AFSC/REFM: Nearshore fish survey in northern Bristol Bay, Alaska, July-August 2009

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The project consisted of a nearshore fish, invertebrate, and habitat survey in northern Bristol Bay, Alaska. A 32-ft. gillnet vessel, the F/V Willow was chartered...

Undergraduate and graduate education in Volcanology at University of Bristol, UK

Science.gov (United States)

Ernst, G.; Mader, H.; Phillips, J.; Lejeune, A.; Sparks, S.

2002-05-01

Volcanology education at Bristol is unique for several reasons. The Bristol group operates within a University Research Centre in Environmental and Geophysical Flows (CEGF), involving over 30 staff-to-PhD-level researchers, centered around close collaboration between 4 depts including Earth Sciences and Applied Maths. The uniquely-multidisciplinary setting supports training in volcanology with strong emphasis on combining field-based physical volcanology, theoretical modelling and simple analogue lab experiments. PhD students gain expertise in at least 2 of these 3 aspects during the PhD. Our dept itself is one of the most multidisciplinary in Earth Sciences and is ranked among the 3 leading ES Depts for its research quality. At dept level, there is a strong focus on understanding physical and chemical processes of magmatic/volcanic systems. Teaching/training of students is thus supported by excellent research, and aims at providing profound insights and practical experience into research. At undergraduate level, key experiences of students include 1.) a week-long field class to textbook-quality field sections on one of the most studied active volcanoes (Santorini, Greece), 2.) an independent project where the aim is to learn about all aspects of research as part of a well-focused study including gaining the experience of producing one potentially-publishable paper, 3.) a hands-on research project centered on using the latest analytical methods to solve a problem - this is most successful for 2 reasons: a.) Bristol hosts the EU Geochemical Facility and coordinates an EU Marie Curie Training Centre and b.) the students operate the instruments themselves (ie. they are not run for them); 4.) fourth-year students are especially challenged on the quantitative front (computer programming, statistical data analyses and hypothesis testing -we have excellent computer labs support for teaching), advanced field work and several independent projects. Students are helped into

Bristol Palin: The Pedagogical Media Spectacle of a Sexual Abstinence Ambassador

Science.gov (United States)

DaoJensen, Thuy

2013-01-01

This paper explores the public political media spectacle of Bristol Palin's teenage pregnancy and her status as a single mother through the lens of a critical feminist discourse analysis. The author explores how cultural anxieties over teenage sexuality and unintended pregnancy in America are constructed when the pregnant teen is the daughter…

Ernest Victor Davey (1888-1957) a mechanical dentist and dentists in North Bristol at the time of the First World War.

Science.gov (United States)

Stephens, Chris

2015-01-01

Ernest Davey practised dentistry in Bristol until 1924 when his lack of a dental qualification restricted him to work as a dental technician. He appears to have served in this capacity in France during the First World War before returning to Bristol in 1919 where he spent the rest of his life.

Hazardous Waste Cleanup: Bristol-Myers Squibb Company Worldwide Medicines in Brunswick, New Jersey

Science.gov (United States)

The Bristol-Myers Squibb Company (BMS) is located at 1 Squibb Drive in New Brunswick, New Jersey. The site has been an active pharmaceutical manufacturing and research and development facility since it began operation by E.R. Squibb and Sons, Inc. in 1907.

Final Project Report, Bristol Bay Native Corporation Wind and Hydroelectric Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Vaught, Douglas J.

2007-03-31

The Bristol Bay Native Corporation (BBNC) grant project focused on conducting nine wind resource studies in eight communities in the Bristol Bay region of southwest Alaska and was administered as a collaborative effort between BBNC, the Alaska Energy Authority, Alaska Village Electric Cooperative, Nushagak Electric Cooperative (NEC), Naknek Electric Association (NEA), and several individual village utilities in the region. BBNC’s technical contact and the project manager for this study was Douglas Vaught, P.E., of V3 Energy, LLC, in Eagle River, Alaska. The Bristol Bay region of Alaska is comprised of 29 communities ranging in size from the hub community of Dillingham with a population of approximately 3,000 people, to a few Native Alaska villages that have a few tens of residents. Communities chosen for inclusion in this project were Dillingham, Naknek, Togiak, New Stuyahok, Kokhanok, Perryville, Clark’s Point, and Koliganek. Selection criteria for conduction of wind resource assessments in these communities included population and commercial activity, utility interest, predicted Class 3 or better wind resource, absence of other sources of renewable energy, and geographical coverage of the region. Beginning with the first meteorological tower installation in October 2003, wind resource studies were completed at all sites with at least one year, and as much as two and a half years, of data. In general, the study results are very promising for wind power development in the region with Class 6 winds measured in Kokhanok; Class 4 winds in New Stuyahok, Clark’s Point, and Koliganek; Class 3 winds in Dillingham, Naknek, and Togiak; and Class 2 winds in Perryville. Measured annual average wind speeds and wind power densities at the 30 meter level varied from a high of 7.87 meters per second and 702 watts per square meter in Kokhanok (Class 6 winds), to a low of 4.60 meters per second and 185 watts per square meter in Perryville (Class 2 winds).

An Assessment of Potential Mining Impacts on Salmon Ecosystems of Bristol Bay, Alaska (Final Report)

Science.gov (United States)

The Bristol Bay watershed in southwestern Alaska supports the largest sockeye salmon fishery in the world, is home to 25 federally recognized tribal governments, and contains large mineral resources. The potential for large-scale mining activities in the watershed has raised conc...

78 FR 63148 - Approval and Promulgation of Implementation Plans; Tennessee; Bristol; 2010 Lead Base Year...

Science.gov (United States)

2013-10-23

... Tennessee, through the Tennessee Department of Environment and Conservation (TDEC) on April 11, 2013. The... per year within the Bristol Area is Exide Technologies Facility, a lead acid battery manufacturing and recycling facility which processes lead and reclaimed lead into batteries for the auto industry. Pursuant to...

Excavations in 2014 at Wade Street, Bristol - a documentary and archaeological analysis

OpenAIRE

Nick Corcos; Kamal Badreshany; Alejandra Gutiérrez; Rachel Heaton; Lorrain Higbee; Sarah Newns; Rachel Tyson

2017-01-01

A staged programme of historical research and archaeological fieldwork, involving a desk-based assessment in 2000 (Smith and Erskine 2000), an evaluation in 2013 (Mason 2013), and an excavation followed by a watching brief in 2014, the latter two by Avon Archaeology Ltd, was undertaken in order to mitigate the archaeological impact of a proposed residential development on a site of 1,260m² at the corner and on the north-west side of Little Anne Street and Wade Street, St Jude’s, Bristol. The ...

Workshop Report from June 8, 2017 at University of Bristol, Life Sciences Building, Tyndall Avenue, UK BS8 1TQ Report of the Synthetic Biology, Politics, and Philosophy Workshop

NARCIS (Netherlands)

Meacham, Darian; Bond, Molly; Reinsborough, Michael

2017-01-01

This report summarises the outputs of a workshop that took place at the University of Bristol, UK, in conjunction with the Social Science Research Group at the University of West England, Bristol and the BrisSynBio Synthetic Biology Research Centre on the 8th June 2017. This report has been adapted

Popular political continuity in urban England, 1867-1918: the case studies of Bristol and Northampton

OpenAIRE

Kidd, Matthew

2016-01-01

This thesis examines the transition between working-class radicalism and labour politics in two provincial English constituencies, Bristol and Northampton, between 1867 and 1918. By combining local case studies with a textual analysis of empirical material and a conceptual approach to ideology, it offers fresh insights into popular political change in late nineteenth- and early twentieth-century Britain. \\ud \\ud Its central argument is that, contrary to the prevailing historiography on labour...

Interobserver agreement between primary graders and an expert grader in the Bristol and Weston diabetic retinopathy screening programme: a quality assurance audit.

Science.gov (United States)

Patra, S; Gomm, E M W; Macipe, M; Bailey, C

2009-08-01

To assess the quality and accuracy of primary grading in the Bristol and Weston diabetic retinopathy screening programme and to set standards for future interobserver agreement reports. A prospective audit of 213 image sets from six fully trained primary graders in the Bristol and Weston diabetic retinopathy screening programme was carried out over a 4-week period. All the images graded by the primary graders were regraded by an expert grader blinded to the primary grading results and the identity of the primary grader. The interobserver agreement between primary graders and the blinded expert grader and the corresponding Kappa coefficient was determined for overall grading, referable, non-referable and ungradable disease. The audit standard was set at 80% for interobserver agreement with a Kappa coefficient of 0.7. The interobserver agreement bettered the audit standard of 80% in all the categories. The Kappa coefficient was substantial (0.7) for the overall grading results and ranged from moderate to substantial (0.59-0.65) for referable, non-referable and ungradable disease categories. The main recommendation of the audit was to provide refresher training for the primary graders with focus on ungradable disease. The audit demonstrated an acceptable level of quality and accuracy of primary grading in the Bristol and Weston diabetic retinopathy screening programme and provided a standard against which future interobserver agreement can be measured for quality assurance within a screening programme. Diabet. Med. 26, 820-823 (2009).

Environmental Sensitivity Index (ESI) Atlas: Alaska, Prince William Sound-2000, Aleutians-2001, Bristol Bay-2004, maps and geographic information systems data (NODC Accession 0014162)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Alaska; Prince William Sound (2000), Aleutians (2001), and Bristol Bay (2004). ESI data...

Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative.

Science.gov (United States)

Pencina, Michael J; Louzao, Darcy M; McCourt, Brian J; Adams, Monique R; Tayyabkhan, Rehbar H; Ronco, Peter; Peterson, Eric D

2016-02-01

There are growing calls for sponsors to increase transparency by providing access to clinical trial data. In response, Bristol-Myers Squibb and the Duke Clinical Research Institute have collaborated on a new initiative, Supporting Open Access to Researchers. The aim is to facilitate open sharing of Bristol-Myers Squibb trial data with interested researchers. Key features of the Supporting Open Access to Researchers data sharing model include an independent review committee that ensures expert consideration of each proposal, stringent data deidentification/anonymization and protection of patient privacy, requirement of prespecified statistical analysis plans, and independent review of manuscripts before submission for publication. We believe that these approaches will promote open science by allowing investigators to verify trial results as well as to pursue interesting secondary uses of trial data without compromising scientific integrity. Copyright © 2015 Elsevier Inc. All rights reserved.

The Bristol University neutron dosimetry system

International Nuclear Information System (INIS)

Worley, A.; Fews, A.P.; Henshaw, D.L.

1987-01-01

The neutron dosimetry system developed at Bristol is based on recording recoil proton tracks in conventionally etched PADC plastic using a fully automated image analysis system. Two features contribute to the achievement of a low dose threshold: high quality plastic is manufactured and undergoes extensive quality control tests prior to acceptance for use in dosimetry, and a readout system with high efficiency for rejecting background events is used. The principal dosemeter that has been developed consists of three orthogonal elements, each containing two 3 cm x 1 cm plastics on either side of a polyethylene radiator. On each plastic an area of 0.15 cm 2 is scanned giving a total active area of 0.90 cm 2 . Each plastic is coded for manual identification and for computer recognition. The track counts from the six plastics are added with different weightings to achieve a measure of dose which is independent of irradiation direction when worn on the body. The device has been calibrated using monoenergetic neutrons in the range 100 keV to 14.7 MeV at NPL, and using the recent CENDOS exposure. If the track counts are added without weighting, the device has a nominal response of 120 tracks cm -2 .mSv -1 and an energy threshold at 200 keV. Taken together with a background of 20 track cm -2 , a dose threshold of around 80μSv is implied. A simpler dosemeter, using a single plastic/radiator combination, may also be considered. If a 1 cm 2 device is used for normal incidence exposure, the dose threshold is calculated to be 25 μSv. (author)

The BRIDGE HadCM3 family of climate models: HadCM3@Bristol v1.0

Science.gov (United States)

Valdes, Paul J.; Armstrong, Edward; Badger, Marcus P. S.; Bradshaw, Catherine D.; Bragg, Fran; Crucifix, Michel; Davies-Barnard, Taraka; Day, Jonathan J.; Farnsworth, Alex; Gordon, Chris; Hopcroft, Peter O.; Kennedy, Alan T.; Lord, Natalie S.; Lunt, Dan J.; Marzocchi, Alice; Parry, Louise M.; Pope, Vicky; Roberts, William H. G.; Stone, Emma J.; Tourte, Gregory J. L.; Williams, Jonny H. T.

2017-10-01

Understanding natural and anthropogenic climate change processes involves using computational models that represent the main components of the Earth system: the atmosphere, ocean, sea ice, and land surface. These models have become increasingly computationally expensive as resolution is increased and more complex process representations are included. However, to gain robust insight into how climate may respond to a given forcing, and to meaningfully quantify the associated uncertainty, it is often required to use either or both ensemble approaches and very long integrations. For this reason, more computationally efficient models can be very valuable tools. Here we provide a comprehensive overview of the suite of climate models based around the HadCM3 coupled general circulation model. This model was developed at the UK Met Office and has been heavily used during the last 15 years for a range of future (and past) climate change studies, but has now been largely superseded for many scientific studies by more recently developed models. However, it continues to be extensively used by various institutions, including the BRIDGE (Bristol Research Initiative for the Dynamic Global Environment) research group at the University of Bristol, who have made modest adaptations to the base HadCM3 model over time. These adaptations mean that the original documentation is not entirely representative, and several other relatively undocumented configurations are in use. We therefore describe the key features of a number of configurations of the HadCM3 climate model family, which together make up HadCM3@Bristol version 1.0. In order to differentiate variants that have undergone development at BRIDGE, we have introduced the letter B into the model nomenclature. We include descriptions of the atmosphere-only model (HadAM3B), the coupled model with a low-resolution ocean (HadCM3BL), the high-resolution atmosphere-only model (HadAM3BH), and the regional model (HadRM3B). These also include

The Career Intentions, Work-Life Balance and Retirement Plans of Dental Undergraduates at the University of Bristol

OpenAIRE

Puryer, James; Patel, Ashini

2016-01-01

Aim: To investigate the career intentions, work-life balance and retirement plans of dental undergraduates at the University of Bristol in 2015. Method: Cross-sectional survey of 210 clinical undergraduates using an anonymous self-report questionnaire.Results: The response rate was 79%. The majority (81.7%) were ‘satisfied’ or ‘extremely satisfied’ with their choice of career. The majority (78.7%) felt men and women are equally likely to succeed in dentistry, although 42.9% felt men had an ad...

Seasonal marine growth of Bristol Bay sockeye salmon (Oncorhynchus nerka) in relation to competition with Asian pink salmon (O. gorbuscho) and the 1977 ocean regime shift

Science.gov (United States)

Ruggerone, Gregory T.; Farley, Ed; Nielsen, Jennifer L.; Hagen, Peter

2005-01-01

Recent research demonstrated significantly lower growth and survival of Bristol Bay sockeye salmon (Oncorhynchus nerka) during odd-numbered years of their second or third years at sea (1975, 1977, etc.), a trend that was opposite that of Asian pink salmon (O. gorbuscha) abundance. Here we evaluated seasonal growth trends of Kvichak and Egegik river sockeye salmon (Bristol Bay stocks) during even- and odd-numbered years at sea by measuring scale circuli increments within each growth zone of each major salmon age group between 1955 and 2000. First year scale growth was not significantly different between odd- and even-numbered years, but peak growth of age-2. smolts was significantly higher than age-1 smolts. Total second and third year scale growth of salmon was significantly lower during odd- than during even-numbered years. However, reduced scale growth in odd-numbered years began after peak growth in spring and continued through summer and fall even though most pink salmon had left the high seas by late July (10-18% growth reduction in odd vs. even years). The alternating odd and even year growth pattern was consistent before and after the 1977 ocean regime shift. During 1977-2000, when salmon abundance was relatively great, sockeye salmon growth was high during specific seasons compared with that during 1955-1976, that is to say, immediately after entry to Bristol Bay, after peak growth in the first year, during the middle of the second growing season, and during spring of the third season. Growth after the spring peak in the third year at sea was relatively low during 1977-2000. We hypothesize that high consumption rates of prey by pink salmon during spring through mid-July of odd-numbered years, coupled with declining zooplankton biomass during summer and potentially cyclic abundances of squid and other prey, contributed to reduced prey availability and therefore reduced growth of Bristol Bay sockeye salmon during late spring through fall of odd-numbered years.

Resilience and Social Justice as the Basis for Urban Food System Reform - A Case Study of Bristol, U.K.

OpenAIRE

Wilson, Mark

2014-01-01

This paper considers the contribution of urban agriculture to the local food system and the role of the city council in this system. Using an interdisciplinary mixed method approach, the study explores local stakeholders’ perspectives of these aspects in the city of Bristol, UK. The findings were viewed through the lenses of two conceptual frameworks, resilience and social justice. The results reveal that urban agriculture increases resilience through building community, maintaining a diverse...

Origins and early days of the Bristol school of cosmic-ray physics

International Nuclear Information System (INIS)

Lock, W.O.

1990-01-01

The founder of the Bristol School was Cecil Frank Powell, Nobel Laureate for Physics in 1950 for his discovery of the pi-meson and sometimes called the father of meson physics. The article describes first his early life and his many years of systematic work to perfect the nuclear emulsion technique. This is followed by a brief description of the circumstances of the discovery of the pi-meson and of the so-called 'strange particles'. An attempt is made to give a portrait of Powell and to explain his success in building up one of the first post-war international research teams, which paved the way for large international laboratories such as CERN. The account concludes with some personal memories of the award of the Nobel Prize and of the happy and creative atmosphere which Powell created around him at one of the most exciting times in the physics of cosmic rays since their discovery just after the beginning of the century. (author)

The BRIDGE HadCM3 family of climate models: HadCM3@Bristol v1.0

Directory of Open Access Journals (Sweden)

P. J. Valdes

2017-10-01

Full Text Available Understanding natural and anthropogenic climate change processes involves using computational models that represent the main components of the Earth system: the atmosphere, ocean, sea ice, and land surface. These models have become increasingly computationally expensive as resolution is increased and more complex process representations are included. However, to gain robust insight into how climate may respond to a given forcing, and to meaningfully quantify the associated uncertainty, it is often required to use either or both ensemble approaches and very long integrations. For this reason, more computationally efficient models can be very valuable tools. Here we provide a comprehensive overview of the suite of climate models based around the HadCM3 coupled general circulation model. This model was developed at the UK Met Office and has been heavily used during the last 15 years for a range of future (and past climate change studies, but has now been largely superseded for many scientific studies by more recently developed models. However, it continues to be extensively used by various institutions, including the BRIDGE (Bristol Research Initiative for the Dynamic Global Environment research group at the University of Bristol, who have made modest adaptations to the base HadCM3 model over time. These adaptations mean that the original documentation is not entirely representative, and several other relatively undocumented configurations are in use. We therefore describe the key features of a number of configurations of the HadCM3 climate model family, which together make up HadCM3@Bristol version 1.0. In order to differentiate variants that have undergone development at BRIDGE, we have introduced the letter B into the model nomenclature. We include descriptions of the atmosphere-only model (HadAM3B, the coupled model with a low-resolution ocean (HadCM3BL, the high-resolution atmosphere-only model (HadAM3BH, and the regional model (HadRM3B

Dtags beluga whale data collected from Bristol Bay by Alaska Fisheries Scientific Center, National Marine Mammal Laboratory from 2011-05-01 to 2014-08-31 (NCEI Accession 0142174)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Suction cup attached multi-sensor tags were placed on beluga whales in Bristol Bay, Alaska, to collect depth, 3D acceleration and sound. Data were coupled with...

A model to predict the level of artificial radionuclides in environmental materials in the Severn Estuary and the Bristol Channel

International Nuclear Information System (INIS)

McColl, N.P.

1988-01-01

The NRPB SEVERN compartment model, of the Bristol Channel and Severn Estuary, has been developed for used in predicting environmental concentrations of artificial radionuclides present in the estuary. A comparison between predicted and measured values of salinity and environmental 137 Cs concentrations has demonstrated the overall validity of the model. SEVERN has been used to assess the radiological impact of radionuclides present in the estuary which result from low-level routine discharges from the nuclear power industry. (author)

Nearshore fish survey in northern Bristol Bay, Alaska conducted from 2009-07 to 2009-08 by Alaska Fisheries Science Center, Resource Ecology and Fisheries Management division (NCEI Accession 0144625)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The project consisted of a nearshore fish, invertebrate, and habitat survey in northern Bristol Bay, Alaska. A 32-ft. gillnet vessel, the F/V Willow was chartered...

The development of immunomodulatory monoclonal antibodies as a new therapeutic modality for cancer: the Bristol-Myers Squibb experience.

Science.gov (United States)

Berman, David; Korman, Alan; Peck, Ronald; Feltquate, David; Lonberg, Nils; Canetta, Renzo

2015-04-01

The discovery and increased understanding of the complex interactions regulating the immune system have contributed to the pharmacologic activation of antitumor immunity. The activity of effector cells, such as T and NK cells, is regulated by an array of activating and attenuating receptors and ligands. Agents that target these molecules can modulate immune responses by exerting antagonistic or agonistic effects. Several T- or NK-cell modulators have entered clinical trials, and two have been approved for use. Ipilimumab (Yervoy®, Bristol-Myers Squibb) and nivolumab (OPDIVO, Ono Pharmaceutical Co., Ltd./Bristol-Myers Squibb) were approved for the treatment of metastatic melanoma, in March 2011 in the United States, and in July 2014 in Japan, respectively. The clinical activity of these two antibodies has not been limited to tumor types considered sensitive to immunotherapy, and promising activity has been reported in other solid and hematologic tumors. Clinical development of ipilimumab and nivolumab has presented unique challenges in terms of safety and efficacy, requiring the establishment of new evaluation criteria for adverse events and antitumor effects. Guidelines intended to help oncologists properly manage treatment in view of these non-traditional features have been implemented. The introduction of this new modality of cancer treatment, which is meant to integrate with or replace the current standards of care, requires additional efforts in terms of optimization of treatment administration, identification of biomarkers and application of new clinical trial designs. The availability of immune modulators with different mechanisms of action offers the opportunity to establish immunological combinations as new standards of care. Copyright © 2014 Elsevier Inc. All rights reserved.

The Bristol Stool Form Scale: its translation to Portuguese, cultural adaptation and validation Traducción, adaptación cultural y validación de la "Bristol Stool Form Scale" Tradução, adaptação cultural e validação da Bristol Stool Form Scale para a população brasileira

Directory of Open Access Journals (Sweden)

Anna Paula Martinez

2012-06-01

Full Text Available The Bristol Stool Form Scale is used for describing feces. The objective of this research was its translation, cultural adaptation and validation for Brazil. The methodology was translation, back-translation and discussion. Validation involved 85 nurses, 80 doctors, and 80 patients, who correlated images of seven types of feces with the descriptions. Results: there was a difference in sex distribution, with males predominating among the doctors and females among nurses and patients. In relation to concordance between definitions and pictures, the highest percentage was in type 5 in all three groups and the lowest was in types 6 and 7 for the doctors, in type 3 for the nurses, and type 6 for the patients. The general Kappa index was 0.826. Conclusion: the scale demonstrated high reliability for all the groups studied.La "Bristol Stool Form Scale" es usada para describir las heces. Objetivo: traducción, adaptación cultural y la validación para ser utilizada en Brasil. Metodología: Fue realizada la traducción, la traducción inversa y la discusión final. Para validar, se incluyeron 85 enfermeros y 80 médicos y pacientes que correlacionaron diseños de siete tipos de heces con descripciones. Resultados - Hubo diferencia en cuanto a la distribución del sexo con predominio masculino entre los médicos y femenino para los enfermeros y pacientes. Con respecto a la concordancia entre los conceptos y las imágenes, la mayor concordancia fue del tipo 5 en cuanto que el de menor correspondencia para los médicos fueron los tipos 6 y 7, para los enfermeros el 3 y el 6 para los pacientes. El índice de Kappa general fue de 0,826. Conclusión: Los valores obtenidos demuestran la alta confiabilidad de este cuestionario con respecto a los grupos estudiados.A Escala de Bristol para Consistência de Fezes é usada na descrição de fezes. O objetivo deste estudo foi realizar a tradução, adaptação cultural e validação para o Brasil, dessa escala. Como

Case study: technology initiative led to advanced lead optimization screening processes at Bristol-Myers Squibb, 2004-2009.

Science.gov (United States)

Zhang, Litao; Cvijic, Mary Ellen; Lippy, Jonathan; Myslik, James; Brenner, Stephen L; Binnie, Alastair; Houston, John G

2012-07-01

In this paper, we review the key solutions that enabled evolution of the lead optimization screening support process at Bristol-Myers Squibb (BMS) between 2004 and 2009. During this time, technology infrastructure investment and scientific expertise integration laid the foundations to build and tailor lead optimization screening support models across all therapeutic groups at BMS. Together, harnessing advanced screening technology platforms and expanding panel screening strategy led to a paradigm shift at BMS in supporting lead optimization screening capability. Parallel SAR and structure liability relationship (SLR) screening approaches were first and broadly introduced to empower more-rapid and -informed decisions about chemical synthesis strategy and to broaden options for identifying high-quality drug candidates during lead optimization. Copyright © 2012 Elsevier Ltd. All rights reserved.

Aerodynamics of Hypersonic Lifting Vehicles: Conference Proceedings Held at the Fluid Dynamics Panel Symposium in Bristol, United Kingdom on 6-9 April 1987

Science.gov (United States)

1987-11-01

8217Cone drag in the transition from continuum to free molecular flow.’ PhD Thesis, Jesus College, Oxford (1984) 10-9 6i ______3&14 445 105.47 rn,=2.93...9D so 707 60 Shttle 40 1 2 3 4 S 6 7 8 SPEED (W~.) FIGURE 2 Re-entry trajectories 34-6 Bom off- Gi Perlonunce SbWWcura Materia FIGURE 3 The...outstanding hospitality at the reception Monday evening. In addition, I thank the University of Bristol for providing the local arrangements for the

The Bristol Radiology Report Assessment Tool (BRRAT): Developing a workplace-based assessment tool for radiology reporting skills

International Nuclear Information System (INIS)

Wallis, A.; Edey, A.; Prothero, D.; McCoubrie, P.

2013-01-01

Aim: To review the development of a workplace-based assessment tool to assess the quality of written radiology reports and assess its reliability, feasibility, and validity. Materials and methods: A comprehensive literature review and rigorous Delphi study enabled the development of the Bristol Radiology Report Assessment Tool (BRRAT), which consists of 19 questions and a global assessment score. Three assessors applied the assessment tool to 240 radiology reports provided by 24 radiology trainees. Results: The reliability coefficient for the 19 questions was 0.79 and the equivalent coefficient for the global assessment scores was 0.67. Generalizability coefficients demonstrate that higher numbers of assessors and assessments are needed to reach acceptable levels of reliability for summative assessments due to assessor subjectivity. Conclusion: The study methodology gives good validity and strong foundation in best-practice. The assessment tool developed for radiology reporting is reliable and most suited to formative assessments

Process evaluation of the Bristol girls dance project

Directory of Open Access Journals (Sweden)

S. J. Sebire

2016-04-01

Full Text Available Abstract Background The Bristol Girls Dance Project was a cluster randomised controlled trial that aimed to increase objectively measured moderate-to-vigorous physical activity (MVPA levels of Year 7 (age 11–12 girls through a dance-based after-school intervention. The intervention was delivered in nine schools and consisted of up to forty after-school dance sessions. This paper reports on the main findings from the detailed process evaluation that was conducted. Methods Quantitative and qualitative data were collected from intervention schools. Dose and fidelity were reported by dance instructors at every session. Intervention dose was defined as attending two thirds of sessions and was measured by attendance registers. Fidelity to the intervention manual was reported by dance instructors. On four randomly-selected occasions, participants reported their perceived level of exertion and enjoyment. Reasons for non-attendance were self-reported at the end of the intervention. Semi-structured interviews were conducted with all dance instructors who delivered the intervention (n = 10 and school contacts (n = 9 in intervention schools. A focus group was conducted with girls who participated in each intervention school (n = 9. Results The study did not affect girls’ MVPA. An average of 31.7 girls participated in each school, with 9.1 per school receiving the intervention dose. Mean attendance and instructors’ fidelity to the intervention manual decreased over time. The decline in attendance was largely attributed to extraneous factors common to after-school activities. Qualitative data suggest that the training and intervention manual were helpful to most instructors. Participant ratings of session enjoyment were high but perceived exertion was low, however, girls found parts of the intervention challenging. Conclusions The intervention was enjoyed by participants. Attendance at the intervention sessions was low but typical of after

The missing history of Bohm's hidden variables theory: The Ninth Symposium of the Colston Research Society, Bristol, 1957

Science.gov (United States)

Kožnjak, Boris

2018-05-01

In this paper, I analyze the historical context, scientific and philosophical content, and the implications of the thus far historically largely neglected Ninth Symposium of the Colston Research Society held in Bristol at the beginning of April 1957, the first major international event after World War II gathering eminent physicists and philosophers to discuss the foundational questions of quantum mechanics, in respect to the early reception of the causal quantum theory program mapped and defended by David Bohm during the five years preceding the Symposium. As will be demonstrated, contrary to the almost unanimously negative and even hostile reception of Bohm's ideas on hidden variables in the early 1950s, in the close aftermath of the 1957 Colston Research Symposium Bohm's ideas received a more open-minded and ideologically relaxed critical rehabilitation, in which the Symposium itself played a vital and essential part.

The revised Bristol Rheumatoid Arthritis Fatigue measures and the Rheumatoid Arthritis Impact of Disease scale: validation in six countries.

Science.gov (United States)

Hewlett, Sarah; Kirwan, John; Bode, Christina; Cramp, Fiona; Carmona, Loreto; Dures, Emma; Englbrecht, Matthias; Fransen, Jaap; Greenwood, Rosemary; Hagel, Sofia; van de Laar, Maart; Molto, Anna; Nicklin, Joanna; Petersson, Ingemar F; Redondo, Marta; Schett, Georg; Gossec, Laure

2018-02-01

To evaluate the Bristol Rheumatoid Arthritis Fatigue Multidimensional Questionnaire (BRAF-MDQ), the revised Bristol Rheumatoid Arthritis Numerical Rating Scales (BRAF-NRS V2) and the Rheumatoid Arthritis Impact of Disease (RAID) scale in six countries. We surveyed RA patients in France, Germany, The Netherlands, Spain, Sweden and the UK, including the HAQ, 36-item Short Form Health Survey (SF-36) and potential revisions of the BRAF-NRS coping and Spanish RAID coping items. Factor structure and internal consistency were examined by factor analysis and Cronbach's α and construct validity by Spearman's correlation. A total of 1276 patients participated (76% female, 25% with a disease duration <5 years, median HAQ 1.0). The original BRAF-MDQ four-factor structure and RAID single-factor structure were confirmed in every country with ⩾66% of variation in items explained by each factor and all item factor loadings of 0.71-0.98. Internal consistency for the BRAF-MDQ total and subscales was a Cronbach's α of 0.75-0.96 and for RAID, 0.93-0.96. Fatigue construct validity was shown for the BRAF-MDQ and BRAF-NRS severity and effect scales, correlated internally with SF-36 vitality and with RAID fatigue (r = 0.63-0.93). Broader construct validity for the BRAFs and RAID was shown by correlation with each other, HAQ and SF-36 domains (r = 0.46-0.82), with similar patterns in individual countries. The revised BRAF-NRS V2 Coping item had stronger validity than the original in all analyses. The revised Spanish RAID coping item performed as well as the original. Across six European countries, the BRAF-MDQ identifies the same four aspects of fatigue, and along with the RAID, shows strong factor structure and internal consistency and moderate-good construct validity. The revised BRAF-NRS V2 shows improved construct validity and replaces the original. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology.

The Bristol Radiology Report Assessment Tool (BRRAT): developing a workplace-based assessment tool for radiology reporting skills.

Science.gov (United States)

Wallis, A; Edey, A; Prothero, D; McCoubrie, P

2013-11-01

To review the development of a workplace-based assessment tool to assess the quality of written radiology reports and assess its reliability, feasibility, and validity. A comprehensive literature review and rigorous Delphi study enabled the development of the Bristol Radiology Report Assessment Tool (BRRAT), which consists of 19 questions and a global assessment score. Three assessors applied the assessment tool to 240 radiology reports provided by 24 radiology trainees. The reliability coefficient for the 19 questions was 0.79 and the equivalent coefficient for the global assessment scores was 0.67. Generalizability coefficients demonstrate that higher numbers of assessors and assessments are needed to reach acceptable levels of reliability for summative assessments due to assessor subjectivity. The study methodology gives good validity and strong foundation in best-practice. The assessment tool developed for radiology reporting is reliable and most suited to formative assessments. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Development and initial validation of the Bristol Impact of Hypermobility questionnaire.

Science.gov (United States)

Palmer, S; Cramp, F; Lewis, R; Gould, G; Clark, E M

2017-06-01

Stage 1 - to identify the impact of joint hypermobility syndrome (JHS) on adults; Stage 2 - to develop a questionnaire to assess the impact of JHS; and Stage 3 - to undertake item reduction and establish the questionnaire's concurrent validity. A mixed methods study employing qualitative focus groups and interviews (Stage 1); a working group of patients, clinicians and researchers, and 'think aloud' interviews (Stage 2); and quantitative analysis of questionnaire responses (Stage 3). Stages 1 and 2 took place in one secondary care hospital in the UK. Members of a UK-wide patient organisation were recruited in Stage 3. In total, 15, four and 615 participants took part in Stages 1, 2 and 3, respectively. Inclusion criteria were: age ≥18 years; diagnosis of JHS; no other conditions affecting physical function; able to give informed consent; and able to understand and communicate in English. None. The development of a questionnaire to assess the impact of JHS. Stage 1 identified a wide range of impairments, activity limitations and participation restrictions In Stage 2, a draft questionnaire was developed and refined following 'think aloud' analysis, leaving 94 scored items. In Stage 3, items were removed on the basis of low severity and/or high correlation with other items. The final Bristol Impact of Hypermobility (BIoH) questionnaire had 55 scored items, and correlated well with the physical component score of the Short Form 36 health questionnaire (r=-0.725). The BIoH questionnaire demonstrated good concurrent validity. Further psychometric properties need to be established. Copyright © 2016 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

A comparison of three self-tuning control algorithms developed for the Bristol-Babcock controller

International Nuclear Information System (INIS)

Tapp, P.A.

1992-04-01

A brief overview of adaptive control methods relating to the design of self-tuning proportional-integral-derivative (PID) controllers is given. The methods discussed include gain scheduling, self-tuning, auto-tuning, and model-reference adaptive control systems. Several process identification and parameter adjustment methods are discussed. Characteristics of the two most common types of self-tuning controllers implemented by industry (i.e., pattern recognition and process identification) are summarized. The substance of the work is a comparison of three self-tuning proportional-plus-integral (STPI) control algorithms developed to work in conjunction with the Bristol-Babcock PID control module. The STPI control algorithms are based on closed-loop cycling theory, pattern recognition theory, and model-based theory. A brief theory of operation of these three STPI control algorithms is given. Details of the process simulations developed to test the STPI algorithms are given, including an integrating process, a first-order system, a second-order system, a system with initial inverse response, and a system with variable time constant and delay. The STPI algorithms' performance with regard to both setpoint changes and load disturbances is evaluated, and their robustness is compared. The dynamic effects of process deadtime and noise are also considered. Finally, the limitations of each of the STPI algorithms is discussed, some conclusions are drawn from the performance comparisons, and a few recommendations are made. 6 refs

Excavations in 2014 at Wade Street, Bristol - a documentary and archaeological analysis

Directory of Open Access Journals (Sweden)

Nick Corcos

2017-07-01

Full Text Available A staged programme of historical research and archaeological fieldwork, involving a desk-based assessment in 2000 (Smith and Erskine 2000, an evaluation in 2013 (Mason 2013, and an excavation followed by a watching brief in 2014, the latter two by Avon Archaeology Ltd, was undertaken in order to mitigate the archaeological impact of a proposed residential development on a site of 1,260m² at the corner and on the north-west side of Little Anne Street and Wade Street, St Jude’s, Bristol. The site was formerly occupied by residential dwellings, originally established in the very early 18th century as part of a then newly planned development of artisans’ houses. In combination, the data from these studies indicate that the Wade Street site has a history of continuous occupation, from c. 1700 until the buildings on it were removed in the years on either side of the Second World War as part of a so-called 'slum clearance' project. A very small assemblage of medieval pottery recovered from the lower contexts of the site during the excavation hints at some level of activity in the vicinity during the medieval period. This publication offers an opportunity to link the results of the fieldwork to an outline study of a sample of the 19th-century census records, to give a picture of the social dynamics of a highly diverse community in the second half of that century, and which presents a surprisingly mixed picture of both long stability, and incessant change in terms of the movement of people into and out of this part of Wade Street.

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2012-09-13 to 2012-09-25 (NCEI Accession 0157385)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157385 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2013-09-10 to 2013-10-02 (NCEI Accession 0157366)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157366 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2013-05-08 to 2013-05-28 (NCEI Accession 0157373)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157373 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2013-04-19 to 2013-05-08 (NCEI Accession 0157305)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157305 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2012-09-27 to 2012-10-04 (NCEI Accession 0157267)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157267 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2013-02-03 to 2013-02-13 (NCEI Accession 0157382)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157382 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from CEFAS ENDEAVOUR in the Bristol Channel, English Channel and others from 2012-10-23 to 2012-11-09 (NCEI Accession 0157241)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0157241 includes Surface underway, chemical, meteorological and physical data collected from CEFAS ENDEAVOUR in the Bristol Channel, English Channel,...

Sea level rise in the Severn Estuary and Bristol Channel and impacts of a Severn Barrage

Science.gov (United States)

Ahmadian, Reza; Olbert, Agnieszka I.; Hartnett, Michael; Falconer, Roger A.

2014-05-01

Many research projects in recent years have focused on marine renewable energy devices and structures due to the growing interest in marine renewable energy. These devices and structures have very different life spans. Schemes such as the Severn Barrage in the UK, as originally proposed by the Severn Tidal Power Group (STPG), would be the largest tidal renewable energy generation project in the world and would be operational for well over a century if built. Due to the long working life of some of these marine renewable energy schemes, it is important to study the impacts of climate change on such schemes, and particularly sea level rise. This study focuses on investigating the impacts of sea level rise due to climate change on the largest macro-tidal estuary in the UK, namely the Severn Estuary and Bristol Channel, and the alterations of the impacts and the performance of the Severn Barrage as a result of climate change. A hierarchy of computer models was implemented to identify the more localised impacts of climate change in the region of the study. Moreover, the potential benefits of the barrage on reducing flood risk, as well as the impact of climate change and the barrage on intertidal mudflats were investigated. The model predictions showed that the barrage would reduce flood risk due to the sea level rise. Furthermore, annual power output and the initial reduction in flood risk of the barrage would not be affected by sea level rise.

Hydrologic Alterations from Climate Change Inform Assessment of Ecological Risk to Pacific Salmon in Bristol Bay, Alaska.

Directory of Open Access Journals (Sweden)

Cameron Wobus

Full Text Available We developed an integrated hydrologic model of the upper Nushagak and Kvichak watersheds in the Bristol Bay region of southwestern Alaska, a region under substantial development pressure from large-scale copper mining. We incorporated climate change scenarios into this model to evaluate how hydrologic regimes and stream temperatures might change in a future climate, and to summarize indicators of hydrologic alteration that are relevant to salmon habitat ecology and life history. Model simulations project substantial changes in mean winter flow, peak flow dates, and water temperature by 2100. In particular, we find that annual hydrographs will no longer be dominated by a single spring thaw event, but will instead be characterized by numerous high flow events throughout the winter. Stream temperatures increase in all future scenarios, although these temperature increases are moderated relative to air temperatures by cool baseflow inputs during the summer months. Projected changes to flow and stream temperature could influence salmon through alterations in the suitability of spawning gravels, changes in the duration of incubation, increased growth during juvenile stages, and increased exposure to chronic and acute temperature stress. These climate-modulated changes represent a shifting baseline in salmon habitat quality and quantity in the future, and an important consideration to adequately assess the types and magnitude of risks associated with proposed large-scale mining in the region.

Evidence for declining levels of heavy-metals in the Severn Estuary and Bristol Channel, U.K. and their spatial distribution in sediments

International Nuclear Information System (INIS)

Duquesne, Sabine; Newton, Lyn C.; Giusti, Lorenzo; Marriott, Susan B.; Staerk, Hans-Joachim; Bird, David J.

2006-01-01

Levels of heavy-metals (Cd, Cu, Cr, Ni, Pb and Zn) in suspended particulate and in surface and subsurface sediments were determined at seven locations in the Severn Estuary and Bristol Channel. Sediment metal concentrations were highest at sites close to industrial centres but levels have decreased significantly over the last 30 years so that they are now close to, or meet, environmental quality guidelines. The greatest metal concentrations in deposited sediments were usually associated with the finest particulates at locations with muddy sediments, but this was not always true at sites with predominantly sandy sediments. The metals bound to suspended particulates at all sites were remarkably consistent, presumably reflecting the mixing capacity of this macro-tidal estuary. The re-exposure of older, more contaminated sediments could explain the observed differences between deposited and suspended material. Sediment redistribution due to strong seasonal currents might also explain the differences between winter and summer samples. - Heavy-metal contamination in Severn Estuary sediments is declining but shows seasonal variation and depends on location and sediment type

Randomised controlled trial of effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux: Bristol helicobacter project

Science.gov (United States)

Harvey, Richard F; Lane, J Athene; Murray, Liam J; Harvey, Ian M; Donovan, Jenny L; Nair, Prakash

2004-01-01

Objectives To investigate the effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux. Design Cross sectional study, followed by a randomised placebo controlled trial. Setting Seven general practices in Bristol, England. Participants 10 537 people, aged 20-59 years, with and without H pylori infection (determined by the 13C-urea breath test). Main outcome measures Prevalence of heartburn and gastro-oesophageal acid reflux at baseline and two years after treatment to eradicate H pylori infection. Results At baseline, H pylori infection was associated with increased prevalence of heartburn (odds ratio 1.14, 95% confidence interval 1.05 to 1.23) but not reflux (1.05, 0.97 to 1.14). In participants with H pylori infection, active treatment had no effect on the overall prevalence of heartburn (0.99, 0.88 to 1.12) or reflux (1.04, 0.91 to 1.19) and did not improve pre-existing symptoms of heartburn or reflux. Conclusions H pylori infection is associated with a slightly increased prevalence of heartburn but not reflux. Treatment to eradicate H pylori has no net benefit in patients with heartburn or gastro-oesophageal reflux. PMID:15126313

Test-retest reliability and smallest detectable change of the Bristol Impact of Hypermobility (BIoH) questionnaire.

Science.gov (United States)

Palmer, S; Manns, S; Cramp, F; Lewis, R; Clark, E M

2017-12-01

The Bristol Impact of Hypermobility (BIoH) questionnaire is a patient-reported outcome measure developed in conjunction with adults with Joint Hypermobility Syndrome (JHS). It has demonstrated strong concurrent validity with the Short Form-36 (SF-36) physical component score but other psychometric properties have yet to be established. This study aimed to determine its test-retest reliability and smallest detectable change (SDC). A test-retest reliability study. Participants were recruited from the Hypermobility Syndromes Association, a patient organisation in the United Kingdom. Recruitment packs were sent to 1080 adults who had given permission to be contacted about research. BIoH and SF-36 questionnaires were administered at baseline and repeated two weeks later. An 11-point global rating of change scale (-5 to +5) was also administered at two weeks. Test-retest analysis and calculation of the SDC was conducted on 'stable' patients (defined as global rating of change -1 to +1). 462 responses were received. 233 patients reported a 'stable' condition and were included in analysis (95% women; mean (SD) age 44.5 (13.9) years; BIoH score 223.6 (54.0)). The BIoH questionnaire demonstrated excellent test-retest reliability (ICC 0.923, 95% CI 0.900-0.940). The SDC was 42 points (equivalent to 19% of the mean baseline score). The SF-36 physical and mental component scores demonstrated poorer test-retest reliability and larger SDCs (as a proportion of the mean baseline scores). The results provide further evidence of the potential of the BIoH questionnaire to underpin research and clinical practice for people with JHS. Copyright © 2017 Elsevier Ltd. All rights reserved.

The career intentions, work-life balance and retirement plans of dental undergraduates at the University of Bristol.

Science.gov (United States)

Puryer, J; Patel, A

2016-02-26

Aim To investigate the career intentions, work-life balance and retirement plans of dental undergraduates at the University of Bristol in 2015.Method Cross-sectional survey of 210 clinical undergraduates using an anonymous self-report questionnaire.Results The response rate was 79%. The majority (81.7%) were 'satisfied' or 'extremely satisfied' with their choice of career. The majority (78.7%) felt men and women are equally likely to succeed in dentistry, although 42.9% felt men had an advantage over women with regards to career success. The majority (81.6%) intend on working within general practice, 11.3% within hospital dental services and 2.1% within community dental services. The majority (70.5%) intend to specialise within dentistry. Only 1.8% of participants intend on providing only National Health Service (NHS) dental treatment whereas the 86.5% would provide both NHS and private dental treatment. Fifteen years after qualifying, 52.2% plan to work part-time, and 37.8% intend on retiring at the age of 60 or below. The majority (86.6%) felt that childcare should be shared equally between both parents. Female students intend to take more time out of their career to concentrate on childcare and felt that having a child would affect their career more than males.Conclusion The anticipated career plans, work-life balance and retirement plans of undergraduates change over time, and further research should be carried out to monitor future career intentions of dental students in order to help with dental workforce planning.

23rd June 2010 - University of Bristol Head of the Aerospace Engineering Department and Professor of Aerospace Dynamics N. Lieven visiting CERN control centre with Beams Department Head P. Collier, visiting the LHC superconducting magnet test hall with R. Veness and CMS control centre with Collaboration Spokesperson G. Tonelli and CMS User J. Goldstein.

CERN Multimedia

Jean-Claude Gadmer

2010-01-01

23rd June 2010 - University of Bristol Head of the Aerospace Engineering Department and Professor of Aerospace Dynamics N. Lieven visiting CERN control centre with Beams Department Head P. Collier, visiting the LHC superconducting magnet test hall with R. Veness and CMS control centre with Collaboration Spokesperson G. Tonelli and CMS User J. Goldstein.

How collaborative governance can facilitate quality learning for sustainability in cities: A comparative case study of Bristol, Kitakyushu and Tongyeong

Science.gov (United States)

Ofei-Manu, Paul; Didham, Robert J.; Byun, Won Jung; Phillips, Rebecca; Dickella Gamaralalage, Premakumara Jagath; Rees, Sian

2017-09-01

Quality learning for sustainability can have a transformative effect in terms of promoting empowerment, leadership and wise investments in individual and collective lives and regenerating the local economies of cities, making them more inclusive, safe, resilient and sustainable. It can also help cities move towards achieving the United Nations Sustainable Development Goals (SDGs). Effecting the transformation of cities into Learning Cities, however, requires changes in the structure of governance. Drawing on interviews with key informants as well as secondary data, this article examines how collaborative governance has facilitated quality learning for sustainability in Bristol (United Kingdom), Kitakyushu (Japan) and Tongyeong (Republic of Korea). Focusing on a conceptual framework and practical application of learning initiatives, this comparative study reveals how these cities' governance mechanisms and institutional structures supported initiatives premised on cooperative learning relationships. While recognising differences in the scope and depth of the learning initiatives and the need for further improvements, the authors found evidence of general support for the governance structures and mechanisms for learning in these cities. The authors conclude by recommending that (1) to implement the Learning Cities concept based on UNESCO's Key Features of Learning Cities, recognition should be given to existing sustainability-related learning initiatives in cities; (2) collaborative governance of the Learning Cities concept at both local and international levels should be streamlined; and (3) UNESCO's Global Network of Learning Cities could serve as a hub for sharing education/learning resources and experiences for other international city-related programmes as an important contribution to the implementation of the SDGs.

[Bristol Stool Chart: Prospective and monocentric study of "stools introspection" in healthy subjects].

Science.gov (United States)

Amarenco, G

2014-09-01

The Bristol Stool Chart (BSC) allows patients to identify their stool form using seven different images with accompanying written descriptors. Stool form was found to correlate better than stool frequency with whole-gut transit as measured by a radio-opaque marker study. This score is widely used in order to verify the presence of a constipation and to evaluate the therapeutic impact of various treatments. In our clinical practice, we was strongly surprised by the facility and the great precision of the patients to report their stool form, meaning that they usually and daily verify these stools. We wanted to precise the goals of a such attitude. Two questionnaires were proposed to healthy and voluntary subjects. Q1 was supposedly presented in order to verify the sensibility of a French version of BSC in a healthy population. Thus, Q1 precised the difficulties or not to understand pictures and written descriptors, asked about exhaustive analysis by means of BSC of stool form and bowel condition. All subjects with history of ano-rectal disorders or specific treatment for bowel dysfunction were excluded. After Q1 fulfilled, Q2 was proposed to the subjects. Q2 was designed to precise the goals of the patient when he look at his stool and the frequency of such an investigation. Finally a specific question concerning the subject opinion about this behavior in terms of bothersome, shame, or metaphysic interrogation. Eighty-five healthy subjects were recruited (42 female and 43 male). Mean age was 37.2 (sd = 15.7). Mean score of BCS was 2.07 (sd =1.05) (2.07 for female and 1.81 for male, P = 0.22). Number of categories of stool form was only 1 in 40%, 2 categories in 31%, 3 in 19%, 4 in 10%. Presence of a constipation defined by category 1 or 2 was found in 17% (23% in F, 12% in M, P = 0.075). Precision of BSC was noted as excellent in 68%, moderated in 18% and poor in 14%. BSC was considered as easy to use in 75%. Frequency of inspection of feces was systematic for 37%, 1

Social marketing ethics: report prepared for the National Social Marketing Centre

OpenAIRE

Eagle, L.; National Social Marketing Centre

2009-01-01

This report has been developed by Professor Lynn Eagle from the Bristol Social Marketing Centre, Bristol Business School University of West of England with contributions from\\ud staff at the National Social Marketing Centre.

Risk factors for road traffic accidents in cats up to age 12 months that were registered between 2010 and 2013 with the UK pet cat cohort ('Bristol Cats').

Science.gov (United States)

Wilson, J L; Gruffydd-Jones, T J; Murray, J K

2017-02-25

Road traffic accidents (RTAs) are a common cause of death and injury in domestic cats, and a concern to many owners. This study assessed potential risk factors for RTAs in cats up to 12 months of age within a UK cat cohort known as 'The Bristol Cats study'. Data were obtained from three questionnaires, completed by cat owners when their cats were approximately 8-16 weeks old, 6 months old and 12 months old. Information was gathered regarding environmental conditions, cat characteristics and owner management factors. Univariable and multivariable logistic regression models were used to assess associations between these factors and RTAs. Of 1264 eligible study cats, 49 (3.9 per cent) had been involved in an RTA, of which 71.4 per cent (35/49) were known to result in fatal injuries. Rural locations were associated with a higher odds of RTAs than towns, cities or suburban locations. An increased odds of an RTA was also associated with cats that were reported by their owners to hunt at the roadside, as well as cats whose owners classified the road by their house as being a 'long straight section of road'. No significant associations were found between coat colour, breed, sex or neuter status and the odds of an RTA. British Veterinary Association.

Honey Do Franchising Group, Inc. Information Sheet

Science.gov (United States)

Honey Do Franchising Group, Inc., a/k/a The Honey Do Service, Inc. (the Company) is located in Bristol, Virginia. The settlement involves renovation activities conducted at properties constructed prior to 1978, located in Bristol, Virginia.

Edasijõudnud valitsuste motiivid / John Pick ; tõlk. Johanna Ross

Index Scriptorium Estoniae

Pick, John

2008-01-01

Kultuuripoliitika kujundamisest arenenenud riikides. Originaali pealkiri: Motives of advanced governments (The arts in a state: A study of government arts policies from ancient greece to the present. Bristol, England: Bristol Classical Press, 1988). Lühidalt autorist lk. 23

Untitled

African Journals Online (AJOL)

children. Sanjay Prabhu is a radiologist, currently on fellowship at Royal. Children's Hospital in Melbourne, Australia. Joanna Kasznia-Brown is a Registrar in Radiology on the Bristol. (UIK) training circuit. Russel Jones is a part-time emergency medicine consultant at. Bristol Children's Hospital and a full-time trapeze artist.

Discover city's master of science posters mark centenary of the physics genius who foretold future

CERN Multimedia

Quinn, J

2002-01-01

The Institute of Physics is marking the centenary of the birth of Paul Dirac, a Bristol physicist, with six Japanese cartoon-style posters. The posters will be on display at Bristol University today - which has been dubbed Dirac Day - to coincide with an afternoon of talks about the physicist (1/2 page).

Book Review: The Political Economy of Work Security and Flexibility. Italy in Comparative Perspective

DEFF Research Database (Denmark)

Leschke, Janine

2013-01-01

Review of F.. Berton, M Richiardi, S. Sacchi: The Political Economy of Work Security and Flexibility: Italy in Comparative Perspective. Policy Press: Bristol, 2012. 190 pp.......Review of F.. Berton, M Richiardi, S. Sacchi: The Political Economy of Work Security and Flexibility: Italy in Comparative Perspective. Policy Press: Bristol, 2012. 190 pp....

INFLUENCE OF DRINKING A PROBIOTIC FERMENTED MILK BEVERAGE CONTAINING BIFIDOBACTERIUM ANIMALIS ON THE SYMPTOMS OF CONSTIPATION

Directory of Open Access Journals (Sweden)

Thaís Rodrigues MOREIRA

2017-05-01

Full Text Available ABSTRACT BACKGROUND Constipation is a chronic problem in many patients all over the world. OBJECTIVE - To evaluate the effect of consumption of a probiotic fermented milk beverage containing Bifidobacterium animalis on the symptoms of constipation. METHODS - This randomized, double-blind controlled trial included 49 female patients aged 20 to 50 years and diagnosed with constipation according to the ROME III criteria (Diagnostic Criteria for Functional Gastrointestinal Disorders and the Bristol Stool Form Scale. The patients were randomized into two groups: the intervention group received the probiotic fermented milk beverage and the control group received non-probiotic milk. Participants were instructed to ingest 150 mL of the beverages during 60 days. At the end of this period, patients were assessed again by the ROME III criteria and Bristol scale. The Wilcoxon test was used to evaluate pre and post-intervention results of the ROME III criteria and Bristol scale. The statistical significance level was considered as 5% ( P ≤0.05. RESULTS - The intervention group showed improvement in the following criteria: straining during a bowel movement ( P <0.001, feeling of incomplete evacuation ( P <0.001 and difficulty in passing stool ( P <0.014, in addition to Bristol scale results ( P <0.001. In the control group, improvements were observed in the following criteria: straining during a bowel movement ( P <0.001, feeling of incomplete evacuation ( P <0.001 and difficulty in passing stool ( P <0.025, in addition to Bristol scale results ( P <0.001. No statistically significant post-intervention differences were observed between the two groups for the Rome III criteria and Bristol scale. CONCLUSION - The results show that the consumption of milk resulted in the improvement of constipation symptoms, regardless of the probiotic culture.

INFLUENCE OF DRINKING A PROBIOTIC FERMENTED MILK BEVERAGE CONTAINING BIFIDOBACTERIUM ANIMALIS ON THE SYMPTOMS OF CONSTIPATION.

Science.gov (United States)

Moreira, Thaís Rodrigues; Leonhardt, Daiane; Conde, Simara Rufatto

2017-01-01

Constipation is a chronic problem in many patients all over the world. - To evaluate the effect of consumption of a probiotic fermented milk beverage containing Bifidobacterium animalis on the symptoms of constipation. - This randomized, double-blind controlled trial included 49 female patients aged 20 to 50 years and diagnosed with constipation according to the ROME III criteria (Diagnostic Criteria for Functional Gastrointestinal Disorders) and the Bristol Stool Form Scale. The patients were randomized into two groups: the intervention group received the probiotic fermented milk beverage and the control group received non-probiotic milk. Participants were instructed to ingest 150 mL of the beverages during 60 days. At the end of this period, patients were assessed again by the ROME III criteria and Bristol scale. The Wilcoxon test was used to evaluate pre and post-intervention results of the ROME III criteria and Bristol scale. The statistical significance level was considered as 5% ( P ≤0.05). - The intervention group showed improvement in the following criteria: straining during a bowel movement ( P <0.001), feeling of incomplete evacuation ( P <0.001) and difficulty in passing stool ( P <0.014), in addition to Bristol scale results ( P <0.001). In the control group, improvements were observed in the following criteria: straining during a bowel movement ( P <0.001), feeling of incomplete evacuation ( P <0.001) and difficulty in passing stool ( P <0.025), in addition to Bristol scale results ( P <0.001). No statistically significant post-intervention differences were observed between the two groups for the Rome III criteria and Bristol scale. - The results show that the consumption of milk resulted in the improvement of constipation symptoms, regardless of the probiotic culture.

Use of the femoral vein ('groin injecting' by a sample of needle exchange clients in Bristol, UK

Directory of Open Access Journals (Sweden)

Maliphant John

2005-04-01

Full Text Available Abstract Background Use of the femoral vein for intravenous access by injecting drug users (IDUs (commonly called 'groin injecting' is a practice that is often observed but on which little is written in the literature. The purpose of this study was to describe self-reported data from a sample of groin injectors on the natural history and rationale regarding their groin injecting, to inform future research and the development of appropriate harm reduction strategies. Methods A convenience sample of groin injectors willing to participate in a semi-structured interview were recruited through the Bristol Drugs Project Harm Reduction Service. The interviews were conducted over the period of one week. Data on transition to groin injecting, rationale for use and incidence of problems were collected. Results Forty seven IDUs currently injecting in their femoral vein ('groin' were interviewed, 66% (n = 31 male and 34% (n = 16 female. Their mean age was 31 yrs (range 17 to 50 yrs; SD = 7.7. The mean length of time since first injecting episode was 9.6 yrs (range 6 mths to 30 yrs; SD = 7.0. The mean length of time since use of the groin began was 2.6 years (range 1 mth to 15 yrs; SD = 3.3. The mean length of time between first injection and first use of the groin was 7.0 yrs (SD = 7.0. One person had used no other area for venous access prior to using the groin, nine people had used one, nine people had used two, 10 people had used three, five people had used four and 13 people had used more than four areas. The main reason given for starting to inject in the groin was that 'no other sites were left'. However further discussion identified this meant no other convenient sites were accessible. Practises such as the rotation of injecting sites, as advocated in many harm reduction leaflets, were reported to be difficult and unreliable. The risk of missing the vein and subsequently losing the 'hit' was considered high. Use of the non-dominant hand to administer

Workshop on the Destruction of Bacterial Spores Held in Brussels, Belgium on May 1-3, 1985.

Science.gov (United States)

1985-05-03

Food Research - Bristol Laboratory Langford 4 Bristol BS18 7DY Prof. Grahame Gould, Dr. Derrick Kilsby Unilever Research Laboratory Colworth House...Introduction: Spores & military G. Silverman rations (US Army Labs, Natick, USA) 2. Introduction: Broad review of heat G.W. Gould ( Unilever Research...Cambridge Univ. UK) , and unique chemistry 5. Bacterial spores: chemical/ G.W. Gould ( Unilever Research, biochemical basis of heat resistance Colworth

Practice of Job Seeker Training Conducted by Polytechnic Center and Polytechnic University

Science.gov (United States)

Hoshino, Minoru; Ikeda, Tomozumi; Shiota, Yasuhito

Job seeker training for six months for 15 members was performed by Polytechnic Center Kanto in Yokohama from January, 2006. The injection mold was completed by having made training and a training subject correspond. And employment of all the members who consist of 90 persons during the 6 periods was completed. Furthermore, job seeker training for ten months for ten members was performed by the Polytechnic University from January, 2010. Then, The difficult injection mold was completed and all the members were employed. This paper discussed job seeker training and an employment result.

The Right to be Dead

DEFF Research Database (Denmark)

Sabra, Jakob Borrits; Troyer, John Eric

2018-01-01

Cemetery explicitly embraces death as the singular human experience that is paradoxically both universal and radically individualised. Such an approach creates opportunities for addressing how the human mortality ‘experience’ was transformed during the twentieth-century by specific kinds of First World......We all know death is in the future. We just want to make the future more visible. That is the central design ethos for the Future Cemetery project in Bristol, England. Based at Arnos Vale Cemetery, the Future Cemetery is a partnership between the Centre for Death and Society at the University....../3 the population of Bristol city), either through burial or cremation. It remains a working cemetery that covers 45 acres near the city centre and in June 2012 the Arnos Vale Cemetery Trust signed a new 125-year lease with the city of Bristol. Since its founding, the Future Cemetery has explicitly explored...

Linkages between Alaskan sockeye salmon abundance, growth at sea, and climate, 1955-2002

Science.gov (United States)

Ruggerone, G.T.; Nielsen, J.L.; Bumgarner, J.

2007-01-01

We tested the hypothesis that increased growth of salmon during early marine life contributed to greater survival and abundance of salmon following the 1976/1977 climate regime shift and that this, in turn, led to density-dependent reductions in growth during late marine stages. Annual measurements of Bristol Bay (Bering Sea) and Chignik (Gulf of Alaska) sockeye salmon scale growth from 1955 to 2002 were used as indices of body growth. During the first and second years at sea, growth of both stocks tended to be higher after the 1976-1977 climate shift, whereas growth during the third year and homeward migration was often below average. Multiple regression models indicated that return per spawner of Bristol Bay sockeye salmon and adult abundance of western and central Alaska sockeye salmon were positively correlated with growth during the first 2 years at sea and negatively correlated with growth during later life stages. After accounting for competition between Bristol Bay sockeye and Asian pink salmon, age-specific adult length of Bristol Bay salmon increased after the 1976-1977 regime shift, then decreased after the 1989 climate shift. Late marine growth and age-specific adult length of Bristol Bay salmon was exceptionally low after 1989, possibly reducing their reproductive potential. These findings support the hypothesis that greater marine growth during the first 2 years at sea contributed to greater salmon survival and abundance, which in turn led to density-dependent growth during later life stages when size-related mortality was likely lower. Our findings provide new evidence supporting the importance of bottom-up control in marine ecosystems and highlight the complex dynamics of species interactions that continually change as salmon grow and mature in the ocean. ?? 2007 Elsevier Ltd. All rights reserved.

The impact of the 'Sea Empress' oil spill on seabass recruitment

International Nuclear Information System (INIS)

Lancaster, J.E.; Pawson, M.G.; Pickett, G.D.; Jennings, S.

1998-01-01

Young-of-the-year (O-group) sea bass (Dicentrarchus labrax L.) were collected during 1996 from 12 inshore sites in the Bristol Channel in order to investigate possible effects of the Sea Empress oil spill on their growth and survival. O-group bass were more abundant on the south side of the Bristol Channel than in South Wales nurseries, and particularly scarce within Milford Haven. Some bass caught in nursery areas on the north Cornish coast had spawned in early March, but only fish spawned after late April appeared in South Wales nurseries, where the first arrival data of bass post-larvae was later than in nursery areas in north Devon and Cornwall. O-group bass grew faster within the latter nurseries than in the north coast of the Bristol Channel, where a much higher proportion of fish failed to reach 60 mm, the critical length for survival through the first winter. There were no significant differences in fish condition or in the weight of their stomach contents between sites. Whilst the Sea Empress oil spill may have contributed to the differences in the survival of early-spawned bass larvae and the abundance of O-group bass in nursery areas on either side of the Bristol Channel, these differences are likely to be less significant than the year to year variation due to natural causes. (author)

Green Capital: Student Capital student-led evaluation

OpenAIRE

Runkle, Q.; Haines, T.; Piper, K.; Leach, S.

2016-01-01

To assess and evaluate the impact of the Green Capital: Student Capital project, the partnership (the University of the West of England, the University of Bristol, the Students’ Union at UWE, and Bristol Students’ Union) worked with NUS to train a team of students from both universities to lead an evaluation process. There were two key aims for the evaluation: \\ud \\ud • To verify the quantitative outputs of the Green Capital: Student Capital project; \\ud • And to make a qualitative assessment...

Efficacy of Polytechnic students’ Interpersonal Communication Skills

Directory of Open Access Journals (Sweden)

Zaharatul Akmar Ahmad Zainuddin

2012-07-01

Full Text Available Every year polytechnics in Malaysia produce thousands of graduates in vocational areas, however, these graduates have to strive in a competitive job market against graduates from other tertiary institutions. This study aims to investigate polytechnic students efficacy on their communication skills. These skills are crucial in determining their chances for employment and would also enable them to perform effectively at workplace. Final semester students from Politeknik Sultan Salahuddin Abdul Aziz Shah (n=120 were asked to assess their own communication skills ability using the Communication Skills self-assessment questionnaire. Findings indicate that polytechnic students are quite confident in their ability to communicate effectively at workplace and job interviews. However, interviews with potential employers indicate differently. Implications of the study include a call for the evaluation of the English proficiency courses currently being implemented in Malaysian polytechnics.

Assessment of financial control practices in Polytechnics in Ghana. A case study of Sunyani Polytechnic

OpenAIRE

Prempeh, Kwadwo Boateng; Twumasi, Patrick; Kyeremeh, Kwadwo

2015-01-01

The study sought to assess the financial Control systems of Polytechnics in Ghana and suggest ways of improving them. Financial control systems exist to help organizations meet their goals and objectives, promote efficiency, reduce the risk of loss, and help ensure financial statement reliability and compliance with laws and regulations. The study adopts the case study design using Sunyani Polytechnic in the Brong Ahafo region, Ghana. A sample size of 50 staff members was selected for the stu...

Efficacy of Polytechnic Students' Interpersonal Communication Skills

Science.gov (United States)

Zainuddin, Zaharatul Akmar Ahmad; Selamat, Suzanah

2012-01-01

Every year polytechnics in Malaysia produce thousands of graduates in vocational areas, however, these graduates have to strive in a competitive job market against graduates from other tertiary institutions. This study aims to investigate polytechnic students efficacy on their communication skills. These skills are crucial in determining their…

Serials Management In Polytechnic Libraries in Nigeria: A ...

African Journals Online (AJOL)

Serials Management In Polytechnic Libraries in Nigeria: A Comparative Study of Kaduna Polytechnic And Yaba College of Technology Libraries. ... Samaru Journal of Information Studies. Journal Home · ABOUT THIS JOURNAL · Advanced ...

Gathering Stones: The Problems of Modern Cultural and Activity Research

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Reed M.,

2017-08-01

Full Text Available Cultural-Historical Psychology 2017. Vol. 13, no. 1, 4–22 doi:10.17759/chp.2017130101 ISSN: 1816-5435 / 2224-8935 (online Gathering Stones: The Problems of Modern Cultural and Activity Research 28 Reed M., Ph.D., Senior Lecturer in Education, University of Bristol, Graduate School of Education, Bristol, Great Britain , Malcolm.Reed@bristol.ac.uk Download PDF-fulltext (306 kbFull Text in Russian (PDF, 306 kbPrintRUIn Russian Abstract This paper explores the verbal image of ‘gathering stones’ in order to appreciate the continuing relevance of Vygotsky to the tradition of inquiry that has been inspired by his example and his work. It considers how our tradition is built on the ancient and critical activity of problematization. The meaning and inner value of tradition is explored in relation to problems we address now and have addressed historically, in particular in relation to the problem of an ascendant version of enculturation. The argument ends with a reflection on the difficulties we still face in addressing educational needs.

Teacher professional development through collaborative curriculum design in. Ghana¿s polytechnics

NARCIS (Netherlands)

Bakah, M.A.B.; Bakah, Marie Afua Baah

2011-01-01

This dissertation entitled Teacher professional development through collaborative curriculum design in Ghana‟s polytechnics is a research conducted among polytechnic teachers in Ghana. Polytechnic development, curricular reform, improving the quality of teaching and teachers‟ knowledge needs

Exploring the challenges faced by polytechnic students

Science.gov (United States)

Matore, Mohd Effendi @ Ewan Mohd; Khairani, Ahmad Zamri

2015-02-01

This study aims to identify other challenges besides those already faced by students, in seven polytechnics in Malaysia as a continuation to the previous research that had identified 52 main challenges faced by students using the Rasch Model. The explorative study focuses on the challenges that are not included in the Mooney Problem Checklist (MPCL). A total of 121 polytechnic students submitted 183 written responses through the open questions provided. Two hundred fifty two students had responded from a students' perspective on the dichotomous questions regarding their view on the challenges faced. The data was analysed qualitatively using the NVivo 8.0. The findings showed that students from Politeknik Seberang Perai (PSP) gave the highest response, which was 56 (30.6%) and Politeknik Metro Kuala Lumpur (PMKL) had the lowest response of 2 (1.09%). Five dominant challenges were identified, which were the English language (32, 17.5%), learning (14, 7.7%), vehicles (13, 7.1%), information technology and communication (ICT) (13, 7.1%), and peers (11, 6.0%). This article, however, focus on three apparent challenges, namely, English language, vehicles, as well as computer and ICT, as the challenges of learning and peers had been analysed in the previous MPCL. The challenge of English language that had been raised was regarding the weakness in commanding the aspects of speech and fluency. The computer and ICT challenge covered the weakness in mastering ICT and computers, as well as computer breakdowns and low-performance computers. The challenge of vehicles emphasized the unavailability of vehicles to attend lectures and go elsewhere, lack of transportation service in the polytechnic and not having a valid driving license. These challenges are very relevant and need to be discussed in an effort to prepare polytechnics in facing the transformational process of polytechnics.

PREFACE: The 16th International Conference on Positron Annihilation (ICPA-16)

Science.gov (United States)

Alam, Ashraf; Coleman, Paul; Dugdale, Stephen; Roussenova, Mina

2013-06-01

The 16th International Conference on Positron Annihilation (ICPA-16) was held at the University of Bristol, United Kingdom during 19-24 August, 2012. This triennial conference is the foremost gathering of the Positron Annihilation Physics community and it was hosted in the UK for the first time since the series of meetings first started back in 1965. The University of Bristol, the Alma Mater of Paul Dirac, is situated at the heart of the city, and it has established a worldwide reputation in research and teaching. Many of the topics which were discussed during ICPA-16 form an integral part of the research themes in the schools of Physics, Chemistry and Engineering of this University. ICPA-16 attracted a diverse audience, both from academic and industrial institutions, with over 200 participants from 29 countries. It continued the long held tradition of showcasing novel research in the field of positron annihilation and a total of 170 papers were presented as talks and posters. The papers reported studies of metallic and semi-conducting solids, polymers and soft matter, porous materials, surfaces and interfaces, as well as advances in experimental, analytical and biomedical applications. The high quality of the presented work, coupled with the enthusiastic exchange of ideas, provided an invaluable forum, especially for younger researchers and postgraduate students. The excellence of student presentations was acknowledged by the award of prizes for the best student posters, which were received by David Billington (University of Bristol, UK), Moussa Sidibe (CEMHTI, France) and Hongxia Xu (Tohoku University, Japan). All papers published in the Conference Proceedings were reviewed by ICPA-16 participants. We are indebted to all reviewers who contributed their time and intellectual resources, allowing the refereeing and editing process to move smoothly toward the compilation of the Proceedings. Our sincere thanks and gratitude go to everyone who contributed to the

Polytechnic Developments. Coombe Lodge Report, Study Conference 74/11.

Science.gov (United States)

Further Education Staff Coll., Blagdon (England).

Papers on new developments in vocational-technical education in Britain include: the polytechnic, its academic board and organizational structure (J.V. Pepper, M. Emerson); the development of polytechnic courses: an analysis of the steps to be taken within the school to begin a new course (J.A. Sandbach); course validation and approval: the…

78 FR 27414 - Massachusetts; Major Disaster and Related Determinations

Science.gov (United States)

2013-05-10

..., Berkshire, Bristol, Dukes, Essex, Franklin, Hampden, Hampshire, Middlesex, Nantucket, Norfolk, Plymouth..., Hampshire, Middlesex, Norfolk, Suffolk, and Worcester Counties for snow assistance under the Public...

COASTAL STUDY, BRISTOL COUNTY,RHODE ISLAND USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Coastal study data as defined in FEMA Guidelines and Specifications, Appendix D: Guidance for Coastal Flooding Analyses and Mapping, submitted as a result of a...

An Exploration on Motivation of Non-English Majors in Polytechnics

Institute of Scientific and Technical Information of China (English)

赵庆伟

2016-01-01

This study, undertaken 100 students majoring in electronics in a polytechnic in TianJin, examines the characteristics of learning motivations in students: intrinsic and extrinsic motivation. Analysis of data acquired from a questionnaire suggests that the majority of polytechnic students are driven by extrinsic motivation.

Translation teaching in Macao’s polytechnic education

Directory of Open Access Journals (Sweden)

Maria de Lurdes Nogueira Escaleira

2013-03-01

Full Text Available This article "Translation teaching in Higher Education in Macau at the Polytechnic" aims to discuss the issues around teaching and learning of Chinese / Portuguese Translation in Macau, and the role played by the Macau Polytechnic Institute in translators training. For more than four centuries, Macau has been a place of intercultural contact where the Portuguese and the Chinese, now the current official languages, have coexisted and implied constant translation efforts; today, Macau is seen as an important platform between the People's Republic of China and Portuguese Speaking Countries, which has stressed the importance of translation professionals. Despite several attempts, Macau’s public higher education was only established in 1991, as well as a translation degree program; until then, and for more than a century, the translators training was held by a government department. We will discuss several curricular structures implemented over the years in the Macao Polytechnic Institute for training translators who can intermediate between Chinese and Portuguese languages and cultures growingly expanding in Macau, given the significant increase in the demand for properly trained translators/interpreters

Profile of mirabegron in the treatment of overactive bladder: place in therapy

Directory of Open Access Journals (Sweden)

Sharaf A

2017-02-01

Full Text Available Ala’a Sharaf, Hashim Hashim Female and Functional Urology Unit, Bristol Urological Institute, Bristol, UK Abstract: Mirabegron is a relatively new drug introduced to treat overactive bladder syndrome. It can be used either on its own or as part of a combination. This drug has been extensively studied, with a good number of Phase II and Phase III trials showing promising outcomes. These studies show that mirabegron is an effective, well-tolerated drug, which could have some adverse effects of concern. In this review, we look at the trials on mirabegron, as well as its pharmacokinetics, mechanism of action, and side effects as documented in the literature. Keywords: mirabegron, overactive bladder disorder, antimuscarinics

Evaluating Self-Efficacy Expected of Polytechnic Engineering Students as a Measure of Employability

Science.gov (United States)

Ojonugwa, Oguche Innocent; Hamzah, Ramlah; Bakar, AB Rahim; Rashid, Abdullah Mat

2015-01-01

In the face of increasing unemployment partly due to decreasing employability skills of Nigeria polytechnic students, many graduates of Nigeria polytechnic have a dwindle self-efficacy. 420 HND 2 polytechnic engineering students in north central states of Nigeria were surveyed. Data were collected using questionnaire consisting of 4 Likert-type…

One-step nucleic acid amplification: the possible value in assessing sentinel lymph node metastasis during mastectomy

Directory of Open Access Journals (Sweden)

Hunter-Smith AE

2018-01-01

Full Text Available Alison E Hunter-Smith, Zenon Rayter Breast Surgery Unit, Bristol Breast Care Centre, North Bristol NHS Trust, Southmead Hospital, Westbury-on-Trym, Bristol, UK Abstract: Breast cancer is the most common cancer in women, worldwide, and 1,400 deaths per day are attributed to it. The success of national screening programs has seen breast cancers being diagnosed at an earlier stage. With conservative surgery to the breast demonstrating equivalent long-term outcomes, the last 10 years have seen a growing interest in the safety of less invasive management for the axilla in breast cancer patients. One-step nucleic acid amplification (OSNA is a validated, reliable, and efficient tool in identifying micro- and macro-metastases intraoperatively. It is the most widely used intraoperative analysis tool within the United Kingdom, and is employed by over 320 units across Europe and Asia. Recent evidence from the AMAROS, IBCSG 23-01, and ACOSOG Z0011 trials has changed surgical practice in managing the axilla of patients with breast cancer. We propose a clinical algorithm demonstrating the role of OSNA as an intraoperative analysis tool in today’s management of breast cancer as well as prospects for the future use of OSNA. Keywords: breast cancer, sentinel lymph node, intraoperative assessment, one-stop nucleic acid amplification, mastectomy

Convection enhanced delivery of panobinostat (LBH589-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model

Directory of Open Access Journals (Sweden)

Singleton WG

2017-02-01

Full Text Available WG Singleton,1,2 AM Collins,3 AS Bienemann,1 CL Killick-Cole,1 HR Haynes,4 DJ Asby,1 CP Butts,5 MJ Wyatt,1 NU Barua,1,2 SS Gill1,2 1Functional Neurosurgery Research Group, School of Clinical Sciences, University of Bristol, 2Department of Neurosurgery, North Bristol NHS Trust, 3Bristol Centre for Functional Nanomaterials, School of Physics, HH Wills Physics Laboratory, 4Brain Tumour Research Group, School of Clinical Sciences, 5School of Chemistry, University of Bristol, Bristol, UKBackground: The pan-histone deacetylase inhibitor panobinostat is a potential therapy for malignant glioma, but it is water insoluble and does not cross the blood–brain barrier when administered systemically. In this article, we describe the in vitro and in vivo efficacy of a novel water-soluble nano-micellar formulation of panobinostat designed for administration by convection enhanced delivery (CED.Materials and methods: The in vitro efficacy of panobinostat-loaded nano-micelles against rat F98, human U87-MG and M059K glioma cells and against patient-derived glioma stem cells was measured using a cell viability assay. Nano-micelle distribution in rat brain was analyzed following acute CED using rhodamine-labeled nano-micelles, and toxicity was assayed using immunofluorescent microscopy and synaptophysin enzyme-linked immunosorbent assay. We compared the survival of the bioluminescent syngenic F98/Fischer344 rat glioblastoma model treated by acute CED of panobinostat-loaded nano-micelles with that of untreated and vehicle-only-treated controls.Results: Nano-micellar panobinostat is cytotoxic to rat and human glioma cells in vitro in a dose-dependent manner following short-time exposure to drug. Fluorescent rhodamine-labelled nano-micelles distribute with a volume of infusion/volume of distribution (Vi/Vd ratio of four and five respectively after administration by CED. Administration was not associated with any toxicity when compared to controls. CED of

Presidential Green Chemistry Challenge: 2004 Greener Synthetic Pathways Award

Science.gov (United States)

Presidential Green Chemistry Challenge 2004 award winner, Bristol-Myers Squibb, manufactures paclitaxel, the active ingredient in the anticancer drug, Taxol, using plant cell fermentation and extraction to replace synthesis.

A Study of Kaduna Polytechnic, Kaduna

African Journals Online (AJOL)

2018-01-30

Jan 30, 2018 ... higher institution in Nigeria, the reasons for its use and related eye ... higher institution, reasons .... management of Kaduna Polytechnic. .... Financial support and sponsorship. Nil. ... Norwalk, CT: Appleton and Lange; 1996. p.

Observations on multiple pion production by hadrons of cosmic radiation

International Nuclear Information System (INIS)

Mantovani, M.S.M.

1971-01-01

Using two emulsion chambers exposed at Mt. Chacaltaya with jet producer layers of pitch, about 100 nuclear interactions were detected and analyzed. The results are compared with other experiments. Emission of a small fireball with M sub(γ) approximately equal to 1.3 Gev/c 2 is confirmed im multiple production process. Re-analysis of the Bristol-Bombay experiment of a balloon emulsion chamber confirmed the existence of such emission and added informations about emission of a intermediate state of higher mass (M sub(γ) approximately equal to 7.7 Gev/c 2 ). Fireball analysis on the Texas Lone Star of the Bristol Group shows a fireball of still larger mass (M sub(γ) approximately equal to 78 Gev/c 2 )

Nocturia Think Tank: focus on nocturnal polyuria: ICI-RS 2011.

Science.gov (United States)

Weiss, Jeffrey P; Bosch, J L H Ruud; Drake, Marcus; Dmochowski, Roger R; Hashim, Hashim; Hijaz, Adonis; Johnson, Theodore M; Juul, Kristian Vinter; Nørgaard, Jens Peter; Norton, Peggy; Robinson, Dudley; Tikkinen, Kari A O; Van Kerrebroeck, Philip E V; Wein, Alan J

2012-03-01

The following is a report of the proceedings of the Nocturia Think Tank sessions of the annual International Consultation on Incontinence-Research Society, which took place June 13-15, 2011 in Bristol, UK. The report is organized into sections pertaining to the main topics of discussions having occurred at that meeting, centering on the relationship of nocturnal polyuria (NP) and nocturia but also synthesizing more current evidence advancing our knowledge of the diagnosis and management of nocturia. This article is not meant to be a comprehensive review on the subject of nocturia, a number of which are available in the recent literature. All authors were physically present during, or in a preliminary session just prior to, the meeting in Bristol. Copyright © 2012 Wiley Periodicals, Inc.

Maailma majandusse suurkontsernide kaudu / Tiina Hakman

Index Scriptorium Estoniae

Hakman, Tiina

1996-01-01

Maailma suurfirmade esindused Eestis: Ericsson, ABB, Coca-Cola, McDonalds, Bristol-Meyers Squibb, Neste, Shell. Ilmunud ka: Molodjozh Estonii, 6. aug. 1996, lk. 3; Russkaja Gazeta, 27. aug. 1996, lk. 3

77 FR 59014 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-09-25

... Exide Technologies Bristol, TN........ 09/10/12 09/07/12 (Company). 81957 Edmund Optics, Inc. Pennsburg...'' (Workers). 81962 Verizon Business Richardson, TX..... 09/11/12 09/10/12 (Workers). 81963 Eco Energy...

AFSC/RACE/MACE: Results of 2014 Pollock Acoustic-Trawl Survey Bering Sea- DY1407

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Eastern Bering Sea shelf walleye pollock (Gadus chalcogrammus) midwater abundance and distribution were assessed from Bristol Bay in the United States, to Cape...

characterisation of silica surfaces iii: characterisation of aerosil

African Journals Online (AJOL)

Preferred Customer

Department of Chemistry, University of Botswana, Private Bag 00704, Gaborone, Botswana ... engineering, chemical and drug delivery, chemical and biochemical diagnostics, nano ..... Morgan, J.C. Ph.D. Thesis, University of Bristol, UK, 1976.

PHOTOSYNTHESIS

Energy Technology Data Exchange (ETDEWEB)

Bryant, Donald A. [Pennsylvania State Univ., University Park, PA (United States)

2002-06-21

The Gordon Research Conference (GRC) on PHOTOSYNTHESIS was held at Roger Williams University, Bristol, RI. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

AFSC/RACE/MACE: Results of 2012 Pollock Acoustic-Trawl Survey Bering Sea- DY1207

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Eastern Bering Sea shelf walleye pollock (Theragra chalcogramma) midwater abundance and distribution were assessed from Bristol Bay in the United States, to Cape...

77 FR 17458 - Marine Mammals; File No. 17159

Science.gov (United States)

2012-03-26

... Simon Nash, Parthenon Entertainment Ltd, 34 Whiteladies Road, Bristol, BS8 2LG, United Kingdom, has... Animal Planet in the U.S. and elsewhere internationally. The initial filming period is scheduled for two...

Updating polytechnic teachers' knowledge and skills through teacher design teams in Ghana

NARCIS (Netherlands)

Bakah, M.A.B.; Voogt, Joke; Pieters, Julius Marie

2012-01-01

While teachers and administrators in polytechnics in Ghana have categorically expressed the growing need for the former’s knowledge and skills to be updated in the era of polytechnic transformation, little attention has been paid to the subject. This study reports a professional development

Linus Pauling Memorial Lectures

Science.gov (United States)

Season Ticket is $252 The Moral Arc: How Science Makes Us Morally Better Dr. Michael Shermer Claremont Physics to the New Philosophy Terry Bristol Institute for Science, Engineering and Public Policy 7:00pm

Project Notes

Science.gov (United States)

School Science Review, 1978

1978-01-01

Presents sixteen project notes developed by pupils of Chipping Norton School and Bristol Grammar School, in the United Kingdom. These Projects include eight biology A-level projects and eight Chemistry A-level projects. (HM)

5th August 2008 - British Secretary of State for Innovation, Universities and Skills J. Denham MP with DIUS Director General Designate A. F.M. Smith and PA Catherine Perez meeting British scientists, engineers and technicians.

CERN Multimedia

Maximilien Brice

2008-01-01

Present around the table: Jonathan Ellis\tCERN, Adviser to the Director-General Lyndon R. Evans\tCERN, LHC Project Leader ATLAS Collaboration Catrin Bernius, University College London Dave Charlton, School of Physics and Astronomy, Birmingham CMS Collaboration Robert Bainbridge, Blackett Lab.High Energy Phys.Group, London Peter Sharp, Imperial College, LONDON LHCb Collaboration Themis Bowcock, Department of Physics, Liverpool Malcolm John, Department of Theoretical Physics, Oxford Information Technology James Casey, CERN, Computing engineer Sue Foffano, CERN, Senior Administrator Accelerators Paul Collier, CERN, Senior Physicist David Nisbet, CERN, Electronics Engineer Medical application Manjit Dosanjh, CERN, Senior Engineer Technical students Tom Lansdale, University of the West of England, Bristol Dan Dengate, University of the West of England, Bristol Doctoral student Stephen March, University of Southampton Summer student Hamish Gordon

The pion's pioneers

International Nuclear Information System (INIS)

Anon.

1987-01-01

In 1946, a band of intrepid physicists took a batch of a new kind of photographic emulsion up the Pic du Midi in the French Pyrenees to expose them to cosmic rays. After analysing the results at Bristol, C. M. G. Lattes, H. Muirhead, G. P. S. Occhialini and C. F. Powell were able to announce early the following year that they had seen the long-awaited pi meson, or pion, postulated by Yukawa in 1935 as the carrier of the strong nuclear force. This landmark discovery quickly revitalized particle physics after all its wartime upheavals. At the end of July, the H. H. Wills Physics Laboratory at Bristol was the scene of an unusual and memorable international conference to mark the 40th anniversary of this discovery

The pion's pioneers

Energy Technology Data Exchange (ETDEWEB)

Anon.

1987-10-15

In 1946, a band of intrepid physicists took a batch of a new kind of photographic emulsion up the Pic du Midi in the French Pyrenees to expose them to cosmic rays. After analysing the results at Bristol, C. M. G. Lattes, H. Muirhead, G. P. S. Occhialini and C. F. Powell were able to announce early the following year that they had seen the long-awaited pi meson, or pion, postulated by Yukawa in 1935 as the carrier of the strong nuclear force. This landmark discovery quickly revitalized particle physics after all its wartime upheavals. At the end of July, the H. H. Wills Physics Laboratory at Bristol was the scene of an unusual and memorable international conference to mark the 40th anniversary of this discovery.

Qualitative evaluation of polytechnic school principal’s educational performance

Directory of Open Access Journals (Sweden)

Milanés, Robertoi

2012-07-01

Full Text Available This article describes the shortcomings identified in the educational performance of the polytechnics schools principals, which transcend the process of quality assessment. Its purpose is aimed at providing a system of quality assessment supported by a contextual model for the management process of the polytechnics schools Principals. The novelty of the proposal lies on the logical integrative character of the system of quality of principal’s performance, taking into account the role of Technological and Professional Education and the potential and needs of those principals.

FLOODPLAIN, TOWN OF FAIRHAVEN, BRISTOL COUNTY, MASSACHUSETTS PMR

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

Bristol Bay, Alaska Subarea ESI: INDEX (Index Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains vector polygons representing the boundaries of all the hardcopy cartographic products produced as part of the Environmental Sensitivity Index...

212ʻ Fahrenheiti : eesti luule 2006 / Piret Bristol

Index Scriptorium Estoniae

Bristol, Piret, 1968-

2008-01-01

Järgmistest 2006. a. ilmunud luulekogudest: Ryytle, Indrek. Inglid rokijaamas. Puhja : I. Rüütle ; Runnel, Hando. Viru veri ei värise. Tartu : Ilmamaa ; Vabat, Martin. Mina olengi kirjandusklassik. Tartu : Eesti Kirjanduse Selts ; Korts, Eliina. Lööklaused murravad metsi. Tartu : Eesti Kirjanduse Selts ; Koff, Indrek. Vana laul. Luige : Verb ; Teede, Andra. Takso Tallinna taevas. Luige : Verb ; Vusser, Kaspar. Vusserduste võnked. Tallinn : P. Kukk ; Elbing, Andrus. Siin Beebilõust, tere! : häired pimelinna tänavalt = Ciao, it's Babyface : trouble from the streets of a blind city. Tallinn : Epifanio ; Hint, Miina. Vabaduse vang, ehk, Põrandaalune kirjandus. Tallinn : MR ; Jüriado, Tiiu. Luule on ime. Habaja : Kentaur ; Ligi, Katre. Naabrivalve. Tartu : Ilmamaa ; Krull, Hasso. Talv. Tallinn : Tuum ; Mets, Mae. Pühapäeval on reede. Tartu : Ilmamaa ; Ploom, Ülar. Porr ja sorry. Tallinn : Tuum ; Hirv, Indrek, Surmapõletaja. Tallinn : Tuum ; Piir, Milvi Martina. Kõrkjavaas. Tartu : Fantaasia ; Soomets, Triin. Väljas. Tallinn : Tuum ; Mathura. Kohalolu. Rapla : Allikäärne ; Afanasjev, Vahur. Katedraal Emajões. Tartu ; Brüssel : ID Salong//Sild, Ivar. Spermaga ja puha. Pärnu : Jumalikud Ilmutused ; Meiel, Kaupo. Polügrafisti käsiraamat. Pärnu : Jumalikud Ilmutused ; Kivisildnik, Sven. Vägistatud jäämägi. Pärnu : Jumalikud Ilmutused ; Arder, Ott. Luule sünnib kus sünnib kui sünnib / koost. Leelo Tungal. Tallinn : Tänapäev ; Kompus, Marko. Vallaliste jõgede tõkkejooksja. Tartu : M. Kompus

78 FR 21914 - North Pacific Fishery Management Council (NPFMC); Public Meeting

Science.gov (United States)

2013-04-12

...), Norton Sound Red King Crab (NSRKC), Pribilof Island Golden King Crab (PIGKC), Adak red king crab. Model update and reviews for Snow Crab, Tanner Crab, Saint Matthew Blue King Crab, Bristol Bay Red King Crab...

Taking warfarin (Coumadin, Jantoven) - what to ask your doctor

Science.gov (United States)

... MA: Elsevier; 2016:702-737. Bristol-Myers Squibb Company. Coumadin (warfarin sodium) Information. Updated September 2016. Bmsmedinfo. ... Hurd, MD, Professor of Endocrinology and Health Care Ethics, Xavier University, Cincinnati, OH. Review provided by VeriMed ...

Atomic and Molecular Interactions

International Nuclear Information System (INIS)

2002-01-01

The Gordon Research Conference (GRC) on Atomic and Molecular Interactions was held at Roger Williams University, Bristol, RI. Emphasis was placed on current unpublished research and discussion of the future target areas in this field

Een nieuwe variëteit van Solanum triflorum Nutt

NARCIS (Netherlands)

Ooststroom, van S.J.

1966-01-01

A note on a new variety of Solanum triflorum Nutt., viz. var. dentatum Ooststr., found in 1938 near Nijmegen, prov. Gelderland. SANDWITH (2, p. 346) mentions a plant from Bristol, which is identical with this.

77 FR 26576 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Science.gov (United States)

2012-05-04

...., Manhattan, 12000302 Sedgwick County Wichita Veterans Administration Hospital, (United States Second Generation Veterans Hospitals MPS) 5500 E. Kellogg Ave., Wichita, 12000303 MASSACHUSETTS Bristol County... Administration Hospital Historic District, (United States Second Generation Veterans Hospitals MPS) 79...

Aerial Survey Trend Counts of Harbor Seals in Coastal Alaska (1984-2006) - ADF&G

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Aerial surveys were conducted during 1983–2006 in the Ketchikan, Sitka, Kodiak, and Bristol Bay areas of Alaska to estimate trends in abundance of harbor seals.

Development of Polytechnic Knowledge and Abilities in the Course of Studying Physics

Science.gov (United States)

Imashev, Gizatulla; Abykanova, Bakytgul T.; Rakhmetova, Mairagul T.; Tumysheva, Anar A.; Moldasheva, Raushan N.; Ilyasova, Sandugash S.; Shahimova, Aliya A.

2016-01-01

In this article one of aspects of physics course studying improvement at high schools--the problem of the development of polytechnic knowledge and abilities in modern conditions--is revealed. In this research, the role and place of polytechnic education in the improvement of teaching physics at high schools are revealed, the main pedagogical…

Transition from Polytechnics to Working Life.

Science.gov (United States)

Stenstrom, Marja-Leena

2003-01-01

Surveys of Finnish polytechnic graduates in business/administration (n=896), technology/communications (n=1,021), and health care/social services (n=925) indicated that training prepared them for finding jobs, with variations by field of study. Engineers had the most success in finding permanent, high-status jobs. Dissatisfaction was highest among…

Study on the Strategy of Transforming Students with Learning Difficulties in Polytechnic Schools

Directory of Open Access Journals (Sweden)

Fan Cui

2014-05-01

Full Text Available As demand of China’s social construction increasing and as the development of vocational education, polytechnic school plays an increasing important part, which, on the other hand, constitutes unprecedented challenges to the teaching in polytechnic schools. Most students, in the aspect of vocational education, are those from middle schools who have difficulties in their study. These students are entitled “Underachievers”. They are short in intellectual study and poor in curricular foundations. Teaching tasks cannot be satisfactorily accomplished in many of the polytechnic schools for the increasing number of underachievers. What have been harnessing the polytechnic school development is the poor study effect of these students. In this article, the internal reason of character and the external reason of social influence are analyzed as the cause that contributes to learning difficulties. And this article offers a pragmatic set of ideas for underachiever transformation.

75 FR 24948 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Science.gov (United States)

2010-05-06

... Restaurants, Inc. G CKE Restaurants, Inc. 22-MAR-10 20100429 G Kieppe Patrimonial Ltda. G Sunoco, Inc. G... & Marketing--Tulsa LLC. 20100461 G Nucor Corporation. G NuMit LLC. G NuMit LLC. 20100484 G Bristol-Myers...

Leadership Style Head of Polytechnic Department and Regard with to Work Culture

Science.gov (United States)

Jamaludin, Nur Hasliza Binti; Naim, Nor Azlin Binti; Khamis, Nur Azzarina Binti; Zakaria, Normah Binti

2015-01-01

This study aims to look at the leadership style of the heads of departments in technical education and its relationship to the work culture among lecturers Polytechnic Sultan Abdul Halim Mu'adzam Shah in Jitra, Kedah. This research is very important to the head of polytechnic and lecture to work in the good condition with the good leadership. This…

The funding black hole

CERN Multimedia

2008-01-01

Two physics students at the University of Bristol have organised a petition against the recently-announced funding cut of 80 million by the body that funds physics research in the UK, the Science and Technology Facilities Council (STFC).

Hearts and minds: Agency and discourse on distress.

Science.gov (United States)

Kemp, Martin

2003-01-01

This paper is based on ethnographic fieldwork in south Bristol, United Kingdom, and on the south Atlantic island of St Helena. It addresses the relationship between the experience of psychosocial distress, the language used to express such distress and the socio-cultural constraints on both language and experience. Accounts of emotional distress were obtained from interviews with 36 informants in south Bristol and with 40 informants on St Helena. Informants in both settings shared a Euro-American discourse on the self in which emotional distress is conceived as a breakdown in human agency. This discourse is linked to narrative as a way of depicting and re-affirming individual agency. A prototypical concept of narrative is used in this paper to interpret accounts of emotional distress. This interpretation demonstrates the usefulness of the idea of narrative for understanding such experiences.

Analysis of Criteria for Admission to the Polytechnic “Nikola Tesla” in Gospić

Directory of Open Access Journals (Sweden)

Kristina Devčić

2013-07-01

Full Text Available Much like in the rest of the world, higher education institutions in the Republic of Croatia are working in a turbulent environment. Croatian polytechnics must recognize and understand the changes in their environment in order to be able to properly respond to them. The Polytechnic “Nikola Tesla” in Gospić is one of the polytechnics facing a growing competition, but also the problem of decreasing enrolment. To solve these problems, it is necessary to apply marketing methods and techniques for understanding the process of deciding on applying for admission to the Polytechnic. In order to better understand this process and how it can be influenced, the authors examined the criteria that students use when making this decision. It was established during the research that some of the criteria had a greater impact on the decision to apply for admission (the location of the Polytechnic, professional orientation, reasonable admission requirements and applicability of professional knowledge in practice and employment prospects as the key decision factor, while others had a much smaller impact. In addition, the research has shown that there is no significant difference between male and female respondents with regard to the importance they attach to different criteria. Using factor analysis, the criteria for admission to the Polytechnic were grouped as follows: the quality of education, studying conditions, image of the institution, the cost of education, and the influence of friends and family.

Cities lead on climate change

Science.gov (United States)

Pancost, Richard D.

2016-04-01

The need to mitigate climate change opens up a key role for cities. Bristol's year as a Green Capital led to great strides forward, but it also revealed that a creative and determined partnership across cultural divides will be necessary.

Web 2.0 in Dutch Higher Education

NARCIS (Netherlands)

Westera, Wim

2009-01-01

Westera, W. (2008). Web 2.0 in Dutch Higher Education. In J. Armstrong & T. Franklin (Eds.), A Review of Current and Developing International Practice in the Use of Social Networking (Web 2.0) in Higher Education (pp. 61-71). Bristol: Clex.

Physicist challenges prevailing view of math

CERN Multimedia

Burton, H

2004-01-01

Article about Michael Berry, a renowned mathematical physicist from the University of Bristol in England. Rather than trying to discover profound mathematical relationships in the physical world, Prof. Berry looks to the real world for "applications" of mathematical relationships (1 page)

Crossing the Binary Line: The Founding of the Polytechnic in Colonial Hong Kong

Science.gov (United States)

Wong, Ting-Hong

2014-01-01

Using the case of the Hong Kong Polytechnic (HKP), this paper examines academic drift in colonial settings. The HKP, like polytechnics in the UK, was supposedly a service sector institution. Under the binary system in the UK, schools in the service division were governed by the state educational bureaucracy, while the universities--the autonomous…

The Polytechnic Breakthrough in Denmark 1780-1930

DEFF Research Database (Denmark)

Wagner, Michael

2006-01-01

to the beginning of the 19th century. The analysis is focused on the political construction of the Danish polytechnic Institute and the development in engineering discourse in the period 1830-1930. The ideological changes in the discourse are considered an political effect of the second Industrial Revolution...

Modeling the economic outcomes of immuno-oncology drugs: alternative model frameworks to capture clinical outcomes

Directory of Open Access Journals (Sweden)

Gibson EJ

2018-03-01

Full Text Available EJ Gibson,1 N Begum,1 I Koblbauer,1 G Dranitsaris,2 D Liew,3 P McEwan,4 AA Tahami Monfared,5,6 Y Yuan,7 A Juarez-Garcia,7 D Tyas,8 M Lees9 1Wickenstones Ltd, Didcot, UK; 2Augmentium Pharma Consulting Inc, Toronto, ON, Canada; 3Department of Epidemiology and Preventive Medicine, Alfred Hospital, Monash University, Melbourne, VIC, Australia; 4Health Economics and Outcomes Research Ltd, Cardiff, UK; 5Bristol-Myers Squibb Canada, Saint-Laurent, QC Canada; 6Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada; 7Bristol-Myers Squibb, Princeton, NJ, USA; 8Bristol-Myers Squibb, Uxbridge, UK; 9Bristol-Myers Squibb, Rueil-Malmaison, France Background: Economic models in oncology are commonly based on the three-state partitioned survival model (PSM distinguishing between progression-free and progressive states. However, the heterogeneity of responses observed in immuno-oncology (I-O suggests that new approaches may be appropriate to reflect disease dynamics meaningfully. Materials and methods: This study explored the impact of incorporating immune-specific health states into economic models of I-O therapy. Two variants of the PSM and a Markov model were populated with data from one clinical trial in metastatic melanoma patients. Short-term modeled outcomes were benchmarked to the clinical trial data and a lifetime model horizon provided estimates of life years and quality adjusted life years (QALYs. Results: The PSM-based models produced short-term outcomes closely matching the trial outcomes. Adding health states generated increased QALYs while providing a more granular representation of outcomes for decision making. The Markov model gave the greatest level of detail on outcomes but gave short-term results which diverged from those of the trial (overstating year 1 progression-free survival by around 60%. Conclusion: Increased sophistication in the representation of disease dynamics in economic models

Ocular surface squamous neoplasia in HIV-positive and HIV-negative patients and response to 5-fluorouracil in Angola

Directory of Open Access Journals (Sweden)

Nutt RJ

2014-12-01

Full Text Available Robert J Nutt,1 John L Clements,2 William H Dean3 1Faculty of Medicine and Dentistry, University of Bristol, Bristol, UK; 2Boa Vista Eye Clinic, Benguela, Angola; 3Bristol Eye Hospital, Bristol, UK Background: Ocular surface squamous neoplasia (OSSN is becoming increasingly prevalent and aggressive in Sub-Saharan Africa. It is a phenomenon linked with human immunodeficiency virus (HIV infection, although association rates in Angola are currently unknown. A topical treatment that is effective in HIV-positive and HIV-negative individuals may be preferable to surgery in some contexts. We aimed to estimate the proportion of OSSN associated with HIV in Angola and to report on the success of topical 5-fluorouracil as a primary treatment in HIV-positive and HIV-negative patients.Methods: Photographs of OSSNs taken at presentation and following treatment with 5-fluorouracil in patients presenting to Boa Vista Eye Clinic, Angola, between October 2011 and July 2013 were grouped into HIV-positive and HIV-negative groups and analyzed to compare presenting features and treatment response. Eighty-one OSSNs were analyzed for clinical features and 24 met the inclusion criteria for analysis of treatment response.Results: Eighty-two patients presented with OSSN between October 2011 and July 2013. Twenty-one (26% were HIV-positive and typically had OSSNs that exhibited more pathological features than those in HIV-negative patients. Twenty-four (29% patients met the inclusion criteria for analysis of treatment response; of these, 26 (91% OSSNs in both groups displayed at least partial resolution after one treatment course. In the HIV-positive group, five of eight patients displayed complete resolution, two showed partial resolution, and one failed. In the HIV-negative group, five of 16 showed complete resolution, ten of 16 had partial resolution, and one failed.Conclusion: Individuals presenting with OSSN in Angola are more likely to have HIV infection compared

Electroweak phase transition and some related phenomena – a brief ...

Indian Academy of Sciences (India)

2016-08-24

Aug 24, 2016 ... type EWPT [10] and its impact on the expansion of the Universe [11]. .... tion between this dynamics and the cubic Higgs self- coupling. ..... [12] D Bailin and A Love, Introduction to gauge field theory. (Adam and Hilger, Bristol ...

Correction: Kikuchi, K., et al., Potential of the Angiotensin Receptor Blockers (ARBs Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke. Int. J. Mol. Sci. 2013, 14, 18899–18924.

Directory of Open Access Journals (Sweden)

Kiyoshi Kikuchi

2014-03-01

Full Text Available The original version of the paper [1] reports that “This ACTIVE I study was supported by Pfizer” (Page 18905. However, the sponsors of the ACTIVE I study were actually Bristol-Myers Squibb and Sanofi-Aventis rather than Pfizer.

Garden hazards: trampoline injuries.

Science.gov (United States)

Paul, Siba Prosad; Barnden, Joanna; Kane, Meridith

2016-09-22

Trampolining is more popular than ever, but it can also cause injuries, some of them very serious. Siba Prosad Paul, Torbay Hospital, Torquay, Joanna Barnden, University of Bristol, and Meridith Kane, Yeovil District Hospital, discuss what can be done to prevent them.

75 FR 55810 - Massachusetts; Emergency and Related Determinations

Science.gov (United States)

2010-09-14

... Massachusetts resulting from Hurricane Earl beginning on September 1, 2010, and continuing, are of sufficient... affected by this declared emergency: Barnstable, Bristol, Dukes, Essex, Middlesex, Nantucket, Norfolk... Unemployment Assistance (DUA); 97.046, Fire Management Assistance Grant; 97.048, Disaster Housing Assistance to...

Supercomputers to transform Science

CERN Multimedia

2006-01-01

"New insights into the structure of space and time, climate modeling, and the design of novel drugs, are but a few of the many research areas that will be transforned by the installation of three supercomputers at the Unversity of Bristol." (1/2 page)

76 FR 20551 - Changes in Flood Elevation Determinations

Science.gov (United States)

2011-04-13

... Daily Schillerstrom, Chairman, 05-1256P). Herald. DuPage County Board, Jack T. Knuepfer Administration... Chairman, Board of Spectator. Selectmen, Swansea Town Hall Annex, 68 Stevens Road, Swansea, MA 02777...). 8, 2010, The Easton Administrator, Enterprise News. 136 Elm Street, Easton, MA 02356. Bristol Town...

75 FR 45160 - Ingersoll-Rand/Harrow Products, Inc., Formerly Known as Locknetics Including On-Site Leased...

Science.gov (United States)

2010-08-02

... account under the name Harrow Products, Inc. Accordingly, the Department is amending this certification to... Products, Inc., Formerly Known as Locknetics Including On-Site Leased Workers From Monroe Staffing Services, Adecco USA, Inc., and Infinistaff, LLC, Bristol, CT; Amended Certification Regarding Eligibility To Apply...

Communicate To Evaluate: A Scottish Polytechnic Approach.

Science.gov (United States)

McLachlan, J.; Wood, V.

The paper describes a critical peer review developed at Napier Polytechnic (NP) of Edinburgh, Scotland for the evaluation and monitoring of its courses. Illustrations of the system are based on the accounting courses offered by the Department of Accounting and Law. The paper first describes the creation of NP from an amalgamation of two colleges…

Hydrologic Landscape Classification to Estimate Bristol Bay Watershed Hydrology

Science.gov (United States)

The use of hydrologic landscapes has proven to be a useful tool for broad scale assessment and classification of landscapes across the United States. These classification systems help organize larger geographical areas into areas of similar hydrologic characteristics based on cl...

Top astronomers head to the city. Experts to talk on exciting quasar discoveries.

CERN Multimedia

Grant, S

2002-01-01

The UK National Astronomy Meeting - NAM 2002 - is at Bristol University this week. The meeting is one of the most important regular gatherings of astronomers in the UK. Sponsored by the Royal Astronomical Society and PPARC, it should attract about 300 astronomers from the UK and beyond.

Equal Outcomes--Equal Experiences? Mendip Papers.

Science.gov (United States)

Brownlow, Sue, Ed.

This collection of articles, based on the 1993 annual consultations between the Society for Research into Higher Education (SRHE) and The Staff College (Bristol, England), examines the nature of franchising (partnerships) between further education (vocational and continuing education) and higher education institutions in the United Kingdom. The…

Fine-structure energy levels, oscillator strengths and lifetimes of ...

Indian Academy of Sciences (India)

with the experimental results compiled in the NIST Data Base. Many new ... Keywords. Relativistic fine-structure levels; oscillator strengths; lifetimes. ... have calculated oscillator strengths and lifetimes using the Briet–Pauli R-Matrix ..... [2] The Opacity Project Team, The Opacity Project (Institute of Physics Publishing,. Bristol ...

Wingate, Ursula (2015). Academic Literacy and Student Diversity

African Journals Online (AJOL)

Wingate, Ursula (2015). Academic Literacy and Student Diversity: The Case of Inclusive Practice. Bristol: Multilingual Matters. Reviewed by Thengani H. Ngwenya*. Book review. * Prof. Thengani H. Ngwenya is Director of the Centre for Excellence in Learning and Teaching of the. Durban University of Technology, Durban, ...

Comparative Sand and Rain Erosion Studies of Spinel, Aluminum Oxynitride (ALON), Magnesium Fluoride, and Germanate Glass

Science.gov (United States)

1993-08-01

A speed of 206 m/s (406 knots) was chosen for small particles (ព gim) to simulate aircraft cruising conditions. Seven samples (Table 3) were exposed...Infrared Optical Materials and Their Antireflection Coatings, Bristol, Adam Hilger, 1985. 3. S. Musikant . Optical Materials, New York, Marcel Dekker, 1985

Would a new definition and classification of nocturia and nocturnal polyuria improve our management of patients? ICI-RS 2014

NARCIS (Netherlands)

Bosch, J. L H Ruud; Everaert, Karel; Weiss, Jeffrey P.; Hashim, Hashim; Rahnama'I, M. Sajjad; Goessaert, An Sofie; Aizen, Joshua

2016-01-01

The following is a report of the proceedings of the Nocturia Think Tank sessions of the annual International Consultation on Incontinence - Research Society, which took place September 22-24, 2014 in Bristol, UK. The report is organized into sections pertaining to the main topic of discussion

Technologies of polytechnic education in global benchmark higher education institutions

Science.gov (United States)

Kurushina, V. A.; Kurushina, E. V.; Zemenkova, M. Y.

2018-05-01

The Russian polytechnic education is going through the sequence of transformations started with introduction of bachelor and master degrees in the higher education instead of the previous “specialists”. The next stage of reformation in the Russian polytechnic education should imply the growth in quality of teaching and learning experience that is possible to achieve by accumulating the best education practices of the world-class universities using the benchmarking method. This paper gives an overview of some major distinctive features of the foreign benchmark higher education institution and the Russian university of polytechnic profile. The parameters that allowed the authors to select the foreign institution for comparison include the scope of educational profile, industrial specialization, connections with the leading regional corporations, size of the city and number of students. When considering the possibilities of using relevant higher education practices of the world level, the authors emphasize the importance of formation of a new mentality of an engineer, the role of computer technologies in engineering education, the provision of licensed software for the educational process which exceeds the level of a regional Russian university, and successful staff technologies (e.g., inviting “guest” lecturers or having 2-3 lecturers per course).

Conjunctival-corneal melt in association with carotid artery stenosis

Directory of Open Access Journals (Sweden)

Rosalind MK Stewart

2008-10-01

Full Text Available Rosalind MK Stewart1, Say Aun Quah1, Dan Q Nguyen2, Stephen B Kaye11Royal Liverpool University Hospital, Liverpool, UK; 2Bristol Eye Hospital, Bristol, UKPurpose: To report a case of severe conjunctival-corneal melt in association with carotid artery stenosis.Methods: Observational case report.Results: A 76-year-old man with a history of bilateral severe carotid artery occlusion and nonarteritic ischemic optic neuropathy developed a spontaneous bulbar conjunctival defect. Despite intensive lubrication, and attempts at surgical closure including an amniotic membrane patch graft, it progressed with subsequent adjacent corneal perforation. Thorough investigations revealed no underlying disease, except markedly delayed episcleral vessel filling on anterior segment fluorescein angiography.Conclusions: Neovascularisation is a known factor in the inhibition of ulceration. In light of the findings in this report, ocular ischemia should be considered as a cause or contributing factor in the differential diagnosis of conjunctival-corneal melt.Keywords: conjunctival melt, corneal melt, ocular ischemia, carotid artery stenosis

Treatment of pediatric pulmonary hypertension

Directory of Open Access Journals (Sweden)

Amy Hawkins

2009-06-01

Full Text Available Amy Hawkins, Robert TullohDepartment of Congenital Heart Disease, Bristol Royal Hospital for Children, Bristol UKAbstract: Pulmonary hypertension was once thought to be a rare condition and only managed in specialized centers. Now however, with the advent of echocardiography, it is found in many clinical scenarios, in the neonate with chronic lung disease, in the acute setting in the intensive care unit, in connective tissue disease and in cardiology pre- and postoperatively. We have a better understanding of the pathological process and have a range of medication which is starting to be able to palliate this previously fatal condition. This review describes the areas that are known in this condition and those that are less familiar. The basic physiology behind pulmonary hypertension and pulmonary vascular disease is explained. The histopathologic process and the various diagnostic tools are described and are followed by the current and future therapy at our disposal.Keywords: pulmonary hypertension, congenital heart disease, pulmonary vascular resistance, pulmonary vasodilators

Effective Technological Delivery in Nigerian Polytechnics:Need for Academic Manpower Development Policy

Directory of Open Access Journals (Sweden)

J. K. Adeyemi

2004-06-01

Full Text Available Technical education, especially as provided in the Nigerian polytechnics, leads to the acquisition of practical and applied skills as well as basic scientific knowledge. The production function of the polytechnics in terms of producing quality middle-level manpower through effective teaching delivery depends largely on the quantity and quality of teachers available. However, teacher adequacy is a function of many factors, which include funding, student enrollment overtime, and staff turnover. This article, however, revealed a mismatch between enrollment and available teachers, with huge staff shortfall over the years when the student enrollment was matched with the available teachers, using the ideal teacher-student ratios. Student and teacher projections were carried out based on five-percent annual increase and average teacher-student ratio of 1:12, so as to meet the vision 2010 target year set by the Nigerian government for total development. The projection showed that the polytechnics would require a large additional number of teachers. An all-inclusive funding approach for the polytechnics was recommended so as to increase their financial status, which would allow for improved facilities, workshops, equipment and also improved conditions of service of teachers. We believe that if this was done, more teachers would be attracted from across the world, those who left would return, and new and younger ones will be encouraged to join the teaching force. Such development would to a great extent meet and sustain the anticipated growth for the target year.

Marginal Experiments: Peter Brook and Stepping out Theatre Company

Science.gov (United States)

Harpin, Anna

2010-01-01

This article juxtaposes the recent work of Peter Brook with a Bristol-based mental health service-user collective--Stepping Out Theatre Company. Informed by field-work with the company, this chapter explores the aesthetic and political relationship between professional, experimental theatre work and community-based performance practice. Drawing…

75 FR 52511 - North Pacific Fishery Management Council; Notice of Public Meeting

Science.gov (United States)

2010-08-26

...; review Bristol Bay red king crab CIE report, review and recommend approaches for Tanner crab model, review and recommend approaches for Pribilof Islands blue king crab and red king crab models, receive an...: results of the 2010 survey; snow crab spatial model and management strategy evaluation projects; discuss...

76 FR 50420 - Changes in Flood Elevation Determinations

Science.gov (United States)

2011-08-15

... 20, 2010, Schillerstrom, Chairman, (10-05-1256P). The Daily Herald. DuPage County Board, Jack T..., Easton Administrator, The Enterprise News. 136 Elm Street, Easton, MA 02356. Bristol (FEMA Docket No. B...-0021P). November 22, 2010, Easton Administrator, The Enterprise News. 136 Elm Street, Easton, MA 02356...

77 FR 39265 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-07-02

... Lone Tree, CO....... May 1, 2011 Operation Listing Management and White Pages, Advantage XPO, etc. 81..., Advantage XPO, etc. 81,560B Dex One, National Bristol, TN......... May 1, 2011 Operation Listing Management... directly competitive with articles produced or services supplied by such firm have increased; (B) Imports...

Industrial impact of particle physics

International Nuclear Information System (INIS)

Anon.

1987-01-01

Papers represented at the conference in Bristol devoted to the interrelation of high-energy physics and industry are reviewed in short. Most of speakers confirmed that technologies developd for high-energy physics and mastered with companies are quickly widely adopted industry and other areas of science and technology

[Raamat] / Elisa Loopealne

Index Scriptorium Estoniae

Loopealne, Elisa

2007-01-01

Tutvustus: Bristol, Piret. Nöörist ja seebist. Pärnu : Jumalikud Ilmutused, 2006. (Ji) ; Kivisildnik. Vägistatud jäämägi. Pärnu : Jumalikud Ilmutused, 2006. (Ji) ; Sild, Ivar. Spermaga ja puha. Pärnu : Jumalikud Ilmutused, 2006. (Ji) ; Meiel, Kaupo. Polügrafisti käsiraamat, 2006

Evaluation of Usage of Virtual Microscopy for the Study of Histology in the Medical, Dental, and Veterinary Undergraduate Programs of a UK University

Science.gov (United States)

Gatumu, Margaret K.; MacMillan, Frances M.; Langton, Philip D.; Headley, P. Max; Harris, Judy R.

2014-01-01

This article describes the introduction of a virtual microscope (VM) that has allowed preclinical histology teaching to be fashioned to better suit the needs of approximately 900 undergraduate students per year studying medicine, dentistry, or veterinary science at the University of Bristol, United Kingdom. Features of the VM implementation…

The Influence of Infrastructure Management on Sports Development at State Polytechnics in Bandung

Directory of Open Access Journals (Sweden)

Dede Sujana

2018-03-01

Full Text Available Polytechnic as a higher educational institution trains students to be capable of becoming independent human. It is also responsible for equipping students with competence to compete in the workplace. Sport serves as a means of character and life skills development in students. It is well supported by the infrastructure management in Polytechnic.  Based on the formulation of the problem mentioned above, the general purpose of this study is to determine the effect of infrastructure management on sports development in the State Polytechnic of Bandung. This study employed quantitative approach with survey method to obtain data from questionnaires and physical fitness test. The participants of the study are 77 students from two state polytechnics in Bandung. The result from data processing and analysis showed that 95.7% of sports participation rate is influenced by infrastructure management and the rest of 4.35 is influenced by other unexplainable variables, which means that facility and infrastructure management give positive influence on sports participation.   In addition, other results showed that 93.0% of physical fitness figures are influenced by infrastructure management and 7.0% is influenced by other unexplainable variable, which means that infrastructure gives significant influence on physical fitness. It shows that if sports infrastructure is managed well, then it will greatly influence sports development.

Advancing perspectives of sustainability and large-scale implementation of design teams in Ghana's polytechnics: Issues and opportunities

NARCIS (Netherlands)

Bakah, M.A.B.; Voogt, Joke; Pieters, Julius Marie

2012-01-01

Polytechnic staff perspectives are sought on the sustainability and large-scale implementation of design teams (DT), as a means for collaborative curriculum design and teacher professional development in Ghana's polytechnics, months after implementation. Data indicates that teachers still

Hubble space telescope servicing mission joint ESA/BAE UK technical press briefing Wednesday 10 March 1993

Science.gov (United States)

1993-02-01

On Wednesday 10 March 1993 astronauts from ESA and NASA will be at British Aerospace Space Systems Limited, Filton, Bristol, UK, training on the replacement set of solar arrays which they are scheduled to fit to the Hubble Space Telescope at year end. You are invited to attend a technical briefing on that day, which will be given by senior representatives of the European Space Agency and British Aerospace. The briefing will include details of the design modifications and status of the solar arrays, together with a brief overview of the scientific results already achieved by the teams of astronomers using the telescope. There will be an opportunity for interviews with the mission specialists in the crew of NASA's Space Shuttle flight STS-61, who will be carrying out the servicing mission for the Hubble Space Telescope in a series of "Extra-Vehicular Activities - EVA' (space-walks). Five astronauts are expected : Story Musgrave, Colonel Tom Akers, Jeffrey A. Hoffman, Kathryn C. Thornton from NASA and Claude Nicollier from ESA. There will also be a chance to view the solar arrays in the British Aerospace clean room area where the astronauts are working on their familiarisation programme. The briefing will take place on Wednesday 10 March 1993 at British Aerospace Space Systems, Filton, Bristol, UK (on the northern outskirts of the city of Bristol). The event will begin at 10h30 a.m. and end with a buffet lunch running from approximately 01h30 p.m. to 02h30 p.m. In order to assists with arrangements for travel to and from bristol, British Aerospace proposes to run a free coach from and to London Victoria Coach Station - if there proves to be sufficient press interest. This coach would depart from London at approximately 07h50 a.m. and arrive back at around 05h30 p.m. Further details will be available on request when numbers are known. In order to gain access to the site and the briefing it is essential that all attendees are expected and their names are provided in

Development of the Brussels Infant and Toddler Stool Scale ('BITSS'): protocol of the study

NARCIS (Netherlands)

Vandenplas, Yvan; Szajewska, Hania; Benninga, Marc; Di Lorenzo, Carlo; Dupont, Christophe; Faure, Christophe; Miqdadi, Mohamed; Osatakul, Seksit; Ribes-Konickx, Carmen; Saps, Miguel; Shamir, Raanan; Staiano, Annamaria; Franckx, Johan; Green, Robin; Hegar, Badriul; Lemmens, Roel; Salvatore, Silvia; Vieira, Mario; Verghote, Marc; Xinias, Ioannis

2017-01-01

The Bristol Stool Form Scale (BSS) which consists of 7 photographs of different stool forms allows assessment of stool consistency (scale 1 for hard lumps to scale 7 for watery stools), in an objective manner in adults. The BSS is also sometimes used to characterise the stools of infants and young

Images of the Retailing Environment: An Example of the Use of the Repertory Grid Methodology

Science.gov (United States)

Hudson, Ray

1974-01-01

A necessary condition for studying cognitive images of environments is an appropriate method to define and measure these. Using a sample of students in Bristol, the Repertory Grid method was used to measure images of the retailing environment. The empirical results are discussed and possible future research is outlined. (BT)

The Role of Electronic Reserves in Serving and Shaping New Teaching and Learning Environments in UK Universities.

Science.gov (United States)

Dugdale, Christine

1999-01-01

Describes the ResIDe Electronic Reserve at the University of the West of England (UWE), Bristol, an example of an electronic reserve that has been addressing many access problems and supporting different teaching/learning initiatives. Discusses new roles for the ResIDe electronic library, electronic information management, new librarian roles, and…

A Method of Developing and Introducing Case-Based Learning to a Preclinical Veterinary Curriculum

Science.gov (United States)

Crowther, Emma; Baillie, Sarah

2016-01-01

Case-based learning (CBL) has been introduced as part of a major review of the veterinary curriculum at the University of Bristol. The initial aim was to improve integration between all first year subjects, i.e., basic science disciplines (anatomy, physiology, and biochemistry), animal management, and professional studies, while highlighting the…

Gender Equity Employment in Polytechnics in South East Zone of ...

African Journals Online (AJOL)

Administrator

Uduchukwu (2001) observes that there is gender inequality in ... 2. The Gender Equity Employment Status in State-owned. Polytechnics in South East Zone of Nigeria .... traditional Occupation as well as the Perspectives of Married.

Analysis of the e-learning technologies used for teaching mathematics at Tomsk Polytechnic University

OpenAIRE

Pakhomova, Elena Grigorievna; Yanushchik, Olga Vladimirovna; Dorofeeva, Maria

2016-01-01

This article analyzes the implementation of e-learning technologies in the study of mathematics at Tomsk Polytechnic University. It describes research findings of the suitability of the e-learning technology for first year students of an engineering university. The research involved 248 students and 38 teachers of Tomsk Polytechnic University. The authors surveyed first-year students to check whether they are ready to learn in the electronic environment. In addition, the students and teachers...

77 FR 73986 - Marine Mammals; Issuance of Permits

Science.gov (United States)

2012-12-12

..., Department of Biology, Roger Williams University, Bristol, RI on June 5, 2012, for level B harassment of... INFORMATION for a list of names and address of recipients. ADDRESSES: The Letters of Confirmation and related... research that may result only in taking by level B harassment of marine mammals. The following Letters of...

Eesti kaitsetööstused demonstreerisid oma uusi leiutisi lahinguolukorras / fotod: Meelis Meilbaum

Index Scriptorium Estoniae

2017-01-01

Eesti kaitsetööstusettevõtted korraldasid Tapa keskpolügoonil suurõppusel "Kevadtorm"esitluse, kus näidati uusimate tehnoloogialahenduste toimimist lahingusituatsioonis. Näidislahingus osales Milremi mehitamata maismaasõiduk, Bristol Trust tutvustas ainulaadset õppustel kasutatavat ohutut käsigranaati ning Englo näitas elektrilisi lõhkamismasinaid. Samelin tutvustas uusimaid sõdurijalatseid

Future Time Orientation and Student Expectations: An Empirical Investigation

Science.gov (United States)

Amyx, Douglas; Bristow, Dennis

2004-01-01

Navajo and Anglo college students' time orientation scores from the Future Time Orientation (FTO) Scale (Bristol & Amyx, 1996) were analyzed and compared. Anglo students were found to be significantly more future time oriented in two of the three dimensions: temporal distance and involvement with time. Future time orientation was used to explain…

Why Do Secondary School Chemistry Teachers Engage in Long-Term Outreach Partnership with a University?

Science.gov (United States)

Glover, S. R.; Harrison, T. G.; Shallcross, D. E.

2016-01-01

While the effects of outreach with secondary school pupils has been researched the reasons teachers engage or the impacts on the teachers engaging in long-term relationships with a university department have not. Detailed interviews with chemistry teachers associated with outreach at Bristol ChemLabS have revealed many reasons for prolonged…

Alaskan Salmon and Gen R: Hunting, Fishing to Cultivate Ecological Mindfulness

Science.gov (United States)

Mueller, Michael P.

2015-01-01

Can mining and fisheries co-exist in Bristol Bay, Alaska? To delve into this interesting tension, I expand on Clay Pierce's (this special issue) thoughtful analysis of genetically modified salmon and AquaBounty Technologies, where he explores actor-network theory in relation to scientific literacy and schooling. Further, my essay explores the idea…

78 FR 11187 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Science.gov (United States)

2013-02-15

...; Gores Capital Partners III, L.P. 20130455 G Charlesbank Equity Find VII, Limited Partnership; Francois... Partners II-B, L.P. 01/04/2013 20130479 G The Medicines Company; Bristol-Myers Squibb Company; The... Company. 20130486 G Trident IV, L.P.; GWC Co- Investment Partners, L.P.; Trident IV, L.P. 20130488 G...

Maternal serum fructosamine values after delivery ofmacrosomic ...

African Journals Online (AJOL)

expl.anation for this discrepancy is that the half-lives of these. 1. Brudenell M, Wilds PLo Medical and Surgical Problems in Obstetrics. Bristol: John Wright, 1984: 120-124. 2. Baker JR, O'Connor JP, Metcalf P, Lawson MR, Johnson RN. Oinical usefulness of estimation of serum frucrosamine concentration as a screening.

Expanding the classroom with educational technology: A case study of a Cuban polytechnic high school

Directory of Open Access Journals (Sweden)

Anne Leftwich

2014-12-01

Full Text Available Polytechnic instruction has a common place in the Cuban education system (Gasperini, 2000. In polytechnic institutions, teachers leverage technological tools to prepare students for labor market competences. This case study examined a polytechnic institution in Cuba to consider how teachers defined educational technology. Based on teacher questionnaire responses, site-based teacher interviews, and field observations, technology was primarily viewed as a method for student preparation. In other words, teachers used technology to prepare students for their future careers and the technology they will need to be successful in that career. The study found that teachers highly valued their technical pedagogical training, believed that the growing spaces were an integral part of their technology based instruction, and claimed that the limited resources was their greatest barrier to integrating ICT in the classroom.

Effects of Probiotic Lactobacillus Casei DN-114 001 in Prevention of Radiation-Induced Diarrhea: Results From Multicenter, Randomized, Placebo-Controlled Nutritional Trial

International Nuclear Information System (INIS)

Giralt, Jordi; Regadera, Jose Perez; Verges, Ramona; Romero, Jesus; Fuente, Isabel de la; Biete, Albert; Villoria, Jesus; Cobo, Jose Maria; Guarner, Francisco

2008-01-01

Purpose: To determine whether a probiotic drink containing Lactobacillus casei DN-114 001 reduces the incidence of radiation-induced diarrhea in patients with gynecologic cancer. Methods and Materials: Patients who were undergoing pelvic radiotherapy (45-50 Gy, conventional fractionation) for either cervical carcinoma (radiotherapy and weekly cisplatin) or endometrial adenocarcinoma (postoperative radiotherapy) were randomly assigned to a probiotic drink or placebo, in a double-blind fashion. The probiotic drink consisted of liquid yogurt containing L. casei DN-114 001 at 10 8 CFU/g. The patients recorded the daily the number of bowel movements and scored the stool consistency using the Bristol scale. Diarrhea was graded weekly according the Common Toxicity Criteria system. The primary endpoint was to reduce the incidence of diarrhea, defined by a Common Toxicity Criteria Grade of 2 or greater or the need for loperamide. Results: A total of 85 patients were enrolled. Grade 2 or greater diarrhea and/or the use of loperamide was observed in 24 of 41 patients in the placebo group and 30 of 44 in the probiotic group (p = 0.568). No differences were found in the median time to the presentation of the primary endpoint. Probiotic intervention had a significant effect on stool consistency (p = 0.04). The median time for patients to present with Bristol scale stools of Type 6 or greater was 14 days for patients receiving the probiotic drink vs. 10 days for those receiving placebo. Conclusion: Nutritional intervention with the probiotic drink containing L. casei DN-114 001 does not reduce the incidence of radiation-induced diarrhea as defined by a Common Toxicity Criteria Grade 2 or greater. However, it had a significant effect on stool consistency as measured by the Bristol scale

Animated Simulation: Determining Cost Effective Nurse Staffing for an Acute Care Unit

Science.gov (United States)

1997-06-19

Rate - Unscheduled Physician Visits Post- - Decubitus Ulcer Rate Discharge - Nosocomial Infection Rate (total) - Patient Knowledge of Disease...Condition - Nosocomial Urinary Tract Infection Rate and Care Requirements - Nosocomial Pneumonia Rate - Nosocomial Surgical Wound Infection Rate PROCESS...Nagaprasanna, 1988). A maternity unit at Bristol Hospital displayed dissatisfaction with their patient classification system. They found the patient

A Festival of Contemporary Science for Science Teachers

Science.gov (United States)

Harrison, Tim; Berry, Bryan; Shallcross, Dudley

2010-01-01

In this article, the authors describe the first Festival of Contemporary Science for Science Teachers which was held in January 2010. Focusing on a number of leading-edge science topics, this new festival was organised by Bristol ChemLabS, in collaboration with the Science Learning Centre South West, and involved academics from several departments…

Becoming an Effective Peer Assisted Learning (PAL) Leader

Science.gov (United States)

West, Harry; Jenkins, Rhiannon; Hill, Jennifer

2017-01-01

This Directions paper, written by two former Peer Assisted Learning (PAL) Leaders, (West and Jenkins) and a PAL Tutor (Hill), will support any geographer considering a PAL role. It reflects their experiences of participating in a PAL scheme at the University of the West of England (UWE), Bristol, United Kingdom, and research conducted with…

Testing out the Big bang theory

CERN Multimedia

Rumford, Alex

2007-01-01

"Bristol University academics are among some of the finest minds in the world toiling in a mind-blowingly massive laboratory to find answers to some of the biggest questions that can be asked - about life, the universe and everything. Lucy Parkinson travelled to Switzerland to find out what they are doing there." (2 pages)

Breast cancer

CERN Multimedia

2002-01-01

"Cancer specialists will soon be able to compare mammograms with computerized images of breast cancer from across Europe, in a bid to improve diagnosis and treatment....The new project, known as MammoGrid, brings together computer and medical imaging experts, cancer specialists, radiologists and epidemiologists from Bristol, Oxford, Cambridge, France and Italy" (1 page).

Dansk Almenmedicinsk Forskningsdag - DAF 2013

DEFF Research Database (Denmark)

Jensen, Jacob Reinholdt; Ryborg, Christina Trankjær; Smidth, Margrethe

2013-01-01

Ideen om DAF udsprang på en indisk restaurant for to år siden, da repræsentanter fra det daværende Forskningsudvalg var til Society for Academic Primary Care (SAPC) i Bristol. En konference, hvor den nyeste forskning og de hotteste forskere inden for almen medicin i Storbritannien var repræsenteret...

The GENIUS-test-facility first results on background from $^{222}$Rn daughters

CERN Document Server

Klapdor-Kleingrothaus, H V; Krivosheina, I V; Tomei, C; 10.1016/j.nima.2004.05.033

2004-01-01

GENIUS-TF (Nucl. Instr. and Meth. A 511 (2003) 341; Nucl. Instr. and Meth. A 481 (2002) 149.) is a test-facility for the GENIUS project (GENIUS-Proposal, 20 November 1997; Z. Phys. A 359 (1997) 351; CERN Courier, November 1997, 16; J. Phys. G 24 (1998) 483; Z. Phys. A 359 (1997) 361; in: H.V. Klapdor-Kleingrothaus, H. Pas. (Eds.), First International Conference on Particle Physics Beyond the Standard Model, Castle Ringberg, Germany, 8-14 June 1997, IOP Bristol (1998) 485 and in Int. J. Mod. Phys. A 13 (1998) 3953; in: H.V. Klapdor- Kleingrothaus, LV. Krivosheina (Eds.), Proceedings of the Second International Conference on Particle Physics Beyond the Standard Model BEYOND' 99, Castle Ringberg, Germany 6-12 June 1999, IOP Bristol (2000) 915), a proposed large scale underground observatory for rare events which is based on operation of naked germanium detectors in liquid nitrogen for an extreme background reduction. Operation of naked Ge crystals in liquid nitrogen has been applied routinely already for more th...

Preliminary analysis of force-torque measurements for robot-assisted fracture surgery.

Science.gov (United States)

Georgilas, Ioannis; Dagnino, Giulio; Tarassoli, Payam; Atkins, Roger; Dogramadzi, Sanja

2015-08-01

Our group at Bristol Robotics Laboratory has been working on a new robotic system for fracture surgery that has been previously reported [1]. The robotic system is being developed for distal femur fractures and features a robot that manipulates the small fracture fragments through small percutaneous incisions and a robot that re-aligns the long bones. The robots controller design relies on accurate and bounded force and position parameters for which we require real surgical data. This paper reports preliminary findings of forces and torques applied during bone and soft tissue manipulation in typical orthopaedic surgery procedures. Using customised orthopaedic surgical tools we have collected data from a range of orthopaedic surgical procedures at Bristol Royal Infirmary, UK. Maximum forces and torques encountered during fracture manipulation which involved proximal femur and soft tissue distraction around it and reduction of neck of femur fractures have been recorded and further analysed in conjunction with accompanying image recordings. Using this data we are establishing a set of technical requirements for creating safe and dynamically stable minimally invasive robot-assisted fracture surgery (RAFS) systems.

The 1989 progress report: Polytechnic school laboratories' Direction

International Nuclear Information System (INIS)

1989-01-01

The 1989 progress report of the laboratories' Direction of the Polytechnic School (France) is presented. The research activities carried out in each laboratory are summarized. Scientific and technical cooperation, financial and employement aspects are included. The main fields of research are: biochemistry, chemistry, reaction mechanisms, organic synthesis, mechanics of solids, meteorology, irradiated solids, optics, physics, biophysics, lasers, mathematics, econometrics, epistemology, management and computer science [fr

UAV Survey Data from Clifton Camp (ST56557330, Bristol, UK

Directory of Open Access Journals (Sweden)

Stephen Gray

2015-05-01

Full Text Available This data was collected via low-altitude UAV (Unmanned Aerial Vehicle survey of an area of Clifton Camp (ST565557330, best known for its Iron Age promontory fort. The dataset comprises of metadata records, near-vertical photographs and a derived 3D polygonal mesh. This dataset has been constructed with two kinds of reuse in mind: Firstly, the area surveyed is culturally rich and underexplored; while some of the non-natural features detected by this survey can be identified, others cannot. This data is intended to inform future investigations of the site. Secondly, the survey methodologies employed and the structuring of the resulting dataset are intended to act as an exemplar, a standard method of creating survey data while prioritising open technologies, and of organising UAV survey datasets to ensure maximum re-usability.

Images of Academic Leadership in Large New Zealand Polytechnics

Science.gov (United States)

Cardno, Carol

2013-01-01

As accountability stakes continue to be raised in all education sectors, leadership as a factor that can have an impact on improved student outcomes is being studied with heightened interest. This study was conducted from 2011 to 2012 in New Zealand's large urban polytechnics with the aim of investigating the nature and expectations of academic…

Students' Entrepreneurial Inclination at a Malaysian Polytechnic: A Preliminary Investigation

Science.gov (United States)

Yasin, Ahmad Yasruddin Md; Mahmood, Nik Abdul Aziz Nik; Jaafar, Nik Azyyati Nik

2011-01-01

This paper reports preliminary results of an ongoing project to examine students' inclination towards entrepreneurship at a Malaysian polytechnic. The study used a self-administered questionnaire to explore the influence of entrepreneurial intent, perceived behavioral control, self-efficacy, perceived barriers, perceived support factors and…

Two Sides of the Same Coin: Faculty Doing Research

Science.gov (United States)

Berg, Steven L.

2006-01-01

Dr. Richard Sagor is the Educational Leadership Program Director and a professor in the Department of Education at Lewis & Clark College in Portland, Oregon. Dr. Howard Tinberg is a professor of English at Bristol Community College in Fall River, Massachusetts, where he is also director of the Writing Lab. He is the editor of the journal…

Ground Target Modeling and Validation Conference (10th) Held in Houghton, Michigan, on 17-19 August 1999

Science.gov (United States)

1999-08-01

photoreceptor cells respond to iight,@ Sc. Am., 256 (4): 40-47 (1987). 252 A Model to Evaluate the Decision-Making Process in a Target Acquisition Task Masha ...PO BOX 5 FILTON BRISTOL BS34 7QW UK GILMORE, MARILYN DERA ROOM G007, BUILDING A2 FARNBOROUGH HAMPSHIRE GU14 0LX UK MALTZ, MASHA BEN-GURION

Clopidogrel in infants with systemic-to-pulmonary-artery shunts

DEFF Research Database (Denmark)

Wessel, David L; Berger, Felix; Li, Jennifer S

2013-01-01

BACKGROUND: Infants with cyanotic congenital heart disease palliated with placement of a systemic-to-pulmonary-artery shunt are at risk for shunt thrombosis and death. We investigated whether the addition of clopidogrel to conventional therapy reduces mortality from any cause and morbidity relate......-related morbidity. (Funded by Sanofi-Aventis and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00396877.)....

Towards Improving Students' Attendance and Quality of Undergraduate Tutorials: A Case Study on Law

Science.gov (United States)

Baderin, Mashood A.

2005-01-01

As part of continual efforts towards improving learning and teaching in the faculty, lecturers in the law faculty of the University of the West of England (UWE), Bristol debated the question of students' attendance and quality of tutorials in a recent email discussion amongst themselves. At the end of the debate the need for further research on…

An Analysis of the Changes in Ability and Knowledge of Students Taking A-Level Physics and Mathematics over a 35 Year Period

Science.gov (United States)

Barham, Peter J.

2012-01-01

New undergraduate students arriving to study physics at the University of Bristol from 1975 onwards have all taken the same test of their knowledge and understanding of physics and mathematics. Many of the questions test knowledge of material that has been in the A-level syllabus for maths or physics throughout this period. The ability of incoming…

Greening the Curriculum? History Joins "The Usual Suspects" in Teaching Climate Change

Science.gov (United States)

Hawkey, Kate; James, Jon; Tidmarsh, Celia

2016-01-01

Inspired by the news that Bristol had become the UK's first Green Capital, Kate Hawkey, Jon James and Celia Tidmarsh set out to explore what a "Green Capital" School Curriculum might look like. Hawkey, James and Tidmarsh explain how they created a cross-curricular project to deliver in-school workshops focused on the teaching of climate…

Improving student internship through collaborative curriculum design in Ghanaian polytechnics

NARCIS (Netherlands)

Akomaning, Edward

2012-01-01

The polytechnic institutions in Ghana are required to provide hands-on training with the necessary skills and competencies to students to meet the middle level manpower needs of industry. In order to fulfil this mandate, a student internship programme is an integrated part of the training of

The Constraints of Ghanaian Polytechnics in Adopting Competency Based Training (CBT): The Case of a Pilot-Tested Programme

Science.gov (United States)

Alhassan, Munkaila; Habib, Abdallah Mohammed

2016-01-01

Polytechnics in Ghana view Competency Based Training (CBT) as a major intervention to the perennial constraints confronting its education and training. On the basis of this, and by government policy, a pilot programme of CBT was instituted in all the 10 polytechnics of Ghana, and was pilot tested in, at least, one department. Agricultural…

Democracy and the Portuguese Polytechnic Education. The Case of the Polytechnic Institute of Portalegre (80s of the XX century

Directory of Open Access Journals (Sweden)

Helder Henriques

2015-05-01

Full Text Available In this paper we intend to demonstrate how important was the creation of the Polytechnic Higher Education Institutions as a way to the democratization, access and success in the system of Portuguese higher education in the 70s and 80s of the XX century. Taking the example of the Polytechnic Institute of Portalegre, in particular its School of Education, and using the method of document analysis articulated by content analysis of the interviews with students of the 80s of the XX century, we aimed to highlight the importance of this Higher Education Institution in the democratization on the access and success for a large number of students attending this institution in such a decade. We conclude emphasizing the importance of regional decentralization of higher education institutions across the country and of democratic opportunity in order to allow more citizens to access and complet a degree, regardless of their social, economic and cultural roots. How to reference this article Henriques, H., Marchão, A., & Mourato, J. (2015. A Democracia e o Ensino Superior Politécnico Português. O caso do Instituto Politécnico de Portalegre (década de 80 do séc. XX. Espacio, Tiempo y Educación, 2(2, 173-196. doi: http://dx.doi.org/10.14516/ete.2015.002.002.009

Performance Assesment of Bauchi Polytechnics and Technical Colleges Using Quality Assurance Indicators in Nigeria Qualification Framework

Directory of Open Access Journals (Sweden)

Idris Adamu

2016-07-01

Full Text Available Technical and Vocational Education emphases skill acquisition, Quality Assurance in vocational education is concept that is concerned with high performance involved activities with vocational education such as teaching, learning, infrastructures, student’s behavior and entire academic process. Good quality education is very necessary in the total development of staff and students which ensures proper development, job prospects and the realization of academic goals and objects. Enhanced and sustained to ensure accountability and improve performance. Higher educational institutions in Nigeria continue to experience carelessly attitude about the use of Quality Assurance to understand the risk they are exposed to poor standard. To address these issues, the study embarked upon to determine the level of performance and difference usability of Quality Assurance in Polytechnics and Technical Colleges in Bauchi state. Quantitative method technique was employed using survey questionnaires, 60 staff both senior and junior within these institutions were selected and a questionnaire distributed for their responses. The data were analysed using SPSS software. The result reveals that Federal Polytechnic Bauchi and State Polytechnic Bauchi has high level of Performance about Quality Assurance indicators while College of Education Azare has medium level of Performance. College of education Azare has highest mean rank of 29.87 and percentage of 31.8% obtained from the output result indicated that it has high usability to Quality Assurance, followed by Federal Polytechnic Bauchi with medium usability then State Polytechnic Bauchi has low usability to Quality Assurance. The study concluded by Quality Assurance Unit be made aware to each institution staff to enable recognize the benefits of it. Federal government should give more funding and employ staff to cater the need of Quality Assurance Unit in every institution so that it will help the students to develop

Roles of the polytechnic Ibadan in the academic growth and ...

African Journals Online (AJOL)

Dwindling literacy rate and falling education standard ha ve gained unprecedented attention of the public in the last decade. This paper discuss ed the roles of The Polytechnic Ibadan in the academic growth and development of the nation through bring back book culture and effective utilization of library. The main objective ...

Warfarin Management and Outcomes in Patients with Nonvalvular Atrial Fibrillation Within an Integrated Health Care System.

Science.gov (United States)

An, JaeJin; Niu, Fang; Zheng, Chengyi; Rashid, Nazia; Mendes, Robert A; Dills, Diana; Vo, Lien; Singh, Prianka; Bruno, Amanda; Lang, Daniel T; Le, Paul T; Jazdzewski, Kristin P; Aranda, Gustavus

2017-06-01

times per year), or frequently adjusted warfarin dose (≥ 11 times per year) consistently showed poor TTRs (mean TTR for the highest quartiles was 45.3%-48.3%). A higher TTR was associated with a lower risk of clinical outcomes regardless of frequency of INR monitoring, pharmacist interventions, or number of dose adjustments. Patients whose TTRs were Company and Pfizer. Authors from Bristol-Myers Squibb Company and Pfizer participated in the design of the study, interpretation of the data, review/revision of the manuscript, and approval of the final version of the manuscript. An received a grant for research support from Bristol-Myers Squibb/Pfizer. Niu, Rashid, and Zheng received a grant from Bristol-Myers Squibb/Pfizer to their institutions for salary reimbursement. Vo, Singh, and Aranda are employed by Bristol-Myers Squibb; Bruno was employed by Bristol-Myers Squibb at the time of this study. Mendes and Dills are employed by Pfizer, and Mendes was a member of the Pfizer Cardiovascular and Metabolic Field Medical Team during the time of this study. Lang, Jazdzewski, and Le have no known conflicts of interest to report. Study concept and design were contributed primarily by An and Rashid, along with the other authors. Niu took the lead in data collection, along with Zheng, and data interpretation was performed by An, along with Mendes and Dills, with assistance from the other authors. The manuscript was written by An and revised by Mendes, Dills, Vo, Singh, Bruno, and Aranda, along with Lang, Le, and Jazdezewski. Part of this study's findings was presented at the CHEST 2015 Annual Meeting in Montreal, Canada, on October 28, 2015.

Norovirus Real Time RT-PCR Detection Technology Transition to the Joint Biological Identification and Diagnosis System (JBAIDS)

Science.gov (United States)

2012-09-21

virus and Southampton virus, and II (GII), which includes Bristol virus, Lordsdale virus, Toronto virus, Mexico virus, Hawaii virus and Snow Mountain...Shigella flexneriATCC12022 1 Negative Shigella sonnei ATCC25931 1 Negative Vibrio cholera (NAG) (Culture) 2 Negative Vibrio cholera (Ogawa...Culture) 1 Negative Vibrio cholera (Inaga) (Culture) 1 Negative Sapovivus (Known specimen extract) 2 Negative Rotavirus (Known specimen extract) 2

The End of the Botany Degree in the UK

Science.gov (United States)

Drea, Sinead

2011-01-01

The last student enrolled in a pure "Botany" degree in the UK began in the University of Bristol this year, 2010. In recent years only the University of Reading also offered the Botany degree, before it was dropped there 3 years ago. This short article is written to draw attention to this fact and to a more general relative decline in…

Inventing International Citizenship: Badminton School and the Progressive Tradition between the Wars

Science.gov (United States)

Watkins, Christopher

2007-01-01

This article explores an educational experiment mounted at a public school for girls in Bristol in the 1920s and 1930s. In examining the aims and methods of the Badminton School for girls in this period it aims to do two things. The first is to analyse the relationship between the gendered, class-based and nationalist values of the public school…

Performance Achievement As The Impact Of Strategy Organizatonal Competence Strategy Execution And Competitive Advantage A Study On Private Polytechnics In West Java Indonesia

Directory of Open Access Journals (Sweden)

Bertha Musty

2015-08-01

Full Text Available ABSTRACT - The higher education environment has changed faster than the ability of higher education to respond the competition becomes more intense complex and dynamic making some polytechnics can thrive survive and others are stopping operations. This study was conducted to examine the profile of 29 polytechnics in West Java to achieve organizational performance. Research results show that polytechnic performance is affected by the quality of the execution and its competitive advantage which are determined by the precision and alignment strategies with organizational competence. The model findings of this study could be an analysis tool to solve the polytechnics survival problems how to face the intense competition and changing environment.

Production of strontium-82 for the Cardiogen trademark PET generator: a project of the Department of Energy Virtual Isotope Center

International Nuclear Information System (INIS)

Phillips, D.R.; Peterson, E.J.; Taylor, W.A.; Jamriska, D.J.; Hamilton, V.T.; Kitten, J.J.; Valdez, F.O.; Salazar, L.L.; Pitt, L.R.; Heaton, R.C.; Kolsky, K.L.; Mausner, L.F.; Kurczak, S.; Zhuikov, B.L.; Kokhanyuk, V.M.; Konyakhin, N.A.; Nortier, F.M.; Walt, T.N. van der; Hanekom, J.; Sosnowski, K.M.; Carty, J.S.

2000-01-01

In December of 1989, the United States Food and Drug Administration approved 82 Rb chloride in saline solution for cardiological perfusion imaging by positron emission tomography (PET). The solution is derived from a 82 Sr generator system that is presently manufactured by Bristol Myers Squibb and distributed for clinical application in the United States by Bracco Diagnostics, Inc. Many years of research and development by people in several institutions led up to the approval for clinical use. Currently, there are about 15 sites in the U.S. that perform clinical myocardial perfusion imaging by PET using 82 Rb chloride from the generator. In order to manufacture the generators, Bristol Myers Squibb requires about 1600 mCi of 82 Sr every 30 days. The United States Department of Energy and MDS Nordion, Canada are the current suppliers with qualified Drug Master Files for the production and distribution of this nuclide for the Cardiogen trademark generator. These two entities have worked together over the years to assure the regular, reliable supply of the 82 Sr. Here we describe the facilities and methods used by the Department of Energy in its Virtual Isotope Center to make and distribute the nuclide. (orig.)

Integrated Life Cycle Energy and Greenhouse Gas Analysis of Exterior Wall Systems for Residential Buildings

Directory of Open Access Journals (Sweden)

Reza Broun

2014-11-01

Full Text Available This paper investigates the breakdown of primary energy use and greenhouse gas (GHG emissions of two common types of exterior walls in the U.K.: insulated concrete form (ICF and cavity walls. A comprehensive assessment was conducted to evaluate the environmental performance of each exterior wall system over 50 years of service life in Edinburgh and Bristol. The results indicate that for both wall systems, use phase is the major contributor to the overall environmental impacts, mainly due to associated electricity consumption. For the ICF wall system in Edinburgh, 91% of GHG emissions were attributed to the use phase, with 7.8% in the pre-use and 1.2% in end-of-life phases. For the same system in Bristol, emissions were 89%, 9% and 2%, respectively. A similar trend was observed for cavity wall systems in both locations. It was concluded that in each scenario, the ICF wall system performed better when compared to the cavity wall system. The results of the sensitivity analysis clearly show that the uncertainties relevant to the change of the thickness of the wall are quite tolerable: variable up to 5%, as far as energy and greenhouse emissions are concerned.

Motivation of animal care technicians through recognition.

Science.gov (United States)

Symonowicz, Cammie; Critelli, Linda; Straeter, Pamela

2006-01-01

Keeping employees motivated is a challenge faced by managers in the field of laboratory animal science and in the business world at large. Using Maslow's 'Hierarchy of Needs' theory as a guide, the authors describe how managers can create a recognition program to keep employees feeling happy and rewarded. They discuss programs used at Bristol-Myers Squibb and share lessons learned from various programs.

[Effect of Electroacupuncture at "Neiguan" (PC 6) and "Tianshu" (ST 25) for Colonic Motility and D 2 Receptor in Irritable Bowel Syndrome Rats].

Science.gov (United States)

Wang, Shan; Guo, Meng-Wei; Gao, Yu-Shan; Ren, Xiao-Xuan; Lan, Ying; Ji, Mao-Xian; Wu, Yan-Ying; Li, Kai-Ge; Tan, Li-Hua; Sui, Ming-He

2018-01-25

To observe and compare the effects of electroacupuncture (EA) at "Tianshu" (ST 25) and "Neiguan" (PC 6) for colonic motility and the expression of colon dopamine D 2 in irritable bowel syndrome (IBS) rats, and to explore the specificity of different meridians and different acupoints. Forty Wistar newborn rats were randomly divided into blank, model, Tianshu and Neiguan groups. Separation of mother and child and acetic acid coloclyster combined with colorectal distension were used to establish IBS model in the model, Tianshu and Neiguan groups. At the age of 9 weeks, EA at bilateral ST 25 and PC 6 were applied in the corresponding groups 5 times, once every other day. After the intervention, the Bristol fecal score, the latent period of abdominal retraction reflex and the number of contraction waves were recorded. The expression of dopamine D 2 receptor was detected by immunohistochemistry. Compared with the blank group, the Bristol fecal score of the model group was higher ( P <0.01), the 1 st contraction wave latent period was shorter ( P <0.01), the number of contraction waves in 90 s increased ( P <0.01), the immunoreactive expression of D 2 receptor in colon decreased ( P <0.01). Compared with the model group, the Bristol fecal scores of the Tianshu and Neiguan groups decreased ( P <0.01), the 1 st contraction wave latent periods were longer ( P <0.01), the numbers of contraction waves in 90 s decreased ( P <0.01), the positive expressions of D 2 receptor in colon increased ( P <0.01, P <0.05). Compared with the Tianshu group, the immunoreactive expression of D 2 receptor in the Neiguan group decreased ( P <0.01). EA at ST 25 and PC 6 can improve the symptoms of colonic motility in IBS rats. The effect of EA at ST 25 is better, which indicates that different meridians and different acupoints play specific effects.

H11604: NOS Hydrographic Survey , Bristol Bay, Alaska, 2006-08-20

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

78 FR 42011 - Drawbridge Operation Regulations; The Gut, South Bristol, ME

Science.gov (United States)

2013-07-15

... INFORMATION CONTACT: If you have questions on this rule, call or email Mr. John McDonald, Project Officer, First Coast Guard District, telephone (617) 223-8364, [email protected] . If you have questions...

77 FR 10372 - Drawbridge Operation Regulations; The Gut, South Bristol, ME

Science.gov (United States)

2012-02-22

... INFORMATION CONTACT: If you have questions on this rule, call or email Mr. John W. McDonald, Project Officer, First Coast Guard District, telephone (617) 223-8364. If you have questions on viewing the docket, call...

DIGITAL FLOOD INSURANCE RATE MAP DATABASE, BRISTOL COUNTY, MASSACHUSETTS (ALL JURISDICTIONS)

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

Climate change and potential impacts on bristol bay sockeye salmon populations

Science.gov (United States)

Scientific research has shown that climate change has already caused detectable changes to ecosystems throughout Alaska. As warming is predicted to continue, it is likely to lead to changes in marine and freshwater aquatic ecosystems and impact sockeye salmon populations in Brist...

Viga võib tekitada liigse süükoorma / Piret Bristol

Index Scriptorium Estoniae

Bristol, Piret, 1961-

2006-01-01

Õppivas organisatsioonis ei peaks ruumi olema õpitud abitusel, süüdistamisel ja häbistamisel. Vt. samas: Eksinud ja murest murtud töökaaslasel saab aidata auru välja lasta; Tänitamine tekitab tõrke; Õpitud optimism lubab eksida

Short outlines of books by Estonian authors / Rutt Hinrikus, Janika Kronberg

Index Scriptorium Estoniae

Hinrikus, Rutt, 1946-

2002-01-01

Ehlvest, Jüri. Taevatrepp ; Suuman, Aleksander. Tondihobu tõugud vetikatega ; Õunapuu, Ervin. Mõõk. Nagu jõgi ; Nigov, Anton. Harjutused ; Hainsalu, Lehte. Kellakuuljad ; Heinsaar, Mehis. Härra Pauli kroonikad ; Bristol, Piret. Sajandi öömajad ; Kas kuulete...? : [kuuldemängud] / koost. Tamur Tohver; Rummo, Paul-Eerik. Kohvikumuusikat ; Käsper, Kalle. Vennad Luiged ; Põldroos, Enn. Mees narrimütsiga ; Remsu, Olev. Margit Puusaag ja tema mehed ; Sauter, Peeter. Pori

Automated Control of Endotracheal Tube Cuff Pressure during Simulated Flight

Science.gov (United States)

2016-06-21

accomplished in the intensive care unit (ICU) with stand-alone devices as well as those integral to a ventilator [13,14]. We hypothesized that closed loop ... Administration approved automatic cuff pressure adjustment devices (Intellicuff, Hamilton Medical , Reno, NV; Pyton, ARM Medical , Bristol, CT; Cuff Sentry, Outcome...711th Human Performance Wing U.S. Air Force School of Aerospace Medicine Int’l Expeditionary Educ & Training Dept Air Force Expeditionary Medical

Retention Elasticity and Projection Model for U.S. Navy Medical Corps Officers

Science.gov (United States)

2013-03-01

Department of Defense DODFMR Department of Defense Financial Management Regulation FAP Financial Assistance Program FY Fiscal Year GMO General...deployers who were affected by the increased OPTEMPO. Bristol (2006) finds that increased OPTEMPO has a negative effect on GMO retention. A GMO who was... GMO ) and attrite before completion of obligation service. Furthermore, we do not have information on those who stayed in the Navy in FY2000 and who

Automatic Performance Evaluation for Video Summarization

Science.gov (United States)

2004-07-01

Multimedia 2002, pp.189–198. [14] S. Uchihashi, J. Foote, A. Girgensohn and J. Boreczky, “Video Manga : Generating Seman- tically Meaningful Video...DeMenthon, V. Kobla and D. Doermann, “Video Summarization by Curve Simplification”, ACM Multimedia 98, Bristol, England, pp. 211-218, September 1998. 26 [2...J. Au, “Video Keyframe Production by Efficient Clustering of Compressed Chromaticity Signatures”, ACM Multimedia 2000, Juan-Les-Pins, France, pp. 365

Assessment of Students' Satisfaction of Service Quality in Takoradi Polytechnic: The Students' Perspective

Science.gov (United States)

Anwowie, Samuel; Amoako, Joseph; Abrefa, Amma Adomaa

2015-01-01

Higher educational institutions are increasingly placing greater emphasis on meeting students' expectations and needs as student perceptions of higher educational facilities and services are becoming more important. To investigate students' satisfaction of service quality at the Takoradi Polytechnic, a study was conducted using the SERVQUAL…

An Investigation of the Awareness and Use of Open Access Initiative at the Federal Polytechnic, Offa, Kwara State, Nigeria

Directory of Open Access Journals (Sweden)

Issa, A.O.

2014-09-01

Full Text Available This study investigated the information environment of lecturers in Federal Polytechnic, Offa, Kwara State, Nigeria, in relation to their information seeking behavior, extent of use of the polytechnic library, perceptions of the resources and services of the library, level of awareness and extent of use of the open access model of scholarly communications, as well as the challenges of accessing and using information resources. It adopted the survey research method, using a questionnaire for data collection, while the descriptive statistics method was used to analyse the data, using tabular presentation and simple percentages. From a population of 280 lecturers for the study, a purposive sample of 164 was drawn. The findings showed that the lecturers' information needs are focused on online use; they hardly use the polytechnic library due to their perceptions of the resources and services of the library. They are, to a greater extent, aware of open access initiatives, but do not publish in open access outlets, while various challenges affect their access and use of information resources for teaching and research. A recommendation was made, among others, that the polytechnic management should pay more critical attention to the library especially in the areas of adequate, current and comprehensive collections on all the programmes of the institution, as well as the provision of wireless internet services on the campus through a public-private partnership arrangement.

Long-term functional outcomes of PPPD in children--Nutritional status, pancreatic function, GI function and QOL.

Science.gov (United States)

Park, Hwon-Ham; Kim, Hyun-Young; Jung, Sung-Eun; Lee, Seong-Cheol; Park, Kwi-Won

2016-03-01

The purpose of this study was to analyze the long-term outcomes, such as nutritional status, pancreatic function, gastrointestinal (GI) function, and quality of life (QOL), in children who underwent pylorus-preserving pancreaticoduodenectomy (PPPD). Between 1992 and 2013, there were 15 children who underwent PPPD at Seoul National University Children's Hospital, and 10 of them participated in this study. A retrospective review of the patients' medical records and follow-up was done. Their nutritional statuses were estimated by height, body weight, weight for age Z-score, body mass index (BMI), and serum protein, albumin levels. The endocrine and exocrine functions of the pancreas were estimated by diabetes mellitus (DM), steatorrhea, and Bristol stool chart. The GI function and QOL were evaluated via questionnaires. The follow-up period ranged from 3 to 18years. There were no severe growth disturbances, 6 patients experienced mild steatorrhea and 3 showed above the category 6 in Bristol stool chart. All the patients experienced mild GI symptoms. As for the QOL, there were no significant negative answers, except for one patient with DM. Almost all the study subjects, who underwent PPPD in their childhood, did not present significant problems except for one patient with DM. Copyright © 2016 Elsevier Inc. All rights reserved.

Guidance on future art commissioning.

Science.gov (United States)

2009-05-01

Delegates at Building Better Healthcare's recent "National Patient Environment and the Arts Conference 2009" in London heard how national public arts think tank ixia has appointed Bristol-based arts and wellbeing development agency Willis Newson to write "concise and convincing guidance" on commissioning art for new healthcare facilities. A key message, during a joint presentation, was that integrating artwork into hospitals and other healthcare premises requires the earliest possible consideration to reap the maximum rewards.

Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis

OpenAIRE

Zamli, Zaitunnatakhin; Robson Brown, Kate; Tarlton, John F.; Adams, Mike A.; Torlot, Georgina E.; Cartwright, Charlie; Cook, William A.; Vassilevskaja, Kristiina; Sharif, Mohammed

2014-01-01

Osteoarthritis (OA) is the most common joint disorder characterised by bone remodelling and cartilage degradation and associated with chondrocyte apoptosis. These processes were investigated at 10, 16, 24, and 30 weeks in Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs that develop OA spontaneously. Both strains had a more pronounced chondrocyte apoptosis, cartilage degradation, and subchondral bone changes in the medial than the lateral side of the tibia, and between strains, the ...

Child Behavior and Sibling Relationship Quality: A Cross-Lagged Analysis

OpenAIRE

Pike, Alison; Oliver, Bonamy R.

2016-01-01

Bidirectional associations between sibling relationships and children’s problem behaviors are robust, and links with prosocial behavior have also been reported. Using cross-lagged models, we were able to conservatively test temporal directions of links between positive and negative aspects of sibling relationships and children’s prosocial behavior and conduct problems across a 3-year time span in middle childhood. The Avon Longitudinal Study of Parents and Children (ALSPAC; http://www.bristol...

Spectrum Fatigue of 7075-T651 Aluminum Alloy under Overloading and Underloading

Science.gov (United States)

2016-03-15

Ewalds: Report, Delft University of Technology, Dept. of Metallurgy , Delft, The Nethermands, Oct 1978. 14. P. Bristol, and J. A. Roeleveld: in...Proceedings, European Offshore Steels Research Seminar, The Welding Institute, Abbington Hall, Abbington, Cambridge, U. K., 1980, pp. VI/p. 18-1- VI/p. 18... Welding Institute, Abbington Hall, Abbington, Cambridge, U. K., 1980, pp. VI/p. 15-VI/p. 15-15. 16. J. C. Radon, C. M. Branco, and L. E. Culver

Factors influencing maternal decision-making for the infant sleep environment in families at higher risk of SIDS:a qualitative study

OpenAIRE

Pease, Anna; Ingram, Jenny; Blair, Pete; Fleming, Peter

2017-01-01

Objective: Qualitative interviews with mothers of babies at higher risk of sudden infant death syndrome (SIDS) were carried out to understand their views and decision-making process on the infant sleep environment and safe sleep messages.Design and setting: Twenty semi-structured interviews were conducted between February and November 2014 in deprived areas of Bristol, UK. Mothers were asked about their decision-making for the infant sleep environment and safe sleep messages including infant ...

Interview with Andrew Dalby

OpenAIRE

Mac Con Iomaire, Máirtín

2016-01-01

Andrew Dalby (born 1947 in Liverpool) is an English linguist, translator and historian and author of numerous articles and several books on a wide range of topics including food history, language, and Classical texts. Dalby studied Latin, French and Greek at the Bristol Grammar School and University of Cambridge. Here he also studied Romance languages and linguistics, earning a bachelor's degree in 1970. Dalby worked for fifteen years at Cambridge University Library, eventually specialising i...

Students Life in the Kyiv Polytechnic Institute in the First Years of Its Existence (Late 19th — Early 20th Ct.

Directory of Open Access Journals (Sweden)

O. S. Bilyavska

2016-07-01

Full Text Available The article analyzes the various pages of the life of students of Kyiv Polytechnic Institute in the first years of its existence — educational, scientific, casual and students participated in the revolutionary-democratic movement of Kyiv late 19th—early 20th centuries. Study of student life Kyiv Polytechnic Institute late 19th and early 20th centuries is a separate page in the history of this institution. In conditions of autocracy, strict control of the Government, of the Ministry of Finance, which was subject to institute systematic interference in its activities of the Kyiv authorities and police, students themselves organized and find different ways to influence the improvement of educational and methodical process, improve their daily lives. Analysis of historical sources provides an answer to the causes of the growth of public and revolutionary activity of a large number of students of Kyiv Polytechnic Institute that time. General political crisis of the Russian Empire, autocratic way, national and social oppression, lack of political rights and freedoms have caused strong protests from students. One of the main requirements of students was the recognition of the autonomy of higher education institutions, police interference in their activities. Unfair considered sexual, national and class limit admission to the KPI. Object of study was chosen by the author as Kyiv Polytechnic Institute, its work in the late 19th and early 20th century, as the oldest and reputable higher engineering school at that time. Experience of Kyiv Polytechnic Institute is of great importance for the modern transformation of higher education in Ukraine.

Cross-cultural validation of the educational needs assessment tool into Chinese for use in severe knee osteoarthritis

Directory of Open Access Journals (Sweden)

Zhao H

2018-05-01

Full Text Available Huiwen Zhao,1,* Zhe Dong,2,* Fei Xie,3,4 Guanxin Wang,2 Zhihua Wen,5 Lixia Zhang,5 Mwidimi Ndosi,6,7 Wen Luo1 1Joint Department, The 2nd Ward of Joint Surgery, Tianjin Hospital, Tianjin, China; 2Medical Examination Center, No 6 Hospital, Beijing, China; 3Nursing Experimental Teaching Center, Tianjin Hospital, Tianjin, China; 4College of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin, China; 5Joint Department, The 1st Ward of Joint Surgery, Tianjin Hospital, Tianjin, China; 6Department of Nursing, University of the West of England, Bristol, UK; 7Academic Rheumatology Unit, Bristol Teaching Hospitals, Bristol, UK *These authors contributed equally to this work Background: Patient education is an integral part of the management of osteoarthritis. The educational needs assessment tool (ENAT was developed in the UK to help direct needs-based patient education in rheumatic diseases. Aim: The aim of the study was to adapt and validate the ENAT into Chinese, for use in severe knee osteoarthritis (KOA. Methods: This cross-cultural validation study took two phases: 1 adaptation of the ENAT into Chinese (CENAT and 2 validation of the CENAT. The Construct validity was determined using factor analysis and criterion-related validity by comparing data from CENAT with data from different self-efficacy scales: patient–physician interactions scale (PEPPI-10, self-efficacy for rehabilitation outcome scale (SER, and the self-efficacy for exercise scale (SEE. Results: The sample comprised 196 patients, with mean age 63.6±8.7 years, disease duration was 11.5 years, and 57.1% were female. The CENAT was found to have high internal consistency. The CENAT had weak correlations with the Chinese versions of PEPPI r=0.40, SER r=0.40, and SEE r=0.39. There were no correlations with age r=-0.03 or disease duration r=-0.11. Conclusion: The ENAT translated well into Chinese and has evidence of validity in KOA. Future studies will further inform its

Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 diabetes mellitus

Directory of Open Access Journals (Sweden)

Whaley JM

2012-07-01

Full Text Available Jean M Whaley,1 Mark Tirmenstein,2 Timothy P Reilly,2 Simon M Poucher,3 JoAnne Saye,4 Shamik Parikh,5 James F List61Bristol-Myers Squibb, Metabolic Disease Discovery Biology, Research and Development, Princeton, NJ, USA; 2Bristol-Myers Squibb, Drug Safety Evaluation, Research and Development, New Brunswick and Princeton, NJ, USA; 3AstraZeneca, Cardiovascular and Gastrointestinal Innovative Medicines Science Unit, Alderley Park, Macclesfield, Cheshire, UK; 4AstraZeneca, Global Safety Assessment, Research and Development, Wilmington, DE, USA; 5AstraZeneca, Cardiovascular, Clinical Development, Wilmington, DE, USA; 6Bristol-Myers Squibb, Global Clinical Development, Research and Development, Princeton, NJ, USAAbstract: Sodium-glucose cotransporter-2 (SGLT2 inhibitors are a novel class of glucuretic, antihyperglycemic drugs that target the process of renal glucose reabsorption and induce glucuresis independently of insulin secretion or action. In patients with type 2 diabetes mellitus, SGLT2 inhibitors have been found to consistently reduce measures of hyperglycemia, including hemoglobin A1c, fasting plasma glucose, and postprandial glucose, throughout the continuum of disease. By inducing the renal excretion of glucose and its associated calories, SGLT2 inhibitors reduce weight and have the potential to be disease modifying by addressing the caloric excess that is believed to be one of the root causes of type 2 diabetes mellitus. Additional benefits, including the possibility for combination with insulin-dependent antihyperglycemic drugs, a low potential for hypoglycemia, and the ability to reduce blood pressure, were anticipated from the novel mechanism of action and have been demonstrated in clinical studies. Mechanism-related risks include an increased incidence of urinary tract and genital infections and the possibility of over-diuresis in volume-sensitive patients. Taken together, the results of Phase III clinical studies generally point to a

Using features of a Creole language to reconstruct population history and cultural evolution: tracing the English origins of Sranan.

Science.gov (United States)

Sherriah, André C; Devonish, Hubert; Thomas, Ewart A C; Creanza, Nicole

2018-04-05

Creole languages are formed in conditions where speakers from distinct languages are brought together without a shared first language, typically under the domination of speakers from one of the languages and particularly in the context of the transatlantic slave trade and European colonialism. One such Creole in Suriname, Sranan, developed around the mid-seventeenth century, primarily out of contact between varieties of English from England, spoken by the dominant group, and multiple West African languages. The vast majority of the basic words in Sranan come from the language of the dominant group, English. Here, we compare linguistic features of modern-day Sranan with those of English as spoken in 313 localities across England. By way of testing proposed hypotheses for the origin of English words in Sranan, we find that 80% of the studied features of Sranan can be explained by similarity to regional dialect features at two distinct input locations within England, a cluster of locations near the port of Bristol and another cluster near Essex in eastern England. Our new hypothesis is supported by the geographical distribution of specific regional dialect features, such as post-vocalic rhoticity and word-initial 'h', and by phylogenetic analysis of these features, which shows evidence favouring input from at least two English dialects in the formation of Sranan. In addition to explicating the dialect features most prominent in the linguistic evolution of Sranan, our historical analyses also provide supporting evidence for two distinct hypotheses about the likely geographical origins of the English speakers whose language was an input to Sranan. The emergence as a likely input to Sranan of the speech forms of a cluster near Bristol is consistent with historical records, indicating that most of the indentured servants going to the Americas between 1654 and 1666 were from Bristol and nearby counties, and that of the cluster near Essex is consistent with documents

[Using a multicomponent functional food in IBS patients with constipation a comparative controlled study].

Science.gov (United States)

Pilipenko, V I; Teplyuk, D A; Shakhovskaya, A K; Isakov, V A; Vorobyova, V M; Vorobyova, I S; Sarkisyan, V A; Kochetkova, A A; Mikheeva, G A; Yudina, A V

2016-01-01

Irritable bowel syndrome (IBS) is highly prevalent functional gastrointestinal disorder associated with decrease in quality of life and a high social cost. Diet is one of several therapeutic options in IBS treatment; therefore the development and clinical evaluation of innovative functional food for IBS patients are actual. Instant drink containing 4 g inulin, 4 mg menthol and 2 mg of pyridoxine (in daily dose) has been evaluated. 49 patients 18-68 (41.5±16.5) years old fulfilling the Rome III criteria for IBS-C were randomly assigned into two groups: one received standard diet plus two drinks per day for 2 weeks and control group received standard diet. Response to therapy was recorded daily using Likert scale of abdominal pain, bloating and feeling of incomplete bowel emptying, frequency of bowel movement, Bristol stool scale, and quality of life was assessed by IBSQoL questionnaire before and after the treatment. The consumption of the drink with inulin and menthol contributed to a significant positive effect on the stool parameters (from 0.91±0.73 to 1.12±0.45 bowel movements per day in stool frequency, p=0.05, from 2.68±1.63 to 3.43±1.27 index Bristol scale, p=0.05), reduced the severity of abdominal pain (from 1.78±0.58 to 1.47?0.61 Likert scale points, p=0.05), bloating (from 2.22±0.83 to 1.53±0.71 points ofLikertscale,p= 0.01) and a sense of incomplete bowelemptying (from 2.22 ± 0.88 to 1.61± 0.81 points of Likert scale, p=0.001), as well as increased the quality of life (from 75.3± 12.0 to 83.3±6.7%, p=0.05), but a significant part of patients (10 of 25) complained the appearance of heartburn after the start of the treatment. In conclusion, the consumption of the functional drink containing inulin, menthol and pyridoxine is associated with improve in stool parameters, abdominal pain, Bristol scale index and increase in quality of life in patients with IBS-C, but produce noticeable heartburn. Changes in functional drink composition are needed to

9th Annual Conference of the North East Polytechnics Mathematical Modelling & Computer Simulation Group

CERN Document Server

Bradley, R

1987-01-01

In recent years, mathematical modelling allied to computer simulation has emerged as en effective and invaluable design tool for industry and a discipline in its own right. This has been reflected in the popularity of the growing number of courses and conferences devoted to the area. The North East Polytechnics Mathematical Modelling and Computer Simulation Group has a balanced representation of academics and industrialists and, as a Group, has the objective of promoting a continuing partnership between the Polytechnics in the North East and local industry. Prior to the present conference the Group has organised eight conferences with a variety of themes related to mathematical modelling and computer simulation. The theme chosen for the Polymodel 9 Conference held in Newcastle upon Tyne in May 1986 was Industrial Vibration Modelling, which is particularly approp riate for 'Industry Year' and is an area which continues to present industry and academics with new and challenging problems. The aim of the Conferen...

G minus TWO plus EMILIO

CERN Document Server

Farley, Francis J M

2002-01-01

This verbatim transcription of a talk given on the occasion of Emilio Picasso's retirement from CERN in 1992 describes how he came to the organization following an improbable encounter with the author in a Bristol pub and his contribution to the first muon storage ring. It traces the series of false arguments leading to the discovery of the 'magic energy' used in the second muon storage ring, reviews his leadership style, and includes some physics results.

Airport Activity Statistics of Certificated Route Air Carriers

Science.gov (United States)

1988-12-31

City/Ft.RileyKennewick, WA Pasco/Kennewick/Richand Kilgore, TX Longview/Kilgore/Gladewater Kingsford, MI Iron Mountain /Kingsford Kingsport. TN Bristol...1744.94 4865.07 MON MOUNTAIN /IKINIOF N 0.00(FORD) M- FEDERAL ESS ........................... DOMESTIC ........... S 96.10 96.10 N S - NmmddUd AS -A...C--71 ............ 2 2 212 TOTAL DEPARMUE PERVM COMPL0 EPTE S AlEA STARE ORW " TYPE oF DEPARTURES COMMUNITY CAM OPERATION RAIT 80iNNUDO (AIRORT NAME

Parenting styles, parenting practices, and physical activity in 10- to 11-year olds

OpenAIRE

Jago, Russell; Davison, Kirsten K.; Brockman, Rowan; Page, Angie S.; Thompson, Janice L.; Fox, Kenneth R.

2011-01-01

Objective The objective of this study was to determine whether parenting styles and practices are associated with children's physical activity. Methods Cross-sectional survey of seven hundred ninety-two 10- to 11-year-old UK children in Bristol (UK) in 2008–2009 was conducted. Accelerometer-assessed physical activity and mean minutes of moderate-to-vigorous physical activity (mean MVPA) and mean counts per minute (mean CPM) were obtained. Maternal parenting style and physical activity parenti...

Defense Small Business Innovation Research Program (SBIR). Abstracts of Phase I Awards. 1986.

Science.gov (United States)

1986-01-01

CLINICS TO DETECT HUMAN LEPTOSPIROSIS AND BY VETERINARIANS IN THE FIELD FOR DIAGNOSIS OF THIS DISEASE IN LIVESTOCK. " CRAIG DEVELOPMENT CORP DARPA...50,000 7767 E QUAKER RD ORCHARD PARK, NY 14127 * DWIGHT R CRAIG *TITLE: SMALL HIGH POWER HIGH ENERGY DENSITY BATTERIES T 9 OFFICE: DARPA THE MILITARY...FISCAL YEAR 1986 AWARDED SUBMITTED BY DEPT AMOUNT ] DEEGAN RESEARCH GP INC NAVY $ 49,162," 728 BRISTOL FERRY RD PORTSMOUTH, RI 02871 T DEEGAN TITLE

Evaluation of the cycling city and towns programme: Qualitative research with residents

OpenAIRE

Christensen, J.; Chatterjee, K.; Marsh, S.; Sherwin, H.; Jain, J.

2012-01-01

Between 2008 and 2011, the Department for Transport , Cycling England and the Department of Health invested over £43m (plus local match funding) to create the twelve Cycling City and Towns (CCTs): Greater Bristol, Blackpool, Cambridge, Chester, Colchester, Leighton-Linslade, Shrewsbury, Stoke-on-Trent, Southend, Southport, Woking and York. The aim of the programme was to explore the relationship between investment in cycling, as part of a whole-town strategy, and the number of cyclists and fr...

Insulin glargine in the management of diabetes mellitus: an evidence-based assessment of its clinical efficacy and economic value

OpenAIRE

Clissold, Steve

2007-01-01

Rhian Clissold1, Steve Clissold21Endocrinology Department, Frenchay Hospital, Bristol, UK; 2Content Ed Net Communications S.L., Madrid, SpainIntroduction: Diabetes is a chronic disease associated with high morbidity and mortality, which represents a major public health concern. Interventions that can enhance patient care and reduce clinic visits will not only relieve some of this burden, they will also improve patient QOL and wellbeing.Aims: This review assesses the evidence for the use of in...

Fundamentals and clinical perspective of urethral sphincter instability as a contributing factor in patients with lower urinary tract dysfunction--ICI-RS 2014.

Science.gov (United States)

Kirschner-Hermanns, Ruth; Anding, Ralf; Rosier, Peter; Birder, Lori; Andersson, Karl Erik; Djurhuus, Jens Christian

2016-02-01

Urethral pathophysiology is often neglected in discussions of bladder dysfunction. It has been debated whether "urethral sphincter instability," referred to based on observed "urethral pressure variations," is an important aspect of overactive bladder syndrome (OAB). The purpose of this report is to summarize current urethral pathophysiology evidence and outline directions for future research based on a literature review and discussions during the ICI-RS meeting in Bristol in 2014. Urethral pathophysiology with a focus on urethral pressure variation (UPV) was presented and discussed in a multidisciplinary think tank session at the ICI_R meeting in Bristol 2014. This think tank session was based on collaboration between physicians and basic science researchers. Experimental animal studies or studies performed in clinical series (predominantly symptomatic women) provided insights into UPV, but the findings were inconsistent and incomplete. However, UPV is certainly associated with lower urinary tract symptoms (likely OAB), and thus, future research on this topic is relevant. Future research based on adequately defined clinical (and urodynamic) parameters with precisely defined patient groups might shed better light on the cause of OAB symptoms. Further fundamental investigation of urethral epithelial-neural interactions via the release of mediators should enhance our knowledge and improve the management of patients with OAB. © 2016 The Authors. Neurourology and Urodynamics published by Wiley Periodicals, Inc.

ISAMBARD: an open-source computational environment for biomolecular analysis, modelling and design.

Science.gov (United States)

Wood, Christopher W; Heal, Jack W; Thomson, Andrew R; Bartlett, Gail J; Ibarra, Amaurys Á; Brady, R Leo; Sessions, Richard B; Woolfson, Derek N

2017-10-01

The rational design of biomolecules is becoming a reality. However, further computational tools are needed to facilitate and accelerate this, and to make it accessible to more users. Here we introduce ISAMBARD, a tool for structural analysis, model building and rational design of biomolecules. ISAMBARD is open-source, modular, computationally scalable and intuitive to use. These features allow non-experts to explore biomolecular design in silico. ISAMBARD addresses a standing issue in protein design, namely, how to introduce backbone variability in a controlled manner. This is achieved through the generalization of tools for parametric modelling, describing the overall shape of proteins geometrically, and without input from experimentally determined structures. This will allow backbone conformations for entire folds and assemblies not observed in nature to be generated de novo, that is, to access the 'dark matter of protein-fold space'. We anticipate that ISAMBARD will find broad applications in biomolecular design, biotechnology and synthetic biology. A current stable build can be downloaded from the python package index (https://pypi.python.org/pypi/isambard/) with development builds available on GitHub (https://github.com/woolfson-group/) along with documentation, tutorial material and all the scripts used to generate the data described in this paper. d.n.woolfson@bristol.ac.uk or chris.wood@bristol.ac.uk. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

People

Science.gov (United States)

2001-01-01

Thrilled at @Bristol Kathy Sykes in conversation with Liz Whitelegg. Kathy Sykes is Senior Science Consultant at @Bristol - a new area on Bristol's Harbourside with a Science Centre Explore, a Wildlife Centre Wildscreen, with sculptures and fountains. Kathy was one of five people in 1999 to be awarded an IOP Public Awareness of Physics award. Dr Kathy Sykes What attracted you to Physics in the first place? It was really when I discovered that Physics was all about making models of the world, because then suddenly the ability to be creative became important. I liked the idea that you could have a picture of the world that might work quite well but you could always replace that with a better one. That was what made science come alive and make it seem like something that I'd really love to be involved in, rather than science as a stale body of facts that I needed to learn. I was much more interested in ideas than in facts. I think that finding out about 'models' happened around the time I was discovering quantum mechanics and how the act of observing something can actually affect the outcome. I found it incredibly exciting - especially how that changed the whole philosophy of science. I also had a fantastic teacher in physics and I owe an awful lot to him. He just swooped in at the last moment when I was considering giving it up so that made an enormous difference. After my degree I went to teach maths and physics A-level in Zimbabwe with the VSO, and it was partly wanting to share my excitement with other people about physics that made me want to go and teach abroad. When I came back and began my PhD in Physics at Bristol University, I missed teaching and thought it was important to get the public more involved in science and debates about science. My supervisor, Pete Barham, was doing lots of this himself, and he helped and encouraged me enormously. I can't thank him enough. Did you consider teaching as a career? Well I like having the carpet whipped away from

How likely are older people to take up different falls prevention activities?

OpenAIRE

Yardley, Lucy; Kirby, Sarah; Ben-Shlomo, Yoav Ben; Gilbert, Rebecca; Whitehead, Sarah; Todd, Chris

2008-01-01

Objective: To determine the extent to which older people are willing to engage in different falls preventionactivities, and how this may vary in different sectors of the older population.Methods: A survey sent to patients aged over 54 in ten general practices in the Southampton, Bristol andManchester areas of the UK in 2006 yielded 5,440 respondents. The survey assessed willingness to attendclasses of strength and balance training (SBT), carry out SBT at home, or accept support to reduce home...

The language of the unheard: Social media and riot subculture/s

OpenAIRE

Rice, L.

2017-01-01

This chapter examines the relationships between social media, subculture identity and riots. In 2011 riots in Bristol (UK) attracted global media coverage. These riots were one of the first in the UK where social media played a significant role. Social media was used during the riot to disseminate information about when and where riots were taking pace and how the events were developing. The emergence of a ‘riot subculture’ that uses social media has become an easy target for politicians look...

LOS Throughput Measurements in Real-Time with a 128-Antenna Massive MIMO Testbed

OpenAIRE

Harris, Paul; Zhang, Siming; Beach, Mark; Mellios, Evangelos; Nix, Andrew; Armour, Simon; Doufexi, Angela; Nieman, Karl; Kundargi, Nikhil

2017-01-01

This paper presents initial results for a novel 128-antenna massive Multiple-Input, Multiple- Output (MIMO) testbed developed through Bristol Is Open in collaboration with National Instruments and Lund University. We believe that the results presented here validate the adoption of massive MIMO as a key enabling technology for 5G and pave the way for further pragmatic research by the massive MIMO community. The testbed operates in real-time with a Long-Term Evolution (LTE)-like PHY in Time Div...

In-Process Analysis Program for the Isolock sampler at the Gunite and Associated Tanks, Oak Ridge National Laboratory, Oak Ridge, Tennessee

International Nuclear Information System (INIS)

1998-05-01

The In-Process Analysis Program documents the requirements for handling, transporting, and analyzing waste slurry samples gathered by the Bristol Isolock slurry sampler from the Gunite and Associated Tanks at Oak Ridge National Laboratory in Oak Ridge, Tennessee. Composite samples will be gathered during sludge retrieval operations, labeled, transported to the appropriate laboratory, and analyzed for physical and radiological characteristics. Analysis results will be used to support occupational exposure issues, basic process control management issues, and prediction of radionuclide flow

Dosimetric studies in the Institute of Energetic Techniques from the Polytechnic University of Catalunna

International Nuclear Information System (INIS)

Ortega, X.; Ginjaume, M.

1998-01-01

The University Institute for Energetic Techniques from the Polytechnic University of Catalunya in Barcelona develops its activities in the field of dosimetry in two main facilities which are: a calibration laboratory and a thermoluminescent dosimetry laboratory. Activities can be divided into three areas of action based on radiation levels analyzed: environmental, operational and clinical dosimetry

Exploring the Misrepresentation of Nigerian Women in Technical and Vocational Education in Polytechnic Institution

Directory of Open Access Journals (Sweden)

Robert Akor

2014-10-01

Full Text Available Nigerian government is making frantic efforts to drive her economy by laying emphasis on technical and vocational education to enable her compete favorably in the global market. Emphasis of government is in Polytechnic education where skills for self-reliant and economic growth are a priority. However, women are not embracing this opportunity by participating in the program that will equip them with skills and contribute to national development. In all 14 female participants were purposefully selected from Polytechnic. Phenomenological methodology was adopted and data collected were transcribed and analyzed. Results from the study include math/science phobia, perceived social support, and contextual roles among reasons for misrepresentation of women in technical and vocational education. Unless women have increased access to technical and vocational education in order to build diverse technical skills their vulnerability to unemployment and poverty will be on the rise. The findings of this study will guide stakeholders to develop a framework for improving the enrollment of women in this field. Keywords: women, technical and vocational education, self-reliant and unemployment

Effect of Apixaban Versus Warfarin Use on Health Care Resource Utilization and Costs Among Elderly Patients with Nonvalvular Atrial Fibrillation.

Science.gov (United States)

Deitelzweig, Steven; Luo, Xuemei; Gupta, Kiran; Trocio, Jeffrey; Mardekian, Jack; Curtice, Tammy; Lingohr-Smith, Melissa; Menges, Brandy; Lin, Jay

2017-11-01

associated with less HCRU and lower total all-cause health care costs and costs for bleeding- and stroke-related medical services, but greater pharmacy costs, among elderly NVAF patients. This study was sponsored by Pfizer and Bristol-Myers Squibb. Deitelzweig is a consultant for Pfizer and Bristol-Myers Squibb and has served on their advisory boards and received speaker fees. Deitelzweig also serves as consultant and advisory board member to Portola and Janssen. Luo, Trocio, and Mardekian are employees of Pfizer and own stock in the company. Gupta and Curtice are employees of Bristol-Myers Squibb and own stock in the company. Lingohr-Smith, Menges, and Lin are employees of Novosys Health, which received research funds from Pfizer and Bristol-Myers Squibb to conduct this study and develop the manuscript. Study concept and design were primarily contributed by Deitelzweig, Luo, and Gupta, along with Trocio, Mardekian, Curtice, and Lin. Lin, Menges, and Lingohr-Smith took the lead in data collection, with assistance from the other authors. Data interpretation was performed by Deitelzweig, Menges, and Lin, with assistance from the other authors. The manuscript was written by Lingohr-Smith and Menges, along with the other authors, and revised by all the authors. Some aspects of this study were presented at the American Heart Association Scientific Sessions in New Orleans, Louisiana, November 12-16, 2016.

Sharing of Rensselaer Polytechnic Institute Reactor Critical Facility (RCF)

International Nuclear Information System (INIS)

1995-01-01

The RPI Reactor Critical Facility (RCF) operated successfully over the period fall 1994 - fall 1995. During this period, the RCF was used for Critical Reactor Laboratory spring 1995 (12 students); Reactor Operations Training fall 1994 (3 students); Reactor Operations Training spring 1995 (3 students); and Reactor Operations Training fall 1995 (3 students). Thirty-two Instrumentation and Measurement students used the RCF for one class for hands-on experiments with nuclear instruments. In addition, a total of nine credits of PhD thesis work were carried out at the RCF. This document constitutes the 1995 Report of the Rensselaer Polytechnic Institute's Reactor Critical Facility (RCF) to the USNRC, to the USDOE, and to RPI management

Pour en lire plus : Dark Tourism and Place Identity

OpenAIRE

DIAZ, Jérémy

2016-01-01

Quatre ans après The Darker Side of Travel: The Theory and Practice of Dark Tourism (2009, Bristol, Channel View Publications), dirigé par Richard Sharpley et Philip R. Stone, l’ouvrage collectif Dark Tourism and Place Identity: Managing and Interpreting Dark Places constitue une autre contribution remarquable à la compréhension scientifique du dark tourism. À l’intersection des travaux sur l’identité du lieu et le dark tourism, ce livre propose une approche internationale de l’objet dans une...

Evaluation of flipped teaching

OpenAIRE

Henderson, K.; Hobbs, C.; Last, K.

2017-01-01

We report on our evaluation of flipping the classroom for two modules: a compulsory first year calculus module and an optional second year coding theory module taken by Mathe-matics students at the University of the West of England, Bristol (UWE). Flipped teaching is a change to the traditional lecture model used in universities for hundreds of years. In the traditional model the lecturer is in charge of the class and largely dictates the content and pace at which this is delivered. The idea ...

Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

DEFF Research Database (Denmark)

Deacon, Carolyn F; Holst, Jens J

2009-01-01

Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. Saxagliptin is metabolized...... a neutral effect on body weight and dose adjustment because of age, gender, or hepatic impairment is not necessary. Saxagliptin is being co-developed by Bristol-Myers-Squibb (New York, NY, USA) and AstraZeneca (Cheshire, UK), and is currently undergoing regulatory review....

Characteristics of particulate matter collected at an urban background site and a roadside site in Birmingham, United Kingdom

OpenAIRE

Taiwo, Adewale M.

2017-01-01

ABSTRACT This study was conducted to investigate the compositional characteristics of particulate matter (PM) collected both at an urban background site (Elms Road observational site, EROS) and a roadside site (Bristol Road observational site, BROS). PM samples were collected at the receptor sites between March 28 and April 11, 2012. Observed parameters included water-soluble ions (Cl-, NO- 3, SO4 2-, Na+, NH4 +, K+, Mg2+, Ca2+) and trace metals (V, Al, Cr, Mn, Fe, Zn, Cu, Sb, Ba, Pb). Result...

Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill

OpenAIRE

Brandler, William M.; Morris, Andrew P.; Evans, David M.; Scerri, Thomas S.; Kemp, John P.; Timpson, Nicholas J.; St Pourcain, Beate; Smith, George Davey; Ring, Susan M.; Stein, John; Monaco, Anthony P.; Talcott, Joel B.; Fisher, Simon E.; Webber, Caleb; Paracchini, Silvia

2013-01-01

This work was supported by the University of St Andrews, the UK Medical Research Council (grant number G0800523/86473 to SP), the Max Plank Society, and the the EU (Neurodys, 018696). Genotyping at the Wellcome Trust Centre for Human Genetics was supported by the Wellcome Trust (090532/Z/ 09/Z) and a Medical Research Council Hub Grant (G0900747 91070). Core support for ALSPAC was provided by the UK Medical Research Council and the Wellcome Trust (092731) and the University of Bristol. SP is a...

Assessment of Commonly Used Pediatric Stool Scales: A pilot study

OpenAIRE

Saps, M.; Nichols-Vinueza, D.; Dhroove, G.; Adams, P.; Chogle, A.

2013-01-01

Background: The Bristol Stool Form Scale (BSFS) and a modified child-friendly version (M-BSFS) are frequently used in clinical practice and research. These scales have not been validated in children. 3-D stool scale models may be better adapted to the child's development. Aims: To assess the usefulness of the BSFS, M-BSFS, and a newly developed 3-D stool scale in children. Methods: Fifty children were asked to rank the picture cards of the BSFS and 3-D models from hardest to softest and...

Understanding Financial Viability of Urban Consolidation Centres: Regent Street (London), Bristol/Bath & Nijmegen

NARCIS (Netherlands)

van Duin, Ron; van Dam, T; Wiegmans, B.; Tavasszy, L.A.

2016-01-01

The concept of an urban consolidation centre (UCC) has been extensively researched. Despite the potential positive environmental and social impact, the main obstacle remains the lack of a sustainable business model. The goal of this paper is to understand how to organize UCC viability as a concept

Pathophysiology of white matter perfusion in Alzheimer's disease and vascular dementia.

Science.gov (United States)

Barker, Rachel; Ashby, Emma L; Wellington, Dannielle; Barrow, Vivienne M; Palmer, Jennifer C; Kehoe, Patrick G; Esiri, Margaret M; Love, Seth

2014-05-01

Little is known about the contributors and physiological responses to white matter hypoperfusion in the human brain. We previously showed the ratio of myelin-associated glycoprotein to proteolipid protein 1 in post-mortem human brain tissue correlates with the degree of ante-mortem ischaemia. In age-matched post-mortem cohorts of Alzheimer's disease (n = 49), vascular dementia (n = 17) and control brains (n = 33) from the South West Dementia Brain Bank (Bristol), we have now examined the relationship between the ratio of myelin-associated glycoprotein to proteolipid protein 1 and several other proteins involved in regulating white matter vascularity and blood flow. Across the three cohorts, white matter perfusion, indicated by the ratio of myelin-associated glycoprotein to proteolipid protein 1, correlated positively with the concentration of the vasoconstrictor, endothelin 1 (P = 0.0005), and negatively with the concentration of the pro-angiogenic protein, vascular endothelial growth factor (P = 0.0015). The activity of angiotensin-converting enzyme, which catalyses production of the vasoconstrictor angiotensin II was not altered. In samples of frontal white matter from an independent (Oxford, UK) cohort of post-mortem brains (n = 74), we confirmed the significant correlations between the ratio of myelin-associated glycoprotein to proteolipid protein 1 and both endothelin 1 and vascular endothelial growth factor. We also assessed microvessel density in the Bristol (UK) samples, by measurement of factor VIII-related antigen, which we showed to correlate with immunohistochemical measurements of vessel density, and found factor VIII-related antigen levels to correlate with the level of vascular endothelial growth factor (P = 0.0487), suggesting that upregulation of vascular endothelial growth factor tends to increase vessel density in the white matter. We propose that downregulation of endothelin 1 and upregulation of vascular endothelial growth factor in the context

In vitro placental model optimization for nanoparticle transport studies

Directory of Open Access Journals (Sweden)

Cartwright L

2012-01-01

Full Text Available Laura Cartwright1, Marie Sønnegaard Poulsen2, Hanne Mørck Nielsen3, Giulio Pojana4, Lisbeth E Knudsen2, Margaret Saunders1, Erik Rytting2,51Bristol Initiative for Research of Child Health (BIRCH, Biophysics Research Unit, St Michael's Hospital, UH Bristol NHS Foundation Trust, Bristol, UK; 2University of Copenhagen, Faculty of Health Sciences, Department of Public Health, 3University of Copenhagen, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics and Analytical Chemistry, Copenhagen, Denmark; 4Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari Venice, Venice, Italy; 5Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USABackground: Advances in biomedical nanotechnology raise hopes in patient populations but may also raise questions regarding biodistribution and biocompatibility, especially during pregnancy. Special consideration must be given to the placenta as a biological barrier because a pregnant woman's exposure to nanoparticles could have significant effects on the fetus developing in the womb. Therefore, the purpose of this study is to optimize an in vitro model for characterizing the transport of nanoparticles across human placental trophoblast cells.Methods: The growth of BeWo (clone b30 human placental choriocarcinoma cells for nanoparticle transport studies was characterized in terms of optimized Transwell® insert type and pore size, the investigation of barrier properties by transmission electron microscopy, tight junction staining, transepithelial electrical resistance, and fluorescein sodium transport. Following the determination of nontoxic concentrations of fluorescent polystyrene nanoparticles, the cellular uptake and transport of 50 nm and 100 nm diameter particles was measured using the in vitro BeWo cell model.Results: Particle size measurements, fluorescence readings, and confocal microscopy indicated both cellular uptake of

The impact of the customer relationship management on organizational productivity, customer trust and satisfaction by using the structural equation model: A study in the Iranian hospitals.

Science.gov (United States)

Yaghoubi, Maryam; Asgari, Hamed; Javadi, Marzieh

2017-01-01

One of the challenges in the fiercely competitive space of health organizations is responding to customers and building trust and satisfaction in them in the shortest time, with best quality and highest productivity. Hence the aim of this study is to survey the impact of customer relationship management (CRM) on organizational productivity, customer loyalty, satisfaction and trust in selected hospitals of Isfahan (in Iran). This study is a correlation descriptive research. Study population was the nurses in selected hospitals of Isfahan and the sampling has been conducted using stratified random method. Data collection tool is a researcher-made questionnaire of CRM and its effects (organizational productivity, customer loyalty, satisfaction and trust) which its validity and reliability has been confirmed by researchers. Structural equation method was used to determine the impact of variables. Data analysis method was structural equation modeling and the software used was SPSS version 16 (IBM, SPSS, 2007 Microsoft Corp., Bristol, UK) and AMOS version 18 (IBM, SPSS, 2010 Microsoft Corp, Bristol, UK). Among the dimensions of CRM, diversification had the highest impact (0.83) and customer acquisition had the lowest (0.57) CRM, had the lowest impact on productivity (0.59) and the highest effect on customer satisfaction (0.83). For the implementation of CRM, it is necessary that the studied hospitals improve strategies of acquiring information about new customers, attracting new customers and keeping them and communication with patients outside the hospital and improve the system of measuring patient satisfaction and loyalty.

The crescent sign: dissociation of the polyethylene liner from a modular acetabular component in total hip arthroplasty

International Nuclear Information System (INIS)

White, S.P.; Blom, A.W.; Lee, M.; Smith, E.J.

2005-01-01

To study whether there was a common pattern of clinical symptoms, signs and radiographic features for the dissociation of the polyethylene liner from an acetabular component and to postulate reasons for these features. Retrospective study of notes and radiographs of cases of revision hip arthroplasty for polyethylene liner dissociation of the cementless Harris-Galante I porous-coated acetabular component (Zimmer Inc, Warsaw, IN) at the Avon Orthopaedic Centre, Bristol, UK and St. Mary's Hospital, Bristol, UK between 1995 and 2004. Patients were contacted to confirm preoperative symptoms. Nine cases of late polyethylene liner dissociation of this prosthesis have been revised in these institutions. All patients presented with a reduction in mobility, groin pain and limp. Eight patients reported an audible noise on hip movement. In all cases, radiographs showed radiolucency medial to the femoral neck in association with an eccentrically placed femoral head showing contact with the acetabular metal shell, which we have termed the ''crescent sign.'' There is a typical clinical presentation in this study. The diagnosis can be made from a single anteroposterior pelvic radiograph without the need for previous films for comparison, or the need for arthrography. Clinicians should look specifically for the crescent sign when an eccentrically placed femoral head has been noted, in order to differentiate the more unusual diagnosis of dissociation from that of polyethylene wear. Early revision surgery can prevent damage to the femoral head and metal acetabular shell, thus reducing the complexity of revision surgery. (orig.)

Developing quality indicators for community services: the case of district nursing.

Science.gov (United States)

Davies, Philippa; Wye, Lesley; Horrocks, Sue; Salisbury, Chris; Sharp, Debbie

2011-01-01

Quality indicators exist for the acute and primary care sectors in the National Health Service (NHS), but until recently little attention has been given to measuring the quality of community services. The innovative project described in this paper attempted to address that gap. To produce a framework for developing quality indicators for Bristol Community Health services. To develop a set of initial indicators for Bristol Community Health services using the proposed framework. After familiarising ourselves with community services and NHS policy, gathering the views of stakeholders and consulting the literature on quality indicators, we designed a framework for indicator development, using the 'test' case of the district nursing service. The long list of possible indicators came from best practice guidelines for wound, diabetes and end of life care, the three conditions most commonly treated by district nurses. To narrow down this list we surveyed and held workshops with district nurses, interviewed service users by telephone and met with commissioners and senior community health managers. The final set of quality indicators for district nurses included 23 organisational and clinical process and outcome indicators and eight patient experience indicators. These indicators are now being piloted, together with two potential tools identified to capture patient reported outcomes. Developing quality indicators for community services is time consuming and resource intensive. A range of skills are needed including clinical expertise, project management and skills in evidence-based medicine. The commitment and involvement of front-line professionals is crucial.

A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase

Directory of Open Access Journals (Sweden)

Christmas DM

2011-07-01

Full Text Available David M Christmas, JP Potokar, Simon JC DaviesAcademic Unit of Psychiatry, School of Social and Community Medicine, University of Bristol, Bristol, UK A presentation relating to this manuscript was made by Dr David Christmas at the 9th International Meeting on Clinical Pharmacology in Psychiatry (9th IMCPP in Copenhagen, Denmark in September 2010Abstract: This article highlights the evidence linking depression to increased inflammatory drive and explores putative mechanisms for the association by reviewing both preclinical and clinical literature. The enzyme indoleamine 2,3-dioxygenase is induced by proinflammatory cytokines and may form a link between immune functioning and altered neurotransmission, which results in depression. Increased indoleamine 2,3-dioxygenase activity may cause both tryptophan depletion and increased neurotoxic metabolites of the kynurenine pathway, two alterations which have been hypothesized to cause depression. The tryptophan-kynurenine pathway is comprehensively described with a focus on the evidence linking metabolite alterations to depression. The use of immune-activated groups at high risk of depression have been used to explore these hypotheses; we focus on the studies involving chronic hepatitis C patients receiving interferon-alpha, an immune activating cytokine. Findings from this work have led to novel strategies for the future development of antidepressants including inhibition of indoleamine 2,3-dioxygenase, moderating the cytokines which activate it, or addressing other targets in the kynurenine pathway.Keywords: depression, inflammation, indoleamine 2,3-dioxygenase, kynurenine, serotonin, tryptophan

Particle Physics and Astronomy Research Council (PPARC) members, United Kingdom, visiting the ATLAS semiconductor tracker (SCT) module tests.

CERN Multimedia

Patrice Loïez

2002-01-01

Photo 01: Mr Peter Warry, PPARC Chairman, Victrex Plc, United Kingdom visiting the ATLAS SCT module tests with Dr Joleen Pater, SCT (Manchester). Photo 02: PPARC Council Members, United Kingdom, visiting the ATLAS SCT module tests. L.t to r.: Mrs Judith Scott, Chief Executive, British Computer Society, Prof. George Efstathiou, Institute of Astronomy, University of Cambridge, Mr Peter Warry, PPARC Chairman, Victrex Plc, Prof. Martin Ward, Director X-Ray Astronomy, of Leicester, Prof. James Stirling, Director, Institute for Particle Physics Phenomenology, University of Durham and Prof. Brian Foster, University of Bristol.

The current status of immunotoxins: an overview of experimental and clinical studies as presented at the Third International Symposium on Immunotoxins.

Science.gov (United States)

Uckun, F M; Frankel, A

1993-02-01

The Third International Symposium on Immunotoxins was held on June 19-21, 1992 in Orlando, Florida. This symposium was sponsored by NATO, NIH, Pierce Chemical Company, Walt Disney Cancer Institute at Florida Hospital, Duke Comprehensive Cancer Center, Xoma, Immunogen, Seragen, Bristol-Myers Squibb, Chiron, Ortho Biotech, Upjohn, Merck Sharp & Dohme Research Laboratories, Abbot Laboratories, Lilly Research Laboratories, and Evans & Sutherland. The Pierce Immunotoxin Award which recognizes outstanding contributions to immunotoxin research and development, was presented to Drs David FitzGerald, Fatih Uckun, David Eisenberg, and Ira Wool, for their contributions to the immunotoxin field.

Paclitaxel and doxorubicin in metastatic breast cancer

DEFF Research Database (Denmark)

Gehl, J; Boesgaard, M; Paaske, T

1996-01-01

For the past decades the anthracyclines have been regarded as among the most active drugs for the treatment of metastatic breast cancer. However, the 5-year survival rate in patients with stage IV breast cancer continues to be below 20%, and new active drugs and drug combinations clearly must...... be explored. Paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) has been demonstrated to be highly effective in treating patients with advanced breast cancer, including those with anthracycline-resistant breast cancer, a fact that has led to efforts to combine paclitaxel and anthracyclines...

Geology and ore deposits of the Pioche district, Nevada

Science.gov (United States)

Westgate, L.G.; Knopf, Adolph

1932-01-01

LOCATION AND SURFACE FEATURES The Bristol Range, Highland, and Ely Range quadrangles make up the larger part of a. rectangular area 35 miles north and south by 24 miles east and west, which lies 19 miles west of the Nevada-Utah line and about 250 miles southwest of Salt Lake City. The district lies within the Great Basin, a semiarid region of alternating mountain ranges and intermontane plains floored largely by outwash from the mountains. The plain, which slopes away from the ranges, stands between 4,700 and 6,000 feet above the sea. The Bristol and Highland Ranges, which are separated only by a low gap, form an almost continuous north-south range that rises about 2,500 feet above the highest part of the surrounding plain, to general altitudes of 8,000 to 9,000 feet, though the highest point, Highland Peak, reaches 9,395 feet. A lower range, the Ely Range, with a northwesterly trend, lies farther east and nearly in touch with the Bristol-Highland Range. The town of Pioche lies midway on the. eastern foot of the Ely Range. ROOKS OF THE PIOOHB REGION The rocks of the ranges are Paleozoic sediments, Tertiary (?) lavas and intrusive rocks, and Pliocene (?) tuffs. The Paleozoic sediments have a total thickness of nearly 18,000 feet. Over 8,000 feet of the Cambrian has been measured without reaching its base. The lowest Cambrian formation is a quartzite, of which only the upper 1,500 feet is exposed, and this is followed by 1,200 feet of shale, 400 feet of limestone, aoid 150 feet of shale. Above this second shale the upper three-fourths of the Cambrian consists of limestone and dolomitic limestone. It is in the quartzite and in the limestone interbedded in and bounding the shales that the main ore bodies of the district have been found. Above the Cambrian comes 1,795 feet of Ordovician limestone, with some interbedded dolomite and with a 50-foot quartzite a, third of the way down from the top; 75 feet of Silurian dolomite; 3,000 feet of Middle Devonian dolomite with

An Empirical Study on Alleviating Career English Writing Anxiety through Cooperative Learning in a Chinese Polytechnic Institute

Science.gov (United States)

Jiang, Dongmei

2016-01-01

This study investigated the effect of cooperative learning on writing anxiety alleviation through a pre-test/post-test assessment. 120 EFL learners from a Chinese polytechnic institute were assigned into two groups: one experimental (cooperative writing) and the other comparison (solitary writing). Results revealed that cooperative learning…

SoSTeM Model Development for Application of Soft Skills to Engineering Students at Malaysian Polytechnics

Science.gov (United States)

Esa, Ahmad; Padil, Suhaili; Selamat, Asri; Idris, Mohammad Talha Mohamed

2015-01-01

Soft skills are some of the skills needed to ensure that graduates fulfill the needs of the job market. Until 2010, almost 30% of unemployed graduates in Malaysia are technical graduates and one third comes are graduates from polytechnic. Most engineering graduates are proficient in technical skills but lack in soft skills. The lack of relevant…

Language Needs of ICT Students in Malaysian Polytechnics

Directory of Open Access Journals (Sweden)

Shahiza Ahmad Zainuddin

2012-07-01

Full Text Available This study investigates and come out with suggestions to engage the needs of the students, lecturers and industrial trainers. The findings promote better understanding of all the stakeholders thus are used to come out with suggestions to enhance the ESP programme practiced at polytechnics. The main research questions are: What are the language needs of ICT students and How to meet the needs of all the stakeholders. A case study is conducted and aimed to identify the language needs of students who are in the Information Technology Diploma programme. A mixed method research is opted to analyze the data. Mixed method research describes and explains the second language needs of the respondents. Qualitative and quantitative data is collected in phases and involved three types of respondents: diploma in ICT students, language and content lecturers and industrial trainers. The findings of this study may add knowledge in developing human capital in Malaysia especially in relation to English competency in ICT discipline.

A research and professional approach to independent work in Cuban polytechnic school

Directory of Open Access Journals (Sweden)

Navarro, Zita Elaine

2015-09-01

Full Text Available The potentials and shortcomings of independent work in the teachers of polytechnic school training process are an indication of the need of devising a methodology based on a research and professional approach linked to professional performance. The integrative character of academic and non-academic tasks in the process is examined from its planning stage from the perspective of a diversity of professional performance contexts. The findings were appraised by means of expertise valuation and by means of a controlled experiment. Palabras clave: Trabajo independiente, enfoque profesional, enseñanza técnica y profesional.

Safety Evaluation Report, related to the renewal of the operating license for the critical experiment facility of the Rensselaer Polytechnic Institute (Docket No. 50-225)

International Nuclear Information System (INIS)

1983-10-01

This Safety Evaluation Report for the application filed by the Rensselaer Polytechnic Institute (RPI) for a renewal of operating license CX-22 to continue to operate a critical experiment facility has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. The facility is owned and operated by Rensselaer Polytechnic Institute and is located at a site in the city of Schenectady, New York. The staff concludes that this critical facility can continue to be operated by RPI without endangering the health and safety of the public

Safety evaluation report related to the renewal of the operating license for the Worcester Polytechnic Institute open-pool training reactor, Docket No. 50-134

International Nuclear Information System (INIS)

1982-12-01

This Safety Evaluation Report for the application filed by the Worcester Polytechnic Institute (WPI) for a renewal of Operating License R-61 to continue to operate the WPI 10-kW open-pool training reactor has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. The facility is owned and operated by the Worcester Polytechnic Institute and is located on the WPI campus in Worcester, Worcester County, Massachusetts. The staff concludes that the reactor facility can continue to be operated by WPI without endangering the health and safety of the public

An Analysis of Female Lecturers' Participation in Civil Engineering Research and Development Activities at One Polytechnic in Zimbabwe

Science.gov (United States)

Chikuvadze, Pinias; Matswetu, Vimbai Sharon; Mugijima, Samuel

2015-01-01

This study sought to explore female lecturers' participation in civil engineering research and development activities at one polytechnic in Zimbabwe. Case study design was chosen for this study to make predictions, narration of events, comparisons and drawing of conclusions. The female lecturers were purposively sampled to participate in the…

The impact of the customer relationship management on organizational productivity, customer trust and satisfaction by using the structural equation model: A study in the Iranian hospitals

Science.gov (United States)

Yaghoubi, Maryam; Asgari, Hamed; Javadi, Marzieh

2017-01-01

Context: One of the challenges in the fiercely competitive space of health organizations is responding to customers and building trust and satisfaction in them in the shortest time, with best quality and highest productivity. Hence the aim of this study is to survey the impact of customer relationship management (CRM) on organizational productivity, customer loyalty, satisfaction and trust in selected hospitals of Isfahan (in Iran). Materials and Methods: This study is a correlation descriptive research. Study population was the nurses in selected hospitals of Isfahan and the sampling has been conducted using stratified random method. Data collection tool is a researcher-made questionnaire of CRM and its effects (organizational productivity, customer loyalty, satisfaction and trust) which its validity and reliability has been confirmed by researchers. Structural equation method was used to determine the impact of variables. Data analysis method was structural equation modeling and the software used was SPSS version 16 (IBM, SPSS, 2007 Microsoft Corp., Bristol, UK) and AMOS version 18 (IBM, SPSS, 2010 Microsoft Corp, Bristol, UK). Results: Among the dimensions of CRM, diversification had the highest impact (0.83) and customer acquisition had the lowest (0.57) CRM, had the lowest impact on productivity (0.59) and the highest effect on customer satisfaction (0.83). Conclusions: For the implementation of CRM, it is necessary that the studied hospitals improve strategies of acquiring information about new customers, attracting new customers and keeping them and communication with patients outside the hospital and improve the system of measuring patient satisfaction and loyalty. PMID:28546971

Safe transport of radioactive material. Second edition

International Nuclear Information System (INIS)

1991-01-01

The transport of radioactive material embraces the carriage of radioisotopes for industrial, medical and research uses, and the movement of waste, in addition to consignments of nuclear fuel cycle material. It has been estimated that between eighteen and thirty-eight million package shipments take place each year. On the recommendation of the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), which enjoys wide representations from the Agency's Member States and international organizations, the Secretariat is preparing a training kit comprising this training manual and complementary visual aids. The kit is intended to be the basis for an extensive course on the subject and can be used in whole or in part for inter-regional, regional and even national training purposes. Member States can thus benefit from the material either through training courses sponsored by the Agency, or, alternatively, organized by themselves. As a step towards achieving that goal, the current training manual was compiled using material from the first Inter-Regional Training Course on the Safe Transport of Radioactive material that was held in co-operation with the Nuclear Power Training Centre of the then Central Electricity Generating Board at Bristol, United Kingdom. This Manual was initially published in 1990. On the recommendation of the Agency's Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), the Manual has since been expanded and updated in time for the second Inter-Regional Training Course, that will in 1991 similarly be held in Bristol. Refs, figs, tabs

Efficacy of polyethylene glycol 4000 on constipation of posttraumatic bedridden patients.

Science.gov (United States)

Zhang, Lian-yang; Yao, Yuan-zhang; Wang, Tao; Fei, Jun; Shen, Yue; Chen, Yong-hua; Zong, Zhao-wen

2010-06-01

To investigate the efficacy and safety of polyethylene glycol 4000 on adult patients with functional constipation due to posttraumatic confinement to bed. A total of 201 posttraumatic bedridden patients were studied in this prospective, open-labeled, single-group study. Polyethylene glycol 4000 was administered orally for 14 days and the dosage was adjusted according to the Bristol stool types. Demographic characteristics, disease status, treatment period and factors affecting clinical outcome, especially the concomitant medications, were recorded. After administration of polyethylene glycol 4000, 194 cases (96.52%) showed remission of constipation, including 153 (76.12%) persistent remission. The average defecation frequency increased significantly after treatment and the percentage of patients with stools of normal types (Bristol types 3-5) increased as well. Genders, ages and concomitant medications showed no significant influence on the persistent remission rate. After consecutive treatment for two weeks, patients with slight movement showed a significantly higher remission rate than those without movement (95% vs 80%). At the end of treatment, most accompanying symptoms were relieved obviously. Patients with a medical history of constipation or ever taking laxatives showed a lower remission rate. Sixty cases (29.85%) developed diarrhea during the observational period, among whom 6 (10%) withdrew from the clinical observation voluntarily at the first onset of diarrhea. Two cases suffered from abdominal pain. Polyethylene glycol 4000 has efficacy on functional constipation in posttraumatic bedridden patients. Furthermore, patients with milder symptoms, more movement in bed, and longer duration of treatment but without accompanying symptoms can achieve a higher remission rate.

A holistic method for selecting tidal stream energy hotspots under technical, economic and functional constraints

International Nuclear Information System (INIS)

Vazquez, A.; Iglesias, G.

2016-01-01

Highlights: • A method for selecting the most suitable sites for tidal stream farms was presented. • The selection was based on relevant technical, economic and functional aspects. • As a case study, a model of the Bristol Channel was implemented and validated. - Abstract: Although a number of prospective locations for tidal stream farms have been identified, the development of a unified approach for selecting the optimum site in a region remains a current research topic. The objective of this work is to develop and apply a methodology for determining the most suitable sites for tidal stream farms, i.e. sites whose characteristics maximise power performance, minimise cost and avoid conflicts with competing uses of the marine space. Illustrated through a case study in the Bristol Channel, the method uses a validated hydrodynamics model to identify highly energetic areas and a geospatial Matlab-based program (designed ad hoc) to estimate the energy output that a tidal farm at the site with a given technology would have. This output is then used to obtain the spatial distribution of the levelised cost of energy and, on this basis, to preselect certain areas. Subsequently, potential conflicts with other functions of the marine space (e.g. fishing, shipping) are considered. The result is a selection of areas for tidal stream energy development based on a holistic approach, encompassing the relevant technical, economic and functional aspects. This methodology can lead to a significant improvement in the selection of tidal sites, thereby increasing the possibilities of project acceptance and development.

Leveraging Field Trips in Higher Education for Local Engagement and Impact: An Example from Guatemala

Science.gov (United States)

Riker, J.; Watson, M.; Liu, E. J.; Chigna, G.; Purvis, M.; Naismith, A.

2016-12-01

For over ten years, the University of Bristol (U.K.) has run a field trip for masters students in Natural Hazards in the volcanically active areas of southern Guatemala, home to more than 13 million people. This trip has obvious benefits to its participants - it serves as an immersive and formative experience for students studying volcanic hazard, as well as a springboard for the work of the researchers who lead it. Over the years, it has helped to build strong collaborative ties between academic researchers at Bristol and Guatemala's geologic survey (INSIVUMEH) and emergency management agency (CONRED), facilitating the sharing of data, expertise, and monitoring equipment. The students' regular presence has also enabled infrastructure improvements at Fuego Volcano Observatory, which is itself hosted and partly staffed by the residents of Panimache, a small village just a few miles from the volcano's summit. This field trip does raise challenges, however - an influx of foreign students can draw questions from community members for whom the benefits are indirect (i.e., local job creation or infrastructure improvement) or intangible (i.e., incremental contributions to the body of knowledge regarding volcanic hazard). In this presentation, we'll share stories of our experiences of effective community collaboration in Guatemala. In the spirit of discussion, we would also like to explore the opportunities that exist to better utilise this trip, along with the energy and expertise of its participants, to maximise the positive impact on (and resilience of) local communities, particularly those in the small and largely indigenous villages that populate Fuego Volcano's flanks.

Forming engineers' sociocultural competence: Engineering ethics at tomsk polytechnic university

Science.gov (United States)

Galanina, E.; Dulzon, A.; Schwab, A.

2015-10-01

The aim of the present research is to discuss Tomsk Polytechnic University in respect of forming engineers’ sociocultural competence and teaching engineering ethics. Today international standards of training engineers cover efficient communication skills, ability to understand societal and environment context, professional and ethical responsibility. This article deals with the problem of contradiction between the need to form engineers’ sociocultural competence in Russian higher education institutions in order to meet the requirements of international accreditation organizations and the real capabilities of existing engineering curricula. We have described ethics teaching experience of TPU, studied the engineering master programs of TPU to see how the planned results are achieved. We have also given our recommendations to alter the structure of TPU educational curricula, which can also be applied in other higher education institutions.

BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre.

Science.gov (United States)

Sedgley, Kathleen R; Race, Paul R; Woolfson, Derek N

2016-06-15

BrisSynBio is the Bristol-based Biotechnology and Biological Sciences Research Council (BBSRC)/Engineering and Physical Sciences Research Council (EPSRC)-funded Synthetic Biology Research Centre. It is one of six such Centres in the U.K. BrisSynBio's emphasis is on rational and predictive bimolecular modelling, design and engineering in the context of synthetic biology. It trains the next generation of synthetic biologists in these approaches, to facilitate translation of fundamental synthetic biology research to industry and the clinic, and to do this within an innovative and responsible research framework. © 2016 The Author(s).

Perceptions of pork and modern pig breeding among Danish consumers

DEFF Research Database (Denmark)

Bredahl, Lone; Poulsen, Carsten Stig

2002-01-01

This project report summarises the results of a focus group survey of Danish consumers. This survey was conducted by the MAPP Centre in connection with the project 'Sustainability in the production of pork with improved nutritional and eating quality using strategic feeding in outdoor production...... the Univeristy of Uppsala, the University of Bristol and INRA - INRA as the coordinator of this part of the project. The focus groups were held in Danish following a Danish interview guide, but the results are presented in English in this report for the benefit of the project participants and other interested...

Short outlines of books by Estonian authors / Janika Kronberg, Rutt Hinrikus

Index Scriptorium Estoniae

Kronberg, Janika, 1963-

2006-01-01

Arvustus: Krull, Hasso. Loomise mõnu ja kiri. Tallinn : Kultuurileht, 2006 ; Aleksejev, Tiit. Valge kuningriik. Tallinn : Varrak, 2006 ; Baturin, Nikolai. Sõnajalg kivis. Tallinn : Eesti Raamat, 2006 ; Nõu, Helga. Ood lastud rebasele. Tallinn : Eesti Keele Sihtasutus, 2006 ; Kaus, Jan. Tema. Tallinn : Tuum, 2006 ; Krull, Hasso. Talv. Tallinn : Tuum, 2006 ; Soomets, Triin. Väljas. Tallinn : Tuum, 2006 ; Kareva, Doris. Aja kuju. Tallinn : Verb, 2006 ; Vint, Toomas. Topeltvalguses. Tallinn : Eesti Keele Sihtasutus, 2005 ; Bristol, Piret. Sõud. Tallinn : Eesti Keele Sihtasutus, 2005 ; Valton, Arvo. Taltsutatud lammas : jutud. Tallinn : Kirjastuskeskus, 2005 ; Kivastik, Mart. Külmetava kunstniku portreed. Viinistu triloogia. Tartu : Väike Öömuusika, 2006

New technique for alpha particles detection

International Nuclear Information System (INIS)

Morsy, A.A.; Khattab, F.M.

1998-01-01

Man possesses no biological sensors of ionizing radiation as a consequence he must depend entirely on instrumentation for the detection and measurement of radiation. The recent discovery of the solid state nuclear track detection ( SSNTD ) techniques and its advantages over other dosimeters made them a useful tool for radiation dosimetry. This work is devoted to review and illustrate the application of SSNTD technique in some branches of science and technology specially the newly produced TASTRAK obtained from Track Analysis System Limited, Bristol, UK. The detector is successfully irradiated, chemically etched and calibrated for the aim of the Alpha radiation dosimetry

Don't panic. A guide to tryptophan depletion with disorder-specific anxiety provocation.

Science.gov (United States)

Hood, S D; Bell, C J; Argyropoulos, S V; Nutt, D J

2016-11-01

The 2002 paper "Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine" by Bell and colleagues - reprinted in this issue of the Journal - reports on a study undertaken in the halcyon days of David Nutt's Psychopharmacology Unit at the University of Bristol, England. In this invited commentary authors of the original work discuss the impact of this paper on the field of acute tryptophan depletion research (especially in the field of clinical anxiety disorders) and the development of disorder-specific anxiogenic provocations over the past decade. © The Author(s) 2016.

78 FR 12255 - Airworthiness Directives; Rolls-Royce (1971) Limited, Bristol Engine Division Turbojet Engines

Science.gov (United States)

2013-02-22

...: (202) 493-2251. For service information identified in this AD, contact Rolls-Royce plc, Corporate... received by the closing date and may amend this proposed AD based on those comments. We will post all... this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone...

77 FR 60896 - Drawbridge Operation Regulation; Delaware River, Between Burlington, NJ and Bristol, PA

Science.gov (United States)

2012-10-05

... temporary deviation. The bridge will not be able to open in an emergency during lift cable tension... the operating lift cables. DATES: This deviation is effective from 7 a.m. on October 30, 2012 to 3 p.m... 33 CFR 117.5 and 117.716(b) to facilitate the adjustment of the operational lift cables. The...

Retrospective analysis of drug utilization, health care resource use, and costs associated with IFN therapy for adjuvant treatment of malignant melanoma

Directory of Open Access Journals (Sweden)

Zhang Y

2015-07-01

Full Text Available ≥Ying Zhang,1 Trong Kim Le,1 James W Shaw,2 Srividya Kotapati31Center for Observational Research and Data Sciences, Worldwide Health Economics and Outcomes Research, Bristol-Myers Squibb Research and Development, Hopewell, NJ, USA; 2Worldwide Health Economics and Outcomes Research, Bristol-Myers Squibb Research and Development, Princeton, NJ, USA; 3Worldwide Health Economics and Outcomes Research, Bristol-Myers Squibb Research and Development, Wallingford Center, CT, USABackground: This study examines real-world drug utilization patterns, health care resource use, and costs among patients receiving adjuvant treatment with IFN versus patients receiving no treatment ("observation" for malignant melanoma following surgery.Methods: A retrospective cohort study was conducted using administrative claims from Truven Health Analytics (MarketScan® to identify all adjuvant melanoma patients (aged ≥18 years diagnosed between June 2007 and June 2011 who had a lymph node dissection (ie, index surgery and were treated with IFN or subsequently observed. Health care resource use and costs of services were converted to 2012 US dollars and were evaluated and compared using multivariable regression.Results: Of 1,999 eligible subjects with melanoma surgery claims, 179 (9.0% were treated with IFN and 1,820 (91.0% were observed. The median duration (days and number of doses of IFN therapy were 73 and 36, respectively. Among IFN-treated patients, only 10.6% completed ≥80% of maintenance therapy. The total average cost for patients treated with IFN was US$60,755±$3,972 (n=179; significantly higher than for patients undergoing observation ($31,641±$2,471; P<0.0001. Similar trends were observed when evaluating total cost components, including melanoma-related and non-melanoma–related medical costs. Among the melanoma-related medical costs, outpatient services, including office visits and laboratory testing, represented between 33% and 53% of total costs and

Procedure for the Analysis and Suppliers Selection in the Superior Polytechnic School of Chimborazo

Directory of Open Access Journals (Sweden)

Doris Maribel Maribel Sánchez-Lunavictoria

2015-12-01

Full Text Available The analysis is and selection of suppliers of an institution of higher learning is one of the core activities of the logistics process to ensure the necessary resources to meet the standards of quality required by contemporary university excellence. Therefore the aim of this paper is to develop a process for the evaluation and selection of suppliers Polytechnic Superior School of Chimborazo from the use of multi-criteria evaluation methods. The results contribute to improve the process of decision making, quality and institutional efficiency.

Bacteriological Analysis and Hygine Level of Food Outlets within Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria.

OpenAIRE

Ibrahim TA; Akenroye OM; Osabiya OJ

2013-01-01

The bacteriological quality of three major food outlets in Rufus Giwa Polytechnic, Owo, was assessed using standard bacteriological methods. Swabs of hands of food vendors, table and plates in these outlets were assessed for total bacterial count, total coliform count and total E. coli count. A total of 789 bacterial colonies were isolated from hands of food handlers, tables and plates used for eating in the outlets. Eleven genera of bacteria were isolated and identified, they were; klebsiell...

Combinations of laxatives and green banana biomass on the treatment of functional constipation in children and adolescents: a randomized study.

Science.gov (United States)

Cassettari, Vanessa Mello Granado; Machado, Nilton Carlos; Lourenção, Pedro Luiz Toledo de Arruda; Carvalho, Marry Assis; Ortolan, Erika Veruska Paiva

2018-01-05

Evaluate the effect of combinations of green banana biomass and laxatives in children and adolescents with chronic constipation. This was a randomized study of 80 children and adolescents with functional constipation according to the Rome IV Criteria, who were divided into five groups: (1) green banana biomass alone; (2) green banana biomass plus PEG 3350 with electrolytes; (3) green banana biomass plus sodium picosulfate; (4) PEG 3350 with electrolytes alone; and (5) sodium picosulfate alone. Primary outcome measure was the reduction of the proportion of patients with Bristol Stool Form Scale ratings 1 or 2. Secondary outcome measures were: increase of the proportion of >3 bowel movements/week and reduction of the proportion of fecal incontinence, straining on defecation, painful defecation, blood in stool, abdominal pain, and decreased laxative doses. On consumption of green banana biomass alone, a statistically significant reduction was observed in the proportion of children with Bristol Stool Form Scale rating 1 or 2, straining on defecation, painful defecation, and abdominal pain. Conversely, no reduction was observed in fecal incontinence episodes/week, blood in stool, and no increase was observed in the proportion of children with >3 bowel movements/week. The percentage of children who required decreased laxative dose was high when green banana biomass was associated with sodium picosulfate (87%), and PEG 3350 with electrolytes (63%). Green banana biomass alone and associated with laxatives was well tolerated, and no adverse effects were reported. Green banana biomass is advantageous as an adjunct therapy on functional constipation, mainly for reducing doses of laxatives. Copyright © 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Impact of the alterations in the interstitial cells of Cajal on intestinal motility in post-infection irritable bowel syndrome.

Science.gov (United States)

Yang, Bo; Zhou, Xu-Chun; Lan, Cheng

2015-04-01

The interstitial cells of Cajal (ICC) are basic components of gastrointestinal motility. However, changes in ICC and their role in post‑infection irritable bowel syndrome (PI‑IBS) remain to be elucidated. To observe the impact of alterations in the ICC on intestinal motility in a PI‑IBS mouse model, female C57BL\\6 mice were infected by the oral administration of 400 Trichinella spiralis larvae. The abdominal withdrawal reflex, intestine transportation time (ITT), grain numbers, Bristol scores, wet/dry weights and the percentage water content of the mice feces every 2 h were used to assess changes in the intestinal motor function. The intestines were excised and sectioned for pathological and histochemical examination. These intestines were also used to quantify the protein and mRNA expression of c‑kit. The C57BL\\6 mouse can act as a PI‑IBS model at day 56 post‑infection. Compared with the control mice, the ITT was shorter, the grain numbers, Bristol scores, wet weights and water contents of the mice feces were higher and the dry weights were unchanged in the PI‑IBS mice. The protein and mRNA expression levels of c‑kit were upregulated in the entire PI‑IBS mouse intestines. Following immunohistochemical staining, the increased number of c‑kit‑positive cells were detected predominantly in the submucosa and myenteron. These results suggested that the alterations of the ICC resulted in the changes of the intestinal motility patterns in the PI‑IBS mouse models induced by Trichinella spiralis infection, which may be the main mechanism underlying intestinal motility disorders in PI‑IBS.

Extraction of SelectSecure leads compared to conventional pacing leads in patients with congenital heart disease and congenital atrioventricular block.

Science.gov (United States)

Shepherd, Emma; Stuart, Graham; Martin, Rob; Walsh, Mark A

2015-06-01

SelectSecure™ pacing leads (Medtronic Inc) are increasingly being used in pediatric patients and adults with structural congenital heart disease. The 4Fr lead is ideal for patients who may require lifelong pacing and can be advantageous for patients with complex anatomy. The purpose of this study was to compare the extraction of SelectSecure leads with conventional (stylette-driven) pacing leads in patients with structural congenital heart disease and congenital atrioventricular block. The data on lead extractions from pediatric and adult congenital heart disease (ACHD) patients from August 2004 to July 2014 at Bristol Royal Hospital for Children and the Bristol Heart Institute were reviewed. Multivariable regression analysis was used to determine whether conventional pacing leads were associated with a more difficult extraction process. A total of 57 patients underwent pacemaker lead extractions (22 SelectSecure, 35 conventional). No deaths occurred. Mean age at the time of extraction was 17.6 ± 10.5 years, mean weight was 47 ± 18 kg, and mean lead age was 5.6 ± 2.6 years (range 1-11 years). Complex extraction (partial extraction/femoral extraction) was more common in patients with conventional pacing leads at univariate (P < .01) and multivariate (P = .04) levels. Lead age was also a significant predictor of complex extraction (P < .01). SelectSecure leads can be successfully extracted using techniques that are used for conventional pacing leads. They are less likely to be partially extracted and are less likely to require extraction using a femoral approach compared with conventional pacing leads. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

Impact of Electronic Resources and Usage in Academic Libraries in Ghana: Evidence from Koforidua Polytechnic & All Nations University College, Ghana

Science.gov (United States)

Akussah, Maxwell; Asante, Edward; Adu-Sarkodee, Rosemary

2015-01-01

The study investigates the relationship between impact of electronic resources and its usage in academic libraries in Ghana: evidence from Koforidua Polytechnic & All Nations University College, Ghana. The study was a quantitative approach using questionnaire to gather data and information. A valid response rate of 58.5% was assumed. SPSS…

The Use of Books and Libraries by Part-Time Business Studies Students at a Polytechnic: A Follow-up Study.

Science.gov (United States)

Payne, Philip

To study the effect on library use, of additional expenditure on accounting textbooks needed by part-time business students, a study was conducted in the spring of 1980 at the City of London Polytechnic. Three techniques were used: (1) a questionnaire distributed to all part-time students in the Accountancy Department and, as a control group, all…

Implementation and Effectiveness of Student Affairs Services Program in One Polytechnic College

Directory of Open Access Journals (Sweden)

Jose Ariel R. Ibarrientos

2015-12-01

Full Text Available Descriptive survey using questionnaire was employed to determine the extent of implementation and effectiveness of the Student Affairs Services Program of Camarines Sur Polytechnic Colleges in the Philippines for School Year 2012-2013. Generally, administrators, teachers and students articulated that CSPC’s Student Affairs Services Program was effectively implemented. Of the services provided, Guidance and Counselling and Housing Services show lower significant results in terms of effectiveness. T-test shows that there is no significant difference between its implementation and effectiveness. Significant agreements between the three groups of respondents were identified using the Kendall Coefficient of Concordance. Improvement of the delivery of CSPC’s Student Affairs Services Program will be effective upon adopting the researcher’s Comprehensive Development Plan.

[Dependence of the pharmacokinetics of captopril on the type of adaptation reactions in the organism].

Science.gov (United States)

Udut, V V; Khazanov, V A; Gurto, R V; Borodulina, E V; Postnikova, Iu E

2007-01-01

The dependence of the pharmacokinetic profiles (PhP) of captopril in the phase of adaptation reactions in the organism has been studied within the framework of randomized, comparative, double cross research of bioeqivalency of captopril (Aspharma Co, Anzhero-Sudzhensk) and capoten (Bristol Myers Squibb Co.; official Russian producer, Akrikhin KhimFarmKombinat). It is established that the maximum bioaccessibility and high concentration of captopril in the blood plasma is determined on the background of physiologically optimum reactions of training and in the zone of quiet activation. These characteristics decrease during the reactions of general adaptation syndrome according to the type of increased activation and reactivation.

Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome

Directory of Open Access Journals (Sweden)

Alessandro Aquino

2017-01-01

Full Text Available Pitt-Hopkins Syndrome (PTHS is a rare genetic disorder caused by insufficient expression of the TCF4 gene. Children with PTHS typically present with gastrointestinal disorders and early severe chronic constipation is frequently found (75%. Here we describe the case of a PTHS male 10-year-old patient with chronic constipation in whom Osteopathic Manipulative Treatment (OMT resulted in improved bowel functions, as assessed by the diary, the QPGS-Form A Section C questionnaire, and the Paediatric Bristol Stool Form Scale. The authors suggested that OMT may be a valid tool to improve the defecation frequency and reduce enema administration in PTHS patients.

Role of Ecological Cultural Synthesis in Enhancement of Importance and Competitive Ability of Polytechnic Education in the Southern Far East of the Russian Federation

Science.gov (United States)

Petukhov, V. I.; Golikov, S. Yu; Maiorov, I. S.

2017-11-01

The regional features of polytechnic education development under present-day conditions are considered. The enhanced role of ecological cultural synthesis is proved to be necessary in order to enhance the importance and competitive ability of the polytechnic education in the southern Far East of the Russian Federation. Ecological cultural synthesis is the major condition to turn natural management into the ecologically sparing management of natural resources; it is also a method of a person to learn nature and the mutual relations with nature. It should become a basis for educational programs in the higher schools of the Russian Federation (that may be used with the practical purposes not only in the Russian Federation), and it may promote the search of the national idea, ideological core, and basic principles of further education development in Russia.

Ketamine: stimulating antidepressant treatment?

Science.gov (United States)

Malhi, Gin S; Byrow, Yulisha; Cassidy, Frederick; Cipriani, Andrea; Demyttenaere, Koen; Frye, Mark A; Gitlin, Michael; Kennedy, Sidney H; Ketter, Terence A; Lam, Raymond W; McShane, Rupert; Mitchell, Alex J; Ostacher, Michael J; Rizvi, Sakina J; Thase, Michael E; Tohen, Mauricio

2016-05-01

The appeal of ketamine - in promptly ameliorating depressive symptoms even in those with non-response - has led to a dramatic increase in its off-label use. Initial promising results await robust corroboration and key questions remain, particularly concerning its long-term administration. It is, therefore, timely to review the opinions of mood disorder experts worldwide pertaining to ketamine's potential as an option for treating depression and provide a synthesis of perspectives - derived from evidence and clinical experience - and to consider strategies for future investigations. G.S.M. Grant/research support: National Health Medical Research Council, NSW Health, Ramsay Health, American Foundation for Suicide Prevention, AstraZeneca, Eli Lilly & Co, Organon, Pfizer, Servier, and Wyeth; has been a speaker for Abbott, AstraZeneca, Eli Lilly & Co, Janssen Cilag, Lundbeck, Pfizer, Ranbaxy, Servier, and Wyeth; consultant: AstraZeneca, Eli Lilly & Co, Janssen Cilag, Lundbeck, and Servier. M.A.F. Grant support: AssureRx, Janssen Research & Development, Mayo Foundation, Myriad, National Institute of Alcohol Abuse and Alcoholism (NIAAA), National Institute of Mental Health (NIMH), Pfizer. Consultant (Mayo): Janssen Research & Development, LLC, Mitsubishi Tanabe Pharma Corporation, Myriad Genetics, Neuralstem Inc., Sunovion, Supernus Pharmaceuticals, Teva Pharmaceuticals. CME/travel support: American Physician Institute, CME Outfitters. Financial interest/Mayo Clinic 2016: AssureRx. S.H.K. Grant/research support: Brain Canada, Bristol Meyer Squibb, CIHR, Janssen, Johnson & Johnson, Lundbeck, Ontario Brain Institute, Pfizer, Servier, St. Jude Medical, Sunovion. T.A.K. Grant/research support (through Stanford University): Sunovion Pharmaceuticals and Merck & Co., Inc.; consultant/advisory board bember: Allergan, Inc., Janssen Pharmaceuticals, Myriad Genetic Laboratories, Inc., and Sunovion Pharmaceuticals; lecture honoraria (not Speaker's Bureau payments): Glaxo

Multimedia and security: Workshop at ACM Multimedia '98, Bristol, U.K., September 12 - 13, 1998

OpenAIRE

Dittmann, J.; Wohlmacher, P.; Horster, P.; Steinmetz, R.

1998-01-01

In this paper we describe the most important security requirements, which must be fulfilled by today's IT-systems, and the security measures used to satisfy these requirements. These security measures are based on modern cryptographic mechanisms as well as on security infrastructures. Regarding data security and communication security in particular in the field of multimedia, the requirements on security increase. If and in which way the discussed security mechanisms can be applied to multime...

Gentzler, Edwin. Translation, hypertext, and creativity: Contemporary translation theories. Bristol: Multilingual Matters, 2001. 232 p.

Directory of Open Access Journals (Sweden)

Davi S. Gonçalves

2018-01-01

Full Text Available Contemporary translation theories (Gentzler,2001 provides readers with a thorough historical analysis of how the notion of creativity and autonomy in what regards reading has been transformed – as well as regarding its influence towards the idea of translation. The place occupied by the translator is a place between spaces; a fluid locale where any concreteness has melted. Meaning is thus not graspable or amenable to be tamed; on the contrary, literature is about opening up more space for the wilderness to be (rediscovered. A text is many texts, a hypertext, filled in with narratives that mutually supplement one another, deconstructing and reconstructing meanings; and, within such picture, translation emerges not as an opportunity to resurrect the body of an original text, but as a phantasm of both sameness and uniqueness. What does exist cannot be seen; it is always on the run; meanings surface from liquefied pages, pages that escape our attempt of defining them for good. This is why translation can be taken as metonym: as s/he recreates the original text within the target context, the translator choose to highlight those textual elements that s/he deems relevant – those fragments of the text that have touched and determined his/her reading. The experience of translation, that goes beyond dichotomist standards (e.g. foreign/domestic, equivalent/adapted, etc., is finally taken as a profitable realm for the literary discourse to validate its impalpability. Such shift in the approach towards translation is significant because, even though the process of recreation takes place in every textual practice, tradition has been pressuring translation scholars towards the designing of guidelines and norms that, I dare say, only obstruct the task of translating.

The Effects of Integrating Mobile and CAD Technology in Teaching Design Process for Malaysian Polytechnic Architecture Student in Producing Creative Product

Science.gov (United States)

Hassan, Isham Shah; Ismail, Mohd Arif; Mustapha, Ramlee

2010-01-01

The purpose of this research is to examine the effect of integrating the digital media such as mobile and CAD technology on designing process of Malaysian polytechnic architecture students in producing a creative product. A website is developed based on Caroll's minimal theory, while mobile and CAD technology integration is based on Brown and…

AN ASSESSMENT OF ENTREPRENEURSHIP INTENTION AMONG SUNYANI POLYTECHNIC MARKETING STUDENTS

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Yeboah Asuamah Samuel

2013-01-01

Full Text Available The aim of the paper is to assess the entrepreneurial intention among the students of Sunyani Polytechnic, and also to determine the motivators, and obstacles to entrepreneurial intentions. The study is based on quantitative exploratory survey design. The sample size for the study is 136 comprising of 94 males and 42 females, who were selected by convenient sample method. Primary data were obtained using self designed questionnaire which were administered by the researchers. Data were analysed using percentages, One-way ANOVA. Results indicated that there is high entrepreneurial intention among the respondents. It was also revealed that there are important motivators for intention as well as obstacles to setting up ones firm. The finding again indicated that demographic variables such as gender, age, religion affect responses given by respondents. It is recommended that, future research must be done in the public and private universities to provide support for these findings and also entrepreneurial education must be introduced into the tertiary institutions which are not currently offering entrepreneurship courses.

Undergraduate Confidence When Undertaking Root Canal Treatment and Their Perception of the Quality of Their Endodontic Education

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James Puryer

2016-12-01

Full Text Available The General Dental Council expects graduating dentists to be competent at treating pulpal disease. Previous studies have found dental undergraduates to have low levels of confidence with respect to endodontic treatments. The aim of this study was to investigate the confidence of undergraduate dental students at the University of Bristol when performing root canal treatment, and to investigate their perception of the quality of their endodontic education. An anonymous questionnaire, based upon one used in a 2015 study at Cardiff University, was distributed to all (n = 204 undergraduate students in Years 3–5 at the University of Bristol. The results were analysed using the Statistical Package for the Social Sciences software (SPSS. There was a 59% (n = 120 response rate and a significant (p < 0.01 difference in confidence levels for root canal treatments (RCTs completed between these students. All (100% Year-5 students felt confident in completing anterior RCTs, and 91% felt confident in completing posterior RCTs. The majority (93% of Year-4 students felt confident in completing anterior RCTs, and 77% felt confident in completing posterior RCTs. Over one-half (56% of Year-3 students felt confident in anterior RCTs and 17% in posterior RCTs. With respect to the individual stages of RCT (access cavity, cleaning and shaping of root canal system, and obturation/filling, results showed that there was a significant difference (p < 0.01 in confidence levels between year groups. Many students thought the amount of time spent on endodontic teaching and the quality of teaching to be satisfactory. Improvements suggested for future endodontic teaching included higher numbers of staff supervision and additional endodontic practice on extracted teeth before seeing patients. There was a strong association between students’ clinical experience and their levels of confidence when completing RCT. Increasing the amount of clinical experience of RCTs could

The autophagosome: current understanding of formation and maturation

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Mannack LVJC

2015-02-01

Full Text Available Lilith VJC Mannack, Jon D Lane Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK Abstract: Autophagy is an important and highly conserved catabolic process with roles in development, homeostasis, and cellular stress responses. It describes various distinct pathways for the delivery of cytoplasmic materials (including misfolded protein aggregates and some organelles to the lysosome for degradation and component recycling. The best understood form of autophagy (macroautophagy describes the de novo assembly, maturation, and trafficking of a unique double membrane-bound organelle – the autophagosomes – that sequesters cytoplasmic materials and ultimately merges with the lysosomal compartment to form a degradative autolysosome. To rapidly assemble such a structure in response to stimuli, cells express a family of dedicated autophagy-related (ATG gene products that act sequentially to control membrane events leading first to the nucleation of an isolation membrane or phagophore, followed by phagophore expansion, and sealing to form an autophagosome that traffics to – and ultimately fuses with – the lysosome. These molecules are activated in response to upstream signaling pathways (notably, the mechanistic target of rapamycin [mTOR] pathway, and comprise protein and lipid kinases, putative membrane coats, and unique ubiquitin-like conjugation systems. In concert, a barrage of accessory proteins involved in various membrane trafficking pathways focused on the endosomal compartment are co-opted at the assembly site to facilitate autophagosome biogenesis. Understanding the integrated pathways that coordinate autophagosome assembly at the molecular level will be crucial if we are to realize the potential for autophagy manipulation in future disease therapies. Keywords: autophagy, ATG proteins, lysosome, phagophore, omegasome, autolysosome, membrane trafficking, ULK1, mTOR, PI(3 kinase, PI3P, LIR motif

Doctoral profile of the medical radiation sciences: a baseline for Australia and New Zealand.

Science.gov (United States)

Ekpo, Ernest U; Snaith, Beverly; Harris, Martine A; McEntee, Mark F

2017-09-01

Research is critical to evidence-based practice, and the rapid developments in technology provide opportunities to innovate and improve practice. Little is known about the research profile of the medical radiation science (MRS) profession in Australia and New Zealand (NZ). This study provides a baseline of their doctoral activity. A cross-sectional survey of MRS professionals in Australia and NZ holding a doctorate or undertaking doctoral studies, was performed using an online tool (Bristol Online Survey ® , Bristol, UK). A chain-referral sampling technique was adopted for data collection. An email invitation with a link to the survey was generated and distributed through email and social media. The survey contained questions related to participant demographics, doctoral status, qualification route, funding and employment. There were 63 responses to the survey comprising 50.8% diagnostic radiographers (DRs; n = 32), 23.8% radiation therapists (RTs; n = 15), with the remaining 25.4% (n = 16) equally split between sonographers and nuclear medicine technologists (NMTs). A total of 40 (63.5%) of respondents had completed their doctoral qualification. In NZ, only DRs held a doctoral award constituting 0.3% of DRs and 0.2% of the total registered MRS population. In Australia, there was a greater proportion of doctoral NMTs (n = 8/1098; 0.7%) than RTs (n = 15/2394; 0.6%) and DRs (n = 27/12,001; 0.2%). Similar to other countries, findings show a very small percentage of doctoral MRS professionals in Australia and NZ. Strategies to engage and support individuals in research, up to and beyond doctoral study, need to be embedded in practice. © 2017 The Authors. Journal of Medical Radiation Sciences published by John Wiley & Sons Australia, Ltd on behalf of Australian Society of Medical Imaging and Radiation Therapy and New Zealand Institute of Medical Radiation Technology.

Stratigraphic and compositional complexities of the late Quaternary Lethe tephra in South-central Alaska

Science.gov (United States)

Riehle, J.R.; Ager, T.A.; Reger, R.D.; Pinney, D.S.; Kaufman, D.S.

2008-01-01

Recently discovered Lethe tephra has been proposed as a latest Pleistocene marker bed in Bristol Bay lowland NE to the Cook Inlet region, Alaska, on the basis of correlations involving a single "Lethe average" glass composition. Type deposits in the Valley of Ten Thousand Smokes, however, are chemically heterogeneous-individual lapilli as well as aggregate ash deposits have glass compositions that range from the average mode to much higher SiO2 and K2O. Moreover, a lake-sediment core from the Cook Inlet region contains one ash deposit similar to "Lethe average" and other, closely underlying deposits that resemble a mixture of the average mode and high-Si high-K mode of proximal deposits. Synthesis of previously published radiocarbon ages indicates a major eruption mainly of "Lethe average" mode about 13,000 14C yr BP. As many as six deposits in the Cook Inlet region-five chiefly "Lethe average" mode-range from about 13,000 to 15-16,000 14C yr BP, and an early Holocene deposit in the Bristol Bay lowland extends the minimum age range of Lethe tephra throughout this region to 8000 14C yr BP. Because of the appearance of "Lethe average" composition in multiple deposits spanning thousands of years, we urge caution when using a Lethe-like composition as a basis for inferring a latest Pleistocene age of a tephra deposit in south-central Alaska. Linear variation plots suggest that magma mixing caused the Lethe heterogeneity; multiple magmas were involved as well in other large pyroclastic eruptions such as Katmai (Alaska) and Rotorua (New Zealand). Lethe is an example of a heterogeneous tephra that may be better compared with other tephras by use of plots of individual analytical points rather than by calculating similarity coefficients based on edited data. ?? 2006 Elsevier Ltd and INQUA.

Evaluación de los reactivos hemoclasificadores monoclonales cubanos HEMO CIM ANTI-A y HEMO CIM ANTI-B en pacientes VIH/SIDA Evaluation of the Cuban anti-A Hemo CIM and anti-B Hemo CIM monoclonal hemoclassifiers in HIV/AIDS patients

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Ananidia Rivero

2000-12-01

Full Text Available Se describe un estudio realizado con los hemoclasificadores monoclonales cubanos Hemo CIM anti-A y anti-B producidos por el Centro de Inmunología Molecular (CIM y comercializados por CIMAB S.A, para ser evaluados en pacientes VIH/SIDA. Se analizaron un total de 130 pacientes en el Servicio de Transfusiones del Instituto "Pedro Kourí". Se utilizaron en paralelo los antisueros policlonales de producción nacional (Laboratorios Betera y los reactivos monoclonales comerciales producidos y donados por International Blood Group Reference Laboratory; Bristol, UK. Se demostró que los reactivos Hemo CIM anti-A y Hemo CIM anti-B se comportaron de forma similar a sus homólogos comerciales y policlonales. Al comparar la efectividad de la aglutinación para los 3 reactivos pudimos comprobar que con el reactivo monoclonal, Hemo CIM anti-A y anti-B se obtuvieron los mejores resultados expresados en crucesA study conducted with the Cuban anti-A and anti-B Hemo CIM monoclonal hemoclassifiers produced by the Center of Molecular Immunology (CMI and commercialized by CIMAB S.A. to be evaluated in HIV/AIDS patients is described. 130 patients were analyzed at the Service of Transfusions of "Pedro Kouri" Institute. The polyclonal antisera of national production (Betera Laboratories and the commercial monoclonal reagents produced and donated by the International Blood Group Reference Laboratory; Bristol, UK, were used at the same time. It was proved that the anti-A Hemo CIM and anti-B Hemo CIM reagents behaved similarly to their commercial and polyclonal homologues. On comparing the effectiveness of the agglutination for the 3 reagents, we were able to verify that the best results expressed in crosses were obtained with the anti-A and anti-B Hemo CIM monoclonal reagents

Use of Social Media and Its Impact on Academic Performance of Tertiary Institution Students: A Study of Students of Koforidua Polytechnic, Ghana

Science.gov (United States)

Owusu-Acheaw, M.; Larson, Agatha Gifty

2015-01-01

The study sought to assess students' use of social media and its effect on academic performance of tertiary institutions students in Ghana with a focus on Koforidua Polytechnic students. Questionnaire was used for collecting data. Out of one thousand five hundred and seventy-eight copies of the questionnaire distributed, one thousand five hundred…

Vibration technique for non-destructive testing of carbon fiber reinforced plastic structures

International Nuclear Information System (INIS)

Miller, W.G.

1982-01-01

For nondestructive testing of structures of KFK (carbon fiber reinforced plastics) Adams and a group at the English University of Bristol, Department of Mechanical Engineering have developed a vibrational testing method. It is based on the fact that the decreasing self-oscillations of a structure can be measured in connection with a dynamical analysis at only one particular location of that structure. This way a damage can be localized and be quantized rawly. The mathematical model is simple and for every tested structure only one analysis is needed. Many kinds of damages in structures can be determined and reproduced especially in structures that represent typical cases of application of KFK in air and aerospace industry. (orig.) [de

Professor Peter Higgs: "My Life as a Boson"

CERN Multimedia

CERN. Geneva

2012-01-01

Professor Peter Higgs played a key role in the development of the Standard Model, our current theory of fundamental physics. The search for the Higgs Boson is the centrepiece of the LHC programme at CERN, and the existence of this famously elusive particle is likely to be confirmed or refuted with data currently being collected, using apparatus partly designed at Bristol. Professor Higgs will introduce the ideas of spontaneous symmetry breaking, and discuss how these developed from their application in condensed matter through the earlier work of Yoichiro Nambu and Jeffrey Goldstone, to the work of Robert Brout, Francois Englert and himself in 1964. The subsequent application of these ideas to electroweak theory will be discussed briefly.

Los personajes que parecen etiquetas

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Héctor Rojas Herazo

1967-11-01

Full Text Available La propaganda, como el universo de la ficción, tiene sus personajes clásicos. El hombre del gran bacalao a cuestas en los frascos de emulsión; el perro auditivo en los discos de La Víctor; el cuáquero de las latas de avena; el científico victoriano en la portada de los almanaques Bristol; la vendimiadora del amplio canasto en las cajitas de uvitas de pasa; el dandy trotamundo que, impertinente y risueño con su monóculo en el ojo derecho, que trata de atravesar desde hace ciento cuarenta y cinco años el breve espacio de una marca de whiskey escosés.

Programming languages ​​as a way of training in polytechnics computer. Your Social conditioning

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Raimundo González Fernández

2007-03-01

Full Text Available This article presents a panorama of the necessity the current Cuban society has to form high quality technicians in Computer science, and the social and historical conditions that compromise the existence of the subject “Language of Programming ”inside its study plan, as well as the necessity to upgrade teachers who teach this subject, in Computer Science's Polytechnical School "Carlos Hidalgo Díaz” in Pinar del Río province. Regarding the inadequacies there are in these programs, in the theoretical and methodological order, it is expected that with an intervention strategy consisting on an upgrading course this problem can be solved.

The Taxonomy for Learning, Teaching and Assessing: Current Practices at Polytechnics in Bangladesh and its Effects in Developing Students' Competences

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Faruque A. Haolader

2015-09-01

Full Text Available Polytechnics in Bangladesh endeavour to produce quality graduates for national and international job markets. The quality of graduates depends on several factors. This study examines the implementation process of the polytechnic curriculum with the objectives of determining the current level of practices in learn-ing/teaching material design, in delivering curriculum content, in assessing students and its effect on students' competence development. Data was collected through observation, opinion survey and competence test. Qualitative and quantitative methodologies were used for data interpretation and analysis in this descriptive type of research study. Findings revealed that the learning materials are mainly theory oriented and mostly cover those contents usually common in exams. About half of teachers are aware of the taxonomy for learning, teaching and assessing, but they rarely put importance on it. In the classroom, teachers spend only a little time for delivering content at the level of apply/analyse. However, a significant number of tasks performed in labs are practical and occupation relevant and can be classified at higher levels of the taxonomy. In student assessment, the test-items assess mainly theoretical knowledge at the level of remember. The effect of these practices is reflected in demonstrating student performance in a competence test. The study concludes with some recommendations.

Towards Improving the Strategies of Effective Teaching of Entrepreneurship Development Education Courses to Office Technology and Management Students of Polytechnics in Delta State

Science.gov (United States)

Esene, Robert A.

2015-01-01

This study investigated the strategies and tools for effective teaching of Entrepreneurship Development Education to OTM students of Polytechnics in Delta State. The design of the study was survey. Research question was raised for the study. An instrument which consisted of 70 items was distributed to 30 respondents in the areas covered in the…

The ICT in the Polytechnic Institute of Setúbal The Beginning of a New Phase

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Armando J. Pires

2004-02-01

Full Text Available The main subject of this paper is to present and discuss a technical solution based on the Information and Communication Technologies (ICT that is proposed to be implemented in a Higher Education (HE institution in Portugal. It is believed, that this project will change profoundly the administrative organization and the teaching-learning paradigm inside the Polytechnic Institute of Setúbal (PIS. This project will cover three different and complementary areas: a Wireless LAN area, an Administrative and Informative area and an eLearning area. Other relevant aspects and remarks, regarding eLearning issues, will also be taken into consideration, illustrating the most significant activity of the PIS academic staff in what concerns the eLearning field.

Neutrons field in the neutronic measurements room of the Polytechnic University of Madrid

International Nuclear Information System (INIS)

Vega C, H. R.; Gallego, E.; Lorente, A.; Rubio O, I. P.

2010-09-01

Through of measurements and calculations of a Monte Carlo series has been characterized the neutronic field of the neutronic measurements room of Nuclear Engineering Department of the Polytechnic University of Madrid. The measurements were realized with the Bonner Spheres Spectrometer that allowed establish the spectra on the new stainless steel panel and at different distances measured regarding the source. The values of the speed of environmental equivalent dose were measured with an area monitor Bert hold Lb 6411. Through of Monte Carlo methods was built a detailed model of the room with the panel and the spectra were calculated and, with these the values of the environmental equivalent dose were obtained using the conversion coefficients of the ICRP 74 and the Bert hold Lb 6411 response. The calculated values were compared with those measured and was consistency among the results. (Author)

Scientific Services Department

International Nuclear Information System (INIS)

SSD in the South Western Region employs more than 200 people, of which 90% are scientists or engineers. Their purpose is to understand and clarify the extensive technical issues which arise during the operation of many different types of plant spread over a wide area of Southern England and South Wales. Priority is given to work in terms of its potential value to the Board. This brochure illustrates some aspects of the work of SSD. Based at Regional Headquarters in Bristol, the Department undertakes 'on site' inspection followed by more thorough laboratory examinations for the diagnosis of faults, and carries out selected research activities. Most of this effort is directed towards the three nuclear sites and four large conventional power stations in the Region. (author)

People and things. CERN Courier, Jun 1989, v. 29(5)

Energy Technology Data Exchange (ETDEWEB)

Anon.

1989-06-15

The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events. The UK Institute of Physics High Energy Physics group was formed in autumn 1985 through the initiative of Brian Foster (Bristol) and Robin Devenish (Oxford) who felt that high energy physicists should play a more prominent role in the national physics community, particularly in the wake of the Ken drew report. More than fifty years after its prediction and thirty years after its discovery, still nobody knows for sure whether neutrinos have mass - only limits exist. Thus a useful addition to the literature is 'The Physics of Massive Neutrinos', by Boris Kayser, with FranQoise Gibrat- Debu and Frederic Perrier.

Designing Dialogic E-Learning in Pharmacy Professionalism Using Calibrated Feedback Loops (CFLs

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Sue Roff

2013-09-01

Full Text Available The feedback analytics of online software including Articulate and Bristol Online Surveys can be used to facilitate dialogic learning in a community of practice such as Pharmacy and, thereby, promote reflective learning by the creation of formative calibrated feedback loops. Based on work with medical, dental, nursing, osteopathic, and social work students, trainees, and registrants, the paper shows how an online learning community can be created along the continuum from undergraduate to registrant to develop authentic dialogic e-learning around standards of Professionalism. The Dundee PolyProfessionalism inventories and Situational Judgement Scenarios (SJSs can be customised for Pharmacy Professionalism learning to support evidence-based curriculum design along benchmarked learning curves and to profile Professionalism learning in individuals and cohorts.

Lipids of aquatic sediments, recent and ancient

Science.gov (United States)

Eglinton, G.; Hajibrahim, S. K.; Maxwell, J. R.; Quirke, J. M. E.; Shaw, G. J.; Volkman, J. K.; Wardroper, A. M. K.

1979-01-01

Computerized gas chromatography-mass spectrometry (GC-MS) is now an essential tool in the analysis of the complex mixtures of lipids (geolipids) encountered in aquatic sediments, both 'recent' (less than 1 million years old) and ancient. The application of MS, and particularly GC-MS, has been instrumental in the rapid development of organic geochemistry and environmental organic chemistry in recent years. The techniques used have resulted in the identification of numerous compounds of a variety of types in sediments. Most attention has been concentrated on molecules of limited size, mainly below 500 molecular mass, and of limited functionality, for examples, hydrocarbons, fatty acids and alcohols. Examples from recent studies (at Bristol) of contemporary, 'recent' and ancient sediments are presented and discussed.

Startech Hydrogen Production Final Technical Report

Energy Technology Data Exchange (ETDEWEB)

Startech Engineering Department

2007-11-27

The assigned work scope includes the modification and utilization of the Plasma Converter System, Integration of a StarCell{trademark} Multistage Ceramic Membrane System (StarCell), and testing of the integrated systems towards DOE targets for gasification and membrane separation. Testing and evaluation was performed at the Startech Engineering and Demonstration Test Center in Bristol, CT. The Objectives of the program are as follows: (1) Characterize the performance of the integrated Plasma Converter and StarCell{trademark} Systems for hydrogen production and purification from abundant and inexpensive feedstocks; (2) Compare integrated hydrogen production performance to conventional technologies and DOE benchmarks; (3) Run pressure and temperature testing to baseline StarCell's performance; and (4) Determine the effect of process contaminants on the StarCell{trademark} system.

Choosing a language in international office service encounters

DEFF Research Database (Denmark)

Hazel, Spencer

Choosing a language in international office service encounters – from multilingual miscellany to medium-of-interaction in a matter of seconds Spencer Hazel Roskilde University, Denmark In higher education settings characterized by increasing transnational student and staff mobility, members...... to a multimodal interaction analysis following the ethnomethodological tradition of Conversation Analysis. Gafaranga, J. (2000). Medium repair vs. other-language repair: Telling the medium of a bilingual conversation. International Journal of Bilingualism, 4(3), 327-350. Hall, J. K., Hellermann, J., & Pekarek...... Preisler (eds.) Language alternation, language choice and language encounter in international education. Dordrecht: Springer Preisler, Bent, Ida Klitgård, and Anne H. Fabricius. (2011). Language and learning in the international university: from English uniformity to diversity and hybridity. Bristol...

47 CFR 76.53 - Reference points.

Science.gov (United States)

2010-10-01

...″ Scottsbluff 41°51′40″ 103°39′00″ Superior 40°01′12″ 98°04′00″ Nevada: Elko 40°50′00″ 115°45′41″ Henderson 36.... Johnsbury 44°25′16″ 72°01′13″ Windsor 43°28′38″ 72°23′32″ Virginia: Bristol 36°35′48″ 82°11′04...″ Yakima 46°36′09″ 120°30′39″ West Virginia: Bluefield 37°15′29″ 81°13′20″ Charleston 38°21′01″ 81°37′52...

The deconstruction of safety arguments through adversarial counter-argument

International Nuclear Information System (INIS)

Armstrong, James M.; Paynter, Stephen E.

2007-01-01

The project Deconstructive Evaluation of Risk In Dependability Arguments and Safety Cases (DERIDASC) has recently experimented with techniques borrowed from literary theory as safety case analysis techniques [Armstrong. Danger: Derrida at work. Interdiscipl Sci Rev 2003;28(2):83-94. ; Armstrong J, Paynter S. Safe systems: construction, destruction, and deconstruction. In: Redmill F, Anderson T, editors. Proceedings of the 11th safety critical systems symposium, Bristol, UK. Berlin: Springer; 2003. p. 62-76. ISBN:1-85233-696-X. ]. This paper introduces our high-level framework for 'deconstructing' safety arguments. Our approach is quite general and should be applicable to different types of safety argumentation framework. As one example, we outline how the approach would work in the context of the Goal Structure Notation (GSN)

Camarines Sur Polytechnic Colleges Philippines An Eco-Friendly School Model

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Dr. Jose Ariel R. Ibarrientos

2015-03-01

Full Text Available Abstract Academic institutions can become more environmentally responsible through the implementation of various conservation initiative. Along this the study attempt to transform the Camarines Sur Polytechnic Colleges into living models of an ecologically sustainable learning institutions. Data was gathered from among the six administrators 336 students 62 teaching and 31 non-teaching personnel from school year 2013-2014. Questionnaire supported by interview and ocular inspection was utilized to assess the college practices along its environmental policy resource management curriculum project and budget. Results revealed that the college has an Eco Friendly Program and has implemented guidelines along solid Waste Management in Classrooms and Laboratories. Awareness on environmental policy resource management in classrooms buildings and grounds purchasing use of lights and electricity paper conservation water conservation waste management were highly implemented HI. Maintenance on air quality and waste management in the canteen were moderately implemented MI in the college. Generally the college are Aware A along environmental programs and highly implement HI its environmental practices. T-test result shows that there was no significant difference between the level of awareness and implementation on environmental practices. The proposed Eco-Friendly School Model developed by the researcher must be adopted by the college.

Educational Implication For Adopting Open-Ended Response Systems In Higher Education The Scenario Of Wa Polytechnic Ghana.

Directory of Open Access Journals (Sweden)

Nicholas A. Tetteh

2015-08-01

Full Text Available Teaching and learning is fundamentally a two-way affair the teacher transferring knowledge and the learner making meaning from the knowledge. Teaching becomes complete when the learner acquires the knowledge transferred and applies it appropriately to real life situations. However in Ghana teaching and learning has undergone a lot of alteration coupled with both negative and positive effects. In Wa Polytechnic teaching and learning has seen little or no improvement with regards to information and communication Technology ICT making it difficult for students to acquire 21st century skills and be part of the digitally connected ecosystem. Active classroom participation and engagement information sharing communication collaboration coupled with large class sizes have been a problem for teachers and students in Wa Polytechnic hence the need to conduct a study to identify productive solutions that enhance students participation and engagement in the classroom. The study investigates the role of ICT in augmenting active participation and engagement of students in the classroom via open-ended response systems. The study was conducted using Educational Design Research EDR methods. A critical analysis was done by studying the responses of the respondents which identified three forms of students classroom participation and engagement verbal classroom participation non-verbal classroom participation and after classroom teaching and learning activities. Smart phones laptop tablet iPad and regular cellular phone were the predominant devices used by students for other purpose rather than teacher-led class activities. When students were made to actively participate in the classroom using the devices as open-ended response system students engagement and their ability to contribute during lectures appreciated comparatively. It was however evident that open-ended response system was effective tool to manage large class sizes as students who were timid could

Detection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed intestinal mucosa

Directory of Open Access Journals (Sweden)

Buda A

2015-01-01

Full Text Available Andrea Buda,1,* Sonia Facchin,1,* Elisa Dassie,2 Elisabetta Casarin,3 Mark A Jepson,4 Helmut Neumann,5 Giorgia Hatem,1 Stefano Realdon,6 Renata D’Incà,1 Giacomo Carlo Sturniolo,1 Margherita Morpurgo3 1Department of Surgical, Oncological, and Gastroenterological Sciences, University of Padova, 2Department of Molecular Medicine, University of Padova, Padova, Italy; 3Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy; 4School of Biochemistry and Wolfson Bioimaging Facility, University of Bristol, Bristol, UK; 5Ludwig Demlig Endoscopic Center of Excellence, ESGE Endoscopy Training Center, University of Erlangen-Nuremberg, Erlangen, Germany; 6Veneto Institute of Oncology IOV-IRCCS, Padova, Italy *These authors contributed equally to this work Abstract: Inflammatory bowel diseases are chronic gastrointestinal pathologies causing great discomfort in both children and adults. The pathogenesis of inflammatory bowel diseases is not yet fully understood and their diagnosis and treatment are often challenging. Nanoparticle-based strategies have been tested in local drug delivery to the inflamed colon. Here, we have investigated the use of the novel avidin-nucleic acid nanoassembly (ANANAS platform as a potential diagnostic carrier in an experimental model of inflammatory bowel diseases. Fluorescent-labeled ANANAS nanoparticles were administered to mice with chemically induced chronic inflammation of the large intestine. Localization of mucosal nanoparticles was assessed in vivo by dual-band confocal laser endomicroscopy. This technique enables characterization of the mucosal microvasculature and crypt architecture at subcellular resolution. Intravascular nanoparticle distribution was observed in the inflamed mucosa but not in healthy controls, demonstrating the utility of the combination of ANANAS and confocal laser endomicroscopy for highlighting intestinal inflammatory conditions. The specific localization of

A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study.

Science.gov (United States)

Tulloh, R M R; Garratt, V; Tagney, J; Turner-Cobb, J; Marques, E; Greenwood, R; Howard, L; Gin-Sing, W; Barton, A; Ewings, P; Craggs, P; Hollingworth, W

2018-01-01

Pulmonary arterial hypertension (PAH) is an uncommon condition with progressive heart failure and premature death. Treatment costs up to £120,000 per patient per year, and the psychological burden of PAH is substantial. Mindfulness-based stress reduction (MBSR) is an intervention with the potential to reduce this burden, but to date, it has not been applied to people with pulmonary hypertension. We wished to determine whether a trial of MBSR for people with PAH would be feasible. A customised gentle MBSR programme of eight sessions was developed for people with physical disability due to PAH, and they were randomised to group-based MBSR or treatment as usual. The completeness of outcome measures including Beck Anxiety Index, Beck Depression Inventory and standard physical assessment at 3 months after randomisation were recorded. Health care utilisation was measured. Attendance at the sessions and the costs involved in delivering the intervention were assessed. Semi-structured interviews were conducted to explore the acceptability of the MBSR intervention and when appropriate the reasons for trial non-participation. Fifty-two patients were recruited, but only 34 were randomised due to patients finding it difficult to travel to sessions. Twenty-two completed all questionnaires and attended all clinics, both routine and additional in order to collect outcomes measures. The MSBR sessions were delivered in Bristol, Cardiff and London, costing, on average, between £2234 (Cardiff) and £4128 (London) per patient to deliver. Attendance at each session averaged between two patients in Bristol and Cardiff and three in London. For those receiving treatment as usual, clinician blinding was achievable. Interviews revealed that people who attended MBSR found it interesting and helpful in managing their symptoms and minimising the psychological component of their disease. We found that attendance at group MBSR was poor in people with chronic PAH within the context of a trial

Clinical response in Mexican patients with irritable bowel syndrome treated with a low diet low in fermentable carbohydrates (FODMAP).

Science.gov (United States)

Pérez y López, N; Torres-López, E; Zamarripa-Dorsey, F

2015-01-01

The low FODMAP diet eliminates carbohydrates and fermentable alcohols because they are not absorbed by the intestine, but are fermented by the microbiota, causing bloating and flatulence. To evaluate the clinical response to the low FODMAP diet in patients with the different clinical subtypes of irritable bowel syndrome (IBS). Patients attended to at the Gastroenterology Department in 2014 that were diagnosed with IBS based on the Rome III criteria were included in the study. They were managed with a low FODMAP diet for 21 days and their response to the symptoms of abdominal pain, bloating, flatulence, and stool form pre and post-diet were evaluated through the visual analogue scale, Bristol scale, and patient overall satisfaction. The results were analyzed by means, 95% CI, and the Student's t test. Of the 31 patients included in the study, 87% were women and the mean age was 46.48 years. Distribution was: IBS-C 64.5%, IBS-D 22.6%, and IBS-M 12.9%. The score for pain was 6.0 (95% CI 5.04-6.96) and the post-diet score was 2.77 (95% CI 1.60-3.95) (P<.001). The score for bloating was 7.10 (95% CI 6.13-8.06) and the post-diet score was 4.19 (95% CI 2.95-5.44) (P<.001). The score for flatulence was 5.94 (95% CI 4.79-7.08) and the post-diet score was 3.06 (IC95% 1.99-4.14) (P<.001). The pre-diet Bristol Scale result was 3.68 (95% CI 3.14-4.22) and the post-diet result was 4.10 (95% CI 3.66-4.54) (P=.1). The satisfaction percentage was 70.9%. In this first study on a Mexican population with IBS, there was significant improvement of the main symptoms, including pain, bloating, and flatulence after treatment with a low FODMAP diet. Copyright © 2015 Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. All rights reserved.

Installation of a direct fired Lanham bread baking system. A demonstration at Family Loaf Bakery Ltd. (Bristol)

Energy Technology Data Exchange (ETDEWEB)

1985-10-01

The first installation in the UK of a direct-fired continuous conveyor oven capable of producing 8,500 loaves/hour has reduced energy costs at Family Loaf Bakery's Avonmouth plant by pound 66,680/year and resulted in net cost savings to the company of pound 59,680/year. This saving was achieved by using a direct-fired oven which had a low thermal mass and small oven openings. When baking identical products, a 30% saving in oven fuel was obtained using the new system compared to conventional systems. For this bakery, it is expected to save over 12,000 GJ/year. The bread baking system was of USA development and initial teething problems adapting to the more dense UK bread have now been overcome. (U.K.).

The Rise And Fall Of The Afterlife : The 1995 Read-Tuckwell Lectures at the University of Bristol

NARCIS (Netherlands)

Bremmer, Jan N.

2002-01-01

The afterlife is still very much alive in Western civilisation, even though the truth of its existence is no longer universally accepted. Surprisingly, however, heaven, hell and the immortal soul were all ideas which arrived relatively late in the ancient world. Originally Greece and Israel - the

Environmental Sensitivity Index (ESI) Atlas: Bristol Bay, Alaska, maps and geographic information systems data (NODC Accession 0033382)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The most widely used approach to sensitive environment mapping in the United States is the NOAA Environmental Sensitivity Index (ESI). This approach systematically...

Translation and linguistic validation of the Persian version of the Bristol Female Lower Urinary Tract Symptoms instrument.

Science.gov (United States)

Pourmomeny, Abbas Ali; Rezaeian, Zahra Sadat; Soltanmohamadi, Mahsa

2017-09-01

The aim of this study was to evaluate the psychometric properties of the Persian version of the International Consultation on Incontinence Modular Questionnaire for Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) in patients with urinary tract dysfunction. After gaining permission from the International Consultation on Incontinence Modular Questionnaire (ICIQ) advisory board, the English Female Lower Urinary Tract Symptoms (FLUTS) questionnaire was translated into Persian and then translated back into English. One hundred fourteen women with pelvic floor dysfunction were asked to complete the Persian FLUTS and International Consultation on Incontinence Modular Questionnaire Overactive Bladder Questionnaire (ICIQ-OAB). The Persian FLUTS questionnaire was also readministered to 20 patients 2 weeks after their initial visit. Study data were analyzed using SPSS V16.0. To validate the translated questionnaire, we assayed content/face validity, internal consistency/reliability, and construct validity. Internal consistency and test-retest reliability were assessed using Cronbach's alpha and the intraclass correlation coefficient (ICC) respectively. The mean age of the patients was 48.8 years old, 84% were married, and 59% had at least one Caesarean. Except for very few missing data, there is no any ambiguity in the Persian version of the FLUTS questionnaire. The Cronbach's alpha was 0.83, indicating a high internal consistency. Concerning criterion validity, correlation between the Persian FLUTS and the OAB was 0.77 (p Persian version of the FLUTS questionnaire demonstrates good internal consistency, content validity, and reliability.

Nuclear engineering in the National Polytechnic Institute

International Nuclear Information System (INIS)

Del Valle G, E.

2008-12-01

In the National Polytechnic Institute the bachelor degree in physics and mathematics, consists of 48 subjects in the common trunk. For the nuclear engineering option, from the fifth semester undergoing 9 specific areas within the Nuclear Engineering Department : introduction to nuclear engineering, power cycles thermodynamics, heat transfer, two courses of nuclear reactors theory, two of nuclear engineering, one course of laboratory and other of radiation protection. There is also a master in nuclear engineering aims train human resources in the area of power and research nuclear reactors to meet the needs of the nuclear industry in Mexico, as well as train highly qualified personnel in branches where are used equipment involving radiation and radioisotopes tale as Medicine, Agriculture and Industry. Among its compulsory subjects are: radiation interaction with the matter, measurements laboratory, reactor physics I and II, reactor engineering, reactor laboratory and thesis seminar. Optional, are: engineering of the radiation protection, computers in the nuclear engineering, nuclear systems dynamics, power plants safety, flow in two phases, reliability and risk analysis, nuclear power systems design, neutron transport theory. Many graduates of this degree have been and are involved in various phases of the nuclear project of Laguna Verde. The Nuclear Engineering Department has a subcritical nuclear reactor of light water and natural uranium and one isotopic source of Pu-Be neutrons of 5 Ci. It also has a multichannel analyzers, calibrated sources of alpha, beta and gamma radiation, a gamma spectrometer of high resolution and low background, a specialized library and one data processing center. In relation particularly to radiation protection, it is clear that there is a lack of specialists, as reflected in radiological control problems in areas such as medicine and industry. Given this situation, it is perceived to be required post-graduate studies at Master and Ph

Assessing the sensitivity of images in research collections: A new approach at the Wellcome Library.

Science.gov (United States)

Wakely, Helen; Dakin, Carly

2015-06-01

In 2014 The Wellcome Library, part of the Wellcome Trust, introduced a new policy in order to address research access to personal data within its collections. The policy has now been used by library staff for almost a year. The policy was devised using a multi-stage approach which consisted of internal surveys and 1:1 interviews. Library staff can use the policy to guide decisions based on what level of access to award material donated or contributed to the Wellcome collections. The policy has been applied to 1 - a series of victorian medical photographs supplied by University Hospitals Bristol NHS Foundation Trust, and 2 - an album of family photographs from the collection of the psychiatrist Dr Ann Dally. Following almost a year in circulation the advantages and disadvantages can now be summarised.

People and things. CERN Courier, Jun 1989, v. 29(5)

International Nuclear Information System (INIS)

Anon.

1989-01-01

The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events. The UK Institute of Physics High Energy Physics group was formed in autumn 1985 through the initiative of Brian Foster (Bristol) and Robin Devenish (Oxford) who felt that high energy physicists should play a more prominent role in the national physics community, particularly in the wake of the Ken drew report. More than fifty years after its prediction and thirty years after its discovery, still nobody knows for sure whether neutrinos have mass - only limits exist. Thus a useful addition to the literature is 'The Physics of Massive Neutrinos', by Boris Kayser, with FranQoise Gibrat- Debu and Frederic Perrier

First report of Trichinella pseudospiralis in a red fox in mainland Britain.

Science.gov (United States)

Learmount, Jane; Boughtflower, Valerie; Allanson, Peter C; Hartley, Kayleigh M; Gutierrez, Alba Barrecheguren; Stephens, Nathalie A; Marucci, Gianluca; Smith, Graham C

2015-03-15

Active surveillance of red foxes for Trichinella has been undertaken in mainland Britain since 1999. Post-mortems are carried out, followed by a magnetic stirrer method for sample digestion based on European Commission (EC) Regulation 216/2014 (which amends 2075/2005). Initially samples are tested in batches of 20 foxes and in December 2013, for the first time under the surveillance programme, a batch tested positive for Trichinella at the Animal and Plant Health Agency, York. Further individual tests identified one infected fox, from the Bristol area. The larvae were identified as Trichinella pseudospiralis. This is the first report of T. pseudospiralis in Great Britain and suggests the possibility of a cycle of infection existing in wildlife. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

Molecular relationships between closely related strains and species of nematodes

Science.gov (United States)

Butler, M. H.; Wall, S. M.; Luehrsen, K. R.; Fox, G. E.; Hecht, R. M.

1981-01-01

Electrophoretic comparisons have been made for 24 enzymes in the Bergerac and Bristol strains of Caenorhabditis elegans and the related species, Caenorhabditis briggsae. No variation was detected between the two strains of C. elegans. In contrast, the two species, C. elegans and C. briggsae exhibited electrophoretic differences in 22 of 24 enzymes. A consensus 5S rRNA sequence was determined for C. elegans and found to be identical to that from C. briggsae. By analogy with other species with relatively well established fossil records it can be inferred that the time of divergence between the two nematode species is probably in the tens of millions of years. The limited anatomical evolution during a time period in which proteins undergo extensive changes supports the hypothesis that anatomical evolution is not dependent on overall protein changes.

Public health assessment for public health implications of radiation contamination at former clock factories located in Bristo (Hartford County), New Haven, (New Haven County), Thomaston (Litchfield County), and Waterbury (New Haven County), Connecticut, Region 1. Final report

International Nuclear Information System (INIS)

1999-01-01

This public health assessment was developed (1) to evaluate the radiation data collected by the Connecticut Department of Environmental Protection (CT DEP) at structures that once housed clock factories in four Connecticut municipalities, and (2) to determine whether a public health hazard exists at any of these sites from the contamination. Contamination was detected at levels that may pose a health risk to current occupants at the former Waterbury Clock Factory, the former Lux Clock Factory, and the former Benrus Clock Company buildings in Waterbury; the former Sessions Clock Company in Bristol; and the former Seth Thomas Clock Company in Thomaston. However, none of the radiation levels detected pose an immediate health problem. The Connecticut Department of Public Health recommends that individuals be disassociated from areas with radiation at levels exceeding 15 mRem/year

Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

DEFF Research Database (Denmark)

Eggermont, Alexander M M; Chiarion-Sileni, Vanna; Grob, Jean-Jacques

2015-01-01

was stratified by disease stage and geographical region. The primary endpoint was recurrence-free survival, assessed by an independent review committee, and analysed by intention to treat. Enrollment is complete but the study is ongoing for follow-up for analysis of secondary endpoints. This trial is registered...... with EudraCT, number 2007-001974-10, and ClinicalTrials.gov, number NCT00636168. FINDINGS: Between July 10, 2008, and Aug 1, 2011, 951 patients were randomly assigned to ipilimumab (n=475) or placebo (n=476), all of whom were included in the intention-to-treat analyses. At a median follow-up of 2·74 years...... at this dose and schedule requires additional assessment based on distant metastasis-free survival and overall survival endpoints to define its definitive value. FUNDING: Bristol-Myers Squibb....

UNderstanding uptake of Immunisations in TravellIng aNd Gypsy communities (UNITING): a qualitative interview study.

Science.gov (United States)

Jackson, Cath; Dyson, Lisa; Bedford, Helen; Cheater, Francine M; Condon, Louise; Crocker, Annie; Emslie, Carol; Ireland, Lana; Kemsley, Philippa; Kerr, Susan; Lewis, Helen J; Mytton, Julie; Overend, Karen; Redsell, Sarah; Richardson, Zoe; Shepherd, Christine; Smith, Lesley

2016-09-01

Gypsies, Travellers and Roma (referred to as Travellers) are less likely to access health services, including immunisation. To improve immunisation rates, we need to understand what helps and hinders individuals in these communities in taking up immunisations. (1) Investigate the barriers to and facilitators of acceptability and uptake of immunisations among six Traveller communities across four UK cities; and (2) identify possible interventions to increase uptake of immunisations in these Traveller communities that could be tested in a subsequent feasibility study. Three-phase qualitative study underpinned by the social ecological model. Phase 1: interviews with 174 Travellers from six communities: Romanian Roma (Bristol); English Gypsy/Irish Traveller (Bristol); English Gypsy (York); Romanian/Slovakian Roma (Glasgow); Scottish Showpeople (Glasgow); and Irish Traveller (London). Focus on childhood and adult vaccines. Phase 2: interviews with 39 service providers. Data were analysed using the framework approach. Interventions were identified using a modified intervention mapping approach. Phase 3: 51 Travellers and 25 service providers attended workshops and produced a prioritised list of potentially acceptable and feasible interventions. There were many common accounts of barriers and facilitators across communities, particularly across the English-speaking communities. Scottish Showpeople were the most similar to the general population. Roma communities experienced additional barriers of language and being in a new country. Men, women and service providers described similar barriers and facilitators. There was widespread acceptance of childhood and adult immunisation, with current parents perceived as more positive than their elders. A minority of English-speaking Travellers worried about multiple/combined childhood vaccines, adult flu and whooping cough. Cultural concerns about vaccines offered during pregnancy and about human papillomavirus were most evident in

FROM THE POLYTECHNIC INSTITUTE TO THE CONSTRUCTION ACADEMY

Directory of Open Access Journals (Sweden)

BOLSHAKOV V. I.

2016-01-01

Full Text Available Formulation of the problem. Developed construction industry is the basis of prosperity of the country as a whole and particular city in particular. An important role in the training of young builders relies on the training institutions, which, even replacing each other on the city map, retain and develop the traditions of engineering and construction education. The knowledge of the history of the first technical institution of building structure in our city will significantly influence the formation of civic and patriotic position of young engineers of building industry. Analysis of the research. Тhe history of higher polytechnic education in Ukraine of the first quarter of the twentieth century rather thoroughly was investigated in the works of V. Onopriyenko, V. Tarasov, A. Woroch, C. Choir, S. Hovrych, I. Fedosova and others. Specifically I. Fedosova considered features of formation of student contingent in the technical universities in the period which is considered and analyzed the source and status of research of the history of higher technical education in Ukraine. The formation of higher technical education in Katerynoslav was considered in the works of G. Shvyd’ko, V. Starostin, V. Savchuk, A. Bystryakov and V. Bolshakov. The purpose of the article is analysis of the development of higher building and architectural education in Katerynoslav (Dnipropetrovsk during the XX - XXI century. Conclusion. The tradition of training of highly qualified engineering and architecture specialist in the city has already a hundred years, and Prydniprovs’ka State Academy of Civil Engineering and Architecture concentrating all the achievements of its predecessors, absorbed throughout history research and development of talented architects, builders and engineers of the construction industry of the city, confidently looks into the future.

Projecting the Water and Electric Consumption of Polytechnic University of the Philippines

Science.gov (United States)

Urrutia, Jackie D.; Mercado, Joseph; Bautista, Lincoln A.; Baccay, Edcon B.

2017-03-01

This study investigates water and electric consumption in Polytechnic University of the Philippines - Sta. Mesa using a time series analysis. The researchers analyzed the water and electric usage separately. Electric consumption was examined in terms of pesos and kilowatt-hour, while water consumption was analyzed in pesos and cubic meter. The data are gathered from the university limited only from January 2009 to July 2015 in a monthly based record. The aim is to forecast the water and electric usage of the university for the years 2016 and 2017. There are two main statistical treatments that the researchers conducted to be able to formulate mathematical models that can estimate the water and electric consumption of the said school. Using Seasonal Autoregressive Integrated Moving Average (SARIMA), electric usage was forecasted in peso and kilowatt-hour, and water usage in peso and cubic meter. Moreover, the predicted values of the consumptions are compared to the actual values using Paired T-test to examine whether there is a significant difference. Forecasting accurately the water and electric consumption would be helpful to manage the budget allotted for the water and electric consumption of PUP - Sta. Mesa for the next two years.

Integration of learning technologies into teaching within Fijian Polytechnic Institutions

Directory of Open Access Journals (Sweden)

Shalendra Kumar

2016-11-01

Full Text Available Abstract In the 21st century, learning technologies have increasingly become pervasive within various forms of learning environments. Institutions of higher education are increasingly turning to these technologies to resource and support their teaching and learning environments under distributed circumstances, face-to-face or blended. Recently, the Fijian Ministry of Education systematically introduced learning technologies into Fiji’s technical colleges to support teaching and learning. However, prior to the widespread deployment of these technologies, little information was available on educators’ perception of the value of these technologies, and the extent to which this could influence adoption. The purpose of this study was to gain a better understanding of lecturers’ perceptions of the value of learning technologies and factors likely to influence their decisions to adopt and integrate these technologies into teaching as well as challenges they are likely to face. A survey was administered to fifty five self-selected lecturers involved in teaching within three Polytechnics in Fiji. Although overall findings suggested that lecturers strongly valued the contribution of learning technologies in enhancing student learning, a number of factors likely to influence the rapid adoption of these technologies were identified. These included attitude towards technology and perceived usefulness of technology in teaching, the institutional cultural environment, as well as resources available to support uptake. This research contributes to the growing significance of individual, contextual and cultural influences in the adoption of learning technologies into teaching.

Communication campaign for the selecting of a technical undergraduate degree at the Salesian Polytechnic University

Directory of Open Access Journals (Sweden)

Adriana Priscila Vallejo

2016-08-01

Full Text Available This paper aims to make available to the scientific community, a communication campaign designed based on the factors involved in choosing a technical undergraduate degree at the Salesian Polytechnic University in Cuenca. Given the momentum that currently provided by the Ecuadorean government to technical and technological country institutes, must take measures to encourage the academic preparation of students opting not only for technical training but by engineering which ensures professionals that guarantee the rights stipulated in the Constitution of Ecuador and help boost the economy with innovation, research and entrepreneurship. The research is qualitative. It is based on focus groups and semi-structured interviews; its conceptual basis is defined by marketing approaches and public relations services; which means that the above factors constitute the main element for the development of a creative communicational approach to provide a more valuable study fields of the institution. 

Comparison of the eLearning Solution at MUAF in Brno and Polytechnic University in Madrid

Directory of Open Access Journals (Sweden)

Tomáš Foltýnek

2006-01-01

Full Text Available The necessity of eLearning support of the university studies is setting up (or was setting up at the universities all over the world. This paper compares the eLearning technologies available at Mendel University in Brno (MUAF, Czech Republic, and Polytechnic University in Madrid (UPM, Spain, in the context of different conditions at both universities. The level of using of these technologies and practical experiences with them are evaluated too. In concrete this paper deals with the systems GATE (GAbinete de TeleEducación and AulaWeb, used at the UPM and system ELIS, used at MUAF. The fifteen-year experiences with development of eLearning at UPM are very valuable study material for the developers of the ELIS system. Some, especially conception properties of the ELIS system, can be, on the other hand, useful for inspiration vice versa.

Education and training at the Rensselaer Polytechnic Institute reactor critical facility

International Nuclear Information System (INIS)

Harris, D.R.

1989-01-01

The Rensselaer Polytechnic Institute (RPI) Reactor Critical Facility (RCF) has provided hands-on education and training for RPI and other students for almost a quarter of a century. The RCF was built in the 1950s by the American Locomotive Company (ALCO) as a critical facility in which to carry out experiments in support of the Army Package power Reactor (APPR) program. A number of APPRs were built and operated. In the middle 1960s, ALCO went out of business and provided the facility to RPI. Since that time, RPI has operated the RCF primarily in a teaching mode in the nuclear engineering department, although limited amounts of reactor research, activation analysis, and reactivity assays have been carried out as well. Recently, a U.S. Department of Energy (DOE) upgrade program supported refueling the RCF with 4.81 wt% enriched UO 2 high-density pellets clad in stainless steel rods. The use of these SPERT (F1) fuel rods in the RCF provided a cost-effective approach to conversion from high-enrichment bombgrade fuel to low-enrichment fuel. More important, however, is the fact that the new fuel is of current interest for light water power reactors with extended lifetime fuel. Thus, not only are critical reactor experiments being carried out on the fuel but, more importantly, the quality of the education and training has been enhanced

The impact of melt ponds on summertime microwave brightness temperatures and sea-ice concentrations

DEFF Research Database (Denmark)

Kern, Stefan; Rösel, Anja; Pedersen, Leif Toudal

2016-01-01

% sea-ice concentration. None of the algorithms investigated performs best based on our investigation of data from summer 2009. We suggest that those algorithms which are more sensitive to melt ponds could be optimized more easily because the influence of unknown snow and sea-ice surface property...... of eight sea-ice concentration retrieval algorithms to melt ponds by comparing sea-ice concentration with the melt-pond fraction. We derive gridded daily sea-ice concentrations from microwave brightness temperatures of summer 2009. We derive the daily fraction of melt ponds, open water between ice floes......, and the ice-surface fraction from contemporary Moderate Resolution Spectroradiometer (MODIS) reflectance data. We only use grid cells where the MODIS sea ice concentration, which is the melt-pond fraction plus the ice-surface fraction, exceeds 90 %. For one group of algorithms, e.g., Bristol and Comiso...

Simulation of the fate of faecal bacteria in estuarine and coastal waters based on a fractionated sediment transport model

Science.gov (United States)

Yang, Chen; Liu, Ying

2017-08-01

A two-dimensional depth-integrated numerical model is refined in this paper to simulate the hydrodynamics, graded sediment transport process and the fate of faecal bacteria in estuarine and coastal waters. The sediment mixture is divided into several fractions according to the grain size. A bed evolution model is adopted to simulate the processes of the bed elevation change and sediment grain size sorting. The faecal bacteria transport equation includes enhanced source and sink terms to represent bacterial kinetic transformation and disappearance or reappearance due to sediment deposition or re-suspension. A novel partition ratio and dynamic decay rates of faecal bacteria are adopted in the numerical model. The model has been applied to the turbid water environment in the Bristol Channel and Severn estuary, UK. The predictions by the present model are compared with field data and those by non-fractionated model.

An analysis of the changes in ability and knowledge of students taking A-level physics and mathematics over a 35 year period

Science.gov (United States)

Barham, Peter J.

2012-03-01

New undergraduate students arriving to study physics at the University of Bristol from 1975 onwards have all taken the same test of their knowledge and understanding of physics and mathematics. Many of the questions test knowledge of material that has been in the A-level syllabus for maths or physics throughout this period. The ability of incoming students to answer these questions declined significantly in the 1990s with average scores falling from around 75% up to 1990 to below 50% after 2000 against a background of increasing A-level grades of the entrants to the programme. It is suggested that changes in teaching and examination methods have caused students to be less able to carry out multi-stage calculations and that the introduction of modular examinations may have encouraged a culture where students tend to forget material learnt in previous modules.

Northern part, Ten Mile and Taunton River basins

Science.gov (United States)

Williams, John R.; Willey, Richard E.

1967-01-01

The northern part of the Ten Mile and Taunton River basins is an area of about 195 square miles within Norfolk, Plymouth, and Bristol Counties in southeastern Massachusetts. The northern boundary of the area (plate 1) is the drainage divide separating these basins from that of the Charles, Neponset, and Weymouth River basins. The western boundary is, for the most part, the divide separating the basins from the Blackstone River basin. The eastern boundary is at the edge of the Brockton-Pembroke area (Petersen, 1962; Petersen and Shaw, 1961). The southern boundary in Seekonk is the northern limit of the East Providence quadrangle, for which a ground-water map was prepared by Allen and Gorman (1959); eastward, the southern boundaries of the city of Attleboro and the towns of Norton, Easton, and West Bridgewater form the southern boundary of the area.

Aerobic treatment of swine manure to enhance anaerobic digestion and microalgal cultivation.

Science.gov (United States)

Bekoe, Dominic; Wang, Lijun; Zhang, Bo; Scott Todd, Matthew; Shahbazi, Abolghasem

2018-02-01

Aerobic treatment of swine manure was coupled with anaerobic digestion and microalgal cultivation. A 14-day aerobic treatment reduced the total solid content of swine manure by >15%. Ammonia and carbon dioxide were stripped by the air supplied, and this off-gas was further used to aerate the culture of Chlorella vulgaris. The microalgal growth rates in Bristol medium and the wastewater with the off-gas increased from 0.08 to 0.22 g/L/d and from 0.15 to 0.24 g/L/d, respectively. Meanwhile, the aerobically treated swine manure showed a higher methane yield during anaerobic digestion. The experimental results were used to establish a demonstration unit consisting of a 100 L composter, a 200 L anaerobic digester, a 60 L tubular photobioreactor, and a 300 L micro-open raceway pond.

77 FR 14011 - Assessment of Potential Large-Scale Mining on the Bristol Bay Watershed of Alaska: Nomination of...

Science.gov (United States)

2012-03-08

... affect wildlife and human populations in the region. Additional information describing the assessment...) ecotoxicology, (8) wildlife ecology, and/or (9) indigenous Alaskan cultures. Selection Criteria: Selection...) absence of financial conflicts of interest; (5) no actual conflicts of interest or the appearance of bias...

77 FR 11111 - Assessment of Potential Large-Scale Mining on the Bristol Bay Watershed of Alaska: Nomination of...

Science.gov (United States)

2012-02-24

... effects are likely to affect wildlife and human populations in the region. Additional information..., (6) seismology, (7) ecotoxicology, (8) wildlife ecology, and/or (9) indigenous Alaskan cultures... committee setting; (4) absence of financial conflicts of interest; (5) no actual conflicts of interest or...

77 FR 33213 - An Assessment of Potential Mining Impacts on Salmon Ecosystems of Bristol Bay, Alaska-Peer Review...

Science.gov (United States)

2012-06-05

...--Expertise in indigenous Alaskan cultures. Dr. Dennis Dauble, Washington State University--Expertise in... current practices? (4) Are the potential risks to salmonid fish due to habitat loss and modification and... characterize risks to wildlife and human cultures due to risks to fish? If not, what suggestions do you have...

Needles, Jabs and Jags: a qualitative exploration of barriers and facilitators to child and adult immunisation uptake among Gypsies, Travellers and Roma

Directory of Open Access Journals (Sweden)

Cath Jackson

2017-03-01

Full Text Available Abstract Background Gypsies, Travellers and Roma (referred to as Travellers are less likely to access health services including immunisation. To improve immunisation rates, it is necessary to understand what helps and hinders individuals in these communities in taking up immunisations. This study had two aims. 1. Investigate the views of Travellers in the UK on the barriers and facilitators to acceptability and uptake of immunisations and explore their ideas for improving immunisation uptake; 2. Examine whether and how these responses vary across and within communities, and for different vaccines (childhood and adult. Methods This was a qualitative, cross-sectional interview study informed by the Social Ecological Model. Semi-structured interviews were conducted with 174 Travellers from six communities: Romanian Roma, English Gypsy/Irish Travellers (Bristol, English Gypsy (York, Romanian/Slovakian Roma, Scottish Show people (Glasgow and Irish Traveller (London. The focus was childhood and selected adult vaccines. Data were analysed using the Framework approach. Results Common accounts of barriers and facilitators were identified across all six Traveller communities, similar to those documented for the general population. All Roma communities experienced additional barriers of language and being in a new country. Men and women described similar barriers and facilitators although women spoke more of discrimination and low literacy. There was broad acceptance of childhood and adult immunisation across and within communities, with current parents perceived as more positive than their elders. A minority of English-speaking Travellers worried about multiple/combined childhood vaccines, adult flu and whooping cough and described barriers to booking and attending immunisation. Cultural concerns about antenatal vaccines and HPV vaccination were most evident in the Bristol English Gypsy/Irish Traveller community. Language, literacy, discrimination, poor

Partially hydrolyzed guar gum in pediatric functional abdominal pain.

Science.gov (United States)

Romano, Claudio; Comito, Donatella; Famiani, Annalisa; Calamarà, Sabrina; Loddo, Italia

2013-01-14

To assess the effects of partially hydrolyzed guar gum (PHGG) diet supplement in pediatric chronic abdominal pain (CAP) and irritable bowel syndrome (IBS). A randomized, double-blind pilot study was performed in sixty children (8-16 years) with functional bowel disorders, such as CAP or IBS, diagnosed according to Rome III criteria. All patients underwent ultrasound, blood and stool examinations to rule out any organic disease. Patients were allocated to receive PHGG at dosage of 5 g/d (n = 30) or placebo (fruit-juice n = 30) for 4 wk. The evaluation of the efficacy of fiber supplement included IBS symptom severity score (Birmingham IBS Questionnaire), severity of abdominal pain (Wong-Baker Face Pain Rating Score) and bowel habit (Bristol Stool Scale). Symptom scores were completed at 2, 4, and 8 wk. The change from baseline in the symptom severity scale at the end of treatment and at 4 wk follow-up after treatment was the primary endpoint. The secondary endpoint was to evaluate compliance to supplementation with the PHGG in the pediatric population. Differences within groups during the treatment period and follow-up were evaluated by the Wilcoxon signed-rank test. The results of the study were assessed considering some variables, such as frequency and intensity of symptoms with modifications of the bowel habit. Both groups were balanced for baseline characteristics and all patients completed the study. Group A (PHGG group) presented a higher level of efficacy compared to group B (control group), (43% vs 5%, P = 0.025) in reducing clinical symptoms with modification of Birmingham IBS score (median 0 ± 1 vs 4 ± 1, P = 0.025), in intensity of CAP assessed with the Wong-Baker Face Pain Rating Score and in normalization of bowel habit evaluated with the Bristol Stool Scale (40% vs 13.3%, P = 0.025). In IBS subgroups, statistical analysis shown a tendency toward normalization of bowel movements, but there was no difference in the prevalence of improvement in two bowel

Strategies for the management and prevention of conformation-related respiratory disorders in brachycephalic dogs

Directory of Open Access Journals (Sweden)

Packer RMA

2015-06-01

Full Text Available Rowena MA Packer,1 Michael S Tivers2 1Department of Clinical Science and Services, Royal Veterinary College, University of London, London, 2School of Veterinary Sciences, University of Bristol, Bristol, UK Abstract: Brachycephalic (short-muzzled dogs are increasingly popular pets worldwide, with marked increases in registrations of breeds such as the Pug and French Bulldog over the past decade in the UK. Despite their popularity, many brachycephalic breeds are affected by an early-onset, lifelong respiratory disorder, brachycephalic obstructive airway syndrome (BOAS. This disorder arises due to a mismatch in the proportions of the skull and the soft tissues held within the nose and pharynx, resulting in obstruction of the airway during respiration. Increased airway resistance encourages secondary changes such as eversion of the laryngeal saccules and collapse of the larynx. Clinical signs of BOAS are often early onset and chronic, including dyspnea, exercise intolerance, heat intolerance, and abnormal and increased respiratory noise. Episodes of severe dyspnea can also occur, leading to cyanosis, syncope, and death. BOAS may have a severe impact upon the welfare of affected dogs, compromising their ability to exercise, play, eat, and sleep. Although a well-described condition, with surgical treatments for the palliation of this disorder published since the 1920s, many dogs still experience airway restrictions postsurgically and a compromised quality of life. In addition, the prevalence of this disorder does not appear to have substantially reduced in this time, and may have increased. Ultimately, strategies to improve the breeding of these dogs to prevent BOAS are required to improve brachycephalic health and welfare. Recent studies have revealed conformational risk factors associated with BOAS, such as short muzzles and thick necks, which should be discouraged to avoid perpetuating this serious disorder. Positive changes to brachycephalic

Electroacupuncture for patients with diarrhea-predominant irritable bowel syndrome or functional diarrhea: A randomized controlled trial.

Science.gov (United States)

Zheng, Hui; Li, Ying; Zhang, Wei; Zeng, Fang; Zhou, Si-Yuan; Zheng, Hua-Bin; Zhu, Wen-Zeng; Jing, Xiang-Hong; Rong, Pei-Jing; Tang, Chun-Zhi; Wang, Fu-Chun; Liu, Zhi-Bin; Wang, Shi-Jun; Zhou, Mei-Qi; Liu, Zhi-Shun; Zhu, Bing

2016-06-01

Diarrhea-predominant irritable bowel syndrome (IBS-D) and functional diarrhea (FD) are highly prevalent, and the effectiveness of acupuncture for managing IBS-D and FD is still unknown.The aim of this study was to compare the effectiveness of electroacupuncture with loperamide.It was a prospective, randomized, parallel group controlled trial.A total of 448 participants were randomly assigned to He electroacupuncture group (n = 113), Shu-Mu electroacupuncture group (n = 111), He-Shu-Mu electroacupuncture group (n = 112), or loperamide group (n = 112). Participants in the 3 acupuncture groups received 16 sessions of electroacupuncture during a 4-week treatment phase, whereas participants in the loperamide group received oral loperamide 2 mg thrice daily. The primary outcome was the change from baseline in stool frequency at the end of the 4-weeks treatment. The secondary outcomes were the Bristol scale, the MOS 36-item short form health survey (SF-36), the weekly average number of days with normal defecations and the proportion of adverse events.Stool frequency was significantly reduced at the end of the 4-week treatment in the 4 groups (mean change from baseline, 5.35 times/week). No significant difference was found between the 3 electroacupuncture groups and the loperamide group in the primary outcome (He vs. loperamide group [mean difference 0.6, 95% CI, -1.2 to 2.4]; Shu-Mu vs. loperamide group [0.4, 95% CI, -1.4 to 2.3]; He-Shu-Mu vs. loperamide group [0.0, 95% CI, -1.8 to 1.8]). Both electroacupuncture and loperamide significantly improved the mean score of Bristol scale and increased the weekly average number of days with normal defecations and the mean scores of SF-36; they were equivalent in these outcomes. However, the participants in electroacupuncture groups did not report fewer adverse events than those in the loperamide group. Similar results were found in a subgroup analysis of separating patients with IBS-D and FD patients.Electroacupuncture is

Design of SGLT2 Inhibitors for the Treatment of Type 2 Diabetes: A History Driven by Biology to Chemistry.

Science.gov (United States)

Cai, Wenqing; Jiang, Linlin; Xie, Yafei; Liu, Yuqiang; Liu, Wei; Zhao, Guilong

2015-01-01

A brief history of the design of sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors is reviewed. The design of O-glucoside SGLT2 inhibitors by structural modification of phlorizin, a naturally occurring O-glucoside, in the early stage was a process mainly driven by biology with anticipation of improving SGLT2/SGLT1 selectivity and increasing metabolic stability. Discovery of dapagliflozin, a pioneering C-glucoside SGLT2 inhibitor developed by Bristol-Myers Squibb, represents an important milestone in this history. In the second stage, the design of C-glycoside SGLT2 inhibitors by modifications of the aglycone and glucose moiety of dapagliflozin, an original structural template for almost all C-glycoside SGLT2 inhibitors, was mainly driven by synthetic organic chemistry due to the challenge of designing dapagliflozin derivatives that are patentable, biologically active and synthetically accessible. Structure-activity relationships (SAR) of the SGLT2 inhibitors are also discussed.

Calibration of Nuclear Track Detectors

International Nuclear Information System (INIS)

Vukovic, J.B; Antanasijevic, R.; Novakovic, V.; Tasic, M.

1998-01-01

In this work we compare some of our preliminary results relating to the calibration Nuclear Track Detectors (NTD) with corresponding results obtained from other participants at the First International Intercomparison of Image Analyzers (III 97/98). Thirteen laboratories from Algeria, China, Czech Rep., France. Germany, Greece, Hungary, India, Italy, Mexico, Saudi Arabia, Slovenia and Yugoslavia participated in the III A 97/98. The NTD was 'Tustrack', Bristol. This type of CR-39 detector was etched by the organizer (J.Paltarey of al, Atomic Energy Research Institute, HPD, Budapest, Hungary). Etching condition was: 6N NaOH, 70 0C . Seven series detectors were exposed with the sources: B(n,a)Li, Am-241, Pu-Be(n,p), Radon and Am-Cm-Pu. Following parameters of exposed detectors were measured: track density of different sorts of tracks (circular, elliptical, track overlapping, their diameters, major and minor axis and other). (authors)

Application of solid state nuclear track detectors to measurements of natural alpha-radioactivity in human body tissues

International Nuclear Information System (INIS)

Henshaw, D.L.

1989-01-01

A review of the work at Bristol University on the determination of α-activity in human tissues is given. Techniques for the quantitative analysis of α-activity in CR-39 (TASTRAK) plastic are summarized. The distribution of α-activity in lung, bone, bone marrow and teeth is described together with the typical activity and dose values. Special emphasis is given to the α-radiation dose to red bone marrow and to the foetus. The contribution from radon to the dose received by these tissues is addressed. It is concluded that the dose from internal α-emitters is often comparable to that from low LET radiations at around 1 mSv yr -1 . In cases of high radon exposure, >400 Bq m -3 or above, the cost contribution from radon to the red bone marrow and the foetus is likely to be significantly in excess of 1 mSv yr -1 . (author)

A Gentleman's mad-doctor in Georgian England: Edward Long Fox and Brislington House.

Science.gov (United States)

Smith, Leonard

2008-06-01

The late eighteenth and early nineteenth centuries were a period of particular innovation in the history of British psychiatry. Enlightenment ideas brought a change in attitudes to insanity, reflected in the growing prevalence of psychologically based treatment techniques being implemented in both public and private institutions. A new group of practitioners, specializing in the treatment and management of insanity, was emerging. One of the most prominent and successful was Dr. Edward Long Fox, a Bristol physician. His main venture was the establishment of Brislington House in 1806. Here he created a state-of-the-art asylum, catering mainly for the wealthier members of society. Its unique design, with seven distinct houses, enabled classification of patients according to social class as well as behavioural presentation. Within a context of safety and security, Fox sought to provide a therapeutic regime based on the principles and practices of moral management.

Uma auditoria confiável adiciona valor?

Directory of Open Access Journals (Sweden)

Ricardo D. Brito

2006-01-01

Full Text Available Este artigo estuda o impacto das falhas de auditorias sobre os preços das ações dos clientes dos auditores. Examinamos especificamente o impacto no valor de mercado dos clientes das 5 Grandes, cobrindo eventos de 2002 nos quais os procedimentos de auditoria de uma delas e sua independência encontravam-se sob escrutínio: Omnicon, Merck, WorldCom, Qwest, Xerox, Bristol Meyers, Duke Energy, El Paso e AOL. Em geral, nas falhas envolvendo a Arthur Andersen, seus clientes e os clientes da auditoria responsável à época do reconhecimento da falha experimentaram reações de mercado estatisticamente negativas. Em eventos envolvendo as outras 4 Grandes, os clientes não experimentaram reações estatisticamente negativas. A ordem da SEC para certificação dos Diretores-Presidentes (CEO causa volatilidade mas não reações estatisticamente negativas.

An analysis of personnel dose records which justifies the application of cost-benefit analysis techniques in the design of an afterloading facility and the use of controlled areas and systems of work within suite to control occupational exposure

Energy Technology Data Exchange (ETDEWEB)

Gifford, D; Kear, D [Bristol General Hospital (UK); Godden, T J [Bristol Radiotherapy and Oncology Centre (UK)

1990-03-01

The sealed source operational policies employed at the Bristol Radiotherapy and Oncology Centre are reviewed. On the basis of the cost-benefit analysis, it was decided not to provide additional shielding but rather to introduce administrative controls based on local rules which contained systems of work and the operational policies for the afterloading systems. After using the MDR afterloading systems for 2 years, a period in which there has also been a marked increase in interstitial brachytherapy, an analysis was made of the doses received by nursing staff over the past 8 years. This has shown that, in spite of higher dose rates in the corridor areas because of the use of an MDR system and the increase in interstitial techniques, the doses to ward nurses have been significantly reduced by encouraging staff to comply with the ALARA principle and the introduction of afterloading systems. (author).

Food shopping habits, physical activity and health-related indicators among adults aged ≥70 years.

Science.gov (United States)

Thompson, Janice L; Bentley, Georgina; Davis, Mark; Coulson, Jo; Stathi, Afroditi; Fox, Kenneth R

2011-09-01

To investigate the food shopping habits of older adults in the UK and explore their potential associations with selected health-related indicators. A cross-sectional study including objectively measured physical activity levels, BMI, physical function and self-reported health status and dietary intake. Bristol, UK. A total of 240 older adults aged ≥70 years living independently. Mean age was 78·1 (sd 5·7) years; 66·7 % were overweight or obese and 4 % were underweight. Most (80·0 %) carried out their own food shopping; 53·3 % shopped at least once weekly. Women were more likely to shop alone (P driven (P car at least once weekly at large supermarket chains, with most finding high-quality fruit, vegetables and low-fat products easily accessible. Higher levels of physical function and physical activity and better self-reported health are important in supporting food shopping and maintaining independence.

Soil Survey Geographic (SSURGO) Soil Polygons for the State of Rhode Island: Bristol, Kent, Newport, Providence, and Washington Counties

Data.gov (United States)

University of Rhode Island Geospatial Extension Program — 2013 VERSION 6 Spatial: This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative...

76 FR 33310 - Bristol-Myers Squibb Co. et al.; Withdrawal of Approval of 70 New Drug Applications and 97...

Science.gov (United States)

2011-06-08

... Promius Pharma, LLC, mononitrate) 200 Somerset Tablets, 20 mg. Corporate Blvd., 7th Floor, Bridgewater, NJ.... Suspension. NDA 050560 Cefizox (ceftizoxime Astellas Pharma US, sodium) Powder for Inc., 3 Parkway Injection... USP, EQ 500 mg (base) and 1 gram (g) (base) Vials. ANDA 063294 Cefizox (ceftizoxime Astellas Pharma US...

About opportunity and advantages of adaptation the system of education of experts on atomic engineering specialty in Odessa Polytechnic University to the European system of education

International Nuclear Information System (INIS)

Mazurenko, A.

2004-01-01

Education of experts for atomic engineering in Odessa Polytechnic University is conducted for almost thirty years and has developed traditions. Approaching of education systems of experts of Ukraine and Europe inevitably in the modern integrated world including nuclear engineering. Thus it is necessary to take into account experience of progressive World and European countries and Eastern Europe countries - Russia and Ukraine. Creation of All-European Methodical Center for coordination of education of experts for Nuclear industry with the main functions - coordinating, supervising and consulting is expedient. (author)

Dedicated Laboratory Setup for CO2 TEA Laser Propulsion Experiments at Rensselaer Polytechnic Institute

International Nuclear Information System (INIS)

Salvador, Israel I.; Kenoyer, David; Myrabo, Leik N.; Notaro, Samuel

2010-01-01

Laser propulsion research progress has traditionally been hindered by the scarcity of photon sources with desirable characteristics, as well as integrated specialized flow facilities in a dedicated laboratory environment. For TEA CO 2 lasers, the minimal requirements are time-average powers of >100 W), and pulse energies of >10 J pulses with short duration (e.g., 0.1 to 1 μs); furthermore, for the advanced pulsejet engines of interest here, the laser system must simulate pulse repetition frequencies of 1-10 kilohertz or more, at least for two (carefully sequenced) pulses. A well-equipped laser propulsion laboratory should have an arsenal of sensor and diagnostics tools (such as load cells, thrust stands, moment balances, pressure and heat transfer gages), Tesla-level electromagnet and permanent magnets, flow simulation facilities, and high-speed visualization systems, in addition to other related equipment, such as optics and gas supply systems. In this paper we introduce a cutting-edge Laser Propulsion Laboratory created at Rensselaer Polytechnic Institute, one of the very few in the world to be uniquely set up for beamed energy propulsion (BEP) experiments. The present BEP research program is described, along with the envisioned research strategy that will exploit current and expanded facilities in the near future.

The development of performance-based practical assessment model at civil engineering workshop in state polytechnic

Science.gov (United States)

Kristinayanti, W. S.; Mas Pertiwi, I. G. A. I.; Evin Yudhi, S.; Lokantara, W. D.

2018-01-01

Assessment is an important element in education that shall oversees students’ competence not only in terms of cognitive aspect, but alsothe students’ psychomotorin a comprehensive way. Civil Engineering Department at Bali State Polytechnic,as a vocational education institution, emphasizes on not only the theoretical foundation of the study, but also the application throughpracticum in workshop-based learning. We are aware of a need for performance-based assessment for these students, which would be essential for the student’s all-round performance in their studies.We try to develop a performance-based practicum assessment model that is needed to assess student’s ability in workshop-based learning. This research was conducted in three stages, 1) learning needs analysis, 2) instruments development, and 3) testing of instruments. The study uses rubrics set-up to test students’ competence in the workshop and test the validity. We obtained 34-point valid statement out of 35, and resulted in value of Cronbach’s alpha equal to 0.977. In expert test we obtained a value of CVI = 0.75 which means that the drafted assessment is empirically valid within thetrial group.

A concepção de politecnia em Moçambique: contradições de um discurso socialista (1983-1992 The idea of polytechnicalism in Mozambique: contradictions of a socialist discourse (1983-1992

Directory of Open Access Journals (Sweden)

António Cipriano Parafino Gonçalves

2007-12-01

Full Text Available O trabalho analisa a fundamentação do conceito de politecnia na educação moçambicana, de acordo com o projeto político proposto pela Frente de Libertação de Moçambique (Frelimo, que preconizava a instauração de uma sociedade socialista nesse país. Definida nos documentos oficiais como tradução do princípio pedagógico de ligação entre a teoria e a prática, entre a escola e o trabalho, a politecnia deveria permear todo o processo de formação escolar e visava propiciar aos alunos bases para compreender a realidade, assimilar o conhecimento científico e transformar a natureza e a sociedade. Metodologicamente, foi realizada uma pesquisa teórica, revisando a bibliografia sobre o surgimento do conceito de politecnia, o entendimento deste em Marx, Lênin e no movimento operário russo. Também foram consultados documentos oficiais, artigos, livros e resultados de pesquisas sobre a educação socialista moçambicana que focassem o propósito da pesquisa. Empiricamente, realizaram-se entrevistas com intelectuais que estiveram envolvidos com a educação moçambicana no período recortado (1983-1992, na cidade de Maputo, entre janeiro e março de 2005. Da análise de dados e do conteúdo das entrevistas, conclui-se, primeiro, que existe uma diferença na fundamentação da concepção de educação politécnica na proposta pedagógica de Moçambique em relação às propostas sejam de Marx e Lênin. Segundo, que o entendimento do conceito de politecnia em Moçambique foi limitado e que o discurso socialista que acompanhou a educação moçambicana foi contraditório.The work analyzes the grounding of the concept of polytechnicalism in Mozambican education, according to the political project proposed by the Mozambican Liberation Front (FRELIMO, which defended the establishment of a socialist nation in that country. Defined in the official documents as a translation of the pedagogical principle of the connection between theory and

High performance in silico virtual drug screening on many-core processors

Science.gov (United States)

Price, James; Sessions, Richard B; Ibarra, Amaurys A

2015-01-01

Drug screening is an important part of the drug development pipeline for the pharmaceutical industry. Traditional, lab-based methods are increasingly being augmented with computational methods, ranging from simple molecular similarity searches through more complex pharmacophore matching to more computationally intensive approaches, such as molecular docking. The latter simulates the binding of drug molecules to their targets, typically protein molecules. In this work, we describe BUDE, the Bristol University Docking Engine, which has been ported to the OpenCL industry standard parallel programming language in order to exploit the performance of modern many-core processors. Our highly optimized OpenCL implementation of BUDE sustains 1.43 TFLOP/s on a single Nvidia GTX 680 GPU, or 46% of peak performance. BUDE also exploits OpenCL to deliver effective performance portability across a broad spectrum of different computer architectures from different vendors, including GPUs from Nvidia and AMD, Intel’s Xeon Phi and multi-core CPUs with SIMD instruction sets. PMID:25972727

Tests of a high rate pixel detector for CMS upgrade

Energy Technology Data Exchange (ETDEWEB)

Mersi, Stefano [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States). et al.

2013-07-13

This is a Technical Scope of Work (TSW) between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of the CMS Pixel group, which consists of individuals from the Bristol University, CERN, Fermilab, Rutherford Laboratory (UK), and National Taiwan University who have committed to participate in beam tests to be carried out during the 2013 - 2014 Fermilab Test Beam Facility program. The TSW is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. It reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this TSW to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. This TSW fulfills Article 1 (facilities and scope of work) of the User Agreements signed (or still

Uranium hexaflouride freezer/sublimer process simulator/trainer

International Nuclear Information System (INIS)

Carnal, C.L.; Belcher, J.D.; Tapp, P.A.; Ruppel, F.R.; Wells, J.C.

1991-01-01

This paper describes a software and hardware simulation of a freezer/sublimer unit used in gaseous diffusion processing of uranium hexafluoride (UF 6 ). The objective of the project was to build a plant simulator that reads control signals and produces plant signals to mimic the behavior of an actual plant. The model is based on physical principles and process data. Advanced Continuous Simulation Language (ACSL) was used to develop the model. Once the simulation was validated with actual plant process data, the ACSL model was translated into Advanced Communication and Control Oriented Language (ACCOL). A Bristol Babcock Distributed Process Controller (DPC) Model 3330 was the hardware platform used to host the ACCOL model and process the real world signals. The DPC will be used as a surrogate plant to debug control system hardware/software and to train operators to use the new distributed control system without disturbing the process. 2 refs., 4 figs

Translational research needs us to go back to basics and collaborate: interview with Lars Sundstrom.

Science.gov (United States)

Sundstrom, Lars

2016-09-01

Lars Sundstrom is Director of Enterprise and Translation at the West of England Academic Health Sciences Network [1] (UK), a Professor of Practice in Translational Medicine and Co-Director of the Elizabeth Blackwell Institute for Health Research at Bristol University [2] (UK), and an honorary Professor of Medicine at Cardiff University (UK). He has extensive experience in translational medicine and clinical neurosciences, holding positions at several eminent universities. He has also held executive and board-level positions at several SMEs, developing new therapeutics for neurological conditions and tools for drug discovery. He has also been an advisor to several UK and local government task forces and to the European Commission and the European Federation of Pharmaceutical Industry Associations. He was a founding member of the European Brain Council in Brussels, and set up the Severnside Alliance for Translational Research, developing a regional network partnership to link clinical and basic scientists. He was also involved in the creation of Health Research Wales.

High performance in silico virtual drug screening on many-core processors.

Science.gov (United States)

McIntosh-Smith, Simon; Price, James; Sessions, Richard B; Ibarra, Amaurys A

2015-05-01

Drug screening is an important part of the drug development pipeline for the pharmaceutical industry. Traditional, lab-based methods are increasingly being augmented with computational methods, ranging from simple molecular similarity searches through more complex pharmacophore matching to more computationally intensive approaches, such as molecular docking. The latter simulates the binding of drug molecules to their targets, typically protein molecules. In this work, we describe BUDE, the Bristol University Docking Engine, which has been ported to the OpenCL industry standard parallel programming language in order to exploit the performance of modern many-core processors. Our highly optimized OpenCL implementation of BUDE sustains 1.43 TFLOP/s on a single Nvidia GTX 680 GPU, or 46% of peak performance. BUDE also exploits OpenCL to deliver effective performance portability across a broad spectrum of different computer architectures from different vendors, including GPUs from Nvidia and AMD, Intel's Xeon Phi and multi-core CPUs with SIMD instruction sets.

Ixabepilone: a new treatment option for the management of taxane-resistant metastatic breast cancer

International Nuclear Information System (INIS)

Cobham, Marta Vallee; Donovan, Diana

2009-01-01

Ixabepilone (Ixempra ® ; Bristol-Myers Squibb) is a novel microtubule stabilizing agent recently approved for the treatment of metastatic breast cancer (MBC). This article focuses on considerations for ixabepilone administration and adverse event (AE) management, drawing from the biomedical literature indexed in PubMed, published abstracts from the American Society of Clinical Oncology annual meetings, and the manufacturer’s prescribing information for ixabepilone. Administered as monotherapy or in combination with capecitabine in clinical studies, ixabepilone demonstrated positive clinical response rates, prolonged progression-free survival, and a favorable safety profile in patients with MBC. Treatment-related AEs were predictable and manageable with dose modification, treatment interruption, and active management. As ixabepilone undergoes development in earlier lines of breast cancer therapy and in other solid tumors, oncology nurses will encounter more and more patients receiving ixabepilone therapy. If nurses are acquainted with the unique management strategies associated with ixabepilone treatment, as detailed herein, patients are more likely to receive the full benefit of therapy

Radiocaesium in the seas of northern Europe: 1980-84

International Nuclear Information System (INIS)

Camplin, W.C.; Steele, A.K.

1991-01-01

A computer data base of measurements of caesium-134 and caesium-137 in sea water has been compiled. The measurements were carried out by the UK Ministry of Agriculture, Fisheries and Food and include data for the Irish Sea, Bristol Channel, English Channel, North Sea, Scottish waters and other parts of the marine environment of northern Europe. This report covers the sampling period 1980-84 and further information will be published as the data base is expanded. It is hoped that the information will be useful to scientists modelling radionuclide dispersion in the area. In order to assist in the development of new models, diskettes of the data in ASCII files are available, on request, from the first author. The data include the locations of sample collection, collection date, depth salinity, concentration of activity and counting errors. Plots of the geographical scope of the data are also provided to assist the user. (author)

Infinite potential the life and times of David Bohm

CERN Document Server

Peat, David

1997-01-01

Throughout his life, David Bohm felt himself to be different, and this was reflected in his lifestyle and in his physics. His life was one of unfulfilled searching. If one compares mainstream physics to the church, with a solid hierarchy of cardinals, archbishops and bishops, Bohm was an ascetic hermit who would occasionally come in from the wilderness with a compelling message, only to disappear again. Bohmian quantum mechanics is not part of mainstream physics, but for those who do cross over, like John Bell, the commitment can be rewarding. In the post-war 'Un-American Activities' purge, Bohm lost a prestigious job at Princeton and t emporarily his US citizenship, and his nomadic career took him to Brazil, Israel and Bristol before he finally settled in London's Birkbeck College. A sensitive-written book about a gifted, unusual and sometimes provocative figure. The interaction between Bohm and Oppenheimer is especially interesting, while Bohm's later life was bizarre.

2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph.

Science.gov (United States)

Meanwell, Nicholas A

2016-08-25

The development of direct-acting antiviral agents that can cure a chronic hepatitis C virus (HCV) infection after 8-12 weeks of daily, well-tolerated therapy has revolutionized the treatment of this insidious disease. In this article, three of Bristol-Myers Squibb's HCV programs are summarized, each of which produced a clinical candidate: the NS3 protease inhibitor asunaprevir (64), marketed as Sunvepra, the NS5A replication complex inhibitor daclatasvir (117), marketed as Daklinza, and the allosteric NS5B polymerase inhibitor beclabuvir (142), which is in late stage clinical studies. A clinical study with 64 and 117 established for the first time that a chronic HCV infection could be cured by treatment with direct-acting antiviral agents alone in the absence of interferon. The development of small molecule HCV therapeutics, designed by medicinal chemists, has been hailed as "the arc of a medical triumph" but may equally well be described as "the arc of a medicinal chemistry triumph".

Scoping study into community-based renewable energy projects

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

This scoping study has been carried out by the Centre for Sustainable Energy (CSE), a charity which promotes energy efficiency and renewable energy. CSE have used their involvement in the development of the Energy Club (the first energy service company for householders in the UK) and the Bristol Environment and Energy Trust (a cross-sector organisation initiating environmental projects) as the basis of the study. This study is the first phase of a long term project to set up two small-scale renewable energy schemes to demonstrate the benefits of a community based approach. Specific objectives of the study were: to identify, quantify and cost, renewable energy resources for interested community organisations; to evaluate two routes for developing community based projects - Environment Trusts and Energy Clubs'; to organise a seminar with the objective of bringing together community interest groups with experts in renewable energy; to identify two communities with viable renewable projects for the next phase - full feasibility studies/pilot projects. (author)

Alaskan Salmon and Gen R: hunting, fishing to cultivate ecological mindfulness

Science.gov (United States)

Mueller, Michael P.

2015-03-01

Can mining and fisheries co-exist in Bristol Bay, Alaska? To delve into this interesting tension, I expand on Clay Pierce's (this special issue) thoughtful analysis of genetically modified salmon and AquaBounty Technologies, where he explores actor-network theory in relation to scientific literacy and schooling. Further, my essay explores the idea of embodied knowledge as paramount to the next generation of youth engaged with scientific literacy. I demonstrate the problems associated with using hegemonic science to normalize biocapitalism and the subjugated knowledges in relation. Ultimately, I provide justifications for strengthening an ecologically mindful scientific literacy, working towards what might be called "Neptunian democracy" in science education, including salmon and other nonhuman actors as integral for youth wrestling with ecojustice issues. To do this, I highlight the significance of renewing fishing, hunting, and salmon eating. These things ought to become an intimate characteristic of the imagined literacy of the next generation of youth (what I've been calling Generation R for responsibility).

Impact of the Sea Empress oil spill on lysosomal stability in mussel blood cells.

Science.gov (United States)

Fernley, P W; Moore, M N; Lowe, D M; Donkin, P; Evans, S

2000-01-01

Coastal zones are among the most productive and vulnerable areas on the planet. An example of impact on these fragile environments was shown in the case of the "Sea Empress" oil tanker, which ran aground in the Bristol Channel in 1996, spilling 72,000 tons of "Forties" crude oil. The objective was to investigate the sub-lethal cellular pathology and tissue hydrocarbon contamination in marine mussel populations, 4 months after the initial spill, using the neutral red retention (NRR) assay for lysosomal stability in blood cells. NRR was reduced in mussels, and indicative of cell injury, from the two sites closest to the spill in comparison with more distant and reference sites. Lysosomal stability was inversely correlated with polycyclic aromatic hydrocarbon concentrations in mussel tissues. Reduced lysosomal stability has previously been shown to contribute to impaired immunocompetence and to autophagic loss of body tissues. The use of this type of technique is discussed in the context of cost-effective, ecotoxicological tools for Integrated Coastal Zone Management.

Impact of the Sea Empress oil spill on lysosomal stability in mussel blood cells

International Nuclear Information System (INIS)

Fernley, P.W.; Lowe, D.M.; Donkin, P.; Evans, S.

2000-01-01

Coastal zones are among the most productive and vulnerable areas on the planet. An example of impact on these fragile environments was shown in the case of the Sea Empress oil tanker, which ran aground in the Bristol Channel in 1996, spilling 72,000 tonnes of Forties crude oil. The objective was to investigate the sub-lethal cellular pathology and tissue hydrocarbon contamination in marine mussel populations, 4 months after the initial spill, using the neutral red retention (NRR) assay for lysosomal stability in blood cells. NRR was reduced in mussels, and indicative of cell injury, from the two sites closest to the spill in comparison with more distant and reference sites. Lysosomal stability was inversely correlated with polycyclic aromatic hydrocarbon concentrations in mussel tissues. Reduced lysosomal stability has previously been shown to contribute to impaired immunocompetence and to autophagic loss of body tissues. The use of this type of technique is discussed in the context of cost-effective, ecotoxicological tools for Integrated Coastal Zone Management. (Author)

Impact of the Sea Empress oil spill on lysosomal stability in mussel blood cells

Energy Technology Data Exchange (ETDEWEB)

Fernley, P.W.; Lowe, D.M.; Donkin, P.; Evans, S. [Plymouth Marine Lab. (United Kingdom). Centre for Coastal and Marine Sciences; Moore, M.N. [Plymouth Marine Lab. (United Kingdom). Centre for Coastal and Marine Sciences; UNIDO, SES/PEM, Vienna International Centre (Austria)

2000-07-01

Coastal zones are among the most productive and vulnerable areas on the planet. An example of impact on these fragile environments was shown in the case of the Sea Empress oil tanker, which ran aground in the Bristol Channel in 1996, spilling 72,000 tonnes of Forties crude oil. The objective was to investigate the sub-lethal cellular pathology and tissue hydrocarbon contamination in marine mussel populations, 4 months after the initial spill, using the neutral red retention (NRR) assay for lysosomal stability in blood cells. NRR was reduced in mussels, and indicative of cell injury, from the two sites closest to the spill in comparison with more distant and reference sites. Lysosomal stability was inversely correlated with polycyclic aromatic hydrocarbon concentrations in mussel tissues. Reduced lysosomal stability has previously been shown to contribute to impaired immunocompetence and to autophagic loss of body tissues. The use of this type of technique is discussed in the context of cost-effective, ecotoxicological tools for Integrated Coastal Zone Management. (Author)

MammoGrid: a mammography database

CERN Multimedia

2002-01-01

What would be the advantages if physicians around the world could gain access to a unique mammography database? The answer may come from MammoGrid, a three-year project under the Fifth Framework Programme of the EC. Led by CERN, MammoGrid involves the UK (the Universities of Oxford, Cambridge and the West of England, Bristol, plus the company Mirada Solutions of Oxford), and Italy (the Universities of Pisa and Sassari and the Hospitals in Udine and Torino). The aim of the project is, in light of emerging GRID technology, to develop a Europe-wide database of mammograms. The database will be used to investigate a set of important healthcare applications as well as the potential of the GRID to enable healthcare professionals throughout the EU to work together effectively. The contributions of the partners include building the GRID-database infrastructure, developing image processing and Computer Aided Detection techniques, and making the clinical evaluation. The first project meeting took place at CERN in Sept...

XML and Graphs for Modeling, Integration and Interoperability:a CMS Perspective

CERN Document Server

van Lingen, Frank

2004-01-01

This thesis reports on a designer's Ph.D. project called “XML and Graphs for Modeling, Integration and Interoperability: a CMS perspective”. The project has been performed at CERN, the European laboratory for particle physics, in collaboration with the Eindhoven University of Technology and the University of the West of England in Bristol. CMS (Compact Muon Solenoid) is a next-generation high energy physics experiment at CERN, which will start running in 2007. The complexity of such a detector used in the experiment and the autonomous groups that are part of the CMS experiment, result in disparate data sources (different in format, type and structure). Users need to access and exchange data located in multiple heterogeneous sources in a domain-specific manner and may want to access a simple unit of information without having to understand details of the underlying schema. Users want to access the same information from several different heterogeneous sources. It is neither desirable nor fea...

Tea with Mother: Sarah Palin and the Discourse of Motherhood as a Political Ideal

Directory of Open Access Journals (Sweden)

Janet McCabe

2016-02-01

Full Text Available Seldom has someone emerged so unexpectedly and sensationally on to the American political scene as Sarah Palin. With Palin came what had rarely, if ever, been seen before on a presidential trail: hockey moms, Caribou-hunting, pitbulls in lipstick parcelled as political weaponry. And let’s not forget those five children, including Track 19, set to deploy to Iraq, Bristol, and her unplanned pregnancy at 17, and Trig, a six-month-old infant with Down’s syndrome. Never before had motherhood been so finely balanced with US presidential politics. Biological vigour translated into political energy, motherhood transformed into an intoxicating political ideal. This article focuses on Sarah Palin and how her brand of “rugged Alaskan motherhood” (PunditMom 2008 became central to her media image, as well as what this representation has to tell us about the relationship between mothering as a political ideal, US politics, and the media.

Heat dispersion in rivers

International Nuclear Information System (INIS)

Shaw, T.L.

1974-01-01

One of the tasks of the Sonderforschungsbereich 80 is to study the dispersion of heat discharged into rivers and other bodies of water and to develop methods which permit prediction of detrimental effects caused by the heated discharges. In order to help the SFB 80 to specify this task, Dr. Shaw, lecturer of Civil Engineering at the Bristol University, conducted a literature survey on heat-dispersion studies during the two months which he spent as a visiting research fellow with the SFB 80 at the University of Karlsruhe in the summer of 1973. The following report is the outcome of this survey. It gives Dr. Shaw's assessment of the present state of knowledge - based almost exclusively on literature in the English language - and compares this with the knowledge required by river planners. The apparent discrepancy leads to suggestions for future research. Selected references as well as a representative bibliography can be found at the end of the report. (orig.) [de

Design and Implementation of Integrated Software Research and Community Service at State Polytechnic of Manado

Science.gov (United States)

Saroinsong, T.; A. S Kondoj, M.; Kandiyoh, G.; Pontoh, G.

2018-01-01

The State Polytechnic of Manado (Polimdo) is one of the reliable institutions in North Sulawesi that first implemented ISO 9001. But the accreditation of the institution has not been satisfactory, it means there is still much to be prepared to achieve the expected target. One of the criteria of assessment of institutional accreditation is related to research activities and social work in accordance with the standard seven. Data documentation systems related to research activities and social work are not well integrated and well documented in all existing work units. This causes the process of gathering information related to the activities and the results of research and social work in order to support the accreditation activities of the institution is still not efficient. This study aims to build an integrated software in all work units in Polimdo to obtain documentation and data synchronization in support of activities or reporting of documents accreditation institution in accordance with standard seven specifically in terms of submission of research proposal and dedication. The software will be developed using RUP method with analysis using data flow diagram and ERM so that the result of this research is documentation and synchronization of data and information of research activity and community service which can be used in preparing documents report for accreditation institution.

The views of part-time clinical teachers regarding their role in undergraduate education at the University of Bristol Dental School.

Science.gov (United States)

Puryer, J; McNally, L; O'Sullivan, D

2015-01-01

UK dental schools are reliant on part-time teachers to deliver the clinical educational component of the course, the majority with a background in general dental practice. Opportunities for promotion are limited, as is the support for obtaining educational qualifications. The aim of this study was to ascertain the views of such teachers at a dental school. An anonymous online survey was used to obtain both qualitative and quantitative views. The response rate was 80%. The school has n = 50 part-time clinical teachers, who have been teaching for, on average ten years, and for three sessions per week. Eighteen percent of teachers are recognised specialists. Forty-six percent of respondents have a formal teaching qualification, mostly at certificate level, and 55% thought it necessary to acquire a formal teaching qualification. Eighty-eight percent were happy with their role as clinical teachers. This study demonstrates that despite the lack of support and prospect of career progression, the majority of part-time clinical teachers at this institution are satisfied with their role.

Soil Survey Geographic (SSURGO) Special Point Features for the State of Rhode Island: Bristol, Kent, Newport, Providence, and Washington Counties

Data.gov (United States)

University of Rhode Island Geospatial Extension Program — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

Soil Survey Geographic (SSURGO) Special Line Features for the State of Rhode Island: Bristol, Kent, Newport, Providence, and Washington County

Data.gov (United States)

University of Rhode Island Geospatial Extension Program — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

Successful Aging through the Eyes of Alaska Native Elders. What It Means to Be an Elder in Bristol Bay, AK

Science.gov (United States)

Lewis, Jordan P.

2011-01-01

Purpose: Alaska Natives (ANs) view aging from a holistic perspective, which is not typical of the existing successful aging literature. One of the challenges of conducting research with cultural groups (e.g., ANs) is the lack of data, or research, on culture and aging and its impact on how we view successful aging. This research explores…

The GENIUS-test-facility--first results on background from {sup 222}Rn daughters

Energy Technology Data Exchange (ETDEWEB)

Klapdor-Kleingrothaus, H.V. E-mail: H.Klapdor@mpi-hd.mpg.dehttp://www.mpi-hd.mpg.de.non_acc; Tomei, C.; Krivosheina, I.V.; Chkvorets, O

2004-09-11

GENIUS-TF (Nucl. Instr. and Meth. A 511 (2003) 341; Nucl. Instr. and Meth. A 481 (2002) 149.) is a test-facility for the GENIUS project (GENIUS-Proposal, 20 November 1997; Z. Phys. A 359 (1997) 351; CERN Courier, November 1997, 16; J. Phys. G 24 (1998) 483; Z. Phys. A 359 (1997) 361; in: H.V. Klapdor-Kleingrothaus, H. Pas. (Eds.), First International Conference on Particle Physics Beyond the Standard Model, Castle Ringberg, Germany, 8-14 June 1997, IOP Bristol (1998) 485 and in Int. J. Mod. Phys. A 13 (1998) 3953; in: H.V. Klapdor-Kleingrothaus, I.V. Krivosheina (Eds.), Proceedings of the Second International Conference on Particle Physics Beyond the Standard Model BEYOND' 99, Castle Ringberg, Germany 6-12 June 1999, IOP Bristol (2000) 915), a proposed large scale underground observatory for rare events which is based on operation of naked germanium detectors in liquid nitrogen for an extreme background reduction. Operation of naked Ge crystals in liquid nitrogen has been applied routinely already for more than 20 years by the CANBERRA Company for technical functions tests (CANBERRA Company, private communication, 5 March 2004.), but it never had found entrance into basic research. Only in 1997 first tests of application of this method for nuclear spectroscopy have been performed, successfully, in Heidelberg (Klapdor-Kleingrothaus et al., 1997, 1998; J. Hellmig and H.V. Klapdor-Kleingrothaus, 1997). On May 5, 2003 the first four naked high-purity germanium detectors (total mass 10.52 kg) were installed in liquid nitrogen in the GENIUS Test Facility at the Gran Sasso underground laboratory. Since then the experiment has been running continuously, testing for the first time the novel technique in an underground laboratory and for a long-lasting period. In this work, we present the first analysis of the GENIUS-TF background after the completion of the external shielding, which took place in December 2003. We focus especially on the background coming from {sup 222

The GENIUS-test-facility--first results on background from 222Rn daughters

International Nuclear Information System (INIS)

Klapdor-Kleingrothaus, H.V.; Tomei, C.; Krivosheina, I.V.; Chkvorets, O.

2004-01-01

GENIUS-TF (Nucl. Instr. and Meth. A 511 (2003) 341; Nucl. Instr. and Meth. A 481 (2002) 149.) is a test-facility for the GENIUS project (GENIUS-Proposal, 20 November 1997; Z. Phys. A 359 (1997) 351; CERN Courier, November 1997, 16; J. Phys. G 24 (1998) 483; Z. Phys. A 359 (1997) 361; in: H.V. Klapdor-Kleingrothaus, H. Pas. (Eds.), First International Conference on Particle Physics Beyond the Standard Model, Castle Ringberg, Germany, 8-14 June 1997, IOP Bristol (1998) 485 and in Int. J. Mod. Phys. A 13 (1998) 3953; in: H.V. Klapdor-Kleingrothaus, I.V. Krivosheina (Eds.), Proceedings of the Second International Conference on Particle Physics Beyond the Standard Model BEYOND' 99, Castle Ringberg, Germany 6-12 June 1999, IOP Bristol (2000) 915), a proposed large scale underground observatory for rare events which is based on operation of naked germanium detectors in liquid nitrogen for an extreme background reduction. Operation of naked Ge crystals in liquid nitrogen has been applied routinely already for more than 20 years by the CANBERRA Company for technical functions tests (CANBERRA Company, private communication, 5 March 2004.), but it never had found entrance into basic research. Only in 1997 first tests of application of this method for nuclear spectroscopy have been performed, successfully, in Heidelberg (Klapdor-Kleingrothaus et al., 1997, 1998; J. Hellmig and H.V. Klapdor-Kleingrothaus, 1997). On May 5, 2003 the first four naked high-purity germanium detectors (total mass 10.52 kg) were installed in liquid nitrogen in the GENIUS Test Facility at the Gran Sasso underground laboratory. Since then the experiment has been running continuously, testing for the first time the novel technique in an underground laboratory and for a long-lasting period. In this work, we present the first analysis of the GENIUS-TF background after the completion of the external shielding, which took place in December 2003. We focus especially on the background coming from 222 Rn

The Riverscape Analysis Project: Using Remote Sensing to Leverage Salmon Science and Management Applications Around the Pacific Rim

Science.gov (United States)

Chilcote, S.; Maumenee, N.; Lucotch, J.; Whited, D.; Bansack, T.; Kimball, J. S.; Stanford, J.

2009-12-01

The Salmonid Rivers Observatory Network (SaRON) is an intensive field research project which aims to describe the relation between salmon productivion and diversity in relation to environmental drivers and physical complexity of riverine shifting habitat mosaics. The Riverscape Analysis Project (RAP) is a spatially explicit remote sensing database which quantifies and ranks different combinations of physical landscape metrics around the Pacific Rim, displaying results through a publically accessible web based decision support framework designed to empower regional management and conservation efforts for wild salmon. The objective of our research is to explicitly describe and relate different habitat types and their potential fish production at a variety of scales and throughout the range of Pacific salmon, leveraging our field research through available satellite remote sensing and geospatial analysis. We find that rivers exhibit a range of physical, chemical, and biotic conditions consistent with the shifting habitat mosaic (SHM) concept. Landscape physical variables derived from global Landsat imagery and SRTM-DEM information explain 93.2% of observed variability in over 1500 watersheds across the Pacific Rim. We expect that it is these coarse scale differences in river typologies which are responsible for the fine scale differences in habitat conditions and juvenile salmon production. Therefore, we ranked rivers using landscape scale physical variables to prioritize them for management actions based on potential productivity. For example, the Kvichak River of Bristol Bay is highly ranked, 8th, based on its physical landscape structure as well as current human impacts. Currently, the Bristol Bay fishery is extremely productive. Habitat structure can be used not only to define reference conditions and management targets for how many fish we would expect a river to produce based on its potential habitat capacity, but it also provides new analytical tools to

Azúcar y Modernidad: La experimentación tecnológica de la oligarquía habanera: 1700-1820

Directory of Open Access Journals (Sweden)

García Rodríguez, Mercedes

2012-12-01

Full Text Available The article discusses the mentality of modernization and technological experimentation which accompanied the enlightened elite of the Cuban sugar-producing oligarchy in the Eighteenth and Nineteenth Centuries. Data and documents show this powerful Havana group’s noted interest in increasing the production of the sweet produce, what drove them to engage with English factories to produce modern-designed milis and construction materials that made them more durable and powerful. We’ll show the diligence and persistence of the sugar-producing elite to achieve its economic and political goals and how through their spokesman Francisco de Arango y Parreño they demanded the King’s permission for a technologicalindustrial espionage trip through Europe and the Caribbean that helped them to introduce new machines and modern technology. The investment capital accumulated by some members of the elite and the negotiations of the management of the Royal Trading Company of Havana in Cádiz, Bristol and London were fundamental to this process.

El artículo aborda la mentalidad de modernización y experimentación tecnológica que acompañó a la élite ilustrada de la oligarquía azucarera de Cuba entre los siglos XVIII y XIX. Se demuestra con datos y documentos el marcado interés de este poderoso grupo habanero por hacer crecer la producción del dulce, lo que los condujo a contratar, con fábricas inglesas, la producción de los molinos con un diseño moderno, y materiales constructivos que los hicieron más duraderos y potentes. Mostraremos la diligencia y persistencia de la élite azucarera para lograr sus objetivos económicos y políticos y cómo a través de su vocero Francisco de Arango y Parreño reclamaron al rey autorización para un periplo por Europa y el Caribe de espionaje tecnológico-industrial que les sirvió para introducir nuevas máquinas y tecnología moderna. En este proceso fue fundamental la inversión del capital acumulado

Exploring the relationship between maternal iron status and offspring’s blood pressure and adiposity: a Mendelian randomization study

Directory of Open Access Journals (Sweden)

Alwan NA

2012-08-01

Full Text Available Nisreen A Alwan,1 Debbie A Lawlor,2 Harry J McArdle,3 Darren C Greenwood,4 Janet E Cade11Nutritional Epidemiology Group, School of Food Science and Nutrition, University of Leeds, Leeds, UK; 2MRC Centre for Causal Analyses in Translational Research, University of Bristol, Bristol; 3Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen; 4Biostatistics Unit, Leeds Institute for Health, Genetics and Therapeutics, University of Leeds, Leeds, UKBackground: Iron deficiency is the most common micronutrient deficiency worldwide. Experimental animal studies suggest that mothers deficient in iron during pregnancy are more likely to have offspring who become obese with high blood pressure. C282Y mutation carriers are more likely to have higher iron stores.Methods: We undertook an instrumental variable (IV analysis, using maternal C282Y as an indicator for the mother’s iron status, to examine its association with offspring blood pressure (BP, waist circumference (WC, and body mass index (BMI, and compared the results to that of ordinary least squares (OLS regression. Offspring of a sub-cohort of mothers from the UK Women’s Cohort Study (UKWCS were recruited in 2009–2010 (n = 348, mean age = 41 years. Their blood pressure, height, and weight were measured at their local general medical practice, and they were asked to self-measure their waist circumference. About half were offspring of C282Y carriers. Maternal ferritin was used as a biomarker of maternal iron status.Results: Maternal C282Y was strongly associated with maternal ferritin (mean difference per allele = 84 g/L, 95% confidence interval: 31–137, P = 0.002. Using IV analyses, maternal ferritin was not linked to offspring’s BP, BMI, or WC. The first stage F-statistic for the strength of the instrument was 10 (Kleibergen–Paap rk LM P = 0.009. Maternal ferritin was linked to offspring diastolic BP, WC, and BMI in univariable, but not in multivariable OLS analysis. There

Trade union activity, cultural, public and political life of Krasnoyarsk Polytechnic Institute in the second half of 1950s–1980

Directory of Open Access Journals (Sweden)

Petrik Valeriy V.

2016-01-01

Full Text Available Basing on rich documentary, the article studies the activity of the trade union organization in Krasnoyarsk Polytechnic Institute and the impact the trade union had on the cultural, public and political life of the Institute in the second half of the 1950s-1980s. The activity is stated to be held in different forms and areas: amateur arts, propaganda, wall-newspaper and house magazine, vigilant groups, University of Culture, student club, lecturing agitation group, student construction brigades, department, groups and hostels competitions. The authors come to the conclusion that involving students and faculty members into cultural, public and political life added greatly to fostering the future engineers as it took them less time to adapt to the team-spirited workforce after graduating from the higher educational establishment. The article is intended for the people interested in history of higher education in Siberia and Russia.

Education of specialists-cartographers in Lviv Polytechnic National University

Directory of Open Access Journals (Sweden)

Наталія Ярема

2017-09-01

Full Text Available This paper describes the system of future specialists-cartographers education in Lviv polytechnic national university. Main targets of the department of cartography and geospatial modelling are listed. Key research areas of the department, the educational specifics of students at «Bachelor» and «Master‘s» levels are described. At present, the main task of the department is to train specialists with good knowledge of cartographic investigation method, GIS technologies, because digital cartography, web-mapping, web-portal are things of the future. Cartography specialists must know how to create traditional maps (topographic, thematic, tourist using computer technologies and electronic maps that can be used in the creation of GIS systems, informational resources in navigation, military affairs and so on. The main scientific direction of the department is general geographic and thematic mapping, GIS mapping and development of GIS, history of the cartography, mathematic modelling in geodesy, astronomy and geophysics. The department trains bachelors on specialty 103 «Earth sciences», specialization 103.02 «Cartography». The feature of master’s education is maximum approach to education content for future employment. Master degree students are improving their professional knowledge and skills received during their study for the bachelor’s degree. They are deeply studying modern methods of cartographic digital terrain models with GIS technologies, combining their work with development of cartographic databases. They get acquainted with the principles of base sets of geospatial data, conduct thematic evaluation and forecast maps, using GIS. The students also study methods and order of design, edition, and maps development in detail. Modern mapping needs to be more efficient in the use of both natural and human resources, reflect a complex system man - society - environment. Such problem can be solved using various modeling techniques with

Combined use of the RPI [Rensselaer Polytechnic Institute] reactor for training and critical experiments

International Nuclear Information System (INIS)

Harris, D.R.; Rohr, R.R.; Rodriguez-Vera, F.

1990-01-01

The Rensselaer Polytechnic Institute (RPI) reactor critical facility (RCF) has provided educational and research opportunities for RPI and other students for >25 yr. The RCF was built by the American Locomotive Company (ALCO) in the 1950s as a critical facility in support of the army package power reactor program, and, when ALCO went out of business in 1964, the RCF was acquired by RPI. Since that time, RPI has operated the RCF primarily in a teaching mode in the nuclear engineering department, although reactor research, activation analyses, and reactivity assays have been carried out as well. Until recently, the RCF was fueled by plates containing highly enriched uranium as a cermet in stainless steel. This highly enriched uranium (HEU) fuel was replaced recently by 4.81 wt% enriched UO 2 high-density pellets clad in stainless steel rods. The use of these SPERT (F1) fuel rods in the RCF provided a cost-effective method for conversion of the core from HEU to low-enriched uranium and for enhancement of the RCF training and research program. The RCF is the only facility in the United States that provides reactor training on a core containing fuel that is similar to that used in power industry light water reactors (LWRs). Moreover, the RCF is the only facility in the United States currently available for supplying critical experimental data in support of the LWR power industry. Thus, the RCF is in a unique position to carry out important training and research services consistent with RPI's nuclear engineering objectives

Environment assessment: allocation of petroleum feedstock, Algonquin SNG Inc. , Freetown SNG Plant, Bristol County, MA. [Effects of 100, 78, 49% allocations

Energy Technology Data Exchange (ETDEWEB)

1980-01-01

The proposed administrative action to deny, grant or modify the Algonquin SNG, Inc. (Algonquin) petition for an adjusted allocation of naphtha feedstock may significantly affect the ehuman environment. The volume of feedstock requested is 4,425,571 barrels per year of naphtha to be used in Algonquin's Freetown, MA synthetic natural gas (SNG) plant. Environmental impacts of 100, 78, and 49% allocations were evaluated.

Determination of Appropriate IELTS Writing and Speaking Band Scores for Admission into Two Programs at a Canadian Post-Secondary Polytechnic Institution

Directory of Open Access Journals (Sweden)

Katherine Golder

2011-06-01

Full Text Available Abstract This study aimed to determine the appropriate IELTS band scores in Writing and Speaking for admission to and success in Computer Systems Technology (CST and Computer Information Technology (CIT programs at a large Canadian polytechnic post-secondary institute. A second aim was to explore whether the quality of admissions decisions could be enhanced by aligning their processes more closely with the English language demands of actual tasks required within their target programs. This was done by examining course materials, activities, and assignments in which students are required to read, write, speak, and listen in English and then comparing the required proficiency in English for those tasks to band score descriptors provided by the IELTS measure. Data consisted of student interviews, faculty interviews, observations of lectures and labs, and course documents. Because of the small number of interviewees and the limited depth and scope of content analysis, results should be viewed as indicative rather than conclusive.

Remotely deployable aerial inspection using tactile sensors

Science.gov (United States)

MacLeod, C. N.; Cao, J.; Pierce, S. G.; Sullivan, J. C.; Pipe, A. G.; Dobie, G.; Summan, R.

2014-02-01

For structural monitoring applications, the use of remotely deployable Non-Destructive Evaluation (NDE) inspection platforms offer many advantages, including improved accessibility, greater safety and reduced cost, when compared to traditional manual inspection techniques. The use of such platforms, previously reported by researchers at the University Strathclyde facilitates the potential for rapid scanning of large areas and volumes in hazardous locations. A common problem for both manual and remote deployment approaches lies in the intrinsic stand-off and surface coupling issues of typical NDE probes. The associated complications of these requirements are obviously significantly exacerbated when considering aerial based remote inspection and deployment, resulting in simple visual techniques being the preferred sensor payload. Researchers at Bristol Robotics Laboratory have developed biomimetic tactile sensors modelled on the facial whiskers (vibrissae) of animals such as rats and mice, with the latest sensors actively sweeping their tips across the surface in a back and forth motion. The current work reports on the design and performance of an aerial inspection platform and the suitability of tactile whisking sensors to aerial based surface monitoring applications.

Parental sedentary restriction, maternal parenting style, and television viewing among 10- to 11-year-olds.

Science.gov (United States)

Jago, Russell; Davison, Kirsten K; Thompson, Janice L; Page, Angie S; Brockman, Rowan; Fox, Kenneth R

2011-09-01

To examine whether parenting styles or practices were associated with children's television (TV) viewing. A total of 431 parent-child dyads (10- to 11-year-old children) from Bristol, United Kingdom, were included. Child and parent TV viewing were self-reported and categorized as 4 hours/day. Children reported maternal parenting style (authoritarian, authoritative, or permissive). Child-reported maternal and paternal sedentary restriction scores were combined to create a family-level restriction score. Multinomial logistic regression was used to examine whether child TV viewing was predicted by parenting style or family restriction. A greater proportion of children with permissive mothers watched >4 hours of TV per day, compared with children with authoritarian or authoritative mothers (P = .033). A greater proportion of children for whom both parents demonstrated high restriction watched 4 hours (vs 4 hours of TV per day was 5.2 times higher for children with permissive (versus authoritative) mothers (P = .010). Clinicians need to talk directly with parents about the need to place limitations on children's screen time and to encourage both parents to reinforce restriction messages.

Control of head lice with a coconut-derived emulsion shampoo.

Science.gov (United States)

Connolly, M; Stafford, K A; Coles, G C; Kennedy, C T C; Downs, A M R

2009-01-01

To evaluate a novel coconut-derived emulsion (CDE) shampoo against head lice infestation in children. A school trial in which pupils were treated on days 0 and 7 and checked on days 8 and 15 and a family trial where product was applied by parents three times in 2 weeks or used as a cosmetic shampoo and checked on days 14 and days 70. UK schools in Bristol and Western-super-Mare and families in Northern Somerset. Numbers of children free from infestation after treatment. In the school trial, percentage cures at day 8 were 14% (permethrin, n=7) and 61% (CDE, n=37). In the family trial where all family members were treated, cure rate was 96% (n=28), and if the shampoo was subsequently used as a cosmetic shampoo, only 1 of 12 children became re-infested after 10 weeks. CDE shampoo is a novel effective method of controlling head lice and used after treatment as a cosmetic shampoo can aid in the reduction of re-infestation.

The Relationship Between Utilization of Computer Games and Spatial Abilities Among High School Students

Directory of Open Access Journals (Sweden)

Vahid Motamedi

2015-07-01

Full Text Available This study aimed at investigating the relationship between computer game use and spatial abilities among high school students. The sample consisted of 300 high school male students selected through multi-stage cluster sampling. Data gathering tools consisted of a researcher made questionnaire (to collect information on computer game usage and the Newton and Bristol spatial ability questionnaire with reliability value of .85. Data were analyzed using Pearson’s correlation coefficient. Results showed that there was a meaningful relationship between the use of computer games and spatial ability (r = .59 and p = 00.00, there was a meaningful relationship between the use of computer games and the spatial perceived ability (r = .60 and p = .00, there was a meaningful relationship between the use of computer games and mental rotation ability (r = .48 and p = .00 and there was a meaningful relationship between computer game use and spatial visualization ability (r = .48 and p = .00. In general, the findings showed there was a positive and a significant relationship between the use of computer games and spatial abilities in students.

The development of an innovative approach to postgraduate ultrasound education: An evolving process

International Nuclear Information System (INIS)

Gibbs, Vivien

2011-01-01

Increasing economic pressures on higher education institutions to limit the number of modules offered, together with the conflicting pressure from hospital departments requiring an increasingly skilled and flexible workforce, have resulted in the requirement for a more creative approach to delivery of university postgraduate programmes. One approach implemented at the University of the West of England, Bristol was to extend the role of an Action Based Learning (ABL) module within the Medical Ultrasound programme. Following completion of the first year of this newly accredited module, the experiences of students and staff were evaluated. Results of the evaluation and feedback demonstrated both positive and negative features of this style of learning, and the programme team decided to use this feedback to enhance the student experience for future cohorts undertaking the module. The second delivery of this module is now complete, and the module has again been evaluated. The following article discusses the evolutionary process involved in developing this module, and reviews the enhancements introduced over a two-year period.

From Hippocrates to Commodities: three models of NHS governance: NHS governance, regulation, Mid Staffordshire inquiry, health care as a commodity.

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Newdick, Christopher

2014-01-01

A series of inquiries and reports suggest considerable failings in the care provided to some patients in the NHS. Although the Bristol Inquiry report of 2001 led to the creation of many new regulatory bodies to supervise the NHS, they have never enjoyed consistent support from government and the Mid Staffordshire Inquiry in 2013 suggests they made little difference. Why do some parts of the NHS disregard patients' interests and how we should we respond to the challenge? The following discusses the evolution of approaches to NHS governance through the Hippocratic, Managerial and Commercial models, and assesses their risks and benefits. Apart from the ethical imperative, the need for effective governance is driven both by the growth in information available to the public and the resources wasted by ineffective systems of care. Appropriate solutions depend on an understanding of the perverse incentives inherent in each model and the need for greater sensitivity to the voices of patients and the public. © The Author 2014. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals. permissions@oup.com.

Prevention of brachial plexus injury-12 years of shoulder dystocia training: an interrupted time-series study.

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Crofts, J F; Lenguerrand, E; Bentham, G L; Tawfik, S; Claireaux, H A; Odd, D; Fox, R; Draycott, T J

2016-01-01

To investigate management and outcomes of incidences of shoulder dystocia in the 12 years following the introduction of an obstetric emergencies training programme. Interrupted time-series study comparing management and neonatal outcome of births complicated by shoulder dystocia over three 4-year periods: (i) Pre-training (1996-99), (ii) Early training (2001-04), and (iii) Late training (2009-12). Southmead Hospital, Bristol, UK, with approximately 6000 births per annum. Infants and their mothers who experienced shoulder dystocia. A bi-monthly multi-professional 1-day intrapartum emergencies training course, that included a 30-minute practical session on shoulder dystocia management, commenced in 2000. Neonatal morbidity (brachial plexus injury, humeral fracture, clavicular fracture, 5-minute Apgar score dystocia (resolution manoeuvres performed, traction applied, head-to-body delivery interval). Compliance with national guidance improved with continued training. At least one recognised resolution manoeuvre was used in 99.8% (561/562) of cases of shoulder dystocia in the late training period, demonstrating a continued improvement from 46.3% (150/324, P dystocia. © 2015 Royal College of Obstetricians and Gynaecologists.

FOREWORD: Foreword from Peter Adams Foreword from Peter Adams

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Adams, Peter D.

2009-11-01

As part of this twentieth anniversary special issue I was asked to write a few words about Richard Palmer, the one permanent fixture on the journal over its twenty year history. Richard and I go back a (very) long way! He began his career at IOP Publishing in Bristol in 1971 while my publishing career with the American Physical Society began a little earlier, located at Brookhaven National Laboratory on Long Island NY. Since then, and for nearly forty years we have met often, if irregularly, at many locations throughout the world. As members of two very strong physics organizations we were clearly in competition with each other to seek out and publish the best physics research. At the same time we frequently exchanged experiences and policy ideas for dealing with serious violations of scientific ethical standards and how academic society-run journals can best serve the general scientific community. Overall my relationship with Richard has been a most rewarding one and I shall miss his opinions and sage advice. Richard: Compatriot; competitor; collaborator; I salute you!

Sustainability of NGO capacity building in southern Africa: successes and opportunities.

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Humphries, Debbie; Gomez, Ligia; Hartwig, Kari

2011-01-01

Despite an increase in organizational capacity building efforts by external organizations in low and middle income countries, the documentation of these efforts and their effects on health programs and systems remains limited. This paper reviews key frameworks for considering sustainability of capacity building and applies these frameworks to an evaluation of the sustainability of an AIDS non-governmental organization (NGO) capacity building initiative. From 2004-2007 Bristol-Myers Squibb Foundation's Secure the Future(TM) initiative in southern Africa funded a five country program, the NGO Training Institute (NGOTI), to build capacity of NGOs working to address HIV/AIDS. Lessons learned from this project include issues of ownership, the importance of integrating planning for sustainability within capacity-building projects, and the value of identifying primary capacity-building objectives in order to select sustainability strategies that are focused on maintaining program benefits. Sustainability for capacity building projects can be developed by discussing key issues early in the planning process with all primary stakeholders. Copyright © 2010 John Wiley & Sons, Ltd.

Gazetteer of hydrologic characteristics of streams in Massachusetts; Blackstone River basin

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Wandle, S.W.; Phipps, A.F.

1984-01-01

The Blackstone River basin encompasses 335 square miles in south-central Massachusetts, including parts of Bristol, Middlesex, Norfolk, and Worcester Counties. Drainage areas, using the latest available 1:24,000 scale topographic maps, were computed for the first time for streams draining more than 3 square miles and were recomputed for data-collection sites. Streamflow characteristics, were calculated using a new data base with records through 1980. These characteristics include annual and monthly flow statistics, duration of daily flow values, and the annual 7-day mean low flow at the 2-year and 10-year recurrence intervals. The 7-day, 10-year low-flow values are presented for 31 partial-record sites and the procedures used to determine the hydrologic characteristics of the basin are summarized. Basin characteristics representing 14 commonly used indices to estimate various streamflows are presented for the six gaged streams in the Blackstone River basin. This gazetteer will aid in the planning and siting of water-resources-related activities and will provide a common data base for governmental agencies and the engineering and planning communities. (USGS)

Would a new definition and classification of nocturia and nocturnal polyuria improve our management of patients? ICI-RS 2014.

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Bosch, J L H Ruud; Everaert, Karel; Weiss, Jeffrey P; Hashim, Hashim; Rahnama'i, M Sajjad; Goessaert, An-Sofie; Aizen, Joshua

2016-02-01

The following is a report of the proceedings of the Nocturia Think Tank sessions of the annual International Consultation on Incontinence-Research Society, which took place September 22-24, 2014 in Bristol, UK. The report is organized into sections pertaining to the main topic of discussion focussing on the question as to whether a new definition and classification of nocturia and nocturnal polyuria would improve the outcome of management in our patients. First, discussions identified theoretical and practical shortcomings of current definitions. Secondly, the utility of several nocturnal polyuria definitions was tested in a real life population in relation to the symptom nocturia, in order to display weaknesses of these definitions. Thirdly, we explored in a clinical population the utility of bladder diary based parameters by asking the question: when nocturia improves, which of these parameters improve most? Based on the above explorations the Think Tank summarized elements of the current definitions that need reconsideration and suggests proposals for further research to reach more practical and more clinically meaningful definitions. © 2015 Wiley Periodicals, Inc.

Writing from the Margins of Myself

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Luci Gorell Barnes

2014-02-01

Full Text Available In my doctoral studies at the University of Bristol, I took part in an experimental process of free writing, and my paper begins with the short story that emerged from this. During the taught unit we discussed ethical dilemmas that might arise from writing as inquiry, and in the commentary that follows my story, I reflect on how this practice requires an awareness of care for self and others. I describe my process, and discuss how it allowed me to transcend my dominant voice and restructure some of my ideas about what I study. I propose that by writing fiction I was able to consider complex issues in a way that opened up multiple meanings for me, and offered different views into social experience. I was guided by my practice as a visual artist and inspired by the writings of Ursula Le Guin (2004, Miller Mair (1989, and Ronald Pelias (2004, who encouraged me to listen in an empathic way, and write from the heart.

An update on the use of Atripla® in the treatment of HIV in the United States

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Michael A Horberg

2010-06-01

Full Text Available Michael A Horberg1, Daniel B Klein21HIV Interregional Initiative, Kaiser Permanente, Oakland, California, USA; 2Department of Infectious Diseases, Kaiser Permanente Hayward Medical Center, Hayward, California, USAAbstract: Atripla® (Gilead Sciences Inc, Foster City, CA, USA and Bristol-Myers Squibb, New York City, NY, USA is a coformulated single pill composed of efavirenz, emtricitabine, and tenofovir disoproxil, intended as a once-daily potent combination antiretroviral therapeutic agent. Its efficacy is equivalent to the 3 component drugs taken in a combination as single medications. The coformulated antiretroviral regimen can be quite effective in patients whose human immunodeficiency virus is sensitive to all 3 components of Atripla. However, women at risk of pregnancy, already pregnant, or nursing mothers should not take Atripla, due to the teratogenic potential of the efavirenz moiety. Adverse effects are similar to those seen with the constituent medications, including potential central nervous system effects and renal toxicity. Since its US Food and Drug administration approval, prescriptions for Atripla have increased steadily.Keywords: tenofovir, efavirenz, emtricitabine, antiretroviral therapy

The role of nuclear emulsions in the institutionalization of research in experimental physics in Brazil

International Nuclear Information System (INIS)

Vieira, Cassio Leite; Videira, Antonio A.P.

2011-01-01

In this paper, we describe and analyze the introduction and the use of the nuclear emulsions technique in Brazil. Even though consistent researches in cosmic ray physics had been done since the forties of the last century in this country, physicists here only began using this technique after Cesar Lattes' works in Bristol (England) and Berkeley (US). Despite being the implantation of the technique in this country posterior to the origin of the method itself dated from late 1900s, Brazilian scientists were quickly familiarized with it and adopted it not only in cosmic rays, but also in particle physics and nuclear physics, employing it until recently. In our work, we will be concerned with the reasons of this longevity. In other words, why were the nuclear emulsions technique employed for so many years in Brazil, even after its vanishing in physics researches centers in the world? We advance here that the answer to this question involves the institutionalization of science in Brazil mainly physics and economical, social, and geographic reasons. (author)

The role of nuclear emulsions in the institutionalization of research in experimental physics in Brazil; O papel das emulsoes nucleares na institucionalizacao da pesquisa em fisica experimental no Brasil

Energy Technology Data Exchange (ETDEWEB)

Vieira, Cassio Leite [Instituto Ciencia Hoje, Rio de Janeiro, RJ (Brazil); Videira, Antonio A.P. [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil); Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Brasilia, DF (Brazil)

2011-07-01

In this paper, we describe and analyze the introduction and the use of the nuclear emulsions technique in Brazil. Even though consistent researches in cosmic ray physics had been done since the forties of the last century in this country, physicists here only began using this technique after Cesar Lattes' works in Bristol (England) and Berkeley (US). Despite being the implantation of the technique in this country posterior to the origin of the method itself dated from late 1900s, Brazilian scientists were quickly familiarized with it and adopted it not only in cosmic rays, but also in particle physics and nuclear physics, employing it until recently. In our work, we will be concerned with the reasons of this longevity. In other words, why were the nuclear emulsions technique employed for so many years in Brazil, even after its vanishing in physics researches centers in the world? We advance here that the answer to this question involves the institutionalization of science in Brazil mainly physics and economical, social, and geographic reasons. (author)

Flatfish recruitment response to decadal climatic variability and ocean conditions in the eastern Bering Sea

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Wilderbuer, T. K.; Hollowed, A. B.; Ingraham, W. J.; Spencer, P. D.; Conners, M. E.; Bond, N. A.; Walters, G. E.

2002-10-01

This paper provides a retrospective analysis of the relationship of physical oceanography and biology and recruitment of three Eastern Bering Sea flatfish stocks: flathead sole ( Hippoglossoides elassodon), northern rock sole ( Lepidopsetta polyxystra), and arrowtooth flounder ( Atheresthes stomias) for the period 1978-1996. Temporal trends in flatfish production in the Eastern Bering Sea are consistent with the hypothesis that decadal scale climate variability influences marine survival during the early life history period. Density-dependence (spawning stock size) is statistically significant in a Ricker model of flatfish recruitment, which includes environmental terms. Wind-driven advection of flatfish larvae to favorable nursery grounds was also found to coincide with years of above-average recruitment through the use of an ocean surface current simulation model (OSCURS). Ocean forcing of Bristol Bay surface waters during springtime was mostly shoreward (eastward) during the 1980s and seaward (westerly) during the 1990s, corresponding with periods of good and poor recruitment. Distance from shore and water depth at the endpoint of 90-day drift periods (estimated time of settlement) were also found to correspond with flatfish productivity.

Impact of the implementation of a well-designed electronic laboratory notebook on bioanalytical laboratory function.

Science.gov (United States)

Zeng, Jianing; Hillman, Mark; Arnold, Mark

2011-07-01

This paper shares experiences of the Bristol-Myers Squibb Company during the design, validation and implementation of an electronic laboratory notebook (ELN) into the GLP/regulated bioanalytical analysis area, as well as addresses the impact on bioanalytical laboratory functions with the implementation of the electronic notebook. Some of the key points covered are: knowledge management - the project-based electronic notebook takes full advantage of the available technology that focuses on data organization and sharing so that scientific data generated by individual scientists became department knowledge; bioanalytical workflows in the ELN - the custom-built workflows that include data entry templates, validated calculation processes, integration with laboratory information management systems/laboratory instruments, and reporting capability improve the data quality and overall workflow efficiency; regulatory compliance - carefully designed notebook reviewing processes, cross referencing of distributed information, audit trail and software validation reduce compliance risks. By taking into consideration both data generation and project documentation needs, a well-designed ELN can deliver significant improvements in laboratory efficiency, work productivity, and regulatory compliance.

A Comparison of FDM Structural Layouts and Implementation of an Open-Source Arm-Based System

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Pollard David

2018-01-01

Full Text Available Fused Deposition Modelling (FDM is a manufacturing process to build components in a layer-by-layer approach through extrusion of polymers from a movable nozzle, allowing for significantly higher degrees of complexity over machined parts. Current FDM systems typically use actuation provided through a gantry or delta structural layout, operating through depositing successive planar layers in a 2.5D process; it has been shown in numerous studies the bonding between layers has significantly lower strength than the homogeneous material or in-plane properties - an issue which can be mitigated through the deposition of curved layers. This paper compares four differing structural layouts of FDM systems (gantry, delta, Stewart Platform, and arm-based to identify the key advantages of an arm-based method as the increased workspace and manipulability enabling “Additive Finalisation” of components, and suitability for curved layer FDM. Details are then presented of the open-source implementation and evaluation of a 6 degree-of-freedom arm-based FDM printer at the University of Bristol.

Breaking bad news revisited: the push for negotiated disclosure and changing practice implications.

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Arber, Anne; Gallagher, Ann

2003-04-01

This article revisits the ethical, legal, professional and emotional issues involved with disclosing bad news. The authors examine the push for disclosure that has come from a number of quarters in the UK, including ethical and legal challenges, in particular the Bristol Royal Inquiry Report, professional codes of conduct, health policy and the expectations of the public. The contribution of nurses to breaking bad news is not widely discussed in the literature. With the development of new nursing roles and evidence-based practice it is timely to consider the role of nurses in this process. The article highlights some limitations with current guidelines for breaking bad news, in particular, that these guidelines tend to be constructed from a professional standpoint and lack patient-centred evidence. The issue of emotional labour and how it relates to giving bad news is discussed with respect to professional staff and patients. The article concludes by raising some practice implications, including: the importance of context and continuity; the significance of information and support; the desirable qualities of the professional; and issues to consider in determining patient preferences.

Applying a new understanding of supergene REE deposit formation to global exploration initiatives for environmentally sustainable resources

Science.gov (United States)

Hardy, Liam; Smith, Martin; Hood, Leo; Heller, Shaun; Faltyn, Rowan; Blum, Astrid; Bamberger, Axel

2017-04-01

). Rare earth elements: A review of production, processing, recycling and associated environmental issues; EPA600/R-12/572. United States Environmental Protection Agency. Hardy, L. (2016). A novel mechanism for the formation of REE ion-adsorption deposits. Presented to: MDSG Winter Meeting, Bristol University, 20/12/16. Jenkins, R. (1979). The Road to Alto: An account of peasants, capitalists and their soil in the mountains of Southern Portugal. London: Pluto, ISBN: 0861040767. Marquis, E. (2016). Ion Adsorption-Type REE Deposit associated with the Ambohimirahavavy Alkaline Complex: Potential Controls on Mineralisation. Presented to: MDSG Winter Meeting, Bristol University, 20/12/16.

Investigating effective support mounts for fans during display by exploring new technologies

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Sarah Bright

2012-06-01

Full Text Available Blaise Castle House Museum in Bristol (UK houses a large and impressive collection of 130 European fans ranging from 1700-1950 with 60 brisé and 70 other fans in a generally good condition.  This research project explored how to best support this sort of collection by using 3D fabrication technology to create bespoke mounts.  At present making mounts for fans is complex and time consuming due to the layering and structure of fans, and the need for accuracy if the mount is to support the fan sufficiently.  This project explored how creating a digital 3D image of a fan could enable 3D fabrication technologies to be used to produce an exact ‘imprint’ of the object ensuring that all areas were supported, allowing a more suitable fan display to be created.  This paper outlines the process of exploring the principles of creating mounts for fans; narrates the process of selecting suitable objects for display, and the process of creating a digitally-produced fan mount.Blaise Castle House Museum à Bristol (Royaume-Uni abrite une importante et impressionnante collection de 130 éventails européens, datés de 1700 à 1950, dont 60 brisés et 70 autres dans un bon état général. Ce projet de recherche consiste à présenter au mieux ce type de collection en utilisant la technologie de fabrication 3D pour créer des supports sur mesure. À l'heure actuelle la conception de présentoirs est complexe et prend du temps, en raison de la structure des objets, et d’un besoin extrême de précision lorsque l’objectif est d’apporter un soutien aux différentes composantes des éventails. Ce projet explore donc comment la création d'une image numérique 3D d'un éventail pourrait permettre à des technologies de fabrication en 3D d’être utilisées pour produire une exacte «empreinte» de l'objet et veiller à ce que toutes les composantes soient supportées, permettant ainsi de créer le présentoir. Ce document décrit le processus d

Crew of Hubble Space Telescope servicing mission visits Europe

Science.gov (United States)

1994-01-01

The Hubble Space telescope servicing mission in December (STS-61) was a great success and the fully refurbished orbiting telescope produced absolutely remarkable first results just two weeks ago. The 7-member crew who carried out the mission will soon be in Europe to share their experience with the Press, ESA space specialists and the European space community. Public conferences will also be held in Switzerland, the home country of ESA astronaut Claude Nicollier. The visit of the STS-61 crew is scheduled as follows: Friday 11 February, 1994 - ESA Paris, France Presentation and Press Conference Location: ESA, 8/10 Rue Mario Nikis, 75015 Paris time: 16:00 hrs - 17:30 hrs contact: ESA, Public Relations Office Tel. (+33) 1 42 73 71 55 Fax. (+33) 1 42 73 76 90 Monday 14 February, 1994 - British Aerospace, Bristol, United Kingdom Presentation and Press Conference Location: British Aerospace, FPC 333, Filton, Bristol BS12 7QW time: 10:00 hrs - 12:00 hrs contact: BAe, Public Relations Tel. (+44) 272 36 33 69 Tel. (+44) 272 36 33 68 Tuesday 15 February, 1994 - ESA/ESTEC, Noordwijk, the Netherlands Presentation and Press Conference Location: Noordwijk Space Expo, Keplerlaan 3, 2201 AZ Noordwijk, the Netherlands time: 09:30 hrs - 12:00 hrs contact: ESTEC Public Relations Office Tel. (+31) 1719 8 3006 Fax. (+31) 1719 17 400 Wednesday 16 February, 1944 - ESO, Garching - Munich, Germany Presentation and Press Conference Location: European Southern Observatory, Karl- Schwarzschild-Str. 2, 85748 Garching -Munich, Germany time: to be decided contact: ESO Information Service Tel. (+49) 89 32 006 276 Fax. (+49) 89 320 23 62 Thursday 17 February, 1994 - Bern, Switzerland a. Presentation and Press Conference Location: Hotel Bern, Zeughausgasse 9, 3001 Bern, Switzerland time: 09:30 hrs contact: Press & Information Service of the Federal Dept. for Education & Sciences Tel. (+41) 31 322 80 34 Fax. (+41) 31 312 30 15 b. Public conference Location: University of Bern, Institute of Physics

Health-related quality of life, visual function and treatment satisfaction following intravitreal dexamethasone implant for diabetic macular edema

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Ramu J

2017-03-01

Full Text Available Jayashree Ramu,1 Irini Chatziralli,1 Yit Yang,2 Geeta Menon,3 Clare Bailey,4 Michael Eckstein,5 Phil Hykin,1 Sobha Sivaprasad1 On behalf of the OZDRY Study Group 1NIHR Moorfields Biomedical Research Centre, London, 2The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, 3Frimley Health NHS Foundation Trust, Surrey, 4Bristol Eye Hospital, Bristol, 5Brighton and Sussex University Hospital, Brighton, UK Purpose: The aim of this study was to explore and describe quantitatively patient-reported outcome measures (PROMs, ie, health-related quality of life (QoL, visual function and treatment satisfaction, in patients with diabetic macular edema (DME receiving two different regimens of Ozurdex (intravitreal dexamethasone implant. Methods: In this multicenter, prospective study, 100 patients with center-involving refractory DME were randomized 1:1 to either five monthly fixed dosing or optical coherence tomography (OCT-guided pro re nata (PRN regimen of dexamethasone intravitreal implant therapy. The primary outcome was the difference between arms in change in PROMs and health-related QoL from baseline to 12 months, as measured by the Retinopathy-Dependent Quality of Life (RetDQoL questionnaire, Visual Function Questionnaire-25 (VFQ-25 and Retinopathy Treatment Satisfaction Questionnaire (RetTSQ. Results: There was no statistically significant difference in the RetDQoL score and VFQ-25 score at month 12 compared to those at baseline, whereas the total mean RetTSQ score increased significantly at the exit visit. The two treatment arms did not differ significantly regarding the change in PROMs and health-related QoL questionnaires. Logistic regression analysis showed that visual acuity (VA of ≥55 letters, central foveal thickness <300 µm and macular volume <9.2 mm3 at the exit visit (month 12 predicted a higher change in RetTSQ. Conclusion: This study showed that there is a statistically significant improvement in treatment satisfaction, as

Professional Practice as an Element of Taxonomy - A Case of IT Students at the Polytechnic of Rijeka

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Miro Francic

2010-03-01

Full Text Available There are two reasons for a formal review of the formal forms of education: the development speed of data-communication technologies and the increasing willingness of business entities to apply the same in a very strong competitive battle for dominance at the market. Although not only reason they are a sufficient challenge for educational institutions to adjust their curricula especially when they will help to better prepare their students for the labour market. Professional practice as a form of the highest levels of taxonomies, observed by Bloom’s scale, should be used for evaluating student performance, but also for evaluating the quality and marketing of all available programs. This paper presents the experience of professional studies of computer science at Polytechnic of Rijeka acquired through the organization of professional practice in those businesses, which represent a potential place of work after the completion of studies. Conducted research, together with the acquired experience can be a framework for any changes or modifications to curriculum and teaching methods. Respondents pattern for the two main groups: business owners, which basic business is providing IT services and those which use computer to support base of operations. What do respondents who supervise professional practice think about the readiness of graduates for inclusion in their business, which competencies are expected of potential candidates for employment and what are their proposals for changing the program?

International Biophysics Congress (8th) Held in Bristol, United Kingdom on 29 July-4 August 1984. Final Programme and Book of Abstracts

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1986-02-03

OCPA, t b-Amine, epirepbire anc :ate&in. r n.-l fubrlnQrar, lMihZ-ko --0 % clottec-t) were to4es Toc to. te-npetdtu-e (]!C20.350 K) trodSea...Liquidos y Sistemas Bioldgicon und Phys. Biochemie, Universitlt Regensburg (IFLYSIB), 1900 La Plata, Argentina. "’Departmnt X-Irradiation of single...Jescribed bt Creighton (3. Mol :Xti. 129: 235) has been ased ET-oo tb.-.ji-B0S3 ZUrich, Switzerland, to screen ritarit, forr: -7 yeait Zy- toc :6rC c Cn a

Effects of ocean acidification on fishery yields and profits of red king crab in Bristol Bay from model studies (NCEI Accession 0127395)

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National Oceanic and Atmospheric Administration, Department of Commerce — This archival package contains model output data that were collected to examine the impact of ocean acidification on fishery yields and profits of red king crab in...

Carbetocin versus oxytocin for the prevention of postpartum haemorrhage following caesarean section: the results of a double-blind randomised trial.

Science.gov (United States)

Attilakos, G; Psaroudakis, D; Ash, J; Buchanan, R; Winter, C; Donald, F; Hunt, L P; Draycott, T

2010-07-01

To compare the effectiveness of carbetocin and oxytocin when they are administered after caesarean section for prevention of postpartum haemorrhage (PPH). Double-blind randomised single centre study (1:1 ratio). Teaching hospital in Bristol, UK with 6000 deliveries per annum. Women at term undergoing elective or emergency caesarean section under regional anaesthesia, excluding women with placenta praevia, multiple gestation and placental abruption. Women were randomised to receive either carbetocin 100 microg or oxytocin 5 IU intravenously after the delivery of the baby. Perioperative care was otherwise normal and use of additional oxytocics was at the discretion of the operating obstetrician. Analysis was by intention to treat. The proportion of women in each arm of the trial that needed additional pharmacological oxytocic interventions. Significantly more women needed additional oxytocics in the oxytocin group (45.5% versus 33.5%, Relative risk 0.74, 95% CI 0.57-0.95). The majority of women had oxytocin infusions. There were no significant differences in the secondary outcomes, including major PPH, blood transfusions and fall in haemoglobin. Carbetocin is associated with a reduced use of additional oxytocics. It is unclear whether this may reduce rates of PPH and blood transfusions.

Do we need to know more about the effects of hormones on lower urinary tract dysfunction? ICI-RS 2014.

Science.gov (United States)

Hanna-Mitchell, Ann T; Robinson, Dudley; Cardozo, Linda; Everaert, Karel; Petkov, Georgi V

2016-02-01

This review article reflects the presentations and subsequent discussions during a think tank at the 5th International Consultation on Incontinence Research Society's annual meeting, held in Bristol, UK (September 22-24, 2014). It reviews the current state of knowledge on the role of hormones in lower urinary tract dysfunction (LUTD) and overactive bladder (OAB) and in particular: highlights some specific basic research findings from discussion participants; reviews future research topics; and discusses potential new therapeutic opportunities for LUTD and OAB. The role of the large conductance voltage- and Ca(2+) -activated K(+) (BK) channels, as novel therapeutic targets for OAB was discussed, in particular as recent studies on human detrusor smooth muscle suggest that estradiol exerts a direct non-genomic activation of the BK channels. Recent developments on the roles of sex hormones on diuresis, as well as the roles of melatonin and vitamin D on LUTD were also discussed. It was concluded that further basic science and translational studies are needed to better understand hormonal regulatory mechanisms of the lower urinary tract and the implications for novel treatment options for LUTD and OAB. © 2016 Wiley Periodicals, Inc.

Should Undergraduate Lectures be Compulsory? The Views of Dental and Medical Students from a UK University

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Alaa Daud

2017-03-01

Full Text Available Formal lectures have been a traditional part of medical and dental education, but there is debate as to their compulsory status. This study was designed to explore dental and medical students’ views on compulsory lectures and the use of Video-Recorded Lectures (VRL. A cross-sectional study of University of Bristol students in Years 2 to 4 was conducted using an online questionnaire. The majority of both dental (76% and medical (66% students felt lectures should be non-compulsory. The most common learning resources used by both dental and medical students were live lectures, lecture handouts and VRL. The majority of both dental (84% and medical (88% students used VRL. Most students attended lectures all of the time both before and after the introduction of VRL, even though most dental and medical students believe lectures should be non-compulsory. VRL is a popular learning resource. These findings tie-in with General Dental Council and General Medical Council recommendations that encourage self-directed learning. Dental and Medical schools should offer a range of learning resources and make use of current technology, including the use of VRL.

Geographically distributed hybrid testing & collaboration between geotechnical centrifuge and structures laboratories

Science.gov (United States)

Ojaghi, Mobin; Martínez, Ignacio Lamata; Dietz, Matt S.; Williams, Martin S.; Blakeborough, Anthony; Crewe, Adam J.; Taylor, Colin A.; Madabhushi, S. P. Gopal; Haigh, Stuart K.

2018-01-01

Distributed Hybrid Testing (DHT) is an experimental technique designed to capitalise on advances in modern networking infrastructure to overcome traditional laboratory capacity limitations. By coupling the heterogeneous test apparatus and computational resources of geographically distributed laboratories, DHT provides the means to take on complex, multi-disciplinary challenges with new forms of communication and collaboration. To introduce the opportunity and practicability afforded by DHT, here an exemplar multi-site test is addressed in which a dedicated fibre network and suite of custom software is used to connect the geotechnical centrifuge at the University of Cambridge with a variety of structural dynamics loading apparatus at the University of Oxford and the University of Bristol. While centrifuge time-scaling prevents real-time rates of loading in this test, such experiments may be used to gain valuable insights into physical phenomena, test procedure and accuracy. These and other related experiments have led to the development of the real-time DHT technique and the creation of a flexible framework that aims to facilitate future distributed tests within the UK and beyond. As a further example, a real-time DHT experiment between structural labs using this framework for testing across the Internet is also presented.

Absent Histories and Absent Images: Photographs, Museums and the Colonial Past

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Elizabeth Edwards

2015-04-01

Full Text Available Based on research in a range of UK museums, this paper explores the visibility and invisibility of the photographic legacy of colonial relations and the representation of the colonial past in museum galleries. It explores the conditions of the ‘invisibility’ and ‘disavowal’ of the colonial past in the historical narrative developed by museums, and the anxieties that cluster around such narratives in a postcolonial and multicultural society. The paper argues that the photographic legacy of the colonial past offers a way into those histories, but it is one that can only be realized through the critical engagement with photographs themselves and the work they might be made to do in museums. As an example, it examines the active and complex role of photographs played in the galleries of the British Empire and Commonwealth Museum, Bristol. It concludes that the failure of museums to integrate colonial pasts into their narratives has worked against the wider liberal agendas to which museums subscribe, and that photographic invisibility is both a symptom of and metaphor for the ‘invisibility’ of the colonial past.

Using the WIMS-DIREN bigroup and multigroup methodology for Cernavoda Unit 1 and Unit 2 adjuster rods comparative reactivity calculations at Phase B commissioning

International Nuclear Information System (INIS)

Prodea, Iosif; Patrulescu, Ilie; Rizoiu, Andrei; Danila, Nicolae; Prisecaru, Ilie

2007-01-01

One of the most important CANDU reactor regulation system is the Adjuster Rods System (ADJ). The individual and bank calibration and performance evaluation of this system is carried out during the Phase B commissioning. The ADJ rods are grouped into seven banks based on full power reactivity control requirements. The Cernavoda Unit 2 adjuster rods characteristics were designed more than twenty years ago at INR Pitesti in the end of a fruitful collaboration between INR Pitesti (as designer) and Bristol Aerospace Limited (as manufacturer). In 1996, during the Phase B commissioning tests only AECL diffusion and Westcott approximation methodology was used. An alternative integral transport and high-modes diffusion approximation methodology was developed in INR Pitesti during the last years. As a result, the first collision probability code PIJXYZ was created and developed to carry out the supercell calculations as well as the code DIREN for 3D diffusion-based core simulations. The aim of this work was to evaluate comparatively the two adjuster rods systems (from Unit 1 and 2) in commissioning conditions. The concrete results will consist of individual, bank and total adjuster rods reactivity estimations with an emphasis on the differences and similarities between them. (authors)

Framework for Understanding LENR Processes, Using Ordinary Condensed Matter Physics

Science.gov (United States)

Chubb, Scott

2005-03-01

As I have emphasizedootnotetextS.R. Chubb, Proc. ICCF10 (in press). Also, http://www.lenr-canr.org/acrobat/ChubbSRnutsandbol.pdf http://www.lenr-canr.org/acrobat/ChubbSRnutsandbol.pdf, S.R. Chubb, Trans. Amer. Nuc. Soc. 88 , 618 (2003)., in discussions of Low Energy Nuclear Reactions(LENRs), mainstream many-body physics ideas have been largely ignored. A key point is that in condensed matter, delocalized, wave-like effects can allow large amounts of momentum to be transferred instantly to distant locations, without any particular particle (or particles) acquiring high velocity through a Broken Gauge Symmetry. Explicit features in the electronic structure explain how this can occur^1 in finite size PdD crystals, with real boundaries. The essential physics^1 can be related to standard many-body techniquesootnotetextBurke,P.G. and K.A. Berrington, Atomic and Molecular Processes:an R matrix Approach (Bristol: IOP Publishing, 1993).. In the paper, I examine this relationship, the relationship of the theory^1 to other LENR theories, and the importance of certain features (for example, boundaries^1) that are not included in the other LENR theories.

Re-thinking accountability: trust versus confidence in medical practice.

Science.gov (United States)

Checkland, K; Marshall, M; Harrison, S

2004-04-01

In seeking to prevent a reoccurrence of scandals such as that involving cardiac surgery in Bristol, the UK government has adopted a model of regulation that uses rules and surveillance as a way of both improving the quality of care delivered and increasing confidence in healthcare institutions. However, this approach may actually act to reduce confidence and trust while also reducing the moral motivation of practitioners. Accountability in health care is discussed, and it is suggested that openness about the difficult dilemmas that arise when practitioners have a duty to be accountable to more than one audience may be an alternative means of restoring trust. A greater emphasis on the sharing of information between individual health professionals and their patients would increase trust and would allow patients to hold their doctors to account for the quality of care they receive. Concentrating more on developing trust by the sharing of information and less on the futile search for complete confidence in systems and rules may improve the quality of care delivered while also nurturing the moral motivation of professionals upon which the delivery of high quality health care depends.

Cognitive Profiles on the Severe Impairment Battery Are Similar in Alzheimer Disease and Down Syndrome With Dementia.

Science.gov (United States)

Dick, Malcolm B; Doran, Eric; Phelan, Michael; Lott, Ira T

2016-01-01

Previous research has revealed similarities in the neuropathology, clinical presentation, and risk factors between persons with Alzheimer disease from the general population (GP-AD) and those with Down syndrome (DS-AD). Less is known, however, about the extent of similarities and differences in the cognitive profiles of these 2 populations. Fifty-one moderate to severely demented GP-AD and 59 DS-AD individuals participated in this study which compared the cognitive profiles of these 2 populations on the Severe Impairment Battery (SIB), controlling for sex as well as level of functional ability using a modified version of the Bristol Activities of Daily Living Scale. Overall, the neuropsychological profiles of the higher-functioning individuals within the DS-AD and advanced GP-AD groups, as represented by mean difference scores on the SIB as a whole and across the 9 separate cognitive domains, were very similar to one another after adjusting for sex and functional impairment. To our knowledge, this is the first study to directly compare the cognitive profiles of these 2 populations on the SIB. Findings suggest that the underlying dementia in GP-AD and DS-AD may have corresponding and parallel effects on cognition.

The Statistical Fragmentation Theory of N. F. Mott

Science.gov (United States)

Grady, Dennis

2004-07-01

For a brief period during the height of World War II, Neville F. Mott left his position at the University of Bristol and headed up a concerted theoretical effort at Fort Halstead, UK, to investigate the operational science of weapons and armor technology. The seminal achievements resulting from the efforts of the participating scientists are extraordinary and have provided the basis for much of the continuing research in this field over the intervening six decades. N. F. Mott chose to study the phenomenon of the explosive-driven fragmentation of exploding shell cases. The approaches pursued by Mott are documented in several interim reports and open literature publications and offer a fascinating look into the insightful thinking and scientific methods of one of the preeminent physicists of the last century. This presentation offers a perspective into the several theoretical approaches pursued by Mott. In particular, the hallmark relation for the representation of exploding munitions fragmentation data to the present day is the Mott distribution. The efforts of Mott leading to this distribution are explored and a judgment is offered as to whether Mott himself would use this distribution today.

Relevance of 19th century continuous tone photomechanical printing techniques to digitally generated imagery

Science.gov (United States)

Hoskins, Stephen; Thirkell, Paul

2003-01-01

Collotype and Woodburytype are late 19th early 20th century continuous tone methods of reproducing photography in print, which do not have an underlying dot structure. The aesthetic and tactile qualities produced by these methods at their best, have never been surpassed. Woodburytype is the only photomechanical print process using a printing matrix and ink, that is capable of rendering true continuous tone; it also has the characteristic of rendering a photographic image by mapping a three-dimensional surface topography. Collotype"s absence of an underlying dot structure enables an image to be printed in as many colours as desired without creating any form of interference structure. Research at the Centre for Fine Print Research, UWE Bristol aims to recreate these processes for artists and photographers and assess their potential to create a digitally generated image printed in full colour and continuous tone that will not fade or deteriorate. Through this research the Centre seeks to provide a context in which the development of current four-colour CMYK printing may be viewed as an expedient rather than a logical route for the development of colour printing within the framework of digitally generated hard copy paper output.

Does the increased rate of schizophrenia diagnosis in African-Caribbean men in the UK shown by the AESOP study reflect cultural bias in healthcare?

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Ngaage, Millie; Agius, Mark

2016-09-01

The UK-based AESOP study conducted over a two-year period in three UK sites simultaneously (London, Nottingham, and Bristol), is the largest study to date to conduct a first contact case-control study of psychosis. The study found that rates of schizophrenia were markedly elevated in both African-Caribbean and Black African people, in both sexes and across all age groups. English language literature published up to 2016 was searched. The initial search included: PubMed, The Cochrane Library, and Web of Science. A second search was conducted using Medical Subject Headings (MeSH) and keywords. Studies selected for retrieval were assessed by two independent reviewers. The search yielded eight results, all of which supported the conclusion of an increased incidence of schizophrenia in Black African and Black Caribbean population in the AESOP study. England is a multicultural landscape; multiplicity of cultures makes diagnosis difficult. The lessons we must learn from the AESOP study is the need for transcultural training and the removal of blinding to ethnicity when a large epidemiological study is conducted - psychiatrists need to be cognisant of cultures and aware of the context of symptoms.

Lower urinary tract symptoms and metabolic disorders: ICI-RS 2014.

Science.gov (United States)

Denys, Marie-Astrid; Anding, Ralf; Tubaro, Andrea; Abrams, Paul; Everaert, Karel

2016-02-01

To investigate the link between lower urinary tract symptoms (LUTS) and metabolic disorders. This report results from presentations and subsequent discussions about LUTS and metabolic disorders at the International Consultation on Incontinence Research Society (ICI-RS) in Bristol, 2014. There are common pathophysiological determinants for the onset of LUTS and the metabolic syndrome (MetS). Both conditions are multifactorial, related to disorders in circadian rhythms and share common risk factors. As in men with erectile dysfunction, these potentially modifiable lifestyle factors may be novel targets to prevent and treat LUTS. The link between LUTS and metabolic disorders is discussed by using sleep, urine production and bladder function as underlying mechanisms that need to be further explored during future research. Recent findings indicate a bidirectional relationship between LUTS and the MetS. Future research has to explore underlying mechanisms to explain this relationship, in order to develop new preventive and therapeutic recommendations, such as weight loss and increasing physical activity. The second stage is to determine the effect of these new treatment approaches on the severity of LUTS and each of the components of the MetS. © 2016 Wiley Periodicals, Inc.

Identifying Underlying Emotional Instability and Utilizing a Combined Intervention in the Treatment of Childhood Constipation and Encopresis-A Case Report.

Science.gov (United States)

Davis, Jamie L

2016-06-01

Childhood constipation is a common ailment that in certain cases can lead to encopresis or fecal incontinence. The literature suggests that standard care varies in effectiveness, especially in the long term. Fecal incontinence can lead to frustration, guilt, and shame for both the child and family and has untold long-term psychological and physical consequences. To address alternative treatment options for pediatric constipation and encopresis by using acupuncture and Chinese medicine. Patient and Setting: This is a case study of a 6-year-old girl seen in a private practice acupuncture clinic in the northwestern United States. Treatment involved acupuncture, massage, and Chinese herbal medicine. The patient in this study began to have regular bowel movements on her own, from a type 5 on the modified Bristol Stool Form Scale for Children to a type 3, with no laxative use and few to no fecal accidents. Emotional stability and support seem to play an important role in pediatric constipation and encopresis. Acupuncture may be an effective treatment option in the integrative care model to address both the emotional and physical components of childhood constipation.

Managing novel reproductive injuries in the law of tort: the curious case of destroyed sperm.

Science.gov (United States)

Priaulx, Nicolette

2010-03-01

In view of developments in reproductive medicine, clinical mishaps in this domain are beginning to give rise to 'injuries' not easily accommodated within the English law of negligence. While 'personal injury' is typically understood as manifesting a deleterious 'physical' dimension, cases involving the negligent destruction of cryopreserved sperm, as recently litigated in Yearworth & Ors v Bristol NNN Trust (2009), and other media reported mishaps in fertility treatment do not straightforwardly possess this quality. Without modification, the traditional tortious conception of 'personal injury' in English law will not be able to address novel claims. Critically, however, nor do alternative modes of redress seem to offer ease of application. Focusing upon the controversial Yearworth case and exploring what is seen as an unpromising framing of loss, the note argues that there is now an urgent need to rethink what counts as 'personal injury'. Arguing for the formal recognition of'reproductive injury' as an independent head of damage in negligence, and illustrating the presence of judicial support for that approach, the comment suggests that in light of the difficult challenges that lie in the wake of Yearworth, such a development may be not only desirable but necessary.

Bowel habit reference values and abnormalities in young Iranian healthy adults.

Science.gov (United States)

Adibi, Peyman; Behzad, Ebrahim; Pirzadeh, Shahryar; Mohseni, Masood

2007-08-01

The purpose of this study was to estimate the prevalence of self-reported, ROME II-defined constipation and determine the average defecation frequency and stool types in the Iranian population. A self-reported questionnaire was distributed to 1045 participants, including items intended to identify the presence of ROME II-defined functional constipation and the dominant form of stool based on the Bristol Scale. The weekly mean bowel movement frequency in men and women was 12.5 +/- 7.3 and 13.8 +/- 8.0, respectively (p < 0.05). A total of 87.4% of participants had a stool frequency of between 3 and 21 times per week. The prevalence of functional constipation was 32.9%, whereas only 9.6% of participants reported themselves to be constipated (level of agreement kappa = 0.21, 95% confidence interval: 0.15 to 0.27). Soft or formed stool was reported in 75.7% of individuals. Functional constipation is common in the Iranian population, but its diagnosis could not rely on subjective patient complaints. Despite a higher average of bowel frequency, the previously reported normal range of defecation frequency can be applied for the Iranian population.

A heritable antiviral RNAi response limits Orsay virus infection in Caenorhabditis elegans N2.

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Mark G Sterken

Full Text Available Orsay virus (OrV is the first virus known to be able to complete a full infection cycle in the model nematode species Caenorhabditis elegans. OrV is transmitted horizontally and its infection is limited by antiviral RNA interference (RNAi. However, we have no insight into the kinetics of OrV replication in C. elegans. We developed an assay that infects worms in liquid, allowing precise monitoring of the infection. The assay revealed a dual role for the RNAi response in limiting Orsay virus infection in C. elegans. Firstly, it limits the progression of the initial infection at the step of recognition of dsRNA. Secondly, it provides an inherited protection against infection in the offspring. This establishes the heritable RNAi response as anti-viral mechanism during OrV infections in C. elegans. Our results further illustrate that the inheritance of the anti-viral response is important in controlling the infection in the canonical wild type Bristol N2. The OrV replication kinetics were established throughout the worm life-cycle, setting a standard for further quantitative assays with the OrV-C. elegans infection model.

Patterns in connectivity and retention of simulated Tanner crab (Chionoecetes bairdi) larvae in the eastern Bering Sea

Science.gov (United States)

Richar, Jonathan I.; Kruse, Gordon H.; Curchitser, Enrique; Hermann, Albert J.

2015-11-01

The eastern Bering Sea (EBS) population of Tanner crab (Chionoecetes bairdi) has exhibited high variability in recruitment to the commercially exploited stock since the late 1970s. Concurrently, apparent shifts in crab distribution have also been observed. Larval advection patterns and associated local retention offer a potential mechanism for these observations. The Regional Ocean Modeling System (ROMS) was used to simulate larval Tanner crab advection patterns over 1978-2004 based on larval hatching sites inferred from the distributions of reproductive females sampled during annual National Marine Fisheries Service trawl surveys. Connectivity among EBS subregions was examined by comparing start and end float locations after 60 days of simulated drift. High levels of retention (>50% of floats) were observed in the majority of source subregions, and contributed significantly to the total number of endpoints in each region. Patterns in advection and resultant interregional connectivity were variable, with strongest sustained connectivity occurring along shelf, within individual domains. Increased settlement potential in the outer domain and southern middle domain after 1990 is consistent with an observed geographic shift in fishery productivity. Apparent reliance of Bristol Bay on local larval retention validates recent spatial fishery management to conserve this area as a subpopulation.

Impacto socioeconómico do Instituto Politécnico da Guarda na economia local = Socio-economic impact of the Polytechnic of Guarda in the local economy

Directory of Open Access Journals (Sweden)

Maria Manuela Santos Natário

2014-06-01

Full Text Available As instituições de ensino superior e em particular os Institutos Politécnicos influenciam e beneficiam as regiões onde se inserem, sendo por vezes vitais para o seu desenvolvimento integrado (Arik e Nsiah, 2004; Pereira e Schneider, 2002; Johnson, Khaneja e Keagy, 2005. A maior parte destes institutos estão sedeados em regiões desfavorecidas e do interior com fragilidade do tecido económico e social e tornam-se fundamentais à sustentabilidade destes territórios, bem como, para manter a sua revitalização económica. Estas instituições assumem um papel central no desenvolvimento das regiões e na redução de assimetrias regionais, fundamentalmente pelo número adicional de empregos que geram e pelo acréscimo de rendimento proporcionado às regiões onde estão instaladas. Face a estas considerações, o objetivo deste trabalho é determinar o impacto socioeconómico do Instituto Politécnico da Guarda nos concelhos onde está inserido (Guarda e Seia. A análise incide sobre o lado da procura, utilizando para o efeito o modelo American Council on Education.Higher education institutions and in particular the polytechnic institutes influence and benefit the regions where they are implementation, and sometimes they are vital to their development (Arik and Nsiah, 2004; Pereira and Schneider, 2002; Johnson, Khaneja e Keagy, 2005. Most of these institutes are created in disadvantaged territories, characterized by fragility of the economic and social environment, and become fundamental to the sustainability of these territories, and to maintain its economic revitalization. These institutions play a central role in regional development and in the reduction of regional disparities, mainly due to additional job creation and the increase of income provided to regions where they are installed. Thus, the aim of this study is to estimate the socio-economic impact of the Polytechnic of Guarda in the municipalities of Guarda and Seia. The analysis

Training of solar energy applications in the Polytechnic School of Caceres; Docencia de las aplicaciones de la energia solar en la escuela politecnica de Caceres arquitectura termica

Energy Technology Data Exchange (ETDEWEB)

Tejeiro, C. Y.; Mendez, J. A. S.; Gutierrez, P. D. M.; Barrigon, J. M. M.

2004-07-01

In the Polytechnic School of Caceres, for the degree of Technical Architecture, the teaching of the installations of solar energy has been done by Final Projects. We have considered four basic points: 1st A diversified model of project, this means, a different building for each student, and a repeated typology of project. 2nd Teamwork, studying each student a part of the information, and explaining to the other. 3rd Internet as a forum and to obtain general information. 4th The Censolar course as calculus software and database in our laboratory. The result are 30 projects, some of them very completed, that resolve the general topic of the adaptation of the sport installations to be used with solar energy, besides of studying other topics as: maintenance of the installations, economic viability, integration in the landscape, etc. (Author)

ATTITUDES TOWARDS TUITION FEES PAYMENT IN TERTIARY EDUCATION: A SURVEY OF SUNYANI POLYTECHNIC MARKETING STUDENTS IN SUNYANI GHANA

Directory of Open Access Journals (Sweden)

Samuel Asuamah Yeboah

2012-01-01

Full Text Available The paper aims at contributing to knowledge in the area of educational finance by assessing student’s attitude towards tuition fees payment. The research is based on quantitative research design and a survey of the marketing students in Sunyani polytechnic that were selected using convenience sample method for a sample of 149. Data were analysed using percentages and one-ANOVA using the SPSS. The findings indicate that student’s knowledge on tuition fees and user fees are low. Respondents did not know that they do not pay tuition fees which are constitutional provision. Respondents consider it appropriate to contribute to the financing of their education but are not will to pay tuition. Parents of students should fund the education of their wards. Students face inadequate funding in their education and that result in worrying which affect their concentration while studying. Respondents are not willing to pay tuition fees and also the current user fees are high. Sources of funding students education are remittance from parents/friends/relative and scholarship. Those who are beneficiaries of the loan spend the amount mostly on course of study and on living expenses. This study should be replicated in other departments in the school and in other tertiary school to assess if these findings will be replicated. Since parents are the major financiers of education future study should target them to assess their attitude towards tuition fee payment.

Neutrons field in the neutronic measurements room of the Polytechnic University of Madrid; Campo de neutrones en la sala de medidas neutronicas de la Universidad Politecnica de Madrid

Energy Technology Data Exchange (ETDEWEB)

Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Calle Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas (Mexico); Gallego, E.; Lorente, A.; Rubio O, I. P., E-mail: hrvegacarrillo@yahoo.com.m [Universidad Politecnica de Madrid, Departamento de Ingenieria Nuclear, C/Jose Gutierrez Abascal No. 2, 28006 Madrid (Spain)

2010-09-15

Through of measurements and calculations of a Monte Carlo series has been characterized the neutronic field of the neutronic measurements room of Nuclear Engineering Department of the Polytechnic University of Madrid. The measurements were realized with the Bonner Spheres Spectrometer that allowed establish the spectra on the new stainless steel panel and at different distances measured regarding the source. The values of the speed of environmental equivalent dose were measured with an area monitor Bert hold Lb 6411. Through of Monte Carlo methods was built a detailed model of the room with the panel and the spectra were calculated and, with these the values of the environmental equivalent dose were obtained using the conversion coefficients of the ICRP 74 and the Bert hold Lb 6411 response. The calculated values were compared with those measured and was consistency among the results. (Author)

Teacher conceptions in the area of Nature Sciences about the construction of interdisciplinarity in Polytechnic Intermediate Education: the contribution of faculty expertise to reality in two schools in Northern Rio Grande do Sul

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Bruna Carminatti

2015-08-01

Full Text Available High School education in Rio Grande do Sul underwent reformulations with the proposal for Polytechnic Intermediate Education suggested by the State Education Office. Overall, this proposal arose from the demand for improvements in elementary education, where High School education is concerned, and was implemented along the years of 2012, 2013 and 2014. Among the desired improvements was the need to overcome content education through interdisciplinarity and an integrated curriculum. Taking such changes into consideration – which implied the creation of knowledge areas, curricular restructuring, changes to the means of evaluation and the planning and teaching methodology presumptions – this article aims to report the path and results from research that proposed to investigate the manner in which interdisciplinarity began being constructed by educators in the area of Nature Sciences from faculty expertise. The methodology employed was of ethnographic research, that allowed to gather a wealth of data and opinions from the individuals investigated, namely nine teachers from the Nature Sciences area that encompasses the subjects of chemistry, physics and biology, from two intermediate education public schools in Northern Rio Grande do Sul. Data interpretation was carried out under the perspective of Discursive Textual Analysis and allowed for the identification of both the hurdles that made interdisciplinary construction and action unfeasible, such as lack of time for planning, and possible alternatives to overcome such hurdles, among which faculty expertise. From the discussion of those results, it can be observed that the proposal for Polytechnic High School provided space for the construction of the interdisciplinary praxis as well as for reflecting on and awareness building of its need, making it feasible from theoretic-methodological (reoptions on the part of the faculty in the bias of their expertise as such.

Improving mathematical problem solving ability through problem-based learning and authentic assessment for the students of Bali State Polytechnic

Science.gov (United States)

Darma, I. K.

2018-01-01

This research is aimed at determining: 1) the differences of mathematical problem solving ability between the students facilitated with problem-based learning model and conventional learning model, 2) the differences of mathematical problem solving ability between the students facilitated with authentic and conventional assessment model, and 3) interaction effect between learning and assessment model on mathematical problem solving. The research was conducted in Bali State Polytechnic, using the 2x2 experiment factorial design. The samples of this research were 110 students. The data were collected using a theoretically and empirically-validated test. Instruments were validated by using Aiken’s approach of technique content validity and item analysis, and then analyzed using anova stylistic. The result of the analysis shows that the students facilitated with problem-based learning and authentic assessment models get the highest score average compared to the other students, both in the concept understanding and mathematical problem solving. The result of hypothesis test shows that, significantly: 1) there is difference of mathematical problem solving ability between the students facilitated with problem-based learning model and conventional learning model, 2) there is difference of mathematical problem solving ability between the students facilitated with authentic assessment model and conventional assessment model, and 3) there is interaction effect between learning model and assessment model on mathematical problem solving. In order to improve the effectiveness of mathematics learning, collaboration between problem-based learning model and authentic assessment model can be considered as one of learning models in class.

Developments in the Nuclear Safeguards and Security Engineering Degree Program at Tomsk Polytechnic University

International Nuclear Information System (INIS)

Boiko, Vladimir I.; Demyanyuk, Dmitry G.; Silaev, Maxim E.; Duncan, Cristen L.; Heinberg, Cynthia L.; Killinger, Mark H.; Goodey, Kent O.; Butler, Gilbert W.

2009-01-01

Over the last six years, Tomsk Polytechnic University (TPU) has developed a 5 1/2 year engineering degree program in the field of Material Protection Control and Accounting (MPC and A). In 2009 the first students graduated with this new degree. There were 25 job offers from nuclear fuel cycle enterprises of Russia and Kazakhstan for 17 graduates of the program. Due to the rather wide selection of workplaces, all graduates have obtained positions at nuclear enterprises. The program was developed within the Applied Physics and Engineering Department (APED). The laboratory and methodological base has been created taking into consideration the experience of the similar program at the Moscow Engineering Physics Institute (MEPhI). However, the TPU program has some distinguishing features such as the inclusion of special courses pertaining to fuel enrichment and reprocessing. During the last two years, three MPC and A laboratories have been established at APED. This was made possible due to several factors such as establishment of the State innovative educational program at TPU, assistance of the U.S. Department of Energy through Pacific Northwest National Laboratory and Los Alamos National Laboratory, and the financial support of the Swedish Radiation Safety Authority and some Russian private companies. All three of the MPC and A laboratories are part of the Innovative Educational Center 'Nuclear Technologies and Non-Proliferation,' which deals with many topics including research activities, development of new curricula for experts training and retraining, and training of master's students. In 2008, TPU developed a relationship with the International Atomic Energy Agency (IAEA), which was familiarized with APED's current resources and activities. The IAEA has shown interest in creation of a master's degree educational program in the field of nuclear security at TPU. A future objective is to acquaint nuclear fuel cycle enterprises with new APED capabilities and involve

Out of Our Heads! Four perspectives on the curation of an on-line exhibition of medically themed artwork by UK medical undergraduates

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Trevor Thompson

2010-11-01

Full Text Available The Medical School at Bristol University is noted for offering, and in some instances requiring, its students to work creatively with medical themes. Students, artists, educationalists and a web designer have worked to create an on-line exhibition of the resulting creative output. This can be viewed at www.outofourheads.net. This site is a themed repository of poetry, prose, drawings, paintings, cartoons, films, music, dance and rap. Most works come with commentaries that can be as illuminating as the works they describe. The site invites comment and welcomes new postings from anyone connected to medicine. As an alternative to the conventional pedagogical report, and in keeping with the subject matter, in this paper we tell the story of this unique educational enterprise through the narratives of four of its principle architects. The ‘Teacher's Tale’, the ‘Designer's Tale’, the ‘Curator's Tale’ and the ‘Artist's Tale’ offer different, personal, tellings of how the site came to be. Each tale contains hypertext links to notable works on the site some of which have become teaching resources within the institution. This paper is of relevance to anyone who seeks to explore and champion the human insights of this privileged community.

Effect of nutrients on the biodegradation of tributyltin (TBT) by alginate immobilized microalga, Chlorella vulgaris, in natural river water

Energy Technology Data Exchange (ETDEWEB)

Jin Jing [MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, Sun Yat-sen University, Guangzhou 510275 (China); Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Kowloon (Hong Kong); Yang Lihua [MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, Sun Yat-sen University, Guangzhou 510275 (China); Chan, Sidney M.N. [Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Kowloon (Hong Kong); Luan Tiangang, E-mail: cesltg@mail.sysu.edu.cn [MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, Sun Yat-sen University, Guangzhou 510275 (China); Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Kowloon (Hong Kong); Li Yan [MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, Sun Yat-sen University, Guangzhou 510275 (China); Tam, Nora F.Y., E-mail: bhntam@cityu.edu.hk [Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Kowloon (Hong Kong)

2011-01-30

The removal and degradation of tributyltin (TBT) by alginate immobilized Chlorella vulgaris has been evidenced in our previously published work. The present study was further to investigate the effect of spiked nutrient concentrations on the TBT removal capacity and degradation in the same alginate immobilized C. vulgaris. During the 14-d experiment, compared to the control (natural river water), the spiked nutrient groups (50% or 100% nutrients of the commercial Bristol medium as the reference, marked as 1/2N or 1N) showed more rapid cell proliferation of microalgae and higher TBT removal rate. Moreover, significantly more TBT was adsorbed onto the alginate matrix, but less TBT was taken up by the algal cells of the nutrient groups than that of the control. Mass balance data showed that TBT was lost as inorganic tin in the highest degree in 1N group, followed by 1/2N group and the least was in the control, but the relative abundance of the intermediate products of debutylation (dibutyltin and monobutyltin) were comparable among three groups. In conclusion, the addition of nutrients in contaminated water stimulated the growth and physiological activity of C. vulgaris immobilized in alginate beads and improved its TBT degradation efficiency.

Effect of nutrients on the biodegradation of tributyltin (TBT) by alginate immobilized microalga, Chlorella vulgaris, in natural river water.

Science.gov (United States)

Jin, Jing; Yang, Lihua; Chan, Sidney M N; Luan, Tiangang; Li, Yan; Tam, Nora F Y

2011-01-30

The removal and degradation of tributyltin (TBT) by alginate immobilized Chlorella vulgaris has been evidenced in our previously published work. The present study was further to investigate the effect of spiked nutrient concentrations on the TBT removal capacity and degradation in the same alginate immobilized C. vulgaris. During the 14-d experiment, compared to the control (natural river water), the spiked nutrient groups (50% or 100% nutrients of the commercial Bristol medium as the reference, marked as 1/2N or 1N) showed more rapid cell proliferation of microalgae and higher TBT removal rate. Moreover, significantly more TBT was adsorbed onto the alginate matrix, but less TBT was taken up by the algal cells of the nutrient groups than that of the control. Mass balance data showed that TBT was lost as inorganic tin in the highest degree in 1N group, followed by 1/2N group and the least was in the control, but the relative abundance of the intermediate products of debutylation (dibutyltin and monobutyltin) were comparable among three groups. In conclusion, the addition of nutrients in contaminated water stimulated the growth and physiological activity of C. vulgaris immobilized in alginate beads and improved its TBT degradation efficiency. Copyright © 2010 Elsevier B.V. All rights reserved.

[Safety and efficacy of polyethylene glycol 3350 plus electrolytes for the treatment of functional constipation in children].

Science.gov (United States)

Infante Pina, D; Miserachs Barba, M; Segarra Canton, O; Alvarez Beltrán, M; Redecillas Ferreiro, S; Vilalta Casas, R; Nieto Rey, J L

2011-08-01

Polyethylene glycol 3350 plus electrolytes (PEG+E) efficacy has been validated in some studies, but not many have evaluated its safety in children. The aim of our study was to evaluate the safety; renal, malabsorption or excessive production of gas and efficacy of PEG+E treatment in our paediatric population. Fifteen patients who suffered functional constipation (Rome III criteria) were evaluated. Median age was 6.2 years (r 2-9). All patients had normal renal function. PEG+E were administered for 4 weeks (4WP). The mean dose was 0.44 g/kg/day, titrated according to age, weight and response. Urine screens (sodium and osmolality) were performed at the beginning and 4WP. Stool sample NIRA (near-infrared reflectance analysis) and hydrogen breath test analysis samples were performed at 4WP. To analyse the efficacy of the treatment, the number of stools per week and stool form type (Bristol stool scale) were recorded. The number of stools per week was higher after 4 weeks (2.46 ± 0.71 vs 5.29 ± 1.68, PPEG+E can be recommended for the treatment of functional constipation in children. Copyright © 2010 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

Breaking open the set top box

Science.gov (United States)

Banks, David; Wiley, Anthony; Catania, Nicolas; Coles, Alastair N.; Smith, Duncan; Baynham, Simon; Deliot, Eric; Chidzey, Rod

1998-02-01

In this paper we describe the work being done at HP Labs Bristol in the area of home networks and gateways. This work is based on the idea of breaking open the set top box by physically separating the access network specific functions from the application specific functions. The access network specific functions reside in an access network gateway that can be shared by many end user devices. The first section of the paper present the philosophy behind this approach. The end user devices and the access network gateways must be interconnected by a high bandwidth network which can offer a bounded delay service for delay sensitive traffic. We are advocating the use of IEEE 1394 for this network, and the next section of the paper gives a brief introduction to this technology. We then describe a prototype digital video broadcasting satellite compliant gateway that we have built. This gateway could be used, for example, by a PC for receiving a data service or by a digital TV for receiving an MPEG-2 video service. A control architecture is the presented which uses a PC application to provide a web based user interface to the system. Finally, we provide details of our work on extending the reach of IEEE 1394 and its standardization status.

Mapping determinants of gene expression plasticity by genetical genomics in C. elegans.

Directory of Open Access Journals (Sweden)

Yang Li

2006-12-01

Full Text Available Recent genetical genomics studies have provided intimate views on gene regulatory networks. Gene expression variations between genetically different individuals have been mapped to the causal regulatory regions, termed expression quantitative trait loci. Whether the environment-induced plastic response of gene expression also shows heritable difference has not yet been studied. Here we show that differential expression induced by temperatures of 16 degrees C and 24 degrees C has a strong genetic component in Caenorhabditis elegans recombinant inbred strains derived from a cross between strains CB4856 (Hawaii and N2 (Bristol. No less than 59% of 308 trans-acting genes showed a significant eQTL-by-environment interaction, here termed plasticity quantitative trait loci. In contrast, only 8% of an estimated 188 cis-acting genes showed such interaction. This indicates that heritable differences in plastic responses of gene expression are largely regulated in trans. This regulation is spread over many different regulators. However, for one group of trans-genes we found prominent evidence for a common master regulator: a transband of 66 coregulated genes appeared at 24 degrees C. Our results suggest widespread genetic variation of differential expression responses to environmental impacts and demonstrate the potential of genetical genomics for mapping the molecular determinants of phenotypic plasticity.

Out of Our Heads! Four perspectives on the curation of an on-line exhibition of medically themed artwork by UK medical undergraduates

Science.gov (United States)

Thompson, Trevor; van de Klee, Danny; Lamont-Robinson, Catherine; Duffin, Will

2010-01-01

The Medical School at Bristol University is noted for offering, and in some instances requiring, its students to work creatively with medical themes. Students, artists, educationalists and a web designer have worked to create an on-line exhibition of the resulting creative output. This can be viewed at www.outofourheads.net. This site is a themed repository of poetry, prose, drawings, paintings, cartoons, films, music, dance and rap. Most works come with commentaries that can be as illuminating as the works they describe. The site invites comment and welcomes new postings from anyone connected to medicine. As an alternative to the conventional pedagogical report, and in keeping with the subject matter, in this paper we tell the story of this unique educational enterprise through the narratives of four of its principle architects. The ‘Teacher's Tale’, the ‘Designer's Tale’, the ‘Curator's Tale’ and the ‘Artist's Tale’ offer different, personal, tellings of how the site came to be. Each tale contains hypertext links to notable works on the site some of which have become teaching resources within the institution. This paper is of relevance to anyone who seeks to explore and champion the human insights of this privileged community. PMID:21321667

TIPTOPbase: the Iron Project and the Opacity Project Atomic Database

Science.gov (United States)

Mendoza, Claudio; Nahar, Sultana; Pradhan, Anil; Seaton, Micheal; Zeippen, Claude

2001-05-01

The Opacity Project, the IRON Project, and the RmaX Network (The Opacity Project Team, Vol.1,2), IOPP, Bristol (1995,1996); Hummer et al., Astron. Astrophys. 279, 298 (1993) are international computational efforts concerned with the production of high quality atomic data for astrophysical applications. Research groups from Canada, France, Germany, UK, USA and Venezuela are involved. Extensive data sets containing accurate energy levels, f-values, A-values, photoionisation cross sections, collision strengths, recombination rates, and opacitites have been computed for cosmically abundant elements using state-of-the-art atomic physics codes. Their volume, completeness and overall accuracy are presently unmatched in the field of laboratory astrophysics. Some of the data sets have been available since 1993 from a public on-line database service referred to as TOPbase (Cunto et al Astron. Astrophys. 275), L5 (1993), ( http://cdsweb.u-strasbg.fr/OP.html at CDS France, and http://heasarc.gsfc.nasa.gov/topbase, at NSAS USA). We are currently involved in a major effort to scale the existing database services to develop a robust platform for the high-profile dissemination of atomic data to the scientific community within the next 12 months. (Partial support from the NSF and NASA is acknowledged.)

The Science on Saturday Program at Princeton Plasma Physics Laboratory

Science.gov (United States)

Bretz, N.; Lamarche, P.; Lagin, L.; Ritter, C.; Carroll, D. L.

1996-11-01

The Science on Saturday Program at Princeton Plasma Physics Laboratory consists of a series of Saturday morning lectures on various topics in science by scientists, engineers, educators, and others with an interesting story. This program has been in existence for over twelve years and has been advertised to and primarily aimed at the high school level. Topics ranging from superconductivity to computer animation and gorilla conservation to pharmaceutical design have been covered. Lecturers from the staff of Princeton, Rutgers, AT and T, Bristol Meyers Squibb, and many others have participated. Speakers have ranged from Nobel prize winners, astronauts, industrialists, educators, engineers, and science writers. Typically, there are eight to ten lectures starting in January. A mailing list has been compiled for schools, science teachers, libraries, and museums in the Princeton area. For the past two years AT and T has sponsored buses for Trenton area students to come to these lectures and an effort has been made to publicize the program to these students. The series has been very popular, frequently overfilling the 300 seat PPPL auditorium. As a result, the lectures are videotaped and broadcast to a large screen TV for remote viewing. Lecturers are encouraged to interact with the audience and ample time is provided for questions.

Age affects not only metabolome but also metal toxicity in Scenedesmus quadricauda cultures.

Science.gov (United States)

Kováčik, Jozef; Klejdus, Bořivoj; Babula, Petr; Hedbavny, Josef

2016-04-05

Responses of Scenedesmus quadricauda grown in vitro and differing in age (old culture-13 months, young culture-1 month) to short-term cadmium (Cd) or nickel (Ni) excess (24h) were compared. Higher age of the culture led to lower amount of chlorophylls, ascorbic acid and glutathione but higher signal of ROS. Surprisingly, sucrose was detected using DART-Orbitrap MS in both old and young culture and subsequent quantification confirmed its higher amount (ca. 3-times) in the old culture. Cd affected viability and ROS amount more negatively than Ni that could arise from excessive Cd uptake which was also higher in all treatments than in respective Ni counterparts. Surprisingly, nitric oxide was not extensively different in response to age or metals. Strong induction of phytochelatin 2 is certainly Cd-specific response while Ni also elevated ascorbate content. Krebs cycle acids were more accumulated in the young culture but they were rather elevated in the old culture (citric acid under Ni excess). We conclude that organic solid 'Milieu Bristol' medium we tested is suitable for long-term storage of unicellular green algae (also successfully tested for Coccomyxa sp. and Parachlorella sp.) and the impact of age on metal uptake may be useful for bioremediation purposes. Copyright © 2015 Elsevier B.V. All rights reserved.

Consumption choice by bears feeding on salmon.

Science.gov (United States)

Gende, S M; Quinn, T P; Willson, M F

2001-05-01

Consumption choice by brown (Ursus arctos) and black bears (U. americanus) feeding on salmon was recorded for over 20,000 bear-killed fish from 1994 to 1999 in Bristol Bay (sockeye salmon, Oncorhynchus nerka) and southeastern Alaska (pink, O. gorbuscha and chum salmon O. keta). These data revealed striking patterns of partial and selective consumption that varied with relative availability and attributes of the fish. As the availability of salmon decreased, bears consumed a larger proportion of each fish among both years and habitats. When availability was high (absolute number and density of salmon), bears consumed less biomass per captured fish, targeting energy-rich fish (those that had not spawned) or energy-rich body parts (eggs in females; brain in males). In contrast, individual fish were consumed to a much greater extent, regardless of sex or spawning status, in habitats or years of low salmon availability. The proportion of biomass consumed per fish was similar for males and females, when spawning status was statistically controlled, but bears targeted different body parts: the body flesh, brain and dorsal hump in males and the roe in females. Bears thus appeared to maximize energy intake by modifying the amount and body parts consumed, based on availability and attributes of spawning salmon.

Estimating attractiveness for abuse of a not-yet-marketed "abuse-deterrent" prescription opioid formulation.

Science.gov (United States)

Butler, Stephen F; Black, Ryan; Grimes Serrano, Jill M; Folensbee, Lesley; Chang, Alan; Katz, Nathaniel

2010-01-01

The present study builds on research to model abusers' perceptions of particular analgesics' attractiveness for abuse and extends these methods to derive an estimate of attractiveness for abuse of a not-yet-marketed abuse-deterrent formulation (ADF) of a prescription opioid (Remoxy), Pain Therapeutics, Inc., San Mateo, CA, and King Pharmaceuticals, Inc., Bristol, TN). In a previous study, the Opioid Attractiveness Technology Scaling (OATS) method identified, from a drug abuser's point of view, the particular features of a prescription opioid relevant to its attractiveness for recreational use. A second online sample rated the extent to which these features applied to particular products they had actually used/abused. These data were used to model the abusers' overall preference for prescription opioids they had used/abused. In the present study, this method was applied to a not-yet-marketed ADF using substance abuse counselors as proxies for prescription opioid abusers. Thirty-eight counselors were given materials describing the new ADF along with four known products. Thirty-two counselors demonstrated sufficient agreement with abusers' ratings of the overall attractiveness of these drugs. The overall model yielded a significant pseudo R(2) of 0.15 (P marketing estimates of attractiveness for abuse of not-yet-marketed ADFs.

Dislocations and other topological oddities

Science.gov (United States)

Pieranski, Pawel

2016-03-01

We will show that the book Dislocations by Jacques Friedel, published half a century ago, can still be recommended, in agreement with the author's intention, as a textbook ;for research students at University and for students at engineering schools as well as for research engineers;. Indeed, today dislocations are known to occur not only in solid crystals but also in many other systems discovered more recently such as colloidal crystals or liquid crystals having periodic structures. Moreover, the concept of dislocations is an excellent starting point for lectures on topological defects occurring in systems equipped with order parameters resulting from broken symmetries: disclinations in nematic or hexatic liquid crystals, dispirations in chiral smectics or disorientations in lyotropic liquid crystals. The discussion of dislocations in Blue Phases will give us an opportunity to call on mind Sir Charles Frank, friend of Jacques Friedel since his Bristol years, who called these ephemeral mesophases ;topological oddities;. Being made of networks of disclinations, Blue Phases are similar to Twist Grain Boundary (TGB) smectic phases, which are made of networks of screw dislocations and whose existence was predicted by de Gennes in 1972 on the basis of the analogy between smectics and superconductors. We will stress that the book by Jacques Friedel contains seeds of this analogy.

Human anatomy: let the students tell us how to teach.

Science.gov (United States)

Davis, Christopher R; Bates, Anthony S; Ellis, Harold; Roberts, Alice M

2014-01-01

Anatomy teaching methods have evolved as the medical undergraduate curriculum has modernized. Traditional teaching methods of dissection, prosection, tutorials and lectures are now supplemented by anatomical models and e-learning. Despite these changes, the preferences of medical students and anatomy faculty towards both traditional and contemporary teaching methods and tools are largely unknown. This study quantified medical student and anatomy faculty opinion on various aspects of anatomical teaching at the Department of Anatomy, University of Bristol, UK. A questionnaire was used to explore the perceived effectiveness of different anatomical teaching methods and tools among anatomy faculty (AF) and medical students in year one (Y1) and year two (Y2). A total of 370 preclinical medical students entered the study (76% response rate). Responses were quantified and intergroup comparisons were made. All students and AF were strongly in favor of access to cadaveric specimens and supported traditional methods of small-group teaching with medically qualified demonstrators. Other teaching methods, including e-learning, anatomical models and surgical videos, were considered useful educational tools. In several areas there was disharmony between the opinions of AF and medical students. This study emphasizes the importance of collecting student preferences to optimize teaching methods used in the undergraduate anatomy curriculum. © 2013 American Association of Anatomists.

Long-term follow-up of nutritional status, pancreatic function, and morphological changes of the pancreatic remnant after pancreatic tumor resection in children.

Science.gov (United States)

Sugito, Kiminobu; Furuya, Takeshi; Kaneda, Hide; Masuko, Takayuki; Ohashi, Kensuke; Inoue, Mikiya; Ikeda, Taro; Koshinaga, Tsugumichi; Tomita, Ryouichi; Maebayashi, Toshiya

2012-05-01

The objectives of the present study were to determine nutritional status, pancreatic function, and morphological changes of the pancreatic remnant after pancreatic tumor resection in children. The nutritional status was evaluated by the patterns of growth. Pancreatic function was evaluated by using a questionnaire, the Bristol stool form chart, the serum levels of fasting blood glucose, and hemoglobin A1c (HbA1c). Morphological changes of the pancreatic remnant were evaluated by computed tomography, magnetic resonance image, or magnetic resonance cholangiopancreatography. The present study consisted of 6 patients with pancreatic tumor (5 solid pseudopapillary tumors of the pancreas and 1 pancreatoblastoma) who underwent the following operations: tumor enucleation (3), distal pancreatectomy with splenectomy (1), and pylorus-preserving pancreatoduodenectomy (PPPD [2]). The serum levels of HbA1c have been gradually elevated in 2 patients with PPPD. A significant decrease in pancreatic parenchymal thickness and dilatation of the main pancreatic duct were observed in 2 patients with PPPD. Endocrine pancreatic insufficiency after PPPD may be explainable by obstructive pancreatitis after operation. Taking together the results of pancreatic endocrine function and morphological changes of pancreatic remnant after PPPD, tumor enucleation should be considered as surgical approach in children with pancreas head tumor whenever possible.

Publicising chemistry in a multicultural society through chemistry outreach

Directory of Open Access Journals (Sweden)

Joyce D. Sewry

2011-11-01

Full Text Available Given the emphasis in Higher Education on community engagement in South Africa and the importance of international collaboration, we discuss a joint approach to chemistry outreach in two countries on two continents with widely differing target school audiences. We describe the history of the partnership between the chemistry departments at Rhodes University and the University of Bristol and provide an outline of the chemistry content of their outreach initiatives, the modes of delivery, the advantages to both departments and their students for involvement in various levels of outreach, the challenges they still face and additional opportunities that such work facilitated. The lecture demonstration ‘A Pollutant’s Tale’ was presented to thousands of learners all over the world, including learners at resource-deprived schools in South Africa. Challenges to extend outreach activities in South Africa include long travelling distances, as well as a lack of facilities (such as school halls and electricity at schools. Outreach activities not only impacted on the target audience of young learners, they also impacted upon the postgraduate and other chemistry students taking part in these initiatives. This collaboration strengthened both institutions and their outreach work and may also lead to chemistry research collaborations between the academics involved.

Effect of nutrients on the biodegradation of tributyltin (TBT) by alginate immobilized microalga, Chlorella vulgaris, in natural river water

International Nuclear Information System (INIS)

Jin Jing; Yang Lihua; Chan, Sidney M.N.; Luan Tiangang; Li Yan; Tam, Nora F.Y.

2011-01-01

The removal and degradation of tributyltin (TBT) by alginate immobilized Chlorella vulgaris has been evidenced in our previously published work. The present study was further to investigate the effect of spiked nutrient concentrations on the TBT removal capacity and degradation in the same alginate immobilized C. vulgaris. During the 14-d experiment, compared to the control (natural river water), the spiked nutrient groups (50% or 100% nutrients of the commercial Bristol medium as the reference, marked as 1/2N or 1N) showed more rapid cell proliferation of microalgae and higher TBT removal rate. Moreover, significantly more TBT was adsorbed onto the alginate matrix, but less TBT was taken up by the algal cells of the nutrient groups than that of the control. Mass balance data showed that TBT was lost as inorganic tin in the highest degree in 1N group, followed by 1/2N group and the least was in the control, but the relative abundance of the intermediate products of debutylation (dibutyltin and monobutyltin) were comparable among three groups. In conclusion, the addition of nutrients in contaminated water stimulated the growth and physiological activity of C. vulgaris immobilized in alginate beads and improved its TBT degradation efficiency.

Safe transport of radioactive material

International Nuclear Information System (INIS)

1990-01-01

Recently the Agency redefined its policy for education and training in radiation safety. The emphasis is now on long-term strategic planning of general education and training programmes. In line with this general policy the Agency's Standing Advisory Group for the Safe Transport of Radioactive Material (SAGSTRAM) in its 7th meeting (April 1989) agreed that increased training activity should be deployed in the area of transport. SAGSTRAM specifically recommended the development of a standard training programme on this subject area, including audio-visual aids, in order to assist Member States in the implementation of the Agency's Regulations for the Safe Transport of Radioactive Material. This training programme should be substantiated by a biennial training course which is thought to be held either as an Interregional or a Regional Course depending on demand. This training manual, issued as a first publication in the Training Course Series, represents the basic text material for future training courses in transport safety. The topic areas covered by this training manual and most of the texts have been developed from the course material used for the 1987 Bristol Interregional Course on Transport Safety. The training manual is intended to give guidance to the lecturers of a course and will be provided to the participants for retention. Refs, figs and tabs

Gauge fields with respect to d = (3+1) in the Kaluza-Klein theories and in the spin-charge-family theory

Energy Technology Data Exchange (ETDEWEB)

Lukman, Dragan; Mankoc Borstnik, Norma Susana [University of Ljubljana, Department of Physics, FMF, Ljubljana (Slovenia)

2017-04-15

It is shown that in the spin-charge-family theory (Mankoc Borstnik in arXiv:1607.01618v2, 2016, Phys Rev D 91:065004. arxiv:1409.7791, 2015, J Mod Phys 6:2244. doi:10.4236/jmp.2015.615230. arXiv: 1409.4981, 2015, J Mod Phys 4:823. doi:10.4236/jmp.2013.46113. arxiv:1312.1542, 2013, arxiv:1409.4981, 2014) as well as in all the Kaluza-Klein like theories (Blagojevic in Gravitation and gauge symmetries, IoP Publishing, Bristol, 2002, An introduction to Kaluza-Klein theories, World Scientific, Singapore, 1983), vielbeins and spin connections manifest in d = (3+1) space equivalent vector gauge fields, when space with d ≥ 5 has a large enough symmetry. The authors demonstrate this equivalence in spaces with the symmetry of the metric tensor in the space out of d = (3+1)-g{sup στ} = η{sup στ} f{sup 2} - for any scalar function f of the coordinates x{sup σ}, where x{sup σ} denotes the coordinates of space out of d = (3+1). Also the connection between vielbeins and scalar gauge fields in d = (3+1) (offering the explanation for the Higgs scalar) is discussed. (orig.)

The association of birth order with later body mass index and blood pressure: a comparison between prospective cohort studies from the United Kingdom and Brazil.

Science.gov (United States)

Howe, L D; Hallal, P C; Matijasevich, A; Wells, J C; Santos, I S; Barros, A J D; Lawlor, D A; Victora, C G; Smith, G D

2014-07-01

Previous studies have found greater adiposity and cardiovascular risk in first born children. The causality of this association is not clear. Examining the association in diverse populations may lead to improved insight. We examine the association between birth order and body mass index (BMI), systolic and diastolic blood pressure (SBP/DBP) in the 2004 Pelotas cohort from southern Brazil and the Avon Longitudinal Study of Parents and Children (ALSPAC) from Bristol, south-west England, restricting analysis to families with two children in order to remove confounding by family size. No consistent differences in BMI, SBP or DBP were observed comparing first and second born children. Within the Pelotas 2004 cohort, first born females were thinner, with lower SBP and DBP; for example, mean difference in SBP comparing first with second born was -0.979 (95% confidence interval -2.901 to 0.943). In ALSPAC, first born females had higher BMI, SBP and DBP. In both cohorts, associations tended to be in the opposite direction in males, although no statistical evidence for gender interactions was found. The findings do not support an association between birth order and BMI or blood pressure. Differences to previous studies may be explained by differences in populations and/or confounding by family size in previous studies.

A spaceborne inventory of volcanic activity in Antarctica and southern oceans, 2000-10

Science.gov (United States)

Patrick, Matthew R.; Smellie, John L.

2015-01-01

Of the more than twenty historically active volcanoes in Antarctica and the sub-Antarctic region only two, to our knowledge, host any ground-based monitoring instruments. Moreover, because of their remoteness, most of the volcanoes are seldom visited, thus relegating the monitoring of volcanism in this region almost entirely to satellites. In this study, high temporal resolution satellite data from the Hawaii Institute of Geophysics and Planetology's MODVOLC system using MODIS (Moderate Resolution Imaging Spectroradiometer) are complemented with high spatial resolution data (ASTER, or Advanced Spaceborne Thermal Emission and Reflection Radiometer, and similar sensors) to document volcanic activity throughout the region during the period 2000–10. Five volcanoes were observed in eruption (Mount Erebus, Mount Belinda, Mount Michael, Heard Island and McDonald Island), which were predominantly low-level and effusive in nature. Mount Belinda produced tephra, building a cinder cone in addition to an extensive lava field. Five volcanoes exhibited detectable thermal, and presumed fumarolic, activity (Deception, Zavodovski, Candlemas, Bristol, and Bellingshausen islands). A minor eruption reported at Marion Island was not detected in our survey due to its small size. This study also discovered a new active vent on Mount Michael, tracked dramatic vent enlargement on Heard Island, and provides an improved picture of the morphology of some of the volcanoes.

Parenting styles, parenting practices, and physical activity in 10- to 11-year olds.

Science.gov (United States)

Jago, Russell; Davison, Kirsten K; Brockman, Rowan; Page, Angie S; Thompson, Janice L; Fox, Kenneth R

2011-01-01

The objective of this study was to determine whether parenting styles and practices are associated with children's physical activity. Cross-sectional survey of seven hundred ninety-two 10- to 11-year-old UK children in Bristol (UK) in 2008-2009 was conducted. Accelerometer-assessed physical activity and mean minutes of moderate-to-vigorous physical activity (mean MVPA) and mean counts per minute (mean CPM) were obtained. Maternal parenting style and physical activity parenting practices were self-reported. In regression analyses, permissive parenting was associated with higher mean MVPA among girls (+6.0 min/day, pparents. Maternal logistic support was associated with mean CPM for girls (+36.2 counts/min, p=0.001), while paternal logistic support was associated with boys' mean MVPA (+4.0 min/day, p=0.049) and mean CPM (+55.7 counts/min, p=0.014). Maternal permissive parenting was associated with higher levels of physical activity than authoritative parenting, but associations differed by child gender and type of physical activity. Maternal logistic support was associated with girls' physical activity, while paternal logistic support was associated with boys' physical activity. Health professionals could encourage parents to increase logistic support for their children's physical activity. Copyright © 2010 Elsevier Inc. All rights reserved.

Training simulator takes to the road

International Nuclear Information System (INIS)

Curtis, J.; Moore, R.

1993-01-01

A peripatetic approach to technical training is being adopted by Nuclear Electric in the use with its plants to adopt a compact, mobile simulator for certain training applications. Unlike the fixed digital power plant simulators housed at the company's Oldbury Nuclear Training Center near Bristol and the Cliff Quay Training Centre in Ipswich, these are designed to travel around the country to server users. The first of the mobile simulators will be used to train operators in the safe switching of high voltage apparatus between power stations and the UK National Grid transmission system. The simulator comprises a four-piece, four-position suite of equipment, providing power station and sub-station control room panels and a grid control module, all of which are managed by a tutor's station. It is driven by six IBM PC compatibles - four 486 and two 386 machines - operating under MS-DOS 5 and to a program written in Turbo Pascal. The simulator packs away inside a trailer, which can then be towed behind the tutor's car to its next location. One person can unload and set up the equipment in 30 minutes. Fully staffed, the simulator can be used with up to six operators or for individual tuition at each work station. (author)

Towards a team-based, collaborative approach to embedding e-learning within undergraduate nursing programmes.

Science.gov (United States)

Kiteley, Robin J; Ormrod, Graham

2009-08-01

E-learning approaches are incorporated in many undergraduate nursing programmes but there is evidence to suggest that these are often piecemeal and have little impact on the wider, nurse education curriculum. This is consistent with a broader view of e-learning within the higher education (HE) sector, which suggests that higher education institutions (HEIs) are struggling to make e-learning a part of their mainstream delivery [HEFCE, 2005. HEFCE Strategy for E-Learning 2005/12. Bristol, UK, Higher Education Funding Council for England (HEFCE). [online] Available at: Accessed: 30 May 07]. This article discusses some of the challenges that face contemporary nurse education and seeks to account for reasons as to why e-learning may not be fully embedded within the undergraduate curriculum. These issues are considered within a wider debate about the need to align e-learning approaches with a shift towards a more student focused learning and teaching paradigm. The article goes on to consider broader issues in the literature on the adoption, embedding and diffusion of innovations, particularly in relation to the value of collaboration. A collaborative, team-based approach to e-learning development is considered as a way of facilitating sustainable, responsive and multidisciplinary developments within a field which is constantly changing and evolving.

Resilience-based performance metrics for water resources management under uncertainty

Science.gov (United States)

Roach, Tom; Kapelan, Zoran; Ledbetter, Ralph

2018-06-01

This paper aims to develop new, resilience type metrics for long-term water resources management under uncertain climate change and population growth. Resilience is defined here as the ability of a water resources management system to 'bounce back', i.e. absorb and then recover from a water deficit event, restoring the normal system operation. Ten alternative metrics are proposed and analysed addressing a range of different resilience aspects including duration, magnitude, frequency and volume of related water deficit events. The metrics were analysed on a real-world case study of the Bristol Water supply system in the UK and compared with current practice. The analyses included an examination of metrics' sensitivity and correlation, as well as a detailed examination into the behaviour of metrics during water deficit periods. The results obtained suggest that multiple metrics which cover different aspects of resilience should be used simultaneously when assessing the resilience of a water resources management system, leading to a more complete understanding of resilience compared with current practice approaches. It was also observed that calculating the total duration of a water deficit period provided a clearer and more consistent indication of system performance compared to splitting the deficit periods into the time to reach and time to recover from the worst deficit events.

Obituary: Edward W. Burke, Jr. (1924-2011)

Science.gov (United States)

Bloomer, Raymond, Jr.

2011-12-01

Dr. Edward W. Burke Jr. passed away on June 15, 2011, after suffering a heart attack. Dr. Burke devoted his professional life to the research and teaching of physics and astronomy at King College in Bristol, Tennessee. Edward W. Burke, Jr., was born in Macon, Georgia, on September 16, 1924. He was a Navy veteran, having been commissioned as an ensign in 1944. He served in the Pacific near the end of World War II. He proceeded to complete his undergraduate degree in mathematics from Presbyterian College in 1947 and pursued the M.S. and Ph.D. in physics (1949 and 1954, respectively) at the University of Wisconsin. Under the direction of Professor Julian Mack, his thesis was titled "Isotope Shift in the Spectra of Boron." Although he did research in atomic spectra in the early part of his career, his interest in astronomy and variable stars in particular were his primary interests during his long academic career. Dr. Burke began his illustrious career at King College in 1949. He initiated the astronomy program there in 1950, included constructing a 12.5 inch Newtonian telescope, homemade as was most everything in those days. Many of his students learned about photometry at the Burke Observatory on the college campus. Burke was known for his trips to the Kitt Peak and Lowell observatories accompanied by undergraduate students on his trips, all of which were made by automobile which he preferred over flying. His initial interest in Ap stars later broadened into variable and especially eclipsing binary stars. His motivation was maintained by his desire to have his students experience basic research and to spark their interest in advanced degrees. Numerous students achieved advanced science and medical degrees because of Burke's encouragement and mentoring. In 1959, Dr. Burke was awarded a Fulbright professorship and traveled to Chile where he taught physics for a year in the Engineering School at the University of Chile in Santiago. He worked to establish a physics

Crescimento de mudas de gipsofila em diferentes substratos Development of young plants of gypsophila in different substrates

Directory of Open Access Journals (Sweden)

Nair Bosa

2003-09-01

Full Text Available Dentro da horticultura um dos ramos que tem se expandido nos últimos anos é a floricultura, em função de sua rentabilidade. Neste sentido, o estudo e uso dos substratos para produção de mudas torna-se de grande importância, pois da qualidade da muda depende o resultado do produto final. Considerando que a qualidade de um substrato é o resultado de suas propriedades químicas e físicas, efetuou-se a caracterização dos mesmos. Este experimento foi realizado com o objetivo de avaliar o crescimento de plantas de Gypsophila paniculata cv. Bristol Fairy em diferentes substratos. Os tratamentos (seis substratos foram dispostos em delineamento de blocos casualizados, com parcelas subdivididas no tempo, com quatro repetições. Cada parcela constou de 22 plantas, totalizando 588 mudas. Nos substratos, foram efetuadas as análises físico-químicas: densidade seca, porosidade total, espaço de aeração, água disponível, água facilmente disponível, pH, condutividade elétrica e capacidade de troca de cátions. As avaliações nas plantas foram realizadas semanalmente (7-35 dias e constituíram-se da taxa de sobrevivência, volume de raízes, massa fresca e seca da parte aérea e da raiz. Os resultados indicaram que a característica disponibilidade de água otimiza a aclimatização de Gypsophila paniculata. Os melhores resultados para produção de mudas foram obtidos com os substratos FE1 (perlita + turfa e FE4 (casca de pinus + perlita + turfa.Floriculture is one of the branches in horticulture that has expanded in the last years because of its profitability. The study and the use of substrates for producing young plants are important, once the gypsophila production depends on young plants quality. Considering that the quality of a substrate is the result of its chemical and physical properties, the characterisation of these properties was made. This trial was carried out to evaluate the growth of Gypsophila paniculala cv. Bristol Fairy