WorldWideScience

Sample records for brothers full brothers

  1. My Brother Warren.

    Science.gov (United States)

    Forbes, Eric

    1987-01-01

    The younger brother of a hyperactive, severely learning-disabled 21-year-old recounts his feelings regarding lack of parental attention, jealousy toward his older brother, embarrassment, and finally empathy for his older brother. (CB)

  2. Brothers in Arms:

    DEFF Research Database (Denmark)

    Vincent, Stéphanie; Bingley, Paul; Lundborg, Petter

    Family members tend to have similar labor market outcomes, but measuring the contribution of behavioral spillovers is difficult. To identify spillovers between brothers, we exploit Denmark’s largest random assignment – of young men to 8 months of military service – where service status of brother...

  3. Bilateral breast in brothers - abreast

    Directory of Open Access Journals (Sweden)

    Altamash Mohammed Yusuf Shaikh

    2013-01-01

    Full Text Available Gynecomastia is a common occurrence in pubertal age group, and is physiological in up to 65 percent of cases. When occurs in the family it should be investigated in order not to miss on a treatable etiology. Two brothers within the same family, presenting with bilateral gynecomastia of different causes and requiring different treatment are presented.

  4. "I Loved My Brother Infinitely…"

    Directory of Open Access Journals (Sweden)

    Pavel Fokin

    2014-12-01

    Full Text Available Abstract Literary heritage of Mikhail Mikhailovich Dostoevsky(1820-1864 is not very abundant and appeals to experts only. His personality is of much more importance for national and world culture. He was a friend and soul mate of his genius brother (almost coeval. Their relations were an essential element of the biography and spiritual identity of Fyodor Dostoevsky. Mikhail was the first and for many years the only interlocutor of F.M. Dostoevsky. His role as an addressee in Fyodor Dostoevsky’s letters cannot be underestimated either. Fyodor Dostoevsky regarded his brother not only as a friend but as a business partner too. Their most successful joint enterprise was publishing of the magazine “Time” (“Vremya” (1861–1863, whose initiator and owner became Mikhail Dostoevsky. After Мikhail’s death Fyodor took charge of his family that had both direct and indirect impact on his own lifestyle. The year 2014 was the 150th anniversary of Mikhail Dostoevsky’s death. In this regard, the State Literature Museum organized an exposition titled “I loved my brother infinitely...” in the F.M. Dostoevsky Museum-Apartment. It was the first exposition dedicated to the personality of Mikhail Dostoevsky and his literary heritage. A lot of exhibit items had never been exposed before.

  5. "I Loved My Brother Infinitely…"

    OpenAIRE

    Pavel Fokin

    2014-01-01

    Abstract Literary heritage of Mikhail Mikhailovich Dostoevsky(1820-1864) is not very abundant and appeals to experts only. His personality is of much more importance for national and world culture. He was a friend and soul mate of his genius brother (almost coeval). Their relations were an essential element of the biography and spiritual identity of Fyodor Dostoevsky. Mikhail was the first and for many years the only interlocutor of F.M. Dostoevsky. His role as an addressee in Fyodor Dosto...

  6. Scott Brothers Windows and Doors Information Sheet

    Science.gov (United States)

    Scott Brothers Windows and Doors (the Company) is located in Bridgeville, Pennsylvania. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Pittsburgh, Pennsylvania.

  7. Nature vs. nurture: two brothers with schizophrenia.

    Science.gov (United States)

    Keltner, N L; James, C A; Darling, R J; Findley, L S; Oliver, K

    2001-01-01

    The nature vs. nurture argument as it pertains to two brothers. To explore the synergistic effects of heritability and environment in the cases of two brothers with schizophrenia. Review of the literature and the authors' clinical experience. The nature vs. nurture dichotomy may not be as relevant as looking at the interaction between these two forces.

  8. 75 FR 80669 - Wright Brothers Day, 2010

    Science.gov (United States)

    2010-12-22

    ... curious minds eager to transform and advance the world around them. Just as the Wright brothers... making great progress in ushering in a new commercial space industry that can help boost our economy...

  9. Cerebrotendinous xanthomatosis: report of two Brazilian brothers.

    NARCIS (Netherlands)

    Lange, M.C.; Zetola, V.F.; Teive, H.; Scola, R.H.; Trentin, A.P.; Zavala, J.A.; Pereira, E.R.; Raskin, S.; Werneck, L.C.; Sistermans, E.A.

    2004-01-01

    Cerebrotendinous xanthomatosis is a treatable rare autossomal recessive disease characterized by lipid storage secondary to a sterol 27-hydroxylase deficiency in the formation of cholic and chenodeoxycholic acids. We describe two Brazilian brothers with cognitive impairement and chronic diarrhea.

  10. The Wright Brothers and their First Flight

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 12. The Wright Brothers and their First Flight. O N Ramesh. Article-in-a-Box Volume 8 Issue 12 December 2003 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/008/12/0003-0004 ...

  11. 78 FR 76969 - Wright Brothers Day, 2013

    Science.gov (United States)

    2013-12-19

    ... champion STEM education in their communities. As we remember the Wright brothers, let us not forget another... results. That is why my Administration is dedicated to improving education in the vital fields of science... underrepresented groups, and through Race to the Top, we are raising standards and making STEM education a priority...

  12. 76 FR 79019 - Wright Brothers Day, 2011

    Science.gov (United States)

    2011-12-20

    ... with earnings from their bicycle shop, gathering data on wing shape using a home-built wind tunnel and... the Wright brothers over a century ago. To reaffirm our role as the engine that drives science and..., must we press onward, exploring new frontiers of science, technology, and imagination in pursuit of a...

  13. Extramammary Paget′s disease in two brothers

    Directory of Open Access Journals (Sweden)

    Xiaoting Zhang

    2015-01-01

    Full Text Available Extramammary Paget′s disease (EMPD, which is considered to be an adenocarcinoma of the apocrine glands, is a rare, slow-growing neoplasm. The standard treatment for local EMPD is surgical resection, however, so far, no effective treatment is found for advanced EMPD. Trastuzumab, which is a recombinant monoclonal antibody against the human epidermal growth factor receptor 2 HER2 has been proved to be effective in the treatment of advanced EMPD in some cases where HER2 protein is overexpressed. Herein, we report two cases of EMPD in two brothers. The younger brother who presented as local EMPD on the scrotum received surgical resection and had no recurrence in 15 months following. The older brother suffered from invasive EMPD also on the scrotum with inguinal region multiple metastatic lymph nodes and was treated with combination chemotherapy and Trastuzumab to target HER2 consecutively after a wide surgical excision.

  14. Drs. Smith Brothers: dental surgeons of Calcutta.

    Science.gov (United States)

    Sanjeev, Kumar

    2014-01-01

    During the British raj, India attracted dental practitioners from all over the world who set up practices in the Presidency towns of Calcutta, Bombay, Madras and Bangalore. Lured by the abundant opportunity to make good money, these mercenary but courageous dentists counted Viceroys, Indian royalty and political leaders amongst their clients. Some, like the famous American Smith Brothers of Calcutta, were sought after even by the rulers of neighboring countries. Dr. Mark Smith's hazardous visit to the Amir of Afghanistan made worldwide headlines more than 100 years ago for the fabulous fee he was paid for the dental treatment. This paper briefly describes the exploits and experiences of the Smith brothers while in India.

  15. Correlation of WAIS IQ in 10 Pairs of Brothers.

    Science.gov (United States)

    Matarazzo, Joseph D.; And Others

    1978-01-01

    Pairs of brothers were individually examined with Wechsler Adult Intelligence Scale some 10 months apart by an experienced clinical psychologist unaware of the consanguineous relationship. Correlation of .42 for Full Scale IQ is consistent with median correlation reported by Erlenmeyer-Kimling and Jarvik in their 1963 literature review.…

  16. Five Martyr Brothers. First Polish hermits and their worship

    Directory of Open Access Journals (Sweden)

    Kinga Blaschke

    2016-12-01

    Full Text Available Brothers Benedict and John, students of Romuald, came to Poland at the invitation of Otto III to convert pagans. Soon the Italian hermits were joined by Polish brothers Isaac and Matthew, who helped them in learning the Slavic language. The hermits, as well as Christinus, well killed in 1003 by thugs who wanted to steal money given by Duke Boleslav to an expedition to Rome, which was aimed at obtaining papal consent for conducting missionary work. Although the hermits died as victims of a robbery, killed by fellow Christians, the pope canonized them as martyrs. Their lives are relatively well-documented: the earliest and the most credible story of the five brothers by Bruno of Querfurt was written as early as five years after their death, although remained unknown until 1883. Another early account is the life of St. Romuald by Piotr Damiani of 1041. The martyrs have been also associated with yet another mysterious work – a gravestone unearthed in 1959 at the external wall of the north Roman apse of the Gniezno Cathedral, considered by most researchers the oldest epigraphic item on the Polish soil. However, the identification of the warriors mentioned in the inscription with 11th century martyrs raises many doubts. The article discusses the above matters, as well as the subject of the development of the worship of the martyr brothers.

  17. Lecciones regulatorias de la quiebra de Lehman Brothers

    Directory of Open Access Journals (Sweden)

    William Black

    2010-09-01

    Full Text Available La quiebra de Lehman Brothers el 15 de septiembre de 2008 marcó un parteaguas en la actual crisis financiera/económica mundial. La decisión de las autoridades estadounidenses de no rescatar el banco ha sido objeto a un gran debate público y académico, pero casi siempre carente de una discusión a profundidad sobre el comportamiento del banco. William Black, un exregulador bancario reconocido por detectar los mayores fraudes durante la crisis bancaria de los Savings & Loan en los años ochenta en los Estados Unidos y uno de los criminólogo financiero más activos en la esfera pública estadounidense, ofrece al lector una visión de los negocios turbios de Lehman Brothers que le llevaron a su colapso. Con el respaldo de documentación pública, Black describe y analiza como Lehman Brothers actuaba como un “vector de fraude”, creando y recreando un ambiente criminal en el sector financiero que castiga al comportamiento honesto y premia el crimen financiero. Ese tema, central al entendimiento de la crisis, a la vez poco reconocido, se expone con la maestría de quien es uno de sus mejores conocedores.

  18. Brother Peter of Jesus at Purgatory: rewrites of a historiographyc passage

    Directory of Open Access Journals (Sweden)

    Joan Mahiques Climent

    2016-12-01

    Full Text Available The second volume of the Reforma de los descalzos (Madrid, 1655 of Brother Francis of St. Mary relates that Brother Peter of Jesus, while dying in Bellpuig because of the plague, appeared to a companion in Lleida to say he was in Purgatory. From different printed works and engravings published from 1681 to 1724, we study the relationship between texts and images representing this episode. We also edit two versions written by Brother John of St. Joseph (1642-1718, whose autographs are preserved in mss. 990 and 991 of the University of Barcelona Library.

  19. The Seven Brothers. The changing world of petrochemical multinationals

    International Nuclear Information System (INIS)

    Van Ammelrooij, A.

    2000-01-01

    Since the eighties oil companies do not build their own drilling installations and refineries, but contract out such construction activities to engineering contractors. An overview is given of the market of the so-called Seven Brother (analogue to Seven Sisters for the oil companies) and the changes that are taking place at the moment. The Seven Brothers are Asea Brown Boveri (USA), Fluor Corp (US), Kvaerner ASA (Norway), Foster Wheeler (UK), Jacobs (USA), Morrison Knudsen (USA), and Parsons (UK)

  20. Acral peeling skin syndrome: a case of two brothers.

    Science.gov (United States)

    Wakade, Oojwala; Adams, Beth; Shwayder, Tor

    2009-01-01

    We report two brothers of Middle Eastern descent with consanguineous parents who present with numerous fragile, flaccid blisters on the hands and feet. In addition to spontaneous peeling, they can manually peel skin from acral areas without pain. The symptoms worsen with warm temperatures, excessive water exposure, and perspiration. Two biopsies from flaccid blisters on the feet were taken from the older brother, which revealed cleavage at the level of the stratum corneum. A diagnosis of acral peeling skin syndrome was made.

  1. I Am My Brother’s Keeper: The Impact of a Brother2Brother Program on African American Men in College

    Directory of Open Access Journals (Sweden)

    Maristella Zell

    2011-08-01

    Full Text Available This qualitative study focuses on the perceived effects that Brother2Brother (B2B peer groups had on African American male college students in the Chicago area. Students’ perception of their educational and personal experiences, commitment to scholastic achievement, and integration into the campus environment were highlighted. Seven focus groups with members of B2B chapters yielded six themes: Academic Motivation, Personal Presentation, Validation of Emerging Skills, Personal Growth, Ethic of Collaboration, and Rewarded through Accountability. These themes demonstrated the importance of supporting the development of African American male collegians’ non-cognitive skills. Implications for educators and recommendations for higher education institutions are discussed.

  2. Biological versus nonbiological older brothers and men's sexual orientation.

    Science.gov (United States)

    Bogaert, Anthony F

    2006-07-11

    The most consistent biodemographic correlate of sexual orientation in men is the number of older brothers (fraternal birth order). The mechanism underlying this effect remains unknown. In this article, I provide a direct test pitting prenatal against postnatal (e.g., social/rearing) mechanisms. Four samples of homosexual and heterosexual men (total n = 944), including one sample of men raised in nonbiological and blended families (e.g., raised with half- or step-siblings or as adoptees) were studied. Only biological older brothers, and not any other sibling characteristic, including nonbiological older brothers, predicted men's sexual orientation, regardless of the amount of time reared with these siblings. These results strongly suggest a prenatal origin to the fraternal birth-order effect.

  3. Environmental behaviour of radioactivity from Chernobyl: Brothers Water study

    International Nuclear Information System (INIS)

    Bonnett, P.J.P.; Appleby, P.G.; Oldfield, F.; Haworth, E.Y.; Hilton, J.; Davison, W.

    1992-01-01

    A study has been carried out to examine the short term behaviour of Chernobyl derived radionuclides together with the longer term patterns of transport of weapons fallout derived 137 Cs first studied on the Brothers Water catchment in the English Lake District in the 1970's. Chernobyl derived radiocaesium is observable in the soils and lake sediments of the catchment. 210 Pb dating and diatom analysis were used to confirm that the lake sediments sampled were undisturbed. A simple box model is used to estimate radionuclide inventories in Brothers Water Lake sediments. Estimates derived using this model are reasonably consistent with estimates obtained from a variety of other sources. (author)

  4. Prolegomenon to the Study of "Brother" as a Male Family Role.

    Science.gov (United States)

    Arkin, William

    1979-01-01

    Directs the reader to sibling gender relationships. Patterns of intimacy in brother-brother and brother-sister relationships are identified. Masculine gender role patterns were expressed more frequently than classic sibling rivalry. Sisters, not mothers, were discovered to be the primary socializing agent for some of men's intimate relationships…

  5. 20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... entitlement to brother's benefits may be established for any month before January 1973, based on a disability... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Conditions of entitlement; parent, brother...; Duration of Entitlement; Filing of Claims and Evidence § 410.214 Conditions of entitlement; parent, brother...

  6. Commissioner for Inland Revenue v Lever Brothers and Unilever Ltd

    African Journals Online (AJOL)

    kirstam

    21Key words: Lever Brothers and Unilever; South African income tax; source of income; interest; the “practical man”; the .... facilities, and he housed his employees in a model village of well-built homes on the factory site. ... be cancelled and any excess of the value of the shares over the debt would be adjusted by a money.

  7. Commissioner for Inland Revenue V Lever Brothers and Unilever Ltd

    African Journals Online (AJOL)

    Lever Brothers, the South African tax case that formed the basis of this research, was concerned with determining the source of interest income. In its time, this was one of the landmark cases and established tax principles that were valid for 54 years, until superseded by changes to legislation. The research presented a ...

  8. Freud on Brothers and Sisters: A Neglected Topic

    Science.gov (United States)

    Sherwin-White, Susan

    2007-01-01

    This paper explores Freud's developing thought on brothers and sisters, and their importance in his psychoanalytical writings and clinical work. Freud's work on sibling psychology has been seriously undervalued. This paper aims to give due recognition to Freud's work in this area. (Contains 1 note.)

  9. Propaganda in Warner Brothers World War II Cartoons.

    Science.gov (United States)

    Machowski, James Stanley; Brown, James William

    To examine the role of the animated cartoon in propaganda associated with World War II, 194 of 262 cartoons produced for theatrical release by Warner Brothers, Inc., from 1939 to 1946 were analyzed. Propaganda content was determined by the number and nature of symbols used and the cartoon's "attitudes" toward these symbols. An analysis…

  10. Adult Sibling Relationships with Brothers and Sisters with Severe Disabilities

    Science.gov (United States)

    Rossetti, Zach; Hall, Sarah

    2015-01-01

    The purpose of this qualitative study was to examine perceptions of adult sibling relationships with a brother or sister with severe disabilities and the contexts affecting the relationships. Adult siblings without disabilities (N = 79) from 19 to 72 years of age completed an online survey with four open-ended questions about their relationship…

  11. Isolated Penile Torsion in Brothers: A Case Report

    Directory of Open Access Journals (Sweden)

    Metin Gunduz

    2012-04-01

    Full Text Available Penile torsion can be congenital and associated with hypospadias and chordee, or can be acquired after circumcision. The incidence of isolated neonatal penile torsion was 1.7 to 27% in the literature. The majority were between 10 and deg; and 20 and deg;. Generally, torsion was to the left in cases. The techniques for correction of penile torsion described in the literature are penile de-gloving and reattaching of skin, resection of Buck's fascia incising the base of the penis and removing angular ellipses of corporeal tissue with subsequent plication of tunica, and dorsal dartos flap rotation in severe cases. In conclusion, penile torsion may be familial. Therefore, brothers should be examined carefully. The degloving and realignment technique is successful in isolated penile torsion. [Arch Clin Exp Surg 2012; 1(2.000: 122-124

  12. Big Brother gør sit indtog

    DEFF Research Database (Denmark)

    Moeslund, Thomas B.

    2009-01-01

    På grund af frygten for terror er vi i dag parate til at acceptere en grad af overvågning, der før i tiden gav mindelser om George Orwells dystopi 1984. Teknisk er der dog betydelige udfordringer i at få IT-systemerne til at opføre sig som Big Brother. Udgivelsesdato: December......På grund af frygten for terror er vi i dag parate til at acceptere en grad af overvågning, der før i tiden gav mindelser om George Orwells dystopi 1984. Teknisk er der dog betydelige udfordringer i at få IT-systemerne til at opføre sig som Big Brother. Udgivelsesdato: December...

  13. Brothers with constrictive pericarditis – A novel mutation in a rare disease

    Directory of Open Access Journals (Sweden)

    Devendra V. Patil

    2016-09-01

    Full Text Available Familial constrictive pericarditis is extremely rare. We report a case of two brothers both suffering constrictive pericarditis along with having multiple painless joint deformities. Genetic workup confirmed the clinical diagnosis of camptodactyly-arthropathy-coxa vara-pericarditis (CACP syndrome CACP syndrome and also revealed a rare mutation in the causative gene.

  14. Living with a brother or sister with epilepsy: siblings' experiences.

    Science.gov (United States)

    Hames, Annette; Appleton, Richard

    2009-12-01

    There is conflicting evidence about the impact of disability upon siblings, and very little research on the siblings of children with epilepsy. There is some evidence that siblings who have less accurate information exhibit more distress. The aim of this study was to assess siblings' response to having a brother or sister with epilepsy and to begin to develop information for them. Parents of children attending paediatric neurology outpatient departments were invited to participate in a pilot study. Parents who consented to take part were asked if they had previously received information for siblings. Parents and siblings participated in a semi-structured interview and siblings were also invited to submit a personal account of living with a brother or sister who had epilepsy. Twenty-five families with a child with epilepsy aged 2.5-15 years initially agreed to take part. None of the families stated that they had ever seen or received any information specifically for siblings. Fourteen siblings from the 25 families, aged 8-25 years, provided a personal account of what it was like living with a brother or sister with epilepsy. Siblings' accounts included both negative and positive feelings, and specifically feelings of care and love for their sibling. This initial study suggests that siblings of children with epilepsy have many positive but also early negative feelings. The results are limited by the size of the study, the fact that most siblings were older sisters, and the mean time since diagnosis was 6 years. Finally, it is hoped that the personal accounts collected in this study will be published for the benefit of other siblings of children with epilepsy.

  15. Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.

    Science.gov (United States)

    Aydin, Halil Ibrahim

    2018-01-15

    Creatine transporter deficiency (CTD) is a treatable, X-linked, inborn error of metabolism. Two brothers with autism spectrum disorder were diagnosed with CTD at the ages of 17 and 12 years. Both were found to have a previously reported hemizygous p.408delF (c.1216_1218delTTC) deletion mutation. Both patients were given creatine monohydrate, L-arginine, L-glycine and S-adenosylmethionine, which partially improved the behavioral problems. Serum creatinine levels, creatine peak at brain MR spectroscopy or creatine/creatinine ratio in urine should be evaluated to identify CTD in children with autistic behavior and language disorders.

  16. WORKPLACE SURVEILLANCE: BIG BROTHER IS WATCHING YOU?

    Directory of Open Access Journals (Sweden)

    Corneliu BÎRSAN

    2018-05-01

    Full Text Available Only recently workplace surveillance has become a real concern of the international community. Very often we hear about employers who monitor and record the actions of their employees, in order to check for any breaches of company policies or procedures, to ensure that appropriate behaviour standards are being met and that company property, confidential information and intellectual property is not being damaged. Surveillance at workplace may include inter alia monitoring of telephone and internet use, opening of personal files stored on a professional computer, video surveillance. But what if this monitoring or recording breaches human rights? In order to give practical examples for these means, we shall proceed to a chronological analysis of the most relevant cases dealt by the European Court of Human Rights along the time, in which the Strasbourg judges decided that the measures taken by the employers exceed the limits given by Article 8 of the Convention. After providing the most relevant examples from the Court’s case-law in this field, we shall analyse the outcome of the recent Grand Chamber Barbulescu v. Romania judgment. The purpose of this study is to offer to the interested legal professionals and to the domestic authorities of the Member States the information in order to adequately protect the right of each individual to respect for his or her private life and correspondence under the European Convention on Human Rights.

  17. Little Brother Joins the Large Family

    Science.gov (United States)

    2006-12-01

    On the night of 15 December 2006, the fourth and last-to-be-installed VLTI Auxiliary Telescope (AT4) obtained its 'First Light'. The first images demonstrate that AT4 will be able to deliver the excellent image quality already delivered by the first three ATs. It will soon join its siblings to perform routinely interferometric measurements. ESO PR Photo 51a/06 ESO PR Photo 51a/06 VLT Auxiliary Telescope The VLT is composed of four 8.2-m Unit Telescope (Antu, Kueyen, Melipal and Yepun). They have been progressively put into service together with a vast suite of the most advanced astronomical instruments and are operated every night in the year. Contrary to other large astronomical telescopes, the VLT was designed from the beginning with the use of interferometry as a major goal. The VLT Interferometer (VLTI) combines starlight captured by two or three 8.2- VLT Unit Telescopes, dramatically increasing the spatial resolution and showing fine details of a large variety of celestial objects. ESO PR Photo 51b/06 ESO PR Photo 51b/06 One AT Under the Sky However, most of the time the large telescopes are used for other research purposes. They are therefore only available for interferometric observations during a limited number of nights every year. Thus, in order to exploit the VLTI each night and to achieve the full potential of this unique setup, some other (smaller), dedicated telescopes were included into the overall VLT concept. These telescopes, known as the VLTI Auxiliary Telescopes (ATs), are mounted on tracks and can be placed at precisely defined "parking" observing positions on the observatory platform. From these positions, their light beams are fed into the same common focal point via a complex system of reflecting mirrors mounted in an underground system of tunnels. The Auxiliary Telescopes are real technological jewels. They are placed in ultra-compact enclosures, complete with all necessary electronics, an air conditioning system and cooling liquid for

  18. Laryngologist Leon Zamenhof--brother of Dr. Esperanto.

    Science.gov (United States)

    Wincewicz, Andrzej; Sulkowska, Mariola; Musiatowicz, Marcin; Sulkowski, Stanislaw

    2009-06-01

    To reconstruct the biography of the Polish otorhinolaryngologist Leon Zamenhof (1875-1934), a brother of Ludwik Zamenhof, who is famous for invention of the international language Esperanto. Biographical information was collected from pre-World War II resources. Zamenhof developed several important new forms of treatment to help the hearing impaired. Zamenhof was especially interested in the education of deaf children and the therapy necessary to facilitate their integration into society. His significant achievements were a phonetic method of therapy for the hearing impaired and an automatic device for ear insufflation that was considered indispensable in the management of pyorrhea. In addition, Zamenhof initiated various forms of social support among physicians within the medical community of Warsaw, Poland; made health care available to children with hearing impairments; and organized a Jewish school for deaf children. Zamenhof tried to change public attitudes toward deafness, working to promote the integration of the deaf into wider society. He also translated Polish literature into Esperanto. With similar aims to his brother Ludwik, Leon Zamenhof strived to enhance and broaden communication among people who could not hear and to persuade people to change their attitudes about deafness.

  19. 75 FR 46864 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2010-08-04

    ...-0225; Directorate Identifier 2009-NM-203-AD] RIN 2120-AA64 Airworthiness Directives; Short Brothers PLC... this proposed AD, contact Short Brothers PLC, Airworthiness, P.O. Box 241, Airport Road, Belfast, BT3... amend this proposed AD based on those comments. We will post all comments we receive, without change, to...

  20. The Perceptions and Experiences of Adolescent Siblings Who Have a Brother with Autism Spectrum Disorder

    Science.gov (United States)

    Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Reilly, Deirdre; Dowey, Alan

    2012-01-01

    Background: There is a dearth of research on the perspectives of adolescent siblings growing up with a brother or sister with an autism spectrum disorder (ASD). Method: Semistructured interviews were used to elicit the perceptions and experiences of 12 typically developing adolescents with a brother with an ASD. Interpretative phenomenological…

  1. 20 CFR 410.380 - Determination of dependency; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determination of dependency; parent, brother... MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.380 Determination of dependency; parent, brother, or sister. An individual who is the miner's...

  2. 20 CFR 725.225 - Determination of dependency; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...

  3. Living with a Brother Who Has an Autism Spectrum Disorder: A Sister's Perspective

    Science.gov (United States)

    Connell, Zara O.; Halloran, Maeve O.; Doody, Owen

    2016-01-01

    People with Autism Spectrum Disorder (ASD) are born into families and influence family functioning both positively and negatively. One of the most enduring relationships a person with ASD will have is their relationship with a brother or sister. Services for people with ASD should provide effective support to families, which include brothers,…

  4. Discussing the Life of the Others: Doing Ethnography in the Brazilian Big Brother Fan Community

    Directory of Open Access Journals (Sweden)

    Bruno Campanella

    2009-05-01

    Full Text Available The aim of this paper is to present some of the initial results of ethnographic research conducted in early 2008 with the online fan community of the Brazilian Big Brother (BBB. After a brief introduction to some of the challenges faced by ethnographic work on television audiences in the last couple of decades, the current piece will explore some of the main characteristics constituting this new social space. Beyond the gossiping, and the more immediate talks about behaviors and game strategies of the Big Brother housemates, these forums sometimes trigger exchanges about Brazilian society at large, and the role of television broadcasting in general. Nonetheless, a closer inspection reveals how the debates found in the community are themselves permeated by the participants' struggle for status.

  5. KAKO PREDŠKOLSKA DJECA VIDE "BIG BROTHER" SHOW?

    OpenAIRE

    Janković, Andrea; Sindik, Joško; Jaman, Kamea

    2007-01-01

    Cilj istraživanja bio je ispitivanje nekih karakteristika gledanosti Big Brother show-a kod djece predškolske dobi, razloga gledanja te emisije, s aspekta preferiranih sadržaja emisije te ličnosti (kandidata) koje preferiraju djeca. Ispitan je prigodni uzorak djece srednje i starije vrtićke dobi iz 3 dječja vrtića iz Zagreba (Dječjeg vrtića Grigora Viteza i Dječjeg vrtića "Maksimir" i "Trnoružica", N = 142). Utvrđene su čestine razloga preferencije pojedinih sudionika show–a te pojedinih s...

  6. What Is That Song? : Aleksej Balabanov's Brother and Rock as Film Music in Russian Cinema

    OpenAIRE

    Österberg, Ira

    2018-01-01

    This dissertation examines the role of rock songs as film music in Russian cinema and how one important film, Aleksej Balabanov’s Brother (Brat, 1997), reshaped film music conventions in the 1990s. The study is divided into two sections: the first is a historical examination of more than twenty films made between the late 1920s and the early 1990s, the second focuses on Brother and its use of music. The research questions are 1) How is music used in Brother? 2) How were rock songs used in...

  7. Homozygous PARK7 Mutation in Parkinson’s Disease: Case Report of Two Brothers

    Directory of Open Access Journals (Sweden)

    Hülya Apaydın

    2008-06-01

    Full Text Available OBJECTIVE: Genetic studies for Parkinson’s disease (PD which have been increased during last few years have shown that parkin (PARK2, DJ-1 (PARK7 and PINK-1 (PARK6 mutations can cause autosomal recessive early-onset parkinsonism. OBJECTIVE: The aim of this study was to investigate by genetic screening methods, the presence of possible genetic mutations in two siblings who have developed PD. METHODS: In these two brothers, PD started at the age of 48 with cervical dystonia and bradykinesia on the left arm, and 56 with tremor on the right hand, respectively. Although they had a favorable response to levodopa, they developed wearing-off phenomenon without dyskinesia on the 4th year. Besides dystonia, the younger brother experienced psychosis and impulse control disorder, as well. Family history revealed first degree consanguinity and the father had also a diagnosis of PD. PD progressed rather slowly in both, but unfortunately the older brother died due to lung cancer 10 years after the initial diagnosis of PD, while he was on the stage 2 of Hoehn-Yahr scale. The younger brother is still on our follow-up at the 7th year of his PD. Informed consent was obtained and blood samples were sent to the genetic department of Juntendo University in Japan for genetic analysis. Parkin gene mutation and DJ-1 gene mutation were analyzed on the PARK7 locus, by automated direct nucleotide sequencing and performed gene dosage assay using TaqMan real-time quantitive PCR. RESULTS: After excluding the parkin mutation the presence of PARK7 was detected in both siblings with haplotype analysis. DJ-1 gene mutation analysis responsible for PARK7, revealed a deletion on intron 1. CONCLUSION: A rarely encountered PARK7 mutation was identified in two brothers having slowly progressive PD and a favorable response to levodopa, one of whom also had psychotic symptoms. As in the presented cases, the genetic studies performed on early-onset PD patients with positive family

  8. 20 CFR 410.340 - Determination of relationship; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... domiciled (see § 410.392) at the time of his death would find, under the law they would apply in determining..., brother, or sister. Where, under such law, the individual does not bear the relationship to the miner of...

  9. Do brothers and sisters of siblings with intelectual disability need the support of social work?

    OpenAIRE

    Cardová, Michaela

    2007-01-01

    This thesis explores the experience and support needs of siblings with a brother or sister with intellectual disability. Through review of what is a quite limited literature and from original qualitative research, involving interviews with siblings, the author examines their social reality, focusing especially on their relationships with their disabled brother or sister and with the wider society. Particular attention is given to identifying to what extent the siblings' lives are influenced b...

  10. The Montgolfier Brothers and the Invention of Aviation

    Science.gov (United States)

    Moore, Charles B.

    The first hot air balloon ascension over Paris in September 1783 has been described so many times that it and its passengers—the sheep, the rooster, and the duck—have joined Benjamin Franklin and his kite in the folklore of our culture. Not so well known is the earlier history of ballooning; that the brothers Montgolfier had demonstrated their hot air balloons repeatedly for several months prior to the ascent over Paris; or that the physicist Charles, urged onward and financed by an enthusiast, Barthélemy Faujas de Saint-Fond, launched successfully the first fabric balloon filled with hydrogen over Paris more than 3 weeks prior to the memorable ascent of the sheep, and rooster, and the duck.For all of its well-documented detail, the book is readable and enjoyable. It is a well-written but complex book in which Professor Gillispie develops a number of subjects to recreate the era in perspective. The origins and the disposition of the Montgolfiers, the industry of the period, the idea of capturing heated air are all reported in detail. The attempts to obtain government funding and the promotional activities in Paris were forerunners of the modern techniques for obtaining support of research activities.

  11. Career choices of migrant artists between Amsterdam and Antwerp. The Van Nieulandt brothers

    Directory of Open Access Journals (Sweden)

    Eric Jan Sluijter

    2015-12-01

    Full Text Available This essay examines the career choices of the brothers Guilliam II and Adriaen II van Nieulandt. Both were born in Antwerp but moved with their parents to Amsterdam at a young age. Guilliam returned to Antwerp to make his career, while Adriaen became embedded in Amsterdam’s artistic community. All members of their family – in Antwerp, Amsterdam and Rome – remained in close contact with each other, though changes in the religious and political culture left their mark on their professional decisions. Their choices did not yield artistic innovations but conservative styles and subjects based on shared Netherlandish traditions with a strong international flavour.

  12. Mortality and health-related habits in 900 Finnish former elite athletes and their brothers.

    Science.gov (United States)

    Kontro, Titta Katariina; Sarna, Seppo; Kaprio, Jaakko; Kujala, Urho M

    2018-01-01

    There is conflicting evidence on the associations between participation in vigorous sports, health habits, familial factors and subsequent mortality. We investigated all-cause mortality and health-related behaviour among former elite athletes and their brothers. The mortality of Finnish male former elite athletes, who had represented Finland between 1920 and 1965 (n=900) and their age-matched brothers (n=900), was followed from the time when athlete started an elite athlete career until 31 December 2015. The age-adjusted HRs were calculated by a paired Cox proportional hazards model. In 2001, surviving participants (n=199 athletes and n=199 age-matched brothers) reported their self-rated health (SRH), physical activity, alcohol consumption and smoking habits in the questionnaire. During the total follow-up period, 1296 deaths (72% of the cohort) occurred. The age-adjusted HRs for all-cause mortality in former athletes was 0.75 (95% CI 0.65 to 0.87, Ppower sports athletes, and 77.5, 73.7 and 72.2 years for their age-matched brothers, respectively. In 2001, compared with their brothers, former athletes smoked less (P<0.001), were more physically active (P<0.05) and rated their health more often as very good (P<0.05). Former elite athletes are more physically active, smoke less, have better self-rated health and live longer than their brothers. Genetic differences between athletes and brothers, aerobic training for endurance elite sports and a healthier lifestyle may all contribute to reduced mortality. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype

    OpenAIRE

    Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

    2014-01-01

    Background We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Methods Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. Results The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. T...

  14. Extreme right-handedness, older brothers, and sexual orientation in men.

    Science.gov (United States)

    Bogaert, Anthony F

    2007-01-01

    Two of the most consistent correlates of sexual orientation in men are handedness and fraternal birth order (i.e., number of older brothers). In the present study, the relationship among handedness, older brothers, and sexual orientation was studied in 4 samples of heterosexual and gay or bisexual men (N = 944). Unlike previous studies, which have only observed an increased rate of non-right-handedness in gay or bisexual men relative to heterosexual men, an elevated rate of extreme right-handedness was found in gay or bisexual men relative to heterosexual men. The results also demonstrated that older brothers moderate the relationship between handedness and sexual orientation. Specifically, older brothers increase the odds of being gay or bisexual in moderate right-handers only; in both non-right-handers and extreme right-handers, older brothers do not affect (or decrease) the odds of being gay or bisexual. The results have implications for an early neurodevelopmental origin to sexual orientation in men. (c) 2007 APA, all rights reserved.

  15. A Monument as a Text, or The Message of the Brothers Dostoevsky

    Directory of Open Access Journals (Sweden)

    Vladimir Zakharov

    2014-12-01

    Full Text Available The article considers the circumstances of the creation of a monument to the writer's mother Maria Fyodorovna Dostoevskaya. Mikhail Andreevich, father of the brothers Dostoevsky, asked Mikhail and Fyodor to compose the text for the monument. In March and April of 1837 the brothers worked out the idea and conception of the monument, wrote the text of the first and fourth epigraphs, chose evangelic verses and an epitaph of N.M. Karamzin. This was their first collective act of creative work embodied in stone. The monument is not only a symbol of love and sorrow for their mother’s death but also hope for her salvation and future resurrection. The brothers’ words and those chosen from the Gospel as well as the Karamzin’s ones have one more meaning. These convey a sense of beingness and an Easter idea of individual creative work. It is necessary to renew the tomb of Maria Fyodorovna Dostoevskaya and bring the monument back to Lazarevskoye cemetery in Moscow.

  16. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

    DEFF Research Database (Denmark)

    Bandak, M.; Jorgensen, N.; Juul, A.

    2017-01-01

    ) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39–50) vs. 46 (40–53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7–19). Serum levels...... was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular...... cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III...

  17. "Southern Pop Culture and the Literary Tradition in O Brother, Where Art Thou?"

    DEFF Research Database (Denmark)

    Bjerre, Thomas Ærvold

    2009-01-01

      This essay discusses the Coen brothers movie O Brother, Where Art Thou? (2000). Rather than reading the movie as a modern retelling of The Odyssey, as most critics have done, it is read within a context of Southern literature and history. The essay points out and discusses the many references...

  18. Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

    Directory of Open Access Journals (Sweden)

    Nadia Skauli

    2016-11-01

    Full Text Available Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3, characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val in two brothers with several of the typical features of MCAHS3, but in addition, pyramidal tract neurological signs. Notably, they are the first patients with MCAHS3 without skeletal, cardiac, or genitourinary anomalies. PIGT encodes a crucial subunit of the glycosylphosphatidylinositol (GPI transamidase complex, which catalyzes the attachment of proteins to GPI-anchors, attaching the proteins to the cell membrane. In vitro studies in cells from the two brothers showed reduced levels of GPI-anchors and GPI-anchored proteins on the cell surface, supporting the pathogenicity of the novel PIGT variant.

  19. The Role of Digital Literacy Practices on Refugee Resettlement: The Case of Three Karen Brothers

    Science.gov (United States)

    Gilhooly, Daniel; Lee, Eunbae

    2014-01-01

    This study explores the social and cultural uses of digital literacies by adolescent immigrants to cope with their new lives in the United States. This case study focuses on three adolescent ethnic Karen brothers. Two years of participant observations in their home and Karen community, accompanied by formal and informal interviews, served as the…

  20. 76 FR 1985 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2011-01-12

    ... Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes AGENCY: Federal Aviation Administration (FAA..., at an average labor rate of $85 per work hour. Required parts cost about $10 per product. Based on.... The average labor rate is $85 per work-hour. Based on these figures, we estimate the cost of the AD on...

  1. Inherited germline ATRX mutation in two brothers with ATR-X syndrome and osteosarcoma.

    Science.gov (United States)

    Ji, Jianling; Quindipan, Catherine; Parham, David; Shen, Lishuang; Ruble, David; Bootwalla, Moiz; Maglinte, Dennis T; Gai, Xiaowu; Saitta, Sulagna C; Biegel, Jaclyn A; Mascarenhas, Leo

    2017-05-01

    We report a family in which two brothers had an undiagnosed genetic disorder comprised of dysmorphic features, microcephaly, severe intellectual disability (non-verbal), mild anemia, and cryptorchidism. Both developed osteosarcoma. Trio exome sequencing (using blood samples from the younger brother and both parents) was performed and a nonsense NM_000489.4:c.7156C>T (p.Arg2386*) mutation in the ATRX gene was identified in the proband (hemizygous) and in the mother's peripheral blood DNA (heterozygous). The mother is healthy, does not exhibit any clinical manifestations of ATR-X syndrome and there was no family history of cancer. The same hemizygous pathogenic variant was confirmed in the affected older brother's skin tissue by subsequent Sanger sequencing. Chromosomal microarray studies of both brothers' osteosarcomas revealed complex copy number alterations consistent with the clinical diagnosis of osteosarcoma. Recently, somatic mutations in the ATRX gene have been observed as recurrent alterations in both osteosarcoma and brain tumors. However, it is unclear if there is any association between osteosarcoma and germline ATRX mutations, specifically in patients with constitutional ATR-X syndrome. This is the first report of osteosarcoma diagnosed in two males with ATR-X syndrome, suggesting a potential increased risk for cancer in patients with this disorder. © 2017 Wiley Periodicals, Inc.

  2. My Brother as "Problem": Neoliberal Governmentality and Interventions for Black Young Men and Boys

    Science.gov (United States)

    Dumas, Michael J.

    2016-01-01

    In this article, the author argues that the Obama Administration's My Brother's Keeper (MBK) initiative serves as an exemplar of neoliberal governmentality, in which Black young men and boys are constructed as essentially damaged, as problems in need of a technocratic public--private solution. More than simply an ideological imposition from above…

  3. When Your "Problem" Becomes Mine: Adult Female Siblings' Perspectives of Having a Brother with a Disability

    Science.gov (United States)

    Pompeo, Michelle N.

    2009-01-01

    This study is a retrospective look at adult female siblings' perspectives of their childhoods and present identities based on having a brother with a disability. This paper focuses on siblings' experiences within educational and public domains, and how such experiences have shaped their personalities and career choices. Qualitative findings were…

  4. A Thousand Lights [and] A Thousand Lights: Teacher and Parent Guide. Brothers Series.

    Science.gov (United States)

    Benton, Hope

    This book for children (ages 8 to 14) and the accompanying teacher/parent guide present the story of two brothers, one of whom has a severe hearing impairment, who climb up Mt. Fuji in Japan. Information on the disability is presented subtly and incidentally to encourage the reader to relate more personally and foster a deeper level of acceptance…

  5. Brothers and Sisters of Adults with Mental Retardation: Gendered Nature of the Sibling Relationship.

    Science.gov (United States)

    Orsmond, Gael I.; Seltzer, Marsha Mailick

    2000-01-01

    Differences and similarities between 245 brothers and sisters of adults with mental retardation in the sibling relationship were examined. Sisters scored higher in the caregiving, companionship, and positive affect aspects of the sibling relationship. Sibling involvement increased over time, but was dependent upon changes in maternal health.…

  6. Improving Emotion Regulation and Sibling Relationship Quality: The More Fun with Sisters and Brothers Program

    Science.gov (United States)

    Kennedy, Denise E.; Kramer, Laurie

    2008-01-01

    We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…

  7. Mentoring in Schools: An Impact Study of Big Brothers Big Sisters School-Based Mentoring

    Science.gov (United States)

    Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; McMaken, Jennifer

    2011-01-01

    This random assignment impact study of Big Brothers Big Sisters School-Based Mentoring involved 1,139 9- to 16-year-old students in 10 cities nationwide. Youth were randomly assigned to either a treatment group (receiving mentoring) or a control group (receiving no mentoring) and were followed for 1.5 school years. At the end of the first school…

  8. "Brothers and Sisters": A Novel Way to Teach Human Resources Management.

    Science.gov (United States)

    Bumpus, Minnette

    2000-01-01

    The novel "Brothers and Sisters" by Bebe Moore Campbell was used in a management course to explore human resource management issues, concepts, and theories. The course included prereading and postreading surveys, lecture, book review, and examination. Most of the students (92%) felt the novel was an appropriate way to meet course…

  9. Blood Brothers: Albert and Allen Hughes in the Belly of the Hollywood Beast.

    Science.gov (United States)

    Gates, Henry Louis, Jr.

    1994-01-01

    Recounts an interview with the Hughes brothers, who are twin black men who produced the film "Menace 2 Society," which is a film about urban delinquency and crime among black adolescents. Their comments include thoughts on racism, media stereotyping, being black in America, and their experiences with Hollywood. (GLR)

  10. Family Configuration and Achievement: Effects of Birth Order and Family Size in a Sample of Brothers.

    Science.gov (United States)

    Olneck, Michael R.; Bills, David B.

    1979-01-01

    Birth order effects in brothers were found to derive from difference in family size. Effects for family size were found even with socioeconomic background controlled. Nor were family size effects explained by parental ability. The importance of unmeasured preferences or economic resources that vary across families was suggested. (Author/RD)

  11. Testicular cancer in two brothers of a quadruplet: a case report and a review of literature.

    Science.gov (United States)

    Ulytė, Agnė; Ulys, Albertas; Sužiedėlis, Kęstutis; Patašius, Aušvydas; Smailytė, Giedrė

    2017-01-01

    Introduction. Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Case description. Both patients were diagnosed at 21 years of age and died within two years from the diagnosis despite treatment. The third symptomless brother did not have testicular pathology. We also review the risk factors associated with testicular cancer, and the proposed hypotheses how a multiple birth results in an increased risk. The most consistent risk factors for testicular cancer are cryptorchidism, prior history of testicular cancer, and a positive familial history. According to different studies, the risk of testicular cancer in twins is higher from 22% to 30%, compared to the general population. Conclusions. To our knowledge, we have presented the first case of testicular teratoblastoma in brothers of a quadruplet.

  12. A sterile sperm caste protects brother fertile sperm from female-mediated death in Drosophila pseudoobscura

    DEFF Research Database (Denmark)

    Holman, Luke; Snook, Rhonda R

    2008-01-01

    antispermicidal mechanisms have been definitively identified. One such adaptation may be the enigmatic infertile sperm morphs or "parasperm" produced by many species, which have been hypothesized to protect their fertile brother "eusperm" from spermicide [2, 3]. Here, we show that female Drosophila pseudoobscura...

  13. Exercise electrocardiogram testing in two brothers with different outcome – a case study exercise testing in master cyclists

    Directory of Open Access Journals (Sweden)

    Rüst CA

    2013-06-01

    Full Text Available Christoph Alexander Rüst,1 Beat Knechtle,1,2 Thomas Rosemann11Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, SwitzerlandAbstract: The cases of two brothers training and competing as master cyclists and both preparing for a cycling tour are presented. The older brother aged 66 years went first to the primary care physician and presented with an asymptomatic depression in the exercise stress test of the ST segment in V5 and V6 during recovery after complete exhaustion. Coronary angiography revealed a multi vessel coronary artery disease and he underwent bypass surgery. One year later, he successfully completed his planned cycling tour of ~600 km in seven stages and covering ~12,000 m of total ascent. The younger brother aged 59 years went a few months later to the primary care physician and also performed asymptomatic exercise stress testing without changes in the ST segments. Unfortunately, 2 months later he suffered a cardiac arrest during his cycling tour and survived following immediate successful cardiopulmonary resuscitation on the road by his cycling colleagues. Immediate invasive coronary arteriography showed a complete stenosis of the trunk of arteria coronaria sinistra (left coronary artery, a 40%–50% stenosis of ramus circumflexus, and a 20% stenosis of arteria coronaria dextra (right coronary artery. The left coronary artery was dilated and he continued cycling 2 months later. In both brothers, familial hypercholesterolemia was the main cardiovascular risk factor for the multi vessel coronary artery disease. A negative exercise electrocardiogram in siblings with an increased risk for coronary artery disease seemed not to exclude an advanced multi vessel coronary artery disease. In master athletes with asymptomatic exercise electrocardiogram but a positive family history, further examinations should be performed in order to detect

  14. Reluctant Romantics – On the fairy tale poetics of the Brothers Grimm and their relationship to German Romanticism

    Directory of Open Access Journals (Sweden)

    Isabel dos Santos

    2014-12-01

    Full Text Available The legacy of the Brothers Grimm continues to fascinate readers and researchers alike. The 200-year anniversary of the first publication of their fairy tales sparked a renewed interest in the life, work and times of the brothers. Fascinated by the past, by the political present and by the literary future of Romanticism, the Brothers Grimm stayed together in an unusual working union. They established what was to become German philology and published many invaluable works on language and history, myths and folk tales. This article will focus on the brothers’ place in German Romanticism through their contribution of fairy tales. The period was marked by political and philosophical thought that emphasised authentic experienced and the spiritual unity of art, science and philosophy. There was a strong call for national emancipation. Literature was required to embody this unity through an established national literature founded on German folk traditions. The Grimms seemed to have heeded that call. But a careful study reveals that their intentions were motivated less by the literary movement than by their own strong convictions which they upheld even at the cost of compromising the authenticity they claimed to uphold in their poetics. The many controversies regarding the origins, collection and editing of the fairy tales is inextricably linked to the brothers’ difficult relationship with the Romantic Movement. Two hundred years later, this article seeks to give an appraisal of the Brothers’ motivation for their poetics and of the research conducted thus far.

  15. Extreme intrafamilial variability of Saudi brothers with primary hyperoxaluria type 1

    Directory of Open Access Journals (Sweden)

    Alfadhel M

    2012-08-01

    Full Text Available Majid Alfadhel,1 Khalid A Alhasan,2 Mohammed Alotaibi,3 Khalid Al Fakeeh41Division of Genetics, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 2Division of Nephrology Department of Pediatrics, King Saud University King Khalid University Hospital, Riyadh, Saudi Arabia; 3Department of Radiology, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 4Division of Nephrology, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi ArabiaBackground: Primary hyperoxaluria type 1 (PH1 is characterized by progressive renal insufficiency culminating in end-stage renal disease, and a wide range of clinical features related to systemic oxalosis in different organs. It is caused by autosomal recessive deficiency of alanine:glyoxylate aminotransferase due to a defect in AGXT gene.Case report: Two brothers (one 6 months old; the other 2 years old presented with acute renal failure and urinary tract infection respectively. PH1 was confirmed by high urinary oxalate level, demonstration of oxalate crystals in bone biopsy, and pathogenic homozygous known AGXT gene mutation. Despite the same genetic background, same sex, and shared environment, the outcome of the two siblings differs widely. While one of them died earlier with end-stage renal disease and multiorgan failure caused by systemic oxalosis, the older brother is pyridoxine responsive with normal development and renal function.Conclusion: Clinicians should be aware of extreme intrafamilial variability of PH1 and international registries are needed to characterize the genotype-phenotype correlation in such disorder.Keywords: primary hyperoxaluria, oxalosis, PH1, intrafamilial variability

  16. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers.

    Science.gov (United States)

    Bandak, M; Jørgensen, N; Juul, A; Lauritsen, J; Kier, M G G; Mortensen, M S; Oturai, P S; Mortensen, J; Hojman, P; Helge, J W; Daugaard, G

    2017-07-01

    Testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to healthy controls. However, because of the fetal etiology of testicular cancer, familial unrelated healthy men might not be an optimal control group. The objective of this study was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39-50) vs. 46 (40-53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7-19). Serum levels of luteinizing hormone and follicle-stimulating hormone were elevated (p ≤ 0.001), while total testosterone, free testosterone, inhibin B and anti-Müllerian hormone were lower (p ≤ 0.001) in testicular cancer survivors than in their biological brothers. The prevalence of metabolic syndrome was similar and apart from HDL-cholesterol, which was lower in testicular cancer survivors (p = 0.01); there were no differences in the individual components of the metabolic syndrome between testicular cancer survivors and their brothers. In conclusion, gonadal function was impaired in testicular cancer survivors, while we did not detect any difference in the prevalence of metabolic syndrome between testicular cancer survivors and their biological brothers. © 2017 American

  17. Brothers and reduction of the birth weight of later-born siblings

    DEFF Research Database (Denmark)

    Nielsen, Henriette Svarre; Mortensen, Laust; Nygaard, Ulrikka

    2008-01-01

    It has been speculated whether maternal immune responses against male-specific minor histocompatibility (H-Y) antigens affect pregnancies negatively. This study explores, on a population level, whether previous births of boys compared with girls are associated with a decrease in birth weight...... of later-born siblings. The population was identified in the Danish Birth Registry and consisted of all Danish women who gave birth to their first-born singleton from 1980 to 1998. The women were followed until 2004, and their subsequent births were recorded. A total of 545,839 second- to fourth......-born children were identified. The authors used linear regression to analyze the association between sex of preceding children and birth weight of subsequent siblings. Brothers compared with sisters reduced the birth weight of later-born siblings. One or two brothers, respectively, reduced the mean birth weight...

  18. Catholic nursing sisters and brothers and racial justice in mid-20th-century America.

    Science.gov (United States)

    Wall, Barbra Mann

    2009-01-01

    This historical article considers nursing's work for social justice in the 1960s civil rights movement through the lens of religious sisters and brothers who advocated for racial equality. The article examines Catholic nurses' work with African Americans in the mid-20th century that took place amid the prevailing social conditions of poverty and racial disempowerment, conditions that were linked to serious health consequences. Historical methodology is used within the framework of "bearing witness," a term often used in relation to the civil rights movement and one the sisters themselves employed. Two situations involving nurses in the mid-20th century are examined: the civil rights movement in Selma, Alabama, and the actions for racial justice in Chicago, Illinois. The thoughts and actions of Catholic sister and brother nurses in the mid-20th century are chronicled, including those few sister nurses who stepped outside their ordinary roles in an attempt to change an unjust system entirely.

  19. ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing

    OpenAIRE

    Moncini, S.; Bedeschi, M.F.; Castronovo, P.; Crippa, M.; Calvello, M.; Garghentino, R.R.; Scuvera, G.; Finelli, P.; Venturin, M.

    2013-01-01

    In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allow...

  20. Learning to Fly: The Wright Brothers' Adventure. A Guide for Educators and Students with Activities in Aeronautics

    Science.gov (United States)

    Storm, R.; Benson, T.; Galica, C.; McCredie, P.

    2003-01-01

    This guide was produced by the NASA Glenn Research Center Office of Educational Programs in Cleveland, OH, and the NASA Aerospace Educational Coordinating Committee. It includes activity modules for students, including the history of the Wright Brothers and their family in Dayton, Ohio and flight experimentation in Kitty Hawk, North Carolina. Student activities such as building models of the Wright Brothers glider and writing press releases of the initial flight are included.

  1. Magnetic resonance in Pelizaeus Merzbacher disease: findings in three brothers presenting the connatal variant

    International Nuclear Information System (INIS)

    Saez, J.; Perez, F.; Fuster, M.J.; Marti, L.

    1997-01-01

    Pelizaeus Merzbacher disease is a rare hereditary disorder of the white matter that is characterized by nystagmic eye movements, head shaking and severe psychomotor retardation. We report the MR findings in three brothers presenting the connatal variant of the disease, which is characterized by a diffuse increase in signal intensity on T2-weighted sequences, involving the white matter of the CNS. (Author) 10 refs

  2. Biological versus nonbiological older brothers and men’s sexual orientation

    OpenAIRE

    Bogaert, Anthony F.

    2006-01-01

    The most consistent biodemographic correlate of sexual orientation in men is the number of older brothers (fraternal birth order). The mechanism underlying this effect remains unknown. In this article, I provide a direct test pitting prenatal against postnatal (e.g., social/rearing) mechanisms. Four samples of homosexual and heterosexual men (total n = 944), including one sample of men raised in nonbiological and blended families (e.g., raised with half- or step-siblings or as adoptees) were ...

  3. On Brothers and Sisters: South Asian and Japanese Idea Systems and their Consequences

    OpenAIRE

    Lyon, Stephen M.

    2017-01-01

    The role expectations of cross siblings varies across culture. Such expectations, while not rigidly prescribing actual behaviors nevertheless influences relations between brothers and sisters in observable ways. In South Asia, a cultural rhetoric of sororal sacrifice and support coupled with fraternal protection are commonplace. While such noble sibling roles are regularly transgressed they remain powerful idioms of the relationship and transgressions require appropriate cultural justificatio...

  4. A new syndrome: multiple congenital abnormalities and mental retardation in two brothers.

    Science.gov (United States)

    Dundar, M; Ozdemir, S Y; Fryns, J P

    2012-01-01

    In this report we present two brothers with abnormal neurological development, hypotonia, short stature, pylorus stenosis, pectus excavatum, brachycephaly due to craniosynostosis, frontal bossing, depressed nasal bridge, high arched-wide palate, downslant palpebral fissures, low-set, large ears, thin upper lip and bilateral cryptorchidism. The brothers were born to a couple of second cousins and were the third and fourth pregnancies of the mother. The father, the mother and the eldest sibling were phenotypically and chromosomally normal. The clinical findings of the brothers were found to be similar. These clinical findings were compared with syndromes showing some of the symptoms, namely Apert, FG, Floating-Harbor, Shprintzen-Goldberg and Rett Syndromes. However, when the findings were detailed, we observed that they did not match completely any of the syndromes in a discernable way. The MECP2 gene mutation was analysed because of mental retardation, poor neurological evolution and large ears, but no mutation was found. So these cases are presented as a new syndrome with apparent autosomal recessive inheritance.

  5. Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

    Directory of Open Access Journals (Sweden)

    Verhoeven WMA

    2012-04-01

    Full Text Available Willem MA Verhoeven1,2, Jos IM Egger1,3,4, Marjolein H Willemsen5, Gert JM de Leijer6, Tjitske Kleefstra51Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray, 2Erasmus University Medical Centre, Department of Psychiatry, Rotterdam, 3Donders Centre for Cognition, Radboud University Nijmegen, Nijmegen, 4Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, 5Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, 6Dichterbij, Institutes for Intellectual Disabilities, Gennep, The NetherlandsAbstract: The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances, communication deficits, and motor perseverations. Data on psychological dysfunctions are so far not available. Previous studies have suggested that the loss of one copy of the gene SH3 and multiple ankyrin repeat domains 3 (SHANK3 is related to the neurobehavioral phenotype. Additional genes proximal to SHANK3 are also likely to play a role in the phenotype of patients with larger deletions. The present paper describes two adult brothers with an identical 2.15 Mb 22qter (22q13.32q13.33 deletion, of whom the youngest was referred for evaluation of recurrent mood changes. In both patients, magnetic resonance imaging of the brain showed hypoplasia of the vermis cerebelli. Extensive clinical examinations led to a final diagnosis of atypical bipolar disorder, of which symptoms fully remitted during treatment with a mood stabilizer. In the older brother, a similar psychopathological picture appeared to be present, although less severe and with a later onset. It is concluded that the behavioral phenotype of the 22q13.3 deletion syndrome comprises absent or delayed speech and perseverations

  6. Power in Play: A Foucauldian Reading of A.O. Soyinka’s The Trials of Brother Jero

    Directory of Open Access Journals (Sweden)

    Mahboobeh Davoodifar

    2015-12-01

    Full Text Available This work utilizes Foucault’s articulations on the power strategies of our contemporary society. To him the subject’s constitution is never a purely passive effect of power on the subject but requires the subject’s own activity. This necessitates the existence of a dynamic, mutually affecting relationship, implying that one can be both dominated and dominate at different times and in different contexts. This article aims to analyze the Nigerian Noble Laureate, Wole Soyinka’s play The Trials of Brother Jero, a prophetical play that criticizes the ills of society through its satirical depiction, in the light of Foucault’s conceptualizations on power. To do this, the article first clarifies Foucault’s mature understanding of the operation of power and then attempts to provide an in-depth analysis of the structure of the power regime and its relations in the play, tactics of domination, and more importantly, the characters’ relations to the existing system of power. The study of the language and the dialogue of the main characters, Brother Jero, Amope, Chume and a Member of Federation House not only exposes the sources of operating power relations, but it also highlights the characters’ desire for power and the way it flows and slips from one character to another. The findings of the paper reveals that power is not concentrated on merely one character or institution within the play, rather, it circulates, and through the active resistance of the dominated characters, it constantly engenders new meanings within the structure of the play. In The Trials of Brother Jero, different characters have the desire to use power against each other and the resistance of each of them indicates that power is neither possessive nor repressive. Keywords: Michel Foucault, Power, Pastoral Power, Resistance, Wole Soyinka

  7. Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype.

    Science.gov (United States)

    Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

    2014-09-19

    We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. To the best of our knowledge, no similar phenotype has been reported previously. No abnormalities were detected by G-banding chromosome analysis or array comparative genomic hybridization. However, exome sequencing revealed novel mutations in the ATP-binding cassette, sub-family D member 1 (ABCD1) and Dachshund homolog 2 (DACH2) genes in both brothers. The ABCD1 mutation was a missense mutation c.1126G > C in exon 3 leading to a p.E376Q substitution. The DACH2 mutation was also a missense mutation c.1069A > T in exon 6, leading to a p.S357C substitution. The mother was an asymptomatic heterozygous carrier. Plasma levels of very-long-chain fatty acids were increased in both brothers, suggesting a diagnosis of adrenoleukodystrophy (ALD); however, their phenotype was not compatible with any reported forms of ALD. DACH2 plays an important role in the regulation of brain and limb development, suggesting that this mutation may be involved in the phenotype of the two brothers. The distinct phenotype demonstrated by these two brothers might represent a new form of ALD or a new syndrome. The combination of mutations in ABCD1 and DACH2 provides a plausible mechanism for this phenotype.

  8. Qualitative comparative analysis of Grimm brothers' and Manica Koman's fairy tales, based on the structuralist literary theory of Vladimir J. Propp

    OpenAIRE

    Ložar, Ana

    2012-01-01

    The present BA thesis, titled A Qualitative Comparative Analysis of Grimm Brothers' and Manica Koman's Fairy Tales, Based on the Structuralist Literary Theory of Vladimir J. Propp, consists of two parts. The first one presents the biography and work of the Grimm brothers, and the biography and work of Manica Koman, a Slovene folktale writer. Biography and work facts about the former were mainly found in Hermann Gerstner's detailed biography of the Brothers Grimm, Die Brűder Grimm: Ei...

  9. Lipid myopathy associated with renal tubular acidosis and spastic diplegia in two brothers.

    Science.gov (United States)

    Tung, Y C; Tsau, Y K; Chu, L W; Young, C; Shen, Y Z

    2001-07-01

    Lipid myopathy is a group of disorders involving mitochondrial fatty acid oxidation. We describe two brothers, 3 years 8 months old and 2 years 9 months old, respectively, with progressive spastic diplegia, developmental delay, failure to thrive, and chronic metabolic acidosis who had lipid myopathy and renal tubular acidosis. Brain magnetic resonance imaging revealed demyelinating changes in the periventricular white matter, which was compatible with spastic diplegia. These symptoms may be related to errors in fatty acid metabolism. Cerebral palsy had been misdiagnosed in both of these patients at another hospital. Therefore, for patients with late-onset and progressive spastic diplegia, detailed investigations for underlying diseases are warranted.

  10. Germline activating MTOR mutation arising through gonadal mosaicism in two brothers with megalencephaly and neurodevelopmental abnormalities.

    Science.gov (United States)

    Mroske, Cameron; Rasmussen, Kristen; Shinde, Deepali N; Huether, Robert; Powis, Zoe; Lu, Hsiao-Mei; Baxter, Ruth M; McPherson, Elizabeth; Tang, Sha

    2015-11-05

    In humans, Mammalian Target of Rapamycin (MTOR) encodes a 300 kDa serine/ threonine protein kinase that is ubiquitously expressed, particularly at high levels in brain. MTOR functions as an integrator of multiple cellular processes, and in so doing either directly or indirectly regulates the phosphorylation of at least 800 proteins. While somatic MTOR mutations have been recognized in tumors for many years, and more recently in hemimegalencephaly, germline MTOR mutations have rarely been described. We report the successful application of family-trio Diagnostic Exome Sequencing (DES) to identify the underlying molecular etiology in two brothers with multiple neurological and developmental lesions, and for whom previous testing was non-diagnostic. The affected brothers, who were 6 and 23 years of age at the time of DES, presented symptoms including but not limited to mild Autism Spectrum Disorder (ASD), megalencephaly, gross motor skill delay, cryptorchidism and bilateral iris coloboma. Importantly, we determined that each affected brother harbored the MTOR missense alteration p.E1799K (c.5395G>A). This exact variant has been previously identified in multiple independent human somatic cancer samples and has been shown to result in increased MTOR activation. Further, recent independent reports describe two unrelated families in whom p.E1799K co-segregated with megalencephaly and intellectual disability (ID); in both cases, p.E1799K was shown to have originated due to germline mosaicism. In the case of the family reported herein, the absence of p.E1799K in genomic DNA extracted from the blood of either parent suggests that this alteration most likely arose due to gonadal mosaicism. Further, the p.E1799K variant exerts its effect by a gain-of-function (GOF), autosomal dominant mechanism. Herein, we describe the use of DES to uncover an activating MTOR missense alteration of gonadal mosaic origin that is likely to be the causative mutation in two brothers who present

  11. The first mutation in CNGA2 in two brothers with anosmia

    DEFF Research Database (Denmark)

    Karstensen, H G; Mang, Y; Fark, T

    2015-01-01

    that the cyclic nucleotide-gated channel subunit CNGA2, expressed in the olfactory epithelium has a crucial role in olfactory signal transduction. We have identified a novel X-linked stop mutation in CNGA2 (c.634C>T, p.R212*) in two brothers with ICA using exome sequencing. No additional mutations in CNGA2 were...... identified in a cohort of 31 non-related ICA individuals. Magnetic resonance brain imaging revealed diminished olfactory bulbs and flattened olfactory sulci. This is the first report of a mutation in the cyclic nucleotide-gated gene CNGA2 and supports the critical role of this gene in human olfaction....

  12. Brothers in arms? Portuguese and Brazilian journalistic worlds compared

    Directory of Open Access Journals (Sweden)

    Rui Alexandre Novais

    2013-06-01

    Full Text Available This study aims to gauge if there is a ‘de-territorialized’ Portuguese speaking journalistic community or whether diverse professional self-perceptions prevail amongst Portuguese and Brazilian counterparts. Based upon an extensive and manifold comparative analysis of 200 questionnaires – comprising the ‘journalism cultures’, their trust on social institutions’ and the ‘perceived influences on news work’ - it contrasts the cultural proximity of both countries, alongside a degree of globalization, with their rather dissimilar respective political and media contexts. It concludes that notwithstanding the expected psychological proximity and some signs of convergence between the two countries, the comparative evidence displays considerable differences which are the result of their respective institutional, social and cultural embedding. Thus, those partially different professional cultures prevent the existence of a translocal Portuguese speaking journalistic culture and corroborate the importance the contextual conditions

  13. BROTHERS IN ARMS? PORTUGUESE AND BRAZILIAN JOURNALISTIC WORLDS COMPARED

    Directory of Open Access Journals (Sweden)

    Rui Alexandre Novais

    2013-06-01

    Full Text Available This study aims to gauge if there is a ‘de-territorialized’ Portuguese speaking journalistic community or whether diverse professional self-perceptions prevail amongst Portuguese and Brazilian counterparts. Based upon an extensive and manifold comparative analysis of 200 questionnaires – comprising the ‘journalism cultures’, their trust on social institutions’ and the ‘perceived influences on news work’ - it contrasts the cultural proximity of both countries, alongside a degree of globalization, with their rather dissimilar respective political and media contexts. It concludes that notwithstanding the expected psychological proximity and some signs of convergence between the two countries, the comparative evidence displays considerable differences which are the result of their respective institutional, social and cultural embedding. Thus, those partially different professional cultures prevent the existence of a translocal Portuguese speaking journalistic culture and corroborate the importance the contextual conditions

  14. Bernoulli Brothers

    Indian Academy of Sciences (India)

    In the long, glorious history of mathematics, we come across ... family flourished in business, but afterwards, its descendants .... teaching calculus to contemporary renowned mathematicians including Guillaume FrancoiseAntoiRe de.

  15. Changes in Siblings Over Time After the Death of a Brother or Sister From Cancer.

    Science.gov (United States)

    Akard, Terrah Foster; Skeens, Micah A; Fortney, Christine A; Dietrich, Mary S; Gilmer, Mary Jo; Vannatta, Kathryn; Barrera, Maru; Davies, Betty; Wray, Sarah; Gerhardt, Cynthia A

    2018-02-27

    Limited research has examined the impact of a child's death from cancer on siblings. Even less is known about how these siblings change over time. This study compared changes in siblings 1 (T1) and 2 (T2) years after the death of a brother or sister from cancer based on bereaved parent and sibling interviews. Participants across 3 institutions represented 27 families and included bereaved mothers (n = 21), fathers (n = 15), and siblings (n = 26) ranging from 8 to 17 years old. Participants completed semistructured interviews. Content analysis identified emerging themes and included frequency counts of participant responses. McNemar tests examined differences in the frequency of responses between T1 and T2 data. Participants reported similar types of changes in bereaved siblings at both time points, including changes in sibling relationships, life perspectives, their personal lives, and school performance. A new theme of "openness" emerged at T2. Frequencies of responses differed according to mother, father, or sibling informant. Overall, participants less frequently reported changes at T2 versus T1. Compared with findings in the first year, participants reported greater sibling maturity at follow-up. Overall changes in bereaved siblings continued over 2 years with less frequency over time, with the exception of increases in maturity and openness. Providers can educate parents regarding the impact of death of a brother or sister over time. Nurses can foster open communication in surviving grieving siblings and parents as potential protective factors in families going through their grief.

  16. A Song in the Dark. Francis of Assisi’s Canticle of Brother Sun

    Directory of Open Access Journals (Sweden)

    Speelman Willem Marie

    2016-10-01

    Full Text Available The Canticle of the Creatures or Canticle of Brother Sun is based on a particular way of perceiving reality. Francis, who had turned away from ‘the world’, discovered a different way of looking at it. This is a divine way of perceiving, in which the senses do not grasp reality, but accept it as it communicates itself. This way of perceiving is only possible if one does not attempt to master the environment, but allows one’s senses to be weak. It is significant, therefore, that this song of praise was born at a moment of the utmost despair and weakness. The song’s content is in line with this weak perception: it is not about Francis who praises God and (or for His creatures, but rather it is a testimony that the creatures-the elements-are already praising God, and a prayer that He should let Himself be praised by the creatures. Also in line with this weak perception is the fact that the creatures are praised just as they communicate themselves to Francis: as bodies. The theology of this song is that the creatures through their bodies resonate (strengthen, and colour the blessings that come from God, thereby making His blessing present here on earth. Francis’ role is to give a voice and a language to the heavenly praises as they resound in his environment. The transformative power of this song is that we, whether consciously or not, do the same thing when we participate in this song.

  17. Expression of the central growth regulator BIG BROTHER is regulated by multiple cis-elements

    Directory of Open Access Journals (Sweden)

    Breuninger Holger

    2012-03-01

    Full Text Available Abstract Background Much of the organismal variation we observe in nature is due to differences in organ size. The observation that even closely related species can show large, stably inherited differences in organ size indicates a strong genetic component to the control of organ size. Despite recent progress in identifying factors controlling organ growth in plants, our overall understanding of this process remains limited, partly because the individual factors have not yet been connected into larger regulatory pathways or networks. To begin addressing this aim, we have studied the upstream regulation of expression of BIG BROTHER (BB, a central growth-control gene in Arabidopsis thaliana that prevents overgrowth of organs. Final organ size and BB expression levels are tightly correlated, implying the need for precise control of its expression. BB expression mirrors proliferative activity, yet the gene functions to limit proliferation, suggesting that it acts in an incoherent feedforward loop downstream of growth activators to prevent over-proliferation. Results To investigate the upstream regulation of BB we combined a promoter deletion analysis with a phylogenetic footprinting approach. We were able to narrow down important, highly conserved, cis-regulatory elements within the BB promoter. Promoter sequences of other Brassicaceae species were able to partially complement the A. thaliana bb-1 mutant, suggesting that at least within the Brassicaceae family the regulatory pathways are conserved. Conclusions This work underlines the complexity involved in precise quantitative control of gene expression and lays the foundation for identifying important upstream regulators that determine BB expression levels and thus final organ size.

  18. Persistence of Müllerian derivatives and intestinal lymphangiectasis in two newborn brothers: confirmation of the Urioste syndrome

    NARCIS (Netherlands)

    Bellini, C.; Bonioli, E.; Josso, N.; Belville, C.; Mazzella, M.; Costabel, S.; Sementa, A. R.; Marino, C. E.; Tomà, P.; Hennekam, R. C.; Serra, G.

    2001-01-01

    We describe two newborn brothers with a pattern of malformation characterized by the persistence of Müllerian duct derivatives, intestinal lymphangiectasia, hypertrophied alveolar ridges, and early death. Postmortem examination showed the presence of a rudimentary uterus, fallopian tubes, the upper

  19. 20 CFR 222.40 - When determinations of relationship are made for parent, grandchild, brother or sister.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When determinations of relationship are made... RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent..., brother or sister. (a) Parent. The claimant's relationship as a parent of the employee is determined when...

  20. ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing.

    Science.gov (United States)

    Moncini, S; Bedeschi, M F; Castronovo, P; Crippa, M; Calvello, M; Garghentino, R R; Scuvera, G; Finelli, P; Venturin, M

    2013-12-01

    In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allowed the identification of the ATRX c.109C>T (p.R37X) mutation in both the affected brothers. Sanger sequencing confirmed the presence of the mutation in the brothers and showed that the mother is a healthy carrier. Mutations in the ATRX gene cause the X-linked alpha thalassemia/mental retardation (ATR-X) syndrome (MIM #301040), a severe clinical condition usually associated with profound ID, facial dysmorphism and alpha thalassemia. However, the syndrome is clinically heterogeneous and some mutations, including the c.109C>T, are associated with a broad phenotypic spectrum, with patients displaying a less severe phenotype with only mild-moderate ID. In the case presented here, exome sequencing provided an effective strategy to achieve the molecular diagnosis of ATR-X syndrome, which otherwise would have been difficult to consider due to the mild non-specific phenotype and the absence of a family history with typical severe cases.

  1. Gabriel García Márquez's «Eréndira» and the Brothers Grimm

    Directory of Open Access Journals (Sweden)

    Joel Hancock

    1978-08-01

    Full Text Available García Márquez's long story «La increíble y triste historia de la Cándida Eréndira y de su abuela desalmada» is studied in the light of the structures and themes of the fairy tale, particularly of the type collected by the Grimm brothers. Dimensions of special interest are the organizational framework of the narrative, the portrayal of characters, and certain motifs, all of which are strongly reminiscent of Grimm's Fairy Tales . These elements are examined as representative of those morphologies which Vladimir Propp delineates for the genre of the fairy tale in his Morphology of the Folktale .

  2. [1896: How nascent radiotherapy gathered Roentgen, Pasteur and the Lumière brothers].

    Science.gov (United States)

    Foray, N

    2016-12-01

    On the 4th July, 1896, in his medical office of Les Échelles (Savoie, France), Victor Despeignes performed the very first radiotherapy against cancer, documented by indisputable proofs. However, the intellectual and practical approach that leads to this first radiotherapy may appear unexpected to date. Indeed, it is likely that the treatment that Despeignes applied to his neighbour, who did not suffer from stomach cancer, was born with the indirect support of the Lumière brothers, on the basis of a biological theory (the parasitory theory of cancer) that is irrelevant today, with an experimental protocol based on experiments performed on tuberculosis et in a bifractionated model linked by the constraints of a district medical doctor. Copyright © 2016 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  3. [The brothers of Jumiege--the peripheral nervous system in early French mythology].

    Science.gov (United States)

    Brean, Are

    2002-03-20

    This article reviews the process of discovery of the nervous system from Pythagoras (570-500 BC) to Galen (130-201 AD). After Galen, no anatomical studies were performed before the renaissance. According to a legend, probably produced for political reasons, two brothers, sons of the French king Clovis II, revolted against their father and were sentenced to loose their physical powers by having the nerves of their arms and legs cut. They were then set adrift on the river Seine, stranding at the Jumiège monastery. The earliest written version of this legend stems from the fourteenth century; it was probably a part of the local French mythology. This indicates that the existence of the peripheral nervous system, and therefore also in part the knowledge contained in the early anatomical works, quite early may have been more or less known outside academic circles.

  4. Brothers with hypospadias, vertebral segmentation defects, and intellectual disability: new syndrome?

    Science.gov (United States)

    Phadke, Shubha R; Ranganath, Prajnya; Boggula, Vijay Raju; Gupta, Divya; Phadke, Rajendra V; Sloman, Melissa; Turnpenny, Peter D

    2012-12-01

    We report on two brothers (born to nonconsanguineous parents) with short stature, hypospadias, scoliosis, vertebral segmentation defects of "spondylocostal dysostosis" type, and intellectual disability. Results of cytogenetic and molecular genetic tests performed, including routine karyotype, MLPA (multiplex ligation-dependent probe amplification) for common microdeletions and subtelomeric copy number variants, microarray-CGH analysis, and sequencing of four Notch signaling pathway genes (DLL3, MESP2, LFNG, and HES7), were all normal. We present a comparison of the condition in the two boys with known syndromes and suggest that they may represent a hitherto unreported syndrome, most likely following autosomal recessive inheritance, though X-linked inheritance is not excluded. Copyright © 2012 Wiley Periodicals, Inc.

  5. Sustained virologic response following HCV eradication in two brothers with X-linked agammaglobulinaemia.

    LENUS (Irish Health Repository)

    Houlihan, Diarmaid D

    2009-08-21

    X-linked agammaglobulinaemia (XLA) is a humoral immunodeficiency syndrome characterized from childhood by the absence of circulating B lymphocytes, absent or reduced levels of serum immunoglobulin and recurrent bacterial infections. For many affected patients, regular treatment with immunoglobulin is life saving. Hepatitis C viral (HCV) infection acquired through contaminated blood products is widely described in this patient cohort. The natural history of HCV infection in patients with XLA tends to follow a more rapid and aggressive course compared to immunocompetent individuals. Furthermore, standard anti-viral therapy appears to be less efficacious in this patient cohort. Here we report the cases of two brothers with XLA who contracted HCV through contaminated blood products. They were treated with a six month course of Interferon alpha-2b and Ribavirin. We report a sustained virologic response five years after completing treatment.

  6. Constraints on the source of Cu in a submarine magmatic-hydrothermal system, Brothers volcano, Kermadec island arc

    Science.gov (United States)

    Keith, Manuel; Haase, Karsten M.; Klemd, Reiner; Smith, Daniel J.; Schwarz-Schampera, Ulrich; Bach, Wolfgang

    2018-05-01

    Most magmatic-hydrothermal Cu deposits are genetically linked to arc magmas. However, most continental or oceanic arc magmas are barren, and hence new methods have to be developed to distinguish between barren and mineralised arc systems. Source composition, melting conditions, the timing of S saturation and an initial chalcophile element-enrichment represent important parameters that control the potential of a subduction setting to host an economically valuable deposit. Brothers volcano in the Kermadec island arc is one of the best-studied examples of arc-related submarine magmatic-hydrothermal activity. This study, for the first time, compares the chemical and mineralogical composition of the Brothers seafloor massive sulphides and the associated dacitic to rhyolitic lavas that host the hydrothermal system. Incompatible trace element ratios, such as La/Sm and Ce/Pb, indicate that the basaltic melts from L'Esperance volcano may represent a parental analogue to the more evolved Brothers lavas. Copper-rich magmatic sulphides (Cu > 2 wt%) identified in fresh volcanic glass and phenocryst phases, such as clinopyroxene, plagioclase and Fe-Ti oxide suggest that the surrounding lavas that host the Brothers hydrothermal system represent a potential Cu source for the sulphide ores at the seafloor. Thermodynamic calculations reveal that the Brothers melts reached volatile saturation during their evolution. Melt inclusion data and the occurrence of sulphides along vesicle margins indicate that an exsolving volatile phase extracted Cu from the silicate melt and probably contributed it to the overlying hydrothermal system. Hence, the formation of the Cu-rich seafloor massive sulphides (up to 35.6 wt%) is probably due to the contribution of Cu from a bimodal source including wall rock leaching and magmatic degassing, in a mineralisation style that is hybrid between Cyprus-type volcanic-hosted massive sulphide and subaerial epithermal-porphyry deposits.

  7. My elder brother Fr Prof.Benignus Józef Wanat OCD. Personal family reminiscences

    Directory of Open Access Journals (Sweden)

    Edward Wanat

    2016-12-01

    Full Text Available Father Józef Benignus Wanat OCD was born in Frydrychowice, near Wadowice, into a large and impoverished farming family. He had seven brothers and one sister and was the third son of Franciszek and Maria Wanat. His hard working family was one of character displaying religious devotion, and demonstrating generosity to others in times of need. During the Nazi occupation, his parents took into their two-roomed house, a family of eight who were deprived of their own home in brutal circumstances. Out of necessity, and due to lack of space, the three oldest sons slept in the stable under the roof on a makeshift bed. After graduating from High School, and in answer to his calling, Benignus entered a novitiate in the Discalced Carmelites’ Monastery in Czerna. He completed his philosophy studies in Poznan and his theological studies at the Major Seminary of Discalced Carmelite Fathers in Kraków, where he was ordained a priest. In Krakow, at the Jagiellonian University’s Faculty of History and Philosophy, Fr. Benignus pursued extramural studies in the field of archives. He graduated from the Pontifical Academy of Theology in Kraków in the History of Art and having successfully defended his doctoral dissertation, he earned the the title of professor doctor. He was a member of the faculty of art in this university and he lectured on the History of Art of the Church with emphasis on European art. He was the founder of the Archives of the Discalced Carmelites in Czerna. He wrote prolifically on the History of Art of the Discalced Carmelite Order and the Discalced Carmelite Nuns researching and visiting many and various sites for his articles. This led to his magnumopus, a monograph on the Discalced Carmelite Order in Poland. He was elected several times as Provincial Superior of the Discalced Carmelites Province in Poland and he was appointed the first Provincial Superior of the Province of Kraków which included being the Prior of several monasteries

  8. [Undifferentiated soft tissue tumor with rhabdoid phenotype (extra-renal rhabdoid tumor). Report of a congenital case associated with medulloblastoma in a brother].

    Science.gov (United States)

    Costes, V; Medioni, D; Durand, L; Sarran, N; Marguerite, G; Baldet, P

    1997-03-01

    We report a case of congenital cervical rhabdoid tumor with association of a medulloblastoma in a brother. The immunohistochemical features of this tumor are compatible with a neuroectodermal differentiation (MIC 2+, Leu 7+). Extrarenal rhabdoid tumors share a common morphology but do not represent a single entity with only one histogenesis. Most of them are now considered to be of neuroectodermal origin. In our case, the association with a medulloblastoma in a brother seems to confirm this concept.

  9. Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

    International Nuclear Information System (INIS)

    Oliveira, G.; Boechat, M.I.; Fereira, M.A.

    1983-01-01

    A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process. (orig.)

  10. Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, G.; Boechat, M.I.; Fereira, M.A.

    1983-07-01

    A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

  11. Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

    OpenAIRE

    Skauli, Nadia; Wallace, Sean; Chiang, Samuel C. C.; Bar?y, Tuva; Holmgren, Asbj?rn; Stray-Pedersen, Asbj?rg; Bryceson, Yenan T.; Str?mme, Petter; Frengen, Eirik; Misceo, Doriana

    2016-01-01

    Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3), characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val) in two brothers w...

  12. HASIL RANCANG BANGUN SISTEM ERP DENGAN SDLC MODEL WATERFALL: STUDI KASUS SISTEM INVENTORI PT PAN BROTHERS, TBK.

    OpenAIRE

    Harijanto Pangestu; Hendra Alianto; Santo F. Wijaya

    2012-01-01

    Competition in the business world effects the use of information technology. To achieve competitive advantage in the global competition, PT Pan Brothers, Tbk. should establish an integrated information system based on ERP (Enterprise Resource Planning). With the ERP system, information will be accurate and up-todate to support strategic decision making. It takes conscientious planning in building the ERP system. Management information systems development projects have a very important role. O...

  13. Cancer risk in fathers and brothers of testicular cancer patients in Denmark. A population-based study.

    Science.gov (United States)

    Westergaard, T; Olsen, J H; Frisch, M; Kroman, N; Nielsen, J W; Melbye, M

    1996-05-29

    There are several reports of familial testicular cancer in the literature but few systematic attempts have been made to estimate the risk of testicular cancer in first-degree relatives of patients with this neoplasm, and the risk remains to be fully assessed in population-based studies. By means of data from the Danish Cancer Registry, we identified all testicular cancer patients (index cases) born and diagnosed during 1950-1993 in Denmark. Their fathers were identified from national registries, as were the brothers of a subcohort of these patients. Familial cancer occurrence was determined through linkage with the cancer registry and compared with the cancer incidence in the general male population in Denmark. The ratio of observed to expected cancers generated the measure used for the relative risk. Fathers of 2,113 index cases with testicular cancer experienced an almost 2-fold risk of developing testicular cancer themselves (RR = 1.96; 95% CI: 1.01-3.43). Overall, the fathers had a decreased relative cancer risk (RR = 0.84; 95% CI: 0.74-0.95) with a significantly decreased risk of cancers of the lung and digestive organs. Brothers of a subcohort of 702 index cases showed a markedly increased risk of testicular cancer (RR = 12.3; 95% CI: 3.3-3 1.5). In conclusion, we documented a significantly increased familial risk of testicular cancer which was relatively more pronounced between brothers than between fathers and sons. These findings support the possible involvement of a genetic component in the aetiology of testicular cancer, but also leave room for a hypothesized influence of in-utero exposures, such as specific maternal hormone levels, that might be shared by brothers.

  14. Gorlin-Goltz syndrome in twin brothers: an unusual occurrence with review of the literature.

    Science.gov (United States)

    Anchlia, Sonal; Vyas, Siddharth; Bahl, Sumit; Nagavadiya, Vipul

    2015-08-21

    Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is caused by genetic alteration produced by a mutation in the 'patched' tumour suppressor gene, and is inherited in a dominant autosomal way. Although sporadic cases have been found, this syndrome has rarely been reported in twin patients. The syndrome is characterised by a wide range of developmental abnormalities and has a predisposition to neoplasms such as multiple pigmented basal cell carcinomas and keratocysts in jaws; it also has other features such as palmar and/or plantar pits and calcification of falx cerebri. Owing to the critical oral and maxillofacial manifestations of this syndrome, it is important to recognise its characteristics in order to make a diagnosis, and to plot early preventive treatment and establish the right genetic evidence. Based on a combination of imaging, clinical and histopathological findings, we present a diagnosed case of Gorlin-Goltz syndrome in 18-year-old twin brothers. All cystic lesions were enucleated and 1 year follow-up showed no recurrence. 2015 BMJ Publishing Group Ltd.

  15. [Fragile X syndrome and white matter abnormalities: Case study of two brothers].

    Science.gov (United States)

    Wallach, E; Bieth, E; Sevely, A; Cances, C

    2017-03-01

    Fragile X syndrome is the most usual cause of hereditary intellectual deficiency. Typical symptoms combine intellectual deficiency, social anxiety, intense emotional vigilance, and a characteristic facial dysmorphy. This is subsequent to a complete mutation of the FMR1 gene, considering a semidominant transmission linked to the unstable X. The expansion of the CGG triplet greater than 200 units combined with a high methylation pattern lead to a transcriptional silence of the FMR1 gene, and the protein product, the FMRP, is not synthesized. This protein is involved in synaptic plasticity. Brain MRI can show an increased volume of the caudate nucleus and hippocampus, combined with hypoplasia of the cerebellar vermis. Fragile X Associated Tremor Ataxia Syndrome (FXTAS) syndrome is a neurodegenerative disorder occurring in carriers of the premutation in FMR1. Brain MRI shows an increased T2 signal in the middle cerebellar peduncles. This syndrome is linked to a premutation in the FMR1 gene. We report here the case of two brothers presenting a typical fragile X symptomatology. Brain MRI showed hyperintensities of the middle cerebellar peduncles. Such MRI findings support the assumption of a genetic mosaicism. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  16. Challenging stereotypes? The older woman in the TV series Brothers & Sisters.

    Science.gov (United States)

    Oró-Piqueras, Maricel

    2014-12-01

    The TV series, Brothers & Sisters, broadcast from 2006 to 2011 by ABC (USA) and a year later by Channel 4 (UK) with quite high audience rates, starts when the patriarchal figure, William Walker, dies of a heart attack and two female figures around their sixties come center stage: his wife, Nora Walker, and his long-term lover, Holly Harper. Once the patriarchal figure disappears, the female characters regain visibility by entering the labor market and starting relationships with other men. In that sense, both protagonists experience aging as a time in which they are increasingly freed from social and family constraints. However, their roles as nurturers keep on bringing them back to the domestic space in which they are safe from being involved in uncomfortable and unsuitable situations. Drawing on previous studies on the representation of the older woman in fictional media, this article intends to discern to what extent stereotypes related to the older woman are challenged through the two main protagonists of a contemporary TV series. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Super Mario brothers and sisters: Associations between coplaying video games and sibling conflict and affection.

    Science.gov (United States)

    Coyne, Sarah M; Jensen, Alexander C; Smith, Nathan J; Erickson, Daniel H

    2016-02-01

    Video games can be played in many different contexts. This study examined associations between coplaying video games between siblings and levels of affection and conflict in the relationship. Participants were 508 adolescents (M age = 16.31 years of age, SD = 1.08) who completed questionnaires on video game use and sibling relationships. Participants were recruited from a large Northwestern city and a moderate city in the Mountain West of the United States. Video games played between siblings were coded by an independent sample to assess levels of physical aggression and prosocial behavior in each game. Playing video games with a sibling was associated with higher levels of sibling affection for both boys and girls, but higher levels of conflict for boys only. Playing a violent video game with a brother was associated with lower levels of conflict in the sibling relationship, whereas playing a prosocial video game was not related to any sibling outcome. The value of video games in sibling relationships will be discussed, with a focus on the type of game and the sex of the adolescent. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  18. [Psychotherapy with a boy with depression following the death of his 2 brothers].

    Science.gov (United States)

    Zollinger, R

    1997-12-01

    The author describes the psychotherapy of about 2 1/2 years duration of a 14-year old boy. This psychodynamically oriented psychotherapy dealt with the aftermath of two disasters in his family: The accidental deaths of two older brothers five and four years ago. These events had a lasting effect on the family which negatively interfered with the achievement of developmental tasks in adolescence in the patient. He had erected massive defenses against his own wishes and became withdrawn and depressed. The main issues dealt with in therapy were: (a) The boys fear to step out of his position as the families "child" in consideration of his grieving mother. (b) The boy's difficulty to tolerate and integrate aggressive fantasies and feelings because of his guilt feelings and fear of another loss due to these fantasies and feelings. The working through of conflictual issues in psychotherapy enabled the boy to gain awareness regarding his own needs and wishes, and to find ways to fulfill them. Subsequently, he succeeded in making an adequate professional choice and to go into training for it.

  19. Traits of ADHD and autism in girls with a twin brother

    DEFF Research Database (Denmark)

    Attermann, Jørn; Obel, Carsten; Bilenberg, Niels

    2012-01-01

    It has been hypothesized that prenatal exposure to testosterone may be associated with traits of attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder (ASD). We conducted a population-based study of dizygotic female twins to elucidate this hypothesis, assuming that the sex...... of the co-twin influences the level of prenatal exposure to testosterone. We invited parents of 24,552 3- to 15-year-old twins to answer questionnaires on traits of ADHD and ASD. We analysed the data using a proportional odds model with sex of the co-twin as an instrumental variable for prenatal exposure...... to testosterone of female twins. We received responses for 6,339 girls from dizygotic twin pairs. Odds ratios for male versus female co-twin were 0.71 (95 % confidence interval 0.61-0.81) for ADHD traits and 0.74 (0.66-0.83) for ASD traits, indicating that a twin brother reduces traits of ADHD and ASD in females...

  20. Sixty Days Remaining, Forty Years of CERN, Two Brothers, One Exclusive Interview

    CERN Multimedia

    2001-01-01

    Twins Marcel and Daniel Genolin while sharing memories of their CERN experiences, point out just how much smaller the Meyrin site once was. In a place such as CERN where the physical sciences are in many ways the essence of our daily lives and where technological advancement is an everyday occurrence, it is easy to lose track of the days, months, and even years. But last week twin brothers, Daniel and Marcel Genolin, hired in the early sixties and getting ready to end their eventful forty year CERN experiences, made it clear that the winds of time bluster past us whether we are aware or not. 'CERN was very small when we started' says Marcel, who has worked in transport during his entire time here. A lot has changed. 'When I got here there were no phones in peoples' houses' he recalls,'when there were problems in the control room with the PS (Proton Synchrotron) they used to get a megaphone and tell us {the transport service} to go and get the necessary physicists from their homes in the area. We had to lo...

  1. « Nous sommes tous frères ». Les valeurs des Elephants de Brother, club de baseball professionnel à Taiwan “We are all Brothers”. The Values of Brother Elephants, professional baseball club in Taiwan

    Directory of Open Access Journals (Sweden)

    Jérôme Soldani

    2013-06-01

    Full Text Available À Taiwan, où le baseball est considéré comme le « sport national », les équipes professionnelles sont la propriété de grandes firmes locales et ne sont pas formellement attachées à une municipalité. Ce sont elles-mêmes de petites entreprises qui proposent, en archétype de société, un mode de fonctionnement interne qui repose sur des valeurs autour desquelles se fédèrent leurs supporters. Basée sur une enquête ethnographique de douze mois, notamment au sein de la formation professionnelle des Elephants de Brother, cette contribution montrera comment celle-ci se donne à voir comme une entreprise structurée autour de valeurs morales entendues comme « traditionnelles » et dont les joueurs de l’équipe sont érigés en parangons. Le modèle d’une famille unie et strictement hiérarchisée est mis en exergue par les propriétaires du club et son iconographie. Mais ces représentations se heurtent à la réalité de la pratique quotidienne et aux affaires de corruption qui sapent régulièrement l’image de la ligue professionnelle taiwanaise.In Taiwan, where baseball is considered as the national sport, professional teams are owned by large local firms and are not formally attached to a municipality. They are themselves small companies offering an archetypal society, whose mode of internal operations are based on values around which to unite their fans. Based on an ethnographic study of twelve months, particularly among the professional team of Brother Elephants, this contribution will show how it is to be seen as an enterprise structured around moral values understood as traditional and whose players are established as paragons. The model of a united family and strictly hierarchical is highlighted by the owners of the club and its iconography. But these representations are faced with the reality of daily practice and corruption that regularly undermine the image of the Taiwanese professional league.

  2. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections

    Directory of Open Access Journals (Sweden)

    Xu Xiu

    2012-08-01

    Full Text Available Abstract Background Autistic spectrum disorders (ASDs are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Case presentation Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 – 153,589,577 from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. Conclusions To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

  3. Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages.

    Science.gov (United States)

    Bidon, Tobias; Janke, Axel; Fain, Steven R; Eiken, Hans Geir; Hagen, Snorre B; Saarma, Urmas; Hallström, Björn M; Lecomte, Nicolas; Hailer, Frank

    2014-06-01

    Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained underexplored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390-kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found 1) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, 2) male-biased gene flow across continents and on phylogeographic time scales, and 3) male dispersal that links the Alaskan ABC islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be reevaluated. Recent advances in sequencing technology render the analysis of Y-chromosomal variation feasible, even in nonmodel organisms. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e

  4. Submarine Hydrothermal Activity and Gold-Rich Mineralization at Brothers Volcano, Southern Kermadec Arc, New Zealand

    Science.gov (United States)

    de Ronde, C. E.; Massoth, G. J.; Christenson, B. W.; Butterfield, D. A.; Ishibashi, J.; Hannington, M. D.; Ditchburn, B. G.; Embley, R. W.; Lupton, J. E.; Kamenetsky, D.; Reyes, A. G.; Lahr, J.; Takai, K.

    2006-12-01

    Brothers volcano is one of several hydrothermally active volcanoes that occur along the Kermadec active arc front, NE of New Zealand. It forms an elongate edifice 13 km long by 8 km across that strikes NW-SE. The volcano has a caldera with a basal diameter of ~3 km and a floor at 1,850 m below sea level, surrounded by 290 to 530 m high walls. A volcanic cone of dacite rises 350 m from the caldera floor and partially coalesces with the southern caldera wall. Three hydrothermal sites have been located; on the NW caldera wall, on the SE caldera wall, and on the dacite cone. The NW caldera vent site is a long-term hydrothermal system that is today dominated by evolved seawater but has had episodic injections of magmatic fluid. The SE caldera site represents the main upflow of a relatively well-established magmatic-hydrothermal system on the seafloor where sulfide-rich chimneys are extant. The cone site is a nascent magmatic-hydrothermal system where crack zones localize upwelling acidic waters. Each of these different vent sites represent diverse parts of an evolving hydrothermal system, any one of which may be typical of submarine volcanic arcs. Hydrothermal venting is today occurring at the NW caldera and cone sites. The former is characterized by high-temperature (up to 302°C) venting with pH down to 2.8, low Mg and SO4 values, Cl between 510 and 760 mM, elevated Si and increasing Fe and Mn values with increasing Cl concentrations, consistent with a mostly Cl-enriched endmember. By contrast, vent fluids from the cone site are gas-rich (up to 220 mM total gas), have temperatures 30 ppm) zones in some chimneys formed over a short period of time, coincident with pulses of magmatic fluid into the hydrothermal system.

  5. Hasil Rancang Bangun Sistem ERP dengan SDLC Model Waterfall: Studi Kasus Sistem Inventori PT Pan Brothers, Tbk.

    Directory of Open Access Journals (Sweden)

    Harijanto Pangestu

    2012-12-01

    Full Text Available Competition in the business world effects the use of information technology. To achieve competitive advantage in the global competition, PT Pan Brothers, Tbk. should establish an integrated information system based on ERP (Enterprise Resource Planning. With the ERP system, information will be accurate and up-todate to support strategic decision making. It takes conscientious planning in building the ERP system. Management information systems development projects have a very important role. One determining component is how to choose and use appropriate information systems development method. SDLC (system development life cycle is growing very rapidly along with the development of information technology. It is necessary to choose the right SDLC in building an integrated system based on ERP. Each SDLC models has advantages and disadvantages. SDLC models will only be optimal if used according to the situation and conditions. Waterfall model provides clear deliverables and milestones, good documentation, easy to understand, easy to implement, emphasizes on good procedural workmanship (precoding design. Some of its weaknesses are difficult to integrate risk management, high cost change documents, high administrative costs, often late completion thus.To avoid them, there should be a well-planned project management and steps properly so it can be on time and will not exceed budget.

  6. Financial Contagion in the BRICS Stock Markets: An empirical analysis of the Lehman Brothers Collapse and European Sovereign Debt Crisis

    Directory of Open Access Journals (Sweden)

    DIRCEU PEREIRA

    2018-01-01

    Full Text Available This research analyzes and extends the study of contagion for BRICS emerging stock markets in the context of the last two international financial crises: the Lehman Brothers Bankruptcy Crisis and the European Sovereign Debt Crisis. We investigate changes in the relationship and the co-movements between BRICS markets in response to international shocks that are originated in advanced markets like USA and Europe. Employing data of daily stock market indices of BRICS countries, this research tests for contagion, examining the interactions and characteristics of price movements of BRICS stock markets by applying cointegration, causality and VECM/Gonzalo-Granger statistic and variance decomposition methodology on stock returns as a measure of perceived country risk. The results exhibit that both long-run and short-run relationships patterns exist between BRICS stock markets and have drastically changed during turbulent periods compared with tranquil period, pointing towards the occurrence of contagion phenomenon among BRICS markets during the last two crises. These findings also indicate that changes in the USA and the Euro Zone indices affect BRICS stock markets in the short-run, acting as a leading indicator for investing in BRICS markets. Also imply an increasing degree of global market integration, bringing major implications for portfolio diversification and policy makers.

  7. A Clarion Call for Social Work Attention: Brothers and Sisters of Persons With Acquired Brain Injury in the United States.

    Science.gov (United States)

    Degeneffe, Charles Edmund

    2016-08-11

    This article presents a clarion call for increased social work attention to the needs of siblings of persons with acquired brain injury (ABI) in the United States. The article overviews how siblings are psychosocially affected, how they provide care to the injured brothers and sisters, and how they personally develop as a result of their experiences. The article highlights the fact that social workers and other professionals often overlook the needs of siblings of persons with ABI and makes an appeal for social workers to advance clinical practice and research to benefit this often neglected population.

  8. Cognitive ability in young adulthood and risk of dementia in a cohort of Danish men, brothers, and twins

    DEFF Research Database (Denmark)

    Osler, Merete; Christensen, Gunhild T; Garde, Ellen

    2017-01-01

    INTRODUCTION: We examined the association between cognitive ability in young adulthood and dementia in Danish men, brothers, and male twins. METHODS: In total, 666,986 men born between 1939 and 1959 were identified for dementia diagnosis in national registries from 1969 to 2016. The association.......03-1.13]). The intrabrother and twin analyses (taking shared family factors into account) showed attenuated risk estimates but with wide CIs. DISCUSSION: Low early-life cognitive ability increases the risk of dementia before the age of 78 years. The association is partly explained by shared family factors....

  9. Ter um irmão especial: convivendo com a Síndrome de Down Having a special brother/sister: living together with the Down Syndrome

    Directory of Open Access Journals (Sweden)

    Eucia Beatriz Lopes Petean

    2005-12-01

    Full Text Available O presente estudo teve por objetivos conhecer como é a relação entre irmãos mais velhos de pessoas com diagnóstico de Síndrome de Down (SD; que informações e sentimentos possuem sobre o diagnóstico; se houve ou não modificações na dinâmica familiar e em suas próprias vidas. Foram entrevistadas 11 pessoas, de ambos os sexos, com idade superior a dez anos, sendo, cada uma, o irmão mais velho de criança com diagnóstico de SD, sendo realizada análise quantitativa de dados da amostra e análise quantitativa-interpretativa e qualitativa para os dados da entrevista. Os dados mostram que a maioria dos sujeitos (90,9% sabe o nome da Síndrome e foram informados pela mãe logo após o nascimento do irmão, seis deles consideram que reagiram normalmente à notícia. Quanto às responsabilidades adquiridas, a maioria, 90,9%, são responsáveis pelas atividades de vida diária; 27,27% deles consideram que houve acréscimo de responsabilidade em suas vidas em decorrência do nascimento do irmão com SD. Em relação ao sentimento que apresentam por terem um irmão especial, 54,54% consideram como positivo, ou seja, disseram que também sentem-se especiais. Na falta (morte dos pais, a metade dos participantes informa que eles serão os responsáveis legais deste irmão. Pode-se concluir que o nascimento de um irmão com SD tem conseqüências na rotina de vida dos irmãos mais velhos, trazendo modificações e responsabilidades para eles. Entretanto, parece ter um efeito menos dirigido para a desestrutura psicológica, sendo poucas as manifestações de sentimentos extremos, ficando apenas no nível da tristeza, quando são expressos.The present study intended to know about the relation among older brothers/sisters of people with a diagnosis of Down Syndrome (DS, regarding to information and feelings they have about this diagnosis, and if changes have occurred within family dynamics and their own lives. Eleven people were interviewed, from

  10. Palmo-Plantar hyperkeratosis, intellectual disability, and spastic paraplegia in two maternal half brothers: further evidence for an X-linked inheritance.

    Science.gov (United States)

    Isidor, Bertrand; Lefebvre, Tiphaine; Barbarot, Sébastien; Perrier, Julie; Mercier, Sandra; Péréon, Yann; Le Caignec, Cédric; David, Albert

    2013-06-01

    In 1983, Fitzsimmons et al. reported four brothers with an unrecognized disorder characterized by intellectual disability, spastic paraplegia, and palmo-plantar hyperkeratosis (OMIM 309500). In this report, we describe a family in which two males, maternal half-brothers, had learning disabilities. Both patients also showed spasticity in the lower limbs and palmo-plantar hyperkeratosis. The mother of the affected boys had learning difficulties but did not show any dermatological symptoms. This report confirms that the association of features reported by Fitzsimmons et al. is a distinct entity and further suggests an X-linked mode of inheritance. Copyright © 2013 Wiley Periodicals, Inc.

  11. On the Use of Sibiling Data to Estimate the Effects of Family Background, Cognitive Skills, and Schooling: Results from the Kalamazoo Brothers Study. Discussion Papers 374-76.

    Science.gov (United States)

    Olneck, Michael R.

    Sibling data drawn from the Kalamazoo Brothers sample are used in this report to assess the adequacy of conventional sociological variables for measuring family background, to estimate the overall effects of family background on test scores, education, occupational status, and earning, and to control family background when estimating the effects…

  12. "My Brother Likes Meeting New People, but Don't Ask Him Any Direct Questions": Involving Adults with Autism plus Learning Disability in a Qualitative Research Project

    Science.gov (United States)

    Tozer, Rosemary; Atkin, Karl; Wenham, Aniela

    2014-01-01

    Adult siblings of people with autism and a learning disability have hitherto been largely overlooked by research, policy and practice in the UK. As part of a qualitative study focussing on adult siblings, we met twelve people with autism plus severe learning disability with their brother or sister. Individually tailored resources were used to make…

  13. Adolescent Siblings of Individuals with and without Intellectual and Developmental Disabilities: Self-Reported Empathy and Feelings about Their Brothers and Sisters

    Science.gov (United States)

    Shivers, Carolyn M.; Dykens, Elisabeth M.

    2017-01-01

    Siblings of brothers or sisters with intellectual and developmental disabilities (IDD) are important but understudied family members. As many previous studies have relied on parent report of sibling outcomes, the use of sibling self-report is an important addition to the research. This study assessed the feelings of adolescent siblings toward…

  14. Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

    NARCIS (Netherlands)

    Eeten, E. van; Faber, H.T.; Kunst, D.

    2017-01-01

    We report the case of two young brothers with Epstein-Barr virus (EBV) otomastoiditis complicated by a facial nerve paralysis. The boys, aged 7 months (patient A) and 2 years and 8 months (patient B), were diagnosed with a facial nerve paralysis House-Brackmann (HB) grade IV (A) and V (B). After

  15. "I like that He Always Shows Who He Is": The Perceptions and Experiences of Siblings with a Brother with Autism Spectrum Disorder

    Science.gov (United States)

    Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Dowey, Alan; Reilly, Deirdre

    2009-01-01

    Semi-structured interviews were used to explore the perceptions and experiences of eight typically developing siblings in middle childhood who had a brother with autism spectrum disorder (ASD). The interviews were analysed using interpretative phenomenological analysis (IPA). The analysis yielded five main themes: (i) siblings' perceptions of the…

  16. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty

    DEFF Research Database (Denmark)

    Känsäkoski, Johanna; Raivio, Taneli; Juul, Anders

    2015-01-01

    BACKGROUND: Idiopathic central precocious puberty (ICPP) results from the premature reactivation of the hypothalamic-pituitary-gonadal axis leading to development of secondary sexual characteristics prior to 8 y in girls or 9 y in boys. Since the initial discovery of mutations in the maternally...... hypothalamic complementary DNA (cDNA) was investigated by PCR. RESULTS: One paternally inherited rare variant, c.1034G>A (p.Arg345His), was identified in one girl with ICPP and in her brother with early puberty. The variant is predicted to be deleterious by three different in silico prediction programs....... Expression of MKRN3 was confirmed in adult human hypothalamus. CONCLUSION: Our results are in line with previous studies in which paternally inherited MKRN3 mutations have been found both in males and in females with ICPP or early puberty. Our report further expands the set of MKRN3 mutations identified...

  17. The paths of salvation and eternal condemnation: The presence of the allegory in the History of the Elected Pilgrim and his Brother Precito (1682, de Alexandre de Gusmão

    Directory of Open Access Journals (Sweden)

    José Adriano Filho

    2015-04-01

    Full Text Available The repercussions of the echoes of the Council of Trent (1546-1563, the Counter Reform movement, and the repercussions they had on the artistic production in the Catholic world. The pedagogical-didactic intents behind its composition are grounded on the belief that art could be an effective tool for reconverting of the faithful and for indoctrination in the values of the Catholic faith. Considering that, this paper aims at presenting the way allegory became an important tool for the interpretation and construction of religious discourse, as we can see in the History of the Elected Pilgrim and his Brother Precito. The book is an allegorical narrative that presents the history of two pilgrim brothers born in Egypt from where they set out with the intention of making a fortune (one brother goes to Jerusalem, and the  other one goes to Babylon. In this way, the book presents continuity with the medieval pattern that highlights the journey, especially the path for salvation. The readiness of allegory to transmit abstract concepts through concrete visualizations allied to a form of indirect expression made it a powerful, didactic, apologetic, and entertaining tool for that time.

  18. A novel AVPR2 splice site mutation leads to partial X-linked nephrogenic diabetes insipidus in two brothers.

    Science.gov (United States)

    Schernthaner-Reiter, Marie Helene; Adams, David; Trivellin, Giampaolo; Ramnitz, Mary Scott; Raygada, Margarita; Golas, Gretchen; Faucz, Fabio R; Nilsson, Ola; Nella, Aikaterini A; Dileepan, Kavitha; Lodish, Maya; Lee, Paul; Tifft, Cynthia; Markello, Thomas; Gahl, William; Stratakis, Constantine A

    2016-05-01

    X-linked nephrogenic diabetes insipidus (NDI, OMIM#304800) is caused by mutations in the arginine vasopressin (AVP, OMIM*192340) receptor type 2 (AVPR2, OMIM*300538) gene. A 20-month-old boy and his 8-year-old brother presented with polyuria, polydipsia, and failure to thrive. Both boys demonstrated partial DDAVP (1-desamino-8-D AVP or desmopressin) responses; thus, NDI diagnosis was delayed. While routine sequencing of AVPR2 showed a potential splice site variant, it was not until exome sequencing confirmed the AVPR2 splice site variant and did not reveal any more likely candidates that the patients' diagnosis was made and proper treatment was instituted. Both patients were hemizygous for two AVPR2 variants predicted in silico to affect AVPR2 messenger RNA (mRNA) splicing. A minigene assay revealed that the novel AVPR2 c.276A>G mutation creates a novel splice acceptor site leading to 5' truncation of AVPR2 exon 2 in HEK293 human kidney cells. Both patients have been treated with high-dose DDAVP with a remarkable improvement of their symptoms and accelerated linear growth and weight gain. We present here a unique case of partial X-linked NDI due to an AVPR2 splice site mutation; patients with diabetes insipidus of unknown etiology may harbor splice site mutations that are initially underestimated in their pathogenicity on sequence analysis. • X-linked nephrogenic diabetes insipidus is caused by AVPR2 mutations, and disease severity can vary depending on the functional effect of the mutation. What is New: • We demonstrate here that a splice site mutation in AVPR2 leads to partial X-linked NDI in two brothers. • Treatment with high-dose DDAVP led to improvement of polyuria and polydipsia, weight gain, and growth.

  19. Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: A 'Big Brother' evaluation

    International Nuclear Information System (INIS)

    Steenbakkers, Roel J.H.M.; Duppen, Joop C.; Fitton, Isabelle; Deurloo, Kirsten E.I.; Zijp, Lambert; Uitterhoeve, Apollonia L.J.; Rodrigus, Patrick T.R.; Kramer, Gijsbert W.P.; Bussink, Johan; Jaeger, Katrien De; Belderbos, Jose S.A.; Hart, Augustinus A.M.; Nowak, Peter J.C.M.; Herk, Marcel van; Rasch, Coen R.N.

    2005-01-01

    Background and purpose: To evaluate the process of target volume delineation in lung cancer for optimization of imaging, delineation protocol and delineation software. Patients and methods: Eleven radiation oncologists (observers) from five different institutions delineated the Gross Tumor Volume (GTV) including positive lymph nodes of 22 lung cancer patients (stages I-IIIB) on CT only. All radiation oncologist-computer interactions were recorded with a tool called 'Big Brother'. For each radiation oncologist and patient the following issues were analyzed: delineation time, number of delineated points and corrections, zoom levels, level and window (L/W) settings, CT slice changes, use of side windows (coronal and sagittal) and software button use. Results: The mean delineation time per GTV was 16 min (SD 10 min). The mean delineation time for lymph node positive patients was on average 3 min larger (P=0.02) than for lymph node negative patients. Many corrections (55%) were due to L/W change (e.g. delineating in mediastinum L/W and then correcting in lung L/W). For the lymph node region, a relatively large number of corrections was found (3.7 corr/cm 2 ), indicating that it was difficult to delineate lymph nodes. For the tumor-atelectasis region, a relative small number of corrections was found (1.0 corr/cm 2 ), indicating that including or excluding atelectasis into the GTV was a clinical decision. Inappropriate use of L/W settings was frequently found (e.g. 46% of all delineated points in the tumor-lung region were delineated in mediastinum L/W settings). Despite a large observer variation in cranial and caudal direction of 0.72 cm (1 SD), the coronal and sagittal side windows were not used in 45 and 60% of the cases, respectively. For the more difficult cases, observer variation was smaller when the coronal and sagittal side windows were used. Conclusions: With the 'Big Brother' tool a method was developed to trace the delineation process. The differences between

  20. Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families.

    Science.gov (United States)

    Arteaga-Vázquez, Jazmín; López-Hernández, María A; Svyryd, Yevgeniya; Mutchinick, Osvaldo M

    2015-12-01

    Androgenetic alopecia (AGA) or common baldness is the most prevalent form of hair loss in males. Familial predisposition has been recognized, and heritability estimated in monozygotic twins suggests an important genetic predisposition. Several studies indicate that the numbers of CAG/GGC repeats in exon 1 of the androgen receptor gene (AR) maybe associated with AGA susceptibility. To investigate a possible correlation between AR CAG/GGC haplotypes and the presence or not of alopecia in sibships with two or more brothers among them at least one of them has AGA. Thirty-two trios including an alopecic man, one brother alopecic or not, and their mother were enrolled. Sanger sequencing of the exon 1 of the AR gene was conducted to ascertain the number of CAG/GGC repeats in each individual. Heterozygous mother for the CAG/GGC haplotypes was an inclusion criterion to analyze the segregation haplotype patterns in the family. Concordance for the number of repeats and AGA among brothers was evaluated using kappa coefficient and the probability of association in the presence of genetic linkage between CAG and GGC repeats and AGA estimated by means of the family-based association test (FBAT). The median for the CAG and GGC repeats in the AR is similar to that reported in other populations. The CAG/GGC haplotypes were less polymorphic than that reported in other studies, especially due to the GGC number of repeats found. Kappa coefficient resulted in a concordance of 37.3% (IC 95%, 5.0-69.0%) for the AGA phenotype and identical CAG/GGC haplotypes. There was no evidence of linkage disequilibrium. Our results do not confirm a possible correlation or linkage disequilibrium between the CAG/GGC haplotypes of the AR gene and androgenetic alopecia in Mexican brothers. © 2015 Wiley Periodicals, Inc.

  1. Non-marfan idiopathic medionecrosis (cystic medial necrosis) presenting with multiple visceral artery aneurysms and diffuse connective tissue fragility: Two brothers

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, Jun [Gunma University School of Medicine, Department of Nuclear Medicine (Japan); Tsunemura, Mami [Gunma University School of Medicine, Department of Diagnostic Radiology (Japan); Amano, Shigeko [Gunma University School of Medicine, Department of Nuclear Medicine (Japan); Tokizawa, Shigemi [Gunma University School of Medicine, Department of Hygiene and Virology (Japan); Oowada, Susumu [Gunma University School of Medicine, Department of Second Surgery (Japan); Shinkai, Hiroko [Gunma Health Foundation (Japan); Maehara, Yasunobu [Gunma University School of Medicine, Department of Diagnostic Radiology (Japan); Endo, Keigo [Gunma University School of Medicine, Department of Nuclear Medicine (Japan)

    1997-05-15

    Two brothers with multiple visceral artery aneurysms or dilatations and diffuse connective tissue fragility who did not have clinical features of Marfan syndrome are reported. One presented with retroperitoneal hemorrhage during angiography, and idiopathic medionecrosis was proved by resection of the aneurysms. These cases belong to the heterogeneous group of Marfan syndrome. The angiographical features (multiple dilation of visceral arteries) suggests fragility of connective tissue and is predictive of hazards during and after a catheterization and operation.

  2. Metabolic syndrome, hypertension, and hyperlipidemia in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis.

    Science.gov (United States)

    Yilmaz, Bulent; Vellanki, Priyathama; Ata, Baris; Yildiz, Bulent Okan

    2018-02-01

    To provide an evidence-based assessment of metabolic syndrome, hypertension, and hyperlipidemia in first-degree relatives of women with polycystic ovary syndrome (PCOS). Systematic review and meta-analysis. Not applicable. Mothers, fathers, sisters, and brothers of women with and without PCOS. An electronic-based search with the use of PubMed from 1960 to June 2015 and cross-checked references of relevant articles. Metabolic syndrome, hypertension and dyslipidemia, and surrogate markers, including systolic blood pressure (BP), diastolic BP, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Fourteen of 3,346 studies were included in the meta-analysis. Prevalence of the following was significantly increased in relatives of women with PCOS: metabolic syndrome (risk ratio [RR] 1.78 [95% confidence interval 1.37, 2.30] in mothers, 1.43 [1.12, 1.81] in fathers, and 1.50 [1.12, 2.00] in sisters), hypertension (RR 1.93 [1.58, 2.35] in fathers, 2.92 [1.92, 4.45] in sisters), and dyslipidemia (RR 3.86 [2.54, 5.85] in brothers and 1.29 [1.11, 1.50] in fathers). Moreover, systolic BP (mothers, sisters, and brothers), total cholesterol (mothers and sisters), low-density lipoprotein cholesterol (sisters), and triglycerides (mothers and sisters) were significantly higher in first-degree relatives of PCOS probands than in controls. Our results show evidence of clustering for metabolic syndrome, hypertension, and dyslipidemia in mothers, fathers, sisters, and brothers of women with PCOS. PROSPERO 2016 CRD42016048557. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Non-marfan idiopathic medionecrosis (cystic medial necrosis) presenting with multiple visceral artery aneurysms and diffuse connective tissue fragility: Two brothers

    International Nuclear Information System (INIS)

    Kubota, Jun; Tsunemura, Mami; Amano, Shigeko; Tokizawa, Shigemi; Oowada, Susumu; Shinkai, Hiroko; Maehara, Yasunobu; Endo, Keigo

    1997-01-01

    Two brothers with multiple visceral artery aneurysms or dilatations and diffuse connective tissue fragility who did not have clinical features of Marfan syndrome are reported. One presented with retroperitoneal hemorrhage during angiography, and idiopathic medionecrosis was proved by resection of the aneurysms. These cases belong to the heterogeneous group of Marfan syndrome. The angiographical features (multiple dilation of visceral arteries) suggests fragility of connective tissue and is predictive of hazards during and after a catheterization and operation

  4. THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877) BY FYODOR DOSTOEVSKY

    OpenAIRE

    Elena A. Fedorova

    2015-01-01

    The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Kara...

  5. Sounding the Bromance: The Chopstick Brothers' 'Little Apple' music video, genre, gender and the search for meaning in Chinese popular music

    OpenAIRE

    Stock, Jonathan P. J.

    2016-01-01

    This article analyses the music video of ‘Little Apple’ by Wang Taili and Xiao Yang, also known as the Chopstick Brothers, one of China’s most successful productions in 2014, and one that exemplifies certain emerging trends in Chinese popular music more generally. The music video draws on K-pop models but also on Western inspirations (biblical, historical and contemporary) and has proven hard to reduce to a single, definitive narrative or interpretation. The analysis proceeds by introducing t...

  6. [Sense of coherence and ways of coping in the relationship with brother or sister in healthy siblings of mentally ill persons].

    Science.gov (United States)

    Osuchowska-Kościjańska, Anna; Charzyńska, Katarzyna; Chadzyńska, Małgorzata; Drozdzyńska, Anna; Kasperek-Zimowska, Beata; Bednarek, Agata; Sawicka, Maryla

    2014-01-01

    The aim of the present study was to investigate sense of coherence in healthy siblings of persons suffering from schizophrenia as well as their ways of coping in the relationship with ill brother or sister. 40 healthy brothers and sisters of persons with ICD- 10 diagnosis of F20 to F29 participated in the present study. Orientation to Life Scale (SOC- 29) was used to assess sense of coherence and Ways of Coping with Stress questionnaire (SRSS) was used to examine stress coping strategies. Mean global score of siblings of persons with schizophrenia was 111 points. Subjects used coping strategies focused on problem significantly more often than those focused on emotions. Therapeutic work with healthy siblings should focus on strengthening sense of personal competence, development of personal resources and different ways of coping with stress, investigation of emotions that healthy siblings experience in the relationship with ill brother or sister as well as supporting the process of accepting changes in the relationship with the ill sibling.

  7. A dictionary without definitions: romanticist science in the production and presentation of the Grimm brothers' German dictionary, 1838-1863.

    Science.gov (United States)

    Kistner, Kelly

    2014-12-01

    Between 1838 and 1863 the Grimm brothers led a collaborative research project to create a new kind of dictionary documenting the history of the German language. They imagined the work would present a scientific account of linguistic cohesiveness and strengthen German unity. However, their dictionary volumes (most of which were arranged and written by Jacob Grimm) would be variously criticized for their idiosyncratic character and ultimately seen as a poor, and even prejudicial, piece of scholarship. This paper argues that such criticisms may reflect a misunderstanding of the dictionary. I claim it can be best understood as an artifact of romanticist science and its epistemological privileging of subjective perception coupled with a deeply-held faith in inter-subjective congruence. Thus situated, it is a rare and detailed case of Romantic ideas and ideals applied to the scientific study of social artifacts. Moreover, the dictionary's organization, reception, and legacy provide insights into the changing landscape of scientific practice in Germany, showcasing the difficulties of implementing a romanticist vision of science amidst widening gaps between the public and professionals, generalists and specialists.

  8. Deception and the death of Ilyusha: truth and the best interest of a dying child in The Brothers Karamazov.

    Science.gov (United States)

    Martin, Clancy

    2014-10-01

    For centuries, many physicians and parents assumed that it was ethically justifiable to lie to a dying child. The reasoning was clear. Because the lie would likely eliminate or prevent a concrete harm (the child's fear), and the lie is about a harm that is unavoidable anyway, a lie appeared to be the morally desirable thing to do. Today, the ethical consensus has shifted. Many doctors and other health professionals now argue that we have an obligation to tell children the cold, hard truth. In this article, I argue that "the cold, hard truth" (assuming we can know it with certainty) might not always be in the best interest of the patient. To illustrate the point, I analyze an episode in Dostoevsky's novel, The Brothers Karamazov, in which a child is dying, his father lies to him about it, and 2 doctors take very different approaches to the truth. Each of these individuals has a particular interest when it comes to the question of "the truth" about the death of Ilyusha. I use this story to ask whether it is ethically permissible to lie to a dying child and, if so, who has the moral authority to tell that lie. Copyright © 2014 by the American Academy of Pediatrics.

  9. Columbia River wildlife mitigation habitat evaluation procedures report: Scotch Creek Wildlife Area, Berg Brothers, and Douglas County pygmy rabbit projects

    International Nuclear Information System (INIS)

    Ashley, P.R.; Ratassepp, J.; Berger, M.; Judd, S.L.

    1997-01-01

    This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites

  10. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty.

    Science.gov (United States)

    Känsäkoski, Johanna; Raivio, Taneli; Juul, Anders; Tommiska, Johanna

    2015-12-01

    Idiopathic central precocious puberty (ICPP) results from the premature reactivation of the hypothalamic-pituitary-gonadal axis leading to development of secondary sexual characteristics prior to 8 y in girls or 9 y in boys. Since the initial discovery of mutations in the maternally imprinted MKRN3 gene in 2013, several case reports have described mutations in this gene in ICPP patients from different populations, highlighting the importance of MKRN3 as a regulator of pubertal onset. We screened 29 Danish girls with ICPP for mutations in MKRN3. Expression of MKRN3 in human hypothalamic complementary DNA (cDNA) was investigated by PCR. One paternally inherited rare variant, c.1034G>A (p.Arg345His), was identified in one girl with ICPP and in her brother with early puberty. The variant is predicted to be deleterious by three different in silico prediction programs. Expression of MKRN3 was confirmed in adult human hypothalamus. Our results are in line with previous studies in which paternally inherited MKRN3 mutations have been found both in males and in females with ICPP or early puberty. Our report further expands the set of MKRN3 mutations identified in ICPP patients across diverse populations, thus supporting the major regulatory function of MKRN3 in pubertal onset.

  11. A novel homozygous AP4B1 mutation in two brothers with AP-4 deficiency syndrome and ocular anomalies.

    Science.gov (United States)

    Accogli, Andrea; Hamdan, Fadi F; Poulin, Chantal; Nassif, Christina; Rouleau, Guy A; Michaud, Jacques L; Srour, Myriam

    2018-04-01

    Adaptor protein complex-4 (AP-4) is a heterotetrameric protein complex which plays a key role in vesicle trafficking in neurons. Mutations in genes affecting different subunits of AP-4, including AP4B1, AP4E1, AP4S1, and AP4M1, have been recently associated with an autosomal recessive phenotype, consisting of spastic tetraplegia, and intellectual disability (ID). The overlapping clinical picture among individuals carrying mutations in any of these genes has prompted the terms "AP-4 deficiency syndrome" for this clinically recognizable phenotype. Using whole-exome sequencing, we identified a novel homozygous mutation (c.991C>T, p.Q331*, NM_006594.4) in AP4B1 in two siblings from a consanguineous Pakistani couple, who presented with severe ID, progressive spastic tetraplegia, epilepsy, and microcephaly. Sanger sequencing confirmed the mutation was homozygous in the siblings and heterozygous in the parents. Similar to previously reported individuals with AP4B1 mutations, brain MRI revealed ventriculomegaly and white matter loss. Interestingly, in addition to the typical facial gestalt reported in other AP-4 deficiency cases, the older brother presented with congenital left Horner syndrome, bilateral optic nerve atrophy and cataract, which have not been previously reported in this condition. In summary, we report a novel AP4B1 homozygous mutation in two siblings and review the phenotype of AP-4 deficiency, speculating on a possible role of AP-4 complex in eye development. © 2018 Wiley Periodicals, Inc.

  12. Columbia River Wildlife Mitigation Habitat Evaluation Procedures Report / Scotch Creek Wildlife Area, Berg Brothers, and Douglas County Pygmy Rabbit Projects.

    Energy Technology Data Exchange (ETDEWEB)

    Ashley, Paul R.

    1997-01-01

    This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites.

  13. Terapia de linguagem de irmãos com transtornos invasivos do desenvolvimento: estudo longitudinal Language therapy of brothers with pervasive developmental disorders: longitudinal study

    Directory of Open Access Journals (Sweden)

    Andréa Regina Nunes Misquiatti

    2010-01-01

    Full Text Available O objetivo deste trabalho foi descrever o processo de intervenção fonoaudiológica de dois irmãos com transtornos invasivos do desenvolvimento, por meio de um estudo longitudinal de caso clínico. Participaram dois irmãos, um de nove e outro de 11 anos de idade, ambos do gênero masculino, com autismo (Caso 1 e transtorno invasivo do desenvolvimento sem outra especificação (Caso 2. Como procedimento de coleta e análise de dados foi realizado um estudo longitudinal, por meio de acompanhamento dos casos ao longo de quatro anos de intervenção fonoaudiológica. Foram realizadas filmagens durante as sessões de terapia, análise documental de informações dos prontuários referentes à anamnese, avaliação e relatórios terapêuticos fonoaudiológicos, exames e avaliações multidisciplinares. Em ambos os casos houve melhora no contato visual, na interação social, no vocabulário e na brincadeira simbólica. No Caso 1 ocorreu aumento de 2,0 para 6,2 atos comunicativos por minuto, no Caso 2 de 3,5 para 8,0 atos e ambos demonstraram predominância do meio verbal e maior variedade de funções comunicativas. Outros fatores influenciaram estes resultados, como a deficiência intelectual, a dinâmica familiar, os conflitos no relacionamento entre os irmãos e o ambiente escolar em que estavam inseridos. Confirmou-se a relevância do fonoaudiólogo em intervenções nos transtornos invasivos do desenvolvimento, junto a equipes multidisciplinares, para a discussão diagnóstica e de condutas mais adequadas. Estudos longitudinais podem contribuir para uma análise mais detalhada e fidedigna de intervenções terapêuticas nesses casos, para esclarecer lacunas existentes na literatura e subsidiar a atuação do fonoaudiólogo clínico.The aim of this research was to describe the language intervention process of two brothers with pervasive developmental disorders, through a longitudinal clinical case study. Two brothers - one nine and the other 11

  14. A Significant Source for the Madeleine and Other Major Episodes in Combray: Proust's Intertextual Use of Pierre Loti's My Brother Yves

    Directory of Open Access Journals (Sweden)

    Richard M. Berrong

    2014-01-01

    Full Text Available The most famous passage in Marcel Proust’s In Search of Lost Time , and one of the most famous passages in Western literature, is the moment when the narrator sips tea while eating a shell-shaped pastry called a madeleine and suddenly recalls very vividly an apparently long-forgotten scene from his childhood. From this episode Proust developed his theories about involuntary memory and its important role in our emotional welfare. Proust was an avid reader of the French novelist Pierre Loti when he was young. Contemporary accounts show that he was able to recite whole passages from Loti’s work in public from memory. This article demonstrates the extent to which Proust made intertextual use of scenes from Loti’s novel My Brother Yves in constructing the madeleine and other famous passages in Combray , the first section of In Search of Lost Time. It does not attempt to question the originality of Proust’s work. Rather, building on previous studies of intertextuality in Proust, it seeks to show how the author went about creating his work and dialoguing with at least some of his potential contemporary readers.

  15. THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877 BY FYODOR DOSTOEVSKY

    Directory of Open Access Journals (Sweden)

    Elena A. Fedorova

    2015-11-01

    Full Text Available The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Karamazov” (in particular on the chapter “Th e Russian Monk”. As follows from the comparison of the texts the dominant qualities of the ideal image of a Russian saint are repentance, humility and suff ering, desire for purifi cation, spiritual ability to resist the evil. The ideal form of existence of Russian people becomes conciliarism. The type of historicism is the movement to the Last Judgment. Gospel allusions and metaphors reinforce the author’s interpretation. Th us, Dostoevsky carries on the dialogue with the evangelical word at an ideological, imaginative, genre, motive and narrative level of the text. Th e hallmark of the works of Fyodor Dostoevsky who followed the evangelical tradition, becomes a dialogical word.

  16. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections.

    Science.gov (United States)

    Xu, Xiu; Xu, Qiong; Zhang, Ying; Zhang, Xiaodi; Cheng, Tianlin; Wu, Bingbing; Ding, Yanhua; Lu, Ping; Zheng, Jingjing; Zhang, Min; Qiu, Zilong; Yu, Xiang

    2012-08-21

    Autistic spectrum disorders (ASDs) are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 - 153,589,577) from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

  17. Driver’s Big Brother: How Smartphones Can Increase Driver’s Awareness

    Directory of Open Access Journals (Sweden)

    Ashraf Khalil

    2012-10-01

    Full Text Available Using mobile devices while driving has been widely shown to pose serious safety risk. Various approaches aim at mitigating the risk of mobile devices while driving. Some initiatives have focused on increasing drivers’ awareness of such potential risk. Along the same vein, we present a model, and its implementation, for assessing the degree of distraction that drivers experience while using phones during driving. Based on data collected during each driving session, the application gives statistics, such as keypad interaction, number and length of phone calls and the driving speed, to the driver. This should increase the awareness of drivers by helping them understand how much distraction they got involved with during driving and how much hazardous they can be to themselves and to others. Our experiments with drivers demonstrated the potential of the application at highlighting risky behavior, promoting awareness and motivating better driving.

  18. Two Silent Brothers. Althusser and Foucault at the Crossroads of Ideology

    Directory of Open Access Journals (Sweden)

    Diego Melegari

    2014-07-01

    Full Text Available The article aims to reinterpret the relationship between Louis Althusser and Michel Foucault on the specific ground of the notion of "Ideology." If Foucault's critique addresses initially the alleged opposition between ideological discourse and scientific discourse, this does not seem to fade in the seventies, despite the convergence of Foucault's "microphysics of power"with Althusser's insistence on the "material" character of ideology. To explain the persistence of this comparison and of this tension the author shows how with it are involved highly problematic knots for the whole Foucault's thought: the status of representation and truth, the inner existence and temporality of capitalism and, in particular, the relationship between criticism and politics.

  19. O PROCESSO CRIATIVO EM THE BROTHER, DE ROBERT COOVER: UMA RELEITURA DO SAGRADO NA CONTEMPORANEIDADE

    Directory of Open Access Journals (Sweden)

    Fernanda Aquino Sylvestre

    2014-05-01

    Full Text Available Robert Coover é um importante escritor norte-americano preocupado com as perspectivas sociais, psicológicas, econômicas e políticas contemporâneas e com o modo como elas se configuram na formação da sociedade do seu país. Essa preocupação se reflete tanto nas técnicas de construção de suas histórias, quanto nas críticas apresentadas em suas narrativas. O trabalho em questão discute a reescrita que Coover faz de mitos bíblicos dentro do contexto pós-moderno, globalizado, compondo novos textos que subvertem os elementos tradicionais da narrativa. Mais especificamente, este artigo analisa a reescrita que o autor norte-americano empreende acerca da passagem bíblica da Arca de Noé no conto “The Brother”.

  20. Big Brothers: hegemonía mediática en el proceso electoral de 2006

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    Jorge Balderas Domínguez

    2007-01-01

    Full Text Available El presente artículo analiza la manera en que la televisión mexicana cubrió el proceso electoral de 2006. Aborda también los vínculos de las dos principales empresas con las élites hegemónicas del país, ya sean éstas económicas o políticas, dependiendo la coyuntura histórica. A su vez, intenta desarrollar un análisis crítico basado en estudios teóricos sobre la función social de los medios, particularmente, de la omnipresencia de la televisión que pareciera erigirse en el Gran Hermano (que te vigila, en una nueva especie de mundo orwelliano.

  1. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Harrington, Deirdre M.

    2011-10-28

    Abstract Background Adolescent females have been highlighted as a particularly sedentary population and the possible negative effects of a sedentary lifestyle are being uncovered. However, much of the past sedentary research is based on self-report or uses indirect methods to quantity sedentary time. Total time spent sedentary and the possible intricate sedentary patterns of adolescent females have not been described using objective and direct measure of body inclination. The objectives of this article are to examine the sedentary levels and patterns of a group of adolescent females using the ActivPAL™ and to highlight possible differences in sedentary levels and patterns across the week and within the school day. A full methodological description of how the data was analyzed is also presented. Methods One hundred and eleven adolescent females, age 15-18 yrs, were recruited from urban and rural areas in the Republic of Ireland. Participants wore an ActivPAL physical activity monitor for a 7.5 day period. The ActivPAL directly reports total time spent sitting\\/lying every 15 seconds and accumulation (frequency and duration) of sedentary activity was examined using a customized MATLAB ® computer software programme. Results While no significant difference was found in the total time spent sitting\\/lying over the full 24 hour day between weekday and weekend day (18.8 vs. 18.9 hours; p = .911), significantly more sedentary bouts of 1 to 5 minutes and 21 to 40 minutes in duration were accumulated on weekdays compared to weekend days (p < .001). The mean length of each sedentary bout was also longer (9.8 vs. 8.8 minutes; p < .001). When school hours (9 am-3 pm) and after school hours (4 pm-10 pm) were compared, there was no difference in total time spent sedentary (3.9 hours; p = .796) but the pattern of accumulation of the sedentary time differed. There were a greater number of bouts of > 20 minutes duration during school hours than after school hours (4.7 vs. 3

  2. Severe protein-calorie malnutrition in two brothers due to abuse by starvation

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    Marcela Montenegro Braga Barroso

    Full Text Available Abstract Objective: To describe the case of two siblings with severe protein-calorie malnutrition due to abuse by starvation. Cases description: The two patients were simultaneously referred to the Hospital Municipal, where they were admitted to the Pediatric Gastroenterology clinic of a university hospital for diagnostic investigation of the cause of severe malnutrition and screening tests for Celiac Disease, Cystic Fibrosis and Environmental enteropathy among others. The exams were all normal, and after detailed research on the interactions of this family, we reached the conclusion that the malnutrition was due to abuse by starvation. The children spent approximately two months in the hospital, receiving a high-protein and high-calorie diet, with significant nutritional recovery. Comments: Abuse by starvation, although rare, should always be considered of as one of the causes of child malnutrition and pediatrician should be aware of the child's development, as well as the family interactions, to prevent more severe nutritional and emotional consequences in the future.

  3. From Dominators to be Brothers: a dialogue of ecotheologie with J. Riechmann about the Animal Liberation

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    Afonso Tadeu Murad

    2016-12-01

    Full Text Available Jorge Riechmann is the author of extensive work devoted to philosophical reflection on ecology and sustainability. Among his significant works, we choose "Todos los animales somos hermanos" (2005. We will present an overview of the author's thinking about the relationship of humans with other animals, especially mammals. Riechmann addresses hot topics such as physio-biological-social continuous process of evolution and uniqueness of the human; the reasons to include the higher animals in the human moral community, and ethical and legal reasons of animal rights. It must be overcome speciesism, which considers only the animals as mere instruments. Although animals are not people, not moral agents, have intrinsic value. Because they feel pain and pleasure, and have a purpose for living, they deserve moral respect. They are "almost people" and have rights granted and recognized by humans. Next, we will do an exercise of ecotheology interlocution with Jorge Riechmann. We will take as reference the Encyclical Laudato Si and the work of Susin and Zampieri, Ethics and Theology of Animal Liberation.

  4. 'How we learned to kill our brother'?: memory, morality and reconciliation in Peru

    Directory of Open Access Journals (Sweden)

    2000-01-01

    Full Text Available “COMMENT AVONS-NOUS APPRIS A TUER NOS FRERES ?” : MEMOIRE, MORALE ET RECONCILIATION AU PEROU. Dans cet article nous nous demandons comment certains paysans d’Ayacucho (Pérou analysent à la fois la violence politique qui a façonné leur vie quotidienne depuis 1980 et l’ordre de tuer qui a pris forme dans le contexte du conflit armé entre Sentier Lumineux, les Forces Armées Péruviennes et les rondes paysannes. Depuis 1995, nous conduisons à cet effet une recherche anthropologique dans diverses communautés du département d’Ayacucho. Nous cherchons ici à voir comment le contexte de guerre structure la vie morale en défiant les règles élémentaires du comportement humain et le sens même de la vie en communauté. Nous avons recours à une approche généalogique pour analyser les origines des interprétations morales qui surgissent dans des contextes locaux spécifiques. Aussi bien dans le processus de militarisation et de démilitarisation de la vie quotidienne, les cadres moraux qui transparaissent à travers les récits des paysans s’avèrent être un mélange synchrétique de christianisme militant, de thèmes psycho-culturels et de l’appropriation de discours extra-locaux. “¿CÓMO APRENDIMOS A MATAR A NUESTROS HERMANOS?”: MEMORIA, MORALIDAD Y RECONCILIACIÓN EN EL PERÚ. En este artículo, exploramos cómo los campesinos en Ayacucho (Perú entienden tanto la violencia política que ha moldeado la vida cotidiana desde 1980, como el mandato de matar que surgió dentro del contexto del conflicto armado entre Sendero Luminoso, las Fuerzas Armadas Peruanas, y las rondas campesinas. Hemos estado llevando a cabo una investigación antropológica desde 1995 en varias comunidades en el departamento de Ayacucho. Pretendemos explorar cómo el contexto de guerra moldea la vida moral, desafiando concepciones de la conducta humana aceptable y el sentido mismo de vivir en una comunidad humana. Utilizamos un acercamiento genealógico para

  5. 'Brothers in arms'

    DEFF Research Database (Denmark)

    Adamsen, L; Rasmussen, J M; Pedersen, L S

    2001-01-01

    The study investigated how a group intervention programme (13 sessions over 16 weeks), designed for men with cancer (n = 17), affected their sense of well-being and had a positive impact on their ability to cope with the physical, psychological and social consequences of living with cancer...

  6. Gianco, my Brother

    Science.gov (United States)

    Rota, Ester Gasperoni

    As a child, Gianco (the nickname by which he was known to family and friends) wanted to be a cook. Since cooking has never been my "cup of tea" I gladly allowed him to experiment on a stove that had been given to me for Christmas, a little electric marvel equipped with a real oven. He concocted sauces, baked cookies and cakes, which were eminently edible. Perhaps thanks to his childhood practice, Gianco's cooking was always far better than mine.

  7. Mercury is Moon's brother

    International Nuclear Information System (INIS)

    Ksanfomalifi, L.V.

    1976-01-01

    The latest information on Mercury planet is presented obtained by studying the planet with the aid of radar and space vehicles. Rotation of Mercury about its axis has been discovered; within 2/3 of its year it executes a complete revolution about its axis. In images obtained by the ''Mariner-10'' Mercurys surface differs little from that of the Moon. The ''Mariner-10'' has also discovered the Mercurys atmosphere, which consists of extremely rarefied helium. The helium is continuously supplied to the planet by the solar wind. The Mercury's magnetic field has been discovered, whose strength is 35 x 10 -4 at the Equator and 70 x 10 -4 E at the poles. The inclination of the dipole axis to the Mercury's rotation axis is 7 deg

  8. Brothers Grimm. [Lesson Plan].

    Science.gov (United States)

    Discovery Communications, Inc., Bethesda, MD.

    Based on Grimm's fairy tales, this lesson plan presents activities designed to help students understand that fairy tales connect them to earlier generations, help them think about present situations, that magic figures prominently in fairy tales, and that fairy tales can inspire readers to create original works of art. The main activity in the…

  9. Big Brother Not Needed.

    Science.gov (United States)

    Heinen, Edward

    1983-01-01

    Cites the recent United States State Department's labeling of recent Canadian films--one on nuclear war and two on acid rain--as political propaganda as a sign of the need to review the nature of propaganda. Suggests that teaching students to intelligently evaluate propaganda is preferable to submitting to government dictum. (MM)

  10. Band of Brothers

    DEFF Research Database (Denmark)

    Pærregaard, Karsten

    2011-01-01

    Kapitlet diskuterer den rolle, som katolske broderskaber spiller i peruanske migranters religiøse praksis i USA, Spanien og andre lande. Den introducerer kort de katolske broderskabers historie i Spanien og det kolonial Latin Amerika og undersøger derpå det spirituelle slægtskab, som forbinder pe...

  11. Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    DEFF Research Database (Denmark)

    Vorwerk, P; Christoffersen, C T; Müller, J

    1999-01-01

    The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...... either of the two mutated receptors lacked basal or stimulated IR beta-subunit autophosphorylation. A third brother who inherited both normal alleles has an normal muscle phenotype and insulin sensitivity, suggesting a direct linkage of these IR mutations with the CFTDM phenotype....

  12. Síndrome de Waardenburg: achados audiológicos em 2 irmãos Waardenburg's syndrome: audiological findings in 2 brothers

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    Carlos Henrique F. Martins

    2003-01-01

    Full Text Available A síndrome de Waardenburg foi inicialmente descrita em 1951 por P.J. Waardenburg, como uma condição autossômica dominante que apresenta penetrância e expressividade variáveis de seus caracteres. Os sinais clínicos mais frequentes são: deslocamento lateral dos cantos internos dos olhos (telecanto, hiperplasia da porção medial dos supercílios (sinofris, base nasal proeminente e alargada, alterações na pigmentação da íris e da pele, surdez congênita, mecha branca frontal ou encanecimento precoce. Este estudo foi realizado em dois irmãos de uma família, que apresentavam características clínicas da síndrome de Waardenburg, entre elas a deficiência auditiva. Os pacientes foram submetidos à uma avaliação otorrinolaringológica, audiológica e genética.Waardenburg's Syndrome, first described in 1951 by P.J. Waardenburg, is an autossomal dominant condition with variable penetrance and expressivity of its features. The clinical signs are lateral displacement of the inner canthi of the eyes, confluent eyebrows, broad and prominent nasal root, pigmentation changes of the irises and skin, sensorineural deafness, white forelock or early graying of the hair. This study was based on two brothers who presented a typical clinical picture of Waardenburg's Syndrome, including hearing loss. Otolaryngological, audiological and genetical evaluations were conducted.

  13. Gregorio y Francisco Esparza: hermanos enfrentados ante la independencia de Texas, 1835-1836 Gregorio and Francisco Esparza: Brothers Who Fought Each Other During the Independence of Texas, 1835-1836

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    Gustavo Ernesto Emmerich

    2012-08-01

    Full Text Available En 1836 el ejército mexicano tomó el fuerte de El Álamo, en las afueras de San Antonio. Todos sus defensores, que combatían por la independencia de Texas, murieron en la acción, entre ellos Gregorio Esparza, un nativo de esa ciudad. Tras la batalla, su hermano Francisco, enrolado en el bando mexicano, le dio cristiana sepultura. Este artículo examina la saga de ambos hermanos virtualmente desconocida en México. La primera sección de este artículo contextualiza la independencia de Texas, la segunda contiene resultados de investigación documental realizada por el autor sobre Gregorio y Francisco Esparza. La tercera comenta una entrevista realizada a un hijo de Gregorio sobre los papeles de su padre y su tío en El Álamo. La cuarta evalúa críticamente las evidencias. La quinta ofrece una reflexión sobre los motivos que habrían llevado a los hermanos Esparza -y en general a la comunidad texana de origen mexicano- a enfrentarse respecto a la independencia de Texas y, finalmente, en los anexos se transcriben los registros parroquiales y censales de la época y se extractan y comentan diversos relatos del hijo de Gregorio y de otros descendientes.In 1836, the Mexican army captured Fort Alamo outside San Antonio. All its defenders, who were fighting for the independence of Texas, died in action. Among these was Gregorio Esparza, a native of that city. After this battle, his brother Francisco, enlisted in the Mexican army, gave him a Christian burial. This article examines the saga of the two brothers, virtually unknown in Mexico. The first section contextualizes the independence of Texas. The second contains the results of the author's documentary research on Gregorio and Francisco Esparza. The third comments on an interview with one of Gregorio's sons on the roles played by his father and uncle at The Alamo. The fourth critically evaluates the evidence. The fifth provides a reflection on the reasons that led the Esparza brothers -and the

  14. Experiência do irmão sadio em relação à doença e hospitalização do irmão com câncer Experiencia del hermano saludable en relación a la enfermedad y hospitalización del hermano concáncer Experience of a healthy brother in relation to the disease and hospitalization of his brother with cancer

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    Maria de Fátima de Lima Cheron

    2011-01-01

    Full Text Available OBJETIVO: Compreender o significado da experiência de ter um irmão com câncer na perspectiva do irmão sadio. MÉTODOS: Pesquisa descritiva de abordagem qualitativa. Foram realizadas entrevistas semiestruturadas com cinco irmãos de crianças com câncer assistidas em instituição filantrópica localizada no Município de São Paulo. RESULTADOS: O tema central tornando-se amadurecido com o sofrimento permitiu revelar que o irmão sadio torna-se amadurecido em razão do sofrimento que lhe é imposto no decorrer dos acontecimentos. Passa a valorizar a convivência familiar e os pequenos atos do cotidiano que lhe eram despercebidos. CONCLUSÃO: A equipe de saúde precisa reconhecer a experiência do irmão e incluí-lo no cuidado prestado em todas as fases da doença.OBJETIVO: Comprender el significado de la experiencia de tener un hermano con cáncer en la perspectiva del hermano saludable. MÉTODOS: Investigación descriptiva de abordaje cualitativo. Fueron realizadas entrevistas semiestructuradas con cinco hermanos de niños con cáncer asistidos en una institución filantrópica localizada en el Municipio de Sao Paulo. RESULTADOS: El tema central tornándose maduro con el sufrimiento permitió revelar que el hermano saludable madura en razón del sufrimiento que le es impuesto en el transcurso de los acontecimientos. Pasa a valorizar la convivencia familiar y los pequeños actos del cotidiano que le eran desapercibidos. CONCLUSIÓN: El equipo de salud necesita reconocer la experiencia del hermano e incluirlo en el cuidado prestado en todas las fases de la enfermedad.OBJECTIVE: To understand the meaning of the experience of having a sibling with cancer from the perspective of healthy brother. METHODS: A descriptive qualitative research approach. Semi-structured interviews were conducted with five siblings of children with cancer who were receiving care in a philanthropic institution located in São Paulo. RESULTS: The central theme that

  15. Cross-cousin marriage among the Yanomamö shows evidence of parent-offspring conflict and mate competition between brothers.

    Science.gov (United States)

    Chagnon, Napoleon A; Lynch, Robert F; Shenk, Mary K; Hames, Raymond; Flinn, Mark V

    2017-03-28

    Marriage in many traditional societies often concerns the institutionalized exchange of reproductive partners among groups of kin. Such exchanges most often involve cross-cousins-marriage with the child of a parent's opposite-sex sibling-but it is unclear who benefits from these exchanges. Here we analyze the fitness consequences of marrying relatives among the Yanomamö from the Amazon. When individuals marry close kin, we find that ( i ) both husbands and wives have slightly lower fertility; ( ii ) offspring suffer from inbreeding depression; ( iii ) parents have more grandchildren; and ( iv ) siblings, especially brothers, benefit when their opposite-sex siblings marry relatives but not when their same-sex siblings do. Therefore, individuals seem to benefit when their children or opposite-sex siblings marry relatives but suffer costs when they, their parents, or same-sex siblings do. These asymmetric fitness outcomes suggest conflicts between parents and offspring and among siblings over optimal mating strategies. Parental control of marriages is reinforced by cultural norms prescribing cross-cousin marriage. We posit that local mate competition combined with parental control over marriages may escalate conflict between same-sex siblings who compete over mates, while simultaneously forging alliances between opposite-sex siblings. If these relationships are carried forward to subsequent generations, they may drive bilateral cross-cousin marriage rules. This study provides insights into the evolutionary importance of how kinship and reciprocity underlie conflicts over who controls mate choice and the origins of cross-cousin marriage prescriptions.

  16. Neonatal hyperthyroidism: neonatal clinical course of two brothers born to a mother with Graves-Basedow disease, before and after total thyroidectomy.

    Science.gov (United States)

    Zuppa, A A; Sindico, P; Savarese, I; D'Andrea, V; Fracchiolla, A; Cota, F; Romagnoli, C

    2007-04-01

    About 1-2% of infants born to mothers with Graves' disease or Hashimoto's thyroiditis develop neonatal hyperthyroidism because of transplacental passage of IgG stimulating TSH receptors (TRAb). To evaluate the effect of maternal total thyroidectomy on neonatal clinical course. We describe two brothers born to a mother with Graves' disease, before and after total thyroidectomy. The first child showed persistent tachycardia, the presence of TRAb and a laboratory pattern of hyperthyroidism. Lugol's solution was started and then propylthiouracil was added. Digitalis, furosemide and diazepam were necessary for treatment of heart failure, hypertension and irritability. On the 70th day of life, hormone serum levels normalized and treatment was interrupted. TRAb normalized by the third month of life. The second infant was born 2 years after the mother underwent total thyroidectomy. In spite of a laboratory pattern of hyperthyroidism and positivity to TRAb, he showed only considerable weight loss, and no therapy was required. TRAb may persist after total thyroidectomy: clinical and instrumental follow-up of the newborn is recommended.

  17. Duas variantes da representação do real na cultura midiática: o exorbitante Big Brother brasil e o circunspeto Edifício Master

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    Fernando Andacht

    2005-06-01

    Full Text Available The text aims at describing a remarkable phenomenon in our present day media culture: the representation of the real in television and cinema. Through the comparison between two audiovisual genres which deal with the real in the media, the Edificio Master documentary, directed by Eduardo Coutinho, and the Big Brother Brasil television program, the aim is to understand the cultural signification of two very different esthetic products that, nevertheless, share the dominant use of indexical signs, as their specific strategy. Without trying to minimize the obvious esthetic and ethic differences that exist between the reality show of the multinational company Endemol and the highly acclaimed Brazilian film, the article considers a fundamental tendency in present day media culture, namely, the techological and artistic production of an illusory intimacy at a distance, as a way of reflecting on identity. The functioning of the reality show aims at wrenching out of its orbit the normality of its participants, who must dwell in an abnormal place; the documentary, on the other hand, aims at offering a circumspect and moral vision of our everyday world, there where life takes place.

  18. The Brothers Grimm in The Library of the National Museum of Slovenia: the Legacy of Anastazij Grün

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    Urška Pajk

    2013-11-01

    Full Text Available ABSTRACTThe article is focused on the “treasures” of the National Museum of Slovenia Library a part of them being the books of the count Anton Alexander Auersprg writing under the pseudonym of Anastazij Grün. In 1910 his legacy was included into the museum’s book collection. The poet Anastazij Zelenc was an interesting and unique historical personage and a passionate collector of books and other printed materials. He became especially enthusiastic about antique history and folk literature. Thus, it is not surprising to find the Grimm’s literary “production” in his collection. Anastazij Grün is not sufficiently known in Slovenia. Therefore it is convenient to underline his importance at the occasion of the 150th anniversary of the death of the great fairy tale writer, ethnologist and philologist Jacob Grimm (20th September 2013.

  19. Brothers in arms or peace? The media representation of Swedish and Norwegian defence- and military co-operation

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    Stig Arne Nohrstedt

    2010-10-01

    Full Text Available This article discusses the relevance of Johan Galtung's model for peace journalism and critical discourse analysis (CDA in light of the media coverage of Swedish and Norwegian defence cooperation. By analysing the proposal for closer military cooperation between the Nato-member Norway and the non-aligned Sweden the article emphasises the paradox that the fact that both Sweden and Norway have forces fighting in Afghanistan was not mentioned when the heads of the Norwegian and Swedish Defence in a joint article justified the need for a closer cooperation between the two countries. Thus this analysis illustrates some limitations of the peace journalism perspective and the necessity to take a contextual approach in which also the possibility of "peace talk" being part of a war discourse is considered.

  20. Sibling Death after Being Thrown from Window by Brother with Autism: Defenestration, an Emerging High-Risk Behavior

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    Osman Sabuncuoglu

    2015-01-01

    Full Text Available Children diagnosed with autistic spectrum disorders (ASD may have serious behavioral problems such as aggression, self-injury, and violence. However, the literature on ASD either overrules any correlation between aggression and ASD or maintains the fact that the efforts to link them have so far been inconclusive. Although severe forms of violence are extremely rare in children with autism, there are a few cases reported in the literature with significant harm to siblings. We hereby report an 8-year-old boy with ASD who caused the death of his sibling by throwing her out of the window. Shared similarities of all defenestration cases indicate a pattern of high-risk behavior threatening the survival of minors. We recommend precautions against this high-risk behavior in children with ASD.

  1. BIG BROTHER IS WATCHING YOU! TO BE OR NOT TO BE ONLINE... OR SCREEN AS OUR OWN TECHNOLOGICAL ADDRESS

    Directory of Open Access Journals (Sweden)

    Vanda Maria Sousa

    2014-12-01

    Full Text Available This article seeks to answer the question: how the screens are interposed between the subject and reality, in contexts of the New Technologies of Information and Communication, particularly in the case of television screens (in the reality show format and computer screens (by the profusion of social networks? Using the interpretative methodology, our goal is to take as a starting point the etymology of technic and technology to establish the technological nature of man’s relationship with reality. Once this premise is demonstrated, we will convene the Heideggerian concepts (dasein and ge-stell to interpret how the technology of the screen meets a social need for happiness that comes from the media in a world that re-discovers itself as iconic. Each of us is called upon, in our day-to-day life, to an important, special and urgent meeting with the representation of our own selves, against a screen, where will be its own place of happiness. We intend to assess whether ideologies are hiper-evaluated today, especially when translating reality into binary conceptions of the world, projecting dasein on the demand for unity (1, opposing it to failure (0, each time using the screen more like a mirror or a window, and forgetting its function as a ge-stell by making it a promotion, and not doing it as a way to discover dasein, but, instead, as the opening of the simulacra itself.

  2. Separating Sisters From Brothers: Ethnic Relations and Identity Politics in the Context of Indigenous Land Titling in Indonesia

    Directory of Open Access Journals (Sweden)

    Stefanie Steinebach

    2017-06-01

    Full Text Available Environmental and social transformations in Jambi province, Indonesia, are inextricably interlinked. Large-scale agro-industrial development and nature conservation policies equally alienate local communities from their agricultural lands and turn land into a scarce resource. Consequently, access to agricultural land becomes increasingly contested, not only between communities and state institutions or companies but also among communities themselves. To secure or restore local ‘indigenous’ land rights against land grabbing and green grabbing by states and companies, indigenous land titling has become a powerful tool all over the world. Ongoing activities of indigenous land titling in Indonesia have been largely perceived as an act of justice by indigenous and land rights activists and affected communities. Yet, a challenging step towards titling is the identification of who is and who is not ‘indigenous’. This highly political process creates ethnicity-based identities tied to rights and possibilities around land as a contested resource. Based on a case study of a national park in central Jambi, this paper shows that what is perceived as an act of justice against the state can also produce injustice among local communities by heavily impacting and transforming local social structures and relations.

  3. Who is my brother's keeper?

    Science.gov (United States)

    Kottow, M H

    2002-02-01

    Clinical and research practices designed by developed countries are often implemented in host nations of the Third World. In recent years, a number of papers have presented a diversity of arguments to justify these practices which include the defence of research with placebos even though best proven treatments exist; the distribution of drugs unapproved in their country of origin; withholding of existing therapy in order to observe the natural course of infection and disease; redefinition of equipoise to a more bland version, and denial of post-trial benefits to research subjects. These practices have all been prohibited in developed, sponsoring countries, even though they invariably have pockets of poverty where conditions comparable to the Third World prevail. Furthermore, the latest update of the Declaration of Helsinki clearly decries double ethical standards in research protocols. Under these circumstances, it does not seem appropriate that First World scholars should propose and defend research and clinical practices with less stringent ethical standards than those mandatory in their own countries. Recent years have witnessed frequent reports of less stringent ethical standards being applied to both clinical and research medical practices, for the most part in the field of drug trials and drug marketing, initiated by developed countries in poorer nations. Still more unsettling, a number of articles have endorsed the policy of employing ethical norms in these host countries, which would be unacceptable to both the legislations and the moral standards of the sponsor nations. Also, these reformulations often contravene the Declaration of Helsinki or one of its updates. This paper is not so much concerned with the actual practices, which have been subjected to frequent scrutiny and publicly decried when gross misconduct occurred. Rather, my concern relates to the approval and support such practices have found in the literature on bioethics from authors who might be expected to use their energy and scholarship to explore and endorse the universalisability of ethics rather than to develop ad hoc arguments that would allow exceptions and variations from accepted moral standards. To this purpose, issue will be taken with arguments in three fields: medical and pharmaceutical practices, research strategies, and local application of research results.

  4. Novel about Artist: Postmodern Variations (Instantiated by Novels “The Tin Drum” by Günter Grass, “Brother of Sleep” by Robert Schneider, “Perfume: The Story of a Murderer” by Patrick Süskind

    Directory of Open Access Journals (Sweden)

    Sofiya Varetska

    2013-12-01

    Full Text Available An attempt to show the modification of classic novel about an artist (Künstlerroman through a prism of postmodernism instantiated by German novels of the second half of the twentieth century “The Tin Drum”, “Brother of Sleep”, “Perfume: The Story of a Murderer” was accomplished. Crisis of artistic apperception in the twentieth century is demonstrated. Different conceptions of the creative process of main characters are compared. The main attention was focused on the clash between man and artist, life and art, daily routine and spirituality. In the postmodern age the cynical worldview model is predominating. At the same time tales, where magic and reality, sentimentality and brutality are combined, enjoy widespread popularity. An art of genius has positive connotations in general, but some of chosen novels are revealing the reverse side of the coin, when the art is capable to create an evil in its superior manifestations. For a wonder a presence of negative, monstrosity and disgust attract attention of the crowd rather than beauty. Therefore tin the article new idea that talent is on the verge of monstrosity is asserted. These two concepts exist together rely on each other. Every hero is like two-faced Janus to some extent. On the one hand, being endowed with Divine Grace he has a talent, but on the other hand, having something demoniacal is possessed by physical defect. On the one hand, they limelight and fire our imagination by their unusualness, on the other hand, they push away by their monstrosity and disgust. Main characters are always teetering on the edge. However the notion of edge is taking the wider meaning in the contemporary society. Consequently, having used all features of classic novel about an artist and portrayed them through a prism of modern perception of the world, writers created a new compilation – postmodern novel about an artist.

  5. Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    DEFF Research Database (Denmark)

    Vorwerk, P; Christoffersen, C T; Müller, J

    1999-01-01

    to be compound heterozygotes for mutations in the IR gene. The maternal allele was alternatively spliced in exon 17 due to a point mutation in the -1 donor splice site of the exon. The abnormal skipping of exon 17 shifts the amino acid reading frame and leads to a truncated IR, missing the entire tyrosine kinase......The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...... domain. In the correct spliced variant, the point mutation is silent and results in a normally translated IR. The paternal allele carries a missense mutation in the tyrosine kinase domain. All three cDNA variants were present in the lymphocytes of the patients. Purified IR from 293 cells overexpressing...

  6. Realidade e ficção no Big Brother e no CQC: a promessa de transparência hiper-realista versus o encobrimento irônico e sedutor do real

    OpenAIRE

    Polydoro, Felipe

    2010-01-01

    A realidade tornou-se tema central de uma série de produtos midiáticos contemporâneos. Em variados meios (cinema, televisão, literatura, mídia impressa), alastram-se objetos que exploram a fronteira entre o real e a ficção e que atendem a um anseio por signos da realidade vivida. Neste trabalho, analisamos dois programas de televisão que refletem o fenômeno citado: o humorístico Custe o Que Custar (CQC) e o reality show Big Brother Brasil. A base para esta análise é a teoria de Jean Baudrilla...

  7. “‘Need a Minister? How About Your Brother?’: The Universal Life Church between Religion and Non-Religion”

    Directory of Open Access Journals (Sweden)

    Dusty Hoesly

    2015-10-01

    Full Text Available National media outlets have observed that weddings in the United States, especially for young educated people, are increasingly performed by ministers who are friends or relatives of the couple and who become ordained online just for that purpose. The primary organization licensing these ministers, and thus authorizing these weddings as legally valid, is the Universal Life Church (ULC, which has ordained over 20 million people since 1962. To date, there has been no focused study of the ULC or lifecycle rituals conducted under its auspices. According to my original survey, interview, and participant observation data, both ULC ministers and the couples who engage them typically self-describe as non-religious, usually as spiritual, seekers, humanist, or generically “not religious.” Similarly, they describe their weddings in “non-religious” terms, emphasizing the personalization of the ceremony to match their particular beliefs and tastes as well as the conscious exclusion of most “religious” language. These “secular” or “spiritual” wedding ceremonies reveal non-religious couples’ desires for an alternative apart from bureaucratic civil ceremonies or traditional religious rites. This article explains why “secular” people select ULC ministers for their weddings, how ULC ministers see themselves as “non-religious” while being members of a legally-recognized religion, and how ULC ministers and couples married by them label and valuate their “non-religious,” personalized wedding ceremonies. My examination of ULC membership and weddings reveals not only the diversity of non-theistic self-identification and lifecycle ritualization, but also how constructs such as “religious” and “secular” can be co-constitutive rather than purely oppositional.

  8. Desempenho psicolinguístico e escolar de irmãos com mielomeningocele Psycholinguistic and school performance of brothers with myelomeningocele

    Directory of Open Access Journals (Sweden)

    Dionísia Aparecida Cusin Lamônica

    2012-08-01

    Full Text Available TEMA: mielomeningocele e consequências para o desenvolvimento de habilidades psicolinguísticas e escolares. PROCEDIMENTOS: o objetivo deste estudo foi descrever e refletir sobre o desempenho psicolinguístico e escolar de irmãos com mielomeningocele lombar baixa. Participaram do estudo um menino de 14 anos e 5 meses (P1 e sua irmã de 6 anos e 6 meses (P2. Os procedimentos constaram de entrevista com familiares, Observação do Comportamento Comunicativo (OCC, Teste de Vocabulário por Imagens Peabody - TVIP, Teste Illinóis de Habilidades Psicolinguísticas (ITPA, Perfil de Habilidades Fonológicas (PHF, Teste de Desempenho Escolar (TDE, e Reconhecimento de letras e números (RLN. A análise dos resultados foi descritiva respeitando os manuais dos instrumentos. RESULTADOS: a linguagem oral encontra-se sem alteração evidente. No ITPA e PHF, verificou-se que P1 e P2 apresentaram dificuldade nas habilidades de memória, closura auditiva, expressão verbal, combinação de sons e consciência fonológica. P1 ainda apresentou dificuldade na habilidade de recepção visual e P2 nas habilidades de associação auditiva e closura gramatical. Ambas as crianças apresentaram alteração nas atividades de aprendizagem. CONCLUSÃO: os participantes do estudo apresentaram comportamento comunicativo, habilidades de linguagem oral e vocabulário receptivo sem alterações evidentes. P1 e P2 apresentaram alterações nas habilidades psicolinguísticas bem como no desempenho de atividades envolvendo leitura, escrita e aritmética. As dificuldades apresentadas causam impacto importante nas atividades acadêmicas, demonstrando vulnerabilidade cerebral no sistema de suporte para atividade de aprendizagem.BACKGROUND: meningomyelocele and consequences on the development of psycholinguistic and school abilities. PROCEDURES: the purpose of this study was to describe and reflect on the psycholinguistic and school performance of siblings with low lumbar

  9. 77 FR 75503 - Wright Brothers Day, 2012

    Science.gov (United States)

    2012-12-20

    ... Wright pursued their lifelong dream. Like so many Americans before and after them, these two men achieved... stay ahead of the curve and keep America moving forward. With their game-changing feat, the Wright...

  10. Unequal brothers : are homeopathy and hormesis linked?

    Science.gov (United States)

    Oberbaum, Menachem; Frass, Michael; Gropp, Cornelius

    2015-04-01

    The debate between those who believe homeopathy and hormesis derive from the same root and those who believe the two are different phenomena is as old as hormesis. It is an emotionally loaded discussion, with both sides fielding arguments which are far from scientific. Careful analysis of the basic paradigms of the two systems questions the claim of the homeopaths, who find similarities between them. The authors discuss these paradigms, indicating the differences between the claims of homeopathy and hormesis. It is time for thorough and serious research to lay this question to rest. One possible approach is to compare the activity of a hormetic agent, prepared in the usual way, with that of the same agent in the same concentration prepared homeopathically by serial dilution and succussion. Copyright © 2015. Published by Elsevier Ltd.

  11. HALF-BROTHERS IN THE SCHULHOF FAMILY?

    International Nuclear Information System (INIS)

    Vokrouhlicky, David; Nesvorny, David

    2011-01-01

    Disruptive collisions in the asteroid belt produced groups of fragments known as the asteroid families. The studies of identified asteroid families help us to better understand issues related to impact physics, space weathering, asteroid interior, and collisional evolution of the main belt. Here, we analyze a family near the central main belt asteroid (2384) Schulhof. We show that the previously found group of objects around (81337) 2000 GP36 is actually a sub-cluster in the larger Schulhof family. Using backward integrations we demonstrate that the orbits of sub-cluster asteroids converge to that of (2384) Schulhof at 780 ± 100 kyr ago, suggesting that the breakup event happened very recently. Interestingly, a similar analysis of the two newly discovered members of the Schulhof family may indicate a second event ∼< 100 kyr ago (e.g., secondary collision, fission, satellite instability). If confirmed, the formation history of the Schulhof family would suggest that small asteroids may have very colorful lifetimes. Additional astrometric observations of the two new member asteroids will be needed to improve their present orbit and better constrain their past histories.

  12. The 16th International Twin Congress: Highlights from Madrid/Twin Research: Twin Study of Partner Aggression; ABO Incompatibility in Dizygotic Twins; Growth Discordance in a Monoamniotic Twin Pair; Quick Note on Twin Implantation/In the Media: Long-Lost Twins Found; NASA Twin Experiment; Twin Brothers and the Las Vegas Attack; Retired Twin Airline Pilots; Twin Film Clips.

    Science.gov (United States)

    Segal, Nancy L

    2018-02-01

    Highlights from the 16th International Twin Congress, held in Madrid, Spain from November 16-18, 2017, are presented. The Twin Congress, formerly held every three years, now takes place biennially with a single-day meeting organized during the off years. This meeting is the largest gathering of scientific twin researchers, medical personnel, and representatives of multiple birth organizations in the world. This overview is followed by reviews of recent twin research and commentary concerning partner aggression, ABO incompatibility in dizygotic twins, growth discordance in a monoamniotic twin pair and twin implantation. The article closes with summaries of timely topics in the media, namely a father's finding of his long-lost twin children, early results from the NASA twin experiment, twin brothers at the center of the October 2017 Las Vegas attack, retired twin airline pilots, and clips from recent films with twin-based themes.

  13. قاعـدة "الفنـاء في الإخـوان" في فكر بديـع الزمـان - Dr. Farhad Ibrahim Akbar al-Shawani: The rule of self forgetfulness for the sake of brothers according to the thought of Bediuzzaman

    OpenAIRE

    الشواني, د. فرهاد إبراهيم أكبر

    2015-01-01

    قاعـدة قاعـدة "الفنـاء في الإخـوان" في فكر بديـع الزمـان-دراسة تأصيلية مقاصدية للوحدة الإسلامية- -ABSTRACT- The rule of self forgetfulness for the sake of brothers according to the thought of Bediuzzaman Dr. Farhad Ibrahim Akbar al-Shawani This study explores an important rule which was linked to its sources from the spirit of the holy Quran and the prophetic tradition by Ustadh Nursi. It states that a person should experience self forgetfulness for the sake of his community. An ind...

  14. A biographical portrait of two sculptors in the shadows: the brothers Miguel Jerónimo and Jerónimo Francisco García (1576-1639/1644

    Directory of Open Access Journals (Sweden)

    Manuel García Luque

    2017-12-01

    Full Text Available This paper offers a first biographical note on the 17th-century sculptors of Granada Miguel Jerónimo and Jerónimo Francisco García, through the use of previously unpublished documents such as their baptismal and death certificates or the will of Miguel. Furthermore, the author presents unknown information and pieces that help to understand more clearly their work in terracotta, fundamental in the transition from Mannerism toward Naturalism in Andalusian sculpture.

  15. O imigrante e seus irmãos: as pesquisas empíricas de Florestan Fernandes e Gino Germani The immigrant and his brothers: the empirical researches of Florestan Fernandes and Gino Germani

    Directory of Open Access Journals (Sweden)

    Antonio Brasil Jr.

    2010-01-01

    Full Text Available No trabalho, destaco, em perspectiva comparada, algumas formulações de Florestan Fernandes e de Gino Germani, protagonistas da renovação da sociologia nas universidades de São Paulo e de Buenos Aires, respectivamente. Através de pesquisas empíricas, os dois procuraram investigar em que sentido a modernização afetava diferencialmente os grupos sociais, repondo padrões seculares de desigualdade. Fernandes e Germani viram, ainda, no "imigrante de ultramar", o portador por excelência das mudanças em curso, porquanto teria logrado se inserir, tanto em São Paulo quanto em Buenos Aires, nas posições mais dinâmicas da ordem capitalista em expansão, apesar de seu baixo impacto na democratização do sistema de dominação nos dois contextos.In the paper, I compare some arguments about the social change developed by Florestan Fernandes and Gino Germani, protagonists of the renewal of sociology at the universities of Sao Paulo and Buenos Aires, respectively. Through empirical research, both sought to investigate how the modernization process differentially affected social groups, restoring durable patterns of inequality. Fernandes and Germani considered, moreover, the "immigrant" the main agent of the social changes underway, due to his successful insertion, in Sao Paulo and Buenos Aires, in the most dynamic positions of the capitalist order in expansion, despite his low impact on the democratization of the system of domination in both contexts.

  16. Big brothers and little sisters? Sex selection and birth order.

    Science.gov (United States)

    Salmon, Catherine

    2007-09-01

    Should you be allowed to choose the sex of your child? Even before the advent of modern reproductive technologies, people have expressed interest in producing a child of a specific sex, trying everything from herbal treatments to sexual positions that have been claimed to produce a male or female child. Modern technologies such as flow cytometry make this a realistic possibility but what might the consequences be? In India and China, a preference for male offspring has led (via abortion) to a significant sex-ratio imbalance in those populations. Do other countries express strong preferences for male or female offspring? This article will address the possible birth order implications. Will we live in a world of first-born boys and second-born girls?

  17. Brothers at War? Reflections on an Internecine Conflict between ...

    African Journals Online (AJOL)

    1999-01-08

    Jan 8, 1999 ... by civil wars, inter-state wars, conventional wars and ethnic conflicts. ... Over the past three decades, the political conflicts in Africa resulted in humanitarian crises and ... management roles to regional and sub-regional organisations. ... the origins of this conflict, to be immediately followed by an analysis of ...

  18. French physicist's brother denies links to Al Qaeda

    CERN Multimedia

    Overbye, Dennis

    2009-01-01

    "Days after the French authorities placed a physicist working in Switzerland under formal investigation in a terror case, a portrait of the man and his work has begun to emerge from interviews with officials and his lawyer"

  19. The three good brothers charm : some historical points / Lea Olsan

    Index Scriptorium Estoniae

    Olsan, Lea T.

    2011-01-01

    Ravimise loitsudest: keskajal levinud legendaarsest kolme venna (tres boni fratres - lad. k.) loitsust haava parandamiseks; ettekanne rahvusvahelisel konverentsil "Charms, charmers and charming" Bukarestis 2010. a.

  20. Nuns, Brothers, and the Religion and Stress Questionnaire.

    Science.gov (United States)

    Rayburn, Carole A.; And Others

    Women have been entering into religious leadership positions in larger numbers, although the field is still male-dominated. Stress and strain of both men and women in the field of religion has been experienced from the impact of such change. In this study, Roman Catholic nuns, who have not been seen by their own church as clerical workers or even…

  1. Brothers Grimm Bicentenntial: Blueprint for a Community Celebration.

    Science.gov (United States)

    Novak, Sigrid Scholtz

    Faculty at McNeese State University (Louisiana) and local civic, educational, and cultural groups encouraged their community to commemorate the anniversary of the births of Jacob and Wilhelm Grimm, German scholars who recorded fairy tales, myths, legends, and folk songs that are now an important part of the western world's cultural heritage,…

  2. Tutankhamun and his brothers. Familial gynecomastia in the Eighteenth Dynasty.

    Science.gov (United States)

    Paulshock, B Z

    1980-07-11

    Many images of the last four hereditary pharaohs of the Eighteenth Egyptian Dynasty (1559 BC to 1319 BC), Amenophis III, Amenophis IV (also known as Akhenaten), Smenkhkare, and Tutankhamun, show them with gynecomastia. Amenophis III was most probably the sire of the last three. The feminine physique and other abnormalities of Amenophis IV have been extensively commented on as indicative of some sort of pathological condition, but the gynecomastia of the others, including Tutankhamun, has been glossed over or considered an artistic mannerism of the El Amarna period. An alternative theory, that the gynecomastia was actually representational and indicative of a familial abnormality in two or three generations, is suggested.

  3. Babbitt's Brothers & Sisters: Raising Ethical Issues in Business Literature.

    Science.gov (United States)

    Halpern, Jeanne W.

    A college-level course in business literature is an ideal place to raise and discuss ethical issues. To be successful, a teacher of this course must engage student interest, help the students articulate and understand their own ethical attitudes, clarify the stance and artistry of the author, and refine student responses to ethical questions. When…

  4. Our Brother's Keeper: The Indian in White America.

    Science.gov (United States)

    Cahn, Edgar S., Ed.; Hearne, David W., Ed.

    The text describes the American Indian's frustrations with his closed world, which thwarts and penalizes individual and tribal self-realization, which rewards and perpetrates dependency, and which demands alienation from one's heritage as a price for survival. American society is described as arrogant and as attempting to insure that by systematic…

  5. Big brother is watching you: eavesdropping to resolve family conflicts

    OpenAIRE

    Dreiss, A.N.; Ruppli, C.A.; Faller, C.; Roulin, A.

    2013-01-01

    Adult animals can eavesdrop on behavioral interactions between potential opponents to assess their competitive ability and motivation to contest resources without interacting directly with them. Surprisingly, eavesdropping is not yet considered as an important factor used to resolve conflicts between family members. In this study, we show that nestling barn owls (Tyto alba) competing for food eavesdrop on nestmates’ vocal interactions to assess the dominance status and food needs of opponents...

  6. Big Brother Is Watching: Video Surveillance on Buses

    Science.gov (United States)

    Sloggett, Joel

    2009-01-01

    Many school districts in North America have adopted policies to permit cameras on their properties and, when needed, on buses used to transport students. With regard to school buses, the camera is typically a tool for gathering information to monitor behavior or to help investigate a complaint about behavior. If a picture is worth a thousand…

  7. Schooling for Humanity: When Big Brother Isn't Watching.

    Science.gov (United States)

    Solmitz, David O.

    Most educational reform initiatives of the past 20 years are geared towards ensuring that the United States dominates the emerging global economy. What is lost in this rush to the top of the materialist heap is an education for the more enduring human values: creativity, intellectual development, care, social justice, and democracy. In this book,…

  8. Telemonitoring in heart failure: Big Brother watching over you.

    Science.gov (United States)

    Dierckx, R; Pellicori, P; Cleland, J G F; Clark, A L

    2015-01-01

    Heart failure (HF) is a leading cause of hospitalisations in older people. Several strategies, supported by novel technologies, are now available to monitor patients' health from a distance. Although studies have suggested that remote monitoring may reduce HF hospitalisations and mortality, the study of different patient populations, the use of different monitoring technologies and the use of different endpoints limit the generalisability of the results of the clinical trials reported, so far. In this review, we discuss the existing home monitoring modalities, relevant trials and focus on future directions for telemonitoring.

  9. Familial Churg-Strauss Syndrome in a Sister and Brother.

    Science.gov (United States)

    Alyasin, Soheyla; Khoshkhui, Maryam; Amin, Reza

    2015-06-01

    Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis. It is characterized by asthma, allergic granulomatosis and vasculitis. This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid. In every asthmatic patient with prolonged fever, eosinophilia and multisystemic involvment, CSS should be considered.

  10. Vennalik maja = A Brotherly House / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2002-01-01

    2001. a. Tallinnas Pirita teel valminud eramu projekteeris Arhitektibüroo Emil Urbel. Arhitektid Emil Urbel ja Indrek Erm, sisearhitekt Taso Mähar. Konstruktsioonid: E-Inseneribüroo. 5 ill.: korruste plaanid, sisevaade, välisvaated

  11. Hereditary Gigantism-the biblical giant Goliath and his brothers.

    Science.gov (United States)

    Donnelly, Deirdre E; Morrison, Patrick J

    2014-05-01

    The biblical giant Goliath has an identifiable family tree suggestive of autosomal dominant inheritance. We suggest that he had a hereditary pituitary disorder possibly due to the AIP gene, causing early onset and familial acromegaly or gigantism. We comment on the evidence within the scriptures for his other relatives including a relative with six digits and speculate on possible causes of the six digits. Recognition of a hereditary pituitary disorder in the biblical Goliath and his family sheds additional information on his and other family members' battles with David and his relatives.

  12. Examining Big Brother's Purpose for Using Electronic Performance Monitoring

    Science.gov (United States)

    Bartels, Lynn K.; Nordstrom, Cynthia R.

    2012-01-01

    We examined whether the reason offered for electronic performance monitoring (EPM) influenced participants' performance, stress, motivation, and satisfaction. Participants performed a data-entry task in one of five experimental conditions. In one condition, participants were not electronically monitored. In the remaining conditions, participants…

  13. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Flory, David

    2015-09-01

    This review of the governance of maternity services at South Tipperary General Hospital has focussed on the systems and processes for assurance of service quality, risk management and patient safety primarily inside the hospital but also in the Hospital Group structure within which it operates. The effectiveness of the governance arrangements is largely determined by the quality of the leadership and management – both clinical and general – which designs, implements, and oversees those systems and processes and is ultimately responsible and accountable.\\r\

  14. Stepping into the dark: mourning in Astrid Lindgren’s The brothers Lionheart1

    OpenAIRE

    Richards, Alan

    2011-01-01

    Astrid Lindgren’s juvenile novel, Bröderna Lejonhjärta (1973), has enchanted me since I first read it while studying at the University of Alberta. In part, I write this essay to uncover why this story haunts me. More importantly, however, I wonder what young readers of the twenty-first century in Canada, where I live, and in North America generally, might make of this modern fairy tale and its parallel worlds of Lindgren’s childhood Sweden and an imaginary realm of adventure, Nangiyala. How m...

  15. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Longford

    LENUS (Irish Health Repository)

    O'Shea, Dr Eamon

    2005-01-01

    This report presents both the proceedings of the Council’s conference, Planning for an Ageing Population: Strategic Considerations, and the Council’s discussion paper, ‘The Older Population: Information Issues and Deficits’, which was introduced at that conference.\\r\

  16. Brothers or Rivals? Iran and the Shi'a of Iraq

    National Research Council Canada - National Science Library

    Hunter, Robert C

    2006-01-01

    This thesis examines the loyalty of the Shi a of Iraq. While some Sunni Arab leaders have recently accused the Shi a of Iraq of pledging loyalty to Iran, in fact the Iraqi Shi a are loyal to their own nation...

  17. "[This] Book of Odd Tales/Which Transform the Brothers Grimm": Teaching Anne Sexton's "Transformations"

    Science.gov (United States)

    Keely, Karen A.

    2008-01-01

    Folklorist Andrew Lang, in his Preface to his 1910 edited collection "The Lilac Fairy Book", celebrates the ongoing repetition and retelling of fairy tales, including both the cozy retelling by the family fireplace. In the century since Lang wrote these words, many authors have joined the ranks of Shakespeare and Homer in putting fairy tale…

  18. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Davoren, Mary

    2015-01-01

    Patients admitted to a secure forensic hospital are at risk of a long hospital stay. Forensic hospital beds are a scarce and expensive resource and ability to identify the factors predicting length of stay at time of admission would be beneficial. The DUNDRUM-1 triage security scale and DUNDRUM-2 triage urgency scale are designed to assess need for therapeutic security and urgency of that need while the HCR-20 predicts risk of violence. We hypothesized that items on the DUNDRUM-1 and DUNDRUM-2 scales, rated at the time of pre-admission assessment, would predict length of stay in a medium secure forensic hospital setting.

  19. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Limerick

    LENUS (Irish Health Repository)

    O Caoimh, Rónán

    2014-09-19

    Functional decline and frailty are common in community dwelling older adults, increasing the risk of adverse outcomes. Given this, we investigated the prevalence of frailty-associated risk factors and their distribution according to the severity of perceived risk in a cohort of community dwelling older adults, using the Risk Instrument for Screening in the Community (RISC).

  20. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    O'Daly, Brendan J

    2009-06-01

    BACKGROUND: Predicting the clinical course in adhesional small bowel obstruction is difficult. There are no validated clinical or radiologic features that allow early identification of patients likely to require surgical intervention. METHODS: We conducted a retrospective review of 100 patients consecutively admitted to a tertiary level teaching hospital over a 3-year period (2002-2004) who had acute adhesional small bowel obstruction and underwent computed tomography (CT). The primary outcomes that we assessed were conservative management or the need for surgical intervention. We investigated time to physiologic gastrointestinal function recovery as a secondary outcome. We examined independent predictors of surgical intervention in a bivariate analysis using a stepwise logistic regression analysis. RESULTS: Of the 100 patients investigated, we excluded 12. Of the 88 remaining patients, 58 (66%) were managed conservatively and 30 (34%) underwent surgery. Peritoneal fluid detected on a CT scan (n = 37) was associated more frequently with surgery than conservative management (46% v. 29%, p = 0.046, chi(2)). Logistical regression identified peritoneal fluid detected on a CT scan as an independent predictor of surgical intervention (odds ratio 3.0, 95% confidence interval 1.15-7.84). CONCLUSION: The presence of peritoneal fluid on a CT scan in patients with adhesional small bowel obstruction is an independent predictor of surgical intervention and should alert the clinician that the patient is 3 times more likely to require surgery.

  1. Sibling support : The exchange of help among brothers and sisters in the Netherlands

    NARCIS (Netherlands)

    Voorpostel, Marieke Brenda Judith

    2007-01-01

    The bond with a sibling is potentially the longest lasting of all personal relationships. Siblings play a significant part in each other's lives over the entire life course. They are drawn together because they share a genetic, family, social class and historic background, but they are also

  2. What We Learn from Our Sisters and Brothers: For Better or for Worse

    Science.gov (United States)

    Kramer, Laurie; Conger, Katherine J.

    2009-01-01

    Siblings have considerable influence on one another's development throughout childhood, yet most human development research has neglected sibling socialization. Through this volume, we aim to enhance our understanding of how siblings play formative roles in one another's social and emotional development. We examine the mechanisms by which children…

  3. ALWAYS THE LITTLE BROTHER? DIGITAL-PRODUCT INNOVATION IN THE MEDIA SECTOR

    OpenAIRE

    HANNA-KAISA ELLONEN; PIIA KARHU

    2006-01-01

    This article concerns digital-product innovation within the media sector. From previous literature we identify eight factors affecting innovation work. Using material from narratives collected from experts within the media industry, we then present a specific framework that summarizes the factors affecting digital innovations either negatively or positively. We identify three underlying phenomena in the Finnish media sector that explain its specific features: First, it is a small market with ...

  4. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    May, Carl R

    2011-09-30

    Abstract Background Normalization Process Theory (NPT) can be used to explain implementation processes in health care relating to new technologies and complex interventions. This paper describes the processes by which we developed a simplified version of NPT for use by clinicians, managers, and policy makers, and which could be embedded in a web-enabled toolkit and on-line users manual. Methods Between 2006 and 2010 we undertook four tasks. (i) We presented NPT to potential and actual users in multiple workshops, seminars, and presentations. (ii) Using what we discovered from these meetings, we decided to create a simplified set of statements and explanations expressing core constructs of the theory (iii) We circulated these statements to a criterion sample of 60 researchers, clinicians and others, using SurveyMonkey to collect qualitative textual data about their criticisms of the statements. (iv) We then reconstructed the statements and explanations to meet users\\' criticisms, embedded them in a web-enabled toolkit, and beta tested this \\'in the wild\\'. Results On-line data collection was effective: over a four week period 50\\/60 participants responded using SurveyMonkey (40\\/60) or direct phone and email contact (10\\/60). An additional nine responses were received from people who had been sent the SurveyMonkey form by other respondents. Beta testing of the web enabled toolkit produced 13 responses, from 327 visits to http:\\/\\/www.normalizationprocess.org. Qualitative analysis of both sets of responses showed a high level of support for the statements but also showed that some statements poorly expressed their underlying constructs or overlapped with others. These were rewritten to take account of users\\' criticisms and then embedded in a web-enabled toolkit. As a result we were able translate the core constructs into a simplified set of statements that could be utilized by non-experts. Conclusion Normalization Process Theory has been developed through transparent procedures at each stage of its life. The theory has been shown to be sufficiently robust to merit formal testing. This project has provided a user friendly version of NPT that can be embedded in a web-enabled toolkit and used as a heuristic device to think through implementation and integration problems.

  5. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    O' Leary, Niall D

    2011-10-13

    Abstract Background Styrene is a toxic and potentially carcinogenic alkenylbenzene used extensively in the polymer processing industry. Significant quantities of contaminated liquid waste are generated annually as a consequence. However, styrene is not a true xenobiotic and microbial pathways for its aerobic assimilation, via an intermediate, phenylacetic acid, have been identified in a diverse range of environmental isolates. The potential for microbial bioremediation of styrene waste has received considerable research attention over the last number of years. As a result the structure, organisation and encoded function of the genes responsible for styrene and phenylacetic acid sensing, uptake and catabolism have been elucidated. However, a limited understanding persists in relation to host specific regulatory molecules which may impart additional control over these pathways. In this study the styrene degrader Pseudomonas putida CA-3 was subjected to random mini-Tn5 mutagenesis and mutants screened for altered styrene\\/phenylacetic acid utilisation profiles potentially linked to non-catabolon encoded regulatory influences. Results One mutant, D7, capable of growth on styrene, but not on phenylacetic acid, harboured a Tn5 insertion in the rpoN gene encoding σ54. Complementation of the D7 mutant with the wild type rpoN gene restored the ability of this strain to utilise phenylacetic acid as a sole carbon source. Subsequent RT-PCR analyses revealed that a phenylacetate permease, PaaL, was expressed in wild type P. putida CA-3 cells utilising styrene or phenylacetic acid, but could not be detected in the disrupted D7 mutant. Expression of plasmid borne paaL in mutant D7 was found to fully restore the phenylacetic acid utilisation capacity of the strain to wild type levels. Bioinformatic analysis of the paaL promoter from P. putida CA-3 revealed two σ54 consensus binding sites in a non-archetypal configuration, with the transcriptional start site being resolved by primer extension analysis. Comparative analyses of genomes encoding phenylacetyl CoA, (PACoA), catabolic operons identified a common association among styrene degradation linked PACoA catabolons in Pseudomonas species studied to date. Conclusions In summary, this is the first study to report RpoN dependent transcriptional activation of the PACoA catabolon paaL gene, encoding a transport protein essential for phenylacetic acid utilisation in P. putida CA-3. Bioinformatic analysis is provided to suggest this regulatory link may be common among styrene degrading Pseudomonads.

  6. Two brothers that don't look very similar; Zwei ungleiche Brueder

    Energy Technology Data Exchange (ETDEWEB)

    Jantzen, Markus

    2009-01-15

    At first glance, the Tesla Roadster and the Elektro-Smart seem to have nothing in common, apart from the fact that they are both electric vehicles. However, the comparison is not as foolish as it seems. (orig.)

  7. Beyond Bad Behaving Brothers: Productive Performances of Masculinities among College Fraternity Men

    Science.gov (United States)

    Harris, Frank, III; Harper, Shaun R.

    2014-01-01

    Research on fraternity men focuses almost exclusively on problematic behaviors such as homophobia and sexism, alcohol abuse, violence against women, sexual promiscuity, and the overrepresentation of members among campus judicial offenders. Consequently, little is known about those who perform masculinities in healthy and productive ways. Presented…

  8. Adolescents' Experiences 7 and 13 Months Following the Death of a Brother or Sister.

    Science.gov (United States)

    Brooten, Dorothy; Youngblut, JoAnne M; Roche, Rosa M

    2017-06-01

    This qualitative study used semi-structured interviews to describe adolescents' responses at 7 and 13 months to siblings' NICU/PICU/ED death. At 7 months, adolescents were asked about events around the sibling's death; at 7 and 13 months, about concerns/fears, feelings, and life changes. Seventeen adolescents participated (13-18 years; M=15); 65% Black, 24% Hispanic, 11% White. Themes included death circumstances, burial events, thinking about the deceased sibling, fears, and life changes. Adolescents reported shock and disbelief that the sibling died; 80% knew the reason for the death; many had difficulty getting through burials; all thought about the sibling. From 7 - 13 months fears increased including losing someone and thoughts of dying. Adolescents reported more changes in family life and greater life changes in them (more considerate, mature) by 13 months; some felt friends abandoned them after the sibling's death. Girls had more fears and changes in family life and themselves. Adolescent's responses to sibling death may not be visually apparent. One recommendation from this study is to ask adolescents how they are doing separately from parents since adolescents may hide feelings to protect their parents, especially their mothers. Older adolescents (14-18 years) and girls may have more difficulty after sibling death.

  9. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Harris, Paul

    2009-01-01

    A methodology is presented and validated through which long-term fixed site air quality measurements are used to characterise and remove temporal signals in sample-based measurements which have good spatial coverage but poor temporal resolution. The work has been carried out specifically to provide a spatial dataset of atmospheric ultrafine particle (UFP < 100 nm) data for ongoing epidemiologic cohort analysis but the method is readily transferable to wider epidemiologic investigations and research into the health effects of other pollutant species.

  10. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Mc Ardle, Angela

    2015-01-01

    Joint destruction, as evidenced by radiographic findings, is a significant problem for patients suffering from rheumatoid arthritis and psoriatic arthritis. Inherently irreversible and frequently progressive, the process of joint damage begins at and even before the clinical onset of disease. However, rheumatoid and psoriatic arthropathies are heterogeneous in nature and not all patients progress to joint damage. It is therefore important to identify patients susceptible to joint destruction in order to initiate more aggressive treatment as soon as possible and thereby potentially prevent irreversible joint damage. At the same time, the high cost and potential side effects associated with aggressive treatment mean it is also important not to over treat patients and especially those who, even if left untreated, would not progress to joint destruction. It is therefore clear that a protein biomarker signature that could predict joint damage at an early stage would support more informed clinical decisions on the most appropriate treatment regimens for individual patients. Although many candidate biomarkers for rheumatoid and psoriatic arthritis have been reported in the literature, relatively few have reached clinical use and as a consequence the number of prognostic biomarkers used in rheumatology has remained relatively static for several years. It has become evident that a significant challenge in the transition of biomarker candidates to clinical diagnostic assays lies in the development of suitably robust biomarker assays, especially multiplexed assays, and their clinical validation in appropriate patient sample cohorts. Recent developments in mass spectrometry-based targeted quantitative protein measurements have transformed our ability to rapidly develop multiplexed protein biomarker assays. These advances are likely to have a significant impact on the validation of biomarkers in the future. In this review, we have comprehensively compiled a list of candidate biomarkers in rheumatoid and psoriatic arthritis, evaluated the evidence for their potential as biomarkers of bone (joint) damage, and outlined how mass spectrometry-based targeted and multiplexed measurement of candidate biomarker proteins is likely to accelerate their clinical validation and the development of clinical diagnostic tests.

  11. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Mc Manus, Vicki

    2008-01-01

    BACKGROUND: Cerebral palsy (CP) is the most common cause of physical disability in children but its impact on quality of life is not well understood. This study examined participation in everyday activities among children without CP and children with mild, moderate and severe impairment due to CP. We then examined ten domains of quality of life in children with CP and investigated whether participation in everyday activities was associated with improved quality of life independent of gender, age and level of impairment. METHODS: This was a cross-sectional study of children aged 8-12 years based on two questionnaires, frequency of participation (FPQ) and KIDSCREEN, completed by parents of 98 children on the South of Ireland Cerebral Palsy Register (response rate = 82%) and parents of 448 children attending two Cork city schools (response rate = 69%) who completed one questionnaire (FPQ). Multiple linear regression was used: firstly to estimate the effect of severity of CP on participation in everyday activities independent of age and gender and secondly we estimated the effect of participation on quality of life independent of age gender and level of impairment. RESULTS: Participation in 11 of the 14 everyday activities examined varied across the children without CP and the children with varying severity of CP. In general, increased impairment decreased participation. Independent of age and gender, there was a highly significant decrease in overall participation with a fall of -6.0 (95% CI = -6.9 to -5.2) with each increasing level of impairment. The children with CP generally had high quality of life. Increased impairment was associated with diminished quality of life in just two domains - Physical well-being and Social support and peers. Overall participation in everyday activities was significantly associated with quality of life in 3 of the 10 domains (Physical well-being, Social support and peers & Moods and emotions) in analysis adjusted for gender age and level of impairment. CONCLUSION: While increased impairment due to CP restricts participation in the majority of everyday activities, the level of participation has a limited effect on the quality of life of the children with CP in age 8-12 years.

  12. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Hurley, Deirdre A

    2010-01-01

    Sleep disturbance is becoming increasingly recognised as a clinically important symptom in people with chronic low back pain (CLBP, low back pain >12 weeks), associated with physical inactivity and depression. Current research and international clinical guidelines recommend people with CLBP assume a physically active role in their recovery to prevent chronicity, but the high prevalence of sleep disturbance in this population may be unknowingly limiting their ability to participate in exercise-based rehabilitation programmes and contributing to poor outcomes. There is currently no knowledge concerning the effectiveness of physiotherapy on sleep disturbance in people with chronic low back pain and no evidence of the feasibility of conducting randomized controlled trials that comprehensively evaluate sleep as an outcome measure in this population.

  13. 3 CFR 8466 - Proclamation 8466 of December 16, 2009. Wright Brothers Day, 2009

    Science.gov (United States)

    2010-01-01

    ... alter our world. Today, we honor the enduring American spirit of creativity and innovation that made the.... In these challenging times, the story of Orville and Wilbur Wright reminds us of what can be accomplished when imagination is joined with tenacity. Their spirit lives on in every garage and basement...

  14. The Failure of Lehman Brothers and Merril Lynch: A Lesson for the ...

    African Journals Online (AJOL)

    Also the conventional lending procedures were not instituted rather they depend on subprime mortgage arrangement that did not have collateral securities. The declining home prices had made refinancing more difficult as a result of inadequate innovations in securitization. We therefore, recommended that the regulatory ...

  15. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Casey, Jillian P

    2015-01-01

    Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder characterised by abnormal ciliary motion and impaired mucociliary clearance, leading to recurrent respiratory infections, sinusitis, otitis media and male infertility. Some patients also have laterality defects. We recently reported the identification of three disease-causing PCD genes in the Irish Traveller population; RSPH4A, DYX1C1 and CCNO. We have since assessed an additional Irish Traveller family with a complex phenotype involving PCD who did not have any of the previously identified PCD mutations.

  16. Rac1 and Rac3 in cell morphology and adhesion : brothers and foes

    NARCIS (Netherlands)

    Hajdo-Milašinović, A.

    2010-01-01

    Ondanks een hoge mate van homologie verschillen de kleine Rho GTPases Rac1 en Rac3 wezenlijk in de functie die ze uitoefenen. De beschreven verschillen in effecten op cell-matrix adhesie berust op het feit dat Rac1 en Rac3 onafhankelijk van elkaar en op een andere manier aan het multifunctionele

  17. Big Brother Or Trusted Allies How The Police Can Earn Community Support For Using Unmanned Aircraft

    Science.gov (United States)

    2017-12-01

    the American public can both benefit from and be threatened by law enforcement’s use of drones, the challenge for police, sheriff’s departments, and...technology.16 The report notes that technology can bring both benefits and risks for law enforcement agencies in their public safety and crime fighting...should “engage and educate communities” in a transparent dialogue about the costs and benefits , potential privacy risks, and accountability measures

  18. Power in Play: A Foucauldian Reading of A.O. Soyinka's "The Trials of Brother Jero"

    Science.gov (United States)

    Davoodifar, Mahboobeh; Asl, Moussa Pourya

    2015-01-01

    This work utilizes Foucault's articulations on the power strategies of our contemporary society. To him the subject's constitution is never a purely passive effect of power on the subject but requires the subject's own activity. This necessitates the existence of a dynamic, mutually affecting relationship, implying that one can be both dominated…

  19. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    O'Neill, Sinéad M

    2017-02-27

    Caesarean section (CS) rates are increasing worldwide and as a result repeat CS is common. The optimal mode of delivery in women with one previous CS is widely debated and the risks to the infant are understudied. The aim of the current study was to evaluate if women with a trial of labour after caesarean (TOLAC) had an increased odds of neonatal and infant death compared to women with an elective repeat CS (ERCS).

  20. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Holton, Alice E

    2017-11-08

    Older adults are particularly vulnerable to adverse effects from concurrent alcohol and medication use. However, there is limited evidence regarding the prevalence of these adverse outcomes among older adults, and there is a lack of consensus regarding what constitutes an alcohol-interactive medicine. The objective of this study was to develop an explicit list of potentially serious alcohol-medication interactions for use in older adults.

  1. First-person shooter games as a way of connecting to people: "brothers in blood".

    Science.gov (United States)

    Frostling-Henningsson, Maria

    2009-10-01

    This work seeks to understand young adults' motives for online gaming and extends previous research concerning social interaction in virtual contexts. The focus of the study is on Counter-Strike and World of Warcraft. Drawing on Baudrillard's concept of simulacra, an analysis of young gamers' motivation for gaming is carried out. The empirical data was generated employing a mix of qualitative methods such as researcher introspection, observation, and interviews with young adults in two different online gaming centers in Stockholm during 2006 and 2007. The results show that online gaming is foremost motivated by social reasons providing the gamers with a possibility of cooperation and communication. Some of the gamers in the study were motivated by escapism. Online gaming also provides gamers with an experience in which "flow" can be obtained and serves as a "hallucination of the real," making it possible to do things and try out behaviors that would be impossible to do or try in real life. The gamers felt that online gaming gave them more experiences than real life could provide. For research purposes, this work provides a better understanding of the motivational aspects for gamers.

  2. The zombie and his italian half brother: the satiric use of the zombie ...

    African Journals Online (AJOL)

    ... italiana degli anni Novanta, caratterizzata da un consumismo banale e popolata di giovani ossessionati dalla moda e dalla pubblicità. Il saggio si propone di analizzare il racconto nell'ambito del pulp italiano definendone le originali tecniche di demistificazione. Key Words: Pulp Fiction – Gothic Novel – Consumerism ...

  3. Phelan-McDermid syndrome in two adult brothers: Atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    Verhoeven, W.M.A.; Egger, J.I.M.; Willemsen, M.H.; Leijer, G.J.M. de; Kleefstra, T.

    2012-01-01

    The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances,

  4. Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    Verhoeven, W.M.; Egger, J.I.; Willemsen, M.H.; de Leijer, G.J.; Kleefstra, T.

    2012-01-01

    The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances,

  5. Adjustment, Sibling Problems and Coping Strategies of Brothers and Sisters of Children with Autistic Spectrum Disorder

    Science.gov (United States)

    Ross, Penelope; Cuskelly, Monica

    2006-01-01

    Background: Siblings of children with autistic spectrum disorder (ASD) express more problem behaviours and experience more difficulties in their relationships than do children in families where all children are developing typically. We know little about what contributes to these difficulties. Method: Mothers of a child with ASD completed the…

  6. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    McCarthy, E M

    2011-11-15

    Patients with inflammatory arthritis are at increased risk of vaccine preventable infections. This risk is increased by immunomodulatory therapies. Vaccination for influenza and pneumococcal disease reduces the risk. Severe cases of varicella infection have occurred in patients on biologic therapies. We sought to identify vaccination rates for commonly acquired infections and to ascertain varicella immune status in patients with inflammatory arthritis. 100 patients with inflammatory arthritis were administered a standardised questionnaire. Data collected included age, diagnosis, vaccination history, history of varicella, treatment and the presence of other indications for vaccination. 58 patients (58%) had not received the influenza vaccine in the past year. Only 19 patients (19%) had ever received pneumococcal vaccine. Anti TNF use did not predict vaccination (p = .46). An increasing number of co morbid conditions predicted both pneumococcal (p < 0.003) and influenza vaccine (p < 0.03) administration. Nineteen patients (19%) gave no history of varicella infection, none having had varicella titres checked pre treatment. Immunisation rates in patients with inflammatory arthritis on immunosuppressive therapies are low. Immunisation schedules should be available for each patient during rheumatology and general practice consultations.

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    McHugh, Seamus M

    2009-01-01

    AIMS: We will examine the latest advances in genomic and proteomic laboratory technology. Through an extensive literature review we aim to critically appraise those studies which have utilized these latest technologies and ascertain their potential to identify clinically useful biomarkers. METHODS: An extensive review of the literature was carried out in both online medical journals and through the Royal College of Surgeons in Ireland library. RESULTS: Laboratory technology has advanced in the fields of genomics and oncoproteomics. Gene expression profiling with DNA microarray technology has allowed us to begin genetic profiling of colorectal cancer tissue. The response to chemotherapy can differ amongst individual tumors. For the first time researchers have begun to isolate and identify the genes responsible. New laboratory techniques allow us to isolate proteins preferentially expressed in colorectal cancer tissue. This could potentially lead to identification of a clinically useful protein biomarker in colorectal cancer screening and treatment. CONCLUSION: If a set of discriminating genes could be used for characterization and prediction of chemotherapeutic response, an individualized tailored therapeutic regime could become the standard of care for those undergoing systemic treatment for colorectal cancer. New laboratory techniques of protein identification may eventually allow identification of a clinically useful biomarker that could be used for screening and treatment. At present however, both expression of different gene signatures and isolation of various protein peaks has been limited by study size. Independent multi-centre correlation of results with larger sample sizes is needed to allow translation into clinical practice.

  8. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Jerjes, Waseem K

    2011-08-23

    Abstract While histopathology of excised tissue remains the gold standard for diagnosis, several new, non-invasive diagnostic techniques are being developed. They rely on physical and biochemical changes that precede and mirror malignant change within tissue. The basic principle involves simple optical techniques of tissue interrogation. Their accuracy, expressed as sensitivity and specificity, are reported in a number of studies suggests that they have a potential for cost effective, real-time, in situ diagnosis. We review the Third Scientific Meeting of the Head and Neck Optical Diagnostics Society held in Congress Innsbruck, Innsbruck, Austria on the 11th May 2011. For the first time the HNODS Annual Scientific Meeting was held in association with the International Photodynamic Association (IPA) and the European Platform for Photodynamic Medicine (EPPM). The aim was to enhance the interdisciplinary aspects of optical diagnostics and other photodynamic applications. The meeting included 2 sections: oral communication sessions running in parallel to the IPA programme and poster presentation sessions combined with the IPA and EPPM posters sessions.

  9. Siblings: Brothers and Sisters of People Who Have Mental Retardation. Arc Q & A Series.

    Science.gov (United States)

    Arc, Arlington, TX.

    Basic information about siblings of people with mental retardation is presented in a question-and-answer format. The following questions are addressed: "Is having a sibling with a disability different than having a sibling who does not have a disability?"; "What are some of the concerns of siblings of people with disabilities?"; "Are there any…

  10. My Brother's Keeper: A New Phase in the Debate on Corporate Responsibility

    NARCIS (Netherlands)

    Wempe, J.F.D.B.; Slingerland, Willeke; Rendtorff, Jacob Dahl

    2017-01-01

    In this article, we analyse whether it is possible to hold a loosely organised collective responsible for the effects it has on others. We consider the possibility of holding a loosely organised collective responsible by comparing it with a well-organised collective such as a corporation, a joint

  11. A designated centre for people with disabilities, operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Hickey, Anne

    2009-01-01

    BACKGROUND: Stroke is a leading cause of death and functional impairment. While older people are particularly vulnerable to stroke, research suggests that they have the poorest awareness of stroke warning signs and risk factors. This study examined knowledge of stroke warning signs and risk factors among community-dwelling older adults. METHODS: Randomly selected community-dwelling older people (aged 65+) in Ireland (n = 2,033; 68% response rate). Participants completed home interviews. Questions assessed knowledge of stroke warning signs and risk factors, and personal risk factors for stroke. RESULTS: Of the overall sample, 6% had previously experienced a stroke or transient ischaemic attack. When asked to identify stroke risk factors from a provided list, less than half of the overall sample identified established risk factors (e.g., smoking, hypercholesterolaemia), hypertension being the only exception (identified by 74%). Similarly, less than half identified established warning signs (e.g., weakness, headache), with slurred speech (54%) as the exception. Overall, there were considerable gaps in awareness with poorest levels evident in those with primary level education only and in those living in Northern Ireland (compared with Republic of Ireland). CONCLUSION: Knowledge deficits in this study suggest that most of the common early symptoms or signs of stroke were recognized as such by less than half of the older adults surveyed. As such, many older adults may not recognise early symptoms of stroke in themselves or others. Thus, they may lose vital time in presenting for medical attention. Lack of public awareness about stroke warning signs and risk factors must be addressed as one important contribution to reducing mortality and morbidity from stroke.

  12. When Your Brother or Sister Has Cancer: A Guide for Teens

    Science.gov (United States)

    ... h _ _ e I _ _ n _ t _ d v ee _ _ ai l _ t _ o _ r _ Tn e ydso _ _ o ... support group. 76 The best thing about the future is that it comes Chapter 11 After Treatment ... exactly how you will feel. But when the future is so uncertain, teens say that it helps ...

  13. Kaks kirja vennale = Two Letters from Vincent van Gogh to his brother / Vincent van Gogh

    Index Scriptorium Estoniae

    Gogh, Vincent van, 1853-1890

    2008-01-01

    Kunstnik Vincent van Goghi kaks kirja oma vennale Theole. Tõlge vene keelest ja kommentaar Mehis Heinsaarelt. Ingliskeelsed kirjad raamatust "The Complete Letters of Vincent van Gogh", Thames and Hudson, 1979

  14. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Buckley, B S

    2011-12-12

    Background:  Gestational diabetes mellitus is a potentially serious condition that affects many pregnancies and its prevalence is increasing. Evidence suggests early detection and treatment improves outcomes, but this is hampered by continued disagreement and inconsistency regarding many aspects of its diagnosis. Methods:  The Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention (DALI) research programme aims to promote pan-European standards in the detection and diagnosis of gestational diabetes and to develop effective preventive interventions. To provide an overview of the context within which the programme will be conducted and its findings interpreted, systematic searching and narrative synthesis have been used to identify and review the best available European evidence relating to the prevalence of gestational diabetes, current screening practices and barriers to screening. Results:  Prevalence is most often reported as 2-6% of pregnancies. Prevalence may be lower towards the Northern Atlantic seaboard of Europe and higher in the Southern Mediterranean seaboard. Screening practice and policy is inconsistent across Europe, hampered by lack of consensus on testing methods, diagnostic glycaemic thresholds and the value of routine screening. Poor clinician awareness of gestational diabetes, its diagnosis and local clinical guidelines further undermine detection of gestational diabetes. Conclusions:  Europe-wide agreement on screening approaches and diagnostic standards for gestational diabetes could lead to better detection and treatment, improved outcomes for women and children and a strengthened evidence base. There is an urgent need for well-designed research that can inform decisions on best practice in gestational diabetes mellitus screening and diagnosis. © 2011 The Authors. Diabetic Medicine© 2011 Diabetes UK.

  15. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    O'Mahoney, S

    2012-06-01

    AJ Cronin (1896-1981) was a Scottish-born doctor-turned-novelist whose most famous novel is The Citadel, published in 1937. The book describes the struggles of an idealistic young doctor working in Wales and London in the 1920s and 30s. The novel was a global bestseller and its portrayal of a largely ineffective, corruption-ridden system of healthcare is thought to have directly influenced the foundation of the National Health Service in 1948. The Citadel anticipates such phenomena as evidence-based medicine and continuing medical education. This paper argues that the novel was never intended as propaganda for a state-controlled national health service. On the contrary, Cronin was against state control. Analysis of the novel is informed by recent biographical revelations about Cronin and the blurring of the margin between fact and fiction in Cronin\\'s life and work is examined.

  16. When big brother is watching: goal orientation shapes reactions to electronic monitoring during online training.

    Science.gov (United States)

    Watson, Aaron M; Foster Thompson, Lori; Rudolph, Jane V; Whelan, Thomas J; Behrend, Tara S; Gissel, Amanda L

    2013-07-01

    Web-based training is frequently used by organizations as a convenient and low-cost way to teach employees new knowledge and skills. As web-based training is typically unproctored, employees may be held accountable to the organization by computer software that monitors their behaviors. The current study examines how the introduction of electronic performance monitoring may provoke negative emotional reactions and decrease learning among certain types of e-learners. Through motivated action theory and trait activation theory, we examine the role of performance goal orientation when e-learners are exposed to asynchronous and synchronous monitoring. We show that some e-learners are more susceptible than others to evaluation apprehension when they perceive their activities are being monitored electronically. Specifically, e-learners higher in avoid performance goal orientation exhibited increased evaluation apprehension if they believed asynchronous monitoring was present, and they showed decreased skill attainment as a result. E-learners higher on prove performance goal orientation showed greater evaluation apprehension if they believed real-time monitoring was occurring, resulting in decreased skill attainment. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  17. Is big brother watching you? Responding to tagging and tracking in dementia care

    OpenAIRE

    Plastow, N A

    2006-01-01

    The increased availability of assistive technologies, particularly tagging and tracking technology, raises questions for occupational therapists working in dementia care. As experts in environmental adaptation to support participation, occupational therapists need to be clear about what technologies are available to address wandering behaviour, how emerging technologies will be used in their practice, and how they will proactively respond to the ethical issues involved in these technologies. ...

  18. Is Big Brother Watching the Wired Campus? Information Technologies Undermine the Climate of Freedom in Academia.

    Science.gov (United States)

    Earls, Alan R.

    2000-01-01

    Explores privacy issues raised by information technology at colleges and universities. Drawing on accounts and opinions of faculty and staff members, provides examples of current practices and policies on Internet and e-mail use and discusses the possible need for more developed policies. (EV)

  19. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Limerick

    LENUS (Irish Health Repository)

    O'Reilly, Ken

    2015-07-10

    There is a broad literature suggesting that cognitive difficulties are associated with violence across a variety of groups. Although neurocognitive and social cognitive deficits are core features of schizophrenia, evidence of a relationship between cognitive impairments and violence within this patient population has been mixed.

  20. De digitale stresscoach : totale controle over je mentale gezondheid of Big Brother is watching you?

    NARCIS (Netherlands)

    Lieshout, M. van; Wiezer, N.; Korte, E. de

    2014-01-01

    Een digitale coach die je helpt stress op je werk te verminderen en meer energie uit je werk te halen klinkt aantrekkelijk. Stress ervaren we immers allemaal. Net zoals we allemaal streven naar werk waar je energie van krijgt. En stress vermijden we liever. Stress is een maatschappelijk probleem en

  1. Severe protein-calorie malnutrition in two brothers due to abuse by starvation.

    Science.gov (United States)

    Barroso, Marcela Montenegro Braga; Salvador, Luiza Martins; Fagundes Neto, Ulysses

    2016-12-01

    To describe the case of two siblings with severe protein-calorie malnutrition due to abuse by starvation. The two patients were simultaneously referred from the Municipal Hospital, where they were admitted to the Pediatric Gastroenterology clinic of a university hospital for diagnostic investigation of the cause of severe malnutrition and screening tests for Celiac Disease, Cystic Fibrosis and Environmental enteropathy among others. The exams were all normal, and after detailed research on the interactions of this family, we reached the conclusion that the malnutrition was due to abuse by starvation. The children spent approximately two months in the hospital, receiving a high-protein and high-calorie diet, with significant nutritional recovery. Abuse by starvation, although rare, should always be considered of as one of the causes of child malnutrition and pediatrician should be aware of the child's development, as well as the family interactions, to prevent more severe nutritional and emotional consequences in the future. Copyright © 2016. Publicado por Elsevier Editora Ltda.

  2. Family-focused prevention with Latinos: What about sisters and brothers?

    Science.gov (United States)

    Updegraff, Kimberly A; Umaña-Taylor, Adriana J; Rodríguez De Jesús, Sue A; McHale, Susan M; Feinberg, Mark F; Kuo, Sally I-Chun

    2016-08-01

    Using a randomized, intent-to-treat design, this pilot study examined the feasibility and short-term effects of Siblings Are Special ( SIBS ) with a sample of 54 low-income Latino families (91% Mexican-origin). Participants were older (M = 10.8 years; SD = .46) and younger siblings (M = 8.4 years; SD = 1.13), and their parents (94% biological mothers), who were randomly assigned within school to the intervention (n = 28) or no-attention control (n = 26) condition. The intervention condition included 12 weekly afterschool sessions (90 min each) for sibling pairs and 3 family nights for parents and siblings (2 hr each). SIBS was designed to enhance sibling relationships via 2 primary intervention targets: (a) children’s capacities that underlie positive sibling dynamics, including relationship skills, cognitions, and shared activities; and (b) parenting of siblings, specifically, enhancing positive guidance and involvement and discouraging authoritarian control. Pre- and posttest data were gathered from siblings and parents. Recruitment and implementation data revealed high rates of attendance and completion, and high ratings of parent satisfaction with the program. Further, analyses suggested the program had positive effects of small to modest magnitude on posttest measures of sibling and parent–child relationship quality, parenting of siblings, older siblings’ emotional efficacy, and parents’ depressive symptoms and parenting stress, controlling for pretest levels of all outcomes and family background characteristics. Discussion addresses the feasibility of sibling-focused programs with low-income Latino families and makes recommendations for future research. PsycINFO Database Record (c) 2016 APA, all rights reserved

  3. Help a Brother Out: A Case Study in Multinational Intelligence Sharing, NATO SOF

    Science.gov (United States)

    2011-12-01

    timely 106 NSHQ COS briefing, October 20, 2010, and Alan Dron , “Special Network—Alliance Aims to Improve...BICES Communications & Information Systems Strategy, August 2011, 3, and Dron , “Special Network—Alliance Aims to Improve Cooperation among Special...and the Intelligence System.” International Journal of Intelligence and Counterintelligence 8, no. 4 (2005): 575–592. Dron , Alan. “Special Network

  4. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon

    LENUS (Irish Health Repository)

    Carew, Rosemarie M.

    2010-07-06

    Abstract Background Male Irs2-\\/- mice develop fatal type 2 diabetes at 13-14 weeks. Defects in neuronal proliferation, pituitary development and photoreceptor cell survival manifest in Irs2-\\/- mice. We identify retarded renal growth in male and female Irs2-\\/- mice, independent of diabetes. Results Kidney size and kidney:body weight ratio were reduced by approximately 20% in Irs2-\\/- mice at postnatal day 5 and was maintained in maturity. Reduced glomerular number but similar glomerular density was detected in Irs2-\\/- kidney compared to wild-type, suggesting intact global kidney structure. Analysis of insulin signalling revealed renal-specific upregulation of PKBβ\\/Akt2, hyperphosphorylation of GSK3β and concomitant accumulation of β-catenin in Irs2-\\/- kidney. Despite this, no significant upregulation of β-catenin targets was detected. Kidney-specific increases in Yes-associated protein (YAP), a key driver of organ size were also detected in the absence of Irs2. YAP phosphorylation on its inhibitory site Ser127 was also increased, with no change in the levels of YAP-regulated genes, suggesting that overall YAP activity was not increased in Irs2-\\/- kidney. Conclusions In summary, deletion of Irs2 causes reduced kidney size early in mouse development. Compensatory mechanisms such as increased β-catenin and YAP levels failed to overcome this developmental defect. These data point to Irs2 as an important novel mediator of kidney size.

  5. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Murphy, Andrew W

    2005-07-29

    BACKGROUND: The aim of the SPHERE study is to design, implement and evaluate tailored practice and personal care plans to improve the process of care and objective clinical outcomes for patients with established coronary heart disease (CHD) in general practice across two different health systems on the island of Ireland. CHD is a common cause of death and a significant cause of morbidity in Ireland. Secondary prevention has been recommended as a key strategy for reducing levels of CHD mortality and general practice has been highlighted as an ideal setting for secondary prevention initiatives. Current indications suggest that there is considerable room for improvement in the provision of secondary prevention for patients with established heart disease on the island of Ireland. The review literature recommends structured programmes with continued support and follow-up of patients; the provision of training, tailored to practice needs of access to evidence of effectiveness of secondary prevention; structured recall programmes that also take account of individual practice needs; and patient-centred consultations accompanied by attention to disease management guidelines. METHODS: SPHERE is a cluster randomised controlled trial, with practice-level randomisation to intervention and control groups, recruiting 960 patients from 48 practices in three study centres (Belfast, Dublin and Galway). Primary outcomes are blood pressure, total cholesterol, physical and mental health status (SF-12) and hospital re-admissions. The intervention takes place over two years and data is collected at baseline, one-year and two-year follow-up. Data is obtained from medical charts, consultations with practitioners, and patient postal questionnaires. The SPHERE intervention involves the implementation of a structured systematic programme of care for patients with CHD attending general practice. It is a multi-faceted intervention that has been developed to respond to barriers and solutions to optimal secondary prevention identified in preliminary qualitative research with practitioners and patients. General practitioners and practice nurses attend training sessions in facilitating behaviour change and medication prescribing guidelines for secondary prevention of CHD. Patients are invited to attend regular four-monthly consultations over two years, during which targets and goals for secondary prevention are set and reviewed. The analysis will be strengthened by economic, policy and qualitative components.

  6. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Kane, Bridget

    2009-08-01

    This paper provides an analysis of the collaborative work conducted at a multidisciplinary medical team meeting, where a patient’s definitive diagnosis is agreed, by consensus. The features that distinguish this process of diagnostic work by consensus are examined in depth. The current use of technology to support this collaborative activity is described, and experienced deficiencies are identified. Emphasis is placed on the visual and perceptual difficulty for individual specialities in making interpretations, and on how, through collaboration in discussion, definitive diagnosis is actually achieved. The challenge for providing adequate support for the multidisciplinary team at their meeting is outlined, given the multifaceted nature of the setting, i.e. patient management, educational, organizational and social functions, that need to be satisfied.

  7. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Masud, Tahir

    2014-09-01

    the rise in the number of older, frail adults necessitates that future doctors are adequately trained in the skills of geriatric medicine. Few countries have dedicated curricula in geriatric medicine at the undergraduate level. The aim of this project was to develop a consensus among geriatricians on a curriculum with the minimal requirements that a medical student should achieve by the end of medical school.

  8. My Brother’s Keeper: Forging SOF Operators Through Developmental Relationships

    Science.gov (United States)

    2016-06-01

    Representative comments: It starts with the seniors in each section, taking the time to do the right things. Some of the guys kind of overlook the mentor thing...difference when a guy knows that someone is available to help them develop. (E7, SEAL) The responsibility of mentoring goes on the senior , they have to...building, leadership, mentoring , mentorship 15. NUMBER OF PAGES 117 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY

  9. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Tipperary

    LENUS (Irish Health Repository)

    Amengual, Julià L

    2012-06-08

    AbstractBackgroundWe report the case of a chronic stroke patient (62 months after injury) showing total absence of motor activity evoked by transcranial magnetic stimulation (TMS) of spared regions of the left motor cortex, but near-to-complete recovery of motor abilities in the affected hand.Case presentationMultimodal investigations included detailed TMS based motor mapping, motor evoked potentials (MEP), and Cortical Silent period (CSP) as well as functional magnetic resonance imaging (fMRI) of motor activity, MRI based lesion analysis and Diffusion Tensor Imaging (DTI) Tractography of corticospinal tract (CST). Anatomical analysis revealed a left hemisphere subinsular lesion interrupting the descending left CST at the level of the internal capsule. The absence of MEPs after intense TMS pulses to the ipsilesional M1, and the reversible suppression of ongoing electromyographic (EMG) activity (indexed by CSP) demonstrate a weak modulation of subcortical systems by the ipsilesional left frontal cortex, but an inability to induce efficient descending volleys from those cortical locations to right hand and forearm muscles. Functional MRI recordings under grasping and finger tapping patterns involving the affected hand showed slight signs of subcortical recruitment, as compared to the unaffected hand and hemisphere, as well as the expected cortical activations.ConclusionsThe potential sources of motor voluntary activity for the affected hand in absence of MEPs are discussed. We conclude that multimodal analysis may contribute to a more accurate prognosis of stroke patients.

  10. Back-breeding the aurochs: the Heck brothers, National Socialism and imagined geographies for nonhuman Lebensraum

    NARCIS (Netherlands)

    Driessen, C.P.G.; Lorimer, J.

    2016-01-01

    This chapter investigates the bio-geographical imaginations behind the animal 'back-breeding' programs carried out by Lutz and Heinz Heck - two influential German zoologists who ran Berlin and Munich zoos. Partly with close connections to and patronage from the National Socialist elite, the Heck

  11. TALKING POLITICS ONLINE WITHIN SPACES OF POPULAR CULTURE : THE CASE OF THE BIG BROTHER FORUM

    NARCIS (Netherlands)

    Graham, T.S.

    2010-01-01

    Talking politics online is not bound to spaces dedicated to politics, particularly the everyday political talk crucial to the public sphere. The aim of this article is to move beyond such spaces by examining political talk within a space dedicated to popular culture. The purpose is to see whether a

  12. "The Two Brothers": Reconciling Perceptual-Cognitive and Statistical Models of Musical Evolution.

    Science.gov (United States)

    Jan, Steven

    2018-01-01

    While the "units, events and dynamics" of memetic evolution have been abstractly theorized (Lynch, 1998), they have not been applied systematically to real corpora in music. Some researchers, convinced of the validity of cultural evolution in more than the metaphorical sense adopted by much musicology, but perhaps skeptical of some or all of the claims of memetics, have attempted statistically based corpus-analysis techniques of music drawn from molecular biology, and these have offered strong evidence in favor of system-level change over time (Savage, 2017). This article argues that such statistical approaches, while illuminating, ignore the psychological realities of music-information grouping, the transmission of such groups with varying degrees of fidelity, their selection according to relative perceptual-cognitive salience, and the power of this Darwinian process to drive the systemic changes (such as the development over time of systems of tonal organization in music) that statistical methodologies measure. It asserts that a synthesis between such statistical approaches to the study of music-cultural change and the theory of memetics as applied to music (Jan, 2007), in particular the latter's perceptual-cognitive elements, would harness the strengths of each approach and deepen understanding of cultural evolution in music.

  13. 77 FR 24554 - Culturally Significant Objects Imported for Exhibition; Determinations: “Quay Brothers: On...

    Science.gov (United States)

    2012-04-24

    ... display of the exhibit objects at The Museum of Modern Art, New York, NY, from on or about August 12, 2012... temporary exhibition within the United States, are of cultural significance. The objects are imported...

  14. The Failure of Lehman Brothers and Merril Lynch: A Lesson for the ...

    African Journals Online (AJOL)

    DR Nneka

    the United State America treasury securities market. Ahimie (2008) ... Thus, the above school of thought considered a bank failure as not when it ceases .... Lynch had further confirmed the historical fact that, no bank or financial institution is.

  15. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Tipperary

    LENUS (Irish Health Repository)

    2009-12-21

    Abstract Compelling evidence of major health benefits of fruit and vegetable consumption, physical activity, and outdoor interaction with \\'greenspace\\' have emerged in the past decade - all of which combine to give major potential health benefits from \\'grow-your-own\\' (GYO) in urban areas. However, neither current risk assessment models nor risk management strategies for GYO in allotments and gardens give any consideration to these health benefits, despite their potential often to more than fully compensate the risks. Although urban environments are more contaminated by heavy metals, arsenic, polyaromatic hydrocarbons and dioxins than most rural agricultural areas, evidence is lacking for adverse health outcomes of GYO in UK urban areas. Rarely do pollutants in GYO food exceed statutory limits set for commercial food, and few people obtain the majority of their food from GYO. In the UK, soil contamination thresholds triggering closure or remediation of allotment and garden sites are based on precautionary principles, generating \\'scares\\' that may negatively impact public health disproportionately to the actual health risks of exposure to toxins through own-grown food. By contrast, the health benefits of GYO are a direct counterpoint to the escalating public health crisis of \\'obesity and sloth\\' caused by eating an excess of saturated fats, inadequate consumption of fresh fruit and vegetables combined with a lack of exercise. These are now amongst the most important preventable causes of illness and death. The health and wider societal benefits of \\'grow-your-own\\' thus reveal a major limitation in current risk assessment methodologies which, in only considering risks, are unable to predict whether GYO on particular sites will, overall, have positive, negative, or no net effects on human health. This highlights a more general need for a new generation of risk assessment tools that also predict overall consequences for health to more effectively guide risk management in our increasingly risk-averse culture.

  16. Big brother - a fully automated control system for the DELPHI experiment

    International Nuclear Information System (INIS)

    Franek, B.; Sekulin, R.; Doenszelmann, M.; Gasper, C.; Charpentier, Jonker, M.

    1994-01-01

    The integrated control system of the DELPHI experiment is described. It allows the data to be taken in an almost automatic fashion. This is achieved by computer monitoring of the states of the LEP machine, the DELPHI subdetectors (SC) and the Data Acquisition System (DAS). Depending on these states, computer initiated actions are then taken. It has been designed using open-quote State Manager close-quote concept already used for local and central controls of DAS and SC

  17. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    MacGiobuin, S

    2017-08-01

    Food allergies are common in preschool children. This study’s aims are to establish prevalence, to clarify management practices, levels of preparedness and the perceived role of General Practitioners amongst Early Years Services providers. This study is an anonymous, quantitative, cross sectional study. An online questionnaire was distributed to 282 Early Years Service providers. Data were analysed using SPSS. Response rate was 35% (n=98). Prevalence of food allergy was 3% (n=119). Allergic reactions to food had occurred on site in 16% (n=15). Written emergency action plans were available in 47% of facilities (n=46). Medications were not kept on site in 63% (n=62) of facilities. General practitioners were felt to have an important role in the management of food allergies by 76% of respondents (n=61). This study identifies significant areas for improvement in the management of food allergic child in Early Years Services

  18. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Kamel, Dalia

    2012-11-01

    Being a significant health problem that affects patients in various age groups, breast cancer has been extensively studied to date. Recently, molecular breast cancer classification has advanced significantly with the availability of genomic profiling technologies. Proteomic technologies have also advanced from traditional protein assays including enzyme-linked immunosorbent assay, immunoblotting and immunohistochemistry to more comprehensive approaches including mass spectrometry and reverse phase protein lysate arrays (RPPA). The purpose of this manuscript is to review the current protein markers that influence breast cancer prediction and prognosis and to focus on novel advances in proteomic classification of breast cancer.

  19. "Brother Where Art Thou?" African American Male Instructors' Perceptions of the Counselor Education Profession

    Science.gov (United States)

    Brooks, Michael; Steen, Sam

    2010-01-01

    The purpose of this study was to investigate the perceptions of African American male counselor educators regarding the limited number of African American male faculty members in counselor education. Implications and suggestions on how universities can recruit and retain African American male faculty members are provided.

  20. "You Can Do Nasty Things to Your Brothers and Sisters without a Reason": Siblings' Backstage Behaviour

    Science.gov (United States)

    Punch, Samantha

    2008-01-01

    This article contributes to the recent, but still limited, literature on the sociology of sibship. It argues that during childhood the ambivalent love/hate nature of sibship is played out through the sharing of knowledge, time and space. It draws on the work of Goffman to illustrate that children's sibling interactions tend to consist of…

  1. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    2017-11-25

    Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the \\'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale\\' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother\\/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.

  2. Usher syndrome type I associated with bronchiectasis and immotile nasal cilia in two brothers.

    OpenAIRE

    Bonneau, D; Raymond, F; Kremer, C; Klossek, J M; Kaplan, J; Patte, F

    1993-01-01

    Usher syndrome type I is an autosomal recessive disease characterised by congenital sensorineural deafness, involvement of the vestibular system, and progressive visual loss owing to retinitis pigmentosa. Here we report the association of this disease with bronchiectasis, chronic sinusitis, and reduced nasal mucociliary clearance in two sibs and we suggest Usher syndrome type I could be a primary ciliary disorder.

  3. A designated centre for people with disabilities operated by Brothers of Charity Services Galway

    LENUS (Irish Health Repository)

    Briggs, R

    2017-05-01

    Several commonly completed tests have low diagnostic yield in the setting of transient loss of consciousness (T-LOC). We estimated the use and cost of inappropriate investigations in patients admitted with T-LOC and assessed if these patients were given a definitive diagnosis for their presentation. We identified 80 consecutive patients admitted with T-LOC to a university teaching hospital. Eighty-eight percent (70\\/80) had a computerized topography (CT) brain scan and 49% (34\\/70) of these scans were inappropriate based on standard guidelines. Almost half (17\\/80) of electroencephalograms (EEG) and 82% (9\\/11) of carotid doppler ultrasound performed were not based on clinical evidence of seizure or stroke respectively. Forty-four percent (35\\/80) of patients had no formal diagnosis documented for their presentation. Inappropriate investigation in T-LOC is very prevalent in the acute hospital, increasing cost of patient care. In addition, there is poor diagnostic formulation for T-LOC making recurrent events more likely in the absence of definitive diagnoses

  4. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Kilkenny

    LENUS (Irish Health Repository)

    McLoughlin, Kathleen

    2015-11-24

    For most people, home is the preferred place of care and death. Despite the development of specialist palliative care and primary care models of community based service delivery, people who are dying, and their families\\/carers, can experience isolation, feel excluded from social circles and distanced from their communities. Loneliness and social isolation can have a detrimental impact on both health and quality of life. Internationally, models of social and practical support at the end of life are gaining momentum as a result of the Compassionate Communities movement. These models have not yet been subjected to rigorous evaluation. The aims of the study described in this protocol are: (1) to evaluate the feasibility, acceptability and potential effectiveness of The Good Neighbour Partnership (GNP), a new volunteer-led model of social and practical care\\/support for community dwelling adults in Ireland who are living with advanced life-limiting illness; and (2) to pilot the method for a Phase III Randomised Controlled Trial (RCT).

  5. Phelan-McDermid syndrome in two adult brothers: Atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    W.M.A. Verhoeven (Wim); J.I.M. Egger (Jos); M.H. Willemsen; G.J.M. de Leijer (Gert); T. Kleefstra (Tjitske)

    2012-01-01

    textabstractThe 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep

  6. Modifiable environmental influences on body mass index shared by young adult brothers

    DEFF Research Database (Denmark)

    Rokholm, B; Silventoinen, K; Tynelius, P

    2013-01-01

    Twin and adoption studies suggest that family environment has little, if any, influence on body mass index (BMI) in adulthood. We investigated the hypothesis that the differences in the years of birth between siblings influence their similarity in BMI at comparable ages, which would give evidence...... for a possibly modifiable influence of the environment shared by family members....

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    McGrath, Bridget

    2012-01-01

    This study explored registered psychiatric nurses\\' (RPNs\\') interactions and level of empathy towards service users with a diagnosis of borderline personality disorder (BPD). A qualitative approach was used, and 17 RPNs were interviewed using a semistructured interview schedule incorporating the "staff-patient interaction response scale" (SPIRS). Four themes emerged following data analysis: "challenging and difficult," "manipulative, destructive and threatening behaviour," "preying on the vulnerable resulting in splitting staff and other service users," and "boundaries and structure." Additionally, low levels of empathy were evident in the majority of participants\\' responses to the SPIRS. The findings provide further insight on nurses\\' empathy responses and views on caring for service users with BPD and further evidence for the need for training and education for nurses in the care of service users diagnosed with BPD.

  8. A designated centre for people with disabilities operated by Brothers of Charity Services Clare

    LENUS (Irish Health Repository)

    Murphy, Catriona

    2015-07-01

    This study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE).

  9. The Jesuit Republic and Brother Care in "The Mission": An Allegory of the Conquest

    Science.gov (United States)

    Vest, Jay Hansford C.

    2005-01-01

    "The Mission" is an award-winning film that presents an allegorical treatment of colonial drama in the Americas. Depicting the fabled "Jesuit Republic," the film dramatizes historical events that span a period of more than 150 years, from 1610 to 1768. In scope and deed these events bear much that is relevant to the invasion and conquest of the…

  10. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Hirpara, Kieran Michael

    2012-01-01

    Cervical spondylosis is a common and disabling condition. It is generally felt that the initial management should be nonoperative, and these modalities include physiotherapy, analgesia and selective nerve root injections. Surgery should be reserved for moderate to severe myelopathy patients who have failed a period of conservative treatment and patients whose symptoms are not adequately controlled by nonoperative means. A review of the literature supporting various modalities of conservative management is presented, and it is concluded that although effective, nonoperative treatment is labour intensive, requiring regular review and careful selection of medications and physical therapy on a case by case basis.

  11. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Hawton, Keith

    2011-06-10

    Abstract Background In order to reduce fatal self-poisoning legislation was introduced in the UK in 1998 to restrict pack sizes of paracetamol sold in pharmacies (maximum 32 tablets) and non-pharmacy outlets (maximum 16 tablets), and in Ireland in 2001, but with smaller maximum pack sizes (24 and 12 tablets). Our aim was to determine whether this resulted in smaller overdoses of paracetamol in Ireland compared with the UK. Methods We used data on general hospital presentations for non-fatal self-harm for 2002 - 2007 from the Multicentre Study of Self-harm in England (six hospitals), and from the National Registry of Deliberate Self-harm in Ireland. We compared sizes of overdoses of paracetamol in the two settings. Results There were clear peaks in numbers of non-fatal overdoses, associated with maximum pack sizes of paracetamol in pharmacy and non-pharmacy outlets in both England and Ireland. Significantly more pack equivalents (based on maximum non-pharmacy pack sizes) were used in overdoses in Ireland (mean 2.63, 95% CI 2.57-2.69) compared with England (2.07, 95% CI 2.03-2.10). The overall size of overdoses did not differ significantly between England (median 22, interquartile range (IQR) 15-32) and Ireland (median 24, IQR 12-36). Conclusions The difference in paracetamol pack size legislation between England and Ireland does not appear to have resulted in a major difference in sizes of overdoses. This is because more pack equivalents are taken in overdoses in Ireland, possibly reflecting differing enforcement of sales advice. Differences in access to clinical services may also be relevant.

  12. A designated centre for people with disabilities operated by Brothers of Charity Services Galway - Galway

    LENUS (Irish Health Repository)

    Foley, Geraldine

    2012-02-01

    Abstract Service providers and service users often have different perspectives on health and social care services. We have undertaken a systematic review of empirical data between 1988 and March 2011 relating to ALS service users\\' perspectives on health and social care services. Forty-seven texts were extracted and a narrative synthesis conducted. Few studies have explored ALS patients\\' experiences in relation to their satisfaction with services. Our review showed that ALS patients expect dignified care but they are often dissatisfied with health care services and have unmet expectations of their care. Most studies of decision-making and preferences for care have focused on end-of-life intervention. Various factors influence preferences for care from the service user perspective and people with ALS may adjust their use of services as they negotiate change. In conclusion, further research on the timeliness of services to meet changing needs of service users is required. The service user experience of allied health care services prior to end-of-life care also warrants investigation. Service providers need to support people with ALS as they negotiate feelings of acceptance and independence. Research to identify the key parameters of the ALS patient experience of services is required.

  13. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    O'Higgins, A

    2014-11-01

    The provision of high quality healthcare information about pregnancy is important to women and to healthcare professionals and it is 1 driven, in part, by a desire to improve clinical outcomes,. The objective of this study was to examine the use of digital media by women\\' to access pregnancy information. A questionnaire was distributed to women attending a large maternity hospital. Of the 522 respondents, the mean age was 31.8 years, 45% (235\\/522) were nulliparous, 62% (324\\/522) lived in the capital city and 29% (150\\/522) attended the hospital as private patients. Overall 95% (498\\/522) used the internet for pregnancy information, 76% (399\\/522) had a smartphone and 59% (235\\/399) of smartphone owners had used a pregnancy smartapp. The nature of internet usage for pregnancy information included discussion forums (70%), social networks (67%), video media (48%), e-books (15%), blogs (13%), microblogs (9%) and podcasts (4%). Even women who were socially disadvantaged reported high levels of digital media usage. In contemporary maternity care women use digital media extensively for pregnancy information. All maternity services should have a digital media strategy.

  14. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Amico, Francesco

    2011-01-01

    In major depressive disorder (MDD), it is unclear to what extent structural brain changes are associated with depressive episodes or represent part of the mechanism by which the risk for illness is mediated. The aim of this study was to investigate whether structural abnormalities are related to risk for the development of MDD.

  15. The Brothers and Sisters Learn To Write: Popular Literacies in Childhood and School Cultures.

    Science.gov (United States)

    Dyson, Anne Haas

    Building on the author's groundbreaking work in "Building Superheroes," this book traces the influence of a wide-ranging set of "textual toys" from children's lives--church and hip-hop songs, rap music, movies, TV, traditional jump-rope rhymes, the words of professional sports announcers and radio deejays--upon school learning…

  16. Band of Brothers - Warrior Ethos, Unit Effectiveness and the Role of Initial Entry Training

    National Research Council Canada - National Science Library

    Sando, Donald

    2004-01-01

    .... Integral to continued professionalism of the Army is developing cultural attitudes beliefs and behaviors of a Warrior Ethos the culture of disciplined initiative teamwork determination sacrifice...

  17. Band of Brothers or Dysfunctional Family? A Military Perspective on Coalition Challenges During Stability Operations

    Science.gov (United States)

    2011-01-01

    the army, there were lots of examples of NGOs [that] were quite happy on a working level to meet for coffee in Pristina and sit over a map and...coalition units for a visit and found that the units would have the coffee brewing . . . and we’d lay out where we are going . . . and they’d go off and...our obsession with this curious taxonomy, in a world of our own, where we talk about “supporting effects” and “end states”—it just isn’t how these

  18. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Zagozdzon, Agnieszka M

    2012-05-30

    AbstractBackgroundNumerous transgenic models have been generated to study breast cancer. However, despite many advantages, traditional transgenic models for breast cancer are also burdened with difficulties in early detection and longitudinal observation of transgene-induced tumours, which in most cases are randomly located and occur at various time points. Methods such as palpation followed by mechanical measurement of the tumours are of limited value in transgenic models. There is a crucial need for making these previously generated models suitable for modern methods of tumour visualisation and monitoring, e.g. by bioluminescence-based techniques. This approach was successfully used in the current study.ResultsA new mouse strain (MMTV-Luc2 mice) expressing Luc2 luciferase primarily in mammary tissue in females, with low-level background expression in internal organs, was generated and bred to homozygosity. After these mice were intercrossed with MMTV-PyVT mice, all double transgenic females developed mammary tumours by the age of 10 weeks, the localisation and progression of which could be effectively monitored using the luminescence-based in vivo imaging. Luminescence-based readout allowed for early visualisation of the locally overgrown mammary tissue and for longitudinal evaluation of local progression of the tumours. When sampled ex vivo at the age of 10 weeks, all tumours derived from MMTV-Luc2PyVT females displayed robust bioluminescent signal.ConclusionsWe have created a novel transgenic strain for visualisation and longitudinal monitoring of mammary tumour development in transgenic mice as an addition and\\/or a new and more advanced alternative to manual methods. Generation of this mouse strain is vital for making many of the existing mammary tumour transgenic models applicable for in vivo imaging techniques.

  19. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Murphy, E

    2010-04-01

    This paper explores methodological issues and policy implications concerning the implementation of the EU Environmental Noise Directive (END) across Member States. Methodologically, the paper focuses on two key thematic issues relevant to the Directive: (1) calculation methods and (2) mapping methods. For (1), the paper focuses, in particular, on how differing calculation methods influence noise prediction results as well as the value of the EU noise indicator L(den) and its associated implications for comparability of noise data across EU states. With regard to (2), emphasis is placed on identifying the issues affecting strategic noise mapping, estimating population exposure, noise action planning and dissemination of noise mapping results to the general public. The implication of these issues for future environmental noise policy is also examined.

  20. The Driver Whose Heart Was Full of Sand: Leigh's Story--A Play Therapy Case Study of a Bereaved Child

    Science.gov (United States)

    Robson, Maggie

    2008-01-01

    This paper describes the therapeutic journey of Leigh (not his real name), a nine-year-old boy who was referred for play therapy due to the death of his 15-year-old brother. The play therapy was offered through a joint project called "Playing through Loss" and run jointly between a UK university and the local branch of a national…

  1. Interdisciplinary Full Mouth Rehabilitation of a Patient with Amelogenesis Imperfecta: A Case Report with 8 Years Follow-up

    Science.gov (United States)

    Sreedevi, S; Sanjeev, R; Ephraim, Rena; Joseph, Mathai

    2014-01-01

    This case report deals with the interdisciplinary approach of a 28-year-old lady with Amelogenesis imperfecta of the hypoplastic kind. The patient came with a chief illness of worn out teeth, unsatisfactory esthetics and severe sensitivity of teeth. Her family history revealed a related situation in her father’s brother and her sister. On clinical assessment, the crowns of all teeth were worn out. The plan of the treatment was to protect as much tooth structure, restore the vertical dimension, and improve esthetics and masticatory function. The treatment procedures involved prosthodontic, endodontic, and periodontic interventions. After recording the vertical height, endodontic treatment and crown lengthening were performed with respect to the lower anteriors. The lost vertical height was regained in stages by insertion of full coverage crowns for all the teeth. The patient’s esthetic and functional needs were met with systematic and sequential interdisciplinary treatment approach. PMID:25628493

  2. Big Brother is watching but helping you : analyse et interprétation de mouvements humains (expressions, gestes, postures) : Big Brother is watching but helping you : human motion analysis and interpretation

    OpenAIRE

    Caplier , Alice

    2005-01-01

    Mes activités de recherche portent sur l'analyse et l'interprétation des mouvements humains à partir de données visuelles avec comme application principale l'amélioration du processus de communication entre l'homme et la machine. L'idée sous-jacente est de tendre vers une communication homme machine non pas par l'intermédiaire des traditionnels écran/clavier/souris mais vers un processus plus « humain » de communication. Ceci suppose que la machine est capable de reconnaître et d'interpréter ...

  3. Intralocus sexual conflict in humans: Physically and hormonally masculine individuals have more attractive brothers relative to sisters

    NARCIS (Netherlands)

    Garver-Apgar, C.E; Heap, G.A.; Tybur, J.M.; Emery-Thompson, M.

    2011-01-01

    Intralocus sexual conflict (IASC) occurs when sex-specific selection favors genes that increase fitness in one sex and decrease fitness in the other sex. The current study was designed to explore whether IASC occurs in humans. In a sample of siblings, we identified and measured sexually dimorphic

  4. My Brother's Keeper: Nurturing In-School Relationships for Young Men of Color in New York City

    Science.gov (United States)

    Forbes, Paul; Klevan, Sarah

    2018-01-01

    Black and Latino men pay a heavy price for the structural inequities they face, such as higher rates of poverty, incarceration, and unemployment. New York City's Young Men's Initiative, a combination of new programs and policy reforms, seeks to mitigate some of the effects of these inequitable conditions on young men of color. The educational…

  5. The Antebellum American Textbook Authors' Populist History of Roman Land Reform and the Gracchi Brothers

    Science.gov (United States)

    McInnis, Edward

    2015-01-01

    This essay explores social and political values conveyed by nineteenth century world and universal history textbooks in relation to the antebellum era. These textbooks focused on the histories of ancient Greece and Rome rather than on histories of the United States. I argue that after 1830 these textbooks reinforced both the US land reform and the…

  6. My Best Friend's Brother's Cousin Knew This Guy Who?…?: Hoaxes, Legends, Warnings, and Fisher's Narrative Paradigm

    Science.gov (United States)

    Hobart, Melissa

    2013-01-01

    Students frequently encounter stories in the form of urban legends but often fail to analyze them properly. Using urban legends to teach is often a lively and informative method, and deconstructing common persuasive messages can show students the applicability of theory to real life. The author states that her goal as a teacher is to help students…

  7. Lehman Brothers in the Dutch offshore financial centre: The role of shadow banking in increasing leverage and facilitating debt

    NARCIS (Netherlands)

    Fernandez, R.; Wigger, A.

    2016-01-01

    Credit intermediation outside the regular banking system, or shadow banking, has increased immensely over the past decade. This paper situates this increase against the backdrop of the structural problem of overaccumulation, and thus the absence of profitable reinvestment opportunities in the

  8. Who has demanded this plate? the history of meson mu o muon, the fat brother of the electron

    International Nuclear Information System (INIS)

    Boya, L.J.

    1997-01-01

    We retrace the discovery of the muon and stress its importance in the establishment of the standard model in particle physics. We remark the necessity of the existence of three families. At the end we speculate on some recent issues. (Author) 12 refs

  9. Briley Brothers: The Influence of Birth Order, Sibling Relationship Quality and the Normalization of Violence on Adolescent Delinquency

    OpenAIRE

    Morales, Denixa; Esparza, Joshua; Kaur, Manjinder

    2017-01-01

    This literature review examines different factors that influence adolescent delinquency such as sibling relationship quality, birth order, and normalization of violence. The review uses a psychosocial approach to observe how these factors can affect an adolescent’s behavior. This research will contribute to the field of Psychology by emphasizing that outcomes associated with adolescent delinquency can be traced to specific points. The main points of this research are further supported by the ...

  10. The Impact of Siblings with Disabilities on Their Brothers and Sisters Pursuing a Career in Special Education

    Science.gov (United States)

    Marks, Susan Unok; Matson, Amy; Barraza, Lori

    2005-01-01

    It is well known that growing up with a sibling who has a disability has both positive and negative impacts on the non-disabled sibling (Beckman, 2002; Fisman, Wolf, Ellison, & Freeman, 2000; Gans, 1997; McHugh, 2003). In fact, the concern for ameliorating the potential negative impacts on nondisabled siblings has been a major impetus for the…

  11. "When the obvious brother is not there": political and cultural contexts of the orphan challenge in northern Uganda.

    Science.gov (United States)

    Oleke, Christopher; Blystad, Astrid; Rekdal, Ole Bjørn

    2005-12-01

    It is estimated that two million of Uganda's children today are orphaned primarily due to AIDS. While recognising the immense impact of HIV/AIDS on the present orphan problem, this article calls for a broader historic and cultural contextualisation to reach an understanding of the vastness of the orphan challenge. The study on which the article is based was carried out among the Langi in Lira District, northern Uganda, with a prime focus on the situation of orphans within the extended family system. The data were collected through ethnographic fieldwork (8 months); in-depth interviews with community leaders (21), heads of households (45) and orphans (35); through focus group discussions (5) with adult men and women caring for orphans, community leaders and with orphans; and also through documentary review. A survey was conducted in 402 households. The findings reveal a transition over the past 30 years from a situation dominated by 'purposeful' voluntary exchange of non-orphaned children to one dominated by 'crisis fostering' of orphans. Sixty-three percent of the households caring for orphans were found to be no longer headed by resourceful paternal kin in a manner deemed culturally appropriate by the patrilineal Langi society, but rather by marginalised widows, grandmothers or other single women receiving little support from the paternal clan. This transition is partly linked to an abrupt discontinuation of the Langi 'widow inheritance' (laku) practice. It is argued that the consequential transformations in fostering practices in northern Uganda must be historically situated through a focus on the effects of armed conflicts and uprooting of the local pastoral and cotton-based economy, which have occurred since the late 1970s. These processes jointly produced dramatic economic marginalisation with highly disturbing consequences for orphans and their caretakers.

  12. Is Big Brother Watching You? The Evolving Role of the State in Regulating and Conducting Quality Assurance. CIQG Publication Series

    Science.gov (United States)

    Salmi, Jamil

    2015-01-01

    A recent report published in the United Kingdom proposed the image of "an avalanche" to describe the radical changes affecting tertiary education in many parts of the world (Barber, Donnelly and Rizvi, 2013). Indeed, powerful transformative forces of three kinds--rupture factors, crisis factors and stimulus factors--are challenging…

  13. "Brothers Gonna Work It Out:" Understanding the Pedagogic Performance of African American Male Teachers Working with African American Male Students

    Science.gov (United States)

    Brown, Anthony L.

    2009-01-01

    Drawing from ethnographic data, this paper explores how African American male teachers working with African American male students performed their pedagogy. This paper highlights how teachers' understanding of African American males social and educational needs shaped their pedagogical performance. Interestingly however, teachers' performance was…

  14. Why Can't I Be More Like My Brother? The Role and Correlates of Sibling Social Comparison Orientation.

    Science.gov (United States)

    Jensen, Alexander C; Pond, Amanda M; Padilla-Walker, Laura M

    2015-11-01

    Siblings play an important role in relational and individual development throughout adolescence and beyond through several mechanisms. Central to this role and the mechanisms of sibling influence is the notion that siblings provide a constant and meaningful frame of reference for social comparison. This study examined the role of sibling social comparison orientation, or the tendency of siblings to compare themselves to one another, on youths' depressive symptoms and family relationships, both directly and by moderating links with parental differential treatment. Participants included 338 youth (M age = 18.34, SD = 1.03; 52 % female). Using hierarchical ordinary least squares regression, we found that a higher sibling social comparison orientation was linked with more depressive symptoms, warmer sibling relationships, and more sibling conflict. Additionally, sibling social comparison orientation moderated links of parental differential treatment with depressive symptoms and prosocial behavior toward family members such that effects were more salient for those with a high comparison orientation. The discussion focuses on the role of sibling comparison in the ways that siblings influence one another's development.

  15. Radiological survey of the former Baker Brothers, Inc. site, 2551--2555 Harleau Place, Toledo, Ohio (BTO001)

    International Nuclear Information System (INIS)

    Foley, R.D.; Floyd, L.M.

    1992-03-01

    At the request of the US Department of Energy (DOE), a team from Oak Ridge National Laboratory conducted investigative radiological surveys at the REMS, Inc., and the Doug Beet Company, 2551-2555 Harleau Place, Toledo, Ohio (BTO001) in 1988. The purpose of the surveys was to determine whether the property was contaminated with radioactive residues, principally 238 U, as a result of work contracted to the Manhattan Engineer District (MED). The survey included gamma scans; directly measured alpha, beta, and gamma radiation levels; transferable contamination levels; and soil, dust, debris, and air sampling for radionuclide analyses. The survey and sampling covered accessible portions of the exterior ground surface, roof, and interiors of buildings. Results of the surveys demonstrated four general areas having radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria for 238 U outdoors and as surface contamination on shelves in one building

  16. Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project.

    Science.gov (United States)

    Redfern, William S; Tse, Karen; Grant, Claire; Keerie, Amy; Simpson, David J; Pedersen, John C; Rimmer, Victoria; Leslie, Lauren; Klein, Stephanie K; Karp, Natasha A; Sillito, Rowland; Chartsias, Agis; Lukins, Tim; Heward, James; Vickers, Catherine; Chapman, Kathryn; Armstrong, J Douglas

    2017-01-01

    Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing. We have used a subcutaneous radiofrequency identification (RFID) transponder to measure ambulatory activity and temperature of individual rats when group-housed in conventional, rack-mounted home cages. The transponder location and temperature is detected by a matrix of antennae in a baseplate under the cage. An infrared high-definition camera acquires side-view video of the cage and also enables automated detection of vertical activity. Validation studies showed that baseplate-derived ambulatory activity correlated well with manual tracking and with side-view whole-cage video pixel movement. This technology enables individual behavioral and temperature data to be acquired continuously from group-housed rats in their familiar, home cage environment. We demonstrate its ability to reliably detect naturally occurring behavioral effects, extending beyond the capabilities of routine observational tests and conventional monitoring equipment. It has numerous potential applications including safety pharmacology, toxicology, circadian biology, disease models and drug discovery.

  17. Agents of the Father's law in a society of brothers: A philosophic and psychoanalytic perspective on legitimate use of violence.

    Science.gov (United States)

    Even-Tzur, Efrat; Hadar, Uri

    This paper explores subjective processes of "Agents of Law" - individuals who the state grants the authority to use violence - and the dissonance stemming from the contradictory demands posed on them as legitimate users of violence despite the societal taboo against violence. A conceptual model will be offered based on two theoretical legs, Lacanian psychoanalysis and political theories of legitimacy. Specifically, psychoanalytic ideas would serve to examine unconscious processes, subject position and various identifications related to the question of "self-legitimacy" of Agents of Law. A central link between psychoanalysis and political thought is found in the image of the father and in the triad ruler-God-Father, which calls for an oedipal analysis. A psychoanalytic reading of two philosophical schools that elaborated on the question of legitimacy will be presented, and yield two analytic poles of a model for the understanding of possible subject positions of agents of Law: identification with a "Living Father" vs. identification with a "Dead Father". The psychoanalytic reading will shed light on the limitations of the philosophical perspectives in reflecting on the various (im)possible psychological positions of agents of Law. Finally, then, it will be shown how psychoanalysis helps finding words to characterize different nuances in the coping of agents of Law with the contradictory demands posed on them in an age in which God is dead, the father was murdered and the king was beheaded. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Early 20th Century Education in the United States: The Role of the Brothers of Holy Cross

    Science.gov (United States)

    Armstrong, Philip C.

    2007-01-01

    The French Revolution bears an ironic responsibility for generating works of charity. To counteract the devastating social effects of that late 18th century uprising, numerous religious communities were founded in France, among them the Congregation of Holy Cross. The Congregation of Holy Cross, the founding religious community behind the…

  19. From Napoleon Conquests to the Big Brother Sabotage : Harmonization of the Dutch Historical Censuses in the Semantic Web

    NARCIS (Netherlands)

    Meroño-Peñuela, Albert; Ashkpour, Ashkan

    2014-01-01

    Around the turn of the 18th century, the first integral pop- ulation enumeration was held in the Netherlands during the Batavian Republic. It took over 30 years before the first official census was, by royal decree, organized and conducted in 1829, and was meant to be held from then onwards every

  20. 75 FR 16903 - Public Notice for Waiver of Aeronautical Land-Use Assurance Dayton-Wright Brothers Airport...

    Science.gov (United States)

    2010-04-02

    ... accordance with FAA's Policy and Procedures Concerning the Use of Airport Revenue, published in the Federal... notice is required to be published in the Federal Register 30 days before modifying the land-use... Centerline of Construction of Austin Boulevard, as shown on Plat Book 212, Pages 34 and 34A as surveyed by...

  1. Ehlers danlos syndrome in two siblings

    Directory of Open Access Journals (Sweden)

    Das M

    2005-01-01

    Full Text Available Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.

  2. AcEST: BP916278 [AcEST

    Lifescience Database Archive (English)

    Full Text Available DROER GG24967 OS=Drosophila erecta GN=GG24967 P... 33 9.2 tr|A4V047|A4V047_DROME Brother of odd with entrails...SFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails

  3. AcEST: BP915933 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 9.1 tr|A4V047|A4V047_DROME Brother of odd with entrails limited, iso... 33 9.1 >tr|B4L9X7|B4L9X7_DROMO GI141...IITQPESGKPPNQPLHSPHEAMPSFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails

  4. Do Brothers Affect Their Sisters' Chances to Graduate? An Analysis of Sibling Sex Composition Effects on Graduation from a University or a "Fachhochschule" in Germany

    Science.gov (United States)

    Jacob, Marita

    2011-01-01

    In a recent paper on gender inequality in higher education Buchman and DiPrete (2006) assume that the decrease in the gender gap in college completion in the US can partly be explained by changes in the allocation of familial resources in favour of women. However, they do not test this hypothesis empirically. In this paper I examine the effects of…

  5. 'He is now like a brother, I can even give him some blood'--relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia.

    Science.gov (United States)

    Geissler, P Wenzel; Kelly, Ann; Imoukhuede, Babatunde; Pool, Robert

    2008-09-01

    This paper explores social relations within the 'trial community' (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, we explore processes of mediation between scientific project and study population, and between formal ethics, local ethical debates and everyday practice. We observe that material contact and substantial transactions, notably of blood and medicine, are central to the construction of the MVT. These transactions are guided by a concrete and relational form of ethics, which contrasts with the abstract and vertical formal ethical principles underwriting the scientific study protocol. The success of the MVT owed much to these kinship-like ethics. One possible conclusion from these observations is that research ethics should be understood, not just as a quasi-legal frame but also as an open, searching movement, much in the same way that kinship is not merely a juridical institution and a prescriptive frame of rules, but a network made through relational work. However, this conclusion raises new problems: by contrasting formal, abstract principles to intimate, immediate relations, and economic justice to personal morality, we accept that the order of medical research is moved further out of the public and political, and into the domains of either quasi-legal claims or of private morality. Irrespective of the undeniable importance of clear-cut rules and of good face-to-face relations, a third essential foundation of medical research ethics is the democratically constituted public sphere, including equitable health services, and transparent institutions to facilitate open debate and regulate particular interests. Ultimately, the ethics of global science can rely neither on principles nor trust but requires citizenship and democratic government.

  6. "When He's around His Brothers ... He's Not so Quiet": The Private and Public Worlds of School-Aged Children with Speech Sound Disorder

    Science.gov (United States)

    McLeod, Sharynne; Daniel, Graham; Barr, Jacqueline

    2013-01-01

    Children interact with people in context: including home, school, and in the community. Understanding children's relationships within context is important for supporting children's development. Using child-friendly methodologies, the purpose of this research was to understand the lives of children with speech sound disorder (SSD) in context.…

  7. 'A band of brothers'-an exploration of the range of medical ethical issues faced by British senior military clinicians on deployment to Afghanistan: a qualitative study.

    Science.gov (United States)

    Bernthal, Elizabeth M; Draper, H J A; Henning, J; Kelly, J C

    2017-06-01

    To identify and explore features of ethical issues that senior clinicians faced as deployed medical directors (DMDs) to the British Field Hospital in Afghanistan as well as to determine the ethical training requirements for future deployments. A qualitative study in two phases conducted from November 2014 to June 2015. Phase 1 analysed 60 vignettes of cases that had generated ethical dilemmas for DMDs. Phase 2 included focus groups and an interview with 13 DMDs. Phase 1 identified working with limited resources, dual conflict of meeting both clinical and military obligations and consent of children as the most prevalent ethical challenges. Themes found in Phase 2 included sharing clinical responsibilities with clinicians from other countries and not knowing team members' ways of working, in addition to the themes from Phase 1. This study has drawn together examples of scenarios to form a repository that will aid future training. Recommendations included undertaking ethics training together as a team before, during and after deployment which must include all nationalities who are assigned to the same operational tour, so that different ethical views can be explored beforehand. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections

    OpenAIRE

    Xu, Xiu; Xu, Qiong; Zhang, Ying; Zhang, Xiaodi; Cheng, Tianlin; Wu, Bingbing; Ding, Yanhua; Lu, Ping; Zheng, Jingjing; Zhang, Min; Qiu, Zilong; Yu, Xiang

    2012-01-01

    Abstract Background Autistic spectrum disorders (ASDs) are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Case presentation Here, we identified a Chinese famil...

  9. Increased expression of brother of the regulator of imprinted sites in peripheral blood neutrophils is associated with both benign and malignant breast lesions.

    Science.gov (United States)

    El-Sharkawy, Nahla M; Radwan, Wafaa M; Essa, Enas S; Kandeel, Eman Z; Abd El-Fattah, Eman K; Kandil, Samia H; Kamel, Azza M

    2017-09-01

    BORIS, a paralog of the multifunctional CCCTC-binding factor (CTCF) gene is restricted to testis and normally not present in females. It is aberrantly activated in various human cancers including cancer breast. Using immunohistochemistry, western blot and/or RT-PCR, significantly higher levels of BORIS expression were reported in the neutrophils of cancer breast patients. We hypothesized that Flow Cytometry might be a better technique for objective quantitative evaluation of BORIS in neutrophils and we wanted to investigate if BORIS would discriminate between benign and malignant breast lesions. The study included 85 females; 52 breast cancer, 13 benign breast lesions and 20 age-matched healthy controls. BORIS expression in the neutrophils was detected by Flow Cytometry. High level of BORIS was detected in all malignant (64.4 ± 16.6%) and benign cases (67 ± 12.3), mean florescent intensity ratio (MFIR) of 7.2 ± 4.1 and 7 ± 3.5, median 5.8 and 6.6%; and staining index (SI) 8.3 ± 3.9 and 8.2 ± 3.4, median 7.6 and 7.9 respectively vs.13.4 ± 11.5% MFI 1.8 ± 0.7, median1.6 and SI 2.6 ± 0.69, median 2.5 for the control. BORIS level was comparable in the malignant and benign group (P = 0.934) and significantly higher than control (P = 0.0001). There was no correlation between neutrophil BORIS expression and ER/PR status, HER-2/neu expression or tumor stage or size. Increased BORIS expression in peripheral blood neutrophils is associated with both benign and malignant breast lesions; apparently, increased proliferation of breast tissue is the determining factor. This excludes BORIS as a tumor marker but it does not jeopardize its value as a potential therapeutic target. © 2016 International Clinical Cytometry Society. © 2016 International Clinical Cytometry Society.

  10. Deletion of UBE3A in brothers with Angelman syndrome at the breakpoint with an inversion at 15q11.2.

    Science.gov (United States)

    Kuroda, Yukiko; Ohashi, Ikuko; Saito, Toshiyuki; Nagai, Jun-Ichi; Ida, Kazumi; Naruto, Takuya; Wada, Takahito; Kurosawa, Kenji

    2014-11-01

    Angelman syndrome (AS) is characterized by severe intellectual disability with ataxia, epilepsy, and behavioral uniqueness. The underlining molecular deficit is the absence of the maternal copy of the imprinted UBE3A gene due to maternal deletions, which is observed in 70-75% of cases, and can be detected using fluorescent in situ hybridization (FISH) of the UBE3A region. Only a few familial AS cases have been reported with a complete deletion of UBE3A. Here, we report on siblings with AS caused by a microdeletion of 15q11.2-q12 encompassing UBE3A at the breakpoint of an inversion at 15q11.2 and 15q26.1. Karyotyping revealed an inversion of 15q, and FISH revealed the deletion of the UBE3A region. Array comparative genomic hybridization (CGH) demonstrated a 467 kb deletion at 15q11.2-q12, encompassing only UBE3A, SNORD115, and PAR1, and a 53 kb deletion at 15q26.1, encompassing a part of SLCO3A1. Their mother had a normal karyotype and array CGH detected no deletion of 15q11.2-q12, so we assumed gonadal mosaicism. This report describes a rare type of familial AS detected using the D15S10 FISH test. © 2014 Wiley Periodicals, Inc.

  11. The Knight Brothers from the Low Countries in the Conflict between the Westphalians and the Rhinelanders in the Livonian Branch of the Teutonic Order

    NARCIS (Netherlands)

    Mol, J.A.

    2016-01-01

    In the fifeenth century the Livonian branch of the Teutonic Order was internally divided by a long-lasting conflict between two groups of knight brethren, the Westphalians and the Rhinelanders, who were united according to regional origin. They each strived to control the most important offces,

  12. Big brother is watching you--the ethical implications of electronic surveillance measures in the elderly with dementia and in adults with learning difficulties.

    Science.gov (United States)

    Welsh, S; Hassiotis, A; O'Mahoney, G; Deahl, M

    2003-09-01

    Electronic surveillance has insidiously seeped into the fabric of society with little public debate about its moral implications. Perceived by some as a sinister Orwellian tool of repression and social control, the new technologies offer comfort and security to others; a benevolent parental watchful eye. Nervousness at being watched has been replaced increasingly by nervousness if we're not. These technologies are now becoming widely available to health care professionals who have had little opportunity to consider their ethical and moral ramifications. Electronic tagging and tracking devices may be seen as away of creating a more secure environment for vulnerable individuals such as the elderly with dementia or people with learning disabilities. However, the proponents of surveillance devices have met with considerable resistance and opposition,from those who perceive it as contrary to human dignity and freedom, with its connotations of criminal surveillance. In addition, they cite increased opportunity for abuse through, for example, the withdrawal of staff and financial resources from the care of people with complex needs. Implementing these technologies, therefore, has ethical implications for human rights and civil liberties. Optional alternatives to long-term and/or restrictive care, in the context of the practical difficulties involved in caring for those who represent a risk to themselves from wandering, demands rigorous exploration of pragmatic questions of morality, with reference to risk versus benefit strategies. Like reproductive cloning techniques, the mere existence of surveillance technologies is morally neutral. Rather it is the use (in this instance that of health and social care settings) to which it is put which has the potential for good or bad.

  13. Family Characteristics and Achievement: Effects of Birth Order and Family Size of the Kalamazoo Brothers Sample. Discussion Papers No. 431-77.

    Science.gov (United States)

    Olneck, Michael R.; Bills, David B.

    Research on the effects of birth order on cognitive ability often fails to control relevant variables related to family background and does not usually investigate the effects of birth order among members of the same family. Consequently, apparently significant birth order effects may in fact be spurious. This study uses a sample of brothers…

  14. "When he's around his brothers … he's not so quiet": the private and public worlds of school-aged children with speech sound disorder.

    Science.gov (United States)

    McLeod, Sharynne; Daniel, Graham; Barr, Jacqueline

    2013-01-01

    Children interact with people in context: including home, school, and in the community. Understanding children's relationships within context is important for supporting children's development. Using child-friendly methodologies, the purpose of this research was to understand the lives of children with speech sound disorder (SSD) in context. Thirty-four interviews were undertaken with six school-aged children identified with SSD, and their siblings, friends, parents, grandparents, and teachers. Interview transcripts, questionnaires, and children's drawings were analyzed to reveal that these children experienced the world in context dependent ways (private vs. public worlds). Family and close friends typically provided a safe, supportive environment where children could be themselves and participate in typical childhoods. In contrast, when out of these familiar contexts, the children often were frustrated, embarrassed, and withdrawn, their relationships changed, and they were unable to get their message across in public contexts. Speech-language pathology assessment and intervention could be enhanced by interweaving the valuable insights of children, siblings, friends, parents, teachers, and other adults within children's worlds to more effectively support these children in context. 1. Recognize that children with SSD experience the world in different ways, depending on whether they are in private or public contexts. 2. Describe the changes in the roles of family and friends when children with SSD are in public contexts. 3. Discover the position of the child as central in Bronfenbrenner’s bioecological model. 4. Identify principles of child-friendly research. 5. Recognize the importance of considering the child in context during speech-language pathology assessment and intervention. Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

  15. Hepatic Encephalopathy

    Medline Plus

    Full Text Available ... to continue to work to my full capacity? Will I be able to drive? Patient Stories Angie M. Caregiver for Brother Charles DiAngelo Hepatic Encephalopathy Jason Dedmon Alcohol-related Cirrhosis ...

  16. Visual hallucinations caused by Charles Bonnet Syndrome: A case ...

    African Journals Online (AJOL)

    had no cognitive impairment and was fully aware of the ... eration. Ms P's main complaint was visual hallucinations. ... brother in front of her eyes. She also displayed ... her would seem to develop a full beard. .... Beta blocking agents. 4.

  17. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Recently posted: How to Obtain and Share Your Medical Images Movement Disorders Video: The Basketball Game: An ... oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk Grove Village, Illinois. I’d ...

  18. Experience of Linguo-rhetoric Approach Realization in the Process of Classical Writer Literal Personality Idiodiscourse

    Directory of Open Access Journals (Sweden)

    Vladlena V. Siganova

    2012-05-01

    Full Text Available The article characterizes major results of integrated linguo-rhetoric approach application to writer’s idiodiscourse (F.M. Dostoevsky’s ‘The Brothers Karamazov’ case study.

  19. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... library Topic Type Living Alone: Home Safety and Management in PD Expert Briefings: Marijuana and PD: What ... a Brother: Donna’s Story OHSU - Parkinson's Disease: Pharmacological Management of Depression, Anxiety & Psychosis What Are Some Strategies ...

  20. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Site Index A-Z Spotlight Recently posted: Pancreatic Cancer The Limitations of Online Dose Calculators Video: The ... Dr. Ramji Rajendran, a radiation oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk ...

  1. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... June is Men's Health Month Recently posted: Pancreatic Cancer The Limitations of Online Dose Calculators Video: The ... Dr. Ramji Rajendran, a radiation oncologist at the Cancer Institute at Alexian Brothers Medical Center in Elk ...

  2. The LHC experiment control system: on the path to full automation

    International Nuclear Information System (INIS)

    Gaspar, C.; Alessio, F.; Cardoso, L.; Frank, M.; Garnier, J.C.; Herwijnen, E.V.; Jacobsson, R.; Jost, B.; Neufeld, N.; Schwemmer, R.; Callot, O.; Franek, B.

    2012-01-01

    LHCb is a large experiment at the LHC accelerator. The experiment control system is in charge of the configuration, control and monitoring of the different sub-detectors and of all areas of the online system. The building blocks of the control system are based on the PVSS SCADA System complemented by a control Framework developed in common for the 4 LHC experiments. This framework includes an 'expert system' like tool called SMI++ which is used for the system automation. The experiment's operations are now almost completely automated, driven by a top-level object called Big-Brother, which pilots all the experiment's standard procedures and the most common error-recovery procedures. The architecture, tools and mechanisms used for the implementation as well as some operational examples will be described. (authors)

  3. The Nigrescence of the "Okay" Brother: a Phenomenological Study on the Impact of an Education in a Traditionally White Learning Institution on the Racial Identity Development of Black Males in Professional Careers

    Science.gov (United States)

    Edwards, Hayley E.

    2012-01-01

    There are many stereotypes of the Black male that have been portrayed in the media through news stories, film, and television. They are often portrayed as shiftless, lazy, violent, or subservient, or praised for their athletic prowess, their music, or their value as entertainers. Occasionally, Black men are portrayed as the lone person of color…

  4. Big brother is watching you : le rôle des technologies de l'information dans la stratégie de contrôle des réseaux de points de vente franchisés

    OpenAIRE

    Kalika, Michel; Boulay, Jacques

    2007-01-01

    Based on a study conducted in the setting of French franchise networks (sample: 428 franchisees), this research establishes the existence of a channel technological control that operates through a « panoptic effect ». The results suggest that information technologies have the capacity to support a more efficient channel control strategy.

  5. "I Am Becoming More and More Like My Eldest Brother!": The Relationship Between Older Siblings, Adolescent Gambling Severity, and the Attenuating Role of Parents in a Large-Scale Nationally Representative Survey Study.

    Science.gov (United States)

    Canale, Natale; Vieno, Alessio; Griffiths, Mark D; Siciliano, Valeria; Cutilli, Arianna; Molinaro, Sabrina

    2017-06-01

    The present study examined the association between having older siblings who gamble and adolescent at-risk/problem gambling and how parents (i.e., parental knowledge of their whereabouts) and peers might moderate such effects. Data were drawn from the ESPAD ® Italia2012 survey (European School Survey Project on Alcohol and Other Drugs) comprising a nationally representative Italian sample of adolescents. The analysis was carried out on a subsample of 10,063 Italian students aged 15-19 years (average age = 17.10; 55 % girls) who had at least one older sibling and who had gambled at some point in their lives. Respondents' problem gambling severity, older gambler sibling, gambler peers, parental knowledge, and socio-demographic characteristics were individually assessed. Multinomial logistic regression analyses including two- and three-way interactions were conducted. The odds of being an at-risk/problem gambler were higher among high school students with older siblings that gambled and those with peers who gambled. Higher parental knowledge (of who the adolescent was with and where they were in their leisure time) was associated with lower rates of at-risk/problem gambling. There was also an interaction between gamblers with older siblings and parental knowledge. The combination of having siblings who gambled and a greater level of parental knowledge was associated with lower levels of problem gambling. The present study confirmed the occurrence of social risk processes (older siblings and peers who gambled) and demonstrated that gambling among older siblings and peers represents an important contextual factor for increased at-risk/problem gambling. However, parental knowledge appears to be sufficient to counterbalance the influence of older siblings.

  6. "I Will Tell You about Playing with My Brother, but Not about His Autism": Perceptions of Social Interaction from the Voice of Child Who Has a Sibling Identified with Autism Spectrum Disorder

    Science.gov (United States)

    Papacek, Amy M.

    2012-01-01

    Autism Spectrum Disorder (ASD) is experienced in a variety of ways within families particularly among siblings with and without ASD. The effects of ASD on sibling relationships are integral to family life. While some studies have examined sibling relationships, research regarding sibling roles exhibited during play activities and social…

  7. Towards a personalized Internet: a case for a full decentralization.

    Science.gov (United States)

    Kermarrec, Anne-Marie

    2013-03-28

    The Web has become a user-centric platform where users post, share, annotate, comment and forward content be it text, videos, pictures, URLs, etc. This social dimension creates tremendous new opportunities for information exchange over the Internet, as exemplified by the surprising and exponential growth of social networks and collaborative platforms. Yet, niche content is sometimes difficult to retrieve using traditional search engines because they target the mass rather than the individual. Likewise, relieving users from useless notification is tricky in a world where there is so much information and so little of interest for each and every one of us. We argue that ultra-specific content could be retrieved and disseminated should search and notification be personalized to fit this new setting. We also argue that users' interests should be implicitly captured by the system rather than relying on explicit classifications simply because the world is by nature unstructured, dynamic and users do not want to be hampered in their actions by a tight and static framework. In this paper, we review some existing personalization approaches, most of which are centralized. We then advocate the need for fully decentralized systems because personalization raises two main issues. Firstly, personalization requires information to be stored and maintained at a user granularity which can significantly hurt the scalability of a centralized solution. Secondly, at a time when the 'big brother is watching you' attitude is prominent, users may be more and more reluctant to give away their personal data to the few large companies that can afford such personalization. We start by showing how to achieve personalization in decentralized systems and conclude with the research agenda ahead.

  8. Preparing Your Child for a New Sibling (For Parents)

    Science.gov (United States)

    ... Family Getting Along With Brothers and Sisters Kids Talk About: Brothers and Sisters View more ... All information on KidsHealth® is for educational purposes only. For specific medical advice, diagnoses, and ...

  9. South African Journal of Philosophy - Vol 32, No 1 (2013)

    African Journals Online (AJOL)

    Am I My Brother's Keeper? On Personal Identity and Responsibility · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ... Is the Choice on Termination of Pregnancy Act Guilty of Disability Discrimination? EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Hall, 36-46.

  10. The Role of Family Background for Earnings in Rural China

    DEFF Research Database (Denmark)

    Eriksson, Tor Viking; Qiang, Zhang Ying

    This paper provides estimates of brother income correlations for rural China. Brother correlations are a parsimonious measure of the importance of family and community background as determinants of individuals' economic status. We find internationally high levels of income similarity for brothers...

  11. An unusual occurrence of repeated single allele variation on Y-STR locus DYS458

    Directory of Open Access Journals (Sweden)

    Pankaj Shrivastava

    2016-09-01

    Full Text Available Six brothers were accused of gagging and raping a woman. A single male Y-STR profile was obtained from vaginal smear swab and clothes of the victim, which did not match with the DNA profile of the accused brothers. As a reference point, the blood sample of their father (aged 87 years was also analyzed with the same kit. The Y-STR haplotype of all six brothers was found to be the same as that of their father except at locus DYS458. At this locus, while the eldest, second and fourth siblings share allele 18 with their father, a loss of one repeat (allele 17 instead of 18 is observed in the third son while fifth and sixth siblings have allele 19 representing a gain of one repeat. Thus, two changes viz. a gain (twice and loss of one repeat at this locus in one generation is both interesting and unusual.

  12. The Idea of Dialogue, Trust and Reconciliation in the Pilgrimage of Trust on Earth

    Directory of Open Access Journals (Sweden)

    Katarzyńska Agnieszka

    2016-12-01

    Full Text Available The purpose of this article is to present the Pilgrimage of Trust on Earth organized by the brothers of Taizé Community as an event building a relationship of dialogue, trust and reconciliation between nations and cultures. The article features an in-depth discussion of the elements of youth meetings and their impact on developing an attitude of dialogue and trust. We will briefly discuss the means used by the brothers to develop a dialogue between people, as well as the methods of spreading the idea of dialogue, trust and solidarity in interpersonal and international relations.

  13. Lady Mary Sidney Herbert a Lady Mary Wroth: labutí píseň a imaginativní svět jako součást rodinného odkazu (Lady Mary Sidney Herbert and Lady Mary Wroth: a Swan song and Fictional World as a part of Sidneyan legacy

    Directory of Open Access Journals (Sweden)

    Martina Kastnerová

    2017-03-01

    Full Text Available The study intends to clarify the process of forming of Sidneyan literary cult as a part of (Sidneyʼs family legacy based on the the literary activities of Sidneyʼs sister Lady Mary Sidney Herbert, countess of Pembroke, and his niece Lady Mary Wroth, daughter of his younger brother Robert. Mary Sidney Herbert throughout her literary career sings a swan song of her brother, Mary Wroth creates an imaginative world of free love choice and happy endings and her literary career is based on the well-established cult of Sidneyʼs name.

  14. AcEST: BP918513 [AcEST

    Lifescience Database Archive (English)

    Full Text Available EAMPSFLGSIPMRKRILPAPTLDLMDPHHHP 673 >tr|A4V047|A4V047_DROME Brother of odd with entrails limited, isoform B ...E Brother of odd with entrails limited, iso... 33 9.9 >tr|B4L9X7|B4L9X7_DROMO GI14159 OS=Drosophila mojavens...8_DROER GG24967 OS=Drosophila erecta GN=GG24967 P... 33 9.9 tr|A4V047|A4V047_DROM

  15. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... Memorial Medicinal: “Terapia fisica para el Parkinson” CareMAP: Thinking Changes: Part 2 Why Dance for PD? CareMAP: ... a Father and a Brother: Donna’s Story CareMAP: Thinking Changes: Part 1 Aware in Care: Real Stories ...

  16. Disseminated Soft Tissue Infection and Sepsis with Stenotrophomonas maltophilia in a Bone Marrow Transplant Patient

    Directory of Open Access Journals (Sweden)

    Jeffrey H Lipton

    1996-01-01

    Full Text Available A 32-year-old female presented with aplastic anemia and subsequently underwent a one-antigen mismatched bone marrow transplant from her brother. She failed to engraft and a second graft was attempted. Protracted neutropenia of three months’ duration despite the use of broad spectrum antibiotics occurred. Stenotrophomonas (Xanthomonas maltophilia metastatic cellulitis developed that did not respond to appropriate antibiotics.

  17. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... PTA, NPF - National Parkinson Foundation CareMAP: Managing Caregiver Stress CareMAP: End-of-Life Care CareMAP: Thinking Changes: ... a Brother: Donna’s Story OHSU - Parkinson's Disease: Pharmacological Management of Depression, Anxiety & Psychosis What Are Some Strategies ...

  18. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... With Non-Parkinson's Disease Medications? Walking for a Father and a Brother: Donna’s Story CareMAP: Life Beyond ... DBS Surgery? NPF Caregiver Summit 2016: Tools For Family Caregivers: Caremap and Caring & Coping CareMAP: Managing Caregiver ...

  19. The important semiotic indicators of Dostoyevsky's emotional image

    Directory of Open Access Journals (Sweden)

    Iskhakova Z.Z.

    2016-12-01

    Full Text Available This article is devoted to finding the emotional semiotic character of F. Dostoevsky that is expressed by the key characters' behaviour in 'The Gambler', 'Idiot', The Brothers Karamazov'. The object of the study is emotionally painted speeches of characters in his works. The subject of the study is emotive signs indices in emotional texts of Fyodor Dostoevsky.

  20. Wien unter Ferdinand I. 1521–1564. Über die Verflechtungen von Fürst, Stadt und Residenz aus kunsthistorischer Perspektive / Vienna under Ferdinand I, 1521-1564. Relations between the prince, the town and the residence from the perspective of art history

    Directory of Open Access Journals (Sweden)

    Renate Holzschuh-Hofer

    2015-12-01

    Full Text Available Driven by his political ambition to obtain the imperial title following his brother Charles V as well as being under the Ottoman threat, Ferdinand I had advocated Vienna’s establishment as the residential capital since 1522. The architecture of his main residence, the Vienna Hofburg, acquired with his imperial guiding principle a corresponding iconic character.

  1. Case report of Ellis-Van Creveld syndrome

    Directory of Open Access Journals (Sweden)

    Baghdadi T

    2001-09-01

    Full Text Available Ellis-van Creveld sydrome (Chondroectodermal dysplasia is a hereditary form of short limb disproportionate dwarfism characterized by diffuse involvement of skeletal system and visceral organs. Two brothers affected by this syndrome are presented here following a brief account of the disease's manifestations.

  2. «Nerites»: contribución al estudio de la mitología marina de la antigua Grecia

    Directory of Open Access Journals (Sweden)

    José Carlos Bermejo Barrera

    1980-06-01

    Full Text Available The present paper considers Aelian, NA XIV 28, which presents a secondary tradition found in two sailors’ tales about Nerites, the brother of the Nereids. Analysis shows that this typical character integrates the two codes of his myth, the zoological code and the mythical-personal code, in the context of Greek myths about the sea.

  3. [Genetic and environmental contribution to rheumatoid arthritis: a family study].

    Science.gov (United States)

    Iebba, Filippo; Di Sora, Fiorella; Leti, Wilma; Montella, Tatiana; Montella, Francesco

    2012-01-01

    We report on the HLA typing of three brothers (A, B, C) with rheumatoid arthritis (RA) and their six sons. This family is interesting for the full concordance for RA between parents. The aim of this study was the discovery of genetic and/or enviromental cofactors determining this absolute concordance.

  4. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... Dignity & Identity CareMAP: Mealtime and Swallowing: Part 2 Walking for a Father and a Brother: Donna’s Story ... Caregivers from Caregivers What Are the Risks and Benefits of DBS Surgery? Ask the Helpline: Why Is ...

  5. “A PERSISTENT EXCEPTION TO TEXTBOOK ECONOMICS”: A HISTORICAL OVERVIEW OF INTERNATIONAL AIRLINES

    Directory of Open Access Journals (Sweden)

    Erik Benson

    2005-01-01

    Full Text Available The recent centennial of the Wright Brothers' flight stimulated study of the history of aviation in general and this historical overview of international airlines in particular. International airlines are commercial enterprises, but their history suggests that the economics behind their development was often overridden lypolitical, diplomatic, strategic, imperial, cultural, and emotional pressures. International airlines have not always been economically rational enterprises.

  6. Full closure strategic analysis.

    Science.gov (United States)

    2014-07-01

    The full closure strategic analysis was conducted to create a decision process whereby full roadway : closures for construction and maintenance activities can be evaluated and approved or denied by CDOT : Traffic personnel. The study reviewed current...

  7. Full page insight

    DEFF Research Database (Denmark)

    Cortsen, Rikke Platz

    2014-01-01

    Alan Moore and his collaborating artists often manipulate time and space by drawing upon the formal elements of comics and making alternative constellations. This article looks at an element that is used frequently in comics of all kinds – the full page – and discusses how it helps shape spatio......, something that it shares with the full page in comics. Through an analysis of several full pages from Moore titles like Swamp Thing, From Hell, Watchmen and Promethea, it is made clear why the full page provides an apt vehicle for an apocalypse in comics....

  8. Reframing Paul’s sibling language in light of Jewish epistolary forms of address

    Directory of Open Access Journals (Sweden)

    Kyu Seop Kim

    2015-06-01

    Full Text Available Recent scholars focus mainly on Paul’s use of ‘brothers (and sisters’ or ‘brother (and sister’ in Greco-Roman epistolary conventions and cultural backdrops. However, Jewish dimensions (particularly ethnic dimensions of Paul’s sibling language still remain unexplored in current scholarship. Furthermore, scholars have not drawn much attention to how Jewish letter writers use sibling terms in their letters. This article offers a new interpretation on Paul’s sibling language in light of its Jewish usage. We should note that Jewish letter writers did not address their Gentile letter recipients as ‘brother(s’. However, Paul did call his recipients ‘brothers’. It is unlikely that Paul employed sibling language without being aware of its common Jewish usage. The author proposes that Paul’s sibling language is used in the context of an ethnic insider designation (shared ethnicity, and that ascribing the title of brother to believers including Gentiles signals the re-definition of the family of Abraham.

  9. The Play Therapy Process of Sibling-Witnesses of Marital Violence

    Directory of Open Access Journals (Sweden)

    Miao-Jung Lin

    2014-06-01

    Full Text Available The purpose of this study is to explore play phases, play themes, and play behaviors in the play therapy processes of two siblings who were child witnesses of marital violence. Consensus qualitative research method was adopted to analyze the data. The results showed four phases in the siblings’ play therapies: the exploratory phase, the trauma phase, the transformation phase, and the ending phase. Within the four phases, same themes that were identified for both siblings were “exploration” in the exploratory phase, “destruction” in the trauma phase, and “blessing” in the ending phase. Differences in play themes were also identified to include “interaction”, “chaos”, “defensiveness”, “threatening” for the older brother during the trauma phase, while the younger of the two displayed “hostility”, “violence/aggression”, and “repetition”. In the transformation phase, the older brother displayed themes of “healing”, “nurturing/tending”, while the younger brother displayed themes of “protection”, “construction”, and “creation”. For the ending phase, the younger brother also displayed themes of “separation” and “wistfulness”. Some recommendations for practitioners and further research in play therapy are provided.

  10. Full Service Leasing

    OpenAIRE

    Richter, Ján

    2009-01-01

    Aim of this master thesis is to describe the service of Full Service Leasing, as a modern form of financing and management of assets, primarily automobile fleet. Description of full service leasing is designed as a comprehensive and complete guide to support reader's position when deciding to finance and manage a fleet by this service. Whether the reader is an entrepreneur, CFO, fleet manager, new employee of leasing company, or anyone who is interested in this service, this master thesis wil...

  11. Compressive full waveform lidar

    Science.gov (United States)

    Yang, Weiyi; Ke, Jun

    2017-05-01

    To avoid high bandwidth detector, fast speed A/D converter, and large size memory disk, a compressive full waveform LIDAR system, which uses a temporally modulated laser instead of a pulsed laser, is studied in this paper. Full waveform data from NEON (National Ecological Observatory Network) are used. Random binary patterns are used to modulate the source. To achieve 0.15 m ranging resolution, a 100 MSPS A/D converter is assumed to make measurements. SPIRAL algorithm with canonical basis is employed when Poisson noise is considered in the low illuminated condition.

  12. Full faith in myself

    Indian Academy of Sciences (India)

    Lawrence

    Full faith in myself. Meenakshi Banerjee. 12. Ihad my schooling at the Irish Convent, Loreto, in Asansol,. West Bengal. Perhaps the earliest memories I have are of myself as a very determined child with a deep appreciation of and inquisitiveness regarding nature although not understanding most of it at that tender age.

  13. Plate Full of Color

    Centers for Disease Control (CDC) Podcasts

    The Eagle Books are a series of four books that are brought to life by wise animal characters - Mr. Eagle, Miss Rabbit, and Coyote - who engage Rain That Dances and his young friends in the joy of physical activity, eating healthy foods, and learning from their elders about health and diabetes prevention. Plate Full of Color teaches the value of eating a variety of colorful and healthy foods.

  14. Sexual offending runs in families: A 37-year nationwide study.

    Science.gov (United States)

    Långström, Niklas; Babchishin, Kelly M; Fazel, Seena; Lichtenstein, Paul; Frisell, Thomas

    2015-04-01

    Sexual crime is an important public health concern. The possible causes of sexual aggression, however, remain uncertain. We examined familial aggregation and the contribution of genetic and environmental factors to sexual crime by linking longitudinal, nationwide Swedish crime and multigenerational family registers. We included all men convicted of any sexual offence (N = 21,566), specifically rape of an adult (N = 6131) and child molestation (N = 4465), from 1973 to 2009. Sexual crime rates among fathers and brothers of sexual offenders were compared with corresponding rates in fathers and brothers of age-matched population control men without sexual crime convictions. We also modelled the relative influence of genetic and environmental factors to the liability of sexual offending. We found strong familial aggregation of sexual crime [odds ratio (OR) = 5.1, 95% confidence interval (CI) = 4.5-5.9] among full brothers of convicted sexual offenders. Familial aggregation was lower in father-son dyads (OR = 3.7, 95% CI = 3.2-4.4) among paternal half-brothers (OR = 2.1, 95% CI = 1.5-2.9) and maternal half-brothers (OR = 1.7, 95% CI = 1.2-2.4). Statistical modelling of the strength and patterns of familial aggregation suggested that genetic factors (40%) and non-shared environmental factors (58%) explained the liability to offend sexually more than shared environmental influences (2%). Further, genetic effects tended to be weaker for rape of an adult (19%) than for child molestation (46%). We report strong evidence of familial clustering of sexual offending, primarily accounted for by genes rather than shared environmental influences. Future research should possibly test the effectiveness of selective prevention efforts for male first-degree relatives of sexually aggressive individuals, and consider familial risk in sexual violence risk assessment.

  15. Plate Full of Color

    Centers for Disease Control (CDC) Podcasts

    2008-08-04

    The Eagle Books are a series of four books that are brought to life by wise animal characters - Mr. Eagle, Miss Rabbit, and Coyote - who engage Rain That Dances and his young friends in the joy of physical activity, eating healthy foods, and learning from their elders about health and diabetes prevention. Plate Full of Color teaches the value of eating a variety of colorful and healthy foods.  Created: 8/4/2008 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2008.

  16. Emptiness and Fullness

    DEFF Research Database (Denmark)

    Bregnbæk, Susanne; Bunkenborg, Mikkel

    As critical voices question the quality, authenticity, and value of people, goods, and words in post-Mao China, accusations of emptiness render things open to new investments of meaning, substance, and value. Exploring the production of lack and desire through fine-grained ethnography, this volume...... examines how diagnoses of emptiness operate in a range of very different domains in contemporary China: In the ostensibly meritocratic exam system and the rhetoric of officials, in underground churches, housing bubbles, and nationalist fantasies, in bodies possessed by spirits and evaluations of jade......, there is a pervasive concern with states of lack and emptiness and the contributions suggest that this play of emptiness and fullness is crucial to ongoing constructions of quality, value, and subjectivity in China....

  17. Kino plaadimasinas / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Areeni muusikakriitikud kuulavad filmimuusika heliplaate: "O Brother, Where Art Thou?", "The Royal Tenenbaums", "Amelie From Montmartre", "Moulin Rouge", "Training Day", "Mulholland Drive", "Ocean's 11"

  18. Ausambad Newfoundlandi eestisoost seenesõpradele / foto: Helen Spencer

    Index Scriptorium Estoniae

    2008-01-01

    Newfoundlandis asuva Brother Brennan Environmental Education Centre (BBEEC) poolt korraldadavatest seenekursustest, mille õppejõuks kutsuti Newfoundlandis seenehuvilistena tuntud Maria ja Andrus Voitk

  19. 75 FR 68911 - Regulations Under the Genetic Information Nondiscrimination Act of 2008

    Science.gov (United States)

    2010-11-09

    ..., biological mother, the mother's brothers, sisters, and their children, maternal grandfather, maternal... risk of conditions such as cystic fibrosis, sickle cell anemia, spinal muscular atrophy, and fragile X...

  20. Pop / Tõnis Kahu

    Index Scriptorium Estoniae

    Kahu, Tõnis, 1962-

    2008-01-01

    Heliplaatidest: Chemical Brothers "Brotherhood", Plutonium 74 "Peittoalueen ulkopuolella", Disturbed "Indestructible", Thomas Feiner & Anywhen "The Opiates Revised", DefRage "Save Us from Religion", Kago "Mopskassi maja"

  1. Full metal jacket!

    CERN Document Server

    Laëtitia Pedroso

    2011-01-01

    Ten years ago, standard issue clothing only gave CERN firemen partial protection but today our fire-fighters are equipped with state-of-the-art, full personal protective equipment.   CERN's Fire Brigade team. For many years, the members of CERN's Fire Brigade went on call-outs clad in their work trousers and fire-rescue coats, which only afforded them partial protection. Today, textile manufacturing techniques have moved on a long way and CERN's firemen are now kitted out with state-of-the-art personal protective equipment. The coat and trousers are three-layered, comprising fire-resistant aramide, a protective membrane and a thermal lining. The CERN Fire Brigade' new state-of-the-art personal protection equipment. "This equipment is fully compliant with the standards in force and is therefore resistant to cuts, abrasion, electrical arcs with thermal effects and, of course, fire," explains Patrick Berlinghi, the CERN Fire Brigade's Logistics Officer. You might think that su...

  2. Policies for full employment

    DEFF Research Database (Denmark)

    de Koning, Jaap; Layard, Richard; Nickel, Stephen

    European unemployment is too high, and employment is too low. Over 7½ per cent of Europe's workforce is unemployed, and only two thirds of people aged 15-64 are in work. At the Lisbon summit two years ago the heads of government set the target that by 2010 the employment rate should rise from 64...... per cent to at least 70 per cent. And for older workers between 55 and 64 the employment rate should rise from 38 per cent to at least one half. These are ambitious targets. They will require two big changes: more people must seek work, and among those seeking work a higher proportion must get a job....... So we need higher participation, and (for full employment) we need a much lower unemployment rate. Can it be done? A mere glance at the experience of different European countries shows that it can. As Table 1 shows, four E.U. countries already exceed the overall target for 2010 (Britain, Denmark...

  3. Into the Curriculum. "Brother, Can You Spare a Dime?" [and] Aboard the Titanic [and] Summarization [and] Public Speaking [and] Western Vocabulary [and] Acid Tests for the Library Media Center [and] Tasha Tudor, How Does Your Garden Grow? [and]"Baa-a-a-ck" to the Farm.

    Science.gov (United States)

    School Library Media Activities Monthly, 1995

    1995-01-01

    Eight curriculum guides are provided for music and social studies; reading/language arts/social studies; reading/language arts; science; science/art; social studies. Objectives, resources, grade level, activity procedures, evaluation and follow-up suggestions are outlined for each activity. (JKP)

  4. Is the association between general cognitive ability and violent crime caused by family-level confounders?

    Directory of Open Access Journals (Sweden)

    Thomas Frisell

    Full Text Available BACKGROUND: Research has consistently found lower cognitive ability to be related to increased risk for violent and other antisocial behaviour. Since this association has remained when adjusting for childhood socioeconomic position, ethnicity, and parental characteristics, it is often assumed to be causal, potentially mediated through school adjustment problems and conduct disorder. Socioeconomic differences are notoriously difficult to quantify, however, and it is possible that the association between intelligence and delinquency suffer substantial residual confounding. METHODS: We linked longitudinal Swedish total population registers to study the association of general cognitive ability (intelligence at age 18 (the Conscript Register, 1980-1993 with the incidence proportion of violent criminal convictions (the Crime Register, 1973-2009, among all men born in Sweden 1961-1975 (N = 700,514. Using probit regression, we controlled for measured childhood socioeconomic variables, and further employed sibling comparisons (family pedigree data from the Multi-Generation Register to adjust for shared familial characteristics. RESULTS: Cognitive ability in early adulthood was inversely associated to having been convicted of a violent crime (β = -0.19, 95% CI: -0.19; -0.18, the association remained when adjusting for childhood socioeconomic factors (β = -0.18, 95% CI: -0.18; -0.17. The association was somewhat lower within half-brothers raised apart (β = -0.16, 95% CI: -0.18; -0.14, within half-brothers raised together (β = -0.13, 95% CI: (-0.15; -0.11, and lower still in full-brother pairs (β = -0.10, 95% CI: -0.11; -0.09. The attenuation among half-brothers raised together and full brothers was too strong to be attributed solely to attenuation from measurement error. DISCUSSION: Our results suggest that the association between general cognitive ability and violent criminality is confounded partly by factors shared by

  5. Is the association between general cognitive ability and violent crime caused by family-level confounders?

    Science.gov (United States)

    Frisell, Thomas; Pawitan, Yudi; Långström, Niklas

    2012-01-01

    Research has consistently found lower cognitive ability to be related to increased risk for violent and other antisocial behaviour. Since this association has remained when adjusting for childhood socioeconomic position, ethnicity, and parental characteristics, it is often assumed to be causal, potentially mediated through school adjustment problems and conduct disorder. Socioeconomic differences are notoriously difficult to quantify, however, and it is possible that the association between intelligence and delinquency suffer substantial residual confounding. We linked longitudinal Swedish total population registers to study the association of general cognitive ability (intelligence) at age 18 (the Conscript Register, 1980-1993) with the incidence proportion of violent criminal convictions (the Crime Register, 1973-2009), among all men born in Sweden 1961-1975 (N = 700,514). Using probit regression, we controlled for measured childhood socioeconomic variables, and further employed sibling comparisons (family pedigree data from the Multi-Generation Register) to adjust for shared familial characteristics. Cognitive ability in early adulthood was inversely associated to having been convicted of a violent crime (β = -0.19, 95% CI: -0.19; -0.18), the association remained when adjusting for childhood socioeconomic factors (β = -0.18, 95% CI: -0.18; -0.17). The association was somewhat lower within half-brothers raised apart (β = -0.16, 95% CI: -0.18; -0.14), within half-brothers raised together (β = -0.13, 95% CI: (-0.15; -0.11), and lower still in full-brother pairs (β = -0.10, 95% CI: -0.11; -0.09). The attenuation among half-brothers raised together and full brothers was too strong to be attributed solely to attenuation from measurement error. Our results suggest that the association between general cognitive ability and violent criminality is confounded partly by factors shared by brothers. However, most of the association remains even

  6. Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

    DEFF Research Database (Denmark)

    Klein, H H; Müller, R; Vestergaard, H

    1999-01-01

    We studied insulin receptor kinase activation in two brothers with congenital muscle fibre type disproportion myopathy and compound heterozygous mutations of the insulin receptor gene, their parents, and their unaffected brother. In the father who has a heterozygote Arg1174-->Gln mutation, in sit...

  7. Adolescent Siblings of Individuals with an Autism Spectrum Disorder: Testing a Diathesis-Stress Model of Sibling Well-Being

    Science.gov (United States)

    Orsmond, Gael I.; Seltzer, Marsha Mailick

    2009-01-01

    The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated…

  8. Storytelling for a Nation

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2007-01-01

    The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)......The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)...

  9. That's Not Montessori

    Science.gov (United States)

    Peters, Dane L.

    2009-01-01

    The author could not contain herself one day at school recently when a parent of three children shared something she had heard from her eldest daughter. That morning, the eldest daughter was grumbling about the fact that she and her Lower Elementary brother had to go to school while her Preschool brother did not, and she announced to her mother,…

  10. The Role of Gender in Youth Mentoring Relationship Formation and Duration

    Science.gov (United States)

    Rhodes, Jean; Lowe, Sarah R.; Litchfield, Leon; Walsh-Samp, Kathy

    2008-01-01

    The role of gender in shaping the course and quality of adult-youth mentoring relationships was examined. The study drew on data from a large, random assignment evaluation of Big Brothers Big Sisters of America (BBSA) programs [Grossman, J. B., & Tierney, J. P. (1998). Does mentoring work? An impact study of the Big Brothers Big Sisters program.…

  11. 20 CFR 633.320 - Nepotism.

    Science.gov (United States)

    2010-04-01

    ... family” means wife, husband, son, daughter, mother, father, brother, brother-in-law, sister, sister-in... position funded under the Act if a member of that person's immediate family is engaged in an administrative... the Act, if a member of that person's immediate family is engaged in an administrative capacity for...

  12. 20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.

    Science.gov (United States)

    2010-04-01

    ... surviving spouse or child, or the surviving dependent brothers or sisters, where there is no surviving... part the term “total disability” shall mean partial disability with respect to a claim for which... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and...

  13. 20 CFR 410.515 - Modification of benefit amounts; general.

    Science.gov (United States)

    2010-04-01

    ..., parent, brother, or sister, the excess earnings from wages and from net earnings from self-employment (see § 410.530) of such miner, parent, brother, or sister, respectively; or (2) Failure to report...); or (3) The receipt by a beneficiary of payments made because of the disability of the miner due to...

  14. 20 CFR 725.533 - Modification of benefits amounts; general.

    Science.gov (United States)

    2010-04-01

    ... partial or total disability due to pneumoconiosis; or (3) In the case of benefits to a parent, brother, or... because of death or partial or total disability due to pneumoconiosis; or (2) Any compensation or benefits... (see § 410.530 of this title) of such parent, brother, sister, or miner, respectively; or (4) The fact...

  15. 20 CFR 410.510 - Computation of benefits.

    Science.gov (United States)

    2010-04-01

    ... surviving child of a miner or widow, or a parent, brother, or sister of a miner, is entitled to benefits for..., brother, or sister of a miner, who establishes entitlement to benefits under the provisions of subpart B... benefits) based on the disability or death due to pneumoconiosis arising out of the coal mine employment of...

  16. 20 CFR 725.520 - Computation of benefits.

    Science.gov (United States)

    2010-04-01

    ... parent, brother, or sister of a miner, is entitled to benefits for a month for which he or she is the... surviving child of a miner or surviving spouse, or a surviving parent, brother, or sister of a miner, who... dependent for purposes of augmentation of benefits) based on the disability or death due to pneumoconiosis...

  17. 10 CFR 1060.501 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... Uniformed Service. (e) Handicapped individual means a person who has a physical or mental disability or..., by blood, marriage, or operation of law, as father, mother, son, daughter, brother, sister, uncle..., father-in-law, mother-in-law, son-in-law, daughter-in-law, brother-in-law, sister-in-law, stepfather...

  18. Maailma börsid uues pöörises / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2008-01-01

    USA-st alanud finantskriis kogub uut hoogu. Investeerimispanga Lehman Brothers päästmine ebaõnnestus ning pank palus kohtult pankrotikaitset. Endine USA keskpanga juht Alan Greenspan ennustab veel mitme suur finantsasutuse pankrotti. Vt. samas: Lehman Brothers; Miks aktsiaturud langevad? Diagramm: USA finantskriisi järgmised ohvrid; Virge Lahe. USA finantskriis kergitab laenu hinda ka Eesti pankades

  19. Asperger's in the Holmes Family

    Science.gov (United States)

    Altschuler, Eric L.

    2013-01-01

    I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock.

  20. Asperger's in the Holmes family.

    Science.gov (United States)

    Altschuler, Eric L

    2013-09-01

    I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock.

  1. In de ban van het incestverbod : analyse van een historische omslag in de verbeelding van erotiek tussen broer en zuster

    NARCIS (Netherlands)

    Coebergh-van der Marck, Marie-Anne

    2012-01-01

    Central in the representation of eroticism between brother and sister, classical theme in litterature and film, stands the incest prohibition as source of tension between similarity and difference. Brother and sister share the same genes and because of this they belong together and go different

  2. Mutant ApoA-1 Amyloidosis in a Family of Five Siblings With Motor Neuron Disease and Dementia

    DEFF Research Database (Denmark)

    Vrethema, Magnus; Mucchiano, Gerd Ingrid

    2011-01-01

    We present a family of fi ve siblings in which three brothers died of motor neuron disease (MND) and in two of them concomitant with dementia. A fourth brother died of myocardial infarction and was found to have extensive aortic intimal apolipoprotein A-1 (ApoA-1) derived amyloid deposits and apo...

  3. Case Report: Allgrove syndrome: an Egyptian family with two ...

    African Journals Online (AJOL)

    Moderate achalasia developed at 9 years in the older brother and showed a slowly progressive course with development of chest pain and dysphagia. Alacrima was not evident before the age of 12 years. The neurological symptoms were less severe in the younger brother. He suffered alacrima that started at age of 11 ...

  4. Book Talk. Books About All Kinds of Heroes.

    Science.gov (United States)

    Freeman, Judy

    1998-01-01

    Presents an annotated listing of books about all kinds of heroes for elementary school students. Stories include the young King Arthur; an assertive, baseball-playing heroine who becomes a princess; an older brother dealing with his younger brother; a Christmas story; civil rights icon Rosa Parks; and the cow who jumped over the moon. (SM)

  5. SCHREINER HOUSE

    African Journals Online (AJOL)

    home after her father's insolvency. Her brother. Theo (23 in 1867), headmaster of the local public school, was head of the little household, with their sister Ettie (17) as housekeeper. In the following year their younger brother Will, then eleven, joined them. The four remained together until 1870 when. Thea and Will went to ...

  6. 38 CFR 1.10 - Eligibility for and disposition of the United States flag for burial purposes.

    Science.gov (United States)

    2010-07-01

    ... separation from such service under conditions other than dishonorable, on or after April 25, 1951. (Authority... issued a flag on application signed by guardian). (iii) Parents, including adoptive, stepparents, and foster parents. (iv) Brothers or sisters, including brothers or sisters of the halfblood. (v) Uncles or...

  7. 38 CFR 17.170 - Autopsies.

    Science.gov (United States)

    2010-07-01

    ... preference among such persons. Usually the spouse is first entitled, except in some situations of separation; followed by children, parents, brothers and sisters, etc. When the next of kin as defined by the laws of decedent's domicile consists of a number of persons as children, parents, brothers and sisters, etc...

  8. Download this PDF file

    African Journals Online (AJOL)

    Owner

    River (1966) in early school, and the name stuck in my memory. Again, my elder brother and his ... I recall that I had tried to make sense of the book. I flipped through my brother's copy. I could ... a rainbow of many colours. The challenge is for ...

  9. Full-scope training simulators

    International Nuclear Information System (INIS)

    Ugedo, E.

    1986-01-01

    The following topics to be covered in this report are: Reasons justifying the use of full-scope simulators for operator qualification. Full-scope simulator description: the control room, the physical models, the computer complex, the instructor's console. Main features of full-scope simulators. Merits of simulator training. The role of full-scope simulators in the training programs. The process of ordering and acquiring a full-scope simulator. Maintaining and updating simulator capabilities. (orig./GL)

  10. Birth order and fluctuating asymmetry: a first look.

    Science.gov (United States)

    Lalumière, M L; Harris, G T; Rice, M E

    1999-01-01

    We investigated the hypothesis that maternal immunoreactivity to male-specific features of the foetus can increase developmental instability. We predicted that the participants' number of older brothers would be positively related to the fluctuating asymmetry of ten bilateral morphological traits. The participants were 40 adult male psychiatric patients and 31 adult male hospital employees. Consistent with the hypothesis, the participants' number of older brothers--but not number of older sisters, younger brothers or younger sisters--was positively associated with fluctuating asymmetry. The patients had significantly larger fluctuating asymmetry scores and tended to have more older brothers than the employees, but the positive relationship between the number of older brothers and fluctuating asymmetry was observed in both groups. PMID:10643079

  11. The betrayal of Edom: Remarks on a claimed tradition

    Directory of Open Access Journals (Sweden)

    Bob Becking

    2016-09-01

    Full Text Available Biblical and post-Biblical texts refer to the tradition of the betrayal of Edom. During theconquest the brother-nation of Edom would have betrayed Judah by choosing sides with the Babylonians. Historical and archaeological evidence for this ‘fact’ is absent or not convincing. It is argued that the occupation of Southern Judah by the Edomites in late Babylonian and/or Persian times would have been the source of this claimed tradition.

  12. Accommodative spasm in siblings: A unique finding

    Directory of Open Access Journals (Sweden)

    Rutstein Robert

    2010-01-01

    Full Text Available Accommodative spasm is a rare condition occurring in children, adolescents, and young adults. A familial tendency for this binocular vision disorder has not been reported. I describe accommodative spasm occurring in a brother and sister. Both children presented on the same day with complaints of headaches and blurred vision. Treatment included cycloplegia drops and bifocals. Siblings of patients having accommodative spasm should receive a detailed eye exam with emphasis on recognition of accommodative spasm.

  13. Contribution to the Catalogue of the painter and illustrator John Vanderbank: Six new Oils with Scenes of The Quixote in the Museum of Pontevedra

    Directory of Open Access Journals (Sweden)

    María Ángeles Tilve Jar

    2014-12-01

    Full Text Available In the Museum of Pontevedra stands out a set of six pictures of small format that narrate scenes of the Quixote. Realized in oil on table, they are works of the Englishman painter and illustrator John Vanderbank (1694-1739. In those pictures he adapts some of the prints that himself designed to illustrate the edition of luxury of Miguel de Cervantes who, promoted by Lord Carteret and printed by the Tonson brothers, was realized in London in 1738.

  14. The Sacramental and Moral-Educational Function of the Christian Orthodox Cult

    Directory of Open Access Journals (Sweden)

    Miron Vasile

    2014-11-01

    Full Text Available The Christian Orthodox Cult intervenes for our Salvation and blessing, gives us the possibility to cherish God and to offer Him our gratitude for the bounties we receive through religious services. This divine Cult helps us stay in touch with Him, deepen our faith, clean our sense, enlighten our mind, become stronger in our decision of doing good deeds and live like brothers in the spirit of the Christian love.

  15. Rome.The Etymological Origins

    Directory of Open Access Journals (Sweden)

    Enrique Cabrejas

    2016-02-01

    Full Text Available The name of Rome was always a great mystery. Through this taxonomic study of Greek and Latin language, Enrique Cabrejas gives us the keys and unpublished answers to understand the etymology of the name. For thousands of years never came to suspect, including about the founder Romulus the reasons for the name and of his brother Remus, plus the unknown place name of the Lazio of the Italian peninsula which housed the foundation of ancient Rome.

  16. Introduction

    Directory of Open Access Journals (Sweden)

    Alfred Hornung

    2012-01-01

    Full Text Available Forty years after the assassination of Dr. Martin Luther King, Jr., the charismatic leader of the civil rights movement, Barack H. Obama was elected the first African American president of the United States of America in 2008. Although U.S. Attorney General Robert Kennedy had predicted in 1961 that a black person could be president like his brother “in the next thirty or forty years,” nobody really expected this kind of victory to come true.

  17. AHP 47: YELLOW-HEAD HORSE

    Directory of Open Access Journals (Sweden)

    Sangs rgyas bkra shis སངས་རྒྱས་བཀྲ་ཤིས།

    2017-04-01

    Full Text Available My family had a stallion we called Rta mgo ser 'Yellow-Head Horse'. Father and two of his brothers occasionally rode it. Father said that Yellow-Head was very wild when it was taken to join local horseraces. I didn't believe that because Yellow-Head was very gentle when Mother rode it to the local monastery and also when I rode it.

  18. Traian Vuia – the Romanian inventor who first flew a powered airplane in 1906

    Directory of Open Access Journals (Sweden)

    Liviu FILIMON

    2011-09-01

    Full Text Available As observed the beginning of heavier than air devices started with Wright Brothers who flew in 1903 the first catapulted airplane equipped with an engine, similar to present motor gliders. In March 1906 took place the first flight of Vuia’s monoplane using on board installations. Since then a real competition between manufacturers has started to improve their airplanes as they become more efficient. Traian Vuia’s first flights and his beginnings are explained below.

  19. Faith-Based Diplomacy: A Pathway to Marginalizing Al-Qa’ida

    Science.gov (United States)

    2013-03-01

    contrast to the Islamist governments 12 that have risen to power since early 2011. The Muslim Brotherhood in Egypt , for example, has advocated a more...Zarqawi who had been misbehaving, and he says, brother, we notice from afar X, Y, and Z is happening. Based on our experience in Egypt and around the...theory: “Al Qaeda is not a traditional hierarchical organization, with a pyramid -style organizational structure, and it does not exercise full command

  20. Full Employment in Industrialized Countries.

    Science.gov (United States)

    Britton, Andrew

    1997-01-01

    Argues that full employment must be acceptable on both social and economic grounds. Examines profound changes in industrialized economies since the 1970s and the diversity of employment contracts. Suggests that difficult policy decisions surround full employment. (SK)

  1. About the composition and processing of precious metals from the Serbian medieval mines

    Directory of Open Access Journals (Sweden)

    Kovačević-Kojić Desanka

    2013-01-01

    Full Text Available Account Books of the Caboga (Kabužić Brothers 1426-1433 (Squarço - Reminder, Diary and Ledger from the Historical Archive of Dubrovnik provide new evidence about the high degree of treatment and composition of precious metals from the Serbian medieval mines. First of all, that the residue, after the purification of unprocessed into fine silver, was copper. Even the price of this process is listed. In the Squarço, in two items in a receipt from 1430, there is previously unknown data about auriferous silver (argento di glama, the composition of which, besides gold, also included copper, and the precisely determined shares of these metals per litre. Apart from the Account Books of the Caboga (Kabužić Brothers, other written sources and hitherto geological explorations have provided no clues regarding the presence of copper in the auriferous silver mines.

  2. Psicosis inducida ("foliex a deux" e intoxicación crónica por plomo.: Reporte de un caso y discusión.

    Directory of Open Access Journals (Sweden)

    Jaime Arias

    1996-04-01

    Full Text Available We report a case of two brothers suffering the same paranoia psychosis. The older one presented an altered consciousness and needed hospitalization. During hospitalization, he was considered as having lead chronic intoxication. The lead serum level was 65 ug/dl (N:<30 ug/dl and the lead hair was 25 pg/gr-tiss (N:<10 pg/gr-tiss. He also presented clinically with encephalopathy, disorder of the autonomic dysfunction. He leaded his body for eleven years because of delutional ideas, and induced these ideas and behavior to his brother (folie a deux. The coincidence between these disorders in extremely rare so we believe this case report is of clinical interesting. (Rev Med Hered 1996; 7: 101-104.

  3. Sibship Size and Gendered Resource Dilution in Different Societal Contexts.

    Directory of Open Access Journals (Sweden)

    Matthijs Kalmijn

    Full Text Available Resource dilution theory hypothesizes that children's educational attainment suffers from being raised with many siblings, as the parental resources have to be shared with more children. Based on economic and cultural theories, we hypothesize that resource dilution is gendered: especially a larger number of brothers is harmful to a person's educational attainment. Using the Survey of Health, Ageing and Retirement in Europe, covering 18 European countries, we show that the number of brothers is more negatively related with the odds of obtaining a college degree than the number of sisters. This holds particularly for women. However, this pattern is weaker in countries that are known to have a more gender-egalitarian climate.

  4. AHP 44: DPAL RGYAL: ARTIST AND PHOTOGRAPHER

    Directory of Open Access Journals (Sweden)

    Klu thar rgyal ཀླུ་ཐར་རྒྱལ།

    2017-02-01

    Full Text Available One sweltering summer afternoon in 2016, my family was enjoying yogurt while sitting in order of age around a table at my home. Father suddenly clapped his leg and blurted out "Oh! I remember!" took his cell phone from his coat pocket and said, "Klu kho, please translate these new Chinese messages for me." "China Mobile is really your best friend! It texts you almost every day!" I joked, taking the phone from his hand. One message was for my older brother, Dpal rgyal. The prefecture government informed Brother (b. 1980 that he was chosen to represent Mtsho lho (Hainan Tibetan Autonomous Prefecture for the 2016 Mtsho sngon (Qinghai Province Disabled Persons vocational skills competition in the photography category. Photography contestants were required to bring their own camera and would take photographs at the competition venue. ...

  5. How Full is Full Employment? : How Tools and Not Theory Explained Full Employment

    NARCIS (Netherlands)

    Rodenburg, P.

    2016-01-01

    The post-war debate on full employment policy was blurred and unclear since the concept of full employment itself was theoretically unclear and un-operational. Unable to theoretically determine the unemployment level of full employment, economists tried to find more empirically based ways to

  6. Developed Turbulence: From Full Simulations to Full Mode Reductions

    NARCIS (Netherlands)

    Grossmann, Siegfried; Lohse, Detlef; Reeh, Achim

    1996-01-01

    Developed Navier-Stokes turbulence is simulated with varying wave-vector mode reductions. The flatness and the skewness of the velocity derivative depend on the degree of mode reduction. They show a crossover towards the value of the full numerical simulation when the viscous subrange starts to be

  7. The Boston Marathon Bombers: the Lethal Cocktail that Turned Troubled Youth to Terrorism

    Directory of Open Access Journals (Sweden)

    Anne Speckhard

    2013-06-01

    Full Text Available The Tsarnaev brothers came from the war-torn Chechen diaspora and found asylum in the United States. The elder brother,Tamerlan, carried actual memories of fleeing from the 1994-96 Chechen war. He also lived in Dagestan for a year at the time when the Chechen warlord Basayev was engaging in a campaign of more than thirty suicide attacks, including mass hostage takings. When Tamerlan made it to the United States, he tried to assimilate but failed to make it. The family struggled hard to make a living in the U.S.; but in the end the parents divorced and the father returned to Dagestan. Dzhokhar, the younger brother, made it into an American university but Tamerlan did not succeed in higher education, trying to pursue a boxing career instead. When his immigration status precluded a boxing career, he became disillusioned. Meanwhile his mother, concerned about his descent into smoking marijuana and drinking alcohol, arranged an Islamic tutor for him. The ingredients for the lethal cocktail of terrorism came together when Tamerlan's individual vulnerabilities made him seek online contacts via the Internet and brought him in touch with offline mentors, militants and extremists who glorified Al-Qaeda’s global jihad. Through these channels he became receptive to the terrorist ideology, found a jihadist group with global reach to align with, received technical instructions from the Inspire magazine and found enough support for executing the Boston marathon attack, pulling his younger brother along and dying in the process as he had expected.

  8. Cine club

    CERN Document Server

    Cine club

    2017-01-01

    Wednesday 21 June 2017 at 20:00 CERN Council Chamber Soul Kitchen Directed by Fatih Akin Germany / France / Italy, 2009, 99 minutes In Hamburg, Zinos has a restaurant serving poor-man's fare; he gets by, but his girlfriend has taken a job in Shanghai, he's hurt his back and can't cook, his feckless brother can be on daily parole from jail only if Zinos employs him (though his brother doesn't want to work), a school acquaintance wants to buy the restaurant property, and the tax authority and health inspector are on his case. Zinos hires a temperamental chef and loses all his customers, signs a power of attorney giving his brother full authority at the restaurant, and buys a ticket to Shanghai. Is this a recipe for disaster? Original version German / Greek / Spanish / Turkish / English; English subtitles Wednesday 28 June 2017 at 20:00 CERN Council Chamber In July (Im Juli) Directed by Fatih Akin Germany, 2000, 99 minutes Daniel is a young teacher who, in contrast to ever...

  9. Comparative Analysis of Liability Cases for Bankruptcies of Financial Institutions

    Directory of Open Access Journals (Sweden)

    Julija Kiršienė

    2017-09-01

    Full Text Available The bankruptcy of the fourth largest investment bank in the world Lehman Brothers Holdings Inc. in 2008 remains the largest bankruptcy in the history of United States. This bankruptcy is viewed as a turning point in the Global Financial Crisis. Paradoxically, even though the financial system had many safeguards (auditors, audit committees, the board of directors, credit rating agencies, government supervisors whose purpose was to inform the investing public about the actual financial situation of the institution, Lehman Brothers bankruptcy came as a shock to financial markets across the globe revealing that many of the “gatekeepers” failed. Comparative analysis of liability cases after bankruptcies of Lehman Brothers and financial institutions in Lithuania shows that contrary to Lehman’s case, the demise of financial institutions in Lithuania cannot be attributed to sub-prime mortgages caused financial crisis, real estate market fluctuations or any other external variable. Problems are related to weak supervision, inefficient regulation, and common unethical behavior in the financial sector.

  10. A study about siblings in the face of intellectual disability

    Directory of Open Access Journals (Sweden)

    Olga Lizasoain

    2010-05-01

    Full Text Available Research has shown that siblings of a person with intellectual disabilities can present problems of identification and socialization, the need for compensation, early adoption of large responsibilities, feelings of abandonment, guilt, shame or sadness. Nevertheless, if the needs of these brothers and sisters are facing, disability can become a source of personal and family enrichment. This article presents the initial conclusions drawn after a series of personal interviews conducted with siblings of students in a special education school. Awareness of the issue leads us to approach this study with the aim of providing guidelines of intervention to help siblings to minimize the potential negative impact of having a brother or sister with intellectual disabilities, and facilitate the development of attitudes and behaviours that enable them to face stressful situations in a constructive manner. Thanks to the direct experience of those who have been confronted with this situation, is issued to prevent psychosocial problems associated with having a brother or sister with these features.

  11. Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.

    Directory of Open Access Journals (Sweden)

    Doug P Vanderlaan

    Full Text Available In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect. In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768. Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.

  12. Electoral system and electoral campaign in Ancient Rome

    Directory of Open Access Journals (Sweden)

    Notari Tamaš

    2011-01-01

    Full Text Available One of the most famous orators of the Antiquity, Marcus Tullius Cicero entered the election for the consul's position held in 64 B.C. arranged under extremely disturbed circumstances and he won the consulatus for 63 B.C. Difficulties were caused among others by the fact that an indebted nobleman called Lucius Sergius Catilina saw the only breakthrough for ensuring his political and financial survival in being elected consul, and manifested that in case he would lose he would be willing to take as well violent actions (later, he actually carried out his threats. The orator's younger brother, Quintus Tullius Cicero wanted to help his brother in his campaign foreseen as having quite a lot of turns; so, he wrote a manual for him on the lawful and illegal instruments that could be used in the elections. This work, Commentariolum petitionis (A Handbook for Applicants for Offices is the first summary of campaign strategy in the history of mankind. In addition to the evaluation of the given situation, the presentation (and exploitation of the weaknesses of counter nominees, the book provides advice on several counts that might possibly continue to have relevance even today. We do not know to what extent the experienced politician, Cicero adhered to his younger brother's advice; it is, however, a fact that he was elected consul, and as a consul he defeated Catilina's revolt in. 63 B.C.

  13. Full-F gyrofluid model

    DEFF Research Database (Denmark)

    Madsen, Jens

    2013-01-01

    variables. The fluid moment hierarchy is closed by approximating the gyrokinetic distribution function as a finite order Hermite-Laguerre polynomial and by determining closure approximations for terms involving the gyrokinetic gyro-averaging operator. The model exactly conserves the gyrokinetic full......A global electromagnetic gyrofluid model based on the full-F gyrokinetic model is derived. The gyrofluid moment variables are not split into fluctuating and equilibrium parts. Profiles are evolved freely, and gyro-averaging operators are not parametrized, but are functions of the gyrofluid moment...

  14. The Fiction of Full BEKK

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); M.J. McAleer (Michael)

    2017-01-01

    textabstractThe purpose of the paper is to show that univariate GARCH is not a special case of multivariate GARCH, specifically the Full BEKK model, except under parametric restrictions on the off-diagonal elements of the random coefficient autoregressive coefficient matrix, provides the regularity

  15. Empty calories and phantom fullness

    NARCIS (Netherlands)

    Camps, Guido; Mars, Monica; Graaf, de Kees; Smeets, Paul A.M.

    2016-01-01

    Background: Stomach fullness is a determinant of satiety. Although both the viscosity and energy content have been shown to delay gastric emptying, their relative importance is not well understood. Objective: We compared the relative effects of and interactions between the viscosity and energy

  16. Toward full MOX core design

    International Nuclear Information System (INIS)

    Rouviere, G.; Guillet, J.L.; Bruna, G.B.; Pelet, J.

    1999-01-01

    This paper presents a selection of the main preliminary results of a study program sponsored by COGEMA and currently carried out by FRAMATOME. The objective of this study is to investigate the feasibility of full MOX core loading in a French 1300 MWe PWR, a recent and widespread standard nuclear power plant. The investigation includes core nuclear design, thermal hydraulic and systems aspects. (authors)

  17. Rectilinear Full Steiner Tree Generation

    DEFF Research Database (Denmark)

    Zachariasen, Martin

    1999-01-01

    The fastest exact algorithm (in practice) for the rectilinear Steiner tree problem in the plane uses a two-phase scheme: First, a small but sufficient set of full Steiner trees (FSTs) is generated and then a Steiner minimum tree is constructed from this set by using simple backtrack search, dynamic...

  18. Full autonomy; Autarkie im Komplettpaket

    Energy Technology Data Exchange (ETDEWEB)

    Augsten, Eva

    2011-05-31

    Normally, those who talk of full solar autonomy refer to the annual balance of a house. Now, architect Timo Leukefeld and Helma Eigenheimbau AG presented a really autonomous solar house which is available on a turnkey basis for 363,000 Euros.

  19. [Endoscopic full-thickness resection].

    Science.gov (United States)

    Meier, B; Schmidt, A; Caca, K

    2016-08-01

    Conventional endoscopic resection techniques such as endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) are powerful tools for the treatment of gastrointestinal (GI) neoplasms. However, those techniques are limited to the superficial layers of the GI wall (mucosa and submucosa). Lesions without lifting sign (usually arising from deeper layers) or lesions in difficult anatomic positions (appendix, diverticulum) are difficult - if not impossible - to resect using conventional techniques, due to the increased risk of complications. For larger lesions (>2 cm), ESD appears to be superior to the conventional techniques because of the en bloc resection, but the procedure is technically challenging, time consuming, and associated with complications even in experienced hands. Since the development of the over-the-scope clips (OTSC), complications like bleeding or perforation can be endoscopically better managed. In recent years, different endoscopic full-thickness resection techniques came to the focus of interventional endoscopy. Since September 2014, the full-thickness resection device (FTRD) has the CE marking in Europe for full-thickness resection in the lower GI tract. Technically the device is based on the OTSC system and combines OTSC application and snare polypectomy in one step. This study shows all full-thickness resection techniques currently available, but clearly focuses on the experience with the FTRD in the lower GI tract.

  20. Workflows for Full Waveform Inversions

    Science.gov (United States)

    Boehm, Christian; Krischer, Lion; Afanasiev, Michael; van Driel, Martin; May, Dave A.; Rietmann, Max; Fichtner, Andreas

    2017-04-01

    Despite many theoretical advances and the increasing availability of high-performance computing clusters, full seismic waveform inversions still face considerable challenges regarding data and workflow management. While the community has access to solvers which can harness modern heterogeneous computing architectures, the computational bottleneck has fallen to these often manpower-bounded issues that need to be overcome to facilitate further progress. Modern inversions involve huge amounts of data and require a tight integration between numerical PDE solvers, data acquisition and processing systems, nonlinear optimization libraries, and job orchestration frameworks. To this end we created a set of libraries and applications revolving around Salvus (http://salvus.io), a novel software package designed to solve large-scale full waveform inverse problems. This presentation focuses on solving passive source seismic full waveform inversions from local to global scales with Salvus. We discuss (i) design choices for the aforementioned components required for full waveform modeling and inversion, (ii) their implementation in the Salvus framework, and (iii) how it is all tied together by a usable workflow system. We combine state-of-the-art algorithms ranging from high-order finite-element solutions of the wave equation to quasi-Newton optimization algorithms using trust-region methods that can handle inexact derivatives. All is steered by an automated interactive graph-based workflow framework capable of orchestrating all necessary pieces. This naturally facilitates the creation of new Earth models and hopefully sparks new scientific insights. Additionally, and even more importantly, it enhances reproducibility and reliability of the final results.

  1. Full system decontamination feasibility studies

    International Nuclear Information System (INIS)

    Denault, R.P.; LeSurf, J.E.; Walschot, F.W.

    1988-01-01

    Many chemical decontaminations have been performed on subsystems in light water reactors (BWRs and PWRs) but none on the full system (including the fuel) of large, (>500 MWe) investor owned reactors. Full system decontaminations on pressure-tubed reactors have been shown to facilitate maintenance, inspection, repair and replacement of reactor components. Further advantages are increased reactor availability and plant life extension. A conceptual study has been performed for EPRI (for PWRs) and Commonwealth Edison Co (for BWRs) into the applicability and cost benefit of full system decontaminations (FSD). The joint study showed that FSDs in both PWRs and BWRs, with or without the fuel included in the decontamination, are feasible and cost beneficial provided a large amount of work is to be done following the decontamination. The large amounts of radioactive waste generated can be managed using current technologies. Considerable improvements in waste handling, and consequent cost savings, can be obtained if new techniques which are now reaching commercial application are used. (author)

  2. LHCb : Full Experiment System Test

    CERN Multimedia

    Cattaneo, M

    2009-01-01

    LHCb had been planning to commission its High Level Trigger software and Data Quality monitoring procedures using real collisions data from the LHC pilot run. Following the LHC incident on 19th September 2008, it was decided to commission the system using simulated data. This “Full Experiment System Test” consists of: - Injection of simulated minimum bias events into the full HLT farm, after selection by a simulated Level 0 trigger. - Processing in the HLT farm to achieve the output rate expected for nominal LHC luminosity running, sustained over the typical duration of an LHC fill. - Real time Data Quality validation of the HLT output, validation of calibration and alignment parameters for use in the reconstruction. - Transmission of the event data, calibration data and book-keeping information to Tier1 sites and full reconstruction of the event data. - Data Quality validation of the reconstruction output. We will report on the preparations and results of FEST09, and on the status of commissioning for no...

  3. A full quantum network scheme

    International Nuclear Information System (INIS)

    Ma Hai-Qiang; Wei Ke-Jin; Yang Jian-Hui; Li Rui-Xue; Zhu Wu

    2014-01-01

    We present a full quantum network scheme using a modified BB84 protocol. Unlike other quantum network schemes, it allows quantum keys to be distributed between two arbitrary users with the help of an intermediary detecting user. Moreover, it has good expansibility and prevents all potential attacks using loopholes in a detector, so it is more practical to apply. Because the fiber birefringence effects are automatically compensated, the scheme is distinctly stable in principle and in experiment. The simple components for every user make our scheme easier for many applications. The experimental results demonstrate the stability and feasibility of this scheme. (general)

  4. Cusiana Cupiagua. Towards full production

    International Nuclear Information System (INIS)

    Carta Petrolera

    1998-01-01

    When production facilities at Cupiagua are ready around mid-year, the Cusiana Cupiagua complex will start full production, this is the largest oil project in Colombia to date. The Cupiagua CPF covers over 60 hectares on the tableland of the same name in the jurisdiction of Aguazul, a town in Casanare province in northeast Colombia, and currently considered the country's oil cradle. Work is being carried out in a sort of niche that appears to be protected by a natural wall made up of the folds of the Casanare foothills

  5. Global Prospects for Full Employment

    Directory of Open Access Journals (Sweden)

    Ivo Šlaus

    2011-04-01

    Full Text Available The recent international financial crisis highlights the crucial role of employment in human welfare and social stability. Access to remunerative employment opportunities is essential for economic security in a market-based economic system. As the rise of democracy compelled nations to extend the voting right to all citizens, employment must be recognized as a fundamental human right. In total defiance of conventional wisdom, since 1950 job growth has outpaced the explosive growth of population, the rapid adoption of labor-saving technologies, the manifold expansion of world trade, and the dramatic shift from manual labor to white collar work. In an increasingly globalized labor market, current nation-centric theories and models of employment need to be replaced with a human-centered global perspective complemented by new indicators that recognize the central and essential contribution of employment to human economic welfare. Employment and economy are subsets of society and their growth is driven by the more fundamental process of social development. A vast array of unmet social needs combined with an enormous reservoir of underutilized social resources – technological, scientific, educational, organizational, cultural and psychological – can be harnessed to dramatically expand employment opportunities and achieve full employment on a global basis. This paper examines the theoretical basis, policy issues and strategies required to eradicate unemployment nationally and globally.

  6. Achieving and sustaining full employment.

    Science.gov (United States)

    Rosen, S M

    1995-01-01

    Human rights and public health considerations provide strong support for policies that maximize employment. Ample historical and conceptual evidence supports the feasibility of full employment policies. New factors affecting the labor force, the rate of technological change, and the globalization of economic activity require appropriate policies--international as well as national--but do not invalidate the ability of modern states to apply the measures needed. Among these the most important include: (I) systematic reduction in working time with no loss of income, (2) active labor market policies, (3) use of fiscal and monetary measures to sustain the needed level of aggregate demand, (4) restoration of equal bargaining power between labor and capital, (5) social investment in neglected and outmoded infrastructure, (6) accountability of corporations for decisions to shift or reduce capital investment, (7) major reductions in military spending, to be replaced by socially needed and economically productive expenditures, (8) direct public sector job creation, (9) reform of monetary policy to restore emphasis on minimizing unemployment and promoting full employment. None are without precedent in modern economies. The obstacles are ideological and political. To overcome them will require intellectual clarity and effective advocacy.

  7. Review Document: Full Software Trigger

    CERN Document Server

    Albrecht, J; Raven, G

    2014-01-01

    This document presents a trigger system for the upgraded LHCb detector, scheduled to begin operation in 2020. This document serves as input for the internal review towards the "DAQ, online and trigger TDR". The proposed trigger system is implemented entirely in software. In this document we show that track reconstruction of a similar quality to that available in the offline algorithms can be performed on the full inelastic $pp$-collision rate, without prior event selections implemented in custom hardware and without relying upon a partial event reconstruction. A track nding eciency of 98.8 % relative to oine can be achieved for tracks with $p_T >$ 500 MeV/$c$. The CPU time required for this reconstruction is about 40 % of the available budget. Proof-of-principle selections are presented which demonstrate that excellent performance is achievable using an inclusive beauty trigger, in addition to exclusive beauty and charm triggers. Finally, it is shown that exclusive beauty and charm selections that do not intr...

  8. The political parties and significant personalities of the Bessarabian Zemstvo (1869-1917

    Directory of Open Access Journals (Sweden)

    Valentin Tomuleţ

    2017-12-01

    Full Text Available This article focuses on some parties and significant personalities who worked in the Bessarabian institution of local self-government – Zemstvo (created in 1869 and contributed to the development of the province. The authors found that some nobles united and formed political parties. Parties of the Zemstvo were groups of persons related to the most influential families from Bessarabia. For some of them the Zemstvo served as a platform on which the nobles could solve their problems. It can be said that the Zemstvo was the “alter ego” of the Bessarabian nobility. As a result, in the political life of Bessarabia two main parties were formed – “Young Bessarabia” (“Molodaya Bessarabiya” and “Old Greek Party” (Starogrecheskaya”, which succeeded each other at the helm of power. In the early 1880s, the “Old Greek party” finally defeated its rival and gained full power in the Bessarabian Zemstvo administration. Counselors saw in the Bessarabian Zemstvo an important and reliable instrument for committing abuses. For example, the Head of the Orhei Zemstvo Council Cozac embezzled money from the Zemstvo budget. When the fact of the theft was uncovered, and this was written about in the press, Cozac shot himself. Each group of the nobles included not only people related to certain interest in economic and political life of Bessarabia, but also people related by kinship, acting in the family interests. In 1881-1884, 18 of the 52 provincial councelors were relatives: brothers Semigradov (4 people, brothers Krupensky, brothers Sinadino, brothers Dunca, brothers Cotruta (2 people. The Krupensky family was the most influential family in the Bessarabian Zemstvo. The publicist P. Krushevan wrote in this regard that the Krupensky clan usurped all the power in Bessarabia, and the Governor S. Urusov noted their importance in economic and political life of the province. Many members of the Zemstvo left their mark in the economic, political, and

  9. Full MOX core for PWRs

    International Nuclear Information System (INIS)

    Puill, A.; Aniel-Buchheit, S.

    1997-01-01

    Plutonium management is a major problem of the back end of the fuel cycle. Fabrication costs must be reduced and plant operation simplified. The design of a full MOX PWR core would enable the number of reactors devoted to plutonium recycling to be reduced and fuel zoning to be eliminated. This paper is a contribution to the feasibility studies for achieving such a core without fundamental modification of the current design. In view of the differences observed between uranium and plutonium characteristics it seems necessary to reconsider the safety of a MOX-fuelled PWR. Reduction of the control worth and modification of the moderator density coefficient are the main consequences of using MOX fuel in a PWR. The core reactivity change during a draining or a cooling is thus of prime interest. The study of core global draining leads to the following conclusion: only plutonium fuels of very poor quality (i.e. with low fissile content) cannot be used in a 900 MWe PWR because of a positive global voiding reactivity effect. During a cooling accident, like an spurious opening of a secondary-side valve, the hypothetical return to criticality of a 100% MOX core controlled by means of 57 control rod clusters (made of hafnium-clad B 4 C rods with a 90% 10 B content) depends on the isotopic plutonium composition. But safety criteria can be complied with for all isotopic compositions provided the 10 B content of the soluble boron is increased to a value of 40%. Core global draining and cooling accidents do not present any major obstacle to the feasibility of a 100% MOX PWR, only minor hardware modifications will be required. (author)

  10. An unusual occurrence of repeated single allele variation on Y-STR locus DYS458

    OpenAIRE

    Shrivastava, Pankaj; Trivedi, Veena Ben; Jain, Toshi; Ali, Mehmood

    2016-01-01

    Six brothers were accused of gagging and raping a woman. A single male Y-STR profile was obtained from vaginal smear swab and clothes of the victim, which did not match with the DNA profile of the accused brothers. As a reference point, the blood sample of their father (aged 87 years) was also analyzed with the same kit. The Y-STR haplotype of all six brothers was found to be the same as that of their father except at locus DYS458. At this locus, while the eldest, second and fourth siblings s...

  11. The Impact of Sibling Sex Composition on Women's Educational Achievements: A Unique Natural Experiment by Twins Gender Shocks

    OpenAIRE

    Chen, Stacey; Chen, Yen-Chien; Liu, Jin-Tan

    2008-01-01

    In a pro-male biased society, brothers may reduce the parental investment re- ceived by female siblings, if parents face time or financial constraints. But brothers may also cause positive externalities. Using more than 12,000 ¯rstborn twins from a highly sex-imbalanced economy, Taiwan, we test if women have fewer opportunities to attend college if they have a brother rather than a sister. To minimize the prob- lem of sex selection, we exploit the fact that twin sex is random given the sex of...

  12. Sibling rivalry and the gender gap: evidence from child health outcomes in Ghana.

    Science.gov (United States)

    Garg, A; Morduch, J

    1998-01-01

    "When capital and labor markets are imperfect, choice sets narrow, and parents must choose how to ration available funds and time between their children. One consequence is that children become rivals for household resources. In economies with pro-male bias, such rivalries can yield gains to having relatively more sisters than brothers. Using a rich household survey from Ghana [the 1988-1989 Ghana Living Standards Survey], we find that on average if children had all sisters (and no brothers) they would do roughly 25-40% better on measured health indicators than if they had all brothers (and no sisters)." excerpt

  13. The Tlingit Indians of Southeastern Alaska: Social Studies Unit for Elementary Grades. Teacher's Manual [And] Kiksadi Dog Salmon Legend [And] Halibut Fishing [And] How Raven Stole the Light: A Radio Play [And] Raven, The Old Woman of the Tides, and the Sea Urchins: A Puppet Play [And] Raven and the Fog Woman [And] The Legendary Adventures of Raven [And] A Tlingit Uncle and His Nephews [And] Three Brothers [And] Lingit Aanee....

    Science.gov (United States)

    Partnow, Patricia H.; And Others

    Part of a series designed to introduce the culture of the Alaskan Indians to elementary school students, the unit contains materials related to seasonal Tlingit activities and a guide for elementary classroom teachers to implement the student materials. The guide describes the format of the unit, suggests activities, lists resource materials, and…

  14. 32 CFR 751.5 - Definitions.

    Science.gov (United States)

    2010-07-01

    ..., snags, or stains on clothing. Claims that electrical or electronic devices were damaged by a power surge...) Spouse; (ii) Child or children; (iii) Father, mother, or both; (iv) Brother, sister, or both. (b...

  15. Effect of resistance and aerobic exercises on bone mineral density ...

    African Journals Online (AJOL)

    Mohamed A. Eid

    2014-01-07

    : There was no significant difference between both groups in the ... ensure better quality of life in patients with hemophilia [5]. It .... placed under the affected knee joint and the child ..... New Delhi: Jaypee Brothers Medical Pub-.

  16. Uued heliplaadid / Koit Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Koit

    1999-01-01

    Uute heliplaatide tutvustus : Peshay "Miles From Home", kogumik "Essential Selection Presents Human Traffic", Great White "Can"t Get There From Here", Ratt "Ratt", RZA "The RZA Hits", Insane Clown Posse "The Amazing Jackal Brothers"

  17. An unusual variant of Becker muscular dystrophy

    NARCIS (Netherlands)

    de Visser, M.; Bakker, E.; Defesche, J. C.; Bolhuis, P. A.; van Ommen, G. J.

    1990-01-01

    We report on 5 brothers with slowly progressive limbgirdle weakness. Calf hypertrophy was absent. The levels of creatine kinase, electromyography, and findings from a muscle biopsy specimen were compatible with muscular dystrophy. The propositus's biopsy specimen also showed numerous rimmed

  18. 76 FR 1402 - Notice of allocation of Tariff Rate Quotas (TRQ) on the Import of Certain Worsted Wool Fabrics...

    Science.gov (United States)

    2011-01-10

    ...--Rochester, NY, Elevee Custom Clothing--Van Nuys, CA, Retail Brand Alliance, Inc. d/b/a Brooks Brothers--New... provides that HTS 9902.51.16 is for the benefit of persons (including firms, corporations, or other legal...

  19. 17 CFR 210.9-03 - Balance sheets.

    Science.gov (United States)

    2010-04-01

    ... the beginning of the period, new loans, repayments, and other changes. (Other changes, if significant...; siblings; mothers and fathers-in-law; sons and daughters-in-law; and brothers and sisters-in-law. Ordinary...

  20. Popmuusika / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2006-01-01

    Uutest heliplaatidest Yeah Yeah Yeahs "Show Your Bones", Cesaria Evora "Rogamar", Aqua Bassino "Rue De Paris", A-Rühm "Leegion", Prefuse 73 "Security Screenings", Bauchklang "Vocal Groove Project", Scala & Kolancy Brothers "Grezenlos"

  1. James Blunt matuselaulude edetabeli tipus

    Index Scriptorium Estoniae

    2006-01-01

    Bereavement Registeri andmetel Suurbritannias matustel tellitavate laulude edetabelis: James Blunt "Goodbye My Lover", Robbie Williams "Angels", Jennifer Warnes ja Bill Medley "I've Had the Time Of My Life", Elton John "Candle in the Wind", Righteous Brothers "Unchained Melody"

  2. USA suurpanga krahh mõjutab siiski ka Eestit / Helga Koger

    Index Scriptorium Estoniae

    Koger, Helga, 1945-

    2008-01-01

    USA suuruselt neljas investeerimispank Lehman Brothers andis kohtusse avalduse pankrotimenetluseks. Endise Hansapanga juhatuse esimees Erkki Raasuke ei näe emapank Swedbanki positsioonidest tulenevalt Eesti või Balti pangandusega mingeid seoseid. Lisa: Lehmaniga seotud varad

  3. Kuula. Kuu artist Carla Bruni. Kuu plaat / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2008-01-01

    Lauljast Carla Brunist. Heliplaatidest: "Mamma mia", The Feeling "Join With Us", The Chemical Brothers "Brotherhood", Pia Fraus "Ten Remixes of Yenissey", Katy Perry "One of the Boys", Lady Gaga "The Fame"

  4. [The sibling status effects and the personality scales of the MMPI].

    Science.gov (United States)

    Hama, H; Mine, H; Mine, H; Matsuyama, Y

    1987-06-01

    The purpose of this study is to find out if the personalities of siblings are similar or different. Subjects used were Doshisha University students and members of their families, provided those families had only two children. Altogether 29 pairs of boys and their younger brothers, 47 pairs of boys and their younger sisters, 44 pairs of girls and their younger brothers, and 51 pairs of girls and their younger sisters were given the MMPI individually. Sibling status effects were found in many of the MMPI scores according to the type of sibling dyads and birth order, especially for the sibling dyad of elder brother and younger sister. Personality relationships between the first and second child showed that there were significant correlations in many MMPI scales: L, K, Pd, Pa, Pt, Sc, Si, Conflict resolution, Manifest anxiety, Repression-Sensitization, and Hostility. Among the four types of sibling dyad, the pairs of girls and their younger brothers showed the highest correlation in their personality.

  5. This is My Family

    OpenAIRE

    Yeğen, Hale Nur; Çetin, Merve

    2017-01-01

    Me and my family, Families poem, Mother-Father, Brother-Sister, Grandparents, Uncle-Aunt, Cousin, Family, Family handgame, My family tree, Activities (Three In a Family), Digital Games, A family poem, Quiz

  6. V cizích službách. Život a smrt pražského fundatisty

    Czech Academy of Sciences Publication Activity Database

    Freemanová, Michaela

    2012-01-01

    Roč. 31, - (2012), s. 317-327 ISSN 0231-7443 Institutional support: RVO:68378076 Keywords : Brothers Hospitallers' Hospital * boy Choristers * Prague * 18th Century * boy s and young men Subject RIV: AL - Art, Architecture, Cultural Heritage

  7. Ethical Dilemma and Management of Infertility in HIV Seropositive ...

    African Journals Online (AJOL)

    aunts, uncles, sisters, brothers and in‑laws all work as a unit through life. Family relationships are guided by hierarchy and seniority. Individuals .... Nevertheless, the physician has to weigh the balance of the ... Ethical issues in professional life.

  8. Anonymous letters? DNA and fingerprints technologies combined to solve a case.

    Science.gov (United States)

    Barbaro, A; Cormaci, P; Teatino, A; La Marca, A; Barbaro, A

    2004-12-02

    Two brothers, living in two different cities, received two different anonymous letters. We performed latent prints development and DNA research on the letters and also on a glass used by a cousin suspected to be the letters' sender.

  9. An Assessment of New Applications for Single-Crystal Piezoelectric Materials

    National Research Council Canada - National Science Library

    Veitch, Lisa

    1998-01-01

    Piezoelectricity was first discovered by the Curie brothers in 1880. During the 1940s, piezoelectric ceramic materials were first used in commercial devices, and new materials and other applications have continued to develop over the years...

  10. Pop / Lauri Tikerpe

    Index Scriptorium Estoniae

    Tikerpe, Lauri

    2005-01-01

    Heliplaatidest: Little Brother "The Minstrel Show", Jackson and his Computer Band "Smash", Matthew Herbert "Plat du Jour", Porn Sword Tobacco "Explains Freedom", Jamiroquai "Dynamite", Ryan Adams and the Cardinals "Jacksonville City Nights", The Dandy Warhols "Odditorium", Neil Young "Prairie Wind"

  11. Progressive cerebellar atrophy and polyneuropathy: expanding the spectrum of PNKP mutations

    NARCIS (Netherlands)

    Poulton, C.; Oegema, R.; Heijsman, D.; Hoogeboom, J.; Schot, R.; Stroink, H.; Willemsen, M.A.A.P.; Verheijen, F.W.; Spek, P. van der; Kremer, A.; Mancini, G.M.S.

    2013-01-01

    We present a neurodegenerative disorder starting in early childhood of two brothers consisting of severe progressive polyneuropathy, severe progressive cerebellar atrophy, microcephaly, mild epilepsy, and intellectual disability. The cause of this rare syndrome was found to be a homozygous mutation

  12. Predictors of future caregiving by adult siblings of individuals with intellectual and developmental disabilities.

    Science.gov (United States)

    Burke, Meghan M; Taylor, Julie Lounds; Urbano, Richard; Hodapp, Robert M

    2012-01-01

    With the growing life expectancy for individuals with intellectual and developmental disabilities, siblings will increasingly assume responsibility for the care of their brother or sister with intellectual and developmental disabilities. Using a 163-item survey completed by 757 siblings, the authors identified factors related to future caregiving expectations. Siblings expected to assume greater caregiving responsibility for their brother or sister with disabilities if they were female, had closer relationships with and lived closer to their brother or sister with intellectual and developmental disabilities, and were the lone sibling without a disability. Siblings who expected to assume higher levels of caregiving had parents who were currently more able to care for their brother or sister with disabilities. With a better understanding of who intends to fulfill future caregiving roles, support can be provided to these siblings.

  13. Childhood Leukemia

    Science.gov (United States)

    ... acute types. Symptoms include Infections Fever Loss of appetite Tiredness Easy bruising or bleeding Swollen lymph nodes Night sweats Shortness of breath Pain in the bones or joints Risk factors for childhood leukemia include having a brother ...

  14. AFRREV IJAH, Vol.1 (4) November, 2012

    African Journals Online (AJOL)

    First Lady

    This study examined the effects of self esteem, emotional health, and social competence .... They may also have telling consequences on the larger society in the areas ..... brothers and delinquency: Evaluating social influence during early and ...

  15. 42 CFR 51c.304 - Governing board.

    Science.gov (United States)

    2010-10-01

    ... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an... procedures, salary and benefit scales, employee grievance procedures, and equal opportunity practices; (iii...

  16. Plaadid : Pop & rock / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Uutest plaatidest Chemical Brothers "Come With Us", Air "Everybody Hetrz", "The Greatest Love Songs Ever", Nightlight Duo "Jäljed liival", closer To heaven ئ original Cast Recording, Sophie Ellis-Bextor "Read My Lips", Andreas Johnson "Deadly Happy"

  17. 20 CFR 410.633 - Additional parties to the hearing.

    Science.gov (United States)

    2010-04-01

    ... OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Determinations of Disability, Other Determinations... hearing. A widow, child, parent, brother, sister, or representative of a decedent's estate, who makes a...

  18. 20 CFR 416.1166a - How we deem income to you from your sponsor if you are an alien.

    Science.gov (United States)

    2010-04-01

    ... determine your eligibility for SSI benefits beginning with the month in which your disability or blindness... deemed to Mr. Bert and Mr. Davis. Each of the brothers is liable for rent in the boarding house (a...

  19. 47 CFR 97.509 - Administering VE requirements.

    Science.gov (United States)

    2010-10-01

    ..., grandchildren, stepchildren, parents, grandparents, stepparents, brothers, sisters, stepbrothers, stepsisters... accommodate an examinee whose physical disabilities require a special examination procedure. The administering VEs may require a physician's certification indicating the nature of the disability before determining...

  20. 38 CFR 21.374 - Authorization for travel of attendants.

    Science.gov (United States)

    2010-07-01

    ... severity of the veteran's disability. Attendants may only be used to enable a veteran to attend... or marriage is the veteran's (i) Spouse, (ii) Parent, (iii) Child, (iv) Brother, (v) Sister, (vi...

  1. 20 CFR 410.623 - Reconsideration; right to reconsideration.

    Science.gov (United States)

    2010-04-01

    ... AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Determinations of Disability, Other... reconsideration is filed, as provided in § 410.624, by an individual as a widow, child, parent, brother, sister...

  2. To determine whether first-degree male relatives of women with polycystic ovary syndrome are at higher risk of developing cardiovascular disease and type II diabetes mellitus.

    Science.gov (United States)

    Hunter, A; Vimplis, S; Sharma, A; Eid, N; Atiomo, W

    2007-08-01

    The aim of this study was to determine whether first-degree male relatives of women with polycystic ovary syndrome (PCOS) were at increased risk of cardiovascular disease (CVD) and diabetes mellitus (type II DM). In a cross-sectional study, 60 women with PCOS and 112 controls were given a questionnaire. The prevalence of heart disease, stroke, diabetes and associated risk factors among fathers and brothers of women with PCOS and controls, were measured. The percentage of women with PCOS with at least one brother with a risk factor for CVD was 47.5%, around twice that seen in control women (24.71%). The prevalence of heart disease, stroke and diabetes were similar in brothers of women with PCOS and controls. In conclusion, brothers of women with PCOS may be at increased risk of CVD. They form an easily identified group, which can be targeted for primary prevention.

  3. Understanding Adolescent Delinquency: The Role of Older Siblings’ Delinquency and Popularity with Peers

    Science.gov (United States)

    Craine, Jessica L.; Tanaka, Teri A.; Nishina, Adrienne; Conger, Katherine J.

    2009-01-01

    The present study examined delinquency concordance and the moderating effects of younger sibling perceptions of older sibling popularity in a sample of 587 adolescent sibling pairs. Using a social learning framework, and taking dyad composition into account, perceptions of popularity were hypothesized to strengthen siblings’ concordance for delinquency. Older sibling delinquency significantly predicted younger sibling delinquency. Older sibling popularity was not important in predicting boys’ delinquency. However, perceptions of older sibling popularity directly predicted reduced delinquency for girls with older sisters. A significant interaction effect was found for girls with older brothers. Older brother delinquency predicted girls’ delinquency for girls who perceived their older brother to be relatively popular. There was no delinquency concordance for girls who perceived their older brothers to be less popular. PMID:20305731

  4. Detection of combined genomic variants in a Jordanian family with ...

    Indian Academy of Sciences (India)

    2Department of Surgery, Faculty of Medicine, University of Jordan, Amman 11942, Jordan ... brothers with sub-clinical hyperthyroidism, and their father were heterozygous ... Journal of Genetics, Vol. ..... However, further investigations should.

  5. Multiple Sclerosis, Personal Stories | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Multiple Sclerosis Personal Stories: Nicole Lemelle, Iris Young, Michael Anthony, ... something quite different for a person living with multiple sclerosis, such as his girlfriend's brother, Chuy. The more ...

  6. Rapitav sõna : Igakuine hip-hopi infopunkt / Kozy

    Index Scriptorium Estoniae

    Kozy, pseud.

    1999-01-01

    Uutest heliplaatidest Snoop Dogg "No Limit Top Dogg", Public Enemy "There's A Poison Goin" On"", RZA "Hits", Missy Misdemeanor Elliott "Da Real World", Insane Clown Posse "The Amazing Jeckel Brothers"

  7. Severe mental deficiency, proportionate dwarfism, and delayed sexual maturation. A distinct inherited syndrome.

    Science.gov (United States)

    Cantú, J M; Sánchez-Corona, J; García-Cruz, D; Fragoso, R

    1980-01-01

    Two 46,XY brothers were found to have a previously undescribed syndrome characterized by severe mental deficiency, proportionate dwarfism, and delayed sexual development. A recessive mode of inheritance, either autosomal or X-linked, is assumed.

  8. Rachel Jewkes

    African Journals Online (AJOL)

    different types of victims. Asked about motivations, men indicated that rape most commonly stemmed ... media campaigns such as 'Brothers for Life' and. 'One Man Can'. ..... of socialisation into a very violent, accentuated masculinity of a type.

  9. Langenud Gorilla / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 8-9. USA investeerimispanga Lehman Brothers tegevjuhist Dick Fuldist. Vt. samas: Richard S. Fuld: CV; Ameerika unistuste täitja: vendade investeerimispank; Taust; Kommenteerivad: Madis Toomsalu ja Jonathan Well

  10. Plaadid / Heili Vaus-Tamm

    Index Scriptorium Estoniae

    Vaus-Tamm, Heili, 1961-

    2003-01-01

    Uutest plaatidest Andras Schiff "Goldberg Variations", Yes "Remixes", "Chill: Brasil 2", "The Fighting Temptations soundtrack", Wheatus "Hand Over Your Loved Ones", Peaches "Fatherfucker", Chemical Brothers "Singles 93-03"

  11. Fabry's Disease: Case Series and Review of Literature

    African Journals Online (AJOL)

    Subsequent enzymatic and pedigree analysis confirmed the diagnosis of FD in the recipient and one of his brothers with the possibility of their mother ... enzyme levels and are being planned for treatment with enzyme replacement therapy ...

  12. I Remember Highlander

    Science.gov (United States)

    Williams-Hawkins, Maria

    2016-01-01

    "I Remember Highlander" reflects on the life choices of Marion Barry and Herman Henning Jr., fraternity brothers who sought the same goal but took different paths. The essay examines cultural and family situations that shaped lives and decisions.

  13. What Is Cardiomyopathy?

    Science.gov (United States)

    ... underlying conditions, such as diabetes and high blood pressure . Cardiomyopathy often runs in families. Your doctor may suggest that your parents, brothers and sisters, and children get checked to see whether they have the ...

  14. Uued plaadid

    Index Scriptorium Estoniae

    1999-01-01

    Uutest heliplaatidest Ivo Linna & Rock Hotel "Kõva ketas", Hendrik Sal-Saller "1994-1996", Chemical Brothers "Surrender", Mike & The Mechanics "M6", Bomfunk Mc"s "In Stereo", Jamiroquai "Synkronized"

  15. Brain Aneurysm: Early Detection and Screening

    Science.gov (United States)

    ... who has two or more relatives (e.g. mother, father, brother, sister, aunt, uncle, grandparent, cousins) with ... Harvey Memorial Chair of Research Kristen’s Legacy of Love Chair of Research TeamCindy Alcatraz Chair of Research ...

  16. Possible X linked congenital mitochondrial cardiomyopathy in three families.

    OpenAIRE

    Orstavik, K H; Skjörten, F; Hellebostad, M; Hågå, P; Langslet, A

    1993-01-01

    Familial cases of childhood congestive cardiomyopathy with X linked recessive inheritance and abnormalities of heart muscle mitochondria have been previously reported. We report here three families with possible X linked congestive cardiomyopathy and specific mitochondrial abnormalities. The heart disorder presented as endocardial fibroelastosis with neonatal death in two brothers in one family, and as heart failure and death in infancy in two brothers in the other two families. In one family...

  17. Siblings of Adults with Intellectual Disabilities: Their Perspectives On Guardianship and Its Alternatives

    OpenAIRE

    Brady, Anna M.

    2017-01-01

    Adult siblings of people with intellectual and developmental disabilities (IDD) are often on the front lines of supporting their brothers and sisters with IDD through caregiving and guardianship roles after their parents pass away. However, these siblings are often uninformed or under informed about ways that they can support their brothers and sisters. This study had the following three purposes: to determine what adult siblings of adults with IDD know about guardianship and its alternatives...

  18. Fraternal Birth Order, Family Size, and Male Homosexuality: Meta-Analysis of Studies Spanning 25 Years.

    Science.gov (United States)

    Blanchard, Ray

    2018-01-01

    The fraternal birth order effect is the tendency for older brothers to increase the odds of homosexuality in later-born males. This study compared the strength of the effect in subjects from small versus large families and in homosexual subjects with masculine versus feminine gender identities. Meta-analyses were conducted on 30 homosexual and 30 heterosexual groups from 26 studies, totaling 7140 homosexual and 12,837 heterosexual males. The magnitude of the fraternal birth order effect was measured with a novel variable, the Older Brothers Odds Ratio, computed as (homosexuals' older brothers ÷ homosexuals' other siblings) ÷ (heterosexuals' older brothers ÷ heterosexuals' other siblings), where other siblings = older sisters + younger brothers + younger sisters. An Older Brothers Odds Ratio of 1.00 represents no effect of sexual orientation; values over 1.00 are positive evidence for the fraternal birth order effect. Evidence for the reliability of the effect was consistent. The Older Brothers Odds Ratio was significantly >1.00 in 20 instances, >1.00 although not significantly in nine instances, and nonsignificantly <1.00 in 1 instance. The pooled Older Brothers Odds Ratio for all samples was 1.47, p < .00001. Subgroups analyses showed that the magnitude of the effect was significantly greater in the 12 feminine or transgender homosexual groups than in the other 18 homosexual groups. There was no evidence that the magnitude of the effect differs according to family size.

  19. The 48, XXXX/49,XXXXY/49,XXXX,i(Yq) mosaicism in a 3-year-old boy from a twin pregnancy.

    Science.gov (United States)

    Kaluzewski, B; Podkul, D; Zaborowska, I; Moruzgala, T; Jakubowski, L

    1977-07-26

    A 3-year-old boy from twin pregnancy with the features of marked dystrophia from birth, deficient growth, considerable retardation of physical and mental development, numerous somatic defects, suspected congenital heart disease, and hypoplastic external genitalia, is reported. The 48,XXXX/49,XXXXY/49,XXXX,i(Yq) karyotype was diagnosed. The boy's brother, normally developed, had a 46,XY karyotype. It was found on the basis of serologic findings that the brothers were dizygotic twins.

  20. United States Security Policy Implications of a Post-Fidel Cuba

    Science.gov (United States)

    2012-03-10

    paternalism .8 Even Cuba’s first president was complicit when he negotiated a perpetual lease for Guantanamo Naval 4 Base that made a sham of...diplomatic alliances, and even the health of Fidel Castro. Most recently, the succession of the authoritarian dictatorship from brother to brother...controlled within an authoritarian regime. 26 Undoubtedly, Raúl Castro appreciates the benefits of a model of “patrimonial authoritarianism , or economic