Acral peeling skin syndrome: a case of two brothers.

Science.gov (United States)

Wakade, Oojwala; Adams, Beth; Shwayder, Tor

2009-01-01

We report two brothers of Middle Eastern descent with consanguineous parents who present with numerous fragile, flaccid blisters on the hands and feet. In addition to spontaneous peeling, they can manually peel skin from acral areas without pain. The symptoms worsen with warm temperatures, excessive water exposure, and perspiration. Two biopsies from flaccid blisters on the feet were taken from the older brother, which revealed cleavage at the level of the stratum corneum. A diagnosis of acral peeling skin syndrome was made.

Correlation of WAIS IQ in 10 Pairs of Brothers.

Science.gov (United States)

Matarazzo, Joseph D.; And Others

1978-01-01

Pairs of brothers were individually examined with Wechsler Adult Intelligence Scale some 10 months apart by an experienced clinical psychologist unaware of the consanguineous relationship. Correlation of .42 for Full Scale IQ is consistent with median correlation reported by Erlenmeyer-Kimling and Jarvik in their 1963 literature review.…

75 FR 80669 - Wright Brothers Day, 2010

Science.gov (United States)

2010-12-22

... curious minds eager to transform and advance the world around them. Just as the Wright brothers... making great progress in ushering in a new commercial space industry that can help boost our economy...

75 FR 46864 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

Science.gov (United States)

2010-08-04

...-0225; Directorate Identifier 2009-NM-203-AD] RIN 2120-AA64 Airworthiness Directives; Short Brothers PLC... this proposed AD, contact Short Brothers PLC, Airworthiness, P.O. Box 241, Airport Road, Belfast, BT3... amend this proposed AD based on those comments. We will post all comments we receive, without change, to...

Cerebrotendinous xanthomatosis: report of two Brazilian brothers.

NARCIS (Netherlands)

Lange, M.C.; Zetola, V.F.; Teive, H.; Scola, R.H.; Trentin, A.P.; Zavala, J.A.; Pereira, E.R.; Raskin, S.; Werneck, L.C.; Sistermans, E.A.

2004-01-01

Cerebrotendinous xanthomatosis is a treatable rare autossomal recessive disease characterized by lipid storage secondary to a sterol 27-hydroxylase deficiency in the formation of cholic and chenodeoxycholic acids. We describe two Brazilian brothers with cognitive impairement and chronic diarrhea.

Mortality and health-related habits in 900 Finnish former elite athletes and their brothers.

Science.gov (United States)

Kontro, Titta Katariina; Sarna, Seppo; Kaprio, Jaakko; Kujala, Urho M

2018-01-01

There is conflicting evidence on the associations between participation in vigorous sports, health habits, familial factors and subsequent mortality. We investigated all-cause mortality and health-related behaviour among former elite athletes and their brothers. The mortality of Finnish male former elite athletes, who had represented Finland between 1920 and 1965 (n=900) and their age-matched brothers (n=900), was followed from the time when athlete started an elite athlete career until 31 December 2015. The age-adjusted HRs were calculated by a paired Cox proportional hazards model. In 2001, surviving participants (n=199 athletes and n=199 age-matched brothers) reported their self-rated health (SRH), physical activity, alcohol consumption and smoking habits in the questionnaire. During the total follow-up period, 1296 deaths (72% of the cohort) occurred. The age-adjusted HRs for all-cause mortality in former athletes was 0.75 (95% CI 0.65 to 0.87, Ppower sports athletes, and 77.5, 73.7 and 72.2 years for their age-matched brothers, respectively. In 2001, compared with their brothers, former athletes smoked less (P<0.001), were more physically active (P<0.05) and rated their health more often as very good (P<0.05). Former elite athletes are more physically active, smoke less, have better self-rated health and live longer than their brothers. Genetic differences between athletes and brothers, aerobic training for endurance elite sports and a healthier lifestyle may all contribute to reduced mortality. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Environmental behaviour of radioactivity from Chernobyl: Brothers Water study

International Nuclear Information System (INIS)

Bonnett, P.J.P.; Appleby, P.G.; Oldfield, F.; Haworth, E.Y.; Hilton, J.; Davison, W.

1992-01-01

A study has been carried out to examine the short term behaviour of Chernobyl derived radionuclides together with the longer term patterns of transport of weapons fallout derived 137 Cs first studied on the Brothers Water catchment in the English Lake District in the 1970's. Chernobyl derived radiocaesium is observable in the soils and lake sediments of the catchment. 210 Pb dating and diatom analysis were used to confirm that the lake sediments sampled were undisturbed. A simple box model is used to estimate radionuclide inventories in Brothers Water Lake sediments. Estimates derived using this model are reasonably consistent with estimates obtained from a variety of other sources. (author)

Living with a Brother Who Has an Autism Spectrum Disorder: A Sister's Perspective

Science.gov (United States)

Connell, Zara O.; Halloran, Maeve O.; Doody, Owen

2016-01-01

People with Autism Spectrum Disorder (ASD) are born into families and influence family functioning both positively and negatively. One of the most enduring relationships a person with ASD will have is their relationship with a brother or sister. Services for people with ASD should provide effective support to families, which include brothers,…

What Is That Song? : Aleksej Balabanov's Brother and Rock as Film Music in Russian Cinema

OpenAIRE

Österberg, Ira

2018-01-01

This dissertation examines the role of rock songs as film music in Russian cinema and how one important film, Aleksej Balabanov’s Brother (Brat, 1997), reshaped film music conventions in the 1990s. The study is divided into two sections: the first is a historical examination of more than twenty films made between the late 1920s and the early 1990s, the second focuses on Brother and its use of music. The research questions are 1) How is music used in Brother? 2) How were rock songs used in...

"I Loved My Brother Infinitely…"

OpenAIRE

Pavel Fokin

2014-01-01

Abstract Literary heritage of Mikhail Mikhailovich Dostoevsky(1820-1864) is not very abundant and appeals to experts only. His personality is of much more importance for national and world culture. He was a friend and soul mate of his genius brother (almost coeval). Their relations were an essential element of the biography and spiritual identity of Fyodor Dostoevsky. Mikhail was the first and for many years the only interlocutor of F.M. Dostoevsky. His role as an addressee in Fyodor Dosto...

76 FR 79019 - Wright Brothers Day, 2011

Science.gov (United States)

2011-12-20

... with earnings from their bicycle shop, gathering data on wing shape using a home-built wind tunnel and... the Wright brothers over a century ago. To reaffirm our role as the engine that drives science and..., must we press onward, exploring new frontiers of science, technology, and imagination in pursuit of a...

78 FR 76969 - Wright Brothers Day, 2013

Science.gov (United States)

2013-12-19

... champion STEM education in their communities. As we remember the Wright brothers, let us not forget another... results. That is why my Administration is dedicated to improving education in the vital fields of science... underrepresented groups, and through Race to the Top, we are raising standards and making STEM education a priority...

Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype

OpenAIRE

Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

2014-01-01

Background We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Methods Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. Results The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. T...

Freud on Brothers and Sisters: A Neglected Topic

Science.gov (United States)

Sherwin-White, Susan

2007-01-01

This paper explores Freud's developing thought on brothers and sisters, and their importance in his psychoanalytical writings and clinical work. Freud's work on sibling psychology has been seriously undervalued. This paper aims to give due recognition to Freud's work in this area. (Contains 1 note.)

The Wright Brothers and their First Flight

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 12. The Wright Brothers and their First Flight. O N Ramesh. Article-in-a-Box Volume 8 Issue 12 December 2003 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/008/12/0003-0004 ...

Homozygous PARK7 Mutation in Parkinson’s Disease: Case Report of Two Brothers

Directory of Open Access Journals (Sweden)

Hülya Apaydın

2008-06-01

Full Text Available OBJECTIVE: Genetic studies for Parkinson’s disease (PD which have been increased during last few years have shown that parkin (PARK2, DJ-1 (PARK7 and PINK-1 (PARK6 mutations can cause autosomal recessive early-onset parkinsonism. OBJECTIVE: The aim of this study was to investigate by genetic screening methods, the presence of possible genetic mutations in two siblings who have developed PD. METHODS: In these two brothers, PD started at the age of 48 with cervical dystonia and bradykinesia on the left arm, and 56 with tremor on the right hand, respectively. Although they had a favorable response to levodopa, they developed wearing-off phenomenon without dyskinesia on the 4th year. Besides dystonia, the younger brother experienced psychosis and impulse control disorder, as well. Family history revealed first degree consanguinity and the father had also a diagnosis of PD. PD progressed rather slowly in both, but unfortunately the older brother died due to lung cancer 10 years after the initial diagnosis of PD, while he was on the stage 2 of Hoehn-Yahr scale. The younger brother is still on our follow-up at the 7th year of his PD. Informed consent was obtained and blood samples were sent to the genetic department of Juntendo University in Japan for genetic analysis. Parkin gene mutation and DJ-1 gene mutation were analyzed on the PARK7 locus, by automated direct nucleotide sequencing and performed gene dosage assay using TaqMan real-time quantitive PCR. RESULTS: After excluding the parkin mutation the presence of PARK7 was detected in both siblings with haplotype analysis. DJ-1 gene mutation analysis responsible for PARK7, revealed a deletion on intron 1. CONCLUSION: A rarely encountered PARK7 mutation was identified in two brothers having slowly progressive PD and a favorable response to levodopa, one of whom also had psychotic symptoms. As in the presented cases, the genetic studies performed on early-onset PD patients with positive family

Inherited germline ATRX mutation in two brothers with ATR-X syndrome and osteosarcoma.

Science.gov (United States)

Ji, Jianling; Quindipan, Catherine; Parham, David; Shen, Lishuang; Ruble, David; Bootwalla, Moiz; Maglinte, Dennis T; Gai, Xiaowu; Saitta, Sulagna C; Biegel, Jaclyn A; Mascarenhas, Leo

2017-05-01

We report a family in which two brothers had an undiagnosed genetic disorder comprised of dysmorphic features, microcephaly, severe intellectual disability (non-verbal), mild anemia, and cryptorchidism. Both developed osteosarcoma. Trio exome sequencing (using blood samples from the younger brother and both parents) was performed and a nonsense NM_000489.4:c.7156C>T (p.Arg2386*) mutation in the ATRX gene was identified in the proband (hemizygous) and in the mother's peripheral blood DNA (heterozygous). The mother is healthy, does not exhibit any clinical manifestations of ATR-X syndrome and there was no family history of cancer. The same hemizygous pathogenic variant was confirmed in the affected older brother's skin tissue by subsequent Sanger sequencing. Chromosomal microarray studies of both brothers' osteosarcomas revealed complex copy number alterations consistent with the clinical diagnosis of osteosarcoma. Recently, somatic mutations in the ATRX gene have been observed as recurrent alterations in both osteosarcoma and brain tumors. However, it is unclear if there is any association between osteosarcoma and germline ATRX mutations, specifically in patients with constitutional ATR-X syndrome. This is the first report of osteosarcoma diagnosed in two males with ATR-X syndrome, suggesting a potential increased risk for cancer in patients with this disorder. © 2017 Wiley Periodicals, Inc.

The Perceptions and Experiences of Adolescent Siblings Who Have a Brother with Autism Spectrum Disorder

Science.gov (United States)

Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Reilly, Deirdre; Dowey, Alan

2012-01-01

Background: There is a dearth of research on the perspectives of adolescent siblings growing up with a brother or sister with an autism spectrum disorder (ASD). Method: Semistructured interviews were used to elicit the perceptions and experiences of 12 typically developing adolescents with a brother with an ASD. Interpretative phenomenological…

"Southern Pop Culture and the Literary Tradition in O Brother, Where Art Thou?"

DEFF Research Database (Denmark)

Bjerre, Thomas Ærvold

2009-01-01

  This essay discusses the Coen brothers movie O Brother, Where Art Thou? (2000). Rather than reading the movie as a modern retelling of The Odyssey, as most critics have done, it is read within a context of Southern literature and history. The essay points out and discusses the many references...

Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype.

Science.gov (United States)

Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

2014-09-19

We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. To the best of our knowledge, no similar phenotype has been reported previously. No abnormalities were detected by G-banding chromosome analysis or array comparative genomic hybridization. However, exome sequencing revealed novel mutations in the ATP-binding cassette, sub-family D member 1 (ABCD1) and Dachshund homolog 2 (DACH2) genes in both brothers. The ABCD1 mutation was a missense mutation c.1126G > C in exon 3 leading to a p.E376Q substitution. The DACH2 mutation was also a missense mutation c.1069A > T in exon 6, leading to a p.S357C substitution. The mother was an asymptomatic heterozygous carrier. Plasma levels of very-long-chain fatty acids were increased in both brothers, suggesting a diagnosis of adrenoleukodystrophy (ALD); however, their phenotype was not compatible with any reported forms of ALD. DACH2 plays an important role in the regulation of brain and limb development, suggesting that this mutation may be involved in the phenotype of the two brothers. The distinct phenotype demonstrated by these two brothers might represent a new form of ALD or a new syndrome. The combination of mutations in ABCD1 and DACH2 provides a plausible mechanism for this phenotype.

Brothers with constrictive pericarditis – A novel mutation in a rare disease

Directory of Open Access Journals (Sweden)

Devendra V. Patil

2016-09-01

Full Text Available Familial constrictive pericarditis is extremely rare. We report a case of two brothers both suffering constrictive pericarditis along with having multiple painless joint deformities. Genetic workup confirmed the clinical diagnosis of camptodactyly-arthropathy-coxa vara-pericarditis (CACP syndrome CACP syndrome and also revealed a rare mutation in the causative gene.

Laryngologist Leon Zamenhof--brother of Dr. Esperanto.

Science.gov (United States)

Wincewicz, Andrzej; Sulkowska, Mariola; Musiatowicz, Marcin; Sulkowski, Stanislaw

2009-06-01

To reconstruct the biography of the Polish otorhinolaryngologist Leon Zamenhof (1875-1934), a brother of Ludwik Zamenhof, who is famous for invention of the international language Esperanto. Biographical information was collected from pre-World War II resources. Zamenhof developed several important new forms of treatment to help the hearing impaired. Zamenhof was especially interested in the education of deaf children and the therapy necessary to facilitate their integration into society. His significant achievements were a phonetic method of therapy for the hearing impaired and an automatic device for ear insufflation that was considered indispensable in the management of pyorrhea. In addition, Zamenhof initiated various forms of social support among physicians within the medical community of Warsaw, Poland; made health care available to children with hearing impairments; and organized a Jewish school for deaf children. Zamenhof tried to change public attitudes toward deafness, working to promote the integration of the deaf into wider society. He also translated Polish literature into Esperanto. With similar aims to his brother Ludwik, Leon Zamenhof strived to enhance and broaden communication among people who could not hear and to persuade people to change their attitudes about deafness.

Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers.

Science.gov (United States)

Bandak, M; Jørgensen, N; Juul, A; Lauritsen, J; Kier, M G G; Mortensen, M S; Oturai, P S; Mortensen, J; Hojman, P; Helge, J W; Daugaard, G

2017-07-01

Testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to healthy controls. However, because of the fetal etiology of testicular cancer, familial unrelated healthy men might not be an optimal control group. The objective of this study was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39-50) vs. 46 (40-53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7-19). Serum levels of luteinizing hormone and follicle-stimulating hormone were elevated (p ≤ 0.001), while total testosterone, free testosterone, inhibin B and anti-Müllerian hormone were lower (p ≤ 0.001) in testicular cancer survivors than in their biological brothers. The prevalence of metabolic syndrome was similar and apart from HDL-cholesterol, which was lower in testicular cancer survivors (p = 0.01); there were no differences in the individual components of the metabolic syndrome between testicular cancer survivors and their brothers. In conclusion, gonadal function was impaired in testicular cancer survivors, while we did not detect any difference in the prevalence of metabolic syndrome between testicular cancer survivors and their biological brothers. © 2017 American

A new syndrome: multiple congenital abnormalities and mental retardation in two brothers.

Science.gov (United States)

Dundar, M; Ozdemir, S Y; Fryns, J P

2012-01-01

In this report we present two brothers with abnormal neurological development, hypotonia, short stature, pylorus stenosis, pectus excavatum, brachycephaly due to craniosynostosis, frontal bossing, depressed nasal bridge, high arched-wide palate, downslant palpebral fissures, low-set, large ears, thin upper lip and bilateral cryptorchidism. The brothers were born to a couple of second cousins and were the third and fourth pregnancies of the mother. The father, the mother and the eldest sibling were phenotypically and chromosomally normal. The clinical findings of the brothers were found to be similar. These clinical findings were compared with syndromes showing some of the symptoms, namely Apert, FG, Floating-Harbor, Shprintzen-Goldberg and Rett Syndromes. However, when the findings were detailed, we observed that they did not match completely any of the syndromes in a discernable way. The MECP2 gene mutation was analysed because of mental retardation, poor neurological evolution and large ears, but no mutation was found. So these cases are presented as a new syndrome with apparent autosomal recessive inheritance.

Propaganda in Warner Brothers World War II Cartoons.

Science.gov (United States)

Machowski, James Stanley; Brown, James William

To examine the role of the animated cartoon in propaganda associated with World War II, 194 of 262 cartoons produced for theatrical release by Warner Brothers, Inc., from 1939 to 1946 were analyzed. Propaganda content was determined by the number and nature of symbols used and the cartoon's "attitudes" toward these symbols. An analysis…

A Monument as a Text, or The Message of the Brothers Dostoevsky

Directory of Open Access Journals (Sweden)

Vladimir Zakharov

2014-12-01

Full Text Available The article considers the circumstances of the creation of a monument to the writer's mother Maria Fyodorovna Dostoevskaya. Mikhail Andreevich, father of the brothers Dostoevsky, asked Mikhail and Fyodor to compose the text for the monument. In March and April of 1837 the brothers worked out the idea and conception of the monument, wrote the text of the first and fourth epigraphs, chose evangelic verses and an epitaph of N.M. Karamzin. This was their first collective act of creative work embodied in stone. The monument is not only a symbol of love and sorrow for their mother’s death but also hope for her salvation and future resurrection. The brothers’ words and those chosen from the Gospel as well as the Karamzin’s ones have one more meaning. These convey a sense of beingness and an Easter idea of individual creative work. It is necessary to renew the tomb of Maria Fyodorovna Dostoevskaya and bring the monument back to Lazarevskoye cemetery in Moscow.

Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

DEFF Research Database (Denmark)

Bandak, M.; Jorgensen, N.; Juul, A.

2017-01-01

) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39–50) vs. 46 (40–53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7–19). Serum levels...... was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular...... cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III...

Testicular cancer in two brothers of a quadruplet: a case report and a review of literature.

Science.gov (United States)

Ulytė, Agnė; Ulys, Albertas; Sužiedėlis, Kęstutis; Patašius, Aušvydas; Smailytė, Giedrė

2017-01-01

Introduction. Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Case description. Both patients were diagnosed at 21 years of age and died within two years from the diagnosis despite treatment. The third symptomless brother did not have testicular pathology. We also review the risk factors associated with testicular cancer, and the proposed hypotheses how a multiple birth results in an increased risk. The most consistent risk factors for testicular cancer are cryptorchidism, prior history of testicular cancer, and a positive familial history. According to different studies, the risk of testicular cancer in twins is higher from 22% to 30%, compared to the general population. Conclusions. To our knowledge, we have presented the first case of testicular teratoblastoma in brothers of a quadruplet.

Do brothers and sisters of siblings with intelectual disability need the support of social work?

OpenAIRE

Cardová, Michaela

2007-01-01

This thesis explores the experience and support needs of siblings with a brother or sister with intellectual disability. Through review of what is a quite limited literature and from original qualitative research, involving interviews with siblings, the author examines their social reality, focusing especially on their relationships with their disabled brother or sister and with the wider society. Particular attention is given to identifying to what extent the siblings' lives are influenced b...

Discussing the Life of the Others: Doing Ethnography in the Brazilian Big Brother Fan Community

Directory of Open Access Journals (Sweden)

Bruno Campanella

2009-05-01

Full Text Available The aim of this paper is to present some of the initial results of ethnographic research conducted in early 2008 with the online fan community of the Brazilian Big Brother (BBB. After a brief introduction to some of the challenges faced by ethnographic work on television audiences in the last couple of decades, the current piece will explore some of the main characteristics constituting this new social space. Beyond the gossiping, and the more immediate talks about behaviors and game strategies of the Big Brother housemates, these forums sometimes trigger exchanges about Brazilian society at large, and the role of television broadcasting in general. Nonetheless, a closer inspection reveals how the debates found in the community are themselves permeated by the participants' struggle for status.

ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing

OpenAIRE

Moncini, S.; Bedeschi, M.F.; Castronovo, P.; Crippa, M.; Calvello, M.; Garghentino, R.R.; Scuvera, G.; Finelli, P.; Venturin, M.

2013-01-01

In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allow...

Brothers and reduction of the birth weight of later-born siblings

DEFF Research Database (Denmark)

Nielsen, Henriette Svarre; Mortensen, Laust; Nygaard, Ulrikka

2008-01-01

It has been speculated whether maternal immune responses against male-specific minor histocompatibility (H-Y) antigens affect pregnancies negatively. This study explores, on a population level, whether previous births of boys compared with girls are associated with a decrease in birth weight...... of later-born siblings. The population was identified in the Danish Birth Registry and consisted of all Danish women who gave birth to their first-born singleton from 1980 to 1998. The women were followed until 2004, and their subsequent births were recorded. A total of 545,839 second- to fourth......-born children were identified. The authors used linear regression to analyze the association between sex of preceding children and birth weight of subsequent siblings. Brothers compared with sisters reduced the birth weight of later-born siblings. One or two brothers, respectively, reduced the mean birth weight...

20 CFR 410.340 - Determination of relationship; parent, brother, or sister.

Science.gov (United States)

2010-04-01

... domiciled (see § 410.392) at the time of his death would find, under the law they would apply in determining..., brother, or sister. Where, under such law, the individual does not bear the relationship to the miner of...

Living with a brother or sister with epilepsy: siblings' experiences.

Science.gov (United States)

Hames, Annette; Appleton, Richard

2009-12-01

There is conflicting evidence about the impact of disability upon siblings, and very little research on the siblings of children with epilepsy. There is some evidence that siblings who have less accurate information exhibit more distress. The aim of this study was to assess siblings' response to having a brother or sister with epilepsy and to begin to develop information for them. Parents of children attending paediatric neurology outpatient departments were invited to participate in a pilot study. Parents who consented to take part were asked if they had previously received information for siblings. Parents and siblings participated in a semi-structured interview and siblings were also invited to submit a personal account of living with a brother or sister who had epilepsy. Twenty-five families with a child with epilepsy aged 2.5-15 years initially agreed to take part. None of the families stated that they had ever seen or received any information specifically for siblings. Fourteen siblings from the 25 families, aged 8-25 years, provided a personal account of what it was like living with a brother or sister with epilepsy. Siblings' accounts included both negative and positive feelings, and specifically feelings of care and love for their sibling. This initial study suggests that siblings of children with epilepsy have many positive but also early negative feelings. The results are limited by the size of the study, the fact that most siblings were older sisters, and the mean time since diagnosis was 6 years. Finally, it is hoped that the personal accounts collected in this study will be published for the benefit of other siblings of children with epilepsy.

Qualitative comparative analysis of Grimm brothers' and Manica Koman's fairy tales, based on the structuralist literary theory of Vladimir J. Propp

OpenAIRE

Ložar, Ana

2012-01-01

The present BA thesis, titled A Qualitative Comparative Analysis of Grimm Brothers' and Manica Koman's Fairy Tales, Based on the Structuralist Literary Theory of Vladimir J. Propp, consists of two parts. The first one presents the biography and work of the Grimm brothers, and the biography and work of Manica Koman, a Slovene folktale writer. Biography and work facts about the former were mainly found in Hermann Gerstner's detailed biography of the Brothers Grimm, Die Brűder Grimm: Ei...

Adult Sibling Relationships with Brothers and Sisters with Severe Disabilities

Science.gov (United States)

Rossetti, Zach; Hall, Sarah

2015-01-01

The purpose of this qualitative study was to examine perceptions of adult sibling relationships with a brother or sister with severe disabilities and the contexts affecting the relationships. Adult siblings without disabilities (N = 79) from 19 to 72 years of age completed an online survey with four open-ended questions about their relationship…

ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing.

Science.gov (United States)

Moncini, S; Bedeschi, M F; Castronovo, P; Crippa, M; Calvello, M; Garghentino, R R; Scuvera, G; Finelli, P; Venturin, M

2013-12-01

In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allowed the identification of the ATRX c.109C>T (p.R37X) mutation in both the affected brothers. Sanger sequencing confirmed the presence of the mutation in the brothers and showed that the mother is a healthy carrier. Mutations in the ATRX gene cause the X-linked alpha thalassemia/mental retardation (ATR-X) syndrome (MIM #301040), a severe clinical condition usually associated with profound ID, facial dysmorphism and alpha thalassemia. However, the syndrome is clinically heterogeneous and some mutations, including the c.109C>T, are associated with a broad phenotypic spectrum, with patients displaying a less severe phenotype with only mild-moderate ID. In the case presented here, exome sequencing provided an effective strategy to achieve the molecular diagnosis of ATR-X syndrome, which otherwise would have been difficult to consider due to the mild non-specific phenotype and the absence of a family history with typical severe cases.

Commissioner for Inland Revenue V Lever Brothers and Unilever Ltd

African Journals Online (AJOL)

Lever Brothers, the South African tax case that formed the basis of this research, was concerned with determining the source of interest income. In its time, this was one of the landmark cases and established tax principles that were valid for 54 years, until superseded by changes to legislation. The research presented a ...

Learning to Fly: The Wright Brothers' Adventure. A Guide for Educators and Students with Activities in Aeronautics

Science.gov (United States)

Storm, R.; Benson, T.; Galica, C.; McCredie, P.

2003-01-01

This guide was produced by the NASA Glenn Research Center Office of Educational Programs in Cleveland, OH, and the NASA Aerospace Educational Coordinating Committee. It includes activity modules for students, including the history of the Wright Brothers and their family in Dayton, Ohio and flight experimentation in Kitty Hawk, North Carolina. Student activities such as building models of the Wright Brothers glider and writing press releases of the initial flight are included.

Commissioner for Inland Revenue v Lever Brothers and Unilever Ltd

African Journals Online (AJOL)

kirstam

21Key words: Lever Brothers and Unilever; South African income tax; source of income; interest; the “practical man”; the .... facilities, and he housed his employees in a model village of well-built homes on the factory site. ... be cancelled and any excess of the value of the shares over the debt would be adjusted by a money.

Constraints on the source of Cu in a submarine magmatic-hydrothermal system, Brothers volcano, Kermadec island arc

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Keith, Manuel; Haase, Karsten M.; Klemd, Reiner; Smith, Daniel J.; Schwarz-Schampera, Ulrich; Bach, Wolfgang

2018-05-01

Most magmatic-hydrothermal Cu deposits are genetically linked to arc magmas. However, most continental or oceanic arc magmas are barren, and hence new methods have to be developed to distinguish between barren and mineralised arc systems. Source composition, melting conditions, the timing of S saturation and an initial chalcophile element-enrichment represent important parameters that control the potential of a subduction setting to host an economically valuable deposit. Brothers volcano in the Kermadec island arc is one of the best-studied examples of arc-related submarine magmatic-hydrothermal activity. This study, for the first time, compares the chemical and mineralogical composition of the Brothers seafloor massive sulphides and the associated dacitic to rhyolitic lavas that host the hydrothermal system. Incompatible trace element ratios, such as La/Sm and Ce/Pb, indicate that the basaltic melts from L'Esperance volcano may represent a parental analogue to the more evolved Brothers lavas. Copper-rich magmatic sulphides (Cu > 2 wt%) identified in fresh volcanic glass and phenocryst phases, such as clinopyroxene, plagioclase and Fe-Ti oxide suggest that the surrounding lavas that host the Brothers hydrothermal system represent a potential Cu source for the sulphide ores at the seafloor. Thermodynamic calculations reveal that the Brothers melts reached volatile saturation during their evolution. Melt inclusion data and the occurrence of sulphides along vesicle margins indicate that an exsolving volatile phase extracted Cu from the silicate melt and probably contributed it to the overlying hydrothermal system. Hence, the formation of the Cu-rich seafloor massive sulphides (up to 35.6 wt%) is probably due to the contribution of Cu from a bimodal source including wall rock leaching and magmatic degassing, in a mineralisation style that is hybrid between Cyprus-type volcanic-hosted massive sulphide and subaerial epithermal-porphyry deposits.

"Brothers and Sisters": A Novel Way to Teach Human Resources Management.

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Bumpus, Minnette

2000-01-01

The novel "Brothers and Sisters" by Bebe Moore Campbell was used in a management course to explore human resource management issues, concepts, and theories. The course included prereading and postreading surveys, lecture, book review, and examination. Most of the students (92%) felt the novel was an appropriate way to meet course…

Isolated Penile Torsion in Brothers: A Case Report

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Metin Gunduz

2012-04-01

Full Text Available Penile torsion can be congenital and associated with hypospadias and chordee, or can be acquired after circumcision. The incidence of isolated neonatal penile torsion was 1.7 to 27% in the literature. The majority were between 10 and deg; and 20 and deg;. Generally, torsion was to the left in cases. The techniques for correction of penile torsion described in the literature are penile de-gloving and reattaching of skin, resection of Buck's fascia incising the base of the penis and removing angular ellipses of corporeal tissue with subsequent plication of tunica, and dorsal dartos flap rotation in severe cases. In conclusion, penile torsion may be familial. Therefore, brothers should be examined carefully. The degloving and realignment technique is successful in isolated penile torsion. [Arch Clin Exp Surg 2012; 1(2.000: 122-124

Cancer risk in fathers and brothers of testicular cancer patients in Denmark. A population-based study.

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Westergaard, T; Olsen, J H; Frisch, M; Kroman, N; Nielsen, J W; Melbye, M

1996-05-29

There are several reports of familial testicular cancer in the literature but few systematic attempts have been made to estimate the risk of testicular cancer in first-degree relatives of patients with this neoplasm, and the risk remains to be fully assessed in population-based studies. By means of data from the Danish Cancer Registry, we identified all testicular cancer patients (index cases) born and diagnosed during 1950-1993 in Denmark. Their fathers were identified from national registries, as were the brothers of a subcohort of these patients. Familial cancer occurrence was determined through linkage with the cancer registry and compared with the cancer incidence in the general male population in Denmark. The ratio of observed to expected cancers generated the measure used for the relative risk. Fathers of 2,113 index cases with testicular cancer experienced an almost 2-fold risk of developing testicular cancer themselves (RR = 1.96; 95% CI: 1.01-3.43). Overall, the fathers had a decreased relative cancer risk (RR = 0.84; 95% CI: 0.74-0.95) with a significantly decreased risk of cancers of the lung and digestive organs. Brothers of a subcohort of 702 index cases showed a markedly increased risk of testicular cancer (RR = 12.3; 95% CI: 3.3-3 1.5). In conclusion, we documented a significantly increased familial risk of testicular cancer which was relatively more pronounced between brothers than between fathers and sons. These findings support the possible involvement of a genetic component in the aetiology of testicular cancer, but also leave room for a hypothesized influence of in-utero exposures, such as specific maternal hormone levels, that might be shared by brothers.

KAKO PREDŠKOLSKA DJECA VIDE "BIG BROTHER" SHOW?

OpenAIRE

Janković, Andrea; Sindik, Joško; Jaman, Kamea

2007-01-01

Cilj istraživanja bio je ispitivanje nekih karakteristika gledanosti Big Brother show-a kod djece predškolske dobi, razloga gledanja te emisije, s aspekta preferiranih sadržaja emisije te ličnosti (kandidata) koje preferiraju djeca. Ispitan je prigodni uzorak djece srednje i starije vrtićke dobi iz 3 dječja vrtića iz Zagreba (Dječjeg vrtića Grigora Viteza i Dječjeg vrtića "Maksimir" i "Trnoružica", N = 142). Utvrđene su čestine razloga preferencije pojedinih sudionika show–a te pojedinih s...

Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

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Nadia Skauli

2016-11-01

Full Text Available Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3, characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val in two brothers with several of the typical features of MCAHS3, but in addition, pyramidal tract neurological signs. Notably, they are the first patients with MCAHS3 without skeletal, cardiac, or genitourinary anomalies. PIGT encodes a crucial subunit of the glycosylphosphatidylinositol (GPI transamidase complex, which catalyzes the attachment of proteins to GPI-anchors, attaching the proteins to the cell membrane. In vitro studies in cells from the two brothers showed reduced levels of GPI-anchors and GPI-anchored proteins on the cell surface, supporting the pathogenicity of the novel PIGT variant.

76 FR 1985 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

Science.gov (United States)

2011-01-12

... Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes AGENCY: Federal Aviation Administration (FAA..., at an average labor rate of $85 per work hour. Required parts cost about $10 per product. Based on.... The average labor rate is $85 per work-hour. Based on these figures, we estimate the cost of the AD on...

Exercise electrocardiogram testing in two brothers with different outcome – a case study exercise testing in master cyclists

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Rüst CA

2013-06-01

Full Text Available Christoph Alexander Rüst,1 Beat Knechtle,1,2 Thomas Rosemann11Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, SwitzerlandAbstract: The cases of two brothers training and competing as master cyclists and both preparing for a cycling tour are presented. The older brother aged 66 years went first to the primary care physician and presented with an asymptomatic depression in the exercise stress test of the ST segment in V5 and V6 during recovery after complete exhaustion. Coronary angiography revealed a multi vessel coronary artery disease and he underwent bypass surgery. One year later, he successfully completed his planned cycling tour of ~600 km in seven stages and covering ~12,000 m of total ascent. The younger brother aged 59 years went a few months later to the primary care physician and also performed asymptomatic exercise stress testing without changes in the ST segments. Unfortunately, 2 months later he suffered a cardiac arrest during his cycling tour and survived following immediate successful cardiopulmonary resuscitation on the road by his cycling colleagues. Immediate invasive coronary arteriography showed a complete stenosis of the trunk of arteria coronaria sinistra (left coronary artery, a 40%–50% stenosis of ramus circumflexus, and a 20% stenosis of arteria coronaria dextra (right coronary artery. The left coronary artery was dilated and he continued cycling 2 months later. In both brothers, familial hypercholesterolemia was the main cardiovascular risk factor for the multi vessel coronary artery disease. A negative exercise electrocardiogram in siblings with an increased risk for coronary artery disease seemed not to exclude an advanced multi vessel coronary artery disease. In master athletes with asymptomatic exercise electrocardiogram but a positive family history, further examinations should be performed in order to detect

Biological versus nonbiological older brothers and men’s sexual orientation

OpenAIRE

Bogaert, Anthony F.

2006-01-01

The most consistent biodemographic correlate of sexual orientation in men is the number of older brothers (fraternal birth order). The mechanism underlying this effect remains unknown. In this article, I provide a direct test pitting prenatal against postnatal (e.g., social/rearing) mechanisms. Four samples of homosexual and heterosexual men (total n = 944), including one sample of men raised in nonbiological and blended families (e.g., raised with half- or step-siblings or as adoptees) were ...

Blood Brothers: Albert and Allen Hughes in the Belly of the Hollywood Beast.

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Gates, Henry Louis, Jr.

1994-01-01

Recounts an interview with the Hughes brothers, who are twin black men who produced the film "Menace 2 Society," which is a film about urban delinquency and crime among black adolescents. Their comments include thoughts on racism, media stereotyping, being black in America, and their experiences with Hollywood. (GLR)

Power in Play: A Foucauldian Reading of A.O. Soyinka’s The Trials of Brother Jero

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Mahboobeh Davoodifar

2015-12-01

Full Text Available This work utilizes Foucault’s articulations on the power strategies of our contemporary society. To him the subject’s constitution is never a purely passive effect of power on the subject but requires the subject’s own activity. This necessitates the existence of a dynamic, mutually affecting relationship, implying that one can be both dominated and dominate at different times and in different contexts. This article aims to analyze the Nigerian Noble Laureate, Wole Soyinka’s play The Trials of Brother Jero, a prophetical play that criticizes the ills of society through its satirical depiction, in the light of Foucault’s conceptualizations on power. To do this, the article first clarifies Foucault’s mature understanding of the operation of power and then attempts to provide an in-depth analysis of the structure of the power regime and its relations in the play, tactics of domination, and more importantly, the characters’ relations to the existing system of power. The study of the language and the dialogue of the main characters, Brother Jero, Amope, Chume and a Member of Federation House not only exposes the sources of operating power relations, but it also highlights the characters’ desire for power and the way it flows and slips from one character to another. The findings of the paper reveals that power is not concentrated on merely one character or institution within the play, rather, it circulates, and through the active resistance of the dominated characters, it constantly engenders new meanings within the structure of the play. In The Trials of Brother Jero, different characters have the desire to use power against each other and the resistance of each of them indicates that power is neither possessive nor repressive. Keywords: Michel Foucault, Power, Pastoral Power, Resistance, Wole Soyinka

Extreme intrafamilial variability of Saudi brothers with primary hyperoxaluria type 1

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Alfadhel M

2012-08-01

Full Text Available Majid Alfadhel,1 Khalid A Alhasan,2 Mohammed Alotaibi,3 Khalid Al Fakeeh41Division of Genetics, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 2Division of Nephrology Department of Pediatrics, King Saud University King Khalid University Hospital, Riyadh, Saudi Arabia; 3Department of Radiology, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 4Division of Nephrology, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi ArabiaBackground: Primary hyperoxaluria type 1 (PH1 is characterized by progressive renal insufficiency culminating in end-stage renal disease, and a wide range of clinical features related to systemic oxalosis in different organs. It is caused by autosomal recessive deficiency of alanine:glyoxylate aminotransferase due to a defect in AGXT gene.Case report: Two brothers (one 6 months old; the other 2 years old presented with acute renal failure and urinary tract infection respectively. PH1 was confirmed by high urinary oxalate level, demonstration of oxalate crystals in bone biopsy, and pathogenic homozygous known AGXT gene mutation. Despite the same genetic background, same sex, and shared environment, the outcome of the two siblings differs widely. While one of them died earlier with end-stage renal disease and multiorgan failure caused by systemic oxalosis, the older brother is pyridoxine responsive with normal development and renal function.Conclusion: Clinicians should be aware of extreme intrafamilial variability of PH1 and international registries are needed to characterize the genotype-phenotype correlation in such disorder.Keywords: primary hyperoxaluria, oxalosis, PH1, intrafamilial variability

Reluctant Romantics – On the fairy tale poetics of the Brothers Grimm and their relationship to German Romanticism

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Isabel dos Santos

2014-12-01

Full Text Available The legacy of the Brothers Grimm continues to fascinate readers and researchers alike. The 200-year anniversary of the first publication of their fairy tales sparked a renewed interest in the life, work and times of the brothers. Fascinated by the past, by the political present and by the literary future of Romanticism, the Brothers Grimm stayed together in an unusual working union. They established what was to become German philology and published many invaluable works on language and history, myths and folk tales. This article will focus on the brothers’ place in German Romanticism through their contribution of fairy tales. The period was marked by political and philosophical thought that emphasised authentic experienced and the spiritual unity of art, science and philosophy. There was a strong call for national emancipation. Literature was required to embody this unity through an established national literature founded on German folk traditions. The Grimms seemed to have heeded that call. But a careful study reveals that their intentions were motivated less by the literary movement than by their own strong convictions which they upheld even at the cost of compromising the authenticity they claimed to uphold in their poetics. The many controversies regarding the origins, collection and editing of the fairy tales is inextricably linked to the brothers’ difficult relationship with the Romantic Movement. Two hundred years later, this article seeks to give an appraisal of the Brothers’ motivation for their poetics and of the research conducted thus far.

Catholic nursing sisters and brothers and racial justice in mid-20th-century America.

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Wall, Barbra Mann

2009-01-01

This historical article considers nursing's work for social justice in the 1960s civil rights movement through the lens of religious sisters and brothers who advocated for racial equality. The article examines Catholic nurses' work with African Americans in the mid-20th century that took place amid the prevailing social conditions of poverty and racial disempowerment, conditions that were linked to serious health consequences. Historical methodology is used within the framework of "bearing witness," a term often used in relation to the civil rights movement and one the sisters themselves employed. Two situations involving nurses in the mid-20th century are examined: the civil rights movement in Selma, Alabama, and the actions for racial justice in Chicago, Illinois. The thoughts and actions of Catholic sister and brother nurses in the mid-20th century are chronicled, including those few sister nurses who stepped outside their ordinary roles in an attempt to change an unjust system entirely.

A Thousand Lights [and] A Thousand Lights: Teacher and Parent Guide. Brothers Series.

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Benton, Hope

This book for children (ages 8 to 14) and the accompanying teacher/parent guide present the story of two brothers, one of whom has a severe hearing impairment, who climb up Mt. Fuji in Japan. Information on the disability is presented subtly and incidentally to encourage the reader to relate more personally and foster a deeper level of acceptance…

Brothers and Sisters of Adults with Mental Retardation: Gendered Nature of the Sibling Relationship.

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Orsmond, Gael I.; Seltzer, Marsha Mailick

2000-01-01

Differences and similarities between 245 brothers and sisters of adults with mental retardation in the sibling relationship were examined. Sisters scored higher in the caregiving, companionship, and positive affect aspects of the sibling relationship. Sibling involvement increased over time, but was dependent upon changes in maternal health.…

A sterile sperm caste protects brother fertile sperm from female-mediated death in Drosophila pseudoobscura

DEFF Research Database (Denmark)

Holman, Luke; Snook, Rhonda R

2008-01-01

antispermicidal mechanisms have been definitively identified. One such adaptation may be the enigmatic infertile sperm morphs or "parasperm" produced by many species, which have been hypothesized to protect their fertile brother "eusperm" from spermicide [2, 3]. Here, we show that female Drosophila pseudoobscura...

[Sense of coherence and ways of coping in the relationship with brother or sister in healthy siblings of mentally ill persons].

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Osuchowska-Kościjańska, Anna; Charzyńska, Katarzyna; Chadzyńska, Małgorzata; Drozdzyńska, Anna; Kasperek-Zimowska, Beata; Bednarek, Agata; Sawicka, Maryla

2014-01-01

The aim of the present study was to investigate sense of coherence in healthy siblings of persons suffering from schizophrenia as well as their ways of coping in the relationship with ill brother or sister. 40 healthy brothers and sisters of persons with ICD- 10 diagnosis of F20 to F29 participated in the present study. Orientation to Life Scale (SOC- 29) was used to assess sense of coherence and Ways of Coping with Stress questionnaire (SRSS) was used to examine stress coping strategies. Mean global score of siblings of persons with schizophrenia was 111 points. Subjects used coping strategies focused on problem significantly more often than those focused on emotions. Therapeutic work with healthy siblings should focus on strengthening sense of personal competence, development of personal resources and different ways of coping with stress, investigation of emotions that healthy siblings experience in the relationship with ill brother or sister as well as supporting the process of accepting changes in the relationship with the ill sibling.

Career choices of migrant artists between Amsterdam and Antwerp. The Van Nieulandt brothers

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Eric Jan Sluijter

2015-12-01

Full Text Available This essay examines the career choices of the brothers Guilliam II and Adriaen II van Nieulandt. Both were born in Antwerp but moved with their parents to Amsterdam at a young age. Guilliam returned to Antwerp to make his career, while Adriaen became embedded in Amsterdam’s artistic community. All members of their family – in Antwerp, Amsterdam and Rome – remained in close contact with each other, though changes in the religious and political culture left their mark on their professional decisions. Their choices did not yield artistic innovations but conservative styles and subjects based on shared Netherlandish traditions with a strong international flavour.

My Brother as "Problem": Neoliberal Governmentality and Interventions for Black Young Men and Boys

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Dumas, Michael J.

2016-01-01

In this article, the author argues that the Obama Administration's My Brother's Keeper (MBK) initiative serves as an exemplar of neoliberal governmentality, in which Black young men and boys are constructed as essentially damaged, as problems in need of a technocratic public--private solution. More than simply an ideological imposition from above…

[Undifferentiated soft tissue tumor with rhabdoid phenotype (extra-renal rhabdoid tumor). Report of a congenital case associated with medulloblastoma in a brother].

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Costes, V; Medioni, D; Durand, L; Sarran, N; Marguerite, G; Baldet, P

1997-03-01

We report a case of congenital cervical rhabdoid tumor with association of a medulloblastoma in a brother. The immunohistochemical features of this tumor are compatible with a neuroectodermal differentiation (MIC 2+, Leu 7+). Extrarenal rhabdoid tumors share a common morphology but do not represent a single entity with only one histogenesis. Most of them are now considered to be of neuroectodermal origin. In our case, the association with a medulloblastoma in a brother seems to confirm this concept.

Palmo-Plantar hyperkeratosis, intellectual disability, and spastic paraplegia in two maternal half brothers: further evidence for an X-linked inheritance.

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Isidor, Bertrand; Lefebvre, Tiphaine; Barbarot, Sébastien; Perrier, Julie; Mercier, Sandra; Péréon, Yann; Le Caignec, Cédric; David, Albert

2013-06-01

In 1983, Fitzsimmons et al. reported four brothers with an unrecognized disorder characterized by intellectual disability, spastic paraplegia, and palmo-plantar hyperkeratosis (OMIM 309500). In this report, we describe a family in which two males, maternal half-brothers, had learning disabilities. Both patients also showed spasticity in the lower limbs and palmo-plantar hyperkeratosis. The mother of the affected boys had learning difficulties but did not show any dermatological symptoms. This report confirms that the association of features reported by Fitzsimmons et al. is a distinct entity and further suggests an X-linked mode of inheritance. Copyright © 2013 Wiley Periodicals, Inc.

Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.

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Aydin, Halil Ibrahim

2018-01-15

Creatine transporter deficiency (CTD) is a treatable, X-linked, inborn error of metabolism. Two brothers with autism spectrum disorder were diagnosed with CTD at the ages of 17 and 12 years. Both were found to have a previously reported hemizygous p.408delF (c.1216_1218delTTC) deletion mutation. Both patients were given creatine monohydrate, L-arginine, L-glycine and S-adenosylmethionine, which partially improved the behavioral problems. Serum creatinine levels, creatine peak at brain MR spectroscopy or creatine/creatinine ratio in urine should be evaluated to identify CTD in children with autistic behavior and language disorders.

On Brothers and Sisters: South Asian and Japanese Idea Systems and their Consequences

OpenAIRE

Lyon, Stephen M.

2017-01-01

The role expectations of cross siblings varies across culture. Such expectations, while not rigidly prescribing actual behaviors nevertheless influences relations between brothers and sisters in observable ways. In South Asia, a cultural rhetoric of sororal sacrifice and support coupled with fraternal protection are commonplace. While such noble sibling roles are regularly transgressed they remain powerful idioms of the relationship and transgressions require appropriate cultural justificatio...

Mentoring in Schools: An Impact Study of Big Brothers Big Sisters School-Based Mentoring

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Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; McMaken, Jennifer

2011-01-01

This random assignment impact study of Big Brothers Big Sisters School-Based Mentoring involved 1,139 9- to 16-year-old students in 10 cities nationwide. Youth were randomly assigned to either a treatment group (receiving mentoring) or a control group (receiving no mentoring) and were followed for 1.5 school years. At the end of the first school…

20 CFR 222.40 - When determinations of relationship are made for parent, grandchild, brother or sister.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When determinations of relationship are made... RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent..., brother or sister. (a) Parent. The claimant's relationship as a parent of the employee is determined when...

Persistence of Müllerian derivatives and intestinal lymphangiectasis in two newborn brothers: confirmation of the Urioste syndrome

NARCIS (Netherlands)

Bellini, C.; Bonioli, E.; Josso, N.; Belville, C.; Mazzella, M.; Costabel, S.; Sementa, A. R.; Marino, C. E.; Tomà, P.; Hennekam, R. C.; Serra, G.

2001-01-01

We describe two newborn brothers with a pattern of malformation characterized by the persistence of Müllerian duct derivatives, intestinal lymphangiectasia, hypertrophied alveolar ridges, and early death. Postmortem examination showed the presence of a rudimentary uterus, fallopian tubes, the upper

The Role of Digital Literacy Practices on Refugee Resettlement: The Case of Three Karen Brothers

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Gilhooly, Daniel; Lee, Eunbae

2014-01-01

This study explores the social and cultural uses of digital literacies by adolescent immigrants to cope with their new lives in the United States. This case study focuses on three adolescent ethnic Karen brothers. Two years of participant observations in their home and Karen community, accompanied by formal and informal interviews, served as the…

Magnetic resonance in Pelizaeus Merzbacher disease: findings in three brothers presenting the connatal variant

International Nuclear Information System (INIS)

Saez, J.; Perez, F.; Fuster, M.J.; Marti, L.

1997-01-01

Pelizaeus Merzbacher disease is a rare hereditary disorder of the white matter that is characterized by nystagmic eye movements, head shaking and severe psychomotor retardation. We report the MR findings in three brothers presenting the connatal variant of the disease, which is characterized by a diffuse increase in signal intensity on T2-weighted sequences, involving the white matter of the CNS. (Author) 10 refs

Improving Emotion Regulation and Sibling Relationship Quality: The More Fun with Sisters and Brothers Program

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Kennedy, Denise E.; Kramer, Laurie

2008-01-01

We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…

Germline activating MTOR mutation arising through gonadal mosaicism in two brothers with megalencephaly and neurodevelopmental abnormalities.

Science.gov (United States)

Mroske, Cameron; Rasmussen, Kristen; Shinde, Deepali N; Huether, Robert; Powis, Zoe; Lu, Hsiao-Mei; Baxter, Ruth M; McPherson, Elizabeth; Tang, Sha

2015-11-05

In humans, Mammalian Target of Rapamycin (MTOR) encodes a 300 kDa serine/ threonine protein kinase that is ubiquitously expressed, particularly at high levels in brain. MTOR functions as an integrator of multiple cellular processes, and in so doing either directly or indirectly regulates the phosphorylation of at least 800 proteins. While somatic MTOR mutations have been recognized in tumors for many years, and more recently in hemimegalencephaly, germline MTOR mutations have rarely been described. We report the successful application of family-trio Diagnostic Exome Sequencing (DES) to identify the underlying molecular etiology in two brothers with multiple neurological and developmental lesions, and for whom previous testing was non-diagnostic. The affected brothers, who were 6 and 23 years of age at the time of DES, presented symptoms including but not limited to mild Autism Spectrum Disorder (ASD), megalencephaly, gross motor skill delay, cryptorchidism and bilateral iris coloboma. Importantly, we determined that each affected brother harbored the MTOR missense alteration p.E1799K (c.5395G>A). This exact variant has been previously identified in multiple independent human somatic cancer samples and has been shown to result in increased MTOR activation. Further, recent independent reports describe two unrelated families in whom p.E1799K co-segregated with megalencephaly and intellectual disability (ID); in both cases, p.E1799K was shown to have originated due to germline mosaicism. In the case of the family reported herein, the absence of p.E1799K in genomic DNA extracted from the blood of either parent suggests that this alteration most likely arose due to gonadal mosaicism. Further, the p.E1799K variant exerts its effect by a gain-of-function (GOF), autosomal dominant mechanism. Herein, we describe the use of DES to uncover an activating MTOR missense alteration of gonadal mosaic origin that is likely to be the causative mutation in two brothers who present

When Your "Problem" Becomes Mine: Adult Female Siblings' Perspectives of Having a Brother with a Disability

Science.gov (United States)

Pompeo, Michelle N.

2009-01-01

This study is a retrospective look at adult female siblings' perspectives of their childhoods and present identities based on having a brother with a disability. This paper focuses on siblings' experiences within educational and public domains, and how such experiences have shaped their personalities and career choices. Qualitative findings were…

Family Configuration and Achievement: Effects of Birth Order and Family Size in a Sample of Brothers.

Science.gov (United States)

Olneck, Michael R.; Bills, David B.

1979-01-01

Birth order effects in brothers were found to derive from difference in family size. Effects for family size were found even with socioeconomic background controlled. Nor were family size effects explained by parental ability. The importance of unmeasured preferences or economic resources that vary across families was suggested. (Author/RD)

Ter um irmão especial: convivendo com a Síndrome de Down Having a special brother/sister: living together with the Down Syndrome

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Eucia Beatriz Lopes Petean

2005-12-01

Full Text Available O presente estudo teve por objetivos conhecer como é a relação entre irmãos mais velhos de pessoas com diagnóstico de Síndrome de Down (SD; que informações e sentimentos possuem sobre o diagnóstico; se houve ou não modificações na dinâmica familiar e em suas próprias vidas. Foram entrevistadas 11 pessoas, de ambos os sexos, com idade superior a dez anos, sendo, cada uma, o irmão mais velho de criança com diagnóstico de SD, sendo realizada análise quantitativa de dados da amostra e análise quantitativa-interpretativa e qualitativa para os dados da entrevista. Os dados mostram que a maioria dos sujeitos (90,9% sabe o nome da Síndrome e foram informados pela mãe logo após o nascimento do irmão, seis deles consideram que reagiram normalmente à notícia. Quanto às responsabilidades adquiridas, a maioria, 90,9%, são responsáveis pelas atividades de vida diária; 27,27% deles consideram que houve acréscimo de responsabilidade em suas vidas em decorrência do nascimento do irmão com SD. Em relação ao sentimento que apresentam por terem um irmão especial, 54,54% consideram como positivo, ou seja, disseram que também sentem-se especiais. Na falta (morte dos pais, a metade dos participantes informa que eles serão os responsáveis legais deste irmão. Pode-se concluir que o nascimento de um irmão com SD tem conseqüências na rotina de vida dos irmãos mais velhos, trazendo modificações e responsabilidades para eles. Entretanto, parece ter um efeito menos dirigido para a desestrutura psicológica, sendo poucas as manifestações de sentimentos extremos, ficando apenas no nível da tristeza, quando são expressos.The present study intended to know about the relation among older brothers/sisters of people with a diagnosis of Down Syndrome (DS, regarding to information and feelings they have about this diagnosis, and if changes have occurred within family dynamics and their own lives. Eleven people were interviewed, from

Gabriel García Márquez's «Eréndira» and the Brothers Grimm

Directory of Open Access Journals (Sweden)

Joel Hancock

1978-08-01

Full Text Available García Márquez's long story «La increíble y triste historia de la Cándida Eréndira y de su abuela desalmada» is studied in the light of the structures and themes of the fairy tale, particularly of the type collected by the Grimm brothers. Dimensions of special interest are the organizational framework of the narrative, the portrayal of characters, and certain motifs, all of which are strongly reminiscent of Grimm's Fairy Tales . These elements are examined as representative of those morphologies which Vladimir Propp delineates for the genre of the fairy tale in his Morphology of the Folktale .

Metabolic syndrome, hypertension, and hyperlipidemia in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis.

Science.gov (United States)

Yilmaz, Bulent; Vellanki, Priyathama; Ata, Baris; Yildiz, Bulent Okan

2018-02-01

To provide an evidence-based assessment of metabolic syndrome, hypertension, and hyperlipidemia in first-degree relatives of women with polycystic ovary syndrome (PCOS). Systematic review and meta-analysis. Not applicable. Mothers, fathers, sisters, and brothers of women with and without PCOS. An electronic-based search with the use of PubMed from 1960 to June 2015 and cross-checked references of relevant articles. Metabolic syndrome, hypertension and dyslipidemia, and surrogate markers, including systolic blood pressure (BP), diastolic BP, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Fourteen of 3,346 studies were included in the meta-analysis. Prevalence of the following was significantly increased in relatives of women with PCOS: metabolic syndrome (risk ratio [RR] 1.78 [95% confidence interval 1.37, 2.30] in mothers, 1.43 [1.12, 1.81] in fathers, and 1.50 [1.12, 2.00] in sisters), hypertension (RR 1.93 [1.58, 2.35] in fathers, 2.92 [1.92, 4.45] in sisters), and dyslipidemia (RR 3.86 [2.54, 5.85] in brothers and 1.29 [1.11, 1.50] in fathers). Moreover, systolic BP (mothers, sisters, and brothers), total cholesterol (mothers and sisters), low-density lipoprotein cholesterol (sisters), and triglycerides (mothers and sisters) were significantly higher in first-degree relatives of PCOS probands than in controls. Our results show evidence of clustering for metabolic syndrome, hypertension, and dyslipidemia in mothers, fathers, sisters, and brothers of women with PCOS. PROSPERO 2016 CRD42016048557. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

The first mutation in CNGA2 in two brothers with anosmia

DEFF Research Database (Denmark)

Karstensen, H G; Mang, Y; Fark, T

2015-01-01

that the cyclic nucleotide-gated channel subunit CNGA2, expressed in the olfactory epithelium has a crucial role in olfactory signal transduction. We have identified a novel X-linked stop mutation in CNGA2 (c.634C>T, p.R212*) in two brothers with ICA using exome sequencing. No additional mutations in CNGA2 were...... identified in a cohort of 31 non-related ICA individuals. Magnetic resonance brain imaging revealed diminished olfactory bulbs and flattened olfactory sulci. This is the first report of a mutation in the cyclic nucleotide-gated gene CNGA2 and supports the critical role of this gene in human olfaction....

The paths of salvation and eternal condemnation: The presence of the allegory in the History of the Elected Pilgrim and his Brother Precito (1682, de Alexandre de Gusmão

Directory of Open Access Journals (Sweden)

José Adriano Filho

2015-04-01

Full Text Available The repercussions of the echoes of the Council of Trent (1546-1563, the Counter Reform movement, and the repercussions they had on the artistic production in the Catholic world. The pedagogical-didactic intents behind its composition are grounded on the belief that art could be an effective tool for reconverting of the faithful and for indoctrination in the values of the Catholic faith. Considering that, this paper aims at presenting the way allegory became an important tool for the interpretation and construction of religious discourse, as we can see in the History of the Elected Pilgrim and his Brother Precito. The book is an allegorical narrative that presents the history of two pilgrim brothers born in Egypt from where they set out with the intention of making a fortune (one brother goes to Jerusalem, and the  other one goes to Babylon. In this way, the book presents continuity with the medieval pattern that highlights the journey, especially the path for salvation. The readiness of allegory to transmit abstract concepts through concrete visualizations allied to a form of indirect expression made it a powerful, didactic, apologetic, and entertaining tool for that time.

Brothers with hypospadias, vertebral segmentation defects, and intellectual disability: new syndrome?

Science.gov (United States)

Phadke, Shubha R; Ranganath, Prajnya; Boggula, Vijay Raju; Gupta, Divya; Phadke, Rajendra V; Sloman, Melissa; Turnpenny, Peter D

2012-12-01

We report on two brothers (born to nonconsanguineous parents) with short stature, hypospadias, scoliosis, vertebral segmentation defects of "spondylocostal dysostosis" type, and intellectual disability. Results of cytogenetic and molecular genetic tests performed, including routine karyotype, MLPA (multiplex ligation-dependent probe amplification) for common microdeletions and subtelomeric copy number variants, microarray-CGH analysis, and sequencing of four Notch signaling pathway genes (DLL3, MESP2, LFNG, and HES7), were all normal. We present a comparison of the condition in the two boys with known syndromes and suggest that they may represent a hitherto unreported syndrome, most likely following autosomal recessive inheritance, though X-linked inheritance is not excluded. Copyright © 2012 Wiley Periodicals, Inc.

Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families.

Science.gov (United States)

Arteaga-Vázquez, Jazmín; López-Hernández, María A; Svyryd, Yevgeniya; Mutchinick, Osvaldo M

2015-12-01

Androgenetic alopecia (AGA) or common baldness is the most prevalent form of hair loss in males. Familial predisposition has been recognized, and heritability estimated in monozygotic twins suggests an important genetic predisposition. Several studies indicate that the numbers of CAG/GGC repeats in exon 1 of the androgen receptor gene (AR) maybe associated with AGA susceptibility. To investigate a possible correlation between AR CAG/GGC haplotypes and the presence or not of alopecia in sibships with two or more brothers among them at least one of them has AGA. Thirty-two trios including an alopecic man, one brother alopecic or not, and their mother were enrolled. Sanger sequencing of the exon 1 of the AR gene was conducted to ascertain the number of CAG/GGC repeats in each individual. Heterozygous mother for the CAG/GGC haplotypes was an inclusion criterion to analyze the segregation haplotype patterns in the family. Concordance for the number of repeats and AGA among brothers was evaluated using kappa coefficient and the probability of association in the presence of genetic linkage between CAG and GGC repeats and AGA estimated by means of the family-based association test (FBAT). The median for the CAG and GGC repeats in the AR is similar to that reported in other populations. The CAG/GGC haplotypes were less polymorphic than that reported in other studies, especially due to the GGC number of repeats found. Kappa coefficient resulted in a concordance of 37.3% (IC 95%, 5.0-69.0%) for the AGA phenotype and identical CAG/GGC haplotypes. There was no evidence of linkage disequilibrium. Our results do not confirm a possible correlation or linkage disequilibrium between the CAG/GGC haplotypes of the AR gene and androgenetic alopecia in Mexican brothers. © 2015 Wiley Periodicals, Inc.

A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections

Directory of Open Access Journals (Sweden)

Xu Xiu

2012-08-01

Full Text Available Abstract Background Autistic spectrum disorders (ASDs are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Case presentation Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 – 153,589,577 from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. Conclusions To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

Energy Technology Data Exchange (ETDEWEB)

Oliveira, G.; Boechat, M.I.; Fereira, M.A.

1983-07-01

A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

OpenAIRE

Skauli, Nadia; Wallace, Sean; Chiang, Samuel C. C.; Bar?y, Tuva; Holmgren, Asbj?rn; Stray-Pedersen, Asbj?rg; Bryceson, Yenan T.; Str?mme, Petter; Frengen, Eirik; Misceo, Doriana

2016-01-01

Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3), characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val) in two brothers w...

Lipid myopathy associated with renal tubular acidosis and spastic diplegia in two brothers.

Science.gov (United States)

Tung, Y C; Tsau, Y K; Chu, L W; Young, C; Shen, Y Z

2001-07-01

Lipid myopathy is a group of disorders involving mitochondrial fatty acid oxidation. We describe two brothers, 3 years 8 months old and 2 years 9 months old, respectively, with progressive spastic diplegia, developmental delay, failure to thrive, and chronic metabolic acidosis who had lipid myopathy and renal tubular acidosis. Brain magnetic resonance imaging revealed demyelinating changes in the periventricular white matter, which was compatible with spastic diplegia. These symptoms may be related to errors in fatty acid metabolism. Cerebral palsy had been misdiagnosed in both of these patients at another hospital. Therefore, for patients with late-onset and progressive spastic diplegia, detailed investigations for underlying diseases are warranted.

Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

International Nuclear Information System (INIS)

Oliveira, G.; Boechat, M.I.; Fereira, M.A.

1983-01-01

A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process. (orig.)

HASIL RANCANG BANGUN SISTEM ERP DENGAN SDLC MODEL WATERFALL: STUDI KASUS SISTEM INVENTORI PT PAN BROTHERS, TBK.

OpenAIRE

Harijanto Pangestu; Hendra Alianto; Santo F. Wijaya

2012-01-01

Competition in the business world effects the use of information technology. To achieve competitive advantage in the global competition, PT Pan Brothers, Tbk. should establish an integrated information system based on ERP (Enterprise Resource Planning). With the ERP system, information will be accurate and up-todate to support strategic decision making. It takes conscientious planning in building the ERP system. Management information systems development projects have a very important role. O...

The Montgolfier Brothers and the Invention of Aviation

Science.gov (United States)

Moore, Charles B.

The first hot air balloon ascension over Paris in September 1783 has been described so many times that it and its passengers—the sheep, the rooster, and the duck—have joined Benjamin Franklin and his kite in the folklore of our culture. Not so well known is the earlier history of ballooning; that the brothers Montgolfier had demonstrated their hot air balloons repeatedly for several months prior to the ascent over Paris; or that the physicist Charles, urged onward and financed by an enthusiast, Barthélemy Faujas de Saint-Fond, launched successfully the first fabric balloon filled with hydrogen over Paris more than 3 weeks prior to the memorable ascent of the sheep, and rooster, and the duck.For all of its well-documented detail, the book is readable and enjoyable. It is a well-written but complex book in which Professor Gillispie develops a number of subjects to recreate the era in perspective. The origins and the disposition of the Montgolfiers, the industry of the period, the idea of capturing heated air are all reported in detail. The attempts to obtain government funding and the promotional activities in Paris were forerunners of the modern techniques for obtaining support of research activities.

Adolescent Siblings of Individuals with and without Intellectual and Developmental Disabilities: Self-Reported Empathy and Feelings about Their Brothers and Sisters

Science.gov (United States)

Shivers, Carolyn M.; Dykens, Elisabeth M.

2017-01-01

Siblings of brothers or sisters with intellectual and developmental disabilities (IDD) are important but understudied family members. As many previous studies have relied on parent report of sibling outcomes, the use of sibling self-report is an important addition to the research. This study assessed the feelings of adolescent siblings toward…

Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

DEFF Research Database (Denmark)

Vorwerk, P; Christoffersen, C T; Müller, J

1999-01-01

The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...... either of the two mutated receptors lacked basal or stimulated IR beta-subunit autophosphorylation. A third brother who inherited both normal alleles has an normal muscle phenotype and insulin sensitivity, suggesting a direct linkage of these IR mutations with the CFTDM phenotype....

Changes in Siblings Over Time After the Death of a Brother or Sister From Cancer.

Science.gov (United States)

Akard, Terrah Foster; Skeens, Micah A; Fortney, Christine A; Dietrich, Mary S; Gilmer, Mary Jo; Vannatta, Kathryn; Barrera, Maru; Davies, Betty; Wray, Sarah; Gerhardt, Cynthia A

2018-02-27

Limited research has examined the impact of a child's death from cancer on siblings. Even less is known about how these siblings change over time. This study compared changes in siblings 1 (T1) and 2 (T2) years after the death of a brother or sister from cancer based on bereaved parent and sibling interviews. Participants across 3 institutions represented 27 families and included bereaved mothers (n = 21), fathers (n = 15), and siblings (n = 26) ranging from 8 to 17 years old. Participants completed semistructured interviews. Content analysis identified emerging themes and included frequency counts of participant responses. McNemar tests examined differences in the frequency of responses between T1 and T2 data. Participants reported similar types of changes in bereaved siblings at both time points, including changes in sibling relationships, life perspectives, their personal lives, and school performance. A new theme of "openness" emerged at T2. Frequencies of responses differed according to mother, father, or sibling informant. Overall, participants less frequently reported changes at T2 versus T1. Compared with findings in the first year, participants reported greater sibling maturity at follow-up. Overall changes in bereaved siblings continued over 2 years with less frequency over time, with the exception of increases in maturity and openness. Providers can educate parents regarding the impact of death of a brother or sister over time. Nurses can foster open communication in surviving grieving siblings and parents as potential protective factors in families going through their grief.

"I like that He Always Shows Who He Is": The Perceptions and Experiences of Siblings with a Brother with Autism Spectrum Disorder

Science.gov (United States)

Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Dowey, Alan; Reilly, Deirdre

2009-01-01

Semi-structured interviews were used to explore the perceptions and experiences of eight typically developing siblings in middle childhood who had a brother with autism spectrum disorder (ASD). The interviews were analysed using interpretative phenomenological analysis (IPA). The analysis yielded five main themes: (i) siblings' perceptions of the…

A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections.

Science.gov (United States)

Xu, Xiu; Xu, Qiong; Zhang, Ying; Zhang, Xiaodi; Cheng, Tianlin; Wu, Bingbing; Ding, Yanhua; Lu, Ping; Zheng, Jingjing; Zhang, Min; Qiu, Zilong; Yu, Xiang

2012-08-21

Autistic spectrum disorders (ASDs) are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 - 153,589,577) from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

Traits of ADHD and autism in girls with a twin brother

DEFF Research Database (Denmark)

Attermann, Jørn; Obel, Carsten; Bilenberg, Niels

2012-01-01

It has been hypothesized that prenatal exposure to testosterone may be associated with traits of attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder (ASD). We conducted a population-based study of dizygotic female twins to elucidate this hypothesis, assuming that the sex...... of the co-twin influences the level of prenatal exposure to testosterone. We invited parents of 24,552 3- to 15-year-old twins to answer questionnaires on traits of ADHD and ASD. We analysed the data using a proportional odds model with sex of the co-twin as an instrumental variable for prenatal exposure...... to testosterone of female twins. We received responses for 6,339 girls from dizygotic twin pairs. Odds ratios for male versus female co-twin were 0.71 (95 % confidence interval 0.61-0.81) for ADHD traits and 0.74 (0.66-0.83) for ASD traits, indicating that a twin brother reduces traits of ADHD and ASD in females...

[The brothers of Jumiege--the peripheral nervous system in early French mythology].

Science.gov (United States)

Brean, Are

2002-03-20

This article reviews the process of discovery of the nervous system from Pythagoras (570-500 BC) to Galen (130-201 AD). After Galen, no anatomical studies were performed before the renaissance. According to a legend, probably produced for political reasons, two brothers, sons of the French king Clovis II, revolted against their father and were sentenced to loose their physical powers by having the nerves of their arms and legs cut. They were then set adrift on the river Seine, stranding at the Jumiège monastery. The earliest written version of this legend stems from the fourteenth century; it was probably a part of the local French mythology. This indicates that the existence of the peripheral nervous system, and therefore also in part the knowledge contained in the early anatomical works, quite early may have been more or less known outside academic circles.

Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

Directory of Open Access Journals (Sweden)

Verhoeven WMA

2012-04-01

Full Text Available Willem MA Verhoeven1,2, Jos IM Egger1,3,4, Marjolein H Willemsen5, Gert JM de Leijer6, Tjitske Kleefstra51Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray, 2Erasmus University Medical Centre, Department of Psychiatry, Rotterdam, 3Donders Centre for Cognition, Radboud University Nijmegen, Nijmegen, 4Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, 5Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, 6Dichterbij, Institutes for Intellectual Disabilities, Gennep, The NetherlandsAbstract: The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances, communication deficits, and motor perseverations. Data on psychological dysfunctions are so far not available. Previous studies have suggested that the loss of one copy of the gene SH3 and multiple ankyrin repeat domains 3 (SHANK3 is related to the neurobehavioral phenotype. Additional genes proximal to SHANK3 are also likely to play a role in the phenotype of patients with larger deletions. The present paper describes two adult brothers with an identical 2.15 Mb 22qter (22q13.32q13.33 deletion, of whom the youngest was referred for evaluation of recurrent mood changes. In both patients, magnetic resonance imaging of the brain showed hypoplasia of the vermis cerebelli. Extensive clinical examinations led to a final diagnosis of atypical bipolar disorder, of which symptoms fully remitted during treatment with a mood stabilizer. In the older brother, a similar psychopathological picture appeared to be present, although less severe and with a later onset. It is concluded that the behavioral phenotype of the 22q13.3 deletion syndrome comprises absent or delayed speech and perseverations

Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

NARCIS (Netherlands)

Eeten, E. van; Faber, H.T.; Kunst, D.

2017-01-01

We report the case of two young brothers with Epstein-Barr virus (EBV) otomastoiditis complicated by a facial nerve paralysis. The boys, aged 7 months (patient A) and 2 years and 8 months (patient B), were diagnosed with a facial nerve paralysis House-Brackmann (HB) grade IV (A) and V (B). After

[1896: How nascent radiotherapy gathered Roentgen, Pasteur and the Lumière brothers].

Science.gov (United States)

Foray, N

2016-12-01

On the 4th July, 1896, in his medical office of Les Échelles (Savoie, France), Victor Despeignes performed the very first radiotherapy against cancer, documented by indisputable proofs. However, the intellectual and practical approach that leads to this first radiotherapy may appear unexpected to date. Indeed, it is likely that the treatment that Despeignes applied to his neighbour, who did not suffer from stomach cancer, was born with the indirect support of the Lumière brothers, on the basis of a biological theory (the parasitory theory of cancer) that is irrelevant today, with an experimental protocol based on experiments performed on tuberculosis et in a bifractionated model linked by the constraints of a district medical doctor. Copyright © 2016 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

Sustained virologic response following HCV eradication in two brothers with X-linked agammaglobulinaemia.

LENUS (Irish Health Repository)

Houlihan, Diarmaid D

2009-08-21

X-linked agammaglobulinaemia (XLA) is a humoral immunodeficiency syndrome characterized from childhood by the absence of circulating B lymphocytes, absent or reduced levels of serum immunoglobulin and recurrent bacterial infections. For many affected patients, regular treatment with immunoglobulin is life saving. Hepatitis C viral (HCV) infection acquired through contaminated blood products is widely described in this patient cohort. The natural history of HCV infection in patients with XLA tends to follow a more rapid and aggressive course compared to immunocompetent individuals. Furthermore, standard anti-viral therapy appears to be less efficacious in this patient cohort. Here we report the cases of two brothers with XLA who contracted HCV through contaminated blood products. They were treated with a six month course of Interferon alpha-2b and Ribavirin. We report a sustained virologic response five years after completing treatment.

Challenging stereotypes? The older woman in the TV series Brothers & Sisters.

Science.gov (United States)

Oró-Piqueras, Maricel

2014-12-01

The TV series, Brothers & Sisters, broadcast from 2006 to 2011 by ABC (USA) and a year later by Channel 4 (UK) with quite high audience rates, starts when the patriarchal figure, William Walker, dies of a heart attack and two female figures around their sixties come center stage: his wife, Nora Walker, and his long-term lover, Holly Harper. Once the patriarchal figure disappears, the female characters regain visibility by entering the labor market and starting relationships with other men. In that sense, both protagonists experience aging as a time in which they are increasingly freed from social and family constraints. However, their roles as nurturers keep on bringing them back to the domestic space in which they are safe from being involved in uncomfortable and unsuitable situations. Drawing on previous studies on the representation of the older woman in fictional media, this article intends to discern to what extent stereotypes related to the older woman are challenged through the two main protagonists of a contemporary TV series. Copyright © 2014 Elsevier Inc. All rights reserved.

Cognitive ability in young adulthood and risk of dementia in a cohort of Danish men, brothers, and twins

DEFF Research Database (Denmark)

Osler, Merete; Christensen, Gunhild T; Garde, Ellen

2017-01-01

INTRODUCTION: We examined the association between cognitive ability in young adulthood and dementia in Danish men, brothers, and male twins. METHODS: In total, 666,986 men born between 1939 and 1959 were identified for dementia diagnosis in national registries from 1969 to 2016. The association.......03-1.13]). The intrabrother and twin analyses (taking shared family factors into account) showed attenuated risk estimates but with wide CIs. DISCUSSION: Low early-life cognitive ability increases the risk of dementia before the age of 78 years. The association is partly explained by shared family factors....

Non-marfan idiopathic medionecrosis (cystic medial necrosis) presenting with multiple visceral artery aneurysms and diffuse connective tissue fragility: Two brothers

International Nuclear Information System (INIS)

Kubota, Jun; Tsunemura, Mami; Amano, Shigeko; Tokizawa, Shigemi; Oowada, Susumu; Shinkai, Hiroko; Maehara, Yasunobu; Endo, Keigo

1997-01-01

Two brothers with multiple visceral artery aneurysms or dilatations and diffuse connective tissue fragility who did not have clinical features of Marfan syndrome are reported. One presented with retroperitoneal hemorrhage during angiography, and idiopathic medionecrosis was proved by resection of the aneurysms. These cases belong to the heterogeneous group of Marfan syndrome. The angiographical features (multiple dilation of visceral arteries) suggests fragility of connective tissue and is predictive of hazards during and after a catheterization and operation

Non-marfan idiopathic medionecrosis (cystic medial necrosis) presenting with multiple visceral artery aneurysms and diffuse connective tissue fragility: Two brothers

Energy Technology Data Exchange (ETDEWEB)

Kubota, Jun [Gunma University School of Medicine, Department of Nuclear Medicine (Japan); Tsunemura, Mami [Gunma University School of Medicine, Department of Diagnostic Radiology (Japan); Amano, Shigeko [Gunma University School of Medicine, Department of Nuclear Medicine (Japan); Tokizawa, Shigemi [Gunma University School of Medicine, Department of Hygiene and Virology (Japan); Oowada, Susumu [Gunma University School of Medicine, Department of Second Surgery (Japan); Shinkai, Hiroko [Gunma Health Foundation (Japan); Maehara, Yasunobu [Gunma University School of Medicine, Department of Diagnostic Radiology (Japan); Endo, Keigo [Gunma University School of Medicine, Department of Nuclear Medicine (Japan)

1997-05-15

Two brothers with multiple visceral artery aneurysms or dilatations and diffuse connective tissue fragility who did not have clinical features of Marfan syndrome are reported. One presented with retroperitoneal hemorrhage during angiography, and idiopathic medionecrosis was proved by resection of the aneurysms. These cases belong to the heterogeneous group of Marfan syndrome. The angiographical features (multiple dilation of visceral arteries) suggests fragility of connective tissue and is predictive of hazards during and after a catheterization and operation.

« Nous sommes tous frères ». Les valeurs des Elephants de Brother, club de baseball professionnel à Taiwan “We are all Brothers”. The Values of Brother Elephants, professional baseball club in Taiwan

Directory of Open Access Journals (Sweden)

Jérôme Soldani

2013-06-01

Full Text Available À Taiwan, où le baseball est considéré comme le « sport national », les équipes professionnelles sont la propriété de grandes firmes locales et ne sont pas formellement attachées à une municipalité. Ce sont elles-mêmes de petites entreprises qui proposent, en archétype de société, un mode de fonctionnement interne qui repose sur des valeurs autour desquelles se fédèrent leurs supporters. Basée sur une enquête ethnographique de douze mois, notamment au sein de la formation professionnelle des Elephants de Brother, cette contribution montrera comment celle-ci se donne à voir comme une entreprise structurée autour de valeurs morales entendues comme « traditionnelles » et dont les joueurs de l’équipe sont érigés en parangons. Le modèle d’une famille unie et strictement hiérarchisée est mis en exergue par les propriétaires du club et son iconographie. Mais ces représentations se heurtent à la réalité de la pratique quotidienne et aux affaires de corruption qui sapent régulièrement l’image de la ligue professionnelle taiwanaise.In Taiwan, where baseball is considered as the national sport, professional teams are owned by large local firms and are not formally attached to a municipality. They are themselves small companies offering an archetypal society, whose mode of internal operations are based on values around which to unite their fans. Based on an ethnographic study of twelve months, particularly among the professional team of Brother Elephants, this contribution will show how it is to be seen as an enterprise structured around moral values understood as traditional and whose players are established as paragons. The model of a united family and strictly hierarchical is highlighted by the owners of the club and its iconography. But these representations are faced with the reality of daily practice and corruption that regularly undermine the image of the Taiwanese professional league.

Sounding the Bromance: The Chopstick Brothers' 'Little Apple' music video, genre, gender and the search for meaning in Chinese popular music

OpenAIRE

Stock, Jonathan P. J.

2016-01-01

This article analyses the music video of ‘Little Apple’ by Wang Taili and Xiao Yang, also known as the Chopstick Brothers, one of China’s most successful productions in 2014, and one that exemplifies certain emerging trends in Chinese popular music more generally. The music video draws on K-pop models but also on Western inspirations (biblical, historical and contemporary) and has proven hard to reduce to a single, definitive narrative or interpretation. The analysis proceeds by introducing t...

"My Brother Likes Meeting New People, but Don't Ask Him Any Direct Questions": Involving Adults with Autism plus Learning Disability in a Qualitative Research Project

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Tozer, Rosemary; Atkin, Karl; Wenham, Aniela

2014-01-01

Adult siblings of people with autism and a learning disability have hitherto been largely overlooked by research, policy and practice in the UK. As part of a qualitative study focussing on adult siblings, we met twelve people with autism plus severe learning disability with their brother or sister. Individually tailored resources were used to make…

On the Use of Sibiling Data to Estimate the Effects of Family Background, Cognitive Skills, and Schooling: Results from the Kalamazoo Brothers Study. Discussion Papers 374-76.

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Olneck, Michael R.

Sibling data drawn from the Kalamazoo Brothers sample are used in this report to assess the adequacy of conventional sociological variables for measuring family background, to estimate the overall effects of family background on test scores, education, occupational status, and earning, and to control family background when estimating the effects…

[Fragile X syndrome and white matter abnormalities: Case study of two brothers].

Science.gov (United States)

Wallach, E; Bieth, E; Sevely, A; Cances, C

2017-03-01

Fragile X syndrome is the most usual cause of hereditary intellectual deficiency. Typical symptoms combine intellectual deficiency, social anxiety, intense emotional vigilance, and a characteristic facial dysmorphy. This is subsequent to a complete mutation of the FMR1 gene, considering a semidominant transmission linked to the unstable X. The expansion of the CGG triplet greater than 200 units combined with a high methylation pattern lead to a transcriptional silence of the FMR1 gene, and the protein product, the FMRP, is not synthesized. This protein is involved in synaptic plasticity. Brain MRI can show an increased volume of the caudate nucleus and hippocampus, combined with hypoplasia of the cerebellar vermis. Fragile X Associated Tremor Ataxia Syndrome (FXTAS) syndrome is a neurodegenerative disorder occurring in carriers of the premutation in FMR1. Brain MRI shows an increased T2 signal in the middle cerebellar peduncles. This syndrome is linked to a premutation in the FMR1 gene. We report here the case of two brothers presenting a typical fragile X symptomatology. Brain MRI showed hyperintensities of the middle cerebellar peduncles. Such MRI findings support the assumption of a genetic mosaicism. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Sixty Days Remaining, Forty Years of CERN, Two Brothers, One Exclusive Interview

CERN Multimedia

2001-01-01

Twins Marcel and Daniel Genolin while sharing memories of their CERN experiences, point out just how much smaller the Meyrin site once was. In a place such as CERN where the physical sciences are in many ways the essence of our daily lives and where technological advancement is an everyday occurrence, it is easy to lose track of the days, months, and even years. But last week twin brothers, Daniel and Marcel Genolin, hired in the early sixties and getting ready to end their eventful forty year CERN experiences, made it clear that the winds of time bluster past us whether we are aware or not. 'CERN was very small when we started' says Marcel, who has worked in transport during his entire time here. A lot has changed. 'When I got here there were no phones in peoples' houses' he recalls,'when there were problems in the control room with the PS (Proton Synchrotron) they used to get a megaphone and tell us {the transport service} to go and get the necessary physicists from their homes in the area. We had to lo...

[Psychotherapy with a boy with depression following the death of his 2 brothers].

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Zollinger, R

1997-12-01

The author describes the psychotherapy of about 2 1/2 years duration of a 14-year old boy. This psychodynamically oriented psychotherapy dealt with the aftermath of two disasters in his family: The accidental deaths of two older brothers five and four years ago. These events had a lasting effect on the family which negatively interfered with the achievement of developmental tasks in adolescence in the patient. He had erected massive defenses against his own wishes and became withdrawn and depressed. The main issues dealt with in therapy were: (a) The boys fear to step out of his position as the families "child" in consideration of his grieving mother. (b) The boy's difficulty to tolerate and integrate aggressive fantasies and feelings because of his guilt feelings and fear of another loss due to these fantasies and feelings. The working through of conflictual issues in psychotherapy enabled the boy to gain awareness regarding his own needs and wishes, and to find ways to fulfill them. Subsequently, he succeeded in making an adequate professional choice and to go into training for it.

A novel AVPR2 splice site mutation leads to partial X-linked nephrogenic diabetes insipidus in two brothers.

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Schernthaner-Reiter, Marie Helene; Adams, David; Trivellin, Giampaolo; Ramnitz, Mary Scott; Raygada, Margarita; Golas, Gretchen; Faucz, Fabio R; Nilsson, Ola; Nella, Aikaterini A; Dileepan, Kavitha; Lodish, Maya; Lee, Paul; Tifft, Cynthia; Markello, Thomas; Gahl, William; Stratakis, Constantine A

2016-05-01

X-linked nephrogenic diabetes insipidus (NDI, OMIM#304800) is caused by mutations in the arginine vasopressin (AVP, OMIM*192340) receptor type 2 (AVPR2, OMIM*300538) gene. A 20-month-old boy and his 8-year-old brother presented with polyuria, polydipsia, and failure to thrive. Both boys demonstrated partial DDAVP (1-desamino-8-D AVP or desmopressin) responses; thus, NDI diagnosis was delayed. While routine sequencing of AVPR2 showed a potential splice site variant, it was not until exome sequencing confirmed the AVPR2 splice site variant and did not reveal any more likely candidates that the patients' diagnosis was made and proper treatment was instituted. Both patients were hemizygous for two AVPR2 variants predicted in silico to affect AVPR2 messenger RNA (mRNA) splicing. A minigene assay revealed that the novel AVPR2 c.276A>G mutation creates a novel splice acceptor site leading to 5' truncation of AVPR2 exon 2 in HEK293 human kidney cells. Both patients have been treated with high-dose DDAVP with a remarkable improvement of their symptoms and accelerated linear growth and weight gain. We present here a unique case of partial X-linked NDI due to an AVPR2 splice site mutation; patients with diabetes insipidus of unknown etiology may harbor splice site mutations that are initially underestimated in their pathogenicity on sequence analysis. • X-linked nephrogenic diabetes insipidus is caused by AVPR2 mutations, and disease severity can vary depending on the functional effect of the mutation. What is New: • We demonstrate here that a splice site mutation in AVPR2 leads to partial X-linked NDI in two brothers. • Treatment with high-dose DDAVP led to improvement of polyuria and polydipsia, weight gain, and growth.

THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877) BY FYODOR DOSTOEVSKY

OpenAIRE

Elena A. Fedorova

2015-01-01

The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Kara...

A Clarion Call for Social Work Attention: Brothers and Sisters of Persons With Acquired Brain Injury in the United States.

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Degeneffe, Charles Edmund

2016-08-11

This article presents a clarion call for increased social work attention to the needs of siblings of persons with acquired brain injury (ABI) in the United States. The article overviews how siblings are psychosocially affected, how they provide care to the injured brothers and sisters, and how they personally develop as a result of their experiences. The article highlights the fact that social workers and other professionals often overlook the needs of siblings of persons with ABI and makes an appeal for social workers to advance clinical practice and research to benefit this often neglected population.

Gorlin-Goltz syndrome in twin brothers: an unusual occurrence with review of the literature.

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Anchlia, Sonal; Vyas, Siddharth; Bahl, Sumit; Nagavadiya, Vipul

2015-08-21

Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is caused by genetic alteration produced by a mutation in the 'patched' tumour suppressor gene, and is inherited in a dominant autosomal way. Although sporadic cases have been found, this syndrome has rarely been reported in twin patients. The syndrome is characterised by a wide range of developmental abnormalities and has a predisposition to neoplasms such as multiple pigmented basal cell carcinomas and keratocysts in jaws; it also has other features such as palmar and/or plantar pits and calcification of falx cerebri. Owing to the critical oral and maxillofacial manifestations of this syndrome, it is important to recognise its characteristics in order to make a diagnosis, and to plot early preventive treatment and establish the right genetic evidence. Based on a combination of imaging, clinical and histopathological findings, we present a diagnosed case of Gorlin-Goltz syndrome in 18-year-old twin brothers. All cystic lesions were enucleated and 1 year follow-up showed no recurrence. 2015 BMJ Publishing Group Ltd.

A Song in the Dark. Francis of Assisi’s Canticle of Brother Sun

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Speelman Willem Marie

2016-10-01

Full Text Available The Canticle of the Creatures or Canticle of Brother Sun is based on a particular way of perceiving reality. Francis, who had turned away from ‘the world’, discovered a different way of looking at it. This is a divine way of perceiving, in which the senses do not grasp reality, but accept it as it communicates itself. This way of perceiving is only possible if one does not attempt to master the environment, but allows one’s senses to be weak. It is significant, therefore, that this song of praise was born at a moment of the utmost despair and weakness. The song’s content is in line with this weak perception: it is not about Francis who praises God and (or for His creatures, but rather it is a testimony that the creatures-the elements-are already praising God, and a prayer that He should let Himself be praised by the creatures. Also in line with this weak perception is the fact that the creatures are praised just as they communicate themselves to Francis: as bodies. The theology of this song is that the creatures through their bodies resonate (strengthen, and colour the blessings that come from God, thereby making His blessing present here on earth. Francis’ role is to give a voice and a language to the heavenly praises as they resound in his environment. The transformative power of this song is that we, whether consciously or not, do the same thing when we participate in this song.

Gregorio y Francisco Esparza: hermanos enfrentados ante la independencia de Texas, 1835-1836 Gregorio and Francisco Esparza: Brothers Who Fought Each Other During the Independence of Texas, 1835-1836

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Gustavo Ernesto Emmerich

2012-08-01

Full Text Available En 1836 el ejército mexicano tomó el fuerte de El Álamo, en las afueras de San Antonio. Todos sus defensores, que combatían por la independencia de Texas, murieron en la acción, entre ellos Gregorio Esparza, un nativo de esa ciudad. Tras la batalla, su hermano Francisco, enrolado en el bando mexicano, le dio cristiana sepultura. Este artículo examina la saga de ambos hermanos virtualmente desconocida en México. La primera sección de este artículo contextualiza la independencia de Texas, la segunda contiene resultados de investigación documental realizada por el autor sobre Gregorio y Francisco Esparza. La tercera comenta una entrevista realizada a un hijo de Gregorio sobre los papeles de su padre y su tío en El Álamo. La cuarta evalúa críticamente las evidencias. La quinta ofrece una reflexión sobre los motivos que habrían llevado a los hermanos Esparza -y en general a la comunidad texana de origen mexicano- a enfrentarse respecto a la independencia de Texas y, finalmente, en los anexos se transcriben los registros parroquiales y censales de la época y se extractan y comentan diversos relatos del hijo de Gregorio y de otros descendientes.In 1836, the Mexican army captured Fort Alamo outside San Antonio. All its defenders, who were fighting for the independence of Texas, died in action. Among these was Gregorio Esparza, a native of that city. After this battle, his brother Francisco, enlisted in the Mexican army, gave him a Christian burial. This article examines the saga of the two brothers, virtually unknown in Mexico. The first section contextualizes the independence of Texas. The second contains the results of the author's documentary research on Gregorio and Francisco Esparza. The third comments on an interview with one of Gregorio's sons on the roles played by his father and uncle at The Alamo. The fourth critically evaluates the evidence. The fifth provides a reflection on the reasons that led the Esparza brothers -and the

Hasil Rancang Bangun Sistem ERP dengan SDLC Model Waterfall: Studi Kasus Sistem Inventori PT Pan Brothers, Tbk.

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Harijanto Pangestu

2012-12-01

Full Text Available Competition in the business world effects the use of information technology. To achieve competitive advantage in the global competition, PT Pan Brothers, Tbk. should establish an integrated information system based on ERP (Enterprise Resource Planning. With the ERP system, information will be accurate and up-todate to support strategic decision making. It takes conscientious planning in building the ERP system. Management information systems development projects have a very important role. One determining component is how to choose and use appropriate information systems development method. SDLC (system development life cycle is growing very rapidly along with the development of information technology. It is necessary to choose the right SDLC in building an integrated system based on ERP. Each SDLC models has advantages and disadvantages. SDLC models will only be optimal if used according to the situation and conditions. Waterfall model provides clear deliverables and milestones, good documentation, easy to understand, easy to implement, emphasizes on good procedural workmanship (precoding design. Some of its weaknesses are difficult to integrate risk management, high cost change documents, high administrative costs, often late completion thus.To avoid them, there should be a well-planned project management and steps properly so it can be on time and will not exceed budget.

Expression of the central growth regulator BIG BROTHER is regulated by multiple cis-elements

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Breuninger Holger

2012-03-01

Full Text Available Abstract Background Much of the organismal variation we observe in nature is due to differences in organ size. The observation that even closely related species can show large, stably inherited differences in organ size indicates a strong genetic component to the control of organ size. Despite recent progress in identifying factors controlling organ growth in plants, our overall understanding of this process remains limited, partly because the individual factors have not yet been connected into larger regulatory pathways or networks. To begin addressing this aim, we have studied the upstream regulation of expression of BIG BROTHER (BB, a central growth-control gene in Arabidopsis thaliana that prevents overgrowth of organs. Final organ size and BB expression levels are tightly correlated, implying the need for precise control of its expression. BB expression mirrors proliferative activity, yet the gene functions to limit proliferation, suggesting that it acts in an incoherent feedforward loop downstream of growth activators to prevent over-proliferation. Results To investigate the upstream regulation of BB we combined a promoter deletion analysis with a phylogenetic footprinting approach. We were able to narrow down important, highly conserved, cis-regulatory elements within the BB promoter. Promoter sequences of other Brassicaceae species were able to partially complement the A. thaliana bb-1 mutant, suggesting that at least within the Brassicaceae family the regulatory pathways are conserved. Conclusions This work underlines the complexity involved in precise quantitative control of gene expression and lays the foundation for identifying important upstream regulators that determine BB expression levels and thus final organ size.

Experiência do irmão sadio em relação à doença e hospitalização do irmão com câncer Experiencia del hermano saludable en relación a la enfermedad y hospitalización del hermano concáncer Experience of a healthy brother in relation to the disease and hospitalization of his brother with cancer

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Maria de Fátima de Lima Cheron

2011-01-01

Full Text Available OBJETIVO: Compreender o significado da experiência de ter um irmão com câncer na perspectiva do irmão sadio. MÉTODOS: Pesquisa descritiva de abordagem qualitativa. Foram realizadas entrevistas semiestruturadas com cinco irmãos de crianças com câncer assistidas em instituição filantrópica localizada no Município de São Paulo. RESULTADOS: O tema central tornando-se amadurecido com o sofrimento permitiu revelar que o irmão sadio torna-se amadurecido em razão do sofrimento que lhe é imposto no decorrer dos acontecimentos. Passa a valorizar a convivência familiar e os pequenos atos do cotidiano que lhe eram despercebidos. CONCLUSÃO: A equipe de saúde precisa reconhecer a experiência do irmão e incluí-lo no cuidado prestado em todas as fases da doença.OBJETIVO: Comprender el significado de la experiencia de tener un hermano con cáncer en la perspectiva del hermano saludable. MÉTODOS: Investigación descriptiva de abordaje cualitativo. Fueron realizadas entrevistas semiestructuradas con cinco hermanos de niños con cáncer asistidos en una institución filantrópica localizada en el Municipio de Sao Paulo. RESULTADOS: El tema central tornándose maduro con el sufrimiento permitió revelar que el hermano saludable madura en razón del sufrimiento que le es impuesto en el transcurso de los acontecimientos. Pasa a valorizar la convivencia familiar y los pequeños actos del cotidiano que le eran desapercibidos. CONCLUSIÓN: El equipo de salud necesita reconocer la experiencia del hermano e incluirlo en el cuidado prestado en todas las fases de la enfermedad.OBJECTIVE: To understand the meaning of the experience of having a sibling with cancer from the perspective of healthy brother. METHODS: A descriptive qualitative research approach. Semi-structured interviews were conducted with five siblings of children with cancer who were receiving care in a philanthropic institution located in São Paulo. RESULTS: The central theme that

Super Mario brothers and sisters: Associations between coplaying video games and sibling conflict and affection.

Science.gov (United States)

Coyne, Sarah M; Jensen, Alexander C; Smith, Nathan J; Erickson, Daniel H

2016-02-01

Video games can be played in many different contexts. This study examined associations between coplaying video games between siblings and levels of affection and conflict in the relationship. Participants were 508 adolescents (M age = 16.31 years of age, SD = 1.08) who completed questionnaires on video game use and sibling relationships. Participants were recruited from a large Northwestern city and a moderate city in the Mountain West of the United States. Video games played between siblings were coded by an independent sample to assess levels of physical aggression and prosocial behavior in each game. Playing video games with a sibling was associated with higher levels of sibling affection for both boys and girls, but higher levels of conflict for boys only. Playing a violent video game with a brother was associated with lower levels of conflict in the sibling relationship, whereas playing a prosocial video game was not related to any sibling outcome. The value of video games in sibling relationships will be discussed, with a focus on the type of game and the sex of the adolescent. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

A Significant Source for the Madeleine and Other Major Episodes in Combray: Proust's Intertextual Use of Pierre Loti's My Brother Yves

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Richard M. Berrong

2014-01-01

Full Text Available The most famous passage in Marcel Proust’s In Search of Lost Time , and one of the most famous passages in Western literature, is the moment when the narrator sips tea while eating a shell-shaped pastry called a madeleine and suddenly recalls very vividly an apparently long-forgotten scene from his childhood. From this episode Proust developed his theories about involuntary memory and its important role in our emotional welfare. Proust was an avid reader of the French novelist Pierre Loti when he was young. Contemporary accounts show that he was able to recite whole passages from Loti’s work in public from memory. This article demonstrates the extent to which Proust made intertextual use of scenes from Loti’s novel My Brother Yves in constructing the madeleine and other famous passages in Combray , the first section of In Search of Lost Time. It does not attempt to question the originality of Proust’s work. Rather, building on previous studies of intertextuality in Proust, it seeks to show how the author went about creating his work and dialoguing with at least some of his potential contemporary readers.

A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty

DEFF Research Database (Denmark)

Känsäkoski, Johanna; Raivio, Taneli; Juul, Anders

2015-01-01

BACKGROUND: Idiopathic central precocious puberty (ICPP) results from the premature reactivation of the hypothalamic-pituitary-gonadal axis leading to development of secondary sexual characteristics prior to 8 y in girls or 9 y in boys. Since the initial discovery of mutations in the maternally...... hypothalamic complementary DNA (cDNA) was investigated by PCR. RESULTS: One paternally inherited rare variant, c.1034G>A (p.Arg345His), was identified in one girl with ICPP and in her brother with early puberty. The variant is predicted to be deleterious by three different in silico prediction programs....... Expression of MKRN3 was confirmed in adult human hypothalamus. CONCLUSION: Our results are in line with previous studies in which paternally inherited MKRN3 mutations have been found both in males and in females with ICPP or early puberty. Our report further expands the set of MKRN3 mutations identified...

Financial Contagion in the BRICS Stock Markets: An empirical analysis of the Lehman Brothers Collapse and European Sovereign Debt Crisis

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DIRCEU PEREIRA

2018-01-01

Full Text Available This research analyzes and extends the study of contagion for BRICS emerging stock markets in the context of the last two international financial crises: the Lehman Brothers Bankruptcy Crisis and the European Sovereign Debt Crisis. We investigate changes in the relationship and the co-movements between BRICS markets in response to international shocks that are originated in advanced markets like USA and Europe. Employing data of daily stock market indices of BRICS countries, this research tests for contagion, examining the interactions and characteristics of price movements of BRICS stock markets by applying cointegration, causality and VECM/Gonzalo-Granger statistic and variance decomposition methodology on stock returns as a measure of perceived country risk. The results exhibit that both long-run and short-run relationships patterns exist between BRICS stock markets and have drastically changed during turbulent periods compared with tranquil period, pointing towards the occurrence of contagion phenomenon among BRICS markets during the last two crises. These findings also indicate that changes in the USA and the Euro Zone indices affect BRICS stock markets in the short-run, acting as a leading indicator for investing in BRICS markets. Also imply an increasing degree of global market integration, bringing major implications for portfolio diversification and policy makers.

Terapia de linguagem de irmãos com transtornos invasivos do desenvolvimento: estudo longitudinal Language therapy of brothers with pervasive developmental disorders: longitudinal study

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Andréa Regina Nunes Misquiatti

2010-01-01

Full Text Available O objetivo deste trabalho foi descrever o processo de intervenção fonoaudiológica de dois irmãos com transtornos invasivos do desenvolvimento, por meio de um estudo longitudinal de caso clínico. Participaram dois irmãos, um de nove e outro de 11 anos de idade, ambos do gênero masculino, com autismo (Caso 1 e transtorno invasivo do desenvolvimento sem outra especificação (Caso 2. Como procedimento de coleta e análise de dados foi realizado um estudo longitudinal, por meio de acompanhamento dos casos ao longo de quatro anos de intervenção fonoaudiológica. Foram realizadas filmagens durante as sessões de terapia, análise documental de informações dos prontuários referentes à anamnese, avaliação e relatórios terapêuticos fonoaudiológicos, exames e avaliações multidisciplinares. Em ambos os casos houve melhora no contato visual, na interação social, no vocabulário e na brincadeira simbólica. No Caso 1 ocorreu aumento de 2,0 para 6,2 atos comunicativos por minuto, no Caso 2 de 3,5 para 8,0 atos e ambos demonstraram predominância do meio verbal e maior variedade de funções comunicativas. Outros fatores influenciaram estes resultados, como a deficiência intelectual, a dinâmica familiar, os conflitos no relacionamento entre os irmãos e o ambiente escolar em que estavam inseridos. Confirmou-se a relevância do fonoaudiólogo em intervenções nos transtornos invasivos do desenvolvimento, junto a equipes multidisciplinares, para a discussão diagnóstica e de condutas mais adequadas. Estudos longitudinais podem contribuir para uma análise mais detalhada e fidedigna de intervenções terapêuticas nesses casos, para esclarecer lacunas existentes na literatura e subsidiar a atuação do fonoaudiólogo clínico.The aim of this research was to describe the language intervention process of two brothers with pervasive developmental disorders, through a longitudinal clinical case study. Two brothers - one nine and the other 11

Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: A 'Big Brother' evaluation

International Nuclear Information System (INIS)

Steenbakkers, Roel J.H.M.; Duppen, Joop C.; Fitton, Isabelle; Deurloo, Kirsten E.I.; Zijp, Lambert; Uitterhoeve, Apollonia L.J.; Rodrigus, Patrick T.R.; Kramer, Gijsbert W.P.; Bussink, Johan; Jaeger, Katrien De; Belderbos, Jose S.A.; Hart, Augustinus A.M.; Nowak, Peter J.C.M.; Herk, Marcel van; Rasch, Coen R.N.

2005-01-01

Background and purpose: To evaluate the process of target volume delineation in lung cancer for optimization of imaging, delineation protocol and delineation software. Patients and methods: Eleven radiation oncologists (observers) from five different institutions delineated the Gross Tumor Volume (GTV) including positive lymph nodes of 22 lung cancer patients (stages I-IIIB) on CT only. All radiation oncologist-computer interactions were recorded with a tool called 'Big Brother'. For each radiation oncologist and patient the following issues were analyzed: delineation time, number of delineated points and corrections, zoom levels, level and window (L/W) settings, CT slice changes, use of side windows (coronal and sagittal) and software button use. Results: The mean delineation time per GTV was 16 min (SD 10 min). The mean delineation time for lymph node positive patients was on average 3 min larger (P=0.02) than for lymph node negative patients. Many corrections (55%) were due to L/W change (e.g. delineating in mediastinum L/W and then correcting in lung L/W). For the lymph node region, a relatively large number of corrections was found (3.7 corr/cm 2 ), indicating that it was difficult to delineate lymph nodes. For the tumor-atelectasis region, a relative small number of corrections was found (1.0 corr/cm 2 ), indicating that including or excluding atelectasis into the GTV was a clinical decision. Inappropriate use of L/W settings was frequently found (e.g. 46% of all delineated points in the tumor-lung region were delineated in mediastinum L/W settings). Despite a large observer variation in cranial and caudal direction of 0.72 cm (1 SD), the coronal and sagittal side windows were not used in 45 and 60% of the cases, respectively. For the more difficult cases, observer variation was smaller when the coronal and sagittal side windows were used. Conclusions: With the 'Big Brother' tool a method was developed to trace the delineation process. The differences between

THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877 BY FYODOR DOSTOEVSKY

Directory of Open Access Journals (Sweden)

Elena A. Fedorova

2015-11-01

Full Text Available The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Karamazov” (in particular on the chapter “Th e Russian Monk”. As follows from the comparison of the texts the dominant qualities of the ideal image of a Russian saint are repentance, humility and suff ering, desire for purifi cation, spiritual ability to resist the evil. The ideal form of existence of Russian people becomes conciliarism. The type of historicism is the movement to the Last Judgment. Gospel allusions and metaphors reinforce the author’s interpretation. Th us, Dostoevsky carries on the dialogue with the evangelical word at an ideological, imaginative, genre, motive and narrative level of the text. Th e hallmark of the works of Fyodor Dostoevsky who followed the evangelical tradition, becomes a dialogical word.

A dictionary without definitions: romanticist science in the production and presentation of the Grimm brothers' German dictionary, 1838-1863.

Science.gov (United States)

Kistner, Kelly

2014-12-01

Between 1838 and 1863 the Grimm brothers led a collaborative research project to create a new kind of dictionary documenting the history of the German language. They imagined the work would present a scientific account of linguistic cohesiveness and strengthen German unity. However, their dictionary volumes (most of which were arranged and written by Jacob Grimm) would be variously criticized for their idiosyncratic character and ultimately seen as a poor, and even prejudicial, piece of scholarship. This paper argues that such criticisms may reflect a misunderstanding of the dictionary. I claim it can be best understood as an artifact of romanticist science and its epistemological privileging of subjective perception coupled with a deeply-held faith in inter-subjective congruence. Thus situated, it is a rare and detailed case of Romantic ideas and ideals applied to the scientific study of social artifacts. Moreover, the dictionary's organization, reception, and legacy provide insights into the changing landscape of scientific practice in Germany, showcasing the difficulties of implementing a romanticist vision of science amidst widening gaps between the public and professionals, generalists and specialists.

Realidade e ficção no Big Brother e no CQC: a promessa de transparência hiper-realista versus o encobrimento irônico e sedutor do real

OpenAIRE

Polydoro, Felipe

2010-01-01

A realidade tornou-se tema central de uma série de produtos midiáticos contemporâneos. Em variados meios (cinema, televisão, literatura, mídia impressa), alastram-se objetos que exploram a fronteira entre o real e a ficção e que atendem a um anseio por signos da realidade vivida. Neste trabalho, analisamos dois programas de televisão que refletem o fenômeno citado: o humorístico Custe o Que Custar (CQC) e o reality show Big Brother Brasil. A base para esta análise é a teoria de Jean Baudrilla...

Síndrome de Waardenburg: achados audiológicos em 2 irmãos Waardenburg's syndrome: audiological findings in 2 brothers

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Carlos Henrique F. Martins

2003-01-01

Full Text Available A síndrome de Waardenburg foi inicialmente descrita em 1951 por P.J. Waardenburg, como uma condição autossômica dominante que apresenta penetrância e expressividade variáveis de seus caracteres. Os sinais clínicos mais frequentes são: deslocamento lateral dos cantos internos dos olhos (telecanto, hiperplasia da porção medial dos supercílios (sinofris, base nasal proeminente e alargada, alterações na pigmentação da íris e da pele, surdez congênita, mecha branca frontal ou encanecimento precoce. Este estudo foi realizado em dois irmãos de uma família, que apresentavam características clínicas da síndrome de Waardenburg, entre elas a deficiência auditiva. Os pacientes foram submetidos à uma avaliação otorrinolaringológica, audiológica e genética.Waardenburg's Syndrome, first described in 1951 by P.J. Waardenburg, is an autossomal dominant condition with variable penetrance and expressivity of its features. The clinical signs are lateral displacement of the inner canthi of the eyes, confluent eyebrows, broad and prominent nasal root, pigmentation changes of the irises and skin, sensorineural deafness, white forelock or early graying of the hair. This study was based on two brothers who presented a typical clinical picture of Waardenburg's Syndrome, including hearing loss. Otolaryngological, audiological and genetical evaluations were conducted.

Neonatal hyperthyroidism: neonatal clinical course of two brothers born to a mother with Graves-Basedow disease, before and after total thyroidectomy.

Science.gov (United States)

Zuppa, A A; Sindico, P; Savarese, I; D'Andrea, V; Fracchiolla, A; Cota, F; Romagnoli, C

2007-04-01

About 1-2% of infants born to mothers with Graves' disease or Hashimoto's thyroiditis develop neonatal hyperthyroidism because of transplacental passage of IgG stimulating TSH receptors (TRAb). To evaluate the effect of maternal total thyroidectomy on neonatal clinical course. We describe two brothers born to a mother with Graves' disease, before and after total thyroidectomy. The first child showed persistent tachycardia, the presence of TRAb and a laboratory pattern of hyperthyroidism. Lugol's solution was started and then propylthiouracil was added. Digitalis, furosemide and diazepam were necessary for treatment of heart failure, hypertension and irritability. On the 70th day of life, hormone serum levels normalized and treatment was interrupted. TRAb normalized by the third month of life. The second infant was born 2 years after the mother underwent total thyroidectomy. In spite of a laboratory pattern of hyperthyroidism and positivity to TRAb, he showed only considerable weight loss, and no therapy was required. TRAb may persist after total thyroidectomy: clinical and instrumental follow-up of the newborn is recommended.

Duas variantes da representação do real na cultura midiática: o exorbitante Big Brother brasil e o circunspeto Edifício Master

Directory of Open Access Journals (Sweden)

Fernando Andacht

2005-06-01

Full Text Available The text aims at describing a remarkable phenomenon in our present day media culture: the representation of the real in television and cinema. Through the comparison between two audiovisual genres which deal with the real in the media, the Edificio Master documentary, directed by Eduardo Coutinho, and the Big Brother Brasil television program, the aim is to understand the cultural signification of two very different esthetic products that, nevertheless, share the dominant use of indexical signs, as their specific strategy. Without trying to minimize the obvious esthetic and ethic differences that exist between the reality show of the multinational company Endemol and the highly acclaimed Brazilian film, the article considers a fundamental tendency in present day media culture, namely, the techological and artistic production of an illusory intimacy at a distance, as a way of reflecting on identity. The functioning of the reality show aims at wrenching out of its orbit the normality of its participants, who must dwell in an abnormal place; the documentary, on the other hand, aims at offering a circumspect and moral vision of our everyday world, there where life takes place.

Deception and the death of Ilyusha: truth and the best interest of a dying child in The Brothers Karamazov.

Science.gov (United States)

Martin, Clancy

2014-10-01

For centuries, many physicians and parents assumed that it was ethically justifiable to lie to a dying child. The reasoning was clear. Because the lie would likely eliminate or prevent a concrete harm (the child's fear), and the lie is about a harm that is unavoidable anyway, a lie appeared to be the morally desirable thing to do. Today, the ethical consensus has shifted. Many doctors and other health professionals now argue that we have an obligation to tell children the cold, hard truth. In this article, I argue that "the cold, hard truth" (assuming we can know it with certainty) might not always be in the best interest of the patient. To illustrate the point, I analyze an episode in Dostoevsky's novel, The Brothers Karamazov, in which a child is dying, his father lies to him about it, and 2 doctors take very different approaches to the truth. Each of these individuals has a particular interest when it comes to the question of "the truth" about the death of Ilyusha. I use this story to ask whether it is ethically permissible to lie to a dying child and, if so, who has the moral authority to tell that lie. Copyright © 2014 by the American Academy of Pediatrics.

My elder brother Fr Prof.Benignus Józef Wanat OCD. Personal family reminiscences

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Edward Wanat

2016-12-01

Full Text Available Father Józef Benignus Wanat OCD was born in Frydrychowice, near Wadowice, into a large and impoverished farming family. He had seven brothers and one sister and was the third son of Franciszek and Maria Wanat. His hard working family was one of character displaying religious devotion, and demonstrating generosity to others in times of need. During the Nazi occupation, his parents took into their two-roomed house, a family of eight who were deprived of their own home in brutal circumstances. Out of necessity, and due to lack of space, the three oldest sons slept in the stable under the roof on a makeshift bed. After graduating from High School, and in answer to his calling, Benignus entered a novitiate in the Discalced Carmelites’ Monastery in Czerna. He completed his philosophy studies in Poznan and his theological studies at the Major Seminary of Discalced Carmelite Fathers in Kraków, where he was ordained a priest. In Krakow, at the Jagiellonian University’s Faculty of History and Philosophy, Fr. Benignus pursued extramural studies in the field of archives. He graduated from the Pontifical Academy of Theology in Kraków in the History of Art and having successfully defended his doctoral dissertation, he earned the the title of professor doctor. He was a member of the faculty of art in this university and he lectured on the History of Art of the Church with emphasis on European art. He was the founder of the Archives of the Discalced Carmelites in Czerna. He wrote prolifically on the History of Art of the Discalced Carmelite Order and the Discalced Carmelite Nuns researching and visiting many and various sites for his articles. This led to his magnumopus, a monograph on the Discalced Carmelite Order in Poland. He was elected several times as Provincial Superior of the Discalced Carmelites Province in Poland and he was appointed the first Provincial Superior of the Province of Kraków which included being the Prior of several monasteries

Submarine Hydrothermal Activity and Gold-Rich Mineralization at Brothers Volcano, Southern Kermadec Arc, New Zealand

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de Ronde, C. E.; Massoth, G. J.; Christenson, B. W.; Butterfield, D. A.; Ishibashi, J.; Hannington, M. D.; Ditchburn, B. G.; Embley, R. W.; Lupton, J. E.; Kamenetsky, D.; Reyes, A. G.; Lahr, J.; Takai, K.

2006-12-01

Brothers volcano is one of several hydrothermally active volcanoes that occur along the Kermadec active arc front, NE of New Zealand. It forms an elongate edifice 13 km long by 8 km across that strikes NW-SE. The volcano has a caldera with a basal diameter of ~3 km and a floor at 1,850 m below sea level, surrounded by 290 to 530 m high walls. A volcanic cone of dacite rises 350 m from the caldera floor and partially coalesces with the southern caldera wall. Three hydrothermal sites have been located; on the NW caldera wall, on the SE caldera wall, and on the dacite cone. The NW caldera vent site is a long-term hydrothermal system that is today dominated by evolved seawater but has had episodic injections of magmatic fluid. The SE caldera site represents the main upflow of a relatively well-established magmatic-hydrothermal system on the seafloor where sulfide-rich chimneys are extant. The cone site is a nascent magmatic-hydrothermal system where crack zones localize upwelling acidic waters. Each of these different vent sites represent diverse parts of an evolving hydrothermal system, any one of which may be typical of submarine volcanic arcs. Hydrothermal venting is today occurring at the NW caldera and cone sites. The former is characterized by high-temperature (up to 302°C) venting with pH down to 2.8, low Mg and SO4 values, Cl between 510 and 760 mM, elevated Si and increasing Fe and Mn values with increasing Cl concentrations, consistent with a mostly Cl-enriched endmember. By contrast, vent fluids from the cone site are gas-rich (up to 220 mM total gas), have temperatures 30 ppm) zones in some chimneys formed over a short period of time, coincident with pulses of magmatic fluid into the hydrothermal system.

Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages.

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Bidon, Tobias; Janke, Axel; Fain, Steven R; Eiken, Hans Geir; Hagen, Snorre B; Saarma, Urmas; Hallström, Björn M; Lecomte, Nicolas; Hailer, Frank

2014-06-01

Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained underexplored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390-kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found 1) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, 2) male-biased gene flow across continents and on phylogeographic time scales, and 3) male dispersal that links the Alaskan ABC islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be reevaluated. Recent advances in sequencing technology render the analysis of Y-chromosomal variation feasible, even in nonmodel organisms. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e

A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty.

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Känsäkoski, Johanna; Raivio, Taneli; Juul, Anders; Tommiska, Johanna

2015-12-01

Idiopathic central precocious puberty (ICPP) results from the premature reactivation of the hypothalamic-pituitary-gonadal axis leading to development of secondary sexual characteristics prior to 8 y in girls or 9 y in boys. Since the initial discovery of mutations in the maternally imprinted MKRN3 gene in 2013, several case reports have described mutations in this gene in ICPP patients from different populations, highlighting the importance of MKRN3 as a regulator of pubertal onset. We screened 29 Danish girls with ICPP for mutations in MKRN3. Expression of MKRN3 in human hypothalamic complementary DNA (cDNA) was investigated by PCR. One paternally inherited rare variant, c.1034G>A (p.Arg345His), was identified in one girl with ICPP and in her brother with early puberty. The variant is predicted to be deleterious by three different in silico prediction programs. Expression of MKRN3 was confirmed in adult human hypothalamus. Our results are in line with previous studies in which paternally inherited MKRN3 mutations have been found both in males and in females with ICPP or early puberty. Our report further expands the set of MKRN3 mutations identified in ICPP patients across diverse populations, thus supporting the major regulatory function of MKRN3 in pubertal onset.

Cross-cousin marriage among the Yanomamö shows evidence of parent-offspring conflict and mate competition between brothers.

Science.gov (United States)

Chagnon, Napoleon A; Lynch, Robert F; Shenk, Mary K; Hames, Raymond; Flinn, Mark V

2017-03-28

Marriage in many traditional societies often concerns the institutionalized exchange of reproductive partners among groups of kin. Such exchanges most often involve cross-cousins-marriage with the child of a parent's opposite-sex sibling-but it is unclear who benefits from these exchanges. Here we analyze the fitness consequences of marrying relatives among the Yanomamö from the Amazon. When individuals marry close kin, we find that ( i ) both husbands and wives have slightly lower fertility; ( ii ) offspring suffer from inbreeding depression; ( iii ) parents have more grandchildren; and ( iv ) siblings, especially brothers, benefit when their opposite-sex siblings marry relatives but not when their same-sex siblings do. Therefore, individuals seem to benefit when their children or opposite-sex siblings marry relatives but suffer costs when they, their parents, or same-sex siblings do. These asymmetric fitness outcomes suggest conflicts between parents and offspring and among siblings over optimal mating strategies. Parental control of marriages is reinforced by cultural norms prescribing cross-cousin marriage. We posit that local mate competition combined with parental control over marriages may escalate conflict between same-sex siblings who compete over mates, while simultaneously forging alliances between opposite-sex siblings. If these relationships are carried forward to subsequent generations, they may drive bilateral cross-cousin marriage rules. This study provides insights into the evolutionary importance of how kinship and reciprocity underlie conflicts over who controls mate choice and the origins of cross-cousin marriage prescriptions.

A novel homozygous AP4B1 mutation in two brothers with AP-4 deficiency syndrome and ocular anomalies.

Science.gov (United States)

Accogli, Andrea; Hamdan, Fadi F; Poulin, Chantal; Nassif, Christina; Rouleau, Guy A; Michaud, Jacques L; Srour, Myriam

2018-04-01

Adaptor protein complex-4 (AP-4) is a heterotetrameric protein complex which plays a key role in vesicle trafficking in neurons. Mutations in genes affecting different subunits of AP-4, including AP4B1, AP4E1, AP4S1, and AP4M1, have been recently associated with an autosomal recessive phenotype, consisting of spastic tetraplegia, and intellectual disability (ID). The overlapping clinical picture among individuals carrying mutations in any of these genes has prompted the terms "AP-4 deficiency syndrome" for this clinically recognizable phenotype. Using whole-exome sequencing, we identified a novel homozygous mutation (c.991C>T, p.Q331*, NM_006594.4) in AP4B1 in two siblings from a consanguineous Pakistani couple, who presented with severe ID, progressive spastic tetraplegia, epilepsy, and microcephaly. Sanger sequencing confirmed the mutation was homozygous in the siblings and heterozygous in the parents. Similar to previously reported individuals with AP4B1 mutations, brain MRI revealed ventriculomegaly and white matter loss. Interestingly, in addition to the typical facial gestalt reported in other AP-4 deficiency cases, the older brother presented with congenital left Horner syndrome, bilateral optic nerve atrophy and cataract, which have not been previously reported in this condition. In summary, we report a novel AP4B1 homozygous mutation in two siblings and review the phenotype of AP-4 deficiency, speculating on a possible role of AP-4 complex in eye development. © 2018 Wiley Periodicals, Inc.

Ehlers danlos syndrome in two siblings

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Das M

2005-01-01

Full Text Available Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.

AcEST: BP916278 [AcEST

Lifescience Database Archive (English)

Full Text Available DROER GG24967 OS=Drosophila erecta GN=GG24967 P... 33 9.2 tr|A4V047|A4V047_DROME Brother of odd with entrails...SFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails

Columbia River wildlife mitigation habitat evaluation procedures report: Scotch Creek Wildlife Area, Berg Brothers, and Douglas County pygmy rabbit projects

International Nuclear Information System (INIS)

Ashley, P.R.; Ratassepp, J.; Berger, M.; Judd, S.L.

1997-01-01

This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites

Columbia River Wildlife Mitigation Habitat Evaluation Procedures Report / Scotch Creek Wildlife Area, Berg Brothers, and Douglas County Pygmy Rabbit Projects.

Energy Technology Data Exchange (ETDEWEB)

Ashley, Paul R.

1997-01-01

This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites.

Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

DEFF Research Database (Denmark)

Vorwerk, P; Christoffersen, C T; Müller, J

1999-01-01

to be compound heterozygotes for mutations in the IR gene. The maternal allele was alternatively spliced in exon 17 due to a point mutation in the -1 donor splice site of the exon. The abnormal skipping of exon 17 shifts the amino acid reading frame and leads to a truncated IR, missing the entire tyrosine kinase......The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...... domain. In the correct spliced variant, the point mutation is silent and results in a normally translated IR. The paternal allele carries a missense mutation in the tyrosine kinase domain. All three cDNA variants were present in the lymphocytes of the patients. Purified IR from 293 cells overexpressing...

AcEST: BP915933 [AcEST

Lifescience Database Archive (English)

Full Text Available 9.1 tr|A4V047|A4V047_DROME Brother of odd with entrails limited, iso... 33 9.1 >tr|B4L9X7|B4L9X7_DROMO GI141...IITQPESGKPPNQPLHSPHEAMPSFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails

Bernoulli Brothers

Indian Academy of Sciences (India)

In the long, glorious history of mathematics, we come across ... family flourished in business, but afterwards, its descendants .... teaching calculus to contemporary renowned mathematicians including Guillaume FrancoiseAntoiRe de.

The Role of Family Background for Earnings in Rural China

DEFF Research Database (Denmark)

Eriksson, Tor Viking; Qiang, Zhang Ying

This paper provides estimates of brother income correlations for rural China. Brother correlations are a parsimonious measure of the importance of family and community background as determinants of individuals' economic status. We find internationally high levels of income similarity for brothers...

Reframing Paul’s sibling language in light of Jewish epistolary forms of address

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Kyu Seop Kim

2015-06-01

Full Text Available Recent scholars focus mainly on Paul’s use of ‘brothers (and sisters’ or ‘brother (and sister’ in Greco-Roman epistolary conventions and cultural backdrops. However, Jewish dimensions (particularly ethnic dimensions of Paul’s sibling language still remain unexplored in current scholarship. Furthermore, scholars have not drawn much attention to how Jewish letter writers use sibling terms in their letters. This article offers a new interpretation on Paul’s sibling language in light of its Jewish usage. We should note that Jewish letter writers did not address their Gentile letter recipients as ‘brother(s’. However, Paul did call his recipients ‘brothers’. It is unlikely that Paul employed sibling language without being aware of its common Jewish usage. The author proposes that Paul’s sibling language is used in the context of an ethnic insider designation (shared ethnicity, and that ascribing the title of brother to believers including Gentiles signals the re-definition of the family of Abraham.

Birth order and fluctuating asymmetry: a first look.

Science.gov (United States)

Lalumière, M L; Harris, G T; Rice, M E

1999-01-01

We investigated the hypothesis that maternal immunoreactivity to male-specific features of the foetus can increase developmental instability. We predicted that the participants' number of older brothers would be positively related to the fluctuating asymmetry of ten bilateral morphological traits. The participants were 40 adult male psychiatric patients and 31 adult male hospital employees. Consistent with the hypothesis, the participants' number of older brothers--but not number of older sisters, younger brothers or younger sisters--was positively associated with fluctuating asymmetry. The patients had significantly larger fluctuating asymmetry scores and tended to have more older brothers than the employees, but the positive relationship between the number of older brothers and fluctuating asymmetry was observed in both groups. PMID:10643079

Is the association between general cognitive ability and violent crime caused by family-level confounders?

Science.gov (United States)

Frisell, Thomas; Pawitan, Yudi; Långström, Niklas

2012-01-01

Research has consistently found lower cognitive ability to be related to increased risk for violent and other antisocial behaviour. Since this association has remained when adjusting for childhood socioeconomic position, ethnicity, and parental characteristics, it is often assumed to be causal, potentially mediated through school adjustment problems and conduct disorder. Socioeconomic differences are notoriously difficult to quantify, however, and it is possible that the association between intelligence and delinquency suffer substantial residual confounding. We linked longitudinal Swedish total population registers to study the association of general cognitive ability (intelligence) at age 18 (the Conscript Register, 1980-1993) with the incidence proportion of violent criminal convictions (the Crime Register, 1973-2009), among all men born in Sweden 1961-1975 (N = 700,514). Using probit regression, we controlled for measured childhood socioeconomic variables, and further employed sibling comparisons (family pedigree data from the Multi-Generation Register) to adjust for shared familial characteristics. Cognitive ability in early adulthood was inversely associated to having been convicted of a violent crime (β = -0.19, 95% CI: -0.19; -0.18), the association remained when adjusting for childhood socioeconomic factors (β = -0.18, 95% CI: -0.18; -0.17). The association was somewhat lower within half-brothers raised apart (β = -0.16, 95% CI: -0.18; -0.14), within half-brothers raised together (β = -0.13, 95% CI: (-0.15; -0.11), and lower still in full-brother pairs (β = -0.10, 95% CI: -0.11; -0.09). The attenuation among half-brothers raised together and full brothers was too strong to be attributed solely to attenuation from measurement error. Our results suggest that the association between general cognitive ability and violent criminality is confounded partly by factors shared by brothers. However, most of the association remains even

Is the association between general cognitive ability and violent crime caused by family-level confounders?

Directory of Open Access Journals (Sweden)

Thomas Frisell

Full Text Available BACKGROUND: Research has consistently found lower cognitive ability to be related to increased risk for violent and other antisocial behaviour. Since this association has remained when adjusting for childhood socioeconomic position, ethnicity, and parental characteristics, it is often assumed to be causal, potentially mediated through school adjustment problems and conduct disorder. Socioeconomic differences are notoriously difficult to quantify, however, and it is possible that the association between intelligence and delinquency suffer substantial residual confounding. METHODS: We linked longitudinal Swedish total population registers to study the association of general cognitive ability (intelligence at age 18 (the Conscript Register, 1980-1993 with the incidence proportion of violent criminal convictions (the Crime Register, 1973-2009, among all men born in Sweden 1961-1975 (N = 700,514. Using probit regression, we controlled for measured childhood socioeconomic variables, and further employed sibling comparisons (family pedigree data from the Multi-Generation Register to adjust for shared familial characteristics. RESULTS: Cognitive ability in early adulthood was inversely associated to having been convicted of a violent crime (β = -0.19, 95% CI: -0.19; -0.18, the association remained when adjusting for childhood socioeconomic factors (β = -0.18, 95% CI: -0.18; -0.17. The association was somewhat lower within half-brothers raised apart (β = -0.16, 95% CI: -0.18; -0.14, within half-brothers raised together (β = -0.13, 95% CI: (-0.15; -0.11, and lower still in full-brother pairs (β = -0.10, 95% CI: -0.11; -0.09. The attenuation among half-brothers raised together and full brothers was too strong to be attributed solely to attenuation from measurement error. DISCUSSION: Our results suggest that the association between general cognitive ability and violent criminality is confounded partly by factors shared by

Fraternal Birth Order, Family Size, and Male Homosexuality: Meta-Analysis of Studies Spanning 25 Years.

Science.gov (United States)

Blanchard, Ray

2018-01-01

The fraternal birth order effect is the tendency for older brothers to increase the odds of homosexuality in later-born males. This study compared the strength of the effect in subjects from small versus large families and in homosexual subjects with masculine versus feminine gender identities. Meta-analyses were conducted on 30 homosexual and 30 heterosexual groups from 26 studies, totaling 7140 homosexual and 12,837 heterosexual males. The magnitude of the fraternal birth order effect was measured with a novel variable, the Older Brothers Odds Ratio, computed as (homosexuals' older brothers ÷ homosexuals' other siblings) ÷ (heterosexuals' older brothers ÷ heterosexuals' other siblings), where other siblings = older sisters + younger brothers + younger sisters. An Older Brothers Odds Ratio of 1.00 represents no effect of sexual orientation; values over 1.00 are positive evidence for the fraternal birth order effect. Evidence for the reliability of the effect was consistent. The Older Brothers Odds Ratio was significantly >1.00 in 20 instances, >1.00 although not significantly in nine instances, and nonsignificantly <1.00 in 1 instance. The pooled Older Brothers Odds Ratio for all samples was 1.47, p < .00001. Subgroups analyses showed that the magnitude of the effect was significantly greater in the 12 feminine or transgender homosexual groups than in the other 18 homosexual groups. There was no evidence that the magnitude of the effect differs according to family size.

Interaction of birth order, handedness, and sexual orientation in the Kinsey interview data.

Science.gov (United States)

Bogaert, Anthony F; Blanchard, Ray; Crosthwait, Lesley E

2007-10-01

Recent evidence indicates that 2 of the most consistently observed correlates of men's sexual orientation--handedness and older brothers--may be linked interactively in their prediction of men's sexual orientation. In this article, the authors studied the relationship among handedness, older brothers, and men's sexual orientation in the large and historically significant database originally compiled by Alfred C. Kinsey and his colleagues (A. C. Kinsey, W. B. Pomeroy, & C. E. Martin, 1948). The results demonstrated that handedness moderates the relationship between older brothers and sexual orientation. Specifically, older brothers increased the odds of homosexuality in right-handers only; in non-righthanders, older brothers did not affect the odds of homosexuality. These results refine the possible biological explanations reported to underlie both the handedness and older brother relationships to men's sexual orientation. These results also suggest that biological explanations of men's sexual orientation are likely relevant across time, as the Kinsey data comprise an older cohort relative to modern samples. (PsycINFO Database Record (c) 2007 APA, all rights reserved).

Male sexual orientation in independent samoa: evidence for fraternal birth order and maternal fecundity effects.

Science.gov (United States)

VanderLaan, Doug P; Vasey, Paul L

2011-06-01

In Western cultures, male androphiles tend to have greater numbers of older brothers than male gynephiles (i.e., the fraternal birth order effect). In the non-Western nation of Independent Samoa, androphilic males (known locally as fa'afafine) have been shown to have greater numbers of older brothers, older sisters, and younger brothers (Vasey & VanderLaan, 2007). It is unclear, however, whether the observed older brother effect, in the context of the additional sibling category effects, represented a genuine fraternal birth order effect or was simply associated with elevated maternal fecundity. To differentiate between these two possibilities, this study employed a larger, independent replication sample of fa'afafine and gynephilic males from Independent Samoa. Fa'afafine had greater numbers of older brothers and sisters. The replication sample and the sample from Vasey and VanderLaan were then combined, facilitating a comparison that showed the older brother effect was significantly greater in magnitude than the older sister effect. These results suggest that fraternal birth order and maternal fecundity effects both exist in Samoa. The existence of these effects cross-culturally is discussed in the context of biological theories for the development of male androphilia.

Adult siblings of individuals with Down syndrome versus with autism: findings from a large-scale US survey.

Science.gov (United States)

Hodapp, R M; Urbano, R C

2007-12-01

As adults with Down syndrome live increasingly longer lives, their adult siblings will most likely assume caregiving responsibilities. Yet little is known about either the sibling relationship or the general functioning of these adult siblings. Using a national, web-based survey, this study compared adult siblings of individuals with Down syndrome to siblings of individuals with autism in terms of a potential 'Down syndrome advantage' and changes across age of the brother/sister with disabilities. Two groups were examined, siblings of persons with Down syndrome (n = 284) and with autism (n = 176). The Adult Sibling Questionnaire measured the number and length of contacts between siblings and their brothers/sisters with disabilities; the warmth, closeness and positiveness of the sibling relationship; and the sibling's overall levels of perceived health, depression and rewards of being a sibling. Compared with siblings of brothers/sisters with autism, siblings of brothers/sisters with Down syndrome showed closer, warmer sibling relationships, along with slightly better health, lower levels of depressive symptoms and more contacts. Across age groups of the brother/sister with disabilities, both groups showed lessened contacts, with less close sibling relationships occurring when brothers/sisters with disabilities were aged 30-44 years and 45 years and older (in Down syndrome) and 45 years and older (in autism). Within both groups, closer sibling relationships were associated with more frequent and lengthy contacts, brothers/sisters with disabilities who were better at maintaining friendships and had lower levels of behavioural/emotional problems, and siblings who felt themselves more rewarded by being a sibling to a brother/sister with disabilities. In line with earlier work on families of children with disabilities, this study shows an advantage for siblings of adults with Down syndrome, in terms of both sibling relationships and of slightly better health and

AcEST: BP918513 [AcEST

Lifescience Database Archive (English)

Full Text Available EAMPSFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails limited, isoform B ...E Brother of odd with entrails limited, iso... 33 9.9 >tr|B4L9X7|B4L9X7_DROMO GI14159 OS=Drosophila mojavens...8_DROER GG24967 OS=Drosophila erecta GN=GG24967 P... 33 9.9 tr|A4V047|A4V047_DROM

The Play Therapy Process of Sibling-Witnesses of Marital Violence

Directory of Open Access Journals (Sweden)

Miao-Jung Lin

2014-06-01

Full Text Available The purpose of this study is to explore play phases, play themes, and play behaviors in the play therapy processes of two siblings who were child witnesses of marital violence. Consensus qualitative research method was adopted to analyze the data. The results showed four phases in the siblings’ play therapies: the exploratory phase, the trauma phase, the transformation phase, and the ending phase. Within the four phases, same themes that were identified for both siblings were “exploration” in the exploratory phase, “destruction” in the trauma phase, and “blessing” in the ending phase. Differences in play themes were also identified to include “interaction”, “chaos”, “defensiveness”, “threatening” for the older brother during the trauma phase, while the younger of the two displayed “hostility”, “violence/aggression”, and “repetition”. In the transformation phase, the older brother displayed themes of “healing”, “nurturing/tending”, while the younger brother displayed themes of “protection”, “construction”, and “creation”. For the ending phase, the younger brother also displayed themes of “separation” and “wistfulness”. Some recommendations for practitioners and further research in play therapy are provided.

'Brothers in arms'

DEFF Research Database (Denmark)

Adamsen, L; Rasmussen, J M; Pedersen, L S

2001-01-01

The study investigated how a group intervention programme (13 sessions over 16 weeks), designed for men with cancer (n = 17), affected their sense of well-being and had a positive impact on their ability to cope with the physical, psychological and social consequences of living with cancer...

Gianco, my Brother

Science.gov (United States)

Rota, Ester Gasperoni

As a child, Gianco (the nickname by which he was known to family and friends) wanted to be a cook. Since cooking has never been my "cup of tea" I gladly allowed him to experiment on a stove that had been given to me for Christmas, a little electric marvel equipped with a real oven. He concocted sauces, baked cookies and cakes, which were eminently edible. Perhaps thanks to his childhood practice, Gianco's cooking was always far better than mine.

Band of Brothers

DEFF Research Database (Denmark)

Pærregaard, Karsten

2011-01-01

Kapitlet diskuterer den rolle, som katolske broderskaber spiller i peruanske migranters religiøse praksis i USA, Spanien og andre lande. Den introducerer kort de katolske broderskabers historie i Spanien og det kolonial Latin Amerika og undersøger derpå det spirituelle slægtskab, som forbinder pe...

Birth order and risk taking in athletics: a meta-analysis and study of major league baseball.

Science.gov (United States)

Sulloway, Frank J; Zweigenhaft, Richard L

2010-11-01

According to expectations derived from evolutionary theory, younger siblings are more likely than older siblings to participate in high-risk activities. The authors test this hypothesis by conducting a meta-analysis of 24 previous studies involving birth order and participation in dangerous sports. The odds of laterborns engaging in such activities were 1.48 times greater than for firstborns (N = 8,340). The authors also analyze performance data on 700 brothers who played major league baseball. Consistent with their greater expected propensity for risk taking, younger brothers were 10.6 times more likely to attempt the high-risk activity of base stealing and 3.2 times more likely to steal bases successfully (odds ratios). In addition, younger brothers were significantly superior to older brothers in overall batting success, including two measures associated with risk taking. As expected, significant heterogeneity among various performance measures for major league baseball players indicated that older and younger brothers excelled in different aspects of the game.

Understanding Adolescent Delinquency: The Role of Older Siblings’ Delinquency and Popularity with Peers

Science.gov (United States)

Craine, Jessica L.; Tanaka, Teri A.; Nishina, Adrienne; Conger, Katherine J.

2009-01-01

The present study examined delinquency concordance and the moderating effects of younger sibling perceptions of older sibling popularity in a sample of 587 adolescent sibling pairs. Using a social learning framework, and taking dyad composition into account, perceptions of popularity were hypothesized to strengthen siblings’ concordance for delinquency. Older sibling delinquency significantly predicted younger sibling delinquency. Older sibling popularity was not important in predicting boys’ delinquency. However, perceptions of older sibling popularity directly predicted reduced delinquency for girls with older sisters. A significant interaction effect was found for girls with older brothers. Older brother delinquency predicted girls’ delinquency for girls who perceived their older brother to be relatively popular. There was no delinquency concordance for girls who perceived their older brothers to be less popular. PMID:20305731

Detecting and correcting for family size differences in the study of sexual orientation and fraternal birth order.

Science.gov (United States)

Blanchard, Ray

2014-07-01

The term "fraternal birth order effect" denotes a statistical relation most commonly expressed in one of two ways: Older brothers increase the odds of homosexuality in later born males or, alternatively, homosexual men tend to have more older brothers than do heterosexual men. The demonstrability of this effect depends partly on the adequate matching of the homosexual and heterosexual study groups with respect to mean family size. If the homosexual group has too many siblings, relative to the heterosexual group, the homosexual group will tend to show the expected excess of older brothers but may also show an excess of other sibling-types (most likely older sisters); if the homosexual group has too few siblings, it will tend not to show a difference in number of older brothers but instead may show a deficiency of other sibling-types (most likely younger brothers and younger sisters). In the first part of this article, these consequences are illustrated with deliberately mismatched groups selected from archived data sets. In the second part, two slightly different methods for transforming raw sibling data are presented. These are intended to produce family-size-corrected variables for each of the four original sibling parameters (older brothers, older sisters, younger brothers, and younger sisters). Both versions are shown to render the fraternal birth order effect observable in the deliberately mismatched groups. In the third part of the article, fraternal birth order studies published in the last 5 years were surveyed for failures to find a statistically significant excess of older brothers for the homosexual group. Two such studies were found in the nine examined. In both cases, the collective findings for older sisters, younger brothers, and younger sisters suggested that the mean family size of the homosexual groups was smaller than that of the heterosexual comparison groups. Furthermore, the individual findings for the four classes of siblings resembled those

Preparing Your Child for a New Sibling (For Parents)

Science.gov (United States)

... Family Getting Along With Brothers and Sisters Kids Talk About: Brothers and Sisters View more ... All information on KidsHealth® is for educational purposes only. For specific medical advice, diagnoses, and ...

Predictors of future caregiving by adult siblings of individuals with intellectual and developmental disabilities.

Science.gov (United States)

Burke, Meghan M; Taylor, Julie Lounds; Urbano, Richard; Hodapp, Robert M

2012-01-01

With the growing life expectancy for individuals with intellectual and developmental disabilities, siblings will increasingly assume responsibility for the care of their brother or sister with intellectual and developmental disabilities. Using a 163-item survey completed by 757 siblings, the authors identified factors related to future caregiving expectations. Siblings expected to assume greater caregiving responsibility for their brother or sister with disabilities if they were female, had closer relationships with and lived closer to their brother or sister with intellectual and developmental disabilities, and were the lone sibling without a disability. Siblings who expected to assume higher levels of caregiving had parents who were currently more able to care for their brother or sister with disabilities. With a better understanding of who intends to fulfill future caregiving roles, support can be provided to these siblings.

The Impact of Sibling Sex Composition on Women's Educational Achievements: A Unique Natural Experiment by Twins Gender Shocks

OpenAIRE

Chen, Stacey; Chen, Yen-Chien; Liu, Jin-Tan

2008-01-01

In a pro-male biased society, brothers may reduce the parental investment re- ceived by female siblings, if parents face time or financial constraints. But brothers may also cause positive externalities. Using more than 12,000 ¯rstborn twins from a highly sex-imbalanced economy, Taiwan, we test if women have fewer opportunities to attend college if they have a brother rather than a sister. To minimize the prob- lem of sex selection, we exploit the fact that twin sex is random given the sex of...

Comparative Analysis of Liability Cases for Bankruptcies of Financial Institutions

Directory of Open Access Journals (Sweden)

Julija Kiršienė

2017-09-01

Full Text Available The bankruptcy of the fourth largest investment bank in the world Lehman Brothers Holdings Inc. in 2008 remains the largest bankruptcy in the history of United States. This bankruptcy is viewed as a turning point in the Global Financial Crisis. Paradoxically, even though the financial system had many safeguards (auditors, audit committees, the board of directors, credit rating agencies, government supervisors whose purpose was to inform the investing public about the actual financial situation of the institution, Lehman Brothers bankruptcy came as a shock to financial markets across the globe revealing that many of the “gatekeepers” failed. Comparative analysis of liability cases after bankruptcies of Lehman Brothers and financial institutions in Lithuania shows that contrary to Lehman’s case, the demise of financial institutions in Lithuania cannot be attributed to sub-prime mortgages caused financial crisis, real estate market fluctuations or any other external variable. Problems are related to weak supervision, inefficient regulation, and common unethical behavior in the financial sector.

An unusual occurrence of repeated single allele variation on Y-STR locus DYS458

Directory of Open Access Journals (Sweden)

Pankaj Shrivastava

2016-09-01

Full Text Available Six brothers were accused of gagging and raping a woman. A single male Y-STR profile was obtained from vaginal smear swab and clothes of the victim, which did not match with the DNA profile of the accused brothers. As a reference point, the blood sample of their father (aged 87 years was also analyzed with the same kit. The Y-STR haplotype of all six brothers was found to be the same as that of their father except at locus DYS458. At this locus, while the eldest, second and fourth siblings share allele 18 with their father, a loss of one repeat (allele 17 instead of 18 is observed in the third son while fifth and sixth siblings have allele 19 representing a gain of one repeat. Thus, two changes viz. a gain (twice and loss of one repeat at this locus in one generation is both interesting and unusual.

A study about siblings in the face of intellectual disability

Directory of Open Access Journals (Sweden)

Olga Lizasoain

2010-05-01

Full Text Available Research has shown that siblings of a person with intellectual disabilities can present problems of identification and socialization, the need for compensation, early adoption of large responsibilities, feelings of abandonment, guilt, shame or sadness. Nevertheless, if the needs of these brothers and sisters are facing, disability can become a source of personal and family enrichment. This article presents the initial conclusions drawn after a series of personal interviews conducted with siblings of students in a special education school. Awareness of the issue leads us to approach this study with the aim of providing guidelines of intervention to help siblings to minimize the potential negative impact of having a brother or sister with intellectual disabilities, and facilitate the development of attitudes and behaviours that enable them to face stressful situations in a constructive manner. Thanks to the direct experience of those who have been confronted with this situation, is issued to prevent psychosocial problems associated with having a brother or sister with these features.

Kinship, Family, and Gender Effects in the Ultimatum Game.

Science.gov (United States)

Macfarlan, Shane J; Quinlan, Robert J

2008-09-01

Kinship and reciprocity are two main predictors of altruism. The ultimatum game has been used to study altruism in many small-scale societies. We used the ultimatum game to examine effects of individuals' family and kin relations on altruistic behavior in a kin-based horticultural community in rural Dominica. Results show sex-specific effects of kin on ultimatum game play. Average coefficient of relatedness to the village was negatively associated with women's ultimatum game proposals and had little effect on men's proposals. Number of brothers in the village was positively associated with men's ultimatum game proposals and negatively associated with women's proposals. Similarly, presence of father in the village was associated with higher proposals by men and lower proposals by women. We interpret the effect of brothers on men's proposals as a consequence of local competition among brothers. We speculate that daughter-biased parental care in this community creates a sense of entitlement among women with brothers, which may explain the inverse relation between number of brothers and women's ultimatum game proposals. The pattern of results may be consistent with how matrifocality affects cultural models of fairness differently along gender and family lines.

An unusual occurrence of repeated single allele variation on Y-STR locus DYS458

OpenAIRE

Shrivastava, Pankaj; Trivedi, Veena Ben; Jain, Toshi; Ali, Mehmood

2016-01-01

Six brothers were accused of gagging and raping a woman. A single male Y-STR profile was obtained from vaginal smear swab and clothes of the victim, which did not match with the DNA profile of the accused brothers. As a reference point, the blood sample of their father (aged 87 years) was also analyzed with the same kit. The Y-STR haplotype of all six brothers was found to be the same as that of their father except at locus DYS458. At this locus, while the eldest, second and fourth siblings s...

The Idea of Dialogue, Trust and Reconciliation in the Pilgrimage of Trust on Earth

Directory of Open Access Journals (Sweden)

Katarzyńska Agnieszka

2016-12-01

Full Text Available The purpose of this article is to present the Pilgrimage of Trust on Earth organized by the brothers of Taizé Community as an event building a relationship of dialogue, trust and reconciliation between nations and cultures. The article features an in-depth discussion of the elements of youth meetings and their impact on developing an attitude of dialogue and trust. We will briefly discuss the means used by the brothers to develop a dialogue between people, as well as the methods of spreading the idea of dialogue, trust and solidarity in interpersonal and international relations.

Lady Mary Sidney Herbert a Lady Mary Wroth: labutí píseň a imaginativní svět jako součást rodinného odkazu (Lady Mary Sidney Herbert and Lady Mary Wroth: a Swan song and Fictional World as a part of Sidneyan legacy

Directory of Open Access Journals (Sweden)

Martina Kastnerová

2017-03-01

Full Text Available The study intends to clarify the process of forming of Sidneyan literary cult as a part of (Sidneyʼs family legacy based on the the literary activities of Sidneyʼs sister Lady Mary Sidney Herbert, countess of Pembroke, and his niece Lady Mary Wroth, daughter of his younger brother Robert. Mary Sidney Herbert throughout her literary career sings a swan song of her brother, Mary Wroth creates an imaginative world of free love choice and happy endings and her literary career is based on the well-established cult of Sidneyʼs name.

To determine whether first-degree male relatives of women with polycystic ovary syndrome are at higher risk of developing cardiovascular disease and type II diabetes mellitus.

Science.gov (United States)

Hunter, A; Vimplis, S; Sharma, A; Eid, N; Atiomo, W

2007-08-01

The aim of this study was to determine whether first-degree male relatives of women with polycystic ovary syndrome (PCOS) were at increased risk of cardiovascular disease (CVD) and diabetes mellitus (type II DM). In a cross-sectional study, 60 women with PCOS and 112 controls were given a questionnaire. The prevalence of heart disease, stroke, diabetes and associated risk factors among fathers and brothers of women with PCOS and controls, were measured. The percentage of women with PCOS with at least one brother with a risk factor for CVD was 47.5%, around twice that seen in control women (24.71%). The prevalence of heart disease, stroke and diabetes were similar in brothers of women with PCOS and controls. In conclusion, brothers of women with PCOS may be at increased risk of CVD. They form an easily identified group, which can be targeted for primary prevention.

Sexual offending runs in families: A 37-year nationwide study.

Science.gov (United States)

Långström, Niklas; Babchishin, Kelly M; Fazel, Seena; Lichtenstein, Paul; Frisell, Thomas

2015-04-01

Sexual crime is an important public health concern. The possible causes of sexual aggression, however, remain uncertain. We examined familial aggregation and the contribution of genetic and environmental factors to sexual crime by linking longitudinal, nationwide Swedish crime and multigenerational family registers. We included all men convicted of any sexual offence (N = 21,566), specifically rape of an adult (N = 6131) and child molestation (N = 4465), from 1973 to 2009. Sexual crime rates among fathers and brothers of sexual offenders were compared with corresponding rates in fathers and brothers of age-matched population control men without sexual crime convictions. We also modelled the relative influence of genetic and environmental factors to the liability of sexual offending. We found strong familial aggregation of sexual crime [odds ratio (OR) = 5.1, 95% confidence interval (CI) = 4.5-5.9] among full brothers of convicted sexual offenders. Familial aggregation was lower in father-son dyads (OR = 3.7, 95% CI = 3.2-4.4) among paternal half-brothers (OR = 2.1, 95% CI = 1.5-2.9) and maternal half-brothers (OR = 1.7, 95% CI = 1.2-2.4). Statistical modelling of the strength and patterns of familial aggregation suggested that genetic factors (40%) and non-shared environmental factors (58%) explained the liability to offend sexually more than shared environmental influences (2%). Further, genetic effects tended to be weaker for rape of an adult (19%) than for child molestation (46%). We report strong evidence of familial clustering of sexual offending, primarily accounted for by genes rather than shared environmental influences. Future research should possibly test the effectiveness of selective prevention efforts for male first-degree relatives of sexually aggressive individuals, and consider familial risk in sexual violence risk assessment.

Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

DEFF Research Database (Denmark)

Klein, H H; Müller, R; Vestergaard, H

1999-01-01

We studied insulin receptor kinase activation in two brothers with congenital muscle fibre type disproportion myopathy and compound heterozygous mutations of the insulin receptor gene, their parents, and their unaffected brother. In the father who has a heterozygote Arg1174-->Gln mutation, in sit...

In de ban van het incestverbod : analyse van een historische omslag in de verbeelding van erotiek tussen broer en zuster

NARCIS (Netherlands)

Coebergh-van der Marck, Marie-Anne

2012-01-01

Central in the representation of eroticism between brother and sister, classical theme in litterature and film, stands the incest prohibition as source of tension between similarity and difference. Brother and sister share the same genes and because of this they belong together and go different

Sibling rivalry and the gender gap: evidence from child health outcomes in Ghana.

Science.gov (United States)

Garg, A; Morduch, J

1998-01-01

"When capital and labor markets are imperfect, choice sets narrow, and parents must choose how to ration available funds and time between their children. One consequence is that children become rivals for household resources. In economies with pro-male bias, such rivalries can yield gains to having relatively more sisters than brothers. Using a rich household survey from Ghana [the 1988-1989 Ghana Living Standards Survey], we find that on average if children had all sisters (and no brothers) they would do roughly 25-40% better on measured health indicators than if they had all brothers (and no sisters)." excerpt

Evidence for homosexuality gene

Energy Technology Data Exchange (ETDEWEB)

Pool, R.

1993-07-16

A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality. When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes. This led them to search the X chromosome for genes predisposing to homosexuality. The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common. Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome. The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality. The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally. And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers. It seems likely that homosexuality arises from a variety of causes.

Hepatic Encephalopathy

Medline Plus

Full Text Available ... to continue to work to my full capacity? Will I be able to drive? Patient Stories Angie M. Caregiver for Brother Charles DiAngelo Hepatic Encephalopathy Jason Dedmon Alcohol-related Cirrhosis ...

Big Brother Not Needed.

Science.gov (United States)

Heinen, Edward

1983-01-01

Cites the recent United States State Department's labeling of recent Canadian films--one on nuclear war and two on acid rain--as political propaganda as a sign of the need to review the nature of propaganda. Suggests that teaching students to intelligently evaluate propaganda is preferable to submitting to government dictum. (MM)

Mercury is Moon's brother

International Nuclear Information System (INIS)

Ksanfomalifi, L.V.

1976-01-01

The latest information on Mercury planet is presented obtained by studying the planet with the aid of radar and space vehicles. Rotation of Mercury about its axis has been discovered; within 2/3 of its year it executes a complete revolution about its axis. In images obtained by the ''Mariner-10'' Mercurys surface differs little from that of the Moon. The ''Mariner-10'' has also discovered the Mercurys atmosphere, which consists of extremely rarefied helium. The helium is continuously supplied to the planet by the solar wind. The Mercury's magnetic field has been discovered, whose strength is 35 x 10 -4 at the Equator and 70 x 10 -4 E at the poles. The inclination of the dipole axis to the Mercury's rotation axis is 7 deg

Brothers Grimm. [Lesson Plan].

Science.gov (United States)

Discovery Communications, Inc., Bethesda, MD.

Based on Grimm's fairy tales, this lesson plan presents activities designed to help students understand that fairy tales connect them to earlier generations, help them think about present situations, that magic figures prominently in fairy tales, and that fairy tales can inspire readers to create original works of art. The main activity in the…

The Driver Whose Heart Was Full of Sand: Leigh's Story--A Play Therapy Case Study of a Bereaved Child

Science.gov (United States)

Robson, Maggie

2008-01-01

This paper describes the therapeutic journey of Leigh (not his real name), a nine-year-old boy who was referred for play therapy due to the death of his 15-year-old brother. The play therapy was offered through a joint project called "Playing through Loss" and run jointly between a UK university and the local branch of a national…

Experience of Linguo-rhetoric Approach Realization in the Process of Classical Writer Literal Personality Idiodiscourse

Directory of Open Access Journals (Sweden)

Vladlena V. Siganova

2012-05-01

Full Text Available The article characterizes major results of integrated linguo-rhetoric approach application to writer’s idiodiscourse (F.M. Dostoevsky’s ‘The Brothers Karamazov’ case study.

Asperger's in the Holmes family.

Science.gov (United States)

Altschuler, Eric L

2013-09-01

I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock.

38 CFR 1.10 - Eligibility for and disposition of the United States flag for burial purposes.

Science.gov (United States)

2010-07-01

... separation from such service under conditions other than dishonorable, on or after April 25, 1951. (Authority... issued a flag on application signed by guardian). (iii) Parents, including adoptive, stepparents, and foster parents. (iv) Brothers or sisters, including brothers or sisters of the halfblood. (v) Uncles or...

[The sibling status effects and the personality scales of the MMPI].

Science.gov (United States)

Hama, H; Mine, H; Mine, H; Matsuyama, Y

1987-06-01

The purpose of this study is to find out if the personalities of siblings are similar or different. Subjects used were Doshisha University students and members of their families, provided those families had only two children. Altogether 29 pairs of boys and their younger brothers, 47 pairs of boys and their younger sisters, 44 pairs of girls and their younger brothers, and 51 pairs of girls and their younger sisters were given the MMPI individually. Sibling status effects were found in many of the MMPI scores according to the type of sibling dyads and birth order, especially for the sibling dyad of elder brother and younger sister. Personality relationships between the first and second child showed that there were significant correlations in many MMPI scales: L, K, Pd, Pa, Pt, Sc, Si, Conflict resolution, Manifest anxiety, Repression-Sensitization, and Hostility. Among the four types of sibling dyad, the pairs of girls and their younger brothers showed the highest correlation in their personality.

Cine-club

CERN Document Server

Ciné-club

2013-01-01

Thursday 26 September 2013 at 20:00 CERN Council Chamber The Wind that Shakes the Barley Directed by Ken Loach (UK, 2006) Original version english; french subtitles; 127 minutes Ireland, 1920. Damien and Teddy are brothers. But while the latter is already the leader of a guerrilla squad fighting for the independence of his motherland, Damien, a medical graduate of University College, would rather further his training at the London hospital where he has found a place. However, shortly before his departure, he happens to witness atrocities committed by the ferocious Black and Tans and finally decides to join the resistance group led by Teddy. The two brothers fight side by side until a truce is signed. But peace is short-lived and when one faction of the freedom-fighters accepts a treaty with the British that is regarded as unfair by the other faction, a civil war ensues, pitting Irishmen against Irishmen, brothers against brothers, Teddy against Damien... http://cineclub.web.cern.ch/Cineclub/

Cine club

CERN Document Server

Cine club

2017-01-01

Wednesday 21 June 2017 at 20:00 CERN Council Chamber Soul Kitchen Directed by Fatih Akin Germany / France / Italy, 2009, 99 minutes In Hamburg, Zinos has a restaurant serving poor-man's fare; he gets by, but his girlfriend has taken a job in Shanghai, he's hurt his back and can't cook, his feckless brother can be on daily parole from jail only if Zinos employs him (though his brother doesn't want to work), a school acquaintance wants to buy the restaurant property, and the tax authority and health inspector are on his case. Zinos hires a temperamental chef and loses all his customers, signs a power of attorney giving his brother full authority at the restaurant, and buys a ticket to Shanghai. Is this a recipe for disaster? Original version German / Greek / Spanish / Turkish / English; English subtitles Wednesday 28 June 2017 at 20:00 CERN Council Chamber In July (Im Juli) Directed by Fatih Akin Germany, 2000, 99 minutes Daniel is a young teacher who, in contrast to ever...

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African Journals Online (AJOL)

Owner

River (1966) in early school, and the name stuck in my memory. Again, my elder brother and his ... I recall that I had tried to make sense of the book. I flipped through my brother's copy. I could ... a rainbow of many colours. The challenge is for ...

20 CFR 633.320 - Nepotism.

Science.gov (United States)

2010-04-01

... family” means wife, husband, son, daughter, mother, father, brother, brother-in-law, sister, sister-in... position funded under the Act if a member of that person's immediate family is engaged in an administrative... the Act, if a member of that person's immediate family is engaged in an administrative capacity for...

Asperger's in the Holmes Family

Science.gov (United States)

Altschuler, Eric L.

2013-01-01

I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock.

20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.

Science.gov (United States)

2010-04-01

... surviving spouse or child, or the surviving dependent brothers or sisters, where there is no surviving... part the term “total disability” shall mean partial disability with respect to a claim for which... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and...

10 CFR 1060.501 - Definitions.

Science.gov (United States)

2010-01-01

... Uniformed Service. (e) Handicapped individual means a person who has a physical or mental disability or..., by blood, marriage, or operation of law, as father, mother, son, daughter, brother, sister, uncle..., father-in-law, mother-in-law, son-in-law, daughter-in-law, brother-in-law, sister-in-law, stepfather...

38 CFR 17.170 - Autopsies.

Science.gov (United States)

2010-07-01

... preference among such persons. Usually the spouse is first entitled, except in some situations of separation; followed by children, parents, brothers and sisters, etc. When the next of kin as defined by the laws of decedent's domicile consists of a number of persons as children, parents, brothers and sisters, etc...

Association among number, order and type of siblings and adolescent mental health at age 12.

Science.gov (United States)

Liu, Jufen; Sekine, Michikazu; Tatsuse, Takashi; Fujimura, Yuko; Hamanishi, Shimako; Zheng, Xiaoying

2015-10-01

Although the sibling relationship is a unique one, the effects of the number and type of siblings on mental health among adolescents have not been reported. Japanese children (total, 9276; boys, 4654; girls, 4622), all 12 years old, and from the Japanese Toyama Birth Cohort Study, were followed up until 2002. Subject self-reported mental health was obtained from the Japanese version of the Dartmouth Primary Care Co-operative Project (COOP) charts. The associations between number and type of siblings and self-reported mental health were examined. There was a significant difference in mental health between different sibling pairs, with brother pairs and brother/sister pairs having a positive effect on adolescent mental health, compared with those in sister pairs. Girls with brothers had better self-reported mental health than those without. The adjusted OR of good mental health was 1.44 (95%CI:1.00-2.08) for those with an older brother and 1.67 (95%CI: 1.17-2.38) for those with a younger brother compared with those without. Boys with a younger sister had a higher OR of good self-reported health than those without (OR, 1.62; 95%CI: 1.08-2.43). Children with siblings had better mental health status than those without, which has practical implications for Asian countries and worldwide considering the declining fertility. © 2015 Japan Pediatric Society.

How many gay men owe their sexual orientation to fraternal birth order?

Science.gov (United States)

Cantor, James M; Blanchard, Ray; Paterson, Andrew D; Bogaert, Anthony F

2002-02-01

In men, sexual orientation correlates with the number of older brothers, each additional older brother increasing the odds of homosexuality by approximately 33%. However, this phenomenon, the fraternal birth order effect, accounts for the sexual orientation of only a proportion of gay men. To estimate the size of this proportion, we derived generalized forms of two epidemiological statistics, the attributable fraction and the population attributable fraction, which quantify the relationship between a condition and prior exposure to an agent that can cause it. In their common forms, these statistics are calculable only for 2 levels of exposure: exposed versus not-exposed. We developed a method applicable to agents with multiple levels of exposure--in this case, number of older brothers. This noniterative method, which requires the odds ratio from a prior logistic regression analysis, was then applied to a large contemporary sample of gay men. The results showed that roughly 1 gay man in 7 owes his sexual orientation to the fraternal birth order effect. They also showed that the effect of fraternal birth order would exceed all other causes of homosexuality in groups of gay men with 3 or more older brothers and would precisely equal all other causes in a theoretical group with 2.5 older brothers. Implications are suggested for the gay sib-pair linkage method of identifying genetic loci for homosexuality.

Effects of gender difference and birth order on perceived parenting styles, measured by the EMBU scale, in Japanese two-sibling subjects.

Science.gov (United States)

Someya, T; Uehara, T; Kadowaki, M; Tang, S W; Takahashi, S

2000-02-01

The relationship between Egna Minnen av Barndoms Uppforstran (EMBU) scaling and gender, birth order and parents' gender was previously investigated in a large volunteer sample; significant interactions among the variables were found. In the present study, 730 Japanese volunteers with one sibling were used as subjects in order to control the number of siblings: the effect of gender of subjects and siblings and birth order on the perceived parenting style was examined. Based on gender and birth orders, 730 subjects were grouped into the following categories: (i) male with a younger brother; (ii) male with a younger sister; (iii) male with an older brother; (iv) male with an older sister; (v) female with a younger brother; (vi) female with a younger sister; (vii) female with an older brother; and (viii) female with an older sister. One-way ANOVA was performed with each EMBU subscale used as a dependent variable and these eight groups as independent variables. The scores for rejection and emotional warmth of father were influenced significantly by the pattern of siblings (Pchildren strongly experienced parenting style as more rejecting than others, and female children (elder sisters with brother, or younger sisters with sister) recognized parenting style as more caring and demonstrated more warmth than others. The results confirmed a significant interaction of gender of subjects and siblings and birth order of perceived parental rearing behavior.

Case Report: Allgrove syndrome: an Egyptian family with two ...

African Journals Online (AJOL)

Moderate achalasia developed at 9 years in the older brother and showed a slowly progressive course with development of chest pain and dysphagia. Alacrima was not evident before the age of 12 years. The neurological symptoms were less severe in the younger brother. He suffered alacrima that started at age of 11 ...

Mutant ApoA-1 Amyloidosis in a Family of Five Siblings With Motor Neuron Disease and Dementia

DEFF Research Database (Denmark)

Vrethema, Magnus; Mucchiano, Gerd Ingrid

2011-01-01

We present a family of fi ve siblings in which three brothers died of motor neuron disease (MND) and in two of them concomitant with dementia. A fourth brother died of myocardial infarction and was found to have extensive aortic intimal apolipoprotein A-1 (ApoA-1) derived amyloid deposits and apo...

20 CFR 410.515 - Modification of benefit amounts; general.

Science.gov (United States)

2010-04-01

..., parent, brother, or sister, the excess earnings from wages and from net earnings from self-employment (see § 410.530) of such miner, parent, brother, or sister, respectively; or (2) Failure to report...); or (3) The receipt by a beneficiary of payments made because of the disability of the miner due to...

20 CFR 725.533 - Modification of benefits amounts; general.

Science.gov (United States)

2010-04-01

... partial or total disability due to pneumoconiosis; or (3) In the case of benefits to a parent, brother, or... because of death or partial or total disability due to pneumoconiosis; or (2) Any compensation or benefits... (see § 410.530 of this title) of such parent, brother, sister, or miner, respectively; or (4) The fact...

SCHREINER HOUSE

African Journals Online (AJOL)

home after her father's insolvency. Her brother. Theo (23 in 1867), headmaster of the local public school, was head of the little household, with their sister Ettie (17) as housekeeper. In the following year their younger brother Will, then eleven, joined them. The four remained together until 1870 when. Thea and Will went to ...

Book Talk. Books About All Kinds of Heroes.

Science.gov (United States)

Freeman, Judy

1998-01-01

Presents an annotated listing of books about all kinds of heroes for elementary school students. Stories include the young King Arthur; an assertive, baseball-playing heroine who becomes a princess; an older brother dealing with his younger brother; a Christmas story; civil rights icon Rosa Parks; and the cow who jumped over the moon. (SM)

South African Journal of Philosophy - Vol 32, No 1 (2013)

African Journals Online (AJOL)

Am I My Brother's Keeper? On Personal Identity and Responsibility · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ... Is the Choice on Termination of Pregnancy Act Guilty of Disability Discrimination? EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Hall, 36-46.

Epilepsy phenotypes in siblings with Norrie disease.

Science.gov (United States)

Okumura, Akihisa; Arai, Eisuke; Kitamura, Yuri; Abe, Shinpei; Ikeno, Mitsuru; Fujimaki, Takuro; Yamamoto, Toshiyuki; Shimizu, Toshiaki

2015-11-01

Norrie disease is an X-linked recessive disorder that is characterized by congenital blindness. Although epileptic seizures are observed in some patients with Norrie disease, little is known about this phenomenon. Here, we report the manifestation of epilepsy in siblings with Norrie disease to increase our knowledge of epilepsy in this condition. Three brothers with congenital blindness were diagnosed with Norrie disease after genetic analyses indicated the deletion of exon 2 of the NDP gene. The eldest brother had suffered from epileptic seizures since the age of 11years, and his seizures were resistant to antiepileptic drugs. Although the second brother had no epileptic seizures, the youngest sibling had experiences epileptic seizures since the age of 8years. His seizures were controlled using lamotrigine and levetiracetam. An electroencephalography (EEG) revealed epileptiform discharges in the occipital areas in all three brothers. A study of these patients will increase our knowledge of epilepsy in patients with Norrie disease. Copyright © 2015 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

The Role of Gender in Youth Mentoring Relationship Formation and Duration

Science.gov (United States)

Rhodes, Jean; Lowe, Sarah R.; Litchfield, Leon; Walsh-Samp, Kathy

2008-01-01

The role of gender in shaping the course and quality of adult-youth mentoring relationships was examined. The study drew on data from a large, random assignment evaluation of Big Brothers Big Sisters of America (BBSA) programs [Grossman, J. B., & Tierney, J. P. (1998). Does mentoring work? An impact study of the Big Brothers Big Sisters program.…

Storytelling for a Nation

DEFF Research Database (Denmark)

Schubart, Rikke

2007-01-01

The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)......The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)...

Adolescent Siblings of Individuals with an Autism Spectrum Disorder: Testing a Diathesis-Stress Model of Sibling Well-Being

Science.gov (United States)

Orsmond, Gael I.; Seltzer, Marsha Mailick

2009-01-01

The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated…

20 CFR 410.510 - Computation of benefits.

Science.gov (United States)

2010-04-01

... surviving child of a miner or widow, or a parent, brother, or sister of a miner, is entitled to benefits for..., brother, or sister of a miner, who establishes entitlement to benefits under the provisions of subpart B... benefits) based on the disability or death due to pneumoconiosis arising out of the coal mine employment of...

20 CFR 725.520 - Computation of benefits.

Science.gov (United States)

2010-04-01

... parent, brother, or sister of a miner, is entitled to benefits for a month for which he or she is the... surviving child of a miner or surviving spouse, or a surviving parent, brother, or sister of a miner, who... dependent for purposes of augmentation of benefits) based on the disability or death due to pneumoconiosis...

Maailma börsid uues pöörises / Sirje Rank

Index Scriptorium Estoniae

Rank, Sirje, 1966-

2008-01-01

USA-st alanud finantskriis kogub uut hoogu. Investeerimispanga Lehman Brothers päästmine ebaõnnestus ning pank palus kohtult pankrotikaitset. Endine USA keskpanga juht Alan Greenspan ennustab veel mitme suur finantsasutuse pankrotti. Vt. samas: Lehman Brothers; Miks aktsiaturud langevad? Diagramm: USA finantskriisi järgmised ohvrid; Virge Lahe. USA finantskriis kergitab laenu hinda ka Eesti pankades

The Boston Marathon Bombers: the Lethal Cocktail that Turned Troubled Youth to Terrorism

Directory of Open Access Journals (Sweden)

Anne Speckhard

2013-06-01

Full Text Available The Tsarnaev brothers came from the war-torn Chechen diaspora and found asylum in the United States. The elder brother,Tamerlan, carried actual memories of fleeing from the 1994-96 Chechen war. He also lived in Dagestan for a year at the time when the Chechen warlord Basayev was engaging in a campaign of more than thirty suicide attacks, including mass hostage takings. When Tamerlan made it to the United States, he tried to assimilate but failed to make it. The family struggled hard to make a living in the U.S.; but in the end the parents divorced and the father returned to Dagestan. Dzhokhar, the younger brother, made it into an American university but Tamerlan did not succeed in higher education, trying to pursue a boxing career instead. When his immigration status precluded a boxing career, he became disillusioned. Meanwhile his mother, concerned about his descent into smoking marijuana and drinking alcohol, arranged an Islamic tutor for him. The ingredients for the lethal cocktail of terrorism came together when Tamerlan's individual vulnerabilities made him seek online contacts via the Internet and brought him in touch with offline mentors, militants and extremists who glorified Al-Qaeda’s global jihad. Through these channels he became receptive to the terrorist ideology, found a jihadist group with global reach to align with, received technical instructions from the Inspire magazine and found enough support for executing the Boston marathon attack, pulling his younger brother along and dying in the process as he had expected.

Familial cases of Norrie disease detected by copy number analysis.

Science.gov (United States)

Arai, Eisuke; Fujimaki, Takuro; Yanagawa, Ai; Fujiki, Keiko; Yokoyama, Toshiyuki; Okumura, Akihisa; Shimizu, Toshiaki; Murakami, Akira

2014-09-01

Norrie disease (ND, MIM#310600) is an X-linked disorder characterized by severe vitreoretinal dysplasia at birth. We report the results of causative NDP gene analysis in three male siblings with Norrie disease and describe the associated phenotypes. Three brothers with suspected Norrie disease and their mother presented for clinical examination. After obtaining informed consent, DNA was extracted from the peripheral blood of the proband, one of his brothers and his unaffected mother. Exons 1-3 of the NDP gene were amplified by polymerase chain reaction (PCR), and direct sequencing was performed. Multiplex ligation-dependent probe amplification (MLPA) was also performed to search for copy number variants in the NDP gene. The clinical findings of the three brothers included no light perception, corneal opacity, shallow anterior chamber, leukocoria, total retinal detachment and mental retardation. Exon 2 of the NDP gene was not amplified in the proband and one brother, even when the PCR primers for exon 2 were changed, whereas the other two exons showed no mutations by direct sequencing. MLPA analysis showed deletion of exon 2 of the NDP gene in the proband and one brother, while there was only one copy of exon 2 in the mother. Norrie disease was diagnosed in three patients from a Japanese family by clinical examination and was confirmed by genetic analysis. To localize the defect, confirmation of copy number variation by the MLPA method was useful in the present study.

Sibship Size and Gendered Resource Dilution in Different Societal Contexts.

Directory of Open Access Journals (Sweden)

Matthijs Kalmijn

Full Text Available Resource dilution theory hypothesizes that children's educational attainment suffers from being raised with many siblings, as the parental resources have to be shared with more children. Based on economic and cultural theories, we hypothesize that resource dilution is gendered: especially a larger number of brothers is harmful to a person's educational attainment. Using the Survey of Health, Ageing and Retirement in Europe, covering 18 European countries, we show that the number of brothers is more negatively related with the odds of obtaining a college degree than the number of sisters. This holds particularly for women. However, this pattern is weaker in countries that are known to have a more gender-egalitarian climate.

Little Brother Joins the Large Family

Science.gov (United States)

2006-12-01

On the night of 15 December 2006, the fourth and last-to-be-installed VLTI Auxiliary Telescope (AT4) obtained its 'First Light'. The first images demonstrate that AT4 will be able to deliver the excellent image quality already delivered by the first three ATs. It will soon join its siblings to perform routinely interferometric measurements. ESO PR Photo 51a/06 ESO PR Photo 51a/06 VLT Auxiliary Telescope The VLT is composed of four 8.2-m Unit Telescope (Antu, Kueyen, Melipal and Yepun). They have been progressively put into service together with a vast suite of the most advanced astronomical instruments and are operated every night in the year. Contrary to other large astronomical telescopes, the VLT was designed from the beginning with the use of interferometry as a major goal. The VLT Interferometer (VLTI) combines starlight captured by two or three 8.2- VLT Unit Telescopes, dramatically increasing the spatial resolution and showing fine details of a large variety of celestial objects. ESO PR Photo 51b/06 ESO PR Photo 51b/06 One AT Under the Sky However, most of the time the large telescopes are used for other research purposes. They are therefore only available for interferometric observations during a limited number of nights every year. Thus, in order to exploit the VLTI each night and to achieve the full potential of this unique setup, some other (smaller), dedicated telescopes were included into the overall VLT concept. These telescopes, known as the VLTI Auxiliary Telescopes (ATs), are mounted on tracks and can be placed at precisely defined "parking" observing positions on the observatory platform. From these positions, their light beams are fed into the same common focal point via a complex system of reflecting mirrors mounted in an underground system of tunnels. The Auxiliary Telescopes are real technological jewels. They are placed in ultra-compact enclosures, complete with all necessary electronics, an air conditioning system and cooling liquid for

That's Not Montessori

Science.gov (United States)

Peters, Dane L.

2009-01-01

The author could not contain herself one day at school recently when a parent of three children shared something she had heard from her eldest daughter. That morning, the eldest daughter was grumbling about the fact that she and her Lower Elementary brother had to go to school while her Preschool brother did not, and she announced to her mother,…

Your Radiologist Explains Nuclear Medicine

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Full Text Available ... Recently posted: How to Obtain and Share Your Medical Images Movement Disorders Video: The Basketball Game: An ... oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk Grove Village, Illinois. I’d ...

Your Radiologist Explains Nuclear Medicine

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Full Text Available ... Site Index A-Z Spotlight Recently posted: Pancreatic Cancer The Limitations of Online Dose Calculators Video: The ... Dr. Ramji Rajendran, a radiation oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk ...

Your Radiologist Explains Nuclear Medicine

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Full Text Available ... June is Men's Health Month Recently posted: Pancreatic Cancer The Limitations of Online Dose Calculators Video: The ... Dr. Ramji Rajendran, a radiation oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk ...

The impact of childhood sickness on adult socioeconomic outcomes: Evidence from late 19th century America

Science.gov (United States)

Warren, John Robert; Knies, Laurie; Haas, Steven; Hernandez, Elaine M.

2013-01-01

We use family fixed-effects models to estimate the impact of childhood health on adult literacy, labor force outcomes, and marital status among pairs of white brothers observed as children in the 1880 U.S. Census and then as adults in the 1900–1930 Censuses. Given our focus on the 19th century, we observed a wider array of infectious, chronic, and traumatic health problems than is observed using data that are more recent; our results thus provide some insights into circumstances in modern developing countries where similar health problems are more frequently observed. Compared to their healthy siblings, sick brothers were less likely to be located (and thus more likely to be dead) 20–50 years after their 1880 enumeration. Sick brothers were also less likely to be literate, to have ever been married, and to have reported an occupation. However, among those with occupations, sick and healthy brothers tended to do similar kinds of work. We discuss the implications of our results for research on the impact of childhood health on socioeconomic outcomes in developed and developing countries. PMID:22809795

Mexican-American Adolescents' Gender-Typed Characteristics: The Role of Sibling and Friend Characteristics.

Science.gov (United States)

Perez-Brena, Norma J; Wheeler, Lorey A; Updegraff, Kimberly A; Schaefer, David R

2015-07-01

This study examined the role of sibling and friend characteristics in Mexican-American youth's gender-typed characteristics (i.e., attitudes, interests, and leisure activities) in early versus middle adolescence using a sibling design. Mexican-American 7th graders (M = 12.51 years; SD = .58) and their older siblings (M = 15.48 years; SD = 1.57) from 246 families participated in home interviews and a series of seven nightly phone calls. Results revealed that younger/early adolescent siblings reported more traditional gender role attitudes than their older/middle adolescent siblings and older brothers were more traditional in their attitudes than older sisters. When comparing siblings' gender-typed interests and leisure activities, boys reported more masculine orientations than girls and girls reported more feminine orientations than boys. Older brothers' gender-typed characteristics were associated with the amount of time spent with and gender characteristics of their friendship group, but for younger brothers, sibling characteristics were associated with their gender-typed characteristics. In contrast, both sibling and friendship characteristics were significantly associated with older and younger sisters' gender-typed characteristics. The discussion addressed the different correlates of older and younger sisters' and brothers' gender-typed characteristics.

Parkinson's Disease Videos

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Full Text Available ... library Topic Type Living Alone: Home Safety and Management in PD Expert Briefings: Marijuana and PD: What ... a Brother: Donna’s Story OHSU - Parkinson's Disease: Pharmacological Management of Depression, Anxiety & Psychosis What Are Some Strategies ...

Birth Order and Sibling Sex Ratio in a Population with High Fertility: Are Turkish Male to Female Transsexuals Different?

Science.gov (United States)

Bozkurt, Ali; Bozkurt, Ozlem Hekim; Sonmez, Ipek

2015-07-01

Western studies have consistently found that androphilic (sexually attracted to men) male-to-female transsexuals have a later birth order and a relative excess of brothers compared with appropriate control participants. However, non-Western studies on birth order and sibling sex ratio in androphilic males (transsexual or non-transsexual) are rare. The objective of the study was to test the hypothesis that androphilic male-to-female transsexuals have a late birth order and a relative excess of brothers in a non-Western culture with a higher fertility rate. The participants were 60 androphilic male-to-female transsexuals and 61 male heterosexual controls. The transsexual participants had significantly more older brothers than the control participants, but the groups did not differ in their numbers of older sisters, younger brothers, or younger sisters. The foregoing pattern is usually referred to as the "fraternal birth order effect." Slater's and Berglin's Indexes both showed that the mean birth order of the control participants was very close to that expected from a random sample drawn from a demographically stable population whereas the mean birth order of the transsexual participants was later. A measure of sibship composition, brothers/all siblings, showed that the transsexual group had a higher proportion of male siblings compared with the control group. In conclusion, the present study found that Turkish androphilic male-to-female transsexuals show the same high fraternal birth order that has been found in comparable androphilic samples in Western Europe, North America, and the South Pacific, which suggests a common underlying biological causal mechanism.

WORKPLACE SURVEILLANCE: BIG BROTHER IS WATCHING YOU?

Directory of Open Access Journals (Sweden)

Corneliu BÎRSAN

2018-05-01

Full Text Available Only recently workplace surveillance has become a real concern of the international community. Very often we hear about employers who monitor and record the actions of their employees, in order to check for any breaches of company policies or procedures, to ensure that appropriate behaviour standards are being met and that company property, confidential information and intellectual property is not being damaged. Surveillance at workplace may include inter alia monitoring of telephone and internet use, opening of personal files stored on a professional computer, video surveillance. But what if this monitoring or recording breaches human rights? In order to give practical examples for these means, we shall proceed to a chronological analysis of the most relevant cases dealt by the European Court of Human Rights along the time, in which the Strasbourg judges decided that the measures taken by the employers exceed the limits given by Article 8 of the Convention. After providing the most relevant examples from the Court’s case-law in this field, we shall analyse the outcome of the recent Grand Chamber Barbulescu v. Romania judgment. The purpose of this study is to offer to the interested legal professionals and to the domestic authorities of the Member States the information in order to adequately protect the right of each individual to respect for his or her private life and correspondence under the European Convention on Human Rights.

Psicosis inducida ("foliex a deux" e intoxicación crónica por plomo.: Reporte de un caso y discusión.

Directory of Open Access Journals (Sweden)

Jaime Arias

1996-04-01

Full Text Available We report a case of two brothers suffering the same paranoia psychosis. The older one presented an altered consciousness and needed hospitalization. During hospitalization, he was considered as having lead chronic intoxication. The lead serum level was 65 ug/dl (N:<30 ug/dl and the lead hair was 25 pg/gr-tiss (N:<10 pg/gr-tiss. He also presented clinically with encephalopathy, disorder of the autonomic dysfunction. He leaded his body for eleven years because of delutional ideas, and induced these ideas and behavior to his brother (folie a deux. The coincidence between these disorders in extremely rare so we believe this case report is of clinical interesting. (Rev Med Hered 1996; 7: 101-104.

Visual hallucinations caused by Charles Bonnet Syndrome: A case ...

African Journals Online (AJOL)

had no cognitive impairment and was fully aware of the ... eration. Ms P's main complaint was visual hallucinations. ... brother in front of her eyes. She also displayed ... her would seem to develop a full beard. .... Beta blocking agents. 4.

Parkinson's Disease Videos

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Who is my brother's keeper?

Science.gov (United States)

Kottow, M H

2002-02-01

Clinical and research practices designed by developed countries are often implemented in host nations of the Third World. In recent years, a number of papers have presented a diversity of arguments to justify these practices which include the defence of research with placebos even though best proven treatments exist; the distribution of drugs unapproved in their country of origin; withholding of existing therapy in order to observe the natural course of infection and disease; redefinition of equipoise to a more bland version, and denial of post-trial benefits to research subjects. These practices have all been prohibited in developed, sponsoring countries, even though they invariably have pockets of poverty where conditions comparable to the Third World prevail. Furthermore, the latest update of the Declaration of Helsinki clearly decries double ethical standards in research protocols. Under these circumstances, it does not seem appropriate that First World scholars should propose and defend research and clinical practices with less stringent ethical standards than those mandatory in their own countries. Recent years have witnessed frequent reports of less stringent ethical standards being applied to both clinical and research medical practices, for the most part in the field of drug trials and drug marketing, initiated by developed countries in poorer nations. Still more unsettling, a number of articles have endorsed the policy of employing ethical norms in these host countries, which would be unacceptable to both the legislations and the moral standards of the sponsor nations. Also, these reformulations often contravene the Declaration of Helsinki or one of its updates. This paper is not so much concerned with the actual practices, which have been subjected to frequent scrutiny and publicly decried when gross misconduct occurred. Rather, my concern relates to the approval and support such practices have found in the literature on bioethics from authors who might be expected to use their energy and scholarship to explore and endorse the universalisability of ethics rather than to develop ad hoc arguments that would allow exceptions and variations from accepted moral standards. To this purpose, issue will be taken with arguments in three fields: medical and pharmaceutical practices, research strategies, and local application of research results.

Association between pregnancy losses in women and risk of atherosclerotic disease in their relatives

DEFF Research Database (Denmark)

Ranthe, Mattis Flyvholm; Diaz, Lars Jorge; Behrens, Ida

2016-01-01

) and the atherosclerotic endpoint (brothers). Parents whose daughters had stillbirths had 1.14 (95% CI 1.05-1.24) and 1.07 (95% CI 0.96-1.18) times the rates of MI and CVI, respectively, as parents whose daughters had no stillbirths. CONCLUSION: Certain pregnancy losses and atherosclerotic diseases in both heart and brain......AIMS: A common underlying mechanism with a genetic component could link pregnancy losses with vascular disease. We examined whether pregnancy losses (miscarriages and stillbirths) and atherosclerotic outcomes co-aggregated in families. METHODS AND RESULTS: Using Danish registers, we identified...... women with pregnancies in 1977-2008, and their parents (>1 million) and brothers (>435 000). We followed parents for incident ischaemic heart disease (IHD), myocardial infarction (MI), and cerebrovascular infarction (CVI), and brothers for a broader combined atherosclerotic endpoint. Using Cox...

Parkinson's Disease Videos

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United States Security Policy Implications of a Post-Fidel Cuba

Science.gov (United States)

2012-03-10

paternalism .8 Even Cuba’s first president was complicit when he negotiated a perpetual lease for Guantanamo Naval 4 Base that made a sham of...diplomatic alliances, and even the health of Fidel Castro. Most recently, the succession of the authoritarian dictatorship from brother to brother...controlled within an authoritarian regime. 26 Undoubtedly, Raúl Castro appreciates the benefits of a model of “patrimonial authoritarianism , or economic

Possible X linked congenital mitochondrial cardiomyopathy in three families.

OpenAIRE

Orstavik, K H; Skjörten, F; Hellebostad, M; Hågå, P; Langslet, A

1993-01-01

Familial cases of childhood congestive cardiomyopathy with X linked recessive inheritance and abnormalities of heart muscle mitochondria have been previously reported. We report here three families with possible X linked congestive cardiomyopathy and specific mitochondrial abnormalities. The heart disorder presented as endocardial fibroelastosis with neonatal death in two brothers in one family, and as heart failure and death in infancy in two brothers in the other two families. In one family...

Familial Discoid Medial Meniscus Tear in Three Members of a Family: A Case Report and Review of Literature

OpenAIRE

Ahmed Ali, Raheel; McKay, Scott

2014-01-01

Background. A discoid meniscus is a thickened variant of the normal C-shaped meniscus prone to injury. Discoid medial meniscal tears have rarely been reported within families and may suggest familial or developmental origins. Methods. We report the cases of two Caucasian brothers with symptomatic discoid medial meniscus tears. A literature review was conducted addressing discoid medial meniscus and cases of familial meniscus tears. Case Presentation. Physically active brothers presented with ...

Birth order, sibling sex ratio, handedness, and sexual orientation of male and female participants in a BBC internet research project.

Science.gov (United States)

Blanchard, Ray; Lippa, Richard A

2007-04-01

This study investigated the relations among sexual orientation, fraternal birth order (number of older brothers), and hand-preference. The participants were 87,798 men and 71,981 women who took part in a Web-based research project sponsored by the British Broadcasting Corporation (BBC). The results yielded some evidence confirming prior findings that non-right-handedness is associated with homosexuality in men and women, that older brothers increase the odds of homosexuality in men, and that the effect of older brothers on sexual orientation is limited to right-handed men. The evidence was weaker than in previous studies, however, probably because the usual relations among the variables of interest were partially obscured by the effects of other factors. Thus, the homosexual men and women had higher rates of non-right-handedness than their heterosexual counterparts, but the strongest handedness finding for both sexes was a marked tendency for participants who described themselves as ambidextrous also to describe themselves as bisexual. The birth order data were strongly affected by a tendency for the male participants to report an excess of older sisters, and the female participants to report an excess of older brothers. Statistical analyses confirmed that this was an artifact of the parental stopping rule, "Continue having children until you have offspring of both sexes." In subsequent analyses, participants were divided into those who did and did not have younger siblings, on the grounds that the data of the former would be less contaminated by the stopping rule. In the former subsample, the right-handed homo/bisexual males showed the typical high ratio of older brothers to older sisters, whereas the non-right-handed homo/bisexual males did not.

Apparent X-linked primary ciliary dyskinesia associated with retinitis pigmentosa and a hearing loss.

Science.gov (United States)

Krawczyński, Maciej R; Dmeńska, Hanna; Witt, Michał

2004-01-01

Three brothers, one 10-year-old and a pair of 14-year-old dizygotic twins--expressed the classical, early-onset retinitis pigmentosa (RP) with typical ophthalmoscopic findings, night blindness, visual field constricted to 10 degrees and flat ERG response. All three brothers were also diagnosed with primary ciliary dyskinesia (PCD) and had recurrent respiratory infections, chronic sinusitis and bronchiectasis. In all of them, resection of the middle lobe of the right lung was performed. A similar clinical picture of coexisting RP and PCD was noted in the brother of the probands' mother. All probands displayed situs solitus. Consistent with the X-linked mode of RP inheritance, there were also three obligatory female carriers of the disorder in this family: the mother of the affected boys, her mother and a daughter of her brother. In all of them, retinitis pigmentosa "sine pigmento" was found with milder but clinically significant symptoms (mild night blindness, visual field constricted to 30 degrees, and scotopic and photopic ERG responses reduced to 30-60%). No extraocular symptoms were detected in any of the heterozygous female carriers. This family presents an example of two rare phenomena: X-linked dominant retinitis pigmentosa (with milder expression in females) and a rare combination of RP with recurrent respiratory infections due to PCD.

Parkinson's Disease Videos

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Full Text Available ... Memorial Medicinal: “Terapia fisica para el Parkinson” CareMAP: Thinking Changes: Part 2 Why Dance for PD? CareMAP: ... a Father and a Brother: Donna’s Story CareMAP: Thinking Changes: Part 1 Aware in Care: Real Stories ...

Novel about Artist: Postmodern Variations (Instantiated by Novels “The Tin Drum” by Günter Grass, “Brother of Sleep” by Robert Schneider, “Perfume: The Story of a Murderer” by Patrick Süskind

Directory of Open Access Journals (Sweden)

Sofiya Varetska

2013-12-01

Full Text Available An attempt to show the modification of classic novel about an artist (Künstlerroman through a prism of postmodernism instantiated by German novels of the second half of the twentieth century “The Tin Drum”, “Brother of Sleep”, “Perfume: The Story of a Murderer” was accomplished. Crisis of artistic apperception in the twentieth century is demonstrated. Different conceptions of the creative process of main characters are compared. The main attention was focused on the clash between man and artist, life and art, daily routine and spirituality. In the postmodern age the cynical worldview model is predominating. At the same time tales, where magic and reality, sentimentality and brutality are combined, enjoy widespread popularity. An art of genius has positive connotations in general, but some of chosen novels are revealing the reverse side of the coin, when the art is capable to create an evil in its superior manifestations. For a wonder a presence of negative, monstrosity and disgust attract attention of the crowd rather than beauty. Therefore tin the article new idea that talent is on the verge of monstrosity is asserted. These two concepts exist together rely on each other. Every hero is like two-faced Janus to some extent. On the one hand, being endowed with Divine Grace he has a talent, but on the other hand, having something demoniacal is possessed by physical defect. On the one hand, they limelight and fire our imagination by their unusualness, on the other hand, they push away by their monstrosity and disgust. Main characters are always teetering on the edge. However the notion of edge is taking the wider meaning in the contemporary society. Consequently, having used all features of classic novel about an artist and portrayed them through a prism of modern perception of the world, writers created a new compilation – postmodern novel about an artist.

The 48, XXXX/49,XXXXY/49,XXXX,i(Yq) mosaicism in a 3-year-old boy from a twin pregnancy.

Science.gov (United States)

Kaluzewski, B; Podkul, D; Zaborowska, I; Moruzgala, T; Jakubowski, L

1977-07-26

A 3-year-old boy from twin pregnancy with the features of marked dystrophia from birth, deficient growth, considerable retardation of physical and mental development, numerous somatic defects, suspected congenital heart disease, and hypoplastic external genitalia, is reported. The 48,XXXX/49,XXXXY/49,XXXX,i(Yq) karyotype was diagnosed. The boy's brother, normally developed, had a 46,XY karyotype. It was found on the basis of serologic findings that the brothers were dizygotic twins.

Siblings of Adults with Intellectual Disabilities: Their Perspectives On Guardianship and Its Alternatives

OpenAIRE

Brady, Anna M.

2017-01-01

Adult siblings of people with intellectual and developmental disabilities (IDD) are often on the front lines of supporting their brothers and sisters with IDD through caregiving and guardianship roles after their parents pass away. However, these siblings are often uninformed or under informed about ways that they can support their brothers and sisters. This study had the following three purposes: to determine what adult siblings of adults with IDD know about guardianship and its alternatives...

The 16th International Twin Congress: Highlights from Madrid/Twin Research: Twin Study of Partner Aggression; ABO Incompatibility in Dizygotic Twins; Growth Discordance in a Monoamniotic Twin Pair; Quick Note on Twin Implantation/In the Media: Long-Lost Twins Found; NASA Twin Experiment; Twin Brothers and the Las Vegas Attack; Retired Twin Airline Pilots; Twin Film Clips.

Science.gov (United States)

Segal, Nancy L

2018-02-01

Highlights from the 16th International Twin Congress, held in Madrid, Spain from November 16-18, 2017, are presented. The Twin Congress, formerly held every three years, now takes place biennially with a single-day meeting organized during the off years. This meeting is the largest gathering of scientific twin researchers, medical personnel, and representatives of multiple birth organizations in the world. This overview is followed by reviews of recent twin research and commentary concerning partner aggression, ABO incompatibility in dizygotic twins, growth discordance in a monoamniotic twin pair and twin implantation. The article closes with summaries of timely topics in the media, namely a father's finding of his long-lost twin children, early results from the NASA twin experiment, twin brothers at the center of the October 2017 Las Vegas attack, retired twin airline pilots, and clips from recent films with twin-based themes.

The roles of adult siblings in the lives of people with severe intellectual and developmental disabilities.

Science.gov (United States)

Hall, Sarah A; Rossetti, Zach

2018-05-01

Siblings of people with intellectual and developmental disabilities (IDD) often assume key roles to support their brothers and sisters. For people with more significant support needs, siblings may undertake additional roles and responsibilities throughout their lives. The purpose of the present study was to identify and describe the roles of adult siblings who have a brother or sister with severe IDD. Seventy-nine adult siblings from 19 to 72 years of age completed an online survey with open-ended questions about the roles they play in their relationships with their brother or sister. Thematic analysis resulted in identification of several roles including caregiver, friend (social partner), advocate, legal representative, sibling (teacher/role model), leisure planner and informal service coordinator. Siblings assume key roles in the lives of people with IDD and need support from family and professionals to perform these roles. © 2017 John Wiley & Sons Ltd.

Case report of Ellis-Van Creveld syndrome

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Baghdadi T

2001-09-01

Full Text Available Ellis-van Creveld sydrome (Chondroectodermal dysplasia is a hereditary form of short limb disproportionate dwarfism characterized by diffuse involvement of skeletal system and visceral organs. Two brothers affected by this syndrome are presented here following a brief account of the disease's manifestations.

The political parties and significant personalities of the Bessarabian Zemstvo (1869-1917

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Valentin Tomuleţ

2017-12-01

Full Text Available This article focuses on some parties and significant personalities who worked in the Bessarabian institution of local self-government – Zemstvo (created in 1869 and contributed to the development of the province. The authors found that some nobles united and formed political parties. Parties of the Zemstvo were groups of persons related to the most influential families from Bessarabia. For some of them the Zemstvo served as a platform on which the nobles could solve their problems. It can be said that the Zemstvo was the “alter ego” of the Bessarabian nobility. As a result, in the political life of Bessarabia two main parties were formed – “Young Bessarabia” (“Molodaya Bessarabiya” and “Old Greek Party” (Starogrecheskaya”, which succeeded each other at the helm of power. In the early 1880s, the “Old Greek party” finally defeated its rival and gained full power in the Bessarabian Zemstvo administration. Counselors saw in the Bessarabian Zemstvo an important and reliable instrument for committing abuses. For example, the Head of the Orhei Zemstvo Council Cozac embezzled money from the Zemstvo budget. When the fact of the theft was uncovered, and this was written about in the press, Cozac shot himself. Each group of the nobles included not only people related to certain interest in economic and political life of Bessarabia, but also people related by kinship, acting in the family interests. In 1881-1884, 18 of the 52 provincial councelors were relatives: brothers Semigradov (4 people, brothers Krupensky, brothers Sinadino, brothers Dunca, brothers Cotruta (2 people. The Krupensky family was the most influential family in the Bessarabian Zemstvo. The publicist P. Krushevan wrote in this regard that the Krupensky clan usurped all the power in Bessarabia, and the Governor S. Urusov noted their importance in economic and political life of the province. Many members of the Zemstvo left their mark in the economic, political, and

Analysis of Student Understanding of Basic AC Concepts

Science.gov (United States)

1998-12-10

flexible but pedagogically sound structure, multiple methods of instruction, and a single gathering of "at the ready" resources. There are two questions...bulb. His curious kid brother Sam comes along and takes the circuit apart. While putting it back, he adds a second 3 ohm resistor in parallel to the...first. Do you think this will make the light bulb in the kid brother’s circuit brighter, dimmer, or the same as Sam’s? Explain. (6) Without changing

AHP 44: DPAL RGYAL: ARTIST AND PHOTOGRAPHER

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Klu thar rgyal ཀླུ་ཐར་རྒྱལ།

2017-02-01

Full Text Available One sweltering summer afternoon in 2016, my family was enjoying yogurt while sitting in order of age around a table at my home. Father suddenly clapped his leg and blurted out "Oh! I remember!" took his cell phone from his coat pocket and said, "Klu kho, please translate these new Chinese messages for me." "China Mobile is really your best friend! It texts you almost every day!" I joked, taking the phone from his hand. One message was for my older brother, Dpal rgyal. The prefecture government informed Brother (b. 1980 that he was chosen to represent Mtsho lho (Hainan Tibetan Autonomous Prefecture for the 2016 Mtsho sngon (Qinghai Province Disabled Persons vocational skills competition in the photography category. Photography contestants were required to bring their own camera and would take photographs at the competition venue. ...

Cine-Club

CERN Document Server

Ciné-Club

2012-01-01

Projection from DVD – entrance 2 CHF for info http://cern.ch/Cineclub/ Thursday 12 July 2012 at 20:00 CERN Council Chamber The Darjeeling Limited By Wes Anderson (USA, 2007) With: Owen Wilson, Adrien Brody and Jason Schwartzmann Original version English; French subtitles; 91 minutes A year after the accidental death of their father, three drug-addicted brothers – each suffering from depression – meet for a train trip across India. Francis, the eldest, has organized it. The brothers argue, sulk, resent each other, and fight. The youngest, Jack, estranged from his girlfriend, is attracted to one of the train's attendants. Peter has left his pregnant wife at home, and he buys a venomous snake. After a few days, Francis discloses their surprising and disconcerting destination. Amid foreign surroundings, can the brothers sort out their differences? A funeral, a meditation, a hilltop ritual, and the Bengal Lancer figure in the reconciliation. * * * * * Thursday 19 J...

Rate of Family Violence Among Patients With Schizophrenia in Japan.

Science.gov (United States)

Kageyama, Masako; Yokoyama, Keiko; Nagata, Satoko; Kita, Sachiko; Nakamura, Yukako; Kobayashi, Sayaka; Solomon, Phyllis

2015-09-01

Family violence is a serious concern in the era of deinstitutionalization in Japan. Consequently, we aimed to clarify the rate of family violence among patients with schizophrenia, and differences by sex and relationship to the patient. We asked households belonging to a family group association to complete a self-administered mail survey. Of 350 households that responded, data for 302 were analyzed. The rate of violence toward any family member was 60.9% over the lifetime and 27.2% in the past year. Order of lifetime rates for family members from highest to lowest was 51.0% for mothers, 47.0% for fathers, 30.7% for younger sisters, 23.8% for spouses, 19.5% for younger brothers, 18.2% for older sisters, 17.1% for older brothers, and none for children. Younger sisters were more likely to be victims compared to other siblings. Fathers and older brothers were likely to be victims when patients were male. © 2015 APJPH.

[Panhypopituitarism in one identical twin: the effect of hormone replacement].

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Del Canho, Harrij; van Alfen-van der Velden, Janiëlle; del Canho, Riwka; Otten, Barto

2011-01-01

Panhypopituitarism in childhood is rare. It is even rarer if the disorder appears in a boy with an identical but healthy twin brother. In such a patient it is useful to study the consequences of the hormone disorder and the effect of hormone replacement. A 6-year-old boy saw a paediatrician because of short stature. He was much shorter than his identical twin brother and he had more abdominal fat mass and a smaller penis. Laboratory tests identified hypothyroidism of central origin, in combination with hypocortisolism and growth hormone deficiency. Hormonal replacement resulted in an improvement in growth rate. At the age of 15 years, testosterone therapy was introduced because puberty had not occurred and his growth rate was low. Finally the patient grew a few centimetres taller than his twin brother. In the first year of life, panhypopituitarism has no negative consequences for growth. After this point, growth is clearly delayed. With sufficient replacement growth can completely catch up.

'Recognized, Valued and Supported'? The Experiences of Adult Siblings of People with Autism Plus Learning Disability.

Science.gov (United States)

Tozer, Rosemary; Atkin, Karl

2015-07-01

The potential of adult siblings to offer long-term support to a brother or sister with autism is rarely realized. To understand this, our study explores the expectations of social care among adult siblings. Using qualitative interviews, we spoke to 21 adult siblings about their family relationships and engagement with service delivery, met with 12 of their siblings with autism and talked to 12 social care staff. Siblings, although reflecting on the difficulties of growing up with someone who had autism, expressed a commitment towards their brother or sister. Most wanted involvement in their care. While some siblings described positive relationships with services, many felt marginalized. Practitioners largely confirmed their perceptions, while offering a justification for why they struggled to engage with adult siblings. By understanding the way relationships between siblings change over time, adult siblings' contribution to the lives of their disabled brother or sister can be better supported. © 2015 John Wiley & Sons Ltd.

قاعـدة "الفنـاء في الإخـوان" في فكر بديـع الزمـان - Dr. Farhad Ibrahim Akbar al-Shawani: The rule of self forgetfulness for the sake of brothers according to the thought of Bediuzzaman

OpenAIRE

الشواني, د. فرهاد إبراهيم أكبر

2015-01-01

قاعـدة قاعـدة "الفنـاء في الإخـوان" في فكر بديـع الزمـان-دراسة تأصيلية مقاصدية للوحدة الإسلامية- -ABSTRACT- The rule of self forgetfulness for the sake of brothers according to the thought of Bediuzzaman Dr. Farhad Ibrahim Akbar al-Shawani This study explores an important rule which was linked to its sources from the spirit of the holy Quran and the prophetic tradition by Ustadh Nursi. It states that a person should experience self forgetfulness for the sake of his community. An ind...

[Genetic and environmental contribution to rheumatoid arthritis: a family study].

Science.gov (United States)

Iebba, Filippo; Di Sora, Fiorella; Leti, Wilma; Montella, Tatiana; Montella, Francesco

2012-01-01

We report on the HLA typing of three brothers (A, B, C) with rheumatoid arthritis (RA) and their six sons. This family is interesting for the full concordance for RA between parents. The aim of this study was the discovery of genetic and/or enviromental cofactors determining this absolute concordance.

Interdisciplinary Full Mouth Rehabilitation of a Patient with Amelogenesis Imperfecta: A Case Report with 8 Years Follow-up

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Sreedevi, S; Sanjeev, R; Ephraim, Rena; Joseph, Mathai

2014-01-01

This case report deals with the interdisciplinary approach of a 28-year-old lady with Amelogenesis imperfecta of the hypoplastic kind. The patient came with a chief illness of worn out teeth, unsatisfactory esthetics and severe sensitivity of teeth. Her family history revealed a related situation in her father’s brother and her sister. On clinical assessment, the crowns of all teeth were worn out. The plan of the treatment was to protect as much tooth structure, restore the vertical dimension, and improve esthetics and masticatory function. The treatment procedures involved prosthodontic, endodontic, and periodontic interventions. After recording the vertical height, endodontic treatment and crown lengthening were performed with respect to the lower anteriors. The lost vertical height was regained in stages by insertion of full coverage crowns for all the teeth. The patient’s esthetic and functional needs were met with systematic and sequential interdisciplinary treatment approach. PMID:25628493

HALF-BROTHERS IN THE SCHULHOF FAMILY?

International Nuclear Information System (INIS)

Vokrouhlicky, David; Nesvorny, David

2011-01-01

Disruptive collisions in the asteroid belt produced groups of fragments known as the asteroid families. The studies of identified asteroid families help us to better understand issues related to impact physics, space weathering, asteroid interior, and collisional evolution of the main belt. Here, we analyze a family near the central main belt asteroid (2384) Schulhof. We show that the previously found group of objects around (81337) 2000 GP36 is actually a sub-cluster in the larger Schulhof family. Using backward integrations we demonstrate that the orbits of sub-cluster asteroids converge to that of (2384) Schulhof at 780 ± 100 kyr ago, suggesting that the breakup event happened very recently. Interestingly, a similar analysis of the two newly discovered members of the Schulhof family may indicate a second event ∼< 100 kyr ago (e.g., secondary collision, fission, satellite instability). If confirmed, the formation history of the Schulhof family would suggest that small asteroids may have very colorful lifetimes. Additional astrometric observations of the two new member asteroids will be needed to improve their present orbit and better constrain their past histories.

Religion and gender in a men's hospital and school of nursing, 1866-1969.

Science.gov (United States)

Wall, Barbra Mann

2009-01-01

This article explores religious beliefs, practices, and representations of the Alexian Brothers, a religious order of Catholic nursing brothers, and the role of gender in this discourse. Nursing in the United States developed within a cultural framework of caring as part of women's roles in families and communities. Yet, a study of the Alexian Brothers challenges the dominance of the "female" in most gender analyses of nursing. Historical methodology is used to evaluate and interpret data within the broader framework of historiographical literature on gender, religion, and nursing. In analyzing nursing, religion, and gender, attention has been paid to representations, mainly of women, through photographs and written literature. In this article, the same sources are used for men. The story of the Alexian Brothers and the men they educated is a testament to the power of gender and religion in nursing history. These men carved out a system of caring that recognized it as a responsibility not only of women but also of men. As they asserted that their paid work was a Christian calling, they renegotiated dominant notions of masculinity. In doing so, male nurses navigated among an array of representations, from nurse, to school administrator, to military soldier, to religious person, to professional practitioner of scientific medicine. These self-representations in the masculine spaces of the hospital and nursing school were designed to debunk stereotypes of feminine men, and they challenged traditional spatial boundaries.

Continuity, commitment and context: adult siblings of people with autism plus learning disability.

Science.gov (United States)

Tozer, Rosemary; Atkin, Karl; Wenham, Aniela

2013-09-01

Sibling relationships are usually lifelong and reciprocal. They can assume particular significance when a brother or sister has a learning disability. Until recently, adult siblings of people with disabilities such as severe autism have been ignored by policy, practice and research. This qualitative study contributes to an emerging literature by exploring how adult siblings, who have a brother or sister with autism (plus learning disability) and living in England, give meaning to their family (and caring) relationships and engage with service delivery. We spoke to 21 adult siblings using semi-structured interviews and met with 12 of their siblings with autism. Our analysis, using a broad narrative approach, demonstrates the continuity of the sibling relationship and an enduring personalised commitment. The nature of this relationship, however, is sensitive to context. How non-disabled adult siblings relate to their childhood experience is fundamental when making sense of this, as is their need to fulfil other social and family obligations, alongside their 'sense of duty' to support their disabled brother or sister. Sibling experience was further mediated by negotiating their 'perceived invisibility' in social care policy and practice. Our work concludes that by understanding the way relationships between siblings have developed over time, adult siblings' contribution to the lives of their brother or sister with autism can be better supported for the benefit of both parties. Such an approach would support current policy developments. © 2013 John Wiley & Sons Ltd.

Religion and Gender in a Men’s Hospital and School of Nursing, 1866–1969

Science.gov (United States)

Wall, Barbra Mann

2009-01-01

Objectives This article explores religious beliefs, practices, and representations of the Alexian Brothers, a religious order of Catholic nursing brothers, and the role of gender in this discourse. Background Nursing in the United States developed within a cultural framework of caring as part of women’s roles in families and communities. Yet, a study of the Alexian Brothers challenges the dominance of the “female” in most gender analyses of nursing. Methods Historical methodology is used to evaluate and interpret data within the broader framework of historiographical literature on gender, religion, and nursing. In analyzing nursing, religion, and gender, attention has been paid to representations, mainly of women, through photographs and written literature. In this article, the same sources are used for men. Results The story of the Alexian Brothers and the men they educated is a testament to the power of gender and religion in nursing history. These men carved out a system of caring that recognized it as a responsibility not only of women but also of men. As they asserted that their paid work was a Christian calling, they renegotiated dominant notions of masculinity. In doing so, male nurses navigated among an array of representations, from nurse, to school administrator, to military soldier, to religious person, to professional practitioner of scientific medicine. These self-representations in the masculine spaces of the hospital and nursing school were designed to debunk stereotypes of feminine men, and they challenged traditional spatial boundaries. PMID:19448519

About the composition and processing of precious metals from the Serbian medieval mines

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Kovačević-Kojić Desanka

2013-01-01

Full Text Available Account Books of the Caboga (Kabužić Brothers 1426-1433 (Squarço - Reminder, Diary and Ledger from the Historical Archive of Dubrovnik provide new evidence about the high degree of treatment and composition of precious metals from the Serbian medieval mines. First of all, that the residue, after the purification of unprocessed into fine silver, was copper. Even the price of this process is listed. In the Squarço, in two items in a receipt from 1430, there is previously unknown data about auriferous silver (argento di glama, the composition of which, besides gold, also included copper, and the precisely determined shares of these metals per litre. Apart from the Account Books of the Caboga (Kabužić Brothers, other written sources and hitherto geological explorations have provided no clues regarding the presence of copper in the auriferous silver mines.

Wealthy in Heart: Oral History of Life Before Fort A.P. Hill

Science.gov (United States)

2011-05-01

treat for us every day when we got home from school. And then my brothers and I—I loved to play ball—they did too. I played softball , and we would go...Carroms, baseball, softball . Carroms; it’s a board game. Oh, tennis—we had a—our father built us a tennis court. It was a clay court, but we did play...champions for four years. I pitched, and we never lost a game. Softball . [I played with] Neighborhood kids because all my brothers and sisters, they were

Brothers in arms? Portuguese and Brazilian journalistic worlds compared

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Rui Alexandre Novais

2013-06-01

Full Text Available This study aims to gauge if there is a ‘de-territorialized’ Portuguese speaking journalistic community or whether diverse professional self-perceptions prevail amongst Portuguese and Brazilian counterparts. Based upon an extensive and manifold comparative analysis of 200 questionnaires – comprising the ‘journalism cultures’, their trust on social institutions’ and the ‘perceived influences on news work’ - it contrasts the cultural proximity of both countries, alongside a degree of globalization, with their rather dissimilar respective political and media contexts. It concludes that notwithstanding the expected psychological proximity and some signs of convergence between the two countries, the comparative evidence displays considerable differences which are the result of their respective institutional, social and cultural embedding. Thus, those partially different professional cultures prevent the existence of a translocal Portuguese speaking journalistic culture and corroborate the importance the contextual conditions

BROTHERS IN ARMS? PORTUGUESE AND BRAZILIAN JOURNALISTIC WORLDS COMPARED

Directory of Open Access Journals (Sweden)

Rui Alexandre Novais

2013-06-01

Full Text Available This study aims to gauge if there is a ‘de-territorialized’ Portuguese speaking journalistic community or whether diverse professional self-perceptions prevail amongst Portuguese and Brazilian counterparts. Based upon an extensive and manifold comparative analysis of 200 questionnaires – comprising the ‘journalism cultures’, their trust on social institutions’ and the ‘perceived influences on news work’ - it contrasts the cultural proximity of both countries, alongside a degree of globalization, with their rather dissimilar respective political and media contexts. It concludes that notwithstanding the expected psychological proximity and some signs of convergence between the two countries, the comparative evidence displays considerable differences which are the result of their respective institutional, social and cultural embedding. Thus, those partially different professional cultures prevent the existence of a translocal Portuguese speaking journalistic culture and corroborate the importance the contextual conditions

Hypospadias and increased risk for neurodevelopmental disorders.

Science.gov (United States)

Butwicka, Agnieszka; Lichtenstein, Paul; Landén, Mikael; Nordenvall, Anna S; Nordenström, Anna; Nordenskjöld, Agneta; Frisén, Louise

2015-02-01

Hypospadias (aberrant opening of the urethra on the underside of the penis) occurs in 1 per 300 newborn boys. It has been previously unknown whether this common malformation is associated with increased psychiatric morbidity later in life. Studies of individuals with hypospadias also provide an opportunity to examine whether difference in androgen signaling is related to neurodevelopmental disorders. To elucidate the mechanisms behind a possible association, we also studied psychiatric outcomes among brothers of the hypospadias patients. Registry study within a national cohort of all 9,262 males with hypospadias and their 4,936 healthy brothers born in Sweden between 1973 and 2009. Patients with hypospadias and their brothers were matched with controls by year of birth and county. The following outcomes were evaluated (1) any psychiatric (2) psychotic, (3) mood, (4) anxiety, (5) eating, and (6) personality disorders, (7) substance misuse, (8) attention-deficit hyperactivity disorder (ADHD), (9) autism spectrum disorders (ASD), (10) intellectual disability, and (11) other behavioral/emotional disorders with onset in childhood. Patients with hypospadias were more likely to be diagnosed with intellectual disability (OR 3.2; 95% CI 2.8-3.8), ASD (1.4; 1.2-1.7), ADHD (1.5; 1.3-1.9), and behavioral/emotional disorders (1.4; 1.2-1.6) compared with the controls. Brothers of patients with hypospadias had an increased risk of ASD (1.6; 1.3-2.1) and other behavioral/emotional disorders with onset in childhood (1.2; 0.9-1.5) in comparison to siblings of healthy individuals. A slightly higher, although not statistically significant, risk was found for intellectual disability (1.3; 1.0-1.9). No relation between other psychiatric diagnosis and hypospadias was found. This is the first study to identify an increased risk for neurodevelopmental disorders in patients with hypospadias, as well as an increased risk for ASD in their brothers, suggesting a common familial (genetic and

Electoral system and electoral campaign in Ancient Rome

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Notari Tamaš

2011-01-01

Full Text Available One of the most famous orators of the Antiquity, Marcus Tullius Cicero entered the election for the consul's position held in 64 B.C. arranged under extremely disturbed circumstances and he won the consulatus for 63 B.C. Difficulties were caused among others by the fact that an indebted nobleman called Lucius Sergius Catilina saw the only breakthrough for ensuring his political and financial survival in being elected consul, and manifested that in case he would lose he would be willing to take as well violent actions (later, he actually carried out his threats. The orator's younger brother, Quintus Tullius Cicero wanted to help his brother in his campaign foreseen as having quite a lot of turns; so, he wrote a manual for him on the lawful and illegal instruments that could be used in the elections. This work, Commentariolum petitionis (A Handbook for Applicants for Offices is the first summary of campaign strategy in the history of mankind. In addition to the evaluation of the given situation, the presentation (and exploitation of the weaknesses of counter nominees, the book provides advice on several counts that might possibly continue to have relevance even today. We do not know to what extent the experienced politician, Cicero adhered to his younger brother's advice; it is, however, a fact that he was elected consul, and as a consul he defeated Catilina's revolt in. 63 B.C.

Risk factors for testicular cancer: a case-control study in twins.

Science.gov (United States)

Swerdlow, A J; De Stavola, B L; Swanwick, M A; Mangtani, P; Maconochie, N E

1999-06-01

Early life and anthropometric risk factors for testicular cancer were examined in a case-control study in England and Wales in which affected male twins were compared with their unaffected male co-twins. Questionnaire data was obtained for 60 twin pairs. Significantly raised risk of testicular cancer occurred in twins who had longer arms and legs than their co-twin. There was a significant excess of testicular cancer reported in non-twin brothers, as well as in twin brothers, of cases. Risk was also significantly raised in relation to cryptorchidism. The results on limb length suggest that factors, perhaps nutritional, affecting growth before puberty, may be causes of testicular cancer. The results on risk in brothers add to evidence of a large genetic component in aetiology of the tumour. The risk associated with cryptorchidism in the twins accords with the hypothesis that cryptorchidism is causally associated with testicular cancer because it is a cause of the malignancy, rather than because the same maternal factors experienced in utero cause both conditions.

The LHC experiment control system: on the path to full automation

International Nuclear Information System (INIS)

Gaspar, C.; Alessio, F.; Cardoso, L.; Frank, M.; Garnier, J.C.; Herwijnen, E.V.; Jacobsson, R.; Jost, B.; Neufeld, N.; Schwemmer, R.; Callot, O.; Franek, B.

2012-01-01

LHCb is a large experiment at the LHC accelerator. The experiment control system is in charge of the configuration, control and monitoring of the different sub-detectors and of all areas of the online system. The building blocks of the control system are based on the PVSS SCADA System complemented by a control Framework developed in common for the 4 LHC experiments. This framework includes an 'expert system' like tool called SMI++ which is used for the system automation. The experiment's operations are now almost completely automated, driven by a top-level object called Big-Brother, which pilots all the experiment's standard procedures and the most common error-recovery procedures. The architecture, tools and mechanisms used for the implementation as well as some operational examples will be described. (authors)

Wien unter Ferdinand I. 1521–1564. Über die Verflechtungen von Fürst, Stadt und Residenz aus kunsthistorischer Perspektive / Vienna under Ferdinand I, 1521-1564. Relations between the prince, the town and the residence from the perspective of art history

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Renate Holzschuh-Hofer

2015-12-01

Full Text Available Driven by his political ambition to obtain the imperial title following his brother Charles V as well as being under the Ottoman threat, Ferdinand I had advocated Vienna’s establishment as the residential capital since 1522. The architecture of his main residence, the Vienna Hofburg, acquired with his imperial guiding principle a corresponding iconic character.

«Nerites»: contribución al estudio de la mitología marina de la antigua Grecia

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José Carlos Bermejo Barrera

1980-06-01

Full Text Available The present paper considers Aelian, NA XIV 28, which presents a secondary tradition found in two sailors’ tales about Nerites, the brother of the Nereids. Analysis shows that this typical character integrates the two codes of his myth, the zoological code and the mythical-personal code, in the context of Greek myths about the sea.

« L’influence de la franc-maçonnerie française dans le Département Oriental de Cuba dans les années 1820 – Les apports de la prosopographie »

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Agnès Renault

2009-01-01

Full Text Available After a first paper about the importance of the presence of the French Masons in Santiago de Cuba, between 1798 and 1808, this new work presents a second stage of the history of the Cuban Freemasonry in Santiago de Cuba. It begins in 1821, when the Frenchmen of Santiago de Cuba founded the lodge Humanité . This institution might have been created because of the comeback of the 1812 Spanish Constitution. This stage, during the trienio liberal , is very important. First, in this case, the founda tion of a lodge became legal, at the opposite of the first French lodges that were being displaced of the French colony towards another territory, meeting in secret. Some of the brothers were still French, but the new circ umstances and the best integration of the Frenchmen in Santiago de Cuba involved a major change with the introduction for the first time of Hispanic Cuban brothers. This phase is essential for the Cuban Freemasonry.

Searching the stars the story of Caroline Herschel

CERN Document Server

Ogilvie, Marilyn B

2011-01-01

Caroline Herschel is best known as the less significant sister of the astronomer William Herschel. Yet the romantic notion of her tirelessly working for her brother while he made his studies of the heavens, documenting his discoveries so he could achieve greatness in the scientific world, couldn't be further from the truth. When Caroline wasn't working as her brother's assistant, she was sweeping the stars with her own small telescope given to her by William. Not only did she unearth three important nebulae, but she discovered no fewer than eight comets in her own right. When William beca

24. Losing Oneself: Autobiography, Memory, Vision

OpenAIRE

Holland, John

2013-01-01

Henry James begins A Small Boy and Others by explaining why he found it difficult to respond to a request. Having been asked, shortly after William’s death, to write a memoir of his brother, he is forced to explain that he cannot do so in a direct and simple way, for he is not the master of his own thoughts. The very attempt to recall his experiences with his older brother has immersed him in a flood of associations. Since ”it was to memory in the first place that my main appeal for particula...

A TSHβ Variant with Impaired Immunoreactivity but Intact Biological Activity and Its Clinical Implications

DEFF Research Database (Denmark)

Pappa, Theodora; Johannesen, Jesper; Scherberg, Neal

2015-01-01

BACKGROUND: Thyrotropin (TSH) deficiency caused by TSHβ gene mutations is a rare form of congenital central hypothyroidism. Nine different TSHβ gene mutations have been reported, all with clinical manifestations. The aim was to identify the genetic cause of undetectable TSH levels in two siblings......). This variant was found in 12 out of 5008 alleles in the 1000 Genomes project (all South Asian). Serum TSH of the two brothers was undetectable in two of five platforms, both produced by Siemens, whereas TSH levels of the heterozygous brother and mother were half compared to the other three platforms (Roche...

How important is cultural background for the level of intergenerational mobility?

DEFF Research Database (Denmark)

Schnitzlein, Daniel D.

Using results on brother correlations in permanent earnings for different groups of second generation immigrants based on administrative data from Denmark, this letter analyzes the role of cultural background in the determination of the level of intergenerational mobility. The results indicate th...... that cultural background is not a major determinant of the level of intergenerational economic mobility.......Using results on brother correlations in permanent earnings for different groups of second generation immigrants based on administrative data from Denmark, this letter analyzes the role of cultural background in the determination of the level of intergenerational mobility. The results indicate...

Une épouse à Londres

OpenAIRE

Hardy, Thomas

2013-01-01

Published in Poems of the Past and the Present (Harper & Brothers, 1901), the poem appears in the “War Poems” section of the collection, and bears the date ”December 1899”. The context is that of the Second Boer War (1899-1902). Paru dans Poems of the Past and the Present (Harper & Brothers, 1901), le poème figure dans la section des poèmes de guerre (“War Poems”) du recueil. Daté de décembre 1899, il se place donc dans le contexte de la Seconde Guerre des Boers (1899-1902).

Siblings and children's time use in the United States

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Rachel Dunifon

2017-11-01

Full Text Available Background: Eighty-two percent of children under age 18 live with at least one sibling, and the sibling relationship is typically the longest-lasting family relationship in an individual's life. Nevertheless, siblings remain understudied in the family demography literature. Objective: We ask how having a sibling structures children's time spent with others and in specific activities, and how children's time and activities with siblings vary by social class, gender, and age. Methods: We use time diary data from the US Panel Study of Income Dynamics' Child Development Supplement (PSID-CDS, comparing the time use of children with and without siblings and presenting regression-adjusted descriptive statistics on patterns among those with siblings. Results: Children with siblings spend about half of their discretionary time engaged with siblings. They spend less time alone with parents and more time in unstructured play than those without siblings. Brothers and more closely spaced siblings spend more time together and more time in unstructured play. For example, boys with at least one brother spend five more hours per week with their siblings and over three more hours per week in unstructured play than boys with no brothers. Conclusions: The presence and characteristics of siblings shape children's time use in ways that may have implications for child development. Contribution: This is the first study to use children's time diary data to examine how the presence and characteristics of siblings structure ways in which children spend their time. This contributes to our broader understanding of sibling relationships and family dynamics.

Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.

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Doug P Vanderlaan

Full Text Available In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect. In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768. Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.

The important semiotic indicators of Dostoyevsky's emotional image

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Iskhakova Z.Z.

2016-12-01

Full Text Available This article is devoted to finding the emotional semiotic character of F. Dostoevsky that is expressed by the key characters' behaviour in 'The Gambler', 'Idiot', The Brothers Karamazov'. The object of the study is emotionally painted speeches of characters in his works. The subject of the study is emotive signs indices in emotional texts of Fyodor Dostoevsky.

Disseminated Soft Tissue Infection and Sepsis with Stenotrophomonas maltophilia in a Bone Marrow Transplant Patient

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Jeffrey H Lipton

1996-01-01

Full Text Available A 32-year-old female presented with aplastic anemia and subsequently underwent a one-antigen mismatched bone marrow transplant from her brother. She failed to engraft and a second graft was attempted. Protracted neutropenia of three months’ duration despite the use of broad spectrum antibiotics occurred. Stenotrophomonas (Xanthomonas maltophilia metastatic cellulitis developed that did not respond to appropriate antibiotics.

Sleep-EEG in dizygotic twins discordant for Williams syndrome.

Science.gov (United States)

Bódizs, Róbert; Gombos, Ferenc; Szocs, Katalin; Réthelyi, János M; Gerván, Patrícia; Kovács, Ilona

2014-01-30

Reports on twin pairs concordant and discordant for Williams syndrome were published before, but no study unravelled sleep physiology in these cases yet. We aim to fill this gap by analyzing sleep records of a twin pair discordant for Williams syndrome extending our focus on presleep wakefulness and sleep spindling. We performed multiplex ligation-dependent probe amplification of the 7q11.23 region of a 17 years old dizygotic opposite-sex twin pair discordant for Williams syndrome. Polysomnography of laboratory sleep at this age was analyzed and followed-up after 1.5 years by ambulatory polysomnography. Sleep stages scoring, EEG power spectra and sleep spindle analyses were carried out. The twin brother showed reduced levels of amplification for all of the probes in the 7q11.23 region indicating a typical deletion spanning at least 1.038 Mb between FKBP6 and CLIP2. The results of the twin sister showed normal copy numbers in the investigated region. Lower sleep times and efficiencies, as well as higher slow wave sleep percents of the twin brother were evident during both recordings. Roughly equal NREM, Stage 2 and REM sleep percents were found. EEG analyses revealed state and derivation-independent decreases in alpha power, lack of an alpha spectral peak in presleep wakefulness, as well as higher NREM sleep sigma peak frequency in the twin brother. Faster sleep spindles with lower amplitude and shorter duration characterized the records of the twin brother. Spectra show a striking reliability and correspondence between the two situations (laboratory vs. home records). Alterations in sleep and specific neural oscillations including the alpha/sigma waves are inherent aspects of Williams syndrome.

Gendered effects of siblings on child malnutrition in South Asia: cross-sectional analysis of demographic and health surveys from Bangladesh, India, and Nepal.

Science.gov (United States)

Raj, Anita; McDougal, Lotus P; Silverman, Jay G

2015-01-01

This study examines the effects of number and sex of siblings on malnutrition of boys and girls under-5 in South Asia. Cross-sectional analyses were conducted on Demographic and Health Surveys data on children under-5 in Bangladesh (N = 7,861), India (N = 46,655) and Nepal (N = 2,475). Data were pooled across countries, and multinomial logistic regression was used to assess the relationship between number and sex of siblings and malnutrition outcomes (wasting, stunting, underweight; based on anthropometric data), adjusting for country and key social and maternal-child health indicators in sex stratified analyses. Number of brothers increased the odds for severe wasting [1 vs. 0 brothers adjusted odds ratio (AOR) = 1.31, 95 % CI = 1.11, 1.55; 2 vs. 0 brothers AOR = 1.36, 95 % CI = 1.07, 1.73] for girls but not boys. Having more male siblings and more female siblings increased the odds of stunting for boys and girls, but effect of 3+ sisters on severe stunting was significantly stronger for girls than boys (girls- 3+ vs. 0 sisters AOR = 2.25, 95 % CI = 1.88, 2.70; boys- 3+ vs. 0 sisters AOR = 1.37, 95 % CI = 1.13, 1.67). For underweight, three or more sisters increased the odds for severe underweight for girls (AOR = 1.27, 95 % CI = 1.04, 1.57) but not boys. Having brothers heightens girl risk for acute malnutrition (wasting), where having multiple sisters increases girl risk for chronic malnutrition (stunting/underweight). Boy malnutrition is less affected by siblings. Findings suggest that issues of son preference/daughter aversion may affect child malnutrition in South Asia.

[Jealousy between siblings in early childhood. Nursing assessment based on a case study].

Science.gov (United States)

Puig-Plana, María Pilar

2010-01-01

Childhood jealousy, when a little brother or sister is born, has always been a subject treated within the family environment. Parent's attitude in their interaction with their offspring may increase the response of the jealous child. The emotional expressions of the jealous child may lead to behaviour changes, that may occasionally put the physical integrity of the newborn at risk, since it is the most vulnerable in the family group. In view of the above mentioned, a case of a three-year-old child living with his parents and his nine-month-old sister, is presented. The child shows characteristic behaviour changes of jealousy, such as, rebelliousness, aggressiveness and hyperactivity. The brother's psychomotor discomfort leads to a proneness to accidents for the baby girl and the obvious parental concern. For these reasons nursing intervention in the family group was proposed, based on the theoretical Virginia Henderson Needs Model. The actions will come from the older brother and parents. The aim of the nursing intervention is to lead the behaviour changes in order to re-establish a safe and healthy family environment. Copyright 2009 Elsevier España, S.L. All rights reserved.

Does incest cause homosexuality?

Science.gov (United States)

Cameron, P; Cameron, K

1995-04-01

A random sample of 5,182 adults from 6 U.S. metropolitan areas were questioned about incestuous sexual relationships during childhood. Incest was disproportionately reported by both male and female bisexuals and homosexuals. 148 gays (7.7% of the sample) reported 14 (50%) of same-sex, and 7 (22%) of opposite-sex incestuous experiences, and 20 (69%) of same-sex and 2 (3%) of opposite-sex sexual experiences with other relatives. 88 lesbians (3% of the sample) reported 2 (33%) of same-sex incest and 7 (9%) of opposite-sex incest and 1 (17%) of same-sex and 10 (13%) of opposite-sex sexual experiences with other relatives. 12% of 98 male homosexuals vs 0.8% of 1,224 male heterosexuals with a brother reported brother-brother incest. These findings are consonant with those of other studies in which disproportionately more incest by homosexuals was reported. As opposed to an evolutionary genetic hypothesis, these data support the alternative that homosexuality may be learned, since homosexuals do not produce children at sustainable levels and the incidence of homosexuality varies as a function of various social factors. Incest cannot be excluded as a significant basis for homosexuality.

Ausambad Newfoundlandi eestisoost seenesõpradele / foto: Helen Spencer

Index Scriptorium Estoniae

2008-01-01

Newfoundlandis asuva Brother Brennan Environmental Education Centre (BBEEC) poolt korraldadavatest seenekursustest, mille õppejõuks kutsuti Newfoundlandis seenehuvilistena tuntud Maria ja Andrus Voitk

Relationship of order and number of siblings to perceived parental attitudes in childhood.

Science.gov (United States)

Kitamura, T; Sugawara, M; Shima, S; Toda, M A

1998-06-01

Despite the increasingly recognized link between perceived parenting behavior and the onset of psychopathology in adults, studies of the possible determinants of perceptions of parenting behavior are rare. In a sample of 1,145 pregnant Japanese women, correlations were examined between the numbers and sexes of siblings and perceived rearing practices, as rated by the Parental Bonding Instrument (PBI; Parker, Tupling, & Brown, 1979). The participants with more elder sisters viewed their parents' attitudes as less caring, whereas those with more brothers, particularly younger brothers, viewed their parents' attitudes as less overprotective. However, the proportion of the variance of all the PBI scores explained by different types of siblings was very small.

The Night Sky, The Forgotten Nature: Uncovering the Impact of One Television Programme on Astronomy Communication in Iran

Science.gov (United States)

Nazemi, P.

2017-09-01

In 2001, two brothers known as the Saffarianpour brothers started a television programme on Iranian state television called Aseman-e-shab (The Night Sky). The programme, which explores astronomy and space science, became one of the longest-running television shows in the history of Iranian television and played a major role in the public communication of science and astronomy. It inspired many of the next generation of Iranian scientists and astronomers and played a key role in the advancement of science journalism and science communication in Iranian media. This article outlines a brief history of the show and its producer and describes the role they played in Iranian society.

77 FR 75503 - Wright Brothers Day, 2012

Science.gov (United States)

2012-12-20

... Wright pursued their lifelong dream. Like so many Americans before and after them, these two men achieved... stay ahead of the curve and keep America moving forward. With their game-changing feat, the Wright...

Unequal brothers : are homeopathy and hormesis linked?

Science.gov (United States)

Oberbaum, Menachem; Frass, Michael; Gropp, Cornelius

2015-04-01

The debate between those who believe homeopathy and hormesis derive from the same root and those who believe the two are different phenomena is as old as hormesis. It is an emotionally loaded discussion, with both sides fielding arguments which are far from scientific. Careful analysis of the basic paradigms of the two systems questions the claim of the homeopaths, who find similarities between them. The authors discuss these paradigms, indicating the differences between the claims of homeopathy and hormesis. It is time for thorough and serious research to lay this question to rest. One possible approach is to compare the activity of a hormetic agent, prepared in the usual way, with that of the same agent in the same concentration prepared homeopathically by serial dilution and succussion. Copyright © 2015. Published by Elsevier Ltd.

Kino plaadimasinas / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

Areeni muusikakriitikud kuulavad filmimuusika heliplaate: "O Brother, Where Art Thou?", "The Royal Tenenbaums", "Amelie From Montmartre", "Moulin Rouge", "Training Day", "Mulholland Drive", "Ocean's 11"

Pop / Tõnis Kahu

Index Scriptorium Estoniae

Kahu, Tõnis, 1962-

2008-01-01

Heliplaatidest: Chemical Brothers "Brotherhood", Plutonium 74 "Peittoalueen ulkopuolella", Disturbed "Indestructible", Thomas Feiner & Anywhen "The Opiates Revised", DefRage "Save Us from Religion", Kago "Mopskassi maja"

AHP 47: YELLOW-HEAD HORSE

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Sangs rgyas bkra shis སངས་རྒྱས་བཀྲ་ཤིས།

2017-04-01

Full Text Available My family had a stallion we called Rta mgo ser 'Yellow-Head Horse'. Father and two of his brothers occasionally rode it. Father said that Yellow-Head was very wild when it was taken to join local horseraces. I didn't believe that because Yellow-Head was very gentle when Mother rode it to the local monastery and also when I rode it.

“A PERSISTENT EXCEPTION TO TEXTBOOK ECONOMICS”: A HISTORICAL OVERVIEW OF INTERNATIONAL AIRLINES

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Erik Benson

2005-01-01

Full Text Available The recent centennial of the Wright Brothers' flight stimulated study of the history of aviation in general and this historical overview of international airlines in particular. International airlines are commercial enterprises, but their history suggests that the economics behind their development was often overridden lypolitical, diplomatic, strategic, imperial, cultural, and emotional pressures. International airlines have not always been economically rational enterprises.

Sir John Struthers (1823-1899), Professor of Anatomy in the University of Aberdeen (1863-1889), President of the Royal College of Surgeons of Edinburgh (1895-1897).

Science.gov (United States)

Kaufman, M H

2015-11-01

Between 1841 and 1845 John Struthers attended both the University of Edinburgh and some of the various Extra-mural Schools of Medicine associated with Surgeons' Hall. While a medical student he became a Member of the Hunterian Medical Society of Edinburgh and later was elected one of their Annual Presidents. He graduated with the MD Edin and obtained both the LRCS Edin and the FRCS Edin diplomas in 1845. Shortly afterwards he was invited to teach Anatomy in Dr Handyside's Extra-mural School in Edinburgh. The College of Surgeons certified him to teach Anatomy in October 1847. He had two brothers, and all three read Medicine in Edinburgh. His younger brother, Alexander, died of cholera in the Crimea in 1855 while his older brother James, who had been a bachelor all his life, practised as a Consultant Physician in Leith Hospital, Edinburgh, until his death.When associated with Dr Handyside's Extra-mural School in Edinburgh, John taught Anatomy there until he was elected to the Chair of Anatomy in Aberdeen in 1863. Much of his time was spent in Aberdeen teaching Anatomy and in upgrading the administrative facilities there. He resigned from this Chair in 1889 and subsequently was elected President of Leith Hospital from 1891 to 1897. This was in succession to his older brother, James, who had died in 1891. Later, he was elected President of the Royal College of Surgeons of Edinburgh from 1895 to 1897 and acted as its Vice-President from 1897 until his death in 1899. In 1898, Queen Victoria knighted him. His youngest son, John William Struthers, was the only one of his clinically qualified sons to survive him and subsequently was elected President of the Edinburgh College of Surgeons from 1941 to 1943. © The Author(s) 2014.

تصاویر الثوار والخارجین عن حکم الأباطرة المغول فی الهند (932-1273هـ/1526-1857م

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DR. Amal Abdul Salam Al Sayed

2017-01-01

Full Text Available The aim of this research is to study the portrayal of the revolutionaries and the outlaws of the Mongol emperors in India, highlighting the most important revolutions and stages of each revolution and how to eliminate them and their main leaders, whether these revolutions inside the Mongol house of the emperor's brothers or cousins or revolutions The leaders of the Mughal army, such as the Uzbek officers' revolutions led by the brothers Ali Qali Khan and Bahadir Khan al-Shaibani, or revolutions that are a popular uprising of the Indian people, the Mongol emperors, Such as the revolution of merahta in the era of the Emperor Orangzip, and research is concerned with the study of the regions in which these revolutions and their geographical nature, such as the province of Bengal and Gujarat, as well as the most important strongholds and fortresses of the rebels such as Fort Sourt and the Castle of Uzbeks, Was carried out by some members of the Mongol house, such as Adham Khan, Akbar's brother Akbar's breast, or Perm Khan, Emperor Akbar's minister, Khan Jahan, the minister of Emperor Shahghan, and other prominent figures in the Mongol court, And of course, through a number of images that illustrated the stages of these revolutions and the way followed by the emperors of the Mongols in the elimination of such revolutions and rebel movements, and through the researcher was able to reach a number of important results through which to know the history of India's political and social history is documented by the affirmation of events and historical and military events

Chronic central serous choroidopathy with severe visual loss in hyperopic microphthalmic identical twins

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Fabry, Annelies

2011-01-01

Full Text Available Objective: To report chronic central serous choroidopathy with severe visual loss in hyperopic microphthalmic identical twins. Methods: The index patient was first examined in 1994, at age 31, and has been followed up closely for 17 years. He had repeated fluorescein and indocyanine green angiograms, OCT, ultrasound biometry, and recently also autofluorescence and EDI OCT. His twin brother was first examined in 2010, at age 47, and had a similar extensive exploration. Results: The index patient had a mean refractive error of +6 D OU and VA was 20/32++ in the RE and 20/200 in the LE in 1994. Vision slowly went down to 20/800+ in the RE and 20/600 in the LE in 2011. His twin brother has a mean refractive error of +6 D OU and VA 20/400 OU. Both have a short axial length of the eye, a thick choroid with dilated vessels, and central serous choroidopathy with cystic degeneration of the macula and retina in the posterior pole. Conclusions: We add to the reported complications of microphthalmos, chronic central serous choroidopathy.

Discourses of the I: The Panic of Identity in Edward Albee’s Me, Myself and I

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Prohászka-Rád Boróka

2016-12-01

Full Text Available “Hello, there! My name is OTTO. [...] I want to make trouble because I want to make things even more complicated than they are around here, and then maybe I can get out of this whole mess – this family and everything. Let’s see: my name is OTTO. I have an identical twin brother. I’m trying to get rid of him, rid of all of them – but it’s not easy: you know how twins are; well, maybe you don’t” – OTTO, one of the identical twin brothers (both named Otto of Edward Albee’s Me, Myself and I opens the play addressing the audience. Albee’s wit and sharp irony dominate the play, managing to “engage, to upset, to trouble” audiences and readers. In my paper I analyze the methods Albee employs in transforming the stage into a meta- and intertextual “space” subverting and undermining any belief in identity and language as fixed, stable and functional “entities.”

Kindergarten students’ levels of understanding some science concepts and scientific inquiry processes according to demographic variables (the sampling of Kilis Province in Turkey

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Nail İlhan

2016-12-01

Full Text Available The purpose of this study is to identify the kindergarten students’ levels of understanding some science concepts (LUSSC and scientific inquiry processes (SIP and compare their LUSSC and SIP in terms of some demographic variables. Also, another purpose of this study is to identify the predictive power of those demographic variables over the kindergarten students’ LUSSC and SIP. This study was conducted according to quantitative research design. The study group consisted of 335 kindergarten students from 20 different rural and urban schools. In the study, the scale for “Turkish Kindergarten Students’ Understandings of Scientific Concepts and Scientific Inquiry Processes” was used. According to some variables (such as mother’s education level and family structure, there was a statistically significant difference between students’ mean scores for LUSSC and between students’ mean scores for SIP. Within the scope of this study, it was found that among the predictor variables (age, family’s income level, and number of brother/sister were significant predictors for LUSSC, and number of brother/sister was a significant predictor for SIP.

Whole Exome Sequencing Reveals Compound Heterozygosity for Ethnically Distinct PEX7 Mutations Responsible for Rhizomelic Chondrodysplasia Punctata, Type 1

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Jessie C. Jacobsen

2015-01-01

Full Text Available We describe two brothers who presented at birth with bone growth abnormalities, followed by development of increasingly severe intellectual and physical disability, growth restriction, epilepsy, and cerebellar and brain stem atrophy, but normal ocular phenotypes. Case 1 died at 19 years of age due to chronic respiratory illnesses without a unifying diagnosis. The brother remains alive but severely disabled at 19 years of age. Whole exome sequencing identified compound heterozygous stop mutations in the peroxisome biogenesis factor 7 gene in both individuals. Mutations in this gene cause rhizomelic chondrodysplasia punctata, type 1 (RCDP1. One mutation, p.Arg232∗, has only been documented once before in a Japanese family, which is of interest given these two boys are of European descent. The other mutation, p.Leu292∗, is found in approximately 50% of RCDP1 patients. These are the first cases of RCDP1 that describe the coinheritance of the p.Arg232∗ and p.Leu292∗ mutations and demonstrate the utility of WES in cases with unclear diagnoses.

Genetic or Psychogenic? A Case Study of “Folie à Quatre” Including Twins

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Tohru Ohnuma

2015-01-01

Full Text Available Shared psychotic disorder, characterized by shared delusion among two or more subjects (termed “Folie à deux,” “trois,” etc., is often associated with strong religious beliefs or social isolation, factors creating strong psychological sympathy. Recently, we treated a rare familial case of “Folie à quatre” in central Tokyo without such influences. The proband was a schizophrenia patient and younger brother within monozygotic twins. Positive symptoms were “transmitted” to remaining family members, his elder brother, mother, and father father, in a relatively short period of three months. Although the pathophysiology of these positive symptoms (delusions and hallucinations remains unclear, the transmission pattern suggests the primacy of social and environmental factors (and/or their interaction, while genetics appeared less influential in this “Folie à famille.” Although undiagnosed psychoses in the whole family cannot be excluded, they did not share the other negative schizophrenia symptoms of the proband. A strong familial connection appeared to be the most important factor for the common delusion and hallucination.

Regional Food Distribution Characteristics and a Methodology for Redistribution in Accordance with Crisis Relocation. Appendices.

Science.gov (United States)

1980-07-01

PREDLETON 1 1 1,500 * TOTAL 4 1 3 5,250 WILLIAMS BROTHERS CO TALLAPOOSA GA GA HARALSON 1 1 750 ** TOTAL 1 1 750 WILLIAMS BROTHERS GROCERY CO TIFTON GA GA ...T I 0 N ACER COUNTY STRS 1MIL MIL MIL MIL MIL ACV (000) A AND P TEA CO ATLANTA GA GA COBS 1 1 7,000 (Family Centers) GA DOUGHERTY 1 1 12,000 SC...RICILAND 1 1 ioooo TOTAL 3 1 2 29,000 A AND P TEA CO ATLANTA GA AL BAREOUR 1 1 1,500 AL BULLOCK 1 1 1,500 AL BUTLEP 1 1 3,000 AL CHAM3ERS 1 1 1,500 AL

75 FR 68911 - Regulations Under the Genetic Information Nondiscrimination Act of 2008

Science.gov (United States)

2010-11-09

..., biological mother, the mother's brothers, sisters, and their children, maternal grandfather, maternal... risk of conditions such as cystic fibrosis, sickle cell anemia, spinal muscular atrophy, and fragile X...

Uued plaadid

Index Scriptorium Estoniae

1999-01-01

Uutest heliplaatidest Ivo Linna & Rock Hotel "Kõva ketas", Hendrik Sal-Saller "1994-1996", Chemical Brothers "Surrender", Mike & The Mechanics "M6", Bomfunk Mc"s "In Stereo", Jamiroquai "Synkronized"

Plaadid / Heili Vaus-Tamm

Index Scriptorium Estoniae

Vaus-Tamm, Heili, 1961-

2003-01-01

Uutest plaatidest Andras Schiff "Goldberg Variations", Yes "Remixes", "Chill: Brasil 2", "The Fighting Temptations soundtrack", Wheatus "Hand Over Your Loved Ones", Peaches "Fatherfucker", Chemical Brothers "Singles 93-03"

20 CFR 410.633 - Additional parties to the hearing.

Science.gov (United States)

2010-04-01

... OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Determinations of Disability, Other Determinations... hearing. A widow, child, parent, brother, sister, or representative of a decedent's estate, who makes a...

Two Silent Brothers. Althusser and Foucault at the Crossroads of Ideology

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Diego Melegari

2014-07-01

Full Text Available The article aims to reinterpret the relationship between Louis Althusser and Michel Foucault on the specific ground of the notion of "Ideology." If Foucault's critique addresses initially the alleged opposition between ideological discourse and scientific discourse, this does not seem to fade in the seventies, despite the convergence of Foucault's "microphysics of power"with Althusser's insistence on the "material" character of ideology. To explain the persistence of this comparison and of this tension the author shows how with it are involved highly problematic knots for the whole Foucault's thought: the status of representation and truth, the inner existence and temporality of capitalism and, in particular, the relationship between criticism and politics.

Rapitav sõna : Igakuine hip-hopi infopunkt / Kozy

Index Scriptorium Estoniae

Kozy, pseud.

1999-01-01

Uutest heliplaatidest Snoop Dogg "No Limit Top Dogg", Public Enemy "There's A Poison Goin" On"", RZA "Hits", Missy Misdemeanor Elliott "Da Real World", Insane Clown Posse "The Amazing Jeckel Brothers"

Does Women’s Preference for Highbrow Culture Begin in the Family?

DEFF Research Database (Denmark)

Jæger, Mads Meier; Katz-Gerro, Tally

2015-01-01

participation among brothers and sisters from the same family and report three findings: (1) gender differences in highbrow leisure participation are largely unrelated to family background, (2) there is little evidence that parents engage in gender-specific cultural socialization, and (3) socioeconomic position......Research shows that women are more likely than men to participate in highbrow leisure activities, but we do not know whether this gap develops within the family at an early age or is the outcome of socioeconomic differences between men and women later in life. We compare highbrow leisure...... and family obligations account for less than 20% of brother-sister differences in highbrow leisure participation. Our results suggest that gender differences in highbrow leisure participation originate in factors outside the family....

This is My Family

OpenAIRE

Yeğen, Hale Nur; Çetin, Merve

2017-01-01

Me and my family, Families poem, Mother-Father, Brother-Sister, Grandparents, Uncle-Aunt, Cousin, Family, Family handgame, My family tree, Activities (Three In a Family), Digital Games, A family poem, Quiz

Kuula. Kuu artist Carla Bruni. Kuu plaat / Mart Juur

Index Scriptorium Estoniae

Juur, Mart, 1964-

2008-01-01

Lauljast Carla Brunist. Heliplaatidest: "Mamma mia", The Feeling "Join With Us", The Chemical Brothers "Brotherhood", Pia Fraus "Ten Remixes of Yenissey", Katy Perry "One of the Boys", Lady Gaga "The Fame"

Detection of combined genomic variants in a Jordanian family with ...

Indian Academy of Sciences (India)

2Department of Surgery, Faculty of Medicine, University of Jordan, Amman 11942, Jordan ... brothers with sub-clinical hyperthyroidism, and their father were heterozygous ... Journal of Genetics, Vol. ..... However, further investigations should.

Popmuusika / Valner Valme

Index Scriptorium Estoniae

Valme, Valner, 1970-

2006-01-01

Uutest heliplaatidest Yeah Yeah Yeahs "Show Your Bones", Cesaria Evora "Rogamar", Aqua Bassino "Rue De Paris", A-Rühm "Leegion", Prefuse 73 "Security Screenings", Bauchklang "Vocal Groove Project", Scala & Kolancy Brothers "Grezenlos"

42 CFR 51c.304 - Governing board.

Science.gov (United States)

2010-10-01

... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an... procedures, salary and benefit scales, employee grievance procedures, and equal opportunity practices; (iii...

38 CFR 21.374 - Authorization for travel of attendants.

Science.gov (United States)

2010-07-01

... severity of the veteran's disability. Attendants may only be used to enable a veteran to attend... or marriage is the veteran's (i) Spouse, (ii) Parent, (iii) Child, (iv) Brother, (v) Sister, (vi...

The Sacramental and Moral-Educational Function of the Christian Orthodox Cult

Directory of Open Access Journals (Sweden)

Miron Vasile

2014-11-01

Full Text Available The Christian Orthodox Cult intervenes for our Salvation and blessing, gives us the possibility to cherish God and to offer Him our gratitude for the bounties we receive through religious services. This divine Cult helps us stay in touch with Him, deepen our faith, clean our sense, enlighten our mind, become stronger in our decision of doing good deeds and live like brothers in the spirit of the Christian love.

The betrayal of Edom: Remarks on a claimed tradition

Directory of Open Access Journals (Sweden)

Bob Becking

2016-09-01

Full Text Available Biblical and post-Biblical texts refer to the tradition of the betrayal of Edom. During theconquest the brother-nation of Edom would have betrayed Judah by choosing sides with the Babylonians. Historical and archaeological evidence for this ‘fact’ is absent or not convincing. It is argued that the occupation of Southern Judah by the Edomites in late Babylonian and/or Persian times would have been the source of this claimed tradition.

Driver’s Big Brother: How Smartphones Can Increase Driver’s Awareness

Directory of Open Access Journals (Sweden)

Ashraf Khalil

2012-10-01

Full Text Available Using mobile devices while driving has been widely shown to pose serious safety risk. Various approaches aim at mitigating the risk of mobile devices while driving. Some initiatives have focused on increasing drivers’ awareness of such potential risk. Along the same vein, we present a model, and its implementation, for assessing the degree of distraction that drivers experience while using phones during driving. Based on data collected during each driving session, the application gives statistics, such as keypad interaction, number and length of phone calls and the driving speed, to the driver. This should increase the awareness of drivers by helping them understand how much distraction they got involved with during driving and how much hazardous they can be to themselves and to others. Our experiments with drivers demonstrated the potential of the application at highlighting risky behavior, promoting awareness and motivating better driving.

Cluster fusion-fission dynamics in the Singapore stock exchange

Science.gov (United States)

Teh, Boon Kin; Cheong, Siew Ann

2015-10-01

In this paper, we investigate how the cross-correlations between stocks in the Singapore stock exchange (SGX) evolve over 2008 and 2009 within overlapping one-month time windows. In particular, we examine how these cross-correlations change before, during, and after the Sep-Oct 2008 Lehman Brothers Crisis. To do this, we extend the complete-linkage hierarchical clustering algorithm, to obtain robust clusters of stocks with stronger intracluster correlations, and weaker intercluster correlations. After we identify the robust clusters in all time windows, we visualize how these change in the form of a fusion-fission diagram. Such a diagram depicts graphically how the cluster sizes evolve, the exchange of stocks between clusters, as well as how strongly the clusters mix. From the fusion-fission diagram, we see a giant cluster growing and disintegrating in the SGX, up till the Lehman Brothers Crisis in September 2008 and the market crashes of October 2008. After the Lehman Brothers Crisis, clusters in the SGX remain small for few months before giant clusters emerge once again. In the aftermath of the crisis, we also find strong mixing of component stocks between clusters. As a result, the correlation between initially strongly-correlated pairs of stocks decay exponentially with average life time of about a month. These observations impact strongly how portfolios and trading strategies should be formulated.

CNGA3 mutations in two United Arab Emirates families with achromatopsia.

Science.gov (United States)

Ahuja, Yachna; Kohl, Susanne; Traboulsi, Elias I

2008-07-10

ACHROMATOPSIA RESULTS FROM MUTATIONS IN ONE OF THREE GENES: cyclic nucleotide-gated channel, alpha-3 (CNGA3); cyclic nucleotide-gated channel, beta-3 (CNGB3); and guanine nucleotide-binding protein, alpha-transducing activity polypeptide 2 (GNAT2). We report the responsible mutations in two United Arab Emirates families who have this autosomal recessive disease. Clinical examinations were performed in seven patients from three nuclear families. Molecular genetic testing for common CNGA3 and CNGB3 mutations was undertaken using standard protocols. All patients were extremely light sensitive and had reduced visual acuity and no color perception. Fundus examinations did not show any visible abnormalities. After further pedigree analysis, two of the families were found to be linked through the paternal line. Two mutations in CNGA3 were identified: Arg283Trp and Gly397Val. Family A, the larger pedigree, had one branch in which two sisters and one brother were homozygous for the Gly397Val mutation and another branch in which a brother and sister were compound heterozygous for both aforenamed mutations. Family B, however, only had two brothers who were homozygous for the Arg283Trp mutation. Achromatopsia in these two United Arab Emirates families results from two different mutations in CNGA3. Two branches of the same pedigree had individuals with both homozygous and compound heterozygous disease, demonstrating a complex molecular pathology in this large family.

Adjustment of children who have a sibling with Down syndrome: perspectives of mothers, fathers and children.

Science.gov (United States)

Cuskelly, M; Gunn, P

2006-12-01

A number of methodological weaknesses have contributed to our relatively poor understanding of the impact on children of having a brother or sister with a disability. These include a focus on poor adjustment, using multidiagnostic groups, inadequate matching, and a failure to consider the perspectives of children and parents together. This study compared the adjustment of 53 siblings of a child with Down syndrome with a comparison group of siblings of children who were developing typically. Children were matched on a case-by-case basis for gender, age and position in family. Families were matched for family size and father's occupation. The age range of the target siblings was 7-14 years. Data were gathered from mothers, fathers and siblings. There were no significant differences between the groups on adjustment measures. These included parent perceptions of externalizing and internalizing behaviours, parent perceptions of sibling competence, and sibling perceptions of their own competence and self-worth. Associations between measures of adjustment and child reports of their contribution to household functioning depended on sex rather than group membership. There was an association between parental reports of externalizing behaviour and sibling relationships with the brother/sister closest in age. Having a brother or sister with Down syndrome does not inevitably lead to poor adjustment. Examination of within-family processes would appear to be more useful in identifying children at risk than merely group membership.

32 CFR 751.5 - Definitions.

Science.gov (United States)

2010-07-01

..., snags, or stains on clothing. Claims that electrical or electronic devices were damaged by a power surge...) Spouse; (ii) Child or children; (iii) Father, mother, or both; (iv) Brother, sister, or both. (b...

17 CFR 210.9-03 - Balance sheets.

Science.gov (United States)

2010-04-01

... the beginning of the period, new loans, repayments, and other changes. (Other changes, if significant...; siblings; mothers and fathers-in-law; sons and daughters-in-law; and brothers and sisters-in-law. Ordinary...

Neuronal ceroid-lipofuscinosis, a type of amaurotic family idiocy: clinical and pathological study of four cases

Directory of Open Access Journals (Sweden)

Luciano de Souza Queiroz

1974-03-01

Full Text Available Neuronal ceroid-lipofuscinosis (NCL is a recent term, proposed for acurate designation of the late-onset types of Amaurotic Family Idiocy (AFI. Histopathology shows ubiquitous intraneuronal accumulation of lipopigments, being the most important factor for characterization of the entity at present time. Biochemical changes and pathogenesis are obscure. NCL is in contrast to the infantile type of AFI (Tay-Sachs disease, in which intraneuronal accumulation of gangliosides (sphingolipids is due to the well known deficiency of a lysosomal enzyme. The authors report on four cases of NCL, two brothers of the late infantile (Jansky-Bielschowsky type and a brother and a sister of the juvenile (Spielmeyer-Sjögren type. One autopsy and three cortical biopsies revealed moderate to severe distention of the neurons by lipopigment, with nerve cell loss, gliosis and cerebral atrophy. Lipopigment was also increased in liver, heart and spleen. The patients were the first in Brazilian literature in whom the storage material was identified as lipopigment by histochemical methods. A brief summary of the clinical features of NCL is presented, and relevant problems are discussed, concerning interpretation of the nature of the storage material, and significance of the disease for gerontological research.

LA CRISIS FINANCIERA: ¿ESTAFA, MALA GESTIÓN EMPRESARIAL, MAL MANEJO MACROECONÓMICO O UNA FALTA DE REGULACIONES? DE NUEVO LAS ENSEÑANZAS

Directory of Open Access Journals (Sweden)

Julio César Espinosa Rodríguez

2012-05-01

Full Text Available Resumen La intensificación de la crisis a nivel global, luego de la bancarrota de Lehman Brothers en septiembre del 2008, ha provocado que el actual entorno económico y financiero sea complicado para la economía mundial, el sector financiero a nivel global y para los bancos centrales. La actual crisis deriva de muchas causas; no obstante las principales son tres: primero, aspectos macroeconómicos; segundo, la inadecuada regulación de los entes encargados, y tercero, los reguladores estimularon el rápido crecimiento de los derivados en el mercado OTC. Abstract The amplification of the global financial crisis, following the bankruptcy of Lehman Brothers in September 2008, has made the present economic and financial environment a not easy time for the world economy, the global financial system and for central banks. There are many causes from the recent financial crisis. Main could be three. First, there were macroeconomic components. Second, the inadequate oversight/regulation provided by financial market regulators. And third, federal regulators have actively encouraged the rapid growth of over-the-counter (OTC derivatives and securities by all types of financial institutions.

 Hypertelorism in Charcot-Marie-Tooth disease 1A from the common PMP22 duplication: A Case Report

Directory of Open Access Journals (Sweden)

Josef Finsterer

2012-03-01

Full Text Available  The 1.4Mb tandem-duplication in the PMP22 gene at 17p11.2 usually manifests as hereditary sensorimotor polyneuropathy with foot deformity, sensorineural hearing-loss, moderate developmental delay, and gait disturbance. Hypertelorism and marked phenotypic variability within a single family has not been reported. In a single family, the PMP22 tandem-duplication manifested as short stature, sensorimotor polyneuropathy, tremor, ataxia, sensorineural hearing-loss, and hypothyroidism in the 27 years-old index case, as mild facial dysmorphism, muscle cramps, tinnitus, intention tremor, bradydiadochokinesia, and sensorimotor polyneuropathy in the 31 year-old half-brother of the index-patient, and as sensorimotor polyneuropathy and foot deformityin the father of the two. The half-brother additionally presented with hypertelorism, not previously reported in PMP22tandem-duplication carriers. The presented cases show that the tandem-duplication 17p11.2 may present with marked intra-familialphenotype variability and that mild facial dysmorphism with stuck-out ears and hypertelorism may be a rare phenotypic feature of this mutation. The causal relation between facial dysmorphism and the PMP22 tandem-duplication, however, remains speculative.

U.S. Centennial of Flight Commision: Born of Dreams - Inspired by Freedom

Science.gov (United States)

2004-01-01

The U.S. Centennial of Flight Commission developed and maintained a public web site that included activities related to the centennial of flight celebration and the history of aviation. The web site, www.centennialofflight.gov, was continually updated with educational and historical information, events, sights and sounds, and Commission information from its inception to June 2004. This DVD contains a 'snap shot' of the web site as of April 2004. The Web site on this DVD can be enjoyed without an Internet connection although in some places, you will be given links to online content. DVD content includes: 1) About the Commission - Information on the legislation, the Commissioners and Advisory Board members, news, the National Plans, meeting minutes and status reports; 2) Calendar of Events - A comprehensive list of activities, symposiums, exhibits, air shows, educational activities and more that took place through March 2004; 3) Wright Brothers History - The Library of Congress bibliography of Wright-related resources as well as the Chronology and Flight Log; the Brunsman articles; interactive learning modules from The Wright Experience; short informative essays and a series of links to other Wright brothers information sources. 4) History of Flight - Essays and images on the history of flight; 5) Sights and Sounds - Images, movies and special collections that capture the accomplishments of the Wright brothers and others who made significant contributions throughout the history of aviation and aerospace. As part of the NASA Art Program, a centennial song, 'Way Up There,' was commissioned; 6) Licensed Products - View collections of souvenirs and gift items to commemorate the 100th anniversary of the first powered flight; 7) Education - Resources that will help educators and their students celebrate 100 years of flight. Teachers can download Wright brothers posters and a Centennial of Flight bookmark, view live Web casts, and access an Educational Resources Center

Aggregation of deaths from ischaemic heart disease among first and second degree relatives of 108 males and 42 females with myocardial infarction

Energy Technology Data Exchange (ETDEWEB)

Thordarson, O; Fridriksson, S

1979-01-01

The occurrence of deaths due to ischaemic heart disease (IHD) among first and second degree relatives of coronary patients and among relatives of an equal number of matched controls was studied on the basis of death certificates. The propositi were 108 males and 42 females, who had developed myocardial infarction (MI), males before 65 years of age and females before 70. When compared with controls, a 1-1/2-fold higher death rate was found among first degree relatives of the propositi and a lower average age at death. The difference in death rate between second degree relatives was not significant, except for maternal brothers. When compared with the death rate due to IHD in the general population, the increase in risk to first degree relatives of propositi was nearly 3-fold over the expected value, and 1-1/2-fold to second degree relatives. The age of the propositi at onset of MI did not affect the risk to relatives, whereas sex-related influence was significant. To first degree relatives of male propositi the risk increase was up to 5-fold over the expected value. The risk increase was found to be greatest to first degree male relatives of female propositi, or over 7-fold to fathers and brothers. Mothers and sisters of both male and female propositi showed a 4 to 5 fold risk increase over the expected value. The risk increase to second degree relatives was 2-1/2-fold over the expected value to maternal brothers of male propositi and 4-fold to such brothers of female propositi. The relatives of controls showed a coronary mortality close to that of the general population. Familial clustering of coronary deaths was found in 8.7% of the families of the propositi and in 4.7% of the families of the controls. The findings of the present study indicate a substantial genetic component in the overall aetiology of IHD, which is more prominent in families of female propositi but hardly of a magnitude to warrant genetic counseling.

Pattern of family history in stone patients.

Science.gov (United States)

Marickar, Y M Fazil; Salim, Abiya; Vijay, Adarsh

2009-12-01

Genetic predisposition to urolithiasis is a much discussed topic. The objective of this paper is to identify the types of family members of proved urinary stone patients, who have a history of urinary stone formation. The study population consisted of 2,157 urinary stone patients interviewed in 2003-2007 in the urinary stone clinic. Family members with stone history were classified as group 1--first order single (one person in the immediate family-father, mother, siblings, or children), group 2--first order multiple (more than one member in the above group), group 3--second order single (one person in the blood relatives in family--grandparents, grandchildren, uncles, aunts, cousins, etc.) and group 4--second order multiple (more than one member in the above group). Of the 2,157 patients studied, 349 patients gave positive history of stone disease constituting 16.18%. Of these, 321 were males and 28 were females. Subdivision of the family members showed that 282 patients (80.80%) had single family member with stones and the rest 67 (19.20%) had multiple family members with history of stone disease. Group 1 which constituted one family member in the immediate family had 255 involvements (father: 88, mother: 16, brother: 135, sister: 2, son: 10, and daughter: 4); Group 2 with multiple members in the immediate family constituted 51 relatives; of these, father and brother combination was the most common with 35 occurrences. Group 3 with one person in the distant relatives in family namely grandparents, grand children, uncles, aunts, cousins, etc. constituted 27 occurrences and Group 4 with more than one member in the distant family constituted 16 occurrences. It is concluded that single family member involvement was more than multiple involvements. Males predominated. Stone occurrence was more in the immediate family members than distant relatives. Brothers formed the most common group to be involved with stone disease. Study of stone risk in the family members should

Nuns, Brothers, and the Religion and Stress Questionnaire.

Science.gov (United States)

Rayburn, Carole A.; And Others

Women have been entering into religious leadership positions in larger numbers, although the field is still male-dominated. Stress and strain of both men and women in the field of religion has been experienced from the impact of such change. In this study, Roman Catholic nuns, who have not been seen by their own church as clerical workers or even…

Brothers Grimm Bicentenntial: Blueprint for a Community Celebration.

Science.gov (United States)

Novak, Sigrid Scholtz

Faculty at McNeese State University (Louisiana) and local civic, educational, and cultural groups encouraged their community to commemorate the anniversary of the births of Jacob and Wilhelm Grimm, German scholars who recorded fairy tales, myths, legends, and folk songs that are now an important part of the western world's cultural heritage,…

Our Brother's Keeper: The Indian in White America.

Science.gov (United States)

Cahn, Edgar S., Ed.; Hearne, David W., Ed.

The text describes the American Indian's frustrations with his closed world, which thwarts and penalizes individual and tribal self-realization, which rewards and perpetrates dependency, and which demands alienation from one's heritage as a price for survival. American society is described as arrogant and as attempting to insure that by systematic…

Big Brother Is Watching: Video Surveillance on Buses

Science.gov (United States)

Sloggett, Joel

2009-01-01

Many school districts in North America have adopted policies to permit cameras on their properties and, when needed, on buses used to transport students. With regard to school buses, the camera is typically a tool for gathering information to monitor behavior or to help investigate a complaint about behavior. If a picture is worth a thousand…

French physicist's brother denies links to Al Qaeda

CERN Multimedia

Overbye, Dennis

2009-01-01

"Days after the French authorities placed a physicist working in Switzerland under formal investigation in a terror case, a portrait of the man and his work has begun to emerge from interviews with officials and his lawyer"

Vennalik maja = A Brotherly House / Liina Jänes

Index Scriptorium Estoniae

Jänes, Liina, 1977-

2002-01-01

2001. a. Tallinnas Pirita teel valminud eramu projekteeris Arhitektibüroo Emil Urbel. Arhitektid Emil Urbel ja Indrek Erm, sisearhitekt Taso Mähar. Konstruktsioonid: E-Inseneribüroo. 5 ill.: korruste plaanid, sisevaade, välisvaated

Uued heliplaadid / Koit Raudsepp

Index Scriptorium Estoniae

Raudsepp, Koit

1999-01-01

Uute heliplaatide tutvustus : Peshay "Miles From Home", kogumik "Essential Selection Presents Human Traffic", Great White "Can"t Get There From Here", Ratt "Ratt", RZA "The RZA Hits", Insane Clown Posse "The Amazing Jackal Brothers"

20 CFR 410.623 - Reconsideration; right to reconsideration.

Science.gov (United States)

2010-04-01

... AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Determinations of Disability, Other... reconsideration is filed, as provided in § 410.624, by an individual as a widow, child, parent, brother, sister...

What Is Cardiomyopathy?

Science.gov (United States)

... underlying conditions, such as diabetes and high blood pressure . Cardiomyopathy often runs in families. Your doctor may suggest that your parents, brothers and sisters, and children get checked to see whether they have the ...

Establishing a learned-helplessness effect paradigm in C57BL/6 mice: behavioural evidence for emotional, motivational and cognitive effects of aversive uncontrollability per se.

Science.gov (United States)

Pryce, Christopher R; Azzinnari, Damiano; Sigrist, Hannes; Gschwind, Tilo; Lesch, Klaus-Peter; Seifritz, Erich

2012-01-01

Uncontrollability of major life events has been proposed to be central to depression onset and maintenance. The learned helplessness (LH) effect describes a deficit in terminating controllable aversive stimuli in individuals that experienced aversive stimuli as uncontrollable relative to individuals that experienced the same stimuli as controllable. The LH effect translates across species and therefore can provide an objective-valid readout in animal models of depression. Paradigms for a robust LH effect are established and currently applied in rat but there are few reports of prior and current study of the LH effect in mouse. This includes the C57BL/6 mouse, typically the strain of choice for application of molecular-genetic tools in pre-clinical depression research. The aims of this study were to develop a robust paradigm for the LH effect in BL/6 mice, provide evidence for underlying psychological processes, and study the effect of a depression-relevant genotype on the LH effect. The apparatus used for in/escapable electro-shock exposure and escape test was a two-way shuttle arena with continuous automated measurement of locomotion, compartment transfers, e-shock escapes, vertical activity and freezing. Brother-pairs of BL/6 mice were allocated to either escapable e-shocks (ES) or inescapable e-shocks (IS), with escape latencies of the ES brother used as e-shock durations for the IS brother. The standard two-way shuttle paradigm was modified: the central gate was replaced by a raised divider and e-shock escape required transfer to the distal part of the safe compartment. These refinements yielded reduced superstitious, pre-adaptive e-shock transfers in IS mice and thereby increased the LH effect. To obtain a robust LH effect in all brother pairs, pre-screening for minor between-brother ES differences was necessary and did not confound the LH effect. IS mice developed reduced motor responses to e-shock, consistent with a motivational deficit, and absence of a

Thyrotoxic periodic paralysis associated with a mutation in the sodium channel gene SCN4A.

Science.gov (United States)

Lane, Andrew H; Markarian, Katherine; Braziunene, Ieva

2004-12-01

Thyrotoxic hypokalemic periodic paralysis (THypoKPP) is an uncommon disorder with an unknown etiology. We describe a family in which the proband presented with paralysis and thyrotoxicosis. Because of similarities between familial hypokalemic periodic paralysis (FHypoKPP) and THypoKPP, we sequenced exon 12 of the SCN4A gene, which is known to be mutated in FHypoKPP. We identified an Arg672Ser mutation in the proband and his affected father, as well as the proband's brother. As the brother has paralysis without thyrotoxicosis, our finding suggests that the genetic spectrum of FHypoKPP and THypoKPP overlap. We speculate that thyroid hormone may exert a threshold or permissive effect in hypokalemic periodic paralysis. Non-thyrotoxic family members of individuals with THypoKPP may have an unrecognized risk for paralysis.

MED23-associated intellectual disability in a non-consanguineous family.

Science.gov (United States)

Trehan, Aditi; Brady, Jacqueline M; Maduro, Valerie; Bone, William P; Huang, Yan; Golas, Gretchen A; Kane, Megan S; Lee, Paul R; Thurm, Audrey; Gropman, Andrea L; Paul, Scott M; Vezina, Gilbert; Markello, Thomas C; Gahl, William A; Boerkoel, Cornelius F; Tifft, Cynthia J

2015-06-01

Intellectual disability (ID) is a heterogeneous condition arising from a variety of environmental and genetic factors. Among these causes are defects in transcriptional regulators. Herein, we report on two brothers in a nonconsanguineous family with novel compound heterozygous, disease-segregating mutations (NM_015979.3: [3656A > G];[4006C > T], NP_057063.2: [H1219R];[R1336X]) in MED23. This gene encodes a subunit of the Mediator complex that modulates the expression of RNA polymerase II-dependent genes. These brothers, who had profound ID, spasticity, congenital heart disease, brain abnormalities, and atypical electroencephalography, represent the first case of MED23-associated ID in a non-consanguineous family. They also expand upon the clinical features previously reported for mutations in this gene. © 2015 Wiley Periodicals, Inc.

Gunnar Aagaard Andersen: Commercial Design and Experimental Art

DEFF Research Database (Denmark)

Gether, Vibeke Petersen

2016-01-01

Gunnar Aagaard Andersen’s relaxed approach both to art and to commercialised creativity positioned him centrally in the field where the two overlap. Other important players were the brothers Aage and Mads Eg Damgaard, who owned textile factories in Herning, the artistic textile firm Unika Væv in ...... and total decoration. These developments within the visual arts of the 1950s and 1960s were followed up by Paul Gadegaard, Dieter Roth, Arthur Köpcke and Paul Gernes, as well as by Aagaard Andersen himself.......Gunnar Aagaard Andersen’s relaxed approach both to art and to commercialised creativity positioned him centrally in the field where the two overlap. Other important players were the brothers Aage and Mads Eg Damgaard, who owned textile factories in Herning, the artistic textile firm Unika Væv...

USA suurpanga krahh mõjutab siiski ka Eestit / Helga Koger

Index Scriptorium Estoniae

Koger, Helga, 1945-

2008-01-01

USA suuruselt neljas investeerimispank Lehman Brothers andis kohtusse avalduse pankrotimenetluseks. Endise Hansapanga juhatuse esimees Erkki Raasuke ei näe emapank Swedbanki positsioonidest tulenevalt Eesti või Balti pangandusega mingeid seoseid. Lisa: Lehmaniga seotud varad

Severe mental deficiency, proportionate dwarfism, and delayed sexual maturation. A distinct inherited syndrome.

Science.gov (United States)

Cantú, J M; Sánchez-Corona, J; García-Cruz, D; Fragoso, R

1980-01-01

Two 46,XY brothers were found to have a previously undescribed syndrome characterized by severe mental deficiency, proportionate dwarfism, and delayed sexual development. A recessive mode of inheritance, either autosomal or X-linked, is assumed.

Accommodative spasm in siblings: A unique finding

Directory of Open Access Journals (Sweden)

Rutstein Robert

2010-01-01

Full Text Available Accommodative spasm is a rare condition occurring in children, adolescents, and young adults. A familial tendency for this binocular vision disorder has not been reported. I describe accommodative spasm occurring in a brother and sister. Both children presented on the same day with complaints of headaches and blurred vision. Treatment included cycloplegia drops and bifocals. Siblings of patients having accommodative spasm should receive a detailed eye exam with emphasis on recognition of accommodative spasm.

Rome.The Etymological Origins

Directory of Open Access Journals (Sweden)

Enrique Cabrejas

2016-02-01

Full Text Available The name of Rome was always a great mystery. Through this taxonomic study of Greek and Latin language, Enrique Cabrejas gives us the keys and unpublished answers to understand the etymology of the name. For thousands of years never came to suspect, including about the founder Romulus the reasons for the name and of his brother Remus, plus the unknown place name of the Lazio of the Italian peninsula which housed the foundation of ancient Rome.

Stemcell Information: SKIP000843 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available GBA+/N370S 10001.197.01 10001.197.01 パーキンソン病 G20 Parkinson Disease 168600 ... 68 60-69 Male Ashkenazi J...ewish ... Ashkenazi Jewish ... Yes No Transgene-free iPS cells from Monozygotic twin brother of Parkinson Disease ....023 iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson...patient.Using CytoTune iPS Sendai reprogramming protocol (Life Technologies). パーキンソン

Traian Vuia – the Romanian inventor who first flew a powered airplane in 1906

Directory of Open Access Journals (Sweden)

Liviu FILIMON

2011-09-01

Full Text Available As observed the beginning of heavier than air devices started with Wright Brothers who flew in 1903 the first catapulted airplane equipped with an engine, similar to present motor gliders. In March 1906 took place the first flight of Vuia’s monoplane using on board installations. Since then a real competition between manufacturers has started to improve their airplanes as they become more efficient. Traian Vuia’s first flights and his beginnings are explained below.

Faith-Based Diplomacy: A Pathway to Marginalizing Al-Qa’ida

Science.gov (United States)

2013-03-01

contrast to the Islamist governments 12 that have risen to power since early 2011. The Muslim Brotherhood in Egypt , for example, has advocated a more...Zarqawi who had been misbehaving, and he says, brother, we notice from afar X, Y, and Z is happening. Based on our experience in Egypt and around the...theory: “Al Qaeda is not a traditional hierarchical organization, with a pyramid -style organizational structure, and it does not exercise full command

V cizích službách. Život a smrt pražského fundatisty

Czech Academy of Sciences Publication Activity Database

Freemanová, Michaela

2012-01-01

Roč. 31, - (2012), s. 317-327 ISSN 0231-7443 Institutional support: RVO:68378076 Keywords : Brothers Hospitallers' Hospital * boy Choristers * Prague * 18th Century * boy s and young men Subject RIV: AL - Art, Architecture, Cultural Heritage

Effect of resistance and aerobic exercises on bone mineral density ...

African Journals Online (AJOL)

Mohamed A. Eid

2014-01-07

: There was no significant difference between both groups in the ... ensure better quality of life in patients with hemophilia [5]. It .... placed under the affected knee joint and the child ..... New Delhi: Jaypee Brothers Medical Pub-.

76 FR 1402 - Notice of allocation of Tariff Rate Quotas (TRQ) on the Import of Certain Worsted Wool Fabrics...

Science.gov (United States)

2011-01-10

...--Rochester, NY, Elevee Custom Clothing--Van Nuys, CA, Retail Brand Alliance, Inc. d/b/a Brooks Brothers--New... provides that HTS 9902.51.16 is for the benefit of persons (including firms, corporations, or other legal...

An Assessment of New Applications for Single-Crystal Piezoelectric Materials

National Research Council Canada - National Science Library

Veitch, Lisa

1998-01-01

Piezoelectricity was first discovered by the Curie brothers in 1880. During the 1940s, piezoelectric ceramic materials were first used in commercial devices, and new materials and other applications have continued to develop over the years...

Multiple Sclerosis, Personal Stories | NIH MedlinePlus the Magazine

Science.gov (United States)

... of this page please turn Javascript on. Feature: Multiple Sclerosis Personal Stories: Nicole Lemelle, Iris Young, Michael Anthony, ... something quite different for a person living with multiple sclerosis, such as his girlfriend's brother, Chuy. The more ...

AFRREV IJAH, Vol.1 (4) November, 2012

African Journals Online (AJOL)

First Lady

This study examined the effects of self esteem, emotional health, and social competence .... They may also have telling consequences on the larger society in the areas ..... brothers and delinquency: Evaluating social influence during early and ...

20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.

Science.gov (United States)

2010-04-01

... determine your eligibility for SSI benefits beginning with the month in which your disability or blindness... deemed to Mr. Bert and Mr. Davis. Each of the brothers is liable for rent in the boarding house (a...

47 CFR 97.509 - Administering VE requirements.

Science.gov (United States)

2010-10-01

..., grandchildren, stepchildren, parents, grandparents, stepparents, brothers, sisters, stepbrothers, stepsisters... accommodate an examinee whose physical disabilities require a special examination procedure. The administering VEs may require a physician's certification indicating the nature of the disability before determining...

Rachel Jewkes

African Journals Online (AJOL)

different types of victims. Asked about motivations, men indicated that rape most commonly stemmed ... media campaigns such as 'Brothers for Life' and. 'One Man Can'. ..... of socialisation into a very violent, accentuated masculinity of a type.

Brain Aneurysm: Early Detection and Screening

Science.gov (United States)

... who has two or more relatives (e.g. mother, father, brother, sister, aunt, uncle, grandparent, cousins) with ... Harvey Memorial Chair of Research Kristen’s Legacy of Love Chair of Research TeamCindy Alcatraz Chair of Research ...

Childhood Leukemia

Science.gov (United States)

... acute types. Symptoms include Infections Fever Loss of appetite Tiredness Easy bruising or bleeding Swollen lymph nodes Night sweats Shortness of breath Pain in the bones or joints Risk factors for childhood leukemia include having a brother ...

Sõda ilma sentimentaalsuseta / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001

Sõjaromantikud said seriaali / Toomas Hiio

Index Scriptorium Estoniae

Hiio, Toomas, 1965-

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001

Plaadid : Pop & rock / Valner Valme

Index Scriptorium Estoniae

Valme, Valner, 1970-

2002-01-01

Uutest plaatidest Chemical Brothers "Come With Us", Air "Everybody Hetrz", "The Greatest Love Songs Ever", Nightlight Duo "Jäljed liival", closer To heaven ئ original Cast Recording, Sophie Ellis-Bextor "Read My Lips", Andreas Johnson "Deadly Happy"

Langenud Gorilla / Kertu Ruus

Index Scriptorium Estoniae

Ruus, Kertu, 1977-

2008-01-01

Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 8-9. USA investeerimispanga Lehman Brothers tegevjuhist Dick Fuldist. Vt. samas: Richard S. Fuld: CV; Ameerika unistuste täitja: vendade investeerimispank; Taust; Kommenteerivad: Madis Toomsalu ja Jonathan Well

Fabry's Disease: Case Series and Review of Literature

African Journals Online (AJOL)

Subsequent enzymatic and pedigree analysis confirmed the diagnosis of FD in the recipient and one of his brothers with the possibility of their mother ... enzyme levels and are being planned for treatment with enzyme replacement therapy ...

Combination of retinitis pigmentosa and hearing loss caused by a novel mutation in PRPH2 and a known mutation in GJB2: importance for differential diagnosis of Usher syndrome.

Science.gov (United States)

Fakin, Ana; Zupan, Andrej; Glavač, Damjan; Hawlina, Marko

2012-12-15

Purpose of this study was to molecularly characterize a family in which two brothers (46 and 36 years) presented with a combination of retinitis pigmentosa (RP) and severe sensorineural hearing loss while father and sister (71 and 41 years) presented with isolated RP. Retinal phenotype was compared with phenotype of 17 patients with Usher syndrome type 1. Ophthalmological examination included assessment of Snellen visual acuity, color vision with Ishihara tables, Goldmann perimetry (targets II/1-4) and microperimetry. Fundus autofluorescence imaging and optical coherence tomography were performed. Direct sequencing of all coding exons and flanking intronic sequences of GJB2 (gap junction protein, beta 2) and PRPH2 (peripherin 2) genes was performed in younger brother. Other family members were analyzed with sequencing (GJB2), high resolution melt analysis (GJB2) or restriction enzymes (PRPH2). Brothers with hearing loss were found to carry a homozygous c.35 delG mutation in GJB2, the most common mutation associated with recessive hearing loss. All patients were found to carry a novel heterozygous mutation c.389T>C (p.Leu130Pro) on PRPH2. Age of onset was higher in PRPH2 than USH1 patients, however with some overlap. Differentiation from retinal phenotype of USH1 could only be made in the oldest patient, who retained good central visual function after more than three decades of disease. Copyright © 2012 Elsevier Ltd. All rights reserved.

Isolated familial somatotropinomas: clinical features and analysis of the MEN1 gene.

Science.gov (United States)

De Menis, Ernesto; Prezant, Toni R

2002-01-01

Isolated familial somatotropinomas (IFS) rarely occurs in the absence of multiple endocrine neoplasia type I (MEN1) or the Carney complex. In the present study we report two Italian siblings affected by GH-secreting adenomas. There was no history of parental consanguinity. The sister presented at 18 years of age with secondary amenorrhea and acromegalic features and one of her two brothers presented with gigantism at the same age. Endocrinological investigations confirmed GH hypersecretion in both cases. Although a pituitary microadenoma was detected in both patients, transsphenoidal surgery was not successful. The sister received conventional radiotherapy and acromegaly is now considered controlled; the brother is being treated with octreotide LAR 30 mg monthly and the disease is considered clinically active. Patients, their parents and the unaffected brother underwent extensive evaluation, and no features of MEN1 or Carney complex were found. Analysis of polymorphic microsatellite markers from chromosome 11q13 (D11S599, D11S4945, D11S4939, D11S4938 and D11S987) showed that the acromegalic siblings had inherited different maternal chromosomes and shared the paternal chromosome. No pathogenic MEN1 sequence changes were detected by sequencing or dideoxy fingerprinting of the coding sequence (exons 2-10) and exon/intron junctions. Although mutations in the promoter, introns or untranslated regions of the MEN1 gene cannot be excluded, germline mutations within the coding region of this gene do not appear responsible for IFS in this family.

Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.

Science.gov (United States)

Vanderlaan, Doug P; Blanchard, Ray; Wood, Hayley; Zucker, Kenneth J

2014-01-01

In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect). In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768). Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.

Ethical Dilemma and Management of Infertility in HIV Seropositive ...

African Journals Online (AJOL)

aunts, uncles, sisters, brothers and in‑laws all work as a unit through life. Family relationships are guided by hierarchy and seniority. Individuals .... Nevertheless, the physician has to weigh the balance of the ... Ethical issues in professional life.

Anonymous letters? DNA and fingerprints technologies combined to solve a case.

Science.gov (United States)

Barbaro, A; Cormaci, P; Teatino, A; La Marca, A; Barbaro, A

2004-12-02

Two brothers, living in two different cities, received two different anonymous letters. We performed latent prints development and DNA research on the letters and also on a glass used by a cousin suspected to be the letters' sender.

I Remember Highlander

Science.gov (United States)

Williams-Hawkins, Maria

2016-01-01

"I Remember Highlander" reflects on the life choices of Marion Barry and Herman Henning Jr., fraternity brothers who sought the same goal but took different paths. The essay examines cultural and family situations that shaped lives and decisions.

Wright Flyer Project

Science.gov (United States)

2004-01-01

The wind tunnel test results have been published in the literature as summarized at the end of this report. As part of the education program, an introduction to engineering course module was designed and tested on 80 freshman engineering students at Old Dominion University. The five-week module required that five-person teams design, build and fly a radio-controlled airplane using only the wind tunnel data developed by the Wright brothers in 1902. That module is described in Sparks and Ash (2001). The Principal Investigator has co-authored one dozen publications resulting from this research, as listed at the end of this report. The Principal Investigator has given fourteen lectures on the Wright brother testing program and has appeared in two documentary television programs (summarized at the end of this report). Speaking invitations have continued since the completion of the project.

Walton: Building a Global Brand Through Internationalization

DEFF Research Database (Denmark)

Rana, Mohammad Bakhtiar; Tarikul Islam, Mohammad; Dholakia, Nikhilesh

and internationalisation in the generations that had followed him. Alam has led the internationalisation of the Walton brand since the creation of Walton in 2007, and its recent strategic expansion – the establishment of a subsidiary in Stuttgart, Germany – left him poised to expand Walton’s reach to both EU...... whether Walton could really compete with leading international brands, given its limited managerial talents and incremental innovation, and establish itself as a true global brand in near future. In early 2000, the management of RB group, comprising five brothers including Alam, realised......On August 28, 2015, Ashraful Alam, Managing Director of Rizvi and Brothers (the RB Group, precursor to Walton HIL) was flying from Dhaka to Frankfurt to attend the International Trade Fair. In the plane, he began thinking about his veteran grandfather, who had sown the seed of entrepreneurship...

Autism in siblings with autosomal dominant nocturnal frontal lobe epilepsy.

Science.gov (United States)

Miyajima, Tomoko; Kumada, Tomohiro; Saito, Keiko; Fujii, Tatsuya

2013-02-01

In 1999, Hirose et al. reported a Japanese family with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) associated with a neuronal nicotinic acetylcholine receptor α4 subunit mutation (S252L). We followed the siblings of this family, and found that the elder brother had Asperger's disorder without mental retardation (MR) and the younger brother had autistic disorder with profound MR. The clinical epileptic features of the siblings were very similar, and both had deficits in socialization, but their cognitive development differed markedly. It thus seems that epilepsy is the direct phenotype of the S252L mutation, whereas other various factors modulate the cognitive and social development. No patients with ADNFLE have previously been reported to have autism spectrum disorder or profound MR. Copyright © 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

James Blunt matuselaulude edetabeli tipus

Index Scriptorium Estoniae

2006-01-01

Bereavement Registeri andmetel Suurbritannias matustel tellitavate laulude edetabelis: James Blunt "Goodbye My Lover", Robbie Williams "Angels", Jennifer Warnes ja Bill Medley "I've Had the Time Of My Life", Elton John "Candle in the Wind", Righteous Brothers "Unchained Melody"

Мао без головы / Мэлор Стуруа

Index Scriptorium Estoniae

Стуруа, Мэлор, 1928-

2010-01-01

Hiina skulptoritest Gao Zhenist ja Gao Qiangist, kes esinevad kunstnikunime Gao Vennad (Gao Brothers) all. Vendade dissidentlikust loomingust, nende skulptuurist "Mao süü" (Mao's Guilt), mis kujutab diktaator Mao Zedongi põlvili ja eemaldatava-külgekruvitava peaga

Contribution to the Catalogue of the painter and illustrator John Vanderbank: Six new Oils with Scenes of The Quixote in the Museum of Pontevedra

Directory of Open Access Journals (Sweden)

María Ángeles Tilve Jar

2014-12-01

Full Text Available In the Museum of Pontevedra stands out a set of six pictures of small format that narrate scenes of the Quixote. Realized in oil on table, they are works of the Englishman painter and illustrator John Vanderbank (1694-1739. In those pictures he adapts some of the prints that himself designed to illustrate the edition of luxury of Miguel de Cervantes who, promoted by Lord Carteret and printed by the Tonson brothers, was realized in London in 1738.

Introduction

Directory of Open Access Journals (Sweden)

Alfred Hornung

2012-01-01

Full Text Available Forty years after the assassination of Dr. Martin Luther King, Jr., the charismatic leader of the civil rights movement, Barack H. Obama was elected the first African American president of the United States of America in 2008. Although U.S. Attorney General Robert Kennedy had predicted in 1961 that a black person could be president like his brother “in the next thirty or forty years,” nobody really expected this kind of victory to come true.

Talectomy for Equinovarus Deformity in Family Members with Hereditary Motor and Sensory Neuropathy Type I

Directory of Open Access Journals (Sweden)

Hristo Georgiev

2014-01-01

Full Text Available The treatment of severe rigid neurogenic clubfoot deformities still remains a challenging problem in modern paediatric orthopaedics. In those cases, in spite of being a palliative procedure, talectomy has been advocated for the correction of the deformity thus providing a stable plantigrade foot which allows pain-free walking with standard footwear. Herein, we present the results after talectomy in two patients (brother and sister affected by a hereditary motor and sensory neuropathy type I, with rigid severe pes equinovarus deformities.

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2006-01-01

Uutest heliplaatidest J.M.K.E. "mälestusi Eesti NSV-st", Infadels "We Are Not The Infadels", Babyshambles "Down In Albion", Rigmor Gustafsson "On My Way To You", Mary J. Blige "The Breakthrough", Beck "Guerolito", Scala & Kolacny Brothers "Grenzenlos"

12 CFR 212.2 - Definitions.

Science.gov (United States)

2010-01-01

... person whose management functions relate exclusively to the business of retail merchandising or... Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MANAGEMENT OFFICIAL... immediate family. “Immediate family” means spouse, mother, father, child, grandchild, sister, brother, or...

An unusual variant of Becker muscular dystrophy

NARCIS (Netherlands)

de Visser, M.; Bakker, E.; Defesche, J. C.; Bolhuis, P. A.; van Ommen, G. J.

1990-01-01

We report on 5 brothers with slowly progressive limbgirdle weakness. Calf hypertrophy was absent. The levels of creatine kinase, electromyography, and findings from a muscle biopsy specimen were compatible with muscular dystrophy. The propositus's biopsy specimen also showed numerous rimmed

Progressive cerebellar atrophy and polyneuropathy: expanding the spectrum of PNKP mutations

NARCIS (Netherlands)

Poulton, C.; Oegema, R.; Heijsman, D.; Hoogeboom, J.; Schot, R.; Stroink, H.; Willemsen, M.A.A.P.; Verheijen, F.W.; Spek, P. van der; Kremer, A.; Mancini, G.M.S.

2013-01-01

We present a neurodegenerative disorder starting in early childhood of two brothers consisting of severe progressive polyneuropathy, severe progressive cerebellar atrophy, microcephaly, mild epilepsy, and intellectual disability. The cause of this rare syndrome was found to be a homozygous mutation

Intellectual disability, muscle weakness and characteristic face in three siblings: A newly described recessive syndrome mapping to 3p24.3-p25.3

NARCIS (Netherlands)

Kariminejad, Ariana; Nafissi, Shahriar; Nilipoor, Yalda; Tavasoli, Alireza; van Veldhoven, Paul P.; Bonnard, Carine; Ng, Yeng Ting; Majoie, Charles B.; Reversade, Bruno; Hennekam, Raoul C.

2015-01-01

We report on a sister and two brothers born to healthy Iranian parents with mild intellectual disability, progressive muscle weakness, and characteristic facies. including highly arched eyebrows, down-slanting palpebral fissures, prominent nasal bridge, prominent nose, columella extending below alae

Pop / Lauri Tikerpe

Index Scriptorium Estoniae

Tikerpe, Lauri

2005-01-01

Heliplaatidest: Little Brother "The Minstrel Show", Jackson and his Computer Band "Smash", Matthew Herbert "Plat du Jour", Porn Sword Tobacco "Explains Freedom", Jamiroquai "Dynamite", Ryan Adams and the Cardinals "Jacksonville City Nights", The Dandy Warhols "Odditorium", Neil Young "Prairie Wind"

The debate on the structure of 1 John

African Journals Online (AJOL)

scholar's proposals for the different transitions of the main sections and .... a question of exact similarity but only 'a simple basic pattern that presumably ..... In his refutation of the claims of the opponents, the author states that faith and brotherly ...

Preschool Siblings of Handicapped Children--Impact of Peer Support and Training. Brief Report.

Science.gov (United States)

Lobato, Debra

1985-01-01

Six developmentally normal preschool siblings of disabled children participated in workshops in which modeling, rehearsal, and role play were used to improve siblings' understanding of disabilities while strengthening their self-perceptions and attitudes toward their disabled brother or sister. (Author/CL)

Cerebral, cerebellar, and colobomatous anomalies in three related males: Sex-linked inheritance in a newly recognized syndrome with features overlapping with Joubert syndrome

NARCIS (Netherlands)

Kroes, Hester Y.; Nievelstein, Rutger-Jan A. J.; Barth, Peter G.; Nikkels, Peter G. J.; Bergmann, Carsten; Gooskens, Rob H. J. M.; Visser, Gepke; van Amstel, Hans-Kristian Ploos; Beemer, Frits A.

2005-01-01

We present a so far unrecognized X-linked mental retardation syndrome with features overlapping with Joubert syndrome (JBS). Two brothers showed hypotonia, mental retardation, ocular abnormalities with impaired vision and colobomas and a breathing pattern compatible with JBS. Neuroimaging revealed

AHP 46: AN UNEXPECTED GIFT FROM THE GODS: BOYHOOD IN NORTHWEST CHINA

Directory of Open Access Journals (Sweden)

Yang Jialiang 杨佳亮

2017-04-01

Full Text Available My name is Chao. I'm an ordinary person from a poor mountain village in northwest China. Like most other human beings, I often ponder: Why do I exist? How should I live? What is the meaning of my life? I believe my life is not worthless. Everyone should be appreciated and each of us should be valued as a wonderful individual. This is why I wrote this book - to share with others the narrative of my life; to allow others to know another human being's life story. My parents had two children. Brother was born in 1982 and 10 years later in 1992, I was born. Mother was then 38 and Father was 42. I was an accident. My parents had decided to give me away because they were afraid of violating the one-child policy and because they were so poor. They had decided to give me to a rich family who would in return give them a truck. However, at that time Brother was very attached to me. He cried a lot when he heard that my parents would give me away. My parents then decided to keep me no matter the difficulties they faced.

JENIS TINDAK TUTUR YANG MENGIKUTI INTERJEKSI PANGGILAN DALAM BAHASA JEPANG

Directory of Open Access Journals (Sweden)

Maharani Patria Ratna

2016-03-01

Full Text Available [Types of Speech Acts Following Calling Interjection In Japanese] In speaking, there are times when a calling interjection can be followed by more than one type of speech acts. This research discusses the calling interjection which are used by male speakers in the film Brother Beat. In addition, this study also discussed what kind of speech acts that may follow the call in a speech interjection. The data in this study is a narrative that contains interjection calling spoken by male speakers in the Brother Beat movie. The method used is descriptive qualitative method. To get the data, the researcher usesscrutinize technique and tapping notes method. The results obtained in this research are, calling interjection, such as Anosa, oi, Anona, nee, you, and ano, are often used by male speakers to call the addressees. After the calling interjection, directive speech act and assertive speech act are speech act which appear to follow the calling interjection. Interjection ano sa, oi, anona, and ano, are types of calling interjection which can be followed by a directive speech acts and assertive speech act. In the other hand, calling interjection of nee, can be only  followed by a directive speech act, while calling interjection of you can be followed by a ssertives speech act.

Severe protein-calorie malnutrition in two brothers due to abuse by starvation

Directory of Open Access Journals (Sweden)

Marcela Montenegro Braga Barroso

Full Text Available Abstract Objective: To describe the case of two siblings with severe protein-calorie malnutrition due to abuse by starvation. Cases description: The two patients were simultaneously referred to the Hospital Municipal, where they were admitted to the Pediatric Gastroenterology clinic of a university hospital for diagnostic investigation of the cause of severe malnutrition and screening tests for Celiac Disease, Cystic Fibrosis and Environmental enteropathy among others. The exams were all normal, and after detailed research on the interactions of this family, we reached the conclusion that the malnutrition was due to abuse by starvation. The children spent approximately two months in the hospital, receiving a high-protein and high-calorie diet, with significant nutritional recovery. Comments: Abuse by starvation, although rare, should always be considered of as one of the causes of child malnutrition and pediatrician should be aware of the child's development, as well as the family interactions, to prevent more severe nutritional and emotional consequences in the future.

Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and early-onset liver cirrhosis in two siblings

NARCIS (Netherlands)

van Maldergem, L.; Tuerlinckx, D.; Wanders, R. J.; Vianey-Saban, C.; van Hoof, F.; Martin, J. J.; Fourneau, C.; Gillerot, Y.; Bachy, A.

2000-01-01

We present the clinical, pathological, biochemical, and molecular results on an infant girl with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency and data on her deceased elder brother for whom this condition was retrospectively diagnosed. Clinical signs were liver enlargement and

"Ce fut un véritable désastre"

CERN Multimedia

Parlange, Mary

2008-01-01

The Superconducting Supercollider would have to become the amercian big brother of the LHC, but the project was abandoned in 1993. Leon Lederman, one of its fathers and major figure of the particle physics, explains the reasons for this failure. (3 pages)

JPRS Report, Arms Control

Science.gov (United States)

1989-12-01

the current crisis." [passage omitted] In related developments, Presidential Chief-of-Staff Alberto Kohan disclosed yesterday that the Soviet gov...1989 The ABIMDE leaders, with four-star General Diogo Figueiredo, the youngest brother of former president Joao Figueiredo, in attendance, decided

Cryptography: It’s Not Just For Electronic Mail Anymore

Science.gov (United States)

1993-03-01

David Chaum . Security without identification: Transaction systems to make big brother obsolete. Communications of the ACM, 28(10): 1030-1044, Oc- tober...Jeannette Wing, Maurice Herlihy, Stewart Clamen, David Detlefs, Karen Kietzke, Richard Lerner, and Su-Yuen Ling. The Avalon language: A tutorial

Syphilis presenting as isolated cervical lymphadenopathy: two related cases.

NARCIS (Netherlands)

Crevel, R. van; Grefte, J.M.M.; Doorninck, D. van; Sturm, P.D.J.

2009-01-01

Two young adult brothers, with no apparent risk for sexually transmitted infections (STI), presented with unilateral cervical lymphadenitis. Syphilis was diagnosed by fine-needle aspiration cytology in one case, and subsequent serology and revision of a resected lymph node in the second case.

A dream come true

Indian Academy of Sciences (India)

Lawrence

family, had the responsibility of educating all his brothers and sis- ters and getting them ... try Mathematics in my pre-university instead of Physics Chemis- try Biology as I ... M.R.N. Murthy, an outstanding student in the Department of. Organic ...

Bernard of Clairvaux and the Cistercian Mystical Tradition

DEFF Research Database (Denmark)

McGuire, Brian Patrick

2013-01-01

Bernard of Clairvaux and the Cistercian mystical tradition; Bernard's hagiography, the Vita prima; Bernard, sharing with audience, perceptions of God's advent as the divine Word; Brothers of the New Monastery in 1098, less interest in the mystical; Medieval mystics and mystical traditions; Sensuous...

REVIEWS OF BOOKS : BOEKRESENSIFS

African Journals Online (AJOL)

adiposogenitale. In this monograph of 225 pages the brothers, doctors lnnocente and ... In the second part of the book certain physical changes noted by the authors ..... bative spirit in the American Forces in World War II and in Korea? To what ...

Intergenerational Solidarity and Support Between Adult Siblings

NARCIS (Netherlands)

Voorpostel, Marieke; Blieszner, Rosemary

2008-01-01

Using a Dutch national sample containing 1,259 triads (two siblings, one parent), we examined whether practical support and emotional support between siblings are enhanced by intergenerational solidarity and how this differs for brothers and sisters. Sibling support was affected by sibling dyad

Editorial Note Vol4 No1, June 2012 by Reginald M.J. Oduor

African Journals Online (AJOL)

RMJ Oduor

disparaged as “backward”, but other times lauded as “eco-friendly” or “cost- effective”. ... investigate the nature, scope and applicability of knowledge, to contribute towards a ... Luo widow and for the care of the home of one's deceased brother, ...

Download this PDF file

African Journals Online (AJOL)

2009-12-09

Dec 9, 2009 ... In modern-day South Africa, many believers base their argument that the state should reinstate the .... in Genesis 9:23–26, which is used to justify slavery. .... starting in Genesis 4 with a brother being murdered and the.

Progress of CRARL in 2011

Institute of Scientific and Technical Information of China (English)

无

2011-01-01

In 2011, the CRARL project mainly in commissioning phase, engineering staff in the leaders of support, in functional departments and the brother of unit under the assistance, under the leadership of general manager, by joint efforts to complete the main process equipment,

75 FR 9869 - Initiation of Administrative Review of the Antidumping Duty Order on Wooden Bedroom Furniture...

Science.gov (United States)

2010-03-04

... Plastic Co., Ltd.,* Jibson Industries, Ltd.,* Always Loyal International * Baigou Crafts Factory of... Faith Limited * Brother Furniture Manufacture Co., Ltd. * C.F. Kent Co., Inc. C.F. Kent Hospitality, Inc... Company Limited * Dongguan Chunsan Wood Products Co., Ltd.,* Trendex Industries Ltd.* [[Page 9872...

The Life and Work of Niels Bohr – A Brief Sketch

Indian Academy of Sciences (India)

IAS Admin

Niels Henrik David Bohr was born to affluent parents on. 7 October 1885 in ... two years older; while his brother Harald, to whom he was ... sions from a very young age. ... married on 1 August 1912, the beginning of a 50-year relationship.

Improving Outcomes in the Nigeria Healthcare Sector through Public ...

African Journals Online (AJOL)

DrNneka

for the provision of cost-effective health services;. • to ensure that all .... way above the 15% threshold beyond which household risk is pushed into poverty by .... existed in France as early as 1792 AD when the Perrier Brothers was granted a.

Supporting U.S. Stretegy for Third World Conflict

Science.gov (United States)

1988-06-01

Pablo Escobar-Gaviria, the Ochoa brothers, (Jorge, Fabio, and Juan), Jaime Guillot-Lara, and Carlos Lehder Rivas formed large, ocean and continent... Bonilla . Courageously, Colombia’s President Betancur and his congress legislated new, more rigorous legal strictures against illegal drug trafficking

RESONANCE

Indian Academy of Sciences (India)

The Wright brothers were from a low middle class family and their formal education did not go beyond high school, and though each spent the time for a ... concealed is his hands, and before we ... sublime disregard for science, at once dubbed ...

NASA aircraft technician Donte Warren completes placement of the first official U.S. Centennial of F

Science.gov (United States)

2002-01-01

NASA aircraft technician Donte Warren completes placement of the first official U.S. Centennial of Flight Commission logo on an aircraft. The honored recipient is NASA Dryden Flight Research Center's Active Aeroelastic Wing (AAW) F/A-18 research aircraft, which is poised to begin wing-warping research flights harkening back to the Wright brothers. The Centennial of Flight Commission was created by the U.S.Congress in 1999 to serve as a national and international source of information about activities to commemorate the centennial of the Wright Brothers' first powered flight on the sands of Kitty Hawk, North Carolina, on December 17, 1903. Centennial activities are scheduled for 2003 in both North Carolina and Dayton, Ohio, home of the Wrights. In addition to these celebrations, numerous historical and educational projects are anticipated on the subject of aviation and aeronautics that will be an important legacy of the centennial of powered flight.

NASA aircraft technician Don Herman completes placement of the first official U.S. Centennial of Fli

Science.gov (United States)

2002-01-01

NASA aircraft technician Don Herman completes placement of the first official U.S. Centennial of Flight Commission logo on an aircraft. The honored recipient is NASA Dryden Flight Research Center's Active Aeroelastic Wing (AAW) F/A-18 research aircraft, which is poised to begin wing-warping research flights harkening back to the Wright brothers. The Centennial of Flight Commission was created by the U.S.Congress in 1999 to serve as a national and international source of information about activities to commemorate the centennial of the Wright Brothers' first powered flight on the sands of Kitty Hawk, North Carolina, on December 17, 1903. Centennial activities are scheduled for 2003 in both North Carolina and Dayton, Ohio, home of the Wrights. In addition to these celebrations, numerous historical and educational projects are anticipated on the subject of aviation and aeronautics that will be an important legacy of the centennial of powered flight.

Cine club

CERN Document Server

Cine club

2017-01-01

Wednesday 22 November 2017 at 20:00 CERN Council Chamber Plato’s Academy (Akadimia Platonos) Directed by Filippos Tsitos Greece / Germany, 2009, 103 minutes Stavros, a Greek shopkeeper cares for his aging mother after a stroke. Pity that his worst fears slowly are realized: he might be Albanian instead of Greek! Feeding these fears are his mother's lapses into Albanian language, the disconcerting appearance of an Albanian brother of whom he was unaware, and his neighbor's dog who only barks at Albanians. Stavros and his "brother" gradually reach a tenuous rapprochement even as his Greek neighbors begin to shun him. The old lady's funeral offers opportunities for conflict and resolution in Stavros' tight-knit enclave even as the community rapidly changes around them. Original version Greek / Albanian; English subtitles   Wednesday 29 November 2017 at 20:00 CERN Council Chamber Chevalier Directed by Athina Rachel Tsangari Greece, 2015, 105 ...

Upset in response to a Sibling's partner's infidelities.

Science.gov (United States)

Michalski, Richard L; Shackelford, Todd K; Salmon, Catherine A

2007-03-01

Using data collected from people with at least one brother and one sister, and consistent with an evolutionary perspective, we find that older men and women (a) are more upset by a brother's partner's sexual infidelity than by her emotional infidelity and (b) are more upset by a sister's partner's emotional infidelity than by his sexual infidelity. There were no effects of participant sex or sex of in-law on upset over a sibling's partner's infidelities, but there was an effect of participant sex on reports of upset over one's own partner's infidelities. The results suggest that the key variable among older participants is the sex of the sibling or, correspondingly, the sex of the sibling's partner, as predicted from an evolutionary analysis of reproductive costs, and not the sex of the participant, as predicted from a socialization perspective. Discussion offers directions for future work on jealousy.

Is young fatherhood causally related to midlife mortality? A sibling fixed-effect study in Finland.

Science.gov (United States)

Einiö, Elina; Nisén, Jessica; Martikainen, Pekka

2015-11-01

Previous studies have shown that young fatherhood is associated with higher later-life mortality. It is unclear whether the association is credible, in the sense that mortality and young fatherhood appear to be associated because both are determined by family-related environmental, socioeconomic and genetic characteristics. We used a household-based 10% sample drawn from the 1950 Finnish census to estimate all-cause mortality of fathers born during 1940-1950. The fathers were followed from age 45 until death, or the end of age 54. We used a standard Cox model and a sibling fixed-effects Cox model to examine whether the effect of young fatherhood was independent of observed adulthood characteristics and unobserved early-life characteristics shared by brothers. Men who had their first child before the age of 22 or at ages 22-24 had higher mortality as compared with their brothers who had their first child at the median or mean age of 25-26. Men who had their first child later at ages 30-44 had lower mortality than their brothers who had a first child before the age of 25. The pattern of results from a standard model was similar to that obtained from a fixed-effects sibling model. The findings suggest a causal effect of young fatherhood on mortality and highlight the need to support young fathers in their family life to improve health behaviours and health. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Birth order and recalled childhood gender nonconformity in Samoan men and fa'afafine.

Science.gov (United States)

Semenyna, Scott W; VanderLaan, Doug P; Vasey, Paul L

2017-04-01

Having a greater than average number of older biological brothers is a robust correlate of male androphilia (i.e., sexual attraction and arousal to adult males). Previous investigations have sought to understand whether this fraternal birth order (FBO) effect is also systematically related to recalled indicators of childhood gender nonconformity (CGN). However, these investigations have relied on data from low-fertility Western populations in which expressions of femininity in male children are routinely stigmatized and consequently, suppressed. The present study examined the FBO effect (among other sibship characteristics) and recalled indicators of CGN in Samoa, a high-fertility population, whose members are relatively tolerant of male femininity. Indeed, Samoans identify feminine androphilic males as belonging to an alternative gender category, known locally as fa'afafine. The present study compared the sibship characteristics of 231 fa'afafine and 231 opposite-sex attracted men from Samoa, as well as how these characteristics related to recalled CGN. Results replicated the well-established FBO effect for predicting male sexual orientation, with each older brother increasing the odds of being androphilic by 21%. However, no relationship was found between the number of older brothers (or other siblings) a participant had and their recalled CGN. Although fa'afafine reported significantly more CGN than Samoan men, CGN did not mediate the FBO effect, nor did the FBO effect and CGN interact to predict male sexual orientation. These findings are consistent with previous studies suggesting that the FBO effect is associated with male sexual orientation, but not childhood female-typical gender expression among androphilic males. © 2017 Wiley Periodicals, Inc.

Brothers at War? Reflections on an Internecine Conflict between ...

African Journals Online (AJOL)

1999-01-08

Jan 8, 1999 ... by civil wars, inter-state wars, conventional wars and ethnic conflicts. ... Over the past three decades, the political conflicts in Africa resulted in humanitarian crises and ... management roles to regional and sub-regional organisations. ... the origins of this conflict, to be immediately followed by an analysis of ...

Familial Churg-Strauss Syndrome in a Sister and Brother.

Science.gov (United States)

Alyasin, Soheyla; Khoshkhui, Maryam; Amin, Reza

2015-06-01

Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis. It is characterized by asthma, allergic granulomatosis and vasculitis. This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid. In every asthmatic patient with prolonged fever, eosinophilia and multisystemic involvment, CSS should be considered.

Schooling for Humanity: When Big Brother Isn't Watching.

Science.gov (United States)

Solmitz, David O.

Most educational reform initiatives of the past 20 years are geared towards ensuring that the United States dominates the emerging global economy. What is lost in this rush to the top of the materialist heap is an education for the more enduring human values: creativity, intellectual development, care, social justice, and democracy. In this book,…

Telemonitoring in heart failure: Big Brother watching over you.

Science.gov (United States)

Dierckx, R; Pellicori, P; Cleland, J G F; Clark, A L

2015-01-01

Heart failure (HF) is a leading cause of hospitalisations in older people. Several strategies, supported by novel technologies, are now available to monitor patients' health from a distance. Although studies have suggested that remote monitoring may reduce HF hospitalisations and mortality, the study of different patient populations, the use of different monitoring technologies and the use of different endpoints limit the generalisability of the results of the clinical trials reported, so far. In this review, we discuss the existing home monitoring modalities, relevant trials and focus on future directions for telemonitoring.

Babbitt's Brothers & Sisters: Raising Ethical Issues in Business Literature.

Science.gov (United States)

Halpern, Jeanne W.

A college-level course in business literature is an ideal place to raise and discuss ethical issues. To be successful, a teacher of this course must engage student interest, help the students articulate and understand their own ethical attitudes, clarify the stance and artistry of the author, and refine student responses to ethical questions. When…

Hereditary Gigantism-the biblical giant Goliath and his brothers.

Science.gov (United States)

Donnelly, Deirdre E; Morrison, Patrick J

2014-05-01

The biblical giant Goliath has an identifiable family tree suggestive of autosomal dominant inheritance. We suggest that he had a hereditary pituitary disorder possibly due to the AIP gene, causing early onset and familial acromegaly or gigantism. We comment on the evidence within the scriptures for his other relatives including a relative with six digits and speculate on possible causes of the six digits. Recognition of a hereditary pituitary disorder in the biblical Goliath and his family sheds additional information on his and other family members' battles with David and his relatives.

Examining Big Brother's Purpose for Using Electronic Performance Monitoring

Science.gov (United States)

Bartels, Lynn K.; Nordstrom, Cynthia R.

2012-01-01

We examined whether the reason offered for electronic performance monitoring (EPM) influenced participants' performance, stress, motivation, and satisfaction. Participants performed a data-entry task in one of five experimental conditions. In one condition, participants were not electronically monitored. In the remaining conditions, participants…

Leisure Coast City : A comparative history of the urban leisure waterfront. Barcelona. Chicago. Buenos Aires. 1870-1930

NARCIS (Netherlands)

Martire, A.

2008-01-01

*** NOTIFICATION *** With reference to this thesis, I express my debt to Dr. Sonia Berjman’s numerous and pioneer publications on Buenos Aires landscape history, which were not only inspiring but also the basis of my analysis of Courtois, Bouvard, Thays, Carrasco brothers, Forestier and other

Sperm influences female hibernation success, survival and fitness in the bumble-bee Bombus terrestris

DEFF Research Database (Denmark)

Baer, Boris; Schmid-Hempel, Paul

2005-01-01

. Using the bumble-bee Bombus terrestris, we artificially inseminated queens (females) with sperm from one or several males and show that sire groups (groups of brother males) vary in their effects on queen hibernation survival, longevity and fitness. In addition, multiply inseminated queens always had...

Plaadisoovitus

Index Scriptorium Estoniae

2005-01-01

Uutest helisalvestistest Chemical Brothers "Push The Button", "Hedvig Hanson, Andre Maaker", Ashanti "Concrete Rose", "Brazilian Girls", Pain "Dancing With the Dead", Moby "Hotel", Damien Rice "O-b-sides", Jennifer Lopez "Rebirth", De-Phazz "Natural Take", "Arash", "Legends Of Rock'n'Roll", "Playboy: The Mansion

20 CFR 222.44 - Other relationship determinations for lump-sum payments.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Other relationship determinations for lump... THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister... have the relationships to the employee shown below for lump-sum payment purposes: (a) Grandchildren. A...

Sõjas nagu sõjas ikka / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001. Lühidalt ka teistest ilmasõda kajastavatest seriaalidest

First world war: 'The first big test of professional nursing'.

Science.gov (United States)

Trueland, Jennifer

2017-08-16

When Helen Fairchild, a young nurse in Pennsylvania, volunteered to take her skills to Europe in the first world war, she was glad to go but felt sorry for her mother. 'If she would only not worry so much', she wrote to her brother Ned.

Familial LCAT deficiency: from renal replacement to enzyme replacement

NARCIS (Netherlands)

Stoekenbroek, R. M.; van den Bergh Weerman, M. A.; Hovingh, G. K.; Potter van Loon, B. J.; Siegert, C. E. H.; Holleboom, A. G.

2013-01-01

Familial LCAT deficiency (FLD) is a recessive lipid disorder ultimately leading to end-stage renal disease (ESRD). We present two brothers with considerable variation in the age at which they developed ESRD. Kidney biopsies revealed both tubular and glomerular pathology. To date, no causal therapy

Research Article Special Issue

African Journals Online (AJOL)

2017-02-15

IbnAsir, 1989, vol.4, p.283) bin Qaset bin ... brother Mas'ud-bin Haritha to Medina the next year (IbnAsir, 1989, vol.4, p.284). Al-Kamil history has not ..... (1989), The News of Mecca and What Came from It, (translated by Mahmud.

The Use of Dynamic Segment Scoring for Language-Independent Question Answering

Science.gov (United States)

2001-01-01

initial window with one sentence is compared to scores corre- his/PRONOUN brother/ CONSANGUINITY like/SIMILARITY his/PRONOUN call/NOMENCLATURE he/PRONOUN...the query processing mod- ule. Using the differences between index numbers to specify phys- ical distance relationships among query keywords, we can

28 CFR 570.42 - Non-medical escorted trips.

Science.gov (United States)

2010-07-01

... member of an inmate's immediate family. For purposes of this rule, immediate family refers to mother, father, brother, sister, spouse, children, step-parents, and foster parents. (2) Non-emergency, non... persons (e.g., attending physician, hospital staff, funeral home staff, family members, U.S. Probation...

Download this PDF file

African Journals Online (AJOL)

Precious

from women and children to whom eku is supposed to be a mystery”. From all ..... possibility of their being half- brothers with different maternity, a condition that can ... omitted but he proceeded in the later pages of his work to itemize what he ...

Whole Exome Sequencing Reveals Compound Heterozygosity for Ethnically Distinct PEX7 Mutations Responsible for Rhizomelic Chondrodysplasia Punctata, Type 1

NARCIS (Netherlands)

Jacobsen, Jessie C.; Glamuzina, Emma; Taylor, Juliet; Swan, Brendan; Handisides, Shona; Wilson, Callum; Fietz, Michael; van Dijk, Tessa; Appelhof, Bart; Hill, Rosamund; Marks, Rosemary; Love, Donald R.; Robertson, Stephen P.; Snell, Russell G.; Lehnert, Klaus

2015-01-01

We describe two brothers who presented at birth with bone growth abnormalities, followed by development of increasingly severe intellectual and physical disability, growth restriction, epilepsy, and cerebellar and brain stem atrophy, but normal ocular phenotypes. Case 1 died at 19 years of age due

Understanding Immoral Conduct in Business Settings: A Behavioural Ethics Approach

NARCIS (Netherlands)

M.H. van Dijke (Marius)

2014-01-01

markdownabstract__Abstract__ In the past decades, the world has observed a large variety of business scandals, such as those at ENRON, WorldCom, AHOLD, Lehman Brothers, and News of the World. These scandals caused economic damage and undermined the trust that governments, shareholders, and

Learning Emotional Understanding and Emotion Regulation through Sibling Interaction

Science.gov (United States)

Kramer, Laurie

2014-01-01

Research Findings: Young children's relationships with their sisters and brothers offer unique and important opportunities for learning about emotions and developing emotional understanding. Through a critical analysis, this article examines sibling interaction in 3 different but normative contexts (conflict/conflict management, play, and…

An atypical case of Fanconi anemia in elderly sibs

NARCIS (Netherlands)

Kwee, ML; vanderKleij, JM; vanEssen, AJ; Begeer, JH; Joenje, H; Arwert, F; tenKate, LP

1997-01-01

We describe a 56-year-old woman suspected of Fanconi anemia on the basis of the following clinical findings: microcephaly, short stature, congenital deafness, and the clinical findings in her deceased brother. Hematologic or other signs of malignancy were absent. The diagnosis was confirmed by

77 FR 76148 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

Science.gov (United States)

2012-12-26

..., corporate debt securities are fixed-income securities issued by businesses to finance their operations....nyse.com , at the principal office of the Exchange, and at the Commission's Public Reference Room. II... principal underwriter and distributor of the Fund's Shares. Brown Brothers Harriman & Co. (``Administrator...

20 CFR 416.1231 - Burial spaces and certain funds set aside for burial expenses.

Science.gov (United States)

2010-04-01

... children and step-children; an individual's brothers, sisters, parents, adoptive parents, and the spouses... are set aside for the burial arrangements of the eligible child's ineligible parent or parent's spouse... separation; i.e., a circumstance beyond an individual's control which makes conversion/separation impossible...

Een eenmalige imaginaire exposuresessie tijdens een cursus: De rol van de omgeving en het ondernemen van actie

NARCIS (Netherlands)

Sieh, D.S.; Lange, A.

2007-01-01

A doctoral student in clinical psychology had been emotionally abused by his brother and sister for many years during his youth, without his parents interfering. He took a doctoral course in cognitive behavioral therapy. He volunteered to be subject in a demonstration of a one-session imaginary

food for thought: interpreting the parable of the loyal and wise slave

African Journals Online (AJOL)

42Who then is the faithful [and] wise slave whom the master put over his household to give [them] food on time? 43Blessed is that slave .... 2.2 Will you be able to manage? On the literal ..... God's plan to ensure the survival of Joseph's brothers.

20 CFR 222.41 - Determination of relationship and support for parent.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Determination of relationship and support for parent. 222.41 Section 222.41 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.41...

20 CFR 222.42 - When employee is contributing to support.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When employee is contributing to support. 222.42 Section 222.42 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.42 When...

20 CFR 222.43 - How the one-half support determination is made.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How the one-half support determination is made. 222.43 Section 222.43 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.43...

The Third Indochina Conflict: Cambodia’s Total War

Science.gov (United States)

2014-12-12

movement which sought to unify the efforts of the independence movements in Cambodia, Laos and Vietnam against the French.5 The Cambodian left-wing...of Cambodia, 2007). 32 Martin, Cambodia: A Shattered Society. 33 Nayan Chanda, Brother Enemy, 43. Nayan Chanda wrote that Mao Tse -tung understood...

Předtucha blížící se zkázy: předobraz druhé světové války v díle bratří Čapků. Volná interpretace filmového plakátu.

OpenAIRE

KOPÁČKOVÁ, Stanislava

2016-01-01

This thesis focuses on the work of the Čapeks Brothers and monitors their premonition of a coming destruction, the World War II. It consists of two parts theoretical and practical. The practical part presents poster set freely interpreting a Hugo Haas film The White Disease.

Sibling Sex Ratio and Birth Order in Early-Onset Gender Dysphoric Adolescents

NARCIS (Netherlands)

Schagen, S.E.E.; Delemarre-van de Waal, H.A.; Blanchard, R.; Cohen-Kettenis, P.T.

2012-01-01

Several sibship-related variables have been studied extensively in sexual orientation research, especially in men. Sibling sex ratio refers to the ratio of brothers to sisters in the aggregate sibships of a group of probands. Birth order refers to the probands' position (e.g., first-born,

76 FR 72410 - Proposed Agency Information Collection Activities: Comment Request

Science.gov (United States)

2011-11-23

... their balance sheets in the volatile period following the collapse of Lehman Brothers in the fall of...) control number. The Federal Financial Institutions Examination Council (FFIEC), of which the agencies [email protected] . Include the OMB control number in the subject line of the message. Fax: (202...

12 CFR 711.2 - Definitions.

Science.gov (United States)

2010-01-01

... immediate family. “Immediate family” means spouse, mother, father, child, grandchild, sister, brother, or... her immediate family, whose shares are necessary to constitute the group owns a nominal percentage of... family income for the metropolitan statistical area (MSA), if a depository organization is located in an...

Experiences of women living with borderline personality disorder

African Journals Online (AJOL)

N. Ntshingila

personality disorder, it was evident that there were childhood experiences of living in an ... problems, emotional upheaval, looking for emotional escape and having different trigger factors. Lastly ... to experience negative interactions with mental health care ..... parents divorced and so my brother wanted to stay with my dad.

To Fly in the Sky.

Science.gov (United States)

Brodie, Carolyn S.

1995-01-01

Suggests activities for students that focus on airplanes, famous pilots, and travel. Provides a list of suggested titles with the following topics: history of flight and airplanes; airplanes and flying information; paper and model airplanes; Charles Lindbergh; Amelia Earhart; the Wright Brothers; videos; and picture books. (AEF)

Global Interdependence and the Need for Social Stewardship. Paper No. 1.

Science.gov (United States)

Mazur, Laurie Ann; Sechler, Susan E.

On October 7-8, 1996, the Rockefeller Brothers Fund joined with the World Bank to host a gathering of foundation executives, leaders of major humanitarian and environmental nongovernmental organizations, and officers of large multilateral institutions. The meeting was entitled "Building a Constituency for Global Interdependence," and its…

[Freud in the journals of the German speaking exile].

Science.gov (United States)

May, Ulrike

2006-01-01

Freud and psychoanalysis figure frequently in exile journals. This paper documents two letters to the editor written by Alexander Freud who denied that his brother Sigmund had been a zionist, and the recollections of the sculptor Königsberger who had made a bust of Freud in 1920.

FBI hakkab Wall Streeti puistama / Heiki Suurkask

Index Scriptorium Estoniae

Suurkask, Heiki, 1972-

2008-01-01

FBI hakkab uurima nelja äsja hiigelkahjumeid kandnud suurfirmat - Fannie Mae, Freddie Mac, Lehman Brothers, AIG - võimaliku hüpoteegipettuse pärast. Hüpoteegikriisi pärast on uurimise all ka ligi 1400 individuaalset kinnisvaravahendajat. USA-s levivast kinnisvarapetuskeemist. Lisa: Kongress vaidleb triljonite üle

Ultrasound-triggered drug release from vibrating microbubbles

NARCIS (Netherlands)

Y. Luan (Ying)

2014-01-01

markdownabstract__Abstract__ Diagnostic medical ultrasound may have a slightly longer history than what you expected. Its root dates back to 1930s and 1940s, when Theodore Dussik, a psychiatrist and neurologist, and his brother Friederich used a 1.5 MHz source to record signal variations after

X-linked congenital panhypopituitarism.

Science.gov (United States)

Schimke, R N; Spaulding, J J; Hollowell, J G

1971-05-01

Two half brothers with panhypopituitary dwarfism are reported who have the same mother and different, unrelated fathers. The subject of hereditary panhypopituitarism is reviewed briefly. It is concluded that there are at least two forms of hereditary panhypopituitary dwarfism, one of which may be X-linked.

Finding Common Ground: Use of a Geographically-Framed Landscape Template as an Integrating Platform for an International Education Initiative

Science.gov (United States)

Brierley, Gary; Li, Xilai; Qiao, Youming; Huang, He Qing; Wang, Zhaoyin

2018-01-01

This situated case study outlines how a place-based landscape template provided an integrative platform for the environmental arm of a cross-disciplinary international education initiative, the Three Brothers Project, wherein geographers at the University of Auckland worked alongside engineers at Tsinghua University in Beijing to support…

Kontserdipeegel / Igor Garshnek

Index Scriptorium Estoniae

Garšnek, Igor, 1958-

2000-01-01

Kontsertidest Estonia kontserdisaalis ئ 17. veebr. ERSO A. Tshistjakovi juhatusel, solist S. Kuulmann; 28. veebr. Eesti-Soome SO A. Tali juhatusel kontserdiga "Armastus"; 2. märtsil ERSO A. Manzano juhatusel, solistid M. Mikalai, M. Männi ja P. Tarvas; 3. märtsil The Brass Brothers

Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: no association with neuroaxonal dystrophy?

NARCIS (Netherlands)

Bakker, H. D.; de Sonnaville, M. L.; Vreken, P.; Abeling, N. G.; Groener, J. E.; Keulemans, J. L.; van Diggelen, O. P.

2001-01-01

Two new individuals with alpha-NAGA deficiency are presented. The index patient, 3 years old, has congenital cataract, slight motor retardation and secondary demyelinisation. Screening of his sibs revealed an alpha-NAGA deficiency in his 7-year-old healthy brother who had no clinical or neurological

The Perspective of Young Adult Siblings of Individuals with Asperger Syndrome and High Functioning Autism: An Exploration of Grief and Implications for Developmental Transition

Science.gov (United States)

Allgood, Nicole R.

2010-01-01

Asperger syndrome (AS) and high functioning autism are complex developmental disabilities that have a significant impact on the individual and his/her family. Asperger syndrome is characterized by challenges with understanding non-verbal communication, difficulties with social relationships, and restricted interests. Having a brother or sister…

A rare case of familial reactive perforating collagenosis

Directory of Open Access Journals (Sweden)

Rajesh Verma

2013-01-01

Full Text Available A 4 year old boy presented with history of itchy raised lesions on body of 2 years duration. Though parental consanguinity was not present, his elder brother had similar complaints. Dermatological examination revealed multiple hyperpigmented papules with a central keratotic plug distributed mainly over face and extensors of upper and lower extremities. Koebnerisation was present. Skin biopsy revealed perforating collagen bundles in the upper dermis and epidermis which was confirmed by Van Gieson staining. Patient was being treated with topical retinoids and intralesional corticosteroids with minimal relief.

Fantasies of Valor: Legends of the Samurai in Japan and the United States

Directory of Open Access Journals (Sweden)

Mark Ravina

2010-10-01

Full Text Available I want to talk today broadly about Hollywood, its images of samurai and the Japanese, and how those images contrast with Japanese images of the samurai. But more narrowly, I want to talk about one particular film: the 2003 Warner Brothers film 'The Last Samurai, 'starring Tom Cruise. The reception of this film was so different in Japan and the United States that it seems as though the two audiences were watching two different movies. I think exploring those differences can provide substantial insight into cross-cultural perceptions.

Hypohidrotic Ectodermal, Dysplasia with Features of Acanthosis Nigricans and Chronic Candidiasis

Directory of Open Access Journals (Sweden)

Lalit Mohan

1985-01-01

Full Text Available Three siblings having hypohidrotic ectodermal dysplasia are described. In addition to trichodysplasia, odonto- dysplasia and they had acanthosis nigrilcans of the, ano-genitat area and lesions suggestive of candida infection as evidenced by chronic paronychia in the finger and toe-nail folds, and maceration in the groins.The youngest brother also had a cutaneous horn in the sacral region. Eyes showed a small interpalpebral fissure, myopia, dull foveal reflex and a convergent squint. Parents were non consanguinous. There was no demonstrable cell mediated immune defect.

Acción laboral, represión policial y asesinato en tiempos de régimen militar

Directory of Open Access Journals (Sweden)

Antonio Torres Montenegro

2013-01-01

Full Text Available This article analyses the assault suffered by a group of workers in 1972 in a sugar cane farm known as Las Matipurana, in the city of Escada, Pernambuco, Brasil. The main target of this violence were the brothers Luís Inocêncio Barreto, José Inocêncio Barreto y João Inocêncio Barreto, who were the leaders of la legal action against the farmer under the Labour Law. After winning the suit these workers were persecuted by the farmer and the police and military authorities.

Avant-propos

Directory of Open Access Journals (Sweden)

Naomi Wulf

2010-02-01

Full Text Available Depuis environ dix ans, les biographies des Pères fondateurs de la nation américaine connaissent un succès populaire sans doute inégalé dans le passé. Certaines sont l’œuvre de spécialistes universitaires de la jeune République américaine, tels Joseph J. Ellis avec Passionate Sage : The Character and Legacy of John Adams (1993, American Sphinx : The Character of Thomas Jefferson (1996, National Book Award, puis Founding Brothers : The Revolutionary Generation (2000, Prix Pulitzer et enfin ...

Hb D/Talassemia beta associada à anemia crônica Hb D/ Beta thalassaemia associated with chronic anaemia

Directory of Open Access Journals (Sweden)

Paulo C. Naoum

2002-03-01

Full Text Available We describe a case of Hb D/Beta thalassemia associated with chronic anemia. Hematological analyses performed in a patient with chronic anemia demonstrating microcytosis and hypochromic in his erythrocytes. Specific laboratory diagnosis performed by alkaline and acid electrophoresis, and fetal determination by alkali resistance, indicated it to be Hb D associated with beta thalassemia. Analyses carried out on his family (father, mother and brother confirmed the suspected diagnosis. Hb D/Beta thalassemia is a very rare interaction in the Brazilian population, and its determination required specific laboratorial techniques and hematological analyses.

Imbert-Vier Simon, Tracer des frontières à Djibouti : Des territoires et des hommes aux xixe et xxe siècles, Paris, Karthala, 2011, 479 pp. + 40 maps and plans + 9 graphs.

Directory of Open Access Journals (Sweden)

Shiferaw Bekele

2014-05-01

Full Text Available Suddenly, in 1998, the brotherly and friendly states of Eritrea and Ethiopia went into a bloody two-year war that stunned the world by its ferocity, the extent of human casualties and the destruction of resources. One of the root causes was the boundary between the two countries, which was never demarcated. But this was not the first boundary war in the troubled Horn of Africa. In 1964 and again in 1977-8, Somalia launched war on Ethiopia; the latter was massive and bloody. Much later, Eritre...

Myopathy associated with pigmentary degeneration of the retina and high protein content of cerebrospinal fluid Miopatia associada a degeneração pigmentar da retina e hiperproteinorraquia

Directory of Open Access Journals (Sweden)

José Antonio Levy

1974-06-01

Full Text Available The cases of two brothers suffering from a myopathy associated with pigmentary degeneration of the retina and increase of protein content of the cerebrospinal fluid are reported.Foram estudados dois pacientes, filhos de pais não consanguíneos, com quadro miopático, iniciado na segunda década da vida, com predomínio na musculatura das cinturas e da face. Em ambos os casos havia degeneração pigmentar da retina e aumento da taxa protéica no líquido cefalorraqueano.

Unusual Respiratory Manifestations in Two Young Adults with Duchenne Muscular Dystrophy

Directory of Open Access Journals (Sweden)

Julie Lemay

2012-01-01

Full Text Available Adult respirologists are often involved in the evaluation and treatment of young adult patients with Duchenne muscular dystrophy. In this context, the most frequent respiratory complication is nocturnal and daytime hypoventilation related to respiratory muscle weakness. The present article describes cases of Duchenne muscular dystrophy involving two brothers, 17 and 19 years of age, respectively, who presented with less frequently reported respiratory complications of their disease: obstructive sleep apnea and Cheyne-Stokes respiration with central apnea, which were believed to be partially or completely related to congestive cardiomyopathy.

Three steps to the Universe from the sun to black holes to the mystery of dark matter

CERN Document Server

Garfinkle, David

2009-01-01

If scientists can't touch the Sun, how do they know what it's made of? And if we can't see black holes, how can we be confident they exist? Gravitational physicist David Garfinkle and his brother, science fiction writer Richard Garfinkle, tackle these questions and more in Three Steps to the Universe, a tour through some of the most complex phenomena in the cosmos and an accessible exploration of how scientists acquire knowledge about the universe through observation, indirect detection, and theory. The authors begin by inviting readers to step away from the Earth and reconsider our Sun. What we can directly observe of this star is limited to its surface, but with the advent of telescopes and spectroscopy, scientists know more than ever about its physical characteristics, origins, and projected lifetime. From the Sun, the authors journey further out into space to explore black holes. The Garfinkle brothers explain that our understanding of these astronomical oddities began in theory, and growing mathematica...

The determination of the tribe of family members in Luhak Limopuluh Koto, West Sumatera Indonesia

Science.gov (United States)

Bahri, S.; Abbas, A.; Bakar, N. N.

2018-01-01

In this paper, some mathematical models that state the tribe of the family members in Nagari Luhak Limopuluh Koto West Sumatera, Indonesia were built. The models were constructed by using the marriage rule and the ethnic data of Minangkabau community which embrace the matrilineal system. The marriage rule prohibits the same inter-tribal marriage while the matrilineal system causes the mother, child, and sibling tribes to be equal. Therefore, the matrices formed by marriage rule, mother-son tribal relation, someone-his/her sibling tribal relation, and the transpose of the matrices, are used in matrix multiplication to obtain the tribal models. The models are consecutively A, AC’, (AC’)B, ((AC’)B)W’, ((AC’)B)C, ((AC’)B)W, ((AC’)W’ for Denai, Denai’s mother, the sister of Denai’s mother, the brother of Denai’s mother, the husband of Denai’s mother’s sister, the son of Denai’s mother’s sister, the wife of Denai’s mother’s brother, and the Denai’s father models.

Cine club

CERN Document Server

Cine club

2016-01-01

Wednesday 13 April 2016 at 20:00 CERN Council Chamber Mushrooming   Directed by Toomas Hussar Estonia, 2012, 93 minutes A journalist has gotten wind of corruption rumors involving a politician. On the day the journalist tries to contact him, he decides to go mushrooming with his wife. Original version Estonian; English subtitles Wednesday 20 April 2016 at 20:00 CERN Council Chamber Very Big Shot   Directed by Mir-Jean Bou Chaaya  Lebanon / Qatar, 2016, 107 minutes In partnership with FIFOG, le Festival International du Film Oriental de Genève Brothers Ziad and Joe run a small but lucrative drug dealing business out of their takeout pizzeria in one of Beirut's working class districts. With their youngest brother Jad about to be released from prison - where he was serving a sentence for a crime that Ziad had committed - Ziad plans to go straight by using their coke-peddling profits to open a restaurant. But Ziad's supplier, a powerful drug lord who is n...

Autosomal dominant Carvajal plus syndrome due to the novel desmoplakin mutation c.1678A > T (p.Ile560Phe).

Science.gov (United States)

Finsterer, Josef; Stöllberger, Claudia; Wollmann, Eva; Dertinger, Susanne; Laccone, Franco

2016-09-01

Carvajal syndrome is an autosomal dominant or autosomal recessive disorder, manifesting with dilated cardiomyopathy, woolly hair, and palmoplantar keratoma. Additional manifestations can be occasionally found. Carvajal syndrome may be due to mutations in the desmocollin-2, desmoplakin, or plakophilin-2 gene. We report a family with Carvajal syndrome which additionally presented with hypoacusis, noncompaction, recurrent pharyngeal infections, oligodontia, and recurrent diarrhoea. Father and brother were also affected and had died suddenly, the father despite implantation of a cardioverter defibrillator (ICD). Genetic studies revealed the novel pathogenic mutation c.1678A > T in the desmoplakin gene resulting in the amino acid change Ile to Phe at position 560 in the index case and her brother. The index case underwent ICD implantation recently. Phenotypic manifestations of Carvajal syndrome are even broader than so far anticipated, the number of mutations in the desmoplakin gene responsible for Carvajal syndrome is still increasing, and these patients require implantation of an ICD as soon as their diagnosis is established.

Birth weight and two possible types of maternal effects on male sexual orientation: a clinical study of children and adolescents referred to a Gender Identity Service.

Science.gov (United States)

VanderLaan, Doug P; Blanchard, Ray; Wood, Hayley; Garzon, Luisa C; Zucker, Kenneth J

2015-01-01

This study tested predictions regarding two hypothesized maternal immune responses influencing sexual orientation: one affecting homosexual males with high fraternal birth order and another affecting firstborn homosexual individuals whose mothers experience repeated miscarriage after the birth of the first child. Low birth weight was treated as a marker of possible exposure to a maternal immune response during gestation. Birth weight was examined relative to sibship characteristics in a clinical sample of youth (N = 1,722) classified as heterosexual or homosexual based on self-reported or probable sexual orientation. No female sexual orientation differences in birth weight were found. Homosexual, compared to heterosexual, males showed lower birth weight if they had one or more older brothers--and especially two or more older brothers--or if they were an only-child. These findings support the existence of two maternal immune responses influencing male sexual orientation and possibly also cross-gender behavior and identity. © 2014 Wiley Periodicals, Inc.

Mentor Social Capital, Individual Agency and Working-Class Student Learning Outcomes: Revisiting the Structure/Agency Dialectic

Science.gov (United States)

Lovett, Trevor William

2014-01-01

This investigation explores factors that contributed to the disparate learning identities of two white baby-boomer brothers from the same working-class family. The research, part of a broader phenomenological study into the influences of working-class masculinities and schooling offers an insight into the individual family members' differential…

The Early History of Protocells

DEFF Research Database (Denmark)

Hanczyc, Martin

2008-01-01

experiments such as the fermentation of sugar into ethanol (a biological process) by the nonliving yeast extracts of the Buchner brothers in 1897 further opened the door to exploration of the grey space that conceptually lies between chemistry and biology (Friedmann, 1997). Here I present a brief historical...

Educative Suffering? Dostoevsky as Teacher

Science.gov (United States)

Roberts, Peter

2014-01-01

Fyodor Dostoevsky ranks among the most accomplished and respected figures in the history of literature. Almost a century and a half after his death, the major works for which he has become known--"The Brothers Karamazov," "Crime and Punishment," Demons", and "The Idiot" (Dostoevsky 1991, 1993, 1994, 2001,…

Sperm length, sperm storage and mating system characteristics in bumblebees

DEFF Research Database (Denmark)

Baer, Boris; Schmid-Hempel, Paul; Høeg, Jens Thorvald

2003-01-01

-term storage of sperm, using three bumblebee species with different mating systems as models. We show that individual males produce only one size-class of sperm, but that sperm length is highly variable among brothers, among unrelated conspecific males, and among males of different species. Males of Bombus...

Flight to Freedom: One Family and the Story of the Underground Railroad.

Science.gov (United States)

Horton, James Oliver

2001-01-01

Offers historical information on the underground railroad, a secret organization that attempted to move slaves from bondage to freedom. Focuses on William Still, one of the most effective organizers of the underground railroad, and the story of his family. Addresses the reunion between Still and his brother Peter. (CMK)

Antonio Lopez: Fashion, Art, Sex & Disco

DEFF Research Database (Denmark)

Langkjær, Michael Alexander

2014-01-01

Book review. Roger Padilha and his brother Mauricio may already be familiar to some as the New York-based fashion publicists, creators of the fashion public relations agency MAO PR, and as authors of The Stephen Sprouse Book (Rizzoli, 2009). Antonio Lopez: Fashion, Art, Sex & Disco, their second...

Factors influencing eating attitudes in secondary- school girls in ...

African Journals Online (AJOL)

self-perception, which may influence eating attitudes. Design. ... attrtudes in a group at risk for the development of eating disorders. ... self-approval with regard to body image jn young adolescent girls has been ... The current study aimed to explore the relationship between .... 'others' to sisters, aunts/uncles and brothers.

Cenové skoky během finanční nejistoty: od intuice k regulační perspektivě

Czech Academy of Sciences Publication Activity Database

Hanousek, Jan; Novotný, J.

2014-01-01

Roč. 62, č. 1 (2014), s. 32-48 ISSN 0032-3233 R&D Projects: GA ČR(CZ) GA14-27047S Institutional support: RVO:67985998 Keywords : European emerging stock markets * Lehman Brothers * price jumps * financial crisis Subject RIV: AH - Economics Impact factor: 0.650, year: 2014

Financial institutions have owner-occupancy in a stranglehold : An explanation for the recession in the Dutch housing market

NARCIS (Netherlands)

Boelhouwer, P.J.

2014-01-01

Like many other West-European countries, the Dutch housing market fell into a depression since the fall of Lehman Brothers at the end of 2008 and the credit crunch started. After 2010, many housing markets in Europe recovered from the financial crisis and experienced growing house prices again. This

'And end history. And go to the stars': Terence McKenna and 2012

NARCIS (Netherlands)

Hanegraaff, W.J.; Cusack, C.M.; Hartney, C.

2010-01-01

Terence McKenna (1946-2000) was a central fi gure in the underground New Age culture mostly referred to as ‘psychedelic shamanism’. In a book published together with his brother Dennis (! e Invisible Landscape, 1975) he developed a grand macrohistorical theory called the ‘Eschaton Timewave’, which

Support for Teens When a Family Member has Cancer

Science.gov (United States)

When a parent, brother, or sister has been diagnosed with cancer, family members need extra support. Information to help teens learn how to cope, talk with family members, manage stress, and get support from counselors when a loved one has been diagnosed with, or is being treated for, cancer.