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Sample records for broodstock programs depends

  1. "The Success of Captive Broodstock Programs Depends on High In-Culture Survival, ..." [from the Abstract], 2006-2007 Progress Report.

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    Berejikian, Barry A. [National Marine Fisheries Service

    2009-04-08

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. Accomplishments detailed in this report are listed below by major objective. Objective 1: This study documented that captively reared Chinook exhibited spawn timing similar to their founder anadromous population. An analysis of spawn timing data of captively reared Chinook salmon that had received different levels of antibiotic treatment did not suggest that antibiotic treatments during the freshwater or seawater phase of the life cycle affects final maturation timing. No effect of rearing density was found with respect to spawn timing or other reproductive behaviors. Objective 2: This study investigated the critical period(s) for imprinting for sockeye salmon by exposing juvenile salmon to known odorants at key developmental stages. Molecular assessments of imprinting-induced changes in odorant receptor gene expression indicated that regulation of odorant expression differs between coho and sockeye salmon. While temporal patterns differ between these species, exposure to arginine elicited increases in odorant receptor mRNA expression in sockeye salmon. Objective 3: This study: (i) identified the critical period when maturation is initiated in male spring Chinook salmon and when body growth affects onset of puberty, (ii) described changes in the reproductive endocrine system during onset of puberty and throughout spermatogenesis in male spring Chinook salmon, (iii) found that the rate of oocyte development prior to vitellogenesis is related to body growth in female spring Chinook, and (iv) demonstrated that growth regimes which reduce early (age 2) male maturation slow the rate of primary and early

  2. Research on Captive Broodstock Programs for Pacific Salmon; Assessment of Captive Broodstock Technologies, Annual Report 2002-2003.

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    Berejikian, Barry

    2004-01-01

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. Current velocity in rearing vessels had little if any effect on reproductive behavior of captively reared steelhead. However, males and females reared in high velocity vessels participated a greater number of spawning events than siblings reared in low velocity tanks. Observations of nesting females and associated males in a natural stream (Hamma Hamma River) were consistent with those observed in a controlled spawning channel. DNA pedigree analyses did not reveal significant differences in the numbers of fry produced by steelhead reared in high and low velocity vessels. To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon are being exposed to known odorants at key developmental stages. Subsequently they will be tested for development of long-term memories of these odorants. In 2002-2003, the efficacy of EOG analysis for assessing imprinting was demonstrated and will be applied in these and other behavioral and molecular tools in the current work plan. Results of these experiments will be important to determine the critical periods for imprinting for the offspring of captively-reared fish destined for release into natal rivers or lakes. By early August, the oocytes of all of Rapid River Hatchery chinook salmon females returning from the ocean had advanced to the tertiary yolk globule stage; whereas, only some of the captively reared Lemhi River females sampled had advanced to this stage, and the degree of advancement was not dependent on rearing temperature. The mean spawning time of captive Lemhi River females was 3-4 weeks after that of the Rapid River fish

  3. Genetic variability of broodstocks of restocking programs in Brazil

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    Nelson Lopera-Barrero

    2015-09-01

    Full Text Available Objective. The aim of this study was evaluate the genetic diversity of the following broodstocks: piapara (Leporinus elongatus, dourado (Salminus brasiliensis, jundiá (Rhamdia quelen and cachara (Pseudoplatystoma fasciatum already useful for restocking programs in the Paranapanema, Iguaçu and Paraná Brazilian Rivers. Materials and methods. Samples from the caudal fin of 122 fish were analyzed. DNA was extracted by NaCl protocol. PCR products were separated by a horizontal agarose gel electrophoresis. The fragments were visualized by staining with ethidium bromide. Results. The amplification of 25 primers generated different fragments in studied species that allowed characterizing 440 fragments of 100-2900 bp. High percentage of polymorphic fragments (66.67 to 86.29, Shannon index (0.365 to 0.486 and genetic diversity of Nei (0.248 to 0.331 were detected. Conclusions. The level of genetic variability in the broodstocks was adequate for allowing their use in restocking programs in the studied Rivers. However, periodical monitoring studies of genetic variability in these stocks, the mating system, reproductive system and general management must be made to guarantee the preservation of wild populations.

  4. Research on Captive Broodstock Programs for Pacific Salmon, 2004-2005 Annual Report.

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    Berejikian, Barry A. (National Marine Fisheries Service)

    2005-11-01

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. Accomplishments detailed in this report and those since the last project review period (FY 2003) are listed below by major objective. Objective 1: (i) Developed tools for monitoring the spawning success of captively reared Chinook salmon that can now be used for evaluating the reintroduction success of ESA-listed captive broodstocks in their natal habitats. (ii) Developed an automated temperature controlled rearing system to test the effects of seawater rearing temperature on reproductive success of Chinook salmon. Objective 2: (i) Determined that Columbia River sockeye salmon imprint at multiple developmental stages and the length of exposure to home water is important for successful imprinting. These results can be utilized for developing successful reintroduction strategies to minimize straying by ESA-listed sockeye salmon. (ii) Developed behavioral and physiological assays for imprinting in sockeye salmon. Objective 3: (i) Developed growth regime to reduce age-two male maturation in spring Chinook salmon, (ii) described reproductive cycle of returning hatchery Snake River spring Chinook salmon relative to captive broodstock, and (iii) found delays in egg development in captive broodstock prior to entry to fresh water. (iv) Determined that loss of Redfish Lake sockeye embryos prior to hatch is largely due to lack of egg fertilization rather than embryonic mortality. Objective 4 : (i) Demonstrated safety and efficacy limits against bacterial kidney disease (BKD) in fall Chinook of attenuated R. salmoninarum vaccine and commercial vaccine Renogen, (ii) improved prophylactic and therapeutic

  5. Snake River sockeye salmon captive broodstock program: hatchery element: annual progress report, 2000.; ANNUAL

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    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Marine Fisheries Service at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Marine Fisheries Service are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases are also reported under separate cover. Captive broodstock program activities conducted between January 1, 2000 and December 31, 2000 are presented in this report

  6. Snake River Sockeye Salmon Captive Broodstock Program : Hatchery Element : Annual Progress Report, 2000.

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    Kline, Paul A.; Willard, Catherine

    2001-04-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Marine Fisheries Service at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Marine Fisheries Service are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases are also reported under separate cover. Captive broodstock program activities conducted between January 1, 2000 and December 31, 2000 are presented in this report.

  7. Research on Captive Broodstock Programs for Pacific Salmon, 2003-2004 Annual Report.

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    Berejikian, Barry A.; Athos, Jaime I.; Dittman, Andrew H. (National Marine Fisheries Service)

    2004-07-01

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. We were able to develop an analytical method for optimizing the detection of spawning events in Chinook salmon using EMG signals. The method developed essentially captured the consistently greater frequency of higher EMG values associated with females cover digging immediately following spawning. However, females implanted with EMG tags retained the majority of their eggs, which significantly reduced their reproductive success compared to non-tagged females. Future work will include increased sample sizes, and modified tagging methods to reduce negative effects on reproductive success. Upper Columbia River sockeye salmon exposed to the odorants PEA, L-threonine, Larginine and L-glutamate were able to learn and remember these odorants as maturing adults up to 2.5 years after exposure. These results suggest that the alevin and smolt stages are both important developmental periods for successful olfactory imprinting. Furthermore, the period of time that fish are exposed to imprinting odors may be important for successful imprinting. Experimental fish exposed to imprinting odors as smolts for six or one weeks successfully imprinted to these odors but imprinting could not be demonstrated in smolts exposed to odors for only one day. A 2-3 C reduction in seawater rearing temperature during the fall and winter prior to final maturation had little effect on reproductive development of spring Chinook salmon. Body size at spawning and total ovary mass were similar between temperature treatments. The percentage of fertilized eggs was significantly higher for females exposed to the ambient temperature compared

  8. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 1997 Annual Report.

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    Kline, Paul A.; Heindel, Jeff A.; Willard, Catherine (Idaho Department of Fish and Game, Boise, ID)

    2003-08-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Marine Fisheries Service at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Marine Fisheries Service are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases (annual report to the Bonneville Power Administration for the research element of the program) are also reported under separate cover. Captive broodstock program activities conducted between January 1, 1997 and December 31, 1997 are presented in this report. One hundred twenty-six female sockeye salmon from one captive broodstock group were spawned at the Eagle Fish Hatchery in 1997. Successful spawn pairings produced approximately 148,781 eyed-eggs with a cumulative mean survival to eyed-egg rate of 57.3%. Approximately 361,600 sockeye salmon were released to Sawtooth basin waters in 1997. Reintroduction strategies included eyed-eggs (brood year 1997), presmolts (brood year 1996), and prespawn adults for volitional spawning (brood year 1994). Release locations included Redfish Lake, Alturas Lake, and Pettit Lake. During this reporting period, four broodstocks and two unique production groups were in culture at the Eagle Fish Hatchery. Two of the four broodstocks were incorporated into the 1997 spawning design, and one broodstock was terminated following

  9. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 2001 Annual Report.

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    Kline, Paul A.; Willard, Catherine; Baker, Dan J. (Idaho Department of Fish and Game, Boise, ID)

    2003-08-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Marine Fisheries Service at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Marine Fisheries Service are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases (annual report to the Bonneville Power Administration for the research element of the program) are also reported separately. Captive broodstock program activities conducted between January 1, 2001 and December 31, 2001 for the hatchery element of the program are presented in this report. In 2001, 26 anadromous sockeye salmon returned to the Sawtooth Basin. Twenty-three of these adults were captured at adult weirs located on the upper Salmon River and on Redfish Lake Creek. Three of the anadromous sockeye salmon that returned were observed below the Sawtooth Fish Hatchery weir and allowed to migrate upstream volitionally (following the dismantling of the weir on October 12, 2001). Nine anadromous adults were incorporated into the captive broodstock program spawning design in 2001. The remaining adults were released to Redfish Lake for natural spawning. Based on their marks, returning adult sockeye salmon originated from a variety of release options. Two sockeye salmon females from the anadromous group and 152 females from the brood year 1998 captive

  10. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 1999 Annual Report.

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    Baker, Dan J,; Heindel, Jeff A.; Kline, Paul A. (Idaho Department of Fish and Game, Boise, ID)

    2005-08-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Marine Fisheries Service at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Marine Fisheries Service are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases are also reported under separate cover. Captive broodstock program activities conducted between January 1, 1999 and December 31, 1999 are presented in this report. In 1999, seven anadromous sockeye salmon returned to the Sawtooth Valley and were captured at the adult weir located on the upper Salmon River. Four anadromous adults were incorporated in the captive broodstock program spawning design for year 1999. The remaining three adults were released to Redfish Lake for natural spawning. All seven adults were adipose and left ventral fin-clipped, indicating hatchery origin. One sockeye salmon female from the anadromous group and 81 females from the captive broodstock group were spawned at the Eagle Fish Hatchery in 1999. Spawn pairings produced approximately 63,147 eyed-eggs with egg survival to eyed-stage of development averaging 38.97%. Eyed-eggs (20,311), presmolts (40,271), smolts (9,718), and adults (21) were planted or released into Sawtooth Valley waters in 1999. Supplementation strategies involved releases to Redfish Lake, Redfish Lake Creek

  11. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 2002 Annual Report.

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    Willard, Catherine; Baker, Dan J.; Heindel, Jeff A. (Idaho Department of Fish and Game, Boise, ID)

    2003-12-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Oceanic and Atmospheric Administration at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Oceanic and Atmospheric Administration are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases (annual report to the Bonneville Power Administration for the research element of the program) are also reported separately. Captive broodstock program activities conducted between January 1, 2002 and December 31, 2002 for the hatchery element of the program are presented in this report. n 2002, 22 anadromous sockeye salmon returned to the Sawtooth Valley. Fifteen of these adults were captured at adult weirs located on the upper Salmon River and on Redfish Lake Creek. Seven of the anadromous sockeye salmon that returned were observed below the Sawtooth Fish Hatchery weir and allowed to migrate upstream volitionally (following the dismantling of the weir on September 30, 2002). All adult returns were released to Redfish Lake for natural spawning. Based on their marks, returning adult sockeye salmon originated from a variety of release options. Sixty-six females from brood year 1999 and 28 females from brood year 2000 captive broodstock groups were spawned at the Eagle Hatchery in 2002. Spawn pairings produced approximately 65

  12. Grande Ronde Basin Spring Chinook Salmon Captive Broodstock Program, 2008 Annual Report.

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    Hoffnagle, Timothy L.; Hair, Donald; Gee, Sally

    2009-03-31

    wherever possible. We continue to have difficulty with prevention and treatment of BKD outbreaks and continue to use erythromycin and azithromycin to treat this disease. We are also continuing to investigate other possible treatments and prophylactic measures. To reduce the incidence of BKD in offspring of the Captive Broodstock Program, we continue to allow culling of eyed eggs from females with high BKD ELISA values (generally >0.800 OD units but the cull level varies annually, depending on the distribution of ELISA values, number of eggs collected, and management considerations). We are also using ultrasound to determine maturity and sex of fish early in the maturation process and are now able to determine maturity and sex of most maturing fish in early April. This allows us to transfer maturing fish from saltwater to freshwater at a more natural time, which should improve fecundity and egg quality of saltwater-reared fish.

  13. Research on Captive Broodstock Programs for Pacific Salmon, 2001-2002 Annual Report.

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    Berejikian, Barry; Tezak, E.; Endicott, Rick

    2002-08-01

    The efficacy of captive broodstock programs depends on high in-culture survival and the fitness of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. The following summarizes some of the work performed and results from the FY 2001 performance period: (1) The incidence of male maturation of age-1 chinook salmon was significantly reduced by reducing growth in the first year of rearing. (2) Experimentally manipulated growth rates of captively-reared coho salmon had significant effects on female maturation rate, egg size, and fecundity, and the effects were stage-specific (i.e., pre-smolt vs. post-smolt). (3) A combination of Renogen and MT239 vaccination of yearling chinook salmon given an acute R. salmoninarum challenge had a significantly longer survival time than the mock-vaccinated group. The survival time was marginally higher than was seen in acutely challenged fish vaccinated with either Renogen or MT239 alone and suggests that a combination vaccine of Renogen and MT239 may be useful as both a prophylactic and therapeutic agent against BKD. (4) Full-sib (inbred) groups of chinook salmon have thus far exhibited lower ocean survival than half-sib and non-related groups. Effects of inbreeding on fluctuating asymmetry did not follow expected patterns. (5) Sockeye salmon were exposed to specific odorants at either the alevin/emergent fry stage or the smolt stage to determine the relative importance of odorant exposure during key developmental periods and the importance of exposure duration. (6) Experimental studies to determine the effects of exercise conditioning on steelhead reproductive behavior and the effects of male body size on chinook salmon fertilization success during natural spawning were completed.

  14. Snake River Sockeye Salmon Captive Broodstock Program Hatchery Element : Project Progress Report 2007 Annual Report.

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    Baker, Dan J.; Heindel, Jeff A.; Green, Daniel G.; Kline, Paul A.

    2008-12-17

    Numbers of Snake River sockeye salmon Oncorhynchus nerka have declined dramatically in recent years. In Idaho, only the lakes of the upper Salmon River (Sawtooth Valley) remain as potential sources of production (Figure 1). Historically, five Sawtooth Valley lakes (Redfish, Alturas, Pettit, Stanley, and Yellowbelly) supported sockeye salmon (Bjornn et al. 1968; Chapman et al. 1990). Currently, only Redfish Lake receives a remnant anadromous run. On April 2, 1990, the National Oceanic and Atmospheric Administration Fisheries Service (NOAA - formerly National Marine Fisheries Service) received a petition from the Shoshone-Bannock Tribes (SBT) to list Snake River sockeye salmon as endangered under the United States Endangered Species Act (ESA) of 1973. On November 20, 1991, NOAA declared Snake River sockeye salmon endangered. In 1991, the SBT, along with the Idaho Department of Fish & Game (IDFG), initiated the Snake River Sockeye Salmon Sawtooth Valley Project (Sawtooth Valley Project) with funding from the Bonneville Power Administration (BPA). The goal of this program is to conserve genetic resources and to rebuild Snake River sockeye salmon populations in Idaho. Coordination of this effort is carried out under the guidance of the Stanley Basin Sockeye Technical Oversight Committee (SBSTOC), a team of biologists representing the agencies involved in the recovery and management of Snake River sockeye salmon. National Oceanic and Atmospheric Administration Fisheries Service ESA Permit Nos. 1120, 1124, and 1481 authorize IDFG to conduct scientific research on listed Snake River sockeye salmon. Initial steps to recover the species involved the establishment of captive broodstocks at the Eagle Fish Hatchery in Idaho and at NOAA facilities in Washington State (for a review, see Flagg 1993; Johnson 1993; Flagg and McAuley 1994; Kline 1994; Johnson and Pravecek 1995; Kline and Younk 1995; Flagg et al. 1996; Johnson and Pravecek 1996; Kline and Lamansky 1997; Pravecek and

  15. Research on Captive Broodstock Programs for Pacific Salmon, 2002-2003 Annual Report.

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    Berejikian, Barry A. (National Marine Fisheries Service)

    2004-01-01

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. Current velocity in rearing vessels had little if any effect on reproductive behavior of captively reared steelhead. However, males and females reared in high velocity vessels participated a greater number of spawning events than siblings reared in low velocity tanks. Observations of nesting females and associated males in a natural stream (Hamma Hamma River) were consistent with those observed in a controlled spawning channel. DNA pedigree analyses did not reveal significant differences in the numbers of fry produced by steelhead reared in high and low velocity vessels. To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon are being exposed to known odorants at key developmental stages. Subsequently they will be tested for development of long-term memories of these odorants. In 2002-2003, the efficacy of EOG analysis for assessing imprinting was demonstrated and will be applied in these and other behavioral and molecular tools in the current work plan. Results of these experiments will be important to determine the critical periods for imprinting for the offspring of captively-reared fish destined for release into natal rivers or lakes. By early August, the oocytes of all of Rapid River Hatchery chinook salmon females returning from the ocean had advanced to the tertiary yolk globule stage; whereas, only some of the captively reared Lemhi River females sampled had advanced to this stage, and the degree of advancement was not dependent on rearing temperature. The mean spawning time of captive Lemhi River females was 3-4 weeks after that of the Rapid River fish

  16. Tucannon River Spring Chinook Salmon Captive Broodstock Program, Annual Report 2001.

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    Gallinat, Michael P.; Bumgarner, Joseph D.

    2002-05-01

    This report summarizes the objectives, tasks, and accomplishments of the Tucannon River spring chinook captive brood during 2001. The WDFW initiated a captive broodstock program in 1997. The overall goal of the Tucannon River captive broodstock program is for the short-term, and eventually long-term, rebuilding of the Tucannon River spring chinook salmon run, with the hope that natural production will sustain itself. The project goal is to rear captive salmon selected from the supplementation program to adults, spawn them, rear their progeny, and release approximately 150,000 smolts annually into the Tucannon River between 2003-2007. These smolt releases, in combination with the current hatchery supplementation program (132,000 smolts) and wild production, are expected to produce 600-700 returning adult spring chinook to the Tucannon River each year from 2005-2010. The captive broodstock program will collect fish from five (1997-2001) brood years (BY). The captive broodstock program was initiated with 1997 BY juveniles, and the 2001 BY fish have been selected. As of Jan 1, 2002, WDFW has 17 BY 1997, 159 BY 1998, 316 BY 1999, 448 BY 2000, and approximately 1,200 BY 2001 fish on hand at LFH. The 2001 eggtake from the 1997 brood year (Age 4) was 233,894 eggs from 125 ripe females. Egg survival was 69%. Mean fecundity based on the 105 fully spawned females was 1,990 eggs/female. The 2001 eggtake from the 1998 brood year (Age 3) was 47,409 eggs from 41 ripe females. Egg survival was 81%. Mean fecundity based on the 39 fully spawned females was 1,160 eggs/female. The total 2001 eggtake from the captive brood program was 281,303 eggs. As of May 1, 2002 we have 171,495 BY 2001 captive brood progeny on hand. A total of 20,592 excess fish were marked as parr (AD/CWT) and will be released during early May, 2002 into the Tucannon River (rkm 40-45). This will allow us to stay within our maximum allowed number (150,000) of smolts released. During April 2002, WDFW volitionally

  17. Tucannon River Spring Chinook Salmon Captive Broodstock Program, Annual Report 2002.

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    Gallinat, Michael; Varney, Michelle

    2003-05-01

    This report summarizes the objectives, tasks, and accomplishments of the Tucannon River Spring Chinook Captive Broodstock Program during 2002. The WDFW initiated a captive broodstock program in 1997. The overall goal of the Tucannon River captive broodstock program is for the short-term, and eventually long-term, rebuilding of the Tucannon River spring chinook salmon run, with the hope that natural production will sustain itself. The project goal is to rear captive salmon selected from the supplementation program to adults, spawn them, rear their progeny, and release approximately 150,000 smolts annually into the Tucannon River between 2003-2007. These smolt releases, in combination with the current hatchery supplementation program (132,000 smolts) and wild production, are expected to produce 600-700 returning adult spring chinook to the Tucannon River each year from 2005-2010. The captive broodstock program collected fish from five (1997-2001) brood years (BY). As of January 1, 2003, WDFW has approximately 11 BY 1998, 194 BY 1999, 314 BY 2000, 447 BY 2001, and 300 BY 2002 (for extra males) fish on hand at LFH. The 2002 eggtake from the 1997 brood year (Age 5) was 13,176 eggs from 10 ripe females. Egg survival was 22%. Mean fecundity based on the 5 fully spawned females was 1,803 eggs/female. The 2002 eggtake from the 1998 brood year (Age 4) was 143,709 eggs from 93 ripe females. Egg survival was 29%. Mean fecundity based on the 81 fully spawned females was 1,650 eggs/female. The 2002 eggtake from the 1999 brood year (Age 3) was 19,659 eggs from 18 ripe females. Egg survival was 55%. Mean fecundity based on the 18 fully spawned fish was 1,092 eggs/female. The total 2002 eggtake from the captive brood program was 176,544 eggs. A total of 120,833 dead eggs (68%) were removed with 55,711 live eggs remaining for the program. As of May 1, 2003 we had 46,417 BY 2002 captive brood progeny on hand A total of 20,592 excess BY 01 fish were marked as parr (AD/CWT) and

  18. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 1998 Annual Progress Report.

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    Kline, Paul A.; Heindel, Jeff A.

    1999-12-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and NMFS initiated efforts to conserve and rebuild populations in Idaho. Captive broodstock program activities conducted between January 1, 1998 and December 31, 1998, are presented in this report.

  19. Snake River Sockeye Salmon Captive Broodstock Program; Hatchery Element, 2004 Annual Report.

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    Baker, Dan J.; Heindel, Jeff A.; Redding, Jeremy (Idaho Department of Fish and Game, Boise, ID)

    2006-05-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and the National Marine Fisheries Service initiated efforts to conserve and rebuild populations in Idaho. Initial steps to recover sockeye salmon included the establishment of a captive broodstock program at the Idaho Department of Fish and Game Eagle Fish Hatchery. Sockeye salmon broodstock and culture responsibilities are shared with the National Oceanic and Atmospheric Administration at two locations adjacent to Puget Sound in Washington State. Activities conducted by the Shoshone-Bannock Tribes and the National Oceanic and Atmospheric Administration are reported under separate cover. Idaho Department of Fish and Game monitoring and evaluation activities of captive broodstock program fish releases (annual report to the Bonneville Power Administration for the research element of the program) are also reported separately. Captive broodstock program activities conducted between January 1, 2004 and December 31, 2004 for the hatchery element of the program are presented in this report. In 2004, twenty-seven anadromous sockeye salmon returned to the Sawtooth Valley. Traps on Redfish Lake Creek and the upper Salmon River at the Sawtooth Fish Hatchery intercepted one and four adults, respectively. Additionally, one adult sockeye salmon was collected at the East Fork Salmon River weir, 18 were seined from below the Sawtooth Fish Hatchery weir, one adult sockeye salmon was observed below the Sawtooth Fish Hatchery weir but not captured, and two adult sockeye salmon were observed in Little Redfish Lake but not captured. Fish were captured/collected between July 24 and September 14, 2004. The captured/collected adult sockeye salmon (12 females and 12 males) originated from a variety of release strategies and were transferred to

  20. Tucannon River Spring Chinook Captive Broodstock Program Final Environmental Assessment and Finding of No Significant Impact

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2000-05-24

    Bonneville Power Administration (BPA) is proposing to fund the Tucannon River Spring Chinook Captive Broodstock Program, a small-scale production initiative designed to increase numbers of a weak but potentially recoverable population of spring chinook salmon in the Tucannon River in the State of Washington. BPA has prepared an Environmental Assessment (EA) (DOE/EA-l326) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and BPA is issuing this Finding of No Significant Impact (FONSI).

  1. Research on Captive Broodstock Programs for Pacific Salmon, 2001-2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Berejikian, Barry A.; Tezak, E.P. (National Marine Fisheries Service); Endicott, Rick (Long Live the Kings, Seattle, WA)

    2002-08-01

    In the 2000 Federal Columbia River Power System (FCRPS) Biological Opinion, NMFS identified six populations of steelhead and several salmon populations that had dropped to critically low levels and continue to decline. Following thorough risk-benefit analyses, captive propagation programs for some or all of the steelhead (Oncorhynchus mykiss) populations may be required to reduce the risk of extinction, and more programs may be required in the future. Thus, captive propagation programs designed to maintain or rebuild steelhead populations require intensive and rigorous scientific evaluation, much like the other objectives of BPA Project 1993-056-00 currently underway for chinook (O. tshawytscha) and sockeye salmon (O. nerka). Pacific salmon reared to the adult stage in captivity exhibit poor reproductive performance when released to spawn naturally. Poor fin quality and swimming performance, incomplete development of secondary sex characteristics, changes in maturation timing, and other factors may contribute to reduced spawning success. Improving natural reproductive performance is critical for the success of captive broodstock programs in which adult-release is a primary reintroduction strategy for maintaining ESA-listed populations.

  2. Snake River sockeye salmon captive broodstock program hatchery element, Annual Progress Report: January 1, 1998 - December 31, 1998

    International Nuclear Information System (INIS)

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon as endangered under the Endangered Species Act of 1973. In 1991, the Idaho Department of Fish and Game, the Shoshone-Bannock Tribes, and NMFS initiated efforts to conserve and rebuild populations in Idaho. Captive broodstock program activities conducted between January 1, 1998 and December 31, 1998, are presented in this report

  3. Snake River Sockeye Salmon Captive Broodstock Program Research Elements : 2007 Annual Project Progess Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, Mike; Plaster, Kurtis; Redfield, Laura; Heindel, Jeff; Kline, Paul

    2008-12-17

    On November 20, 1991, the National Oceanic Atmospheric Administration listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Shoshone-Bannock Tribes (SBT) and Idaho Department of Fish and Game (IDFG) initiated the Snake River Sockeye Salmon Captive Broodstock Program to conserve and rebuild populations in Idaho. Restoration efforts are focused on Redfish, Pettit, and Alturas lakes within the Sawtooth Valley. The first release of hatchery-produced adults occurred in 1993. The first release of juvenile sockeye salmon from the captive broodstock program occurred in 1994. In 1999, the first anadromous adult returns from the captive broodstock program were recorded when six jacks and one jill were captured at the IDFG Sawtooth Fish Hatchery. In 2007, progeny from the captive broodstock program were released using four strategies: (1) eyed-eggs were planted in Pettit Lake in November; (2) age-0 presmolts were released to Alturas, Pettit, and Redfish lakes in October; (3) age-1 smolts were released into Redfish Lake Creek and the upper Salmon River in May; and (4) hatchery-produced adult sockeye salmon were released to Redfish Lake for volitional spawning in September. Oncorhynchus nerka population monitoring was conducted on Redfish, Alturas, and Pettit lakes using a midwater trawl in September 2007. Population abundances were estimated at 73,702 fish for Redfish Lake, 124,073 fish for Alturas Lake, and 14,746 fish for Pettit Lake. Angler surveys were conducted from May 26 through August 7, 2007 on Redfish Lake to estimate kokanee harvest. On Redfish Lake, we interviewed 102 anglers and estimated that 56 kokanee were harvested. The calculated kokanee catch rate was 0.03 fish/hour for each kokanee kept. The juvenile out-migrant trap on Redfish Lake Creek was operated from April 14 to June 13, 2007. We estimated that 5,280 natural origin and 14,256 hatchery origin sockeye salmon smolts out-migrated from

  4. Snake River Sockeye Salmon Captive Broodstock Program; Research Element, 2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Willard, Catherine; Plaster, Kurtis; Castillo, Jason (Idaho Department of Fish and Game, Boise, ID)

    2005-01-01

    On November 20, 1991, the National Oceanic Atmospheric Administration listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Shoshone-Bannock Tribes (SBT) and Idaho Department of Fish and Game (IDFG) initiated the Snake River Sockeye Salmon Captive Broodstock Program to conserve and rebuild populations in Idaho. Restoration efforts are focused on Redfish, Pettit, and Alturas lakes within the Sawtooth Valley. The first release of hatchery-produced adults occurred in 1993. The first release of juvenile sockeye salmon from the captive broodstock program occurred in 1994. In 1999, the first anadromous adult returns from the captive broodstock program were recorded when six jacks and one jill were captured at the IDFG Sawtooth Fish Hatchery. In 2003, progeny from the captive broodstock program were released using three strategies: eyed-eggs were planted in Pettit and Alturas lakes in November and December, age-0 presmolts were released to Alturas, Pettit, and Redfish lakes in October, and hatchery-produced adult sockeye salmon were released to Redfish Lake for volitional spawning in September. Oncorhynchus nerka population monitoring was conducted on Redfish, Alturas, and Pettit lakes using a midwater trawl in September 2003. Age-0 through age-4 O. nerka were captured in Redfish Lake, and population abundance was estimated at 81,727 fish. Age-0 through age-3 O. nerka were captured in Alturas Lake, and population abundance was estimated at 46,234 fish. Age-0 through age-3 O. nerka were captured in Pettit Lake, and population abundance was estimated at 11,961 fish. Angler surveys were conducted from May 25 through August 7, 2003 on Redfish Lake to estimate kokanee harvest. On Redfish Lake, we interviewed 179 anglers and estimated that 424 kokanee were harvested. The calculated kokanee catch rate was 0.09 fish/hour. The juvenile out-migrant trap on Redfish Lake Creek was operated from April 15 to May 29

  5. Grande Ronde Basin Spring Chinook Salmon Captive Broodstock Program, 1995-2002 Summary Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hoffnagle, Timothy; Carmichael, Richard; Noll, William

    2003-12-01

    survey areas in 1995 from as high as 1,205 redds in the same area in 1969 (Table 1). All streams reached low points (0-6 redds in the index areas) in the 1990's, except those in which no redds were found for several years and surveys were discontinued, such as Spring, Sheep and Indian creeks which had a total of 109 redds in 1969. The Minam and Wenaha rivers are tributaries of the Grande Ronde River located primarily in wilderness areas. Chinook salmon numbers in these two streams (based on redd counts) also decreased dramatically beginning in the early 1970's (Table 1). Since then there have been a few years of increasing numbers of redds but counts have generally been 25-40% of the number seen in the 1960's. No hatchery fish have been released into either of these streams and we monitor them during spawning ground surveys for the presence of hatchery strays. These populations will be used as a type of control for evaluating our supplementation efforts in Catherine Creek, upper Grande Ronde River and Lostine River. In this way, we can attempt to filter out the effects of downstream variables, over which we have no control, when we interpret the results of the captive broodstock program as the F1 and F2 generations spawn and complete their life cycles in the wild. The Grande Ronde Basin Captive Broodstock Program was initiated because these chinook salmon populations had reached critical levels where dramatic and unprecedented efforts were needed to prevent extinction and preserve any future options for use of endemic fish for artificial propagation programs for recovery and mitigation. This program was designed to quickly increase numbers of returning adults, while maintaining the genetic integrity of each endemic population.

  6. Development of giant freshwater prawn broodstock

    OpenAIRE

    Mohanta, K.N.

    2000-01-01

    The commercial success of a giant freshwater prawn (Macrobrachium rosenbergii) hatchery depends upon the uninterrupted supply of the desired quantity and quality of broodstock. This study was an attempt to develop the broodstock near a hatchery, to be used for seed production throughout the year. The hatchery produced seed were stocked at the rate of 3/m2 after initial pond preparation. The prawns were fed with a pelleted diet (3 mm size) prepared by using locally available feed ingredients. ...

  7. "Research to Improve the Efficacy of Captive Broodstock Programs and Advance Hatchery Reform Throughout the Columbia River Basin." [from the Abstract], 2007-2008 Annual Progress Report.

    Energy Technology Data Exchange (ETDEWEB)

    Berejikian, Barry A. [National Marine Fisheries Service

    2009-04-08

    This project was developed to conduct research to improve the efficacy of captive broodstock programs and advance hatchery reform throughout the Columbia river basin. The project has three objectives: (1) maintain adaptive life history characteristics in Chinook salmon, (2) improve imprinting in juvenile sockeye salmon, and (3) match wild phenotypes in Chinook and sockeye salmon reared in hatcheries. A summary of the results are as follows: Objective 1: Adult and jack Chinook salmon males were stocked into four replicate spawning channels at a constant density (N = 16 per breeding group), but different ratios, and were left to spawn naturally with a fixed number of females (N = 6 per breeding group). Adult males obtained primary access to females and were first to enter the nest at the time of spawning. Jack male spawning occurred primarily by establishing satellite positions downstream of the courting pair, and 'sneaking' into the nest at the time of spawning. Male dominance hierarchies were fairly stable and strongly correlated with the order of nest entry at the time of spawning. Spawning participation by jack and adult males is consistent with a negative frequency dependent selection model, which means that selection during spawning favors the rarer life history form. Results of DNA parentage assignments will be analyzed to estimate adult-to-fry fitness of each male. Objective 2: To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon were exposed to known odorants at key developmental stages. Molecular assessments of imprinting-induced changes in odorant receptor gene expression indicated that regulation of odorant expression is influenced by developmental status and odor exposure history. The results suggest that sockeye salmon are capable of imprinting to homing cues during the developmental periods that correspond to several of current release strategies employed as part of the Captive Broodstock program

  8. Production Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. Information on the number of smolts received into the program is...

  9. Fish Health Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. All fresh mortalities larger than 100 mm are sent to Fish Health for...

  10. Fish Culture Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. Raw data on rearing density, loading density, water temperature, ration,...

  11. Broodyear Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. Data is collected by broodyear on % survival to adult, % maturity as two...

  12. Growth Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. The fork length to the nearest mm and weight to the nearest gram of a...

  13. "Research to Improve the Efficacy of Captive Broodstock Programs and Advance Hatchery Reform Throughout the Columbia River Basin." [from the Abstract], 2008-2009 Progress Report.

    Energy Technology Data Exchange (ETDEWEB)

    Berejikian, Barry A. [National Oceanic and Atmospheric Administration, National Marine Fisheries Service

    2009-08-18

    This project was developed to conduct research to improve the efficacy of captive broodstock programs and advance hatchery reform throughout the Columbia River Basin. The project has three objectives: (1) maintain adaptive life history characteristics in Chinook salmon, (2) improve imprinting in juvenile sockeye salmon, and (3) match wild phenotypes in Chinook and sockeye salmon reared in hatcheries. A summary of the results are as follows: Objective 1: The ratio of jack to adult male Chinook salmon were varied in experimental breeding populations to test the hypothesis that reproductive success of the two male phenotypes would vary with their relative frequency in the population. Adult Chinook salmon males nearly always obtained primary access to nesting females and were first to enter the nest at the time of spawning. Jack male spawning occurred primarily by establishing satellite positions downstream of the courting pair, and 'sneaking' into the nest at the time of spawning. Male dominance hierarchies were fairly stable and strongly correlated with the order of nest entry at the time of spawning. Observed participation in spawning events and adult-to-fry reproductive success of jack and adult males was consistent with a negative frequency-dependent selection model. Overall, jack males sired an average of 21% of the offspring produced across a range of jack male frequencies. Implications of these and additional findings on Chinook salmon hatchery broodstock management will be presented in the FY 2009 Annual Report. Objective 2: To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon were exposed to known odorants at key developmental stages. Molecular assessments of imprinting-induced changes in odorant receptor gene expression indicated that regulation of odorant expression is influenced by developmental status and odor exposure history. Expression levels of basic amino acid receptor (BAAR) mRNA in the olfactory

  14. Genetic management of broodstock populations with DNA markers in rainbow trout

    Science.gov (United States)

    DNA markers are very useful for aquaculture and fisheries broodstock management. They have been used for parentage assignment when spawning families share common environments, and to evaluate genetic parameters in broodstock populations. The selective breeding program at the National Center for Cool...

  15. Redfish Lake Sockeye Salmon Captive Broodstock Rearing and Research, 2001 : Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Frost, Deborah A.; McAuley, W. Carlin; Maynard, Desmond J.

    2002-04-01

    The National Marine Fisheries Service (NMFS) Northwest Fisheries Science Center, in cooperation with the Idaho Department of Fish and Game and the Bonneville Power Administration, has established captive broodstock and captive rearing programs to aid recovery of Snake River sockeye salmon (Oncorhynchus nerka) listed as endangered under the U.S. Endangered Species Act (ESA). Captive broodstock and captive rearing programs are a form of artificial propagation that are emerging as an important component of restoration efforts for ESA-listed salmon populations that are at critically low numbers. Captive broodstocks, reared in captivity for the entire life cycle, couple the salmon's high fecundity with potentially high survival in protective culture to produce large numbers of juveniles in a single generation for supplementation of natural populations. The captive broodstocks discussed in this report were intended to protect the last known remnants of sockeye salmon that return to Redfish Lake in the Sawtooth Basin of Idaho at the headwaters of the Salmon River. This report addresses NMFS research from 1 September 2000 to 31 August 2001 on the Redfish Lake sockeye salmon captive broodstock and captive rearing program. NMFS currently has broodstock in culture from year classes 1997, 1998, 1999, and 2000 in both the captive broodstock and captive rearing programs. Offspring from these programs are being returned to Idaho to aid recovery efforts for the species.

  16. Redfish Lake sockeye salmon captive broodstock rearing and research, 1994. Annual report

    International Nuclear Information System (INIS)

    The National Marine Fisheries Service (NMFS) Northwest Fisheries Science Center, in cooperation with the Idaho Department of Fish and Game (IDFG) and the Bonneville Power Administration, has established captive broodstocks to aid recovery of Snake River sockeye salmon (Oncorhynchus nerka) listed as endangered under the US Endangered Species Act (ESA). Captive broodstock programs are emerging as an important component of restoration efforts for ESA-listed salmon populations. Captive broodstock programs are a form of artificial propagation. However, they differ from standard hatchery techniques in one important respect: fish are cultured in captivity for the entire life cycle. The high fecundity of Pacific salmon, coupled with their potentially high survival in protective culture, affords an opportunity for captive broodstocks to produce large numbers of juveniles in a single generation for supplementation of natural populations. The captive broodstocks discussed in this report were intended to protect the last known remnants of this stock: sockeye salmon that return to Redfish Lake in the Sawtooth Basin of Idaho at the headwaters of the Salmon River. This report addresses NMFS research from January to December 1994 on the Redfish Lake sockeye salmon captive broodstock program and summarizes results since the beginning of the study in 1991. Spawn from NMFS Redfish Lake sockeye salmon captive broodstocks is being returned to Idaho to aid recovery efforts for the species

  17. Redfish Lake Sockeye Salmon Captive Broodstock Rearing and Research, 1994 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Flagg, Thomas A.

    1996-03-01

    The National Marine Fisheries Service (NMFS) Northwest Fisheries Science Center, in cooperation with the Idaho Department of Fish and Game (IDFG) and the Bonneville Power Administration, has established captive broodstocks to aid recovery of Snake River sockeye salmon (Oncorhynchus nerka) listed as endangered under the US Endangered Species Act (ESA). Captive broodstock programs are emerging as an important component of restoration efforts for ESA-listed salmon populations. Captive broodstock programs are a form of artificial propagation. However, they differ from standard hatchery techniques in one important respect: fish are cultured in captivity for the entire life cycle. The high fecundity of Pacific salmon, coupled with their potentially high survival in protective culture, affords an opportunity for captive broodstocks to produce large numbers of juveniles in a single generation for supplementation of natural populations. The captive broodstocks discussed in this report were intended to protect the last known remnants of this stock: sockeye salmon that return to Redfish Lake in the Sawtooth Basin of Idaho at the headwaters of the Salmon River. This report addresses NMFS research from January to December 1994 on the Redfish Lake sockeye salmon captive broodstock program and summarizes results since the beginning of the study in 1991. Spawn from NMFS Redfish Lake sockeye salmon captive broodstocks is being returned to Idaho to aid recovery efforts for the species.

  18. Redfish Lake Sockeye Salmon Captive Broodstock Rearing and Research, Annual Report 2001-2002.

    Energy Technology Data Exchange (ETDEWEB)

    Frost, Deborah; McAuley, W.; Maynard, Desmond

    2003-04-01

    The National Marine Fisheries Service (NMFS) Northwest Fisheries Science Center, in cooperation with the Idaho Department of Fish and Game and the Bonneville Power Administration, has established captive broodstock programs to aid recovery of Snake River sockeye salmon (Oncorhynchus nerka) listed as endangered under the U.S. Endangered Species Act (ESA). Captive broodstock and captive rearing programs are a form of artificial propagation that are emerging as an important component of restoration efforts for ESA-listed salmon populations that are at critically low numbers. Captive broodstocks, reared in captivity for the entire life cycle, couple the salmon's high fecundity with potentially high survival in protective culture to produce large numbers of juveniles in a single generation for supplementation of natural populations. The captive broodstocks discussed in this report were intended to protect the last known remnants of sockeye salmon that return to Redfish Lake in the Sawtooth Basin of Idaho at the headwaters of the Salmon River. This report addresses NMFS activities from 1 September 2001 to 31 August 2002 on the Redfish Lake sockeye salmon captive broodstock and captive rearing program. NMFS currently has broodstocks in culture from year classes 1997, 1998, 1999, 2000, and 2001 in both the captive breeding and captive rearing programs. Offspring from these programs are being returned to Idaho to aid recovery efforts for the species.

  19. Redfish Lake Sockeye Salmon Captive Broodstock Rearing and Research, 1995-2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Flagg, Thomas A.

    2001-01-01

    The National Marine Fisheries Service (NMFS) Northwest Fisheries Science Center, in cooperation with the Idaho Department of Fish and Game and the Bonneville Power Administration, has established captive broodstocks to aid recovery of Snake River sockeye salmon (Oncorhynchus nerka) listed as endangered under the US Endangered Species Act (ESA). Captive broodstock programs are a form of artificial propagation and are emerging as an important component of restoration efforts for ESA-listed salmon populations. However, they differ from standard hatchery techniques in one important respect: fish are cultured in captivity for the entire life cycle. The high fecundity of Pacific salmon, coupled with their potentially high survival in protective culture, affords an opportunity for captive broodstocks to produce large numbers of juveniles in a single generation for supplementation of natural populations. The captive broodstocks discussed in this report were intended to protect the last known remnants of this stock: sockeye salmon that return to Redfish Lake in the Sawtooth Basin of Idaho at the headwaters of the Salmon River. This report addresses NMFS research from January 1995 to August 2000 on the Redfish Lake sockeye salmon captive broodstock program and summarizes results since the beginning of the study in 1991. Since initiating captive brood culture in 1991, NMFS has returned 742,000 eyed eggs, 181 pre-spawning adults, and over 90,000 smolts to Idaho for recovery efforts. The first adult returns to the Stanley Basin from the captive brood program began with 7 in 1999, and increased to about 250 in 2000. NMFS currently has broodstock in culture from year classes 1996, 1997, 1998, and 1999 in both the captive broodstock program, and an adult release program. Spawn from NMFS Redfish Lake sockeye salmon captive broodstocks is being returned to Idaho to aid recovery efforts for the species.

  20. Manchester Spring Chinook Broodstock Project : Progress Report, 2000.

    Energy Technology Data Exchange (ETDEWEB)

    McAuley, W. Carlin; Wastel, Michael R.; Flagg, Thomas A. (Thomas Alvin)

    2000-11-01

    In spring 1995 the Idaho Department of Fish and Game (IDFG) and the Oregon Department of Fish and Wildlife (ODFW) initiated captive broodstocks as part of conservation efforts for ESA-listed stocks of Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha). The need for this captive broodstock strategy was identified as critical in the National Marine Fisheries Service (NMFS) Proposed Recovery Plan for Snake River Salmon. These captive broodstock programs are being coordinated by the Bonneville Power Administration (BPA) through the Chinook Salmon Captive Propagation Technical Oversight Committee (CSCPTOC). Oregon's Snake River spring/summer chinook salmon captive broodstock program currently focuses on three stocks captured as juveniles from the Grande Ronde River Basin: the upper Grande Ronde River, Catherine Creek, and the Lostine River. Idaho's Snake River program includes three stocks captured as eggs and juveniles from the Salmon River Basin: the Lemhi River, East Fork Salmon River, and West Fork Yankee Fork. The majority of captive fish from each stock of the Grande Ronde Basin will be grown to maturity in freshwater at the ODFW Bonneville Hatchery. A minority of the Salmon River Basin stocks will be grown to maturity in freshwater at the IDFG Eagle Hatchery. However, the IDFG and ODFW requested that a portion of each group also be reared in protective culture in seawater. In August 1996, NMFS began a BPA funded project (Project 96-067-00) to rear Snake River spring/summer chinook salmon captive broodstocks in seawater at the NMFS Manchester Research Station. During 1997-1999, facilities modifications were undertaken at Manchester to provide secure facilities for rearing of these ESA-listed fish. This included construction of a building housing a total of twenty 6.1-m diameter fiberglass rearing tanks, upgrade of the Manchester salt water pumping and filtration/sterilization systems to a total capacity of 5,670 L/min (1,500 gpm), and

  1. Research on Captive Broodstock Technology for Pacific Salmon, 1995 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Swanson, Penny; Pascho, Ronald; Hershberger, William K. (Northwest and Alaska Fisheries Center, Coastal Zone and Estuarine Studies Division, Seattle, WA)

    1996-01-01

    This report summarizes research on captive broodstock technologies conducted during 1995 under Bonneville Power Administration Project 93-56. Investigations were conducted by the National Marine Fisheries Service (NMFS) in cooperation with the US Fish and Wildlife Service, University of Washington, and Northwest Biological Science Center (US Geological Survey). Studies encompassed several categories of research, including fish husbandry, reproductive physiology, immunology, pathology, nutrition, and genetics. Captive broodstock programs are being developed and implemented to aid recovery of endangered Pacific salmon stocks. Like salmon hatchery programs, however, captive broodstock programs are not without problems and risks to natural salmon populations. The research projects described in this report were developed in part based on a literature review, Assessment of the Status of Captive Broodstock Technology for Pacific Salmon. The work was divided into three major research areas: (1) research on sockeye salmon; (2) research on spring chinook salmon; and (3) research on quantitative genetic problems associated with captive broodstock programs. Investigations of nutrition, reproductive physiology, fish husbandry, and fish health were integrated into the research on sockeye and spring chinook salmon. A description of each investigation and its major findings and conclusions is presented.

  2. An Assessment of the Status of Captive Broodstock Technology of Pacific Salmon, 1995 Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Flagg, Thomas A.; Mahnaken, Conrad V.W.; Hard, Jeffrey J.

    1995-06-01

    This report provides guidance for the refinement and use of captive broodstock technology for Pacific salmon (Oncorhynchus spp.) by bringing together information on the husbandry techniques, genetic risks, physiology, nutrition, and pathology affecting captive broodstocks. Captive broodstock rearing of Pacific salmon is an evolving technology, as yet without well defined standards. At present, we regard captive rearing of Pacific salmon as problematic: high mortality rates and low egg viability were common in the programs we reviewed for this report. One of the most important elements in fish husbandry is the culture environment itself. Many captive broodstock programs for Pacific salmon have reared fish from smolt-to-adult in seawater net-pens, and most have shown success in providing gametes for recovery efforts. However, some programs have lost entire brood years to diseases that transmitted rapidly in this medium. Current programs for endangered species of Pacific salmon rear most fish full-term to maturity in fresh well-water, since ground water is low in pathogens and thus helps ensure survival to adulthood. Our review suggested that captive rearing of fish in either freshwater, well-water, or filtered and sterilized seawater supplied to land-based tanks should produce higher survival than culture in seawater net-pens.

  3. Quality of Blue swimming crab Portunus pelagicus Larvae from Domesticated Broodstock

    OpenAIRE

    Trijuno, Dody; Fujaya, Yushinta; Agviranti; Marhama, Syamsurya

    2015-01-01

    Blue swimming crab (Portunus pelagicus) is the important world fishery resource, but the crab larval rearing faces high mortality problem. The aim of the research was to compare survival and growth rate of larvae resulted from wild and domesticated broodstock blue swimming crab. Domesticated and wild broodstock were used to produce larvae. Domesticated broodstock was selected from repeated reared crab until third generation. Selection of the broodstock mainly based on the survival and gro...

  4. Fault Localization for Java Programs using Probabilistic Program Dependence Graph

    CERN Document Server

    Askarunisa, A; Babu, B Giri

    2012-01-01

    Fault localization is a process to find the location of faults. It determines the root cause of the failure. It identifies the causes of abnormal behaviour of a faulty program. It identifies exactly where the bugs are. Existing fault localization techniques are Slice based technique, Program- Spectrum based Technique, Statistics Based Technique, Program State Based Technique, Machine learning based Technique and Similarity Based Technique. In the proposed method Model Based Fault Localization Technique is used, which is called Probabilistic Program Dependence Graph . Probabilistic Program Dependence Graph (PPDG) is an innovative model that scans the internal behaviour of the project. PPDG construction is enhanced by Program Dependence Graph (PDG). PDG is achieved by the Control Flow Graph (CFG). The PPDG construction augments the structural dependences represented by a program dependence graph with estimates of statistical dependences between node states, which are computed from the test set. The PPDG is base...

  5. Nutrient effects of broodstocks on the larvae in Patinopecten yessoensis

    Science.gov (United States)

    Bai, Yucen; Zhang, Tao; Qiu, Tianlong; Gao, Yan; Zhang, Xiaofang

    2015-07-01

    Patinopecten yessoensis is a commercial valuable species. This study deals with the effect of nutrient effects of the broodstock (mainly ovaries) on the larvae. Concentrations of total carbohydrate, total protein and total lipid in the gonads of P. yessoensis from three Hatcheries (Hatchery 1, Hatchery 2, and Hatchery 3) were determined before and after spawning. The relationship between the nutrient concentration in ovaries before spawning (BC) and that of larvae (LC) was assessed as well as the change in nutrient levels in ovaries after spawning (DC). Results indicate that the BC of total carbohydrate (7.66%) and total lipid (14.48%) in ovaries were significantly higher than in testes (5.20%, 5.20% respectively), whereas the BC of total protein in the ovaries was lower (61.76%) than in the testes (81.67%). The different gonadal composition suggests the different nutrient demands between male and female broodstocks in breeding season. Patinopecten yessoensis gonads contained a higher proportion of lipids, in comparison to other bivalves, which might be a response to the low ambient water temperatures. Further analysis of fatty acids showed that the concentrations of n-3PUFA, EPA and DHA in larvae (LC) were positively correlated with BC and DC, indicating the significant nutrient influence of broodstocks on the larvae. As these fatty acids are important in metabolism, and have been demonstrated to be influential to the viability of the larvae, larval growth and the settlement, spat growth, and juvenile survival in many bivalves, they could possibly be used as indexes to evaluate, and predict condition of broodstocks and larvae.

  6. Analysis of turbot (Scophthalmus maximus) broodstock pilot scale production.

    OpenAIRE

    Omnes, Marie-helene; Normant, Yvon; Suquet, Marc; FAUVEL, Christian

    1991-01-01

    Rearing turbot (Scophthalmus maximus) reaches the commercial scale. With the hatchery output increasing, more attention needs to be focussed on broodstocks performance both in terms of quantity and viability of eggs. The techniques of shifting the environmental conditions allow a production of eggs all year round. However, egg quality tends to be highly variable. This paper examines over a two-year period, the improvement in egg quality and its consequences on the production of larvae by a st...

  7. Fault Localization for Java Programs Using Probabilistic Program Dependence Graph

    Directory of Open Access Journals (Sweden)

    A. Askarunisa

    2011-11-01

    Full Text Available Fault localization is a process to find the location of faults. It determines the root cause of the failure. It identifies the causes of abnormal behaviour of a faulty program. It identifies exactly where the bugs are. Existing fault localization techniques are Slice based technique, Program- Spectrum based Technique, Statistics Based Technique, Program State Based Technique, Machine learning based Technique and Similarity Based Technique. In the proposed method Model Based Fault Localization Technique is used, which is called Probabilistic Program Dependence Graph . Probabilistic Program Dependence Graph (PPDG is an innovative model that scans the internal behaviour of the project. PPDG construction is enhanced by Program Dependence Graph (PDG. PDG is achieved by the Control Flow Graph (CFG. The PPDG construction augments the structural dependences represented by a program dependence graph with estimates of statistical dependences between node states, which are computed from the test set. The PPDG is based on the established framework of probabilistic graphical models. This work presents algorithms for constructing PPDGs and applying fault localization.

  8. Instancewise Array Dependence Test for Recursive Programs

    OpenAIRE

    Amiranoff, Pierre; Cohen, Albert; Feautrier, Paul

    2003-01-01

    Starting from a generalization of induction variables,we present a dependence test framework for recursive programs. For a restricted class of programs, a statically computable function maps every run-time instance of a programstatement to the data-structure elements it accesses. Statement instances and data structure layouts are describedthrough formal language tools.This framework is applied to the automatic detection ofdata and control parallelism. We extend the concept of instancewise dat...

  9. Flavobacterium psychrophilum Infections in Salmonid Broodstock and Hatchery-Propagated Stocks of the Great Lakes Basin.

    Science.gov (United States)

    Van Vliet, Danielle; Loch, Thomas P; Faisal, Mohamed

    2015-12-01

    Bacterial coldwater disease (BCWD), caused by Flavobacterium psychrophilum, threatens wild and propagated salmonids worldwide and leads to substantial economic losses. In addition to being horizontally transmitted, F. psychrophilum can be passed from infected parents to their progeny, furthering the negative impacts of this pathogen. In Michigan, both feral and captive salmonid broodstocks are the gamete sources used in fishery propagation efforts. A 5-year study was initiated to follow the prevalence of systemic F. psychrophilum infections in feral broodstocks of four species (steelhead Oncorhynchus mykiss [potadromous Rainbow Trout]; Coho Salmon O. kisutch; Chinook Salmon O. tshawytscha; and Atlantic Salmon Salmo salar) residing in three Great Lakes watersheds. Additionally, captive broodstocks of four species (Rainbow Trout, Brown Trout Salmo trutta, Lake Trout Salvelinus namaycush, and Brook Trout Salvelinus fontinalis) maintained at two facilities were assessed for the presence of F. psychrophilum. The resultant offspring from each broodstock population were sampled for F. psychrophilum infections multiple times throughout hatchery residency. Using selective flavobacterial culture and PCR confirmation, F. psychrophilum was detected in all broodstocks except the captive Lake Trout and Brook Trout. Logistic regression analysis demonstrated that among the infected feral broodstocks, Chinook Salmon from the Lake Michigan watershed had the highest prevalence of systemic F. psychrophilum infection (mean = 63.2%). Among the captive broodstocks, the Gilchrist Creek strain of Brown Trout had the highest infection prevalence (mean = 5%). Collectively, the captive broodstocks were found to have significantly lower infection prevalence than the feral broodstocks. Despite the high prevalence of systemic F. psychrophilum infections in many broodstock populations, the bacterium was rarely detected in their progeny during hatchery rearing. However, heavy losses associated

  10. Profile sampling dependence of the MLAYER program.

    OpenAIRE

    Chang, Ting-Hsun

    1991-01-01

    Approved for public release; distribution is unlimited The dependence of the predictions of the MLAYER program on the set of heights at which the refractive index value are sampled from a fixed reference profile are analyzed. A refractivity profile with a four-meter evaporation duct is adopted as a reference. Two variable piecewise linear profiles of four and five segments, respectively, are used to approximate the reference profile for MLAYER computations. The sensitivities...

  11. Effects of immobilization by electricity and MS-222 on brown trout broodstock and their progeny

    Science.gov (United States)

    Redman, S.D.; Meinertz, J.R.; Gaikowski, M.P.

    1998-01-01

    To determine the effects of electrically and chemically induced immobilization on postspawn broodstock and their progeny, age-2 and age-3 female broodstock and age-2 male broodstock of brown trout Salmo trutta were immobilized with electricity or tricaine methanesulfonate (MS-222), stripped of their eggs or milt, and weighed. Eggs taken from electrically immobilized females were fertilized with milt taken from age-2 males that were immobilized with electricity, and eggs taken from females immobilized with MS-222 were fertilized with milt taken from age-2 males that were immobilized with MS-222. After spawning, the mortality and weight of broodstock were compared twice over a 6-month period. Egg viability and growth of offspring fry from each treatment group were also compared. Electricity induced complete and consistent immobilization in brown trout broodstock. Electrically immobilized fish were more easily handled than fish immobilized with MS-222; however, electrically immobilized fish survival (70%) was significantly less than fish immobilized with MS-222 (83%). Broodstock growth differences were only noted at 6 months postexposure, when the mean weight of electrically immobilized fish was slightly less than the weight of fish immobilized with MS-222. Broodstock immobilization by electricity did not reduce egg viability or fry growth.

  12. Profile sampling dependence of the MLAYER program

    Science.gov (United States)

    Chang, Ting-Hsun

    1991-03-01

    The dependence of the predictions of the MLAYER program on the set of heights at which the refractive index value are sampled from a fixed reference profile are analyzed. A refractivity profile with a four-meter evaporation duct is adopted as a reference. Two variable piecewise linear profiles of four and five segments, respectively, are used to approximate the reference profile for MLAYER computations. The sensitivities of the waveguide mode location, the range attenuation rate, and the height-gain function to the changes of the piece-wise linear profiles are investigated at the frequencies 3, 6, 10, and 15 GHz. The frequency dependence of the dominant mode for one profile is also studied to investigate the fact that the sensitivity to changes in sampling point location is lower at GHz than at other frequencies. A general rule-of-thumb for the change in range attenuation rate due to a slight change in refractivity is suggested.

  13. Tench broodstock management in breeding station under conditions of pond culture: a review

    Czech Academy of Sciences Publication Activity Database

    Gela, David; Flajšhans, Martin; Kocour, Martin; Rodina, Marek; Linhart, Otomar

    2006-01-01

    Roč. 14, 2 (2006), s. 195-203. ISSN 0967-6120 Institutional research plan: CEZ:AV0Z50450515 Keywords : broodstock * farming cycle * fish identification Subject RIV: GL - Fishing Impact factor: 0.943, year: 2006

  14. Genetic characterization of broodstock brown trout from Bled fish-farm, Slovenia

    OpenAIRE

    Marić, Saša; Simonović, Predrag; Razpet, Andrej

    2010-01-01

    Background and Purpose: Due to environmental and economic concerns, Bled fish-farm is interested in establishing broodstocks of native brown trout (Salmo trutta L.). Progeny would be reared and released into rivers managed by the Fishing Club Bled. In this study was performed genetic characterization of broodstock from Bled fish-farm in order to assess hybridization of native brown trout of Danubian phylogeographic lineage with trout of the allochtonous Atlantic lineage. Material and Meth...

  15. Snake River Spring/Summer Chinook Captive Broodstock Rearing and Research, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McAuley, W. Carlin; Flagg, Thomas N. (National Marine Fisheries Service, Northwest Fisheries Science Center, Seattle, WA)

    2003-03-01

    In 1995, the National Marine Fisheries Service (NMFS), in cooperation with the Idaho Department of Fish and Game (IDFG), the Oregon Department of Fish and Wildlife (ODFW), and the Bonneville Power Administration (BPA) established captive broodstock programs to aid in the recovery of Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha) listed as endangered under the U.S. Endangered Species Act (ESA). These programs were intended to provide safety nets for Salmon and Grande Ronde River Basins spring/summer chinook salmon stocks. They also provide a basis of examining the efficacy of captive rearing and captive breeding programs as tools for recovering listed salmonid populations. In years when no or few naturally produced fish return from the sea, captive fish and their progeny can be used to maintain populations in these two Snake River Basin tributaries. The NMFS facility at Manchester, WA, provides the crucial seawater environment needed to culture anadromous salmonids during the marine phase of their life cycle. At the Manchester Research Station, the fish are cultured in 6.1m diameter circular tanks housed in a fully enclosed and secure building. The tanks are supplied with seawater that has been processed to eliminate most marine pathogens. The fish are fed a commercially prepared diet and held at densities and loading rates designed to maximize fish quality. When fish begin to mature, they are transferred to ODFW or IDFG freshwater facilities in Oregon and Idaho for final maturation. The states then release the mature fish (Idaho) or their progeny (Oregon) back into their native Snake River tributary waters in restoration efforts. In FY 2001, NMFS cultured 1996, 1997, 1998, and 1999 broodyear fish at its Manchester Facility. This report addresses program activities from September 1, 2000 to August 31, 2001.

  16. Snake River Spring/Summer Chinook Captive Broodstock Rearing and Research, 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McAuley, W. Carlin; Maynard, Desmond J. (National Marine Fishereis Service, Northwest Fisheries Science Center, Seattle, WA)

    2003-03-01

    In 1995, the National Marine Fisheries Service (NMFS), in cooperation with the Idaho Department of Fish and Game (IDFG), the Oregon Department of Fish and Wildlife (ODFW), and the Bonneville Power Administration (BPA) established captive broodstock programs to aid in the recovery of Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha) listed as endangered under the U.S. Endangered Species Act (ESA). These programs were intended to provide safety nets for Salmon and Grande Ronde River Basins spring/summer chinook salmon stocks. They also provide a basis of examining the efficacy of captive rearing and captive breeding programs as tools for recovering listed salmonid populations. In years when no or few naturally produced fish return from the sea, captive fish and their progeny can be used to maintain populations in these two Snake River Basin tributaries. The NMFS facility at Manchester, WA, provides the crucial seawater environment needed to culture anadromous salmonids during the marine phase of their life cycle. At the Manchester Research Station, the fish are cultured in 6.1m diameter circular tanks housed in a fully enclosed and secure building. The tanks are supplied with seawater that has been processed to eliminate most marine pathogens. The fish are fed a commercially prepared diet and held at densities and loading rates designed to maximize fish quality. When fish begin to mature, they are transferred to ODFW or IDFG freshwater facilities in Oregon and Idaho for final maturation. The states then release the mature fish (Idaho) or their progeny (Oregon) back into their native Snake River tributary waters in restoration efforts. In FY 2002, NMFS cultured 1996, 1997, 1998, 1999, and 2000 broodyear fish at its Manchester Facility. This report addresses program activities from September 1, 2001 to August 31, 2002.

  17. Snake River Spring/Summer Chinook Captive Broodstock Rearing and Research, 2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Maynard, Desmond J.; McAuley, W. Carlin (National Marine Fisheries Service, Northwest Fisheries Science Center, Resource Enhancement and Utilization, Seattle, WA)

    2004-08-01

    In 1995, the National Marine Fisheries Service (NMFS), in cooperation with the Idaho Department of Fish and Game (IDFG), the Oregon Department of Fish and Wildlife (ODFW), and the Bonneville Power Administration (BPA) established captive broodstock programs to aid in the recovery of Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha) listed as endangered under the U.S. Endangered Species Act (ESA). These programs are intended to provide safety nets for Salmon and Grande Ronde River Basins spring/summer chinook salmon stocks. They also provide a basis of examining the efficacy of captive rearing and captive breeding programs as tools for recovering listed salmonid populations. In years when no or few naturally produced fish return from the sea, captive fish and their progeny can be used to maintain populations in these two Snake River Basin tributaries. The NMFS facility at Manchester, WA provides the crucial seawater environment needed to culture anadromous salmonids during the marine phase of their life cycle. At the Manchester Research Station, the fish are cultured in 6.1m diameter circular tanks housed in a fully enclosed and secure building. The tanks are supplied with seawater that has been processed to eliminate most marine pathogens. The fish are fed a commercially prepared diet and held at densities and loading rates intended to maximize fish quality. When fish begin to mature, they are transferred to ODFW or IDFG freshwater facilities in Oregon and Idaho for final maturation. The states then release the mature fish (Idaho) or their progeny (Oregon) back into their native Snake River tributary waters in restoration efforts. In FY 2003, NMFS cultured 1998, 1999, 2000, and 2001 broodyear fish at its Manchester Facility. This report addresses program activities from September 1, 2002 to August 31, 2003.

  18. Redfish Lake Sockeye Salmon Captive Broodstock Rearing and Research, 1993 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Flagg, Thomas A.

    1994-11-01

    The National Marine Fisheries Service (NMFS), in cooperation with Idaho and BPA, has established captive broodstocks to aid recovery of endangered Snake River sockeye salmon. NMFS is currently maintaining four separate Redfish Lake sockeye Salmon captive broodstocks; all these broodstocks are being reared full-term to maturity in fresh (well) water. Experiments are also being conducted on nonendangered 1990 and 1991-brood Lake Wenatchee (WA) sockeye salmon to compare effects on survival and reproduction to maturity in fresh water and seawater; for both brood-years, fish reared in fresh water were larger than those reared in seawater. Data from captive rearing experiments suggest a ranking priority of circular tanks supplied with pathogen-free fresh water, circular tanks supplied with pumped/filtered/uv-sterilized seawater, and seawater net-pens for rearing sockeye salmon to maturity.

  19. Exploring and Enforcing Application Security Guarantees vis Program Dependence

    OpenAIRE

    Johnson, Andrew; Waye, Lucas Reed; Moore, Scott David; Chong, Stephen N

    2014-01-01

    We present Pidgin, a program analysis and understanding tool that allows developers to explore the information flows that exist in programs and specify and enforce security policies that restrict these information flows. Pidgin uses program-dependence graphs (PDGs) to precisely capture the information flows within a program. PDGs can be queried using a custom query language to explore and describe information flows in programs. A developer can specify strong information security policies by a...

  20. Do students' programming skills depend on programming language?

    Science.gov (United States)

    Savić, Miloš; Ivanović, Mirjana; Budimac, Zoran; Radovanović, Miloš

    2016-06-01

    Bachelor studies in Computer Science at our department in the last decades cover several successive core courses in programming: Introduction to Programming, Data Structures and Algorithms 1 and 2, Operating Systems and Compiler Construction. For a long time our intention was not to insist on the realization of subjects in a specific programming language, but to put emphasis on abstract reasoning and appropriate data structures and algorithms. Also, to avoid teaching different languages and programming environments, we decided to use one good educational language - Modula-2. In the last several years we were under different kinds of pressure to change the language. Starting from the last school-year we decided to adopt Java within the introductory programming course, using the imperative approach first. Some comparisons of students' advancements and success between Modula-2 and Java generations are presented in the paper. The results of the analytical evaluation indicate that the choice of the first programming language does not have a deep influence to students' success at the course.

  1. Diversidade genética de estoques de reprodutores de Colossoma macropomum Genetic diversity of Colossoma macropomum broodstocks

    Directory of Open Access Journals (Sweden)

    T.S. Lopes

    2009-06-01

    Full Text Available Analisou-se a diversidade genética de estoques de reprodutores de Tambaqui (Colossoma macropomum, mediante o uso de marcador RAPD, utilizando-se 10 primers para analisar 30 amostras do estoques de reprodutores das pisciculturas de Boa Esperança e Vale Verde, localizadas no Estado de Rondônia. A porcentagem de fragmentos polimórficos e o índice de diversidade genética de Shannon foram altos nos dois estoques de reprodutores. O estoque de reprodutores de Boa Esperança apresentou um fragmento exclusivo. A diferenciação genética foi baixa e o número de migrantes por geração foi alto entre os estoques de reprodutores. O dendrograma não separou os indivíduos dos estoques de reprodutores em grupos distintos. Há alta variabilidade genética nos estoques de reprodutores, um pouco inferior no estoque de Vale Verde, e há grande proximidade genética entre os indivíduos dos estoques de reprodutores.The genetic diversity of tambaqui (Colossoma macropomum broodstocks from two hatchery station in Rondônia State was studied by the RAPD marker. Ten primers were used to analyze 30 broodstocks samples from the hatchery stations of Boa Esperança and Vale Verde. The polymorphic fragments percentage and Shannon genetic diversity index were high in the two broodstocks. The Boa Esperança broodstock presented an exclusive fragment. The genetic differentiation was low and the number of migrants per generation was high among the broodstocks. The dendrogram did not separate the broodstocks individuals in different groups. The results indicate a high genetic variability in the broodstocks, being a little bit lower in the Vale Verde broodstock. Besides, there is a genetic proximity among the broodstocks.

  2. Characterizing the Genetic Diversity of Rainbow Trout in Support of Broodstock Development

    Science.gov (United States)

    The use of molecular genetic technologies for broodstock management and selective breeding of aquaculture species is becoming increasingly more common with the continued development of species-specific genome tools and reagents. Rainbow trout are the most widely produced salmonid in the US, attract...

  3. Development of Genetically-defined Yellow Perch (Perca flavescens) Broodstocks for Selective Breeding

    Science.gov (United States)

    We have initiated development of genetically defined yellow perch (Perca flavescens) broodstocks. For this, sixteen wild perch populations throughout the U.S. were sampled and analyzed using published (Leclerc et al. Molecular Ecology 2000, 9: 993-1011) and newly developed microsatellite loci. Gen...

  4. Streptococcal Arthritis, Osteolysis, Myositis, and Spinal Meningitis in Channel Catfish Ictalurus punctatus Broodstock

    Science.gov (United States)

    This report details findings of an investigation into complaints by commercial fingerling producers of low-grade mortalities, poor reproductive success, emaciation, skin lesions, and severely arched backs among broodstock of channel catfish Ictalurus punctatus. Gross lesions involved the jaw, fin ba...

  5. RECRUITMENT OF GROUPER BROODSTOCK ON THE BASIS OF SINGLE LOCUS DNA MARKERS

    OpenAIRE

    Rodrigues Kenneth Francis; Zaidi Ahmad Tani; Syarul Nataqain Baharum

    2016-01-01

    The manuscript describes the development and application of molecular markers for the selection of broodstock of two species of Groupers Epinephelus fuscoguttatus and E. corallicola using single locus DNA markers. The article presents a database of verified DNA markers which can be applied for fish breeding and genetic selection.

  6. Genetic assessment tools for evaluating broodstock population structure and pedigree reconstruction in rainbow trout

    Science.gov (United States)

    DNA markers are very useful for aquaculture and fisheries broodstock management, but the cost of these technologies remains prohibitive for some applications. DNA markers have been used for parentage assignment when families share a common environment, and for evaluating population structure and oth...

  7. Broodstock management and hormonal manipulations of fish reproduction.

    Science.gov (United States)

    Mylonas, Constantinos C; Fostier, Alexis; Zanuy, Silvia

    2010-02-01

    Control of reproductive function in captivity is essential for the sustainability of commercial aquaculture production, and in many fishes it can be achieved by manipulating photoperiod, water temperature or spawning substrate. The fish reproductive cycle is separated in the growth (gametogenesis) and maturation phase (oocyte maturation and spermiation), both controlled by the reproductive hormones of the brain, pituitary and gonad. Although the growth phase of reproductive development is concluded in captivity in most fishes-the major exemption being the freshwater eel (Anguilla spp.), oocyte maturation (OM) and ovulation in females, and spermiation in males may require exogenous hormonal therapies. In some fishes, these hormonal manipulations are used only as a management tool to enhance the efficiency of egg production and facilitate hatchery operations, but in others exogenous hormones are the only way to produce fertilized eggs reliably. Hormonal manipulations of reproductive function in cultured fishes have focused on the use of either exogenous luteinizing hormone (LH) preparations that act directly at the level of the gonad, or synthetic agonists of gonadotropin-releasing hormone (GnRHa) that act at the level of the pituitary to induce release of the endogenous LH stores, which, in turn act at the level of the gonad to induce steroidogenesis and the process of OM and spermiation. After hormonal induction of maturation, broodstock should spawn spontaneously in their rearing enclosures, however, the natural breeding behavior followed by spontaneous spawning may be lost in aquaculture conditions. Therefore, for many species it is also necessary to employ artificial gamete collection and fertilization. Finally, a common question in regards to hormonal therapies is their effect on gamete quality, compared to naturally maturing or spawning broodfish. The main factors that may have significant consequences on gamete quality-mainly on eggs-and should be considered

  8. DEPENDENCE FLOW GRAPH FOR ANALYSIS OF ASPECT- ORIENTED PROGRAMS

    Directory of Open Access Journals (Sweden)

    Syarbaini Ahmad

    2014-12-01

    Full Text Available Program analysis is useful for debugging, testing and maintenance of software systems due to information about the structure and relationship of the program’s modules . In general, program analysis is performed either based on control flow graph or dependence graph. However, in the case of aspect-oriented programming (AOP, control flow graph (CFG or dependence graph (DG are not enough to model the properties of Aspect-oriented (AO programs. With respect to AO programs, although AOP is good for modular representation and crosscutting concern, suitable model for program analysis is required to gather information on its structure for the purpose of minimizing maintenance effort. In this paper Aspect Oriented Dependence Flow Graph (AODFG as an intermediate representation model is proposed to represent the structure of aspect-oriented programs. AODFG is formed by merging the CFG and DG, thus more information about dependencies between the join points, advice, aspects and their associated construct with the flow of control from one statement to another are gathered. We discussthe performance of AODFG by analysing some examples of AspectJ program taken from AspectJ Development Tools (AJDT.

  9. Biofloc technology applied to rear shrimp Litopenaeus Stylirostris broodstock: An integrated and development research project in New Caledonia and French Polynesia

    OpenAIRE

    Chim, Liet; Cardona, Emilie; Lorgeoux, Benedicte; Gueguen, Yannick; Saulnier, Denis; Goguenheim, Jean; Wantiez, Laurent; Cahu, Chantal

    2014-01-01

    Shrimp farming in New-Caledonia faces up to difficulties. A fluctuating quality of broodstock prevents sustainable production of larvae in quantity and quality. The traditional extensive rearing method of broodstock in outdoor earthen ponds used in New Caledonia raises several issues: poor water quality control and biosecurity. Therefore it is fundamental to modify the broodstock culture strategy in order to achieve an easier water quality management and maximal biosecurity. Biofloc technolog...

  10. Conditioning of broodstock of tiger grouper, Epinephelus fuscoguttatus, in a recirculating aquaculture system

    OpenAIRE

    Saleem Mustafa; Mohd. Hafizzie Hajini; Shigeharu Senoo; Annita Yong Seok Kian

    2015-01-01

    Closing the cycle of commercial species of fish in a recirculating aquaculture system is gaining importance for a number of practical advantages. Founder broodstock originating from the wild population is conditioned to live in hatchery tanks under suitable environmental and feeding conditions and is induced to breed. The juveniles are grown to maturity and facilitated to spawn in captivity to close the life cycle in the hatchery. This experiment was carried out on tiger grouper (Epinephelus ...

  11. Vibrios associated with Litopenaeus vannamei larvae, postlarvae, broodstock, and hatchery probionts

    OpenAIRE

    Vandenberghe, J.; Verdonck, L.; Robles-Arozarena, R.; Rivera, G. (Gildardo); Bolland, A.; Balladares, M.; Gomez-Gil, B.; Calderon, J; Sorgeloos, P.; Swings, J.

    1999-01-01

    Several bacteriological surveys were performed from 1994 to 1996 at different Litopenaeus vannamei hatcheries (in Ecuador) and shrimp farms (in Mexico). Samples were taken from routine productions of healthy and diseased L. vannamei larvae, postlarvae, and their culture environment and from healthy and diseased juveniles and broodstock. In Ecuador, the dominant bacterial flora associated with shrimp larvae showing symptoms of zoea 2 syndrome, mysis mold syndrome, and bolitas syndrome has been...

  12. Vibrios Associated with Litopenaeus vannamei Larvae, Postlarvae, Broodstock, and Hatchery Probionts

    OpenAIRE

    Vandenberghe, Johan; Verdonck, Linda; Robles-Arozarena, Rocio; Rivera, Gabriel; Bolland, Annick; Balladares, Marcos; Gomez-Gil, Bruno; Calderon, Jorge; Sorgeloos, Patrick; Swings, Jean

    1999-01-01

    Several bacteriological surveys were performed from 1994 to 1996 at different Litopenaeus vannamei hatcheries (in Ecuador) and shrimp farms (in Mexico). Samples were taken from routine productions of healthy and diseased L. vannamei larvae, postlarvae, and their culture environment and from healthy and diseased juveniles and broodstock. In Ecuador, the dominant bacterial flora associated with shrimp larvae showing symptoms of zoea 2 syndrome, mysis mold syndrome, and bolitas syndrome has been...

  13. Snake River Sockeye Salmon Captive Broodstock; Research Element, 1993 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Keith A.

    1995-12-01

    In 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. Initial steps to recover the species include the establishment of captive broodstocks at the Eagle Fish Hatchery in Eagle, Idaho. Research and recovery activities for sockeye conducted by the Idaho Department of Fish and Game during the period of April 1993 to April 1994 are covered by this report. Eight anadromous adults (two female and six male) returned to the Redfish Lake Creek trap this year and were spawned at the Sawtooth Hatchery near Stanley, Idaho. Fecundity was 3160 for each female. The mean fertilization rate was 52% for female {open_quotes}A{close_quotes} and 65% for female {open_quotes}B.{close_quotes} Captive broodstock also spawned as well as residual sockeye captured in a Merwin trap in Redfish Lake. Spawning data from 72 fish spawned during this period is included in this report. Captive broodstock also matured later than normal (winter and spring 1994). Fish were spawned and samples were taken to investigate reasons for poor fertilization rates. Twenty-four out migrants of 1991 were selected for return to Redfish Lake for volitional spawning. Releases were made in August of 1993. All fish were implanted with sonic tags and tracking of this group began soon after the release to identify spawning-related activities. A research project is being conducted on captive broodstock diets. The project will investigate the effect of diet modification on spawn timing, gamete quality, and fertilization rates. A second project used ultrasound to examine fish for sexual maturity. The goal was to obtain a group a fish to be released f or volitional spawning. A total of 44 fish were found to be mature. The performance of all captive groups held at Eagle are included in this report.

  14. Genetic variability of broodstocks of Tambaqui (Teleostei – Characidae from the northeast region of Brazil

    Directory of Open Access Journals (Sweden)

    Nelson Mauricio Lopera-Barrero

    2015-12-01

    Full Text Available The objective of this experiment was to evaluate the genetic diversity within three Tambaqui broodstocks (Colossoma macropomum. Eight primers were used to analyze 67 individuals collected from three fish farming in the municipalities: Porto Real do Colégio – Alagoas (PRC, Araujo 1 – Sergipe (AR1 and Araujo 2 – Sergipe (AR2, in Brazil. Differences in the frequencies of 88 fragments and four exclusive fragments in PRC were found. High polymorphism values (from 54.38% to 64.38% and Shannon´s index (from 0.33 to 0.37 were observed. The AMOVA showed that high variation is within each broodstock. The identity and the genetic distance among the groups ranged from 0.845 to 0.975 and from 0.025 to 0.156 respectively, and the shortest distance was found in the groups PRC x AR1 and PRC x AR2. The genetic differentiation ranged from lower to higher (Fst = 0.03 and 0.178 as well as the migratory number per generation (Nm = 5.07 to 12.8. In general, the broodstocks had high intra-population variability, and high differentiation and genetic distance within themselves.

  15. Conditioning of broodstock of tiger grouper, Epinephelus fuscoguttatus, in a recirculating aquaculture system

    Directory of Open Access Journals (Sweden)

    Saleem Mustafa

    2015-11-01

    Full Text Available Closing the cycle of commercial species of fish in a recirculating aquaculture system is gaining importance for a number of practical advantages. Founder broodstock originating from the wild population is conditioned to live in hatchery tanks under suitable environmental and feeding conditions and is induced to breed. The juveniles are grown to maturity and facilitated to spawn in captivity to close the life cycle in the hatchery. This experiment was carried out on tiger grouper (Epinephelus fuscoguttatus. After preliminary observations, it was possible to identify appropriate environmental conditions in terms of water quality parameters, volume of broodstock tanks and ration. Growth was nearly isometric (growth exponent = 2.9185 and the condition factor = 1.86. This reflected good management conditions. Cues that trigger sex reversal in this protogynous fish in the hatchery were different from those that operate in nature. It appears that the differentiation of some individuals of a cohort into male sex is linked to socio-demographic cues as well as internal condition of the fish because it related to age and physiological condition. This view was reinforced by a lack of response in young fish to similar cues. The information generated through this study defines what is required for optimum conditioning of tiger grouper broodstock and explains the cues involved in sex differentiation.

  16. Practical Programming with Higher-Order Encodings and Dependent Types

    DEFF Research Database (Denmark)

    Poswolsky, Adam; Schürmann, Carsten

    2008-01-01

    , tedious, and error-prone. In this paper, we describe the underlying calculus of Delphin. Delphin is a fully implemented functional-programming language supporting reasoning over higher-order encodings and dependent types, while maintaining the benefits of HOAS. More specifically, just as representations...... utilizing HOAS free the programmer from concerns of handling explicit contexts and substitutions, our system permits programming over such encodings without making these constructs explicit, leading to concise and elegant programs. To this end our system distinguishes bindings of variables intended...... for instantiation from those that will remain uninstantiated, utilizing a variation of Miller and Tiu’s ∇-quantifier [1]....

  17. Dependable software through higher-order strategic programming.

    Energy Technology Data Exchange (ETDEWEB)

    Winter, Victor Lono (University of Nebraska at Omaha); Fraij, Fares (University of Texas at El Paso); Roach, Steve (University of Texas at El Paso)

    2004-03-01

    Program transformation is a restricted form of software construction that can be amenable to formal verification. When successful, the nature of the evidence provided by such a verification is considered strong and can constitute a major component of an argument that a high-consequence or safety-critical system meets its dependability requirements. This article explores the application of novel higher-order strategic programming techniques to the development of a portion of a class loader for a restricted implementation of the Java Virtual Machine (JVM). The implementation is called the SSP and is intended for use in high-consequence safety-critical embedded systems. Verification of the strategic program using ACL2 is also discussed.

  18. HUFA levels in eggs of wild and cultured broodstock of Macrobrachium rosenbergii

    OpenAIRE

    Lavens, P.; Piyatiratitivorakul, S.; Menasveta, P.; Sorgeloos, P

    1991-01-01

    The variation in egg quality, i.e. the potential of the egg to produce viable fry, is still a limiting factor in the commercial production of marine fish and crustacean fry. Better knowledge in this field would contribute to improved and especially more consistent hatchery outputs and to the development of more suitable broodstock diets. So far, objective criteria to evaluate egg quality are scarce. However, it is very likely that the nutrient composition of the eggs may be a good indicator f...

  19. Milt quality and spermatozoa morphology of captive Brycon siebenthalae (Eigenmann) broodstock

    DEFF Research Database (Denmark)

    Cruz-Casallas, Pablo E.; Lombo-Rodríguez, Dora A.; Velasco-Santamaría, Yohana M.

    2005-01-01

    collected for each male was 1.8 mL and the sperm concentration was 13.99 spermatozoa/mL. Spermatocrit (41.5%) was positively associated (r2: 0.30) with sperm density calculated using a corpuscle counting chamber. Sperm motility was 88% and the average duration of forward motility was 41 s. Fertilization...... rate was 84% and there was no association between this trait and sperm motility (r2: 0.009) or with sperm density (r2: 0.073). These results suggest that captive B. siebenthalae broodstock can be reproduced successfully....

  20. SEECAL: Program to calculate age-dependent specific effective energies

    International Nuclear Information System (INIS)

    This report describes the computer program SEECAL, which calculates specific effective energies (SEE) to specified target regions for ages newborn, 1 y, 5 y, 10 y, 15 y, a 70-kg adult male, and a 58-kg adult female. The dosimetric methodology is that of the International Commission on Radiological Protection (ICRP) and is generally consistent with the schema of the Medical Internal Radiation Dose committee of the US Society of Nuclear Medicine. Computation of SEEs is necessary in the computation of equivalent dose rate in a target region, for occupational or public exposure to radionuclides taken into the body. Program SEECAL replaces the program SEE that was previously used by the Dosimetry Research Group at Oak Ridge National Laboratory. The program SEE was used in the dosimetric calculations for occupational exposures for ICRP Publication 30 and is limited to adults. SEECAL was used to generate age-dependent SEEs for ICRP Publication 56, Part 1. SEECAL is also incorporated into DCAL, a radiation dose and risk calculational system being developed for the Environmental Protection Agency. Electronic copies of the program and data files and this report are available from the Radiation Shielding Information Center at Oak Ridge National Laboratory

  1. [Effectiveness evaluation of the drug dependency outpatient program "STEM"].

    Science.gov (United States)

    Kondo, Ayumi; Satou, Yoshitaka; Matsumoto, Toshihiko

    2016-02-01

    A cognitive behavioral therapy program entitled "STEM" was implemented with 42 drug dependent outpatients at Okayama Psychiatric Medical Center. Characteristics of 1 group who completed the program were examined, with the effectiveness of the program evaluated through monitoring longitudinal changes over a period of 8.5 months. Results showed that the percentage of patients who completed the program was 52.4% (22 out of 42 people), those who completed had a longer educational history than the dropouts, a high proportion of those who completed held some form of employment and that their motivation to recover was high. Evaluation results of the program effectiveness showed significant improvement in short-term drug self-efficacy, with a tendency for later improvement in feelings and emotions also observed. While a certain level of effectiveness was proven, approximately half the group dropped out; so it is necessary to consider alternative options at an early stage for participants with a high risk of dropout, such as strengthening individual support based on their specific characteristics. PMID:27295822

  2. Complexity of Data Dependence problems for Program Schemas with Concurrency

    CERN Document Server

    Danicic, Sebastian; Laurence, Michael R

    2010-01-01

    The problem of deciding whether one point in a program is data dependent upon another is fundamental to program analysis and has been widely studied. In this paper we consider this problem at the abstraction level of program schemas, in which computations occur in the Herbrand domain of terms and predicate symbols, which represent arbitrary predicate functions, are allowed. Given a vertex l in the flowchart of a schema S having only equality assignments and variables v,w, we show that it is PSPACE-hard to decide whether there exists an execution of a program defined by S in which v holds the initial value of w at at least one occurrence of l on the path of execution, with membership in PSPACE holding provided there is a constant upper bound on the arity of any predicate in S. We also consider the `dual' problem in which v is required to hold the initial value of w at every occurrence of l, for which the analogous results hold. Additionally, the former problem for programs with non-deterministic branching (in ...

  3. Example of the application the microsatellite DNA fragments in the study of farmed European catfish (Silurus glanis, L. broodstock

    Directory of Open Access Journals (Sweden)

    Kuciñski Marcin

    2015-06-01

    Full Text Available European catfish, Silurus glanis L., is the second largest freshwater fish in Europe. The species is very popular among the farmers, as it is one of the most promising European aquaculture species. Despite the growing importance of European catfish in freshwater aquaculture, the genetic data available on this species are still limited. The main purpose of the present study was to develop a reliable, feasible genetic protocol for future studies on European catfish populations and broodstocks in Poland. The genetic characteristics of the tested fish group were based on genetic parameters such as the polymorphism information content (PIC, the effective population size (Ne, the inbreeding coefficient (Fis, and the Garza-Williamson index (M, among others. Additionally, the potential effects of a genetic bottleneck on the genetic variation of the broodstock were examined. The genetic analysis protocol described in this study can be used to establish genetic-based records for European catfish broodstocks, including for sperm cryobanking. This approach will be useful for elaborating the selection procedures that allow for optimal assemblages of spawning pairs in artificial reproduction. The application of the genetic analysis protocol in practice will permit maintaining high quality in European catfish broodstocks.

  4. Role of mecp2 in experience-dependent epigenetic programming.

    Science.gov (United States)

    Zimmermann, Christoph A; Hoffmann, Anke; Raabe, Florian; Spengler, Dietmar

    2015-01-01

    Mutations in the X-linked gene MECP2, the founding member of a family of proteins recognizing and binding to methylated DNA, are the genetic cause of a devastating neurodevelopmental disorder in humans, called Rett syndrome. Available evidence suggests that MECP2 protein has a critical role in activity-dependent neuronal plasticity and transcription during brain development. Moreover, recent studies in mice show that various posttranslational modifications, notably phosphorylation, regulate Mecp2's functions in learning and memory, drug addiction, depression-like behavior, and the response to antidepressant treatment. The hypothalamic-pituitary-adrenal (HPA) axis drives the stress response and its deregulation increases the risk for a variety of mental disorders. Early-life stress (ELS) typically results in sustained HPA-axis deregulation and is a major risk factor for stress related diseases, in particular major depression. Interestingly, Mecp2 protein has been shown to contribute to ELS-dependent epigenetic programming of Crh, Avp, and Pomc, all of these genes enhance HPA-axis activity. Hereby ELS regulates Mecp2 phosphorylation, DNA binding, and transcriptional activities in a tissue-specific and temporospatial manner. Overall, these findings suggest MECP2 proteins are so far underestimated and have a more dynamic role in the mediation of the gene-environment dialog and epigenetic programming of the neuroendocrine stress system in health and disease. PMID:25756305

  5. Role of Mecp2 in Experience-Dependent Epigenetic Programming

    Directory of Open Access Journals (Sweden)

    Christoph A. Zimmermann

    2015-03-01

    Full Text Available Mutations in the X-linked gene MECP2, the founding member of a family of proteins recognizing and binding to methylated DNA, are the genetic cause of a devastating neurodevelopmental disorder in humans, called Rett syndrome. Available evidence suggests that MECP2 protein has a critical role in activity-dependent neuronal plasticity and transcription during brain development. Moreover, recent studies in mice show that various posttranslational modifications, notably phosphorylation, regulate Mecp2’s functions in learning and memory, drug addiction, depression-like behavior, and the response to antidepressant treatment. The hypothalamic-pituitary-adrenal (HPA axis drives the stress response and its deregulation increases the risk for a variety of mental disorders. Early-life stress (ELS typically results in sustained HPA-axis deregulation and is a major risk factor for stress related diseases, in particular major depression. Interestingly, Mecp2 protein has been shown to contribute to ELS-dependent epigenetic programming of Crh, Avp, and Pomc, all of these genes enhance HPA-axis activity. Hereby ELS regulates Mecp2 phosphorylation, DNA binding, and transcriptional activities in a tissue-specific and temporospatial manner. Overall, these findings suggest MECP2 proteins are so far underestimated and have a more dynamic role in the mediation of the gene-environment dialog and epigenetic programming of the neuroendocrine stress system in health and disease.

  6. Broodstock management of the fine flounder Paralichthys adspersus (Steindachner, 1867) using recirculating aquaculture systems

    OpenAIRE

    Lili Carrera; Noemí Cota; Melissa Montes; Enrique Mateo; Verónica Sierralta; Teresa Castro; Angel Perea; Cristian Santos; Christian Catcoparco; Carlos Espinoza

    2013-01-01

    The present study describes the methodology used at IMARPE for the capture, acclimation and management of P. adspersus broodstock using recirculating aquaculture systems (RAS). RAS improved the water quality and maintained the environmental parameters during the acclimation period, temperature (17.2±1°C), oxygen (8.1±0.7 mg L-1), pH (7.3±0.2), ammonia (0.004±0.003 mg L-1), nitrite (0.52±0.2 mg L-1) and nitrate (3.45±2.6 mg L-1). Fish began to be fed normally from day 15 post-capture, once or ...

  7. Computer optimization program finds values for several independent variables that minimize a dependent variable

    Science.gov (United States)

    Warech, E. J.

    1967-01-01

    Computer program finds values of independent variables which minimize the dependent variable. This optimization program has been used on the F-1 and J-2 engine programs to establish minimum film coolant requirements.

  8. Dependently typed array programs don't go wrong

    NARCIS (Netherlands)

    K. Trojahner; C. Grelck

    2008-01-01

    The array programming paradigm adopts multidimensional arrays as the fundamental data structures of computation. Array operations process entire arrays instead of just single elements. This makes array programs highly expressive and introduces data parallelism in a natural way. Array programming imp

  9. Dependently typed array programs don’t go wrong

    NARCIS (Netherlands)

    K. Trojahner; C. Grelck

    2007-01-01

    The array programming paradigm adopts multidimensional arrays as the fundamental data structures of computation. Array operations process entire arrays instead of just single elements. This makes array programs highly expressive and introduces data parallelism in a natural way. Array programming imp

  10. Dependently typed array programs don’t go wrong

    NARCIS (Netherlands)

    K. Trojahner; C. Grelck

    2009-01-01

    The array programming paradigm adopts multidimensional arrays as the fundamental data structures of computation. Array operations process entire arrays instead of just single elements. This makes array programs highly expressive and introduces data parallelism in a natural way. Array programming imp

  11. Growth of Nile tilapia post-larvae from broodstock fed diet with different levels of digestible protein and digestible energy

    Directory of Open Access Journals (Sweden)

    Silia Maria de Negreiros Sousa

    2013-08-01

    Full Text Available This study was carried out to evaluate the influence of different levels of digestible energy and digestible protein in diets of Nile tilapia (Oreochromis niloticus broodstock on offspring growth during sex reversal stage. A total of 2,700 post-larvae (8.2±0.001 mg derived from breeders fed nine diets with distinct levels of digestible protein (28, 34 and 40% DP and digestible energy (2,800; 3,400; and 4,000 kcal DE.kg-1 were stored in twenty-seven 70 L tanks. After 30 days of growth, their average final weight (AFW, g, average weight gain (AWG, g, final standard length (SL, cm, condition factor (CF, specific growth rate (SGR, %/day, stock uniformity (UNI, %, survival (SUR, % and sex reversal rate (SRR, % were measured. Although female nutrition is thought to influence the performance or quality of progeny during early life stages, no influence of diets supplied to broodstock was detected on any parameter. Nonetheless, the offspring presented commercially satisfactory growth rates. Thus, diets containing 28% of digestible protein and 2,800 kcal of digestible energy.kg of diet-1 can be used to feed Nile tilapia broodstock without jeopardizing offspring performance during the sex reversal phase.

  12. Multiple correlation computer program determines relationships between several independent and dependent variables

    Science.gov (United States)

    Kaspar, H.; Newsbaum, J. B.

    1967-01-01

    Relationships between independent and dependent variables are determined by multiple correlation computer program. This is applied to research and experimental design and development of complex hardware and components that require test programs.

  13. Effect of broodstock density on reproduction and juvenile culture of green buffalo leech, Hirudinea manillensis

    Directory of Open Access Journals (Sweden)

    Zulhisyam Abdul Kari

    2015-10-01

    Full Text Available In this study, the effect of the broodstock density on reproduction and juvenile culture of green buffalo leech, Hirudinea manillensis was examined with six different densities (5, 10, 15, 20, 25, and 30 ind tank-1. The number of cocoons produced was significantly different among the different densities (p = 0.00 after three months of culture. Although hatching rate was not (p = 0.354, the average number of hatchings per cocoon was also significantly different (p<0.05 with 5 ind tank-1 gave the highest number (6.61±1. The 25 ind tank-1 produced the highest mortality of parent leeches (67±13.16%. According to their length and diameter, the sizes of the cocoons were not significantly different among the treatments, with the 5 ind tank-1 having the largest cocoon of 22.19±0.92 mm and 13.25±0.07 mm, respectively. The wet weight of cocoons was significantly different at p<0.05 with the 5 ind tank-1 producing the heaviest cocoons of 1.26±0.11g compared to the 25 ind tank-1producing the lightest cocoons of 0.22±0.38 g.

  14. Broodstock management of the fine flounder Paralichthys adspersus (Steindachner, 1867 using recirculating aquaculture systems

    Directory of Open Access Journals (Sweden)

    Lili Carrera

    2013-03-01

    Full Text Available The present study describes the methodology used at IMARPE for the capture, acclimation and management of P. adspersus broodstock using recirculating aquaculture systems (RAS. RAS improved the water quality and maintained the environmental parameters during the acclimation period, temperature (17.2±1°C, oxygen (8.1±0.7 mg L-1, pH (7.3±0.2, ammonia (0.004±0.003 mg L-1, nitrite (0.52±0.2 mg L-1 and nitrate (3.45±2.6 mg L-1. Fish began to be fed normally from day 15 post-capture, once or twice a day using live fish (Odonthestes regia regia, Mugil cephalus, crustacean (Emerita analoga, fresh food (Engraulis ringens and Dosidicus gigas and artificial feed. A significant loss in the weight of the fish was registered during the first days of captivity, followed by a continuous increase in both sexes. The specific growth rate was positive from the third month of captivity, being the relative growth rate 24.5% and 16.2% in August 2010 in males and females, respectively. Different internal and external parasites were detected in the fish, being Entobdella sp. and Philometra sp. the prevailing parasites observed during samplings.

  15. Research on captive broodstock programs for pacific salmon: annual report, 2000-2001; ANNUAL

    International Nuclear Information System (INIS)

    It is not yet possible to define a feeding regimen for captively-reared stocks similar to their natural regimen that enhances the post-release fitness of juveniles and improves the reproductive performance of adults. In the natural environment, seasonal differences in food quality and quantity have profound effects on growth and 'wild' attributes, such as external coloration and fin quality. Formulating the right feeds for conservation fish held for long periods in captivity before release is more complicated than formulating diets for farm fish. Recent research in salmonid nutrition shows it is necessary to consider daily dietary protein intake and protein intake relative to total dietary energy level, rather than simply the levels of total dietary lipid

  16. Research on Captive Broodstock Programs for Pacific Salmon, 2000-2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Berejikian, Barry A.; Dittman, Andrew H. (National Marine Fisheries Service, Manchester, WA); Hardy, Ronald W. (University of Idaho, Hagerman Fish Culture Experiment Station, Hagerman, ID)

    2001-06-01

    It is not yet possible to define a feeding regimen for captively-reared stocks similar to their natural regimen that enhances the post-release fitness of juveniles and improves the reproductive performance of adults. In the natural environment, seasonal differences in food quality and quantity have profound effects on growth and 'wild' attributes, such as external coloration and fin quality. Formulating the right feeds for conservation fish held for long periods in captivity before release is more complicated than formulating diets for farm fish. Recent research in salmonid nutrition shows it is necessary to consider daily dietary protein intake and protein intake relative to total dietary energy level, rather than simply the levels of total dietary lipid.

  17. Fast and Cache-Oblivious Dynamic Programming with Local Dependencies

    DEFF Research Database (Denmark)

    Bille, Philip; Stöckel, Morten

    2012-01-01

    -oblivious algorithm for this type of local dynamic programming suitable for comparing large-scale strings. Our algorithm outperforms the previous state-of-the-art solutions. Surprisingly, our new simple algorithm is competitive with a complicated, optimized, and tuned implementation of the best cache-aware algorithm...

  18. A Qualitative Study of Tobacco Dependence Treatment in 19 US Dental Hygiene Programs

    OpenAIRE

    Koerber, Anne; Davis, Joan M.; Newton, Nancy A.

    2012-01-01

    Introduction The US Public Health Service calls for health professionals to provide tobacco dependence counseling for patients. The purpose of this study was to understand how dental hygiene programs make decisions about and provide training for tobacco dependence counseling to help them graduate more fully competent hygienists. Methods We conducted interviews (N = 32) with mainly program and clinic directors from 19 US dental hygiene education programs for this qualitative case study. We exp...

  19. Genetic variation in the mitochondrial genome of the giant grouper Epinephelus lanceolatus (Bloch, 1790 and its application for the identification of broodstock

    Directory of Open Access Journals (Sweden)

    Seng S. Cheng

    2015-11-01

    Full Text Available Mitochondrial DNA (mtDNA markers are ideal for the validation of maternal inheritance and the identification of brood-stock in aquaculture breeding programs. The complete mitochondrial genomes of 11 species of grouper are currently available at the GenBank. This study was directed towards the characterization of mtDNA loci which can be applied for identification of interspecific F1 hybrids developed from Epinephelus fuscoguttatus and Epinephelus lanceolatus in aquaculture breeding programs. DNA was extracted from the fin clip of one specimen of E. lanceolatus which the source of sperm for the artificial spawning of the interspecific F1 hybrid E. fuscoguttatus × E. lanceolatus. Specific primers were designed to amplify the DNA after comparative analysis of the mtDNA genomes available at the GenBank. The primers were applied to test for cross-amplification in F1 hybrids as well as in the maternal parent E. fuscoguttatus (Forsskål, 1775 and the genetically related species Epinephelus coioides and Epinephelus corallicola (Valenciennes, 1828. DNA sequence analysis revealed that the Malaysian variety of E. lanceolatus exhibited variation at 11 of the 13 ORFs when compared to the variety from Taiwan. A distinct segmented duplication was observed in the D-loop region which was determined to be unique to the E. lanceolatus specimen obtained from Sabah, Malaysia. Cross amplification of mtDNA loci in the groupers E. fuscoguttatus, E. coioides, E. corallicola and the F1 hybrid of E. fuscoguttatus × E. lanceolatus revealed distinct profiles for each of the species with a clear indication that mtDNA were inherited from the maternal parent of the F1 hybrid.. mtDNA loci can be applied by fish breeders to determine interspecific hybridization events.

  20. Research Advances in Functions of Vitamins on Broodstock Nutrition%维生素在亲鱼营养中的研究进展

    Institute of Scientific and Technical Information of China (English)

    肖登元; 梁萌青

    2012-01-01

    As essential micronutrients for fish, vitamins play a very important role in broodstock nutrition. This article summarized the research results of vitamin nutrition in broodstock in recent several decades, and elabora-ted on the physiological role of fat-soluble vitamins and water-soluble vitamins in terms of the broodstock' s go-nad development, fecundity, quality of sperm and ovum, embryo developments and larval survival rate. The article also explained the physiological function of vitamins A, C and E in detail on the broodstock nutrition.%维生素作为鱼类必不可少的微量营养素,其在亲鱼营养中占有非常重要的地位.本文总结了近几十年亲鱼的维生素营养研究成果,阐述了脂溶性维生素和水溶性维生素在亲鱼性腺发育、繁殖力、精卵质量、胚胎发育和仔鱼成活率等方面的生理作用,其中对维生素A、维生素C、维生素E的生理作用进行了较为详尽的阐明.

  1. Participation Rates in the Aid to Families with Dependent Children Program: Trends for 1967 through 1984.

    Science.gov (United States)

    Ruggles, Patricia; Michel, Richard C.

    This report examines participation rates in the Aid to Families with Dependent Children (AFDC) program. TRIM2, a microsimulation model that simulated the eligibility and benefit rules of the AFDC program on a state-by-state basis, showed that there had been a dramatic decline after 1981 in the rate at which AFDC families were applying for and…

  2. Wisconsin's Aid to Families with Dependent Children and Child Support Enforcement Programs Could Be Improved.

    Science.gov (United States)

    General Accounting Office, Washington, DC.

    This report from the General Accounting Office reviews selected aspects of Wisconsin's Aid to Families with Dependent Children (AFDC) program. Chapter 1 describes AFDC and specifies the scope of the program review. In Chapter 2 the potential for increasing child support collections from parents is explored. Actions which could increase collections…

  3. The Minnesota model treatment for substance dependence: program evaluation in a Swedish setting

    OpenAIRE

    Bodin, Maria

    2006-01-01

    The Minnesota model treatment for substance dependence is a group-based psychosocial intervention program that rests on the principles and twelve-step program of Alcoholics Anonymous (AA). The model was introduced to Sweden in 1983-84, and is currently used as the main treatment method in twenty-five percent of the addiction treatment units in the country. This thesis describes the results of a program evaluation in one private Minnesota model setting, with the general aims ...

  4. Grande Ronde Basin Chinook Salmon Captive Brood and Conventional Supplementation Program, 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Carmichael, Richard W. (Oregon Department of Fish and Wildlife, La Grande, OR)

    2003-03-01

    Endangered Species Permit Number 1011 (formerly Permit No. 973) authorizes ODFW to take listed spring chinook salmon juveniles from Catherine Creek (CC), Lostine River (LR) and Grande Ronde River (GR) for research and enhancement purposes. Modification 2 of this permit authorizes ODFW to take adults for spawning and the production and release of smolts for the Captive and Conventional broodstock programs. This report satisfies the requirement that an annual report be submitted. Herein we report on activities conducted and provide cursory data analyses for the Grande Ronde spring chinook salmon Captive and Conventional broodstock projects from 1 January-31 December 2000.

  5. Grande Ronde Basin Chinook Salmon Captive Brood and Conventional Supplementation Programs, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Carmichael, Richard W. (Oregon Department of Fish and Wildlife, La Grande, OR)

    2003-03-01

    Endangered Species Permit Number 1011 (formerly Permit No. 973) authorizes ODFW to take listed spring chinook salmon juveniles from Catherine Creek (CC), Lostine River (LR) and Grande Ronde River (GR) for research and enhancement purposes. Modification 2 of this permit authorizes ODFW to take adults for spawning and the production and release of smolts for the Captive and Conventional broodstock programs. This report satisfies the requirement that an annual report be submitted. Herein we report on activities conducted and provide cursory data analyses for the Grande Ronde spring chinook salmon Captive and Conventional broodstock projects from 1 January-31 December 2001.

  6. Dependent-Chance Programming Models for Capital Budgeting in Fuzzy Environments

    Institute of Scientific and Technical Information of China (English)

    LIANG Rui; GAO Jinwu

    2008-01-01

    Capital budgeting is concerned with maximizing the total net profit subject to budget constraints by selecting an appropriate combination of projects. This paper presents chance maximizing models for capital budgeting with fuzzy input data and multiple conflicting objectives. When the decision maker sets a prospec-tive profit level and wants to maximize the chances of the total profit achieving the prospective profit level, a fuzzy dependent-chance programming model, a fuzzy multi-objective dependent-chance programming model, and a fuzzy goal dependent-chance programming model are used to formulate the fuzzy capital budgeting problem. A fuzzy simulation based genetic algorithm is used to solve these models. Numerical examples are provided to illustrate the effectiveness of the simulation-based genetic algorithm and the po-tential applications of these models.

  7. Optimal Control for Industrial Sucrose Crystallization with Action Dependent Heuristic Dynamic Programming

    OpenAIRE

    Xiaofeng Lin; Heng Zhang; Li Wei; Huixia Liu

    2009-01-01

    This paper applies a neural-network-based approximate dynamic programming (ADP) method, namely, the action dependent heuristic dynamic programming (ADHDP), to an industrial sucrose crystallization optimal control problem. The industrial sucrose crystallization is a nonlinear and slow time-varying process. It is quite difficult to establish a precise mechanism model of the crystallization, because of complex internal mechanism and interacting variables. We developed a neural network model of t...

  8. An Introduction to Programming and Proving with Dependent Types in Coq

    OpenAIRE

    Adam Chlipala

    2010-01-01

    Computer proof assistants vary along many dimensions. Among the mature implementations, the Coq system is distinguished by two key features. First, we have support for programming with dependent types in the tradition of type theory, based on dependent function types and inductive type families. Second, we have a domain-specific language for coding correct-by-construction proof automation. Though the Coq user community has grown quite large, neither of the aspects I highlight is widely used. ...

  9. GENETICS AND GENOMICS - INTEGRATION OF MOLECULAR GENETICS INTO A BREEDING PROGRAM FOR RAINBOW TROUT

    Science.gov (United States)

    At the National Center for Cool and Cold Water Aquaculture (US Department of Agriculture, Ag. Research Service) in Leetown, WV, we have a broodstock development program now entering the 2nd generation of family based selective breeding using expected breeding values (EBVs). Our major breeding objec...

  10. Tucannon River Spring Chinook Salmon Captive Brood Program, FY 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Bumgarner, Joseph D.; Gallinat, Michael P.

    2001-06-01

    This report summarizes the objectives, tasks, and accomplishments of the Tucannon River spring chinook captive brood program from program inception (1997) through April 2001. The WDFW initiated a captive broodstock program in 1997. The overall goal of the Tucannon River captive broodstock program is for the short-term, and eventually long-term, rebuilding of the Tucannon River spring chinook salmon run, with the hope that natural production will eventually sustain itself. The project goal is to rear captive salmon to adults, spawn them, rear their progeny, and release approximately 150,000 smolts annually into the Tucannon River between 2003-2007. These smolt releases, in combination with the current hatchery supplementation program (132,000 smolts), and wild production, is expected to produce 600-700 returning adult spring chinook to the Tucannon River each year from 2005-2010. The Master Plan, Environmental Assessment, and most facility modifications at LFH were completed for the Tucannon River spring chinook captive broodstock program during FY2000 and FY2001. DNA samples collected since 1997 have been sent to the WDFW genetics lab in Olympia for baseline DNA analysis. Results from the genetic analysis are not available at this time. The captive broodstock program is planned to collect fish from five (1997-2001) brood years (BY). The captive broodstock program was initiated with 1997 BY juveniles, and the 2000 BY fish have been selected. As of April 30, 2001, WDFW has 172 BY 1997, 262 BY 1998, 407 BY 1999, and approximately 1,190 BY 2000 fish on hand at LFH. Twelve of 13 mature 97 BY females were spawned in 2000. Total eggtake was 14,813. Mean fecundity was 1,298 eggs/female based on 11 fully spawned females. Egg survival to eye-up was 47.3%. This low survival was expected for three year old captive broodstock females. As of April 30, 2001, WDFW has 4,211 captive broodstock progeny on hand. These fish will be tagged with blank wire tag without fin clips and

  11. Tucannon River spring chinook salmon captive brood program, FY 2000 annual report; ANNUAL

    International Nuclear Information System (INIS)

    This report summarizes the objectives, tasks, and accomplishments of the Tucannon River spring chinook captive brood program from program inception (1997) through April 2001. The WDFW initiated a captive broodstock program in 1997. The overall goal of the Tucannon River captive broodstock program is for the short-term, and eventually long-term, rebuilding of the Tucannon River spring chinook salmon run, with the hope that natural production will eventually sustain itself. The project goal is to rear captive salmon to adults, spawn them, rear their progeny, and release approximately 150,000 smolts annually into the Tucannon River between 2003-2007. These smolt releases, in combination with the current hatchery supplementation program (132,000 smolts), and wild production, is expected to produce 600-700 returning adult spring chinook to the Tucannon River each year from 2005-2010. The Master Plan, Environmental Assessment, and most facility modifications at LFH were completed for the Tucannon River spring chinook captive broodstock program during FY2000 and FY2001. DNA samples collected since 1997 have been sent to the WDFW genetics lab in Olympia for baseline DNA analysis. Results from the genetic analysis are not available at this time. The captive broodstock program is planned to collect fish from five (1997-2001) brood years (BY). The captive broodstock program was initiated with 1997 BY juveniles, and the 2000 BY fish have been selected. As of April 30, 2001, WDFW has 172 BY 1997, 262 BY 1998, 407 BY 1999, and approximately 1,190 BY 2000 fish on hand at LFH. Twelve of 13 mature 97 BY females were spawned in 2000. Total eggtake was 14,813. Mean fecundity was 1,298 eggs/female based on 11 fully spawned females. Egg survival to eye-up was 47.3%. This low survival was expected for three year old captive broodstock females. As of April 30, 2001, WDFW has 4,211 captive broodstock progeny on hand. These fish will be tagged with blank wire tag without fin clips and

  12. Optimal Control for Industrial Sucrose Crystallization with Action Dependent Heuristic Dynamic Programming

    Directory of Open Access Journals (Sweden)

    Xiaofeng Lin

    2009-10-01

    Full Text Available This paper applies a neural-network-based approximate dynamic programming (ADP method, namely, the action dependent heuristic dynamic programming (ADHDP, to an industrial sucrose crystallization optimal control problem. The industrial sucrose crystallization is a nonlinear and slow time-varying process. It is quite difficult to establish a precise mechanism model of the crystallization, because of complex internal mechanism and interacting variables. We developed a neural network model of the crystallization based on the data from the actual sugar boiling process of sugar refinery. The ADHDP is a learningand approximation-based approach which can solve the optimization control problem of nonlinear system. The paper covers the basic principle of this learning scheme and the design of neural network controller based on the approach. The result of simulation shows the controller based on action dependent heuristic dynamic programming approach can optimize industrial sucrose crystallization.

  13. Introduction to the AFDC program. Aid to Families with Dependent Children.

    Science.gov (United States)

    Page, S B; Larner, M B

    1997-01-01

    This journal issue discusses the policy challenges of helping parents move from welfare to work. As a foundation, this introductory article explains the federal-state program of cash assistance called Aid to Families with Dependent Children (AFDC), to which the term welfare refers in most of these articles. While a number of other social programs are sometimes included under the umbrella of welfare-such as the Supplemental Security Income program for the disabled, food stamps, and Medicaid-the program that has drawn the most public scrutiny and negative attention, and the centerpiece of the 1996 welfare reform legislation, is AFDC. This article explains the basic structure of the AFDC program, including eligibility criteria and benefits; discusses the characteristics of families that have received AFDC; describes trends in the program's size and cost from the 1970s to 1996; and indicates the major ways in which the block grant established in the 1996 welfare reform legislation compares to the AFDC program that it replaced. PMID:9170729

  14. Spatially dependent burnup implementation into the nodal program based on the finite element response matrix method

    International Nuclear Information System (INIS)

    In this work a spatial burnup scheme and feedback effects has been implemented into the FERM ( 'Finite Element Response Matrix' )program. The spatially dependent neutronic parameters have been considered in three levels: zonewise calculation, assembly wise calculation and pointwise calculation. Flux and power distributions and the multiplication factor were calculated and compared with the results obtained by CITATIOn program. These comparisons showed that processing time in the Ferm code has been hundred of times shorter and no significant difference has been observed in the assembly average power distribution. (Author)

  15. The Development of Sexual Knowledge Test Depending on Sex Education Programs

    OpenAIRE

    Kutlu, Ömer; Ankara Üniversitesi, Eğitim Bilimleri Fakültesi; Çok, Figen; Ankara Üniversitesi, Eğitim Bilimleri Fakültesi

    2002-01-01

    This study purposes to develop a sexual knowledge test to be used for evaluating a sexuality education program for 12-14 year-old adolescents. Depending on the content of the program, multiple choice test items (questions) were prepared. These items were sent to a group of raters in order to be critized in terms of content, language and pyschometric qualities and their feedback was considered. The test was reviewed according to the feedback and administered to 255 adolescents (12-14 years old...

  16. An Introduction to Programming and Proving with Dependent Types in Coq

    Directory of Open Access Journals (Sweden)

    Adam Chlipala

    2010-01-01

    Full Text Available Computer proof assistants vary along many dimensions. Among the mature implementations, the Coq system is distinguished by two key features. First, we have support for programming with dependent types in the tradition of type theory, based on dependent function types and inductive type families. Second, we have a domain-specific language for coding correct-by-construction proof automation. Though the Coq user community has grown quite large, neither of the aspects I highlight is widely used. In this tutorial, I aim to provide a pragmatic introduction to both, showing how they can bring significant improvements in productivity.

  17. Enabling Requirements-Based Programming for Highly-Dependable Complex Parallel and Distributed Systems

    Science.gov (United States)

    Hinchey, Michael G.; Rash, James L.; Rouff, Christopher A.

    2005-01-01

    The manual application of formal methods in system specification has produced successes, but in the end, despite any claims and assertions by practitioners, there is no provable relationship between a manually derived system specification or formal model and the customer's original requirements. Complex parallel and distributed system present the worst case implications for today s dearth of viable approaches for achieving system dependability. No avenue other than formal methods constitutes a serious contender for resolving the problem, and so recognition of requirements-based programming has come at a critical juncture. We describe a new, NASA-developed automated requirement-based programming method that can be applied to certain classes of systems, including complex parallel and distributed systems, to achieve a high degree of dependability.

  18. Evaluation of a Comprehensive Tobacco Dependence Treatment Program: Dental Students' Perceptions of Preparedness and Clinical Practice.

    Science.gov (United States)

    Mackie, Zainab F; Loewen, Jill M; Savaya, Mathew G

    2015-08-01

    The aims of this study were to assess dental students' perceptions of their preparedness for providing treatment for tobacco dependence and to determine if their training resulted in successful practice in the dental school clinic. Since the tobacco dependence treatment program began at the University of Detroit Mercy School of Dentistry, all third- and fourth-year dental students have been required to complete an online survey about their attitudes and experience with tobacco dependence treatment. This descriptive study and retrospective analysis utilized these survey data from the initiation of the program in fall 2002 through 2010 (615 third-year and 590 fourth-year students, for a total of 1,205, all of whom participated in the surveys). The results showed that most of the students believed they were at least adequately prepared to provide treatment. The majority said they ask patients about tobacco use and advise patients about its negative health consequences, yet the average of their perception of patient interest in quitting was below 18%. Although the students reported being at least adequately prepared to assess patient interest in quitting, their assessment was much lower than the nearly 70% of U.S. tobacco users that general studies have found are interested in quitting. These students' perception of such low patient interest reflects a misconception they may have about their own preparedness, and it suggests a barrier exists for them in providing effective tobacco dependence treatment services. This perception signals a need for curriculum and assessment changes to increase the effectiveness of this school's tobacco dependence treatment program. PMID:26246534

  19. Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.

    Science.gov (United States)

    Kress, Theresia R; Pellanda, Paola; Pellegrinet, Luca; Bianchi, Valerio; Nicoli, Paola; Doni, Mirko; Recordati, Camilla; Bianchi, Salvatore; Rotta, Luca; Capra, Thelma; Ravà, Micol; Verrecchia, Alessandro; Radaelli, Enrico; Littlewood, Trevor D; Evan, Gerard I; Amati, Bruno

    2016-06-15

    Tumors driven by activation of the transcription factor MYC generally show oncogene addiction. However, the gene expression programs that depend upon sustained MYC activity remain unknown. In this study, we employed a mouse model of liver carcinoma driven by a reversible tet-MYC transgene, combined with chromatin immunoprecipitation and gene expression profiling to identify MYC-dependent regulatory events. As previously reported, MYC-expressing mice exhibited hepatoblastoma- and hepatocellular carcinoma-like tumors, which regressed when MYC expression was suppressed. We further show that cellular transformation, and thus initiation of liver tumorigenesis, were impaired in mice harboring a MYC mutant unable to associate with the corepressor protein MIZ1 (ZBTB17). Notably, switching off the oncogene in advanced carcinomas revealed that MYC was required for the continuous activation and repression of distinct sets of genes, constituting no more than half of all genes deregulated during tumor progression and an even smaller subset of all MYC-bound genes. Altogether, our data provide the first detailed analysis of a MYC-dependent transcriptional program in a fully developed carcinoma and offer a guide to identifying the critical effectors contributing to MYC-driven tumor maintenance. Cancer Res; 76(12); 3463-72. ©2016 AACR. PMID:27197165

  20. [Risk/protective factors and prevention programs for drug dependence in Peru].

    Science.gov (United States)

    Cabanillas-Rojas, William

    2012-03-01

    Risk/ protective factors (RPF) are main elements for the analysis, understanding and formulation of answers for the prevention of drug dependences. The objective of this article is to present a literature review about the RPF and their implications in the design of preventive programs. It will focus on individual (genetic aspects, early experiences and psicosocial skills), family (parental control and monitoring, permissiveness, parenting styles), peer (group pressure and social norms) and communitarian (disorganization) RPF. On the other hand, the need of incorporating a multifactor conceptual framework for the preventive approach to drug dependences, articulating the intervention spaces (school, family and community), assuming and evolving perspective allowing the implementations of sustained actions is evidenced. On top, the implications for future research and public policy formulation are discussed. PMID:22510915

  1. Expressing Coarse-Grain Dependencies Among Tasks in Shared Memory Programs

    DEFF Research Database (Denmark)

    Larsen, Per; Karlsson, Sven; Madsen, Jan

    2011-01-01

    Designers of embedded systems face tight constraints on resources, response time and cost. The ability to analyze embedded systems is essential to timely delivery of new designs. Many analysis techniques model parallel programs as task graphs. Task graphs capture the worst-case execution times...... dependencies that do not occur at runtime. This lets tools compute more accurate task graphs from the annotated code. The correct use of the directives cannot be verified at compile time. Therefore, the check for correct use is done at runtime—not unlike dynamic array bounds checking in many languages...

  2. Gender differences in recovery consequences among heroin dependent patients after compulsory treatment programs.

    Science.gov (United States)

    Haifeng, Jiang; Di, Liang; Jiang, Du; Haiming, Sun; Zhikang, Chen; Liming, Fu; Min, Zhao

    2015-01-01

    Studies on recovery patterns and how baseline factors influence recovery consequences among heroin dependent patients have shown mixed results. This study is aimed at describing the gender differences in long-term recovery patterns and exploring the predictors of negative recovery consequences by gender among heroin dependent patients in Shanghai, China. At baseline, this study recruited 503 heroin dependent patients discharged from Shanghai compulsory rehabilitation facilities in 2007 and 2008. In this cohort study, the baseline data was then linked with participants' 5-year follow-up data from official records. Generalized Estimating Equations (GEE) were used to compare males with females in terms of the presence of negative consequences (incarceration, or readmission to compulsory treatment, or both), in the subsequent 5-years after their discharge from compulsory treatment. Ordinary least squares (OLS) regression was used to explore factors associated to the time length of negative consequences in 5 years after the discharge for males and females separately. Our findings indicate that female heroin dependent patients tend to have less negative recovery outcomes than male patients. Male patients with a life-time history of poly drug use and female patients with borderline personality disorder are especially at risk of incarceration and readmission into compulsory treatment programs. PMID:26644283

  3. Characterization of two Runx1-dependent nociceptor differentiation programs necessary for inflammatory versus neuropathic pain

    Directory of Open Access Journals (Sweden)

    Arber Silvia

    2010-07-01

    Full Text Available Abstract Background The cellular and molecular programs that control specific types of pain are poorly understood. We reported previously that the runt domain transcription factor Runx1 is initially expressed in most nociceptors and controls sensory neuron phenotypes necessary for inflammatory and neuropathic pain. Results Here we show that expression of Runx1-dependent ion channels and receptors is distributed into two nociceptor populations that are distinguished by persistent or transient Runx1 expression. Conditional mutation of Runx1 at perinatal stages leads to preferential impairment of Runx1-persistent nociceptors and a selective defect in inflammatory pain. Conversely, constitutive Runx1 expression in Runx1-transient nociceptors leads to an impairment of Runx1-transient nociceptors and a selective deficit in neuropathic pain. Notably, the subdivision of Runx1-persistent and Runx1-transient nociceptors does not follow the classical nociceptor subdivision into IB4+ nonpeptidergic and IB4- peptidergic populations. Conclusion Altogether, we have uncovered two distinct Runx1-dependent nociceptor differentiation programs that are permissive for inflammatory versus neuropathic pain. These studies lend support to a transcription factor-based distinction of neuronal classes necessary for inflammatory versus neuropathic pain.

  4. CREST : a computer program for the calculation of composition dependent self-shielded cross-sections

    International Nuclear Information System (INIS)

    A computer program CREST for the calculation of the composition and temperature dependent self-shielded cross-sections using the shielding factor approach has been described. The code includes the editing and formation of the data library, calculation of the effective shielding factors and cross-sections, a fundamental mode calculation to generate the neutron spectrum for the system which is further used to calculate the effective elastic removal cross-sections. Studies to explore the sensitivity of reactor parameters to changes in group cross-sections can also be carried out by using the facility available in the code to temporarily change the desired constants. The final self-shielded and transport corrected group cross-sections can be dumped on cards or magnetic tape in a suitable form for their direct use in a transport or diffusion theory code for detailed reactor calculations. The program is written in FORTRAN and can be accommodated in a computer with 32 K work memory. The input preparation details, sample problem and the listing of the program are given. (author)

  5. Avidity-dependent programming of autoreactive T cells in T1D.

    Directory of Open Access Journals (Sweden)

    Ivana Durinovic-Belló

    Full Text Available Fate determination for autoreactive T cells relies on a series of avidity-dependent interactions during T cell selection, represented by two general types of signals, one based on antigen expression and density during T cell development, and one based on genes that interpret the avidity of TCR interaction to guide developmental outcome. We used proinsulin-specific HLA class II tetramers to purify and determine transcriptional signatures for autoreactive T cells under differential selection in type 1 diabetes (T1D, in which insulin (INS genotypes consist of protective and susceptible alleles that regulate the level of proinsulin expression in the thymus. Upregulation of steroid nuclear receptor family 4A (NR4A and early growth response family genes in proinsulin-specific T cells was observed in individuals with susceptible INS-VNTR genotypes, suggesting a mechanism for avidity-dependent fate determination of the T cell repertoire in T1D. The NR4A genes act as translators of TCR signal strength that guide central and peripheral T cell fate decisions through transcriptional modification. We propose that maintenance of an NR4A-guided program in low avidity autoreactive T cells in T1D reflects their prior developmental experience influenced by proinsulin expression, identifying a pathway permissive for autoimmunity.

  6. PCR and probe-PCR assays to monitor broodstock Atlantic salmon (Salmo salar L.) ovarian fluid and kidney tissue for presence of DNA of the fish pathogen Renibacterium salmoninarum.

    Science.gov (United States)

    Miriam, A; Griffiths, S G; Lovely, J E; Lynch, W H

    1997-06-01

    A simple, rapid PCR assay for the identification of Renibacterium salmoninarum in Atlantic salmon (Salmo salar L.) tissues detected DNA extracted from between 4 and 40 bacterial cells. PCR was at least as sensitive as culture when it was used to identify subclinically infected fish experimentally challenged with R. salmoninarum. However, PCR identified much higher numbers of kidney tissue and ovarian fluid samples from commercially reared broodstock fish to be positive for R. salmoninarum than did culture. This difference may be due to the antibiotic chemotherapy of broodstock fish used by the industry in 1994 to control the vertical transmission of R. salmoninarum. A much closer relationship between PCR and culture results was observed for ovarian fluid samples collected from broodstock fish in 1993. Also, PCR scored a much higher percentage of kidney tissue samples than ovarian fluid samples from 1994 broodstock fish positive for R. salmoninarum, which may reflect the uneven distribution of the pathogen in different fish tissues. Inclusion of a nested probe to identify the PCR-positive 1994 ovarian fluid samples increased the sensitivity of detection to between one and four cells and the number of samples that scored positive by almost threefold. These data indicate that many infected ovarian fluid samples contained very low numbers of R. salmoninarum cells and, because almost all these samples were culture negative, that PCR may have detected dead or otherwise unculturable bacterial cells. PMID:9163437

  7. Relationship of Broodstock Weight and Hatching Yield of III. Generation (F3 Black Sea Trout (Salmo trutta labrax Pallas, 1814

    Directory of Open Access Journals (Sweden)

    Hakan Baki

    2015-07-01

    Full Text Available In this study, this was the aimed to determine the reproduction and hatching yields in different weight groups in hatchery origin rootstocks (F3 Black Sea trout (Salmo trutta labrax Pallas, 1814. In this study, the female fishes which produced from natural rootstock were used average weight 1437±134.6 g (Group I 2737±210.2 g (Group II and 3785±162.3 g (Group III. After the stripping process; according to the groups, were determined respectively eggs absolute fecundity (number of eggs/broodfish is average 2353±205, 5361±506, 6603±491, relative fecundity (number of eggs/kg is average1687±166, 1968±194, 1744±114. The egg diameter (mm 4.89±0.16, 5.28±0.07, 5.31±0.06 egg weight (mg 77±6, 90±4, 96±3 groups I., II. and III. respectively was calculated. The fertilization ratio (% 95.49±1.23, 96.49±1.14, 98.39±0.52, browse rate (% 79.97±5.36, 84.20±5.23, 94.70±1.50, has been identified. The output rate (% 60.57±7.86, 67.66±6.42, 84.83±3.09, the hatchery efficiency (% 58.14±7.95, 69.77±6.25, 83.51±3.29 was found. relative fecundity average value 168±160, 1968±194, 1744±114.The existence of relationship among the weight of the brood-stock, absolute fecundity (0.0198, 0.0012, 0.3499, and relative egg fecundity (0.3415, 0.0494, 0.00 was tested by regression analysis and consequently the difference between groups were significant. This was determined that between fish weight and absolute fecundity relationship is weak directly proportional for each group, between fish weight and relative fecundity is weak inversely proportional in Group I and II, the Group III is weak for directly proportional.

  8. Grande Ronde Basin Chinook Salmon Captive Brood and Conventional Supplementation Programs, 2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hoffnagle, Timothy L.; Hair, Don; Carmichael, Richard W. (Oregon Department of Fish and Wildlife, La Grande, OR)

    2004-07-01

    BPA Fish and Wildlife Program Project Number 1998-01-001 provides funding for the Grande Ronde Basin Spring Chinook Salmon Captive Broodstock Program. This report satisfies the requirement that an annual report be submitted for FY 2003. The Grande Ronde Basin Spring Chinook Salmon Captive Broodstock Project is designed to rapidly increase numbers of salmon in stocks that are in imminent danger of extirpation. Parr are captured in Catherine Creek, upper Grande Ronde River and Lostine River and reared to adulthood in captivity. Upon maturation, these fish are spawned (within stocks) and their progeny reared to smoltification before being released into the natal stream of their parents. This program is co-managed by ODFW, National Marine Fisheries Service, Nez Perce Tribe and Confederated Tribes of the Umatilla Indian Reservation. This report covers activities conducted and provides data analyses for the Grande Ronde Spring Chinook Salmon Captive broodstock Program from 1 January--31 December 2003. Since the fiscal year ends in the middle of the spawning period, an annual report based on calendar year is more logical. This document is the FY 2003 annual report. Detailed information on historic and present population status, project background, goals and objectives, significance to regional programs and relationships to other programs, methods and previous results are available in the 1995-2002 Project Status Report (Hoffnagle et al 2003).

  9. An Action Dependent Heuristic Dynamic Programming-controlled Superconducting Magnetic Energy Storage for Transient Stability Augmentation

    Science.gov (United States)

    Wang, Xinpu; Yang, Jun; Zhang, Xiaodong; Yu, Xiaopeng

    To enhance the stability of power system, the active power and reactive power can be absorbed from or released to Superconducting magnetic energy storage (SMES) unit according to system power requirements. This paper proposes a control strategy based on action dependent heuristic dynamic programing (ADHDP) which can control SMES to improve the stability of electric power system with on-line learning ability. Based on back propagation (BP) neural network, ADHDP approximates the optimal control solution of nonlinear system through iteration step by step. This on-line learning ability improves its performance by learning from its own mistakes through reinforcement signal from external environment, so that it can adjust the neural network weights according to the back propagation error to achieve optimal control performance. To investigate the effectiveness of the proposed control strategy, simulation tests are carried out in Matlab/Simulink. And a conventional Proportional-Integral (PI) controlled method is used to compare the performance of ADHDP. Simulation results show that the proposed controller demonstrates superior damping performance on power system oscillation caused by three-phase fault and wind power fluctuation over the PI controller.

  10. Action dependent heuristic dynamic programming based residential energy scheduling with home energy inter-exchange

    International Nuclear Information System (INIS)

    Highlights: • The algorithm is developed in the two-household energy management environment. • We develop the absent energy penalty cost for the first time. • The algorithm has ability to keep adapting in real-time operations. • Its application can lower total costs and achieve better load balancing. - Abstract: Residential energy scheduling is a hot topic nowadays in the background of energy saving and environmental protection worldwide. To achieve this objective, a new residential energy scheduling algorithm is developed for energy management, based on action dependent heuristic dynamic programming. The algorithm works under the circumstance of residential real-time pricing and two adjacent housing units with energy inter-exchange, which can reduce the overall cost and enhance renewable energy efficiency after long-term operation. It is designed to obtain the optimal control policy to manage the directions and amounts of electricity energy flux. The algorithm’s architecture is mainly constructed based on neural networks, denoting the learned characteristics in the linkage of layers. To get close to real situations, many constraints such as maximum charging/discharging power of batteries are taken into account. The absent energy penalty cost is developed for the first time as a part of the performance index function. When the environment changes, the residential energy scheduling algorithm gains new features and keeps adapting in real-time operations. Simulation results show that the developed algorithm is beneficial to energy conversation

  11. Approaching tobacco dependence in youngsters: impact of an interactive smoking cessation program in a population of Romanian adolescents

    OpenAIRE

    Trofor, Antigona; Mihaicuta, Stefan; Man, Milena Adina; MIRON Ramona; Esanu, Valentina; Trofor, Letitia

    2010-01-01

    Objectives: The main objective of this study was to investigate the effectiveness of an interactive smoking cessation program when first implemented in a naïve population of Romanian adolescents. The secondary objective was to assess youngsters\\' attitudes and beliefs towards tobacco dependence, their compliance to smoking cessation interventions and success rate of a standard smoking cessation pilot program. Materials and methods: A total of 231 subjects 14-19 years old particip...

  12. A Guide for the Management of Speical Education Programs. 4.0 Drug Information for Educators, Parents, and Students. Newday Operations Guide for Drug Dependent Minor Programs.

    Science.gov (United States)

    Santa Cruz County Superintendent of Schools, CA.

    Presented is the fourth component of a special day class program for drug dependent minors, Drug Information for Educators, Parents, and Students. The first section, intended for educators, includes a drug abuse chart, information on the drug subculture, information on patterns of drug abuse and misconceptions about drugs, and suggested activities…

  13. Reproductive broodstock performance and egg quality of wild-caught and first-generation domesticated Seriola rivoliana reared under same culture conditions

    Directory of Open Access Journals (Sweden)

    Marcos F Quiñones-Arreola

    2015-11-01

    Full Text Available Almaco jack, Seriola rivoliana as well as some related species is of great interest in marine fish aquaculture. However, there are few studies about their reproduction in captivity. In this research work, reproductive performance and egg quality in two groups of adult Seriola rivoliana, caught in the wild and domesticated-F1 analyzed and compared, reared under optimal maturation conditions in a commercial private Laboratory. A total of 28 wild adult (>5 kg were caught at La Paz Bay, Baja California Sur, Mexico, and 30 adult domesticated-F1 broodstock (>5 kg, were obtained from an original stock of 1,000 juveniles (3.5 g body weight produced at Kona Blue (Hawaii, USA sea farm. Fishes were transported to the Rancheros del Mar commercial private hatchery, where they were grown to adult size. Both groups were evaluated during eight months (May to December 2012 and compared in terms of reproduction performance (total number of spawning events, monthly spawning frequency, total number of eggs, total number of eggs per mL, and fertilization rate, egg biochemical composition (total proteins, total lipids, total carbohydrates, and triacylglycerides and egg diameter. Results indicated that wild caught broostock showed a better reproductive performance in terms of fertilization rate, total number of spawning, monthly spawning frequency and total number of eggs produced. However, biochemical composition and egg diameter did not show statistical differences (P < 0.05 between two groups. The reproductive performance of broodstock and quality of eggs analyzed in this study are important traits to improve the aquaculture management of this species.

  14. Does broodstock nutritional history affect the response of progeny to different first-feeding diets? A whole-body transcriptomic study of rainbow trout alevins.

    Science.gov (United States)

    Lazzarotto, Viviana; Corraze, Geneviève; Larroquet, Laurence; Mazurais, David; Médale, Françoise

    2016-06-01

    The whole-body transcriptome of trout alevins was characterised to investigate the effects of long-term feeding of rainbow trout broodstock females a diet free of fishmeal and fish oil on the metabolic capacities of progeny. Effects were studied before first feeding and after 3 weeks of feeding diets containing different proportions of marine and plant ingredients. Feeding alevins plant-based diets resulted in lower fish body weight, irrespective of maternal nutritional history. No differences in whole-body lipids were found between treatments, and the tissue fatty acid profile strongly reflected that of the respective broodstock or first-feeding diets. We showed that the maternal diet history did not significantly affect expressions of any genes before the first feeding. Interestingly, we found an effect of maternal nutritional history on gene expression in alevins after 3 weeks of feeding. The major differences in the transcriptome of alevins from plant-based diet-fed females compared with those from commercial-fed females were as follows: (i) down-regulation of genes involved in muscle growth/contraction and (ii) up-regulation of genes involved in carbohydrate and energy metabolism related to the delay in growth/development observed with plant-based diets. Our findings also showed an effect of the first-feeding diets, irrespective of maternal nutritional history. Specifically, the introduction of plant ingredients resulted in the up-regulation of genes involved in amino acid/protein and cholesterol metabolism and in differences in the expressions of genes related to carbohydrate metabolism. Information gained through this study opens up avenues for further reduction of marine ingredients in trout diets, including the whole rearing cycle. PMID:27112276

  15. Responses to Violence Related Questionnaires by Delinquent, Truant and State-Dependent Boys Receiving Treatment in an Extended Day Program

    Science.gov (United States)

    Polanksy, Marcia; Villanueva, Augusta M.; Bonfield, Jeffrey

    2008-01-01

    Violence among adolescent boys in impoverished urban areas is a major public health problem. We assessed violence-related attitudes and beliefs and exposures among 29 delinquent, 22 truant and 12 dependent of the state adolescent boys who attended an urban publicly funded extended day program. One purpose of this study was to assess violence…

  16. Research and development program for the development of advanced time-temperature dependent constitutive relationships. Volume 2: Programming manual

    Science.gov (United States)

    Cassenti, B. N.

    1983-01-01

    The results of a 10-month research and development program for nonlinear structural modeling with advanced time-temperature constitutive relationships are presented. The implementation of the theory in the MARC nonlinear finite element code is discussed, and instructions for the computational application of the theory are provided.

  17. Predictors of successful completion of a halfway-house program for chemically-dependent women.

    Science.gov (United States)

    Huselid, R F; Self, E A; Gutierres, S E

    1991-01-01

    Female substance abusers' attributions about the stability and globality of positive and negative life events were used as predictors of successful completion of a halfway-house treatment program. Instead of the typical beneficial effects associated with a self-serving attributional style, subjects who attributed their own recent negative life events to global (wide influence on life) and stable (always present) causes were more likely to successfully complete the treatment program. Subjects who perceived the cause of their first substance abuse (whether alcohol or another drug of abuse) as global and likely to affect substance abuse in the future also were more successful in completing the program. Not surprisingly, subjects who indicated that the cause of their quitting substance abuse was likely to lead them to stay off their drug of abuse in the future were more successful in completing the program. Finally, the amount and helpfulness of social support provided by a subject's AA sponsor were both significantly correlated with program completion. These results are interpreted as consistent with the program's Alcoholics Anonymous philosophical orientation. PMID:1645496

  18. Grande Ronde Basin Chinook Salmon Captive Brood and Conventional Supplementation Programs, 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Carmichael, Richard W. (Oregon Department of Fish and Wildlife, La Grande, OR)

    2003-07-01

    Endangered Species Permit Number 1011 (formerly Permit No. 973) authorizes ODFW to take listed spring chinook salmon juveniles from Catherine Creek (CC), Lostine River (LR) and Grande Ronde River (GR) for research and enhancement purposes. Modification 2 of this permit authorizes ODFW to take adults for spawning and the production and release of smolts for the Captive and Conventional broodstock programs. This report satisfies the requirement that an annual report be submitted. Herein we report on activities conducted and provide cursory data analyses for the Grande Ronde spring chinook salmon Captive and Conventional broodstock projects from 1 January-31 December 2002. The Grande Ronde Basin Spring Chinook Salmon Captive Broodstock Project is designed to rapidly increase numbers of salmon in stocks that are in imminent danger of extirpation. Parr are captured in Catherine Creek, upper Grande Ronde River and Lostine River and reared to adulthood in captivity. Upon maturation, they are spawned (within stocks) and their progeny reared to smoltification before being released into the natal stream of their parents. This program is co-managed by ODFW, National Marine Fisheries Service, the Nez Perce Tribe and Confederated Tribes of the Umatilla Indian Reservation.

  19. Recent USNRC results and program plans for elevated temperature time dependent material behavior

    International Nuclear Information System (INIS)

    The SI program thus provides NRC with a consultant capability to monitor the materials and structures efforts of applicants. Also, analytical and experimental work is actively pursued in areas with limited background or limited experimental basis. One major area, the extrapolation of test data from time limited tests to the full 40 year plant lifetime, has been chosen for a significant independent effort. This extrapolation study provides a focus for all creep-fatigue, fracture mode and analysis methods development to be done within the program. The supporting assurance which may be provided by sound in-service-inspection techniques must also be developed to the fullest possible extent. (author)

  20. Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis

    Czech Academy of Sciences Publication Activity Database

    Ondroušková, E.; Souček, Karel; Horváth, Viktor; Šmarda, J.

    2008-01-01

    Roč. 32, č. 4 (2008), s. 599-609. ISSN 0145-2126 R&D Projects: GA ČR(CZ) GA204/07/0834 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : apoptosis * autophagy * programmed cell death Subject RIV: BO - Biophysics Impact factor: 2.390, year: 2008

  1. Dependent Youth in Juvenile Justice: Do Positive Peer Culture Programs Work for Victims of Child Maltreatment?

    Science.gov (United States)

    Ryan, Joseph P.

    2006-01-01

    Objective: The purpose of this study is to identify and determine the individual and group-level factors associated with recidivism for children in a long-term Positive Peer Culture (PPC) program. The current study focuses specific attention on the role of child maltreatment in understanding the risk of recidivism. It is widely accepted that…

  2. Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

    OpenAIRE

    Adler, Carolyn E.; Seidel, Chris W.; McKinney, Sean A.; Sánchez Alvarado, Alejandro

    2014-01-01

    eLife digest Some animals can regrow whole limbs or organs after amputation. Flatworms called planaria, for example, can regenerate their whole body from small pieces. This remarkable ability depends on neoblasts—a type of stem cell found in planaria that can detect damaged or lost organs, migrate to the site of damage, produce the required cells, and integrate into the remaining tissues. Researchers hope that studying these animals will reveal ways to use stem cells to regenerate injured lim...

  3. Comorbid psychiatric diagnoses among individuals presenting to an addiction treatment program for alcohol dependence.

    LENUS (Irish Health Repository)

    Lyne, John Paul

    2011-01-01

    A retrospective patient record review was conducted to examine comorbid psychiatric diagnoses, and comorbid substance use, among 465 patients below 45 years of age, presenting to a national alcohol addiction treatment unit in Dublin, between 1995 and 2006. Rates were high for depressive disorder (25.3%) particularly among females (35.4%). Lifetime reported use of substances other than alcohol was 39.2%, and further analysis showed significantly higher rates of deliberate self-harm among this group. Lifetime reported use of ecstasy was also significantly associated with depression in this alcohol-dependent population using logistic regression analysis. Implications and limitations of the findings are discussed.

  4. Psychopathology and treatment outcome of drug dependent women in a perinatal program

    OpenAIRE

    Ingersoll, Karen S.; Knisely, Janet S.; Dawson, Kathryn S.; Schnoll, Sidney H.

    2004-01-01

    One hundred and five drug-dependent women in outpatient perinatal addiction treatment were classified by cluster analysis of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) profiles into high and low psychopathology (HP and LP) groups that differed on three validation measures. The HP group (n = 29, 27.6%) had elevations on MMPI-2 Scales F, 2, 4, 6, 7, and 8, while the LP group (n = 76, 72.4%) generated a normal range profile with elevations on Scales F and 4. Psychological outcome...

  5. Application of object-oriented programming in a time-dependent density-functional theory calculation of exciton binding energies

    CERN Document Server

    Yang, Zeng-hui

    2013-01-01

    This paper discusses the benefits of object-oriented programming to scientific computing, using our recent calculations of exciton binding energies with time-dependent density-functional theory (arXiv: 1302.6972) as a case study. We find that an object-oriented approach greatly facilitates the development, the debugging, and the future extension of the code by promoting code reusing. We show that parallelism is added easily in our code in a object-oriented fashion with ScaLAPACK, Boost::MPI and OpenMP.

  6. Prenatal immune programming of the sex-dependent risk for major depression.

    Science.gov (United States)

    Gilman, S E; Cherkerzian, S; Buka, S L; Hahn, J; Hornig, M; Goldstein, J M

    2016-01-01

    Maternal immune functioning during pregnancy contributes to sex-dependent deficits in neurodevelopment and to behaviors associated with affective traits in preclinical studies, and has been indirectly associated with offspring depression in epidemiologic studies. We therefore investigated the association between immune activity during pregnancy and the risk of depression among male and female offspring. We conducted a case-control study of depression (n=484 cases and n=774 controls) using data from the New England Family Study, a pregnancy cohort enrolled between 1959 and 1966 that assessed psychiatric outcomes in adult offspring (mean age=39.7 years). We assayed concentrations of three pro-inflammatory cytokines, interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α, and the anti-inflammatory cytokine, IL-10, in maternal serum collected at the end of the second and beginning of the third trimesters. High maternal TNF-α was associated with reduced odds of depression among both male and female offspring (odds ratio (OR)=0.68; confidence interval (CI)=0.48, 0.98). However, when considering the TNF-α to IL-10 ratio, a measure of the ratio of pro- to anti-inflammatory loading, maternal immune effects on offspring depression differed significantly by sex (χ(2)=13.9, degrees of freedom=4, P=0.008). Among females, higher maternal TNF-α:IL-10 was associated with reduced odds of depression (OR=0.51; CI=0.32, 0.81), whereas, among males, high maternal TNF-α:IL-10 was associated with elevated odds of depression (OR=1.86; CI=1.02, 3.39). Thus, the balance between TNF-α and IL-10 in maternal prenatal serum was associated with depression in a sex-dependent manner. These findings are consistent with the role of TNF-α in the maturation of the sexually dimorphic fetal brain circuitry that regulates stress and affective responses, and support a prenatal stress-immune model of depression pathogenesis. PMID:27244231

  7. 南海区驯养条石鲷亲鱼的初次性成熟和产卵%First maturation and spawning of cultured Oplegnathus fasciatus broodstock in the South China Sea

    Institute of Scientific and Technical Information of China (English)

    区又君; 李加儿; 林锋

    2014-01-01

    2008年4月初在广东省饶平县对2006年5月人工孵化和培育的2龄条石鲷( Oplegnathus fasciatus)成熟亲鱼进行激素诱导,研究和观察条石鲷亲鱼初次性成熟的繁殖生物学。结果显示,在南海区全人工养殖的条石鲷亲鱼初次性成熟年龄为2龄,成熟亲鱼的最小型为全长245 mm、体质量610 g,最大个体为全长300 mm、体质量1450 g;产卵季节为4月10日~7月15日,产卵盛期为4月中旬至6月下旬;为升温产卵型鱼类,产卵温度为20.0~28.8℃,适宜的产卵温度为20.7~27.6℃;雌、雄亲鱼发育同步,个体大小和成熟年龄差别不大;雌鱼属于一年一次分批产卵类型,产卵期超过3个月;24尾初次性成熟雌性亲鱼的总产卵量为3180.0×104粒,日最高产卵量为341.5×104粒;其产卵量和受精卵质量与水温的变化关系密切,受精卵的浮卵率随温度的变化而变化,在水温相对衡定时,浮卵率相对稳定并维持在80%~95%的较高水平;受精卵平均卵径为(0.860±0.023)mm,油球径为(0.191±0.009)mm。%In early April of 2008,we carried out hormone inducement in 2-year-old Oplegnathus fasciatus broodstocks hatched in May of 2006 in Raoping of Guangdong Province,so as to investgate their reproductive biology for first maturation. Results show that in the South China Sea,it took 2 years for the first maturation with biological minimum size of 245 mm in total length and 610 g in weight, maximum size being 300 mm and 1 450 g for the O. fasciatus broodstocks by complete artificial breeding. Spawning season was from A-pril 10 to July 15 with the peak period from middle April to late June. Being a thermo-dependent spawning type,the breeding tempera-ture of the fish ranged from 20. 0~28. 8 ℃ with suitable temperature of 20. 7~27. 6 ℃. Development was synchronous for both sexes and no significant difference was found in size and mature age. Being an annual spawning multiplicity

  8. VNAP2: a computer program for computation of two-dimensional, time-dependent, compressible, turbulent flow

    Energy Technology Data Exchange (ETDEWEB)

    Cline, M.C.

    1981-08-01

    VNAP2 is a computer program for calculating turbulent (as well as laminar and inviscid), steady, and unsteady flow. VNAP2 solves the two-dimensional, time-dependent, compressible Navier-Stokes equations. The turbulence is modeled with either an algebraic mixing-length model, a one-equation model, or the Jones-Launder two-equation model. The geometry may be a single- or a dual-flowing stream. The interior grid points are computed using the unsplit MacCormack scheme. Two options to speed up the calculations for high Reynolds number flows are included. The boundary grid points are computed using a reference-plane-characteristic scheme with the viscous terms treated as source functions. An explicit artificial viscosity is included for shock computations. The fluid is assumed to be a perfect gas. The flow boundaries may be arbitrary curved solid walls, inflow/outflow boundaries, or free-jet envelopes. Typical problems that can be solved concern nozzles, inlets, jet-powered afterbodies, airfoils, and free-jet expansions. The accuracy and efficiency of the program are shown by calculations of several inviscid and turbulent flows. The program and its use are described completely, and six sample cases and a code listing are included.

  9. Revised Master Plan for the Hood River Production Program, Technical Report 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Oregon Department of Fish and Wildlife; Confederated Tribes of the Warm Springs Reservation

    2008-04-28

    The Hood River Production Program (HRPP) is a Bonneville Power Administration (BPA) funded program initiated as a mitigation measure for Columbia River hydrosystem effects on anadromous fish. The HRPP began in the early 1990s with the release of spring Chinook and winter steelhead smolts into the basin. Prior to implementation, co-managers, including the Confederated Tribes of the Warm Springs Reservation and the Oregon Department of Fish and Wildlife drafted the Hood River Production Master Plan (O'Toole and ODFW 1991a; O'Toole and ODFW 1991b) and the Pelton Ladder Master Plan (Smith and CTWSR 1991). Both documents were completed in 1991 and subsequently approved by the Council in 1992 and authorized through a BPA-led Environmental Impact Statement in 1996. In 2003, a 10-year programmatic review was conducted for BPA-funded programs in the Hood River (Underwood et al. 2003). The primary objective of the HRPP Review (Review) was to determine if program goals were being met, and if modifications to program activities would be necessary in order to meet or revise program goals. In 2003, an agreement was signed between PacifiCorp and resource managers to remove the Powerdale Dam (RM 10) and associated adult trapping facility by 2010. The HRPP program has been dependant on the adult trap to collect broodstock for the hatchery programs; therefore, upon the dam's removal, some sort of replacement for the trap would be needed to continue the HRPP. At the same time the Hood River Subbasin Plan (Coccoli 2004) was being written and prompted the co-managers to considered future direction of the program. This included revising the numerical adult fish objectives based on the assimilated data and output from several models run on the Hood River system. In response to the Review as well as the Subbasin Plan, and intensive monitoring and evaluation of the current program, the HRPP co-managers determined the spring Chinook program was not achieving the HRPP

  10. Evaluation of Jump into Action: A Program to Reduce the Risk of Non-Insulin Dependent Diabetes Mellitus in School Children on the Texas-Mexico Border.

    Science.gov (United States)

    Holcomb, J. David; Lira, Juanita; Kingery, Paul M.; Smith, D. W.; Lane, Dorothy; Goodway, Jackie

    1998-01-01

    Evaluated Jump into Action, a non-insulin dependent diabetes mellitus (NIDDM)-prevention program that encouraged students to eat well and exercise regularly to reduce NIDDM risks. Surveys of predominantly Hispanic fifth graders and their teachers at Texas-Mexico border schools indicated that the program increased NIDDM-prevention knowledge and…

  11. Modality-dependent dose requirements in the Austrian breast cancer early detection program. First results from technical quality assurance

    International Nuclear Information System (INIS)

    The Austrian Breast Cancer Early Detection Program (BKFP) has officially started in January 2014. In order to ensure that all participating women can rely on a sufficient cancer detection rate while at the same time the required dose is as low as reasonably achievable, all participating radiology institutes (approx. 200) have to fulfill strict quality assurance requirements. The control and certification is performed by the Reference Center for Technical Quality Assurance (RefZQS), which has been developing the methods and tolerances in a pilot project since 2007. The limits are defined in the EUREF-Oeprotocol which is based on the European EPQC guidelines. From the requirement for optimized image quality while simultaneously following the ALARA principle, we found modality-dependent dose requirements, which we had expected but which have now been compiled for the first time for Austria.

  12. SGOTL: A Computer Program for Modeling High-Resolution, Height-Dependent Gravity Effect of Ocean Tide Loading

    Directory of Open Access Journals (Sweden)

    Cheinway Hwang and Jiu-Fu Huang

    2012-01-01

    Full Text Available SGOTL, a computer package coded in FORTRAN, has been developed to model the gravity effect due to ocean tide loading (OTL, especially for a coastal station with large ocean tides. SGOTL uses a regional and a global tide model to account separately for near (inner and far (outer zone contributions, and optimizes an inner-zone region and grid interval for numerical convolution. Height dependent _ functions for Newtonian and elastic effects are developed. The coastline is defined by the full-resolution GMT shoreline, and optionally a digital elevation model (DEM. A case study using gravity observations at the Hsinchu superconducting gravity station and some offshore islands around the Taiwan Strait suggests that SGOTL outperforms some selected global OTL programs and achieves an accuracy of 0.1 μGal for 8 leading tidal constituents.

  13. Development of numerical modelling of analysis program for energy-dissipating behaviour of velocity dependent hydraulic damper

    Indian Academy of Sciences (India)

    M-H Shih; W-P Sung; M-J Wu

    2010-10-01

    A relief valve parallel to the throttle valve is added to a Velocity dependent hydraulic damper (VDHD) so that the orifice size that regulates the oil flow can be adjusted. This device adjustment will allow the damper to have an adaptive control of damping by changing its damping coefficient. A mathematical model including a serial friction model and a small damper that is parallel to the friction model added to the Maxwell model for simulating the actual energy-dissipating behaviour of the VDHD was proposed in this research. To extend the useful value of VDHD, a numerical analysis model based on the SAP2000 nonlinear analysis program was applied to simulate the energy-dissipating characteristics of VDHD in this study. The analysis results obtained by using the mathematical model and the proposed SAP2000 numerical model conform to the seismic resistant test results, and confirm that the SAP2000 nonlinear analysis program can accurately describe the actual energy-dissipating behaviour of the VDHD installed on structures under various energy-dissipating situations.

  14. Ursodeoxycholic acid suppresses mitochondria-dependent programmed cell death induced by sodium nitroprusside in SH-SY5Y cells

    International Nuclear Information System (INIS)

    Although ursodeoxycholic acid (UDCA) and its highly water-soluble formula (Yoo's solution; YS) have been shown to prevent neuronal damage, the effects of UDCA or YS against Parkinson's disease (PD)-related dopaminergic cell death has not been studied. This study investigated the protective effects of UDCA and YS on sodium nitroprusside (SNP)-induced cytotoxicity in human dopaminergic SH-SY5Y cells. Both UDCA (50–200 μM) and YS (100–200 μM) dose-dependently prevented SNP (1 mM)-induced cell death. Results showed that both UDCA and YS effectively attenuated the production of total reactive oxygen species (ROS), peroxynitrite (ONOO−) and nitric oxide (NO), and markedly inhibited the mitochondrial membrane potential (MMP) loss and intracellular reduced glutathione (GSH) depletion. SNP-induced programmed cell death events, such as nuclear fragmentation, caspase-3/7 and -9 activation, Bcl-2/Bax ratio decrease, and cytochrome c release, were significantly attenuated by both UDCA and YS. Furthermore, selective inhibitor of phosphatidylinositiol-3-kinase (PI3K), LY294002, and Akt/PKB inhibitor, triciribine, reversed the preventive effects of UDCA on the SNP-induced cytotoxicity and Bax translocation. These results suggest that UDCA can protect SH-SY5Y cells under programmed cell death process by regulating PI3K-Akt/PKB pathways.

  15. FORTRAN 77 programs for conductive cooling of dikes with temperature-dependent thermal properties and heat of crystallization

    Science.gov (United States)

    Delaney, P.T.

    1988-01-01

    Temperature histories obtained from transient heat-conduction theory are applicable to most dikes despite potential complicating effects related to magma flow during emplacement, groundwater circulation, and metamorphic reaction during cooling. Here. machine-independent FORTRAN 77 programs are presented to calculate temperatures in and around dikes as they cool conductively. Analytical solutions can treat thermal-property contrasts between the dike and host rocks, but cannot address the release of magmatic heat of crystallization after the early stages of cooling or the appreciable temperature dependence of thermal conductivity and diffusivity displayed by most rock types. Numerical solutions can incorporate these additional factors. The heat of crystallization can raise the initial temperature at the dike contact, ??c1, about 100??C above that which would be estimated if it were neglected, and can decrease the rate at which the front of solidified magma moves to the dike center by a factor of as much as three. Thermal conductivity and diffusivity of rocks increase with decreasing temperature and, at low temperatures, these properties increase more if the rocks are saturated with water. Models that treat these temperature dependencies yield estimates of ??c1 that are as much as 75??C beneath those which would be predicted if they were neglected. ?? 1988.

  16. Multidendritic sensory neurons in the adult Drosophila abdomen: origins, dendritic morphology, and segment- and age-dependent programmed cell death

    Directory of Open Access Journals (Sweden)

    Sugimura Kaoru

    2009-10-01

    Full Text Available Abstract Background For the establishment of functional neural circuits that support a wide range of animal behaviors, initial circuits formed in early development have to be reorganized. One way to achieve this is local remodeling of the circuitry hardwiring. To genetically investigate the underlying mechanisms of this remodeling, one model system employs a major group of Drosophila multidendritic sensory neurons - the dendritic arborization (da neurons - which exhibit dramatic dendritic pruning and subsequent growth during metamorphosis. The 15 da neurons are identified in each larval abdominal hemisegment and are classified into four categories - classes I to IV - in order of increasing size of their receptive fields and/or arbor complexity at the mature larval stage. Our knowledge regarding the anatomy and developmental basis of adult da neurons is still fragmentary. Results We identified multidendritic neurons in the adult Drosophila abdomen, visualized the dendritic arbors of the individual neurons, and traced the origins of those cells back to the larval stage. There were six da neurons in abdominal hemisegment 3 or 4 (A3/4 of the pharate adult and the adult just after eclosion, five of which were persistent larval da neurons. We quantitatively analyzed dendritic arbors of three of the six adult neurons and examined expression in the pharate adult of key transcription factors that result in the larval class-selective dendritic morphologies. The 'baseline design' of A3/4 in the adult was further modified in a segment-dependent and age-dependent manner. One of our notable findings is that a larval class I neuron, ddaE, completed dendritic remodeling in A2 to A4 and then underwent caspase-dependent cell death within 1 week after eclosion, while homologous neurons in A5 and in more posterior segments degenerated at pupal stages. Another finding is that the dendritic arbor of a class IV neuron, v'ada, was immediately reshaped during post

  17. Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System

    Directory of Open Access Journals (Sweden)

    José Fernando Maya-Vetencourt

    2013-01-01

    Full Text Available The capability of the brain to change functionally in response to sensory experience is most active during early stages of development but it decreases later in life when major alterations of neuronal network structures no longer take place in response to experience. This view has been recently challenged by experimental strategies based on the enhancement of environmental stimulation levels, genetic manipulations, and pharmacological treatments, which all have demonstrated that the adult brain retains a degree of plasticity that allows for a rewiring of neuronal circuitries over the entire life course. A hot spot in the field of neuronal plasticity centres on gene programs that underlie plastic phenomena in adulthood. Here, I discuss the role of the recently discovered neuronal-specific and activity-dependent transcription factor NPAS4 as a critical mediator of plasticity in the nervous system. A better understanding of how modifications in the connectivity of neuronal networks occur may shed light on the treatment of pathological conditions such as brain damage or disease in adult life, some of which were once considered untreatable.

  18. Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

    OpenAIRE

    Flavell, Steven W; Kim, Tae-Kyung; Gray, Jesse M.; Harmin, David A.; Hemberg, Martin; Hong, Elizabeth J.; Markenscoff-Papadimitriou, Eirene; Bear, Daniel M.; Greenberg, Michael E.

    2008-01-01

    Although many transcription factors are known to control important aspects of neural development, the genome-wide programs that are directly regulated by these factors are not known. We have characterized the genetic program that is activated by MEF2, a key regulator of activity-dependent synapse development. These MEF2 target genes have diverse functions at synapses, revealing a broad role for MEF2 in synapse development. Several of the MEF2 targets are mutated in human neurological disorder...

  19. Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection

    OpenAIRE

    Flavell, Steven W; Kim, Tae-Kyung; Gray, Jesse M.; Harmin, David A.; Hemberg, Martin; Hong, Elizabeth J.; Markenscoff-Papadimitriou, Eirene; Bear, Daniel M.; Greenberg, Michael E.

    2008-01-01

    Although many transcription factors are known to control important aspects of neural development, the genome-wide programs that are directly regulated by these factors are not known. We have characterized the genetic program that is activated by MEF2, a key regulator of activity-dependent synapse development. These MEF2 target genes have diverse functions at synapses, revealing a broad role for MEF2 in synapse development. Several of the MEF2 targets are mutated in human neurological disorder...

  20. The Effects of Visual Cues and Learners' Field Dependence in Multiple External Representations Environment for Novice Program Comprehension

    Science.gov (United States)

    Wei, Liew Tze; Sazilah, Salam

    2012-01-01

    This study investigated the effects of visual cues in multiple external representations (MER) environment on the learning performance of novices' program comprehension. Program codes and flowchart diagrams were used as dual representations in multimedia environment to deliver lessons on C-Programming. 17 field independent participants and 16 field…

  1. WAVE: a computer program for one-dimensional stress wave analysis in a time-dependent inelastic rock using a generalized Voigt model

    Energy Technology Data Exchange (ETDEWEB)

    Sawyer, S.G.

    1972-01-01

    A Fortran IV computer program entitled WAVE, which employs an explicit finite difference scheme for solving the one-dimensional wave equation for a time-dependent inelastic rock has been developed. The viscoelastic properties of the rock are represented in terms of a generalized Voigt model. The theory on which the computer program is based is rederived and a short description of the program is given. The computer program input instructions, a listing of the computer program, and example problems with required input and subsequent printed output are presented in appendixes. In the example problems, calculated results are free of spurious oscillations which occur in certain other methods of numerical calculation, notably the extended Ritz method.

  2. Grande Ronde Endemic Spring Chinook Salmon Supplementation Program; Satellite Facilities Operation and Maintenance, 2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McLean, Michael L.; Seeger, Ryan; Hewitt, Laurie (Confederated Tribes of the Umatilla Indian Reservation, Department of Natural Resources, Pendleton, OR)

    2006-01-01

    There were 2 acclimation periods at the Catherine Creek Acclimation Facility (CCAF) in 2005. During the early acclimation period, 130,748 smolts were delivered from Lookingglass Hatchery (LGH) on 7 March. This group contained progeny of both the captive (53%) and conventional broodstock programs. The size of the fish at delivery was 23.9 fish/lb. Volitional releases began 14 March 2005 and ended 27 March with an estimated total (based on PIT tag detections of 3,187) of 29,402 fish leaving the raceways. This was 22.5% of the total fish delivered. Fish remaining in the raceways after volitional release were forced out. Hourly detections of PIT-tagged fish showed that most of the fish left around 1900 hours. The size of the fish just before the volitional release was 23.9 and the size of the fish remaining just before the forced release was 23.2 fish/lb. The total mortality for the acclimation period was 204 (0.16%). The total number of fish released from the acclimation facility during the early period was 130,544. During the second acclimation period 59,100 smolts were delivered from LGH on 28 March. This group was comprised entirely of progeny from the conventional broodstock program. The size of the fish at delivery was 21.8 fish/lb. Volitional releases began 3 April 2005 and ended with a force out emergency release on 7 April. The size of the fish just before the volitional release was 21.8. The total mortality for the acclimation period was 64 (0.11 %). The total number of fish released from the acclimation facility during the late period was 59,036. There was only 1 planned acclimation period at the Upper Grande Ronde Acclimation Facility (UGRAF) in 2005. During the early acclimation period 105,418 smolts were delivered from LGH on 8 March. This group was comprised entirely of progeny from the conventional broodstock program. The size of the fish at delivery was 21.0 fish/lb. There was no volitional release in 2005 due to freezing air and water conditions

  3. Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes.

    Directory of Open Access Journals (Sweden)

    Alok Das Mohapatra

    2011-09-01

    Full Text Available BACKGROUND: Successful embryogenesis is a critical rate limiting step for the survival and transmission of parasitic worms as well as pathology mediated by them. Hence, blockage of this important process through therapeutic induction of apoptosis in their embryonic stages offers promise for developing effective anti-parasitic measures against these extra cellular parasites. However, unlike in the case of protozoan parasites, induction of apoptosis as a therapeutic approach is yet to be explored against metazoan helminth parasites. METHODOLOGY/PRINCIPAL FINDINGS: For the first time, here we developed and evaluated flow cytometry based assays to assess several conserved features of apoptosis in developing embryos of a pathogenic filarial nematode Setaria digitata, in-vitro as well as ex-vivo. We validated programmed cell death in developing embryos by using immuno-fluorescence microscopy and scoring expression profile of nematode specific proteins related to apoptosis [e.g. CED-3, CED-4 and CED-9]. Mechanistically, apoptotic death of embryonic stages was found to be a caspase dependent phenomenon mediated primarily through induction of intracellular ROS. The apoptogenicity of some pharmacological compounds viz. DEC, Chloroquine, Primaquine and Curcumin were also evaluated. Curcumin was found to be the most effective pharmacological agent followed by Primaquine while Chloroquine displayed minimal effect and DEC had no demonstrable effect. Further, demonstration of induction of apoptosis in embryonic stages by lipid peroxidation products [molecules commonly associated with inflammatory responses in filarial disease] and demonstration of in-situ apoptosis of developing embryos in adult parasites in a natural bovine model of filariasis have offered a framework to understand anti-fecundity host immunity operational against parasitic helminths. CONCLUSIONS/SIGNIFICANCE: Our observations have revealed for the first time, that induction of apoptosis in

  4. Levedura como pronutriente em dietas para matrizes e alevinos de tilápia-do-nilo Yeast as pro-nutrient in diets for Nile tilapia broodstock females and fingerlings

    Directory of Open Access Journals (Sweden)

    João Fernando Albers Koch

    2011-11-01

    Full Text Available Objetivou-se avaliar a levedura Saccharomyces cerevisiae como pronutriente em dietas para matrizes e alevinos de tilápia-do-nilo. O experimento foi realizado em duas etapas na UNESP. Dois grupos de fêmeas reprodutoras de tilápia (734,47 ± 202,08 g, variedade GIFT, foram arraçoados por 100 dias com rações isoproteicas (34% PD e isoenergéticas (3.400 kcal ED/kg, uma contendo 2% de levedura íntegra e outra sem levedura. As fêmeas foram fecundadas naturalmente e as larvas, ao final da absorção do saco vitelino, foram alocadas em aquários de 3,5 L e alimentadas por 30 dias com três rações isoproteicas (35% PD e isoenergéticas (3.280 kcal ED/kg: sem levedura; contendo 1% de levedura íntegra; ou contendo 1% de levedura autolisada. Após o abate, foram calculadas as seguintes variáveis de desempenho produtivo: biomassa final; ganho de peso; consumo de ração; conversão alimentar aparente; peso final; comprimento total; fator de condição corporal; altura média; e sobrevivência. Foram analisados ainda os teores de matéria seca, matéria mineral, proteína bruta e extrato etéreo da carcaça dos animais. Verificou-se interação significativa dos fatores analisados para todas as variáveis de desempenho produtivo, exceto para o consumo de ração. O fornecimento de levedura íntegra (2,0% em dietas para matrizes ou alevinos de tilápia-do-nilo (1,0% aumenta a taxa de sobrevivência dos alevinos.This trial was conducted to evaluate dietary yeast Saccharomyces cerevisiae as pro-nutrient for diets for Nile tilapia broodstock females and fingerlings. The trial was conducted in two phases at UNESP. Two groups of tilapia broodstock females (734.47 ± 202.08 g, GIFT genealogy, were fed with isoprotein (34% DP and isoenergy (3400 kcal DE/kg diets for 100 days, one with 2% autolized yeast and the other with no yeast. Broodstock females were naturally fecundated, and larvae, at the end of yolk sac absorption, were stocked into 3.5-L

  5. Engagement and Substance Dependence in a Primary Care-Based Addiction Treatment Program for People Infected with HIV and People at High-Risk for HIV Infection.

    Science.gov (United States)

    Walley, Alexander Y; Palmisano, Joseph; Sorensen-Alawad, Amy; Chaisson, Christine; Raj, Anita; Samet, Jeffrey H; Drainoni, Mari-Lynn

    2015-12-01

    To improve outcomes for people with substance dependence and HIV infection or at risk for HIV infection, patients were enrolled in a primary care-based addiction treatment program from 2008-2012 that included a comprehensive substance use assessment, individual and group counseling, addiction pharmacotherapy and case management. We examined whether predisposing characteristics (depression, housing status, polysubstance use) and an enabling resource (buprenorphine treatment) were associated with engagement in the program and persistent substance dependence at 6 months. At program enrollment 61% were HIV-infected, 53% reported heroin use, 46% reported alcohol use, 37% reported cocaine use, and 28% reported marijuana use in the past 30 days, 72% reported depression, 19% were homeless, and 53% had polysubstance use. Within 6-months 60% had been treated with buprenorphine. Engagement (defined as 2 visits in first 14 days and 2 additional visits in next 30 days) occurred in 64%; 49% had substance dependence at 6-months. Receipt of buprenorphine treatment was associated with engagement (Adjusted Odds Ratio (AOR) 8.32 95% CI: 4.13-16.77). Self-reported depression at baseline was associated with substance dependence at 6-months (AOR 3.30 95% CI: 1.65-6.61). Neither housing status nor polysubstance use was associated with engagement or substance dependence. The FAST PATH program successfully engaged and treated patients in a primary care-based addiction treatment program. Buprenorphine, a partial opioid agonist, was a major driver of addiction treatment engagement. Given depression's association with adverse outcomes in this clinical population, including mental health treatment as part of integrated care holds potential to improve addiction treatment outcomes. PMID:26298399

  6. Research and development program for non-linear structural modeling with advanced time-temperature dependent constitutive relationships

    Science.gov (United States)

    Walker, K. P.

    1981-01-01

    Results of a 20-month research and development program for nonlinear structural modeling with advanced time-temperature constitutive relationships are reported. The program included: (1) the evaluation of a number of viscoplastic constitutive models in the published literature; (2) incorporation of three of the most appropriate constitutive models into the MARC nonlinear finite element program; (3) calibration of the three constitutive models against experimental data using Hastelloy-X material; and (4) application of the most appropriate constitutive model to a three dimensional finite element analysis of a cylindrical combustor liner louver test specimen to establish the capability of the viscoplastic model to predict component structural response.

  7. Programming

    International Nuclear Information System (INIS)

    The programmer's task is often taken to be the construction of algorithms, expressed in hierarchical structures of procedures: this view underlies the majority of traditional programming languages, such as Fortran. A different view is appropriate to a wide class of problem, perhaps including some problems in High Energy Physics. The programmer's task is regarded as having three main stages: first, an explicit model is constructed of the reality with which the program is concerned; second, this model is elaborated to produce the required program outputs; third, the resulting program is transformed to run efficiently in the execution environment. The first two stages deal in network structures of sequential processes; only the third is concerned with procedure hierarchies. (orig.)

  8. 海水鱼类亲体必需脂肪酸营养的研究进展%Research progress of essential fatty acids nutrition in marine fish broodstock

    Institute of Scientific and Technical Information of China (English)

    彭士明; 李云莉; 施兆鸿; 高权新; 张晨捷; 王建钢

    2016-01-01

    Fatty acids,especially essential fatty acids,play an important role in the regulation of reproductive performance in marine fish.The importance of long-chain polyunsaturated fatty acids (LC-PUFA),especially 22:6n-3 (DHA),20:5n-3 (EPA)and 20:4n-6 (ARA),in broodstock nutrition has attracted attention in the last two decades.It has been well documented that dietary essential fatty acid is a nutritional factor that greatly affects spawning performance,egg and larval quality of fish.Lipids are utilized as energy sources throughout embryogenesis,and particularly in the later stages of development prior to hatching.EPA and DHA are the major fatty acids in the total lipid of eggs of most fish and these fatty acids markedly influence the reproductive parameters.DHA,especially abundant in retina and brain,has a particularly important role in maintaining the structure and function of the cell membranes of these tissues.In addition,as a major fatty acid in phosphatidylinositol and precursor of prostaglandin, ARA stimulates ovarian and testicular steroidogenesis and is assumed to be involved in embryonic development of the immune system,hatching and early larval performance.Reported studies on essential fatty acids in marine fish broodstock mainly cover four fields:(1 )Requirements.Fat provides energy and essential fatty acids for the growth of marine fishes and play critical roles in marine fish nutrition.n-3 LC-PUFA are essential fatty acids.It is typically recognized that marine fishes have a limited ability to convert shorter chain and less unsaturated fatty acids into n-3 LC-PUFA.Therefore,adequate amounts of n-3 LC-PUFA must be supplied through the diet to ensure normal growth and development.Studies on some marine fish species have shown that different fishes require different levels of n-3 LC-PUFA,and also extremely high or low levels of dietary n-3 LC-PUFA are not conducive to the normal growth and development.Hence,the provision of appropriate amounts of dietary n-3

  9. Research progress of essential fatty acids nutrition in marine fish broodstock%海水鱼类亲体必需脂肪酸营养的研究进展

    Institute of Scientific and Technical Information of China (English)

    彭士明; 李云莉; 施兆鸿; 高权新; 张晨捷; 王建钢

    2016-01-01

    Fatty acids,especially essential fatty acids,play an important role in the regulation of reproductive performance in marine fish.The importance of long-chain polyunsaturated fatty acids (LC-PUFA),especially 22:6n-3 (DHA),20:5n-3 (EPA)and 20:4n-6 (ARA),in broodstock nutrition has attracted attention in the last two decades.It has been well documented that dietary essential fatty acid is a nutritional factor that greatly affects spawning performance,egg and larval quality of fish.Lipids are utilized as energy sources throughout embryogenesis,and particularly in the later stages of development prior to hatching.EPA and DHA are the major fatty acids in the total lipid of eggs of most fish and these fatty acids markedly influence the reproductive parameters.DHA,especially abundant in retina and brain,has a particularly important role in maintaining the structure and function of the cell membranes of these tissues.In addition,as a major fatty acid in phosphatidylinositol and precursor of prostaglandin, ARA stimulates ovarian and testicular steroidogenesis and is assumed to be involved in embryonic development of the immune system,hatching and early larval performance.Reported studies on essential fatty acids in marine fish broodstock mainly cover four fields:(1 )Requirements.Fat provides energy and essential fatty acids for the growth of marine fishes and play critical roles in marine fish nutrition.n-3 LC-PUFA are essential fatty acids.It is typically recognized that marine fishes have a limited ability to convert shorter chain and less unsaturated fatty acids into n-3 LC-PUFA.Therefore,adequate amounts of n-3 LC-PUFA must be supplied through the diet to ensure normal growth and development.Studies on some marine fish species have shown that different fishes require different levels of n-3 LC-PUFA,and also extremely high or low levels of dietary n-3 LC-PUFA are not conducive to the normal growth and development.Hence,the provision of appropriate amounts of dietary n-3

  10. Integrating nutrition support for food-insecure patients and their dependents into an HIV care and treatment program in Western Kenya.

    Science.gov (United States)

    Mamlin, Joseph; Kimaiyo, Sylvester; Lewis, Stephen; Tadayo, Hannah; Jerop, Fanice Komen; Gichunge, Catherine; Petersen, Tomeka; Yih, Yuehwern; Braitstein, Paula; Einterz, Robert

    2009-02-01

    The Academic Model Providing Access to Healthcare (AMPATH) is a partnership between Moi Teaching and Referral Hospital, Moi University School of Medicine, and a consortium of universities led by Indiana University. AMPATH has over 50,000 patients in active care in 17 main clinics around western Kenya. Despite antiretroviral therapy, many patients were not recovering their health because of food insecurity. AMPATH therefore established partnerships with the World Food Program and United States Agency for International Development and began high-production farms to complement food support. Today, nutritionists assess all AMPATH patients and dependents for food security and refer those in need to the food program. We describe the implementation, challenges, and successes of this program. PMID:19059851

  11. The Impact of Age Pension Eligibility Age on Retirement and Program Dependence: Evidence from an Australian Experiment

    OpenAIRE

    Kadir Atalay; Garry F Barrett

    2012-01-01

    Identifying the effect of the financial incentives created by social security systems on the retirement behaviour of individuals requires exogenous variation in program parameters. In this paper we study the 1993 Australian Age Pension reform which increased the eligibility age for women to access the social security benefit. We find economically significant responses to the increase in the Age Pension eligibility age. An increase in the eligibility age of 1 year induced a decline in retireme...

  12. Is an "ideal" service institution image the same for all referral sources? The case of chemical dependency treatment programs.

    Science.gov (United States)

    Johnson, K; LaTour, M S

    1993-01-01

    In a competitive market like chemical dependency treatment, segmenting the professional referral market according to an "ideal" service image may offer a service institution a strategic advantage. Results of this study suggest that while different professionals in a referral market may attach differential importance to the same service feature, a favorable or unfavorable "image" seems to encompass how well both the professional and the professionals' client are treated by the service institution. PMID:10129241

  13. CD4+ type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes

    DEFF Research Database (Denmark)

    Kadri, Nadir; Korpos, Eva; Gupta, Shashank;

    2012-01-01

    exhibited a memory phenotype including high ICOS expression, increased cytokine production, and limited display of NK cell markers, compared with double-negative 24aß NKT cells. Blocking of ICOS or the programmed death-1/programmed death ligand 1 pathway was shown to abolish the regulation that occurred......Type 1 diabetes (T1D) is a chronic autoimmune disease that results from T cell-mediated destruction of pancreatic ß cells. CD1d-restricted NKT lymphocytes have the ability to regulate immunity, including autoimmunity. We previously demonstrated that CD1d-restricted type II NKT cells, which carry...... diverse TCRs, prevented T1D in the NOD mouse model for the human disease. In this study, we show that CD4(+) 24aß type II NKT cells, but not CD4/CD8 double-negative NKT cells, were sufficient to downregulate diabetogenic CD4(+) BDC2.5 NOD T cells in adoptive transfer experiments. CD4(+) 24aß NKT cells...

  14. Novel algorithm and MATLAB-based program for automated power law analysis of single particle, time-dependent mean-square displacement

    Science.gov (United States)

    Umansky, Moti; Weihs, Daphne

    2012-08-01

    In many physical and biophysical studies, single-particle tracking is utilized to reveal interactions, diffusion coefficients, active modes of driving motion, dynamic local structure, micromechanics, and microrheology. The basic analysis applied to those data is to determine the time-dependent mean-square displacement (MSD) of particle trajectories and perform time- and ensemble-averaging of similar motions. The motion of particles typically exhibits time-dependent power-law scaling, and only trajectories with qualitatively and quantitatively comparable MSD should be ensembled. Ensemble averaging trajectories that arise from different mechanisms, e.g., actively driven and diffusive, is incorrect and can result inaccurate correlations between structure, mechanics, and activity. We have developed an algorithm to automatically and accurately determine power-law scaling of experimentally measured single-particle MSD. Trajectories can then categorized and grouped according to user defined cutoffs of time, amplitudes, scaling exponent values, or combinations. Power-law fits are then provided for each trajectory alongside categorized groups of trajectories, histograms of power laws, and the ensemble-averaged MSD of each group. The codes are designed to be easily incorporated into existing user codes. We expect that this algorithm and program will be invaluable to anyone performing single-particle tracking, be it in physical or biophysical systems. Catalogue identifier: AEMD_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEMD_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 25 892 No. of bytes in distributed program, including test data, etc.: 5 572 780 Distribution format: tar.gz Programming language: MATLAB (MathWorks Inc.) version 7.11 (2010b) or higher, program

  15. Hybrid OpenMP/MPI programs for solving the time-dependent Gross-Pitaevskii equation in a fully anisotropic trap

    Science.gov (United States)

    Satarić, Bogdan; Slavnić, Vladimir; Belić, Aleksandar; Balaž, Antun; Muruganandam, Paulsamy; Adhikari, Sadhan K.

    2016-03-01

    We present hybrid OpenMP/MPI (Open Multi-Processing/Message Passing Interface) parallelized versions of earlier published C programs (Vudragović et al. 2012) for calculating both stationary and non-stationary solutions of the time-dependent Gross-Pitaevskii (GP) equation in three spatial dimensions. The GP equation describes the properties of dilute Bose-Einstein condensates at ultra-cold temperatures. Hybrid versions of programs use the same algorithms as the C ones, involving real- and imaginary-time propagation based on a split-step Crank-Nicolson method, but consider only a fully-anisotropic three-dimensional GP equation, where algorithmic complexity for large grid sizes necessitates parallelization in order to reduce execution time and/or memory requirements per node. Since distributed memory approach is required to address the latter, we combine MPI programming paradigm with existing OpenMP codes, thus creating fully flexible parallelism within a combined distributed/shared memory model, suitable for different modern computer architectures. The two presented C/OpenMP/MPI programs for real- and imaginary-time propagation are optimized and accompanied by a customizable makefile. We present typical scalability results for the provided OpenMP/MPI codes and demonstrate almost linear speedup until inter-process communication time starts to dominate over calculation time per iteration. Such a scalability study is necessary for large grid sizes in order to determine optimal number of MPI nodes and OpenMP threads per node.

  16. TIMEX: a time-dependent explicit discrete ordinates program for the solution of multigroup transport equations with delayed neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Hill, T.R.; Reed, W.H.

    1976-01-01

    TIMEX solves the time-dependent, one-dimensional multigroup transport equation with delayed neutrons in plane, cylindrical, spherical, and two-angle plane geometries. Both regular and adjoint, inhomogeneous and homogeneous problems subject to vacuum, reflective, periodic, white, albedo or inhomogeneous boundary flux conditions are solved. General anisotropic scattering is allowed and anisotropic inhomogeneous sources are permitted. The discrete ordinates approximation for the angular variable is used with the diamond (central) difference approximation for the angular extrapolation in curved geometries. A linear discontinuous finite element representation for the angular flux in each spatial mesh cell is used. The time variable is differenced by an explicit technique that is unconditionally stable so that arbitrarily large time steps can be taken. Because no iteration is performed the method is exceptionally fast in terms of computing time per time step. Two acceleration methods, exponential extrapolation and rebalance, are utilized to improve the accuracy of the time differencing scheme. Variable dimensioning is used so that any combination of problem parameters leading to a container array less than MAXCOR can be accommodated. The running time for TIMEX is highly problem-dependent, but varies almost linearly with the total number of unknowns and time steps. Provision is made for creation of standard interface output files for angular fluxes and angle-integrated fluxes. Five interface units (use of interface units is optional), five output units, and two system input/output units are required. A large bulk memory is desirable, but may be replaced by disk, drum, or tape storage. 13 tables, 9 figures. (auth)

  17. TIMEX: a time-dependent explicit discrete ordinates program for the solution of multigroup transport equations with delayed neutrons

    International Nuclear Information System (INIS)

    TIMEX solves the time-dependent, one-dimensional multigroup transport equation with delayed neutrons in plane, cylindrical, spherical, and two-angle plane geometries. Both regular and adjoint, inhomogeneous and homogeneous problems subject to vacuum, reflective, periodic, white, albedo or inhomogeneous boundary flux conditions are solved. General anisotropic scattering is allowed and anisotropic inhomogeneous sources are permitted. The discrete ordinates approximation for the angular variable is used with the diamond (central) difference approximation for the angular extrapolation in curved geometries. A linear discontinuous finite element representation for the angular flux in each spatial mesh cell is used. The time variable is differenced by an explicit technique that is unconditionally stable so that arbitrarily large time steps can be taken. Because no iteration is performed the method is exceptionally fast in terms of computing time per time step. Two acceleration methods, exponential extrapolation and rebalance, are utilized to improve the accuracy of the time differencing scheme. Variable dimensioning is used so that any combination of problem parameters leading to a container array less than MAXCOR can be accommodated. The running time for TIMEX is highly problem-dependent, but varies almost linearly with the total number of unknowns and time steps. Provision is made for creation of standard interface output files for angular fluxes and angle-integrated fluxes. Five interface units (use of interface units is optional), five output units, and two system input/output units are required. A large bulk memory is desirable, but may be replaced by disk, drum, or tape storage. 13 tables, 9 figures

  18. Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.

    Science.gov (United States)

    Luna-Zurita, Luis; Prados, Belén; Grego-Bessa, Joaquim; Luxán, Guillermo; del Monte, Gonzalo; Benguría, Alberto; Adams, Ralf H; Pérez-Pomares, José María; de la Pompa, José Luis

    2010-10-01

    Cardiac valve formation is crucial for embryonic and adult heart function. Valve malformations constitute the most common congenital cardiac defect, but little is known about the molecular mechanisms regulating valve formation and homeostasis. Here, we show that endocardial Notch1 and myocardial Bmp2 signal integration establish a valve-forming field between 2 chamber developmental domains. Patterning occurs through the activation of endocardial epithelial-to-mesenchymal transition (EMT) exclusively in prospective valve territories. Mice with constitutive endocardial Notch1 activity ectopically express Hey1 and Heyl. They also display an activated mesenchymal gene program in ventricles and a partial (noninvasive) EMT in vitro that becomes invasive upon BMP2 treatment. Snail1, TGF-β2, or Notch1 inhibition reduces BMP2-induced ventricular transformation and invasion, whereas BMP2 treatment inhibits endothelial Gsk3β, stabilizing Snail1 and promoting invasiveness. Integration of Notch and Bmp2 signals is consistent with Notch1 signaling being attenuated after myocardial Bmp2 deletion. Notch1 activation in myocardium extends Hey1 expression to nonchamber myocardium, represses Bmp2, and impairs EMT. In contrast, Notch deletion abrogates endocardial Hey gene transcription and extends Bmp2 expression to the ventricular endocardium. This embryonic Notch1-Bmp2-Snail1 relationship may be relevant in adult valve disease, in which decreased NOTCH signaling causes valve mesenchyme cell formation, fibrosis, and calcification. PMID:20890042

  19. The relationships between field dependent/independent cognitive styles and information & communication technologies based programs in gifted education

    Directory of Open Access Journals (Sweden)

    Hakan Üstünel

    2015-08-01

    Full Text Available The research aims to investigate gifted students’ FD/FI cognitive styles and factors affecting them like preferring to take Information & Communication Technologies-based courses at gifted children’s school. The study was carried out on two groups.  First group consisted of 52 students identified as gifted who are attending 6th and 7th grades at the Istanbul Science &Art Center in Istanbul, Turkey,  the second group consisted of 38 students who are not identified as gifted and totally the study consists of 90 students. In order to collect data pertaining to this research, Group Embedded Figures Test (GEFT was used to measure Field Dependence/Field Independence, (FD/FI.  According to the findings of the research, it has been observed that there is a significant difference between favored gifted students’ cognitive style scores and other students’ who are not identified as gifted. There is also a significant difference between in favor of Information& Communication Technologies (ICT based course taking gifted students’ cognitive style scores and other gifted students who are not taking ICT-based courses in Science and Art Center. In contrast to these, there is not a significant differences were found on cognitive styles in terms of gender and grade variants in both groups.

  20. Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis.

    Science.gov (United States)

    Gillies, G E; Virdee, K; McArthur, S; Dalley, J W

    2014-06-01

    The knowledge that diverse populations of dopaminergic neurons within the ventral tegmental area (VTA) can be distinguished in terms of their molecular, electrophysiological and functional properties, as well as their differential projections to cortical and subcortical regions has significance for key brain functions, such as the regulation of motivation, working memory and sensorimotor control. Almost without exception, this understanding has evolved from landmark studies performed in the male sex. However, converging evidence from both clinical and pre-clinical studies illustrates that the structure and functioning of the VTA dopaminergic systems are intrinsically different in males and females. This may be driven by sex differences in the hormonal environment during adulthood ('activational' effects) and development (perinatal and/or pubertal 'organizational' effects), as well as genetic factors, especially the SRY gene on the Y chromosome in males, which is expressed in a sub-population of adult midbrain dopaminergic neurons. Stress and stress hormones, especially glucocorticoids, are important factors which interact with the VTA dopaminergic systems in order to achieve behavioral adaptation and enable the individual to cope with environmental change. Here, also, there is male/female diversity not only during adulthood, but also in early life when neurobiological programing by stress or glucocorticoid exposure differentially impacts dopaminergic developmental trajectories in male and female brains. This may have enduring consequences for individual resilience or susceptibility to pathophysiological change induced by stressors in later life, with potential translational significance for sex bias commonly found in disorders involving dysfunction of the mesocorticolimbic dopaminergic systems. These findings highlight the urgent need for a better understanding of the sexual dimorphism in the VTA if we are to improve strategies for the prevention and treatment of

  1. Fortran and C programs for the time-dependent dipolar Gross-Pitaevskii equation in an anisotropic trap

    Science.gov (United States)

    Kumar, R. Kishor; Young-S., Luis E.; Vudragović, Dušan; Balaž, Antun; Muruganandam, Paulsamy; Adhikari, S. K.

    2015-10-01

    Many of the static and dynamic properties of an atomic Bose-Einstein condensate (BEC) are usually studied by solving the mean-field Gross-Pitaevskii (GP) equation, which is a nonlinear partial differential equation for short-range atomic interaction. More recently, BEC of atoms with long-range dipolar atomic interaction are used in theoretical and experimental studies. For dipolar atomic interaction, the GP equation is a partial integro-differential equation, requiring complex algorithm for its numerical solution. Here we present numerical algorithms for both stationary and non-stationary solutions of the full three-dimensional (3D) GP equation for a dipolar BEC, including the contact interaction. We also consider the simplified one- (1D) and two-dimensional (2D) GP equations satisfied by cigar- and disk-shaped dipolar BECs. We employ the split-step Crank-Nicolson method with real- and imaginary-time propagations, respectively, for the numerical solution of the GP equation for dynamic and static properties of a dipolar BEC. The atoms are considered to be polarized along the z axis and we consider ten different cases, e.g., stationary and non-stationary solutions of the GP equation for a dipolar BEC in 1D (along x and z axes), 2D (in x- y and x- z planes), and 3D, and we provide working codes in Fortran 90/95 and C for these ten cases (twenty programs in all). We present numerical results for energy, chemical potential, root-mean-square sizes and density of the dipolar BECs and, where available, compare them with results of other authors and of variational and Thomas-Fermi approximations.

  2. Analysis program based on finite element method, MULTI(FEM), for evaluation of dose-dependent local disposition of drug in liver.

    Science.gov (United States)

    Fukumura, K; Yamaoka, K; Higashimori, M; Nakagawa, T

    1999-05-01

    A curve-fitting program based on the Finite Element Method, MULTI(FEM), was developed to model nonlinear local disposition of a drug in the liver under non-steady-state conditions. The program was written in FORTRAN on an IBM-compatible personal computer. The validity of MULTI(FEM) was confirmed by analyzing the outflow kinetics of oxacillin (a model drug) following a pulse input to isolated, perfused rat livers, according to both linear and nonlinear dispersion models. Four dose levels (300, 1000, 3000, and 5000 microg) of oxacillin were administered to observe the dose-dependency in the hepatic local disposition. First, the individual outflow time-profiles at the same dose were averaged, and the average time-profile was analyzed by MULTI(FEM) based on linear dispersion models to yield a single curve fit. The fitted parameters at each dose level were compared with parameters estimated using MULTI(FILT), a program based on fast inverse Laplace transform, to analyze linear pharmacokinetics. The estimated parameters by MULTI(FEM) were in good agreement with those by MULTI(FILT). The apparent elimination rate constant (ke) decreased with an increase in dose, whereas other parameters showed no discernible dependency on an increase of dose. Second, the average outflow time-profiles at the four dose levels were simultaneously analyzed by MULTI(FEM) based on dispersion models featuring Michaelis-Menten elimination. The outflow time-profiles of oxacillin were well approximated by a two-compartment dispersion model with central Michaelis-Menten elimination. The maximum elimination rate constant (Vmax) and the Michaelis constant (Km) were estimated to be 1520 microg/mL/min and 41.3 microg/mL, respectively. Thus, the capability of MULTI(FEM) was demonstrated in evaluating capacity-limited local disposition in the liver. PMID:10229646

  3. Prenatal stress programs neuroendocrine stress responses and affective behaviors in second generation rats in a sex-dependent manner.

    Science.gov (United States)

    Grundwald, Natalia J; Brunton, Paula J

    2015-12-01

    with controls, with no differences in the F2 females. No differences in depressive-like behavior (sucrose preference or forced swim test) were observed in either sex. In conclusion, the effects of maternal stress during pregnancy on HPA axis regulation and anxiety-like behavior can be transmitted to future generations in a sex-dependent manner. These data have implications for human neuropsychiatric disorders with developmental origins. PMID:26318631

  4. Hood River production program monitoring and evaluation. Report A: Hood River and Pelton Ladder evaluation studies. Annual report for 1996

    International Nuclear Information System (INIS)

    In 1992, the Northwest Power Planning Council approved the Hood River and Pelton Ladder master plans within the framework of the Columbia River Basin Fish and Wildlife Program. The master plans define an approach for implementing a hatchery supplementation program in the Hood River subbasin. The hatchery program, as defined in the master plans, is called the Hood River Production Program (HRPP). The HRPP will be implemented at a reduced hatchery production level until (1) the construction of all proposed hatchery facilities has been completed and (2) numbers of returning wild jack and adult fish are sufficient to meet broodstock collection goals. It is anticipated that construction on the hatchery production facilities will be completed by the spring of 1998. The HRPP is jointly implemented by the Oregon Department of Fish and Wildlife (ODFW) and the Confederated Tribes of the Warm Springs (CTWS) Reservation

  5. Bio-Psycho-Spiritual Modeling in Drug Dependents and Compiling of Intervention Program for Promotion of Resiliency Based on Cognitive Narratology and Positive Psychology

    Directory of Open Access Journals (Sweden)

    Ezat ollah Kordmirza Nikoozadeh

    2009-08-01

    Full Text Available Introduction: Since the past few decades, the concentration of researches on drug abuse and drugs dependency have shift from risk factor to protective factors. In the past two decades, the concept of resiliency was increasingly considered by developmental psychology. The concentration shifted from risk to resiliency originates from disadvantage in emphasizing on identification of risk factors. Method: Target population was all volunteer addicts who referred to clinics in Tehran city. The group selected based on random cluster sampling. In total 319 persons (male composed of two groups, dependent to drug (150 persons and independent to drug (169 persons were participated in research and in general, 108 questionnaires of non-addicts and 126 of addicts were analyzed. In order to determine the fit model based on assumed variables in the research, by utilizing LISREL softwar99e, initially the relation between primary fundamental variables and final endogenous variables were reviewed. In continuation, the - relations between intermediary and endogenous variables were determined. Results: The results showed the fitting of predicted model of resiliency. Conclusion: In this research the program based on bio-psycho-spiritual model for instructional intervention in order to enhance of resiliency of addict people provided.

  6. Image transformation into device-dependent color printer description using 4th-order polynomial regression and object-oriented programming development of image processing modules

    Science.gov (United States)

    Mongeon, Michael C.

    1996-03-01

    This paper investigates the development of printer device profiles used in color document printing system environments when devices with intrinsically different gamut capabilities communicate with one another in a common (CIELAB) color space. While the main thrust of this activity focuses on the output printer, namely the Xerox 5760 printer, and its rendition of some device independent image description, characterizations are provided which investigate relative areas of photographic, monitor, and printer gamuts using a visual hue leaf comparison between devices. The printer is modeled using 4th-order polynomial regression which maps the device independent CIELAB image representation into device dependent printer CMYK. This technique results in 1.89 AEEavg over the training data set. Some key properties of the proposed calibration method are as follows: (1) Linearized CMYK tone reproduction curves with respect to AEEpaper to improve the distribution of calibration data in color space. (2) Application of GCR strategy and linearization to the calibration target prior to the regression on the measured CIELAB and original CMY values. Each strategy employs a K addition/No CMY removal method which maximizes printer gamut and relies on the regression to determine the appropriate CMY removal. The following GCR strategies are explored: CMY only (0% K addition), 50% K addition, 100% K addition, and non-linear K addition. A library of image processing algorithms is included, using LabView object oriented programming, which provides a modular approach for key color processing tasks. In the user interface, an image is selected with appropriate GCR strategy, and the program operates on the image. In general, the pictorial image quality is excellent for each GCR strategy with subtle differences between GCR approaches. Quantitative analysis of Q60 color matching performance is included.

  7. Pneumococal Surface Protein A (PspA Regulates Programmed Death Ligand 1 Expression on Dendritic Cells in a Toll-Like Receptor 2 and Calcium Dependent Manner.

    Directory of Open Access Journals (Sweden)

    Mohit Vashishta

    Full Text Available Pneumonia leads to high mortality in children under the age of five years worldwide, resulting in close to 20 percent of all deaths in this age group. Therefore, investigations into host-pathogen interactions during Streptococcus pneumoniae infection are key in devising strategies towards the development of better vaccines and drugs. To that end, in this study we investigated the role of S. pneumoniae and its surface antigen Pneumococcal surface protein A (PspA in modulating the expression of co-stimulatory molecule Programmed Death Ligand 1 (PD-L1 expression on dendritic cells (DCs and the subsequent effects of increased PD-L1 on key defence responses. Our data indicate that stimulation of DCs with PspA increases the surface expression of PD-L1 in a time and dose dependent manner. Characterization of mechanisms involved in PspA induced expression of PD-L1 indicate the involvement of Toll-Like Receptor 2 (TLR2 and calcium homeostasis. While calcium release from intracellular stores positively regulated PD-L1 expression, calcium influx from external milieu negatively regulated PD-L1 expression. Increase in PD-L1 expression, when costimulated with PspA and through TLR2 was higher than when stimulated with PspA or through TLR2. Further, knockdown of TLR2 and the intermediates in the TLR signaling machinery pointed towards the involvement of a MyD88 dependent pathway in PspA induced PD-L1 expression. Incubation of DCs with S. pneumoniae resulted in the up-regulation of PD-L1 expression, while infection with a strain lacking surface PspA failed to do so. Our data also suggests the role of PspA in ROS generation. These results suggest a novel and specific role for PspA in modulating immune responses against S. pneumoniae by regulating PD-L1 expression.

  8. Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment.

    Science.gov (United States)

    Tichy, Elisia D; Stephan, Zachary A; Osterburg, Andrew; Noel, Greg; Stambrook, Peter J

    2013-05-01

    Embryonic stem cells (ESCs) are hypersensitive to many DNA damaging agents and can rapidly undergo cell death or cell differentiation following exposure. Treatment of mouse ESCs (mESCs) with etoposide (ETO), a topoisomerase II poison, followed by a recovery period resulted in massive cell death with characteristics of a programmed cell death pathway (PCD). While cell death was both caspase- and necroptosis-independent, it was partially dependent on the activity of lysosomal proteases. A role for autophagy in the cell death process was eliminated, suggesting that ETO induces a novel PCD pathway in mESCs. Inhibition of p53 either as a transcription factor by pifithrin α or in its mitochondrial role by pifithrin μ significantly reduced ESC death levels. Finally, EndoG was newly identified as a protease participating in the DNA fragmentation observed during ETO-induced PCD. We coined the term charontosis after Charon, the ferryman of the dead in Greek mythology, to refer to the PCD signaling events induced by ETO in mESCs. PMID:23500643

  9. Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

    Science.gov (United States)

    Tilstra, Jeremy S.; Gaddy, Daniel F.; Zhao, Jing; Davé, Shaival H.; Niedernhofer, Laura J.; Plevy, Scott E.; Robbins, Paul D.

    2014-01-01

    Monocyte-derived antigen presenting cells (APC) are central mediators of the innate and adaptive immune response in inflammatory diseases. As such, APC are appropriate targets for therapeutic intervention to ameliorate certain diseases. APC differentiation, activation and functions are regulated by the NF-κB family of transcription factors. Herein, we examined the effect of NF-κB inhibition, via suppression of the IκB Kinase (IKK) complex, on APC function. Murine bone marrow-derived macrophages and dendritic cells (DC), as well as macrophage and DC lines, underwent rapid programmed cell death (PCD) after treatment with several IKK/NF-κB inhibitors through a TNFα-dependent mechanism. PCD was induced proximally by reactive oxygen species (ROS) formation, which causes a loss of mitochondrial membrane potential and activation of a caspase signaling cascade. NF-κB-inhibition-induced PCD of APC may be a key mechanism through which therapeutic targeting of NF-κB reduces inflammatory pathologies.

  10. Financiamiento de programas de farmacodependencia en la ciudad de México: 1990-1994 Financing of drug dependency programs in Mexico City: 1990-1994

    Directory of Open Access Journals (Sweden)

    Irene M. Parada-Toro

    2000-04-01

    Full Text Available OBJETIVO: Analizar el flujo del financiamiento de los programas de farmacodependencia en la ciudad de México, sus fuentes y asignaciones. MATERIAL Y MÉTODOS: Se seleccionó un grupo discreto de instituciones dedicadas a la prevención y el control de la farmacodependencia en la ciudad de México, incluyendo a las instituciones públicas más importantes en el ramo. Se aplicaron encuestas entre administradores y usuarios. Además de integrar los flujos financieros se determinó el gasto por usuario de cada institución. Para el periodo 1990-1993, los gastos se estimaron a partir de los montos financieros asignados a cada programa en 1990 y a valores constantes, para eliminar el efecto de la inflación. RESULTADOS: Las fuentes de financiamiento de las instituciones del grupo estudiado son diversas: de 50 a 90% provienen del presupuesto federal; de 10 a 20%, de aportaciones de los usuarios, y de 15 a 80%, de contribuciones de organizaciones no gubernamentales. CONCLUSIONES: Aunque se han incrementado los montos financieros, en los últimos cuatro años, son insuficientes para el desarrollo de los programas en las instituciones de este estudio, ante la creciente demanda. Se requiere establecer mecanismos que aseguren la captación de recursos necesarios y su uso eficiente. El análisis financiero continuo de estos programas permitirá la toma de decisiones oportuna y una evaluación de los cambios.OBJECTIVE: To analyze the financial flows in the drug dependency programs in México City, their financial source, and the way how funding monies are spent. MATERIAL AND METHODS: A discrete number of institutions devoted to drug dependency control in Mexico City was selected. Analysis of financial flows was carried out using the National Health Accounts methods. Questionnaires to quantify resources were applied to health service managers and users. In addition to collection of financial flow data, we calculated the expenditures per user for each

  11. Multiplex PCR panel of microsatellite markers for the tambaqui, Colossoma macropomum, developed as a tool for use in conservation and broodstock management.

    Science.gov (United States)

    Hamoy, I G; Santos, S

    2012-01-01

    The tambaqui, Colossoma macropomum, native to Brazil, is widely used in aquaculture systems. We developed a multiplex PCR panel for this species, comprising 12 microsatellite loci. This panel was used to genotype 73 specimens collected from Juruti, a city in the Brazilian Amazon. The mean number of alleles per locus was 8.8, the mean observed heterozygosity was 0.76, and the combined power of discrimination and the combined power of exclusion were 0.99999999999999993 and 0.999991762, respectively. We observed no significant deviation from Hardy-Weinberg equilibrium in this population. All amplified alleles were clearly typed, and easily interpretable results were obtained. This method will be useful for paternity analysis, population genetics and conservation studies, as well as for selective breeding programs for C. macropomum. PMID:22370880

  12. ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells.

    Science.gov (United States)

    Berger, Ryan P; Sun, Yu Hua; Kulik, Michael; Lee, Jin Kyu; Nairn, Alison V; Moremen, Kelley W; Pierce, Michael; Dalton, Stephen

    2016-07-01

    Polysialic acid (PSA) is a carbohydrate polymer of repeating α-2,8 sialic acid residues that decorates multiple targets, including neural cell adhesion molecule (NCAM). PST and STX encode the two enzymes responsible for PSA modification of target proteins in mammalian cells, but despite widespread polysialylation in embryonic development, the majority of studies have focused strictly on the role of PSA in neurogenesis. Using human pluripotent stem cells (hPSCs), we have revisited the developmental role of PST and STX and show that early progenitors of the three embryonic germ layers are polysialylated on their cell surface. Changes in polysialylation can be attributed to lineage-specific expression of polysialyltransferase genes; PST is elevated in endoderm and mesoderm, while STX is elevated in ectoderm. In hPSCs, PST and STX genes are epigenetically marked by overlapping domains of H3K27 and H3K4 trimethylation, indicating that they are held in a "developmentally-primed" state. Activation of PST transcription during early mesendoderm differentiation is under control of the T-Goosecoid transcription factor network, a key regulatory axis required for early cell fate decisions in the vertebrate embryo. This establishes polysialyltransferase genes as part of a developmental program associated with germ layer establishment. Finally, we show by shRNA knockdown and CRISPR-Cas9 genome editing that PST-dependent cell surface polysialylation is essential for endoderm specification. This is the first report to demonstrate a role for a glycosyltransferase in hPSC lineage specification. Stem Cells 2016;34:1742-1752. PMID:27074314

  13. Impact of a school-based disordered eating prevention program in adolescent girls: general and specific effects depending on adherence to the interactive activities.

    Science.gov (United States)

    López-Guimerà, Gemma; Sánchez-Carracedo, David; Fauquet, Jordi; Portell, Mariona; Raich, Rosa M

    2011-05-01

    This study assessed the impact of a school-based program aimed at preventing disordered eating. The program was based on the media-literacy approach and has interactive format. The program was assessed under strong methodological conditions. Seven schools with 263 Spanish adolescent girls in the area of Barcelona, were randomly assigned to either the complete prevention program condition, the partial program condition or the non-treatment control condition, and assessed at pre, post and 6-month follow-up. The program was effective in generating positive changes at follow-up. The effects sizes (ES(d) = 0.29 to ES(d) = 0.38) were greater, on average, than that obtained up to now in selective-universal programs, and similar or greater than that achieved by targeted prevention programs. The results indicate a greater and relevant effect size of the intervention in those participants who completed the inter-session interactive activities (ES(d) = 0.29 to ES(d) = 0.45) although the differences were not significant. These results suggest the importance of monitoring adherence to the activities in all programs defined as "interactive". The implications and limitations of this study are discussed. PMID:21568186

  14. OpenMP Fortran and C programs for solving the time-dependent Gross-Pitaevskii equation in an anisotropic trap

    CERN Document Server

    Young-S., Luis E; Muruganandam, Paulsamy; Adhikari, Sadhan K; Balaz, Antun

    2016-01-01

    We present new version of previously published Fortran and C programs for solving the Gross-Pitaevskii equation for a Bose-Einstein condensate with contact interaction in one, two and three spatial dimensions in imaginary and real time, yielding both stationary and non-stationary solutions. To reduce the execution time on multicore processors, new versions of parallelized programs are developed using Open Multi-Processing (OpenMP) interface. The input in the previous versions of programs was the mathematical quantity nonlinearity for dimensionless form of Gross-Pitaevskii equation, whereas in the present programs the inputs are quantities of experimental interest, such as, number of atoms, scattering length, oscillator length for the trap, etc. New output files for some integrated one- and two-dimensional densities of experimental interest are given. We also present speedup test results for the new programs.

  15. OpenMP Fortran and C programs for solving the time-dependent Gross-Pitaevskii equation in an anisotropic trap

    Science.gov (United States)

    Young-S., Luis E.; Vudragović, Dušan; Muruganandam, Paulsamy; Adhikari, Sadhan K.; Balaž, Antun

    2016-07-01

    We present new version of previously published Fortran and C programs for solving the Gross-Pitaevskii equation for a Bose-Einstein condensate with contact interaction in one, two and three spatial dimensions in imaginary and real time, yielding both stationary and non-stationary solutions. To reduce the execution time on multicore processors, new versions of parallelized programs are developed using Open Multi-Processing (OpenMP) interface. The input in the previous versions of programs was the mathematical quantity nonlinearity for dimensionless form of Gross-Pitaevskii equation, whereas in the present programs the inputs are quantities of experimental interest, such as, number of atoms, scattering length, oscillator length for the trap, etc. New output files for some integrated one- and two-dimensional densities of experimental interest are given. We also present speedup test results for the new programs.

  16. Three FORTRAN programs for finite-difference solutions to binary diffusion in one and two phases with composition-and time-dependent diffusion coefficients

    Science.gov (United States)

    Sanford, R.F.

    1982-01-01

    Geological examples of binary diffusion are numerous. They are potential indicators of the duration and rates of geological processes. Analytical solutions to the diffusion equations generally do not allow for variable diffusion coefficients, changing boundary conditions, and impingement of diffusion fields. The three programs presented here are based on Crank-Nicholson finite-difference approximations, which can take into account these complicating factors. Program 1 describes the diffusion of a component into an initially homogeneous phase that has a constant surface composition. Specifically it is written for Fe-Mg exchange in olivine at oxygen fugacities appropriate for the lunar crust, but other components, phases, or fugacities may be substituted by changing the values of the diffusion coefficient. Program 2 simulates the growth of exsolution lamellae. Program 3 describes the growth of reaction rims. These two programs are written for pseudobinary Ca-(Mg, Fe) exchange in pyroxenes. In all three programs, the diffusion coefficients and boundary conditions can be varied systematically with time. To enable users to employ widely different numerical values for diffusion coefficients and diffusion distance, the grid spacing in the space dimension and the increment by which the grid spacing in the time dimension is increased at each time step are input constants that can be varied each time the programs are run to yield a solution of the desired accuracy. ?? 1982.

  17. Desempeño reproductivo de dos líneas de reproductores de camarón blanco Litopenaeus vannamei introducidos en Cuba - Reproductive behaviour of broodstocks from lines of white shrimp Litopenaeus vannamei introducing in Cuba

    Directory of Open Access Journals (Sweden)

    Lic. Missael Guerra

    2010-07-01

    Full Text Available ResumenUno de los mayores problemas en los laboratorios de producción depostlarvas es el “inbreeding”, el que puede afectar las características reproductivas de los animales y tener un impacto negativo en la producción. En este trabajo se evaluaron los registros reproductivos de los progenitores de dos introducciones (I1 e I3 de camarón blanco Litopenaeus vannamei provenientes del mismo lugar mantenidos en ciclo de producción cerrado. Para el estudio se tomaron los resultados del número de hembras maduras diarias (Mad/día; Porciento de cópula (% Cop y nauplios por desove (Nau/Des. Todos estos indicadores fueron comparados entre meses y entre introducciones. El número de hembras maduras fue el único que mostró una distribución normal variando de 119 a 178 y de 43 a 70 para cada una de las introducciones respectivamente. Se observó que existen diferencias significativas entre los meses en todos para los indicadores. Se observó un comportamiento similar de loscaracteres reproductivos, el segundo y tercer mes fueron los mejoresdurante el período de producción. No existieron diferencias significativas en el porciento de cópula ni en el número de nauplios por desoves, pero en el número de hembras maduras si hubo diferencias mostrando valores de 160 para I1 y de 62 para I3; esto probablemente se debe a problemas de manejo, el número de animales que se encontraban en la nave o a condiciones ambientales. Estos parámetros son muy importantes para la diferenciación genética entre líneas, además de ser muy útiles en un posible tratamiento de loci cuantitativo (QTL, por sus siglas en ingles que permitan mejoras los caracteres reproductivos y así obtener reproductores más eficientes.SummaryOne of the major concerns in hatcheries is inbreeding, which can affect fitness-related traits, and may have a significant negative impact on production. We present the analysis of reproductive records for broodstocks from two different

  18. Provenance as Dependency Analysis

    CERN Document Server

    Cheney, James; Acar, Umut

    2007-01-01

    Provenance is information recording the source, derivation, or history of some information. Provenance tracking has been studied in a variety of settings; however, although many design points have been explored, the mathematical or semantic foundations of data provenance have received comparatively little attention. In this paper, we argue that dependency analysis techniques familiar from program analysis and program slicing provide a formal foundation for forms of provenance that are intended to show how (part of) the output of a query depends on (parts of) its input. We introduce a semantic characterization of such dependency provenance, show that this form of provenance is not computable, and provide dynamic and static approximation techniques.

  19. Disruption of the vacuolar calcium-ATPases in arabidopsis results in the activation of a salicylic acid-dependent programmed cell death pathway

    Science.gov (United States)

    Calcium (Ca2+) signals regulate many aspects of plant development, including the Hypersensitive Response (HR) that triggers a programmed cell death response to protect a plant from a pathogen. A transient increase in cytosolic Ca2+ ([Ca2+]cyt ) results from Ca2+ entry from the apoplast or release fr...

  20. The effect of a structured education program on knowledge and psychomotor skills of patients using beclomethasone dipropionate aerosol for steroid dependent asthma.

    Science.gov (United States)

    Heringa, P; Lawson, L; Reda, D

    1987-01-01

    The purpose of the study was to evaluate the efficacy of a structured education program on knowledge and psychomotor skills of subjects using inhaled beclomethasone dipropionate. The sample was comprised of 26 male outpatients with a mean age of sixty years (range 49-69 yrs) and mean educational level of 11 years (range 7-18 yrs). Subjects were tested to assess knowledge of drug action, self-administration, and side effects. Skill in self-administration was assessed by two independent raters who were blind to group assignment. Then, patients were randomly assigned to an experimental group (n = 13), who received a structured educational program, or a control group (n = 13), who received no structured educational interventions. Patients were retested four weeks after randomization. Subjects in the experimental and control groups did not differ significantly with respect to their initial mean knowledge and performance scores. The post-test mean knowledge score was significantly higher when compared to initial score for each group. Mean knowledge score at post-test did not differ significantly between groups. However, when comparing post-test performance scores to initial scores the experimental group had a significantly greater increase in mean score than the control group. It is concluded that a structured patient education program is an effective method for improving the psychomotor skills necessary for proper use of beclomethasone dipropionate aerosol. PMID:3654237

  1. Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4

    OpenAIRE

    Fernandez-Boyanapalli, Ruby F.; Frasch, S. Courtney; McPhillips, Kathleen; Vandivier, R. William; Harry, Brian L.; Riches, David W.H.; Henson, Peter M.; Bratton, Donna L.

    2009-01-01

    Chronic granulomatous disease (CGD) is characterized by overexuberant inflammation and autoimmunity that are attributed to deficient anti-inflammatory signaling. Although regulation of these processes is complex, phosphatidylserine (PS)–dependent recognition and removal of apoptotic cells (efferocytosis) by phagocytes are potently anti-inflammatory. Since macrophage phenotype also plays a beneficial role in resolution of inflammation, we hypothesized that impaired efferocytosis in CGD due to ...

  2. Exercise Dependence

    OpenAIRE

    Erdal Vardar

    1987-01-01

    Exercise dependence define a condition in which a person performs excessive exercise resulting in deterioration of his or her physical and mental health wellness. Despite many clinical research studies on exercise dependence, exact diagnostic criteria has not been developed yet. Clinical evidences concerning etiology, epidemiology, underlying mechanisms and treatment of exercise dependence are still not sufficient. Moreover, evaluation of this clinical disorder within dependency perspective i...

  3. Exercise Dependence

    OpenAIRE

    Vardar, Erdal

    2012-01-01

    Exercise dependence define a condition in which a person performs excessive exercise resulting in deterioration of his or her physical and mental health wellness. Despite many clinical research studies on exercise dependence, exact diagnostic criteria has not been developed yet. Clinical evidences concerning etiology, epidemiology, underlying mechanisms and treatment of exercise dependence are still not sufficient. Moreover, evaluation of this clinical disorder within dependency perspective...

  4. Methods, Devices and Computer Program Products Providing for Establishing a Model for Emulating a Physical Quantity Which Depends on at Least One Input Parameter, and Use Thereof

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention proposes methods, devices and computer program products. To this extent, there is defined a set X including N distinct parameter values x_i for at least one input parameter x, N being an integer greater than or equal to 1, first measured the physical quantity Pm1 for each of...... the N distinct parameter values x_i of the at least one input parameter x, while keeping all other input parameters fixed, constructed a Vandermonde matrix VM using the set of N parameter values x_i of the at least one input parameter x, and computed the model W for emulating the physical quantity P...

  5. Provenance as Dependency Analysis

    OpenAIRE

    Cheney, James; Ahmed, Amal; Acar, Umut,

    2007-01-01

    Provenance is information recording the source, derivation, or history of some information. Provenance tracking has been studied in a variety of settings; however, although many design points have been explored, the mathematical or semantic foundations of data provenance have received comparatively little attention. In this paper, we argue that dependency analysis techniques familiar from program analysis and program slicing provide a formal foundation for forms of provenance that are intende...

  6. Size-dependent properties of transition metal clusters: from molecules to crystals and surfaces--computational studies with the program ParaGauss.

    Science.gov (United States)

    Soini, Thomas M; Rösch, Notker

    2015-11-21

    In the so-called scalable regime the size-dependent behavior of the physical and chemical properties of transition metal clusters is described by scaling relationships. For most quantities this scalable regime is reached for cluster sizes between a few tens and a few hundreds of atoms, hence for systems for which an accurate treatment by density functional theory is still feasible. Thus, by invoking scaling relations one is able to obtain properties of very large nanoparticles and even the bulk limit from the results of a series of smaller cluster models. In this invited review we illustrate this strategy by exploiting results from computational studies that mostly were carried out with the density functional theory software ParaGauss. We address mainly the size-dependent behavior of the properties of transition metal clusters. To this end, we first present benchmark studies probing various approximations that are used in such density functional calculations. Subsequently we show how physical insight may be gained by exploring less understood types of systems. These applications range from bare clusters to nanoislands and nanoalloys to adsorption complexes. PMID:26456800

  7. The effects of two-week program of individually measured physical activity on insulin resistance in obese non-insulin-dependent diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Čizmić Milica

    2003-01-01

    Full Text Available It is well known that under the influence of regular, individually measured aerobic physical activity, it is possible to raise the biological efficiency of insulin by several mechanisms: by increasing the number of insulin receptors, their sensitivity and efficiency, as well as by increasing glucose transporters GLUT-4 on the level of cell membrane. The aim of this research was to examine whether decreased insulin resistance could be achieved under the influence of the program of individually measured aerobic physical activity in the 2-week period, in the obese type 2 diabetes patients with the increased aerobic capacity (VO2max. In 10 type 2 diabetes patients 47.6 ± 4.6 years of age (group E, in the 14-days period, program of aerobic training was applied (10 sessions - 35 min session of walking on treadmill, intensity 60.8 ± 5.7% (VO2max, frequency 5 times a week , as well as 1 600 kcal diet. At the same time, other 10 type 2 diabetes patients 45.9 ± 5.5 years of age (group C were on 1 600 kcal diet. Before and after this period the following was measured in both groups: insulin sensitivity (M/I by the method of hyperinsulin euglycemic clamp, and (VO2max by Astrand test on ergocycle. In contrast to the group C, in the second testing of E group subjects a significant increase was obtained in M/I (1.23 ± 0.78 vs. 2.42 ± 0.95 mg/kg/min/mU p<0.001, 96.75% as well as the increase of (VO2max (26.34 ± 4.26 vs. 29.16 ± 5.01 ml/kg/min p<0.05, 10.7%. The results had shown that 2-week program of aerobic training had had significant influence on the increased aerobic capacity and insulin sensitivity in the tested patients.

  8. Dependency Parsing

    CERN Document Server

    Kubler, Sandra; Nivre, Joakim

    2009-01-01

    Dependency-based methods for syntactic parsing have become increasingly popular in natural language processing in recent years. This book gives a thorough introduction to the methods that are most widely used today. After an introduction to dependency grammar and dependency parsing, followed by a formal characterization of the dependency parsing problem, the book surveys the three major classes of parsing models that are in current use: transition-based, graph-based, and grammar-based models. It continues with a chapter on evaluation and one on the comparison of different methods, and it close

  9. [Affective dependency].

    Science.gov (United States)

    Scantamburlo, G; Pitchot, W; Ansseau, M

    2013-01-01

    Affective dependency is characterized by emotional distress (insecure attachment) and dependency to another person with a low self-esteem and reassurance need. The paper proposes a reflection on the definition of emotional dependency and the confusion caused by various denominations. Overprotective and authoritarian parenting, cultural and socio-environmental factors may contribute to the development of dependent personality. Psychological epigenetic factors, such as early socio-emotional trauma could on neuronal circuits in prefronto-limbic regions that are essential for emotional behaviour.We also focus on the interrelations between dependent personality, domestic violence and addictions. The objective for the clinician is to propose a restoration of self-esteem and therapeutic strategies focused on autonomy. PMID:23888587

  10. Drug dependence

    Science.gov (United States)

    ... Problem or risky use. The user loses any motivation; does not care about school and work; has ... withdrawal. Most employers offer referral services for their employees with substance use problems. Prevention Drug education programs ...

  11. Modality-dependent dose requirements in the Austrian breast cancer early detection program. First results from technical quality assurance; Geraeteabhaengiger Dosisbedarf im Oesterreichischen Brustkrebsfrueherkennungsprogramm. Erste Ergebnisse aus der technischen Qualitaetssicherung

    Energy Technology Data Exchange (ETDEWEB)

    Osanna-Elliott, A.; Semturs, F.; Menhart, S.; Schloegl, C.; Wildner, S.; Zwettler, G. [AGES, Wien (Austria). Referenzzentrum fuer technische Qualitaetssicherung im Brustkrebsfrueherkennungsprogramm

    2015-07-01

    The Austrian Breast Cancer Early Detection Program (BKFP) has officially started in January 2014. In order to ensure that all participating women can rely on a sufficient cancer detection rate while at the same time the required dose is as low as reasonably achievable, all participating radiology institutes (approx. 200) have to fulfill strict quality assurance requirements. The control and certification is performed by the Reference Center for Technical Quality Assurance (RefZQS), which has been developing the methods and tolerances in a pilot project since 2007. The limits are defined in the EUREF-Oeprotocol which is based on the European EPQC guidelines. From the requirement for optimized image quality while simultaneously following the ALARA principle, we found modality-dependent dose requirements, which we had expected but which have now been compiled for the first time for Austria.

  12. Diversidad genética de piracanjuba usada en programas de repoblación con marcadores microsatélites Genetic diversity of piracanjuba used in stock enhancement programs with microsatellite markers

    Directory of Open Access Journals (Sweden)

    Maria del Pilar Rodriguez-Rodriguez

    2010-01-01

    Full Text Available El objetivo de este trabajo fue estimar la diversidad genética de un lote de Brycon orbignyanus usado en programas de repoblación, a través de marcadores microsatélites. Se analizaron muestras de 44 reproductores, de 70 larvas y de 69 alevinos, con la amplificación de cinco loci descritos para Brycon opalinus. El número de alelos, la heterozigosidad observada (Ho y esperada (He, el índice de Shannon (IS, la diversidad genética de Nei (DGN, el coeficiente de endogamia (Fis, la distancia (DG e identidad genética (IG, el número efectivo de alelos, el test del equilibrio de Hardy-Weinberg (EHW y el desequilibrio de ligación fueron calculados. Reproductores y progenie tuvieron un número similar de alelos en los loci evaluados. La Ho media, IS, DGN, DG e IG mostraron que existe menor distancia genética entre parentales y larvas y una disminución de variabilidad genética en los alevinos. Fueron observados desvíos en EHW y desequilibrio de ligación en seis pares de loci. El Fis mostró exceso de heterocigotos en parentales y larvas y déficit de heterocigotos en los alevinos. El lote de reproductores está en proceso de pérdida de alelos y hubo disminución de la variabilidad genética entre la fase de larva y alevino.The objective of this work was to estimate the genetic diversity of a Brycon orbignyanus lot used in stock enhancement programs, using microsatellite markers. Samples of 44 broodstocks, 70 larvae and 69 fingerlings, were analyzed with amplification of five loci described for Brycon opalinus. The number of alleles, the observed (Ho and expected (He heterozygosity, Shannon index (IS, Nei's genetic diversity (DGN, the inbreeding coefficient (Fis, distance (DG and genetic identity (IG, the effective number of alleles, the test of Hardy-Weinberg equilibrium (EHW and the linkage disequilibrium were calculated. Broodstocks and offspring had a similar number of alleles at the tested loci. Ho average, IS, DGN, DG and IG showed

  13. Grande Ronde Endemic Spring Chinook Salmon Supplementation Program : Facility Operation and Maintenance Facilities, Annual Report 2003.

    Energy Technology Data Exchange (ETDEWEB)

    McLean, Michael L.; Seeger, Ryan; Hewitt, Laurie (Confederated Tribes of the Umatilla Indian Reservation, Department of Natural Resources, Pendleton, OR)

    2004-01-01

    endemic fish stocks in future artificial propagation programs. The GRESCSSP was implemented in three Grande Ronde River basin tributaries; the Lostine and upper Grande Ronde rivers and Catherine Creek. The GRESCSSP employs two broodstock strategies utilizing captive and conventional brood sources. The captive brood program began in 1995, with the collection of parr from the three tributary areas. The conventional broodstock component of the program began in 1997 with the collection of natural adults returning to these tributary areas. Although LGH was available as the primary production facility for spring chinook programs in the Grande Ronde Basin, there were never any adult or juvenile satellite facilities developed in the tributary areas that were to be supplemented. An essential part of the GRESCSSP was the construction of adult traps and juvenile acclimation facilities in these tributary areas. Weirs were installed in 1997 for the collection of adult broodstock for the conventional component of the program. Juvenile facilities were built in 2000 for acclimation of the smolts produced by the captive and conventional broodstock programs and as release sites within the natural production areas of their natal streams. The Confederated Tribes of the Umatilla Indian Reservation (CTUIR) operate both the juvenile acclimation and adult trapping facilities located on Catherine Creek and the upper Grande Ronde River under this project. The Nez Perce Tribe (NPT) operate the facilities on the Lostine River under a sister project. Hatcheries were also built in Oregon, Washington and Idaho under the LSRCP to compensate for losses of summer steelhead due to the construction and operation of the lowest four Snake River dams. Despite these harvest-driven hatchery programs, natural summer steelhead populations continued to decline as evidenced by declining counts at Lower Granite Dam since 1995 (Columbia River Data Access in Real Time, DART) and low steelhead redd counts on index

  14. Grande Ronde Endemic Spring Chinook Salmon Supplementation Program : Facility Operations and Maintenance, 2004 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McLean, Michael L.; Seeger, Ryan; Hewitt, Laurie (Confederated Tribes of the Umatilla Indian Reservation, Department of Natural Resources, Pendleton, OR)

    2005-02-01

    There were 2 acclimation periods at the Catherine Creek Acclimation Facility (CCAF) in 2004. During the early acclimation period, 92,475 smolts were delivered from Lookingglass Hatchery (LGH) on 8 March. This group was comprised entirely of progeny from the captive broodstock program. The size of the fish at delivery was 23.1 fish/lb. Volitional releases began 15 March 2004 and ended 22 March with an estimated total (based on PIT tag detections of 1,475) of 8,785 fish leaving the raceways. This was 9.5% of the total fish delivered. Fish remaining in the raceways after volitional release were forced out. Hourly detections of PIT-tagged fish showed that most of the fish left between 1200 and 2000 hours which was similar to the hourly temperature profile. The size of the fish just before the volitional release was 23.1 and the size of the fish remaining just before the forced release was 23.5 fish/lb. The total mortality for the acclimation period was 62 (0.07 %). The total number of fish released from the acclimation facility during the early period was 92,413. During the second acclimation period 70,977 smolts were delivered from LGH on 24 March. This group was comprised entirely of progeny from the conventional broodstock program. The size of the fish at delivery was 23.4 fish/lb. Volitional releases began 30 March 2004 and ended 12 April with an estimated total (based on PIT tag detections of 3,632) of 49,147 fish leaving the raceways. This was 69.2% of the total fish delivered. Fish remaining in the raceways after volitional release were forced out. Hourly detections of PIT-tagged fish showed that most of the fish left between 1200 and 2000 hours which was similar to the hourly temperature profile. The size of the fish just before the volitional release was 23.4 and the size of the fish remaining just before the forced release was 23.9 fish/lb. The total mortality for the acclimation period was 18 (0.03 %). The total number of fish released from the acclimation

  15. [Prevention of alcohol dependence].

    Science.gov (United States)

    Trova, A C; Paparrigopoulos, Th; Liappas, I; Ginieri-Coccossis, M

    2015-01-01

    With the exception of cardiovascular diseases, no other medical condition causes more serious dysfunction or premature deaths than alcohol-related problems. Research results indicate that alcohol dependent individuals present an exceptionally poor level of quality of life. This is an outcome that highlights the necessity of planning and implementing preventive interventions on biological, psychological or social level, to be provided to individuals who make alcohol abuse, as well as to their families. Preventive interventions can be considered on three levels of prevention: (a) primary prevention, which is focused on the protection of healthy individuals from alcohol abuse and dependence, and may be provided on a universal, selective or indicated level, (b) secondary prevention, which aims at the prevention of deterioration regarding alcoholic dependence and relapse, in the cases of individuals already diagnosed with the condition and (c) tertiary prevention, which is focused at minimizing deterioration of functioning in chronically sufferers from alcoholic dependence. The term "quaternary prevention" can be used for the prevention of relapse. As for primary prevention, interventions focus on assessing the risk of falling into problematic use, enhancing protective factors and providing information and health education in general. These interventions can be delivered in schools or in places of work and recreation for young people. In this context, various programs have been applied in different countries, including Greece with positive results (Preventure, Alcolocks, LST, SFP, Alcohol Ignition Interlock Device). Secondary prevention includes counseling and structured help with the delivery of programs in schools and in high risk groups for alcohol dependence (SAP, LST). These programs aim at the development of alcohol refusal skills and behaviors, the adoption of models of behaviors resisting alcohol use, as well as reinforcement of general social skills. In the

  16. Phenibut dependence

    OpenAIRE

    Samokhvalov, Andriy V.; Paton-Gay, C Lindsay; Balchand, Kam; Rehm, Jürgen

    2013-01-01

    Phenibut is a γ-aminobutyric acid (GABA) agonist designed and used as an anxiolytic in Russia. In Western countries, phenibut is not a registered medication but is available through online stores as a supplement. We present a case of a patient who used phenibut to self-medicate anxiety, insomnia and cravings for alcohol. While phenibut was helpful initially, the patient developed dependence including tolerance, significant withdrawal symptoms within 3–4 h of last use and failure to fulfil his...

  17. Factores de riesgo/protección y los programas preventivos en drogodependencias en el Perú Risk/protective factors and prevention programs for drug dependence in Peru

    Directory of Open Access Journals (Sweden)

    William Cabanillas-Rojas

    2012-03-01

    Full Text Available Los factores de riesgo/protección (FRP representan elementos fundamentales para el análisis, comprensión y formulación de respuestas preventivas de las drogodependencias. El objetivo de este artículo es mostrar una revisión de la literatura sobre los FRP y sus implicancias en el diseño de programas preventivos. Se focalizará en FRP individual (aspectos genéticos, experiencias tempranas y habilidades psicosociales, familiar (control y monitoreo parental, permisividad, estilos parentales, pares (presión grupal y normas sociales y comunitario (desorganización. De otro lado, se evidencia la necesidad de incorporar un marco conceptual multifactorial para el abordaje preventivo de las drogodependencias, articulando ámbitos de intervención (escolar, familiar y comunitario y la asunción de una perspectiva evolutiva que permita la implementación de acciones sostenidas. Además, se discuten las implicaciones para investigaciones futuras y formulación de políticas públicas.Risk/ protective factors (RPF are main elements for the analysis, understanding and formulation of answers for the prevention of drug dependences. The objective of this article is to present a literature review about the RPF and their implications in the design of preventive programs. It will focus on individual (genetic aspects, early experiences and psicosocial skills, family (parental control and monitoring, permissiveness, parenting styles, peer (group pressure and social norms and communitarian (disorganization RPF. On the other hand, the need of incorporating a multifactor conceptual framework for the preventive approach to drug dependences, articulating the intervention spaces (school, family and community, assuming and evolving perspective allowing the implementations of sustained actions is evidenced. On top, the implications for future research and public policy formulation are discussed.

  18. Phenibut dependence.

    Science.gov (United States)

    Samokhvalov, Andriy V; Paton-Gay, C Lindsay; Balchand, Kam; Rehm, Jürgen

    2013-01-01

    Phenibut is a γ-aminobutyric acid (GABA) agonist designed and used as an anxiolytic in Russia. In Western countries, phenibut is not a registered medication but is available through online stores as a supplement. We present a case of a patient who used phenibut to self-medicate anxiety, insomnia and cravings for alcohol. While phenibut was helpful initially, the patient developed dependence including tolerance, significant withdrawal symptoms within 3-4 h of last use and failure to fulfil his roles at work and at home. He finally sought medical assistance in our addictions clinic. We have gradually, over the course of 9 weeks, substituted phenibut with baclofen, which has similar pharmacological properties, and then successfully tapered the patient off baclofen. This required approximately 10 mg of baclofen for each gram of phenibut. PMID:23391959

  19. A Program Transformation for Backwards Analysis of Logic Programs

    DEFF Research Database (Denmark)

    Gallagher, John Patrick

    2003-01-01

    programs presented here is based on a transformation of the input program, which makes explicit the dependencies of the given program points on the initial goals. The transformation is derived from the resultants semantics of logic programs. The transformed program is then analysed using a standard...

  20. Sherman Creek Hatchery; Washington Department of Fish and Wildlife Fish Program, 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Combs, Mitch (Washington Department of Fish and Wildlife, Kettle Falls, WA)

    2001-03-01

    The Sherman Creek Hatchery (SCH) was designed to rear 1.7 million kokanee fry for acclimation and imprinting during the spring and early summer. Additionally, it was designed to trap all available returning adult kokanee during the fall for broodstock operations and evaluations. Since the start of this program, the operations on Lake Roosevelt have been modified to better achieve program goals. These strategic changes have been the result of recommendations through the Lake Roosevelt Hatcheries Coordination Team (LRHCT) and were done to enhance imprinting, improve survival and operate the two kokanee facilities more effectively. The primary changes have been to replace the kokanee fingerling program with a yearling (post smolt) program of up to 1,000,000 fish. To construct and operate twenty net pens to handle the increased production. The second significant change was to rear 200,000 rainbow trout fingerling at SCH from July through October, for stocking into the volunteer net pens. This enables the Spokane Tribal Hatchery (STH) to rear additional kokanee to further the enhancement efforts on Lake Roosevelt. Monitoring and evaluation is preformed by the Lake Roosevelt Fisheries Monitoring Program. From 1988 to 1998, the principle sport fishery on Lake Roosevelt has shifted from walleye to include rainbow trout and kokanee salmon (Underwood et al. 1997, Tilson and Scholz 1997). The angler use, harvest rates for rainbow and kokanee and the economic value of the fishery has increased substantially during this 10-year period. The most recent information from the monitoring program also suggests that the hatchery and net pen rearing programs have been beneficial to enhancing the Lake Roosevelt fishery while not negatively impacting wild and native stocks within the lake.

  1. Estudio de la Incertidumbre en la Programación de Actividades usando la Matriz de Estructura Dependiente Study of the Uncertainty of Task Programming using the Dependency Structure Matrix

    Directory of Open Access Journals (Sweden)

    Edelmira D Gálvez

    2012-01-01

    Full Text Available Se presenta un estudio sobre el efecto de la incertidumbre en la programación de actividades de proyectos usando la matriz de estructura dependiente (DSM y la teoría gris. Se aplica la teoría gris para representar la incertidumbre en la estimación del tiempo de duración de proyectos, desarrollando las ecuaciones necesarias para determinar el tiempo convencional gris, el tiempo normal gris y el tiempo normal gris con superposición natural. Con base en el estudio se concluye que la aplicación de la teoría de gris a la DSM permite: i considerar la incertidumbre en la programación del proyecto; ii identificar las etapas más críticas; iii analizar el efecto de la incertidumbre de cada etapa en la duración total del proyecto; y iv comparar diferentes estrategias de programación.A study about the effect of uncertainty on the planning of project activities using the dependency structure matrix (DSM and grey theory. The grey theory is applied to represent the uncertainty in estimating project extension. As a result, the equations to determine the grey conventional time, the grey normal time and the grey normal time with natural overlap were developed. Based on the case studies it is concluded that the application of the grey theory to the DSM allows: considering the uncertainty in project planning; ii identifying the most critical stages; iii analyzing the effect of the uncertainty of each stage in the total project duration; and iv comparing different programming strategies.

  2. System dependence graphs in sequential Erlang

    OpenAIRE

    Silva Galiana, Josep Francesc; Tamarit Muñoz, Salvador; TOMÁS FRANCO, CÉSAR

    2012-01-01

    The system dependence graph (SDG) is a data structure used in the imperative paradigm for different static analysis, and particularly, for program slicing. Program slicing allows us to determine the part of a program (called slice) that influences a given variable of interest. Thanks to the SDG, we can produce precise slices for interprocedural programs. Unfortunately, the SDG cannot be used in the functional paradigm due to important features that are not considered in this formalism (e.g., ...

  3. Smokeless Tobacco Reduction Program.

    OpenAIRE

    Glidden, L; Whigam, K

    1987-01-01

    To reduce the incidence and prevalence of oral cancer, the Smokeless Tobacco Reduction Program will consist of a mass media campaign, public oral screening, and a week-long school health program for 350 students in the seventh, eighth, and ninth grades in Willows, Glenn County, CA. Mass media will include radio, television, newspapers, posters, and literature. The program will use resources of the public health department and junior high school; it will also depend on 8 teachers and 25 peer l...

  4. Reasoning about embedded dependencies using inclusion dependencies

    OpenAIRE

    Hannula, Miika

    2015-01-01

    The implication problem for the class of embedded dependencies is undecidable. However, this does not imply lackness of a proof procedure as exemplified by the chase algorithm. In this paper we present a complete axiomatization of embedded dependencies that is based on the chase and uses inclusion dependencies and implicit existential quantification in the intermediate steps of deductions.

  5. Civilian Health and Medical Program of the Uniformed Services (CHAMPUS); TRICARE uniform health maintenance organization (HMO) benefit--Prime enrollment fee exemption for survivors of active duty deceased sponsors and medically retired uniformed services members and their dependents. Final rule.

    Science.gov (United States)

    2014-09-30

    This final rule creates an exception to the usual rule that TRICARE Prime enrollment fees are uniform for all retirees and their dependents and responds to public comments received to the proposed rule published in the Federal Register on June 7, 2013. Survivors of Active Duty Deceased Sponsors and Medically Retired Uniformed Services Members and their Dependents are part of the retiree group under TRICARE rules. In acknowledgment and appreciation of the sacrifices of these two beneficiary categories, the Secretary of Defense has elected to exercise his authority under the United States Code to exempt Active Duty Deceased Sponsors and Medically Retired Uniformed Services Members and their Dependents enrolled in TRICARE Prime from paying future increases to the TRICARE Prime annual enrollment fees. The Prime beneficiaries in these categories have made significant sacrifices for our country and are entitled to special recognition and benefits for their sacrifices. Therefore, the beneficiaries in these two TRICARE beneficiary categories who enrolled in TRICARE Prime prior to 10/1/2013, and those since that date, will have their annual enrollment fee frozen at the appropriate fiscal year rate: FY2011 rate $230 per single or $460 per family, FY2012 rate $260 or $520, FY2013 rate $269.38 or $538.56, or the FY2014 rate $273.84 or $547.68. The future beneficiaries added to these categories will have their fee frozen at the rate in effect at the time they are classified in either category and enroll in TRICARE Prime or, if not enrolling, at the rate in effect at the time of enrollment. The fee remains frozen as long as at least one family member remains enrolled in TRICARE Prime and there is not a break in enrollment. The fee charged for the dependent(s) of a Medically Retired Uniformed Services Member would not change if the dependent(s) was later re-classified a Survivor. PMID:25269153

  6. Characterization of Linkage Disequilibrium in a Rainbow Trout Broodstock Population

    Science.gov (United States)

    The development of selective breeding strategies employing marker assisted selection in species with low to medium density genetic maps must account for the non-random association of alleles between linked loci. To conduct efficient association studies and estimate the average size of haplotypes ge...

  7. [Only 1 out of 1 000 patients with alcohol dependence problems are reported according to the Driver's Licence Act. Physicians estimate to increase the number of reports some 70 times with a two-year ignition interlock program].

    Science.gov (United States)

    Bjerre, Bo; Heed, Birgitta; Kers, Sarah

    2004-05-13

    This poll, aimed at general practitioners and dependence specialists, shows that only one out of 1,000 patients diagnosed alcohol-dependent are reported to the county administrative board in accordance with the Swedish Driver's Licence Act. The anticipated negative effect on continued doctor-patient contact stands out as the predominant obstacle to filing a report. Among general practitioners an uncertainty about diagnosing alcohol dependence and alcohol abuse also was an important obstacle. Given the opportunity to participate in a two-year alcolock programme as an alternative to driver's licence revocation, doctors estimate that they would report some 70 times the number of patients. This estimation is obviously subject to considerable uncertainty, but does reflect an important attitude and an expectation that such a report constitutes a positive move from both an individual and a social perspective. PMID:15190769

  8. THE Z SPECIFICATION DEPENDENCE GRAPH

    Institute of Scientific and Technical Information of China (English)

    Wu Fangjun; Yi Tong

    2005-01-01

    The lack of existing solutions makes it really hard to understand formal specification languages since the application domain for representations is useful for the purpose of carrying out certain software engineering operations such as slicing and the computation of program metrics.A Z specification dependence graph is presented in this letter. It draws on the strengths of a range of earlier works and adapts them, if necessary, to the Z language.

  9. Dependent personality disorder

    Science.gov (United States)

    Dependent personality disorder is a mental condition in which people depend too much on others to meet their emotional ... Causes of dependent personality disorder are unknown. The disorder usually ... It is one of the most common personality disorders and ...

  10. Dependency, Empathy, and Altruism.

    Science.gov (United States)

    Miller, Shirley Matile

    This study examined the relationship of dependency, empathy, and altruism. It was hypothesized that: (1) dependency would be related in a curvilinear manner to empathy, with children who are moderate in dependency scoring highest in empathy; (2) dependency would be positively related to visible altruism when such prosocial behavior results in…

  11. Web Application Comprehension Based on Dependence Analysis

    Institute of Scientific and Technical Information of China (English)

    WU Jun-hua; XU Bao-wen; JIANG Ji-xiang

    2004-01-01

    Many research indicate a lot of money and time are spent on maintaining and modifying program delivered.So the policies to support program comprehension are very important.Program comprehension is a crucial and difficult task.Insufficient design, illogical code structure, short documents will enhance the comprehensive difficulty.Developing Web application is usually a process with quick implementation and delivery.In addition, generally a Web application is coded by combining mark language statements with some embedded applets.Such programming mode affects comprehension of Web applications disadvantageously.This paper proposes a method to improving understanding Web by dependence analysis and slice technology.

  12. Program specialization

    CERN Document Server

    Marlet, Renaud

    2013-01-01

    This book presents the principles and techniques of program specialization - a general method to make programs faster (and possibly smaller) when some inputs can be known in advance. As an illustration, it describes the architecture of Tempo, an offline program specializer for C that can also specialize code at runtime, and provides figures for concrete applications in various domains. Technical details address issues related to program analysis precision, value reification, incomplete program specialization, strategies to exploit specialized program, incremental specialization, and data speci

  13. Inexact Programming

    OpenAIRE

    Mahmood, Muhammad Yasir

    2012-01-01

    Two types of fuzzy linear programming i.e. fuzzy number linear programming and interval number linear programming are used for optimization problems. In interval form of linear programming we convert the inequalities from the feasible region, containing intervals as coefficients, to two groups of inequalities characterized by real, exact coefficients values. Then classical programming has been used to achieve an optimal solution in the feasible region. In fuzzy number linear programming, α‐cu...

  14. Sherman Creek Hatchery; Washington Department of Fish and Wildlife Fish Program, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Combs, Mitch (Washington Department of Fish and Wildlife, Kettle Falls, WA)

    2002-01-01

    Sherman Creek Hatchery's primary objective is the restoration and enhancement of the recreational and subsistence fishery in Lake Roosevelt and Banks Lake. The Sherman Creek Hatchery (SCH) was designed to rear 1.7 million kokanee fry for acclimation and imprinting during the spring and early summer. Additionally, it was designed to trap all available returning adult kokanee during the fall for broodstock operations and evaluations. Since the start of this program, the operations on Lake Roosevelt have been modified to better achieve program goals. The Washington Department of Fish and Wildlife, Spokane Tribe of Indians and the Colville Confederated Tribe form the interagency Lake Roosevelt Hatcheries Coordination Team (LRHCT) which sets goals and objectives for both Sherman Creek and the Spokane Tribal Hatchery and serves to coordinate enhancement efforts on Lake Roosevelt and Banks Lake. The primary changes have been to replace the kokanee fingerling program with a yearling (post smolt) program of up to 1,000,000 fish. To construct and operate twenty net pens to handle the increased production. The second significant change was to rear up to 300,000 rainbow trout fingerling at SCH from July through October, for stocking into the volunteer net pens. This enables the Spokane Tribal Hatchery (STH) to rear additional kokanee to further the enhancement efforts on Lake Roosevelt. Current objectives include increased use of native/indigenous stocks where available for propagation into Upper Columbia River Basin Waters. Monitoring and evaluation is preformed by the Lake Roosevelt Fisheries Monitoring Program. From 1988 to 1998, the principle sport fishery on Lake Roosevelt has shifted from walleye to include rainbow trout and kokanee salmon (Underwood et al. 1997, Tilson and Scholz 1997). The angler use, harvest rates for rainbow and kokanee and the economic value of the fishery has increased substantially during this 10-year period. The most recent information from

  15. Sherman Creek Hatchery; Washington Department of Fish and Wildlife Fish Program; 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Combs, Mitch (Washington Department of Fish and Wildlife, Kettle Falls, WA)

    2003-01-01

    Sherman Creek Hatchery's primary objective is the restoration and enhancement of the recreational and subsistence fishery in Lake Roosevelt and Banks Lake. The Sherman Creek Hatchery (SCH) was designed to rear 1.7 million kokanee fry for acclimation and imprinting during the spring and early summer. Additionally, it was designed to trap all available returning adult kokanee during the fall for broodstock operations and evaluations. Since the start of this program, the operations on Lake Roosevelt have been modified to better achieve program goals. The Washington Department of Fish and Wildlife, Spokane Tribe of Indians and the Colville Confederated Tribe form the interagency Lake Roosevelt Hatcheries Coordination Team (LRHCT) which sets goals and objectives for both Sherman Creek and the Spokane Tribal Hatchery and serves to coordinate enhancement efforts on Lake Roosevelt and Banks Lake. The primary changes have been to replace the kokanee fingerling program with a yearling (post smolt) program of up to 1,000,000 fish. To construct and operate twenty net pens to handle the increased production. The second significant change was to rear up to 300,000 rainbow trout fingerling at SCH from July through October, for stocking into the volunteer net pens. This enables the Spokane Tribal Hatchery (STH) to rear additional kokanee to further the enhancement efforts on Lake Roosevelt. Current objectives include increased use of native/indigenous stocks where available for propagation into Upper Columbia River Basin Waters. The Lake Roosevelt Fisheries Evaluation Program (LRFEP) is responsible for monitoring and evaluation on the Lake Roosevelt Projects. From 1988 to 1998, the principal sport fishery on Lake Roosevelt has shifted from walleye to include rainbow trout and kokanee salmon (Underwood et al. 1997, Tilson and Scholz 1997). The angler use, harvest rates for rainbow and kokanee and the economic value of the fishery has increased substantially during this 10-year

  16. Diseño de un Programa Computacional para Evaluar la Gestión de Mantenimiento Basado en la Seguridad de Funcionamiento Design of a Computational Program to Evaluate Maintenance Management based on Dependability

    Directory of Open Access Journals (Sweden)

    F. Espinosa

    2004-01-01

    Full Text Available Se ha definido una serie de índices y su implementación computacional, que permitan medir y explicar el valor de la eficiencia global de un sistema productivo en el cual se aplica la Seguridad de Funcionamiento (SdF. Estos índices corresponden a aspectos inherentes a la SdF, como ser confiabilidad, seguridad, mantenibilidad y disponibilidad, los cuales entregan los llamados Índices Directos. El conjunto de índices provenientes del proceso productivo, tales como calidad del producto, ciclo de tiempo de las operaciones y costos involucrados, estos últimos llamados Índices Complementarios. En la formulación de estos índices se integran datos de pérdidas de tiempo, producto de acciones o causas no deseadas y que perjudican al proceso productivo. Se da una definición alternativa para cada uno de los índices ya mencionados y entregando cada uno de ellos una información más relevante para el encargado del mantenimiento de la empresa.A series of indicators have been defined, as well as their computacional implementation, which allow to measure the efficency and to define a value of the overall efficiency of a productive system to which the concept of Dependability is applied. The indicators which represent inherent aspects of Dependability including reliability, safety, maintainability, and availability are named Direct Indicators. The set of productive process indicators, including quality of the product, time cycle involved in operations, and costs, are named Complementary Indicators. In the formulation of these indicators, data on losses of time are integrated,which represent the results of actions or unwanted causes, and which harm the productive process. An alternative definition for each of the indicators mentioned above is given, and each of them isprovided with more relevant information for the person in charge of the company maintenance.

  17. Programs To Aid FORTRAN Programming

    Science.gov (United States)

    Ragosta, Arthur E.

    1987-01-01

    Program-development time decreased while program quality increased. FORTRAN Programming Tools are series of programming tools used to support development and maintenance of FORTRAN 77 source codes. Included are debugging aid, central-processing-unit time-monitoring program, source-code maintenance aids, print utilities, and library of useful, well-documented programs. Tools assist in reducing development time and encouraging high-quality programming. Although intended primarily for FORTRAN programmers, some tools used on data files and other programming languages. Written in FORTRAN 77.

  18. Production data - Snake River sockeye salmon captive propagation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gene rescue captive broodstock program was established for ESA-listed endangered Snake River sockeye salmon from Redfish Lake, Idaho. The program has consisted of...

  19. Growth data - Snake River sockeye salmon captive propagation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gene rescue captive broodstock program was established for ESA-listed endangered Snake River sockeye salmon from Redfish Lake, Idaho. The program has consisted of...

  20. Broodyear data - Snake River sockeye salmon captive propagation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gene rescue captive broodstock program was established for ESA-listed endangered Snake River sockeye salmon from Redfish Lake, Idaho. The program has consisted of...

  1. Fish Culture data - Snake River sockeye salmon captive propagation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gene rescue captive broodstock program was established for ESA-listed endangered Snake River sockeye salmon from Redfish Lake, Idaho. The program has consisted of...

  2. Spawning data - Snake River sockeye salmon captive propagation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gene rescue captive broodstock program was established for ESA-listed endangered Snake River sockeye salmon from Redfish Lake, Idaho. The program has consisted of...

  3. Sherman Creek Hatchery; Washington Department of Fish and Wildlife Fish Program, 2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Lovrak, Jon (Washington Department of Fish and Wildlife, Fish Management Program, Hatcheries Division, Ford, WA); Combs, Mitch (Washington Department of Fish and Wildlife, Fish Management Program, Hatcheries Division, Kettle Falls, WA)

    2004-01-01

    Sherman Creek Hatchery's primary objective is the restoration and enhancement of the recreational and subsistence fishery in Lake Roosevelt and Banks Lake. The Sherman Creek Hatchery (SCH) was designed to rear 1.7 million kokanee fry for acclimation and imprinting during the spring and early summer. Additionally, it was designed to trap all available returning adult kokanee during the fall for broodstock operation and evaluation. Since the start of this program, the operations on Lake Roosevelt have been modified to better achieve program goals. The Washington Department of Fish and Wildlife, Spokane Tribe of Indians and the Colville Confederated Tribes form the interagency Lake Roosevelt Hatcheries Coordination Team (LRHCT) which sets goals and objectives for both Sherman Creek and the Spokane Tribal Hatchery. The LRHCT also serves to coordinate enhancement efforts on Lake Roosevelt and Banks Lake. Since 1994 the kokanee fingerling program has changed to yearling releases. By utilizing both the hatcheries and additional net pens, up to 1,000,000 kokanee yearlings can be reared and released. The construction and operation of twenty net pens in 2001 enabled the increased production. Another significant change has been to rear up to 300,000 rainbow trout fingerling at SCH from July through October, for stocking into the volunteer net pens. This enables the Spokane Tribal Hatchery (STH) to rear additional kokanee to further the enhancement efforts on Lake Roosevelt. Current objectives include increased use of native tributary stocks where available for propagation into Upper Columbia River Basin waters. The Lake Roosevelt Fisheries Evaluation Program (LRFEP) is responsible for monitoring and evaluation on the Lake Roosevelt Projects. From 1988 to 1998, the principal sport fishery on Lake Roosevelt has shifted from walleye to include rainbow trout and kokanee salmon (Underwood et al. 1997, Tilson and Scholz 1997). The angler use, harvest rates for rainbow and

  4. Practical Reflection and Metaprogramming for Dependent Types

    DEFF Research Database (Denmark)

    Christiansen, David Raymond

    2016-01-01

    program in these embedded languages. Interpreters and compilers must always take these invariants into account at each stage, and authors of embedded languages must work hard to relieve users of the burden of proving these properties. Idris is a dependently typed functional programming language whose...... semantics are given by elaboration to a core dependent type theory through a tactic language. This dissertation introduces elaborator reflection, in which the core operators of the elaborator are realized as a type of computations that are executed during the elaboration process of Idris itself, along with...

  5. Extremal dependence: some contributions

    CERN Document Server

    Ferreira, Helena

    2011-01-01

    Due to globalization and relaxed market regulation, we have assisted to an increasing of extremal dependence in international markets. As a consequence, several measures of tail dependence have been stated in literature in recent years, based on multivariate extreme-value theory. In this paper we present a tail dependence function and an extremal coefficient of dependence between two random vectors that extend existing ones. We shall see that in weakening the usual required dependence allows to assess the amount of dependence in $d$-variate random vectors based on bidimensional techniques. Very simple estimators will be stated and can be applied to the well-known \\emph{stable tail dependence function}. Asymptotic normality and strong consistency will be derived too. An application to financial markets will be presented at the end.

  6. Sensory processing disorders among substance dependents

    OpenAIRE

    Batya Engel-Yeger

    2014-01-01

    Purpose: (1) To compare sensory processing patterns as expressed in daily life between substance dependents and typical controls; (2) profile the prevalence of sensory processing disorders (SPD) among substance dependents; and (3) examine gender effect on SPD within and between groups. Methods: Two hundred ninety people aged 19-64 participated in this study. The study group included 145 individuals who lived in the community or took part in an outpatient program because of addiction to dru...

  7. Object-oriented Programming Laws for Annotated Java Programs

    OpenAIRE

    Gabriel Falconieri Freitas; Márcio Cornélio; Tiago Massoni; Rohit Gheyi

    2010-01-01

    Object-oriented programming laws have been proposed in the context of languages that are not combined with a behavioral interface specification language (BISL). The strong dependence between source-code and interface specifications may cause a number of difficulties when transforming programs. In this paper we introduce a set of programming laws for object-oriented languages like Java combined with the Java Modeling Language (JML). The set of laws deals with object-oriented features taking in...

  8. Removing Cycles in Esterel Programs

    Directory of Open Access Journals (Sweden)

    Reinhard von Hanxleden

    2007-05-01

    Full Text Available Esterel belongs to the family of synchronous programming languages, which are affected by cyclic signal dependencies. This prohibits a static scheduling, limiting the choice of available compilation techniques for programs with such cycles. This work proposes an algorithm that, given a constructive synchronous Esterel program, performs a semantics-preserving source code level transformation that removes cyclic signal dependencies. The transformation is divided into two parts: detection of cycles and iterative resolution of these cycles. It is based on the replacement of cycle signals by a signal expression involving no other cycle signals, thereby breaking the cycle. This transformation of cyclic Esterel programs enables the use of efficient compilation techniques, which are only available for acyclic programs. Furthermore, experiments indicate that the code transformation can even improve code quality produced by compilers that can already handle cyclic programs.

  9. Quasiconvex Programming

    OpenAIRE

    Eppstein, David

    2004-01-01

    We define quasiconvex programming, a form of generalized linear programming in which one seeks the point minimizing the pointwise maximum of a collection of quasiconvex functions. We survey algorithms for solving quasiconvex programs either numerically or via generalizations of the dual simplex method from linear programming, and describe varied applications of this geometric optimization technique in meshing, scientific computation, information visualization, automated algorithm analysis, an...

  10. Guide of dependability

    International Nuclear Information System (INIS)

    The raising of computerized control systems leads to study how they behave in fault configurations, even if the fault comes from an operator or from man-machine communication. This manual is divided into three parts: dependability basic concepts, theoretical tools for dependable systems, practical method for performing a dependable system. A 20 pages glossary and a French-English dictionary are included. (D.L.). 580 refs

  11. Systems dependability assessment

    CERN Document Server

    Aubry, Jean-François

    2015-01-01

    Presents recent developments of probabilistic assessment of systems dependability based on stochastic models, including graph theory, finite state automaton and language theory, for both dynamic and hybrid contexts.

  12. US oil dependency and energy security

    International Nuclear Information System (INIS)

    The three papers of this document were written in the framework of a seminar organized the 30 may 2002 by the IFRI in the framework of its program Energy and Climatic Change. The first presentation deals with the american oil policy since 1980 (relation between the oil dependence and the energy security, the Reagan oil policy, the new oil policy facing the increase of the dependence). The second one deals with the US energy security (oil security, domestic energy security, policy implications). The last presentation is devoted to the US oil dependence in a global context and the problems and policies of international energy security. (A.L.B.)

  13. Adam Smith and dependency.

    Science.gov (United States)

    Ozler, Sule

    2012-06-01

    The focus of this paper is the works and life of Adam Smith, who is widely recognized as the father and founder of contemporary economics. Latent content analysis is applied to his seminal text in economics, An Inquiry into the Nature and Causes of the Wealth of Nations (1776). The results reveal that Smith considers dependence on others a problem and sees the solution to this problem in impersonalized interdependence. In addition, his views on social dependency and personal dependency, reflected in his Lectures on Jurisprudence (1963) and The Theory of Moral Sentiments (1759), are analyzed. This analysis suggests a central tension between dependence and independence in Smith's writings. The personal dependency patterns he exhibited in his life, which also suggest a tension between dependence and independence, are identified through a reading of his biographies. Based on insights from psychoanalytic literature, this paper proposes that developing the ideas in the Wealth of Nations was part of Smith's creative solution to this tension. In particular, his solution to one individual's dependence on another was through a system of impersonalized interdependence. In other words, Smith defended against his personal dependence through his economic theorizing. PMID:22712591

  14. Dependence and Independence

    OpenAIRE

    Grädel, E.; Väänänen, J.

    2010-01-01

    We introduce an atomic formula intuitively saying that given variables are independent from given other variables if a third set of variables is kept constant. We contrast this with dependence logic. We show that our independence atom gives rise to a natural logic capable of formalizing basic intuitions about independence and dependence.

  15. Dependent Probability Spaces

    Science.gov (United States)

    Edwards, William F.; Shiflett, Ray C.; Shultz, Harris

    2008-01-01

    The mathematical model used to describe independence between two events in probability has a non-intuitive consequence called dependent spaces. The paper begins with a very brief history of the development of probability, then defines dependent spaces, and reviews what is known about finite spaces with uniform probability. The study of finite…

  16. Gradle dependency management

    CERN Document Server

    Ikkink, Hubert Klein

    2015-01-01

    If you work on Java projects, use Gradle as a build automation tool, and you use dependencies in your project, this is the book for you. Additionally, if you want to deploy your project artifacts as dependencies for other developers using Gradle, you've found the right book.

  17. Software system dependability

    International Nuclear Information System (INIS)

    Development of software with very high dependability constraints to drive or monitor critical systems must comply with stringent and complex requirements, to ensure the dependability level achieved and to give confidence to the involved people (development team, verification team, customers, control or certification bodies, users and other stakeholders). (authors)

  18. Activity Therapy Services and Chemical Dependency Rehabilitation.

    Science.gov (United States)

    James, Mark R.; Townsley, Robin K.

    1989-01-01

    Discusses how music, occupational, and recreation therapies can contribute to comprehensive treatment programs for chemical dependency. Sees prime contribution of activity therapy as lying in nature of experiential education, applying insight gained in counseling sessions and discussion groups to practical real-life situations. (Author/NB)

  19. Weakly dependent functional data

    CERN Document Server

    Hörmann, Siegfried; 10.1214/09-AOS768

    2010-01-01

    Functional data often arise from measurements on fine time grids and are obtained by separating an almost continuous time record into natural consecutive intervals, for example, days. The functions thus obtained form a functional time series, and the central issue in the analysis of such data consists in taking into account the temporal dependence of these functional observations. Examples include daily curves of financial transaction data and daily patterns of geophysical and environmental data. For scalar and vector valued stochastic processes, a large number of dependence notions have been proposed, mostly involving mixing type distances between $\\sigma$-algebras. In time series analysis, measures of dependence based on moments have proven most useful (autocovariances and cumulants). We introduce a moment-based notion of dependence for functional time series which involves $m$-dependence. We show that it is applicable to linear as well as nonlinear functional time series. Then we investigate the impact of ...

  20. Impact of Aspect-Oriented Programming on the Quality of Novices’ Programs: A Comparative Study

    OpenAIRE

    Marija Katic; Ivica Boticki; Kresimir Fertalj

    2013-01-01

    Aspect-oriented programming has been introduced in order to increase the modularity of object-oriented programs and is claimed to improve software quality. Although there are various researches on this claim, the question to what extent aspect-oriented programming improves the quality of programs depending on a developer’s experience still remains. The purpose of this study is to investigate whether aspect-oriented programming used by novice programmers improves the quality of programs, in te...

  1. Guarded dependent type theory with coinductive types

    DEFF Research Database (Denmark)

    Bizjak, Aleš; Grathwohl, Hans Bugge; Clouston, Ranald; Birkedal, Lars; Møgelberg, Rasmus Ejlers

    We present guarded dependent type theory, gDTT, an extensional dependent type theory with a later' modality and clock quantifiers for programming and proving with guarded recursive and coinductive types. The later modality is used to ensure the productivity of recursive definitions in a modular......, type based, way. Clock quantifiers are used for controlled elimination of the later modality and for encoding coinductive types using guarded recursive types. Key to the development of gDTT are novel type and term formers involving what we call delayed substitutions’. These generalise the applicative...... functor rules for the later modality considered in earlier work, and are crucial for programming and proving with dependent types. We show soundness of the type theory with respect to a denotational model....

  2. Atenção à dependência química na Universidade Federal do Espírito Santo: possibilidades da extensão universitária Atención a la dependencia química en la Universidad Federal del Espírito Santo: posibilidad de la extensión universitaria Substance dependence care at Federal University of Espírito Santo: program extension possibilities

    Directory of Open Access Journals (Sweden)

    Thiago Rodrigues de Amorim

    2007-12-01

    Full Text Available Objetiva-se neste trabalho descrever dois programas permanentes de extensão da Universidade Federal do Espírito Santo que atuam com base nos princípios de ensino, pesquisa, assistência e extensão, direcionados à temática das drogas: o Núcleo de Estudos sobre o Álcool e outras Drogas e o Programa de Atendimento ao Alcoolista do Hospital Universitário Cassiano Antônio Moraes. Tais estratégias constituem referências no Estado do Espírito Santo, promovendo a produção e divulgação de conhecimentos, a realização de pesquisas, a cooperação técnica e assessoria no campo da dependência química, a colaboração na organização de práticas de saúde que atendam às necessidades da população e a assistência ambulatorial para o tratamento do alcoolismo. Inicialmente descrevem-se o Programa de Atendimento ao Alcoolista e sua atuação interdisciplinar no atendimento a pacientes alcoolistas. Em seguida, são apresentadas a origem, a organização e as competências do Núcleo de Estudos sobre o Álcool e outras Drogas.El objetivo de este trabajo es describir dos programas permanentes de extensión de la Universidad Federal del Espírito Santo que actúan con base en los principios de la enseñanza, investigación, asistencia y extensión, en dirección al tema de las drogas: el Núcleo de Estudios sobre el Alcohol y otras Drogas y el Programa de Atención al Alcohólico del Hospital Universitario Cassiano Antônio Moraes. Dichas estrategias constituyen referencias en el Estado del Espírito Santo, promoviendo la producción y divulgación de conocimientos, la realización de investigaciones, la cooperación técnica y asesoría en el campo de la dependencia química, la colaboración en la organización de prácticas de salud que atiendan a las necesidades de la población y la asistencia en ambulatorio para el tratamiento del alcoholismo. Primeramente se describe el Programa de Atención al Alcohólico y su actuaci

  3. Financing Old Age Dependency

    OpenAIRE

    Shinichi Nishiyama; Kent Smetters

    2014-01-01

    Baby boomers are now retiring in large numbers, and most do not have enough assets of their own to finance retirement. Social insurance programs help baby boomers afford retirement, but these programs are substantially underfunded. Reforming these institutions earlier will produce fewer distortions than continued delays. Several options also exist for helping households prepare for their own retirement: improving financial literacy, more opt-out defaults, better guidance about the value of de...

  4. Effective Programming

    DEFF Research Database (Denmark)

    Frost, Jacob

    To investigate the use of VTLoE as a basis for formal derivation of functional programs with effects. As a part of the process, a number of issues central to effective formal programming are considered. In particular it is considered how to develop a proof system suitable for pratical reasoning......, how to implement this system in the generic proof assistant Isabelle and finally how to apply the logic and the implementation to programming....

  5. Program Fullerene

    DEFF Research Database (Denmark)

    Wirz, Lukas; Peter, Schwerdtfeger,; Avery, James Emil

    2013-01-01

    Fullerene (Version 4.4), is a general purpose open-source program that can generate any fullerene isomer, perform topological and graph theoretical analysis, as well as calculate a number of physical and chemical properties. The program creates symmetric planar drawings of the fullerene graph......-Fowler, and Brinkmann-Fowler vertex insertions. The program is written in standard Fortran and C++, and can easily be installed on a Linux or UNIX environment....

  6. Programming F#

    CERN Document Server

    Smith, Chris

    2009-01-01

    Why learn F#? This multi-paradigm language not only offers you an enormous productivity boost through functional programming, it also lets you develop applications using your existing object-oriented and imperative programming skills. With Programming F#, you'll quickly discover the many advantages of Microsoft's new language, which includes access to all the great tools and libraries of the .NET platform. Learn how to reap the benefits of functional programming for your next project -- whether it's quantitative computing, large-scale data exploration, or even a pursuit of your own. With th

  7. Programming Interactivity

    CERN Document Server

    Noble, Joshua

    2009-01-01

    Make cool stuff. If you're a designer or artist without a lot of programming experience, this book will teach you to work with 2D and 3D graphics, sound, physical interaction, and electronic circuitry to create all sorts of interesting and compelling experiences -- online and off. Programming Interactivity explains programming and electrical engineering basics, and introduces three freely available tools created specifically for artists and designers: Processing, a Java-based programming language and environment for building projects on the desktop, Web, or mobile phonesArduino, a system t

  8. Security of Dependable Systems

    DEFF Research Database (Denmark)

    Ahmed, Naveed; Jensen, Christian D.

    2011-01-01

    Security and dependability are crucial for designing trustworthy systems. The approach “security as an add-on” is not satisfactory, yet the integration of security in the development process is still an open problem. Especially, a common framework for specifying dependability and security is very...... much needed. There are many pressing challenges however; here, we address some of them. Firstly, security for dependable systems is a broad concept and traditional view of security, e.g., in terms of confidentiality, integrity and availability, does not suffice. Secondly, a clear definition of security...... in the dependability context is not agreed upon. Thirdly, security attacks cannot be modeled as a stochastic process, because the adversary’s strategy is often carefully planned. In this chapter, we explore these challenges and provide some directions toward their solutions....

  9. Security of Dependable Systems

    DEFF Research Database (Denmark)

    Ahmed, Naveed; Jensen, Christian D.

    Security and dependability are crucial for designing trustworthy systems. The approach “security as an add-on” is not satisfactory, yet the integration of security in the development process is still an open problem. Especially, a common framework for specifying dependability and security is very...... much needed. There are many pressing challenges however; here, we address some of them. Firstly, security for dependable systems is a broad concept and traditional view of security, e.g., in terms of confidentiality, integrity and availability, does not suffice. Secondly, a clear definition of security...... in the dependability context is not agreed upon. Thirdly, security attacks cannot be modeled as a stochastic process, because the adversary’s strategy is often carefully planned. In this chapter, we explore these challenges and provide some directions toward their solutions....

  10. Dependence for functional data

    OpenAIRE

    Valencia García, Dalia Jazmín

    2014-01-01

    Measuring dependence is a basic question when dealing with functional observations. It is of great interest to know the effect that one or more functional variables can have on other ones, and even predict values of one variable from another. Although, in the functional context, this theory has not been as extensively studied,some techniques to measure dependence in functional data have already been implemented, providing a single value which represents the degree of relation between the sets...

  11. Saving, dependency and development.

    Science.gov (United States)

    Kelley, A C; Schmidt, R M

    1996-01-01

    This study examines the impact of dependency on savings between 65 less developed countries (LDCs) and 23 developed countries over time and cross-sectionally since 1960. The study tests a modified Leff model and the Mason life-cycle framework. Empirical estimates address potential simultaneity between savings and output growth. The price indices of Summers and Heston are used because each country's national accounts are converted from nominal into purchasing-power variables. This eliminates the problems with using exchange rates which vary systematically by level of development with a "true" index of purchasing power. Savings (S/Y) is the percentage share of gross national saving in gross domestic product. Ygr is the growth of per capita income. Y/N gr is the growth in the per capita gross domestic product. Analysis is based on ordinary least squares (OLS) and two-stage least squares techniques, treatment for heteroscedascity, aggregation periods, several definitions of savings, different country samples, and aged dependency and youth dependency. Findings support the Mason variable-growth life-cycle framework that shows that changes in demographic factors accounted for a large part of savings. The relationships in the modified Leff-type model were weak, with the exception of the mildly negative youth and elderly dependency impact in the 1980s. The rate of growth of youth dependency was negative and significant in all cross-sections for the full sample, all panel estimates for both LDCs and the full sample, and in the 1980s for LDCs. In the OLS model, life-cycle effects were weaker, but direct dependency effects were stronger. S/Y over time became slightly more sensitive to changes in life cycle impacts but less sensitive to youth dependency. Demography's impact on savings over time is attributed to the increase in the pace of youth dependency decline and secondarily to its increasing sensitivity to life-cycle effects. PMID:12292225

  12. The Randomized Dependence Coefficient

    OpenAIRE

    Lopez-Paz, David; Hennig, Philipp; Schölkopf, Bernhard

    2013-01-01

    We introduce the Randomized Dependence Coefficient (RDC), a measure of non-linear dependence between random variables of arbitrary dimension based on the Hirschfeld-Gebelein-R\\'enyi Maximum Correlation Coefficient. RDC is defined in terms of correlation of random non-linear copula projections; it is invariant with respect to marginal distribution transformations, has low computational cost and is easy to implement: just five lines of R code, included at the end of the paper.

  13. Apache Maven dependency management

    CERN Document Server

    Lalou, Jonathan

    2013-01-01

    An easy-to-follow, tutorial-based guide with chapters progressing from basic to advanced dependency management.If you are working with Java or Java EE projects and you want to take advantage of Maven dependency management, then this book is ideal for you. This book is also particularly useful if you are a developer or an architect. You should be well versed with Maven and its basic functionalities if you wish to get the most out of this book.

  14. Cicop program

    International Nuclear Information System (INIS)

    It is described the input data for using in the Cicop computer code in the Honeywell Bull computer of CNEN. It is a program to prepare microscopic cross section library in a proper format to be directly used by the Citation program from the Macroscopic cross section and isotope concentration. (Author)

  15. BASIC Programming.

    Science.gov (United States)

    Jennings, Carol Ann

    Designed for use by both secondary- and postsecondary-level business teachers, this curriculum guide consists of 10 units of instructional materials dealing with Beginners All-Purpose Symbol Instruction Code (BASIC) programing. Topics of the individual lessons are numbering BASIC programs and using the PRINT, END, and REM statements; system…

  16. Energy Scan program

    Directory of Open Access Journals (Sweden)

    Poniatowska Katarzyna M.

    2014-04-01

    Full Text Available Femtoscopy of two non-identical particles in heavy ion collisions enables one to study the space-time asymmetry in the particle's emission process. Theoretical studies based on EPOS model performed for collision energies from the Beam Energy Scan program in STAR allow us to investigate the dependence of source sizes and dynamics effects. Obtained information will enable us to predict the collective behaviour of femtoscopic particle's source.

  17. Choreographic Programming

    DEFF Research Database (Denmark)

    Montesi, Fabrizio

    , as they offer a concise view of the message flows enacted by a system. For this reason, in the last decade choreographies have been used in the development of programming languages, giving rise to a programming paradigm that in this dissertation we refer to as Choreographic Programming. Recent studies show...... endpoint described in a choreography can then be automatically generated, ensuring that such implementations are safe by construction. However, current formal models for choreographies do not deal with critical aspects of distributed programming, such as asynchrony, mobility, modularity, and multiparty...... sessions; it remains thus unclear whether choreographies can still guarantee safety when dealing with such nontrivial features. This PhD dissertation argues for the suitability of choreographic programming as a paradigm for the development of safe distributed systems. We proceed by investigating its...

  18. A Review Paper on Microprocessor Based Controller Programming

    OpenAIRE

    Dilawari, Jaswinder Singh; Sandhu, Gurpreet Singh

    2012-01-01

    Designing of microprocessor based controllers requires specific hardware as well as software programming. Programming depends upon type of the software whether operating software or application software. Programming requires knowledge of system configuration and controller specific programming. Programs are always in digital form so microprocessor can control directly at digital level called Direct Digital Control (DDC).

  19. The genetics of nicotine dependence.

    Science.gov (United States)

    Li, Ming D

    2006-04-01

    Despite almost two decades of intensive tobacco-control efforts, approximately 23% of American adults continue to smoke, and 13% are nicotine-dependent. Cigarette smoking is the greatest preventable cause of cancer, accounting for at least 30% of all cancer deaths and 87% of lung cancer deaths. Smoking behavior is influenced by both genetic and environmental factors. Many years of twin and adoption studies have demonstrated that the heritability of liability for nicotine dependence (ND) is at least 50%. During the past several years, significant efforts have been made to identify susceptibility genes for ND using both genome-wide linkage and association analysis approaches. It is expected that identification of susceptibility genes for ND will allow the development and tailoring of both prevention strategies for individuals at risk and effective treatment programs and medicines for individuals who use tobacco products. This review summarizes the recent progress in genetic studies of ND. As genotyping technology is being improved and well-characterized clinical samples on smoking behavior become available, more and more genes and genetic variants responsible for ND will be identified in the near future. PMID:16539894

  20. Geothermal Loan Guaranty Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-11-17

    Presently the US imports a large proportion of its petroleum requirements. This dependence on foreign petroleum has had a major impact on our economy. As a result, the Federal government is sponsoring programs to offset this foreign reliance by conservation of oil and gas, conversion of petroleum using facilities to coal and nuclear energy and the development of alternate sources of energy. One of the most acceptable alternate resources is geothermal. It offers an environmentally sound energy resource, can be developed at reasonable cost in comparison to other forms of energy and has a long term production capacity. On September 3, 1974, the Geothermal Energy Research Development and Demonstration Act was enacted to further the research, development and demonstration of geothermal energy technologies. This Act also established the Geothermal Loan Guaranty Program to assist in the financing of geothermal resource development, both electrical and non-electrical. The highlights of that Guaranty Program are detailed in this report.

  1. Dependence modeling with copulas

    CERN Document Server

    Joe, Harry

    2014-01-01

    Dependence Modeling with Copulas covers the substantial advances that have taken place in the field during the last 15 years, including vine copula modeling of high-dimensional data. Vine copula models are constructed from a sequence of bivariate copulas. The book develops generalizations of vine copula models, including common and structured factor models that extend from the Gaussian assumption to copulas. It also discusses other multivariate constructions and parametric copula families that have different tail properties and presents extensive material on dependence and tail properties to a

  2. Programming Python

    CERN Document Server

    Lutz, Mark

    2011-01-01

    If you've mastered Python's fundamentals, you're ready to start using it to get real work done. Programming Python will show you how, with in-depth tutorials on the language's primary application domains: system administration, GUIs, and the Web. You'll also explore how Python is used in databases, networking, front-end scripting layers, text processing, and more. This book focuses on commonly used tools and libraries to give you a comprehensive understanding of Python's many roles in practical, real-world programming. You'll learn language syntax and programming techniques in a clear and co

  3. NORD program

    International Nuclear Information System (INIS)

    A procedure of estimating the state of the WWER-1000 core power density on the basic of the in-core instrumentation system data is presented. A NORD program realizing this procedure in BASIC has been developed for on-line processing of experimental data. The program is designed for operation in dialog mode, has a service input-output unit and a unit for statistical processing of experimental results. The program makes it possible to evaluate quantitatively the differences of the power density fields obtained on the basis of readings taken from temperature control detectors and detectors of the neutron measuring channels. 5 refs.; 3 tabs

  4. US oil dependency and energy security; Dependance petroliere et securite energetique americaine

    Energy Technology Data Exchange (ETDEWEB)

    Noel, P. [Institut francais des Relations Internationals, 75 - Paris (France)]|[Universite Pierre Mendes-France-IEPE-CNRS, 38 - Grenoble (France)

    2002-07-01

    The three papers of this document were written in the framework of a seminar organized the 30 may 2002 by the IFRI in the framework of its program Energy and Climatic Change. The first presentation deals with the american oil policy since 1980 (relation between the oil dependence and the energy security, the Reagan oil policy, the new oil policy facing the increase of the dependence). The second one deals with the US energy security (oil security, domestic energy security, policy implications). The last presentation is devoted to the US oil dependence in a global context and the problems and policies of international energy security. (A.L.B.)

  5. State Dependence in Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar

    2014-01-01

    This study examines the extent state dependence among unemployed immigrants in a dynamic discrete choice framework. Three alternative methodologies are employed to control for the problem of the initial condition. The empirical findings show that there is a considerable correlation between the un...

  6. Observer-dependent entanglement

    International Nuclear Information System (INIS)

    Understanding the observer-dependent nature of quantum entanglement has been a central question in relativistic quantum information. In this paper, we will review key results on relativistic entanglement in flat and curved spacetime and discuss recent work which shows that motion and gravity have observable effects on entanglement between localized systems. (paper)

  7. Observer dependent entanglement

    OpenAIRE

    Alsing, Paul M.; Fuentes, Ivette

    2012-01-01

    Understanding the observer-dependent nature of quantum entanglement has been a central question in relativistic quantum information. In this paper we will review key results on relativistic entanglement in flat and curved spacetime and discuss recent work which shows that motion and gravity have observable effects on entanglement between localized systems.

  8. Path dependence and creation

    DEFF Research Database (Denmark)

    Garud, Raghu; Karnøe, Peter

    the place of agency in these theories that take history so seriously. In the end, they are as interested in path creation and destruction as they are in path dependence. This book is compiled of both theoretical and empirical writing. It shows relatively well-known industries such as the automobile...

  9. Women and Drug Dependence.

    Science.gov (United States)

    Valentich, Mary

    1982-01-01

    Presents a feminist perspective which offers a social structural framework for examining women's problematic behavior in traditional gender roles. Examines implications for treatment of women with drug dependence problems including developing the helping agent's awareness of the pervasiveness of sexism and its potentially negative effects.…

  10. Program overview

    International Nuclear Information System (INIS)

    The program overview describes the following resources and facilities; laser facilities, main laser room, target room, energy storage, laboratory area, building support systems, general plant project, and the new trailer complex

  11. [Mentoring program].

    Science.gov (United States)

    Watanabe, N

    2001-11-01

    Due to drastic changes in the business environment and prolonged recession, stress management practices in business organizations have been encountering two kinds of problems: budget cuts and difficulties in the delivery of services. The feasibility of mentoring programs to cope with these two problems is discussed. Through an extensive review of the literature, it becomes clear that mentoring programs have the following features and advantages; (1) One to one relationship between elder mentor and younger protégé has a favorable effect on the both mentor and protégé's mental health. (2) Formal mentoring programs are widely used in the U.S. for the prevention of juvenile delinquency, professional education, and human resource development in business settings. (3) Mentoring programs, in general, are practiced with the cooperation of kindred volunteers and professionals who monitor the mentor-protégé relationships. (4) Since a mentoring program utilizes a wide range of human resources in work organizations, it is able to overcome the "budget and delivery" problems. Further discussions are about the comparison with listener programs as well as the relationship with the total human resource management system. PMID:11802451

  12. Decentralizing Eligibility for a Federal Antipoverty Program

    OpenAIRE

    Ravallion, Martin

    2009-01-01

    In theory, the informational advantage of decentralizing the eligibility criteria for a federal antipoverty program could come at a large cost to the program's performance in reaching the poor nationally. Whether this happens in practice depends on the size of the local-income effect on the eligibility cutoffs. China's Di Bao program provides a case study. Poorer municipalities adopt systematically lower thresholds—roughly negating intercity differences in need for the program and generating ...

  13. A Study on Meta-Programming Environments

    OpenAIRE

    Tenma, Takao

    1990-01-01

    In order to increase the productivity of software development, a programming environment which supports programming activities should be provided. Recently, an integrated programming environment which provides language-oriented facilities through an interactive user interface enables the higher level of productivity. However, an integrated environment should be constructed for each programming language. Since a development of a software strongly depends on the application domain, a langua...

  14. Activity Dependent Regulation of Inhibitory Circuitry

    OpenAIRE

    Sharma, Nikhil

    2015-01-01

    Inhibition controls information flow through a neural circuit by modulating synaptic integration, restricting action potentials, and coordinating the activity of ensembles of neurons. These functions are mediated by a diverse array of inhibitory neuron subtypes that synapse on defined domains of a postsynaptic neuron. Activity-dependent transcription controls inhibitory synapse number and function, but how this transcription program affects the inhibitory inputs that form on di...

  15. Intensity dependent spread theory

    Science.gov (United States)

    Holben, Richard

    1990-01-01

    The Intensity Dependent Spread (IDS) procedure is an image-processing technique based on a model of the processing which occurs in the human visual system. IDS processing is relevant to many aspects of machine vision and image processing. For quantum limited images, it produces an ideal trade-off between spatial resolution and noise averaging, performs edge enhancement thus requiring only mean-crossing detection for the subsequent extraction of scene edges, and yields edge responses whose amplitudes are independent of scene illumination, depending only upon the ratio of the reflectance on the two sides of the edge. These properties suggest that the IDS process may provide significant bandwidth reduction while losing only minimal scene information when used as a preprocessor at or near the image plane.

  16. State dependent choice

    OpenAIRE

    Manzini, Paola; Mariotti, Marco

    2015-01-01

    We propose a theory of choices that are influenced by the psychological state of the agent. The central hypothesis is that the psychological state controls the urgency of the attributes sought by the decision maker in the available alternatives. While state dependent choice is less restricted than rational choice, our model does have empirical content, expressed by simple ‘revealed preference’ type of constraints on observable choice data. We demonstrate the applicability of simple versions o...

  17. From PSAs to dependability

    International Nuclear Information System (INIS)

    Dependability is all the concepts (Reliability, Availability, Maintainability, and Safety) which are used to characterize the capabilities of a product to operate, to be repaired, and to not cause damage to objects or persons. PSAs (Probabilistic Safety Assessments) are a particular means of assessing the level of safety of hazardous installations. The purpose of this communication is to show that although it is still an emerging concept within EDF projects, the introduction of methods for taking account of dependability in design can be very useful at improving the safety of plants by, for example, establishing the link between operating feedback on one hand, and maintenance and operating policy on the other. Finally, we will extend our thinking on the insertion of dependability (and PSA) into design work to consideration of human factors in these projects. All too often kept apart, the technical and human aspects of design projects do have common characteristics: participation in safety and ease of operational of power plants, need for sufficiently early insertion in order to obtain pertinent result, etc. 8 figs

  18. The LANL Physical Inventory Program

    International Nuclear Information System (INIS)

    The LANL physical inventory program (statistically based) provides assurance that the inventory is represented to the defined confidence levels. In addition, it establishes a benchmark to prove that the inventory is accurately stated. The LANL's Physical Inventory Program for nuclear materials requires the performance of periodic physical inventories and special inventories of nuclear material. The Inventory Program also requires the reconciliation of inventory measurements with previously established nuclear material accountability values. This inventory program applies to all material balance areas (MBAs) and is designed in accordance with DOE order 474.1, 'Nuclear Material Control and Accountability'. The program uses a graded approach for performing physical inventories with primary emphasis placed on Categories I and II quantities of special nuclear material. This paper describes the essential elements of the LANL Physical Inventory Program. In addition, the inter-dependency of the Inventory Program with respect to other LANL MC and A Programs is discussed. This paper, by outlining the elements and approach of a site-specific physical inventory program assists safeguards practitioners in the design of related physical inventory programs.

  19. Object-oriented Programming Laws for Annotated Java Programs

    Directory of Open Access Journals (Sweden)

    Gabriel Falconieri Freitas

    2010-03-01

    Full Text Available Object-oriented programming laws have been proposed in the context of languages that are not combined with a behavioral interface specification language (BISL. The strong dependence between source-code and interface specifications may cause a number of difficulties when transforming programs. In this paper we introduce a set of programming laws for object-oriented languages like Java combined with the Java Modeling Language (JML. The set of laws deals with object-oriented features taking into account their specifications. Some laws deal only with features of the specification language. These laws constitute a set of small transformations for the development of more elaborate ones like refactorings.

  20. ELISE, a code for intensity dependent effects

    International Nuclear Information System (INIS)

    The Electron ring Limits on Intensity, Stability, and Emittance (ELISE) code described in this paper computes many of the intensity dependent effects of interest to the builder of a small electron storage ring. ELISE is a program, developed largely for the author's own use, which duplicates many of the functions provided by the more general program ZAP developed by the Berkeley group. The motivation for the code was to provide an interactive system for quick answers that could be used during accelerator commissioning. A lattice program, IDA, developed earlier by the author while at Brookhaven National Laboratory, provides a good model of the type of user friendly interaction that would be desirable in such a code

  1. Integer programming

    CERN Document Server

    Conforti, Michele; Zambelli, Giacomo

    2014-01-01

    This book is an elegant and rigorous presentation of integer programming, exposing the subject’s mathematical depth and broad applicability. Special attention is given to the theory behind the algorithms used in state-of-the-art solvers. An abundance of concrete examples and exercises of both theoretical and real-world interest explore the wide range of applications and ramifications of the theory. Each chapter is accompanied by an expertly informed guide to the literature and special topics, rounding out the reader’s understanding and serving as a gateway to deeper study. Key topics include: formulations polyhedral theory cutting planes decomposition enumeration semidefinite relaxations Written by renowned experts in integer programming and combinatorial optimization, Integer Programming is destined to become an essential text in the field.

  2. Programming Guidelines for FBD Programs in Reactor Protection System Software

    International Nuclear Information System (INIS)

    Properties of programming languages, such as reliability, traceability, etc., play important roles in software development to improve safety. Several researches are proposed guidelines about programming to increase the dependability of software which is developed for safety critical systems. Misra-c is a widely accepted programming guidelines for the C language especially in the sector of vehicle industry. NUREG/CR-6463 helps engineers in nuclear industry develop software in nuclear power plant systems more dependably. FBD (Function Block Diagram), which is one of programming languages defined in IEC 61131-3 standard, is often used for software development of PLC (programmable logic controllers) in nuclear power plants. Software development for critical systems using FBD needs strict guidelines, because FBD is a general language and has easily mistakable elements. There are researches about guidelines for IEC 61131-3 programming languages. They, however, do not specify details about how to use languages. This paper proposes new guidelines for the FBD based on NUREG/CR-6463. The paper introduces a CASE (Computer-Aided Software Engineering) tool to check FBD programs with the new guidelines and shows availability with a case study using a FBD program in a reactor protection system. The paper is organized as follows

  3. Programming Algol

    CERN Document Server

    Malcolme-Lawes, D J

    2014-01-01

    Programming - ALGOL describes the basics of computer programming using Algol. Commands that could be added to Algol and could increase its scope are described, including multiplication and division and the use of brackets. The idea of labeling or naming a command is also explained, along with a command allowing two alternative results. Most of the important features of Algol syntax are discussed, and examples of compound statements (that is, sets of commands enclosed by a begin ... end command) are given.Comprised of 11 chapters, this book begins with an introduction to the digital computer an

  4. Programming Interactivity

    CERN Document Server

    Noble, Joshua

    2012-01-01

    Ready to create rich interactive experiences with your artwork, designs, or prototypes? This is the ideal place to start. With this hands-on guide, you'll explore several themes in interactive art and design-including 3D graphics, sound, physical interaction, computer vision, and geolocation-and learn the basic programming and electronics concepts you need to implement them. No previous experience is necessary. You'll get a complete introduction to three free tools created specifically for artists and designers: the Processing programming language, the Arduino microcontroller, and the openFr

  5. Dependent Data in Economic and Financial Problems

    Czech Academy of Sciences Publication Activity Database

    Kaňková, Vlasta

    Vol. 1. Praha : Professional Publishing, Mikulova 1572/13, 149 00 Praha 4, Czech Republic, 2011 - (Dlouhý, M.; Skočdopolová, V.), s. 327-332 ISBN 978-80-7431-058-4. [29th International Conference Mathematical Methods in Economics 2011. Janská Dolina (SK), 06.09.2011-09.09.2011] R&D Projects: GA ČR GAP402/10/1610; GA ČR GAP402/11/0150; GA ČR GAP402/10/0956 Institutional research plan: CEZ:AV0Z10750506 Keywords : Stochastic programming * Wasserstein metric * L_1norm * Empirical estimates * One-stage problems * Multistage problems * Independent samples * m-dependent samples * Markov dependence * Phi-mixing random samples Subject RIV: BB - Applied Statistics, Operational Research http://library.utia.cas.cz/separaty/2011/E/kankova-dependent data in economic and financial problems.pdf

  6. Planning an outing from hospital for ventilator-dependent children.

    Science.gov (United States)

    Gilgoff, I S; Helgren, J

    1992-10-01

    Returning ventilator-dependent children to the home environment has become a well-accepted occurrence. The success of a home program depends on careful pre-discharge planning in order to ensure the child's medical safety, and adequate preparation to ensure the child's and family's adjustment to an active community life after discharge. To achieve this, involvement in community activities must begin while the child is still in hospital. As part of a complete rehabilitation program, nine ventilator-dependent children were taken on an inpatient outing to Disneyland. The planning and goals of the outing are described. PMID:1397730

  7. Portage and Path Dependence*

    Science.gov (United States)

    Bleakley, Hoyt; Lin, Jeffrey

    2012-01-01

    We examine portage sites in the U.S. South, Mid-Atlantic, and Midwest, including those on the fall line, a geomorphological feature in the southeastern U.S. marking the final rapids on rivers before the ocean. Historically, waterborne transport of goods required portage around the falls at these points, while some falls provided water power during early industrialization. These factors attracted commerce and manufacturing. Although these original advantages have long since been made obsolete, we document the continuing importance of these portage sites over time. We interpret these results as path dependence and contrast explanations based on sunk costs interacting with decreasing versus increasing returns to scale. PMID:23935217

  8. US Oil import dependency

    International Nuclear Information System (INIS)

    After declining oil imports in the US in the first half of the 1980's, the trend is reversed since 1986; the world oil price collapse of 1986 was obviously a major factor in the US import rise. However, it may just have expedited a trend that was already in the making rather than started a new. The growing import dependence have evident impacts on the balance of trade (but not so important), on encouraging domestic production against supply disruption for example, and on environmental policies

  9. Time Dependent Resonance Theory

    OpenAIRE

    Soffer, A.; Weinstein, M. I.

    1998-01-01

    An important class of resonance problems involves the study of perturbations of systems having embedded eigenvalues in their continuous spectrum. Problems with this mathematical structure arise in the study of many physical systems, e.g. the coupling of an atom or molecule to a photon-radiation field, and Auger states of the helium atom, as well as in spectral geometry and number theory. We present a dynamic (time-dependent) theory of such quantum resonances. The key hypotheses are (i) a reso...

  10. SLED program

    International Nuclear Information System (INIS)

    A FORTRAN program is described which, for a given cavity and timing, yields all fields as a (piecewise) function of time, and which, for any mix of SLEDded and non-SLEDded klystrons of any given energy/klystron, yields the SLED operation parameters. The note explains the input and output parameters as they appear in the code output. 3 figures, 19 tables

  11. ORGEL program

    Energy Technology Data Exchange (ETDEWEB)

    none

    1963-09-01

    Parameter optimization studies for an ORGEL power plant are reported, and the ESSOR test reactor used in the program is described. Research at Ispra in reactor physics, technology, metallurgy, heat transfer, chemistry, and physical chemistry associated with ORGEL development is also summarized. (D.C.W.)

  12. Variable Size Genetic Network Programming

    Science.gov (United States)

    Katagiri, Hironobu; Hirasawa, Kotaro; Hu, Jinglu; Murata, Junichi

    Genetic Network Programming (GNP) is a kind of volutionary methods, which evolves arbitrary directed graph programs. Previously, the program size of GNP was fixed. In the paper, a new method is proposed, where the program size is adaptively changed depending on the frequency of the use of nodes. To control and to decide a program size are important and difficult problems in Evolutionary Computation, especially, a well-known crossover operator tends to cause bloat. We introduce two additional operators, add operator and delete operator, that can change the number of each kind of nodes based on whether a node function is important in the environment or not. Simulation results shows that the proposed method brings about extremely better results compared with ordinary fixed size GNP.

  13. Velocity dependant splash behaviour

    Science.gov (United States)

    Hamlett, C. A. E.; Shirtcliffe, N. J.; McHale, G.; Ahn, S.; Doerr, S. H.; Bryant, R.; Newton, M. I.

    2012-04-01

    Extreme soil water repellency can occur in nature via condensation of volatile organic compounds released during wildfires and can lead to increased erosion rate. Such extreme water repellent soil can be classified as superhydrophobic and shares similar chemical and topographical features to specifically designed superhydrophobic surfaces. Previous studies using high speed videography to investigate single droplet impact behaviour on artificial superhydrophobic have revealed three distinct modes of splash behaviour (rebound, pinned and fragmentation) which are dependent on the impact velocity of the droplet. In our studies, using high-speed videography, we show that such splash behaviour can be replicated on fixed 'model' water repellent soils (hydrophobic glass beads/particles). We show that the type of splash behaviour is dependent on both the size and chemical nature of the fixed particles. The particle shape also influences the splash behaviour as shown by drop impact experiments on fixed sand samples. We have also studied soil samples, as collected from the field, which shows that the type of droplet splash behaviour can lead to enhanced soil particle transport.

  14. Program overview: Subsurface science program

    International Nuclear Information System (INIS)

    The OHER Subsurface Science Program is DOE's core basic research program concerned with subsoils and groundwater. These practices have resulted in contamination by mixtures of organic chemicals, inorganic chemicals, and radionuclides. A primary long-term goal is to provide a foundation of knowledge that will lead to the reduction of environmental risks and to cost-effective cleanup strategies. Since the Program was initiated in 1985, a substantial amount of research in hydrogeology, subsurface microbiology, and the geochemistry of organically complexed radionuclides has been completed, leading to a better understanding of contaminant transport in groundwater and to new insights into microbial distribution and function in the subsurface environments. The Subsurface Science Program focuses on achieving long-term scientific advances that will assist DOE in the following key areas: providing the scientific basis for innovative in situ remediation technologies that are based on a concept of decontamination through benign manipulation of natural systems; understanding the complex mechanisms and process interactions that occur in the subsurface; determining the influence of chemical and geochemical-microbial processes on co-contaminant mobility to reduce environmental risks; improving predictions of contaminant transport that draw on fundamental knowledge of contaminant behavior in the presence of physical and chemical heterogeneities to improve cleanup effectiveness and to predict environmental risks

  15. Constraint Programming versus Mathematical Programming

    DEFF Research Database (Denmark)

    Hansen, Jesper

    2003-01-01

    Constraint Logic Programming (CLP) is a relatively new technique from the 80's with origins in Computer Science and Artificial Intelligence. Lately, much research have been focused on ways of using CLP within the paradigm of Operations Research (OR) and vice versa. The purpose of this paper...

  16. Linear programming

    CERN Document Server

    Karloff, Howard

    1991-01-01

    To this reviewer’s knowledge, this is the first book accessible to the upper division undergraduate or beginning graduate student that surveys linear programming from the Simplex Method…via the Ellipsoid algorithm to Karmarkar’s algorithm. Moreover, its point of view is algorithmic and thus it provides both a history and a case history of work in complexity theory. The presentation is admirable; Karloff's style is informal (even humorous at times) without sacrificing anything necessary for understanding. Diagrams (including horizontal brackets that group terms) aid in providing clarity. The end-of-chapter notes are helpful...Recommended highly for acquisition, since it is not only a textbook, but can also be used for independent reading and study. —Choice Reviews The reader will be well served by reading the monograph from cover to cover. The author succeeds in providing a concise, readable, understandable introduction to modern linear programming. —Mathematics of Computing This is a textbook intend...

  17. Efficient Dependence Analysis for UML Statechart Diagrams and Its Applications

    Institute of Scientific and Technical Information of China (English)

    YITong; WUFangjun

    2005-01-01

    Dependence analysis is a well-known technique to analyze, understand and maintain programs,which has been widely used in activities of software engineering and reengineering. Although dependence analysis for programs written in high-level languages has been widely studied in literatures, very little work is involved in analyzing dependence for Unified modeling language(UML) models. Therefore, the paper proposes a new approach for analyzing dependences among UML statechart diagrams for three cases: (1) it does not contain composite states; (2) it may include ordinal substates; (3) it may include concurrent substates. Firstly, we analyze and compute data and control dependences in Case 1 and Case 2 at full length. Then, using the information obtained in the previous steps, we discuss concurrent dependence and synchronal dependence besides data and control dependencesin Case 3. Finally, we present one of the most important applications of dependence analysis - program slicing, using the method presented in this paper. Our method successfully solves the problems in previous methods, and can obtain more precise slices than any other methods we known.

  18. Biological programming

    OpenAIRE

    Ramsden, Jeremy J.; Bándi, Gergely

    2010-01-01

    Biology offers a tremendous set of concepts that are potentially very powerfully usable for the software engineer, but they have been barely exploited hitherto. In this position paper we propose a fresh attempt to create the building blocks of a programming technology that could be as successful as life. A key guiding principle is to develop and make use of unambiguous definitions of the essential features of life.

  19. Program summary

    International Nuclear Information System (INIS)

    The operating, construction, and development activities of the Department of Energy in the areas of uranium enrichment are described. The DOE supplies the enrichment service through toll enrichment contracts with foreign and domestic utilities by enriching uranium supplied by the utility to the desired U-235 level. This role will continue well into the next century. In addition it provides enriched uranium for US Government needs and for R and D purposes. At the present time, almost all the world's capacity to produce enriched uranium uses the gaseous diffusion process. The United States built the first gaseous diffusion plant during World War II. Later this plant was expanded and two additional plants were built. There is presently a $1.5 billion improvement and uprating program near completion which will improve the plant efficiency and increase the total capacity of the three plants by 60 percent to 27.3 million SWU per year. The Administration's energy message in 1977 provided for a further expansion of this capacity by using gas centrifuge technology. The new gas centrifuge plant is being built near the existing GDP near Portsmouth, Ohio. The normal capacity of an 8 building process plant will be 13.2 million SWU per year. The first 2.2 million SWU of capacity is scheduled to be available in 1989. The remaining capacity will be added as needed to meet demand and the overall goal of the program. The goal of the Uranium Enrichment Program is to meet domestic, foreign, and US Government requirements for uranium enrichment services in an economical, reliable, safe and environmentally acceptable manner. To ensure accomplishment of this goal, the overall program is broken down into three areas of implementation; Enrichment Operations; Capacity Upgrading Operations; and Business Operations

  20. Sensory processing disorders among substance dependents

    Directory of Open Access Journals (Sweden)

    Batya Engel-Yeger

    2014-08-01

    Full Text Available Purpose: (1 To compare sensory processing patterns as expressed in daily life between substance dependents and typical controls; (2 profile the prevalence of sensory processing disorders (SPD among substance dependents; and (3 examine gender effect on SPD within and between groups. Methods: Two hundred ninety people aged 19-64 participated in this study. The study group included 145 individuals who lived in the community or took part in an outpatient program because of addiction to drugs/alcohol and had been clean for over three months. The control group included 145 individuals who were not exposed to drugs or alcohol on a regular basis and did not suffer from addictive behavior. All participants filled a demographic questionnaire. Those who met the inclusion criteria completed the Adolescent/Adult Sensory Profile (AASP so that their sensory processing patterns could be assessed. Results: When comparing both groups, the study group showed greater sensory sensitivity and significantly higher prevalence of SPD. Significant group/gender interaction was found in regard to sensation seeking. Discussion: SPD among substance dependents may be expressed in daily life by either hypersensitivity or hyposensitivity. The behavioral outcomes reflected by the AASP support neurophysiological manifestations about SPD of substance dependents. The evaluation process of substance dependents should refer to their sensory processing abilities. In case SPD is diagnosed, Occupational Therapy and specific sensory–based interventions should be considered in order to fit the specific needs of individuals and enhance their performance, meaningful participation, and quality of life.

  1. DEPEND: A simulation-based environment for system level dependability analysis

    Science.gov (United States)

    Goswami, Kumar; Iyer, Ravishankar K.

    1992-01-01

    The design and evaluation of highly reliable computer systems is a complex issue. Designers mostly develop such systems based on prior knowledge and experience and occasionally from analytical evaluations of simplified designs. A simulation-based environment called DEPEND which is especially geared for the design and evaluation of fault-tolerant architectures is presented. DEPEND is unique in that it exploits the properties of object-oriented programming to provide a flexible framework with which a user can rapidly model and evaluate various fault-tolerant systems. The key features of the DEPEND environment are described, and its capabilities are illustrated with a detailed analysis of a real design. In particular, DEPEND is used to simulate the Unix based Tandem Integrity fault-tolerance and evaluate how well it handles near-coincident errors caused by correlated and latent faults. Issues such as memory scrubbing, re-integration policies, and workload dependent repair times which affect how the system handles near-coincident errors are also evaluated. Issues such as the method used by DEPEND to simulate error latency and the time acceleration technique that provides enormous simulation speed up are also discussed. Unlike any other simulation-based dependability studies, the use of these approaches and the accuracy of the simulation model are validated by comparing the results of the simulations, with measurements obtained from fault injection experiments conducted on a production Tandem Integrity machine.

  2. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Standards News Cancer Cancer Programs Cancer Programs American Joint Committee on Cancer Cancer Advocacy Efforts Cancer Liaison ... Validation Programs Accredited Education Institutes CME Accreditation CME Joint Providership Program Program for Validation and Verification of ...

  3. Phenomenology dependent timescales

    International Nuclear Information System (INIS)

    monitoring/observation program. (authors)

  4. Dynamic Slicing of Object-Oriented Programs

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Program slice has many applications such as program debugging,testing, maintena n ce, and complexity measurement. A static slice consists of all statements in pro gram P that may effect the value of variable v at some point p, and a dynamic s lice consists only of statements that influence the value of variable occurrence for specific program inputs. In this paper, we concern the problem of dynamic s licing of object-oriented programs which, to our knowledge, has not been addres s ed in the literatures. To solve this problem, we present the dynamic object-ori e nted dependence graph (DODG)which is an arc-classified digraph to explicitly re p resent various dynamic dependence between statement instances for a particular e xecution of an object-oriented program. Based on the DODG, we present a two-ph as e backward algorithm for computing a dynamic slice of an object-oriented program.

  5. Programming Pig

    CERN Document Server

    Gates, Alan

    2011-01-01

    This guide is an ideal learning tool and reference for Apache Pig, the open source engine for executing parallel data flows on Hadoop. With Pig, you can batch-process data without having to create a full-fledged application-making it easy for you to experiment with new datasets. Programming Pig introduces new users to Pig, and provides experienced users with comprehensive coverage on key features such as the Pig Latin scripting language, the Grunt shell, and User Defined Functions (UDFs) for extending Pig. If you need to analyze terabytes of data, this book shows you how to do it efficiently

  6. RADARSAT program

    Science.gov (United States)

    Mcnally, J.; Parashar, S.

    1993-01-01

    Work on the RADARSAT system is progressing towards the currently scheduled launch date of early 1995. The spacecraft bus and the Synthetic Aperture Radar (SAR) payload are at various stages of development. Requirements for the ground segment have been mostly established. The design of the ground elements such as the mission control facility and the SAR data processor is underway. The SAR applications development work is continuing and the chosen distributor, RADARSAT International Inc. (RSI) is making preparations to market RADARSAT data internationally. A plan for the follow-on to RADARSAT 1 is being finalized to ensure continuity of SAR data under the Radarsat program.

  7. Programming Razor

    CERN Document Server

    Chadwick, Jess

    2011-01-01

    Take Razor for a test drive and discover first hand how this scripting syntax simplifies the way you create dynamic, data-driven websites. With this concise guide, you'll work with Razor syntax by building example websites with Microsoft WebMatrix and ASP.NET MVC. You'll quickly learn how Razor lets you combine code and content in a fluid and expressive manner on Windows-based servers. Programming Razor also explores components of the Razor API, and shows you how Razor templates are turned into rendered HTML. By the end of this book, you'll be able to create Razor-based websites with custom

  8. A novel formal approach to program slicing

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Program slicing is a well-known program analysis technique that extracts the elements of a program related to a particular computation. The current slicing methods, however, are singular (mainly based on a program or system dependence graph), and lack good reusability and flexibility. In this paper, we present a novel formal method for program slicing, modular monadic program slicing, which abstracts the computation of program slicing as a slice monad transformer, and applies it to semantic descriptions of the program analyzed in a modular way, forming the corresponding monadic slicing algorithms. The modular abstraction mechanism allows our slicing method to possess excellent modularity and language-flexibility properties. We also give the related axioms of our slice monad transformer, the proof of the correctness and the implementation of monadic slicing algorithms. We reveal the relations of our algorithms and graph-reachable slicing algorithms.

  9. Program governance

    CERN Document Server

    Khan, Muhammad Ehsan

    2014-01-01

    FOUNDATION OF GOVERNANCEGovernanceDefining GovernanceGovernance at Multiple LevelsSummaryReferencesTransaction Cost EconomicsTransactions-Core Elements and Attributes     Behavioral Assumptions     Governance Structure AttributesHazards of Concern     Incomplete Contracting     Bilateral Dependency and Fundamental Transformation     Adaptation or MaladaptationLinking Governance, Governance Structures, and ContractsThe Impact of Asset Specificity and Behavioral Assumptions on ContractsAp

  10. Guidelines for dynamic international programs

    International Nuclear Information System (INIS)

    Matters of global concern-deforestation, global warming, biodiversity loss, sustainable development, fuelwood crises, watershed destruction, and large-scale flooding-frequently involve forests and natural resources. In the future, university students will enter a global setting that more than ever depends on a strong knowledge of international issues. USA land-grant universities are attempting to prepare students for this challenge by improving their international programs including forestry. To improve university programs, several factors will need to be addressed and are discussed, with examples, in this article: commitment of the faculty; program specialization; geographic specialization; reward systems for international contributions; international collaboration; recycled dollars within the university; active teaching programs; research; extention and outreach; language training; international faculty; travel grants; twinning relationships with sister institutions; selective in pursuit of international development assistance; and study centers. 6 refs

  11. Distance Dependent Chinese Restaurant Processes

    OpenAIRE

    Blei, David M.; Frazier, Peter I.

    2009-01-01

    We develop the distance dependent Chinese restaurant process (CRP), a flexible class of distributions over partitions that allows for non-exchangeability. This class can be used to model many kinds of dependencies between data in infinite clustering models, including dependencies across time or space. We examine the properties of the distance dependent CRP, discuss its connections to Bayesian nonparametric mixture models, and derive a Gibbs sampler for both observed and mixture settings. We s...

  12. Welfare Dependency among Danish Immigrants.

    OpenAIRE

    Blume, Kræn; Verner, Mette

    2006-01-01

    In this paper, we investigate determinants of the welfare dependency among immigrants in an assimilation framework. The duration of stay is a major determinant of welfare dependency. Also, assimilation patterns vary substantially across immigrants from developed and less devel-oped countries, respectively. The late arriving immigrants are relatively more dependent on transfers, explaining part of the general increase in welfare dependency during the latest years. This is partly attributed to ...

  13. A case of etizolam dependence.

    Science.gov (United States)

    Gupta, Sumit; Garg, Bhavuk

    2014-01-01

    Etizolam is a thienodiazepine anxiolytic which is said to have lower dependence potential than other benzodiazepines. We report a case of etizolam dependence in a young male with social anxiety disorder and moderate depression. This case report highlights the fact that the same caution be exercised while prescribing etizolam with respect to its potential to cause dependence as with any other benzodiazepine. PMID:25538342

  14. A case of etizolam dependence

    OpenAIRE

    Sumit Gupta; Bhavuk Garg

    2014-01-01

    Etizolam is a thienodiazepine anxiolytic which is said to have lower dependence potential than other benzodiazepines. We report a case of etizolam dependence in a young male with social anxiety disorder and moderate depression. This case report highlights the fact that the same caution be exercised while prescribing etizolam with respect to its potential to cause dependence as with any other benzodiazepine.

  15. Quantum Predicative Programming

    OpenAIRE

    Tafliovich, Anya; Hehner, E. C. R.

    2006-01-01

    The subject of this work is quantum predicative programming -- the study of developing of programs intended for execution on a quantum computer. We look at programming in the context of formal methods of program development, or programming methodology. Our work is based on probabilistic predicative programming, a recent generalisation of the well-established predicative programming. It supports the style of program development in which each programming step is proven correct as it is made. We...

  16. Telemedicine Program

    Science.gov (United States)

    1996-01-01

    Since the 1970s, NASA has been involved in the research and demonstration of telemedicine for its potential in the care of astronauts in flight and Earth-bound applications. A combination of NASA funding, expertise and off-the-shelf computer and networking systems made telemedicine possible for a medically underserved hospital in Texas. Through two-way audio/video relay, the program links pediatric oncology specialists at the University of Texas Health Science Center in San Antonio to South Texas Hospital in Harlingen, providing easier access and better care to children with cancer. Additionally, the hospital is receiving teleclinics on pediatric oncology nursing, family counseling and tuberculosis treatment. VTEL Corporation, Sprint, and the Healthcare Open Systems and Trials Consortium also contributed staff and hardware.

  17. Apollo Program

    Science.gov (United States)

    1963-01-01

    Construction of the track which runs in front of Model 2. Technicians work on Model 1, the 20-foot sphere. Project LOLA or Lunar Orbit and Landing Approach was a simulator built at Langley to study problems related to landing on the lunar surface. It was a complex project that cost nearly $2 million dollars. James Hansen wrote: 'This simulator was designed to provide a pilot with a detailed visual encounter with the lunar surface; the machine consisted primarily of a cockpit, a closed-circuit TV system, and four large murals or scale models representing portions of the lunar surface as seen from various altitudes. The pilot in the cockpit moved along a track past these murals which would accustom him to the visual cues for controlling a spacecraft in the vicinity of the moon. Unfortunately, such a simulation--although great fun and quite aesthetic--was not helpful because flight in lunar orbit posed no special problems other than the rendezvous with the LEM, which the device did not simulate. Not long after the end of Apollo, the expensive machine was dismantled.' (p. 379) Ellis J. White wrote in his paper 'Discussion of Three Typical Langley Research Center Simulation Programs,' 'The model system is designed so that a television camera is mounted on a camera boom on each transport cart and each cart system is shared by two models. The cart's travel along the tracks represents longitudinal motion along the plane of a nominal orbit, vertical travel of the camera boom represents latitude on out-of-plane travel, and horizontal travel of the camera boom represents altitude changes.' Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, NASA SP-4308, p. 379; Ellis J. White, 'Discussion of Three Typical Langley Research Center Simulation Programs,' Paper presented at the Eastern Simulation Council (EAI's Princeton Computation Center), Princeton, NJ, October 20, 1966.

  18. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Base Oncology Medical Home Accreditation Pilot Program Stereotactic Breast Biopsy Accreditation Program Cancer Program Staff Information Surgeon Specific Registry Surgeon Specific ...

  19. Annotated Answer Set Programming

    OpenAIRE

    Straccia, Umberto

    2005-01-01

    We present Annotated Answer Set Programming, that extends the ex pressive power of disjunctive logic programming with annotation terms, taken from the generalized annotated logic programming framework.

  20. A Mars Exploration Discovery Program

    Science.gov (United States)

    Hansen, C. J.; Paige, D. A.

    2000-07-01

    The Mars Exploration Program should consider following the Discovery Program model. In the Discovery Program a team of scientists led by a PI develop the science goals of their mission, decide what payload achieves the necessary measurements most effectively, and then choose a spacecraft with the capabilities needed to carry the payload to the desired target body. The primary constraints associated with the Discovery missions are time and money. The proposer must convince reviewers that their mission has scientific merit and is feasible. Every Announcement of Opportunity has resulted in a collection of creative ideas that fit within advertised constraints. Following this model, a "Mars Discovery Program" would issue an Announcement of Opportunity for each launch opportunity with schedule constraints dictated by the launch window and fiscal constraints in accord with the program budget. All else would be left to the proposer to choose, based on the science the team wants to accomplish, consistent with the program theme of "Life, Climate and Resources". A proposer could propose a lander, an orbiter, a fleet of SCOUT vehicles or penetrators, an airplane, a balloon mission, a large rover, a small rover, etc. depending on what made the most sense for the science investigation and payload. As in the Discovery program, overall feasibility relative to cost, schedule and technology readiness would be evaluated and be part of the selection process.

  1. On SAT Technologies for dependency management and beyond

    OpenAIRE

    Le Berre, Daniel; Parrain, Anne

    2008-01-01

    SAT solvers technology is now mature enough to be part of the engineer toolbox side by side with Mixed Integer Programming and Constraint Programming tools. As of June 2008, two great pieces of software are using SAT technology to manage dependency like problems: the open source Linux distribution OpenSuse 11.0, released on June 19, 2008, integrates a custom SAT solver in their dependency manager Zypp. The new update manager of Eclipse 3.4, called Equinox p2, also uses SAT technology to resol...

  2. VARIABILIDAD GENÉTICA DE LOTES DE Brycon orbignyanus UTILIZADOS EN PROGRAMAS DE REPOBLAMIENTO: MANEJO Y CONSERVACIÓN Genetic Variability in Brycon orbignyanus Stocks Used in Stocking Programs: Management and Conservation

    Directory of Open Access Journals (Sweden)

    NELSON M LOPERA-BARRERO

    ecosystem. The objective of this study was to estimate and analyze the genetic variability of Brycon orbignyanus stocks and offspring used in stocking programs, using the molecular marker RAPD (Random Amplified Polymorphic DNA. Fifty eight broodstocks of two stocks (A and C and thirty offspring larvae of the stock A (B belonging to the Estação de Aqüiicultura e Hidrologia da Duke Energy International (Geração Paranapanema; São Paulo, Brazil were analyzed. The results of genetic variability estimated by the Shannon Index diversity (A: 0.3184; B: 0.3433 and C: 0.3687 and for the percentage of polymorphic fragments (A: 54.02%; B: 57.47% and C: 58.62% showed that the genetic variability was maintained in the offspring, due possibly to the appropriate reproductive management and the founder effect. On the contrary, the variability found among the two broodstocks indicates a genetic similarity, in spite of being natives of different fish farming's. This result is verified in the moderate value of genetic differentiation found (0.0968, in the high Nm (4.67 and the dendrogram, which suggests that the stocks hold a similar genetic pool.

  3. The ParaScope parallel programming environment

    Science.gov (United States)

    Cooper, Keith D.; Hall, Mary W.; Hood, Robert T.; Kennedy, Ken; Mckinley, Kathryn S.; Mellor-Crummey, John M.; Torczon, Linda; Warren, Scott K.

    1993-01-01

    The ParaScope parallel programming environment, developed to support scientific programming of shared-memory multiprocessors, includes a collection of tools that use global program analysis to help users develop and debug parallel programs. This paper focuses on ParaScope's compilation system, its parallel program editor, and its parallel debugging system. The compilation system extends the traditional single-procedure compiler by providing a mechanism for managing the compilation of complete programs. Thus, ParaScope can support both traditional single-procedure optimization and optimization across procedure boundaries. The ParaScope editor brings both compiler analysis and user expertise to bear on program parallelization. It assists the knowledgeable user by displaying and managing analysis and by providing a variety of interactive program transformations that are effective in exposing parallelism. The debugging system detects and reports timing-dependent errors, called data races, in execution of parallel programs. The system combines static analysis, program instrumentation, and run-time reporting to provide a mechanical system for isolating errors in parallel program executions. Finally, we describe a new project to extend ParaScope to support programming in FORTRAN D, a machine-independent parallel programming language intended for use with both distributed-memory and shared-memory parallel computers.

  4. Gologit2: Generalized Logistic Regression Models for Ordinal Dependent Variables

    OpenAIRE

    Richard Williams

    2005-01-01

    -gologit2- is a user-written program that estimates generalized logistic regression models for ordinal dependent variables. The actual values taken on by the dependent variable are irrelevant except that larger values are assumed to correspond to "higher" outcomes. A major strength of -gologit2- is that it can also estimate two special cases of the generalized model: the proportional odds model and the partial proportional odds model. Hence, -gologit2- can estimate models that are less restri...

  5. Open systems dependability dependability engineering for ever-changing systems

    CERN Document Server

    Tokoro, Mario

    2015-01-01

    The book describes a fundamentally new approach to software dependability, considering a software system as an ever-changing system due to changes in service objectives, users' requirements, standards and regulations, and to advances in technology. Such a system is viewed as an Open System since its functions, structures, and boundaries are constantly changing. Thus, the approach to dependability is called Open Systems Dependability. The DEOS technology realizes Open Systems Dependability. It puts more emphasis on stakeholders' agreement and accountability achievement for business/service cont

  6. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Cancer Liaison Program Commission on Cancer National Cancer Data Base Oncology Medical Home Accreditation Pilot Program Stereotactic ... About Trauma Programs Stop the Bleed National Trauma Data Bank Trauma Quality Improvement Program Mentoring for Excellence ...

  7. Functional Python programming

    CERN Document Server

    Lott, Steven

    2015-01-01

    This book is for developers who want to use Python to write programs that lean heavily on functional programming design patterns. You should be comfortable with Python programming, but no knowledge of functional programming paradigms is needed.

  8. Human Reliability Program Overview

    Energy Technology Data Exchange (ETDEWEB)

    Bodin, Michael

    2012-09-25

    This presentation covers the high points of the Human Reliability Program, including certification/decertification, critical positions, due process, organizational structure, program components, personnel security, an overview of the US DOE reliability program, retirees and academia, and security program integration.

  9. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program for Breast Centers National Accreditation Program for Breast Centers About NAPBC Accreditation Education Patient Resources Center Resources NAPBC Standards News Cancer Cancer Programs Cancer Programs American Joint Committee on ...

  10. Stop smoking support programs

    Science.gov (United States)

    Smokeless tobacco - stop smoking programs; Stop smoking techniques; Smoking cessation programs; Smoking cessation techniques ... It is hard to quit smoking if you are acting alone. Smokers may have a ... of quitting with a support program. Stop smoking programs ...

  11. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program Outside Activities Member Communities Military Health System Strategic Partnership ACS Archives Board of Governors Advisory Councils Quality Programs Quality Programs Overview About Quality Programs ACS Leadership in Quality ACS Leadership in Quality Inspiring Quality ...

  12. The Study of early maladaptive Schemas in Men Dependent on Drugs and those Not Dependent

    Directory of Open Access Journals (Sweden)

    MR Firoozi

    2015-11-01

    Full Text Available Introduction and Objectives of the Study Dependence on drugs is a prevalent problem throughout the world, in general and in Iran, in particular. Such a phenomenon is associated with numerous negative consequences. Given the changes in the consumption patterns in different countries, especially in Iran, and the abuse of drugs, identifying the factors which may pave the way for drug abuse is absolutely essential, which can be taken into account in setting the objectives of therapy programs. Cognizant of this, the present study has sought to study early maladaptive schemas in men dependent on drugs and those that are not. Materials and Method: The research design adopted in the present study was causal-comparative. The populaiton of interest was all the men dependent on drugs in the city of Yasouj, who had presented to recovery centers affiliated to welfare organization and Yasouj University of Medical Sciences in the year 2014 and were undergoing treatment. Using multi-stage cluster sampling, initially out of 23 centers for recovery programs, four centers were randomly chosen. Following that, out of each center, 20 and in total, 80 clients were chosen as the sample through convenience sampling. In addition, 80 men not dependent on drugs were chosen through matching with the sample dependent on drugs in terms of age, gender and locality. For the purpsoe of measuing early maladaptive schemas, we made use of the short version of Young’s early maladaptive Schemas Questionnaire. In order to determine the prevalent schemas in men dependent on drugs and those not dependent and the difference between the two groups, use was made of independent-sample t-test and effect size (d. Findings: The findings suggest that mean values of those dependent on drugs in all the schemas in quesiton were significantly higher than those of men not dependent. Although the difference in effect size of all schemas fell in the domain of the large effect, the largest

  13. Nonlinear Programming Method for Dynamic Programming

    OpenAIRE

    Yongyang Cai; Judd, Kenneth L; Lontzek, Thomas S.; Valentina Michelangeli; Che-Lin Su

    2013-01-01

    A nonlinear programming formulation is introduced to solve infinite horizon dynamic programming problems. This extends the linear approach to dynamic programming by using ideas from approximation theory to avoid inefficient discretization. Our numerical results show that this nonlinear programming method is efficient and accurate.

  14. Behavioral program synthesis with genetic programming

    CERN Document Server

    Krawiec, Krzysztof

    2016-01-01

    Genetic programming (GP) is a popular heuristic methodology of program synthesis with origins in evolutionary computation. In this generate-and-test approach, candidate programs are iteratively produced and evaluated. The latter involves running programs on tests, where they exhibit complex behaviors reflected in changes of variables, registers, or memory. That behavior not only ultimately determines program output, but may also reveal its `hidden qualities' and important characteristics of the considered synthesis problem. However, the conventional GP is oblivious to most of that information and usually cares only about the number of tests passed by a program. This `evaluation bottleneck' leaves search algorithm underinformed about the actual and potential qualities of candidate programs. This book proposes behavioral program synthesis, a conceptual framework that opens GP to detailed information on program behavior in order to make program synthesis more efficient. Several existing and novel mechanisms subs...

  15. A case of etizolam dependence

    Directory of Open Access Journals (Sweden)

    Sumit Gupta

    2014-01-01

    Full Text Available Etizolam is a thienodiazepine anxiolytic which is said to have lower dependence potential than other benzodiazepines. We report a case of etizolam dependence in a young male with social anxiety disorder and moderate depression. This case report highlights the fact that the same caution be exercised while prescribing etizolam with respect to its potential to cause dependence as with any other benzodiazepine.

  16. A rare case modafinil dependence

    Directory of Open Access Journals (Sweden)

    Raman Krishnan

    2015-01-01

    Full Text Available Modafinil, a non-amphetamine psychostimulant, is indicated for narcolepsy, shift work sleep disorder and severe obstructive sleep apnea syndrome. Modafinil is prescribed at the dose of 100 mg once in a day or as two doses, 12 h apart in a day. It has also been found that it reduces cocaine dependence and withdrawal phenomenon. Modafinil is claimed to have very low liability for abuse and dependence. Here we report a rare case of modafinil dependence.

  17. Two Generations of Path Dependence

    DEFF Research Database (Denmark)

    Madsen, Mogens Ove

      Even if there is no fully articulated and generally accepted theory of Path Dependence it has eagerly been taken up across a wide range of social sciences - primarily coming from economics. Path Dependence is most of all a metaphor that offers reason to believe, that some political, social or e...... economic processes have multiple possible paths of outcomes, rather than a unique path of equilibria. The selection among outcomes may depend on contingent choices or events - outcomes of path-dependent processes require a very relevant study - a perception of history....

  18. Inter-dependence not Over-dependence: Reducing Urban Transport Energy Dependence

    Energy Technology Data Exchange (ETDEWEB)

    Saunders, Michael James; Rodrigues da Silva, Antonio Nelson

    2007-07-01

    A major issue of concern in today's world is urban transport energy dependence and energy supply security. In an energy inter-dependent world, energy over-dependence brings risks to urban transport systems. Many urban areas are over-dependent on finite petroleum resources for transport. New technology and the development and integration of renewable resources into transport energy systems may reduce some of the current transport energy dependence of urban areas. However, the most effective means of reducing energy dependence is to first design urban areas for this condition. An urban policy framework is proposed that requires transport energy dependence to be measured and controlled in the urban development process. A new tool has been created for this purpose, the Transport Energy Specification (TES), which measures transport energy dependence of urban areas. This creates the possibility for cities to regulate urban development with respect to energy dependence. Trial assessments were performed in Germany, New Zealand and Brazil; initial analysis by transport and government professionals shows promise of this tool being included into urban policy. The TES combined with a regulatory framework has the potential to significantly reduce transport energy consumption and dependence in urban areas in the future. (auth)

  19. System for Structural Synthesis Combines Finite-Element Analysis and Optimization Programs

    Science.gov (United States)

    Rogers, J. L., Jr.

    1984-01-01

    Programming System for Structural Synthesis, EAL/PROSSS, provides structural-synthesis capability by combining EAL and CONMIN computer programs with set of interface procedures. EAL is general-purpose finiteelement structural-analysis program; CONMIN is general-purpose optimization program. User supplies two smaller problem-dependent programs to define design variables, constraints, and objective function.

  20. An Overview of the WIN Program: Its Objectives, Accomplishments, and Problems.

    Science.gov (United States)

    Comptroller General of the U.S., Washington, DC.

    The Work Incentive (WIN) program is supposed to help recipients of Aid to Families with Dependent Children (AFDC) to get jobs through a program of training, work experience, and employment while reducing the cost of the AFDC program. Because of concerns raised about the program, the Government Accounting Office (GAO) assessed the program to…

  1. 78 FR 63143 - VA Dental Insurance Program-Federalism

    Science.gov (United States)

    2013-10-23

    ... AFFAIRS 38 CFR Part 17 RIN 2900-AO86 VA Dental Insurance Program--Federalism AGENCY: Department of... its regulations related to the VA Dental Insurance Program (VADIP), a pilot program to offer premium-based dental insurance to enrolled veterans and certain survivors and dependents of...

  2. The Cost of Quality Out-of-School-Time Programs

    Science.gov (United States)

    Grossman, Jean Baldwin; Lind, Christianne; Hayes, Cheryl; McMaken, Jennifer; Gersick, Andrew

    2009-01-01

    Funders and program planners want to know: What does it cost to operate a high-quality after-school or summer program? This study answers that question, discovering that there is no "right" number. Cost varies substantially, depending on the characteristics of the participants, the goals of the program, who operates it and where it is located.…

  3. The Use of Reverse Engineering to Analyse Student Computer Programs.

    Science.gov (United States)

    Vanneste, Philip; And Others

    1996-01-01

    Discusses how the reverse engineering approach can generate feedback on computer programs without the user having any prior knowledge of what the program was designed to do. This approach uses the cognitive model of programming knowledge to interpret both context independent and dependent errors in the same words and concepts as human programmers.…

  4. 基于风电预测误差随机性的火储联合相关机会规划调度%Dependent Chance Programming Dispatching of Integrated Thermal Power Generation and Energy Storage System Based on Wind Power Forecasting Error

    Institute of Scientific and Technical Information of China (English)

    赵书强; 王扬; 徐岩

    2014-01-01

    Along with the increase of capacity of wind power on grid operation, it is getting increasingly more important to use the information of wind power forecasting error properly to dispatch grid which contains wind power in real time. This paper studied dispatching of integrated thermal power generation and energy storage system based on stochastic wind power forecasting error. To begin with, the paper built a segmented error probability distributions model according to wind power forecasting value. Then, an integrated thermal power generation-energy storage system model was built according to theory of stochastic dependent chance programming. On the basis of characteristics of thermal power and energy storage system, this paper formulated an integrated dispatching strategy, and applied differential evolution algorithm to solve the model. In the end, by using practical wind power data, this paper calculated and verified the model under four setting scenes. The results suggest that counting error distribution by segments can reflect error information more thoroughly. Besides, in integrated system, thermal power and energy storage system have preferable regulating characteristics respectively in larger and smaller time scale, and integrated dispatching can increase the stability operation probability of system.%随着风电并网容量增加,合理利用风电预测误差信息,对含风电电网的实时调度具有重要意义。基于风电功率预测误差随机性,对火储联合调度进行研究。首先,结合风电功率预测值,建立分段误差概率分布模型。然后,基于随机相关机会规划理论,建立火储联合调度模型;根据火电机组与储能系统的出力特性,制定联合调度策略;采用差分进化算法对模型进行求解。最后,利用实际风电场数据,在4种设定场景下进行计算,对模型进行验证。结果表明,分段统计误差分布能够更全面反映误差信息;火储

  5. Time-Dependent BPS Skyrmions

    CERN Document Server

    Ioannidou, Theodora

    2016-01-01

    An extended version of the BPS Skyrme model that admits time-dependent solutions is discussed. Initially, by introducing a power law at the original potential term of the BPS Skyrme model the existence, stability and structure of the corresponding solutions is investigated. Then, the frequencies and half-lifes of the radial oscillations of the constructed time-dependent solutions are determined.

  6. Dependability in E-Assessment

    Science.gov (United States)

    Weippl, Edgar R.

    2007-01-01

    E-learning systems are used by many universities for both blended learning and distance education. In both cases the success of courses depends, among many other factors, on e-learning applications that work reliably. For e-assessments the expected level of reliability and dependability is even higher. By clearly analyzing technical and…

  7. Gentoo package dependencies over time

    NARCIS (Netherlands)

    Bloemen, Remco; Amrit, Chintan; Kuhlmann, Stefan; Ordonez-Matamoros, Gonzalo

    2014-01-01

    Open source distributions such as Gentoo need to accurately track dependency relations between software packages in order to install working systems. To do this, Gentoo has a carefully authored database containing those relations. In this paper, we extract the Gentoo package dependency graph and its

  8. Frequency-dependent heat capacity

    DEFF Research Database (Denmark)

    Behrens, Claus Flensted

    The frequency–dependent heat capacity of super-cooled glycerol near the glass transition is measured using the 3w detection technique. An electrical conducting thin film with a temperature–dependent electrical resistance is deposited on a substrate. The thin film is used simultaneously as a heater...

  9. Early recognition of chemical dependence.

    Science.gov (United States)

    Maly, R C

    1993-03-01

    Chemical dependence is a leading cause of morbidity and death in the United States. At least 20% of patients seen by primary care physicians in both the outpatient and inpatient setting are chemically dependent. Up to 90% of these patients go undiagnosed by their primary physicians. Chemical dependence is defined as a chronic, progressive illness characterized by the repeated and persistent use of alcohol or drugs despite negative health, family, work, financial, or legal consequences. Primary care physicians are in an ideal position to detect chemical dependence at its earliest stages, when irreversible medical consequences and death are most likely preventable. Alcohol is the most common drug of abuse. Improving the rate of recognition of chemical dependence depends on being familiar with the constellation of physical, mental, and social indicators. Early medical manifestations of alcoholism common in the primary care setting include: gastric complaints, elevated blood pressure, palpitations, traumatic injuries, headaches, impotence, and gout. Early psychosocial manifestations common in both alcohol and drug dependence include anxiety, depression, insomnia, persistent relationship conflicts, work or school problems, and financial or legal problems. Particularly useful laboratory indicators of alcoholism include elevated levels of GGT and MCV, both displaying high specificity, with the GGT level being the most sensitive. Similarly specific laboratory tests for drug dependence are not available. Any patient presenting with any of the above medical, psychosocial, or laboratory manifestations should be screened for chemical dependence. The CAGE questionnaire for alcoholism, a four-question test, is particularly well suited to the primary care setting, where it can be administered in fewer than 60 seconds. The CAGE has demonstrated high sensitivity (in the 80% range) and specificity (approximately 85%) for alcoholism. Comparably convenient instruments do not yet exist

  10. Purely Functional Structured Programming

    OpenAIRE

    Obua, Steven

    2010-01-01

    The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that m...

  11. System programming languages

    OpenAIRE

    Šmit, Matej

    2016-01-01

    Most operating systems are written in the C programming language. Similar is with system software, for example, device drivers, compilers, debuggers, disk checkers, etc. Recently some new programming languages emerged, which are supposed to be suitable for system programming. In this thesis we present programming languages D, Go, Nim and Rust. We defined the criteria which are important for deciding whether programming language is suitable for system programming. We examine programming langua...

  12. Expressing Inter-task Dependencies between Parallel Stencil Operations

    DEFF Research Database (Denmark)

    Larsen, Per; Karlsson, Sven; Madsen, Jan

    2010-01-01

    of parallel program behaviour which are used to evaluate the feasibility of a particular design. However, automatically extracting an accurate task graph from source code is challenging. This paper investigates how to describe data dependencies to aid tools based on program analysis in extracting task graphs...... from source code. We will examine a common parallel programming pattern - stencil operations - and show that even for such codes with a regular control flow, the precise dependencies between two stencil operations cannot always be determined at compile time. We introduce a language construct which i...... image processing applications. The coding effort is low - at most one line of code per parallel loop was added. The performance impact is evaluated on a quad-core Linux workstation and we observe no statistically significant slowdown....

  13. Inertial fusion program-present status

    International Nuclear Information System (INIS)

    The present status of the inertial fusion program is reviewed. The program has two major applications, one to military areas, the other to longterm energy needs. The near-term program is described by a 5-year program plan that coordinates research and culminates in a 1987 decision. The near-term program strategy is to build and operate the three new large facilities, ANTARES, NOVA, and PBFA II in order to maximize the physics data base needed to evaluate the drivertarget requirements for ignition and higher gain. Low-cost driver technology will also play an important role in the 1987 program decision. Depending on the outcome of this decision, there is a succession of archetypical facilities and associated systems studies necessary to achieve goals for long-term energy needs through inertial fusion. These are briefly discussed

  14. Glucose-dependent insulinotropic polypeptide

    DEFF Research Database (Denmark)

    Christensen, Mikkel; Vedtofte, Louise; Holst, Jens Juul;

    2011-01-01

    OBJECTIVE To evaluate the glucose dependency of glucose-dependent insulinotropic polypeptide (GIP) effects on insulin and glucagon release in 10 healthy male subjects ([means ± SEM] aged 23 ± 1 years, BMI 23 ± 1 kg/m2, and HbA1c 5.5 ± 0.1%). RESEARCH DESIGN AND METHODS Saline or physiological doses...... contrast, GIP increases glucagon levels during fasting and hypoglycemic conditions, where it has little or no effect on insulin secretion. Thus, GIP seems to be a physiological bifunctional blood glucose stabilizer with diverging glucose-dependent effects on the two main pancreatic glucoregulatory hormones....

  15. Mastering Ninject for dependency injection

    CERN Document Server

    Baharestani, Daniel

    2013-01-01

    Mastering Ninject for Dependency Injection teaches you the most powerful concepts of Ninject in a simple and easy-to-understand format using lots of practical examples, diagrams, and illustrations.Mastering Ninject for Dependency Injection is aimed at software developers and architects who wish to create maintainable, extensible, testable, and loosely coupled applications. Since Ninject targets the .NET platform, this book is not suitable for software developers of other platforms. Being familiar with design patterns such as singleton or factory would be beneficial, but no knowledge of depende

  16. Structured Programming: An Introduction.

    Science.gov (United States)

    Moulton, Peter

    Designed for use by computer programming teachers, this booklet presents the concepts of structured programming and provides examples of how to implement this methodology, which provides a systematic way of organizing programs so that even large and complex programs are easier to understand and modify than unstructured programs. After a brief…

  17. Visual program simulation in introductory programming education

    OpenAIRE

    Sorva, Juha

    2012-01-01

    This thesis formulates and evaluates a pedagogical technique whose goal is to help beginners learn the basics of computer programming. The technique, visual program simulation (VPS), involves the learner in interactive simulations in which the learner takes on the role of the computer as the executor of a program. The student uses a given visualization of a so-called notional machine, an abstract computer, to illustrate what happens in memory as the computer processes the program. The purpose...

  18. Energy Technology Programs: program summaries for 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    The Energy Technology Programs in the BNL Department of Energy and Environment cover a broad range of activities, namely: electrochemical research, chemical energy storage, chemical heat pumps, solar technology, fossil technology, catalytic systems development, space-conditioning technology, and technical support/program management. Summaries of the individual tasks associated with these activities along with publications, significant accomplishments, and program funding levels are presented.

  19. Dependence of maxima in space

    International Nuclear Information System (INIS)

    We evaluate the dependence among large values of a spatial process of maxima trough a coefficient that can be applied in natural, technical and societal extreme phenomena. Its main properties are: a) k locations can be taken into account; b) it takes values in [0,1] and higher values indicate stronger dependence; c) it is independent of the univariate marginal distributions of the random field; d) it can be related with other coefficients in the literature such as the tail dependence and the extremal coefficients; e) it agrees with the concordance property for multivariate distributions; f) it has as a particular case the variogram from geostatistics; g) it can be easily estimated. We illustrate the application of the introduced coefficient with the estimation of the degree of dependence among large values of the amount of tritium in drinking water for tree cities

  20. Modeling Dependencies in Critical Infrastructures

    NARCIS (Netherlands)

    Nieuwenhuijs, A.H.; Luiijf, H.A.M.; Klaver, M.H.A.

    2009-01-01

    This paper describes a model for expressing critical infrastructure dependencies. The model addresses the limitations of existing approaches with respect to clarity of definition, support for quality and the influence of operating states of critical infrastructures and environmental factors.

  1. ANABOLIC ANDROGENIC STEROIDS AND DEPENDENCE

    Directory of Open Access Journals (Sweden)

    IHSAN SARI

    2010-12-01

    Full Text Available Anabolic androgenic steroids are used for sportive, cosmetic, therapeutic and occupational reasons and there are many side effects reported (George, 2005; Nieminen et al., 1996; O'Sullivan et al., 2000. Prevalence of anabolic steroids’ use also indicates the importance of this topic. Moreover, it is now known that use of anabolic steroids could lead to dependence which could be psychological or/and physiological (Copeland et al., 2000. It isimportant to know about all aspects of anabolic steroids including dependence. Therefore, this study has attempted to give an insight into use of anabolic steroids and dependence. The discussion will focus on prevalence, reasons, and side effects of use and physiological and psychological dependence

  2. Extending OWL with Explicit Dependency

    OpenAIRE

    Calbimonte, Jean-Paul; Porto, Fabio

    2007-01-01

    Functional Dependency has been extensively studied in database theory. It provides an elegant formalism for specifying key constraints and is the basis for normalization theory used in Relational database design. Given its known axiomatization through logical implications it is expected that the ontology community would be interested in investigating its applicability to conceptual modeling. This paper investigates the extension of OWL ontologies with functional dependencies. In particular, ...

  3. Trust, dependence and interorganizational systems

    OpenAIRE

    Ibrahim, M.K.M.

    2006-01-01

    Organizations form interorganizational relationships and utilize information technology to improve performance. This thesis discusses the influences of dependence and different types of trust on the use of interorganizational systems and subsequently the attainment of strategic benefits. The findings indicate that dependence can influence efforts of individuals, internal business-processes and knowledge repositories. The findings also indicate that when trust is based on perceptions of compet...

  4. A Survey Of Software Dependability

    OpenAIRE

    Sarma, VVS

    1987-01-01

    This paper presents on overview of the issues in precisely defining, specifying and evaluating the dependability of software, particularly in the context of computer controlled process systems. Dependability is intended to be a generic term embodying various quality factors and is useful for both software and hardware. While the developments in quality assurance and reliability theories have proceeded mostly in independent directions for hardware and software systems, we present here the ca...

  5. Testing Implication of Probabilistic Dependencies

    OpenAIRE

    Wong, Michael S. K. M.

    2013-01-01

    Axiomatization has been widely used for testing logical implications. This paper suggests a non-axiomatic method, the chase, to test if a new dependency follows from a given set of probabilistic dependencies. Although the chase computation may require exponential time in some cases, this technique is a powerful tool for establishing nontrivial theoretical results. More importantly, this approach provides valuable insight into the intriguing connection between relational databases and probabil...

  6. Fossil energy program. Summary document

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-05-01

    This program summary document presents a comprehensive overview of the research, development, and demonstration (RD and D) activities that will be performed in FY 1981 by the Assistant Secretary for Fossil Energy (ASFE), US Department of Energy (DOE). The ASFE technology programs for the fossil resources of coal, petroleum (including oil shale) and gas have been established with the goal of making substantive contributions to the nation's future supply and efficienty use of energy. On April 29, 1977, the Administration submitted to Congress the National Energy Plan (NEP) and accompanying legislative proposals designed to establish a coherent energy policy structure for the United States. Congress passed the National Energy Act (NEA) on October 15, 1978, which allows implementation of the vital parts of the NEP. The NEP was supplemented by additional energy policy statements culminating in the President's address on July 15, 1979, presenting a program to further reduce dependence on imported petroleum. The passage of the NEA-related energy programs represent specific steps by the Administration and Congress to reorganize, redirect, and clarify the role of the Federal Government in the formulation and execution of national energy policy and programs. The energy technology RD and D prog4rams carried out by ASFE are an important part of the Federal Government's effort to provide the combination and amounts of energy resources needed to ensure national security and continued economic growth.

  7. Dependência de drogas

    Directory of Open Access Journals (Sweden)

    Miriam Garcia-Mijares

    2006-01-01

    Full Text Available O texto discute três teorias atuais de dependência de drogas: a Teoria Comportamental da dependência como escolha de Heyman, a Teoria da Sensibilização do incentivo de Robinson e Berridge, e a Teoria Neurobiológica da dependência como escolha, de Kalivas. Todas concordam em caracterizar a dependência como resultante de processos de aprendizagem em que droga e estímulos associados a seus efeitos adquirem controle potente sobre o comportamento. Diferenciam-se quanto aos processos de aprendizagem envolvidos. A Teoria Comportamental enfatiza componentes operantes e sustenta que o consumo repetido de drogas diminui o valor reforçador de atividades concorrentes. A Teoria da Sensibilização enfatiza componentes respondentes, propondo a dependência como resultado da sensibilização da potência eliciadora de estímulos condicionados aos efeitos da droga. A Teoria Neurobiológica integra as duas primeiras, descrevendo as mudanças no circuito do reforço que acontecem no processo de dependência.

  8. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Accreditation Program for Breast Centers About NAPBC Accreditation Education Patient Resources Center Resources NAPBC Standards News Cancer ... Program for Hospitals Trauma Systems Consultation Program Trauma Education Publications and Posters Injury Prevention and Control Education ...

  9. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Shop/Donate ( 0 ) Items American College of Surgeons Education Patients and Family Skills Programs Ostomy Home Skills Program Ostomy Home Skills Program Adult Ostomy Pediatric Ostomy Programa de Destrezas para manejo ...

  10. Ostomy Home Skills Program

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    Full Text Available ... Member Chapter Leader RAS-ACS Leader YFA Leader Leadership & Advocacy Summit Operation Giving Back Operation Giving Back ... Programs Quality Programs Overview About Quality Programs ACS Leadership in Quality ACS Leadership in Quality Inspiring Quality ...

  11. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection Update Your Profile Scholarships, Fellowships, and Awards ... SSC Membership Directory Annual Meeting Mentorship Program Outside Activities Member Communities Military Health System Strategic Partnership ACS ...

  12. Masonry Program Standards.

    Science.gov (United States)

    Georgia Univ., Athens. Dept. of Vocational Education.

    This publication contains statewide standards for the masonry program in Georgia. The standards are divided into 12 categories: foundations (philosophy, purpose, goals, program objectives, availability, evaluation); admissions (admission requirements, provisional admission requirements, recruitment, evaluation and planning); program structure…

  13. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Programs Educational Programs SESAP SESAP Sampler SRGS ACS Fundamentals of Surgery Curriculum Transition to Practice Program ACS/ ... Education Advanced Trauma Life Support Trauma Evaluation and Management Advanced Trauma Operative Management Rural Trauma Team Development ...

  14. Quantum Predicative Programming

    CERN Document Server

    Tafliovich, A; Tafliovich, Anya

    2006-01-01

    The subject of this work is quantum predicative programming -- the study of developing of programs intended for execution on a quantum computer. We look at programming in the context of formal methods of program development, or programming methodology. Our work is based on probabilistic predicative programming, a recent generalisation of the well-established predicative programming. It supports the style of program development in which each programming step is proven correct as it is made. We inherit the advantages of the theory, such as its generality, simple treatment of recursive programs, time and space complexity, and communication. Our theory of quantum programming provides tools to write both classical and quantum specifications, develop quantum programs that implement these specifications, and reason about their comparative time and space complexity all in the same framework.

  15. [Theme: Horticulture Programs.

    Science.gov (United States)

    Henderson, Jan; And Others

    1982-01-01

    A series of articles discusses requirements for optimum growth of horticulture education programs. Includes beginning a program, simulating working conditions, the need for mechanical skills, starting a business, and other areas to be considered for a successful horticultural program. (JOW)

  16. Extracting Credible Dependencies for Averaged One-Dependence Estimator Analysis

    Directory of Open Access Journals (Sweden)

    LiMin Wang

    2014-01-01

    Full Text Available Of the numerous proposals to improve the accuracy of naive Bayes (NB by weakening the conditional independence assumption, averaged one-dependence estimator (AODE demonstrates remarkable zero-one loss performance. However, indiscriminate superparent attributes will bring both considerable computational cost and negative effect on classification accuracy. In this paper, to extract the most credible dependencies we present a new type of seminaive Bayesian operation, which selects superparent attributes by building maximum weighted spanning tree and removes highly correlated children attributes by functional dependency and canonical cover analysis. Our extensive experimental comparison on UCI data sets shows that this operation efficiently identifies possible superparent attributes at training time and eliminates redundant children attributes at classification time.

  17. Frequency dependent changes in NMDAR-dependent synaptic plasticity

    Directory of Open Access Journals (Sweden)

    Arvind eKumar

    2011-09-01

    Full Text Available The NMDAR-dependent synaptic plasticity is thought to mediate several forms of learning, and can be induced by spike trains containing a small number of spikes occurring with varying rates and timing, as well as with oscillations. We computed the influence of these variables on the plasticity induced at a single NMDAR containing synapse using a reduced model that was analytically tractable, and these findings were confirmed using detailed, multi-compartment model. In addition to explaining diverse experimental results about the rate and timing dependence of synaptic plasticity, the model made several novel and testable predictions. We found that there was a preferred frequency for inducing long-term potentiation (LTP such that higher frequency stimuli induced lesser LTP, decreasing as 1/f when the number of spikes in the stimulus was kept fixed. Among other things, the preferred frequency for inducing LTP varied as a function of the distance of the synapse from the soma. In fact, same stimulation frequencies could induce LTP or LTD depending on the dendritic location of the synapse. Next, we found that rhythmic stimuli induced greater plasticity then irregular stimuli. Furthermore, brief bursts of spikes significantly expanded the timing dependence of plasticity. Finally, we found that in the ~5-15Hz frequency range both rate- and timing-dependent plasticity mechanisms work synergistically to render the synaptic plasticity most sensitive to spike-timing. These findings provide computational evidence that oscillations can have a profound influence on the plasticity of an NMDAR-dependent synapse, and show a novel role for the dendritic morphology in this process.

  18. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Verification, Review, and Consultation Program for Hospitals Trauma Systems Consultation Program Trauma Education Publications and Posters Injury Prevention and Control Education ...

  19. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Project Team Resources News Contact Us ACS NSQIP Pediatric ACS National Surgical Quality Improvement Program Pediatric ACS National Surgical Quality Improvement Program Pediatric About ...

  20. Apoptosis: A Review of Programmed Cell Death

    OpenAIRE

    Elmore, Susan

    2007-01-01

    The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system, hormone-dependent atrophy, embryonic development and chemical-induced cell death. Inappropriate apoptosis (either too little or too much) is a factor in many human conditions incl...

  1. The psychobiology of nicotine dependence

    Directory of Open Access Journals (Sweden)

    D. J. K. Balfour

    2008-12-01

    Full Text Available There is abundant evidence to show that nicotine is the principal addictive component of tobacco smoke. The results of laboratory studies have shown that nicotine has many of the behavioural and neurobiological properties of a drug of dependence. This article focuses on the evidence that nicotine has the rewarding and reinforcing properties typical of an addictive drug and that these properties are mediated, in part, by its effects on mesolimbic dopamine neurones. However, in many experimental models of dependence, nicotine has relatively weak reinforcing properties that do not appear to explain adequately the powerful addiction to tobacco smoke experienced by many habitual smokers. Some of the reasons for this conundrum will be covered herein. This article focuses on the hypothesis that sensory stimuli and other pharmacologically active components in tobacco smoke play a pivotal role in the addiction to nicotine when it is inhaled in tobacco smoke. The article will discuss the evidence that dependence upon tobacco smoke reflects a complex interaction between nicotine and the components of the smoke, which are mediated by complementary effects of nicotine on the dopamine projections to the shell and core subdivisions of the accumbens. It will also discuss the extent to which the complexity of the dependence explains why nicotine replacement therapy does not provide a completely satisfying aid to smoking cessation and speculate on the properties treatments should exhibit if they are to provide a better treatment for tobacco dependence than those currently available.

  2. At-Sea Hake Observer Program (ASHOP) Dataset - West Coast Groundfish Observer Program and At-Sea Hake Observer Program data collection, analysis and reporting

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Observer programs are the most comprehensive fishery dependent data collection system for total mortality estimation, protected species monitoring and discard data...

  3. Dependence logic theory and applications

    CERN Document Server

    Kontinen, Juha; Väänänen, Jouko; Vollmer, Heribert

    2016-01-01

    In this volume, different aspects of logics for dependence and independence are discussed, including both the logical and computational aspects of dependence logic, and also applications in a number of areas, such as statistics, social choice theory, databases, and computer security. The contributing authors represent leading experts in this relatively new field, each of whom was invited to write a chapter based on talks given at seminars held at the Schloss Dagstuhl Leibniz Center for Informatics in Wadern, Germany (in February 2013 and June 2015) and an Academy Colloquium at the Royal Netherlands Academy of Arts and Sciences (March 2014). Altogether, these chapters provide the most up-to-date look at this developing and highly interdisciplinary field and will be of interest to a broad group of logicians, mathematicians, statisticians, philosophers, and scientists. Topics covered include a comprehensive survey of many propositional, modal, and first-order variants of dependence logic; new results concerning ...

  4. Web Services Dependency Networks Analysis

    CERN Document Server

    Cherifi1, Chantal; Santucci, Jean-François

    2013-01-01

    Along with a continuously growing number of publicly available Web services (WS), we are witnessing a rapid development in semantic-related web technologies, which lead to the apparition of semantically described WS. In this work, we perform a comparative analysis of the syntactic and semantic approaches used to describe WS, from a complex network perspective. First, we extract syntactic and semantic WS dependency networks from a collection of publicly available WS descriptions. Then, we take advantage of tools from the complex network field to analyze them and determine their topological properties. We show WS dependency networks exhibit some of the typical characteristics observed in real-world networks, such as small world and scale free properties, as well as community structure. By comparing syntactic and semantic networks through their topological properties, we show the introduction of semantics in WS description allows modeling more accurately the dependencies between parameters, which in turn could l...

  5. Aid to Families with Dependent Children Quality Control Review Panel Decisions

    Data.gov (United States)

    U.S. Department of Health & Human Services — Decisions issued by the Aid to Families with Dependent Children (AFDC) Quality Control Review Panel of the Departmental Appeals Board concerning the AFDC program...

  6. Mathematical aspects of logic programming semantics

    CERN Document Server

    Hitzler, Pascal

    2010-01-01

    Covering the authors' own state-of-the-art research results, Mathematical Aspects of Logic Programming Semantics presents a rigorous, modern account of the mathematical methods and tools required for the semantic analysis of logic programs. It significantly extends the tools and methods from traditional order theory to include nonconventional methods from mathematical analysis that depend on topology, domain theory, generalized distance functions, and associated fixed-point theory.The book covers topics spanning the period from the early days of logic programming to current times. It discusses

  7. Program Transformations in a Denotational Setting

    DEFF Research Database (Denmark)

    Nielson, Flemming

    1985-01-01

    Program transformations are frequently performed by optimizing compilers, and the correctness of applying them usually depends on data flow information. For language-to-same-language transformations, it is shown how a denotational setting can be useful for validating such program transformations....... Strong equivalence is obtained for transformations that exploit information from a class of forward data flow analyses, whereas only weak equivalence is obtained for transformations that exploit information from a class of backward data flow analyses. To obtain strong equivalence, both the original and...... the transform program must be data flow analysed, but consideration of a transformation-exploiting liveness of variables indicates that a more satisfactory approach may be possible...

  8. Waveform-dependent absorbing metasurfaces

    CERN Document Server

    Wakatsuchi, Hiroki; Rushton, Jeremiah J; Sievenpiper, Daniel F

    2014-01-01

    We present the first use of a waveform-dependent absorbing metasurface for high-power pulsed surface currents. The new type of nonlinear metasurface, composed of circuit elements including diodes, is capable of storing high power pulse energy to dissipate it between pulses, while allowing propagation of small signals. Interestingly, the absorbing performance varies for high power pulses but not for high power continuous waves (CWs), since the capacitors used are fully charged up. Thus, the waveform dependence enables us to distinguish various signal types (i.e. CW or pulse) even at the same frequency, which potentially creates new kinds of microwave technologies and applications.

  9. Models for dependent time series

    CERN Document Server

    Tunnicliffe Wilson, Granville; Haywood, John

    2015-01-01

    Models for Dependent Time Series addresses the issues that arise and the methodology that can be applied when the dependence between time series is described and modeled. Whether you work in the economic, physical, or life sciences, the book shows you how to draw meaningful, applicable, and statistically valid conclusions from multivariate (or vector) time series data.The first four chapters discuss the two main pillars of the subject that have been developed over the last 60 years: vector autoregressive modeling and multivariate spectral analysis. These chapters provide the foundational mater

  10. Sparsity considerations for dependent observations

    CERN Document Server

    Alquier, Pierre

    2011-01-01

    The aim of this paper is to provide a comprehensive introduction for the study of L1-penalized estimators in the context of dependent observations. We define a general $\\ell_{1}$-penalized estimator for solving problems of stochastic optimization. This estimator turns out to be the LASSO in the regression estimation setting. Powerful theoretical guarantees on the statistical performances of the LASSO were provided in recent papers, however, they usually only deal with the iid case. Here, we study our estimator under various dependence assumptions.

  11. Influence of broodstock age on reproductive performance in koi carp (Cyprinus carpio L.

    Directory of Open Access Journals (Sweden)

    P. Melotti

    2011-03-01

    Full Text Available The koi carp (Cyprinus carpio L. is a very important species in the ornamental fish culture. This fish, in relation to the variety of its colour patterns is very appreciated and it can obtain an higher market price compared to the common goldfish. In the last ten years, breeding goals have increasingly focused their attention to the morphological characteristics (Cherfas et al., 1992 and numerous research works were carried out on pigmentation and viability of different colour phenotypes (Jackson et al., 2000. More recently, several studies were set up in order to produce diploid gynogenotes and triploids (Rothbard et al., 1999...

  12. Captive shrimp broodstock production: Relevance of eyestalk ablation and its regeneration in gonad maturation

    Digital Repository Service at National Institute of Oceanography (India)

    Achuthankutty, C.T.; Desai, U.M.

    stream_size 10 stream_content_type text/plain stream_name Int_Symp_Fish_Nutrition_Security_21_Century_2001_144.pdf.txt stream_source_info Int_Symp_Fish_Nutrition_Security_21_Century_2001_144.pdf.txt Content-Encoding ISO-8859...

  13. Development of a broodstock diet to improve developmental competence of embryos in European eel, Anguilla anguilla

    DEFF Research Database (Denmark)

    Støttrup, Josianne Gatt; Tomkiewicz, Jonna; Jacobsen, Charlotte;

    2016-01-01

    We examined the effect of dietary arachidonic acid (ARA) and eicosapentaenoic acid (EPA) on the production of embryos and hatched larvae in the European eel, Anguilla anguilla. Two diets with high and intermediate levels of ARA and low and intermediate levels of EPA (Feed 1: ARA 1.9%, EPA 4...

  14. Modification of essential fatty acid composition in broodstock of cultured European eel Anguilla anguilla L

    DEFF Research Database (Denmark)

    Støttrup, Josianne; Jacobsen, Charlotte; Tomkiewicz, Jonna;

    2013-01-01

    Farmed eels had lower levels of arachidonic acid (20:4 n-6) (ARA) and higher ratios of eicosapentaenoic acid (20:5 n-3) (EPA):ARA compared to wild European eels collected from the Baltic Sea and southern Norwegian coast. Eels fed a formulated feed (JD) with a distribution of essential fatty acids...

  15. Performance of Macrobrachium rosenbergii broodstock fed diets with different fatty acid composition

    OpenAIRE

    Cavalli, R.O.; Lavens, P.; Sorgeloos, P

    1999-01-01

    The effect of linoleic acid (18:2n-6) and n-3 highly unsaturated fatty acids (HUFA) on the reproductive performance and offspring quality of the freshwater prawn Macrobrachium rosenbergii was evaluated in a 180-day trial. Three isonitrogenous and isolipidic diets containing different levels of fatty acids, high 18:2n-6 and n-3 HUFA concentrations, high 18:2n-6 and low n-3 HUFA, and low 18:2n-6 and n-3 HUFA, were fed ad libitum to three groups of six females. Fecundity was improved by the addi...

  16. Developing Parallel Programs

    OpenAIRE

    Ranjan Sen

    2012-01-01

    Parallel programming is an extension of sequential programming; today, it is becoming the mainstream paradigm in day-to-day information processing. Its aim is to build the fastest programs on parallel computers. The methodologies for developing a parallelprogram can be put into integrated frameworks. Development focuses on algorithm, languages, and how the program is deployed on the parallel computer.

  17. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Quality Reporting System MOC Part 4 and Recertification Software and Registration SSR Webinars SSR Login Trauma Trauma Programs Trauma Programs About Trauma Programs Stop the Bleed National Trauma Data Bank Trauma Quality Improvement Program Mentoring for Excellence in Trauma Surgery Advanced ...

  18. National Transuranic Program Charter

    International Nuclear Information System (INIS)

    The National Transuranic Program Plan and Charter describes the functional elements of the National TRU Program, organizational relationships, programmatic responsibilities, division of work scope among the various DOE organizations that comprise the program, and program baselines against which overall progress will be measured. The charter defines the authorities and responsibilities of various organizations involved in the management of TRU waste throughout the DOE complex

  19. Laser Programs Highlights 1998

    Energy Technology Data Exchange (ETDEWEB)

    Lowdermilk, H.; Cassady, C.

    1999-12-01

    This report covers the following topics: Commentary; Laser Programs; Inertial Confinement Fusion/National Ignition Facility (ICF/NIF); Atomic Vapor Laser Isotope Separation (AVLIS); Laser Science and Technology (LS&T); Information Science and Technology Program (IS&T); Strategic Materials Applications Program (SMAP); Medical Technology Program (MTP) and Awards.

  20. [PIC Program Evaluation Forms.

    Science.gov (United States)

    Short, N. J.

    These 4 questionnaires are designed to elicit teacher and parent evaluations of the Prescriptive Instruction Center (PIC) program. Included are Teacher Evaluation of Program Effectiveness (14 items), M & M Evaluation of Program Implementation (methods and materials specialists; 11 items), Teacher Evaluation of Program Effectiveness--Case Study…

  1. The Cybernetic Writing Program.

    Science.gov (United States)

    Lowe, Kelly Fisher

    This paper looks at the role of a Writing Program Administrator, and applies the idea of a cybernetic system to the administration of the program. In this cybernetic model, the Writing Program Administrator (WPA) works as both a problem solver and problem causer, with the responsibility of keeping the program in proper balance. A cybernetic…

  2. Derivation of sorting programs

    Science.gov (United States)

    Varghese, Joseph; Loganantharaj, Rasiah

    1990-01-01

    Program synthesis for critical applications has become a viable alternative to program verification. Nested resolution and its extension are used to synthesize a set of sorting programs from their first order logic specifications. A set of sorting programs, such as, naive sort, merge sort, and insertion sort, were successfully synthesized starting from the same set of specifications.

  3. Light water reactor program

    Energy Technology Data Exchange (ETDEWEB)

    Franks, S.M.

    1994-12-31

    The US Department of Energy`s Light Water Reactor Program is outlined. The scope of the program consists of: design certification of evolutionary plants; design, development, and design certification of simplified passive plants; first-of-a-kind engineering to achieve commercial standardization; plant lifetime improvement; and advanced reactor severe accident program. These program activities of the Office of Nuclear Energy are discussed.

  4. C++ Programming Language

    Science.gov (United States)

    Shaykhian, Gholam Ali

    2007-01-01

    C++ Programming Language: The C++ seminar covers the fundamentals of C++ programming language. The C++ fundamentals are grouped into three parts where each part includes both concept and programming examples aimed at for hands-on practice. The first part covers the functional aspect of C++ programming language with emphasis on function parameters and efficient memory utilization. The second part covers the essential framework of C++ programming language, the object-oriented aspects. Information necessary to evaluate various features of object-oriented programming; including encapsulation, polymorphism and inheritance will be discussed. The last part of the seminar covers template and generic programming. Examples include both user defined and standard templates.

  5. Federal Wind Energy Program. Program summary. [USA

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    The objective of the Federal Wind Energy Program is to accelerate the development of reliable and economically viable wind energy systems and enable the earliest possible commercialization of wind power. To achieve this objective for small and large wind systems requires advancing the technology, developing a sound industrial technology base, and addressing the non-technological issues which could deter the use of wind energy. This summary report outlines the projects being supported by the program through FY 1977 toward the achievement of these goals. It also outlines the program's general organization and specific program elements.

  6. Valoración de los usuarios de un programa de reducción de daños integrado en un ambulatorio de drogodependencias Users´ perception of a harm reduction program in an outpatient drug dependency treatment center

    Directory of Open Access Journals (Sweden)

    Constanza Daigre

    2010-12-01

    Full Text Available Objetivos: Explorar la perspectiva de los usuarios y analizar los factores que influyen en su vinculación en un programa de reducción de daños (REDAN que presta los siguientes servicios: intercambio de jeringuillas, espacio educativo de calor y café, programa de mantenimiento con metadona, sala de consumo higiénico supervisado, espacio para la higiene personal y seguimiento sanitario y psicosocial. Este programa presenta la particularidad de estar integrado en un ambulatorio de drogodependencias situado en un recinto hospitalario. Métodos: Estudio descriptivo realizado con metodología cualitativa. Se realizó un muestreo teórico. Se saturaron los contenidos mediante 12 entrevistas en profundidad y un grupo focal con ocho participantes. El análisis de la información se basó en la Grounded Theory. Las transcripciones literales fueron codificadas descriptivamente y luego se generaron categorías amplias. Este procedimiento se realizó en un principio por tres investigadores y finalmente un cuarto investigador trianguló la información. Resultados: Emergen cinco dimensiones (accesibilidad, servicios, relación, localización e identidad compuestas por diferentes temas valorados desde las expectativas y experiencias de los usuarios. La dimensión «identidad» otorga un elemento distintivo respecto a la vinculación con el programa. Conclusión: En general, los usuarios valoran positivamente el programa REDAN. Respecto a la vinculación, describen aspectos facilitadores y otros deficitarios que pueden suponer barreras, frente a las cuales realizan sugerencias. Aspectos como la convivencia entre los usuarios del programa REDAN y los pacientes en tratamiento orientado a la abstinencia generan ambivalencia, pero se identifica que la gestión por parte del equipo minimiza estas dificultades.Objectives: We analyzed the perspective of users enrolled in a harm reduction program that provides syringe exchange, an educational room for «warmth and

  7. Generating Consistent Program Tutorials

    DEFF Research Database (Denmark)

    Vestdam, Thomas

    In this paper we present a tool that supports construction of program tutorials. A program tutorial provides the reader with an understanding of an example program by interleaving fragments of source code and explaining text. An example program can for example illustrate how to use a library or a...... framework. We present a means for specifying the fragments of a program that are to be in-lined in the tutorial text. These in-line fragments are defined by addressing named syntactical elements, such as classes and methods, but it is also possible to address individual code lines by labeling them with...... source markers. The tool helps ensuring consistency between program tutorial and example programs by extracting fragments of source code based on the fragment specifications and by detecting when a program tutorial is addressing program fragments that do not exist. The program tutorials are presented as...

  8. Purely Functional Structured Programming

    CERN Document Server

    Obua, Steven

    2010-01-01

    The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that mainstream programmers can reap the benefits of purely functional programming like easily exploitable parallelism while using familiar structured programming syntax and without knowing concepts like monads. A second advantage is that professional purely functional programmers can often avoid hard to read functional code by using structured programming syntax that is often easier to parse mentally.

  9. Definition of a Dependent Child

    CERN Multimedia

    Human Resources Department

    2005-01-01

    The Department of Human Resources wishes to remind members of the personnel that, under the provisions of § 6 of Administrative Circular No. 5 “Dependent child”, in the case of a child over 18 years of age the status of dependent child comes to an end once a course of studies is completed. Consequently, the payment of the dependent child allowance and the child's membership of the CERN Health Insurance Scheme terminate with effect from the last day of the month in which the course of study concerned ends. In this connection, members of the personnel are reminded that children who are no longer dependent according to the Staff Rules and Regulations and who are less than 26 years of age can nevertheless opt for membership of the normal health insurance under the terms and conditions laid down in the CERN Health Insurance Rules. The Department of Human Resources also wishes to remind members of the personnel that, pursuant to Article R IV 1.17 of the Staff Regulations, a member of the personnel is requ...

  10. Network-timing-dependent plasticity

    Directory of Open Access Journals (Sweden)

    Vincent eDelattre

    2015-06-01

    Full Text Available Bursts of activity in networks of neurons are thought to convey salient information and drive synaptic plasticity. Here we report that network bursts also exert a profound effect on Spike-Timing-Dependent Plasticity (STDP. In acute slices of juvenile rat somatosensory cortex we paired a network burst, which alone induced long-term depression (LTD, with STDP-induced long-term potentiation and depression (LTP and LTD. We observed that STDP-induced LTP was either unaffected, blocked or flipped into LTD by the network burst, and that STDP-induced LTD was either saturated or flipped into LTP, depending on the relative timing of the network burst with respect to spike coincidences of the STDP event. We hypothesized that network bursts flip STDP-induced LTP to LTD by depleting resources needed for LTP and therefore developed a resource-dependent STDP learning rule. In a model neural network under the influence of the proposed resource-dependent STDP rule, we found that excitatory synaptic coupling was homeostatically regulated to produce power law distributed burst amplitudes reflecting self-organized criticality, a state that ensures optimal information coding.

  11. Mediation of flowering by a calmodulin-dependent proteinkinase

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A calmodulin-dependent protein kinase (MCK1) appeared important in regulating flowering in tobacco. The expression of modified MCK1 that lacks the C-terminal including calmodulin-binding domain upsets the flowering developmental program, leading to the abortion of flower primordia initiated on the main axis of the plant and, as well, caused the prolongation of the vegetative phase in axillary buds. The abortion process of flowers began first in the developing anthers and subsequently the entire flower senesces. In axillary buds the prolonged vegetative phase was characterized by atypical elongated, narrow, twisted leaves. These results suggested a role for calmodulin-dependent protein kinase homologs in mediating flowering.

  12. On Constraint Programming

    OpenAIRE

    Mathieu, Philippe; Keisu, Torbjörn

    1990-01-01

    This short note aims to present foundations for constraint logic programming. By logic programming, we understand in this paper the PROLOG paradigm. But it will be clear that we do reduce the problem to adding a new package to PROLOG. We argue that constraint logic programming should be defined as a new paradigm for programming: the LOGIC PROGRAMMING + SYMBOLIC COMPUTATION paradigm. Our system incorporates as a very basic, all the existing systems incorporating constraints i...

  13. Computer assisted mathematical programming

    OpenAIRE

    Lucas, CA; Mitra, G

    1987-01-01

    A Computer Assisted Mathematical Programming (Modelling) System (CAMPS) is described in this paper. The system uses program generator techniques for model creation and contrasts with earlier approaches which use a special purpose language to construct models. Thus no programming skill is required to formulate a model. In designing the system we have first analysed the salient components of the mathematical programming activity. A mathematical programming model is usually constructed by progre...

  14. Technology Commercialization Program 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  15. Learning programming: treasure hunt

    OpenAIRE

    Močnik, Mariza

    2015-01-01

    In this thesis a few teoretical basics about computational and algoritmic thinking are given, which is necessary in programming. Programming allows developing of new programs, which are constantly needed in all areas. Early learning is therfore significant for children and their future. Among modern ways of teaching programming belongs game palying, for this purpose an example board game is presented The game is called "Lov na zaklad". It was created using graphical programs and few websit...

  16. Teaching Programming with Scratch

    OpenAIRE

    Mihalič, Petra

    2014-01-01

    There are quite a few good programing languages and environments for teaching kids how to program. They help beginners learn basic programming constructs usually with help of interactive environment. In this thesis I will describe and compare a few of those languages and environments. Scratch is a language and programming environment that is also intended for learning programming using blocks that make writing complicated instructions easier and reduce beginners' difficulties with syntax erro...

  17. Multiobjective programming and planning

    CERN Document Server

    Cohon, Jared L

    2004-01-01

    This text takes a broad view of multiobjective programming, emphasizing the methods most useful for continuous problems. It reviews multiobjective programming methods in the context of public decision-making problems, developing each problem within a context that addresses practical aspects of planning issues. Topics include a review of linear programming, the formulation of the general multiobjective programming problem, classification of multiobjective programming methods, techniques for generating noninferior solutions, multiple-decision-making methods, multiobjective analysis of water reso

  18. Programming with joystick

    OpenAIRE

    Banič, Nejc

    2014-01-01

    In this thesis, we implemented a way of programming by means of gaming accessories. The main reason is that to show a diferent way of developing programs, because vast majority of programers are using two input / output devices: keyboard and mouse. These two devices have become standard and will definitely remain so in the future. For our implementation, we used high-level programming language Java and NetBeans integrated development environment. The program is actually a ...

  19. Introduction to relational programming

    OpenAIRE

    MacLennan, Bruce J.

    2013-01-01

    A new method of programming, called relational programming, is introduced. This is a style of programming in which entire relations are manipulated rather than individual data. This is analogous to functional programming, wherein entire functions are the value manipulated by the operators. Because of its ability to manipulate complex data structures other than lists, relational programming seems to have distinct advantages over other very high level languages. This paper introduces the basic ...

  20. Introduction to parallel programming

    CERN Document Server

    Brawer, Steven

    1989-01-01

    Introduction to Parallel Programming focuses on the techniques, processes, methodologies, and approaches involved in parallel programming. The book first offers information on Fortran, hardware and operating system models, and processes, shared memory, and simple parallel programs. Discussions focus on processes and processors, joining processes, shared memory, time-sharing with multiple processors, hardware, loops, passing arguments in function/subroutine calls, program structure, and arithmetic expressions. The text then elaborates on basic parallel programming techniques, barriers and race

  1. Retinoids induce Nur77-dependent apoptosis in mouse thymocytes.

    Science.gov (United States)

    Kiss, Beáta; Tóth, Katalin; Sarang, Zsolt; Garabuczi, Éva; Szondy, Zsuzsa

    2015-03-01

    Nur77 is a transcription factor, which plays a determinant role in mediating T cell receptor-induced cell death of thymocytes. In addition to regulation of transcription, Nur77 contributes to apoptosis induction by targeting mitochondria, where it can convert Bcl-2, an anti-apoptotic protein into a proapoptotic molecule. Previous studies have demonstrated that retinoids are actively produced in the mouse thymus and can induce a transcription-dependent apoptosis in mouse thymocytes. Here we show that retinoic acids induce the expression of Nur77, and retinoid-induced apoptosis is completely dependent on Nur77, as retinoids were unable to induce apoptosis in Nur77 null thymocytes. In wild-type thymocytes retinoids induced enhanced expression of the apoptosis-related genes FasL, TRAIL, NDG-1, Gpr65 and Bid, all of them in a Nur77-dependent manner. The combined action of these proteins led to Caspase 8-dependent Bid cleavage in the mitochondria. In addition, we could demonstrate the Nur77-dependent induction of STAT1 leading to enhanced Bim expression, and the mitochondrial translocation of Nur77 leading to the exposure of the Bcl-2/BH3 domain. The retinoid-induced apoptosis was dependent on both Caspase 8 and STAT1. Our data together indicate that retinoids induce a Nur77-dependent cell death program in thymocytes activating the mitochondrial pathway of apoptosis. PMID:25576519

  2. The GPD program at COMPASS

    CERN Document Server

    Sandacz, Andrzej

    2015-01-01

    The 160 GeV polarised muon beam available at CERN, with positive or negative charge, makes COMPASS a unique place for GPD studies. The first GPD related COMPASS results come from exclusive vector meson production on transversely polarised protons and deuterons. The data were taken in 2003-2010 with large solid-state polarised targets, although without detection of recoil particles. Results on various transverse target spin dependent azimuthal asymmetries are presented and their relations to GPDs are discussed. The dedicated COMPASS GPD program started in 2012 with commissioning of a new long liquid hydrogen target and new detectors such as the large recoil proton detector and the large-angle electromagnetic calorimeter. It was followed by a short pilot 'DVCS run'. The performance of the setup and first results on DVCS and exclusive $\\pi ^0$ channels have been demonstrated. The full data taking for the GPD program approved within COMPASS-II proposal is planned for 2016 and 2017.

  3. Atmospheric Radiation Measurement Program plan

    International Nuclear Information System (INIS)

    In order to understand energy's role in anthropogenic global climate change, significant reliance is being placed on General Circulation Models (GCMs). A major goal is to foster the development of GCMs capable of predicting the timing and magnitude of greenhouse gas-induced global warming and the regional effects of such warming. The Atmospheric Radiation Measurement (ARM) Program will contribute to the Department of Energy goal by improving the treatment of cloud radiative forcing and feedbacks in GCMs. Two issues will be addressed: the radiation budget and its spectral dependence and the radiative and other properties of clouds. The experimental objective of the ARM Program is to characterize empirically the radiative processes in the Earth's atmosphere with improved resolution and accuracy. A key to this characterization is the effective treatment of cloud formation and cloud properties in GCMs. Through this characterization of radiative properties, it will be possible to understand both the forcing and feedback effects. 19 refs., 4 figs., 2 tabs

  4. Hawaii Energy Strategy: Program guide

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    The Hawaii Energy Strategy program, or HES, is a set of seven projects which will produce an integrated energy strategy for the State of Hawaii. It will include a comprehensive energy vulnerability assessment with recommended courses of action to decrease Hawaii`s energy vulnerability and to better prepare for an effective response to any energy emergency or supply disruption. The seven projects are designed to increase understanding of Hawaii`s energy situation and to produce recommendations to achieve the State energy objectives of: Dependable, efficient, and economical state-wide energy systems capable of supporting the needs of the people, and increased energy self-sufficiency. The seven projects under the Hawaii Energy Strategy program include: Project 1: Develop Analytical Energy Forecasting Model for the State of Hawaii. Project 2: Fossil Energy Review and Analysis. Project 3: Renewable Energy Resource Assessment and Development Program. Project 4: Demand-Side Management Program. Project 5: Transportation Energy Strategy. Project 6: Energy Vulnerability Assessment Report and Contingency Planning. Project 7: Energy Strategy Integration and Evaluation System.

  5. Impact of Aspect-Oriented Programming on the Quality of Novices’ Programs: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Marija Katic

    2013-06-01

    Full Text Available Aspect-oriented programming has been introduced in order to increase the modularity of object-oriented programs and is claimed to improve software quality. Although there are various researches on this claim, the question to what extent aspect-oriented programming improves the quality of programs depending on a developer’s experience still remains. The purpose of this study is to investigate whether aspect-oriented programming used by novice programmers improves the quality of programs, in terms of software flexibility and readability (consequently reusability and maintainability as well. As a part of an undergraduate course in programming paradigms and languages, a systematic comparison between students’ object-oriented and aspect-oriented solutions of the same problem was driven. In order to drive this comparison we have established the basis for the development of the new quality assessment model consisting of software metrics for an objective evaluation and student survey for subjective evaluation. The results show that the use of aspect-oriented programming lead to novices’ programs that are easier to change and read (flexible and readable compared to object-oriented programs. What is more, administered survey showed that students perceive their programs as more flexible and readable.

  6. Salmonella Control Programs in Denmark

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar; Hald, Tine; Wong, Danilo Lo Fo; Madsen, M.; Korsgaard, Helle; Bager, Flemming; Gerner-Smidt, P.; Mølbak, K.

    2003-01-01

    We describe Salmonella control programs of broiler chickens, layer hens, and pigs in Denmark. Major reductions in the incidence of foodborne human salmonellosis have occurred by integrated control of farms and food processing plants. Disease control has been achieved by monitoring the herds and...... flocks, eliminating infected animals, and diversifying animals (animals and products are processed differently depending on Salmonella status) and animal food products according to the determined risk. In 2001, the Danish society saved U.S.$25.5 million by controlling Salmonella. The total annual...

  7. The Vehicle Routing Problem with Time Windows and Temporal Dependencies

    DEFF Research Database (Denmark)

    Rasmussen, Matias Sevel; Dohn, Anders Høeg; Larsen, Jesper

    to be scheduled with a certain slack between them. They refer to the vehicle problem as having interdependent time windows. Temporal dependencies have been modeled for a home care routing problem in a mixed integer programming model (MIP) which was solved with a standard MIP solver. An application with general...... temporal dependencies is also found in machine scheduling. Column generation is used to solve the problem. The pricing problem is primarily solved heuristically by local search and occasionally to optimality using a standard solver on an integer programming formulation of the pricing problem. Two compact...... is novel as well. Finally, we introduce a new set of context-free benchmark instances which enables a thorough quantitative analysis and which we hope will facilitate future research in this area. The analysis shows that, even though the time-indexed model has some nice properties, it also retains its...

  8. Methods and principles for determining task dependent interface content

    Science.gov (United States)

    Shalin, Valerie L.; Geddes, Norman D.; Mikesell, Brian G.

    1992-01-01

    Computer generated information displays provide a promising technology for offsetting the increasing complexity of the National Airspace System. To realize this promise, however, we must extend and adapt the domain-dependent knowledge that informally guides the design of traditional dedicated displays. In our view, the successful exploitation of computer generated displays revolves around the idea of information management, that is, the identification, organization, and presentation of relevant and timely information in a complex task environment. The program of research that is described leads to methods and principles for information management in the domain of commercial aviation. The multi-year objective of the proposed program of research is to develop methods and principles for determining task dependent interface content.

  9. Traditional Planetarium Programming versus Participatory Planetarium Programming.

    Science.gov (United States)

    Fletcher, Jack K.

    1980-01-01

    The results of this study indicate that, for the astronomical concepts used, no significant difference in the cognitive domain will occur between the achievement of students who experience a participatory planetarium program and students who experience a traditional lecture-demonstration program. (Author/MK)

  10. (abstract) Ulysses Solar Wind Ion Temperatures: Radial, Latitudinal, and Dynamical Dependencies

    Science.gov (United States)

    Goldstein, B. E.; Smith, E. J.; Gosling, J. T.; McComas, D. J.; Balogh, A.

    1996-01-01

    Observations of the Ulysses SWOOPS plasma experiment are used to determine the dependencies of solar wind ion temperatures upon radial distance, speed, and other parameters, and to estimate solar wind heating. Comparisons with three dimensional temperature estimates determined from the ion spectra by a least squares fitting program will be provided (only small samples of data have been reduced with this program).

  11. Analyzing Array Manipulating Programs by Program Transformation

    Science.gov (United States)

    Cornish, J. Robert M.; Gange, Graeme; Navas, Jorge A.; Schachte, Peter; Sondergaard, Harald; Stuckey, Peter J.

    2014-01-01

    We explore a transformational approach to the problem of verifying simple array-manipulating programs. Traditionally, verification of such programs requires intricate analysis machinery to reason with universally quantified statements about symbolic array segments, such as "every data item stored in the segment A[i] to A[j] is equal to the corresponding item stored in the segment B[i] to B[j]." We define a simple abstract machine which allows for set-valued variables and we show how to translate programs with array operations to array-free code for this machine. For the purpose of program analysis, the translated program remains faithful to the semantics of array manipulation. Based on our implementation in LLVM, we evaluate the approach with respect to its ability to extract useful invariants and the cost in terms of code size.

  12. Programming Models in HPC

    Energy Technology Data Exchange (ETDEWEB)

    Shipman, Galen M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-13

    These are the slides for a presentation on programming models in HPC, at the Los Alamos National Laboratory's Parallel Computing Summer School. The following topics are covered: Flynn's Taxonomy of computer architectures; single instruction single data; single instruction multiple data; multiple instruction multiple data; address space organization; definition of Trinity (Intel Xeon-Phi is a MIMD architecture); single program multiple data; multiple program multiple data; ExMatEx workflow overview; definition of a programming model, programming languages, runtime systems; programming model and environments; MPI (Message Passing Interface); OpenMP; Kokkos (Performance Portable Thread-Parallel Programming Model); Kokkos abstractions, patterns, policies, and spaces; RAJA, a systematic approach to node-level portability and tuning; overview of the Legion Programming Model; mapping tasks and data to hardware resources; interoperability: supporting task-level models; Legion S3D execution and performance details; workflow, integration of external resources into the programming model.

  13. TFE verification program

    Science.gov (United States)

    1990-03-01

    The information presented herein will include evaluated test data, design evaluations, the results of analyses and the significance of results. The program objective is to demonstrate the technology readiness of a Thermionic Fuel Element (TFE) suitable for use as the basic element in a thermionic reactor with electric power output in the 0.5 to 5.0 MW(e) range, and a full-power life of 7 years. The TF Verification Program builds directly on the technology and data base developed in the 1960s and 1970s in an AEC/NASA program, and in the SP-100 program conducted in 1983, 1984 and 1985. In the SP-100 program, the attractive features of thermionic power conversion technology were recognized but concern was expressed over the lack of fast reactor irradiation data. The TFE Verification Program addresses this concern. The general logic and strategy of the program to achieve its objectives is shown. Five prior programs form the basis for the TFE Verification Program: (1) AEC/NASA program of the 1960s and early 1970; (2) SP-100 concept development program; (3) SP-100 thermionic technology program; (4) Thermionic irradiations program in TRIGA in FY-88; and (5) Thermionic Program in 1986 and 1987.

  14. Assessment of a cancer screening program.

    Science.gov (United States)

    Rabeneck, Linda; Lansdorp-Vogelaar, Iris

    2015-12-01

    Several Asian countries are implementing nationwide cancer screening programs. Assessment of the effectiveness of these programs is critical to their success as this is the only way to ensure that the benefits of screening outweigh the harms. In this paper we focus on colorectal cancer (CRC) screening to illustrate the principles of screening program assessment. The International Agency for Research on Cancer (IARC) has defined organized screening, distinguishing it from opportunistic screening. The key advantage of organized screening is that it provides greater protection against the possible harms of screening. Since screening is a process, not simply a test, the effectiveness of a program depends on the quality of each step in the cancer screening process. The evaluation of long-term screening program outcomes (CRC incidence and mortality) will not be observable for many years, given the time it takes to plan, pilot and implement a program. However, early performance indicators of the impact of screening should be monitored to give an early indication whether the program is on track. The European Union (EU) has recommended a minimum dataset to be collected and reported regularly by a screening program. Using information from these data tables, early performance indicators can be generated (e.g., participation rate, proportion of screen-detected cancers that are early-stage). Subsequently, modeling the natural history of the disease can be very helpful to estimate long-term outcomes, making use of these directly measured early performance indicators. Modeling can also be used to estimate the cost-effectiveness of a screening program and the potential impact of changes in policy, as illustrated by its recent use in the Netherlands to change the definition of a positive fecal immunochemical test (FIT) for the CRC screening program. Programs should consider modeling as an important component of screening program evaluation. PMID:26651258

  15. MiniAgda: Integrating Sized and Dependent Types

    OpenAIRE

    Andreas Abel

    2010-01-01

    Sized types are a modular and theoretically well-understood tool for checking termination of recursive and productivity of corecursive definitions. The essential idea is to track structural descent and guardedness in the type system to make termination checking robust and suitable for strong abstractions like higher-order functions and polymorphism. To study the application of sized types to proof assistants and programming languages based on dependent type theory, we have implemented a core ...

  16. Model Penjadwalan Batch Multi Item dengan Dependent Processing Time

    OpenAIRE

    Sukoyo Sukoyo; TMA. Ari Samadhi; Bermawi P. Iskandar; Abdul Hakim Halim

    2010-01-01

    This paper investigates a development of single machine batch scheduling for multi items with dependent processing time. The batch scheduling problem is to determine simultaneously number of batch (N), which item and its size allocated for each batch, and processing sequences of resulting batches. We use total actual flow time as the objective of schedule performance. The multi item batch scheduling problem could be formulated into a biner-integer nonlinear programming model because the numbe...

  17. Tobacco use and dependence : does it originate in utero?

    OpenAIRE

    Rydell, Mina

    2014-01-01

    Prenatal nicotine exposure (such as from maternal smoking during pregnancy) has been hypothesized to cause a so called programming effect, where epigenetic changes might result in a long-lasting vulnerability to tobacco use and dependence, manifesting during adolescence or young adulthood. However, previous observational studies show mixed results, perhaps because the association could be influenced by a common genetic predisposition to tobacco use as well as by social factors...

  18. Illness risk and overburden among caregivers of dependent elderly

    OpenAIRE

    Bertel-De la Hoz, Anyel María

    2012-01-01

    Introduction: old age increase the likelihood that health problems arise, whichnecessarily involve greater dependency. The family usually assumes the role of caringfor the elderly, becoming informal caregivers.Objective: to determine the risk of overload and illness among informal caregivers ofdependent elderly.Methodology: this is a descriptive study, which included informal caregivers of elderlypatients attending a program of promotion and prevention of cardiovascular disease in Cartagena, ...

  19. State-Dependent Molecular Dynamics

    Directory of Open Access Journals (Sweden)

    Ciann-Dong Yang

    2014-10-01

    Full Text Available This paper proposes a new mixed quantum mechanics (QM—molecular mechanics (MM approach, where MM is replaced by quantum Hamilton mechanics (QHM, which inherits the modeling capability of MM, while preserving the state-dependent nature of QM. QHM, a single mechanics playing the roles of QM and MM simultaneously, will be employed here to derive the three-dimensional quantum dynamics of diatomic molecules. The resulting state-dependent molecular dynamics including vibration, rotation and spin are shown to completely agree with the QM description and well match the experimental vibration-rotation spectrum. QHM can be incorporated into the framework of a mixed quantum-classical Bohmian method to enable a trajectory interpretation of orbital-spin interaction and spin entanglement in molecular dynamics.

  20. Scheme Dependence and Multiple Couplings

    CERN Document Server

    Jack, Ian

    2016-01-01

    For theories with multiple couplings the perturbative $\\beta$-functions for scalar, Yukawa couplings are expressible in terms of contributions corresponding to one particle irreducible graphs and also contributions which are one particle reducible depending on the anomalous dimension. Here we discuss redefinitions, or changes of scheme, which preserve this structure. The redefinitions allow for IPR contributions of a specific form, as is necessary to encompass the relation between MS and momentum subtraction renormalisation schemes. Many multiply 1PR terms in the transformed $\\beta$-function are generated but these can all be absorbed into antisymmetric contributions to the anomalous dimensions which are essentially arbitrary and can be discarded. As an illustration the results are applied to the scheme dependence of the anomalous dimension, which determines the $\\beta$-function, for ${\\cal N}=1$ supersymmetric scalar fermion theories in four dimensions up to four loops.

  1. Nuclear dependence of charm production

    International Nuclear Information System (INIS)

    Using data taken by SELEX during the 1996-1997 fixed target run at Fermilab, we study the production of charmed hadrons on copper and carbon targets with Σ-, p, π-, and π+ beams. Parametrizing the dependence of the inclusive production cross section on the atomic number A as Aα, we determine α for D+, D0, Ds+, D+(2010), Λc+, and their respective anti-particles, as a function of their transverse momentum pt and scaled longitudinal momentum xF. Within our statistics there is no dependence of α on xF for any charm species for the interval 0.1 Fmeson=0.850±0.028. This is somewhat larger than the corresponding average αbaryon=0.755±0.016 for charm production by baryon beams (Σ-, p). (orig.)

  2. The Copenhagen Dependency Treebank (CDT)

    DEFF Research Database (Denmark)

    Høeg Müller, Henrik; Korzen, Iørn

    2014-01-01

    fundamentals of how CDT is marked up with semantic relations in accordance with the dependency principles governing the annotation on the other levels of CDT. Specifically, focus will be on how Generative Lexicon (GL) theory has been incorporated into the unitary theoretical dependency framework of CDT. An...... annotation scheme for lexical semantics has been designed so as to account for the lexico-semantic structure of complex NPs, and the four GL qualia also appear in some of the CDT discourse relation labels as a description of parallel semantic relations at this level.......The objective of this paper is to provide an overview of the CDT annotation design with special emphasis on the modelling of the interface between the syntactic level and two other linguistic levels, viz. morphology and discourse. In connection with the description of NP annotation we present the...

  3. Spatially dependent electromagnetically induced transparency

    CERN Document Server

    Radwell, Neal; Piccirillo, Bruno; Barnett, Stephen M; Franke-Arnold, Sonja

    2014-01-01

    Recent years have seen vast progress in the generation and detection of structured light, with potential applications in high capacity optical data storage and continuous variable quantum technologies. Here we measure the transmission of structured light through cold rubidium atoms and observe regions of electromagnetically induced transparency (EIT). We use q-plates to generate a probe beam with azimuthally varying phase and polarisation structure, and its right and left circular polarisation components provide the probe and control of an EIT transition. We observe an azimuthal modulation of the absorption profile that is dictated by the phase and polarisation structure of the probe laser. Conventional EIT systems do not exhibit phase sensitivity. We show, however, that a weak transverse magnetic field closes the EIT transitions, thereby generating phase dependent dark states which in turn lead to phase dependent transparency, in agreement with our measurements.

  4. Context-dependent metabolic networks

    CERN Document Server

    Beguerisse-Díaz, Mariano; Oyarzún, Diego; Picó, Jesús; Barahona, Mauricio

    2016-01-01

    Cells adapt their metabolism to survive changes in their environment. We present a framework for the construction and analysis of metabolic reaction networks that can be tailored to reflect different environmental conditions. Using context-dependent flux distributions from Flux Balance Analysis (FBA), we produce directed networks with weighted links representing the amount of metabolite flowing from a source reaction to a target reaction per unit time. Such networks are analyzed with tools from network theory to reveal salient features of metabolite flows in each biological context. We illustrate our approach with the directed network of the central carbon metabolism of Escherichia coli, and study its properties in four relevant biological scenarios. Our results show that both flow and network structure depend drastically on the environment: networks produced from the same metabolic model in different contexts have different edges, components, and flow communities, capturing the biological re-routing of metab...

  5. Direction-dependent exponential biassing

    International Nuclear Information System (INIS)

    When Monte Carlo methods are applied to penetration problems, the use of variance reduction techniques is essential if realistic computing times are to be achieved. A technique known as direction-dependent exponential biassing is described which is simple to apply and therefore suitable for problems with difficult geometry. The material cross section in any region is multiplied by a factor which depends on the particle direction, so that particles travelling in a preferred direction ''see'' a smaller cross section than those travelling in the opposite direction. A theoretical study shows that substantial gains may be obtained, and that the choice of biassing parameter is not critical. The method has been implemented alongside other importance sampling techniques in the general Monte Carlo code SPARTAN, and results obtained for simple problems using this code are included. 4 references. (U.S.)

  6. Contagion and state dependent mutations

    OpenAIRE

    Szeidl, Adam; Lee, In Ho; Valentinyi, Akos

    2000-01-01

    Early results of evolutionary game theory showed that the risk dominant equilibrium is uniquely selected on the long run by the best response dynamics with mutation. Bergin and Lipman (1996) qualified this result by showing that for a given population size the evolutionary process can select any strict Nash equilibrium if the probability of choosing a nonbest reply is state-dependent. This paper shows that the unique selection of the risk dominant equilibrium is robust with respect to state d...

  7. Energy dependence of fission observables

    Science.gov (United States)

    Paşca, Horia

    2016-01-01

    The mass, charge and isotopic distributions of fission fragments are studied within an improved scission-point statistical model in the reaction 235U+n at different energies of the incident neutron. The available experimental data are well reproduced and the energy-dependencies of the observable characteristics of fission are predicted for future experiments. The calculated mass distribution of 238U+n is also compared with experimental data.

  8. Dependence structure of market states

    OpenAIRE

    Desislava Chetalova; Marcel Wollschl\\"ager; Rudi Sch\\"afer

    2015-01-01

    We study the dependence structure of market states by estimating empirical pairwise copulas of daily stock returns. We consider both original returns, which exhibit time-varying trends and volatilities, as well as locally normalized ones, where the non-stationarity has been removed. The empirical pairwise copula for each state is compared with a bivariate K-copula. This copula arises from a recently introduced random matrix model, in which non-stationary correlations between returns are model...

  9. Geographic Luck and Dependency Theory

    Institute of Scientific and Technical Information of China (English)

    Ziheng Liu

    2015-01-01

    Economic disparity is a huge global issue nowadays which threatens the economic justice and thus in some sense decides the fate of human be-ing,especially those from developing countries.This essay analyzes economic disparity by using Geographic Luck and Dependency Theory.None of the two theories could explain the economic disparity individually.China,Britain and Iran are used as three examples to support the thesis.

  10. The psychobiology of nicotine dependence

    OpenAIRE

    D. J. K. Balfour

    2008-01-01

    There is abundant evidence to show that nicotine is the principal addictive component of tobacco smoke. The results of laboratory studies have shown that nicotine has many of the behavioural and neurobiological properties of a drug of dependence. This article focuses on the evidence that nicotine has the rewarding and reinforcing properties typical of an addictive drug and that these properties are mediated, in part, by its effects on mesolimbic dopamine neurones. However, in many experimenta...

  11. Alcohol Dependence, Withdrawal, and Relapse

    OpenAIRE

    Howard C Becker

    2008-01-01

    Continued excessive alcohol consumption can lead to the development of dependence that is associated with a withdrawal syndrome when alcohol consumption is ceased or substantially reduced. This syndrome comprises physical signs as well as psychological symptoms that contribute to distress and psychological discomfort. For some people the fear of withdrawal symptoms may help perpetuate alcohol abuse; moreover, the presence of withdrawal symptoms may contribute to relapse after periods of absti...

  12. Sample Size Dependent Species Models

    OpenAIRE

    Zhou, Mingyuan; Walker, Stephen G.

    2014-01-01

    Motivated by the fundamental problem of measuring species diversity, this paper introduces the concept of a cluster structure to define an exchangeable cluster probability function that governs the joint distribution of a random count and its exchangeable random partitions. A cluster structure, naturally arising from a completely random measure mixed Poisson process, allows the probability distribution of the random partitions of a subset of a sample to be dependent on the sample size, a dist...

  13. Psychobiological mechanisms of exercise dependence

    OpenAIRE

    Hamer, M.; Karageorghis, CI

    2007-01-01

    Exercise dependence (ED) is characterised by an obsessive and unhealthy preoccupation with exercise. Previous research has focused largely on identifying behavioural aspects of ED, although the biological mechanisms remain unknown and are under researched. We review various ED hypotheses including affect regulation, anorexia analogue, sympathetic arousal and β-endorphin. We also present a novel hypothesis pertaining to ED and interleukin (IL)-6, which combines previous hypotheses with literat...

  14. A Dependency Parser for Tweets

    OpenAIRE

    Kong, Lingpeng; Schneider, Nathan; Swayamdipta, Swabha; Bhatia, Archna; Dyer, Chris; Smith, Noah A.

    2014-01-01

    We describe a new dependency parser for English tweets, TWEEBOPARSER. The parser builds on several contributions: new syntactic annotations for a corpus of tweets (TWEEBANK), with conventions informed by the domain; adaptations to a statistical parsing algorithm; and a new approach to exploiting out-of-domain Penn Treebank data. Our experiments show that the parser achieves over 80% unlabeled attachment accuracy on our new, high-quality test set and measure the benefit of our contributions.Ou...

  15. Mutant Generation for Aspect Oriented Programs

    Directory of Open Access Journals (Sweden)

    SHAILENDRA MISHRA

    2010-12-01

    Full Text Available Testing of aspect oriented programs is a new programming paradigm. Many researchers had contributed their research in the field of testing AOP. Mutation testing is an emerging area of research in testing of aspect oriented programming. The effectiveness of mutation testing depends on finding fault types and designing of mutation operators on the basis of faults identified. Therefore the ffectiveness of testing depends upon the quality of these mutation operators. We already have the mutation operators for procedural and object oriented languages, but for aspect oriented language only a few researchers have contributed. In this paper we will study in detail about the fault types and related mutation operators for AspectJ language. This paper also proposes the implementationframework to implement these mutation operators automatically.

  16. Backreaction: Gauge and Frame Dependences

    CERN Document Server

    Brown, Iain A; Coley, Alan

    2012-01-01

    The cosmological backreaction from perturbations is clearly gauge-dependent, and obviously depends on the choice of averaged Hubble rate. We consider two common choices of Hubble rate and advocate the use of comoving volume-preserving gauges. We highlight two examples valid to an appropriate order in perturbation theory, uniform curvature gauge, which is as close to volume-preserving as possible, and a spatially-traceless uniform cold dark matter gauge which preserves the volume to linear order. We demonstrate the strong gauge- and frame-dependences in averaging. In traceless uniform CDM gauge the backreaction exhibits a strong ultra-violet divergence and can be tuned to an arbitrary magnitude with an appropriate choice of smoothing scale. In uniform curvature gauge we find that for a choice of Hubble rate locked to the spatial surface the backreaction vanishes identically, while for a Hubble rate defined from a fluid's expansion scalar the effective energy density at the current epoch in an Einstein-de Sitte...

  17. Metallicity dependence of HMXB populations

    CERN Document Server

    Douna, V M; Mirabel, I F; Pedrosa, S E

    2015-01-01

    High-mass X-ray binaries (HMXBs) might have contributed a non-negligible fraction of the energy feedback to the interstellar and intergalactic media at high redshift, becoming important sources for the heating and ionization history of the Universe. However, the importance of this contribution depends on the hypothesized increase in the number of HMXBs formed in low-metallicity galaxies and in their luminosities. In this work we test the aforementioned hypothesis, and quantify the metallicity dependence of HMXB population properties. We compile from the literature a large set of data on the sizes and X-ray luminosities of HMXB populations in nearby galaxies with known metallicities and star formation rates. We use Bayesian inference to fit simple Monte Carlo models that describe the metallicity dependence of the size and luminosity of the HMXB populations. We find that HMXBs are typically ten times more numerous per unit star formation rate in low-metallicity galaxies (12 + log(O/H) < 8, namely < 20% so...

  18. The CHROME Honors Program

    Science.gov (United States)

    Wilson, Eleanor

    2002-01-01

    The CHROME Honors Program was designed as a two-week residential program for 9th and 1Oth grade students participating in CHROME clubs. The curriculum focused on the health sciences with instruction from: (1) the science and health curriculum of the Dozoretz National Program for Minorities in Applied Sciences (DNIMAS) Program of Norfolk State University (NSU); (2) the humanities curriculum of the NSU Honors Program; (3) NASA-related curriculum in human physiology. An Advisory Committee was formed to work with the Project Coordinator in the design of the summer program.

  19. Revealing the programming process

    DEFF Research Database (Denmark)

    Bennedsen, Jens; Caspersen, Michael Edelgaard

    2005-01-01

    One of the most important goals of an introductory programming course is that the students learn a systematic approach to the development of computer programs. Revealing the programming process is an important part of this; however, textbooks do not address the issue -- probably because...... the textbook medium is static and therefore ill-suited to expose the process of programming. We have found that process recordings in the form of captured narrated programming sessions are a simple, cheap, and efficient way of providing the revelation.We identify seven different elements of the programming...

  20. Maximum a Posteriori Estimation by Search in Probabilistic Programs

    OpenAIRE

    Tolpin, David; Wood, Frank

    2015-01-01

    We introduce an approximate search algorithm for fast maximum a posteriori probability estimation in probabilistic programs, which we call Bayesian ascent Monte Carlo (BaMC). Probabilistic programs represent probabilistic models with varying number of mutually dependent finite, countable, and continuous random variables. BaMC is an anytime MAP search algorithm applicable to any combination of random variables and dependencies. We compare BaMC to other MAP estimation algorithms and show that B...

  1. Analysis Dataset - West Coast Groundfish Observer Program and At-Sea Hake Observer Program data collection, analysis and reporting

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Observer programs are the most comprehensive fishery dependent data collection system for total mortality estimation, protected species monitoring and discard data...

  2. Observer Production (OBSPROD) - West Coast Groundfish Observer Program and At-Sea Hake Observer Program data collection, analysis and reporting

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Observer programs are the most comprehensive fishery dependent data collection system for total mortality estimation, protected species monitoring and discard data...

  3. Observer Logistics (OBSLOG) - West Coast Groundfish Observer Program and At-Sea Hake Observer Program data collection, analysis and reporting

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Observer programs are the most comprehensive fishery dependent data collection system for total mortality estimation, protected species monitoring and discard data...

  4. Path-Dependent Optimal Stochastic Control and Viscosity Solution of Associated Bellman Equations

    OpenAIRE

    Tang, Shanjian; Zhang, Fu

    2012-01-01

    In this paper we study the optimal stochastic control problem for a path-dependent stochastic system under a recursive path-dependent cost functional, whose associated Bellman equation from dynamic programming principle is a path-dependent fully nonlinear partial differential equation of second order. A novel notion of viscosity solutions is introduced. Using Dupire's functional It\\^o calculus, we characterize the value functional of the optimal stochastic control problem as the unique viscos...

  5. Inventory management for dual sales channels with inventory-level-dependent demand

    OpenAIRE

    Tingting Li; Xiaobo Zhao; Jinxing Xie

    2015-01-01

    This paper studies the inventory management problem of dual channels operated by one vendor. Demands of dual channels are inventory-level-dependent. We propose a multi-period stochastic dynamic programming model which shows that under mild conditions, the myopic inventory policy is optimal for the infinite horizon problem. To investigate the importance of capturing demand dependency on inventory levels, we consider a heuristic where the vendor ignores demand dependency on inventory levels, an...

  6. Genetics Home Reference: pyridoxine-dependent epilepsy

    Science.gov (United States)

    ... Home Health Conditions pyridoxine-dependent epilepsy pyridoxine-dependent epilepsy Enable Javascript to view the expand/collapse boxes. ... PDF Open All Close All Description Pyridoxine-dependent epilepsy is a condition that involves seizures beginning in ...

  7. Veterans Choice Program

    Data.gov (United States)

    Department of Veterans Affairs — If you are already enrolled in VA health care, the Choice Program allows you to receive health care within your community. Using this program does NOT impact your...

  8. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... and Canada) International Fellows Associate Fellows Residents Medical Students Affiliate Members Fees and Dues Member Benefits About ... and Canada) International Fellows Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs ...

  9. HUD Program Income Limits

    Data.gov (United States)

    Department of Housing and Urban Development — Income limits used to determine the income eligibility of applicants for assistance under three programs authorized by the National Housing Act. These programs are...

  10. Materials Sciences Programs

    International Nuclear Information System (INIS)

    A compilation and index of the ERDA materials sciences program is presented. This compilation is intended for use by administrators, managers, and scientists to help coordinate research and as an aid in selecting new programs

  11. Materials Sciences Programs

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-01

    A compilation and index of the ERDA materials sciences program is presented. This compilation is intended for use by administrators, managers, and scientists to help coordinate research and as an aid in selecting new programs. (GHT)

  12. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Health System Strategic Partnership ACS Archives Board of Governors Advisory Councils Quality Programs Quality Programs Overview About ... FAQs Newsletters Newsletters Overview Newsletters Overview Board of Governors News The CoC Source Committee on Trauma News ...

  13. Parallel programming with PCN

    Energy Technology Data Exchange (ETDEWEB)

    Foster, I.; Tuecke, S.

    1991-12-01

    PCN is a system for developing and executing parallel programs. It comprises a high-level programming language, tools for developing and debugging programs in this language, and interfaces to Fortran and C that allow the reuse of existing code in multilingual parallel programs. Programs developed using PCN are portable across many different workstations, networks, and parallel computers. This document provides all the information required to develop parallel programs with the PCN programming system. In includes both tutorial and reference material. It also presents the basic concepts that underly PCN, particularly where these are likely to be unfamiliar to the reader, and provides pointers to other documentation on the PCN language, programming techniques, and tools. PCN is in the public domain. The latest version of both the software and this manual can be obtained by anonymous FTP from Argonne National Laboratory in the directory pub/pcn at info.mcs.anl.gov (c.f. Appendix A).

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Communities Military Health System Strategic Partnership ACS Archives Board of Governors Advisory Councils Quality Programs Quality Programs ... Contact and FAQs Newsletters Newsletters Overview Newsletters Overview Board of Governors News The CoC Source Committee on ...

  15. Entrez Programming Utilities

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Entrez Programming Utilities (E-utilities) are a set of eight server-side programs that provide a stable interface into the Entrez query and database system at...

  16. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Medical Professionals Skills Programs Find a Treatment Center Patient Safety Resources About the Patient Education Program The Recovery ... Trauma CME Nora Institute Nora Institute for Surgical Patient Safety Nora Institute for Surgical Patient Safety Advanced Skills ...

  17. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... with quality, comprehensive education. The standardized interactive program has been developed by the American College of Surgeons ( ... Hospital Quality Improvement Package The standardized interactive program has been developed by the American College of Surgeons ( ...

  18. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... and Canada) International Fellows Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection Update Your Profile Scholarships, Fellowships, and Awards ...

  19. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Stereotactic Breast Biopsy Accreditation Program Cancer Program Staff Information Surgeon Specific Registry Surgeon Specific Registry Surgeon Specific Registry Features of the SSR CMS Physician Quality Reporting System MOC Part 4 and Recertification Software and Registration ...

  20. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Other Publications Surgery Workforce Policy Program Current Projects Journal Publications from Surgery Workforce Policy Program AMA House ... the ACS Catalog Find a Product Contribute Education Journal of the American College of Surgeons About JACS ...