  13. Experiment list: SRX188660 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is the depletion of this subset of T-lymphocytes. 274076701,92.5,57.0,63750 GSM1003833: UW DnaseDgf THelper...-Activated adult-8wks source_name=THelper-Activated || biomaterial_provider=Stam lab || lab=UW-m || lab desc...tatype description=DNase Digital Footprinting || cell=THelper-Activated || cell organism=mouse || cell descr

  14. Experiment list: SRX188650 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available CEREBELLUM; and other structures in the BRAIN STEM. 264080347,93.2,47.9,243361 GSM1003823: UW DnaseDgf Whole...Brain adult-8wks source_name=WholeBrain || biomaterial_provider=1)Stam lab; 2)CSHL lab || lab=UW-m || lab de...datatype description=DNase Digital Footprinting || cell=WholeBrain || cell organism=mouse || cell description=Who

  15. Experiment list: SRX188655 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1649 GSM1003828: UW DnaseDgf WholeBrain E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; 2)C...| datatype description=DNase Digital Footprinting || cell=WholeBrain || cell orga...nism=mouse || cell description=Whole Brain || cell sex=M || age=E14.5 || age description=Embryonic day 14.5

  16. Palavras, sons e imagens em cartaz: aspectos de intermidialidade no romance Benjamin, de Chico Buarque, e na adaptação cinematográfica de Monique Gardenberg

    Directory of Open Access Journals (Sweden)

    Leila Cristina Barros

    2006-12-01

    presentes e relacionadas intimamente entre si, dentro do filme. A combinação e a fusão dessas relações intertextuais e intermidiáticos, no romance e na adaptação, remetem-nos ao conceito de transtextualidade – desenvolvido por Gérard Genette a partir dos termos “dialogismo”, de Mikhail Bakhtin, e “intertextualidade”, de Julia Kristeva, e apropriado pelo crítico de cinema Robert Stam.

  17. The metafiction in Guel Arraes’ work: an analysis of the film

    Directory of Open Access Journals (Sweden)

    Afonso Barbosa

    2014-07-01

    Full Text Available This article discusses the film Romance, by Guel Arraes, investigating its metafictional particularities. We are interested in examining the aesthetic peculiarities from the director along with his other works, such as Lisbela e o prisioneiro . To do so, we will support in the studies of Robert Stam (2000; 2006; Alexandre Figueirôa and Yvana Fechine (2008; and Gustavo Bernardo (2010.

  18. Active pulmonary tuberculosis: Role for amikacin in early treatment.

    Science.gov (United States)

    Méchaï, F; Figoni, J; Leblanc, C; Gousseff, M; Vignier, N; Bouchaud, O

    2016-09-01

    To evaluate the efficacy of amikacin on sputum conversion during initial sputum smear positive tuberculosis treatment. Single-center observational cohort study (2012-2013) evaluating time to sputum smear conversion with standard treatment (ST) versus standard treatment+amikacin (IV 15mg/kg/day) for seven days (STamK). Forty-five patients were included. Median time to smear negative samples was 26.5 days (14-56) for the 30 (66.7%) patients included in the ST group and 48 days (19.5-69.5) for the 15 patients (33.3%) included in the STamK group (P=0.76). Time to negative culture was only known for 27 patients (61.4%): 47.5 days (26-58) for 18 patients in the ST group and 40 days (14-77) for nine patients in the STamK group. Despite our small sample size, the addition of amikacin in active tuberculosis treatment did not seem to impact time to smear conversion or period of contagiousness. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  19. VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Xuefeng; Hurley, James H. (NIH)

    2010-03-30

    VHS (Vps27, Hrs, and STAM) domains occur in ESCRT-0 subunits Hrs and STAM, GGA adapters, and other trafficking proteins. The structure of the STAM VHS domain-ubiquitin complex was solved at 2.6 {angstrom} resolution, revealing that determinants for ubiquitin recognition are conserved in nearly all VHS domains. VHS domains from all classes of VHS-domain containing proteins in yeast and humans, including both subunits of ESCRT-0, bound ubiquitin in vitro. ESCRTs have been implicated in the sorting of Lys63-linked polyubiquitinated cargo. Intact human ESCRT-0 binds Lys63-linked tetraubiquitin 50-fold more tightly than monoubiquitin, though only 2-fold more tightly than Lys48-linked tetraubiquitin. The gain in affinity is attributed to the cooperation of flexibly connected VHS and UIM motifs of ESCRT-0 in avid binding to the polyubiquitin chain. Mutational analysis of all the five ubiquitin-binding sites in yeast ESCRT-0 shows that cooperation between them is required for the sorting of the Lys63-linked polyubiquitinated cargo Cps1 to the vacuole.

  20. Transtextualidade e dialogismo em Admirável Mundo Novo e Matrix

    OpenAIRE

    Mylene Fonseca Garcia

    2007-01-01

    A adaptação fílmica tem encontrado na literatura sua parceria mais bem sucedida.Seu estudo, no entanto, durante décadas, se restringiu à análise essencialista acerca das especialidades de cada meio. Atualmente, a obra de Robert Stam, discutindo a teoria de transtextualidade delineada por Gérard Genette, oferece uma proposta diferente, ao abordar as pontecialidades dialógicas e discursivas presentes na adaptação fílmica. Nesse sentido, as principais transformações transtextuais do corpus forma...

  1. Arquetipos de Arquitectura Moderna en la Revista Arquitectura: Su difusión y práctica en España (1925-1936).

    OpenAIRE

    San Antonio Gomez, Jose Carlos de

    2012-01-01

    Es conocido el papel que desempeñó la revista Arquitectura en la difusión en España de las diferentes manifestaciones de la arquitectura moderna. Sus páginas recogen obras de los más conocidos arquitectos: Breuer, Brinkman, Van der Vlugt, De Klerk, Dudok, Gropius, Le Corbusier, Mendelsohn, Meyer, Mies van der Rohe, Oud, Poelzig, Rietveld, Scharoun, Stam, Taut, Tessenow, Van Doesburg, Van Eesteren? Algunas de estas obras hoy son cánones reconocidos por la historiografía, pero casi desconocidas...

  2. A Comunicação no Cinema dos Sentidos: Abordando a Imersão sob a Perspectiva do Som

    OpenAIRE

    OPOLSKI, Débora Regina

    2015-01-01

    O presente trabalho pretende abordar a imersão criada pelo Cinema dos Sentidos sob a perspectiva do som. De acordo com Robert Stam (2011), no Cinema dos Sentidos, a sensação predomina sobre a narrativa e o som cinematográfico aparece como um elemento capaz de aumentar a sensação de realidade da imagem. A criação da imersão é discutida com base em três aspectos sonoros: o estabelecimento do ponto de escuta; o som no supercampo em conjunto com as questões da espacialidade sonora e; o hiper-real...

  3. Arquetipos de Arquitectura Moderna en la Revista Arquitectura: Su difusión y práctica en España (1925-1936).

    OpenAIRE

    San Antonio Gomez, Jose Carlos de

    2012-01-01

    Es conocido el papel que desempeñó la revista Arquitectura en la difusión en España de las diferentes manifestaciones de la arquitectura moderna. Sus páginas recogen obras de los más conocidos arquitectos: Breuer, Brinkman, Van der Vlugt, De Klerk, Dudok, Gropius, Le Corbusier, Mendelsohn, Meyer, Mies van der Rohe, Oud, Poelzig, Rietveld, Scharoun, Stam, Taut, Tessenow, Van Doesburg, Van Eesteren? Algunas de estas obras hoy son cánones reconocidos por la historiografía, pero casi desconocidas...

  4. Experiment list: SRX185817 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SM1000096: LICR ChipSeq WholeBrain H3K4me1 E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; ... datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organism...=mouse || cell description=Whole Brain || cell sex=U || antibody=H3K4me1 || antibody antibodydescription=rab...SRX185817 mm9 Histone H3K4me1 Embryo Embryonic brains NA 84760373,66.7,29.3,61623 G

  5. Experiment list: SRX185827 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX185827 mm9 Histone H3K9me3 Embryo Embryonic brains NA 73862125,87.3,33.7,1308 GS...M1000106: LICR ChipSeq WholeBrain H3K9me3 E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; 2...datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organism=...mouse || cell description=Whole Brain || cell sex=M || antibody=H3K9me3 || antibody antibodydescription=rabb

  6. Experiment list: SRX185816 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SM1000095: LICR ChipSeq WholeBrain H3K4me3 E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; ... datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organism...=mouse || cell description=Whole Brain || cell sex=U || antibody=H3K4me3 || antibody antibodydescription=rab...SRX185816 mm9 Histone H3K4me3 Embryo Embryonic brains NA 57217194,76.8,43.8,34752 G

  7. Experiment list: SRX185793 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SM1000072: LICR ChipSeq WholeBrain H3K36me3 E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab;...| datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organis...m=mouse || cell description=Whole Brain || cell sex=M || antibody=H3K36me3 || antibody antibodydescription=r...SRX185793 mm9 Histone H3K36me3 Embryo Embryonic brains NA 75345581,86.1,16.8,1199 G

  8. Experiment list: SRX185815 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX185815 mm9 Histone H3K27ac Embryo Embryonic brains NA 23713773,96.1,9.1,32352 GS...M1000094: LICR ChipSeq WholeBrain H3K27ac E14.5 source_name=WholeBrain || biomaterial_provider=1)Stam lab; 2...datatype description=Chromatin IP Sequencing || cell=WholeBrain || cell organism=...mouse || cell description=Whole Brain || cell sex=U || antibody=H3K27ac || antibody antibodydescription=rabb

  9. Proteome Characteristics of Non-Alcoholic Steatohepatitis Liver Tissue and Associated Hepatocellular Carcinomas

    Science.gov (United States)

    Kakehashi, Anna; Stefanov, Vasily E.; Ishii, Naomi; Okuno, Takahiro; Fujii, Hideki; Kawai, Kazuaki; Kawada, Norifumi; Wanibuchi, Hideki

    2017-01-01

    To uncover mechanisms of nonalcoholic steatohepatitis (NASH) associated hepatocarcinogenesis, we compared the proteomes of human NASH-associated liver biopsies, resected hepatocellular carcinomas (HCCs) and HCCs of HCV+ patients with normal liver tissue of patients with gastrointestinal tumor metastasis, in formalin-fixed paraffin-embedded samples obtained after surgery in our hospital during the period from 2006 to 2011. In addition, proteome analysis of liver tumors in male STAM NASH-model mice was performed. Similar changes in the proteome spectrum such as overexpression of enzymes involved in lipid, cholesterol and bile acid biosynthesis and examples associated with suppression of fatty acid oxidation and catabolism, alcohol metabolism, mitochondrial function as well as low expression levels of cytokeratins 8 and 18 were observed in both human NASH biopsies and NASH HCCs, but not HCV+ HCCs. Alterations in downstream protein expression pointed to significant activation of transforming growth factor β, SMAD family member 3, β-catenin, Nrf2, SREBP-LXRα and nuclear receptor-interacting protein 1 (NRIP1), and inhibition of PPARs and p53 in human NASH biopsies and/or HCCs, suggesting their involvement in accumulation of lipids, development of fibrosis, oxidative stress, cell proliferation and suppression of apoptosis in NASH hepatocarcinogenesis. In STAM mice, PPARs inhibition was not obvious, while expression of cytokeratins 8 and 18 was elevated, indicative of essential differences between human and mouse NASH pathogenesis. PMID:28218651

  10. "I am in control of my life": the male homosexual stereotype in the movies A Navalha na carne (1969 and a Rainha Diaba (1974 "Na minha vida, mando eu": o estereótipo do homossexual masculino nos filmes A navalha na carne (1969 e A Rainha Diaba (1974

    Directory of Open Access Journals (Sweden)

    Rafael de Luna Freire

    2009-09-01

    Full Text Available "I am in control of my life": the male homosexual stereotype in the movies A Navalha na Carne (1969 and A Rainha Diaba (1974 — This paper discusses the question of male homosexual stereotyping in Brazilian cinema, taking as the object of study the homosexual characters of the movies A navalha na carne (directed by Braz Chediak, 1970 and A Rainha Diaba (directed by Antonio Carlos da Fontoura, 1974, based on the works of the author Plínio Marcos. Using texts by authors such as Richard Dyer, Robert Stam and Ella Shohat, I defend the need and importance of a historiographical analysis of stereotypes in cinema. O presente artigo discute a questão do estereótipo do homossexual masculino no cinema brasileiro, tomando como objeto de estudo os personagens homossexuais dos filmes A navalha na carne (1970 e A Rainha Diaba (1974, baseados em obras do autor santista Plínio Marcos. Através de textos de autores como Richard Dyer, Robert Stam e Ella Shohat, defendo a necessidade e a importância de uma análise historicizante dos estereótipos no cinema.

  11. NAS TEIAS DA INTERMIDIALIDADE: O CARANDIRU DE VARELLA E O DE BABENCO

    Directory of Open Access Journals (Sweden)

    Norma de Siqueira Freitas

    2009-12-01

    Full Text Available RESUMO: Reflexão sobre o processo de adaptação de obras da literatura, transmutadas para a linguagem cinematográfica. O objetivo é a análise do trânsito entre os textos: Estação Carandiru (EC, livro de Drauzio Varella e o filme Carandiru, de Hector Babenco. Analisaremos o deslocamento do signo verbal ao visual a partir dos pressupostos de Andrew, Bazin, Gardies, Genette e Stam. Em diálogo com as principais teorias do cinema, adaptação concebida, então, como recriação, porquanto mudança de veículos artísticos exigirá processo de transformação pertinente. PALAVRAS-CHAVE: literatura, cinema, adaptação, linguagem. ABSTRACT:Thisarticleisareflectionontheprocessoftheadaptation of literary works by their transmutation into cinematic language. It intends to analyze the transit between two texts: Drauzio Varella’s book Estação Carandiru (EC and Hector Babenco’s film Carandiru. The displacement from the verbal to the visual sign will be analyzed by way of the theories of Andrew, Bazin, Gardies, Genette and Stam. Following the main theories on cinema, adaptation is conceived as re-creation, since a change in artistic vehicles requires a pertinent transformation process. KEYWORDS: literature, cinema, adaptation, language.

  12. The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.

    Science.gov (United States)

    Row, Paula E; Liu, Han; Hayes, Sebastian; Welchman, Rebecca; Charalabous, Panagoula; Hofmann, Kay; Clague, Michael J; Sanderson, Christopher M; Urbé, Sylvie

    2007-10-19

    We have identified and characterized a Microtubule Interacting and Transport (MIT) domain at the N terminus of the deubiquitinating enzyme UBPY/USP8. In common with other MIT-containing proteins such as AMSH and VPS4, UBPY can interact with CHMP proteins, which are known to regulate endosomal sorting of ubiquitinated receptors. Comparison of binding preferences for the 11 members of the human CHMP family between the UBPY MIT domain and another ubiquitin isopeptidase, AMSH, reveals common interactions with CHMP1A and CHMP1B but a distinct selectivity of AMSH for CHMP3/VPS24, a core subunit of the ESCRT-III complex, and UBPY for CHMP7. We also show that in common with AMSH, UBPY deubiquitinating enzyme activity can be stimulated by STAM but is unresponsive to its cognate CHMPs. The UBPY MIT domain is dispensable for its catalytic activity but is essential for its localization to endosomes. This is functionally significant as an MIT-deleted UBPY mutant is unable to rescue its binding partner STAM from proteasomal degradation or reverse a block to epidermal growth factor receptor degradation imposed by small interfering RNA-mediated depletion of UBPY.

  13. Pymiedap: a versatile radiative transfer code with polarization for terrestrial (exo)planets.

    Science.gov (United States)

    Rossi, Loïc; Stam, Daphne; Hogenboom, Michael

    2016-04-01

    Polarimetry promises to be an important method to detect exoplanets: the light of a star is usually unpolarized te{kemp1987} while scattering by gas and clouds in an atmosphere can generate high levels of polarization. Furthermore, the polarization of scattered light contains information about the properties of the atmosphere and surface of a planet, allowing a possible characterization te{stam2008}, a method already validated in the solar system with Venus te{hansen1974,rossi2015}. We present here Pymiedap (Python Mie Doubling-Adding Program): a set of Python objects interfaced with Fortran radiative transfer codes that allows to define a planetary atmosphere and compute the flux and polarization of the light that is scattered. Several different properties of the planet can be set interactively by the user through the Python interface such as gravity, distance to the star, surface properties, atmospheric layers, gaseous and aerosol composition. The radiative transfer calculations are then computed following the doubling-adding method te{deHaan1987}. We present some results of the code and show its possible use for different planetary atmospheres for both resolved and disk-integrated measurements. We investigate the effect of gas, clouds and aerosols composition and surface properties for horizontally homogeneous and inhomogenous planets, in the case of Earth-like planets. We also study the effect of gaseous absorption on the flux and polarization as a marker for gaseous abundance and cloud top altitude. [1]{kemp1987} Kemp et al. The optical polarization of the sun measured at a sensitivity of parts in ten million. Nature, 1987, 326, 270-273 [2]{stam2008} Stam, D. M. Spectropolarimetric signatures of Earth-like extrasolar planets. A&A, 2008, 482, 989-1007 [3]{hansen1974} Hansen, J. E. & Hovenier, J. W. Interpretation of the polarization of Venus. Journal of Atmospheric Sciences, 1974, 31, 1137-1160 [4]{rossi2015} Rossi et al. Preliminary study of Venus cloud layers

  14. An exploratory study of the impact of an inquiry-based professional development course on the beliefs and instructional practices of urban inservice teachers

    Science.gov (United States)

    Suters, Leslie Ann

    Five urban teachers completed a total of 50 contact hours of professional development in which they: participated in authentic, inquiry-based experiences facilitated by a scientist; learned new science content related to the nature of science and scientific inquiry; developed inquiry-based lesson plans to implement in their classrooms; and developed science-specific strategies to mentor novice and experienced teachers. The focus of this research was to determine changes in their: beliefs and instructional practices; understanding of scientific literacy; and efficacy toward mentoring other teachers. A collective case study methodology was used in which participants completed questionnaires and were observed and interviewed, prior to and at the completion of the course. They were also asked to complete reflective journal questions during the course. While the teachers' beliefs did not change as measured by the Teacher's Pedagogical Philosophy Interview (TPPI) (teacher-centered beliefs for "Teacher Actions" and "Teacher and Content"; conceptual/student-centered for "Student Actions" and "Philosophy of Teaching"), their teacher-centered behaviors changed to conceptual/student-centered as measured by the Secondary Science Teachers Analysis Matrix (STAM). Their responses to the Constructivist Learning Environment Survey (CLES) generally correlated with their post-STAM results. Participants gained a better understanding of the creative aspect of the nature of science as measured by the Modified Nature of Scientific Knowledge Scale (MNSKS) instrument, while two novice teachers improved their personal science teaching efficacy after participation in the course as measured by the Science Teaching Efficacy Belief Instrument (STEBI). Four of the five teachers felt better prepared to mentor others to use inquiry-based instruction. In contrast to these positive trends, their outcome expectancy beliefs (STEBI subscale) were generally lower than their perceived personal teaching

  15. Distribution of Wave Loads for Design of Crown Walls in Deep and Shallow Water

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Quvang Harck; Andersen, Thomas Lykke

    2014-01-01

    This paper puts forward a new method to determine horizontal wave loads on rubble mound breakwater crown walls with specific exceedance probabilities based on the formulae by Nørgaard et al. (2013) as well as presents a new modified version of the wave run-up formula by Van der Meer & Stam (1992......). Predictions from the method are compared to measured horizontal wave loads from scaled model tests, and the new method provides results which are in agreement with measured values as long as the wave loads on the crown wall are relatively impulsive. Another aim of the paper has been to compare...... the displacements of a crown wall exposed to wave loads with different exceedance probabilities in an overload situation (in this case the loads exceeded by 0.1 % and 1/250 of the incident waves). The comparison is made using the assumption that the Eigenfrequency of the crown wall and breakwater is significantly...

  16. Detecting dark matter waves with precision measurement tools

    CERN Document Server

    Derevianko, Andrei

    2016-01-01

    Virialized Ultra-Light Fields (VULFs) while being viable cold dark matter candidates can also solve the standard model hierarchy problem. Direct searches for VULFs due to their non-particle nature require low-energy precision measurement tools. Here we consider scalar VULF candidates. While the previous proposals have focused on detecting coherent oscillations of the measured signals at the VULF Compton frequencies at the device location, here we point out that VULFs also have a distinct spatial signature, forming dark matter waves. Thereby the discovery reach can be improved by using distributed networks of precision measurement tools. We find the expected dark-matter wave signal by deriving spatio-temporal two-point VULF correlation function. Based on the developed formalism for coherence properties of dark-matter fields, we propose several experiments for dark matter wave detection. In the most basic version, the modifications to already running experiments are minor and only require GPS-assisted time-stam...

  17. Um outro olhar: aspectos contrahegemônicos no filme Bem-vindo = Another look: aspects of counterhegemony into the movie Welcome

    Directory of Open Access Journals (Sweden)

    Oliveira, Eliane Maria de

    2013-01-01

    Full Text Available Os atentados terroristas de 11 de setembro de 2001 reinseriram a questão imigratória nos meios de comunicação, juntamente com temáticas relacionadas à (in segurança e ao (desemprego. O estrangeiro, o outro, passou a ser caracterizado como ameaça em um sistema discursivo que mesclava ficção e realidade: tanto em filmes quanto em noticiários, o imigrante passava a ser apresentado como um problema a ser resolvido, em discursos que se reforçavam, constituindo o que pode ser denominado como discurso hegemônico. Neste trabalho, tendo como referencial teórico Gramsci e Robert Stam, buscamos identificar aspectos de um discurso contrahegemônico no filme Bem-vindo

  18. Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

    Directory of Open Access Journals (Sweden)

    Eunice Yuen Ting Lau

    2016-05-01

    Full Text Available Like normal stem cells, tumor-initiating cells (T-ICs are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesized that cancer-associated fibroblasts (CAFs would regulate liver T-ICs. We found that the presence of α-SMA(+ CAFs correlates with poor clinical outcome. CAF-derived HGF regulates liver T-ICs via activation of FRA1 in an Erk1,2-dependent manner. Further functional analysis identifies HEY1 as a direct downstream effector of FRA1. Using the STAM NASH-HCC mouse model, we find that HGF-induced FRA1 activation is associated with the fibrosis-dependent development of HCC. Thus, targeting the CAF-derived, HGF-mediated c-Met/FRA1/HEY1 cascade may be a therapeutic strategy for the treatment of HCC.

  19. Arte e cultura, uma sinonímia imprópria

    Directory of Open Access Journals (Sweden)

    Guilherme Antônio Carneiro de Sant'Ana

    2014-12-01

    Full Text Available O presente artigo nasceu da percepção de uma imprecisão conceitual comum em trabalhos sobre cinema, qual seja, a propagação de uma ambiguidade entre os termos arte e cultura. No entanto, em termos práticos, o significado atribuído a cada um destes termos parece estar associado à existência de matrizes implícitas que orientam entendimentos específicos acerca do objeto comunicativo– as matrizes artística e culturalista. Partindo das interpretações empreendidas por Paul Ricoeur e Robert Stam acerca da noção aristotélica de mímesis, este artigo procura efetuar uma limpeza do terreno conceitual ao precisar os significados que os termos arte e cultura assumem no interior das matrizes artística e culturalista.

  20. Reverse Brunn-Minkowski and reverse entropy power inequalities for convex measures

    CERN Document Server

    Bobkov, Sergey

    2011-01-01

    We develop a reverse entropy power inequality for convex measures, which may be seen as an affine-geometric inverse of the entropy power inequality of Shannon and Stam. The specialization of this inequality to log-concave measures may be seen as a version of Milman's reverse Brunn-Minkowski inequality. The proof relies on a demonstration of new relationships between the entropy of high dimensional random vectors and the volume of convex bodies, and on a study of effective supports of convex measures, both of which are of independent interest, as well as on Milman's deep technology of $M$-ellipsoids and on certain information-theoretic inequalities. As a by-product, we also give a continuous analogue of some Pl\\"unnecke-Ruzsa inequalities from additive combinatorics.

  1. Superman como produto midiático: abordagens históricas e tendências contemporâneas do diálogo intertextual entre cinema e graphic novels na transposição fímica Man of Steel (2013

    Directory of Open Access Journals (Sweden)

    Rita de Cássia Alves Souza

    2014-07-01

    Full Text Available A intensificação no lançamento de produções fílmicas adaptadas de Graphic Novels torna o diálogo intermidiático entre Cinema e História em Quadrinhos bem mais atraente. Este trabalho faz uma análise dos processos criativos de adaptação entre a HQs e o suporte fílmico, refletindo sobre a atualização da personagem do Superman, de modo a estimular a curiosidade pela matéria como produto midiático, objetivando assim, contribuir para um melhor entendimento da relação intermidiática entre Cinema e Histórias em Quadrinhos. Para tanto, utilizam-se os conceitos teóricos de Humberto Eco e Robert Stam, assim como dos pesquisadores Denise Guimarães, Arlindo Machado, Will Eisner, entre outros.

  2. Manual of electromobility 2012; Handbuch Elektromobilitaet 2012

    Energy Technology Data Exchange (ETDEWEB)

    Korthauer, Reiner (ed.)

    2012-07-01

    The third edition of the manual of electromobility reports on the actual state of electromobility and consists of the following brief articles: (1) Electromobility - The French point of view (C. Stam); (2) Elecromobility - Developments at foreign markets (O. Idem); (3) Target group analysis and market development of the electromobility (G.A. Teichmann); (4) Electromobility and electro-hype - Potentials, performance, alternatives (J. Adolf); (5) Resource efficiency of electromobility (M. Buchert); (6) Electrically mobil with hydrogen and fuel cells (B. Scheppart); (7) Electric drive in hybrid and fully electric vehicles (M. Doppelbauer); (8) Future battery technologies from the view of raw material producers (C. Hartnig); (9) Batteries on the test bench - The VDE testlab for batteries and environment (H. Sattler); (10) Smart grids as a necessary infrastructure (A. Hinz); (11) Inductive charging - A procedure of the future (M. Pavlidis); (12) Future chance eco mobility (G. Holtmeier); (13) Standards create safety (K. Hoehne).

  3. A New Way to Lemmatize Adjectives in a User-friendly Zulu–English Dictionary

    Directory of Open Access Journals (Sweden)

    Gilles-Maurice de Schryver

    2011-10-01

    Full Text Available

    Abstract: Traditionally, Zulu adjectives have been lemmatized under their stems only. In this research article, an in-depth analysis is undertaken to make a case for the lemmatization of all frequent adjectival forms with their adjective concords rather. It is shown that the supposed explosion in size of the dictionary may be contained within a corpus-driven Sinclairian framework. The advantages of such a word-like treatment far outnumber the generalizations that have hitherto characterized the lexicographic treatment of adjectives in Zulu. The study is supported by ample dictionary extracts from a Zulu–English dictionary project aimed at junior users. Comparisons with existing dictionaries and textbook data are also made.

    Keywords: LEXICOGRAPHY, LINGUISTICS, GRAMMAR, DICTIONARY, BILINGUAL,CORPUS, LEMMATIZATION, FREQUENCY, ZULU (ISIZULU, ENGLISH, ADJECTIVE,ADJECTIVE STEM, QUALIFICATIVE ADJECTIVE, COPULATIVE ADJECTIVE, USER-FRIENDLY,REAL EXAMPLE, COLLOCATION, COMBINATION, DERIVATION, IDIOMATIC USE,SEMANTIC PROSODY

    Samenvatting: Een nieuwe manier om adjectieven te lemmatiseren in eengebruiksvriendelijk Zoeloe–Engels woordenboek. Traditioneel worden adjectievenin Zoeloe enkel onder hun stam gelemmatiseerd. In dit onderzoeksartikel wordt een grondigeanalyse uitgevoerd met het oog op de invoering van een nieuwe methode waarbij alle frequenteadjectieven met hun adjectiefschakel in het woordenboek worden geplaatst. Er wordt aangetoond datde vooronderstelde explosie in grootte van het woordenboek beperkt kan worden binnen een corpusgedrevenSinclairiaans kader. De voordelen van zo een woordachtige behandeling overstijgenruimschoots de veralgemeningen die totnogtoe de lexicografische behandeling van adjectieven inZoeloe hebben gekarakteriseerd. De studie wordt ondersteund door een groot aantal passages uiteen Zoeloe–Engels woordenboekproject gericht op jonge gebruikers. Vergelijkingen met bestaandewoordenboeken, alsook handboeken

  4. Evolution and Origin of HRS, a Protein Interacting with Merlin, the Neurofibromatosis 2 Gene Product

    Directory of Open Access Journals (Sweden)

    Leonid V. Omelyanchuk

    2009-10-01

    Full Text Available Hepatocyte growth factor receptor tyrosine kinase substrate (HRS is an endosomal protein required for trafficking receptor tyrosine kinases from the early endosome to the lysosome. HRS interacts with Merlin, the Neurofibromatosis 2 (NF2 gene product, and this interaction may be important for Merlin’s tumor suppressor activity. Understanding the evolution, origin, and structure of HRS may provide new insight into Merlin function. We show that HRS homologs are present across a wide range of Metazoa with the yeast Vps27 protein as their most distant ancestor. The phylogenetic tree of the HRS family coincides with species evolution and divergence, suggesting a unique function for HRS. Sequence alignment shows that various protein domains of HRS, including the VHS domain, the FYVE domain, the UIM domain, and the clathrin-binding domain, are conserved from yeast to multicellular organisms. The evolutionary transition from unicellular to multicellular organisms was accompanied by the appearance of a binding site for Merlin, which emerges in the early Metazoa after its separation from flatworms. In addition to the region responsible for growth suppression, the Merlin-binding and STAM-binding domains of HRS are conserved among multicellular organisms. The residue equivalent to tyrosine-377, which is phosphorylated in the human HRS protein, is highly conserved throughout the HRS family. Three additional conserved boxes lacking assigned functions are found in the HRS proteins of Metazoa. While boxes 1 and 3 may constitute the Eps-15- and Snx1-binding sites, respectively, box 2, containing the residue equivalent to tyrosine-377, is likely to be important for HRS phosphorylation. While several functional domains are conserved throughout the HRS family, the STAM-binding, Merlin-binding, and growth suppression domains evolved in the early Metazoa around the time the Merlin protein emerged. As these domains appear during the transition to multicellularity

  5. Vorticity models of ocean surface diffusion in coastal jets and eddies

    Science.gov (United States)

    Cano, D.; Matulka, A.; Sekula, E.

    2010-05-01

    coastal diffusion using image analysis'. Applied Scientific Research, 59,127-142. Carrillo, A.; Sanchez, M.A.; Platonov, A.; Redondo, J.M., (2001). Coastal and Interfacial Mixing. Laboratory Experiments and Satellite Observations. Physics and Chemistry of the Earth, v. B, 26/4. pp. 305-311. Gade, M. and W. Alpers. (1999). Using ERS-2 SAR images for routine observation of marine pollution in European margins. Mediterranean Target Project (MPT)-EUROMARGE-NB Project. Luxemburg, 38, 57. Gade, M., and J. M. Redondo (1999) 'Marine pollution in European coastal waters monitored by the ERS-2 SAR: a comprehensive statistical analysis". IGARSS 99. Hamburg. v. III, 1637-1639., pp. 308-312. Jolly G. W., A. Mangin, F. Cauneau, M. Calatuyud, V. Barale, H. M. Snaith, O.Rud, M. Ishii, M. Gade, J. M. Redondo, A. Platonov (2000). The Clean Seas Project Final Report (ENV4-CT96-0334). Ed. DG XII/D, Brusselas. Martinez Benjamin J.J., L.M. Redondo, J.Jorge & A.Platonov.(1999). Aplication of SAR images in the western Mediterranean Sea. Remote Sensing in 21st Century: Economic and Environmental Applications. Proceedings of the 19th EARSel Symposium on Remote Sensing in the 21st Century. Eds. A.A. Balkema ,Ed. J.L. Casanova. Rotterdam / Brookfiel. pp. 461-465.

  6. Film beyond boundaries: film, migrant narratives and other media Film beyond boundaries: film, migrant narratives and other media

    Directory of Open Access Journals (Sweden)

    Anelise Reich Corseuil

    2008-04-01

    Full Text Available The articles here presented are representative of the debates about the various transformational aspects of film studies, fostering the discussion about the transformations and interactions between national and international narrative forms, the interrelations between film and literature, and film with other media. The critical perspectives here presented range from an emphasis on cultural materialism, dialogism, reception theory, deconstructionism, narrative studies to film aesthetics or film genre, and can be grouped in three major interrelated areas of film studies: adaptation studies, representation and aesthetics, and film and other media. All of them enable a critical perspective as regards the fluidity of the boundaries separating film from other media, such as literature, television, DVDs, and video games, as newer narrative forms that are incorporated by film, and the transformations in terms of aesthetics and forms of representation in contemporary film and media (the transgeneric nature of film, the interrelations between national and international cinemas, and the demands for a broader perception of the overwhelming mediations of the image in our contemporary society. Moreover, the articles are inserted within recent critical debates on adaptation, digital media and national and transnational cinema (Naremore, Sobchack, Druckery and Williams. All articles combine important theoretical concerns with the analysis of specific films. Robert Stam's “Teoria e Prática da Adaptação: da Fidelidade à Intertextualidade” (“Theory and the practice of adaptation: from fidelity to intertextuality” offers a rich perspective on the issue of adaptation in its relationship with critical theory. He analyses the changing critical views on adaptation, which go from the priority given to the canonic literary text, as an origin, to a more fluid, intertextual and dialogical approach to film adaptation. Drawing from Bakhtin's concept of

  7. Film beyond boundaries: film, migrant narratives and other media

    Directory of Open Access Journals (Sweden)

    Anelise Reich Corseuil

    2006-04-01

    Full Text Available The articles here presented are representative of the debates about the various transformational aspects of film studies, fostering the discussion about the transformations and interactions between national and international narrative forms, the interrelations between film and literature, and film with other media. The critical perspectives here presented range from an emphasis on cultural materialism, dialogism, reception theory, deconstructionism, narrative studies to film aesthetics or film genre, and can be grouped in three major interrelated areas of film studies: adaptation studies, representation and aesthetics, and film and other media. All of them enable a critical perspective as regards the fluidity of the boundaries separating film from other media, such as literature, television, DVDs, and video games, as newer narrative forms that are incorporated by film, and the transformations in terms of aesthetics and forms of representation in contemporary film and media (the transgeneric nature of film, the interrelations between national and international cinemas, and the demands for a broader perception of the overwhelming mediations of the image in our contemporary society. Moreover, the articles are inserted within recent critical debates on adaptation, digital media and national and transnational cinema (Naremore, Sobchack, Druckery and Williams. All articles combine important theoretical concerns with the analysis of specific films. Robert Stam's “Teoria e Prática da Adaptação: da Fidelidade à Intertextualidade” (“Theory and the practice of adaptation: from fidelity to intertextuality” offers a rich perspective on the issue of adaptation in its relationship with critical theory. He analyses the changing critical views on adaptation, which go from the priority given to the canonic literary text, as an origin, to a more fluid, intertextual and dialogical approach to film adaptation. Drawing from Bakhtin's concept of dialogism

  8. Revolutionizing Bantu Lexicography — A Zulu Case Study

    Directory of Open Access Journals (Sweden)

    Gilles-Maurice de Schryver

    2011-10-01

    Full Text Available

    ABSTRACT: Zulu uses a conjunctive writing system, that is, a system whereby relatively short linguistic words are joined together to form long orthographic words with complex morphological structures. This has led to the so-called 'stem tradition' in dictionary making — for Zulu, as well as for most other Bantu languages. Given this lemmatization approach has been found to be inadequate for young learners (who fail to isolate stems, the development of a new approach was imperative for them, but until recently deemed impossible to implement. In this paper it is argued that it is now perfectly possible to reverse the unproductive trend, and to opt for the lemmatization of full words for all but one of the word classes in Bantu. This revolution is made possible thanks to the recent availability of relatively large corpora, with which the really frequent citation options may be pinpointed. Rather than a mission statement, this paper offers the result for all word classes. To do so, an actual guide to the use of a Zulu dictionary is re-represented and annotated.

    SAMENVATTING: Bantoe lexicografie radicaal omgooien — een gevalsanalyse voor Zoeloe. Zoeloe maakt gebruik van een conjunctief schrijfsysteem, d.w.z. een systeem waarbij relatief korte linguïstische woorden vast aan elkaar geschreven worden met lange orthografische woorden tot gevolg, die ook nog complexe morfologische structuren vertonen. Dit heeft geleid tot wat men de 'stam traditie' in de lexicografie is gaan noemen — voor Zoeloe, alsook voor de meeste andere Bantoetalen. Aangezien deze lemmatisatieaanpak ongeschikt is gebleken voor jonge gebruikers (die woordstammen maar niet kunnen isoleren, moest voor hen een nieuwe aanpak ontwikkeld worden. Tot voor kort werd zo'n aanpak echter als niet-implementeerbaar beschouwd. In dit artikel wordt geargumenteerd dat het vandaag de dag perfect mogelijk is om de onproductieve trend om te keren, en om te kiezen voor het lemmatiseren

  9. We await for the F¨uhrer’s orders: the Nazi perversion in cinematography

    Directory of Open Access Journals (Sweden)

    Renata Aparecida Frigeri

    2014-12-01

    Full Text Available This work aims to investigate the ideological and intertextual parallels between Triumph of the Will, the movie, produced by Leni Riefenstahl and the book Mein Kampf, by Adolf Hitler. Triumph of the Will is the film registry of the National Socialist Party in 1934, at the city of Nuremberg and Mein Kampf was written by Hitler in 1924 while He was in jail; the book aims to guide the members of the Nazi party. For this, the research resumes History by the Nazi’s rise using authors like Elias Canetti (1995 and Hannah Arendt (1989; we also study German film production by Siegrief Kracauer (1988. After, this work investigates the movies made by Riefenstahl from Ray Müller’s documentary (1993, and also by the book from Steven Bach (2008 and Riefenstahl’s autobiography (1991. This research constitutes as metodology the books by Mikhail Bakhtin (2010, Robert Stam (1992 and Jacques Durand (1973, to make the movie’s découpage we use Laurent Jullier and Michel Marie (2009. We separated sixteen movie scenes and they were compared between each other to investigate if the movie was made to be seen by all of the german people, to convince them about the Nazi’s ideal – originally present and described in Mein Kampf.

  10. VANET prototipa realizācija ar WiFi protokolu palīdzību

    OpenAIRE

    Osītis, Jurijs

    2016-01-01

    VANET tehnoloģija ļauj automobiļiem savā starpā komunicēt un informēt vienam otru par bīstamām situācijām uz ceļa. Veicot ES ceļu satiksmes negadījumu skaitu izpēti ir redzams, kā ir nepieciešama sistēma, kas spēj atbalstīt automobiļa vadītājus ceļā. Maģistra darba pētījuma mērķis ir izpētīt VANET tehnoloģiju, tās aktualitāti un iespējas, un izstrādājot prototipu izdarīt pētījumu, kurā pēc eksperimentu rezultātiem varēs izdarīt secinājumu, vai WiFi protokols spēj realizēt VANET tehnoloģiju ne...

  11. For another mise-en-scène: polyphony and affectivity in the movie Welcome

    Directory of Open Access Journals (Sweden)

    Eliane de Oliveira

    2014-12-01

    Full Text Available Traditionally known as a country of respect for human rights and political asylum in recent years France received notoriety by intolerance and expulsion of immigrants. Many of these situations are present in Welcome (Philippe Lioret, 2009 and provoked an intense social and political debate over immigration. The media visibility of different issues about the subject – which was possible because of the movie – ended with the expiration of the crime of solidarity, a law which punished french citizens who helped undocumented immigrants. To understand the presented situations by the movie, we use the studies of Zygmunt Bauman (1999, 2005, 2007 and 2009, contextualizing the movie and its production. Then, we discuss the imagetical construction process based on the concepts of Orientalism by Edward Said (2007, and Eurocentrism by Ella Shohat and Robert Stam (2006, and France’s specificities about racism, using the work of Albert Memmi (1993 and Michel Wieviorka (1998. The presence of the immigrant in Welcome was identified with polyphonic qualities, according to Mikhail Bakhtin’s perspective of polyphony. From the study of Luís Nogueira’s cinematographic specificities and the concepts of image, affection and visage by Gilles Deleuze (1985, 1995 we understand that the use of close ups aimed to produce an individualization of the immigrant and an affection for him. This way, we believe that Welcome cooperates in the sense of rising new possibilities of the immigrant’s fiction image, as well as about other minorities.

  12. Intertextualidade: considerações em torno do dialogismo

    Directory of Open Access Journals (Sweden)

    Ricardo Zani

    2003-06-01

    Full Text Available Este artigo tem a finalidade de contribuir para o reconhecimento do que se convencionou chamar por dialogismo, quando estudado por Mikhail Bakhtin através das obras do escritor francês François Rabelais e outros autores. As propriedades do dialogismo tornaram-se, posteriormente, focos de estudos para pesquisadores como Julia Kristeva, Robert Stam, Diana da Luz e José L. Fiorin, adquirindo também a denominação de intertextualidade e até mesmo de antropofagia, à medida em que um discurso, qualquer que seja este, remete-se a outros ao construir o seu nexo. Surgido no meio literário, o fenômeno dialógico ou intertextual pode ser aplicado à outras mídias como as artes plásticas, o cinema e a publicidade, enquanto estas travam um diálogo com diversas vozes (discursos, sendo perfeitamente reconhecidas, retrabalhadas e apresentando-se com desempenhos diferenciados de suas antecessoras. Como tal, o discurso dialógico é reconhecido quando uma relação entre vozes distintas é mostrada e não há uma necessidade de rompimento com seus modelos, influências e predecessores, ou seja, com a sua relação histórica.

  13. Simultaneous Thermal Analysis of Remediated Nitrate Salt Surrogates

    Energy Technology Data Exchange (ETDEWEB)

    Wayne, David Matthew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-05-13

    The actinide engineering and science group (MET-1) have completed simultaneous thermal analysis and offgas analysis by mass spectrometry (STA-MS) of remediated nitrate salt (RNS) surrogates formulated by the high explosives science and technology group (M-7). The 1.0 to 1.5g surrogate samples were first analyzed as received, then a new set was analyzed with 100-200mL 10M HNO3 +0.3 MHF added, and a third set was analyzed after 200 mL of a concentrated Pu-AM spike (in 10M HNO3 +0.3 MHF) was added. The acid and spike solutions were formulated by the actinide analytical chemistry group (C-AAC) using reagent-grade HNO3 and HF, which was also used to dissolve a small quantity of mixed, high-fired PuO2/ AmO2 oxide.

  14. A biocompatible micro cell culture chamber for culturing and on-line monitoring of Eukaryotic cells

    DEFF Research Database (Denmark)

    Stangegaard, Michael

    2006-01-01

    Visualisering af cellulære processer over længere tidsperioder har været besværliggjort af cellernes krav til varme, fugtighed og et fysiologisk pH balanceret medie. Fremskridt indenfor mikro teknologi har muliggjort fabrikation af miniaturiserede celle kultur anordninger der er i stand til...... at holde celler i live over længere tidsperioder I det foreliggende arbejde præsenteres et nyt perfusions baseret mikro celle dyrknings kultur kammer med integreret termisk overvågning og regulering. Kammeret opretholdt både dyrkning og on-line overvågning af både kræft celler såvel som stam celler over...... at dyrknings betingelserne i kammeret var sammenlignelige med dem i konventionelle celle kultur dyrknings flaske, hvis lys intensiteten på mikroskopet og omgivelserne blev minimeret mest muligt. Overflade modificeringer af den strukturelle fotoresist SU-8, der ofte bliver brugt til fabrikation af mikro kanaler...

  15. Die Tambaniprojek: ’n rekenaaranimasie van Die hebsugtige seekoei

    Directory of Open Access Journals (Sweden)

    Rita M.C. Swanepoel

    2012-11-01

    Full Text Available Hierdie artikel bied ’n ondersoek na en refleksie op die tegnieke en die produksieprosesse wat gebruik is in die omskakeling van ’n tradisionele Ngano-Venda-volksverhaal, Die hebsugtige seekoei, vanaf borduurwerk in ’n digitale animasiefilm. Die artikel word gerig deur ’n metode wat afgelei is uit ’n praktykgebaseerde navorsingsmodel vir skeppende uitsette. Hierdie navorsingsmodel omskryf wyses waarvolgens skeppende uitsette as geldige navorsingsopsies gereken kan word. Die metode bestaan uit die dokumentering van en refleksie ten opsigte van die projek in drie fases, naamlik pre-produksie, produksie en post-produksie. Die Tambani-borduurwerkprojek is ’n gemeenskapsuitreikingsinisiatief wat deur Ina le Roux van stapel laat loop is. Ngano is die versamelwoord vir tradisionele Vendavolksverhale. In hierdie artikel argumenteer ons dat rekenaaranimasietegnieke wel suksesvol geïmplementeer word in die digitale omskakeling van ’n Venda-volksverhaal wat oorspronklik uit ’n mondelinge tradisie stam. Ons demonstreer hierdie argument aan die hand van Christiaan van der Westhuizen se omskakeling van Die hebsugtige seekoei in ’n rekenaaranimasie.

  16. Determination of cloud coverage of Earth-like exoplanets by polarimetry

    Science.gov (United States)

    Rossi, Loïc; Stam, Daphne M.

    2016-10-01

    The properties of clouds in atmospheres of exoplanets will play a key role in the processes determining their radiative balance and climate.They also complicate the detection of chemical species in the atmospheres by flattening the spectra or by creating degeneracies between observables (Kitzmann et al. 2011, Line and Parmentier 2016).Polarimetry promises to be a powerful tool to detect and study exoplanets (Stam et al. 2004). The polarisation of the light scattered by the atmospheres of those planets contains a lot of information about the vertical structure of the atmosphere and about the composition of the clouds (Karalidi et al. 2012) and has already been very successful in the retrieval of atmospheric properties of Venus (Rossi et al. 2015, 2016 in prep).We will show that the degree of polarization of the light scattered by a cloudy exoplanet can be used to discriminate between different types of cloud coverage and to quantify the amount of cloud coverage on the planetary scale. We simulated the disk-integrated polarization of light scattered by exoplanets with various patchy cloud patterns, subsolar clouds and polar cusps. We show that flux and polarization can be used to differentiate between patchy and polar clouds. Observations at various wavelengths in the visible range and of different Stokes parameters would allow to differentiate between cloud coverage and cloud top altitudes.We also propose an observational strategy that could help to retrieve orbital parameters and percentage of cloud coverage with minor ambiguities.

  17. Starptautiskā uzņēmuma RED BULL mārketinga komunikāciju analīze klientu piesaistes kontekstā.

    OpenAIRE

    Litaunieks, Raimonds

    2016-01-01

    Bakalaura darba tēma ir “Starptautiskā uzņēmuma Red Bull mārketinga komunikāciju analīze klientu piesaistes kontekstā”. Bakalaura darba mērķis ir, pamatojoties uz teorijā sniegtajām atziņām un mērķgrupas aptaujas rezultātiem, izpētīt mārketinga stratēģijas kompleksu uzņēmumā Red Bull klientu piesaistes kontekstā. Bakalaura darba tēma ir aktuāla, jo uzņēmums Red Bull radīja enerģijas dzērienu tirgu un pašlaik ir tirgus līderis, kā arī uzņēmums ieguvis atpazīstamību, ne tikai pateicoties Red Bu...

  18. Galda spēļu vizuālā noformējuma izstrādes principi

    OpenAIRE

    2015-01-01

    Latvijas Univeritātes Pedagoģijas, psiholoģijas un mākslas fakultātes Izglītības zinātņu nodaļas Mākslas profesionālā bakalaura studiju programmas 4. kursa studenta Eduarda Frolova (Stud. apl. Nr. Ef11008) diplomdarbā „Galda spēļu vizuālā noformējuma izstrādes principi” tiek izpētīta galda spēļu vizuālā un spēles dizaina vēsture, attīstība un izcelsmes avoti. Diplomdarbs sastāv no trim daļām. Teorētiskajā daļā tiek apkopota informācija par piecām pazīstamākajām galda spēlēm cilvēces vēs...

  19. Atmosfēras piesārņojuma radītā riska novērtējums A/S „Ventamonjaks” ietekmes zonā

    OpenAIRE

    2013-01-01

    Amonjaka piesārņojums atmosfērā pilsētās saistīts ne tikai ar rūpniecisko uzņēmumu aktivitātēm, bet arī atkritumu apsaimniekošanu un autotransportu, tomēr nenoliedzami augstāka bīstamība piemīt tieši rūpnieciskajiem uzņēmumiem, kuri netīši avārijas rezultātā var radīt pat cilvēku dzīvībai bīstamas situācijas. Šādu uzņēmumu apzināšana un avārijriska novērtēšana ir viens no labas vides pārvaldības prakses pamatprincipiem. Tik lielā uzņēmumā kā A/S „Ventamonjaks” ir jābūt mobilizētam darīt vi...

  20. Ārstniecības personu inficēšanās risku cēloņi, vadība un risinājumi

    OpenAIRE

    Pleškāne, Viktorija

    2012-01-01

    Darbā veikta inficēšanās risku analīze, īpašu uzmanību pievēršot risku identifikācijai, vadībai un risku samazināšanas pasākumu izstrādāšanai. Vispārējā darba vides riska faktoru novērtēšana veikta, izmantojot Somijas 5 ballu matricu un izmantojot Somijas 5 ballu matricas modifikāciju „Matricu K-1”. Analīzes gaitā tika noskaidroti nozares trūkumi un problēmas, kas ietekmē sabiedrības un ārstniecības personas saslimšanas līmeni. Darba gaitā noskaidrots, kādas ir bīstamākās slimības apdraud ārs...

  1. Growth rates and morphological measurements of Porcupine caribou calves

    Directory of Open Access Journals (Sweden)

    Katherine L. Parker

    1989-06-01

    Full Text Available Body weights, leg lengths, and surface area were monitored for bottle-raised barren-ground caribou calves (Rangifer tarandus granti from the Porcupine herd up to 1 year of age. Body weights were compared with maternally-raised calves from the same cohort in the wild and from the Delta herd. A successful feeding regime for bottle-raising caribou calves is presented.Veksthastigheter og morfologiske mål hos Porcupine karibu-kalver.Abstract in Norwegian / Sammendrag: Kroppsvekter, visse knokkel-lengder og kropps-overflate areal ble målt hos flaske-oppfødde kalver av barren-ground karibu (Rangifer tarandus granti fra Porcupine-stammen opp til 1 års alder. Kroppsvekter ble sammelignet med normalt oppfødde kalver av samme type i det fri og fra Delta-stam-men. Det presenteres et vellykket system for flaske-oppforing av karibu-kalver.Porcupine-lauman karibuvasojen kasvunopeus ja morfologiset mitat.Abstract in Finnish / Yhteenveto: Porcupine -lauman pulloruokinnalla olleiden tundrakaribuvasojen ruumiinpainot, jalanpituu-det ja ruumiin pinta-alat mitattiin 1 vuoden ikäään saakka. Ruumiinpainoja verrattiin vastaaviin luonnon-oloissa kasvaneisiin saman lauman ja Delta -lauman vasoihin. Tutkimus kuvaa toimivan vasojen pulloruo-kintamenetelmän.

  2. Dzejniece Li Cjindžao (1084. - 1151.) un Sun dinastijas kulūra

    OpenAIRE

    Lapšina, Aelita

    2015-01-01

    Bakalaura darba tēma ir “Dzejniece Li Cjindžao (1084 - 1151) un Sun dinastijas kultūra”. Darbā tiek pētīta Sun dinastijas vēsture un kultūra, svarīgie notikumi un izgudrojumi, attiecības valstī un literatūras nozarē. Viena no pazīstamākajām tā laika personām ir dzejniece Li Cjindžao, par kuru plašāk ir aprakstīts darbā. Mūsdienās, pateicoties vairākām pētniecības programmām, mēs esam iepazinuši Ķīnu no daudzām pusēm, tomēr tik un tā paliek neizpētīti vairāku vēstures momentu un personu vēs...

  3. Approaches to Affective Computing and Learning towards Interactive Decision Making in Process Control Engineering

    Institute of Scientific and Technical Information of China (English)

    SU Chong; LI Hong-Guang

    2013-01-01

    Numerous multi-objective decision-making problems related to industrial process control engineering such as control and operation performance evaluation are being resolved through human-computer interactions.With regard to the problems that traditional interactive evolutionary computing approaches suffer i.e.,limited searching ability and human's strong subjectivity in multi-objective-attribute decision-making,a novel affective computing and learning solution adapted to human-computer interaction mechanism is explicitly proposed.Therein,a kind of stimulating response based affective computing model (STAM) is constructed,along with quantitative relations between affective space and human's subjective preferences.Thereafter,affective learning strategies based on genetic algorithms are introduced which are responsible for gradually grasping essentials in human's subjective judgments in decision-making,reducing human's subjective fatigue as well as making the decisions more objective and scientific.Affective learning algorithm's complexity and convergence analysis are shown in Appendices A and B.To exemplify applications of the proposed methods,ad-hoc test functions and PID parameter tuning are suggested as case studies,giving rise to satisfying results and showing validity of the contributions.

  4. Sabiedrisko attiecību darbības veidu izmantošana NVO komunikācijā ar sabiedrību. NVO „Dzīvnieku draugs" gadījuma analīze (2008.– 2010.)

    OpenAIRE

    Vucāne, Sarmīte

    2012-01-01

    Bakalaura darba tēma ir „Sabiedrisko attiecību darbības veidu izmantošana NVO komunikācijā ar sabiedrību. NVO „Dzīvnieku draugs” gadījuma analīze (2008. – 2010.)”. Darba mērķis ir izpētīt, kādus sabiedrisko attiecību darbības veidus nevalstiskā organizācija (NVO) „Dzīvnieku draugs” izmanto komunikācijā ar sabiedrību un vai to izmantošana ir vērsta uz organizācijas atpazīstamības, mērķu popularizēšanas, sabiedrības atbalsta un iesaistīšanās veicināšanu, kā arī pozicionē NVO „Dzīvnieku drau...

  5. Defining hypnosis as a trance vs. cooperation: hypnotic inductions, suggestibility, and performance standards.

    Science.gov (United States)

    Lynn, Steven Jay; Vanderhoff, Holly; Shindler, Kelley; Stafford, Jane

    2002-01-01

    We compared participants' responsiveness to a standard administration of a hypnotic suggestibility scale (CURSS; Spanos, Radtke, Hodgins, Bertrand, Stam, & Moretti, 1983) that defined the ability to experience hypnosis in terms of cooperation (SI; standard induction, N = 27) with a version of the same scale administered with all references to cooperation removed (CR; cooperation removed, N = 34) and with a version of the scale with the "induction" removed (NI; no induction, N = 35). In a fourth condition, participants were informed that the ability to experience hypnosis depended on their ability to achieve an altered state of consciousness or "trance" (AS; altered state, N = 33). Removing instructions for cooperation had an effect on objective (CR performance standards theory (Lynn & Rhue, 1991), participants who received the altered state set responded to fewer suggestions than did participants who received the standard induction (SI). Estimates of suggestions passed that were assessed before and after test suggestions were administered were, respectively, weakly to moderately correlated with objective and subjective measures of hypnotic suggestibility.

  6. Diálogos narrativos: as linhas de aproximação entre o audiovisual e os video games = Narrative dialogues: parallels between the audiovisual and video games

    Directory of Open Access Journals (Sweden)

    Barbosa, Afonso Manoel da Silva

    2014-01-01

    Full Text Available Pretendemos analisar as zonas de intersecção entre a linguagem audiovisual, sobretudo a cinematográfica, e a dos video games. Para tanto, examinamos o percurso desse processo observando as relações dialógicas estabelecidas entre esses dois campos discursivos a partir das franquias, adaptações e influências mútuas registradas em suas narrativas. Utilizaremos estudos sobre o dialogismo bakhtiniano a partir de Robert Stam e do próprio Mikhail Bakhtin, além de pesquisas sobre teoria da adaptação propostas por Linda Hutcheon. Como objeto central e produto dessas trocas entre dispositivos estéticos, traremos uma análise mais detalhada do jogo Red Dead Redemption (2009, Rockstar games, assinalando questões relacionadas à mise-en-scène do video game, utilizando os preceitos teóricos de David Bordwell e Kristin Thompson

  7. Mutācijas riska gēnos pacientiem ar atkārtotiem melanomas saslimšanas gadījumiem ģimenē

    OpenAIRE

    Veinalde, Rūta

    2011-01-01

    Melanoma ir bīstamākais ādas audzēja veids, kas attīstās pigmentu producējošo šūnu, melanocītu, nekontrolētas dalīšanās rezultātā. Melanomas kā multifaktoriālas saslimšanas attīstībā nozīme ir gan apkārtējās vides, gan ģenētisku riska faktoru mijiedarbībai. Galvenie līdz šim identificētie augsta riska melanomas jutības gēni ir CDKN2A, kurā mutācijas sastop apmēram pusē „melanomas ģimeņu” un CDK4, kurā mutācijas sastopamas mazāk kā 1% gadījumu. Latvijas populācijā līdz šim atrasta mutācija p.R...

  8. 冷应激引起鸡下丘脑基因表达谱差异分析%Identification of differentially expressed genes in hypothalamus of chicken during cold stress

    Institute of Scientific and Technical Information of China (English)

    陈兴勇; 李丽; 姜润深; 耿照玉

    2013-01-01

    为研究冷应激发生机制以及冷应激过程中下丘脑神经内分泌系统基因表达变化,选取28日龄淮南麻黄鸡为研究对象,采用全基因组表达谱芯片技术分析冷应激24 h后下丘脑组织差异表达基因.通过比较淮南麻黄鸡冷应激24 h前后下丘脑组织基因表达谱,表达倍数>3倍的基因共877个,其中下调基因334个,主要涉及HAAO、CHRNA9及STAM2等信号转导接头分子基因的低表达;上调基因543个,主要为CCK、NPY及其受体基因、CAMK2A、SST及TRH等基因.对差异表达基因参与的生物学过程分析可见,在冷应激24 h过程中,鸡下丘脑首先启动神经受体-配体相互作用,刺激鸡体产生采食欲望,随后启动脂质代谢途径以供应机体能量需求.在此过程中,Jak-STAT、Ca离子信号通路等一系列生物反应途径发生响应,以调节机体对寒冷应激的反应.差异表达基因的生物学通路分析为阐明鸡冷应激机理提供重要信息,差异表达基因分析有助于抗冷应激分子育种候选基因筛选.%In order to discover the mechanism of cold stress and identify differentially expressed genes in hypothalamus during cold stress,Huainan partridge chickens with 28 days, the Chinese indigenous breed, were selected for 24 hours cold stress and then hypothalamus was isolated and labeled by reverse transcription reaction for cDNA. The labeled cDNA was hybridized with cDNA microarray for scanning and image processing. The different gene expression profiling of hypothalamus was investigated from Huainan partridge chicken including 334 down-regulated genes and 543 up-regulated genes. As for these differentially regulated genes,HAAO,CHRNA9 and STAM2,etc. , which were involved in carbohydrate metabolism enzymes and signal transduction adapter, were significantly down-regulated, while genes like CCK,NPY and its receptor, CAMK2A, SST and TRH were significantly up-regulated. Through pathway analysis using Gene Ontology (GO

  9. PREFACE: Focus on Materials Nanoarchitectonics Focus on Materials Nanoarchitectonics

    Science.gov (United States)

    Aono, Masakazu

    2011-08-01

    On behalf of the International Center for Materials Nanoarchitectonics (MANA), I wish to express our gratitude for the publication of this special issue of Science and Technology of Advanced Materials (STAM), which highlights our recent research activities at MANA. In this preface, I would like to briefly describe the history and then outline the direction of research at MANA. In 2007, Japan's Ministry of Education, Culture, Sports, Science and Technology (MEXT) launched the World Premier International Research Center Initiative (WPI Program) to create several frontier research centers in Japan. The aim was to facilitate cutting-edge research by promoting the participation of leading scientists from around the world and by providing an attractive research environment. One of the six centers of the WPI Program is MANA, established at the National Institute for Materials Science (NIMS) in October 2007. The direction of research at MANA is symbolized by the term 'nanoarchitectonics', which is part of the name MANA. What is nanoarchitectonics? In the past quarter century, nanotechnology has made impressive advances and has become an important pillar in the development of new materials. However, to explore its full potential, nanotechnology needs to stay on the path of innovation. In particular, the conventional analytic view of nanotechnology must yield to a certain synthetic approach. This is conducive to creating new functions that can be exhibited by nanoscale structural units through mutual interactions, even though these functions are not present in the isolated units. We coined the term nanoarchitectonics (first used in the name of the 1st International Symposium on Nanoarchitectonics Using Suprainteractions (NASI-1), organized by the author and his colleagues at Tsukuba, Japan, in November 2000) to express this innovation of nanotechnology. More specifically, nanoarchitectonics is a technology system where the aim is arranging nanoscale structural units, which

  10. Los límites de la metáfora lingúística: implicaciones de una perspectiva corporeizada para la práctica investigadora e interventora Los límites de la metáfora lingúística: implicaciones de una perspectiva corporeizada para la práctica investigadora e interventora

    Directory of Open Access Journals (Sweden)

    Joan Pujol

    2003-01-01

    Full Text Available Perspectivas como el construccionismo social, el análisis del discurso o el análisis conversacional, han usado la metáfora lingüística paca defender una concepción de la realidad construida a través de la interacción lingüística. En el desarrollo de esta metáfora confluyen das herencias que han dado lugar a la omisión de la corporeidad cama forma de conocimiento y agencia. En primer lugar, la división cartesiana entre cuerpo y alma; de la cual resulta una visión del cuerpo o bien como “contenedor” del alma o como producto de una construcción cognitivo/social. En segundo lugar, la aposición “social” frente a «natural» excluyó al cuerpo (asignado al ámbito de lo natural como tema importante en debates sobre el orden y el control social. La metáfora lingüística enfatiza el polo de lo social-mental que lleva a un monismo antológico de carácter lingüístico. La corporeidad acaba siendo receptora de y disciplinada por el ámbito de lo discursivo (Sampson. 1996; Nightingale. 1999. Este trabajo recoge el renovado interés que la corporeidad está teniendo en ciencias sociales (i.e. Haraway, 1991 Turner 1992; Shilling 1993; Stam 1998; Burkitt, 1999 y explora las implicaciones que se derivan de la adopción de uno perspectiva corporeizada en las prácticas de investigación e intervención. Desde esta perspectiva se enfatiza el carácter productivo de las relaciones constituidas en procesos de investigación e intervención, entendidas como actividades que articulan múltiples posiciones corporeizadas desde las que se localizan y producen conocimientos.Perspectives such as social constructionism, discourse analysis or conversational analysis have used the linguistic metaphor to argue for an understanding of social reality as constructed through linguistic interaction. This metaphor inherits two conceptual legacies that lead to the omission of corporeality as a form of knowledge and agency. First, the Cartesian division

  11. Genome-wide copy number variation analysis in a Chinese autism spectrum disorder cohort

    Science.gov (United States)

    Guo, Hui; Peng, Yu; Hu, Zhengmao; Li, Ying; Xun, Guanglei; Ou, Jianjun; Sun, Liangdan; Xiong, Zhimin; Liu, Yanling; Wang, Tianyun; Chen, Jingjing; Xia, Lu; Bai, Ting; Shen, Yidong; Tian, Qi; Hu, Yiqiao; Shen, Lu; Zhao, Rongjuan; Zhang, Xuejun; Zhang, Fengyu; Zhao, Jingping; Zou, Xiaobing; Xia, Kun

    2017-01-01

    Autism spectrum disorder (ASD) describes a group of neurodevelopmental disorders with high heritability, although the underlying genetic determinants of ASDs remain largely unknown. Large-scale whole-genome studies of copy number variation in Han Chinese samples are still lacking. We performed a genome-wide copy number variation analysis of 343 ASD trios, 203 patients with sporadic cases and 988 controls in a Chinese population using Illumina genotyping platforms to identify CNVs and related genes that may contribute to ASD risk. We identified 32 rare CNVs larger than 1 Mb in 31 patients. ASD patients were found to carry a higher global burden of rare, large CNVs than controls. Recurrent de novo or case-private CNVs were found at 15q11-13, Xp22.3, 15q13.1–13.2, 3p26.3 and 2p12. The de novo 15q11–13 duplication was more prevalent in this Chinese population than in those with European ancestry. Several genes, including GRAMD2 and STAM, were implicated as novel ASD risk genes when integrating whole-genome CNVs and whole-exome sequencing data. We also identified several CNVs that include known ASD genes (SHANK3, CDH10, CSMD1) or genes involved in nervous system development (NYAP2, ST6GAL2, GRM6). Besides, our study also implicated Contactins-NYAPs-WAVE1 pathway in ASD pathogenesis. Our findings identify ASD-related CNVs in a Chinese population and implicate novel ASD risk genes and related pathway for further study. PMID:28281572

  12. Genetic parameters for milk yield and persistency in Carora dairy cattle breed using random regression model

    Directory of Open Access Journals (Sweden)

    Emanuela Tullo

    2014-12-01

    Full Text Available In tropical environments, lactation curves with lower peaks and higher persistency (PS might be desirable from both an economical and a physiological point of view. The objective of this study was to obtain genetic parameters for test day (TD yields, and PS for the tropical breed Carora and to compare these with results from a standard 305-d-milk yield animal model. Four random regression models (RRM were used on a dataset composed of 95,606 TD records collected in Venezuela and tested to find the best fitting the data. Estimated daily heritabilities for milk yields ranged from 0.21 to 0.30, with the lowest values around the peak of lactation. Lactation repeatabilities ranged from 0.50 to 0.56. Correlations between the breeding values obtained with the RRM and the lactation model currently used in Venezuela [single trait Animal Model (stAM] are quite high and positive (Pearson correlation=0.71 and Spearman correlation=0.72. Correlations between PS and 305-d-milk yield estimated breeding values (EBV ranged from -0.18 (PS as the deviation of daily productions in the interval 50-279 days in milk from a point at the end of lactation to 0.52 (PS as EBV difference between the second and the first stage of lactation. The use of PS indexes accounting for milk yield may allow the selection of individuals able to express their potential genetic values in tropical environment, without incurring in excessive heat stress losses.

  13. Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor β signaling

    Directory of Open Access Journals (Sweden)

    Pandey Akhilesh

    2004-01-01

    Full Text Available Abstract Background Transforming growth factor-βs (TGF-βs, bone morphogenetic proteins (BMPs and activins are important regulators of developmental cell growth and differentiation. Signaling by these factors is mediated chiefly by the Smad family of latent transcription factors. Results There are a large number of uncharacterized cDNA clones that code for novel proteins with homology to known signaling molecules. We have identified a novel molecule from the HUGE database that is related to a previously known molecule, AMSH (associated molecule with the SH3 domain of STAM, an adapter shown to be involved in BMP signaling. Both of these molecules contain a coiled-coil domain located within the amino-terminus region and a JAB (Domain in Jun kinase activation domain binding protein and proteasomal subunits domain at the carboxy-terminus. We show that this novel molecule, which we have designated AMSH-2, is widely expressed and its overexpression potentiates activation of TGF-β-dependent promoters. Coimmunoprecipitation studies indicated that Smad7 and Smad2, but not Smad3 or 4, interact with AMSH-2. We show that overexpression of AMSH-2 decreases the inhibitory effect of Smad7 on TGF-β signaling. Finally, we demonstrate that knocking down AMSH-2 expression by RNA interference decreases the activation of 3TP-lux reporter in response to TGF-β. Conclusions This report implicates AMSH and AMSH-2 as a novel family of molecules that positively regulate the TGF-β signaling pathway. Our results suggest that this effect could be partially explained by AMSH-2 mediated decrease of the action of Smad7 on TGF-β signaling pathway.

  14. Two-Dimensional Stable Isotope Fractionation During Aerobic and Anaerobic Alkane Biodegradation and Implications for the Field

    Science.gov (United States)

    El Morris, Brandon; Suflita, Joseph M.; Richnow, Hans-Hermann

    2010-05-01

    Quantitatively, n-alkanes comprise a major portion of most crude oils. In petroliferous formations, it may be possible to relate the loss of these compounds to the levels of biodegradation occurring in situ [1]. Moreover, it is important to develop indicators of alkane degradation that may be used to monitor bioremediation of hydrocarbon-impacted environments. Desulfoglaeba alkanexedens and Pseudomonas putida GPo1 were used to determine if carbon and hydrogen stable isotope fractionation could differentiate between n-alkane degradation under anaerobic and aerobic conditions, respectively in the context of the Rayleigh equation model [2]. Bacterial cultures were sacrificed by acidification and headspace samples were analyzed for stable isotope composition using gas chromatography-isotope ratio mass spectrometry. Carbon enrichment factors (bulk) for anaerobic and aerobic biodegradation of hexane were -5.52 ± 0.2‰ and -4.34 ± 0.3‰, respectively. Hydrogen enrichment during hexane degradation was -43.14 ± 6.32‰ under sulfate-reducing conditions, and was too low for quantification during aerobiosis. Collectively, this indicates that the correlation between carbon and hydrogen stable isotope fractionation (may be used to help elucidate in situ microbial processes in oil reservoirs, and during intrinsic as well as engineered remediation efforts. References 1. Asif, M.; Grice, K.; Fazeelat, T., Assessment of petroleum biodegradation using stable hydrogen isotopes of individual saturated hydrocarbon and polycyclic aromatic hydrocarbon distributions in oils from the Upper Indus Basin, Pakistan. Organic Geochemistry 2009, 40, (3), 301-311. 2. Fischer, A.; Herklotz, I.; Herrmann, S.; Thullner, M.; Weelink, S. A. B.; Stams, A., J. M.; Schloemann, M.; Richnow, H.-H.; Vogt, C., Combined carbon and hydrogen isotope fractionation investigations for elucidating benzene biodegradation pathways. Environ. Sci. Technol. 2008, 42, 4356-4363.

  15. ORLANDO AND THE GENDER REWRITTEN IN THE MOVIE

    Directory of Open Access Journals (Sweden)

    Edma Cristina Alencar de Gois

    2016-06-01

    Full Text Available O escritor Jorge Luís Borges dizia que reescrevemos obras literárias em vez de simplesmente nos alinharmos a determinadas ascendências literárias que moldariam novos textos. Inspirados nesta afirmativa que nega a mera influência direta, podemos pensar a versão cinematográfica pós-moderna como um outro locus de reescrituras, marcada por elementos como ironia, performatividade em cena e caráter excessivo no cenário e no figurino dos personagens. Tais características da produção cinematográfica colaboram para o questionamento das relações de gênero, sexo e corpos no filme Orlando, de Sally Potter (1992, inspirado no livro homônimo de Virgínia Woolf, Orlando - uma biografia (1928. Este artigo tem por objetivo perscrutar acréscimos ao texto literário e elementos próprios da pós-modernidade acionados pela produção de Potter, reconfigurando a narrativa original e, mais que isso, fundindo um novo texto. A discussão teórica será articulada a partir dos trabalhos a respeito da pós-modernidade de Frederic Jamenson (1984, Jean-François Lyotard (1993, e Andreas Huyssen (2010, do gênero como uma tecnologia de poder de Teresa de Lauretis (1994, e como construção performática de Judith Butler (2010, além das reflexões sobre representação e cinema de Robert Stam e Ella Shohat. Esperamos, por fim, contribuir para a análise de um caso concreto de aproximação entre Feminismo e Pós-Modernismo.

  16. Book Reviews

    Directory of Open Access Journals (Sweden)

    Book Review Editor, Barbara Hogenboom

    2014-03-01

    Full Text Available Rethinking Latin America: Development, Hegemony, and Social Transformation, by Ronaldo Munck (2013; reviewed by Peadar Kirby The Long, Lingering Shadow. Slavery, Race and Law in the American Hemisphere, by Robert J. Cottrol (2013; reviewed by Guno Jones Centering Animals in Latin American History, edited by Martha Few and Zeb Tortorici (2013; reviewed by Leopoldo Cavaleri Gerhardinger and Dannieli Firme Herbst River of Hope. Forging Identity and Nation in the Rio Grande Borderlands, by Omar S. Valério-Jiménez (2013; reviewed by Raymond Buve Enabling Peace in Guatemala: The Story of MINUGUA, by William Stanley (2013; reviewed by Dirk Kruijt Governing Indigenous Territories: Enacting Sovereignty in the Ecuadorian Amazon, by Juliet Erazo (2013; reviewed by Veronica Davidov Transnational Activism and National Movements in Latin America: Bridging the Divide, edited by Eduardo Silva (2013; reviewed by Roberta Rice Haiti’s New Dictatorship: The Coup, the Earthquake and the UN Occupation, by Justin Podur (2012; reviewed by Talitha Stam Cuba under Raúl Castro: Assessing the Reforms, por Carmelo Mesa-Lago y Jorge Pérez-López (2013; Cuban Economists on the Cuban Economy, editado por Al Campbell (2013; reseñado por Pablo Ospina Peralta Trumpets in the Mountains: Theater and the Politics of National Culture in Cuba, by Laurie A. Frederik (2012; reviewed by Jacqueline Loss Devoted to Death: Santa Muerte, the Skeleton Saint, by R. Andrew Chesnut (2012; reviewed by José Carlos G. Aguiar Foodscapes, Foodfields and Identities in Yucatán, by Steffan Igor Ayora-Diaz (2012; reviewed by Ester Katz

  17. Perchlorate reduction by microbes inhabiting oil reservoirs

    Science.gov (United States)

    Liebensteiner, Martin; Stams, Alfons; Lomans, Bart

    2014-05-01

    Microbial perchlorate and chlorate reduction is a unique type of anaerobic respiration as during reduction of (per)chlorate chlorite is formed, which is then split into chloride and molecular oxygen. In recent years it was demonstrated that (per)chlorate-reducing bacteria may employ oxygenase-dependent pathways for the degradation of aromatic and aliphatic hydrocarbons. These findings suggested that (per)chlorate may be used as oxygen-releasing compound in anoxic environments that contain hydrocarbons, such as polluted soil sites and oil reservoirs. We started to study perchlorate reduction by microbes possibly inhabiting oil reservoirs. One of the organisms studied was Archaeoglobus fulgidus. This extremely thermophilic archaeon is known as a major contributor to souring in hot oil reservoirs. A. fulgidus turned out to be able to use perchlorate as terminal electron acceptor for growth with lactate (Liebensteiner et al 2013). Genome based physiological experiments indicated that A. fulgidus possesses a novel perchlorate reduction pathway. Perchlorate is first reduced to chlorite, but chlorite is not split into chloride and molecular oxygen as occurs in bacteria. Rather, chlorite reacts chemically with sulfide, forming oxidized sulfur compounds, which are reduced to sulfide in the electron transport chain by the archaeon. The dependence of perchlorate reduction on sulfur compounds could be shown. The implications of our findings as novel strategy for microbiological enhanced oil recovery and for souring mitigation are discussed. Liebensteiner MG, Pinkse MWH, Schaap PJ, Stams AJM and Lomans BP (2013) Archaeal (per)chlorate reduction at high temperature, a matter of abiotic-biotic reactions. Science 340: 85-87

  18. An SH3 binding motif within the nucleocapsid protein of porcine reproductive and respiratory syndrome virus interacts with the host cellular signaling proteins STAMI, TXK, Fyn, Hck, and cortactin.

    Science.gov (United States)

    Kenney, Scott P; Meng, Xiang-Jin

    2015-06-02

    Porcine reproductive and respiratory syndrome virus (PRRSV) causes an economically important global swine disease, and has a complicated virus-host immunomodulation that often leads to a weak Th2 immune response and viral persistence. In this study, we identified a Src homology 3 (SH3) binding motif, PxxPxxP, that is conserved within the N protein of PRRSV strains. Subsequently, we identified five host cellular proteins [signal transducing adaptor molecule (STAM)I, TXK tyrosine kinase (TXK), protein tyrosine kinase fyn (Fyn), hematopoietic cell kinase (Hck), and cortactin] that interact with this SH3 motif. We demonstrated that binding of SH3 proteins with PRRSV N protein depends on at least one intact PxxP motif as disruption of P53 within the motif significantly reduced interaction of each of the 5 proteins. The first PxxP motif appears to be more important for STAMI-N protein interactions whereas the second PxxP motif was more important for Hck interaction. Both STAMI and Hck interactions with PRRSV N protein required an unhindered C-terminal domain as the interaction was only observed with STAMI and Hck proteins with N-terminal but not C-terminal fluorescent tags. We showed that the P56 residue within the SH3 motif is critical for virus lifecycle as mutation resulted in a loss of virus infectivity, however the P50 and P53 mutations did not abolish virus infectivity suggesting that these highly conserved proline residues within the SH3 motif may provide a selective growth advantage through interactions with the host rather than a vital functional element. These results have important implications in understanding PRRSV-host interactions.

  19. Tectonic, volcanic and human activity ground deformation signals detected by multitemporal InSAR techniques in the Colima Volcanic Complex (Mexico) rift

    Science.gov (United States)

    Brunori, C.; Norini, G.; Bignami, C.; Groppelli, G.; Zucca, F.; Stramondo, S.; Capra, L.; Cabral-Cano, E.

    2010-12-01

    The evolution of volcanoes is strictly related with their substratum and the regional tectonics. The link among morphology, geology and structure of volcanic edifices and the geological-structural characteristics of the basement is important to understand hazardous phenomena as flank eruptions and lateral collapses of volcanoes. The Colima Rift is an active regional structure, N-S oriented and more than 100 km long and 10 wide. This rift is filled by a ~1 km-thick sequence of quaternary lacustrine sediments, alluvium, and colluvium, mostly underling the about 3000 m thick volcanic pile of the Colima Volcanic Complex (CVC). In addition to the regional structures curved faults, roughly E-W oriented, are observed on the CVC edifice due to the spreading of the volcano moving southward on the weak basement. So in the CVC edifice and surrounding area we can observe the interaction of regional structures and volcanic ones due to the gravitational loading of the volcanic edifice on the weak substratum of the graben. To measure displacements due to magma movement at depth and interaction of regional structures and volcanic ones, SAR interferometry has proven to be a reliable method; however, andesitic stratovolcanoes like the CVC indeed,remain difficult to survey using this technique. The main causes are their specific geometry (steep topography), which induces strong tropospheric artefacts, environmental conditions (e.g., mainly vegetation, ash and/or snow cover), leading to a loss of coherency. In this work we try to detect deformations phenomena for the wide CVC using a robust multitemporal InSAR approach Differential Synthetic Aperture Radar Interferometry (DInSAR). We apply the Hooper (2008) DInSAR algorithm (StamPS/MTI) both to ENVISAT ASARr images acquired from 1993 to 2007 and to ALOS PALSAR (datasets from 2006 to 2010) in order to determine the deformation patterns in the CVC.

  20. Alice in Wonderland: uma tradução literária em imagens por Suzy Lee

    Directory of Open Access Journals (Sweden)

    Luis Carlos Girão

    2016-10-01

    Full Text Available Em 2015, um dos maiores clássicos da literatura infanto-juvenil moderna, Alice in Wonderland, completou 150 anos de lançamento. A obra-prima do controverso Lewis Carroll já foi traduzida e adaptada nos mais diversos meios de expressão artística. Em 2002, despontando na contemporânea literatura para crianças e jovens, Suzy Lee publicou sua tradução intersemiótica de Alice em livro-imagem. Análoga à ideia de Carroll referente a “um sonho dentro de um sonho”, Lee segue em sua publicação a ideia de “um livro dentro de um livro”, tornando ainda mais clara sua fonte de inspiração para a sua criação/recriação/adaptação. Objetivando realizar uma breve análise das obras literárias de Carroll e Lee, propomos um diálogo com os estudos de Roman Jakobson e os escritos do artista Julio Plaza no que se refere à tradução intersígnica, entre signos do código verbal para o código visual, para as versões de Alice in Wonderland aqui enunciadas. Sugerimos ainda uma aproximação com as ideias de Robert Stam sobre a adaptação literária, no caso da presente proposta, do livro ilustrado para o livro-imagem – narrativa composta por palavras para uma narrativa construída por imagens.

  1. Influence of Nitrogen Fertiliser on Winter Wheat Wholemeal Rheological Properties/ Slâpekïa Mçslojuma Ietekme Uz Ziemas Kvieðu Pilgraudu Miltu Reoloìiskajâm Îpaðîbâm

    Directory of Open Access Journals (Sweden)

    Liniņa Anda

    2014-08-01

    Full Text Available Izmçìinâjuma mçríis bija analizçt ziemas kvieðu pilngraudu miltu ûdens uzòemðanas spçju un mîklas fizikâlo îpaðîbu izmaiòas atkarîbâ no ðíirnes, slâpekïa (N papildmçslojuma (N60, N90, N120, N150 un laika apstâkïiem (2010. un 2011. gadâ tikko nokultiem graudiem un tos uzglabâjot (60, 120 un 360 dienas. Izmçìinâjumâ iekïautas ziemas kvieðu ðíirnes ‘Bussard’ un ‘Zentos’, kuras raksturojas ar augstas kvalitâtes pârtikas kvieðu graudiem. Ar Brabendera farinogrâfu (ICC 115/1 noteikta pilngraudu miltu ûdens uzòemðanas spçja un mîklas fizikâlâs îpaðîbas: mîklas veidoðanâs laiks, mîklas stabilitâtes laiks un mîklas izplûstamîbas pakâpe. Izmçìinâjumâ noskaidrots, ka pilngraudu miltu ûdens absorbcijas spçju un mîklas fizikâlâs îpaðîbas bûtiski ietekmç ðíirne, slâpekïa mçslojums un graudu uzglabâðanas laiks. Graudiem ar augstâku proteîna saturu ir labâkas pilngraudu mîklas fizikâlâs îpaðîbas. Bûtiskas atðíirîbas starp abu izmçìinâjuma gadu meteoroloìisko apstâkïu ietekmi uz ziemas kvieðu pilngraudu mîklas fizikâlajiem râdîtâjiem netika konstatçtas. Graudus uzglabâjot 60-360 dienas, bûtiski palielinâjâs pilngraudu mîklas veidoðanâs un stabilitâtes laiks, kâ arî palielinâjâs mîklas izplûstamîbas pakâpe, bet ûdens absorbcijas spçja bûtiski samazinâjâs. Ðíirnes ‘Bussard’ pilngraudu miltiem bija augstâka ûdens absorbcijas spçja, garâka mîklas stabilitâte un îsâka mîklas izplûstamîbas pakâpe. Farinogrâfa lîknes liecina, ka ðíirnes ‘Bussard’ pilngraudu miltiem mîklas veidoðanâs laiks ir vidçjs/ilgs, mîklas stabilitâte ilga/teicama. Savukârt ‘Zentos’ pilngraudu miltiem mîklas veidoðanâs laiks ir vidçjs, bet stabilitâte ilga. Vçrtçjot abu ðíiròu pilgraudu miltus pçc ûdens absorbcijas spçjas, tie ir stipri. Abâm izmçìinâjumâ iekïautajâm ðíirnçm proteîna saturs pilngraudu

  2. De olho no bruxo: o cinema brasileiro e a obra de Machado de Assis

    Directory of Open Access Journals (Sweden)

    Eugênio Vinci de Moraes

    2013-12-01

    Full Text Available RESUMOEste artigo apresenta um projeto emestágio inicial de pesquisa sobre as versões cinematográficas baseadas na obrade Machado de Assis. Há cerca de 30 filmes produzidos no Brasil, desde 1939 atéhoje, que partem dos contos e dos romances do escritor fluminense.  O objetivo deste trabalho é identificar,investigar e analisar as contribuições, as modalizações e as recriações que ocinema nacional realizou da obra de Machado de Assis no período anteriormente mcitado, por meio da análise estrutural e contextual. Para isso, será feito umlevantamento inicial dessas obras, uma catalogação de todos elementos queconcernem à produção do filme, para em seguida analisarem-se as leituras que osdiretores fizeram da obra de Machado. Aqui serão discutidas as premissas quefundamentarão essas análises. Entre elas, as ideias de adaptação, fidelidade eleitura e outras. As análises serão feitas com base em categorias narrativas,discutidas a partir de obras de Ismail Xavier, Robert Stam, Juracy A. Saraiva,entre outros.Palavras-chave: Machado de Assis. Cinema brasileiro. Narrativa. Adaptação. ABSTRACT This article presents a project in its early stage of research on thecinematographic versions based on the work of Machado de Assis. There have beenapproximately 30 films produced in Brazil since 1939 until today, based on thetales and novels written by the author. The objective of this work is toidentify, investigate and analyze the contributions, the modalizations and therecreations that the Brazilian cinema has done in relation to the work ofMachado de Assis in the period previously cited, by means of structural andcontextual analysis. For this reason, it will be made an initial survey ofthese works, a cataloguing of all elements concerning the film production.Then, it will be examined the interpretation by the film directors on the workof Machado de Assis. In this paper, the assumptions that sustain these analyzeswill be discussed

  3. Magnéli phases Ti{sub 4}O{sub 7} and Ti{sub 8}O{sub 15} and their carbon nanocomposites via the thermal decomposition-precursor route

    Energy Technology Data Exchange (ETDEWEB)

    Conze, S., E-mail: susan.conze@ikts.fraunhofer.de [Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Winterbergstr. 28, 01277 Dresden (Germany); Veremchuk, I. [Max-Planck-Institut für Chemische Physik fester Stoffe, Nöthnitzer Straße 40, 01187 Dresden (Germany); Reibold, M. [Technical University of Dresden, Zum Triebenberg 50, 01328 Dresden (Zaschendorf) (Germany); Matthey, B.; Michaelis, A. [Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Winterbergstr. 28, 01277 Dresden (Germany); Grin, Yu. [Max-Planck-Institut für Chemische Physik fester Stoffe, Nöthnitzer Straße 40, 01187 Dresden (Germany); Kinski, I. [Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Winterbergstr. 28, 01277 Dresden (Germany)

    2015-09-15

    A new synthetic approach for producing nano-powders of the Magnéli phases Ti{sub 4}O{sub 7}, Ti{sub 8}O{sub 15} and their carbon nanocomposites by thermal decomposition-precursor route is proposed. The formation mechanism of the single-phase carbon nanocomposites (Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C) from metal–organic precursors is studied using FT-IR, elemental analysis, TG, STA-MS and others. The synthesis parameters and conditions were optimized to prepare the target oxides with the desired microstructure and physical properties. The electrical and transport properties of Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C are investigated. These nano-materials are n-type semiconductors with relatively low thermal conductivity in contrast to the bulk species. The nanostructured carbon nanocomposites of Magnéli phases achieve a low thermal conductivity close to 1 W/m K at RT. The maximum ZT{sub 570} {sub °C} values are 0.04 for Ti{sub 4}O{sub 7}/C powder nanocomposite and 0.01 for Ti{sub 8}O{sub 15}/C bulk nanocomposite. - Graphical abstract: From the precursor to the produced titanium oxide pellet and its microstructure (SEM, TEM micrographs) as well as results of phase and thermoelectric analyses. - Highlights: • Magnéli phases Ti{sub 4}O{sub 7}/Ti{sub 8}O{sub 15} via thermal decomposition-precursor route is proposed. • The formation mechanism of the nanocomposites Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C are investigated. • Microstructure of Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C are examined. • The electrical and transport properties of Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C are investigated. • The maximum figure of mertit ZT{sub 570} {sub °C} of Ti{sub 4}O{sub 7}/C and Ti{sub 8}O{sub 15}/C are 0.01 and 0.04.

  4. 体育疗法在涉核特勤疗养中的应用

    Institute of Scientific and Technical Information of China (English)

    闫明启; 颜晗

    2015-01-01

    在现代高技术战争背景及各种复杂环境条件下,涉核官兵所必需具有的坚强意志和强健体魄是顺利完成各项军事任务的保证。如何有效提升涉核特勤疗养人员的体能状况仍然有待进一步研究探讨。本文从涉核特勤疗养人员的特点、涉核特勤疗养的必要性、体育疗法的组织与实施以及存在问题和改进措施等方面进行阐述,为如何将体育疗法合理应用于涉核特勤疗养人员体能训练提供一些有益的内容和参考。%In the background of m odern high technology w ar and com plex environm ental conditions,nucleus-in-volved officers and m en m ust have a strong w ill and a robust physique,w hich can ensure the successful accom plish-m ent of various m ilitary tasks.It still needs further research and discussion about how to effectively im prove the physi-cal stam ina status of the nucleus-involved special service convalescents.T his paper carries on the elaboration from the follow ing aspects such as the characteristics of nucleus-involved special service convalescents,the necessity of special service recuperation,the organization and im plem entation of physical exercise therapy,and the existing problem s and im provem ent m easures,w hich provides som e useful inform ation and reference on how to m ake reasonable application of physical exercise therapy for the physical training of nucleus-involved special service convalescents.

  5. The Effect of Information Disclosure Quality on Liquidity Risk%信息披露质量对股票流动性风险的影响分析

    Institute of Scientific and Technical Information of China (English)

    刘维奇; 李丹丰

    2014-01-01

    预测和防范股票的流动性风险对投资决策具有重要的指导意义。基于Pastor和Stambaugh(2003)的测度,利用滚动回归法度量股票的流动性风险,以投资者决策可用信息为切入点,从市场交易信息、公司财务报表和证券分析师预测三个视角,考察了信息披露质量对股票流动性风险的影响。结果表明,信息披露质量高的公司其股票未来的流动性风险较低。分析师预测信息可以较好地甄别公司信息披露质量。此外,信息披露质量对股票流动性风险的负向预测能力与市场流动性新息的强弱呈正向关系,且在市场流动性恶化期内尤为显著。%It is important for securities investors to prevent and manage liquidity risk.Basing on Pastor&Stam-baugh (2003) measure, we use rolling regression to compute liquidity risk.From the perspective of the available information for investor decision -making, we use market trading information , financial statements and analysts ’ forecast to investigate the effect of information disclosure quality on liquidity risk.The empirical results show that higher information quality is associated with lower liquidity risk.Contrasting the three measures proxies of informa-tion disclosure quality , we find that investors using analysts ’ forecast can better identify information disclosure quality.In addition , the negative effect of information disclosure quality on liquidity risk is positive and significant with the degree of market liquidity innovation , especially during a period of deterioration in market liquidity.

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Harry A. Poeze

    1985-10-01

    Full Text Available - J. van Baal, B. van Norren, Socio-culturele structuur en innovatie: een structuur-vergelijkend onderzoek naar adoptie van family-planning in de periode 1969-1973 door Sundanese echtparen in twee rurale gemeenschappen op West-Java. Dissertatie Landbouwhogeschool Wageningen, 1985. 533 pp. - Pierre Brocheux, Andrew Turton, History and peasant consciousness in South East Asia, Senri Ethnological studies no. 13, National Museum of Ethnology, Osaka. 1984, 420 pp., Shigeharu Tanabe (eds. - I.H. Enklaar, J. Verkuyl, Gedenken en verwachten, mémoires, Kampen: J.H. Kok, 1983, 348 pp. - J. van Goor, D.J. Roorda, Overzicht van de Nieuwe Geschiedenis; De algemene geschiedenis van het einde der middeleeuwen tot 1870 (Groningen 1983; dez. Nieuwe Geschiedenis in teksten; Werkboek (Groningen 1984. - R. Hagesteijn, H.D. Kubitscheck, Südost Asien: Völker und Kulturen, Berlin: Akademie-Verlag, 1984. - C.H. van Nieuwenhuijsen-Riedeman, Florence Weiss, Kinder schildern ihren Alltag. Die stellung des kindes om ökonomischen System einer Dorfgemeinschaft in Papua New Guinea (Palimbei, Iatmul, Mittelsepik. [Children narrate their daily life. The child’s role in the economic system of a village community in Papua New Guinea (Palimbei, Iatmul, Middle Sepik ],Basler Beiträge zur Ethnologie band 21, Basel: Ethnologisches Seminar der Universität und Museum für Völkerkunde, 1981. - Harry A. Poeze, Joop Morriën, `Aroen’; Jan Stam, rebel in Indonesië en Nederland, Amsterdam: Pegasus, 1984, 159 pp. - P.H. Pott, Jeanne de Loos-Haaxman, De Franse Schilder Ernest Hardouin in Batavia, Leiden: Brill, 1982, 51 pp., ills. - Harry A. Poeze, Uit het archief van Arthur Lehning, Amsterdam: Van Gennep 1984. - W.G.J. Remmelink, P.B.R. Carey, Babad Dipanagara; An account of the outbreak of the Java War (1825-1830, The Malaysian branch of the Royal Asiatic Society - Monograph No. 9, Kuala Lumpur, 1981, LXXIII + 343 pp., 2 maps, 6 illustrations.

  7. Rosuvastatin as a potential preventive drug for the development of hepatocellular carcinoma associated with non-alcoholic fatty liver disease in mice.

    Science.gov (United States)

    Yokohama, Keisuke; Fukunishi, Shinya; Ii, Masaaki; Nakamura, Ken; Ohama, Hideko; Tsuchimoto, Yusuke; Asai, Akira; Tsuda, Yasuhiro; Higuchi, Kazuhide

    2016-11-01

    Hepatocellular carcinoma (HCC) represents approximately 85% of all primary liver cancer cases. Non-alcoholic fatty liver disease (NAFLD) is one of the risk factors for HCC. NAFLD occurs in patients with components of metabolic syndrome, such as type 2 diabetes mellitus, obesity, hypertension and hyperlipidemia. Therefore, hyperlipidemia also represents a patient population at risk for HCC that can readily be identified. Rosuvastatin, a 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitor, has exhibited a more potent affinity for the active site of HMG-CoA reductase than other statins. In addition, the hepatic uptake of rosuvastatin in rats has been found to be more selective and efficient than that with other drugs. Furthermore, the cytoprotective effects of rosuvastatin against ischemic injury have been clearly reported. Thus, in this study, we aimed to determine the role of rosuvastatin as a preventive drug in HCC associated with NAFLD. STAM mice, which developed HCC from NAFLD by being fed a high-fat diet (HFD), were divided into a group in which a HFD was given to the mice for 15 weeks (n=8) and another in which a HFD supplemented with 0.00125% rosuvastatin was given to the mice for 15 weeks (n=8). Rosuvastatin inhibited the development of hepatic tumors in the mice with NAFLD induced by a specific diet both macroscopically and histologically. Rosuvastatin significantly decreased the expression levels of pro-inflammatry cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-6 and transforming growth factor (TGF)-β1. Tumor aggressiveness is mediated by angiogenic factors. Therefore, we examined the hepatic mRNA expression of vascular endothelial growth factor receptor (VEGFR), epidermal growth factor receptor (EGFR) and platelet-derived growth factor (PDGF). The hepatic expression of these factors significantly decreased in the rousvastin-fed mice. Our results thus suggest rosuvastatin that prevents carcinogenesis

  8. A behavioural intervention increases physical activity in people with subacute spinal cord injury: a randomised trial

    Directory of Open Access Journals (Sweden)

    Carla FJ Nooijen

    2016-01-01

    intervention was effective in eliciting a behavioural change toward a more active lifestyle among people with subacute spinal cord injury. Trial registration: NTR2424. [Nooijen CFJ, Stam H, Bergen MP, Bongers-Janssen HMH, Valent L, van Langeveld S, Twisk J, Act-Active Research Group, van den Berg-Emons RJG (2016 A behavioural intervention increases physical activity in people with subacute spinal cord injury: a randomised trial. Journal of Physiotherapy 62: 35–41

  9. Foreword: Focus on Superconductivity in Semiconductors

    Directory of Open Access Journals (Sweden)

    Yoshihiko Takano

    2008-01-01

    Full Text Available Since the discovery of superconductivity in diamond, much attention has been given to the issue of superconductivity in semiconductors. Because diamond has a large band gap of 5.5 eV, it is called a wide-gap semiconductor. Upon heavy boron doping over 3×1020 cm−3, diamond becomes metallic and demonstrates superconductivity at temperatures below 11.4 K. This discovery implies that a semiconductor can become a superconductor upon carrier doping. Recently, superconductivity was also discovered in boron-doped silicon and SiC semiconductors. The number of superconducting semiconductors has increased. In 2008 an Fe-based superconductor was discovered in a research project on carrier doping in a LaCuSeO wide-gap semiconductor. This discovery enhanced research activities in the field of superconductivity, where many scientists place particular importance on superconductivity in semiconductors.This focus issue features a variety of topics on superconductivity in semiconductors selected from the 2nd International Workshop on Superconductivity in Diamond and Related Materials (IWSDRM2008, which was held at the National Institute for Materials Science (NIMS, Tsukuba, Japan in July 2008. The 1st workshop was held in 2005 and was published as a special issue in Science and Technology of Advanced Materials (STAM in 2006 (Takano 2006 Sci. Technol. Adv. Mater. 7 S1.The selection of papers describe many important experimental and theoretical studies on superconductivity in semiconductors. Topics on boron-doped diamond include isotope effects (Ekimov et al and the detailed structure of boron sites, and the relation between superconductivity and disorder induced by boron doping. Regarding other semiconductors, the superconducting properties of silicon and SiC (Kriener et al, Muranaka et al and Yanase et al are discussed, and In2O3 (Makise et al is presented as a new superconducting semiconductor. Iron-based superconductors are presented as a new series of high

  10. Language Development or Language Corruption? The Case of Loan-words in Isichazamazwi SesiNdebele

    Directory of Open Access Journals (Sweden)

    Cornelias Ncube

    2011-10-01

    Ndebele (voortaan ISN deur veral te kyk na hul aanvaarding en/of nieaanvaarding deur die teikengebruikers van ISN. In Zimbabwe deel Ndebele dieselfde taalomgewing met Engels, Sjona en die offisiële minderheidstale soos Kalanga, Tonga en Nambya. 'n Historiese erfenis verbind dit ook met die Ngunisustertale soos Zoeloe en Xhosa wat in Suid-Afrika gepraat word. Vir die keuse van trefwoorde in ISN, het die Ndebele- leksikografiese eenheid die frekwensielysmetode gebruik deur die woorde te lemmatiseer wat die meeste in die korpus aangetref is. Hierdie metode het onvermydelik die opname van leenwoorde in die ISN toegelaat met die gevolglike openbare protes. Die artikel is in twee breë afdelings verdeel. Die eerste afdeling gee 'n algemene oorsig van die kom-mentaar van die gebruikers van ISN op die insluiting van leenwoorde in die woordeboek. Die houding teenoor leenwoorde in die ISN wissel by verskillende ouderdomsgroepe, met die jonger geslag wat hulle vrylik as deel van die Ndebeleleksikon aanvaar in teenstelling tot die ouer geslag. Die tweede afdeling ontleed die regverdiging deur die redakteurs van ISN vir die lemmatisering van leenwoorde teenoor die beskouings van die teikengebruikers. Voorbehoude teen die leenwoor-de in ISN gaan verder as leksikografiese beginsels. Vooraan is die gebruikers se houding teenoor die brontaal. Taalhoudings in Zimbabwe is hoofsaaklik die gevolg van die sosiopolitieke en eko-nomiese sterkte wat die verskillende stam- of etniese groepe in die land kenmerk. Die artikel sluit af met 'n bespreking van moontlike oplossings vir die probleem van leenwoorde wat in die toe-komstige Gevorderde Ndebelewoordeboek opgeneem sal word.

    Sleutelwoorde: LEENWOORDE, KULTURELE ONTLENING, DIALEKONTLENING, LEK-SIKON, OORNAME, TAALPURISME, TAALEMANSIPASIE

  11. 大型机器人冲压生产线多软件联合仿真%Multi-software Co-simulation for a Large Robotic Automatic Stamping Production Line

    Institute of Scientific and Technical Information of China (English)

    邱雪松; 肖超; 谭候金; 侯雨雷; 周玉林

    2016-01-01

    For the rapid design of large robotic automatic stamping production line,based on inter-face technology and multi-software co-simulation,a method was proposed to meet design require-ments,such as kinematics,dynamics,stiffness and so on.By Dynaform software,sheet metal form-ing process was simulated,and dynamic load curve was captured and loaded into virtual prototype to approximate real load.Key components were changed into flexible bodies by ANSYS and were impor-ted into ADAMS to replace corresponding rigid bodies and a rigid-flexible coupling virtual stamping production line was established.Processing vehicle side panels were taken as an example,and the mathematical models of kinematics and dynamics of main press in the stamping production line were established.The energy consumption index and safety- efficiency balance index were proposed to eval-uate the comprehensive performance of the system.The rigid-flexible coupling virtual prototype simu-lation results were compared with theoretical calculations and multi-body virtual prototype simulation results.The analysis results show that rigid-flexible model can improve the simulation accuracy,may be closer to the real process and possess theoretical direction significance for overall design of stam-ping production line,the key parameter selection,on-site installation and commissioning.%为快速设计研制大型机器人冲压生产线并满足运动学、动力学、刚度等方面的设计要求,提出基于接口技术的多软件联合仿真策略:利用Dynaform软件模拟板料冲压成形过程、捕获动态负载曲线,并加载到压机上用于逼近真实载荷;利用ANSYS软件对关键部件作柔性化处理并导入ADAMS中替换相应的刚体,建立刚柔耦合的冲压线虚拟样机.以加工汽车侧围板为例,建立冲压线中主压机的运动学和动力学数学模型,提出系统能耗指标和安全效率平衡系数两个综合性能评价指标.将刚柔耦合虚拟样机的仿真

  12. Are there other axillary lymph node metastasis than positive sentinel lymph nodes containing micrometnstmes and isolated tumor cells in patients with breast csncer%乳腺癌患者腋窝前哨淋巴结微转移及孤立癌细胞的评价

    Institute of Scientific and Technical Information of China (English)

    周雷; 宋新; 鲁瑶; 刘治滨; 李启东; 王文跃; 王正康; 贾振庚; 高島茂树

    2008-01-01

    目的 评价连续切片及免疫组化技术在乳腺癌前哨淋巴结(SLN)转移诊断中的价值,探讨微转移和孤立癌细胞的临床意义.方法 对80例腋窝淋巴结阴性的乳腺癌患者,用99mTc-SC和异硫蓝联合法进行前哨淋巴结活检(SLNB),对所有SLN和非SLN进行常规HE染色及免疫组织化学分析.结果 78例(97.5%)成功检出SLN,其中76.5%的SLN同位素和染料检查均为阳性.32例(41%)SLN转移阳性,其中13例(40.6%)为微转移.共有14例(43.8%)患者SLN是惟一阳性的淋巴结.SLN预测腋窝状态的敏感性、特异性和准确性分别为96.9%,100%和98.7%.SLN转移的患者,其SLN之外的转移率明显高于仅有微转移的患者(78.9%vs.23.1%).结论 连续切片及免疫组化技术是乳腺癌SLN转移诊断的敏感方法.仅有SLN微转移患者的SLN之外的腋窝淋巴结转移率低,但其预后意义及对手术方案的影响尚待进一步研究.%Objective The purpose of this study was to assess the value of serial sectioning and immunohistoehemistry(IHC)for the diagnosis of senfinel lymph node(SLNs)metastases in patients with breast cancer,and to evaluate the significance of mierometastases and isolated tunlor cells(ITCs)in the SLNs. Methods Eighty pailents with clinically node-negative breast cancer underwent SLN biopsy with both99mTc-labeled sulfur colloid and iBosulfan blue dye for SLN identification.All SLNS and non-SLNs were evalnated with standard H&E stain and IHC analysis. Results SLNs were successfully identified in 78 of 80 patients(97.5%),the isotope/blue dye concordanee rate was 76.5%for all SLNs.Thirty two patients (41%)had histologically positive SLNs,and 13(40.6%)of these patients hod SLNS with micrometastatic disease.In 14(43.8%)of these patients,the SLNs were the only nodes involved.The sensitivity,specificity and accuracy of SLN biopsy in predicting axillary node stams were 96.9%,100%and 98.7%,reslaeetively.Patients with positive SLNs metastasis had a markedly

  13. Empirical study of the characteristics of the pedestrians’ velocity in crowded places based on cross-correlation algorithm%基于互相关算法的人员密集场所人群运动速度特征研究

    Institute of Scientific and Technical Information of China (English)

    王嘉悦; 翁文国; 张小乐

    2014-01-01

    Study on the velocity characteristics of pedestrian behaviors can predict pedestrian movement trend dur -ing real mass events in crowded places .It is very important to warn the abnormal pedestrian behaviors and prevent the occurrence of excessive crowd or even stampede , thus ensure the large-scale mass activities successfully and safely .In this paper , empirical study was conducted on the large scale and high density of people ’ behaviors in the core area of a domestic major city , by a cross-correlation algorithm .The velocity of pedestrian movement was ex-tracted at different speeds .In addition, the average velocities of pedestrians were compared with four passages to the scenic spot , to investigate the motion characteristics of pedestrians .The results showed that the velocities on u-nidirectional path were large and the movement directions were nearly parallel to the boundaries .However , the ve-locities on two-way passage were changed due to the damping effect of the crowd .Some effective suggestions are thus proposed for the organization and the crowd evacuation of large-scale mass activities .The results can also pro-vide some theoretical information to risk prevention and control for stampede , make the emergency plan for stam-pede and the safety scheme for crowd activities .%研究人群密集场所的人群运动速度特征可以预测人群的运动趋势,在大型活动组织过程中可以对异常人群运动做出预警,避免过度的拥挤及踩踏事件的发生,保证大型群体性活动的安全顺利开展。利用国内某重要城市核心区公共场所人群运动的视频图像,通过互相关算法提取该场所人群的运动速度,并进一步比较通往景区的四条不同路径上人群运动速度的差异性,分析其人群运动特征。分析结果表明单向通道的人群运动速度较大且运动方向基本与通道的两侧边界平行,而双向通道中由于人群中阻尼效应的影响,人

  14. 英国《临床康复》目次(2001年第15卷第1期)Contents in British:《Clinical%Contents in British:《Clinical Rehabilitation》(Volume 15, Issue 1, January 2001)

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@·Editorial, Research into the black box of rehabilitation: the risks of a Type III error Wade D.T.   ·Electrical stimulation for preventing and treating post? stroke shoulder pain: a systematic Cochrane review Price C.I.M., Pandyan A.D.   ·Exercise therapy for arm function in stroke patients: a systematic review of randomized controlled trials Lee v.d.J.H., Snels I.A.K.,Beckerman H.,Lankhorst G.J.,Wagenaar R.C.,Bouter L.M.   ·The COSTAR wheelchair study: a two? centre pilot study of self? propulsion in a wheelchair in early stroke rehabilitation Barrett J.A., Watkins C.,Plant R.,Dickinson H.,Clayton L.,Sharma A.K.,Reston A.,Gratton J.,Fall S.,Flynn A.,Smith T.,Leathley M.,Smith S.,Barer D.H.COSTAR   ·A multicentre randomized controlled trial of leisure therapy and conventional occupational therapy after stroke Parker C.J., Gladman J.R.F.,Drummond A.E.R.,Dewey M.E.,Lincoln N.B.,Barer D.,Logan P.A.,Radford K.A.   ·The effect of a hinged ankle foot orthosis on hemiplegic gait: objective measures and users' opinions Tyson S.F., Thornton H.A.   ·Patterns of hemiparesis recovery in lacunar and partial anterior circulation infarct stroke syndromes Smith J., Brotheridge S.,Young J.   ·Unpacking the black box of nursing and therapy practice for post? stroke shoulder pain: a precursor to evaluation Pomeroy V.M., Niven D.S.,Barrow S.,Faragher E.B.,Tallis R.C.   ·Functional level of young adults with cerebral palsy Dussen L.v.a.n.d.e.r., Nieuwstraten W.,Roebroeck M.,Stam H.J.   ·Mobility of people with lower limb amputations: scales and questionnaires: a review Rommers G.M., Vos L.D.W.,Groothoff J.W.,Eisma W.H.   ·Adapting the Nottingham Health Profile for use in people with severe physical disabilities Post M.W.M., Gerritsen J.,Leusen N.v.,Paping M.A.,Prevo A.J.H.   ·研究康复的黑盒子—第三种错误的危险性   ·电刺激防治脑卒中后的肩痛:Cochrane系统性评估   ·脑卒中病人手

  15. Associations between Manual Abilities, Gross Motor Function, Epilepsy, and Mental Capacity in Children with Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Ewa GAJEWSKA*

    2014-04-01

    children with cerebral palsy. A population-based study of 359 children. BMC Musculoskeletal Disorders 2007;21:50.Bax MC, Keith Brown J. The spectrum of disorders known as CP. In: Scrutton D, Damiano D, Mayston M, editors. Management of the Motor Disorders of Children with CP. Clinics in Developmental Medicine London: Mac Keith Press; 2004. p. 83-140.Kwong KL, Wong SN, So KT. Epilepsy in children with cerebral palsy. Pediatr Neurol 1998 ;19:31-6.Odding E, Roebroeck ME, Stam HJ. The epidemiology of cerebral palsy: incidence, impairments and risk factors. Disabil Rehabil 2006;28(4:183-91.Sugiura C, Shiota M, Ieshima A, Ohno K. [Epilepsy in patients with cerebral palsy--analysis of frequency and clinical prognosis]. No To Hattatsu 2003;35(6:478-83.McLellan A. Epilepsy – an additional risk factor for psychological problems in cerebral palsy. Dev Med Child Neurology 2008;50(10:727.Kulak W, Sobaniec W, Smigielska-Kuzia J, Kubas B, Walecki J. A comparison of spastic diplegic and tetraplegic cerebral palsy. Pediatr Neurol 2005;32(5:311-7.Rossman BS, Ashwal S. Evaluation of the child with cerebral palsy. Seminars in Pediatr Neurol 2004;11(1:47-57. 

  16. EDITORIAL: Roberts Prize for the best paper published in 2012 Roberts Prize for the best paper published in 2012

    Science.gov (United States)

    Cherry, Simon; Ruffle, Jon

    2013-08-01

    . 57 2829 Scott A J D, Kumar S, Nahum A E and Fenwick J D 2012 Characterizing the influence of detector density on dosimeter response in non-equilibrium small photon fields Phys. Med. Biol. 57 4461 Stam M K, Crijns S P M, Zonnenberg B A, Barendrecht M M, van Vulpen M, Lagendijk J J W and Raaymakers B W 2012 Navigators for motion detection during real-time MRI-guided radiotherapy Phys. Med. Biol. 57 6797 Xia T, Alessio A M, De Man B, Manjeshwar R, Asma E and Kinahan P E 2012 Ultra-low dose CT attenuation correction for PET/CT Phys. Med. Biol. 57 309 Yamaguchi M et al 2012 Beam range estimation by measuring bremsstrahlung Phys. Med. Biol. 57 2843 For more information on this article, see medicalphysicsweb.org

  17. 不同移植途径对大鼠骨髓干细胞迁移至肝脏及分化的影响%Study on migration and differentiation of rat bone marrow stem cells to hepatocytes under three different routes of transplantation

    Institute of Scientific and Technical Information of China (English)

    耿莹; 韩明子; 洪钰; 金世柱; 孙立影

    2008-01-01

    Objective To observe the migration and differentiation of rat bone rnarmw stem cells to liver under three different routes of transplantation.Methods Intragastric administration was taken to 30 SD rats with CCl4-AAF by which the acute hepatic injured models were made.Bone marrow mononuclear cells which were lsolated from bone marrow with lymphocyte separating medium were labeled by PKH26.The rats were divided into 3 groups.The rats in portal vein-transDlanted group anesthetized were autotransplanted with 0.4 ml bone marrow stem cells suspension via portal vein.The rats in tail vein-transplanted group were autotransplanted with 0.4 ml bone marrow stam cells suspenslon via tail vein.The central sections were made on the abdomen of the rats in hepatic artery-transplanted group to expose the hepatic artery.The distal end of the gastroduodenal arterv was ligated and the blood flow of the common hepatic artery was cut by clamp 0.4 ml bone marrow stem cells suspension was injected In front of ligation of the gastroduodenal artery.Two weeks after transPlantion,the liver tissues were taken from the rats of every group and cut into frozen sections.The immunohistochemistry staining by fluorescein isothiocyanate was done to the sections for detection of the PKH26-labeled cells and the expression of albumin and CK18.Results Red fluorescence of PKH26 in the sections of every group was observed.The number of PKH26-labeled cells in the liver of portal vein-transplanted group,tail vein-transplanted group and hepatic artery-transplanted group was(58.0±2.67),(57.8±3.04)and(58.3±3.52)respectively.There was no significant difference between the groups(P>0.05).The sections in every group expressed albumin and CK18(green fluorescence).The cells expressing red and green fluorescence at the same time were observed under fluorescence microscope(the yellow fluorescence=red fluorescence+the green fluorescence).Conclusion Under injured liver status,bone marrow stem cells of three groups

  18. Co-suppression in transgenic Petunia hybrida expressing chalcone synthase A (chsA)

    Institute of Scientific and Technical Information of China (English)

    LI; Yan; (

    2001-01-01

    [1]Napoli, C., Lemieux, C., Jorgensen, R., Introduction of a chimeric chalone synthase gene into petunia results in reversible cosuppession of homologous genes in trans, The Plant Cell, 1990, 2: 279-289.[2]Van der Krol, A.R., Mur, L.A., Beld, M. M. et al., Flavonnoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression, The Plant Cell, 1990, 2: 291-299.[3]Manika, P.B., Bhadra, U., Birchler, J., Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase by White-Adh transgene is Polycomb dependent, Cell, 1997, 90: 479-498.[4]de Carvalho Niebel, F., Frendo, P., Van Montagu, M. et al., Post-transcriptional cosuppression of ?-1,3-glucanase transgene expression in homozygous plants, EMBO J., 1992, 11: 2595-2602.[5]Van Blokland, R., Van der Geest, N., Mol, J. N. M. et al., Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover, The Plant Cell, 1994, 6: 861-877.[6]Stam, M., Mol, J. N. M., Kooter, J. M., The silence of genes in transgenic plants, Annals of Bot., 1997, 79: 3-12.[7]Vaucheret, H., Beclin, C., Elmayan, T. et al., Transgene-induced gene silencing in plants, Plant J., 1998, 16(6): 651-659.[8]Shao, L., Li, Y., Yang, M. Z. et al., Transformation of Petunia hybrida with chalcone synthase A (chsA) resulting flower colour alteration and male sterility, Acta Botanica Sinica (in Chinese), 1996, 38(7): 517-524.[9]Koes, R. E., Spelt, C. E., Mol, J. N. M., The chalcone synthase multigene family of Petunia hybrida (V30): differential, light-regulated expression during flower development and UV light induction, Plant Mol. Biol., 1989, 12: 213-225.[10]Drews, G. N., Beals, T. P., Bul, A. Q. et al., Regional and cell-specific expression patterns during petal development, The Plant Cell, 1992, 4: 1383-1404.[11]Martin, C., Gerats, T., Control of pigment biosynthesis genes during petal development, The

  19. Cognitive Outcomes for Congenital Hypothyroid and Healthy Children: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Mahtab ORDOOEI

    2014-12-01

    , Mirzaei M, Motlagh M.E, Eslami Z, Afkhami-Ardekani M, et al. Prevalence of congenital hypothyroidism and transient increased levels of TSH in Yazd province. J Shahid Sadoughi Univ Med Sci 2008; 16:15-20. [Article in Persian]Hashemipour M, Hovsepian S, Kelishadi R, Iranpour R, Hadian R, Haghighi S, et al. Permanent and transient congenital hypothyroidism in Isfahan-Iran. J Med Screen 2009; 16:11-6.Dalili S, Rezvany SM, Dadashi A, Medghalchi A, Mohammadi H, Dalili H, et al. Congenital hypothyroidism: a review of the risk factors. Acta Med Iran 2012; 50:735-9.Zeinalzadeh AH, Talebi M. Neonatal screening for congenital hypothyroidism in East Azerbaijan, Iran: the first report. J Med Screen 2012; 19:123-6.Karamizadeh Z, Saneifard H, Amirhakimi G, Karamifar H, Alavi M. Evaluation of congenital hypothyroidism in Fars province, Iran. Iran J Pediatr 2012; 22:107-12.Bargagna S, Canepa G, Costagli C, Dinetti D, Marcheschi M, Millepiedi S, et al. Neuropsychological follow-up in early-treated congenital hypothyroidism: a problemoriented approach. Thyroid 2000; 10:243-9.van der Sluijs Veer L, Kempers MJ, Maurice-Stam H, Last BF, Vulsma T, Grootenhuis MA. Health- related quality of life and self-worth in 10-year old children with congenital hypothyroidism diagnosed by neonatal screening. Child Adolesc Psychiatry Ment Health 2012; 6:32.Soliman AT, Azzam S, Elawwa A, Saleem W. Linear growth and neurodevelopmental outcome of children with congenital hypothyroidism detected by neonatal screening: A controlled study. Indian J Endocrinol Metab 2012; 16:565-8.Bongers-Schokking JJ. Influence of timing and dose of thyroid hormone replacement on mental, psychomotor, and behavioral development in children with congenital hypothyroidism. J Pediatr 2005; 147:768-74.Wechsler, D. The Wechsler Preschool and Primary Scale of Intelligence - Manual. New York: psychological Corporation, 1967.Romero JB, Palacios GC, Gómez N, Silva A, Fabela JH. Intelligence quotient related with congenital hypothyroidism

  20. Depression and Anxiety in Iranian Mothers of Children with Epilepsy

    Directory of Open Access Journals (Sweden)

    Atefeh SOLTANIFAR

    2012-03-01

    JS, Lisonkova S. Periodprevalence of epilepsy in children in BC: a population-basedstudy. Can J Neurol Sci 2009 Jan;36(1:36-41.3. Otero S. Psychopathology and psychological adjustmentin children and adolescents with epilepsy. World J Pediatr2009 Feb;5(1:12-7.4. Rodenburg HR, Stams GJJM, Meijer AM, Aldenkamp AP,Dekovic´ M. Psychopathology in children with epilepsy:a metaanalysis. J Pediatr Psychol 2005 Sep;30(6:453-68.Epub 2005 Mar 3.5. Rodenburg R, Meijer AM, Dekovic M, AldenkampAP. Family factors and psychopathology in childrenwith epilepsy: a literature review. Epilepsy Behav 2005Jun;6(4:488-503.6. Lovejoy M, Graczyk PA, O_Hare E, Neuman G. Maternaldepression and parenting behavior: a meta-analytic reviewClin Psychol Rev 2000;20:561-92.7. Shore CP, Buelow JM, Austin JK, Johnson CS.Continuing psychosocial care needs in children with newonsetepilepsy and their parents. J Neurosci Nurs 2009Oct;41(5:244-50.8. Pianta RC, Lothman DJ. Predicting behavior problemsin children with epilepsy: child factors, disease factors,family stress, and child-mother interaction. Child Dev1994 Oct;65(5:1415-28.9. Dunn DW, Austin JK, Huster GA. Symptoms ofdepression in adolescents with epilepsy. J Am Acad ChildAdolesc Psychiatr 1999;38:1133-8.10. Shore CP, Austin JK, Huster GA, Dunn DW. Identifyingrisk factors for maternal depression in families ofadolescents with epilepsy. J Specialists Pediatr Nurs2002;7:71-80.11. Yongli, Cheng-Ye ji, Jiong Qin, Zhi-Xiang Zhang.Parental anxiety and quality of Life of epileptic children.Biomed Environ Sci 2008 Jun;21(3:228-32.12. Williams J, Steel C, Sharp GB, DelosReyes E, PhillipsT, Bates S, et al. Parental anxiety and quality of life inchildren with epilepsy. Epilepsy Behav 2003;4:483-6.13. Lv R, Wu L, Jin L, Lu Q, Wang M, Qu Y, Liu H. Depression,anxiety and quality of life in parents of children withepilepsy. Acta Neurol Scand 2009 Nov;120(5:335-41.14. Baki O, Erdogan A, Kantarci O, Akisik G, KayaalpL, Yalcinkaya C. Anxiety and depression in

  1. Psychiatric Aspects of Childhood Epilepsy

    Directory of Open Access Journals (Sweden)

    Raman Deep PATTANAYAK

    2012-06-01

    Full Text Available How to Cite this Article: Pattanayak RD, Sagar R. Psychiatric Aspects of Childhood Epilepsy. Iran J Child Neurol 2012;6(2:9-18.Childhood epilepsy is a chronic, recurrent disorder of unprovoked seizures. Theonset of epilepsy in childhood has significant implications for brain growth anddevelopment. Seizures may impair the ongoing neurodevelopmental processes and compromise the child’s intellectual and cognitive functioning, leading totremendous cognitive, behavioral and psychosocial consequences. Children with epilepsy are at increased risk for emotional and behavioral problems. In addition to the direct effects of epilepsy, there are multiple contributory factors including the underlying neurological abnormalities and adverse effects of medication. This review discusses the current understanding of various psychiatric aspects of childhood epilepsy, including the neuropsychological, behavioral and psychosocial concomitants of childhood epilepsy.References1. Shinnar S, Pellock JM. Update on the epidemiology and prognosis of pediatric epilepsy. J Child Neurol 2002;7 suppl 1:4-17.2. Murphy CC, Trevathan E, Yeargin-Allsopp M. Prevalence of epilepsy and epileptic seizures in 10-year-old children: results from the Metropolitan Atlanta Developmental Disabilities Study. Epilepsia 1995;36(9:866-72.3. Placencia M, Shorvon SD, Paredes V, Bimos C, Sander JW, Suarez J, et al. Epileptic seizures in an Andean region of Ecuador ncidence and prevalence and regional variation. Brain 1992;115:771-82.4. Henkin Y, Sadeh M, Kivity S, Shabtai E, KishonRabin L, Gadoth N. Cognitive function in idiopathic generalized epilepsy of childhood. Dev Med Child Neurol 2005;47:126-32.5. Rodenburg R, Stams GJ, Meijer AM, Aldenkamp AP, Dekovic M. Psychopathology in children with epilepsy: a meta-analysis. J Pediatr Psychol 2005;30(6:453-68.6. Caplan R, Siddarth P, Gurbani S, Ott D, Sankar R, Shields WD. Psychopathology and pediatric complex partial seizures: seizure